The implication of follicular lymphoma patients receiving allogeneic stem cell transplantation from donors carrying t(14;18)-positive cells.

Science.gov (United States)

McGregor, D K; Keever-Taylor, C A; Bredeson, C; Schur, B; Vesole, D H; Logan, B; Chang, C-C

2005-06-01

We performed real-time quantitative polymerase chain reaction (RQ-PCR) in peripheral blood (PB) and/or bone marrow (BM) samples collected pre- and post transplant from 23 recipient-donor pairs receiving allogeneic stem cell transplantation (allo-SCT) for follicular lymphoma (FL). Of 23 donors, 11 had a PB and/or BM sample positive for t(14;18) (BCL2/IGH fusion) at low levels (donors with (n=11) and those without (n=12) detectable t(14:18) cells were similar in age, sex, and disease status pretransplant. No differences in the incidence of graft-versus-host-disease (GVHD), delayed engraftment, relapse rate, disease-free survival and overall survival were identified between the groups. Two recipients without detectable t(14;18) cells pre-transplant showed detectable t(14;18) cells at 2 and 11 years after receiving grafts from donors with t(14:18) cells. Neither patient developed FL 1.5 and 2 years after the emergence of t(14;18) cells. Although the sample size is relatively small, our findings suggest that individuals carrying t(14;18) cells may not be excluded as donors given the lack of an association of t(14;18) detected in donors with adverse clinical outcome. It may be necessary to screen for the donor's t(14;18) status before using t(14;18) for monitoring minimal residual disease by RQ-PCR to exclude the possibility of confounding donor's t(14;18) clone.

14th International Conference on Software Engineering, Artificial Intelligence Research, Management and Applications

CERN Document Server

2016-01-01

This edited book presents scientific results of the 14th International Conference on Software Engineering, Artificial Intelligence Research, Management and Applications (SERA 2016) held on June 8-10, 2016 at Towson University, USA. The aim of this conference was to bring together researchers and scientists, businessmen and entrepreneurs, teachers, engineers, computer users, and students to discuss the numerous fields of computer science and to share their experiences and exchange new ideas and information in a meaningful way. Research results about all aspects (theory, applications and tools) of computer and information science, and to discuss the practical challenges encountered along the way and the solutions adopted to solve them. The conference organizers selected the best papers from those papers accepted for presentation at the conference. The papers were chosen based on review scores submitted by members of the program committee, and underwent further rigorous rounds of review. This publication capture...

Proceedings of the workshop on severe accident research held in Japan (SARJ-98)

Energy Technology Data Exchange (ETDEWEB)

Sugimoto, Jun [ed.

1999-07-01

The Workshop on Severe Accident Research held in Japan (SARJ-98) was taken place at Hotel Lungwood on November 4-6, 1998, and attended by 181 participants from 13 countries. The 63 papers, which cover wide areas of severe accident research both in experiments and analyses, such as in-vessel melt retention, fuel-coolant interaction, fission products behavior, structural integrity, containment behavior, computer simulations, and accident management, are indexed individually. (J.P.N.)

Radioactive waste management practices and issues in developing countries. Proceedings of a seminar held in Beijing, China, 10-14 October 1994

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-12-01

Radioactive waste is generated from the production of nuclear energy and from the use of radioactive materials in industrial applications, research and medicine. The importance of safe management of radioactive waste for the protection of human health and the environment has long been recognized and considerable experience has been gained in this field. While this programme is developing and various related Safety Series publications are becoming available, it is important to compare the existing national waste management regulations, organization, technologies and methods with internationally accepted requirements and practices. In response to the growing interest in this area, the IAEA, in co-operation with the Government of the People`s Republic of China, held a Seminar on Radioactive Waste Management Practices and Issues in Developing Countries at Beijing from 10 to 14 October 1994. Refs, figs and tabs.

Proceedings of the workshop on severe accident research held in Japan (SARJ-97)

Energy Technology Data Exchange (ETDEWEB)

Sugimoto, Jun [ed.

1998-05-01

The Workshop on Severe Accident Research held in Japan (SARJ-97) was taken place at Pacifico Yokohama on October 6 - 8, 1997, and attended by 180 participants from 15 countries and one international organizations. The 59 papers, which cover wide areas of severe accident research both in experiments and analysis, such as in-vessel melt retention, fuel-coolant interaction, fission products behavior, structural integrity, containment behavior, computer simulations, and accident management, are indexed individually. (J.P.N.)

Implications of the 14C(α,γ)18O reaction for nonstandard big bang nucleosynthesis

International Nuclear Information System (INIS)

Gai, M.

1992-01-01

The thermonuclear burning rates for the 14 C(α,γ) 18 O radiative capture reaction are calculated at temperatures (0.3 - state, at approximately 9.0 MeV in 18 O as would be deduced from the Yale-Michigan State University measurement of the beta-delayed alpha-particle emission of 18 N and suggested by the Notre Dame-Caltech measurement of the nonresonant 14 C(α,γ) 18 O cross section. The gamma widths of the proposed broad state is estimated using the Alhassid, Gai, and Bertsch sum rule, and an experimental study is proposed

Peat Research Seminar

International Nuclear Information System (INIS)

1993-01-01

The VTT Seminar on Peat Research was held in Espoo, Finland, on April 14-15, 1993. The programme consisted of technical session on Peat in Energy Production, Peat Research Programs, Peat Production and Harvesting Technology

Land Subsidence International Symposium held in Venice

Science.gov (United States)

The Third International Symposium on Land Subsidence was held March 18-25, 1984, in Venice, Italy. Sponsors were the Ground-Water Commission of the International Association of Hydrological Sciences (IAHS), the United Nations Educational, Scientific, and Cultural Organization (UNESCO), the Italian National Research Council (CNR), the Italian Regions of Veneto and Emilia-Romagna, the Italian Municipalities of Venice, Ravenna, and Modena, the Venice Province, and the European Research Office. Cosponsors included the International Association of Hydrogeologists (IAH), the International Society for Soil Mechanics and Foundation Engineering (ISSMFE), and the Association of Geoscientists for International Development (AGID).Organized within the framework of UNESCO's International Hydrological Program, the symposium brought together over 200 international interdisciplinary specialists in the problems of land subsidence due to fluid and mineral withdrawal. Because man's continuing heavy development of groundwater, gas, oil, and minerals is changing the natural regime and thus causing more and more subsiding areas in the world, there had been sufficient new land subsidence occurrence, problems, research, and remedial measures since the 1976 Second International Symposium held in Anaheim, California, to develop a most interesting program of nearly 100 papers from about 30 countries. The program consisted of papers covering case histories of fluid and mineral withdrawal, engineering theory and analysis, karst “sink-hole”-type subsidence, subsidence due to dewatering of organic deposits or due to application of water (hydrocompaction), instrumentation, legal, socioeconomic, and environmental effects of land subsidence, and remedial works.

Light element atom, molecule and radical behaviour in the divertor and edge plasma regions. Summary report of the 1. research coordination meeting

International Nuclear Information System (INIS)

Braams, B.J.

2010-01-01

The first research coordination meeting of the Coordinated Research Project (CRP) on Light Element Atom, Molecule and Radical Behaviour in the Divertor and Edge Plasma Regions was held 18-20 November 2009 at IAEA headquarters, bringing together experts representing 14 institutions. Participants summarized their recent and ongoing work pertinent to the research project. The specific objectives of the CRP and a detailed work plan were formulated. The discussions, conclusions and recommendations of the meeting are summarized in this report. (author)

Proceedings of the 18th International Conference on Engineering Design

DEFF Research Database (Denmark)

The 18th International Conference on Engineering Design, ICED11, was held August 15-18th 2011 at The Technical University of Denmark (DTU), Copenhagen. The Conference is the flagship event of the Design Society, a society dedicated to contributing to a broad and established understanding of devel......The 18th International Conference on Engineering Design, ICED11, was held August 15-18th 2011 at The Technical University of Denmark (DTU), Copenhagen. The Conference is the flagship event of the Design Society, a society dedicated to contributing to a broad and established understanding...... of development and design. The ICED series of conferences has a long tradition, which started in 1981 with the first ICED in Rome. A total of 419 papers were presented at ICED11, each double-blind reviewed by multiple reviewers. The papers included research papers and case studies on a variety of topics...... concerned with design thinking, theory, and practice, with a premium placed on evidence-based research. The papers are published in a total of ten volumes of Proceedings, in addition to electronic publication. This volume is the first of two concerned with Design Methods and Tools, and contains 45 papers...

Chronic Lymphocytic Leukemia with t(14;18(q32;q21 as a Sole Cytogenetic Abnormality

Directory of Open Access Journals (Sweden)

Ghaleb Elyamany

2014-01-01

Full Text Available Background Chronic lymphocytic leukemia (CLL is the most common leukemia in adults. The chromosomal abnormality t(14;18(q32;q21 is most commonly associated with neoplasms of a follicular center cell origin. However, t(14;18 has also been reported in rare cases of CLL. Objective We describe the clinicopathologic, immunophenotypic, conventional, and molecular cytogenetic features of two rare cases proven to be CLL morphologically and immunologically in which t(14;18 was found as the sole cytogenetic abnormality. Methods Morphologic, flow cytometric analysis and molecular cytogenetic of peripheral blood and/or bone marrow samples were analyzed. Results Cytomorphologically, the cells were small mature lymphocytes without any findings that had characteristics of follicular lymphoma (FL such as indented or clefted nuclei. Immunologic findings were characteristic of typical CLL without expression of CD10. A cytogenetic study revealed the two cases of CLL carrying t(14;18(q32;q21. Conclusion We concluded that CLL with t(14;18 is rare and should be differentiated from FL as the therapy is highly diverse between both diseases. Using immunoglobulin heavy chain gene ( IGH probes are important in the workup of patients with suspected CLL and suggest that the IGH probe should be used routinely in all CLL fluorescence in situ hybridization (FISH panels.

Occupational exposure to pesticides and occurrence of the chromosomal translocation t(14;18 among farmers in Jordan

Directory of Open Access Journals (Sweden)

Bara’a M. Qaqish

Full Text Available Background: An increased incidence of non-Hodgkin’s lymphoma (NHL has been reported in farmers and other occupational groups working with pesticides. In these individuals, an increased prevalence of the chromosomal translocation t(14;18(q32;q21, one of the most common chromosomal abnormalities in NHL, has been detected in peripheral blood lymphocytes. This translocation juxtaposes the antiapoptotic BCL2 protein to the immunoglobulin heavy chain gene locus (IGH leading to overexpression of BCL2. This causes an increase in cell survival, paving the way for malignant transformation. Aim of the study: The present study aimed to evaluate the association between the occurrence of the chromosomal translocation t(14;18 and occupational exposure to pesticides among a group of Jordanian farmers. Methods: A total of 192 male subjects including 96 agricultural workers and 96 control subjects participated in this study. BCL2-IGH t(14;18 fusions were detected by a nested polymerase chain reaction (PCR assay targeting the major breakpoint region (MBR. Results: We found that occupational exposure to pesticides in open-field farming and insecticide used on animals increased the frequency of the chromosomal translocation t(14;18. Farmers occupationally exposed to pesticides and insecticide were 13.5 times more likely to harbor t(14;18. 63.5% (61 of 96 of farmers compared to 11.5% (11 of 96 of controls carried the translocation (odds ratio: 13.5; 95% confidence interval (CI = 6.3–28.6. We ruled out the influence of possible confounding factors such as age, duration of sun exposure, alcohol intake, smoking, and use of personal protective equipment. Conclusion: Our results indicate that pesticides increased the frequency of chromosomal translocation in the 14q32 region. Accordingly, the presented data agrees with previous suggestions from the literature that pesticides might be involved in the development of NHL through the t(14;18 pathway. Keywords

Hand-held indirect calorimeter offers advantages compared with prediction equations, in a group of overweight women, to determine resting energy expenditures and estimated total energy expenditures during research screening.

Science.gov (United States)

Spears, Karen E; Kim, Hyunsook; Behall, Kay M; Conway, Joan M

2009-05-01

To compare standardized prediction equations to a hand-held indirect calorimeter in estimating resting energy and total energy requirements in overweight women. Resting energy expenditure (REE) was measured by hand-held indirect calorimeter and calculated by prediction equations Harris-Benedict, Mifflin-St Jeor, World Health Organization/Food and Agriculture Organization/United Nations University (WHO), and Dietary Reference Intakes (DRI). Physical activity level, assessed by questionnaire, was used to estimate total energy expenditure (TEE). Subjects (n=39) were female nonsmokers older than 25 years of age with body mass index more than 25. Repeated measures analysis of variance, Bland-Altman plot, and fitted regression line of difference. A difference within +/-10% of two methods indicated agreement. Significant proportional bias was present between hand-held indirect calorimeter and prediction equations for REE and TEE (Pvalues and underestimated at higher values. Mean differences (+/-standard error) for REE and TEE between hand-held indirect calorimeter and Harris-Benedict were -5.98+/-46.7 kcal/day (P=0.90) and 21.40+/-75.7 kcal/day (P=0.78); between hand-held indirect calorimeter and Mifflin-St Jeor were 69.93+/-46.7 kcal/day (P=0.14) and 116.44+/-75.9 kcal/day (P=0.13); between hand-held indirect calorimeter and WHO were -22.03+/-48.4 kcal/day (P=0.65) and -15.8+/-77.9 kcal/day (P=0.84); and between hand-held indirect calorimeter and DRI were 39.65+/-47.4 kcal/day (P=0.41) and 56.36+/-85.5 kcal/day (P=0.51). Less than 50% of predictive equation values were within +/-10% of hand-held indirect calorimeter values, indicating poor agreement. A significant discrepancy between predicted and measured energy expenditure was observed. Further evaluation of hand-held indirect calorimeter research screening is needed.

The Legacy of Manfred Held with Critique

Science.gov (United States)

2011-08-01

President Executive Vice President and Provost The report entitled “The Legacy of Manfred Held with Critique” contains the results of research...xxii THIS PAGE INTENTIONALLY LEFT BLANK xxiii EXECUTIVE SUMMARY Prof (Dr) Manfred Held...de choc des explosifs solides. Propellants and Explosives, 6, 63-66. [013] Held, M. (1987). Experiments of initiation of covered, but unconfined

Research peer exchange, 2014.

Science.gov (United States)

2017-08-01

The WSDOT Research Peer Exchange was held in Olympia, Washington on May 13 and 14, 2014 and addressed Research Program and Project Management as described in the following paragraphs: Program Management There are numerous funding programs, standing c...

A hand-held beta imaging probe for FDG.

Science.gov (United States)

Singh, Bipin; Stack, Brendan C; Thacker, Samta; Gaysinskiy, Valeriy; Bartel, Twyla; Lowe, Val; Cool, Steven; Entine, Gerald; Nagarkar, Vivek

2013-04-01

Advances in radiopharmaceuticals and clinical understanding have escalated the use of intraoperative gamma probes in surgery. However, most probes on the market are non-imaging gamma probes that suffer from the lack of ancillary information of the surveyed tissue area. We have developed a novel, hand-held digital Imaging Beta Probe™ (IBP™) to be used in surgery in conjunction with beta-emitting radiopharmaceuticals such as (18)FDG, (131)I and (32)P for real-time imaging of a surveyed area with higher spatial resolution and sensitivity and greater convenience than existing instruments. We describe the design and validation of a hand-held beta probe intended to be used as a visual mapping device to locate and confirm excision of (18)FDG-avid primary tumors and metastases in an animal model. We have demonstrated a device which can generate beta images from (18)FDG avid lesions in an animal model. It is feasible to image beta irradiation in animal models of cancer given (18)FDG. This technology may be applied to clinical mapping of tumors and/or their metastases in the operating room. Visual image depiction of malignancy may aid the surgeon in localization and excision of lesions of interest.

Long term outcome of high-risk neuroblastoma patients after immunotherapy with antibody ch14.18 or oral metronomic chemotherapy

International Nuclear Information System (INIS)

Simon, Thorsten; Hero, Barbara; Faldum, Andreas; Handgretinger, Rupert; Schrappe, Martin; Klingebiel, Thomas; Berthold, Frank

2011-01-01

The treatment of high-risk neuroblastoma patients consists of multimodal induction therapy to achieve remission followed by consolidation therapy to prevent relapses. However, the type of consolidation therapy is still discussed controversial. We applied metronomic chemotherapy in the prospective NB90 trial and monoclonal anti-GD2-antibody (MAB) ch14.18 in the NB97 trial. Here, we present the long term outcome data of the patient cohort. A total of 334 stage 4 neuroblastoma patients one year or older were included. All patients successfully completed the induction therapy. In the NB90 trial, 99 patients received at least one cycle of the oral maintenance chemotherapy (NB90 MT, 12 alternating cycles of oral melphalan/etoposide and vincristine/cyclophosphamide). In the NB97 trial, 166 patients commenced the MAB ch14.18 consolidation therapy (six cycles over 12 months). Patients who received no maintenance therapy according to the NB90 protocol or by refusal in NB97 (n = 69) served as controls. The median observation time was 11.11 years. The nine-year event-free survival rates were 41 ± 4%, 31 ± 5%, and 32 ± 6% for MAB ch14.18, NB90 MT, and no consolidation, respectively (p = 0.098). In contrast to earlier reports, MAB ch14.18 treatment improved the long-term outcome compared to no additional therapy (p = 0.038). The overall survival was better in the MAB ch14.18-treated group (9-y-OS 46 ± 4%) compared to NB90 MT (34 ± 5%, p = 0.026) and to no consolidation (35 ± 6%, p = 0.019). Multivariable Cox regression analysis revealed ch14.18 consolidation to improve outcome compared to no consolidation, however, no difference between NB90 MT and MAB ch14.18-treated patients was found. Follow-up analysis of the patient cohort indicated that immunotherapy with MAB ch14.18 may prevent late relapses. Finally, metronomic oral maintenance chemotherapy also appeared effective

Long term outcome of high-risk neuroblastoma patients after immunotherapy with antibody ch14.18 or oral metronomic chemotherapy

Directory of Open Access Journals (Sweden)

Schrappe Martin

2011-01-01

Full Text Available Abstract Background The treatment of high-risk neuroblastoma patients consists of multimodal induction therapy to achieve remission followed by consolidation therapy to prevent relapses. However, the type of consolidation therapy is still discussed controversial. We applied metronomic chemotherapy in the prospective NB90 trial and monoclonal anti-GD2-antibody (MAB ch14.18 in the NB97 trial. Here, we present the long term outcome data of the patient cohort. Methods A total of 334 stage 4 neuroblastoma patients one year or older were included. All patients successfully completed the induction therapy. In the NB90 trial, 99 patients received at least one cycle of the oral maintenance chemotherapy (NB90 MT, 12 alternating cycles of oral melphalan/etoposide and vincristine/cyclophosphamide. In the NB97 trial, 166 patients commenced the MAB ch14.18 consolidation therapy (six cycles over 12 months. Patients who received no maintenance therapy according to the NB90 protocol or by refusal in NB97 (n = 69 served as controls. Results The median observation time was 11.11 years. The nine-year event-free survival rates were 41 ± 4%, 31 ± 5%, and 32 ± 6% for MAB ch14.18, NB90 MT, and no consolidation, respectively (p = 0.098. In contrast to earlier reports, MAB ch14.18 treatment improved the long-term outcome compared to no additional therapy (p = 0.038. The overall survival was better in the MAB ch14.18-treated group (9-y-OS 46 ± 4% compared to NB90 MT (34 ± 5%, p = 0.026 and to no consolidation (35 ± 6%, p = 0.019. Multivariable Cox regression analysis revealed ch14.18 consolidation to improve outcome compared to no consolidation, however, no difference between NB90 MT and MAB ch14.18-treated patients was found. Conclusions Follow-up analysis of the patient cohort indicated that immunotherapy with MAB ch14.18 may prevent late relapses. Finally, metronomic oral maintenance chemotherapy also appeared effective.

Support for GCTE-LUCC open Science Conference on global change. Final report for period September 15, 1997, - September 14, 1998

International Nuclear Information System (INIS)

Pitelka, L.F.

1999-01-01

The Global Change and Terrestrial Ecosystems (GCTE) core project of the International Geosphere-Biosphere Program (IGBP) and the Land-Use/Cover Change (LUCC) core project of IGBP and the International Human Dimensions Program (IHDP) held a major open Science Conference in Barcelona, Spain, on 14-18 March 1998. At the Conference, scientists presented the most recent research findings from these two international projects, explored emerging cross-cutting linkages between the projects, and highlighted the importance of the regional approach to global change research. This grant from the U.S. Department of Energy, Office of Biological and Environmental Research, provided support for the Conference by contributing to the production of conference literature and by supporting the participation of U.S. scientists in the Conference

S-factor of 14 N (α, γ)18 F reaction at low-energies

Science.gov (United States)

Khalili, H.

2018-06-01

The astrophysical S-factor of the 14 N (α, γ)18 F reaction has been studied at range of bombarding energy 1-1.30 MeV. The 14 N (α, γ)18 F process is important in low energy astrophysics so that a possible source of energy in massive stars which have spent their hydrogen cycle. Using the Wood-saxon potential model, we have been calculated non resonances the astrophysical S-factors for the E 2 transition and our results for Eα = 0.0 MeV is S ≈ 0.5 MeV.b where from experimental is measured to Eα = 0.0 is S ≈ o . 7 MeV.b (Couch et al., 1971) that in comparison with our data good agreement is achieved for the astrophysical S-factor of this process.

14 CFR 141.18 - Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances. 141.18 Section 141.18 Aeronautics and Space FEDERAL AVIATION... General § 141.18 Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances...

Hand-held medical robots.

Science.gov (United States)

Payne, Christopher J; Yang, Guang-Zhong

2014-08-01

Medical robots have evolved from autonomous systems to tele-operated platforms and mechanically-grounded, cooperatively-controlled robots. Whilst these approaches have seen both commercial and clinical success, uptake of these robots remains moderate because of their high cost, large physical footprint and long setup times. More recently, researchers have moved toward developing hand-held robots that are completely ungrounded and manipulated by surgeons in free space, in a similar manner to how conventional instruments are handled. These devices provide specific functions that assist the surgeon in accomplishing tasks that are otherwise challenging with manual manipulation. Hand-held robots have the advantages of being compact and easily integrated into the normal surgical workflow since there is typically little or no setup time. Hand-held devices can also have a significantly reduced cost to healthcare providers as they do not necessitate the complex, multi degree-of-freedom linkages that grounded robots require. However, the development of such devices is faced with many technical challenges, including miniaturization, cost and sterility, control stability, inertial and gravity compensation and robust instrument tracking. This review presents the emerging technical trends in hand-held medical robots and future development opportunities for promoting their wider clinical uptake.

CT-guided diagnostic interventions for classification of focal hepatic lesions: A comparison of 14 G- and 18 G-large bore cutting needles; CT-gesteuerte perkutane Biopsien zur Klassifizierung von fokalen Leberlaesionen: Vergleich zwischen 14 G- und 18 G-Stanzbiopsienadeln

Energy Technology Data Exchange (ETDEWEB)

Haage, P.; Piroth, W.; Staatz, G.; Adam, G.; Guenther, R.W. [Klinik fuer Radiologische Diagnostik, Universitaetsklinikum der RWTH Aachen (Germany)

1999-07-01

Purpose: Analysis and comparison of CT-guided 14- and 18-gauge cutting needle biopsies to accurately assess focal liver disease. Methods: The data of 272 CT-guided biopsies in 268 patients were evaluated retrospectively with regard to sensitivity, specificity and complication rate of the chosen needle caliber in differentiating between benign and malignant disease as well as in the ability to determine specific cell types in the various disorders. A 14-gauge (G) needle was used in 101 (37.1%) cases, in 18-g needle biopsy was performed in 171 (62.9%) cases. The Fisher exact test was employed for statistical analysis. Results: Cutting needle biopsy yielded sufficient histologic material in 267 of 272 (98.2%) cases. Correct diagnosis of malignancy was established in 178 of 191 (93.2%) lesions, 73 of 76 (96.1%) disorders were accurately defined as benign, resulting in an overall value of 94.0% (251 of 267). Of these 251 biopsies a definite histological diagnosis could be determined in 90.6% of the cases employing a 14 G needle and in 90.3% using an 18-g needle. The sensitivity, specificity and rate of complications were 94.8%, 92.0%%, 3.0% for the 14-g needle and 92.7%, 97.6%, 0.6% for the 18-g needle, respectively. There were no statistically significant differences with regard to the needle size. Conclusions: CT-guided biopsy of hepatic lesions with the 18-g biopsy needle is of equivalent diagnostic accuracy when compared with the 14-g needle. (orig.) [Deutsch] Ziel: Analyse und Vergleich CT-gesteuerter Fein- und Grobstanzbiopsien zur definitiven Abklaerung unklarer fokaler Leberveraenderungen. Methoden: Die Daten von insgesamt 272 CT-gefuehrten Punktionen an 268 Patienten wurden retrospektiv hinsichtlich Sensitivitaet, Spezifitaet und Komplikationsrate zur Dignitaetsbestimmung und Faehigkeit zur artdiagnostischen Einordnung unter Beruecksichtigung der Groesse der gewaehlten Punktionsnadel ueberprueft und ausgewertet. In 101 (37,1%) Faellen wurde eine 14 Gauge (G

Proceedings of the sixth technical committee meeting organized by the IAEA and held in Vienna, Austria, 8-11 June 1987

International Nuclear Information System (INIS)

1987-01-01

The Technical Committee on Thermal Reactor Safety Research held its sixth meeting from 8-11 June 1987 at the Agency's Headquarters in Vienna. It was attended by 25 participants representing 18 countries and 2 international organizations. With respect to exchange on national research activities the committee members presented their most recent achievements in the area of nuclear safety research. A separate abstract was prepared for each of their presentations. Refs, figs and tabs

Religion, sex and politics: Scripting connections in Romans 1:18–32 and Wisdom 14:12–14

Directory of Open Access Journals (Sweden)

Jeremy Punt

2017-08-01

Full Text Available Ancient people envisaged a strong link between what was deemed transgressive religious activities and objectionable sexual practices. Moreover, sexual behaviour considered aberrant was deemed to upset political boundaries which should protect civic and national stability, especially when this behaviour was suspected of effeminacy. Such thinking appears to inform both Romans 1:18–32 and Wisdom of Solomon 14:12–14. Focussing on two passages from these documents, the links between religion, sexual behaviour and politics in the context of the 1st-century Roman Empire are investigated, tracing underlying ideological intersections, connections and divergences.

The Maritime Environment - International Conference and Exhibition on Ballast Water, Waste Water and Sewage Treatment on Ships and in Ports Held in Bremerhaven, Germany on 12-14 September 2001. Conference Proceedings

National Research Council Canada - National Science Library

2001-01-01

The Maritime International Conference on Ballast Water, Waste Water and Sewage Treatment on Ships and in Ports held in Bremerhaven, Germany on 12-14 September 2001 was cosponsored by Deerberg-Systems...

18th and 19th Workshop on Sustained Simulation Performance

CERN Document Server

Bez, Wolfgang; Focht, Erich; Kobayashi, Hiroaki; Patel, Nisarg

2015-01-01

This book presents the state of the art in high-performance computing and simulation on modern supercomputer architectures. It covers trends in hardware and software development in general and the future of high-performance systems and heterogeneous architectures in particular. The application-related contributions cover computational fluid dynamics, material science, medical applications and climate research; innovative fields such as coupled multi-physics and multi-scale simulations are highlighted. All papers were chosen from presentations given at the 18th Workshop on Sustained Simulation Performance held at the HLRS, University of Stuttgart, Germany in October 2013 and subsequent Workshop of the same name held at Tohoku University in March 2014.  

V International Golden Horde Forum (Kazan, Russian Federation, March 15–18, 2017

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E.G. Sayfetdinova

2017-09-01

Full Text Available M.A.Usmanov Center for Research on the Golden Horde and Tatar Khanates of Sh.Marjani Institute of History of Tatarstan Academy of Sciences became the organizer of a major international academic event aimed at highlighting the source study of the history of the Golden Horde and the Turkic-Tatar khanates. The fifth international Golden Horde Forum was held in Kazan on March 15–18, 2017, which was attended by researchers from 18 countries: Russia, USA, France, England, Mongolia, Finland, Serbia, Kazakhstan, Ukraine, etc. Two international conferences and two round tables were held in the framework of the Forum. The first research conference “Source Study of the History of the Golden Horde and Tatar Khanates: Textology, Translations, Interpretations” wad dedicated to important issues of source study of the history of the Golden Horde and the Turkic-Tatar khanates. The second research conference was dedicated to the topic “Coinage and Money Circulation in the Golden Horde and Turkic-Tatar Khanates in the Light of Source Studies”. The round table “Ecological and Epidemic Factor in Medieval Eurasia” was the third research event in the framework of the Forum. The round table “The Golden Horde on the Great Silk Road” was organized on March 16, 2017 in conjunction with the Council of Muftis of the Russian Federation. When summing up the results of the Forum, participants noted that all events were held at a high scholarly level, contributed to the strengthening of international academic relations and made it possible to make substantial progress in solving actual research problems and to outline the prospects for further research.

18 CFR 1312.14 - Determination of archaeological or commercial value and cost of restoration and repair.

Science.gov (United States)

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Determination of archaeological or commercial value and cost of restoration and repair. 1312.14 Section 1312.14 Conservation of... part shall be its fair market value. Where the violation has resulted in damage to the archaeological...

High-Precision Half-Life Measurements for the Superallowed Fermi β+ Emitters 14O and 18Ne

Science.gov (United States)

Laffoley, A. T.; Andreoiu, C.; Austin, R. A. E.; Ball, G. C.; Bender, P. C.; Bidaman, H.; Bildstein, V.; Blank, B.; Bouzomita, H.; Cross, D. S.; Deng, G.; Diaz Varela, A.; Dunlop, M. R.; Dunlop, R.; Finlay, P.; Garnsworthy, A. B.; Garrett, P.; Giovinazzo, J.; Grinyer, G. F.; Grinyer, J.; Hadinia, B.; Jamieson, D. S.; Jigmeddorj, B.; Ketelhut, S.; Kisliuk, D.; Leach, K. G.; Leslie, J. R.; MacLean, A.; Miller, D.; Mills, B.; Moukaddam, M.; Radich, A. J.; Rajabali, M. M.; Rand, E. T.; Svensson, C. E.; Tardiff, E.; Thomas, J. C.; Turko, J.; Voss, P.; Unsworth, C.

High-precision half-life measurements, at the level of ±0.04%, for the superallowed Fermi emitters 14O and 18Ne have been performed at TRIUMF's Isotope Separator and Accelerator facility. Using 3 independent detector systems, a gas-proportional counter, a fast plastic scintillator, and a high-purity germanium array, a series of direct β and γ counting measurements were performed for each of the isotopes. In the case of 14O, these measurements were made to help resolve an existing discrepancy between detection methods, whereas for 18Ne the half-life precision has been improved in anticipation of forthcoming high-precision branching ratio measurements.

The PHARMS (Patient Held Active Record of Medication Status) feasibility study: a research proposal.

LENUS (Irish Health Repository)

Walsh, Elaine

2018-01-08

Medication errors are a major source of preventable morbidity, mortality and cost and many occur at the times of hospital admission and discharge. Novel interventions (such as new methods of recording medication information and conducting medication reconciliation) are required to facilitate accurate transfer of medication information. With existing evidence supporting the use of information technology and the patient representing the one constant in the care process, an electronic patient held medication record may provide a solution. This study will assess the feasibility of introducing a patient held electronic medication record in primary and secondary care using the Consolidated Framework for Implementation Research (CFIR).This feasibility study is a mixed method study of community dwelling older adult patients admitted to an urban secondary care facility comprising a non-randomised intervention and qualitative interviews with key stakeholders. Outcomes of interest include clinical outcomes and process evaluation.This study will yield insights pertaining to feasibility, acceptability and participation for a more definitive evaluation of the intervention. The study also has the potential to contribute to knowledge of implementation of technology in a healthcare context and to the broader area of implementation science.

TRIGA 14 MW Research Reactor Status and Utilization

International Nuclear Information System (INIS)

Barbos, D.; Ciocanescu, M.; Paunoiu, C.

2016-01-01

Institute for Nuclear Research is the owner of the largest family TRIGA research reactor, TRIGA14 MW research reactor. TRIGA14 MW reactor was designed to be operated with HEU nuclear fuel but now the reactor core was fully converted to LEU nuclear fuel. The full conversion of the core was a necessary step to ensure the continuous operation of the reactor. The core conversion took place gradually, using fuel manufactured in different batches by two qualified suppliers based on the same well qualified technology for TRIGA fuel, including some variability which might lead to a peculiar behaviour under specific conditions of reactor utilization. After the completion of the conversion a modernization program for the reactor systems was initiated in order to achieve two main objectives: safe operation of the reactor and reactor utilization in a competitive environment to satisfy the current and future demands and requirements. The 14 MW TRIGA research reactor operated by the Institute for Nuclear Research in Pitesti, Romania, is a relatively new reactor, commissioned 37 years ago. It is expected to operate for another 15-20 years, sustaining new fuel and testing of materials for future generations of power reactors, supporting radioisotopes production through the development of more efficient new technologies, sustaining research or enhanced safety, extended burn up and verification of new developments concerning nuclear power plants life extension, to sustain neutron application in physics research, thus becoming a centre for instruction and training in the near future. A main objective of the TRIGA14MW research reactor is the testing of nuclear fuel and nuclear material. The TRIGA 14 MW reactor is used for medical and industrial radioisotopes production ( 131 I, 125 I, 192 Ir etc.) and a method for 99 Mo- 99 Tc production from fission is under development. For nuclear materials properties investigation, neutron radiography methods have been developed in the INR. The

Theoretical study of isoelectronic SinM clusters (M=Sc-,Ti,V+; n=14-18)

DEFF Research Database (Denmark)

Torres, M. B.; Fernandez Sanchez, Eva; Balbás, L. C.

2007-01-01

We study, from first-principles quantum mechanical calculations, the structural and electronic properties of several low-lying energy equilibrium structures of isoelectronic SinM clusters (M=Sc-,Ti,V+) for n=14-18. The main result is that those clusters with n=16 are more stable than its neighbors...... of the spherical potential model). The structures of the two lowest energy isomers of Si16M are nearly degenerate, and consist of the Frank-Kasper polyhedron and a distortion of that polyhedron. The first structure is the ground state for M=V+, and the second is the ground state for Ti and Sc-. For the lowest...... energy isomers of clusters SinM with n=14-18, we analyze the changes with size n, and impurity M of several quantities: binding energy, second difference of total energy, HOMO-LUMO gap, adiabatic electron affinity, addition energy of a Si atom, and addition energy of an M impurity to a pure Si-n cluster...

Planktonic primary production in estuaries: a comparison of the 14C, O2 and 18O methods

NARCIS (Netherlands)

Gazeau, F.P.H.; Middelburg, J.J.; Loijens, M.; Vanderborght, J.P.; Pizay, M-D.; Gattuso, J.P.

2007-01-01

Rates of primary production were measured in 2 estuaries (Randers Fjord, Denmark, and the Scheldt estuary, Belgium/The Netherlands) using 3 different incubation methods: (1) the oxygen light-dark method (O2-LD), (2) 14C incorporation and (3) 18O labeling. Estimates based on the 14C incorporation

10 μm High-resolution spectrum of trans -acrolein: Rotational analysis of the ν 11 , ν 16 , ν 14 and ν 16 + ν 18 - ν 18 bands

Science.gov (United States)

Xu, Li-Hong; Jiang, Xingjie; Shi, Hongyu; Lees, R. M.; McKellar, A. R. W.; Tokaryk, D. W.; Appadoo, D. R. T.

2011-07-01

High-resolution Fourier transform spectra of trans-acrolein, H 2C dbnd C(H) sbnd C(H) dbnd O, have been recorded in the 10 μm region at both room and cooled temperatures on the modified Bomem DA3.002 at the National Research Council of Canada and the Bruker IFS 125HR spectrometer at the far infrared beam line of the Canadian Light Source in Saskatoon. Vibrational fundamentals analyzed so far include the ν11, ν16 and ν14 bands centered at 911.3, 958.7 and 992.7 cm -1 corresponding respectively to the A' in-plane dbnd CH 2-rocking mode, the A″ out-of-plane dbnd CH 2-wagging mode, and the A″ wagging mode highly mixed between the ⩾C sbnd H vinyl and ⩾C sbnd H formyl groups [Vibrational mode descriptions are based on Y.N. Panchenko, P. Pulay, F. Török, J. Mol. Spectrosc. 34 (1976) 283-289.] As well, the ν16 + ν18 - ν18 hot band centred at 957.6 cm -1 has been analyzed, where ν18 is the low-frequency (157.9 cm -1) A″ ⩾C sbnd C ⪕ torsional mode. The ν11 band is a/ b type while the ν16, ν14 and ν16 + ν18 - ν18 bands are c-type. The assigned transitions of each band have been fitted to a Watson asymmetric rotor Hamiltonian, with ground state parameters fixed to values obtained from rotational analyses in the literature. As well, a combined 3-state fit for ν11, ν16 and ν14 was carried out including Coriolis and Z1 constants which account for J and Δ K interactions. Transition dipole moments have been calculated for each of the fundamentals using the ab initio B3LYP method and 6-311++G ∗∗ basis set. For the A' vibrational modes, we have also evaluated transition dipole a- and b-components in the principal axis system from vibrational displacements and dipole moment derivatives. Our ab initio results predict that the ν11 in-plane dbnd CH 2 rocking mode has an a-type transition strength about three times greater than the b-type, which is consistent with our observations. Our ab initio force field analysis gives vibrational mode

The prevalence of malocclusion among 14-18 years old students in Shiraz

Directory of Open Access Journals (Sweden)

Hamidreza Arabiun

2014-06-01

Full Text Available BACKGROUND AND AIM: Malocclusions are major traits whose prevalence should be noticed, by gender, among high school students to program oral health status in a society and clarify the needs and demands of this orthodontic field. METHODS: In a cross-sectional population-based study, using a stratified random cluster sampling design, a sample of 1338 students of Shiraz, aged 14-18 years from 15 high schools, located in four different regions of Shiraz was obtained and evaluated clinically for malocclusion traits. Using tongue blades, researchers studied the students under normal room illumination conditions. RESULTS: The overall prevalence of malocclusion was 23.70%. Angle’s classes I, II, and III malocclusion were observed in 12.78%, 9.94%, and 0.97% of the samples, respectively. There was no statistically significant difference in the overall prevalence of malocclusion between sexes. Other malocclusion traits evaluated were edge-to-edge occlusion (4.78%, crossbite (1.93%, and open bite (1.19%. CONCLUSION: The results of this study showed a high prevalence of malocclusion class I as well as an edge to edge malocclusion trait. Considering the findings, health care officials are expected to pay more attention to oral health fields.

Proceedings of the workshop of three large tokamak cooperation on energy confinement scaling under intensive auxiliary heating, May 18 ∼ 20, 1992, Naka

International Nuclear Information System (INIS)

1992-09-01

The workshop of three large tokamak cooperation W22 on 'Energy confinement scaling under intensive auxiliary heating' was held 18-20 May, 1992, at Naka Fusion Research Establishment. This proceedings compiles 14 synopses of contributions (5 from JET, 4 from JT-60, 3 from TFTR, and 1 each from DIII-D JFT-2M) and the summary of the workshop. Topic sections are ; (i) L-mode confinement and scaling, (ii) Confinement at high β P regimes, Supershots, High poloidal beta enhanced confinement mode etc., (iii) Confinement at various H-mode regimes and scaling (including the VH-mode), (iv) Characteristic time scales for present tokamak regimes, and (v) Theoretical comparison with experimental data. (author)

Absolute quantification of regional cerebral glucose utilization in mice by 18F-FDG small animal PET scanning and 2-14C-DG autoradiography.

Science.gov (United States)

Toyama, Hiroshi; Ichise, Masanori; Liow, Jeih-San; Modell, Kendra J; Vines, Douglass C; Esaki, Takanori; Cook, Michelle; Seidel, Jurgen; Sokoloff, Louis; Green, Michael V; Innis, Robert B

2004-08-01

The purpose of this study was to evaluate the feasibility of absolute quantification of regional cerebral glucose utilization (rCMR(glc)) in mice by use of (18)F-FDG and a small animal PET scanner. rCMR(glc) determined with (18)F-FDG PET was compared with values determined simultaneously by the autoradiographic 2-(14)C-DG method. In addition, we compared the rCMR(glc) values under isoflurane, ketamine and xylazine anesthesia, and awake states. Immediately after injection of (18)F-FDG and 2-(14)C-DG into mice, timed arterial samples were drawn over 45 min to determine the time courses of (18)F-FDG and 2-(14)C-DG. Animals were euthanized at 45 min and their brain was imaged with the PET scanner. The brains were then processed for 2-(14)C-DG autoradiography. Regions of interest were manually placed over cortical regions on corresponding coronal (18)F-FDG PET and 2-(14)C-DG autoradiographic images. rCMR(glc) values were calculated for both tracers by the autoradiographic 2-(14)C-DG method with modifications for the different rate and lumped constants for the 2 tracers. Average rCMR(glc) values in cerebral cortex with (18)F-FDG PET under normoglycemic conditions (isoflurane and awake) were generally lower (by 8.3%) but strongly correlated with those of 2-(14)C-DG (r(2) = 0.95). On the other hand, under hyperglycemic conditions (ketamine/xylazine) average cortical rCMR(glc) values with (18)F-FDG PET were higher (by 17.3%) than those with 2-(14)C-DG. Values for rCMR(glc) and uptake (percentage injected dose per gram [%ID/g]) with (18)F-FDG PET were significantly lower under both isoflurane and ketamine/xylazine anesthesia than in the awake mice. However, the reductions of rCMR(glc) were markedly greater under isoflurane (by 57%) than under ketamine and xylazine (by 19%), whereas more marked reductions of %ID/g were observed with ketamine/xylazine (by 54%) than with isoflurane (by 37%). These reverse differences between isoflurane and ketamine/xylazine may be due to

14th International Conference on Particle Induced X-ray Emission ("PIXE 2015")

Science.gov (United States)

Przybyłowicz, Wojciech Józef; Pineda-Vargas, Carlos

2015-11-01

This special issue of Nuclear Instruments and Methods in Physics Research B contains the proceedings of the 14th International Conference on Particle Induced X-ray Emission ("PIXE 2015") that was held in Somerset West (South Africa) from 25th February to 3rd March 2015.

Recent research in DNA repair, mutation and recombination: a report of the DNA Repair Network meeting, held at City University, London on 18 December 1995.

Science.gov (United States)

Jones, N J; Strike, P

1996-09-02

The now traditional one day Christmas DNA Repair meeting was held at City University, London for the third year in succession. With over 130 participants and a programme consisting of a total of 24 pre-offered presentations the meeting reached record dimensions. Attendees were from 24 institutions throughout the United Kingdom, and with several distinct research groups contained within the large contingents from the ICRF Clare Hall Laboratories and the MRC Cell Mutation Unit in Brighton, this indicates the increasing interest and depth of UK research in DNA repair. One slight disappointment of the meeting was the fall in the numbers of non-UK participants. Although the meeting in 1994 (Strike, 1995) saw an increase in presentations from Continental Europe (six countries including France, Germany. The Netherlands and Switzerland), the trend did not continue this year, with only Denmark being represented. The 24 contributors consisted of approximately equal numbers of postgraduate students, postdoctoral researchers and more "established' scientists reflecting the continuing policy of encouraging younger members of the repair community to present their work. The mix of presenters was particularly well illustrated by two excellent and consecutive talks by Professor Bryn Bridges (MRC Cell Mutation Unit) and Alison Mitchell, a postgraduate student in Stephen West's laboratory (ICRF, Clare Hall). The organisms under study were as equally disparate and included Archaebacteria, Escherichia coli. Saccharomyces cerevisiae, Schizosaccharomyces pombe, Aspergillus, mice and men. The range of topics was also varied and included bacterial mutagenesis, NMR studies of Ada protein, preferential DNA repair, cell cycle checkpoint genes, reconstitution of nucleotide excision repair and V(D)J recombination in vitro, creation of repair deficient transgenic mice and mismatch defects in human cells. The result was a very successful meeting which was characterized by the consistently high

14th International Conference on Intelligent Autonomous Systems

CERN Document Server

Hosoda, Koh; Menegatti, Emanuele; Shimizu, Masahiro; Wang, Hesheng

2017-01-01

This book describes the latest research advances, innovations, and visions in the field of robotics as presented by leading researchers, engineers, and practitioners from around the world at the 14th International Conference on Intelligent Autonomous Systems (IAS-14), held in Shanghai, China in July 2016. The contributions amply demonstrate that robots, machines and systems are rapidly achieving intelligence and autonomy, attaining more and more capabilities such as mobility and manipulation, sensing and perception, reasoning, and decision-making. They cover a wide range of research results and applications, and particular attention is paid to the emerging role of autonomous robots and intelligent systems in industrial production, which reflects their maturity and robustness. The contributions were selected by means of a rigorous peer-review process and highlight many exciting and visionary ideas that will further galvanize the research community and spur novel research directions. The series of biennial IAS ...

Proceedings of the seminar on optimization technology of the use of G.A. Siwabessy Research Reactor

International Nuclear Information System (INIS)

1999-01-01

Seminar on optimization technology of the use of G.A. Siwabessy research reactor was held on March 16, 1999 at the Multipurpose Reactor Center, Serpong, Indonesia. During the seminar, have presented 14 papers about activities or researches on reactor operation technology, use of G.A. Siwabessy research reactor, engineering and nuclear installation development, maintenance and quality assurances. The seminar was held as a tool for developing non-researcher functional workers

Proceedings of the seminar on optimization technology of the use of G.A. Siwabessy Research Reactor

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-07-01

Seminar on optimization technology of the use of G.A. Siwabessy research reactor was held on March 16, 1999 at the Multipurpose Reactor Center, Serpong, Indonesia. During the seminar, have presented 14 papers about activities or researches on reactor operation technology, use of G.A. Siwabessy research reactor, engineering and nuclear installation development, maintenance and quality assurances. The seminar was held as a tool for developing non-researcher functional workers.

T(14;18) is Not Associated with Mixed Cryoglobulinemia or with Clonal B Cell Expansion in Egyptian Patients with Hepatitis C Virus Infection

International Nuclear Information System (INIS)

ABBAS, O.M.; OMAR, N.A.; HASSAN, Z.K.

2008-01-01

Background/Aim: The mechanisms of B-cell lymphoproliferative disorders in chronic hepatitis C virus (Hv) infection are unclear. An increased prevalence of circulating monoclonal B-cells and t(14;18) has been reported. Geographic heterogeneity of prevalence of t(14;18) has been shown to exist. We investigated the prevalence of t(14;18) and B-cell clonality as possible mechanisms of lymphoma genesis in chronic HCV patients, in whom cryoglobulinemia status was previously detected. Methods: A cohort of 111 patients was studied, including 87 patients with chronic HCV disease (18 cryoglobulinemic and 69 non- cryoglobulinemic); 24 HCV negative, cryoglobulin negative patients with other nonimmune chronic liver diseases were enrolled as controls. The t(14;18) and IgH rearrangement (as a marker of B cell clonality) were detected by the polymerase chain reaction. Results: t(14;18) was detected in 27.6% of HCV patients and in none of the controls. Detection rates were comparable in both cryoglobulin-positive and negative groups (22.2% and 29%, respectively), p=0.769. IgH rearrangement was detected in 39.1% of HCV patients and in none of the controls. The cryo globulin-positive group showed significantly higher prevalence of IgH rearrangement compared to the cryoglobulin-negative group (61.1% and 33.3%, respectively), p=0.03, OR=3.13 and 95% CI=1.07-9.17. t(14;18) and monoclonal IgH rearrangement detection rates were not associated with each other, p=0.467. Conclusion: t(14;18) is uncommon in HCV-mixed cryogoblulinemia Egyptian patients; it does not seem to play a role in HCV-associated MC and lymphoma genesis in our geographical area. HCV may play a role in mixed cryogoblulinemia and lymphoma genesis, probably by inducing clonal B-cell expansions.

A Pilot Trial of Humanized Anti-GD2 Monoclonal Antibody (hu14.18K322A) with Chemotherapy and Natural Killer Cells in Children with Recurrent/Refractory Neuroblastoma.

Science.gov (United States)

Federico, Sara M; McCarville, M Beth; Shulkin, Barry L; Sondel, Paul M; Hank, Jacquelyn A; Hutson, Paul; Meagher, Michael; Shafer, Aaron; Ng, Catherine Y; Leung, Wing; Janssen, William E; Wu, Jianrong; Mao, Shenghua; Brennan, Rachel C; Santana, Victor M; Pappo, Alberto S; Furman, Wayne L

2017-11-01

Purpose: Anti-GD2 mAbs, acting via antibody-dependent cell-mediated cytotoxicity, may enhance the effects of chemotherapy. This pilot trial investigated a fixed dose of a unique anti-GD2 mAb, hu14.18K322A, combined with chemotherapy, cytokines, and haploidentical natural killer (NK) cells. Experimental Design: Children with recurrent/refractory neuroblastoma received up to six courses of hu14.18K322A (40 mg/m 2 /dose, days 2-5), GM-CSF, and IL2 with chemotherapy: cyclophosphamide/topotecan (courses 1,2), irinotecan/temozolomide (courses 3,4), and ifosfamide/carboplatin/etoposide (courses 5,6). Parentally derived NK cells were administered with courses 2, 4, and 6. Serum for pharmacokinetic studies of hu14.18K322A, soluble IL2 receptor alpha (sIL2Rα) levels, and human antihuman antibodies (HAHA) were obtained. Results: Thirteen heavily pretreated patients (9 with prior anti-GD2 therapy) completed 65 courses. One patient developed an unacceptable toxicity (grade 4 thrombocytopenia >35 days). Four patients discontinued treatment for adverse events (hu14.18K322A allergic reaction, viral infection, surgical death, second malignancy). Common toxicities included grade 3/4 myelosuppression (13/13 patients) and grade 1/2 pain (13/13 patients). Eleven patients received 29 NK-cell infusions. The response rate was 61.5% (4 complete responses, 1 very good partial response, 3 partial responses) and five had stable disease. The median time to progression was 274 days (range, 239-568 days); 10 of 13 patients (77%) survived 1 year. Hu14.18K322A pharmacokinetics was not affected by chemotherapy or HAHA. All patients had increased sIL2Rα levels, indicating immune activation. Conclusions: Chemotherapy plus hu14.18K322A, cytokines, and NK cells is feasible and resulted in clinically meaningful responses in patients with refractory/recurrent neuroblastoma. Further studies of this approach are warranted in patients with relapsed and newly diagnosed neuroblastoma. Clin Cancer Res; 23

The image of mathematics held by Irish post-primary students

Science.gov (United States)

Lane, Ciara; Stynes, Martin; O'Donoghue, John

2014-08-01

The image of mathematics held by Irish post-primary students was examined and a model for the image found was constructed. Initially, a definition for 'image of mathematics' was adopted with image of mathematics hypothesized as comprising attitudes, beliefs, self-concept, motivation, emotions and past experiences of mathematics. Research focused on students studying ordinary level mathematics for the Irish Leaving Certificate examination - the final examination for students in second-level or post-primary education. Students were aged between 15 and 18 years. A questionnaire was constructed with both quantitative and qualitative aspects. The questionnaire survey was completed by 356 post-primary students. Responses were analysed quantitatively using Statistical Package for the Social Sciences (SPSS) and qualitatively using the constant comparative method of analysis and by reviewing individual responses. Findings provide an insight into Irish post-primary students' images of mathematics and offer a means for constructing a theoretical model of image of mathematics which could be beneficial for future research.

Jedenáctá mezinárodní konference o barokní hudbě, The Royal Northern College of Music, Manchester 14.–18. 7. 2004

Czech Academy of Sciences Publication Activity Database

Kapsa, Václav

2004-01-01

Roč. 41, 3-4 (2004), s. 399-402 ISSN 0018-7003. [Biennial International Conference on Baroque Music /11./. Manchester, 04.07.14-04.07.18] R&D Projects: GA ČR(CZ) GD408/03/H049 Institutional research plan: CEZ:AV0Z9058907 Keywords : baroque music * conference * report Subject RIV: AL - Art, Architecture, Cultural Heritage

Research on 18th Century Music in Poland. An Introduction

Directory of Open Access Journals (Sweden)

Paczkowski Szymon

2016-12-01

Full Text Available Research on 18th-century music has been one of the key areas of interest for musicologists ever since the beginnings of musicological studies in Poland. It initially developed along two distinct lines: general music history (with publications mostly in foreign languages and local history (mostly in Polish. In the last three decades the dominant tendency among Polish researchers has been, however, to relate problems of 18th-century Polish musical culture to the political history of the Polish-Lithuanian Commonwealth and more generally – to the political history of Central Europe at large. The most important subjects taken up in research on 18th-century music include: the musical cultures of the royal court in 18th-century Warsaw (primarily in the works of Alina Żórawska-Witkowska as well as Polish aristocratic residences (e.g. studies by Szymon Paczkowski and Irena Bieńkowska, the ecclesiastical and monastic circles (publications by Alina Mądry, Paweł Podejko, Remigiusz Pośpiech and Tomasz Jeż; problems of musical style (texts by Szymon Paczkowski; research on sources containing music by European composers (e.g. by Johann Adolf Hasse; the musical culture of cities (of Gdańsk, first and foremost; studies concerning the transfer of music and music-related materials, the musical centres and peripheries, etc.

Production Support Flight Control Computers: Research Capability for F/A-18 Aircraft at Dryden Flight Research Center

Science.gov (United States)

Carter, John F.

1997-01-01

NASA Dryden Flight Research Center (DFRC) is working with the United States Navy to complete ground testing and initiate flight testing of a modified set of F/A-18 flight control computers. The Production Support Flight Control Computers (PSFCC) can give any fleet F/A-18 airplane an in-flight, pilot-selectable research control law capability. NASA DFRC can efficiently flight test the PSFCC for the following four reasons: (1) Six F/A-18 chase aircraft are available which could be used with the PSFCC; (2) An F/A-18 processor-in-the-loop simulation exists for validation testing; (3) The expertise has been developed in programming the research processor in the PSFCC; and (4) A well-defined process has been established for clearing flight control research projects for flight. This report presents a functional description of the PSFCC. Descriptions of the NASA DFRC facilities, PSFCC verification and validation process, and planned PSFCC projects are also provided.

26 CFR 20.6166A-2 - Definition of an interest in a closely held business.

Science.gov (United States)

2010-04-01

... Procedure and Administration § 20.6166A-2 Definition of an interest in a closely held business. (a) In... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Definition of an interest in a closely held business. 20.6166A-2 Section 20.6166A-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE...

Mutation breeding of oil seed crops. Proceedings of a final research co-ordination meeting of an FAO/IAEA co-ordinated research programme held in Vienna, 11-15 January 1993

International Nuclear Information System (INIS)

1994-12-01

The document contains 19 papers presented at the final Research Co-ordination Meeting on 'Mutation Breeding of Oil Seed Crops' held in Vienna between 11-15 January 1993. A separate abstract was prepared for each paper. Refs, figs and tabs

Regional groundwater flow in the Atikokan Research Area : simulation of 18O and 3H distributions

International Nuclear Information System (INIS)

Ophori, D.U.; Chan, Tin.

1994-09-01

AECL is investigating a concept for disposing of nuclear fuel waste deep in plutonic rock of the Canadian Shield. As part of this investigation, we have performed a model simulation of regional groundwater flow in the Atikokan Research Area, a fractured plutonic rock environment of the Canadian Shield, and used the distribution of oxygen-18 ( 18 O) and tritium ( 3 H) in groundwater to test the model. At the first stage of model calibration, groundwater flow was simulated using a three-dimensional finite-element code, MOTIF, in conjunction with a conceptual framework model derived from field geological, geophysical and hydrogeological data. Hydraulic parameters (permeability and porosity) were systematically varied until simulated recharge rates to the water table compared favourably with estimated recharge rates based on stream flow analysis. At the second stage, vertical average linear groundwater velocities from the first stage of the calibration process were combined with conceptualized one-dimensional models of the system to generate depth concentration profiles of 18 O and 3 H. Recharge-, midline-and discharge area models of both the fracture zones and the rock mass were employed. The simulated profiles formed 'envelopes' around all field 18 O and 3 H data, indicating that the calibrated velocities used in the model are reasonable. The models demonstrate that the scatter of δ 18 O and 3 H field data from the Atikokan Research Area is consistent with the groundwater flow model predictions and can be explained by the complexity arising from different hydraulic regimes (recharge, midline, discharge) and hydrogeologic environments (fracture zones, rock mass) of the regional flow system. 50 refs., 14 figs., 3 tabs

Functional and Logic Programming - 14th International Symposium (FLOPS 2018)

DEFF Research Database (Denmark)

This volume contains the proceedings of the 14th International Symposium on Functional and Logic Programming - FLOPS 2018 - held in Nagoya, Japan, May 9 - 11, 2018......This volume contains the proceedings of the 14th International Symposium on Functional and Logic Programming - FLOPS 2018 - held in Nagoya, Japan, May 9 - 11, 2018...

Germany unveils €18bn research plan

Science.gov (United States)

Banks, Michael

2009-07-01

The German government has unveiled an ambitious plan to inject a total of €18bn into teaching and research over the next decade. The German chancellor Angela Merkel, who has a degree in physics, announced that she was releasing the funds despite concerns from her social-democrat coalition partners that financing the package could be difficult in the economic downturn.

International Conference on Analytic and Algebraic Geometry held at the Tata Institute of Fundamental Research and the University of Hyderabad

CERN Document Server

Biswas, Indranil; Morye, Archana; Parameswaran, A

2017-01-01

This volume is an outcome of the International conference held in Tata Institute of Fundamental Research and the University of Hyderabad. There are fifteen articles in this volume. The main purpose of the articles is to introduce recent and advanced techniques in the area of analytic and algebraic geometry. This volume attempts to give recent developments in the area to target mainly young researchers who are new to this area. Also, some research articles have been added to give examples of how to use these techniques to prove new results.

Co-expression of the transcription factors CEH-14 and TTX-1 regulates AFD neuron-specific genes gcy-8 and gcy-18 in C. elegans.

Science.gov (United States)

Kagoshima, Hiroshi; Kohara, Yuji

2015-03-15

A wide variety of cells are generated by the expression of characteristic sets of genes, primarily those regulated by cell-specific transcription. To elucidate the mechanism regulating cell-specific gene expression in a highly specialized cell, AFD thermosensory neuron in Caenorhabditis elegans, we analyzed the promoter sequences of guanylyl cyclase genes, gcy-8 and gcy-18, exclusively expressed in AFD. In this study, we showed that AFD-specific expression of gcy-8 and gcy-18 requires the co-expression of homeodomain proteins, CEH-14/LHX3 and TTX-1/OTX1. We observed that mutation of ttx-1 or ceh-14 caused a reduction in the expression of gcy-8 and gcy-18 and that the expression was completely lost in double mutants. This synergy effect was also observed with other AFD marker genes, such as ntc-1, nlp-21and cng-3. Electrophoretic mobility shift assays revealed direct interaction of CEH-14 and TTX-1 proteins with gcy-8 and gcy-18 promoters in vitro. The binding sites of CEH-14 and TTX-1 proteins were confirmed to be essential for AFD-specific expression of gcy-8 and gcy-18 in vivo. We also demonstrated that forced expression of CEH-14 and TTX-1 in AWB chemosensory neurons induced ectopic expression of gcy-8 and gcy-18 reporters in this neuron. Finally, we showed that the regulation of gcy-8 and gcy-18 expression by ceh-14 and ttx-1 is evolutionally conserved in five Caenorhabditis species. Taken together, ceh-14 and ttx-1 expression determines the fate of AFD as terminal selector genes at the final step of cell specification. Copyright © 2015 Elsevier Inc. All rights reserved.

International conference on "Photosynthesis research for sustainability-2013: in honor of Jalal A. Aliyev", held during June 5-9, 2013, Baku, Azerbaijan.

Science.gov (United States)

Allakhverdiev, Suleyman I; Huseynova, Irada M; Govindjee

2013-12-01

In this brief report, we provide a pictorial essay on an international conference "Photosynthesis Research for Sustainability-2013 in honor of Jalal A. Aliyev" that was held in Baku, Azerbaijan, during June 5-9, 2013 ( http://photosynthesis2013.cellreg.org/ ). We begin this report with a brief note on Jalal Aliyev, the honored scientist, and on John Walker (1997 Nobel laureate in Chemistry) who was a distinguished guest and lecturer at the Conference. We briefly describe the Conference, and the program. In addition to the excellent scientific program, a special feature of the Conference was the presentation of awards to nine outstanding young investigators; they are recognized in this report. We have also included several photographs to show the pleasant ambience at this conference. (See http://photosynthesis2013.cellreg.org/Photo-Gallery.php ; https://www.dropbox.com/sh/qcr124dajwffwh6/TlcHBvFu4H?m ; and https://www.copy.com/s/UDlxb9fgFXG9/Baku for more photographs taken by the authors as well as by others.) We invite the readers to the next conferences on "Photosynthesis Research for Sustainability-2014: in honor of Vladimir A. Shuvalov" to be held during June 2-7, 2014, in Pushchino, Russia. Detailed information for this will be posted at the Website: http://photosynthesis2014.cellreg.org/ , and for the subsequent conference on "Photosynthesis Research for Sustainability-2015" to be held in May or June 2015, in Baku, Azerbaijan, at http://photosynthesis2015.cellreg.org/ .

Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5

Science.gov (United States)

Henry, Margit; Rotshteyn, Tamara; Brunn, Anna; Carstov, Mariana; Deckert, Martina; Hescheler, Jürgen; Sachinidis, Agapios; Pfitzer, Gabriele

2018-01-01

In skeletal muscle the coordinated actions of two mechanically coupled Ca2+ channels—the 1,4-dihydropyridine receptor (Cav1.1) and the type 1 ryanodine receptor (RYR1)–underlie the molecular mechanism of rapid cytosolic [Ca2+] increase leading to contraction. While both [Ca2+]i and contractile activity have been implicated in the regulation of myogenesis, less is known about potential specific roles of Cav1.1 and RYR1 in skeletal muscle development. In this study, we analyzed the histology and the transcriptomic changes occurring at E14.5 –the end of primary myogenesis and around the onset of intrauterine limb movement, and at E18.5 –the end of secondary myogenesis, in WT, RYR1-/-, and Cav1.1-/- murine limb skeletal muscle. At E14.5 the muscle histology of both mutants exhibited initial alterations, which became much more severe at E18.5. Immunohistological analysis also revealed higher levels of activated caspase-3 in the Cav1.1-/- muscles at E14.5, indicating an increase in apoptosis. With WT littermates as controls, microarray analyses identified 61 and 97 differentially regulated genes (DEGs) at E14.5, and 493 and 1047 DEGs at E18.5, in RYR1-/- and Cav1.1-/- samples, respectively. Gene enrichment analysis detected no overlap in the affected biological processes and pathways in the two mutants at E14.5, whereas at E18.5 there was a significant overlap of DEGs in both mutants, affecting predominantly processes linked to muscle contraction. Moreover, the E18.5 vs. E14.5 comparison revealed multiple genotype-specific DEGs involved in contraction, cell cycle and miRNA-mediated signaling in WT, neuronal and bone development in RYR1-/-, and lipid metabolism in Cav1.1-/- samples. Taken together, our study reveals discrete changes in the global transcriptome occurring in limb skeletal muscle from E14.5 to E18.5 in WT, RYR1-/- and Cav1.1-/- mice. Our results suggest distinct functional roles for RYR1 and Cav1.1 in skeletal primary and secondary myogenesis. PMID

Report of the Interagency Optical Network Testbeds Workshop 2, NASA Ames Research Center, September 12-14, 2005

Science.gov (United States)

2005-01-01

The Optical Network Testbeds Workshop 2 (ONT2), held on September 12-14, 2005, was cosponsored by the Department of Energy Office of Science (DOE/SC) and the National Aeronautics and Space Administration (NASA), in cooperation with the Joint Engineering Team (JET) of the Federal Networking and Information Technology Research and Development (NITRD) Program's Large Scale Networking (LSN) Coordinating Group. The ONT2 workshop was a follow-on to an August 2004 Workshop on Optical Network Testbeds (ONT1). ONT1 recommended actions by the Federal agencies to assure timely development and implementation of optical networking technologies and infrastructure. Hosted by the NASA Ames Research Center in Mountain View, California, the ONT2 workshop brought together representatives of the U.S. advanced research and education (R&E) networks, regional optical networks (RONs), service providers, international networking organizations, and senior engineering and R&D managers from Federal agencies and national research laboratories. Its purpose was to develop a common vision of the optical network technologies, services, infrastructure, and organizations needed to enable widespread use of optical networks; recommend activities for transitioning the optical networking research community and its current infrastructure to leading-edge optical networks over the next three to five years; and present information enabling commercial network infrastructure providers to plan for and use leading-edge optical network services in that time frame.

Private is Public?! Der Umgang von 14- bis 18-Jährigen mit Sozialen Medien. - Eine explorativ-empirische Untersuchung im gymnasialen Kontext

Directory of Open Access Journals (Sweden)

Christian Filk

2011-12-01

Full Text Available Die explorative Studie „Private is Public?!“ fokussiert sich auf das Mediennutzungsverhalten von 14- bis 18-jährigen Schülerinnen und Schülern mit Schwerpunkt soziale Medien. Das Forscherteam führte seine empirische Untersuchung am Mons-Tabor-Gymnasium im ländlich gelegenen Montabaur, Rheinland-Pfalz (Deutschland durch. Gestützt auf Forschungshypothesen erhoben Christian Filk, Hanno Schauer und Amina Ovcina Cajacob mit Hilfe des Instruments der schriftlichen Befragung aktuelle Trends zu Frequenz und Intensität der Nutzung sozialer Medien, zur zweckbezogenen Nutzung sozialer Medien, zu Informationsverhaltensschemata in sozialen Medien sowie zu Erfahrungen mit Cyber-Mobbing. Die gewonnenen Daten werden mittels deskriptiv-statistischer Analysen ausgewertet. Schliesslich diskutieren Verfasser und Verfasserin den innovativen Einsatz privater sozialer Medien für den Unterricht in öffentlichen Schulen. The explorative study “Private is Public?!” focuses on the use of media of 14- to 18-years-old students with a special focus on social media. The research team conducted its empirical investigation at Mons Tabor High School in the rural area of Montabaur, Rhineland-Palatinate (Germany. Based on research hypothesis Christian Filk, Hanno Schauer and Amina Ovcina Cajacob are using written surveys in order to identify current trends in frequency and intensity of performing social media, purpose-oriented use of social media, information-seeking behavior patterns in social media, and last but not least experiences with cyber-bullying. The collected data are evaluated by using descriptive statistical analysis. Finally, the authors discuss the innovative use of private social media for teaching in public schools.

Report of the Review Committee on valuation of the research subjects in the fields of advanced science research

International Nuclear Information System (INIS)

2000-07-01

On the basis of the JAERI's Basic Guidelines for the Research Evaluation Methods, etc. the Ad Hoc Review Committee composed of eight experts was set up under the Research Evaluation Committee of the JAERI in order to review the research theme completed in FY1998 and those planned for five years starting in FY2000 in the Advanced Science Research Center. The Ad Hoc Review Committee meeting was held on September 17, 1999. According to the review methods including review items, points of review and review criteria, determined by the Research Evaluation Committee, the review was conducted based on the research results/plan documents submitted in advance and presentations by the Research Group Leaders. The review report was submitted to the Research Evaluation Committee for further review and discussions in its meeting held on March 14, 2000. As a result, the Research Evaluation Committee acknowledged appropriateness of the review results. This report describes the review results. (author)

Proceedings of the first symposium on advanced photon research

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-03-01

This report consists of 76 contributed papers of the First Symposium on Advanced Photon Research, which was held at Keihanna Plaza and JAERI Advanced Photon Research Center in Kyoto on November 8-9, 1999. The numbers of oral presentations including a special invited talk and poster presentations were 14 and 68, respectively. (J.P.N.)

Fluorine-18 radiopharmaceuticals beyond [18F]FDG for use in oncology and neurosciences

International Nuclear Information System (INIS)

Coenen, H.H.; Elsinga, P.H.; Iwata, R.; Kilbourn, M.R.; Pillai, M.R.A.; Rajan, M.G.R.; Wagner, H.N.; Zaknun, J.J.

2010-01-01

Positron emission tomography (PET) is a rapidly expanding clinical modality worldwide thanks to the availability of compact medical cyclotrons and automated chemistry for the production of radiopharmaceuticals. There is an armamentarium of fluorine-18 ( 18 F) tracers that can be used for PET studies in the fields of oncology and neurosciences. However, most of the 18 F-tracers other than 2-deoxy-2-[18F]fluoro-D-glucose (FDG) are in less than optimum human use and there is considerable scope to bring potentially useful 18 F-tracers to clinical investigation stage. The International Atomic Energy Agency (IAEA) convened a consultants' group meeting to review the current status of 18 F-based radiotracers and to suggest means for accelerating their use for diagnostic applications. The consultants reviewed the developments including the synthetic approaches for the preparation of 18 F-tracers for oncology and neurosciences. A selection of three groups of 18 F-tracers that are useful either in oncology or in neurosciences was done based on well-defined criteria such as application, lack of toxicity, availability of precursors and ease of synthesis. Based on the recommendations of the consultants' group meeting, IAEA started a coordinated research project on 'Development of 18 F radiopharmaceuticals (beyond [ 18 F]FDG) for use in oncology and neurosciences' in which 14 countries are participating in a 3-year collaborative program. The outcomes of the coordinated research project are expected to catalyze the wider application of several more 18 F-radiopharmaceuticals beyond FDG for diagnostic applications in oncology and neurosciences.

Center of Excellence for Geospatial Information Science research plan 2013-18

Science.gov (United States)

Usery, E. Lynn

2013-01-01

The U.S. Geological Survey Center of Excellence for Geospatial Information Science (CEGIS) was created in 2006 and since that time has provided research primarily in support of The National Map. The presentations and publications of the CEGIS researchers document the research accomplishments that include advances in electronic topographic map design, generalization, data integration, map projections, sea level rise modeling, geospatial semantics, ontology, user-centered design, volunteer geographic information, and parallel and grid computing for geospatial data from The National Map. A research plan spanning 2013–18 has been developed extending the accomplishments of the CEGIS researchers and documenting new research areas that are anticipated to support The National Map of the future. In addition to extending the 2006–12 research areas, the CEGIS research plan for 2013–18 includes new research areas in data models, geospatial semantics, high-performance computing, volunteered geographic information, crowdsourcing, social media, data integration, and multiscale representations to support the Three-Dimensional Elevation Program (3DEP) and The National Map of the future of the U.S. Geological Survey.

Proceedings of the fourth symposium on advanced photon research

International Nuclear Information System (INIS)

2003-07-01

This report consists of 67 contributed papers of the Fourth Symposium on Advanced Photon Research, which was held at JAERI Advanced Photon Research Center in Kyoto on November 28-29, 2002. The numbers of speeches were 14, including 5 invited speeches, and the numbers of poster presentations were 62, including FY 2001 joint research and cooperative research presentations. The 66 of the presented papers are indexed individually. (J.P.N.)

Ultrasonography with a hand-held device for the diagnosis of acute appendicitis

International Nuclear Information System (INIS)

Kameda, Toru; Takahashi, Isao

2009-01-01

The purpose of this study was to evaluate the accuracy of ultrasonography (US) with a hand-held device for the diagnosis of acute appendicitis in the emergency room. US with a hand-held device was performed by the first author in 33 patients suspected of having appendicitis in the emergency room. From these 33 patients, 24 who subsequently underwent computed tomography (CT) or surgery were included in this study. The accuracy of US with the hand-held device for the diagnosis of acute appendicitis was evaluated based on the findings of CT or surgery. CT and surgery were performed in 22 and 12 patients, respectively. Final diagnoses were acute appendicitis (n=18), terminal ileitis (n=2), pelvic inflammatory disease (n=2), diverticulitis (n=1), and ureterolithiasis (n=1). The US yielded a sensitivity of 78% and a positive predictive value of 100%. The shortest distance between the abdominal wall and the appendix measured on CT was less than 40 mm in 11 patients. In ten (91%) of the 11 patients US with the hand-held device showed the swollen appendix. US with a hand-held device is potentially useful in the positive identification of acute appendicitis, but further investigation is needed to prove its utility in the routine diagnosis of acute appendicitis. (author)

Abraham Reef Stable Isotope Data (delta 13C, delta 18O, delta 14C) for 1635-1957

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Site: Abraham Reef, 22ó 06'S, 153ó 00'E, Porites australiensus, Radiocarbon (delta 14C) and Stable Isotope (del 18O and del 13C) results from bi-annual samples from...

DOE-NSF-NIH Workshop on Opportunities in THz Science, February 12-14, 2004

Energy Technology Data Exchange (ETDEWEB)

Sherwin, M.A.; Bucksbaum, P.H.; Schmuttenmaer, C. A.; Allen, J.; Biedron, S.; Carr, L.; Chamberlain, M.; Crowe, T.; DeLucia, F.; Hu, Q.; Jones, B.; Noordham, B.; Norris, T.; Orenstein, J.; Unterrainer, K.; Van der Meer, L.; Wilke, I.; Williams, G.; Zhang, X.-C.; Cheville, A.; Markelz, A.; Parks, B.; Plancken, P.; Shan, J.; Austin, B.; Basov, D.; Citrin, D.; Grundfest, W.; Heinz, T.; Kono, J.; Mittleman, D.; Siegel, P.; Taylor, T.; Jones, B.; Markelz, A.; Martin, M.; Nelson, K.; Smith, T.; Williams, G.; Allen, M.; Averitt, R.; Brunel, L.; Heilweil, T.; Heyman, J.; Jepsen, P.; Kaind, R.; Leemans, W.; Mihaly, L.; Rangan, C.; Tom, H.; Wallace, V.; Zimdars, D.

2004-02-14

This is the report of the Workshop on Opportunities in THz Science, held on February 12-14, 2004 in Arlington, VA. This workshop brought together researchers who use or produce THz radiation for physics, chemistry, biology, medicine, and materials science to discuss new research opportunities and common resource needs. The charge from the sponsors of the workshop was to focus on basic science questions within these disciplines that have and can be answered using THz radiation.

Waste management research abstracts no. 14

International Nuclear Information System (INIS)

1983-04-01

The present 14th issue is the second of the new series of Waste Management Research Abstracts, which are reappearing after a three-year suspension. The new series appears in a substantially innovated form. Although the objective of the publication is the same as before, namely to collect and disseminate information on research in progress in the field of nuclear waste management, the format for presentation of the information is a new data sheet in a standardized form, access to which will be made possible by different indexes. The 408 research data sheets contained in this issue have been collected during recent months, ending 15 January 1983, and reflect research currently in progress. They were sent by the Governments of twenty-five Member States, by the International Atomic Energy Agency, and by the Commission of the European Communities. Though the information contained in this publication covers a wide range of subjects in various countries, the WMRA should not be interpreted as providing a complete survey of on-going research in IAEA Member States

Elastic electron scattering from 14N, 15N, 16O and 18O at small momentum transfer

International Nuclear Information System (INIS)

Schuetz, W.

1973-01-01

At the Darmstadt linear accelerator, cross-sections for the elastic scattering of electrons on 14 N and 16 O relative to the proton and on 15 N and 18 O relative to 14 N and 16 O were measured at energies 30 MeV 0 0 (q 2 -2 ). The experiments were done with gas targets, the target containers being thin-walled aluminium cylinders. The data were evaluated by means of the partial-wave method assuming a charge distribution according to the shell model. (orig./WL) [de

Evaluation of austenitic stainless steels for transpassive corrosion by metal purification technology. Synergistic effect of Si and P on intergranular corrosion of Fe-18Cr-14Ni alloys

International Nuclear Information System (INIS)

Mayuzumi, Masami; Ohta, Joji; Kako, Kenji; Kawakami, Eishi

2001-01-01

The synergistic effect of Si, Mn, C, P, and S on the transpassive corrosion of HP18Cr-14Ni alloys was studied in 13N nitric acid. The specimens were fabricated using a cold crucible method in a high-vacuum chamber to reduce contamination. The additions of Si<1% and Mn<2% had no effect on the corrosion behavior of HP18Cr-14Ni alloys, and the addition of Si<1% also had no effect on the corrosion behavior of HP18Cr-14Ni-1Mn alloys, although 1% Si induced intergranular corrosion in both the alloys. Thus, HP18Cr-14Ni-1Mn-0.5Si alloys were selected to evaluate the effects of C, P and S (100 ppm each). The addition of P, and the co-addition of C, P, and S to HP18Cr-14Ni-1Mn-0.5Si induced intergranular corrosion of the same degree in the solution annealed condition. This result suggests the synergistic effect of Si and P to induce intergranular corrosion, since the single addition of Si or P to this level did not lead to intergranular corrosion of HP18Cr-14Ni alloys. HP18Cr-14Ni-1Mn-0.5Si alloys containing C, P, and S at the 100 ppm level each showed superior corrosion resistance compared to a commercial Type 304L in 13N nitric acid. (author)

Are percutaneous transgastric biopsies using 14-,16- and 18-G Tru-Cut needles safe? An experimental study in the rabbit

International Nuclear Information System (INIS)

Akan, H.; Incesu, L.; Gunes, M.; Ozen, N.; Gumus, S.

1998-01-01

We evaluated perforation, peritonitis and bleeding after 14-, 16-, 18-G Tru-Cut needles were passed through the stomach in an animal model. Insertions were performed on seven anesthetized rabbits with 18-,16-and 14-G needles simulating the clinical technique. Diluted contrast medium with methylene blue (60mL) was administered through a nasogastric tube after the biopsy. Computed tomography (CT) scanning of the upper abdomen was performed 10 minutes after the insertion for leakage. The abdominal contents were inspected by laparotomy. There was no contrast medium leakage outside the gastrointestinal tract on CT images. Neither methylene blue nor other stomach content leakage was identified by laparotomy, even with manual squeezing. A tiny spot of blood was observed on the serosal surface of the stomach with the 18-G needle passes (five cases), whereas a relatively large haematoma was present with 14-G needle (four cases). Six of the rabbits survived and one died due to an inadvertant aortic injury. The results of the study show that transgastric route with an 1 8-G cutting needle can be used without fear of peritonitis and bleeding. Copyright (1998) Blackwell Science Pty Ltd

Are percutaneous transgastric biopsies using 14-,16- and 18-G Tru-Cut needles safe? An experimental study in the rabbit

Energy Technology Data Exchange (ETDEWEB)

Akan, H.; Incesu, L.; Gunes, M. [Ondokuz Mayis University Medical School, Samsun (Turkey). Department of Radiology; Ozen, N.; Gumus, S. [Ondokuz Mayis University Medical School, Samsun (Turkey). Department of Surgery

1998-05-01

We evaluated perforation, peritonitis and bleeding after 14-, 16-, 18-G Tru-Cut needles were passed through the stomach in an animal model. Insertions were performed on seven anesthetized rabbits with 18-,16-and 14-G needles simulating the clinical technique. Diluted contrast medium with methylene blue (60mL) was administered through a nasogastric tube after the biopsy. Computed tomography (CT) scanning of the upper abdomen was performed 10 minutes after the insertion for leakage. The abdominal contents were inspected by laparotomy. There was no contrast medium leakage outside the gastrointestinal tract on CT images. Neither methylene blue nor other stomach content leakage was identified by laparotomy, even with manual squeezing. A tiny spot of blood was observed on the serosal surface of the stomach with the 18-G needle passes (five cases), whereas a relatively large haematoma was present with 14-G needle (four cases). Six of the rabbits survived and one died due to an inadvertant aortic injury. The results of the study show that transgastric route with an 1 8-G cutting needle can be used without fear of peritonitis and bleeding. Copyright (1998) Blackwell Science Pty Ltd 19 refs., 1 tab., 1 fig.

Health physics research abstracts No.14: Information on research in progress

International Nuclear Information System (INIS)

1989-01-01

The present issue No. 14 of Health Physics Research Abstracts is the continuation of a series of bulletins published by the Agency since 1967. They collect reports from Member States on Health Physics research in progress or just completed. The main aim in issuing such reports is to draw attention to work that is about to be published and to enable interested scientists to obtain further information through direct correspondence with the investigator. The present issue contains 381 reports received up to September 1988

JANNAF 18th Propulsion Systems Hazards Subcommittee Meeting. Volume 1

Science.gov (United States)

Cocchiaro, James E. (Editor); Gannaway, Mary T. (Editor)

1999-01-01

This volume, the first of two volumes is a compilation of 18 unclassified/unlimited-distribution technical papers presented at the Joint Army-Navy-NASA-Air Force (JANNAF) 18th Propulsion Systems Hazards Subcommittee (PSHS) meeting held jointly with the 36th Combustion Subcommittee (CS) and 24th Airbreathing Propulsion Subcommittee (APS) meetings. The meeting was held 18-21 October 1999 at NASA Kennedy Space Center and The DoubleTree Oceanfront Hotel, Cocoa Beach, Florida. Topics covered at the PSHS meeting include: shaped charge jet and kinetic energy penetrator impact vulnerability of gun propellants; thermal decomposition and cookoff behavior of energetic materials; violent reaction; detonation phenomena of solid energetic materials subjected to shock and impact stimuli; and hazard classification, insensitive munitions, and propulsion systems safety.

Driver hand-held cellular phone use: a four-year analysis.

Science.gov (United States)

Eby, David W; Vivoda, Jonathon M; St Louis, Renée M

2006-01-01

The use of hand-held cellular (mobile) phones while driving has stirred more debate, passion, and research than perhaps any other traffic safety issue in the past several years. There is ample research showing that the use of either hand-held or hands-free cellular phones can lead to unsafe driving patterns. Whether or not these performance deficits increase the risk of crash is difficult to establish, but recent studies are beginning to suggest that cellular phone use elevates crash risk. The purpose of this study was to assess changes in the rate of hand-held cellular phone use by motor-vehicle drivers on a statewide level in Michigan. This study presents the results of 13 statewide surveys of cellular phone use over a 4-year period. Hand-held cellular phone use data were collected through direct observation while vehicles were stopped at intersections and freeway exit ramps. Data were weighted to be representative of all drivers traveling during daylight hours in Michigan. The study found that driver hand-held cellular phone use has more than doubled between 2001 and 2005, from 2.7% to 5.8%. This change represents an average increase of 0.78 percentage points per year. The 5.8% use rate observed in 2005 means that at any given daylight hour, around 36,550 drivers were conversing on cellular phones while driving on Michigan roadways. The trend line fitted to these data predicts that by the year 2010, driver hand-held cellular phone use will be around 8.6%, or 55,000 drivers at any given daylight hour. These results make it clear that cellular phone use while driving will continue to be an important traffic safety issue, and highlight the importance of continued attempts to generate new ways of alleviating this potential hazard.

Sub-scale Direct Connect Supersonic Combustion Facility (Research Cell 18)

Data.gov (United States)

Federal Laboratory Consortium — Description: RC18 is a continuous-flow, direct-connect, supersonic-combustion research facility that is capable of simulating flight conditions from Mach 3.0 to Mach...

Proceedings of the fifth symposium on advanced photon research

International Nuclear Information System (INIS)

2004-06-01

This report consists of 69 contributed papers of the Fifth Symposium on Advanced Photon Research, which was held at JAERI-Kansai in Kyoto on November 20-21, 2003. The numbers of speeches were 14, including 4 invited speeches, and the numbers of poster presentations were 60, including FY2002 and cooperative research and joint research presentations. The 69 of the presented papers are indexed individually. (J.P.N.)

Patellar tendinopathy in junior basketball players: a controlled clinical and ultrasonographic study of 268 patellar tendons in players aged 14-18 years.

Science.gov (United States)

Cook, J L; Khan, K M; Kiss, Z S; Griffiths, L

2000-08-01

Anterior knee pain is a common presenting complaint amongst adolescent athletes. We hypothesised that patellar tendinopathy may occur at a younger age than is generally recognised. Thus, we studied the patellar tendons in 134 elite 14- to 18-year-old female (n=64) and male (n=70) basketball players and 29 control swimmers (17 female, 12 male) clinically and with ultrasonography. We found that of 268 tendons, 19 (7%) had current patellar tendinopathy on clinical grounds (11% in males, 2% in females). Twenty-six percent of the basketball players' patellar tendons contained an ultrasonographic hypoechoic region. Ultrasonographic abnormality was more prevalent in the oldest tertile of players (17-18 years) than the youngest tertile (14-15.9 years). Of tendons categorised clinically as 'Never patellar tendinopathy', 22% had an ultrasonographic hypoechoic region nevertheless. This study indicates that patellar tendinopathy can occur in 14- to 18-year-old basketball players. Ultrasonographic tendon abnormality is 3 times as common as clinical symptoms.

18th International Conference on Electronic Publishing

CERN Document Server

Dobreva, Milena

2014-01-01

The ways in which research data is used and handled continue to capture public attention and are the focus of increasing interest. Electronic publishing is intrinsic to digital data management, and relevant to the fields of data mining, digital publishing and social networks, with their implications for scholarly communication, information services, e-learning, e-business and the cultural heritage sector. This book presents the proceedings of the 18th International Conference on Electronic Publishing (ELPUB), held in Thessaloniki, Greece, in June 2014. The conference brings together researchers and practitioners to discuss the many aspects of electronic publishing, and the theme this year is 'Let's put data to use: digital scholarship for the next generation'. As well as examining the role of cultural heritage and service organisations in the creation, accessibility, duration and long-term preservation of data, it provides a discussion forum for the appraisal, citation and licensing of research data and the n...

75 FR 72872 - Rehabilitation Research and Development Service Scientific Merit Review Board; Notice of Meeting

Science.gov (United States)

2010-11-26

... DEPARTMENT OF VETERANS AFFAIRS Rehabilitation Research and Development Service Scientific Merit...-463 (Federal Advisory Committee Act) that a meeting of the Rehabilitation Research and Development Service Scientific Merit Review Board will be held on December 13-14, 2010, at the Hilton Alexandria Old...

Comparison of [{sup 18}F]FHBG and [{sup 14}C]FIAU for imaging of HSV1-tk reporter gene expression: adenoviral infection vs stable transfection

Energy Technology Data Exchange (ETDEWEB)

Min, Jung-Jun; Iyer, Meera [The Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology, UCLA School of Medicine, B3-399A BRI 700 Westwood Plaza, CA 90095-1770, Los Angeles (United States); Gambhir, Sanjiv S. [The Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology, UCLA School of Medicine, B3-399A BRI 700 Westwood Plaza, CA 90095-1770, Los Angeles (United States); Department of Radiology, Bio-X Program, Stanford University, Stanford, California (United States)

2003-11-01

Earlier studies involving comparison of different reporter probes have shown conflicting results between pyrimidine nucleosides [e.g., 2'-fluoro-2'-deoxy-1-{beta}-d-arabinofuranosyl-5-iodouracil (FIAU)] and acycloguanosine derivatives [e.g., penciclovir (PCV), 9-(4-fluoro-3-hydroxymethylbutyl)guanine (FHBG)]. We hypothesized that this reported discrepancy may be related to how the reporter gene is delivered to the cells - stably transfected vs adenoviral infection. We directly compared the uptake characteristics of [{sup 18}F]FHBG, [{sup 3}H]PCV, and [{sup 14}C]FIAU in cell culture and in vivo using an adenoviral mediated gene transfer model and stably transfected cells. We further compared the uptake of three reporter probes using both HSV1-tk and a mutant HSV1-sr39tk expressing cells to assess the optimal reporter probe/reporter gene combination. [{sup 14}C]FIAU accumulation was greater than that of [{sup 3}H]PCV and [{sup 18}F]FHBG in control cells and in HSV1-tk stably transfected cells (P<0.001). After infection of C6 cells with AdCMV-HSV1-tk (1.5 x 10{sup 8} pfu), [{sup 18}F]FHBG and [{sup 3}H]PCV accumulation was significantly greater than that of [{sup 14}C]FIAU (P<0.01). [{sup 18}F]FHBG and [{sup 3}H]PCV accumulated to a significantly greater extent than [{sup 14}C]FIAU in C6-stb-sr39tk+ and AdCMV-HSV1-sr39tk infected C6 cells (P<0.001). Results from the nude mice supported the results in cell culture. [{sup 14}C]FIAU led to significantly higher %ID/g in C6-stb-tk+ xenografts than [{sup 18}F]FHBG (P<0.05); however, compared with [{sup 14}C]FIAU, [{sup 18}F]FHBG led to as high %ID/g in HSV1-tk expressing hepatocytes and to significantly greater %ID/g in C6-stb-sr39tk+ xenografts and HSV1-sr39tk expressing hepatocytes. Dynamic sequential images showed that [{sup 18}F]FHBG was well retained in HSV1-sr39tk expressing cells (C6-stb-sr39tk+) for at least 4 h after injection, while it was rapidly cleared from HSV1-tk expressing cells (MH3924A

Effect of Needle Size in Ultrasound-guided Core Needle Breast Biopsy: Comparison of 14-, 16-, and 18-Gauge Needles.

Science.gov (United States)

Giuliani, Michela; Rinaldi, Pierluigi; Rella, Rossella; Fabrizi, Gina; Petta, Federica; Carlino, Giorgio; Di Leone, Alba; Mulè, Antonino; Bufi, Enida; Romani, Maurizio; Belli, Paolo; Bonomo, Lorenzo

2017-11-01

The aim of the present study was to assess the diagnostic accuracy of ultrasound-guided core needle biopsy (US-CNB) of breast lesions, comparing smaller needles (16- and 18-gauge) with the 14-gauge needle, and to analyze the lesion characteristics influencing US-CNB diagnostic performance. All the patients provided informed consent before the biopsy procedure. The data from breast lesions that had undergone US-CNB in our institution from January 2011 to January 2015 were retrospectively reviewed. The inclusion criterion was the surgical histopathologic examination findings of the entire lesion or radiologic follow-up data for ≥ 24 months. The exclusion criterion was the use of preoperative neoadjuvant therapy. The US-CNB results were compared with the surgical pathologic results or with the follow-up findings in the 3 needle size groups (14-, 16-, and 18-gauge). The needle size- and lesion characteristic-specific diagnostic accuracy parameters were evaluated. Statistical analysis was performed using a dedicated software program, and P ≤ .01 was considered significant. A total of 1118 US-CNB cases (1042 patients) were included. Of the 1118 cases, 630 (56.3%) were in the 14-gauge group, 136 (12.2%) in the 16-gauge, and 352 (31.5%) in the 18-gauge needle group. Surgery was performed on 800 lesions (71.6%). Of these, 619 were malignant, 77 were high risk, and 104 were benign. The remaining 318 lesions (28.4%) underwent follow-up imaging studies. All the lesions were stable and, therefore, were considered benign. No differences were observed in the diagnostic accuracy parameters among the 3 needle size groups (P > .01). The false-negative rate was greater for lesions  .01). US-CNB performed with small needles (16 and 18 gauge) had the same diagnostic accuracy as that performed with 14-gauge needles, regardless of the lesion characteristics. Copyright © 2017 Elsevier Inc. All rights reserved.

14th International Probabilistic Workshop

CERN Document Server

Taerwe, Luc; Proske, Dirk

2017-01-01

This book presents the proceedings of the 14th International Probabilistic Workshop that was held in Ghent, Belgium in December 2016. Probabilistic methods are currently of crucial importance for research and developments in the field of engineering, which face challenges presented by new materials and technologies and rapidly changing societal needs and values. Contemporary needs related to, for example, performance-based design, service-life design, life-cycle analysis, product optimization, assessment of existing structures and structural robustness give rise to new developments as well as accurate and practically applicable probabilistic and statistical engineering methods to support these developments. These proceedings are a valuable resource for anyone interested in contemporary developments in the field of probabilistic engineering applications.

Níveis de maturidade vocacional de alunos de 14 a 18 anos do Rio Grande do Sul Niveles de madurez vocacional de alumnos de 14 a 18 años de Rio Grande do Sul Levels of vocational maturity in high school students, aged 14 to 18, in Rio Grande do Sul

Directory of Open Access Journals (Sweden)

Marcos Alencar Abaide Balbinotti

2006-12-01

Full Text Available Maturidade vocacional é a capacidade de enfrentar tarefas de desenvolvimento com as quais se é confrontado; como conseqüência do próprio desenvolvimento social e biológico e das necessidades da sociedade em relação às pessoas que alcançam esse estado de desenvolvimento. O estudo explora diferenças nos níveis de maturidade vocacional segundo sexo, idade, ano do ensino médio e tipo de escola. Uma amostra de 860 estudantes do ensino médio, de ambos os sexos e idades de 14 a 18 anos, das redes pública e privada, respondeu o Questionário de Educação à Carreira (QEC. Resultados indicam diferenças significativas (pMadurez vocacional es la capacidad de enfrentarse tareas de desarrollo con las cuales se es confrontado; como consecuencia del propio desarrollo social y biológico y de las necesidades de la sociedad en relación con las personas que alcanzan ese estado de desarrollo. El estudio explora diferencias en los niveles de madurez vocacional según el sexo, edad, año de Enseñanza Media y tipo de escuela. Una muestra de 860 estudiantes de Enseñanza Media, de ambos sexos y edades de 14 a 18 años, de las redes pública y privada, respondió el Cuestionario de Educación a la Carrera (QEC. Resultados indican diferencias significativas (pVocational maturity is the capacity to face the development tasks, which one is confronted with as a consequence of one' s own social-biological development and society' s expectations for the individuals who reach such a condition of development. Differences regarding the levels of vocational maturity are explored in this study, according to sex, age, level of high school education and type of school attended. A sample of 860 high school students - from14 to 18 years old, male and female, attending public and private schools - answered the Questionnaire related to Career Education (QCE. The results show significant differences (p<0.05 when variables such as sex, type of school and level of high

Proceeding of the third symposium of large data management for creative research

International Nuclear Information System (INIS)

Ueshima, Yutaka

2002-06-01

This report consists of 11 contributed papers of the Third Symposium of Large Data Management for Creative Research, which was held at the JAERI Advanced Photon Research Center in Kyoto on October 29-31. The number of oral presentations was 14. This proceeding includes copies of slides from the first and second symposium. (author)

Automation Study for Longhorn Army Ammunition Plant Hand Held Signal Flight Assembly, Rocket Barrel Assembly, 40 MM Signal, Final Packaging/Pack-Out, and Star Finishing

Science.gov (United States)

1990-03-01

wood protectors in the HHS Rocket Barrel Assembly Operations. d) Use of hot melt sealant rather than lacquer on the end of the assembled Hand Held...4OL.UA8LYADHRlE CG411!cLVPAM-1 ~LW7m~I~o~c~c LCA ~TM18UX"Y.31nSRGU-11 STiIM ASSELYJMACE FINh1TZ1A1*4CWAJKRZAM’ WAOiNt rs~my" LOCATM1ED 0~7 LOCA1ED’ IWCM-1W...Moorfeed Fairview, PA Indianapolis, IN Voice Synthesis Module Square D Micro Chip Technology Palatine, IL Chandler, AZ 85224 Vacuum Unit Venturi’s

Research on digestive and liver diseases: a priority for Europe - the societal importance of gastrointestinal diseases and research.

Science.gov (United States)

Stockbrugger, Reinhold; Quaglio, GianLuca; O'Morain, Colm; Rubig, Paul; Manns, Michael

2013-08-01

On 18 September 2012, in the European Parliament in Brussels, a public meeting was held between Science and Technology Options Assessments of the Parliament and the United European Gastroenterology to review the position of gastrointestinal and liver research in the context of the European Union. The meeting reflected the past situation, the ongoing close collaboration as well as facts and options on the upcoming European Union research programme Horizon 2020 that is in planning and will cover the years from 2014 to 2020.

18th International Cryocooler Conference

CERN Document Server

Ross, Ronald G

2014-01-01

Cryocoolers 18 Cryocoolers 18 archives developments and performance measurements in the field of cryocoolers based on the contributions of leading international experts at the 18th International Cryocooler Conference that was held in Syracuse, New York, on June 9-12, 2014. The program of this conference lead to the 76 peer-reviewed papers that are published here. Over the years the International Cryocoolers Conference has become the preeminent worldwide conference for the presentation of the latest developments and test experiences with cryocoolers. The typical applications of this technology include cooling space and terrestrial infrared focal plane arrays, space x-ray detectors, medical applications, and a growing number of high-temperature superconductor applications.

18th Middle Atlantic Regional Meeting, American Chemical Society

International Nuclear Information System (INIS)

Anon.

1985-01-01

The Proceedings of the 18th Middle Atlantic Regional Meeting of the American Chemical Society held May 21-23, 1984, include information about the meeting, e.g. area map and list of exhibitors, and abstracts for most of the 397 papers. A few papers are only title listed. The papers are arranged into sections dealing with analytical chemistry, biochemistry, chemical education, environmental chemistry, fuel chemistry, history of chemistry, industrial and engineering chemistry, inorganic chemistry, photochemistry, physical chemistry, polymer chemistry, and polymeric materials. Sections are also included to highlight undergraduate research and papers by chemical technicians and younger chemists. Separate abstracts have been prepared for 36 papers

Generation of Novel Traj18-Deficient Mice Lacking Vα14 Natural Killer T Cells with an Undisturbed T Cell Receptor α-Chain Repertoire.

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Nyambayar Dashtsoodol

Full Text Available Invariant Vα14 natural killer T (NKT cells, characterized by the expression of a single invariant T cell receptor (TCR α chain encoded by rearranged Trav11 (Vα14-Traj18 (Jα18 gene segments in mice, and TRAV10 (Vα24-TRAJ18 (Jα18 in humans, mediate adjuvant effects to activate various effector cell types in both innate and adaptive immune systems that facilitates the potent antitumor effects. It was recently reported that the Jα18-deficient mouse described by our group in 1997 harbors perturbed TCRα repertoire, which raised concerns regarding the validity of some of the experimental conclusions that have been made using this mouse line. To resolve this concern, we generated a novel Traj18-deficient mouse line by specifically targeting the Traj18 gene segment using Cre-Lox approach. Here we showed the newly generated Traj18-deficient mouse has, apart from the absence of Traj18, an undisturbed TCRα chain repertoire by using next generation sequencing and by detecting normal generation of Vα19Jα33 expressing mucosal associated invariant T cells, whose development was abrogated in the originally described Jα18-KO mice. We also demonstrated here the definitive requirement for NKT cells in the protection against tumors and their potent adjuvant effects on antigen-specific CD8 T cells.

18 CFR 367.14 - Transactions with associate companies.

Science.gov (United States)

2010-04-01

... all transactions with associate companies. The statements may be required to show the general nature... associate companies. 367.14 Section 367.14 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY HOLDING COMPANY ACT OF 2005...

A History of the Acoustics Division of the Naval Research Laboratory: The First Eight Decades 1923 - 2008

Science.gov (United States)

2013-08-01

Wilson 9-Gerald Morris 10-Wayne Kinney 11-Pat Carter 12-Ed Besancon 13-Karen Dudley 14-Mary Rowe 15-Tony Pogue 16-Stephanie Kooney 17-Lisa Pflug 18...Leybourne R.W. Meredith C.T. Mire G.B. Morris V.M. Ross K.D. Savage A.S. Smith 7173 Shallow Water & Coastal Acoustics H.B. Ali M.K...Interview with Dr. Budd B. Adams held on Tuesday 23 April 2008 at 1130 AM EDT (1 hour 30 minutes) [Dr. Adams’ revisions received 14 October 2008

Analytical characterization of ch14.18: a mouse-human chimeric disialoganglioside-specific therapeutic antibody.

Science.gov (United States)

Soman, Gopalan; Kallarakal, Abraham T; Michiel, Dennis; Yang, Xiaoyi; Saptharish, Nirmala; Jiang, Hengguang; Giardina, Steve; Gilly, John; Mitra, George

2012-01-01

Ch14.18 is a mouse-human chimeric monoclonal antibody to the disialoganglioside (GD2) glycolipid. In the clinic, this antibody has been shown to be effective in the treatment of children with high-risk neuroblastoma, either alone or in combination therapy. Extensive product characterization is a prerequisite to addressing the potential issues of product variability associated with process changes and manufacturing scale-up. Charge heterogeneity, glycosylation profile, molecular state and aggregation, interaction (affinity) with Fcγ receptors and functional or biological activities are a few of the critical characterization assays for assessing product comparability for this antibody. In this article, we describe the in-house development and qualification of imaged capillary isoelectric focusing to assess charge heterogeneity, analytical size exclusion chromatography with online static and dynamic light scattering (DLS), batch mode DLS for aggregate detection, biosensor (surface plasmon resonance)-based Fcγ receptor antibody interaction kinetics, N-glycoprofiling with PNGase F digestion, 2-aminobenzoic acid labeling and high performance liquid chromatography and N-glycan analysis using capillary electrophoresis. In addition, we studied selected biological activity assays, such as complement-dependent cytotoxicity. The consistency and reproducibility of the assays are established by comparing the intra-day and inter-day assay results. Applications of the methodologies to address stability or changes in product characteristics are also reported. The study results reveal that the ch14.18 clinical product formulated in phosphate-buffered saline at a concentration of 5 mg/ml and stored at 2-8°C is stable for more than five years.

Computational Modeling on Concrete, Masonry and Fiber-reinforced Composites : Proceedings of the Workshop on 17 – 18 June 2009, Delft, The Netherlands

NARCIS (Netherlands)

Hendriks, M.A.N.; Billington, S.L.

2009-01-01

This booklet comprises the extended abstracts to be presented at the Ma(gni)FiCo workshop held in Delft, The Netherlands, on 17-18 June 2009. The spirit of this workshop is to have a small gathering with ample time for lively conversation and interaction among the student and faculty researchers. As

Troglitazone inhibits cell growth and induces apoptosis of B-cell acute lymphoblastic leukemia cells with t(14;18).

Science.gov (United States)

Takenokuchi, M; Saigo, K; Nakamachi, Y; Kawano, S; Hashimoto, M; Fujioka, T; Koizumi, T; Tatsumi, E; Kumagai, S

2006-01-01

Peroxisome proliferator-activated receptor-gamma (PPARgamma), a member of the nuclear receptor superfamily, has been detected in several human leukemia cells. Recent studies reported that PPARgamma ligands inhibit cell proliferation and induce apoptosis in both normal and malignant B-lineage cells. We investigated the expression of PPARgamma and the effects of PPARgamma ligands on UTree-O2, Bay91 and 380, three B-cell acute lymphoblastic leukemia (B-ALL) cell lines with t(14;18), which show a poor prognosis, accompanying c-myc abnormality. Western blot analysis identified expression of PPARgamma protein and real-time PCR that of PPARgamma mRNA on the three cell lines. Troglitazone (TGZ), a synthetic PPARgamma ligand, inhibited cell growth in these cell lines in a dose-dependent manner, which was associated with G(1) cell cycle arrest and apoptosis. We also found this effect PPARgamma independent since PPARgamma antagonists failed to reverse this effect. We assessed the expression of c-myc, an apoptosis-regulatory gene, since c-myc abnormality was detected in most B-ALL cells with t(14;18). TGZ was found to dose-dependently downregulate the expression of c-myc mRNA and c-myc protein in the three cell lines. These results suggest that TGZ inhibits cell growth via induction of G(1) cell cycle arrest and apoptosis in these cell lines and that TGZ-induced apoptosis, at least in part, may be related to the downregulation of c-myc expression. Moreover, the downregulation of c-myc expression by TGZ may depend on a PPARgamma-independent mechanism. Further studies indicate that PPARgamma ligands may serve as a therapeutic agent in B-ALL with t(14;18).

Implementation of synthetic aperture imaging on a hand-held device

DEFF Research Database (Denmark)

Hemmsen, Martin Christian; Kjeldsen, Thomas; Larsen, Lee

2014-01-01

-held devices all with different chipsets and a BK Medical UltraView 800 ultrasound scanner emulating a wireless probe. The wireless transmission is benchmarked using an imaging setup consisting of 269 scan lines x 1472 complex samples (1.58 MB pr. frame, 16 frames per second). The measured data throughput...... reached an average of 28.8 MB/s using a LG G2 mobile device, which is more than the required data throughput of 25.3 MB/s. Benchmarking the processing performance for B-mode imaging showed a total processing time of 18.9 ms (53 frames/s), which is less than the acquisition time (62.5 ms).......This paper presents several implementations of Syn- thetic Aperture Sequential Beamforming (SASB) on commer- cially available hand-held devices. The implementations include real-time wireless reception of ultrasound radio frequency sig- nals and GPU processing for B-mode imaging. The proposed...

55th Annual Canadian Society for Molecular Biosciences Conference on Epigenetics and Genomic Stability. Whistler, British Columbia, Canada, 14–18 March 2012.

Science.gov (United States)

Nelson, Christopher J; Ausió, Juan

2012-06-01

The 55th Annual Canadian Society for Molecular Biosciences Conference on Epigenetics and Genomic Stability in Whistler, Canada, 14-18 March 2012, brought together 31 speakers from different nationalities. The organizing committee, led by Jim Davie (Chair) at the University of Manitoba (Manitoba, Canada), consisted of several established researchers in the fields of chromatin and epigenetics from across Canada. The meeting was centered on the contribution of epigenetics to gene expression, DNA damage and repair, and the role of environmental factors. A few interesting talks on replication added some insightful information on the controversial issue of histone post-translational modifications as genuine epigenetic marks that are inherited through cell division.

18th International Congress on Project Management and Engineering

CERN Document Server

Blanco, José; Capuz-Rizo, Salvador

2016-01-01

This volume features papers from the 18th International Congress on Project Management and Engineering, held by the University of Zaragoza in collaboration with the Spanish Association of Project Management and Engineering (AEIPRO). It illustrates the state of the art in this emerging area. Readers will discover ways to increase the effectiveness of project engineering as well as the efficiency of project management. The papers, written by international researchers and professionals, cover civil engineering and urban planning, product and process engineering, environmental engineering, energy efficiency and renewable energies, rural development, safety, labor risks and ergonomics, and training in project engineering. Overall, this book contributes to the improvement of project engineering research and enhances the transfer of results to the job of project engineers and project managers around the world. It will appeal to all professionals in the field as well as researchers and teachers involved in the traini...

AdS{sub 3} holography for 1/4 and 1/8 BPS geometries

Energy Technology Data Exchange (ETDEWEB)

Giusto, Stefano [Dipartimento di Fisica ed Astronomia “Galileo Galilei”, Università di Padova,Via Marzolo 8, 35131 Padova (Italy); I.N.F.N. Sezione di Padova,Via Marzolo 8, 35131 Padova (Italy); Moscato, Emanuele; Russo, Rodolfo [Centre for Research in String Theory,School of Physics and Astronomy, Queen Mary University of London,Mile End Road, London, E1 4NS (United Kingdom)

2015-11-04

Recently a new class of 1/8-BPS regular geometries in type IIB string theory was constructed in arXiv:1503.01463. In this paper we provide a precise description of the semiclassical states dual, in the AdS/CFT sense, to these geometries. In explicit examples we show that the holographic 1-point functions and the Ryu-Takayanagi’s Entanglement Entropy for a single small interval match the corresponding CFT calculations performed by using the proposed dual states. We also discuss several new examples of such precision holography analysis in the 1/4-BPS sector and provide an explicit proof that the small interval derivation of the Entanglement Entropy used in arXiv:1405.6185 is fully covariant.

Development of dynamic models of wagons on models 18-9810 and 18-9855 bogies taking into account wheel wear research

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A. V. Saidova

2013-04-01

Full Text Available Purpose. Wear parameters clarification in wear simulation is an actual goal because of absence of corresponding data for freight cars in condition of using them on Russian railways. Research is devoted to development of dynamic models of wagons on three-peace two-axle models 18-9810 and 18-9855 bogies with maximum axle-loads 23,5 ts and 25 ts, and to choice of factors, with varying which parameters in the model of wheel wear can be identified. Methodology. The problem is solved by method of mathematic simulation in «MEDYNA» software. Wear calculation is based on abrasive wear theory (Archard’s theory. Findings. Clarification of wheels’ wear model may be done with varying of friction coefficient between wheel and rail for different wheel profile areas (flange and tread, wear coefficient in Archard’s model for mild and heavy wear and transition between them. Originality. Dynamic models of universal gondola on models 18-9810 and 18-9855 bogies are developed. It is established, that rail treads irregularities size effect wheel wear insignificantly, when car is running on circle track of constant radius. Practical value. Developed dynamic models of wagons on models 18-9810 and 18-9855 bogies may be used in wear simulation, determination of car running characteristics, interaction of car and rail of different type, construction, condition and etc. Research results of some factors influence on freight car wheel wear may be interesting for people, who study this problem.

The Second National Research Conference “History, Economics and Culture of the Medieval Turko-Tatar States of Western Siberia” (Kurgan, 17–18 April 2014

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D.N. Maslyuzhenko

2014-09-01

Full Text Available The article summarizes the results of the Second National Research Conference “History, Economics and Culture of the Medieval Turko-Tatar States of Western Siberia”, which was held in Kurgan on 17th–18th April 2014. 38 researchers from Russia, Kazakhstan, and Ukraine participated at the Conference. The Conference was focused on several topics. On the first day, the Conference started with the issues of the Shiban’s ulus history and a role of the Shibanids in the history of the Golden Horde, including the issue of the borders of these lands, the ulus of Jochi’s place in its administrative structure, the participation of representatives of the dynasty in the events of the Great Zamyatnya (i.e, the Great Distemper and strives of the 1420’s. There were also discussed the ethnic and political processes in the Tyumen and Siberian Yurt. Considerable attention was paid to the Turkization of the Western Siberian population and formation of various groups of the Siberian Tatars. Researchers have noted the limitations of the source base of the late-medieval history of the region and the need for a comprehensive approach to the research involving experts in the fields of history, archaeology, ethnography, anthropology, linguistics. A separate debate was held on the role of the Nogai and Bukhara factor in the history of the Kuchum Siberian khanate. On the second day, there were discussed various aspects of the Turkic-Tatar peoples’ occurrence from the Ural-Irtysh interfluve to the Russian State. There were presented reports both on the policy and destiny of the Kuchum descendants and legal and military aspects of the Tatar yurtes’ subordination. There was held a discussion about two versions of the Ichkinski Tatar ethnogenesis as a special group of the Tatar population of the region. Thereupon, the conference participants called for a cautious stance on the use of ethnic reconstructions in Turkic history and their use in the construction of

IAEA technical committee meeting on research using small fusion devices (abstracts)

International Nuclear Information System (INIS)

1999-12-01

The thirteenth IAEA technical committee meeting on research using small fusion devices are held in Chengdu, P. R. China on 18-20 Oct. , 1999. 41 articles are received and the content includes toroidal systems, helical systems, plasma focus, diagnostic systems, theory and modeling, improving confinement, numerical simulation, innovative concepts and others

ISVEE 14 Yucatan 2015 14th Symposium of the International Society for Veterinary Epidemiology and Economics.

Science.gov (United States)

de Anda, Jorge Hernández

2017-02-01

The 14th Symposium of the International Society for Veterinary Epidemiology and Economics (ISVEE 14) was held in Merida, Yucatan, Mexico during 3-7 November. 2015. The purpose of ISVEE 14 Yucatan 2015 was to provide a global forum for graduate students, postdoctoral fellows, junior and senior investigators, as well as health policymakers to exchange information that can advance the fields of veterinary epidemiology and economics, and other disciplines in the health and social sciences. The main theme of ISVEE 14 was Planning Our Future. Human population growth is predicted to increase nearly 50% to 11 billion by 2050, and climate change and changing land use can have an impact on local and global food systems, interactions among humans, wildlife and domestic animals, as well as local, regional, and global public health alerts. How can we help our systems of education, research, and public policy adapt? Are new veterinary graduates and epidemiology practitioners prepared to become active protagonists in the solution of health issues that affect humans and animal populations in a changing environment? What innovative research is needed to understand and enhance the food systems of the future? What are the expected roles or contributions of veterinarians or epidemiology practitioners on future climate change, food systems, and health? Is our profession or discipline leading One Health initiatives? Are there current or new models that make national veterinary services more efficacious and efficient for disease control and eradication? To help us answer these questions, the organizing committee of ISVEE 14 invited five distinguished keynote speakers to share their vision and innovative ideas on education, technological developments, research, and public policy of our future with a concentration in the following five areas: (i) One Health (Jonna Mazet), (ii) climate change (Bernard Bett), (iii) animal health economics (Jonathan Rushton), (iv) national veterinary services

Production of fluorine-18 from eithium carbonate in a research reactor

International Nuclear Information System (INIS)

Gasiglia, H.T.

1978-01-01

A method for the production of fluorine-18 in a research reactor, from irradiated lithium carbonate, is described. Fluorine-18 is separated from impurities in a alumina column, which is an appropriate procedure for its production as a carrier-free radioisotope for oral administration. Characteristics of the product, when fluorine is separated from irradiated target in an usual alumina column, are compared with those when fluorine is separated in a previously calcined(1000 0 C) alumina column: Yields of chemical separation and chemical forms of radioisotope obtained are studied. Fluorine elution is investigated for several eluant concentrations and the use of a lower concentrated eluant is emphasized. Purity degree of fluorine-18 solutions separated. A routine production procedure is determined by irradiating enriched lithium carbonate (95% 6 Li). Theoretical yields are compared with fluorine-18 production yields obtained in several irradiations [pt

6th International Workshop on Application of Lasers in Atomic Nuclei Research

CERN Document Server

Błaszczak, Z; Marinova, K; LASER 2004

2006-01-01

6th International Workshop on Application of Lasers in Atomic Nuclei Research, LASER 2004, held in Poznan, Poland, 24-27 May, 2004 Researchers and graduate students interested in the Mössbauer Effect and its applications will find this volume indispensable. The volume presents the most recent developments in the methodology of Mössbauer spectroscopy. Reprinted from Hyperfine Interactions (HYPE) Volume 162, 1-4

Total Synthesis of Four Stereoisomers of (4Z,7Z,10Z,12E,16Z,18E)-14,20-Dihydroxy-4,7,10,12,16,18-docosahexaenoic Acid and Their Anti-inflammatory Activities.

Science.gov (United States)

Goto, Tomomi; Urabe, Daisuke; Masuda, Koji; Isobe, Yosuke; Arita, Makoto; Inoue, Masayuki

2015-08-07

A novel anti-inflammatory lipid mediator, (4Z,7Z,10Z,12E,14S,16Z,18E,20R)-14,20-dihydroxy-4,7,10,12,16,18-docosahexaenoic acid (1aa), and its three C14,C20 stereoisomers (1ab,ba,bb) were synthesized in a convergent fashion. The carbon backbone of the target compounds was assembled from seven simple fragments by employing two Sonogashira coupling and three SN2 alkynylation reactions. The thus constructed four internal alkynes were chemoselectively reduced to the corresponding (Z)-alkenes by applying a newly developed stepwise protocol: (i) hydrogenation of the three alkynes using Lindlar catalyst and (ii) formation of the dicobalt hexacarbonyl complex from the remaining alkyne and subsequent reductive decomplexation. The synthetic preparation of the stereochemically defined four isomers 1aa,ab,ba,bb permitted determination of the absolute structure of the isolated natural product to be 1aa. Biological testing of the four synthetic 14,20-dihydroxydocosahexaenoic acids disclosed similar anti-inflammatory activities of the non-natural isomers (1ab,ba,bb) and the natural form (1aa).

The Trojan Horse Method as a tool to investigate low-energy resonances: the 18O(p, α)15N and 17O(p, α)14N cases

International Nuclear Information System (INIS)

La Cognata, M.; Sergi, M. L.; Spitaleri, C.; Cherubini, S.; Gulino, M.; Kiss, G.; Lamia, L.; Pizzone, R. G.; Romano, S.; Mukhamedzhanov, A.; Goldberg, V.; Tribble, R.; Coc, A.; Hammache, F.; Sereville, N. de; Irgaziev, B.; Tumino, A.

2010-01-01

The 18 O(p, α) 15 N and 17 O(p, α) 14 N reactions are of primary importance in several as-trophysical scenarios, including nucleosynthesis inside Asymptotic Giant Branch stars and oxygen and nitrogen isotopic ratios in meteorite grains. They are also key reactions to understand exotic systems such as R-Coronae Borealis stars and novae. Thus, the measurement of their cross sections in the low energy region can be crucial to reduce the nuclear uncertainty on theoretical predictions, because the resonance parameters are poorly determined. The Trojan Horse Method, in its newly developed form particularly suited to investigate low-energy resonances, has been applied to the 2 H( 18 O, α 15 N)n and 2 H( 17 O, α 14 N)n reactions to deduce the 18 O(p, α) 15 N and 17 O(p, α) 14 N cross sections at low energies. Resonances in the 18 O(p, α) 15 N and 17 O(p, α) 14 N excitation functions have been studied and the resonance parameters deduced.

Operational Research : Congress of APDIO, the Portuguese Operational Research Society

CERN Document Server

Almeida, João; Oliveira, José; Pinto, Alberto

2018-01-01

This proceedings book presents selected contributions from the XVIII Congress of APDIO (the Portuguese Association of Operational Research) held in Valença on June 28–30, 2017. Prepared by leading Portuguese and international researchers in the field of operations research, it covers a wide range of complex real-world applications of operations research methods using recent theoretical techniques, in order to narrow the gap between academic research and practical applications. Of particular interest are the applications of, nonlinear and mixed-integer programming, data envelopment analysis, clustering techniques, hybrid heuristics, supply chain management, and lot sizing and job scheduling problems. In most chapters, the problems, methods and methodologies described are complemented by supporting figures, tables and algorithms.   The XVIII Congress of APDIO marked the 18th installment of the regular biannual meetings of APDIO – the Portuguese Association of Operational Research. The meetings bring toget...

A leukemic double-hit follicular lymphoma associated with a complex variant translocation, t(8;14;18)(q24;q32;q21), involving BCL2, MYC, and IGH.

Science.gov (United States)

Minakata, Daisuke; Sato, Kazuya; Ikeda, Takashi; Toda, Yumiko; Ito, Shoko; Mashima, Kiyomi; Umino, Kento; Nakano, Hirofumi; Yamasaki, Ryoko; Morita, Kaoru; Kawasaki, Yasufumi; Sugimoto, Miyuki; Yamamoto, Chihiro; Ashizawa, Masahiro; Hatano, Kaoru; Oh, Iekuni; Fujiwara, Shin-Ichiro; Ohmine, Ken; Kawata, Hirotoshi; Muroi, Kazuo; Miura, Ikuo; Kanda, Yoshinobu

2018-01-01

Double-hit lymphoma (DHL) is defined as lymphoma with concurrent BCL2 and MYC translocations. While the most common histological subtype of DHL is diffuse large B-cell lymphoma, the present patient had leukemic follicular lymphoma (FL). A 52-year-old man was admitted to our hospital due to general fatigue and cervical and inguinal lymph node swelling. The patient was leukemic and the pathological diagnosis of the inguinal lymph node was FL grade 1. Chromosomal analysis revealed a complex karyotype including a rare three-way translocation t(8;14;18)(q24;q32;q21) involving the BCL2, MYC, and IGH genes. Based on a combination of fluorescence in situ hybridization (FISH), using BCL2, MYC and IGH, and spectral karyotyping (SKY), the karyotype was interpreted as being the result of a multistep mechanism in which the precursor B-cell gained t(14;18) in the bone marrow and acquired a translocation between der(14)t(14;18) and chromosome 8 in the germinal center, resulting in t(8;14;18). The pathological diagnosis was consistently FL, not only at presentation but even after a second relapse. The patient responded well to standard chemotherapies but relapsed after a short remission. This patient is a unique case of leukemic DH-FL with t(8;14;18) that remained in FL even at a second relapse. Copyright © 2017 Elsevier Inc. All rights reserved.

Proceedings of the 1998 workshop on the utilization of research reactors

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-10-01

The 1998 Workshop on the Utilization of Research Reactors, which is the seventh Workshop on the theme of research reactor utilization was held in Yogyakarta and Serpong, Indonesia from February 8 to 14. This Workshop was executed based on the agreement in the Ninth International Conference for Nuclear Cooperation in Asia (ICNCA) held in Tokyo, March 1998. The whole Workshop consists of the Workshop on the theme of following three fields, 1) Neutron Scattering, 2) Neutron Activation analysis and 3) Safe Operation and Maintenance of Research Reactor, and the Sub-workshop carried out the experiment of Neutron Activation analysis. The total number of participants for the workshop was about 100 people from 8 countries, i.e. Australia, China, Indonesia, Korea, Malaysia, Thailand, Vietnam and Japan. The 38 papers are indexed individually. (J.P.N.)

EUFOREA Rhinology Research Forum 2016: report of the brainstorming sessions on needs and priorities in rhinitis and rhinosinusitis

NARCIS (Netherlands)

Hellings, P. W.; Akdis, C. A.; Bachert, C.; Bousquet, J.; Pugin, B.; Adriaensen, G.; Advani, R.; Agache, I.; Anjo, C.; Anmolsingh, R.; Annoni, E.; Bieber, T.; Bizaki, A.; Braverman, I.; Callebaut, I.; Castillo Vizuete, J. A.; Chalermwatanachai, T.; Chmielewski, R.; Cingi, C.; Cools, L.; Coppije, C.; Cornet, M. E.; de Boeck, I.; de Corso, E.; de Greve, G.; Doulaptsi, M.; Edmiston, R.; Erskine, S.; Gevaert, E.; Gevaert, P.; Golebski, K.; Hopkins, C.; Hox, V.; Jaeggi, C.; Joos, G.; Khwaja, S.; Kjeldsen, A.; Klimek, L.; Koennecke, M.; Kortekaas Krohn, I.; Krysko, O.; Kumar, B. N.; Langdon, C.; Lange, B.; Lekakis, G.; Levie, P.; Lourijsen, E.; Lund, V. J.; Martens, K.; Mő Sges, R.; Mullol, J.; Nyembue, T. D.; Palkonen, S.; Philpott, C.; Pimentel, J.; Poirrier, A.; Pratas, A. C.; Prokopakis, E.; Pujols, L.; Rombaux, P.; Schmidt-Weber, C.; Segboer, C.; Spacova, I.; Staikuniene, J.; Steelant, B.; Steinsvik, E. A.; Teufelberger, A.; van Gerven, L.; van Gool, K.; Verbrugge, R.; Verhaeghe, B.; Virkkula, P.; Vlaminck, S.; Vries-Uss, E.; Wagenmann, M.; Zuberbier, T.; Seys, S. F.; Fokkens, W. J.

2017-01-01

The first European Rhinology Research Forum organized by the European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) was held in the Royal Academy of Medicine in Brussels on 17th and 18th November 2016, in collaboration with the European Rhinologic Society (ERS) and the

[National health research systems in Latin America: a 14-country review].

Science.gov (United States)

Alger, Jackeline; Becerra-Posada, Francisco; Kennedy, Andrew; Martinelli, Elena; Cuervo, Luis Gabriel

2009-11-01

This article discusses the main features of the national health research systems (NHRS) of Argentina, Bolivia, Brazil, Chile, Costa Rica, Cuba, Ecuador, El Salvador, Honduras, Panama, Paraguay, Peru, Uruguay, and Venezuela, based on documents prepared by their country experts who participated in the First Latin American Conference on Research and Innovation for Health held in April 2008, in Rio de Janeiro, Brazil. The review also includes sources cited in the reports, published scientific papers, and expert opinion, as well as regional secondary sources. Six countries reported having formal entities for health research governance and management: Brazil and Costa Rica's entities are led by their ministries of health; while Argentina, Cuba, Ecuador, and Venezuela have entities shared by their ministries of health and ministries of science and technology. Brazil and Ecuador each reported having a comprehensive national policy devoted specifically to health science, technology, and innovation. Argentina, Brazil, Costa Rica, Cuba, Ecuador, Panama, Paraguay, Peru, and Venezuela reported having established health research priorities. In conclusion, encouraging progress has been made, despite the structural and functional heterogeneity of the study countries' NHRS and their disparate levels of development. Instituting good NHRS governance/management is of utmost importance to how efficiently ministries of health, other government players, and society-at-large can tackle health research.

Proceedings of the 18th Annual Conference on Fossil Energy Materials.

Energy Technology Data Exchange (ETDEWEB)

Judkins, RR

2004-11-02

The 18th Annual conference on Fossil Energy Materials was held in Knoxville, Tennessee, on June 2 through June 4, 2004. The meeting was sponsored by the U.S. Department of Energy's (DOE) Office of Fossil Energy through the Advanced Research Materials Program (ARM). The objective of the ARM Program is to conduct research and development on materials for longer-term fossil energy applications, as well as for generic needs of various fossil fuel technologies. The management of the program has been decentralized to the DOE Oak Ridge Operations Office and Oak Ridge National Laboratory (ORNL). The research is performed by staff members at ORNL and by researchers at other national laboratories, universities, and in private industry. The work is divided into the following categories: (1) structural, ceramics, (2) new alloys and coatings, (3) functional materials, and (4) technology development and transfer.

16 CFR 14.12 - Use of secret coding in marketing research.

Science.gov (United States)

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Use of secret coding in marketing research... STATEMENTS § 14.12 Use of secret coding in marketing research. (a) The Federal Trade Commission has determined to close its industry-wide investigation of marketing research firms that was initiated in...

Proceedings of the Annual Meeting, Aquatic Plant Control Research Program (18th) Held at Raleigh, North Carolina on 14-17 November 1983.

Science.gov (United States)

1984-06-01

can reproduce by a variety of vegetative methods. It is also capable of sexual reproduction by seeds, but staminate flowers are rare and reproduction...cultures used as inocula were grown in 0.25 percent Pectin ne(tiu m. The cells were harvested by centrifugation and resuspended in sterile normal...saline. The viable cells were counted on both N A and PA. 0 • l niv’ersitv of Massachusetts. Arnherst, May- )1t. \\Wih Ol ;11:11it I);0i(ol 1f Yulihana

Commercial products and services of research reactors. Proceedings of a technical meeting held in Vienna 28 June - 2 July 2010

International Nuclear Information System (INIS)

2013-07-01

Although the number of operational research reactors is steadily decreasing, more than half of those that remain are greatly underutilized and, in most cases, underfunded. To continue to play a key role in the development of peaceful uses of nuclear technology, the remaining research reactors will need to provide useful products and services to private, national and regional customers, in some cases with adequate revenue generation for reliable, safe and secure facility management and operation. In the light of declining governmental financial support and the need for improved physical security and conversion to low enriched uranium (LEU) fuel, many research reactors have been challenged to generate income to offset increasing operational and maintenance costs. The renewed interest in nuclear power (and therefore in nuclear education and training), the global expansion of diagnostic and therapeutic nuclear medicine, and the extensive use of semiconductors in electronics and in other areas have created new opportunities for research reactors, prominent among them, markets for products and services in regions and countries without such facilities. It is clear that such initiatives towards greater self-reliance will need to address such aspects as market surveys, marketing and business plans, and cost of delivery services. It will also be important to better inform present and future potential end users of research reactor services of the capabilities and products that can be provided. This publication is a compilation of material from an IAEA technical meeting on 'Commercial Products and Services of Research Reactors', held in Vienna, Austria, from 28 June to 2 July 2010. The overall objective of the meeting was to exchange information on good practices and to provide concrete examples, in technical presentations and brainstorming discussions, to promote and facilitate the development of commercial applications of research reactors. The meeting also aimed to enhance

The 18th Annual Conference on Finance and Accounting

OpenAIRE

YEŞİLÇELEBİ, Gül

2017-01-01

Abstract. In this paper, the evaluation of the 18th Annual Conference on Finance and Accounting held on 26 May 2017 in Prague, Czech Republic will be mentioned.Keywords. Accounting, Finance, Czech Republic.JEL. M40, G10.

Gilding Techniques in Religious Art Between East and West, 14th -18th Centuries

Directory of Open Access Journals (Sweden)

I.C.A. Sandu

2010-03-01

Full Text Available The paper proposes a short review on gilding techniques and materials from artifacts of religious heritage between 14th and 18th centuries, mainly gilt wood and gilded panel paintings. The study underlines the main aspects related to the use of certain materials and application techniques in different countries and époques, between Eastern and Western Europe, exemplifying with case studies of real gilded objects from Romanian, Greek, Russian and Portuguese ecclesiastic heritage. The contribution of some analytical techniques, such as optical, scanning electron and atomic force microscopies (OM, SEM, AFM, XRF and EDX spectroscopic analysis to the study of these objects is emphasized as well as the peculiarities of the obtained information.

Physical Research Laboratory radiocarbon 14C dates : CS-I

International Nuclear Information System (INIS)

Agrawal, D.P.; Krishnamurthy, R.V.; Kusumgar, Sheela; Pant, R.K.

1978-01-01

The 14 C dates of archaeological samples measured at the Radiocarbon Laboratory of the Physical Research Laboratory, Ahmedabad are presented. Samples were converted into methane and measured in gas proportional counters. Ninety-five percent activity of NBS oxalic acid was used as modern standard. The dates in years B.P. are given for each sample based on the half-life values of 5568 +- 30 years and 5730 +- 40 years, the latter within parenthesis. The dates are not calibrated for 14 C/ 12 C variations. To convert the dates into AD/BC scale, 1950 AD should be used as reference year. A number of 14 C dates (PRL-81, -83, -67, -68) now confirm that the Painted Grey Ware culture extended upto the 3rd century BC. Some of the dates from Barkhera (PRL-113), Bateshwar (PRL-200), Bhimbetka (PRL-17) and Koldihawa (PRL-100, 101) are older than normally expected, probably indicative of some hitherto unknown basal cultures in these regions. 14 C dates on in situ Megalithic materials do not seem to go beyond 200 BC. (author)

Sixth Conference on China-ASEAN People-to-People Friendship Organizations Held in Bangkok

Institute of Scientific and Technical Information of China (English)

2011-01-01

<正>With the theme of "Opportunities and Challenges of China-ASEAN Friendly Cooperation", the Sixth Conference on China-ASEAN People-to-People Friendship Organizations organized by the Thai-Chinese Friendship Association was held in Bangkok August 18 and 19. A delegation of China-ASEAN Association led by its president Gu Xiulian joined about 200 representatives from friendship-with-China organizations in 10 ASEAN countries.

Direct activation of EXPANSIN14 by LBD18 in the gene regulatory network of lateral root formation in Arabidopsis.

Science.gov (United States)

Kim, Jungmook; Lee, Han Woo

2013-02-01

Root system architecture is important for plants to adapt to a changing environment. The major determinant of the root system is lateral roots originating from the primary root. The developmental process of lateral root formation can be divided into priming, initiation, primordium development and the emergence of lateral roots, and is well characterized in Arabidopsis. The hormone auxin plays a critical role in lateral root development, and several auxin response modules involving AUXIN RESPONSE FACTORS (ARFs), transcriptional regulators of auxin-regulated genes and Aux/IAA, negative regulators of ARFs, regulate lateral root formation. The LATERAL ORGAN BOUNDARIES DOMAIN/ASYMMETRIC LEAVES2-LIKE (LBD/ASL) gene family encodes a unique class of transcription factors harbouring a conserved plant-specific lateral organ boundary domain and plays a role in lateral organ development of plants including lateral root formation. In our previous study, we showed that LBD18 stimulates lateral root formation in combination with LBD16 downstream of ARF7 and ARF19 during the auxin response. We have recently demonstrated that LBD18 activates expression of EXP14, a gene encoding the cell-wall loosening factor, by directly binding to the EXP14 promoter to promote lateral root emergence. Here we present the molecular function of LBD18 and its gene regulatory network during lateral root formation.

Educational Reform and Educational Research: New Challenges in Linking Research, Information and Decision Making. Final Report of the International Meeting (Tokyo, Japan, September 4-14, 1995).

Science.gov (United States)

National Inst. for Educational Research, Tokyo (Japan).

This document summarizes proceedings of a meeting held in September 1995. The purpose of the meeting was to gather educators and policymakers in order to establish criteria concerning links between educational research and decision making. Twenty participants from the following countries attended: Argentina, Australia, Bahrain, Botswana, Brazil,…

EUFOREA Rhinology Research Forum 2016

DEFF Research Database (Denmark)

Hellings, P W; Akdis, C A; Bachert, C

2017-01-01

The first European Rhinology Research Forum organized by the European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) was held in the Royal Academy of Medicine in Brussels on 17th and 18th November 2016, in collaboration with the European Rhinologic Society (ERS......) and the Global Allergy and Asthma European Network (GA2LEN). One hundred and thirty participants (medical doctors from different specialties, researchers, as well as patients and industry representatives) from 27 countries took part in the multiple perspective discussions including brainstorming sessions on care...... pathways and research needs in rhinitis and rhinosinusitis. The debates started with an overview of the current state of the art, including weaknesses and strengths of the current practices, followed by the identification of essential research needs, thoroughly integrated in the context of Precision...

Computer supported qualitative research

CERN Document Server

Reis, Luís; Sousa, Francislê; Moreira, António; Lamas, David

2017-01-01

This book contains an edited selection of the papers accepted for presentation and discussion at the first International Symposium on Qualitative Research (ISQR2016), held in Porto, Portugal, July 12th-14th, 2016. The book and the symposium features the four main application fields Education, Health, Social Sciences and Engineering and Technology and seven main subjects: Rationale and Paradigms of Qualitative Research (theoretical studies, critical reflection about epistemological dimensions, ontological and axiological); Systematization of approaches with Qualitative Studies (literature review, integrating results, aggregation studies, meta -analysis, meta- analysis of qualitative meta- synthesis, meta- ethnography); Qualitative and Mixed Methods Research (emphasis in research processes that build on mixed methodologies but with priority to qualitative approaches); Data Analysis Types (content analysis , discourse analysis , thematic analysis , narrative analysis , etc.); Innovative processes of Qualitative ...

14 CFR 77.41 - Scope.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Scope. 77.41 Section 77.41 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE OBJECTS... applies to hearings held by the FAA under titles I, III, and X of the Federal Aviation Act of 1958 (49 U.S...

Web-Based Instruction and Learning: Responding to K-14 Customer Needs

Science.gov (United States)

McCarthy, Marianne; Grabowski, Barbara; Koszalka, Tiffany; Peck, Christa

2003-01-01

A follow-up working conference was held at Lewis Research Center (now Glenn Research Center) on September 23-25, 1997, to continue discussing issues related to the development of Web-based education materials for the K-14 community. The conference continued the collaboration among the NASA aerospace technology Centers (Ames, Dryden, Langley, and Lewis [now Glenn]), NASA Headquarters, the University of Idaho and the Pennsylvania State University. The conference consisted of presentations by the Aeronautics Cooperative Agreement teams, and working sessions that addressed issues related to the conference theme, responding to the K-14 customers needs. The group identified the most significant issues by consensus. The issues addressed were: classroom access, World Wide Web resources, teacher training, different teaching and learning styles, interactivity, and education standards. The working sessions produced observations and recommendations in each of these areas in order to work toward the goal of making NASA sponsored Web-based educational resources useful to teachers and students.

Rice breeding with induced mutations II. Report of an FAO/IAEA research co-ordination meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

1970-03-01

This report contains the proceedings of the fourth meeting of participants in the FAO/IAEA Co-ordinated Program of Research on the Use of Induced Mutations in Rice Breeding, a program which was initiated in 1964. The three previous meetings were reported as follows: First: proceedings published in the International Rice Commission Newsletter, Vol. XV, No. 1 (1966). Second: report presented to the IRC Working Party meeting at Lake Charles, Louisiana, 18-30 July 1966. Third: proceedings published by the IAEA as Technical Reports Series No. 86 under the title 'Rice breeding with induced mutations'. The fourth meeting was held at Oiso, Japan, on 12-14 August 1968. Co-operators from nine countries attended, together with scientists from five other countries, the International Rice Research Institute, the Rockefeller Foundation, the International Rice Commission, and the FAO and IAEA. In addition, a number of scientists from the host country were present. The purpose of the meeting was to present reports on research related to or carried out under the co-ordinated program in 1967/68, to review and co-ordinate research plans for 1968/69, and to draw up technical recommendations for future work.

Interaction of actinide ions with [NaP5W30O110]14- and [P2W18O62]6-

International Nuclear Information System (INIS)

Choppin, G.R.; Wall, D.E.

2003-01-01

Stability constants (log β 101 ) of Th 4+ , UO 2 2+ , NpO 2 + and Am 3+ with [NaP 5 W 30 O 110 ] 14- were determined by solvent extraction (μ = 0.1M NaCl) and found to be 6.18 ± 0.07, 3.80 ± 0.06, 2.98 ± 0.04, and 5.85 ± 0.05, respectively. The order of stability constants: Th 4+ > Am 3+ > UO 2 2+ > NpO 2 + is due to electrostatic repulsion between the actinyl oxygens and oxygens on the polyoxometalate surface. The order of stability constants for metal complexes with [P 2 W 18 O 62 ] 6- is Th 4+ > UO 2 2+ > Eu 3+ >NpO 2 + because the steric repulsion between actinyl oxygens and oxygens on polyoxometalate are less important. Enthalpies of complexation were measured by calorimetric titration of Th 4+ , UO 2 2+ , Nd 3+ with [NaP 5 W 30 O 110 ] 14- and [P 2 W 18 O 62 ] 6- . The results indicate that the conformation and charge distribution of the microscopic surface structures are important factors in the formation of pseudocolloids. (author)

Synthesis of 2-Phenylazonaphtho[1,8-ef][1,4]diazepines and 9-(3-Arylhydrazonopyrrolo[1,2-a]perimidines as Antitumor Agents

Directory of Open Access Journals (Sweden)

Thoraya A. Farghaly

2014-01-01

Full Text Available Two series of naphtho[1,8-ef][1,4]diazepines and pyrrolo[1,2-a]perimidines were prepared starting from 1,8-diaminonaphthalene and hydrazonoyl chlorides. The structures of the products were determined on the basis of their spectral data and elemental analyses. The mechanism of formation of such products was also discussed. The prepared compounds were screened for their antitumor activity against three cell lines, namely, MCF-7, TK-10 and UACC-62, and some derivatives showed promising activity.

The 14th International Workshops on Opportunistic Protists (IWOP 14).

Science.gov (United States)

Cushion, Melanie T; Limper, Andrew H; Porollo, Aleksey; Saper, Vivian E; Sinai, Anthony P; Weiss, Louis M

2018-05-03

The 14th International Workshops on Opportunistic Protists (IWOP-14) was held August 10-12, 2017 in Cincinnati, OH, USA. The IWOP meetings focus on opportunistic protists (OIs); for example, free-living amoebae, Pneumocystis spp., Cryptosporidium spp., Toxoplasma, the Microsporidia, and kinetoplastid flagellates. The highlights of Pneumocystis spp. research included the reports of primary homothallism for mating; a potential requirement for sexual replication in its life cycle; a new antigen on the surface of small asci; roles for CLRs, Dectin-1, and Mincle in host responses; and identification of MSG families and mechanisms used for surface variation. Studies of Cryptosporidia spp. included comparative genomics, a new cryopreservation method; the role of mucin in attachment and invasion, and epidemiological surveys illustrating species diversity in animals. One of the five identified proteins in the polar tube of Microsporidia, PTP4, was shown to play a role in host infection. Zebrafish were used as a low cost vertebrate animal model for an evaluation of potential anti-toxoplasma drugs. Folk medicine compounds with anti-toxoplasma activity were presented, and reports on the chronic toxoplasma infection provided evidence for increased tractability for the study of this difficult life cycle stage. Escape from the parasitophorus vacuole and cell cycle regulation were the topics of the study in the acute phase. © 2018 International Society of Protistologists.

NEUTRON-PROTON ANALYZING POWER DATA AT 7.6, 12.0, 14.1, 16.0, 18.5 MeV

OpenAIRE

Weisel , G.; Tornow , W.; Howell , C.; Felsher , P.; Alohali , M.; Chen , Z.; Walter , R.; Lambert , J.; Treado , P.

1990-01-01

Neutron-Proton Ay(θ) measurements have been made at 7.6, 12.0, 14.1, 16.0, and 18.5 MeV. A sensitivity study establishes the importance of Ay(θ) in determining the 3P0, 1, 2 phase shifts in n-p scattering. The data are compared to the predictions of two phase-shift studies (one of which incorporates CIB effects), and the Paris and Bonn NN potenials.

Report of the Fourth international workshop on human chromosome 18 mapping 1996

International Nuclear Information System (INIS)

Silverman, G.A.; Overhauser, J.; Gerken, S.; Aburomia, R.; O'Connell, P.; Krauter, K.S.; Detera-Wadleigh, S.D.; Yoshikawa, T.; Collins, A.R.; Geurts van Kessel, A.

1996-01-01

The fourth international workshop on human chromosome 18 mapping was held in Boston, Massachusetts, USA on October 7-9, 1996. The workshop was attended by 34 participants from 7 countries. The goals of the workshop were to (1) generate integrated genetic and physical maps, (2) update the transcriptional map, (3) assess the syntenic relationships between human chromosome 18 and the mouse genome, and (4) establish a chromosome 18 web site

Reading Research in the Socialist Countries. Abridged Papers and Minutes of a Conference (Budapest, Hungary, October 15-18, 1974).

Science.gov (United States)

Dobrinina, Natalia Y., Ed.; And Others

These papers on reading research in the socialist countries were delivered at a conference held in Budapest, Hungary, in October of 1974. Included are the text of the introductory address and papers on the following topics: (1) the library and society; (2) the library as it relates to students, teachers, and engineers; (3) the role and…

Project Management and sustainability - review of the 4th IPMA Research Conference 2016

Directory of Open Access Journals (Sweden)

Helgi Thor Ingason

2017-06-01

Full Text Available The 4th IPMA research conference was held on Project Management and Sustainability in Reykjavik, Iceland from September 14th - 16th 2016. In this article, we give a general outline of the structure of the conference, the main findings and what they mean for the project management community.

Synthesis of C-9-14C-1,8-dihydroxy-3-carboxyanthraquinone

International Nuclear Information System (INIS)

De Witte, P.; Lemli, J.

1988-01-01

The synthesis of C-9- 14 C-rhein is reported using 14 CO 2 as a 14 C-source. After preparing 14 C-1, 8-dimethoxy-3-methylanthraquinone by a condensation reaction, the product is demethylated and the 3-methyl group converted to the corresponding 3-carboxy group. The radio-active yield of the total synthesis, starting with 1 Ci 14 CO 2 is 6,9% (6, 9 mCi); 352 mg 14 rhein is produced with a specific activity of 55,7 mCi/mmol. (author)

18th Workshop on Crystalline Silicon Solar Cells and Modules: Materials and Processes; Workshop Proceedings, 3-6 August 2008, Vail, Colorado

Energy Technology Data Exchange (ETDEWEB)

Sopori, B. L.

2008-09-01

The National Center for Photovoltaics sponsored the 18th Workshop on Crystalline Silicon Solar Cells & Modules: Materials and Processes, held in Vail, CO, August 3-6, 2008. This meeting provided a forum for an informal exchange of technical and scientific information between international researchers in the photovoltaic and relevant non-photovoltaic fields. The theme of this year's meeting was 'New Directions for Rapidly Growing Silicon Technologies.'

Use of neutron beams for low and medium flux research reactors: Radiography and materials characterization. Report of a technical committee held in Vienna, 4-7 May 1993

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-10-01

The present report is the result of the Technical Committee meeting held during 4-7 May 1993 in Vienna, Austria, and includes contributions from the participants. The Physics Section of the Department of Research and Isotopes was responsible for the co-ordination and compilation of the report. The report is intended to provide guidelines to research reactor owners and operators for promoting and developing their research programmes and industrial applications for neutron radiology, related neutron inspection and analytical techniques and neutron beam irradiation. Refs, figs and tabs.

Use of neutron beams for low and medium flux research reactors: Radiography and materials characterization. Report of a technical committee held in Vienna, 4-7 May 1993

International Nuclear Information System (INIS)

1995-10-01

The present report is the result of the Technical Committee meeting held during 4-7 May 1993 in Vienna, Austria, and includes contributions from the participants. The Physics Section of the Department of Research and Isotopes was responsible for the co-ordination and compilation of the report. The report is intended to provide guidelines to research reactor owners and operators for promoting and developing their research programmes and industrial applications for neutron radiology, related neutron inspection and analytical techniques and neutron beam irradiation. Refs, figs and tabs

PIXE analysis of Moroccan architectural glazed ceramics of 14th-18th centuries

International Nuclear Information System (INIS)

Zucchiatti, A.; Azzou, A.; El Amraoui, M.; Haddad, M.; Bejjit, L.; Ait Lyazidi, S.

2009-01-01

The PIXE analysis of glazes and ceramic bodies of a set of architectural glazed ceramics (mostly the zellige mosaics), sampled from seven Moroccan monuments from the 14th to the 18th century AD, has been performed. We have identified high lead glazes, opacified with tin-oxide, laid over a calciferous body to produce hard tiles easy to chisel as required by the zellige technique. The analysis has revealed significant differences between the monuments examined: in particular in the formulation of the base glass and in the use of stains to produce coloured glazes. We observed the peculiarity of materials used in Marrakech and we could distinguish, both in terms of glazes and ceramic bodies, the two almost contemporary Madersas dedicated to the sultan Bou Inan, one in Meknes the other in Fez. The PIXE measurements integrate a broad range of spectrometric investigations performed in the past few years. (author)

Abstracts of the international scientific-practical conference on space research, technology and conversion-II

International Nuclear Information System (INIS)

1997-04-01

The International Conference on space research, technology and conversion-II was held on 16-18 April, 1997 in Tashkent, Uzbekistan. The specialists discussed various aspects of space research, technology and conversion problems. More than 60 talks were presented in the meeting on the following subjects: remote sensing and the processing of satellite information; space navigation and others, including radiation effects in silicon solar cells caused by cosmic radiation. (A.A.D.)

CLIC/ILC Researchers Explore New Avenues for Collaboration

CERN Multimedia

Katarina Anthony

2010-01-01

Researchers from CLIC and ILC met for their first common International Workshop on Linear Colliders, which was held in Geneva from 18 to 22 October. Although the talks were mostly scientific and technical, the political message behind them was a breakthrough, as the workshop showed the progress made in unifying the two communities.   The International Workshop on Linear Colliders (IWLC), which was organised by the European Committee for Future Accelerators, hosted by CERN, and held at CERN and the International Conference Centre in Geneva, attracted a large audience of about 500 experts. Although there have been other joint conferences between the CLIC and ILC communities before, they have all been focused on specific technical and/or managerial issues. The IWLC was part of an ongoing effort by CLIC and ILC to provide an environment in which researchers can exchange ideas, inform their peers about their most recent achievements and work together on common issues. Given the possible technical ov...

Neutron-proton analyzing power data at 7.6, 12.0, 14.1, 16.0, 18.5 MeV

International Nuclear Information System (INIS)

Weisel, G.J.; Tornow, W.; Howell, C.R.; Felsher, P.D.; Alohali, M.; Chen, Z.P.; Walter, R.L.; Lambert, J.M.; Treado, P.A.

1990-01-01

Neutron-Proton A y (θ) measurements have been made at 7.6, 12.0, 14.1, 16.0, and 18.5 MeV. A sensitivity study establishes the importance of A y (θ) in determining the 3 P 0,1,2 phase shifts in n-p scattering. The data are compared to the predictions of two phase-shift studies (one of which incorporates CIB effects), and the Paris and Bonn NN potentials

Neutron data compilation. Report of a Panel sponsored by the International Atomic Energy Agency and held in Brookhaven, 10-14 February 1969

Energy Technology Data Exchange (ETDEWEB)

NONE

1969-02-15

The IAEA organized and convened a Panel on Neutron Data Compilation. This Panel was organized by the Agency following the recommendations made by the International Nuclear Data Committee (INDC) which agreed that a general review of world neutron data compilation activities was desirable. In this context neutron data compilation encompasses the collection, storage and dissemination of bibliographic information and of qualitative and numerical data on the interaction of neutrons with nuclei and atoms for all incident energies. Such information and data have important applications in low energy neutron physics and many important. areas of nuclear technology. The principal objective of the Panel on Neutron Data Compilation, Which was held at Brookhaven National Laboratory during 10-14 February 1969, was to review how the world's principal data centers located at Brookhaven, Saclay, Obninsk and Vienna could ideally meet the demands and needs of experimental and theoretical neutron physicists, evaluators, reactor physicists as well as other existing and potential users. Fourteen papers were considered during formal sessions of the Panel and are reported on the following pages. The members of the Panel separated into five working groups to consider specific terms of references and make recommendations. Their reports were discussed.

Employment and work safety among 12 to 14 year olds: listening to parents.

Science.gov (United States)

Usher, Amelia M; Breslin, Curtis; MacEachen, Ellen; Koehoorn, Mieke; Laberge, Marie; Laberge, Luc; Ledoux, Élise; Wong, Imelda

2014-10-01

Survey research indicates that a surprising number of 12 to 14 year olds in North America engage in some form of paid work, and work-related injuries for this age group are reported at rates similar to older teens. Parents exhibit significant involvement in many aspects of their teens' work and may influence perceptions of work safety, yet few studies have explored this phenomenon from a qualitative perspective with parents of working 12 to 14 year olds. This paper focuses on parental perceptions and understandings of work safety based on focus groups conducted with urban Canadian parents of young teens who work for pay. Parents discussed the types of job held by their 12 to 14 year olds, the perceived costs and benefits to working at this age, and their understanding of risk and supervision on the job. A grounded theory approach was used to thematically analyze the focus group transcripts. Parents in this study held favourable attitudes towards their 12 to 14 year olds' working. Parents linked pro-social moral values and skills such as responsibility, work ethic, time management, and financial literacy with their young teen's employment experience. Risks and drawbacks were generally downplayed or discounted. Perceptions of workplace safety were mitigated by themes of trust, familiarity, sense of being in control and having discretion over their 12 to 14 year olds' work situation. Further, parental supervision and monitoring fell along a continuum, from full parental responsibility for monitoring to complete trust and delegation of supervision to the workplace. The findings suggest that positive parental attitudes towards working overshadow occupational health and safety concerns. Parents may discount potential hazards based on the presence of certain mitigating factors.

Conference proceedings for cooperative research program for safety evaluation methods of concrete nuclear structures held at Skokie, Illinois on November 20, 1980

International Nuclear Information System (INIS)

Oesterle, R.G.; Russell, H.G.

1981-07-01

A meeting to discuss a cooperative research program was held on November 20, 1980, in Skokie, Illinois, at the headquarters of the Construction Technology Laboratories of the Portland Cement Association. This meeting was jointly sponsored by the U.S. Nuclear Regulatory Commission and the Portland Cement Association. Representatives from the Nuclear Regulatory Commission, electric utility companies, architecture-engineering companies, construction companies, Electric Power Research Institute, and organizations currently performing NRC sponsored research attended. The first part of the meeting was devoted to presentations of results of research sponsored by the Nuclear Regulatory Commission. In addition, presentations describing construction problems currently resulting from existing design requirements were made. The second part of the meeting was devoted to a presentation of a proposed cooperative program to expand the scope of previous research work. A considerable amount of discussion resulted from the presentations. The purpose of this report is to present a transcript of the presentations and discussions during the meeting. It is anticipated that the report will contribute to a better understanding of the need for additional research on the proposed subjects

ITC18: 18th international Toki conference. Development of physics and technology of stellarators/heliotrons 'en route to DEMO'. Proceedings

International Nuclear Information System (INIS)

2009-02-01

18th International Toki Conference (ITC18) was held in Toki (Japan) December 9-12 2008 organized by the National Institute for Fusion Science (NIFS). More than 150 experts in fusion research, especially in stellarator/heliotron research from Australia, Belgium, China, France, Germany, Hungary, India, Iran, Italy, Japan, Korea, Serbia, Spain, Sweden, Switzerland, and the United States of America gathered at the conference. The International Organizing Committee (IOC) chaired by O. Motojima, the International Program Committee (IPC) chaired by Y. Ogawa and the Local Organizing Committee (LOC) chaired by T. Mutoh have played the leading role in the elaboration of the scientific program of the conference. NIFS has organized the ITC as an annual meeting for fusion related sciences since its establishment in 1989. The IPC arranged 2 plenary talks, 1 review talk, 34 invited talks in addition to 109 contributed presentations including 6 oral talks. Recent developments in the experimental, theoretical and technical research show the clear route to the realization of a stellarator/heliotron type demo fusion reactor. ITC18 was devoted to review the recent developments and to discuss the next steps forward to the demo reactor realization of stellarator/heliotron type. In the conference, recent experimental results from both tokamak and stellarator/heliotron devices are reviewed and the experimental and theoretical physics of plasma confinement in toroidal devices are also discussed and confirmed that the physical base of the fusion reactor is well developed. The development of steady state operation, heating, fueling, divertors, plasma wall interaction and wall materials, advanced diagnostics for reactor relevant plasma, blanket materials as well as super conducting magnets are discussed as inevitable key physics and technologies for the DEMO reactor. Slides of all oral presentations as well as the proceedings are available at http://itc.nifs.ac.jp/. Extended papers of major

Attitudes held by Setswana L1-speaking university students toward ...

African Journals Online (AJOL)

Respondents believed that their L1 had limitations in wider society; and that it had prestige, albeit a covert one. Generally, they held favourable attitudes toward their L1. Further comprehensive research needs to be done to explore these new variables, as well as to explore their statistical significance in language attitude ...

Sexual dimorphism of the incidence of significant relationships between selected parameters of feet and characteristics of trunk in adolescents aged 14 – 18 years

Directory of Open Access Journals (Sweden)

Mirosław Mrozkowiak

2018-03-01

Full Text Available Summary Introduction. Symmetry, asymmetry, mutual relationships and concomitance have become a subject of interest of numerous researchers. The analysis of the findings obtained in the own study conducted among adolescents aged 14-18 years revealed an incidental nature and randomness of the distribution of significant correlations in each age and gender range, which made it impossible to show any regularities or dependencies between the measured parameters. Material and method. The examinations carried out in the group of teenagers aged 14 to 18 years recorded 2,343 observations, including 1,148 girls and 1,195 boys, concerning the size of 89 parameters describing trunk and feet. The station for an assessment of selected features using the photogrammetric method consisted of a computer, a card, software, a display monitor, a printer and a projection-reception device with a camera.     Findings 1. The number of feet parameters revealing significant relationships with trunk parameters which differentiated the female gender from the male one was greater; likewise, the features in women revealed a more frequent relationship. Additionally, female sex was differentiated by morphological traits, the abnormal positioning of toes and the longitudinal arch of feet. 2. The number of trunk parameters correlating with foot parameters was observed to be bigger in the female gender than in the male one. The parameters in female subjects showed more relationships and the parameters which differentiated female sex included the frontal plane and the sagittal plane to a lesser extent, whereas male gender was characterized by the sagittal plane.

Neutron-proton analyzing power data at 7. 6, 12. 0, 14. 1, 16. 0, 18. 5 MeV

Energy Technology Data Exchange (ETDEWEB)

Weisel, G.J.; Tornow, W.; Howell, C.R.; Felsher, P.D.; Alohali, M.; Chen, Z.P.; Walter, R.L. (Duke Univ., Durham, NC (US) Triangle Universities Nuclear Lab., Durham, NC (US)); Lambert, J.M.; Treado, P.A. (Georgetown Univ., Washington, DC, (US))

1990-11-15

Neutron-Proton A{sub y} ({theta}) measurements have been made at 7.6, 12.0, 14.1, 16.0, and 18.5 MeV. A sensitivity study establishes the importance of A{sub y} ({theta}) in determining the {sup 3}P{sub 0,1,2} phase shifts in n-p scattering. The data are compared to the predictions of two phase-shift studies (one of which incorporates CIB effects), and the Paris and Bonn NN potentials.

Multipolarity analysis for 14C high-energy resonance populated by (18O,16O) two-neutron transfer reaction

International Nuclear Information System (INIS)

Carbone, D.; Cavallaro, M.; Bondì, M.; Agodi, C.; Cunsolo, A.; Cappuzzello, F.; Azaiez, F.; Franchoo, S.; Khan, E.; Bonaccorso, A.; Fortunato, L.; Foti, A.; Linares, R.; Lubian, J.; Scarpaci, J. A.; Vitturi, A.

2015-01-01

The 12 C( 18 O, 16 O) 14 C reaction at 84 MeV incident energy has been explored up to high excitation energy of the residual nucleus thanks to the use of the MAGNEX spectrometer to detect the ejectiles. In the region above the two-neutron separation energy, a resonance has been observed at 16.9 MeV. A multipolarity analysis of the cross section angular distribution indicates an L = 0 character for such a transition

14. informal meeting on reactor noise

International Nuclear Information System (INIS)

1981-01-01

The present booklet contains abstracts of papers from the 14th informal meeting on reactor noise held at St. Englmar in April 1981. The main topics dealt with are vibration and loose part monitoring, leak detection, noise theory and noise applications and in the final part data processing and pattern recognition techniques. (orig.)

Report of the research results with University of Tokyo, Nuclear Engineering Research Laboratory's facilities in fiscal 1993

International Nuclear Information System (INIS)

1994-01-01

This publication summarizes the results of the joint utilization of the research 'Yayoi' and the electron beam accelerator in the Nuclear Engineering Research Laboratory, University of Tokyo, in the fiscal year 1993. In this report, the gists of 15 researches which were carried out on pile of the Yayoi, 9 researches off pile of the Yayoi and 14 researches by using the linear accelerator are collected. In addition, the 13 reports of Yayoi Study Meeting held in fiscal year 1993 are collected. Moreover, the list of the events carried out in the facility in fiscal year 1993, the registers of names of various committees, and the register of the names of persons who were in charge of joint utilization experiments in fiscal year 1993 are attached. (K.I.)

Capacity Building for Sustainable Marine Research in the Asia-Pacific Region

Science.gov (United States)

Hu, Liuming; Avril, Bernard; Zhang, Jing

2013-01-01

An international workshop on capacity building (CB) for marine research in the Asia-Pacific region (http://www.imber.info/index.php/Science/Working-Groups/Capacity-Building/2012-CB-Workshop) was held at the East China Normal University (ECNU), in Shanghai, China. The workshop brought together about 20 marine researchers and CB experts from 14 countries to discuss CB experiences, assess regional CB needs, and consider recommendations to improve regional CB, which would be of interest to other groups and other geographical regions.

Radiosynthesis of dimethyl-2-[{sup 18}F]-(fluoromethyl)-6-methyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate for L-type calcium channel imaging

Energy Technology Data Exchange (ETDEWEB)

Sadeghpour, H. [Nuclear Medicine Research Group, Agricultural, Medical and Industrial Research School (AMIRS), Karaj (Iran); Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran Univ. of Medical Sciences, Tehran (Iran); Jalilian, A.R.; Akhlaghi, M.; Mirzaei, M. [Nuclear Medicine Research Group, Agricultural, Medical and Industrial Research School (AMIRS), Karaj (Iran); Shafiee, A. [Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran Univ. of Medical Sciences, Tehran (Iran); Miri, R. [Medicinal and Natural Products Chemistry Research Center, Shiraz Univ. of Medical Sciences, Shiraz (Iran)

2008-07-01

Dimethyl 2-(fluoromethyl)-6-methyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 4a, a fluorinated nifedipine analog, has been shown to elicit significant calcium channel blocker activity using a guinea pig ileal longitudinal smooth muscle model. In order to perform biological studies for detection of L-type calcium channel distribution, we decided to prepare the [{sup 18}F]-labeled compound. The latter compound was prepared in no-carrier-added (n.c.a.) form from dimethyl 2-(bromomethyl)-6-methyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 2 in one step at 80 C in Kryptofix[222]/K[{sup 18}F]F and acetonitrile as a solvent in 15 min. Column chromatography afforded the radiochemically pure compound in 20 min. Radiochemical purity of the {sup 18}F-nifedipine was determined by RTLC and HPLC (> 98%) and specific activity of 21-48 GBq/{mu}mol (EOB). (orig.)

Photochemically activated antiviral halogenated 1,8-naphthalimides: synthesis of N,N'-bis-{2-[(5-bromo-2-[1-14C]hexyl-1H-benz[de]isoquinolin-1,3(2H)-dion-6-yl)amino]ethyl}hexanediamide

International Nuclear Information System (INIS)

Hayes, B.A.; Gupta, Surendra; Shaochieh Chang; Utecht, R.E.; Lewis, D.E.

1996-01-01

The synthesis of N,N'-bis-{2-[(5-bromo-2-[1- 14 C]hexyl-1H-benz[de]isoquinolin-1, 3(2H)-dion-6-yl)amino]ethyl}hexanediamide from 1-[1- 14 C]-hexylamine and 4-chloro-1,8-naphthalic anhydride is described. The anhydride is first converted to the 4-chloro-n-[1- 14 C]hexyl-1,8-naphthalimide by condensation with 1-[1- 14 C]-hexylamine, and the chlorine is then displaced with ethylenediamine to give the 4-(2-aminoethylamino-N-[1- 14 C]hexyl-1,8-naphthalimide. Coupling of this monomeric naphthalimide with adipoyl chloride affords the dimeric naphthalimide which is brominated regiospecifically with elemental bromine in carbon tetrachloride to afford the title compound. (author)

IsoBank workshop held at IsoEcol10 - University of Tokyo 2016

OpenAIRE

Hayden, Brian

2016-01-01

IsoBank is a repository for stable isotope values and relevant metadata. These slides were presented at a workshop held during IsoEcol10 to refine and design the IsoBank for the needs of a diverse group of researchers.

2. IAEA research co-ordination meeting on 'Atomic and molecular data for fusion plasma diagnostics'. Summary report

International Nuclear Information System (INIS)

Clark, R.E.H.

2004-05-01

This report briefly describes the proceedings, conclusions and recommendations of the 2nd Research Co-ordination Meeting (RCM) of the Co-ordinated Research Project (CRP) on 'Atomic and Molecular Data for Fusion Plasma Diagnostics' held on 16-18 June 2003 at IAEA Headquarters, Vienna. During the course of the meeting the progress achieved to data was thoroughly reviewed. It was noted that during the course of the research several new areas of data needs were revealed. During detailed discussions proposals from all participants on ongoing data needs indicated that a one year extension of the CRP would be extremely valuable with an additional RCM to be held in 2004. A specific proposal for such an extension was formulated along with the summary of the results achieved to date. (author)

30 CFR 56.12033 - Hand-held electric tools.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Hand-held electric tools. 56.12033 Section 56.12033 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL....12033 Hand-held electric tools. Hand-held electric tools shall not be operated at high potential...

Proceedings, Annual Meeting, Aquatic Plant Control Research Program (17th) Held at Sacramento, California on 16-18 November 1982.

Science.gov (United States)

1983-06-01

inhibit the germination of lettuce seeds (Baltrop and Martin 1983). Several observations are pertinent: (1) the effect is concentration dependent; (2) the...formulations of dichlobenil and fluridone were evaluated for control of hydrilla regrowth from rootstocks and from germinating tubers. Hydrilla tubers were...Carriers for Controlled Release of Fluridone -R. L. Dunn, Southern Research Institute Birmingham, Alabama 10:55 a.m. Herbicide Evaluation Program -T. K. Van

XV and XVI SERC Main Schools in Theoretical High Energy Physics held at the Saha Institute of Nuclear Physics and Harish-Chandra Research Institute

CERN Document Server

2005-01-01

Current research in High Energy Physics focuses on a number of enigmatic issues that go beyond the very successful Standard Model of particle physics. Among these are the problem of neutrino mass, the (as yet) unobserved Higgs particle, the quark-gluon plasma, quantum aspects of gravity, and the so--called hierarchy problem. Satisfactory resolution of these important questions will take much research effort in both theory and experiment. The Science & Engineering Research Council, Department of Science & Technology has sponsored a series of SERC Schools in Theoretical High Energy Physics over the past several years, to provide instruction and training to graduate students working for research degrees. This book is an outcome of the schools held at the Saha Institute of Nuclear Physics, Kolkata in 2000, and at the Harish-Chandra Research Institute, Allahabad in 2001. Based on lectures by active researchers in the field---Rajiv Gavai, Debashis Ghoshal, Dileep Jatkar, Anjan Joshipura, Biswarup Mukhopadhy...

30 CFR 57.12033 - Hand-held electric tools.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Hand-held electric tools. 57.12033 Section 57.12033 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Surface and Underground § 57.12033 Hand-held electric tools. Hand-held electric tools shall not be...

Proceedings of the 2nd specialist research meeting on the electromagnetic isotope separators and their applications

International Nuclear Information System (INIS)

Fujioka, Manabu; Kawase, Yoichi; Okano, Kotoyuki

1992-07-01

The EMIS-12 International Conference was held at Sendai in September, 1991 for the first time in Japan. It offered a nice opportunity to appeal a great progress in our country on the related fields and many interesting subjects were discussed. The second research meeting on Electromagnetic Isotope Separators and Their Applications was held at Kumatori on March 18 and 19, 1992, six months after the EMIS-12 Conference. Many interesting results obtained by using ISOLs were reported as in the previous meeting. In the present meeting, the measuring methods and the improved instruments were reported and discussed, which are fundamental for application of isotope separation methods to the interdisciplinary research fields. These valuable contributions to the meeting are involved in this Proceedings. (J.P.N.)

Application of natural isotopes ("1"8O, "2H and "1"4C) to study the dynamics of ground water in connection with river water in Bandung area

International Nuclear Information System (INIS)

Evarista Ristin Pujiindiyati and Satrio

2013-01-01

Water table in the center of Bandung basin has been decreased around 1-2 m/year since 1990 whereas in the slope has been decreased at higher level of 15 m. Water level decreasing are going to increase continuously because of increasing number of deep wells (>40 m). In 1970, there were 96 deep wells which have been registered, but now number of deep wells is estimated of more than 4700. Therefore, a study of interrelationship between groundwater and surface water, and determination of recharge area for Bandung basin are crucial research to be conducted. Stable isotopes in nature such as "2H and "1"8O, and radioactive isotope of "1"4C can give important information about groundwater dynamic pattern. In this research, 24 deep groundwater samples, 28 shallow groundwater and river water samples (Citarum, Cikapundung, Cikeruh and Citarik rivers) and shallow groundwater along the rivers were collected. Results from plotting δ"1"8O and δ"2H showed that most of shallow groundwater did not relate to river water except three locations, they are Loteng Sumbersari and Bojong Mas groundwater near to Citarum river, and groundwater near to Cikapundung river. Isotope "1"4C analysis indicated that deep groundwater of Bandung basin did not show relationship either by shallow groundwater or river water. Its iso-age line contour determined that dynamic pattern of deep groundwater in Bandung basin comes from northern and southern hills to direction of north-west area such that both areas are suggested as conservation zone. Rate of deep groundwater movement predicted from iso-age contour is around 0.25 to 3 m/year. (author)

Performance of an Electro-Hydrostatic Actuator on the F-18 Systems Research Aircraft

Science.gov (United States)

Navarro, Robert

1997-01-01

An electro-hydrostatic actuator was evaluated at NASA Dryden Flight Research Center, Edwards, California. The primary goal of testing this actuator system was the flight demonstration of power-by-wire technology on a primary flight control surface. The electro-hydrostatic actuator uses an electric motor to drive a hydraulic pump and relies on local hydraulics for force transmission. This actuator replaced the F-18 standard left aileron actuator on the F-18 Systems Research Aircraft and was evaluated throughout the Systems Research Aircraft flight envelope. As of July 24, 1997 the electro-hydrostatic actuator had accumulated 23.5 hours of flight time. This paper presents the electro-hydrostatic actuator system configuration and component description, ground and flight test plans, ground and flight test results, and lessons learned. This actuator performs as well as the standard actuator and has more load capability than required by aileron actuator specifications of McDonnell- Douglas Aircraft, St. Louis, Missouri. The electro-hydrostatic actuator system passed all of its ground tests with the exception of one power-off test during unloaded dynamic cycling.

27 CFR 46.207 - Articles held in bond.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Articles held in bond. 46... Tubes Held for Sale on April 1, 2009 Inventories § 46.207 Articles held in bond. If the dealer is a manufacturer or an export warehouse proprietor and holds articles in TTB bond on April 1, 2009, the floor...

14th March 2011 - Australian Senator the Hon. K. Carr Minister for Innovation, Industry, Science and Research in the ATLAS Visitor Centre with Collaboration Spokesperson F. Gianotti,visiting the SM18 area with G. De Rijk,the Computing centre with Department Head F. Hemmer, signing the guest book with Director-General R. Heuer with Head of International relations F. Pauss

CERN Multimedia

Jean-claude Gadmer

2011-01-01

14th March 2011 - Australian Senator the Hon. K. Carr Minister for Innovation, Industry, Science and Research in the ATLAS Visitor Centre with Collaboration Spokesperson F. Gianotti,visiting the SM18 area with G. De Rijk,the Computing centre with Department Head F. Hemmer, signing the guest book with Director-General R. Heuer with Head of International relations F. Pauss

Paleoclimatic information from deuterium and oxygen-18 in C-14 dated North Saharian groundwaters; groundwater formation in the past

International Nuclear Information System (INIS)

Sonntag, C.; Muennich, K.O.; Junghans, C.

1978-01-01

A statistical presentation of C-14 groundwater ages for various regions of the Northern Sahara reflects the alternating sequence of humid and arid periods in the late Pleistocene and Holocene. Groundwaters older than 20000 y B.P. are found all over the Sahara. Isoline-presentation of the Continental Effect in deuterium and oxygen-18 of Saharian groundwater is similar to the one in modern European groundwater. This similarity proves the Western Drift influence when in the past winter rains were sufficient for groundwater formation in the Sahara (great pluvial). The postpluvial humid phases of the Sahara during the Holocene were probably of decreasing importance from west to east. The lower deuterium excess d = delta D - 8 x delta 18 O observed in old Saharian groundwaters is interpreted to be due to a lower moisture deficit of the air over the ocean during the last ice-age. Extremely high D- and O-18 contents of modern groundwater in the Sahel zone south of the Sahara are probably due to summer rain originating from tropical rain forest evapotranspiration. (orig.) [de

A pilot analytic study of a research-level, lower-cost human papillomavirus 16, 18, and 45 test.

Science.gov (United States)

Yang, Hannah P; Walmer, David K; Merisier, Delson; Gage, Julia C; Bell, Laura; Rangwala, Sameera; Shrestha, Niwashin; Kobayashi, Lori; Eder, Paul S; Castle, Philip E

2011-09-01

The analytic performance of a low-cost, research-stage DNA test for the most carcinogenic human papillomavirus (HPV) genotypes (HPV16, HPV18, and HPV45) in aggregate was evaluated among carcinogenic HPV-positive women, which might be used to decide who needs immediate colposcopy in low-resource settings ("triage test"). We found that HPV16/18/45 test agreed well with two DNA tests, a GP5+/6+ genotyping assay (Kappa = 0.77) and a quantitative PCR assay (at a cutpoint of 5000 viral copies) (Kappa = 0.87). DNA sequencing on a subset of 16 HPV16/18/45 positive and 16 HPV16/18/45 negative verified the analytic specificity of the research test. It is concluded that the HPV16/18/45 assay is a promising triage test with a minimum detection of approximately 5000 viral copies, the clinically relevant threshold. Published by Elsevier B.V.

Proceedings of the Annual Acquisition Research Symposium (2nd), Acquisition Research: The Foundation for Innovation, Held in Monterey, California on 18-19 May 2005

Science.gov (United States)

2005-05-01

Frontiers of Entrepreneurship Research http://www.babson.edu/entrep/fer/papers95/hanks.html. Hardin, R. (1971, September). Collective action as an...sales representation and franchise laws for wrongful termination. It’s not the primary objective, but it’s a benefit. Nearly every comment...competitive sourcing, privatization initiatives, public-private partnerships, and franchising . The outcomes of such programs remain to be assessed, but

Pacific Telecommunications Council Annual Conference Proceedings (18th, Honolulu, Hawaii, January 14-18, 1996).

Science.gov (United States)

Wedemeyer, Dan J. Ed.; Nickelson, Richard, Ed.

The Pacific Telecommunications Council's 18th annual conference is presented in two volumes. The PTC'96 gathering focused on seven streams: socio-economic issues; regulatory, legal and political issues; business and finance solutions; country studies; education, training, and human resources; convergence and networks; and technologies and…

18th Asia Pacific Symposium on Intelligent and Evolutionary Systems

CERN Document Server

Ishibuchi, Hisao; Ong, Yew-Soon; Tan, Kay-Chen

2015-01-01

This book contains a collection of the papers accepted in the 18th Asia Pacific Symposium on Intelligent and Evolutionary Systems (IES 2014), which was held in Singapore from 10-12th November 2014. The papers contained in this book demonstrate notable intelligent systems with good analytical and/or empirical results.

Preparation and evaluation of ethyl [18F]fluoroacetate as a proradiotracer of [18F]fluoroacetate for the measurement of glial metabolism by PET

International Nuclear Information System (INIS)

Mori, Tetsuya; Sun, Li-Quan; Kobayashi, Masato; Kiyono, Yasushi; Okazawa, Hidehiko; Furukawa, Takako; Kawashima, Hidekazu; Welch, Michael J.; Fujibayashi, Yasuhisa

2009-01-01

Introduction: Changes in glial metabolism in brain ischemia, Alzheimer's disease, depression, schizophrenia, epilepsy and manganese neurotoxicity have been reported in recent studies. Therefore, it is very important to measure glial metabolism in vivo for the elucidation and diagnosis of these diseases. Radiolabeled acetate is a good candidate for this purpose, but acetate has little uptake in the brain due to its low lipophilicity. We have designed a new proradiotracer, ethyl [ 18 F]fluoroacetate ([ 18 F]EFA), which is [ 18 F]fluoroacetate ([ 18 F]FA) esterified with ethanol, to increase the lipophilicity of fluoroacetate (FA), allowing the measurement of glial metabolism. Methods: The synthesis of [ 18 F]EFA was achieved using ethyl O-mesyl-glycolate as precursor. The blood-brain barrier permeability of ethyl [1- 14 C]fluoroacetate ([ 14 C]EFA) was estimated by a brain uptake index (BUI) method. Hydrolysis of [ 14 C]EFA in the brain was calculated by the fraction of radioactivity in lipophilic and water fractions of homogenized brain. Using the plasma of five animal species, the stability of [ 14 C]EFA was measured. Biodistribution studies of [ 18 F]EFA in ddY mice were carried out and compared with [ 18 F]FA. Positron emission tomography (PET) scanning using common marmosets was performed for 90 min postadministration. At 60 min postinjection of [ 18 F]EFA, metabolite studies were performed. Organs were dissected from the marmosets, and extracted metabolites were analyzed with a thin-layer chromatography method. Results: The synthesis of [ 18 F]EFA was accomplished in a short time (29 min) and with a reproducible radiochemical yield of 28.6±3.6% (decay corrected) and a high radiochemical purity of more than 95%. In the brain permeability study, the BUI of [ 14 C]EFA was 3.8 times higher than that of sodium [1- 14 C]fluoroacetate. [ 14 C]EFA was hydrolyzed rapidly in rat brains. In stability studies using the plasma of five animal species, [ 14 C]EFA was stable

Spectroscopic and Collisional Data for Tungsten from 1 eV to 20 keV. Summary Report of the Final Research Coordination Meeting

International Nuclear Information System (INIS)

Chung, H.-K.; Beiersdorfer, P.; Müller, A.; Ralchenko, Yu.; Braams, B. J.

2014-12-01

The final Research Coordination Meeting of a coordinated research project (CRP) on spectroscopic and collisional data for tungsten ions in fusion plasma was held at IAEA Headquarters with 17 external experts representing 14 research groups and staff from the International Atomic Energy Agency. Participants summarized their research during the CRP and made plans for a final report. The proceedings and conclusions of the meeting are summarized here. (author)

Young people's views regarding participation in mental health and wellbeing research through social media

OpenAIRE

Monks, Helen; Cardoso, Patricia; Papageorgiou, Alana; Carolan, Catherine; Costello, Leesa; Thomas, Laura

2015-01-01

Social media is a central component in the lives of many young people, and provides innovative potential to conduct research among this population. Ethical issues around online research have been subject to much debate, yet young people have seldom been consulted to provide a youth perspective and voice. Eight (8) focus groups involving 48 Grade 9 Western Australian secondary school students aged 13-14 years were held in 2012, to investigate how young people perceive the feasibility and accep...

Journal of Medicine and Biomedical Research - Vol 14, No 1 (2015)

African Journals Online (AJOL)

Journal of Medicine and Biomedical Research - Vol 14, No 1 (2015) ... Histopathological effects of oral and subcutaneous administration of Roselle Calyx ... Ameliorative effect of Vitamin C on lead induced hepatotoxicty in rats · EMAIL ... Effect of Hibiscus sabdariffa calyx extract on stressed rabbit plasma cholesterol status ...

Lin Receives 2010 Natural Hazards Focus Group Award for Graduate Research

Science.gov (United States)

2010-11-01

Ning Lin has been awarded the Natural Hazards Focus Group Award for Graduate Research, given annually to a recent Ph.D. recipient for outstanding contributions to natural hazards research. Lin's thesis is entitled “Multi-hazard risk analysis related to hurricanes.” She is scheduled to present an invited talk in the Extreme Natural Events: Modeling, Prediction, and Mitigation session (NH20) during the 2010 AGU Fall Meeting, held 13-17 December in San Francisco, Calif. Lin will be formally presented with the award at the Natural Hazards focus group reception on 14 December 2010.

Qualitative Research in the CJA/RCV: An 18-Year Analysis (1995-2012).

Science.gov (United States)

Humble, Áine M; Green, Maureen

2016-03-01

Some researchers have suggested that qualitative research is increasing in the gerontology field, but little systematic analysis has tested this assertion. Using the Canadian Journal on Aging/La Revue canadienne du vieillissement as a case study, we analysed articles reporting on original research from 1995 to 2012. One in four articles were qualitative, and results in three-year intervals show a clear increase in qualitative research findings during this 18-year time frame: (a) 1995-1997: 10 per cent; (b) 1998-2000: 19 per cent; (c) 2001-2003: 25 per cent; (d) 2004-2006: 25 per cent; (e) 2007-2009: 29 per cent; and (f) 2010-2012: 43 per cent. In all time intervals (with the exception of 2004-2006), French language articles were more likely to use a qualitative research design compared to English language articles. Topics, methodologies, and data collection strategies are also discussed.

Report on the International Workshop “Networks, Regions and Institutions in Mongol Eurasia: A Meso-Historical Analysis”, Jerusalem, 17–18 May, 2017

OpenAIRE

Roman Hautala

2017-01-01

On May 17–18, 2017, an international workshop “Networks, Regions and Institutions in Mongol Eurasia: A Meso-Historical Analysis” was held at the Hebrew University in Jerusalem with the participation of researchers from Israel, Japan, Britain, United States, Russia, China, Hungary and Finland. The main goal of the workshop was to reveal the potential of the “meso-historical analysis” in the study of the Mongol Empire, including the simultaneous consideration of global changes in Eurasia caused...

14MeV facility and research in IPPE

Energy Technology Data Exchange (ETDEWEB)

Simakov, S P; Androsenko, A A; Androsenko, P A; Devkin, B V; Kobozev, M G; Lychagin, A A; Sinitca, V V; Talalaev, V A [Institute of Physics and Power Engineering, Obninsk (Russian Federation); Chuvilin, D Yu; Borisov, A A; Zagryadsky, V A [Institute of Atomic Energy, Moscow (Russian Federation)

1993-07-01

Review of experimental facility and research, performed at 14MeV incident neutron energy in the Institute of Physics and Power Engineering, are given. These studies cover the next topics: double differential neutron emission cross sections (DDX), neutron-gamma coincidence experiments (n, n'{gamma}) and neutron leakage spectra for spherical assemblies (benchmark). The paper contains description and main parameters of pulsed neutron generator KG-0.3, fast neutron time of flight spectrometer, measuring and data reduction procedures, review of experimental data. Results of experiments are compared with other data; evaluated data files BROND-2, ENDF/B6, JENDL-3; basic theoretical and transport model calculations. (author)

14MeV facility and research in IPPE

International Nuclear Information System (INIS)

Simakov, S.P.; Androsenko, A.A.; Androsenko, P.A.; Devkin, B.V.; Kobozev, M.G.; Lychagin, A.A.; Sinitca, V.V.; Talalaev, V.A.; Chuvilin, D.Yu.; Borisov, A.A.; Zagryadsky, V.A.

1993-07-01

Review of experimental facility and research, performed at 14MeV incident neutron energy in the Institute of Physics and Power Engineering, are given. These studies cover the next topics: double differential neutron emission cross sections (DDX), neutron-gamma coincidence experiments (n, n'γ) and neutron leakage spectra for spherical assemblies (benchmark). The paper contains description and main parameters of pulsed neutron generator KG-0.3, fast neutron time of flight spectrometer, measuring and data reduction procedures, review of experimental data. Results of experiments are compared with other data; evaluated data files BROND-2, ENDF/B6, JENDL-3; basic theoretical and transport model calculations. (author)

18th International Conference on Difference Equations and Applications

CERN Document Server

Cushing, Jim; Elaydi, Saber; Pinto, Alberto

2016-01-01

These proceedings of the 18th International Conference on Difference Equations and Applications cover a number of different aspects of difference equations and discrete dynamical systems, as well as the interplay between difference equations and dynamical systems. The conference was organized by the Department of Mathematics at the Universitat Autònoma de Barcelona (UAB) under the auspices of the International Society of Difference Equations (ISDE) and held in Barcelona (Catalonia, Spain) in July 2012. Its purpose was to bring together experts and novices in these fields to discuss the latest developments. The book gathers contributions in the field of combinatorial and topological dynamics, complex dynamics, applications of difference equations to biology, chaotic linear dynamics, economic dynamics and control and asymptotic behavior, and periodicity of difference equations. As such it is of interest to researchers and scientists engaged in the theory and applications of difference equations and discrete dy...

FAA/NASA Joint University Program for Air Transportation Research, 1992-1993

Science.gov (United States)

Morrell, Frederick R. (Compiler)

1994-01-01

The research conducted during the academic year 1992-1993 under the FAA/NASA sponsored Joint University Program for Air Transportation Research is summarized. The year end review was held at Ohio University, Athens, Ohio, 17-18 June 1993. The Joint University Program is a coordinated set of three grants sponsored by the Federal Aviation Administration and NASA Langley Research Center, one each with the Massachusetts Institute of Technology, Ohio University, and Princeton University. Completed works, status reports, and annotated bibliographies are presented for research topics, which include navigation, guidance, and control theory and practice, aircraft performance, human factors and air traffic management. An overview of the year's activities for each university is also presented.

Marine Bioinorganic Chemistry Workshop Held in Heron Island on 28 June - 2nd July 1989

Science.gov (United States)

1990-02-09

Vilter, H. Phytochemistry, 1984, 23, 1387-1390. 2. Vilter, H. Botanica Marina, 1983, 26, 451-455. 3. Wever, R., Plat, H. and De Boer, E., Biochim. Biophys...and DSc (1977) Vf degrees from the University of Melbourne, where he held teaching and research positions. His major research interests involve the

Research progress in radiolabeling imaging mechanism and clinical applications of "1"8F-FDG

International Nuclear Information System (INIS)

Zhai Shizhen; Yang Zhi; Du Jin

2011-01-01

PET/CT is one of the most advanced technologies contemporarily, achieving the combination of anatomical imaging and functional imaging. "1"8F-FDG is the most important positron radiopharmaceutical, which was used over 95% in total PET/CT imaging. FDG- PET has been extensively used in diagnosis of several kinds of diseases such as tumor, cardiac disease and epilepsy. The present review provides the history, the quality control, the imaging mechanisms as well as the research progress of the clinical applications of "1"8F-FDG. (authors)

Conceptions of Healthy Aging Held by Relatives of Older Persons in Isan-Thai Culture: A Phenomenographic Study.

Science.gov (United States)

Manasatchakun, Pornpun; Roxberg, Åsa; Asp, Margareta

2018-01-01

In Thailand, family nurses are expected to provide support for older persons and their family members to promote healthy aging. Family bonds are strong, and relatives are expected to take care of their older family members. However, there is limited research on how older persons' family members perceive healthy aging. This study aimed to describe the conceptions of healthy aging held by the children and grandchildren of older persons in northeast Thailand. In a phenomenographic study, 14 interviews were performed to qualitatively analyze different conceptions of healthy aging. Four descriptive categories emerged: being independent, not being afflicted by diseases or illnesses, being a giver and a receiver, and being wise. The conceptions of healthy aging entail both autonomy and interdependence. The relative's perspective needs to be considered when policies relating to healthy aging are implemented in the community and when family nurses provide support to families to promote healthy aging.

14C Records from Indonesian Sea

International Nuclear Information System (INIS)

Baresic, J.; Fallon, S.; Mazerat, J.

2013-01-01

To investigate ocean currents and past climate events affecting the Indonesian throughflow (ITF), a radiocarbon record from a Porites coral collected from Alor Island, Indonesia, was constructed. Porites corals are often used in paleoclimate research and water mass circulation studies in the Tropics because of their abundance in the region and growth rate of 8 - 20 mm/y. These characteristics allow reconstructions of past environmental changes on weekly to annual time scales. At this point radiocarbon coral results from Alor cover approximately 30 years. An age model was constructed using the sea surface temperature proxy δ18O. Alor radiocarbon results were compared with previous measurements obtained from Padang and Langkai corals. a14C values obtained from the Alor coral display a strong seasonal cycle, high values during Australian summer and low values during Australian winter. Higher a 14C summer values indicate inflow of waters enriched by 14C through Makassar Strait from the North Pacific Ocean and Java Sea surface water. Summer a14C values are also enhanced by summer stratification. Winter values indicate upwelling of deep Ocean waters within the research area and transport of 14C-depleted waters from the Banda Sea, which has input from the South Pacific Ocean (lower a14C than North Pacific). Therefore, the a14C coral record reflects the movement of enriched water from North Pacific to Indian Ocean through Makassar Strait during summer and upwelling of depleted surface waters from the Banda Sea during the winter. Lower a14C dips could be attributed to strong El Nino events, which would enhance surface water mixing and upwelling of low radiocarbon deep waters. Water transport from North Pacific Ocean decreases during El Nino events also contributing to lowering of a14C signal.(author)

AFOSR Contractors Meeting in Propulsion Held in Atlantic City, New Jersey on 14 - 18 June 1993

Science.gov (United States)

1994-04-20

It has been first hypothesized by Alfvdn in 1942 and then invoked in the context of cometary physics, the formation of the solar system, planetary tori...317)494-2713 I Dr Moshe Lavid Dr C K Law ML Energia , Inc. Department of Mechanical andjP. 0. Box 1468 Aerospace Engineering Princeton NJ 08540

Atmospheric histories and growth trends of C4F10, C5F12, C6F14, C7F16 and C8F18

Directory of Open Access Journals (Sweden)

R. F. Weiss

2012-05-01

Full Text Available Atmospheric observations and trends are presented for the high molecular weight perfluorocarbons (PFCs: decafluorobutane (C4F10, dodecafluoropentane (C5F12, tetradecafluorohexane (C6F14, hexadecafluoroheptane (C7F16 and octadecafluorooctane (C8F18. Their atmospheric histories are based on measurements of 36 Northern Hemisphere and 46 Southern Hemisphere archived air samples collected between 1973 to 2011 using the Advanced Global Atmospheric Gases Experiment (AGAGE "Medusa" preconcentration gas chromatography-mass spectrometry systems. A new calibration scale was prepared for each PFC, with estimated accuracies of 6.8% for C4F10, 7.8% for C5F12, 4.0% for C6F14, 6.6% for C7F16 and 7.9% for C8F18. Based on our observations the 2011 globally averaged dry air mole fractions of these heavy PFCs are: 0.17 parts-per-trillion (ppt, i.e., parts per 1012 for C4F10, 0.12 ppt for C5F12, 0.27 ppt for C6F14, 0.12 ppt for C7F16 and 0.09 ppt for C8F18. These atmospheric mole fractions combine to contribute to a global average radiative forcing of 0.35 mW m−2, which is 6% of the total anthropogenic PFC radiative forcing (Montzka and Reimann, 2011; Oram et al., 2012. The growth rates of the heavy perfluorocarbons were largest in the late 1990s peaking at 6.2 parts per quadrillion (ppq, i.e., parts per 1015 per year (yr for C4F10, at 5.0 ppq yr−1 for C5F12 and 16.6 ppq yr−1 for C6F14 and in the early 1990s for C7F16 at 4.7 ppq yr−1 and in the mid 1990s for C8F18 at 4.8 ppq yr−1. The 2011 globally averaged mean atmospheric growth rates of these PFCs are subsequently lower at 2.2 ppq yr−1 for C4F10, 1.4 ppq yr−1 for C5F12, 5.0 ppq yr−1 for C6F14, 3.4 ppq yr−1 for C7F16 and 0.9 ppq yr−1 for C8F18. The more recent slowdown in the growth rates suggests that emissions are declining as compared to the 1980s and 1990s.

Predictor Relationships between Values Held by Married Individuals, Resilience and Conflict Resolution Styles: A Model Suggestion

Science.gov (United States)

Tosun, Fatma; Dilmac, Bulent

2015-01-01

The aim of the present research is to reveal the predictor relationships between the values held by married individuals, resilience and conflict resolution styles. The research adopts a relational screening model that is a sub-type of the general screening model. The sample of the research consists of 375 married individuals, of which 173 are…

People and things. CERN Courier, Jun 1987, v. 27(5)

Energy Technology Data Exchange (ETDEWEB)

Anon.

1987-06-15

The article reports on achievements of various people, staff changes and position opportunities within the CERN organization and contains news updates on upcoming or past events:; An International Conference on the Physics and Astrophysics of Quark-Gluon Plasma will be held from 8-12 February 1988 at the Tata Institute for Fundamental Research, Bombay, India. This year the Joliot-Curie School of Nuclear Physics, arranged jointly by the French National Institute of Nuclear and Particle Physics (IN2P3) and the Institute for Fundamental Research of the French Atomic Energy Commission, will be held at Maubuisson, Gironde (France) from 14-18 September. The Europhysics Conference on Control Systems for Experimental Physics, sponsored by the European Physics Society (EPS) and CERN, and organized by the EPS Inter divisional Group on Experimental Physics Control Systems, will be held in Villars-sur-Ollon, Switzerland, from 28 September to 2 October.

People and things. CERN Courier, Jun 1987, v. 27(5)

International Nuclear Information System (INIS)

Anon.

1987-01-01

The article reports on achievements of various people, staff changes and position opportunities within the CERN organization and contains news updates on upcoming or past events:; An International Conference on the Physics and Astrophysics of Quark-Gluon Plasma will be held from 8-12 February 1988 at the Tata Institute for Fundamental Research, Bombay, India. This year the Joliot-Curie School of Nuclear Physics, arranged jointly by the French National Institute of Nuclear and Particle Physics (IN2P3) and the Institute for Fundamental Research of the French Atomic Energy Commission, will be held at Maubuisson, Gironde (France) from 14-18 September. The Europhysics Conference on Control Systems for Experimental Physics, sponsored by the European Physics Society (EPS) and CERN, and organized by the EPS Inter divisional Group on Experimental Physics Control Systems, will be held in Villars-sur-Ollon, Switzerland, from 28 September to 2 October

Research project at Nagoya University

International Nuclear Information System (INIS)

Furukawa, M.; Nakai, N.; Nakano, E.

1981-01-01

We will have a dedicated facility from General Ionex Corporation at the Radioisotope Center of Nagoya Univeriy in 1981 FY. The building to install the machine was already completed in March 1981. We have held meetings of potential users of the facility and various research proposals have been presented by the participants from many departments of the university. The present research project at Nagoya is mainly devoted to the development of radiocarbon dating by the accelerator mass spectrometry, in which most of the users are interested. There are many archeological and geological samples in Japan which have too little carbon compounds for analysis by conventional radioactivity measurements. Concentrations of 14 C in these samples can be determined by the new technique. Some of the proposals connected with radiocarbon measurements are discussed

18 CFR 35.14 - Fuel cost and purchased economic power adjustment clauses.

Science.gov (United States)

2010-04-01

... economic power adjustment clauses. 35.14 Section 35.14 Conservation of Power and Water Resources FEDERAL... SCHEDULES AND TARIFFS Other Filing Requirements § 35.14 Fuel cost and purchased economic power adjustment clauses. (a) Fuel adjustment clauses (fuel clause) which are not in conformity with the principles set out...

FOREWORD: 18th International School on Condensed Matter Physics

Science.gov (United States)

Dimova-Malinovska, Doriana; Genova, Julia; Nesheva, Diana; Petrov, Alexander G.; Primatarowa, Marina T.

2014-12-01

We are delighted to present the Proceedings of the 18th International School on Condensed Matter Physics: Challenges of Nanoscale Science: Theory, Materials, Applications, organized by the Institute of Solid State Physics of the Bulgarian Academy of Sciences and chaired by Professor Alexander G Petrov. On this occasion the School was held in memory of Professor Nikolay Kirov (1943-2013), former Director of the Institute and Chairman between 1991 and 1998. The 18ISCMP was one of several events dedicated to the 145th anniversary of the Bulgarian Academy of Sciences in 2014, and was held in the welcoming Black Sea resort of St. Constantine and Helena near Varna, at the Hotel and Congress Centre Frederic Joliot-Curie. Participants from 16 countries delivered 32 invited lectures, and 71 contributed posters were presented over three lively and well-attended evening sessions. Manuscripts submitted to the Proceedings were refereed in accordance with the guidelines of the Journal of Physics: Conference Series, and we believe the papers published herein testify to the high technical quality and diversity of contributions. A satellite meeting, Transition Metal Oxide Thin Films - Functional Layers in Smart Windows and Water Splitting Devices: Technology and Optoelectronic Properties was held in parallel with the School (http://www.inera.org, 3-6 Sept 2014). This activity, which took place under the FP7-funded project INERA, offered opportunities for crossdisciplinary discussions and exchange of ideas between both sets of participants. As always, a major factor in the success of the 18ISCMP was the social programme, headed by the organized events (Welcome and Farewell Parties) and enhanced in no small measure by a variety of pleasant local restaurants, bars and beaches. We are most grateful to staff of the Journal of Physics: Conference Series for their continued support for the School, this being the third occasion on which the Proceedings have been published under its

Proceedings of the flat-plate solar array project research forum on photovoltaic metallization systems

Energy Technology Data Exchange (ETDEWEB)

None

1983-11-15

A Photovoltaic Metallization Research Forum, under the sponsorship of the Jet Propulsion Laboratory's Flat-Plate Solar Array Project and the US Department of Energy, was held March 16-18, 1983 at Pine Mountain, Georgia. The Forum consisted of five sessions, covering (1) the current status of metallization systems, (2) system design, (3) thick-film metallization, (4) advanced techniques and (5) future metallization challenges. Twenty-three papers were presented.

Cytokeratin 8/18 expression indicates a poor prognosis in squamous cell carcinomas of the oral cavity

International Nuclear Information System (INIS)

Fillies, Thomas; Werkmeister, Richard; Packeisen, Jens; Brandt, Burkhard; Morin, Philippe; Weingart, Dieter; Joos, Ulrich; Buerger, Horst

2006-01-01

Intermediary filaments are involved in cell motility and cancer progression. In a variety of organs, the expression of distinct intermediary filaments are associated with patient prognosis. In this study, we seeked to define the prognostic potential of cytokeratin and vimentin expression patterns in squamous cell carcinomas (SCC's) of the oral cavity. 308 patients with histologically proven and surgically treated squamous cell carcinomas of the oral cavity were investigated for the immunohistochemical expression of a variety of intermediary filaments including high- and low-molecular weight cytokeratins (Ck's), such as Ck 5/6, Ck 8/18, Ck 1, CK 10, Ck 14, Ck 19 and vimentin, using the tissue microarray technique. Correlations between clinical features and the expression of Cytokeratins and vimentin were evaluated statistically by Kaplan-Meier curves and multivariate Cox regression analysis. The expression of Ck 8/18 and Ck 19 were overall significantly correlated with a poor clinical prognosis (Ck 8/18 p = 0.04; Ck19 p < 0.01). These findings could also be reproduced for Ck 8/18 in primary nodal-negative SCC's and held true in multivariate-analysis. No significant correlation with patient prognosis could be found for the expression of the other cytokeratins and for vimentin. The expression of Ck 8/18 in SCC's of the oral cavity is an independent prognostic marker and indicates a decreased overall and progression free survival. These results provide an extended knowledge about the role of intermediary filament expression patterns in SCC's

The second workshop of neutron science research program

Energy Technology Data Exchange (ETDEWEB)

Yasuda, Hideshi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Tone, Tatsuzo [eds.

1997-11-01

The Japan Atomic Energy Research Institute(JAERI) has been proposing the Neutron Science Research Program to explore a broad range of basic research and the nuclear technology including actinide transmutation with use of powerful spallation neutron sources. For this purpose, the JAERI is conducting the research and development of an intense proton linac, the development of targets, as well as the conceptual design study of experimental facilities required for applications of spallation neutrons and secondary particle beams. The Special Task Force for Neutron Science Initiative was established in May 1996 to promote aggressively and systematically the Neutron Science Research Program. The second workshop on neutron science research program was held at the JAERI Tokai Research Establishment on 13 and 14 March 1997 for the purpose of discussing the results obtained since the first workshop in March 1996. The 27 of the presented papers are indexed individually. (J.P.N.)

Space Weather Research Presented at the 2007 AGU Fall Meeting

Science.gov (United States)

Kumar, Mohi

2007-12-01

AGU's 47th annual Fall Meeting, held 10-14 December 2007 in San Francisco, Calif., was the largest gathering of geoscientists in the Union's history. More than 14,600 people attended. The Space Physics and Aeronomy (SPA) sections sported excellent turnout, with more than 1300 abstracts submitted over 114 poster and oral sessions. Topics discussed that related to space weather were manifold: the nature of the Sun-Earth system revealed through newly launched satellites, observations and models of ionospheric convection, advances in the understanding of radiation belt physics, Sun-Earth coupling via energetic coupling, data management and archiving into virtual observatories, and the applications of all this research to space weather forecasting and prediction.

Summary report of second IAEA research coordination meeting on tritium inventory in fusion reactors

International Nuclear Information System (INIS)

Clark, R.E.H.

2006-03-01

Detailed discussions were held during an RCM at IAEA Headquarters on 18-19 October 2004 to review the progress made in the CRP on 'Tritium Inventory in Fusion Reactors'. Participants summarized the specific results obtained during the initial phase of the Coordinated Research Project (CRP), and considered the impact of the data generated on the design of fusion devices. Areas with further research needs were identified, and a set of outstanding objectives was formulated for the continuation of the CRP. The discussions, conclusions and recommendations of the RCM are briefly described in this report. (author)

Session summaries for workshop meeting on virtual reality applications in process industry maintenance training, outage planning, control room retrofits and design, 17th - 18th September 1998

International Nuclear Information System (INIS)

Louka, Michael N.

1998-09-01

A well-attended workshop was held in Halden 17th - 18th September 1998 to discuss VR applications in the process industry. In particular, maintenance training, outage planning, decommissioning, control room retrofits, and design were discussed. It is clear that there is a great deal of interest in both current and potential use of VR technology. The workshop participants represented a diverse range of research disciplines, as well as utilities, vendors and regulators (author) (ml)

Preparation and evaluation of ethyl [{sup 18}F]fluoroacetate as a proradiotracer of [{sup 18}F]fluoroacetate for the measurement of glial metabolism by PET

Energy Technology Data Exchange (ETDEWEB)

Mori, Tetsuya [Biomedical Imaging Research Center, University of Fukui, Fukui 910-1193 (Japan); Sun, Li-Quan [Biomedical Imaging Research Center, University of Fukui, Fukui 910-1193 (Japan); School of Life Science and Technology, Beijing Institute of Technology, Beijing 100081 (China); Kobayashi, Masato [Biomedical Imaging Research Center, University of Fukui, Fukui 910-1193 (Japan); Kiyono, Yasushi [Biomedical Imaging Research Center, University of Fukui, Fukui 910-1193 (Japan)], E-mail: ykiyono@u-fukui.ac.jp; Okazawa, Hidehiko; Furukawa, Takako [Biomedical Imaging Research Center, University of Fukui, Fukui 910-1193 (Japan); Kawashima, Hidekazu [Graduate School of Medicine, Kyoto University, Kyoto 606-8501 (Japan); Welch, Michael J. [Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110 (United States); Fujibayashi, Yasuhisa [Biomedical Imaging Research Center, University of Fukui, Fukui 910-1193 (Japan)

2009-02-15

Introduction: Changes in glial metabolism in brain ischemia, Alzheimer's disease, depression, schizophrenia, epilepsy and manganese neurotoxicity have been reported in recent studies. Therefore, it is very important to measure glial metabolism in vivo for the elucidation and diagnosis of these diseases. Radiolabeled acetate is a good candidate for this purpose, but acetate has little uptake in the brain due to its low lipophilicity. We have designed a new proradiotracer, ethyl [{sup 18}F]fluoroacetate ([{sup 18}F]EFA), which is [{sup 18}F]fluoroacetate ([{sup 18}F]FA) esterified with ethanol, to increase the lipophilicity of fluoroacetate (FA), allowing the measurement of glial metabolism. Methods: The synthesis of [{sup 18}F]EFA was achieved using ethyl O-mesyl-glycolate as precursor. The blood-brain barrier permeability of ethyl [1-{sup 14}C]fluoroacetate ([{sup 14}C]EFA) was estimated by a brain uptake index (BUI) method. Hydrolysis of [{sup 14}C]EFA in the brain was calculated by the fraction of radioactivity in lipophilic and water fractions of homogenized brain. Using the plasma of five animal species, the stability of [{sup 14}C]EFA was measured. Biodistribution studies of [{sup 18}F]EFA in ddY mice were carried out and compared with [{sup 18}F]FA. Positron emission tomography (PET) scanning using common marmosets was performed for 90 min postadministration. At 60 min postinjection of [{sup 18}F]EFA, metabolite studies were performed. Organs were dissected from the marmosets, and extracted metabolites were analyzed with a thin-layer chromatography method. Results: The synthesis of [{sup 18}F]EFA was accomplished in a short time (29 min) and with a reproducible radiochemical yield of 28.6{+-}3.6% (decay corrected) and a high radiochemical purity of more than 95%. In the brain permeability study, the BUI of [{sup 14}C]EFA was 3.8 times higher than that of sodium [1-{sup 14}C]fluoroacetate. [{sup 14}C]EFA was hydrolyzed rapidly in rat brains. In stability

Sustainable production of wood and non-wood forest products: Proceedings of IUFRO Division 5 Research Groups 5.11 and 5.12, Rotorua, New Zealand, March 11–15, 2003.

Science.gov (United States)

E.M. Donoghue; G.L. Benson; J.L. Chamberlain

2004-01-01

This proceedings is a collection of 18 papers and extended abstracts based on talks presented at the International Union of Forest Research Organizations (IUFRO) All Division 5 Conference, held in Rotorua, New Zealand, March 11–15, 2003. This conference emphasized the many ways that forest products research can contribute to sustainable choices in forest management....

Supercomputers and parallel computation. Based on the proceedings of a workshop on progress in the use of vector and array processors organised by the Institute of Mathematics and its Applications and held in Bristol, 2-3 September 1982

International Nuclear Information System (INIS)

Paddon, D.J.

1984-01-01

This book is based on the proceedings of a conference on parallel computing held in 1982. There are 18 papers which cover the following topics: VLSI parallel architectures, the theory of parallel computing and vector and array processor computing. One paper on 'Tough Problems in Reactor Design' is indexed separately. All the contributions are on research done in the United Kingdom. Although much of the experience in array processor computing is associated with the ICL distributed array processor (DAP) and this is reflected in the contributions, the research relating to the ICL DAP is relevant to all types of array processors. (UK)

Antitank Warfare Seminar Held in Washington, DC on 14-15 October 1976.

Science.gov (United States)

1976-10-01

the pants feeling and he could see the slant range to the tank, he would roll out just for a second, stabilize I- his platform and fire and then...steady platform . Then he would immediately make this large turn and he would roll in for attack. (Unintelligible) Your question of whether it was more...wic.A k14flnf .. .uenn wix 10 ode4t 20 km, hintev de’t F’runt wa’~en... .10, 20 mat am Tag, &enn Itch abet achon ei.ne hatbe Stunde An 1~tug hatte

Proceedings of the Regional Seminar on Earthquake Engineering (13th) Held in Istanbul, Turkey on 14-24 September 1987.

Science.gov (United States)

1987-09-01

Earthquake Engineering Conference held in San Francisco in July 198 . It is an international collaboration programme disigned to mitigate the damage...i0 25 30 days Fig. Field data showing restoring Processes of life line os ystems. :j50 0i i i . . rH l o? 50- f- Kitchen fire sources J-0 Kerosene...and another, intermediate, narrow, lobby, serving as entrance, kitchen , a.s.o. As a matter of fact, statistics indicate that the ra- tio of 3 room

Conceptions of Healthy Aging Held by Relatives of Older Persons in Isan-Thai Culture: A Phenomenographic Study

Directory of Open Access Journals (Sweden)

Pornpun Manasatchakun

2018-01-01

Full Text Available In Thailand, family nurses are expected to provide support for older persons and their family members to promote healthy aging. Family bonds are strong, and relatives are expected to take care of their older family members. However, there is limited research on how older persons’ family members perceive healthy aging. This study aimed to describe the conceptions of healthy aging held by the children and grandchildren of older persons in northeast Thailand. In a phenomenographic study, 14 interviews were performed to qualitatively analyze different conceptions of healthy aging. Four descriptive categories emerged: being independent, not being afflicted by diseases or illnesses, being a giver and a receiver, and being wise. The conceptions of healthy aging entail both autonomy and interdependence. The relative’s perspective needs to be considered when policies relating to healthy aging are implemented in the community and when family nurses provide support to families to promote healthy aging.

Growth and survival of Escherichia coli O157:H7 and Listeria monocytogenes in egg products held at different temperatures.

Science.gov (United States)

Yang, S E; Chou, C C

2000-07-01

Growth and survival of Escherichia coli O157:H7 and Listeria monocytogenes in steamed eggs and scrambled eggs held at different temperatures (5, 18, 22, 37, 55, and 60 degrees C) were investigated in the present study. Among the holding temperatures tested, both pathogens multiplied best at 37 degrees C followed by 22, 18, and 5 degrees C. In general, E. coli O157:H7 grew better in the egg products than L. monocytogenes did at all the storage temperatures tested except at 5 degrees C. E. coli O157:H7 did not grow in steamed eggs and scrambled eggs held at 5 degrees C. L. monocytogenes showed a slight population increase of approximately 0.6 to 0.9 log CFU/g in these egg products at the end of the 36-h storage period at 5 degrees C. The population of both pathogens detected in the egg products was affected by the initial population, holding temperature, and length of the holding period. It was also noted that L. monocytogenes was more susceptible than E. coli O157:H7 in steamed eggs held at 60 degrees C. After holding at 60 degrees C for 1 h, no detectable viable cells of L. monocytogenes with a population reduction of 5.4 log CFU/g was observed in steamed eggs, whereas a lower population reduction of only approximately 0.5 log CFU/ml was noted for E. coli O157:H7.

Proceedings of the fifth seminar on software development in nuclear energy research

International Nuclear Information System (INIS)

Hasegawa, Akira; Maekawa, Hiroshi; Fujiki, Kazuo; Harada, Hiroo

1989-02-01

These proceedings are the compilations of papers presented to the Fifth Seminar on Software Development in Nuclear Energy Research held at Tokai Research Establishment, Japan Atomic Energy Research Institute (JAERI), October 17 - 18, 1988. The seminar was organized in cooperation with Japanese Committee on Reactor Physics (JCRP) and Japanese Nuclear Code Committee (JNCC). The topics of seminar include the invited papers on the subjects: - Net work for Atomic Energy Research - (1) Present and future of Networks, (2) Applications of Networks, (3) Panel Discussion : Usage of Networks in Atomic Energy Research, - Frontier of Simulation Softwares for the Environment Safety - (4) Numerical Simulation of Grobal Scale Dispersion on the Chernobyl Accident, and (5) Oceanic Diffusion and Safety Evaluation of High Level Waste Disposal in Geological Media. (author)

Learning to (Re)member the Things We've Learned to Forget: Endarkened Feminisms, Spirituality, and the Sacred Nature of Research and Teaching. Black Studies and Critical Thinking. Volume 18

Science.gov (United States)

Dillard, Cynthia B.

2012-01-01

Feminist research has both held and contested experience as a category of epistemological importance, often as a secular notion. However, spirituality and sacred knowing are also fundamental to a Black/endarkened feminist epistemology in teaching and research, given the historical and cultural experiences of African ascendant women worldwide. How…

14th South African Psychology Congress | Laher | African Safety ...

African Journals Online (AJOL)

In response to the xenophobic violence that erupted in South Africa in May 2008, 'Respecting diversity' was an aptly chosen theme for the 14th South African Psychology Congress, held at Emperors Palace in Johannesburg, South Africa from 26 to 29 August 2008. The congress was hosted by the Psychological Society of ...

Interaction of the cesium cation with calix[4]arene-bis(t-octylbenzo-18-crown-6): extraction and DFT study

Czech Academy of Sciences Publication Activity Database

Makrlík, E.; Toman, Petr; Vaňura, P.; Moyer, B. A.

2013-01-01

Roč. 1033, 6 February (2013), s. 14-18 ISSN 0022-2860 R&D Projects: GA ČR(CZ) GAP205/10/2280 Institutional research plan: CEZ:AV0Z40500505 Institutional support: RVO:61389013 Keywords : cesium cation * calix[4]arene-bis(t-octylbenzo-18-crown-6) * complexation Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.599, year: 2013

Analysis of Information Remaining on Hand Held Devices Offered for Sale on the Second Hand Market

Directory of Open Access Journals (Sweden)

Andy Jones

2008-06-01

Full Text Available The ownership and use of mobile phones, Personal Digital Assistants and other hand held devices is now ubiquitous both for home and business use. The majority of these devices have a high initial cost, a relatively short period before they become obsolescent and a relatively low second hand value.  As a result of this, when the devices are replaced, there are indications that they tend to be discarded.  As technology has continued to develop, it has led to an increasing diversity in the number and type of devices that are available, and the processing power and the storage capacity of the digital storage in the device. All organisations, whether in the public or private sector increasingly use hand held devices that contain digital media for the storage of information relating to their business, their employees or their customers. Similarly, individual private users increasingly use hand held devices containing digital media for the storage of information relating to their private lives.The research revealed that a significant number of organisations and private users are ignorant or misinformed about the volume and type of information that is stored on the hand held devices and the media on which it is stored.  It is apparent that they have either not considered, or are unaware of, the potential impact of this information becoming available to their competitors or those with criminal intent.This main purpose of this study was to gain an understanding of the volume and type of information that may remain on hand held devices that are offered for sale on the second hand market.  A second aim of the research was to determine the level of damage that could, potentially be caused, if the information that remains on the devices fell into the wrong hands.  The study examined a number of hand held devices that had been obtained from sources in the UK and Australia that ranged from internet auction sites, to private sales and commercial

Natural Language Processing Systems Evaluation Workshop Held in Berkely, California on 18 June 1991

Science.gov (United States)

1991-12-01

re~arded as -a fairly complete dictionary contains about 18,000 itemsw at soluition to the domain-restricted task at tzanlating present, and will be... dictionary access and so on, with an article. Unfortunately, the Weidner system did but as time goes on, one might imagine functionality not know that...superfast type. looped tht it A31l be built with taste by peo. writer ought to be possible in the monolingual case pie who understand languages and

29 CFR 2520.103-11 - Assets held for investment purposes.

Science.gov (United States)

2010-07-01

... Securities Exchange Act of 1934 or quoted on NASDAQ; (3) Assets held for investment purposes shall not... assets held for investment purposes the 1,000 shares of stock S under paragraph (b)(1) of this section... 29 Labor 9 2010-07-01 2010-07-01 false Assets held for investment purposes. 2520.103-11 Section...

Looking back, looking forward: A historical reflection on psychotherapy process research.

Science.gov (United States)

Knobloch-Fedders, Lynne M; Elkin, Irene; Kiesler, Donald J

2015-01-01

In 1983, a group of 14 prominent psychotherapy process researchers attended a workshop sponsored by the US National Institute of Mental Health. Although the previous decade had seen a marked emphasis on psychotherapy outcome research, there had also been several major advances in the field of process research. The goals of the workshop were to review the current state of the field, address methodological and conceptual issues, and provide recommendations to advance scholarship in this area. In this paper, we summarize the major themes of the workshop and consider the degree to which its recommendations have come to fruition via subsequent developments in the field. Although 30 years have passed since the workshop was held, its insights remain highly relevant to psychotherapy process research today.

THE RGB AND AGB STAR NUCLEOSYNTHESIS IN LIGHT OF THE RECENT {sup 17}O(p, {alpha}){sup 14}N AND {sup 18}O(p, {alpha}){sup 15}N REACTION-RATE DETERMINATIONS

Energy Technology Data Exchange (ETDEWEB)

Palmerini, S.; Sergi, M. L.; La Cognata, M.; Pizzone, R. G.; Spitaleri, C. [INFN-Laboratori Nazionali del Sud, Catania (Italy); Lamia, L. [Dipartimento di Fisica e Astronomia, Universita di Catania, Catania (Italy)

2013-02-20

In recent years, the Trojan Horse Method (THM) has been used to investigate the low-energy cross sections of proton-induced reactions on A = 17 and A = 18 oxygen isotopes, overcoming extrapolation procedures and enhancement effects due to electron screening. In particular, the strengths of the 20 keV and 65 keV resonances in the {sup 18}O(p, {alpha}){sup 15}N and {sup 17}O(p, {alpha}){sup 14}N reactions, respectively, have been extracted, as well as the contribution of the tail of the broad 656 keV resonance in the {sup 18}O(p, {alpha}){sup 15}N reaction inside the Gamow window. The strength of the 65 keV resonance in the {sup 17}O(p, {alpha}){sup 14}N reaction, measured by means of the THM, has been used to renormalize the corresponding resonance strength in the {sup 17}O + p radiative capture channel. As a result, more accurate reaction rates for the {sup 18}O(p, {alpha}){sup 15}N, {sup 17}O(p, {alpha}){sup 14}N, and {sup 17}O(p, {gamma}){sup 18}F processes have been deduced, devoid of systematic errors due to extrapolation or the electron screening effect. Such rates have been introduced into state-of-the-art red giant branch and asymptotic giant branch (AGB) models for proton-capture nucleosynthesis coupled with extra-mixing episodes. The predicted abundances have been compared with isotopic compositions provided by geochemical analysis of presolar grains. As a result, an improved agreement is found between the models and the isotopic mix of oxide grains of AGB origins, whose composition is the signature of low-temperature proton-capture nucleosynthesis. The low {sup 14}N/{sup 15}N found in SiC grains cannot be explained by the revised nuclear reaction rates and remains a serious problem that has not been satisfactorily addressed.

12 CFR 745.5 - Accounts held by executors or administrators.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Accounts held by executors or administrators... § 745.5 Accounts held by executors or administrators. Funds of a decedent held in the name of the decedent or in the name of the executor or administrator of the decedent's estate and deposited in one or...

Use of isotopic tracers in pesticide and environmental contamination research

International Nuclear Information System (INIS)

Casida, J.E.

1976-01-01

The era of synthetic organic pesticides, starting with DDT and the herbicide 2,4-D about 1940, coincides with that of rapid advances in radiotracer applications. This is indeed fortunate since isotopic experiments are an essential step in evaluating each new pesticide and in continually reassessing older compounds for safety and most efficient utilization. This research is carried out in all developed nations with important supplementation on local problems or use conditions from investigations in the developing countries. Several slides will help illustrate the sequence of studies for establishing the disposition and fate of pesticides and other environmental contaminants.It is clear that very little of the pesticide ever contacts the pest. Pesticide chemicals are generally applied at dosages of 0.2 to 2 kilogram per hectare from one to five or more times per crop season. Less than 0.01% of an insecticide is absorbed or ingested by the pest insect. The remaining amount, more than 99.99%, is an environmental contaminant, a portion of which is a potential residue in food, feed and fibre. Isotopic research is critical in understanding or solving several aspects of the problem. The isotopic label is introduced into the chemical by synthesis in a commercial or university laboratory or in a national or regional atomic research centre. The most common radioisotopes used are tritium, 14carbon, 32phosphorus, 35sulphur and 36chlorine. Stable isotopes are becoming increasingly important in pesticide research, particularly carbon 13, nitrogen 15 and oxygen 18. The initial studies usually involve administration of the 14 carbon-labelled pesticide to rats, which are then held in metabolism cages that allow separate collection of expired gases, urine and faeces. The products in the excreta are identified by various chromatographic and spectroscopic techniques. The persistence of the chemical and its metabolites in various tissues is also determined to make sure that the material

2012 Photosynthesis Gordon Research Conference and Seminar, JUL 7-13, 2012

Energy Technology Data Exchange (ETDEWEB)

Debus, Richard [Univ. of California, Riverside, CA (United States)

2012-07-13

The Gordon Research Conference on PHOTOSYNTHESIS was held at Davidson College, Davidson, North Carolina, July 8-13, 2012. The Conference was well-attended with 150 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students. Of the 150 attendees, 65 voluntarily responded to a general inquiry regarding ethnicity which appears on our registration forms. Of the 65 respondents, 20% were Minorities$-$ 5% Hispanic, 15% Asian and 0% African American. Approximately 28% of the participants at the 2012 meeting were women. The Gordon Research Seminar on PHOTOSYNTHESIS held at Davidson College, Davidson, North Carolina, July 7-8, 2012.. The Conference was well-attended with 51 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students. Of the 51 attendees, 22 voluntarily responded to a general inquiry regarding ethnicity which appears on our registration forms. Of the 22 respondents, 14% were Minorities $-$0% Hispanic, 14% Asian and 0% African American. Approximately 35% of the participants at the 2012 meeting were women. Focal points for talks and discussions will include: Artificial photosynthesis and solar energy conversion strategies; Engineering organisms for biofuels and hydrogen production; Electron transport, proton transport, and energy coupling; Photoprotection mechanisms; Photosynthetic reaction center structure and function, including rewiring reaction centers for artificial photosynthesis; Energy capture and light harvesting solutions, including quantum coherence; Structure of the oxygen evolving complex and the mechanism of oxygen production.

MAGLEV `95. 14th international conference on magnetically levitated systems. Proceedings

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-12-31

The proceedings present the papers of the 14th International Conference on Magnetically Levitated Systems held in Bremen, FRG, in November 1995. For 70 of 74 papers a separate subject analysis has been carried out. 4 papers are not available in the proceedings. (HW)

Evaluating mobile centric information access and interaction compatibility for learning websites

CSIR Research Space (South Africa)

Chipangura, B

2013-11-01

Full Text Available guidelines for One web design, not all websites meet these standards. Research has shown that accessing websites that were designed for desktop computer access on mobile hand held devices results in negative user experience [12]. The reasons... to identify mobile phone accessibility problems of university websites [14, 18]. At organizational level, many universities are struggling with adapting their current desktop-based websites to be accessible on mobile devices [20]. A number...

Multipolarity analysis for {sup 14}C high-energy resonance populated by ({sup 18}O,{sup 16}O) two-neutron transfer reaction

Energy Technology Data Exchange (ETDEWEB)

Carbone, D., E-mail: carboned@lns.infn.it; Cavallaro, M.; Bondì, M.; Agodi, C.; Cunsolo, A. [INFN-Laboratori Nazionali del Sud, Catania (Italy); Cappuzzello, F. [INFN-Laboratori Nazionali del Sud, Catania (Italy); Dipartimento di Fisica e Astronomia, Università di Catania, Catania (Italy); Azaiez, F.; Franchoo, S.; Khan, E. [Institut de Physique Nucleaire, Universitè Paris-Sud, Orsay (France); Bonaccorso, A. [INFN-Sezione di Pisa, Pisa (Italy); Fortunato, L. [Dipartimento di Fisica e Astronomia, Università di Padova, Padova (Italy); INFN-Sezione di Padova, Padova (Italy); Foti, A. [Dipartimento di Fisica e Astronomia, Università di Catania, Catania (Italy); INFN-Sezione di Catania, Catania (Italy); Linares, R.; Lubian, J. [Instituto de Fisica, Universidade Federal Fluminense, Niteroi (Brazil); Scarpaci, J. A. [Centre de Sciences Nucleaires et de Sciences de Matieres, Universitè Paris-Sud, Orsay (France); Vitturi, A. [INFN-Sezione di Padova, Padova (Italy); INFN-Sezione di Catania, Catania (Italy)

2015-10-15

The {sup 12}C({sup 18}O,{sup 16}O){sup 14}C reaction at 84 MeV incident energy has been explored up to high excitation energy of the residual nucleus thanks to the use of the MAGNEX spectrometer to detect the ejectiles. In the region above the two-neutron separation energy, a resonance has been observed at 16.9 MeV. A multipolarity analysis of the cross section angular distribution indicates an L = 0 character for such a transition.

18F-Labelled metomidate analogues as adrenocortical imaging agents

International Nuclear Information System (INIS)

Erlandsson, Maria; Karimi, Farhad; Lindhe, Orjan; Langstroem, Bengt

2009-01-01

Introduction: Two- and one-step syntheses of 18 F-labelled analogues of metomidate, such as 2-[ 18 F]fluoroethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate (1), 2-[ 18 F]fluoroethyl 1-[(1R)-1-(4-chlorophenyl)ethyl]-1H-imidazole-5-carboxylate (2), 2-[ 18 F]fluoroethyl 1-[(1R)-1-(4-bromophenyl)ethyl]-1H-imidazole-5-carboxylate (3), 3-[ 18 F]fluoropropyl 1-[(1R)-1-(4-bromophenyl)ethyl]-1H-imidazole-5-carboxylate (4) and 3-[ 18 F]fluoropropyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate (5) are presented. Methods: Analogues 1-5 were prepared by a two-step reaction sequence that started with the synthesis of either 2-[ 18 F]fluoroethyl 4-methylbenzenesulfonate or 3-[ 18 F]fluoropropyl 4-methylbenzenesulfonate. These were used as 18 F-alkylating agents in the second step, in which they reacted with the ammonium salt of a 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid. One-step-labelling syntheses of 1, 2 and 5 were also explored. Analogues 1-4 were biologically validated by frozen-section autoradiography and organ distribution. Metabolite analysis was performed for 2 and 3. Results: The radiochemical yield of the two-step synthesis was in the range of 10-29% and that of the one-step synthesis was 25-37%. Using microwave irradiation in the one-step synthesis of 1 and 2 increased the radiochemical yield to 46±3% and 79±30%, respectively. Conclusion: Both the frozen-section autoradiography and organ distribution results indicated that analogue 2 has a potential as an adrenocortical imaging agent, having the highest degree of specific adrenal binding and best ratio of adrenal to organ uptake among the compounds studied.

Annual report of Radiation Effects Research Foundation, April 1, 1988 - March 31, 1989

International Nuclear Information System (INIS)

1990-01-01

This annual report summarizes the research activities of the Radiation Effects Research Foundation in the fiscal year 1988. Outcome of the work is presented, covering the two major workshops for 'immunology' and for 'radiation-induced carcinogenesis' which were held in Hiroshima on November 28-29, 1988, and on March 16-18, 1989, respectively. Study meeting of 'medical radiation research program' and Japan-the U.S. joint meeting of 'DS 86' are reported, as well as the other scientific lectures and campus study seminars. Included are research abstracts published by the Research Foundation staff. The bibliography of papers, published in scientific journals and presented in scientific meetings, is provided. Appendices give the details of the aforementioned workshops, the continuing research issues, and the personnel list of the Radiation Effects Research Foundation. (N.K.)

29 CFR 1602.14 - Preservation of records made or kept.

Science.gov (United States)

2010-07-01

... RECORDKEEPING AND REPORTING REQUIREMENTS UNDER TITLE VII, THE ADA AND GINA Recordkeeping by Employers § 1602.14... Commission or the Attorney General, against an employer under title VII or the ADA, the respondent employer... positions similar to that held or sought by the aggrieved person and application forms or test papers...

21 CFR 14.22 - Meetings of an advisory committee.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Meetings of an advisory committee. 14.22 Section... of, and with an agenda approved by, the designated Federal employee or alternate. No meeting may be held in the absence of the designated Federal employee. (1) If any matter is added to the agenda after...

Research and Development Program in Reactor Diagnostics and Monitoring with Neutron Noise Methods, Stage 18

International Nuclear Information System (INIS)

Pazsit, Imre; Nam, Tran Hoai; Dykin, Victor; Jonsson, Anders

2013-01-01

This report constitutes Stage 18 of a long-term research and development program concerning the development of diagnostics and monitoring methods for nuclear reactors. The objective of the research program is to contribute to the strategic research goal of competence and research capacity by building up competence within the Department of Nuclear Engineering at Chalmers University of Technology, regarding reactor physics, reactor dynamics and noise diagnostics. The purpose is also to contribute to the research goal of giving a basis for SSM's supervision by developing methods for identification and localization of perturbations in reactor cores. Results up to Stage 17 were reported in SKI and SSM reports, as listed in the report's summary

Design, Research, and Design Research: Synergies and Contradictions

Science.gov (United States)

Nelson, Wayne A.

2013-01-01

Notions of design, research, and design research in the field of educational technology are quite different from conceptualizations held by other design fields. Examining the ways that research is conducted and used in educational technology in comparison to other design fields can provide novel insights into how research and design practice can…

Bulimia nerviosa y factores de riesgo asociados en adolescentes escolarizados de 14 a 18 años en Barranquilla (Colombia

Directory of Open Access Journals (Sweden)

Mariela Borda Pérez

2015-01-01

Full Text Available Objetivo: establecer la prevalencia de riesgo de bulimia y de factores de riesgo asociados en adolecentes escolarizados de 14 a 18 años de Barranquilla. Materiales y métodos: Estudio transversal partir de una muestra representativa de escolares de cuatro establecimientos educativos de Barranquilla. Participaron 149 sujetos de 14 a 18 años. Se aplicó instrumento para determinar imagen corporal y bulimia (Body Shape Questionarie, el Bulimia Test of Edinburgh, Test de Rosemberg y DASS21, se estimó IMC y se empleó un cuestionario para determinantes personales. Resultados: La prevalencia de riesgo de bulimia fue del 44,3 %. El perfil identifica preferencialmente a 51,3 % mujeres, una de cada cuatro con sobrepeso, y de ellos, el 53 % tenía 16 años o más. Las características relevantes: 18,2 % consumía diuréticos y laxantes para bajar de peso; el 40,9 % tenía problemas económicos; el 56 % manifestó ansiedad; el 53 % depresión y el 53 % insatisfacción con su imagen corporal. Se observó tendencia a la asociación con: sobrepeso, saltar comidas con frecuencia, consumir tres comidas y picar, consumir tres comidas, emplear diuréticos o laxantes para bajar de peso, ansiedad, depresión, estrés e insatisfacción corporal; se obtuvieron razones de disparidad significantes y probabilidad del chi-cuadrado menor de 0.05. Conclusión: El riesgo de bulimia se presentó preferencialmente en el grupo de ≥ 16 años, en mujeres y en el estrato medio. Se aprecia una asociación estadística con sobrepeso saltar comidas con frecuencia, consumir tres comidas y picar, consumir tres comidas, emplear diuréticos o laxantes para bajar de peso, ansiedad, depresión, estrés e insatisfacción corporal.

Self-confidence and level of knowledge after cardiopulmonary resuscitation training in 14 to 18-year-old schoolchildren: A randomised-interventional controlled prospective study in secondary schools in Germany.

Science.gov (United States)

Wingen, Sabine; Schroeder, Daniel C; Ecker, Hannes; Steinhauser, Susanne; Altin, Sibel; Stock, Stephanie; Lechleuthner, Alex; Hohn, Andreas; Böttiger, Bernd W

2018-01-02

Education of schoolchildren in cardiopulmonary resuscitation (CPR) is a strategic goal for improvement of bystander CPR in society. The primary objective was to analyse the impact of CPR training on the resuscitation knowledge and self-confidence of secondary schoolchildren. In addition, independent predictors of improved CPR knowledge and self-confidence were investigated. Prospective, randomised-interventional controlled study. Four secondary schools in Germany. Four hundred and twenty-four schoolchildren aged from 14 to 18 years were included into the study. Fifty-one percent were female, and 33% had an immigrant background. The intervention group received a 90-min CPR training session, whereas controls had no intervention. Levels of knowledge and self-confidence in initiating CPR were analysed by a study questionnaire before (t0), 90 min after (t1) and 6 months after training (t2). Based on the evaluation of study questionnaires, the primary endpoint was to determine the development of resuscitation knowledge and self-confidence in initiating cardiopulmonary resuscitation at survey time-points t0, t1 and t2. Schoolchildren in the intervention group (n=207) showed a significantly higher level of knowledge (P CPR training improves the level of knowledge and self-confidence in 14 to 18-year-old schoolchildren. Older schoolchildren are more likely to have increased self-confidence with respect to initiating CPR. Schoolchildren with an immigrant background showed a significantly lower increase in their level of knowledge and self-confidence compared with native children. Adaptation and simplification of teaching materials and further research on educational methods for CPR are urgently needed to enable a sustainable approach to teaching CPR, which also produces a long-lasting effect in the entire population.

Proceedings of the tenth Symposium of Atomic Energy Research. V. II

Energy Technology Data Exchange (ETDEWEB)

Vidovszky, I [ed.

2000-10-01

The present volume contains 80 papers, presented on the tenth Symposium of Atomic Energy Research, held in Moscow, Russia, 18-22 September 2000. The papers are presented in their original form, i. e. no corrections or modifications were carried out. The content of this volume is divided into thematic groups: Core Operation, Fuel Management and Design, Spectral and Core Calculation Methods, Spent Fuel, Transmutations, Core Monitoring, Surveillance and Testing, Neutron Kinetics and reactor Dynamics Methods, Safety Issues and Analysis, Rod Drop Reactivity Measurements, according to the presentation sequence on the Symposium.

Proceedings of the tenth Symposium of Atomic Energy Research. V. II

International Nuclear Information System (INIS)

Vidovszky, I.

2000-10-01

The present volume contains 80 papers, presented on the tenth Symposium of Atomic Energy Research, held in Moscow, Russia, 18-22 September 2000. The papers are presented in their original form, i. e. no corrections or modifications were carried out. The content of this volume is divided into thematic groups: Core Operation, Fuel Management and Design, Spectral and Core Calculation Methods, Spent Fuel, Transmutations, Core Monitoring, Surveillance and Testing, Neutron Kinetics and reactor Dynamics Methods, Safety Issues and Analysis, Rod Drop Reactivity Measurements, according to the presentation sequence on the Symposium

Proceedings of the Tenth Symposium of Atomic Energy Research. V. I

International Nuclear Information System (INIS)

Vidovszky, I.

2000-10-01

The present volume contains 80 papers, presented on the tenth Symposium of Atomic Energy Research, held in Moscow, Russia, 18-22 October 2000. The papers are presented in their original form, i. e. no corrections or modifications were carried out. The content of this volume is divided into thematic groups: Core Operation, Fuel Management and Design, Spectral and Core Calculation Methods, Spent Fuel, Transmutations, Core Monitoring, Surveillance and Testing, Neutron Kinetics and reactor Dynamics Methods, Safety Issues and Analysis, Rod Drop Reactivity Measurements, according to the presentation sequence on the Symposium

The improved syntheses of 5-substituted 2'-[18F]fluoro-2'-deoxy-arabinofuranosyluracil derivatives ([18F]FAU, [18F]FEAU, [18F]FFAU, [18F]FCAU, [18F]FBAU and [18F]FIAU) using a multistep one-pot strategy

International Nuclear Information System (INIS)

Cai Hancheng; Li Zibo; Conti, Peter S.

2011-01-01

]FEAU, [ 18 F]FFAU, [ 18 F]FCAU, [ 18 F]FBAU and [ 18 F]FIAU more accessible for preclinical and clinical research.

18F based radiopharmaceuticals and automation of synthesis. New 18F radiopharmaceuticals

International Nuclear Information System (INIS)

Garg, P.K.; Garg, S.

2007-01-01

Fluorine-18 is one of the most commonly used positron emitting isotopes for clinical and research needs with a physical half-life of 110 min. PET isotopes deposit higher radiation absorbed dose than nuclear medicine isotopes. Because of their relatively short half-life, larger quantities of these isotopes are used at the start of synthesis. Therefore, increased shielding and remote automated synthesis are essential for their safe handling. Unlike other radiopharmaceuticals, it is not practical to produce PET radiopharmaceuticals at a central location for subsequent distribution to clinical and research facilities around the country. This limitation compels various academic and research facilities to manufacture their own PET radiopharmaceuticals for in-house use. For multiple reasons, 18 F fluorodeoxyglucose ([ 18 F]FDG) is one of the most commonly used radiopharmaceuticals. The synthesis of [ 18 F]FDG has been optimized and automated, thus allowing independent laboratories to produce this radiopharmaceutical safely. Nonetheless, these laboratories should acquire resources and expertise to fulfil ever increasing regulatory requirements for the safe production and usage of PET radiopharmaceuticals. In addition to [ 18 F]FDG, a wide array of new and novel radiotracers is being developed to explore various biological processes. This paper emphasizes the fact that it is possible to accomplish research and fulfil clinical needs within an academic setting with modest resources. A careful assessment of the need for due diligence in radiation safety issues is very important for the longevity of any PET research endeavour. (author)

What We've Learned, What We Still Need to Know: Insights from the Credit When It's Due (CWID) Research Meeting in Salt Lake City

Science.gov (United States)

Bragg, Debra D.

2016-01-01

On February 18-19, 2016, representatives of 10 states participating in the Credit When It's Due (CWID) initiative attended a convening held at the University of Utah. The meeting was led by the CWID Research Team and sponsored by the Bill & Melinda Gates Foundation and The Kresge Foundation, on behalf of the CWID Funders Collaborative. The…

The network researchers' network

DEFF Research Database (Denmark)

Henneberg, Stephan C.; Jiang, Zhizhong; Naudé, Peter

2009-01-01

The Industrial Marketing and Purchasing (IMP) Group is a network of academic researchers working in the area of business-to-business marketing. The group meets every year to discuss and exchange ideas, with a conference having been held every year since 1984 (there was no meeting in 1987). In thi......The Industrial Marketing and Purchasing (IMP) Group is a network of academic researchers working in the area of business-to-business marketing. The group meets every year to discuss and exchange ideas, with a conference having been held every year since 1984 (there was no meeting in 1987......). In this paper, based upon the papers presented at the 22 conferences held to date, we undertake a Social Network Analysis in order to examine the degree of co-publishing that has taken place between this group of researchers. We identify the different components in this database, and examine the large main...

International Conference held at the University of Alberta

CERN Document Server

Strobeck, Curtis

1983-01-01

This volume contains the Proceedings of the International Conference in Population Biology held at The University of Alberta, Edmonton, Canada from June 22 to June 30, 1982. The Conference was sponsored by The University of Alberta and The Canadian Applied Mathematics Society, and overlapped with the summer meeting of CAMS. The main objectives of this Conference were: to bring mathematicians and biologists together so that they may interact for their mutual benefit; to bring those researchers interested in modelling in ecology and those interested in modelling in genetics together; to bring in keynote speakers in the delineated areas; to have sessions of contributed papers; and to present the opportunity for researchers to conduct workshops. With the exception of the last one, the objec­ tives were carried out. In order to lend some focus to the Conference, the following themes were adopted: models of species growth, predator-prey, competition, mutualism, food webs, dispersion, age structure, stability, evol...

Report on the International Rarefied Gas Dynamics Symposium (29th) held in Xi’an, China on 13-18 July 2014

Science.gov (United States)

2014-11-21

E. Knuth (USA) G.M. Kremer ( Brazil ) E.V. Kustova (Russia) D. Levin (USA) E.P. Muntz (USA) T. Niimi (Japan) A.K. Rebrov (Russia) A. Santos (Spain) B...also provided a special shuttle service from the airport to the Hilton Hotel where the symposium was being held. Throughout the conference the...0 0 Israel 2 0 0 Australia 2 0 1 Kazakhstan 2 0 1 Switzerld. 1 2 1 Canada 1 3 0 UK 1 1 1 Greece 1 0 0 Iran 1 0 0 Netherlands 1 0 0 Spain 1 0 0 Brazil

25 Years of Research in Earth Physics and One Century of Seismology in Romania

International Nuclear Information System (INIS)

Marmureanu, Gh.

2002-01-01

The conference '25 Years of Research in Earth Physics and One Century of Seismology in Romania' held at Bucharest, Romania on September 27-29, 2002 was structured as follows: 1. Keynote lectures (4 papers); Section 1 - Exchange of data and improvement of earthquake monitoring during the last 25 years (6 papers); Section 2 - Study of the seismic source (5 papers); Section 3 - Seismotectonics and geodynamics of the Carphato - Balkan area (16 papers); Section 4 - Seismic hazard assesment (14 papers); Section 5 - Earthquake prediction research (7 papers); Section 6 - Lessons from earthquake damage and policies for seismic risk mitigation (3 papers)

FAA/NASA Joint University Program for Air Transportation Research: 1993-1994

Science.gov (United States)

Hueschen, Richard M. (Compiler)

1995-01-01

This report summarizes the research conducted during the academic year 1993-1994 under the NASA/FAA sponsored Joint University Program for Air Transportation Research. The year end review was held at Ohio University, Athens, Ohio, July 14-15, 1994. The Joint University Program is a coordinated set of three grants sponsored by NASA Langley Research Center and the Federal Aviation Administration, one each with the Massachusetts Institute of Technology (NGL-22-009-640), Ohio University (NGR-36-009-017), and Princeton University (NGL-31-001-252). Completed works, status reports, and annotated bibliographies are presented for research topics which include navigation, guidance and control theory and practice, aircraft performance, human factors, and expert systems concepts applied to aircraft and airport operations. An overview of the year's activities for each university is also presented.

Fifteenth nuclear accident dosimetry intercomparison study: August 14--22, 1978

International Nuclear Information System (INIS)

Sims, C.S.

1979-05-01

The fifteenth in the continuing series of Nuclear Accident Dosimetry Intercomparison Studies was held August 14--22, 1978 at the Oak Ridge National Laboratory. The Health Physics Research Reactor, operated in the pulse mode, served as the radiation source. Using different shielding configurations, nuclear accidents with three different neutron and gamma spectra were simulated. Participants from 19 organizations, the most in the history of the studies, exposed dosimeters set up as area monitors as well as dosimeters mounted on phantoms for personnel monitoring. Although many participants performed accurate measurements, the composite dose results, in the majority of cases, failed to meet established nuclear criticality accident dosimetry guidelines which suggest accuracies of +- 25% for neutron dose and +- 20% for gamma dose. This indicates that many participants need to improve their dosimetry systems, their analytical techniques, or both

Human embryonic stem cells and good manufacturing practice: Report of a 1- day workshop held at Stem Cell Biology Research Center, Yazd, 27th April 2017

Directory of Open Access Journals (Sweden)

Fatemeh Akyash

2017-09-01

Full Text Available This report explains briefly the minutes of a 1-day workshop entitled; “human embryonic stem cells (hESCs and good manufacturing practice (GMP” held by Stem Cell Biology Research Center based in Yazd Reproductive Sciences Institute at Shahid Sadoughi University of Medical Sciences, Yazd, Iran on 27th April 2017. In this workshop, in addition to the practical sessions, Prof. Harry D. Moore from Centre for Stem Cell Biology, University of Sheffield, UK presented the challenges and the importance of the biotechnology of clinical-grade human embryonic stem cells from first derivation to robust defined culture for therapeutic applications.

Human embryonic stem cells and good manufacturing practice: Report of a 1- day workshop held at Stem Cell Biology Research Center, Yazd, 27th April 2017.

Science.gov (United States)

Akyash, Fatemeh; Sadeghian-Nodoushan, Fatemeh; Tahajjodi, Somayyeh Sadat; Nikukar, Habib; Farashahi Yazd, Ehsan; Azimzadeh, Mostafa; D Moore, Harry; Aflatoonian, Behrouz

2017-05-01

This report explains briefly the minutes of a 1-day workshop entitled; "human embryonic stem cells (hESCs) and good manufacturing practice (GMP)" held by Stem Cell Biology Research Center based in Yazd Reproductive Sciences Institute at Shahid Sadoughi University of Medical Sciences, Yazd, Iran on 27 th April 2017. In this workshop, in addition to the practical sessions, Prof. Harry D. Moore from Centre for Stem Cell Biology, University of Sheffield, UK presented the challenges and the importance of the biotechnology of clinical-grade human embryonic stem cells from first derivation to robust defined culture for therapeutic applications.

FAIRNESS 2016 [4. workshop for young scientists with research interests focused on physics at FAIR (Facility for Antiproton and Ion Research), Garmisch-Partenkirchen (Germany), 14-19 Feb 2016

International Nuclear Information System (INIS)

2016-01-01

FAIRNESS 2016 was the fourth edition in a series of workshops designed to bring together excellent international young scientists with research interests focused on physics at FAIR (Facility for Antiproton and Ion Research) and was held on February 14-19 2016 in Garmisch-Partenkirchen, Germany. The topics of the workshops cover a wide range of aspects in both theoretical developments and current experimental status, concentrated around the four scientific pillars of FAIR. FAIR is a new accelerator complex with brand new experimental facilities, that is currently being built next to the existing GSI facility close to Darmstadt, Germany. The spirit of the conference is to bring together young scientists, e.g. young non-tenured scientists, postdocs and advanced PhD students to present their work, to foster active informal discussions and build up networks. Every participant in the meeting with the exception of the organizers gives an oral presentation, and all sessions are followed by an hour long discussion period. During the talks, questions are anonymously collected in a box to stimulate discussions. The broad physics program at FAIR is reflected in the wide range of topics covered by the workshop: • Atomic and plasma physics, biophysics, material sciences and applications • Nuclear structure, astrophysics and reactions • Physics of hot and dense nuclear matter, QCD phase transitions and critical point • Hadron Spectroscopy, Hadrons in matter and Hypernuclei • Experimental programs APPA, CBM, HADES, PANDA, NUSTAR, as well as BES, NICA and the RHIC beam energy scan For these different areas one invited speaker was selected to give a longer introductory presentation. The write-ups of the talks presented at FAIRNESS 2016 are the content of this issue of Journal of Physics: Conference Series and have been refereed according to the IOP standard for peer review. This issue constitutes therefore a collection of the forefront of research that is dedicated to the

In vivo evaluation of 2'-deoxy-2'-[{sup 18}F]fluoro-5-iodo-1-{beta}-D-arabinofuranosyluracil ([{sup 18}F]FIAU) and 2'-deoxy-2'-[{sup 18}F]fluoro-5-ethyl-1-{beta}-D-arabinofuranosyluracil ([{sup 18}F]FEAU) as markers for suicide gene expression

Energy Technology Data Exchange (ETDEWEB)

Alauddin, Mian M. [University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd. T8.3895, P.O. Box 059, Houston, TX (United States); Shahinian, Antranic; Park, Ryan; Fissekis, John D.; Conti, Peter S. [University of Southern California, PET Imaging Science Center, Keck School of Medicine, Los Angeles, CA (United States); Tohme, Michel [University of Southern California, PET Imaging Science Center, Keck School of Medicine, Los Angeles, CA (United States); Department of Biomedical Engineering, UC Davis, Davis, CA (United States)

2007-06-15

FIAU and FEAU were evaluated in vitro and in vivo as markers for HSV1-tk gene expression. In vitro and biodistribution studies were performed in wild type and transduced HT-29 cells using [{sup 14}C]FIAU and [{sup 3}H]FEAU. PET imaging was performed using [{sup 18}F]FIAU and [{sup 18}F]FEAU. In vitro uptake of [{sup 14}C]FIAU in tk-positive cells was 39-fold, 49-fold, and 43-fold higher (p < 0.001) than in wild type cells at 30, 60, and 120 min, respectively. Uptake of [{sup 3}H]FEAU in transduced cells was 46-fold, 62-fold, and 121-fold higher (p < 0.001) than in wild type cells at the same time points. In vivo uptake of [{sup 14}C]FIAU at 2 h in HSV1-tk positive tumors was 15.48 {+-} 3.94, 6.7-fold higher (p < 0.001) than in wild type tumors. Uptake of [{sup 3}H]FEAU in transduced tumors was 9.98 {+-} 1.99, 5.0-fold higher (p < 0.001) than in wild type tumors. Micro-PET images using [{sup 18}F]FIAU and [{sup 18}F]FEAU also showed very high uptake in HSV-tk tumors. [{sup 18}F]FIAU and [{sup 18}F]FEAU appear to be potential PET imaging agents for gene expression. (orig.)

14th ACIS/IEEE International Conference on Software Engineering, Artificial Intelligence, Networking and Parallel/Distributed Computing

CERN Document Server

Studies in Computational Intelligence : Volume 492

2013-01-01

This edited book presents scientific results of the 14th ACIS/IEEE International Conference on Software Engineering, Artificial Intelligence, Networking and Parallel/Distributed Computing (SNPD 2013), held in Honolulu, Hawaii, USA on July 1-3, 2013. The aim of this conference was to bring together scientists, engineers, computer users, and students to share their experiences and exchange new ideas, research results about all aspects (theory, applications and tools) of computer and information science, and to discuss the practical challenges encountered along the way and the solutions adopted to solve them. The conference organizers selected the 17 outstanding papers from those papers accepted for presentation at the conference.  

13 CFR 120.1850 - Will the Collateral be held by SBA?

Science.gov (United States)

2010-01-01

... Loan Program) § 120.1850 Will the Collateral be held by SBA? Yes, SBA or its expressly authorized agent... all Collateral for SISMBD Loans in a custodial account. Certificates held as Collateral must be in... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Will the Collateral be held by SBA...

Research and Development Program in Reactor Diagnostics and Monitoring with Neutron Noise Methods. Stages 14 and 15

International Nuclear Information System (INIS)

Pazsit, Imre; Wihlstrand, Gustav; Tambouratzis, Tatiana; Jonsson, Anders; Dahl, Berit

2009-12-01

This report constitutes Stages 14 and 15 of a long-term research and development program concerning the development of diagnostics and monitoring methods for nuclear reactors. Stage 14 was a full one-year project, whereas Stage 15 consisted of a half-year project. The program executed in Stages 14 and 15 consists of the following three parts: - Study of criticality, neutron kinetics and neutron noise in molten salt reactors (MSR) (Stages 14 and 15); - An overview and introduction to fuzzy logics (Stage 14), and an application to two-phase flow identification (Stage 15) - Preparations for and execution of an IAEA-ICTP workshop on Neutron fluctuations, reactor noise and their applications in nuclear reactors (Stage 14)

Research and Development Program in Reactor Diagnostics and Monitoring with Neutron Noise Methods. Stages 14 and 15

Energy Technology Data Exchange (ETDEWEB)

Pazsit, Imre; Wihlstrand, Gustav; Tambouratzis, Tatiana; Jonsson, Anders; Dahl, Berit (Chalmers Univ. of Technology, Dept. of Nuclear Engineering, SE-412 96 Goeteborg (Sweden))

2009-12-15

This report constitutes Stages 14 and 15 of a long-term research and development program concerning the development of diagnostics and monitoring methods for nuclear reactors. Stage 14 was a full one-year project, whereas Stage 15 consisted of a half-year project. The program executed in Stages 14 and 15 consists of the following three parts: - Study of criticality, neutron kinetics and neutron noise in molten salt reactors (MSR) (Stages 14 and 15); - An overview and introduction to fuzzy logics (Stage 14), and an application to two-phase flow identification (Stage 15) - Preparations for and execution of an IAEA-ICTP workshop on Neutron fluctuations, reactor noise and their applications in nuclear reactors (Stage 14)

Staging and Functional Characterization of Pheochromocytoma and Paraganglioma by 18F-Fluorodeoxyglucose (18F-FDG) Positron Emission Tomography

Science.gov (United States)

Timmers, Henri J. L. M.; Chen, Clara C.; Carrasquillo, Jorge A.; Whatley, Millie; Ling, Alexander; Eisenhofer, Graeme; King, Kathryn S.; Rao, Jyotsna U.; Wesley, Robert A.; Adams, Karen T.

2012-01-01

Background Pheochromocytomas and paragangliomas (PPGLs) are rare tumors of the adrenal medulla and extra-adrenal sympathetic chromaffin tissues; their anatomical and functional imaging are critical to guiding treatment decisions. This study aimed to compare the sensitivity and specificity of 18F-fluorodeoxyglucose positron emission tomography with computed tomography (18F-FDG PET/CT) for tumor localization and staging of PPGLs with that of conventional imaging by [123I]-metaiodobenzylguanidine single photon emission CT (123I-MIBG SPECT), CT, and magnetic resonance imaging (MRI). Methods A total of 216 patients (106 men, 110 women, aged 45.2 ± 14.9 years) with suspected PPGL underwent CT or MRI, 18F-FDG PET/CT, and 123I-MIBG SPECT/CT. Sensitivity and specificity were measured as endpoints and compared by the McNemar test, using two-sided P values only. Results Sixty (28%) of patients had nonmetastatic PPGL, 95 (44%) had metastatic PPGL, and 61 (28%) were PPGL negative. For nonmetastatic tumors, the sensitivity of 18F-FDG was similar to that of 123I-MIBG but less than that of CT/MRI (sensitivity of 18F-FDG = 76.8%; of 123I-MIBG = 75.0%; of CT/MRI = 95.7%; 18F-FDG vs 123I-MIBG: difference = 1.8%, 95% confidence interval [CI] = −14.8% to 14.8%, P = .210; 18F-FDG vs CT/MRI: difference = 18.9%, 95% CI = 9.4% to 28.3%, P < .001). The specificity was 90.2% for 18F-FDG, 91.8% for 123I-MIBG, and 90.2% for CT/MRI. 18F-FDG uptake was higher in succinate dehydrogenase complex– and von Hippel–Lindau syndrome–related tumors than in multiple endocrine neoplasia type 2 (MEN2) related tumors. For metastases, sensitivity was greater for 18F-FDG and CT/MRI than for 123I-MIBG (sensitivity of 18F-FDG = 82.5%; of 123I-MIBG = 50.0%; of CT/MRI = 74.4%; 18F-FDG vs 123I-MIBG: difference = 32.5%, 95% CI = 22.3% to 42.5%, P < .001; CT/MRI vs 123I-MIBG: difference = 24.4%, 95% CI = 11.3% to 31.6%, P < .001). For bone metastases, 18F-FDG was more sensitive than CT/MRI (sensitivity of 18

14. Meeting of the North and Northeast physicists. Program and abstracts

International Nuclear Information System (INIS)

1996-01-01

These proceedings contain abstracts of oral and panel presentations carried out during the 14 Meeting of physicists of North and Northeast held in Aracaju, State of Sergipe, Brazil. While covering different areas of physics, they emphasized the condensed matter, statistical physics and nuclear physics in their theoretical and experimental aspects

[14C]Fluciclovine (alias anti-[14C]FACBC) uptake and ASCT2 expression in castration-resistant prostate cancer cells

International Nuclear Information System (INIS)

Ono, Masahiro; Oka, Shuntaro; Okudaira, Hiroyuki; Nakanishi, Takeo; Mizokami, Atsushi; Kobayashi, Masato; Schuster, David M.; Goodman, Mark M.; Shirakami, Yoshifumi; Kawai, Keiichi

2015-01-01

Introduction: trans-1-Amino-3-[ 18 F]fluorocyclobutanecarboxylic acid ([ 18 F]fluciclovine, also known as anti-[ 18 F]FACBC), is a tracer for positron emission tomography (PET) imaging for detection of tumors such as prostate cancer (PCa). Our previous study showed that ASCT2 (Na + -dependent amino acid transporter (AAT)) mediates fluciclovine uptake in androgen-dependent PCa cells; its expression is influenced by androgen, a key hormone in the progression of primary PCa and castration-resistant prostate cancer (CRPC). In this study, we investigated the uptake mechanisms and feasibility of [ 18 F]fluciclovine for CRPC in the androgen-dependent PCa cell line LNCaP and LNCaP-derivatives LNCaP-SF and LN-REC4. Methods: LNCaP-SF was established after long-term cultivation of LNCaP in steroid-free conditions, and LN-Pre and LN-REC4 were established from LNCaP inoculated in intact and castrated severe combined immunodeficient mice, respectively. Uptake and competitive inhibition experiments were performed with trans-1-amino-3-fluoro[1- 14 C]cyclobutanecarboxylic acid ([ 14 C]fluciclovine) to characterize the involvement of AATs in androgen-dependent PCa (LNCaP and LN-Pre) and CRPC-like (LNCaP-SF and LN-REC4) cell lines. AAT expression was analyzed by Western blotting, and [ 14 C]fluciclovine uptake in androgen-dependent PCa and CRPC-like cell lines were investigated in the presence or absence of dihydrotestosterone (DHT). Results: The contribution of Na + -dependent AATs to [ 14 C]fluciclovine uptake in all cell lines was 88−98%, and [ 14 C]fluciclovine uptake was strongly inhibited by L-glutamine and L-serine, the substrates for Na + -dependent alanine-serine-cysteine (system ASC) AATs, in the presence of Na + . DHT enhanced ASCT2 expression in LNCaP, LN-Pre, and LN-REC4, but not in LNCaP-SF, and the responses of ASCT2 expression to DHT correlated with [ 14 C]fluciclovine uptake. Conclusions: System ASC, especially ASCT2, could play a major role in [ 14 C

Annual report of National Institute of Radiological Sciences of the fiscal year 1986

International Nuclear Information System (INIS)

1987-11-01

In fiscal year 1986, this Institute was alloted the budget of 6.4 billion yen, 16 % more as compared with the previous year. It was for promoting the various facilities for internal exposure experiment, the basic design of a heavy particle beam cancer treatment apparatus, the additional construction of the cyclotron building and other various works. As the research activities, the results of high level were obtained in four special researches on tritium, probabilistic effect, exposure evaluation and heavy particles. The case of neutron therapy has reached 1500 cases, and the adaptation to the therapy became clearer. The 14th environment seminar was held in December with the title 'Dynamic analysis of contamination mechanism in marine living things'. Also the 18th symposium on 'New development in chromosome research' was held. Due to the Chernoby1-4 accident on April 26, the medical examination of the travelers to USSR was carried out at international airports, and the report was made. As the program of the Regional Cooperation Agreement of IAEA, the training course for radiation therapy and the cooperation with the research on the diagnostic techniques of nuclear medicine were carried out. 39 personnel carried out international activities, and 63 foreign researchers visited the Institute. (K.I.)

PROCEEDINGS OF THE 2001 NATIONAL OILHEAT RESEARCH ALLIANCE TECHNOLOGY CONFERENCE HELD AT BROOKHAVEN NATIONAL LABORATORY, UPTON, N.Y., APRIL 30 - MAY 1, 2001.

Energy Technology Data Exchange (ETDEWEB)

MCDONALD, R.J.

2001-04-30

BNL is proud to acknowledge all of our 2001 sponsors, with their help and support this has correctly become an oilheat industry conference. It is quite gratifying to see an industry come together to help support an activity like the technology conference, for the benefit of the industry as a whole and to celebrate the beginning of the National Oilheat Research Alliance. This meeting is the fourteenth oil heat industry technology conference to be held since 1984 and the first under a new name, NORA, the National Oilheat research Alliance, and the very first in the new century. The conference is a very important part of the effort in technology transfer, which is supported by the Oilheat Research Program. The Oilheat Research Program at BNL is under the newly assigned program management at the Office of Power Technology within the US DOE. The foremost reason for the conference is to provide a platform for the exchange of information and perspectives among international researchers, engineers, manufacturers, service technicians, and marketers of oil-fired space-conditioning equipment. The conference provides a conduit by which information and ideas can be exchanged to examine present technologies, as well as helping to develop the future course for oil heating advancement. These conferences also serve as a stage for unifying government representatives, researchers, fuel oil marketers, and other members of the oil-heat industry in addressing technology advancements in this important energy use sector. The specific objectives of the conference are to: (1) Identify and evaluate the current state-of-the-art and recommend new initiatives for higher efficiency, a cleaner environment, and to satisfy consumer needs cost-effectively, reliably, and safely; (2) Foster cooperative interactions among federal and industrial representatives for the common goal of sustained economic growth and energy security via energy conservation. Seventeen technical presentations will be made

{sup 18}F-Labelled metomidate analogues as adrenocortical imaging agents

Energy Technology Data Exchange (ETDEWEB)

Erlandsson, Maria; Karimi, Farhad [Department of Biochemistry and Organic Chemistry, Uppsala University, Box 576, S-751 23 Uppsala (Sweden); Lindhe, Orjan [Uppsala Imanet, GE Healthcare, Box 967, S-751 09 Uppsala (Sweden); Langstroem, Bengt [Department of Biochemistry and Organic Chemistry, Uppsala University, Box 576, S-751 23 Uppsala (Sweden)], E-mail: bengt.langstrom@biorg.uu.se

2009-05-15

Introduction: Two- and one-step syntheses of {sup 18}F-labelled analogues of metomidate, such as 2-[{sup 18}F]fluoroethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate (1), 2-[{sup 18}F]fluoroethyl 1-[(1R)-1-(4-chlorophenyl)ethyl]-1H-imidazole-5-carboxylate (2), 2-[{sup 18}F]fluoroethyl 1-[(1R)-1-(4-bromophenyl)ethyl]-1H-imidazole-5-carboxylate (3), 3-[{sup 18}F]fluoropropyl 1-[(1R)-1-(4-bromophenyl)ethyl]-1H-imidazole-5-carboxylate (4) and 3-[{sup 18}F]fluoropropyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate (5) are presented. Methods: Analogues 1-5 were prepared by a two-step reaction sequence that started with the synthesis of either 2-[{sup 18}F]fluoroethyl 4-methylbenzenesulfonate or 3-[{sup 18}F]fluoropropyl 4-methylbenzenesulfonate. These were used as {sup 18}F-alkylating agents in the second step, in which they reacted with the ammonium salt of a 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid. One-step-labelling syntheses of 1, 2 and 5 were also explored. Analogues 1-4 were biologically validated by frozen-section autoradiography and organ distribution. Metabolite analysis was performed for 2 and 3. Results: The radiochemical yield of the two-step synthesis was in the range of 10-29% and that of the one-step synthesis was 25-37%. Using microwave irradiation in the one-step synthesis of 1 and 2 increased the radiochemical yield to 46{+-}3% and 79{+-}30%, respectively. Conclusion: Both the frozen-section autoradiography and organ distribution results indicated that analogue 2 has a potential as an adrenocortical imaging agent, having the highest degree of specific adrenal binding and best ratio of adrenal to organ uptake among the compounds studied.

9 CFR 354.126 - Carcasses held for further examination.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Carcasses held for further examination. 354.126 Section 354.126 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF... Inspection § 354.126 Carcasses held for further examination. Each carcass, including all parts thereof, in...

9 CFR 381.77 - Carcasses held for further examination.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Carcasses held for further examination. 381.77 Section 381.77 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF... Carcasses and Parts § 381.77 Carcasses held for further examination. Each carcass, including all parts...

Report of the Interagency Optical Network Testbeds Workshop 2 September 12-14, 2006 NASA Ames Research Center

Energy Technology Data Exchange (ETDEWEB)

Joe Mambretti Richard desJardins

2006-05-01

A new generation of optical networking services and technologies is rapidly changing the world of communications. National and international networks are implementing optical services to supplement traditional packet routed services. On September 12-14, 2005, the Optical Network Testbeds Workshop 2 (ONT2), an invitation-only forum hosted by the NASA Research and Engineering Network (NREN) and co-sponsored by the Department of Energy (DOE), was held at NASA Ames Research Center in Mountain View, California. The aim of ONT2 was to help the Federal Large Scale Networking Coordination Group (LSN) and its Joint Engineering Team (JET) to coordinate testbed and network roadmaps describing agency and partner organization views and activities for moving toward next generation communication services based on leading edge optical networks in the 3-5 year time frame. ONT2 was conceived and organized as a sequel to the first Optical Network Testbeds Workshop (ONT1, August 2004, www.nren.nasa.gov/workshop7). ONT1 resulted in a series of recommendations to LSN. ONT2 was designed to move beyond recommendations to agree on a series of “actionable objectives” that would proactively help federal and partner optical network testbeds and advanced research and education (R&E) networks to begin incorporating technologies and services representing the next generation of advanced optical networks in the next 1-3 years. Participants in ONT2 included representatives from innovative prototype networks (Panel A), basic optical network research testbeds (Panel B), and production R&D networks (Panels C and D), including “JETnets,” selected regional optical networks (RONs), international R&D networks, commercial network technology and service providers (Panel F), and senior engineering and R&D managers from LSN agencies and partner organizations. The overall goal of ONT2 was to identify and coordinate short and medium term activities and milestones for researching, developing, identifying

Cyclic nucleotide dependent dephosphorylation of regulator of G-protein signaling 18 in human platelets.

LENUS (Irish Health Repository)

Gegenbauer, Kristina

2013-11-01

Regulator of G-protein signaling 18 (RGS18) is a GTPase-activating protein that turns off Gq signaling in platelets. RGS18 is regulated by binding to the adaptor protein 14-3-3 via phosphorylated serine residues S49 and S218 on RGS18. In this study we confirm that thrombin, thromboxane A2, or ADP stimulate the interaction of RGS18 and 14-3-3 by increasing the phosphorylation of S49. Cyclic AMP- and cyclic GMP-dependent kinases (PKA, PKG) inhibit the interaction of RGS18 and 14-3-3 by phosphorylating S216. To understand the effect of S216 phosphorylation we studied the phosphorylation kinetics of S49, S216, and S218 using Phos-tag gels and phosphorylation site-specific antibodies in transfected cells and in platelets. Cyclic nucleotide-induced detachment of 14-3-3 from RGS18 coincides initially with double phosphorylation of S216 and S218. This is followed by dephosphorylation of S49 and S218. Dephosphorylation of S49 and S218 might be mediated by protein phosphatase 1 (PP1) which is linked to RGS18 by the regulatory subunit PPP1R9B (spinophilin). We conclude that PKA and PKG induced S216 phosphorylation triggers the dephosphorylation of the 14-3-3 binding sites of RGS18 in platelets.

14 CFR Section 18 - Objective Classification-Cumulative Effect of Changes in Accounting Principles

Science.gov (United States)

2010-01-01

... of Changes in Accounting Principles Section 18 Section 18 Aeronautics and Space OFFICE OF THE... Objective Classification—Cumulative Effect of Changes in Accounting Principles 98Cumulative Effect of Changes in Accounting Principles. Record here the difference between the amount of retained earnings at...

Accounting Practices Regarding the Non-Current Assets Held for Sale

Directory of Open Access Journals (Sweden)

Marinela Manea

2010-12-01

Full Text Available Generally the non-current assets, and especially the tangible assets, are held by the entity (as it results from their very definition in order to be used in the production of goods or for services, to be rented to the thirds or to be used for administrative purposes during several periods. For the time interval that a non-current asset is not classified as being held for sale, its recognition and implicitly its assessment will be done in accordance with the provisions of the applicable International Financial Reporting Standards; after the classification of the respective asset as being held with the intention of subsequent sale there will be applicable the provisions of the contemporary IFRS norm 5 “Non-current assets held for sale and discontinued activities”.

Eighteenth annual risk reduction engineering laboratory research symposium

International Nuclear Information System (INIS)

Anon.

1992-01-01

The Eighteenth Annual Risk Reduction Engineering Laboratory Research Symposium was held in Cincinnati, Ohio, April 14-16, 1992. The purpose of this Symposium was to present the latest significant research findings from ongoing and recently completed projects funded by the Risk Reduction Engineering Laboratory (RREL). These Proceedings are organized into two sections. Sessions A and B, which contain extended abstracts of the paper presentations. A list of poster displays is also included. Subjects include remedial action, treatment, and control technologies for waste disposal, landfill liner and cover systems, underground storage tanks, and demonstration and development of innovative/alternative treatment technologies for hazardous waste. Alternative technology subjects include thermal destruction of hazardous wastes, field evaluations, existing treatment options, emerging treatment processes, waste minimization, and biosystems for hazardous waste destruction

Selected Papers on Ocean-Seismo Acoustics Low-Frequency Underwater Acoustics Based on the SACLANTCEN Contributions to a Symposium Held by SACLANTCEN on 10-14 June 1985

Science.gov (United States)

1986-06-01

Curzi** *SACLANT ASW Research Centre Viale San Bartolomeo 400 1-19026 La Spezia, Italy **Istituto di Geologia Marina Consiglio Nazionale delle Ricerche...In: Convegno sul tema: La Geologia Marina - aspetti di ricerca pura ed applicata. S. Benedetto del Tronto, 16-18 aprile 1984, Ascoli Piceno, Societa

Report on achievements in fiscal 1999. Development of technology to put photovoltaic power generation system into practical use by international cooperation project (Executive Committee meetings for treaty of executing IEA photovoltaic power generation system research cooperation program - IEA/PVPS); 1999 nendo taiyoko hatsuden system jitsuyoka gijutsu kaihatsu. Kokusai kyoryoku jigyo (IEA taiyoko hatsuden system kenkyu kyoryoku program jisshi kyotei (shikko iinkai))

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-03-01

The 13th and 14th Executive Committee meetings were held. The resolutions adopted at the 13th Executive Committee meeting (Lausanne, Switzerland, May 3 through 5, 1999) were the approval of the Task VIII as a new IEA/PVPS task, the feasibility study on large scale photovoltaic power generation utilizing unused land such as desert (the operating agent country being Japan headed by Mr. Kando, chief researcher at NEDO and Professor Kurokawa) and the Task IX, proliferation of photovoltaic power generation under coordination with developing countries (the operating agent country being England headed by Mr. Bernard McNelis (IT Power) and that the task I operating agent country is substituted jointly by the three countries of Australia, Holland and Switzerland for six months. The resolutions adopted at the 14th Executive Committee meeting (Oslo, Norway, October 18 through 20, 1999) were appointing Australia as the Task I operating agent country headed by Mr. G. Watt, setting a web site of IEA/PVPS, issuing the annual report for fiscal 1998 in early 2000, and holding the Executive Committee meetings for fiscal 2000 in Canada (Quebec, April 17 through 19, 2000), and Italy (October 16 through 18, 2000). (NEDO)

Reliability of measuring hip abductor strength following total knee arthroplasty using a hand-held dynamometer.

Science.gov (United States)

Schache, Margaret B; McClelland, Jodie A; Webster, Kate E

2016-01-01

To investigate the test-retest reliability of measuring hip abductor strength in patients with total knee arthroplasty (TKA) using a hand-held dynamometer (HHD) with two different types of resistance: belt and manual resistance. Test-retest reliability of 30 subjects (17 female, 13 male, 71.9 ± 7.4 years old), 9.2 ± 2.7 days post TKA was measured using belt and therapist resistance. Retest reliability was calculated with intra-class coefficients (ICC3,1) and 95% confidence intervals (CI) for both the group average and the individual scores. A paired t-test assessed whether a difference existed between the belt and therapist methods of resistance. ICCs were 0.82 and 0.80 for the belt and therapist resisted methods, respectively. Hip abductor strength increases of 8 N (14%) for belt resisted and 14 N (17%) for therapist resisted measurements of the group average exceeded the 95% CI and may represent real change. For individuals, hip abductor strength increases of 33 N (72%) (belt resisted) and 57 N (79%) (therapist resisted) could be interpreted as real change. Hip abductor strength can be reliably measured using HHD in the clinical setting with the described protocol. Belt resistance demonstrated slightly higher test-retest reliability. Reliable measurement of hip abductor muscle strength in patients with TKA is important to ensure deficiencies are addressed in rehabilitation programs and function is maximized. Hip abductor strength can be reliably measured with a hand-held dynamometer in the clinical setting using manual or belt resistance.

Optimization of synthesis and quality control procedures for the preparation of 18F and 123I labelled peptides for nuclear medicine

International Nuclear Information System (INIS)

2002-09-01

The general scope of this CRP focused on the optimization of syntheses, quality control, in vitro and in vivo evaluation of 18 F and 123 I radiopharmaceuticals based on peptides with known or anticipated clinical potential. Selective labelling procedures using prosthetic groups were applied to both fluorine and iodine. Studies included investigation on the fate of the label, stability in vivo, biodistribution and pharmacokinetic studies in rodents and in cell culture. With respect to 123 I, the work aimed at developing a simplified labelling kit using solid state systems. The first Research Co-ordination Meeting (RCM) that was held in August 1997 took up and decided on the criteria for selecting the peptides and agreed upon a set of recommended laboratory protocols for the CRP participants to follow and further optimize. Eight scientists from reputed laboratories from Argentina, Brazil, China, Germany, Greece, the Islamic Republic of Iran, Saudi Arabia and the United States of America participated in the CRP. Three RCMs were held where the participants presented their scientific results: August 1997 in Sao Paulo, Brazil, April 1999 in Athens, Greece, and November 2000 in Shanghai, People's Republic of China. Reports describing the research work of all participants are included herein. Each of the report has been indexed separately

Phagocytosis of gram-negative bacteria by a unique CD14-dependent mechanism.

Science.gov (United States)

Schiff, D E; Kline, L; Soldau, K; Lee, J D; Pugin, J; Tobias, P S; Ulevitch, R J

1997-12-01

THP-1-derived cell lines were stably transfected with constructs encoding glycophosphatidylinositol (GPI)-anchored or transmembrane forms of human CD14. CD14 expression was associated with enhanced phagocytosis of serum (heat-inactivated)-opsonized Escherichia coli (opEc). Both the GPI-anchored and transmembrane forms of CD14 supported phagocytosis of opEc equally well. Lipopolysaccharide-binding protein (LBP) played a role in CD14-dependent phagocytosis as evidenced by inhibition of CD14-dependent phagocytosis of opEc with anti-LBP monoclonal antibody (mAb) and by enhanced phagocytosis of E. coli opsonized with purified LBP. CD14-dependent phagocytosis was inhibited by a phosphatidylinositol (PI) 3-kinase inhibitor (wortmannin) and a protein tyrosine kinase inhibitor (tyrphostin 23) but not a protein kinase C inhibitor (bisindolyl-maleimide) or a divalent cation chelator (ethylenediaminetetraacetate). Anti-LBP mAb 18G4 and anti-CD14 mAb 18E12 were used to differentiate between the pathways involved in CD14-dependent phagocytosis and CD14-dependent cell activation. F(ab')2 fragments of 18G4, a mAb to LBP that does not block cell activation, inhibited ingestion of opEc by THP1-wtCD14 cells. 18E12 (an anti-CD14 mAb that does not block LPS binding to CD14 but does inhibit CD14-dependent cell activation) did not inhibit phagocytosis of LBP-opEc by THP1-wtCD14 cells. Furthermore, CD14-dependent phagocytosis was not inhibited by anti-CD18 (CR3 and CR4 beta-chain) or anti-Fcgamma receptor mAb.

Architecture, systems research and computational sciences

CERN Document Server

2012-01-01

The Winter 2012 (vol. 14 no. 1) issue of the Nexus Network Journal is dedicated to the theme “Architecture, Systems Research and Computational Sciences”. This is an outgrowth of the session by the same name which took place during the eighth international, interdisciplinary conference “Nexus 2010: Relationships between Architecture and Mathematics, held in Porto, Portugal, in June 2010. Today computer science is an integral part of even strictly historical investigations, such as those concerning the construction of vaults, where the computer is used to survey the existing building, analyse the data and draw the ideal solution. What the papers in this issue make especially evident is that information technology has had an impact at a much deeper level as well: architecture itself can now be considered as a manifestation of information and as a complex system. The issue is completed with other research papers, conference reports and book reviews.

Proceedings of the IDA Workshop on Formal Specification and Verification of Ada (Trade Name) (1st) Held in Alexandria, Virginia on 18-20 March 1985.

Science.gov (United States)

1985-12-01

on the third day. 5 ADA VERIFICATION WORKSHOP MARCH 18-20, 1985 LIST OF PARTICIPANTS Bernard Abrams ABRAMS@ADA20 Grumman Aerospace Corporation Mail...20301-3081 (202) 694-0211 Mark R. Cornwell CORNWELL @NRL-CSS Code 7590 Naval Research Lab Washington, D.C. 20375 (202) 767-3365 Jeff Facemire FACEMIRE...accompanied by descriptions of their purpose in English, to LUCKHAM@SAIL for annotation. - X-2 DISTRIBUTION LIST FOR M-146 Bernard Abrams ABRAMS@USC-ECLB

Pengaruh Curah Hujan Dan Hari Hujan Terhadap Produksi Kelapa Sawit Berumur 12,15,18 Tahun Di PTPN II Unit Sawit Seberang – Babalan Kecamatan Sawit Seberang Kabupaten Langkat

OpenAIRE

Depari, Cecilia Natalenta; Irsal, Irsal; Ginting, Jonis

2015-01-01

The climate factor is very influential to the growth and productivity of palm oil. Rainfall is animportant climatic element observed. Where the palm oil is a plant that requires large amounts ofwater than other crops. Purpose of this research was to determine the effect of rainfall and rain dayas well as the correlation of both on palm oil production in plants aged 12, 15 and 18 years. Thisresearch was held at PTPN II Unit Sawit Seberang–Babalan Sub-district Sawit Seberang DistrictLangkat Pro...

14 CFR 91.865 - Phased compliance for operators with base level.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Phased compliance for operators with base... Noise Limits § 91.865 Phased compliance for operators with base level. Except as provided in paragraph... maximum of: (1) After December 31, 1994, 75 percent of the base level held by the operator; (2) After...

Production of radionuclides by 14 MeV neutron generator

International Nuclear Information System (INIS)

Alfassi, Z.B.

1983-01-01

Due to the short half-lives of these nuclides they have to be produced in situ or at least not far from the place of use. The cost of 14 MeV neutron generators have been compared with the typical middle-sized cyclotrons and it was found that the capital costs are much lower in the case of neutron generators. This is the main reason for the availability of 14 MeV neutron generators in many scientific institutes compared to the scarcity of cyclotrons. Lately, the use of 14 MeV neutrons for cancer therapy was studied in several medical centers. A number of hospitals and cancer research centers have high intensity 14 MeV neutron generators for this purpose. The advantages of using short-lived in-house produced radionuclides suggest the use of the available 14 MeV neutron generators for biological studies and in medical diagnosis. 14 MeV neutron generators can be used to produce some of the medically useful radionuclides, such as /sup 18/F, /sup 80/Br, /sup 199m/Hg, and others. However, the amount required for medicine can only be prepared by the new high intensity neutron generators, used for neutron therapy and not by the smaller ones, commonly used in university laboratories (--10/sup 11/ n/sec). On the other hand, these relatively small neutron generators can be used for the preparation of radionuclides for biological studies. They facilitate the study of metabolism of elements for which radionuclides cannot be usually purchased due to short half-lives or the high price of the long-lived ones, such as /sup 34m/Cl, /sup 18/F, /sup 28,29/Al, /sup 27/Mg, and others. An example is the work done on the fate of Al and Mg in rats using /sup 28/Al and /sup 27/Mg./sup 13/

Flight Test Experience With an Electromechanical Actuator on the F-18 Systems Research Aircraft

Science.gov (United States)

Jensen, Stephen C.; Jenney, Gavin D.; Raymond, Bruce; Dawson, David

2000-01-01

Development of reliable power-by-wire actuation systems for both aeronautical and space applications has been sought recently to eliminate hydraulic systems from aircraft and spacecraft and thus improve safety, efficiency, reliability, and maintainability. The Electrically Powered Actuation Design (EPAD) program was a joint effort between the Air Force, Navy, and NASA to develop and fly a series of actuators validating power-by-wire actuation technology on a primary flight control surface of a tactical aircraft. To achieve this goal, each of the EPAD actuators was installed in place of the standard hydraulic actuator on the left aileron of the NASA F/A-18B Systems Research Aircraft (SRA) and flown throughout the SRA flight envelope. Numerous parameters were recorded, and overall actuator performance was compared with the performance of the standard hydraulic actuator on the opposite wing. This paper discusses the integration and testing of the EPAD electromechanical actuator (EMA) on the SRA. The architecture of the EMA system is discussed, as well as its integration with the F/A-18 Flight Control System. The flight test program is described, and actuator performance is shown to be very close to that of the standard hydraulic actuator it replaced. Lessons learned during this program are presented and discussed, as well as suggestions for future research.

Growth and profitability in small privately held biotech firms: preliminary findings.

Science.gov (United States)

Brännback, Malin; Carsrud, Alan; Renko, Maija; Ostermark, Ralf; Aaltonen, Jaana; Kiviluoto, Niklas

2009-06-01

This paper reports on preliminary findings on a study of the relationship of growth and profitability among small privately held Finnish Life Science firms. Previous research results concerning growth and profitability are mixed, ranging from strongly positive to a negative relationship. The conventional wisdom states that growth is a prerequisite for profitability. Our results suggest that the reverse is the case. A high profitability-low growth biotech firm is more probably to make the transition to high profitability-high growth than a firm that starts off with low profitability and high growth.

International Partnerships for Clinical Cancer Research

Science.gov (United States)

CGH co-sponsors the 2015 International Symposium on Cancer Clinical Trials and related meetings held in partnership with the Japanese National Cancer Center (JNCC) and Embassies of France, Korea, United Kingdom (UK), and United States (US) in Tokyo on May 14 - 15, 2015.

CCR presentations at AACR - 2018 | Center for Cancer Research

Science.gov (United States)

CCR presentations at AACR Several CCR scientists will present their research at the AACR Annual Meeting in Chicago, IL, between April 14-18, 2018. Selected oral presentations are listed below. A full list of abstracts can be found on the AACR website.

Attitudes of pregnant women towards personally controlled electronic, hospital-held, and patient-held medical record systems: a survey study.

Science.gov (United States)

Quinlivan, Julie A; Lyons, Sarah; Petersen, Rodney W

2014-09-01

On July 1, 2012 the Australian Government launched the personally controlled electronic health record (PCEHR). This article surveys obstetric patients about their medical record preferences and identifies barriers to adoption of the PCEHR. A survey study was conducted of antenatal patients attending a large Australian metropolitan hospital. Consecutive patients completed questionnaires during the launch phase of the PCEHR system. Quantitative and qualitative data were collected on demographics, computer access and familiarity, preference for medical record system, and perceived benefits and concerns. Of 528 women eligible to participate, 474 completed the survey (89.8%). Respondents had high levels of home access to a computer (90.5%) and the Internet (87.1%) and were familiar with using computers in daily life (median Likert scale of 9 out of 10). Despite this, respondents preferred hospital-held paper records, and only one-third preferred a PCEHR; the remainder preferred patient-held records. Compared with hospital-held paper records, respondents felt a PCEHR would reduce the risk of lost records (padvantages and disadvantages with the PCEHR, although the majority still prefer existing record systems. To increase uptake, confidentiality, privacy, and control concerns need to be addressed.

The Conception of Risk in Minority Young Adolescents Aged 12-14 Years

Science.gov (United States)

Leblanc, Raymond; Drolet, Marie; Ducharme, Daphne; Arcand, Isabelle; Head, Robert; Alphonse, Jean R.

2015-01-01

This study examines the conceptualization of risk behavior held by 26 Franco-Ontarian young adolescents (12-14 years of age) who participated in Lions Quest, a program specially designed to promote physical and mental health and to prevent drug and alcohol use. More specifically, it seeks to better understand the participating adolescents'…

Gen-2 Hand-Held Optical Imager towards Cancer Imaging: Reflectance and Transillumination Phantom Studies

Directory of Open Access Journals (Sweden)

Anuradha Godavarty

2012-02-01

Full Text Available Hand-held near-infrared (NIR optical imagers are developed by various researchers towards non-invasive clinical breast imaging. Unlike these existing imagers that can perform only reflectance imaging, a generation-2 (Gen-2 hand-held optical imager has been recently developed to perform both reflectance and transillumination imaging. The unique forked design of the hand-held probe head(s allows for reflectance imaging (as in ultrasound and transillumination or compressed imaging (as in X-ray mammography. Phantom studies were performed to demonstrate two-dimensional (2D target detection via reflectance and transillumination imaging at various target depths (1–5 cm deep and using simultaneous multiple point illumination approach. It was observed that 0.45 cc targets were detected up to 5 cm deep during transillumination, but limited to 2.5 cm deep during reflectance imaging. Additionally, implementing appropriate data post-processing techniques along with a polynomial fitting approach, to plot 2D surface contours of the detected signal, yields distinct target detectability and localization. The ability of the gen-2 imager to perform both reflectance and transillumination imaging allows its direct comparison to ultrasound and X-ray mammography results, respectively, in future clinical breast imaging studies.

Simulation model of the F/A-18 high angle-of-attack research vehicle utilized for the design of advanced control laws

Science.gov (United States)

Strickland, Mark E.; Bundick, W. Thomas; Messina, Michael D.; Hoffler, Keith D.; Carzoo, Susan W.; Yeager, Jessie C.; Beissner, Fred L., Jr.

1996-01-01

The 'f18harv' six degree-of-freedom nonlinear batch simulation used to support research in advanced control laws and flight dynamics issues as part of NASA's High Alpha Technology Program is described in this report. This simulation models an F/A-18 airplane modified to incorporate a multi-axis thrust-vectoring system for augmented pitch and yaw control power and actuated forebody strakes for enhanced aerodynamic yaw control power. The modified configuration is known as the High Alpha Research Vehicle (HARV). The 'f18harv' simulation was an outgrowth of the 'f18bas' simulation which modeled the basic F/A-18 with a preliminary version of a thrust-vectoring system designed for the HARV. The preliminary version consisted of two thrust-vectoring vanes per engine nozzle compared with the three vanes per engine actually employed on the F/A-18 HARV. The modeled flight envelope is extensive in that the aerodynamic database covers an angle-of-attack range of -10 degrees to +90 degrees, sideslip range of -20 degrees to +20 degrees, a Mach Number range between 0.0 and 2.0, and an altitude range between 0 and 60,000 feet.

Comparison of two single-breath-held 3-D acquisitions with multi-breath-held 2-D cine steady-state free precession MRI acquisition in children with single ventricles

Energy Technology Data Exchange (ETDEWEB)

Atweh, Lamya A.; Dodd, Nicholas A.; Krishnamurthy, Ramkumar; Chu, Zili D. [Texas Children' s Hospital, EB Singleton Department of Pediatric Radiology, Cardiovascular Imaging, Houston, TX (United States); Pednekar, Amol [Philips Healthcare, Houston, TX (United States); Krishnamurthy, Rajesh [Texas Children' s Hospital, EB Singleton Department of Pediatric Radiology, Cardiovascular Imaging, Houston, TX (United States); Baylor College of Medicine, Department of Radiology, Houston, TX (United States); Baylor College of Medicine, Department of Pediatrics, Houston, TX (United States)

2016-05-15

Breath-held two-dimensional balanced steady-state free precession cine acquisition (2-D breath-held SSFP), accelerated with parallel imaging, is the method of choice for evaluating ventricular function due to its superior blood-to-myocardial contrast, edge definition and high intrinsic signal-to-noise ratio throughout the cardiac cycle. The purpose of this study is to qualitatively and quantitatively compare the two different single-breath-hold 3-D cine SSFP acquisitions using 1) multidirectional sensitivity encoding (SENSE) acceleration factors (3-D multiple SENSE SSFP), and 2) k-t broad-use linear acceleration speed-up technique (3-D k-t SSFP) with the conventional 2-D breath-held SSFP in non-sedated asymptomatic volunteers and children with single ventricle congenital heart disease. Our prospective study was performed on 30 non-sedated subjects (9 healthy volunteers and 21 functional single ventricle patients), ages 12.5 +/- 2.8 years. Two-dimensional breath-held SSFP with SENSE acceleration factor of 2, eight-fold accelerated 3-D k-t SSFP, and 3-D multiple SENSE SSFP with total parallel imaging factor of 4 were performed to evaluate ventricular volumes and mass in the short-axis orientation. Image quality scores (blood myocardial contrast, edge definition and interslice alignment) and volumetric analysis (end systolic volume, end diastolic volume and ejection fraction) were performed on the data sets by experienced users. Paired t-test was performed to compare each of the 3-D k-t SSFP and 3-D multiple SENSE SSFP clinical scores against 2-D breath-held SSFP. Bland-Altman analysis was performed on left ventricle (LV) and single ventricle volumetry. Interobserver and intraobserver variability in volumetric measurements were determined using intraclass coefficients. The clinical scores were highest for the 2-D breath-held SSFP images. Between the two 3-D sequences, 3-D multiple SENSE SSFP performed better than 3-D k-t SSFP. Bland-Altman analysis for volumes

Acquisition Research: Creating Synergy for Informed Change. Proceedings of the Annual Acquisition Research Symposium (5th) Held in Monterey, California on 14-15 May 2008. Volume 1

Science.gov (United States)

2008-04-23

replacing its aging tanker fleet. Boeing has had a history of tardiness and delays, which reduces its argument that it is a reliable supplier. For...Author: Romulo B. Magnaye received his BS in Mining Engineering and MBA from the University of the Philippines and a postgraduate research Diploma in

A pilot analytic study of a research-level, lower-cost human papillomavirus 16, 18, and 45 test

OpenAIRE

Yang, Hannah P.; Walmer, David K.; Merisier, Delson; Gage, Julia C.; Bell, Laura; Rangwala, Sameera; Shrestha, Niwashin; Kobayashi, Lori; Eder, Paul S.; Castle, Philip E.

2011-01-01

The analytic performance of a low-cost, research-stage DNA test for the most carcinogenic human papillomavirus (HPV) genotypes (HPV16, HPV18, and HPV45) in aggregate was evaluated among carcinogenic HPV-positive women, which might be used to decide who needs immediate colposcopy in low-resource settings (“triage test”). We found that HPV16/18/45 test agreed well with two DNA tests, a GP5+/6+ genotyping assay (Kappa = 0.77) and a quantitative PCR assay (at a cutpoint of 5000 viral copies) (Kap...

Assessment of the risk of salmonellosis from internally contaminated shell eggs following initial storage at 18 °C (65 °F), compared with 7 °C (45 °F).

Science.gov (United States)

Pouillot, R; Hoelzer, K; Ramirez, G A; deGraft-Hanson, J; Dennis, S B

2014-10-01

In the U.S., chicken-breeder farms that supply hatcheries typically store and transport eggs intended for broiler production at a temperature of 18.3 °C (65 °F). However, in case of surplus, some of these eggs may be diverted to human consumption. According to the U.S. Food and Drug Administration's 'Egg Safety Final Rule,' shell eggs intended for human consumption are required to be held or transported at or below 7.2 °C (45 °F) ambient temperature beginning 36 h after time of lay. We adapted a risk assessment model developed by the U.S. Department of Agriculture's Food Safety Inspection Service, to quantify human exposure to Salmonella Enteritidis and the risk of human salmonellosis if eggs are held and transported at 18.3 °C for up to 5.5 days after time of lay, as has been observed when hatchery eggs are diverted to human consumption, rather than held and transported at 7.2 °C within 36 h after time of lay. Storage at 18.3 °C leads to considerable bacterial growth in internally contaminated eggs. The model predicted that more than 10% of internally contaminated eggs would remain contaminated after in-shell pasteurization resulting in a 5-log10 reduction, and that some bacteria would survive after home-cooking. The model predicted that, alternatively, eggs stored at 7.2 °C after lay would have limited bacterial growth prior to pasteurization, and Salmonella would be very unlikely to be present after pasteurization. The predicted risk of salmonellosis from the consumption of eggs held and transported at 18.3 °C and subsequently diverted to human consumption is 25 times higher than the risk when eggs are held and transported at 7.2 °C. Published by Elsevier Ltd.

Innovative Tuberculosis Symposium held during Cuba Salud 2015.

Science.gov (United States)

Chapman, Helena J; Armas Pérez, Luisa

2016-12-01

The fourth Tuberculosis (TB) Symposium, held during the Cuba Salud 2015 International Convention, highlighted advancements in research on TB and Mycobacterium tuberculosis (Mtb) by interdisciplinary teams from academic and federal institutions in Cuba, Colombia, Mexico, and the Dominican Republic. Delegates focused on the targets presented in the World Health Organization End TB Strategy for 2016-2035 and elaborated on four primary themes: 1) attention to vulnerable populations such as immunocompromised individuals, health care workers, and residents of long-term institutions such as prisons and nursing homes; 2) identification of active and latent TB cases through contact investigations; 3) spread and control of drug-resistant Mtb strains; and 4) advancements in the development of novel vaccines or "booster" immunizations. This international TB forum served as a platform for experts in diverse disciplines in these Latin American countries to discuss challenges faced by TB research and control programs, proposing novel research initiatives and promoting collaborative teamwork strategies for TB elimination. In solidarity, collaborative efforts in TB control require identification of symptomatic individuals, rapid diagnostic testing for TB, drug susceptibility assays on Mtb strains, and management that provide universal and gratuitous access to directly observed short-course therapy. Copyright © 2016 Elsevier Ltd. All rights reserved.

International Conference in Memory of Professor Kôsaku Yosida held at RIMS

CERN Document Server

1993-01-01

In these proceedings of the international conference held in Kyoto in memoryof the late Professor K saku Yosida, twenty six invited speakers display in their many facets of functional analysis and its applications in the research tradition of Yosida's school. Many of the topics are related tolinear and non-linear partial differential equations, including the Schr|dinger equations, the Navier-Stokes equations and quasilinear hyperbolic equations. Several of the papers are survey articles, the others are original (unpublished) and refereed research articles. Also included is a full listing of the publications of K. Yosida. Recommendedto students and research workers looking for a bird's-eye view of current research activity in functional analysis and its applications. FROM THE CONTENTS: K. Ito: Semigroups in probability theory.- T. Kato: Abstract evolution equations, linear and quasilinear, revisited.- J.L. Lions: Remarkson systems with incompletely given initial data and incompletely given part of the boundary...

Double-hit lymphoma demonstrating t(6;14;18)(p25;q32;q21), suggesting two independent dual-hit translocations, MYC/BCL-2 and IRF4/BCL-2.

Science.gov (United States)

Tabata, Rie; Yasumizu, Ryoji; Tabata, Chiharu; Kojima, Masaru

2013-01-01

Here, we report a rare case of double-hit lymphoma, demonstrating t(6;14;18)(p25;q32;q21), suggesting two independent dual-translocations, c-MYC/BCL-2 and IRF4/BCL-2. The present case had a rare abnormal chromosome, t(6;14;18)(p25;q32;q21), independently, in addition to known dual-hit chromosomal abnormalities, t(14;18)(q32;q21) and t(8;22)(q24;q11.2). Lymph node was characterized by a follicular and diffuse growth pattern with variously sized neoplastic follicles. The intrafollicular area was composed of centrocytes with a few centroblasts and the interfollicular area was occupied by uniformly spread medium- to large-sized lymphocytes. CD23 immunostaining demonstrated a disrupted follicular dendritic cell meshwork. The intrafollicular tumor cells had a germinal center phenotype with the expression of surface IgM, CD10, Bcl-2, Bcl-6, and MUM1/IRF4. However, the interfollicular larger cells showed plasmacytic differentiation with diminished CD20, Bcl-2, Bcl-6, and positive intracytoplasmic IgM, and co-expression of MUM1/IRF4 and CD138 with increased Ki-67-positive cells (> 90%). MUM1/IRF4 has been found to induce c-MYC expression, and in turn, MYC transactivates MUM1/IRF4, creating a positive autoregulatory feedback loop. On the other hand, MUM1/IRF4 functions as a tumor suppressor in c-MYC-induced B-cell leukemia. The present rare case arouses interest in view of the possible "dual" activation of both c-MYC and MUM1/IRF4 through two independent dual-translocations, c-MYC/BCL-2 and IRF4/BCL-2.

Si effects on radiation induced segregation in high purity Fe-18Cr-14Ni alloys irradiated by Ni ions

International Nuclear Information System (INIS)

Ohta, Joji; Kako, Kenji; Mayuzumi, Masami; Kusanagi, Hideo; Suzuki, Takayoshi

1999-01-01

To illustrate the effects of the element Si on radiation induced segregation, which causes irradiation assisted stress corrosion cracking (IASCC), we investigated grain boundary chemistry of high purity Fe-18Cr-14Ni-Si alloys irradiated by Ni ions using FE-TEM. The addition of Si up to 1% does not affect the Cr depletion at grain boundaries, while it slightly enhances the depletion of Fe and the segregation of Ni and Si. The addition of 2% Si causes the depletion of Cr and Fe and the segregation of Ni and Si at grain boundaries. Thus, the Si content should be as low as possible. In order to reduce the depletion of Cr at grain boundaries, which is one of the major causes of IASCC, Si content should be less than 1%. (author)

7 CFR 1215.18 - Secretary.

Science.gov (United States)

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Secretary. 1215.18 Section 1215.18 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION Popcorn Promotion, Research, and Consumer Information Order Definitions § 1215.18...

Copyright | IDRC - International Development Research Centre

International Development Research Centre (IDRC) Digital Library (Canada)

Where copyright is held by IDRC Unless otherwise stated, the copyright to material on this website is held by the International Development Research Centre (IDRC). IDRC permits reading, downloading, copying, redistributing, printing, linking and searching, for non-commercial or academic purposes, of any of its content, ...

NATO Advanced Research Workshop on Frontiers of High-Pressure Research

CERN Document Server

Etters, Richard

1991-01-01

The role of high pressure experiments in the discovery of supercon­ ducting materials with a T. above liquid nitrogen temperature has demon­ strated the importance of such experiments. The same role holds true in the tailoring of materials for optoelectronic devices. In addition, much progress has been made recently in the search for metallic hydro­ gen, and the application of high pressure in polymer research has brought forth interesting results. These facts together with the suc­ cess of previous small size meetings (such as the "First International Conference on the Physics of Solids at High Pressure", held in 1965 in Tucson, Arizona, U. S. A. ; "High Pressure and Low Temperature Physics", held in 1977 in Cleveland, Ohio, U. S. A. ; and "Physics of Solids Under High Pressure", held in 1981 in bad Honnef, Germany), motivated us to organize a workshop with emphasis on the newest results and trends in these fields of high pressure research. Furthermore, it was intended to mix experienced and young scien�...

18 MArch 2008 - Director, Basic and Generic Research Division, Research Promotion Bureau, Japanese Ministry of Education, Culture, Sports, Science and Technology Prof.Ohtake visiting ATLAS cavern with Spokesperson P. Jenni.

CERN Multimedia

Maximilien Brice

2008-01-01

18 MArch 2008 - Director, Basic and Generic Research Division, Research Promotion Bureau, Japanese Ministry of Education, Culture, Sports, Science and Technology Prof.Ohtake visiting ATLAS cavern with Spokesperson P. Jenni.

Survey and research on precision polymerization polymeric materials; Seimitsu jugo kobunshi zairyo ni kansuru chosa kenkyu

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-03-01

Survey and research on the precision control of primary structure of polymeric materials and the precision evaluation technology have been conducted to develop advanced polymeric materials. It is proposed that the three basic processes of polymer synthesis, i.e., addition, condensation, and biomimesis, in forming the precision polymerization skeleton are to be covered through a centralized joint research effort with participation of industry, academia, and the government institute and under the leadership of researchers from academic institutions as the team leaders. For the study of technology trends, international conferences held in UK, Germany, and Hawaii are introduced, and domestic meetings, i.e., Annual Polymer Congress and Polymer Conference, are summarized. In addition, Precision Polymerization Forum and International Workshop on Precision Polymerization were held. The basic studies include a quantum-chemical elucidation of the elementary process in polymerization reaction, time-resolved analysis of polymerization process and polymer properties, synthesis of polymers with controlled microstructures by coordination polymerization using metal complexes, synthesis of polymer with controlled microstructures by precision polycondensation, molecular recognition in catalyst-reaction site, and synthesis of imprinting polymers. 246 refs., 117 figs., 14 tabs.

20 CFR 416.1208 - How funds held in financial institution accounts are counted.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false How funds held in financial institution accounts are counted. 416.1208 Section 416.1208 Employees' Benefits SOCIAL SECURITY ADMINISTRATION... held in financial institution accounts are counted. (a) General. Funds held in a financial institution...

The FY1997 meeting for information exchange of geoscience research. Collection of literature

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-09-01

The Tono Geoscience Center of PNC has been conducting research programs aiming at underground disposal of radioactive wastes. This document is the collection of summary papers presented to the meeting which was held at Toki, Gifu Prefecture on July 17 - 18, 1997. Total of 33 papers are given under two main themes: (1) research on long-term stability of geologic environment and (2) research on characteristics of geologic environment. The second theme is further divided into the four sub-themes: (a) investigation in the Tono Mine, (b) research of broad underground water flow, (c) in-situ test at Kamaishi and (d) development of survey techniques and equipment. Seven papers are contributed to the first theme and 21 papers to the second: five papers to (a), six to (b), seven to (c) and six to (d), including three of the poster session. (H. Yokoo)

Report ETSI M2M-14bis JTC March 2011 meeting

NARCIS (Netherlands)

Keesmaat, N.W.

2011-01-01

The ETSI Technical Committee (TC) M2M focuses on the development of a generic M2M architecture and underlying protocols suitable for a wide range of M2M environments. Whereas in the past effort has been put in the development of several use cases, the focus of this M2M 14bis meeting – held in Sophia

Attentionally splitting the mass distribution of hand-held rods.

Science.gov (United States)

Burton, G; Turvey, M T

1991-08-01

Two experiments on the length-perception capabilities of effortful or dynamic touch differed only in terms of what the subject intended to perceive, while experimental conditions and apparatus were held constant. In each trial, a visually occluded rod was held as still as possible by the subject at an intermediate position. For two thirds of the trials, a weight was attached to the rod above or below the hand. In Experiment 1, in which the subject's task was to perceive the distance reachable with the portion of the rod forward of the hand, perceived extent was a function of the first moment of the mass distribution associated with the forward portion of the rod, and indifferent to the first moment of the entire rod. In Experiment 2, in which the task was to perceive the distance reachable with the entire rod if it was held at an end, the pattern of results was reversed. These results indicate the capability of selective sensitivity to different aspects of a hand-held object's mass distribution, without the possibility of differential exploration specific to these two tasks. Results are discussed in relation to possible roles of differential information, intention, and self-organization in the explanations of selective perceptual abilities.

Influence of dietary fat on metabolism of (14-14C)erucic acid in the perfused rat liver. Distribution of metabolites in lipid classes

International Nuclear Information System (INIS)

Holmer, G.; Ronneberg, R.

1986-01-01

Two groups of rats were fed diets containing 20% by weight of either partially hydrogenated marine oil supplemented with sunflower seed oil (PHMO) or palm oil (PO) for 8 wk. Using a liver perfusion system, the effect of dietary long chain monoenoic fatty acids on the uptake and metabolism of [14- 14 C]erucic acid was studied. The perfusion times were 15 and 60 min, respectively. The two groups showed equal ability for erucic acid uptake in the liver but differed in the channeling of the fatty acids into various metabolic pathways. A higher metabolic turnover of 22:1 in the PHMO livers relative to the PO livers was demonstrated by an increased recovery of total [ 14 C]labeling in the triglyceride (TG) and phospholipid (PL) fractions, already evident after 15 min of perfusion. The chain-shortening capacity was highest in the PHMO group, reflected by a higher [ 14 C]18:1 incorporation in both TG and PL, and increasing from 15 to 60 min of perfusion. The amount of [ 14 C]18:1 found in PL and TG after 60 min of perfusion of livers from rats fed PO corresponded to that shown for the PHMO group after 15 min. The PL demonstrated a discrimination against 22:1 compared to TG, and, when available, 18:1 was highly preferred for PL-synthesis. The total fatty acid distribution in the TG, as determined by gas liquid chromatography (GLC), reflected the composition of the dietary fats. In the total liver PL, 22:1 and 20:1 were present in negligible amounts, although the PHMO diet contained 12-13% of both 22:1 and 20:1. In the free fatty acid fraction (FFA), the major part of the radioactivity (approximately 80%) was [14- 14 C]erucic acid, and only small amounts of [ 14 C]18:1 (less than 2%) were present, even after 60 min of perfusion. The shortened-chain 18:1 was readily removed from the FFA pool and preferentially used for lipid esterification

Summary of the 2016 Alcohol and Immunology Research Interest Group (AIRIG) meeting.

Science.gov (United States)

Boule, Lisbeth A; Ju, Cynthia; Agudelo, Marisela; Parira, Tiyash; Cannon, Abigail; Davis, Booker; Eby, Jonathan; Cresci, Gail; Samuelson, Derrick R; Shukla, Pradeep; Alrefai, Waddah A; Sureshchandra, Suhas; Pandey, Subhash C; Schnabl, Bernd; Curtis, Brenda J; Wyatt, Todd A; Choudhry, Mashkoor A; Kovacs, Elizabeth J

2018-02-01

On November 18, 2016 the 21st annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held at the Center for Translational Research and Education at Loyola University Chicago's Health Sciences Campus in Maywood, IL. The 2016 meeting focused broadly on alcohol and inflammation, epigenetics, and the microbiome. The four plenary sessions of the meeting were Alcohol, Inflammation, and Immunity; Alcohol and Epigenetics; Alcohol, Transcriptional Regulation, and Epigenetics; and Alcohol, Intestinal Mucosa, and the Gut Microbiome. Presentations in all sessions of the meeting explored putative underlying causes for chronic diseases and mortality associated with alcohol consumption, shedding light on future work and potential therapeutic targets to alleviate the negative effects of alcohol misuse. Copyright © 2017 Elsevier Inc. All rights reserved.

Report of the evaluation by the Ad Hoc Review Committee on Nuclear Safety Research. Result evaluation in fiscal year 2000

International Nuclear Information System (INIS)

2001-06-01

The Research Evaluation Committee, which consisted of 14 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Nuclear Safety Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the R and D accomplishments achieved for five years from Fiscal Year 1995 to Fiscal Year 1999 at Department of Reactor Safety Research, Department of Fuel Cycle Safety Research, Department of Environmental Safety Research and Department of Safety Research Technical Support in Tokai Research Establishment at JAERI. The Ad Hoc Review Committee consisted of 11 specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from December 2000 to February 2001. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on December 11, 2000, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on March 16, 2001. This report describes the result of the evaluation by the Ad Hoc Review Committee on Nuclear Safety Research. (author)

Report of the evaluation by the Ad Hoc Review Committee on Materials Science Research. Ex-post evaluation in fiscal year 2003

International Nuclear Information System (INIS)

2004-06-01

The Research Evaluation Committee, which consisted of 13 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Materials Science Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the adequacy of the R and D results achieved for five years until Fiscal Year 2002 at Department of Materials Science in Tokai Research Establishment of JAERI. The Ad Hoc Review Committee consisted of eight specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from October 2003 to February 2004. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on November 14, 2003, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on March 8, 2004. This report describes the result of the evaluation by the Ad Hoc Review Committee on Materials Science Research. (author)

14 CFR 21.73 - Eligibility.

Science.gov (United States)

2010-01-01

... Class II provisional type certificates, for amendments to provisional type certificates held by him, and for provisional amendments to type certificates held by him. (b) Any manufacturer of aircraft... provisional type certificates held by him, and for provisional amendments to type certificates held by him. (c...

20 CFR 418.3420 - How are funds held in financial institution accounts counted?

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2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false How are funds held in financial institution... SUBSIDIES Medicare Part D Subsidies Resources § 418.3420 How are funds held in financial institution accounts counted? (a) Owner of the account. Funds held in a financial institution account (including...

18th Meeting of the IFRC Subcommittee on Atomic and Molecular Data for Fusion. Summary Report of an IAEA Technical Meeting

International Nuclear Information System (INIS)

Braams, B.J.

2013-12-01

The 18th meeting of the Subcommittee on Atomic and Molecular Data of the International Fusion Research Council (IFRC) was held on 26-27 April 2012 at IAEA Headquarters in Vienna, Austria. Activities of the Atomic and Molecular Data Unit for the period 2010-2012 were reviewed and recommendations were made for continuig activitiees in 2012-2013 and for new projects in the 2014-2015 budget cycle. The proceedings, conclusions and recommendations of the Subcommittee meeting are briefly described in this report. Specific recommendations of the Subcommittee from this meeting, as well as the report on the activities of the IAEA Atomic and Molecular Data Unit for the period May 2010 - April 2012, are also included. (author)

14th International Workshop on Slow Positron Beam Techniques and Applications

International Nuclear Information System (INIS)

2017-01-01

These proceedings arose from the 14th International Workshop on Slow Positron Beam Techniques (SLOPOS14), which was held at Kunibiki Messe, Matsue, Shimane prefecture, Japan, from the 22nd—27th May 2016. Meetings in the SLOPOS series are held every three years. The SLOPOS workshop series has traditionally been devoted to investigations on the production of positron and positronium beams, their fundamental physics and chemistry, and their applications to materials such as metals, semiconductors and soft matter. During the workshop numerous applications using positron and positronium beams were also presented, clearly demonstrating the usefulness of such beams to the determination of surface structure, defect characterization as well as to fundamental scientific studies. For SLOPOS14 the main subjects of the workshop included the following: • Positron transport and beam technology • Pulsed positron beams and positron traps • Defect profiling in bulk and layered structures • Nano structures, porous materials and thin films • Surface and interface analysis • Positronium formation, emission and beams • Positron and positronium interactions with atoms and molecules • Many positrons and anti-hydrogen • Improvement of experimental techniques 106 delegates from 14 countries participated in the SLOPOS14, including 31 student delegates, which was a most encouraging sign for the future. The scientific program comprised 5 plenary talks, 22 invited talks, 32 contributed talks and 46 posters presented during two poster sessions. Student prizes were awarded for the best presented scientific contributions by 4 students from University of College London, Universität der Bundeswehr München and The University of Tokyo. On a sad note, delegates paid tribute to the contributions of our recently deceased colleagues, Prof. A. Seeger, Prof. R.N. West, Prof. T.C. Griffith, and Prof. Z. Tang. Memorial talks were given and a one minute silence was observed before the

7 CFR 1216.14 - Market.

Science.gov (United States)

2010-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PEANUT PROMOTION, RESEARCH, AND INFORMATION ORDER Peanut Promotion, Research, and Information Order Definitions § 1216.14 Market. Market means... 7 Agriculture 10 2010-01-01 2010-01-01 false Market. 1216.14 Section 1216.14 Agriculture...

EUROTHERM Seminar No. 18

CERN Document Server

Heggs, Peter; Butterworth, David

1992-01-01

The Eurotherm Committee was created in 1986 from member countries of the European Community. It has the purpose of organising and coordinating scientific events such as seminars and conferences in the thermal sciences. The series of Eurotherm Seminars established by the Committee has become a popular forum for high-level scientific and technical interchange of ideas in a wide range of specialist topics. While the presentation and publication of papers at the Seminars are encouraged, the primary aim is to stimulate discussion and liaison between specialist groups. The present Chairman of Eurotherm is Professor C.J. Hoogendoorn of the Technical University, Delft (Fax [NL] 15, 783251). Information on Mure Seminars is available from the Secretary, Keith Cornwell, Heriot-Watt University, Edinburgh (Fax [UK] 31, 451, 3129). This particular Seminar No. 18 on the Design and Operation of Heat Exchangers was the first one on this topic and was held at the Universitat der Bundeswehr Hamburg (University of the Federal Ar...

14(R,S)-[18F]Fluoro-6-thia-heptadecanoic acid as a tracer of free fatty acid uptake and oxidation in myocardium and skeletal muscle

International Nuclear Information System (INIS)

Takala, Teemu O.; Nuutila, Pirjo; Pulkki, Kari; Oikonen, Vesa; Groenroos, Tove; Bergman, Joergen; Forsback, Sarita; Knuuti, Juhani; Savunen, Timo; Vaehaesilta, Tommi; Luotolahti, Matti; Kallajoki, Markku

2002-01-01

14(R,S)-[ 18 F]Fluoro-6-thia-heptadecanoic acid ([ 18 F]FTHA) is a long-chain fatty acid substrate for fatty acid metabolism. [ 18 F]FTHA has been used to study fatty acid metabolism in human heart and skeletal muscle. It has been suggested that the rate of radioactivity accumulation in the myocardium reflects the beta-oxidation rate of free fatty acids (FFAs). However, the net accumulation of FFAs in tissue always represents the sum of FFA oxidation and incorporation into triglycerides. The fraction of [ 18 F]FTHA entering directly into mitochondria for oxidation has not been previously measured. Eight anaesthetized pigs were studied with [ 18 F]FTHA and positron emission tomography (PET). Immediately after each PET experiment, tissue samples from myocardium and skeletal muscle were taken for the isolation of mitochondria and measurements of radioactivity accumulation, and for intracellular [ 18 F]FTHA metabolite analysis. Fractional [ 18 F]FTHA uptake rates were calculated both by graphical analysis of PET data and by measuring 18 F in the tissue samples. Fractional [ 18 F]FTHA uptake rates based on the analysis of tissue samples were 0.56±0.17 ml g -1 min -1 and 0.037±0.007 ml g -1 min -1 for myocardium and skeletal muscle (mean ± SD), respectively. The myocardial results obtained from the PET data (0.50±0.11 ml g -1 min -1 ) were similar to the values obtained from the tissue samples (r=0.94, P=0.002). We also found that 89%±23% (mean±SD, n=7) of the 18 F entered mitochondria in myocardium, as compared with only 36%±15% (mean±SD, n=7) in skeletal muscle. Intracellular [ 18 F]FTHA metabolite analysis showed that a major part of [ 18 F]FTHA is metabolized in the mitochondria in the heart. Our data suggest that 89% of [ 18 F]FTHA taken up by the heart enters mitochondria. This supports the hypothesis that [ 18 F]FTHA traces FFA beta-oxidation in the heart. In contrast to this, only 36% of [ 18 F]FTHA accumulated in skeletal muscle appears to directly enter

Earthworms as Invasive Species in Latin America — the 2nd Latin American Meeting on Oligochaeta (Earthworm) Ecology and Taxonomy

Science.gov (United States)

Grizelle Gonzalez

2006-01-01

This special issue is based on scientific contributions presented at the 2nd Latin American Symposium of Earthworm Ecology and Taxonomy (ELAETAO, for its Spanish acronym) held in San Juan, Puerto Rico November 14-18, 2005. The first of these symposia was organized by George G. Brown and Klaus D. Sautter and held at Londrina, Brazil from December 1-3, 2003.The objective...

Abstract EPSM-ABEC 2011 Conference

International Nuclear Information System (INIS)

2011-01-01

The Engineering and Physical Science in Medicine and The Australian Biomedical Engineering College Conference, was held at Darwin, Australia from 14 to 18 August, 2011, Darwin Convention Centre, Northern Territory, Australia.

Fasting, justification, and self-righteousness in Luke 18:9–14: A social-scientific interpretation as response to Friedrichson

Directory of Open Access Journals (Sweden)

Steven H. Mathews

2013-09-01

Full Text Available This article provides a social-scientific interpretation of the role of fasting in Jesus’ parable of the Pharisee and the tax collector in Luke 18:9–14. Specifically, the article considers such social realia as honour and shame, collectivism, and purity in the interpretation of the text. The textual and social contexts of the text are considered. It is contended that in the parable Jesus presents a caricature of both the Pharisee and the tax collector to make a larger point, in which fasting is not a major consideration. The article also evaluates Friedrichson’s interpretation of this text, which depicts the Pharisee as fasting vicariously, resulting in the justification of the tax collector. Finally, the significance of this text in a holistic theology of fasting in the New Testament is considered.

Isotope and geochemical techniques applied to geothermal investigations. Proceedings of the final research co-ordination meeting held in Dumaguete City, Philippines, 12-15 October 1993

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-02-01

In the last ten years, geothermal energy has emerged as an alternative source of energy for electrical and non-electrical uses. In some of these countries geothermal energy contributed up to 40% of the national power requirement. In others, it is being widely used in agriculture, aquaculture, air conditioning, kiln and fruit drying, pulp and paper industry, greenhouses and food processing. The Co-ordinated Research Programme (CRP) on the Application of Isotope and Geochemical Techniques to Geothermal Exploration in the Middle East, Asia, the Pacific and Africa aimed at integrating isotope techniques with traditional geochemical and hydrological methods in understanding the characteristics of geothermal systems. It involved isotopic and chemical surveys of hot to cold springs, wells and rivers in exploration areas as well as in exploited reservoirs where problems such as return of injected wastewaters are experienced. This publication is a compilation of the scientific papers presented at the final Research Co-ordination Meeting, held in Dumaguete City, Philippines, from 12 to 15 October 1993. Refs, figs and tabs.

Food Irradiation Newsletter. V. 14, no. 1

International Nuclear Information System (INIS)

1990-05-01

This issue reports activities of the ICGFI, especially the excerpts of its 6th Annual Meeting held in Vienna in October 1989. The Action Plan of the ICGFI Inter-American Meeting on Harmonization of Regulations Related to Trade in Irradiated Foods, held in Orlando, Florida last year, is also included. The conclusions of the three co-ordinated research programme organized by the Food Preservation Section during 1989 are reported and a survey of market testings of irradiated food carried out in different countries in the past 5 years is described. A supplement gives an up-dated list of clearance of irradiated foods based on information received from various countries. Refs, 1 fig., tabs

5 CFR 1315.18 - Inquiries.

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2010-01-01

... Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET OMB DIRECTIVES PROMPT PAYMENT § 1315.18 Inquiries. (a..., Financial Management Service (FMS), Cash Management Policy and Planning Division, 401 14th Street, SW... Management Service (FMS) at 1-800-266-9667. This information is also available at the FMS Prompt Payment Web...

47 CFR 32.3200 - Accumulated depreciation-held for future telecommunications use.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Accumulated depreciation-held for future... Balance Sheet Accounts § 32.3200 Accumulated depreciation—held for future telecommunications use. (a) This account shall include the accumulated depreciation associated with the investment contained in Account...

Electrical conductivity, differential scanning calorimetry, X-ray diffraction, and 7Li nuclear magnetic resonance studies of n-CxH(2x+1)OSO3Li (x = 12, 14, 16, 18, and 20)

International Nuclear Information System (INIS)

Hirakawa, Satoru; Morimoto, Yoshiaki; Honda, Hisashi

2015-01-01

Electrical conductivity (σ), differential scanning calorimetry (DSC), and X-ray diffraction (XRD) measurements of n-C x H (2x+1) OSO 3 Li (x= 12, 14, 16, 18, and 20) crystals were performed as a function of temperature. In addition, σ, DSC, and XRD observations of n-C x H (2x+1) OSO 3 Na and n-C x H (2x+1) OSO 3 K (x= 12, 14, 16, 18, and 20) crystals were carried out for comparison. DSC results of the salts revealed several solid-solid phase transitions with large entropy changes (ΔS). For n-C 18 H 37 OSO 3 Li and n-C 20 H 41 OSO 3 Li salts, each melting point produced a small ΔS mp value compared with the total entropy change in the solid phases (ΔS tr1 +ΔS tr2 ). Additionally, Li + ion diffusion was detected in the highest temperature solid phases. For K salts, larger σ values were detected for potassium alkylsulfates compared with those reported for alkyl carboxylate. 7 Li NMR spectra of n-C 18 H 37 OSO 3 Li crystals recorded in the low-temperature phase showed large asymmetry parameters, suggesting the Li + ions are localized at asymmetric sites in the crystals

Contributions of the German Research Center for Geosciences (GFZ) to the EPOS (European Plate Observing System) Implementation Phase 2015-18

Science.gov (United States)

Hoffmann, T. L.; Lauterjung, J.

2017-12-01

The European Plate Observing System project is currently approaching the end of year two of its four-year Implementation Phase 2015-18 (EPOS-IP). Under the Horizon 2020 Programme INFRADEV-3, the EPOS cyberinfrastructure is being established as an ERIC (European Research Infrastructure Consortium) and encompasses the implementation of both the EPOS Integrated Core Services (ICS) for solid Earth Science and a multitude of EPOS Thematic Core Services (TCS). During year two, a basic set of ICS and TCS services was developed and implemented, so that in October 2017 the validation phase (year 3) of EPOS is ready to be launched. Up to now, various TCS-Elements have integrated different Service Providers (SD) that are delivering Data, Data Products, Services and Software (DDSS) to their specific scientific community. As one of the 29 awardees of the EC grant, the German Research Center for Geosciences (GFZ) plays an important role in the implementation of EPOS and its Thematic and Integrated Core Services. The presented poster will give an overview of GFZ's participation in the work of nine technical EPOS Work Packages (WP7 ICS Development, WP8 Seismology, WP11 Volcano Observations, WP12 Satellite Data, WP13 Geomagnetic Observations, WP14 Anthropogenic Hazards, WP15 Geological Information and Modelling, WP16 Multi-Scale Laboratories and WP17 Geo Energy Test Beds) as well as in four administrative EPOS Work Packages (WP2 Communication, WP3 Harmonization, WP4 Legal & Governance, and WP5 Financial).

18F-NaF PET/CT for the evaluation of temporomandibular joint disorder.

Science.gov (United States)

Suh, M S; Park, S H; Kim, Y-K; Yun, P-Y; Lee, W W

2018-04-01

To investigate the usefulness of a quantitative parameter (maximum standardised uptake value [SUVmax]) of 18 F-sodium fluoride (NaF) positron-emission tomography (PET)/computed tomography (CT) for the evaluation of temporomandibular joint (TMJ) disorder (TMD). Seventy-six TMD patients (male: female=14:62, age=40.3±17.1 years, bilateral: unilateral=40:36) with 152 TMJs were enrolled. The 18 F-NaF PET/CT parameter (SUVmax) was compared with the presence of TMJ arthralgia (arthralgic=86, non-arthralgic=66) and clinical subtypes based on the Research Diagnostic Criteria for TMD Axis I (TMD osteoarthritis=49, non-TMD osteoarthritis=67, and asymptomatic TMJ=36). Splint therapy was applied to 48 patients for 6 months without considering 18 F-NaF PET/CT findings. Post-splint therapy 18 F-NaF PET/CT was performed in 32 patients and clinical responses to the therapy were classified into improvement (n=33), no change (n=10), or aggravation (n=7) for 50 TMJs excluding asymptomatic TMJs (n=14). SUVmax was significantly greater in arthralgic TMJs than in non-arthralgic TMJs (6.62±3.56 versus 4.32±1.53, pchange in SUVmax was observed in improved (from 6.16±2.68 to 6.09±2.60, p=0.4915) and unchanged (from 6.46±4.19 to 6.77±4.32, p=0.3223) TMJs. 18 F-NaF PET/CT is a useful imaging tool for TMD evaluation because SUVmax showed a fair diagnostic performance for arthralgic TMJ and TMD osteoarthritis, and a correlation with the therapeutic response. Copyright © 2017 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

Preliminary study on the evaluation of Langerhans cell histiocytosis using F-18-fluoro-deoxy-glucose PET/CT

Institute of Scientific and Technical Information of China (English)

Zhou Wenlan; Wu Hubing; Han Yanjiang; Wang Shaobo; Dong Ye; Wang Quanshi

2014-01-01

Background Limited number of studies have been reported regarding the utilization of F-18-fluoro-deoxy-glucose (F-18-FDG) positron emission tomography/computed tomography (F-18-FDG PET/CT) in Langerhans cell histiocytosis (LCH).The aim of this study was to assess the role of F-18-FDG PET/CT in the diagnosis and treatment of LCH.Methods Eight newly diagnosed and seven recurrent patients with LCH received F-18-FDG PET/CT scans.The diagnosis of LCH was established by pathology,multi-modality imaging,and clinical follow-up.Results F-18-FDG PET/CT was positive in 14 patients with 13 true positives and one false positive.All 45 LCH lesions were F-18-FDG avid including six small bone lesions ＜1.0 cm in diameter.The mean maximal standardized uptake value (SUVmax) was 7.13±4.91.F-18-FDG uptake showed no significant difference between newly diagnosed lesions vs recurrent lesions (SUVmax:6.50±2.97 vs.7.93±6.60,t=-0.901,P=0.376).Among 45 LCH lesions,68.9％ (31/45) were found in bones and 31.1％ (14/45) in soft tissue.The most commonly involved bones were the pelvis and vertebrae.There was no significant difference in F-18-FDG uptake between bone lesions vs.non-bone lesions (SUVmax:6.30±2.87 vs.8.97±7.58,t=1.277,P=0.221).In two patients,changes in F-18-FDG uptake on serial PET/CT scans reflected response of lesions to treatment.Conclusions The present study suggests that F-18-FDG PET/CT may be useful for diagnosis and assessing the treatment response of LCH.Because of the small sample size,further research is warranted to confirm our findings.

Proceedings of the Seminar on Research Result of Research Reactor Technology Centre 2003

International Nuclear Information System (INIS)

Endiah Puji Hastuti; Setiyanto; Taswanda Taryo; Mohammad Dhandhang Purwadi; Pinem, Surian; Tarigan, Alim; Hasibuan, Djaruddin; Kadarusmanto; Amir Hamzah

2004-05-01

The Proceeding of the Seminar on Research Result of Research Reactor Technology Centre 2003 held by P2TRR has been reported researcher are expected to use the reports as references to research activities in Science and Technology, especially in field of Nuclear Reactor. There are 27 papers which have separated index. (PPIN)

Annual Report 1979. Research Institute of physics Stockholm

International Nuclear Information System (INIS)

1979-01-01

Following a list of the research personnel, brief reports are presented on research projects in the fields of surface, atomic and molecular physics, atomic and molecular theory, nuclear physics, nuclear theory, exotic atoms and instrumentation and methods. There follow lists of seminars held, publications, theses and the main topics of a workshop on very stable nuclear systems held at Kornoe, 26-28 Aug 1979. (JIW)

14th meeting of the IFRC Subcommittee on Atomic and Molecular Data for Fusion. Summary report of IAEA technical meeting

International Nuclear Information System (INIS)

Clark, R.E.H.; Peacock, N.J.

2006-01-01

The 14th Meeting of the Subcommittee on Atomic and Molecular Data for Fusion of the International Fusion Research Council was held on 24-25 June 2004, at the IAEA Headquarters in Vienna, Austria. Subcommittee members reviewed the work of the Atomic and Molecular Data Unit over the two-year period from June 2002 to June 2004, and made recommendations that covered the 2005-2006 budget cycle. The proceedings, conclusions and recommendations of the meeting are briefly described in this report, along with a short summary of the activities of the IAEA Atomic and Molecular Data Unit of the Nuclear Data Section from June 2002 to June 2004. (author)

Study of some excited states in 21Ne-21Na, 18O-18F and 15N-15O nuclei

International Nuclear Information System (INIS)

Drain, D.

1977-01-01

The study of 21 Ne- 21 Na, 18 O- 18 F and 15 N- 15 O nuclei was performed through proton capture and transfer reactions and allows to determine the spins and parities of some excited states, give the gamma deexcitation schemes of these levels, compute the neutron and proton reduced width γ 2 sub(n) and γ 2 sub(p). The levels studied are: in 21 Na 4.15 20 Ne(p,p), (p,p'), (p,p'γ) and (pγ) reactions) and in 21 Ne: E(exc)=4.73, 5.69 and 5.78 MeV ( 20 Ne (p,p) reaction); in 18 O: E(exc) 17 O(d,p) reaction); in 15 O: 8.92 MeV doublet and 8.98 MeV level (angular correlation 14 N(p,γγ) and in 15 N: 9.05 14 N(d,p) reaction). A comparison with theoretical results is discussed and analog states are pointed out [fr

First meeting of the International Working Group on Advanced Technologies for Water Cooled Reactors, Vienna, 18-21 May 1987. (Pt. 1)

International Nuclear Information System (INIS)

1987-12-01

The first meeting of the IAEA International Working Group on Advanced Technologies for Water Cooled Reactors was held in Vienna, Austria from 18-21 May 1987. Part I of the Summary Report contains the minutes of the meeting

National Plan for Research - Development and Innovation, CERES Programme. Annual Scientific Session

International Nuclear Information System (INIS)

Ionescu-Bujor, Theodor; Dobrescu, Serban

2002-01-01

The CERES Programme is a research program organized in the frame of Institut of Atomic Physics, Bucharest, Romania. The annual scientific session held in Bucharest on December 2-3, 2002 covered the following 9 sections (projects): Mathematics (2); Physics (85); Chemistry (14); Engineering (2); Earth Sciences (13); Life Sciences (8); Economics and Social Studies (4); Culture (4); Works received after the deadline. The most numerous contributions within the INIS scope addressed subjects from the fields: theoretical and experimental nuclear physics, seismic survey and prognoses, high energy physics and quantum field theory, physical properties of materials, nuclear spectroscopic instrumentation, nuclear methods in isotopic analysis. The contributors presented their results obtained under research contracts supported by the Romanian Ministry of Education and Research in the period October 15, 2001 - October 15, 2002. Many of the reported research works were done in collaborations with international organizations or institutes from abroad

Transmutation research and fuel cycle (report on discussion at Research Reactor Institute, Kyoto University)

International Nuclear Information System (INIS)

Yamana, Hajimu

1999-01-01

A symposium was held on a topic of 'Transmutation Research' on Dec. 21 and 22, 1999 at Research Reactor Institute, Kyoto University. This meeting was held as a joint-meeting of KUR's specialist meeting and Tokyo University's activity supported by the Grant-in-Aid for Scientific Research of Ministry of Education, Sport and Culture of Japan. This paper describes the overview of the discussions of this joint-meeting, and interprets their significance. Major themes discussed are, needed discussions on the transmutation research, policy and concepts of the organizations doing transmutation researches, a view from university side, transmutation researches in the oversea countries, opinions from various standpoints of the nuclear fuel cycle, conclusive discussions. 'the meanings of the transmutation research should be discussed together with the geological disposal and fast reactor system', 'transmutation may be a cooperative option for the disposal, thus, they should not be in a independent relation', and Balance evaluation will be needed' are the examples of the conclusive remarks of this meeting. (author)

Progresses in neuroproteomics of neurodegenerative diseases--18th HUPO BPP workshop: September 12, 2012, Boston, USA.

Science.gov (United States)

Gröttrup, Bernd; May, Caroline; Meyer, Helmut E; Grinberg, Lea T; Park, Young Mok

2013-01-01

The HUPO Brain Proteome Project (HUPO BPP) held its 18(th) workshop in Boston, USA, September 12(th) 2012 during the HUPO 11th Annual Word Congress. The focus was on the progress on the Human Brain Proteome Atlas as well as ideas, strategies and methodological aspects. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

1997 Gordon Research Conference on Plant Cell Walls. Final progress report

Energy Technology Data Exchange (ETDEWEB)

Staehelin, A.

1999-08-25

The Gordon Research Conference (GRC) on Plant Cell Walls was held at Tilton School, Tilton, New Hampshire, July 18-22, 1997. The conference was well attended with 106 participants. The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both US and foreign scientists, senior researchers, young investigators, and students. In designing the formal speakers program, emphasis was placed on current unpublished research and discussion of the future target areas in this field. There was a conscious effort to stimulate lively discussion about the key issues in the field today. Time for formal presentations was limited in the interest of group discussions. In order that more scientists could communicate their most recent results, poster presentation time was scheduled. In addition to these formal interactions, free time was scheduled to allow informal discussions. Such discussions are fostering new collaborations and joint efforts in the field.

75 FR 57844 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2010-09-23

... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... Previously Held by Israel Aircraft Industries, Ltd.): Amendment 39-16438. Docket No. FAA-2010-0555... (Type Certificate previously held by Israel Aircraft Industries, Ltd.) Model Galaxy and Gulfstream 200...

77 FR 64767 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2012-10-23

... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes AGENCY... airworthiness directive (AD) for certain Gulfstream Aerospace LP (Type Certificate previously held by Israel... Certificate previously held by Israel Aircraft Industries, Ltd.) Model Galaxy and Gulfstream 200 airplanes...

78 FR 11567 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2013-02-19

... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream G150... Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.): Amendment 39...

76 FR 70040 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2011-11-10

... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... Aerospace LP (type certificate previously held by Israel Aircraft Industries, Ltd.) Model Galaxy and... new AD: 2011-23-07 Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft...

76 FR 6525 - Airworthiness Directives; Cessna Aircraft Company (Type Certificate Previously Held by Columbia...

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2011-02-07

... Airworthiness Directives; Cessna Aircraft Company (Type Certificate Previously Held by Columbia Aircraft... following new AD: 2011-03-04 Cessna Aircraft Company (Type Certificate Previously Held by Columbia Aircraft... the following Cessna Aircraft Company (type certificate previously held by Columbia Aircraft...

75 FR 27504 - Substantial Product Hazard List: Hand-Held Hair Dryers

Science.gov (United States)

2010-05-17

... immersion during their use. Section 15(a) of the CPSA defines ``substantial product hazard'' to include, a....'' Hand-held hair dryers routinely contain open-coil heating elements that are, in essence, uninsulated..., bathtub, or lavatory). The proposed rule would define ``hand-held hair dryer'' as ``an electrical...

Computer Science Research at Langley

Science.gov (United States)

Voigt, S. J. (Editor)

1982-01-01

A workshop was held at Langley Research Center, November 2-5, 1981, to highlight ongoing computer science research at Langley and to identify additional areas of research based upon the computer user requirements. A panel discussion was held in each of nine application areas, and these are summarized in the proceedings. Slides presented by the invited speakers are also included. A survey of scientific, business, data reduction, and microprocessor computer users helped identify areas of focus for the workshop. Several areas of computer science which are of most concern to the Langley computer users were identified during the workshop discussions. These include graphics, distributed processing, programmer support systems and tools, database management, and numerical methods.

Algorithms for a hand-held miniature x-ray fluorescence analytical instrument

International Nuclear Information System (INIS)

Elam, W.T.; Newman, D.; Ziemba, F.

1998-01-01

The purpose of this joint program was to provide technical assistance with the development of a Miniature X-ray Fluorescence (XRF) Analytical Instrument. This new XRF instrument is designed to overcome the weaknesses of spectrometers commercially available at the present time. Currently available XRF spectrometers (for a complete list see reference 1) convert spectral information to sample composition using the influence coefficients technique or the fundamental parameters method. They require either a standard sample with composition relatively close to the unknown or a detailed knowledge of the sample matrix. They also require a highly-trained operator and the results often depend on the capabilities of the operator. In addition, almost all existing field-portable, hand-held instruments use radioactive sources for excitation. Regulatory limits on such sources restrict them such that they can only provide relatively weak excitation. This limits all current hand-held XRF instruments to poor detection limits and/or long data collection times, in addition to the licensing requirements and disposal problems for radioactive sources. The new XRF instrument was developed jointly by Quantrad Sensor, Inc., the Naval Research Laboratory (NRL), and the Department of Energy (DOE). This report describes the analysis algorithms developed by NRL for the new instrument and the software which embodies them

CONFERENCES AND SYMPOSIA: Commemoration of the centenary of the birth of Academician L A Artsimovich(Scientific session of the Physical Sciences Division of the Russian Academy of Sciences, 18 February 2009; Joint session of the Research Council of the Russian Research Centre 'Kurchatov Institute', the Presidium of the Russian Academy of Sciences, and the Rosatom State Corporation, 18 March 2009)

Science.gov (United States)

Khalatnikov, Isaak M.; Fortov, Vladimir E.; Makarov, Aleksandr A.; Fridman, Aleksei M.; Martynenko, Yurii V.

2009-12-01

The scientific session of the Physical Sciences Division of the Russian Academy of Sciences (RAS) devoted to the centenary of the birth of Academician L A Artsimovich was held on 18 February 2009 in the conference hall of the P N Lebedev Physical Institute, RAS. The following reports were presented at the session: (1) Khalatnikov I M (L D Landau Institute of Theoretical Physics, RAS, Chernogolovka, Moscow region) "Nonaccidental coincidences (Lev Andreevich Artsimovich)"; (2) Pashinin P P (A M Prokhorov Institute of General Physics, RAS, Moscow) "L A Artsimovich and inertial thermonuclear fusion"; (3) Fortov V E (Institute of Thermophysics of Extreme States of the Joint Institute for High Temperatures, RAS, Moscow) "High-power shock waves and extreme states of plasma"; (4) Fridman A M (Institute of Astronomy, RAS, Moscow) "Prediction and discovery of ultrastrong hydrodynamic instabilities caused by a velocity jump: theory and experiment"; (5) Smirnov V P (Russian Research Centre 'Kurchatov Institute', Moscow) "Retracing Artsimovich's path to the thermonuclear source of energy". On 18 March 2009, a joint session of the Learned Council of the Russian Research Centre 'Kurchatov Institute' (RNTsKI in Russ. abbr.), the Presidium of the Russian Academy of Sciences, and the Rosatom State Corporation took place at RNTsKI; the session was devoted to the 100th anniversary of the birth of Academician L A Artsimovich. The following talks were presented at the session: (1) Velikhov E P (Russian Research Centre 'Kurchatov Institute', Moscow) "Academician L A Artsimovich—the founder of our field of science and industry"; (2) Smirnov V P (Russian Research Centre 'Kurchatov Institute', Moscow) "Retracing Artsimovich's path to the thermonuclear source of energy"; (3) Boyarchuk A A (Division of General Physics and Astronomy, RAS, Moscow) "L A Artsimovich and astronomy"; (4) Martynenko Yu V (Institute of Nuclear Fusion, Russian Research Centre 'Kurchatov Institute', Moscow

Establishment of an international reference data library of nuclear activation cross sections. Summary report of the first research co-ordination meeting held in Debrecen, Hungary, from 4 to 7 October 1994

International Nuclear Information System (INIS)

Pashchenko, A.B.

1995-02-01

The report contains the Summary of the First IAEA Research Co-ordination Meeting (RCM) of the new Co-ordinated Research Programme (CRP) on ''Establishment of an International Reference Data Library of Nuclear Activation Cross Sections''. The meeting was organized by the IAEA Nuclear Data Section with co-operation and assistance of local organizers from the Institute of Experimental Physics and held in Debrecen, Hungary, from 4 to 7 October 1994. The purpose of the RCM was to discuss the scope and goals of the CRP, to report and evaluate the first results of the research carried out by each participating laboratory, to review the current tasks, identify further actions of participants and agree on the coordination of work under this CRP. The detailed agenda, the list of participants, conclusions and recommendations of the meeting are presented in the summary report. (author)

Salivary cortisol, alpha-amylase and immunoglobulin a responses to a morning session of basketball or volleyball training in boys aged 14-18 years.

Science.gov (United States)

Bruzda-Zwiech, A; Konieczka, M; Hilt, A; Daszkowska, M; Grzegorczyk, J; Szczepańska, J

2017-01-01

This study investigates whether a single session of routine morning basketball or volleyball training affects saliva levels of cortisol, alpha-amylase (sAA) and secretory immunoglobulin A (sIgA) in boys aged 14–18 years. Twenty-nine boys who participate in basketball or volleyball training, recruited from the Marcin Gortat’s Athletic Championship School in Lodz, were enrolled in the study. The 90-minute routine exercise program included 15 minutes of warm-up followed by basketball or volleyball practice. Unstimulated saliva samples were collected prior to and immediately after the exercise, and were analysed using ELISA. One training session resulted in a significant increase of sAA concentration in all participants, as well as in the volleyball and basketball subgroups (p=0.00022; p=0.0029; p=0.0011; respectively). Post-exercise cortisol levels were significantly lower than pre-exercise levels (p=0.00002) throughout the group, as well as in the volleyball and basketball subgroups (p=0.0048; p=0.0019; p=0.0048; respectively). The exercise protocol did not significantly affect sIgA level, either in the whole examined group or the volleyball subgroup, however a weak significant increase of sIgA was observed in the basketball subgroup (p=0.046). The routine morning training session comprising a warm-up followed by basketball or volleyball practice seems to activate the sympatho-adrenal-medullary system, with a subsequent increase of alpha-amylase, but does not affect oral immunity in 14-18-year-old boys.

Cumulative abstracts of Cryogenic Technology Section proceedings of the Meeting on Engineering and Technology in Basic Research 1982-2003

International Nuclear Information System (INIS)

Ikeda, Hiroshi

2005-01-01

The Cryogenic Technology Section in the Meeting on Engineering and Technology in Basic Research had been held by Institute of Molecular Science, Plasma Research Center and KEK since 1976. The abstracts of papers and reports read in the meeting on engineering and technology in basic research from 1982 to 2003 are classified by five parts. The first part includes 22 papers on automation system; the second part contains 17 papers on cryostat production; the third part 31 papers on peripheral device; the forth 23 papers on production of cryogenic device and the fifth 18 papers on repair and management of cryogenic device. Further information is able to be obtained by each homepage. (S.Y.)

Research reactor DHRUVA

International Nuclear Information System (INIS)

Veeraraghaven, N.

1990-01-01

DHRUVA, a 100 MWt research reactor located at the Bhabha Atomic Research Centre, Bombay, attained first criticality during August, 1985. The reactor is fuelled with natural uranium and is cooled, moderated and reflected by heavy water. Maximum thermal neutron flux obtained in the reactor is 1.8 X 10 14 n/cm 2 /sec. Some of the salient design features of the reactor are discussed in this paper. Some important features of the reactor coolant system, regulation and protection systems and experimental facilities are presented. A short account of the engineered safety features is provided. Some of the problems that were faced during commissioning and the initial phase of power operation are also dealt upon

The Fifteenth International Conference on the Science and Application of Nanotubes (NT14)

Energy Technology Data Exchange (ETDEWEB)

cronin, stephen

2015-01-06

The Fifteenth International Conference on the Science and Application of Nanotubes (NT14) was held at the University of Southern California in Los Angeles, California on June 2-6, 2014. NT14 upheld the NT tradition of presenting the latest results in the science and applications of nanotubes and related materials in plenary sessions. Emphasis was given to convivial poster sessions and student participation. Over 225 participants attended the conference, including students, post-docs, faculty, and members from industry. A total of 45 talks were presented, as well as 157 posters.

75 FR 28485 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2010-05-21

... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.): Amendment 39... previously held by Israel Aircraft Industries, Ltd.) Model Gulfstream 100 airplanes; and Model Astra SPX and...

Conceptions of the Nature of Science Held by Undergraduate Pre-Service Biology Teachers in South-West Nigeria

Science.gov (United States)

Adedoyin, A. O.; Bello, G.

2017-01-01

This study investigated the conceptions of the nature of science held by pre-service undergraduate biology teachers in South-West, Nigeria. Specifically, the study examined the influence of their gender on their conceptions of the nature of science. The study was a descriptive research of the survey method. The population for the study comprised…

TWEAK-independent Fn14 self-association and NF-κB activation is mediated by the C-terminal region of the Fn14 cytoplasmic domain.

Directory of Open Access Journals (Sweden)

Sharron A N Brown

Full Text Available The tumor necrosis factor (TNF superfamily member TNF-like weak inducer of apoptosis (TWEAK is a pro-inflammatory and pro-angiogenic cytokine implicated in physiological tissue regeneration and wound repair. TWEAK binds to a 102-amino acid type I transmembrane cell surface receptor named fibroblast growth factor-inducible 14 (Fn14. TWEAK:Fn14 engagement activates several intracellular signaling cascades, including the NF-κB pathway, and sustained Fn14 signaling has been implicated in the pathogenesis of chronic inflammatory diseases and cancer. Although several groups are developing TWEAK- or Fn14-targeted agents for therapeutic use, much more basic science research is required before we fully understand the TWEAK/Fn14 signaling axis. For example, we and others have proposed that TWEAK-independent Fn14 signaling may occur in cells when Fn14 levels are highly elevated, but this idea has never been tested directly. In this report, we first demonstrate TWEAK-independent Fn14 signaling by showing that an Fn14 deletion mutant that is unable to bind TWEAK can activate the NF-κB pathway in transfected cells. We then show that ectopically-expressed, cell surface-localized Fn14 can self-associate into Fn14 dimers, and we show that Fn14 self-association is mediated by an 18-aa region within the Fn14 cytoplasmic domain. Endogenously-expressed Fn14 as well as ectopically-overexpressed Fn14 could also be detected in dimeric form when cell lysates were subjected to SDS-PAGE under non-reducing conditions. Additional experiments revealed that Fn14 dimerization occurs during cell lysis via formation of an intermolecular disulfide bond at cysteine residue 122. These findings provide insight into the Fn14 signaling mechanism and may aid current studies to develop therapeutic agents targeting this small cell surface receptor.

Synthesis of [14α, 15α-3H]-norgestrel

International Nuclear Information System (INIS)

Wagner, H.

1988-01-01

The preparation of the well-known gestogen norgestrel in a tritium labelled form is described. Starting material was 18-methyl-3-methoxy-estra-1,3,5(10),8,14-pentaen-17β-o1 acetate. In a four step synthesis 17α-ethinyl-17β-hydroxy-18-methyl-[14α,15α- 3 H]-estr-4-en-3-one was obtained with a specific activity of 52 Ci/mmol and a radiochemical purity > 99%. (author)

EDITORIAL: The 18th Central European Workshop on Quantum Optics The 18th Central European Workshop on Quantum Optics

Science.gov (United States)

Sánchez-Soto, Luis L.; Man'ko, Margarita A.

2012-02-01

to the proceedings of the 15th CEWQO (Physica Scripta 2009 T135 011005). The 18th edition of CEWQO (CEWQO11) was held in Madrid in 2011. There were about 250 participants, from practically every European country. Many colleagues from other continents also joined the event, including well-established researchers in the field. This is a clear demonstration that these meetings provide an excellent chance to hear about the latest results and new directions of research. The organization of CEWQO11 was carried out by a committee consisting of members active in this topic in Madrid. From Universidad Complutense, Alberto Galindo and Luis L Sánchez-Soto from Universidad Autónoma, Jose Calleja and Carlos Tejedor; from Universidad Politécnica, Enrique Calleja; from Universidad Carlos III, Alberto Ibort; and from the National Research Council (CSIC), Juan León and Juan J García-Ripoll. Special thanks go to the Spanish Ministry for Science and Innovation, Universidad Complutense and the Quitemad Consortium for financial support. The proceedings of the 16th CEWQO held at the University of Turku, Finland and the 17th CEWQO held at the University of St Andrews, Scotland, UK are also available (Physica Scripta 2010 T140 and Physica Scripta 2011 T143). The present Topical Issue is a collection of papers presented in Madrid; they represent an illustrative sample of the major achievements and trends in this area. In turn, they reflect the wide range of interests in this rapidly evolving field. Some collaborators from different scientific centres who could not, due to different reasons, come to Madrid, but participated in previous CEWQOs and plan to participate in future CEWQOs, also contributed to this issue. The papers are arranged alphabetically by the name of the first author. Special thanks goes to Roger Wäppling, the Managing Editor of Physica Scripta, and Graeme Watt, the Publisher, for the opportunity to publish CEWQO11. From a Physica Scripta Editorial Board meeting it was

2. IAEA research co-ordination meeting on 'Data for molecular processes in edge plasmas'. Summary report

International Nuclear Information System (INIS)

Clark, R.E.H.

2004-05-01

This report briefly describes the proceedings, conclusions and recommendations of the 2nd Research Co-ordination Meeting (RCM) of the Co-ordinated Research Project (CRP) on 'Data for Molecular Processes in Edge Plasmas' held on 12-14 May 2003 at IAEA Headquarters, Vienna. During the course of the meeting the progress achieved to data was thoroughly reviewed. During the course of the meeting many areas in need of further research were noted. In addition there are specific important processes with lingering discrepancies between theory and experiment. Strong collaborations built during the course of this CRP have the potential to address these issues. Therefore, one outcome of the RCM was a detailed proposal to extend the CRP for an additional year with a final RCM in 2004. (author)

26 CFR 301.7701-14 - Cooperative bank.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 18 2010-04-01 2010-04-01 false Cooperative bank. 301.7701-14 Section 301.7701... ADMINISTRATION PROCEDURE AND ADMINISTRATION Definitions § 301.7701-14 Cooperative bank. For taxable years beginning after October 16, 1962, the term “cooperative bank” means an institution without capital stock...

2014 World Conference on Information Systems and Technologies

CERN Document Server

Correia, Ana; Tan, Felix; Stroetmann, Karl

2014-01-01

This book contains a selection of articles from The 2014 World Conference on Information Systems and Technologies (WorldCIST'14), held between the 15th and 18th of April in Funchal, Madeira, Portugal, a global forum for researchers and practitioners to present and discuss recent results and innovations, current trends, professional experiences and challenges of modern Information Systems and Technologies research, technological development and applications. The main topics covered are: Information and Knowledge Management; Organizational Models and Information Systems; Intelligent and Decision Support Systems; Software Systems, Architectures, Applications and Tools; Computer Networks, Mobility and Pervasive Systems; Radar Technologies; Human-Computer Interaction; Health Informatics; and Information Technologies in Education.

Defining features of the practice of global health research: an examination of 14 global health research teams

Directory of Open Access Journals (Sweden)

Craig Stephen

2010-07-01

Full Text Available Objectives: This paper strives to develop a pragmatic view of the scope of practice and core characteristics of global health research (GHR by examining the activities of 14 Canadian-funded global health teams that were in the process of implementing research programs. Methods: Information was collected by a reflective exploration of team proposals and progress reports, a content analysis of the outputs from an all-team meeting and review of the literature. Results: Teams adopted equity-centered, problem-focused, systems-based approaches intended to find upstream determinants that could make people more resilient to social and ecological factors impacting their health. Long-term visions and time frames were needed to develop and solidify fully functional interdisciplinary, multinational, multicultural partnerships. The implementation of research into practice was a motivating factor for all teams, but to do this, they recognized the need for evidence-based advice on how to best do this. Traditional measures of biomedical research excellence were necessary but not sufficient to encompass views of excellence of team-based interdisciplinary research, which includes features like originality, coherence and cumulative contributions to fields of study, acceptance by peers and success in translating research into gains in health status. An innovative and nuanced approached to GHR ethics was needed to deal with some unique ethical issues because the needs for GHR were not adequately addressed by institutional biomedical research ethics boards. Core competencies for GHR researchers were a blend of those needed for health promotion, population health, international development, sustainable development, and systems science. Discussion: Developing acceptable and meaningful ways to evaluate the short-term contributions for GHR and forecast its long-term impacts is a strategic priority needed to defend decisions being made in GHR development. Planning and

Effects of pH upon the environmental fate of [14C]fenitrothion in an aquatic microcosm

International Nuclear Information System (INIS)

Fisher, S.W.

1985-01-01

The environmental fate of [ 14 C]fenitrothion was evaluated in aquatic microcosms held at pH 8.3 or 6.7. No general effect attributable to pH was observed; however, several significant interactions were identified. Of these, the findings that statistically higher amounts of radioactivity were present in water held at pH 6.7 and that significantly less metabolism of the parent compound occurred in the organisms at pH 8.3 were preeminent. These differences seen in metabolism and environmental fate between pH values are relatively minor and do not compromise the safety of the compound

Summary record: Workshop on alternatives to chlorofluorocarbons as solvents. Held in Irvine, California on June 17-18, 1991

International Nuclear Information System (INIS)

1991-06-01

The impetus for minimization or elimination of chlorofluorocarbons (CFCs) comes from the growing body of knowledge concerning depletion of the stratospheric ozone layer and formation of polar ozone 'holes'. The workshop concentrated on solvent usage, which constitutes some 12% of CFCs contribution to ozone depletion and is estimated by the U.S. Environmental Protection Agency (EPA) at a sales dollar volume of $145 million per year for the United States alone. There is widespread solvent use in the electronics, automotive, defense, and spacecraft industries, as well as by a myriad of smaller fabricators and for consumer products. Seventeen major corporations in collaboration with the EPA, have formed the Industry Cooperative for Ozone Layer Protection (ICOLP). Two meetings were held prior to the workshop. The first included presentations by representatives from the ICOLP member companies on the pertinent activities of their respective organizations. The objective of this meeting was to brief the steering committee on the needs, limitations, problems, and successes in the development of alternatives to CFCs. Much of the background material presented in the workshop report was compiled during this first meeting. The objectives of the second meeting of the steering committee were to plan the agenda for the workshop and to identify the industry representatives to be invited

75 FR 29722 - Foreign-Trade Zone 18-San Jose, CA; Application for Subzone; Lam Research Corporation (Wafer...

Science.gov (United States)

2010-05-27

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket 36-2010] Foreign-Trade Zone 18--San Jose, CA; Application for Subzone; Lam Research Corporation (Wafer Fabrication Equipment Manufacturing); Fremont, Newark, and Livermore, CA An application has been submitted to the Foreign-Trade Zones Board (the Board) by the City of San Jose, grantee of...

Chronologies in wood and resin: AMS 14C dating of pre-Hispanic Caribbean Wood Sculpture

Science.gov (United States)

Joanna Ostapkowicz; Christopher Bronk-Ramsey; Fiona Brock; Tom Higham; Alex C. Wiedenhoeft; Erika Ribechini; Jeannette J. Lucejko; Samuel. Wilson

2012-01-01

This paper establishes a chronological framework for selected pieces of Caribbean (Tafno/Lucayan) wooden sculpture, enabling previously ahistoric artefacts to fit back into the wider corpus of pre-colonial material culture. Seventy-two 14C AMS determinations from 56 artefacts held in museum collections are reported, including 32 ceremonial

International Joint Conference SOCO’14-CISIS’14-ICEUTE’14

CERN Document Server

Ferreira, Iván; Bringas, Pablo; Klett, Fanny; Abraham, Ajith; Carvalho, André; Herrero, Álvaro; Baruque, Bruno; Quintián, Héctor; Corchado, Emilio

2014-01-01

This volume of Advances in Intelligent and Soft Computing contains accepted papers presented at SOCO 2014, CISIS 2014 and ICEUTE 2014, all conferences held in the beautiful and historic city of Bilbao (Spain), in June 2014. Soft computing represents a collection or set of computational techniques in machine learning, computer science and some engineering disciplines, which investigate, simulate, and analyze very complex issues and phenomena.   After a through peer-review process, the 9th SOCO 2014 International Program Committee selected 31 papers which are published in these conference proceedings. In this relevant edition a special emphasis was put on the organization of special sessions. One special session was organized related to relevant topics as: Soft Computing Methods in Manufacturing and Management Systems.   The aim of the 7th CISIS 2014 conference is to offer a meeting opportunity for academic and industry-related researchers belonging to the various, vast communities of Computational Intelligen...

Enlarged test catalysts during the hydrogenation of 1,4-butynediol to 1,4-butanediol

Directory of Open Access Journals (Sweden)

Zhaksyntay Kairbekov

2013-09-01

Full Text Available The highly effective catalyzer for butynediol-1;4 hydrogenation was designed and synthesized. Enlarged tests showed that the selectivity on butanediol-1.4 at the hydrogenation of butynediol-1.4 on the alloyed catalyst SKN-39H during 320 h was 84.6 %; that on 18 % higher than for  industrial MNH. The yield of product on the catalyst SKN-39 increases slowly from 3.1 to 7.3 % when on a catalyst MNH – 7.1 to 11.7 % from the initial content of butynediol-1;4. At the hydrogenation of  butynediol on catalyst SKN-39H process efficiency increases in 1.5-2 times and product purity on 2-3 % is higher in comparing with the industrial catalyst MNH. 

Intercomparison of liquid metal fast reactor seismic analysis codes. V.1: Validation of seismic analysis codes using reactor core experiments. Proceedings of a research co-ordination meeting held in Vienna, 16-17 November 1993

International Nuclear Information System (INIS)

1995-05-01

The Research Co-ordination Meeting held in Vienna, 16-17 November 1993, was attended by participants from France, India, Italy, Japan and the Russian Federation. The meeting was held to discuss and compare the results obtained by various organizations for the analysis of Italian tests on PEC mock-up. The background paper by A. Martelli, et al., Italy, entitled Fluid-Structure Interaction Experiments of PEC Core Mock-ups and Numerical Analysis Performed by ENEA presented details on the Italian PEC (Prova Elementi di Combustibile, i.e. Fuel Element Test Facility) test data for the benchmark. Several papers were presented on the analytical investigations of the PEC reactor core experiments. The paper by M. Morishita, Japan, entitled Seismic Response Analysis of PEC Reactor Core Mock-up, gives a brief review of the Japanese data on the Monju mock-up core experiment which had been distributed to the participating countries through the IAEA. Refs, figs and tabs

Conference: “Space and Research: Which future for the coming generation” | 18 September | Uni Mail

CERN Multimedia

Stefania Pandolfi

2015-01-01

  On Friday, 18 September, Luca Parmitano (Major in the Italian Air Force and European Space Agency astronaut), Guido Tonelli (CERN phycisist) and Amalia Ercoli Finzi (Emeritus Professor in the Aerospace department of the Polytechnic University of Milan and a Principal Investigator of the ESA Rosetta spacecraft) will present their visions of the future of research and space exploration. Free entrance. Limited number of seats - registration is essential, click here. For more information contact fc-italie@unige.ch.

Electrical conductivity, differential scanning calorimetry, X-ray diffraction, and 7Li nuclear magnetic resonance studies of n-C x H(2 x+1)OSO3Li ( x = 12, 14, 16, 18, and 20)

Science.gov (United States)

Hirakawa, Satoru; Morimoto, Yoshiaki; Honda, Hisashi

2015-04-01

Electrical conductivity ( σ), differential scanning calorimetry (DSC), and X-ray diffraction (XRD) measurements of n-C x H (2 x+1) OSO 3Li ( x= 12, 14, 16, 18, and 20) crystals were performed as a function of temperature. In addition, σ, DSC, and XRD observations of n-C x H (2 x+1) OSO 3Na and n-C x H (2 x+1) OSO 3K ( x= 12, 14, 16, 18, and 20) crystals were carried out for comparison. DSC results of the salts revealed several solid-solid phase transitions with large entropy changes (Δ S). For n-C 18 H 37 OSO 3Li and n-C 20 H 41 OSO 3Li salts, each melting point produced a small Δ S mp value compared with the total entropy change in the solid phases (Δ S tr1+Δ S tr2). Additionally, Li + ion diffusion was detected in the highest temperature solid phases. For K salts, larger σ values were detected for potassium alkylsulfates compared with those reported for alkyl carboxylate. 7Li NMR spectra of n-C 18 H 37 OSO 3Li crystals recorded in the low-temperature phase showed large asymmetry parameters, suggesting the Li + ions are localized at asymmetric sites in the crystals.

14(R,S)-[{sup 18}F]Fluoro-6-thia-heptadecanoic acid as a tracer of free fatty acid uptake and oxidation in myocardium and skeletal muscle

Energy Technology Data Exchange (ETDEWEB)

Takala, Teemu O.; Nuutila, Pirjo [Turku PET Centre, Turku University Central Hospital, PO Box 52, 20521 Turku (Finland); Department of Medicine, University of Turku (Finland); Pulkki, Kari [Department of Clinical Chemistry, University of Turku (Finland); Oikonen, Vesa; Groenroos, Tove; Bergman, Joergen; Forsback, Sarita; Knuuti, Juhani [Turku PET Centre, Turku University Central Hospital, PO Box 52, 20521 Turku (Finland); Savunen, Timo; Vaehaesilta, Tommi [Department of Surgery, University of Turku (Finland); Luotolahti, Matti [Department of Clinical Physiology, University of Turku (Finland); Kallajoki, Markku [Department of Pathology, University of Turku (Finland)

2002-12-01

14(R,S)-[{sup 18}F]Fluoro-6-thia-heptadecanoic acid ([{sup 18}F]FTHA) is a long-chain fatty acid substrate for fatty acid metabolism. [{sup 18}F]FTHA has been used to study fatty acid metabolism in human heart and skeletal muscle. It has been suggested that the rate of radioactivity accumulation in the myocardium reflects the beta-oxidation rate of free fatty acids (FFAs). However, the net accumulation of FFAs in tissue always represents the sum of FFA oxidation and incorporation into triglycerides. The fraction of [{sup 18}F]FTHA entering directly into mitochondria for oxidation has not been previously measured. Eight anaesthetized pigs were studied with [{sup 18}F]FTHA and positron emission tomography (PET). Immediately after each PET experiment, tissue samples from myocardium and skeletal muscle were taken for the isolation of mitochondria and measurements of radioactivity accumulation, and for intracellular [{sup 18}F]FTHA metabolite analysis. Fractional [{sup 18}F]FTHA uptake rates were calculated both by graphical analysis of PET data and by measuring {sup 18}F in the tissue samples. Fractional [{sup 18}F]FTHA uptake rates based on the analysis of tissue samples were 0.56{+-}0.17 ml g{sup -1} min{sup -1} and 0.037{+-}0.007 ml g{sup -1} min{sup -1} for myocardium and skeletal muscle (mean {+-} SD), respectively. The myocardial results obtained from the PET data (0.50{+-}0.11 ml g{sup -1} min{sup -1}) were similar to the values obtained from the tissue samples (r=0.94, P=0.002). We also found that 89%{+-}23% (mean{+-}SD, n=7) of the {sup 18}F entered mitochondria in myocardium, as compared with only 36%{+-}15% (mean{+-}SD, n=7) in skeletal muscle. Intracellular [{sup 18}F]FTHA metabolite analysis showed that a major part of [{sup 18}F]FTHA is metabolized in the mitochondria in the heart. Our data suggest that 89% of [{sup 18}F]FTHA taken up by the heart enters mitochondria. This supports the hypothesis that [{sup 18}F]FTHA traces FFA beta-oxidation in the heart

2016 MATRIX annals

CERN Document Server

Praeger, Cheryl; Tao, Terence

2018-01-01

MATRIX is Australia’s international, residential mathematical research institute. It facilitates new collaborations and mathematical advances through intensive residential research programs, each lasting 1-4 weeks. This book is a scientific record of the five programs held at MATRIX in its first year, 2016: Higher Structures in Geometry and Physics (Chapters 1-5 and 18-21); Winter of Disconnectedness (Chapter 6 and 22-26); Approximation and Optimisation (Chapters 7-8); Refining C*-Algebraic Invariants for Dynamics using KK-theory (Chapters 9-13); Interactions between Topological Recursion, Modularity, Quantum Invariants and Low-dimensional Topology (Chapters 14-17 and 27). The MATRIX Scientific Committee selected these programs based on their scientific excellence and the participation rate of high-profile international participants. Each program included ample unstructured time to encourage collaborative research; some of the longer programs also included an embedded conference or lecture series. The artic...

The perceptions of inquiry held by greater Houston area science supervisors

Science.gov (United States)

Aoki, Jon Michael

of inquiry held by the science teachers whom they work with. Both of these implications may limit the process of integrating inquiry into the classroom. The third implication is that a rubric can be designed based on the results of this study to help determine which categories or components of inquiry the participant needs assistance with. Implications for further research include increasing the sample size, describing the effects of teaching and/or science supervisor experience on the perceptions of inquiry, determining the effects of advanced degrees on inquiry perceptions, and investigating the effects of research experience on inquiry perceptions. (Abstract shortened by UMI.)

Special Issue: 14th International Symposium on Novel and Nano Materials

Science.gov (United States)

Kim, Woo-Byoung; Choa, Yong-Ho; Ahn, Hyo-Jin; Park, Il-Kyu

2017-09-01

This Special Issue of Applied Surface Science is intended to provide a collection of peer-reviewed contributions presented at the 14th International Symposium on Novel Nano Materials (ISNNM) held in Budapest, Hungary as one of the most beautiful cities in Europe from July 3 to July 8, 2016. All selected papers underwent the regular peer review process as set by the journal of Applied Surface Science and its publisher (Elsevier).

Living with Parkinson's disease: priorities for research suggested by patients.

Science.gov (United States)

Schipper, K; Dauwerse, L; Hendrikx, A; Leedekerken, J W; Abma, T A

2014-08-01

To describe a study in which patients with Parkinson's disease (PD) were engaged to list priorities for research to complement the professionals' research agenda. The study was conducted by researchers and people with PD or relatives. Interviews and focus groups were held to develop a research agenda from patients' perspectives. A questionnaire was completed by patients to prioritize the research topics. Voiceover group meetings and meetings with the advisory group were organized to obtain feedback on the research process and to deliberate the preliminary findings. Finally, dialog meetings were organized with stakeholders to discuss the agenda and to achieve a shared research agenda. Patients prioritized 18 research themes. Top priorities included fundamental research, research on medication, coping, family & relations and good care. Patients asked for applied and multidisciplinary research. Professionals and charitable funding bodies acknowledged the importance of such research but did not feel capable of judging such proposals. Patients furthermore asked for more attention to be paid to living with the illness in the here-and-now to complement fundamental research. The patients' research agenda can be used to match research with patients' needs and to adapt the clinical support of professionals to patients' wishes. Copyright © 2014 Elsevier Ltd. All rights reserved.

Teaching through Research: Alignment of Core Chemistry Competencies and Skills within a Multidisciplinary Research Framework

Science.gov (United States)

Ghanem, Eman; Long, S. Reid; Rodenbusch, Stacia E.; Shear, Ruth I.; Beckham, Josh T.; Procko, Kristen; DePue, Lauren; Stevenson, Keith J.; Robertus, Jon D.; Martin, Stephen; Holliday, Bradley; Jones, Richard A.; Anslyn, Eric V.; Simmons, Sarah L.

2018-01-01

Innovative models of teaching through research have broken the long-held paradigm that core chemistry competencies must be taught with predictable, scripted experiments. We describe here five fundamentally different, course-based undergraduate research experiences that integrate faculty research projects, accomplish ACS accreditation objectives,…

Intelligent Virtual Agents : 9th International Conference, IVA 2009 Amsterdam, The Netherlands, September 14-16, 2009 Proceedings

NARCIS (Netherlands)

Ruttkay, Z.M.; Kipp, M.; Nijholt, Antinus; Vilhjalmsson, H.H.

2009-01-01

Welcome to the Proceedings of the 9th International Conference on Intelligent Virtual Agents, held 14-16 September, 2009 in Amsterdam, The Netherlands. Intelligent Virtual Agents (IVAs) are interactive characters that exhibit humanlike qualities and communicate with humans or with each other using

A new (14th) member of Borrelia burgdorferi sensu lato complex

Czech Academy of Sciences Publication Activity Database

Oliver, J.; Rudenko, Natalia; Golovchenko, Maryna; Grubhoffer, Libor

2008-01-01

Roč. 14, S7 (2008), S110-S110 ISSN 1198-743X. [ECCMID /18./. 19.04.2008-22.04.2008, Barcelona] R&D Projects: GA ČR(CZ) GA524/06/1479; GA MŠk(CZ) LC06009 Grant - others:National Institutes of Health (NIH)(US) R37AI-24899; Centers for Disease Control and Prevention (CDC)(US) U50/CCU410282 Institutional research plan: CEZ:AV0Z60220518 Keywords : Borrelia burgdorferi s.l. complex * new member * multilocus sequence analysis Subject RIV: EC - Immunology

Steady-state operation of magnetic fusion devices: Plasma control and plasma facing components. Report on the IAEA technical committee meeting held at Fukuoka, 25-29 October 1999

International Nuclear Information System (INIS)

Engelmann, F.

2000-01-01

An IAEA Technical Committee Meeting on Steady-State Operation of Magnetic Fusion Devices - Plasma Control and Plasma Facing Components was held at Fukuoka, Japan, from 25 to 29 October 1999. The meeting was the second IAEA Techical Committee Meeting on the subject, following the one held at Hefei, China, a year earlier. The meeting was attended by over 150 researchers from 10 countries

Cross section of ternary fission of Al, Ti, Co and Zr nuclei induced by 0,8 - 1,8 Gev photons

International Nuclear Information System (INIS)

Lima, D.A. de; Sousa, E.V. de; Milomen, W.C.C.; Tavares, O.A.P.

1988-01-01

A research on ternary fission of Al, Ti, Co, and Zr nuclei induced by bremsstrahlung photons of 0,8, 1,0, 1,4, and 1,8 Gev end-point energies has been carried out using makrofol polycarbonate and CR-39 polymer as fission-track detectors. Results are discussed and compared with other ternary fission data. (M.W.O.) [pt

LLW Forum meeting report, April 18--19, 1991

International Nuclear Information System (INIS)

1991-01-01

The Low-Level Radioactive Waste Forum is an association of representatives of states and compacts established to facilitate state and compact commission implementation of the Low-Level Radioactive Waste Policy Act of 1980 and the Low-Level Radioactive Waste Policy Amendments Act of 1985 and to promote the objectives of low-level radioactive waste regional compacts. The Forum provides an opportunity for states and compacts to share information with one another and to exchange views with officials of federal agencies. LLW Forum participants include representatives from regional compacts, designated host states, unaffiliated states, and states with currently- operating low-level radioactive waste facilities. This quarterly meeting was held on April 18-19, 1991

Human embryo research and the 14-day rule.

Science.gov (United States)

Pera, Martin F

2017-06-01

In many jurisdictions, restrictions prohibit the culture of human embryos beyond 14 days of development. However, recent reports describing the successful maintenance of embryos in vitro to this stage have prompted many in the field to question whether the rule is still appropriate. This Spotlight article looks at the original rationale behind the 14-day rule and its relevance today in light of advances in human embryo culture and in the derivation of embryonic-like structures from human pluripotent stem cells. © 2017. Published by The Company of Biologists Ltd.

17 CFR 300.102 - Accounts held by executors, administrators, guardians, etc.

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Accounts held by executors... CORPORATION Accounts of âseparateâ Customers of Sipc Members § 300.102 Accounts held by executors... estate or in the name of the executor or administrator of the estate of the decedent shall be combined so...

Report of the evaluation by the Ad Hoc Review Committee on Nuclear Safety Research. Result evaluation in fiscal year 2000

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-06-01

The Research Evaluation Committee, which consisted of 14 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Nuclear Safety Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the R and D accomplishments achieved for five years from Fiscal Year 1995 to Fiscal Year 1999 at Department of Reactor Safety Research, Department of Fuel Cycle Safety Research, Department of Environmental Safety Research and Department of Safety Research Technical Support in Tokai Research Establishment at JAERI. The Ad Hoc Review Committee consisted of 11 specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from December 2000 to February 2001. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on December 11, 2000, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on March 16, 2001. This report describes the result of the evaluation by the Ad Hoc Review Committee on Nuclear Safety Research. (author)

Preparation and HPLC isolation of L-[U-14C]tryptophan from enzyme hydrolysate labelled with 14C

International Nuclear Information System (INIS)

Novak, J.; Tintera, S.; Hromadkova, B.

1990-01-01

Tryptophan was obtained from biomass of the blue-green alga Synechococcus elongatus cultivated under 14 CO 2 . After partial purification, the protein fraction was subjected to enzymatic hydrolysis using pronase. Semipreparative isolation of L-[U- 14 C]tryptophan was accomplished on a HPLC column of Separon S Hema 1000 CM, 2% ethanol were added to the eluent, and a precolumn packed with the basic anion exchanger Spheron 1000 DEAE was used. Always after the passage of L-[U- 14 C]tryptophan, the precolumn was decoupled. The substance was collected in 96% ethanol. After removing the solvent by vacuum evaporation, the sample was analyzed on a column packed with Separon SIX C 18 in the eluent of 0.1M-NaH 2 PO 4 , 2% methanol. When the desired radiochemical purity was not attained, the sample was purified on Separon SIX C 18 using 2% methanol. The final radiochemical purity achieved by using this method is 98%. (P.A.). 5 figs., 2 tabs., 4 refs

Report of the first international workshop on human chromosome 14 mapping 1993

Energy Technology Data Exchange (ETDEWEB)

Cox, D.W.

1995-06-01

The first International Workshop on Human Chromosome 14 mapping was held at Novotel in Toronto, Canada on June 9-12, 1993. There were 23 participants from nine countries. The goals of the workshop were to compile physical maps and a consensus linkage map, to consolidate available data on disease loci, to catalogue and facilitate distribution of resources and to encourage new collaborations and data sharing.

Workshop on b-phenomenology, Edinburgh, UK, 8-14 December 1991

International Nuclear Information System (INIS)

Clarke, P.E.L.; Peach, K.J.; Richards, D.G.

1992-01-01

The frontier of understanding in heavy quark theory is moving fast. With the data emerging from LEP and from hadron facilities on heavy hadrons, and the developing interest in a custom-built B-factory, there is a need for detailed interaction among experimentalists and phenomenologically motivated theorists on the physics of b-quarks and B hadrons. To this end a workshop on heavy flavour physics was held at the University of Edinburgh from 8-14 December 1991. (Author)

Carbon-14 in the biosphere: Modeling and supporting research for the Canadian Nuclear Fuel Waste Management program

International Nuclear Information System (INIS)

Sheppard, S.C.; Amiro, B.D.; Sheppard, M.I.; Stephenson, M.; Zach, R.; Bird, G.A.

1994-01-01

Carbon-14 stands apart from most of the radionuclides present in nuclear fuel waste for several reasons. It has a relatively long radiological half-life and low retardation by granitic geological media so that 14 C is superceded only by 36 Cl and 129 I in potential release to the biosphere from unprocessed used fuel. In the biosphere, its importance continues because it is readily incorporated into the carbon compounds of life. Much of the behavior of 14 C in the biosphere can be conceptualized as isotopic exchange, where the 14 C mixes with 12 C from the biosphere. However, because of lack of data, the authors model the behavior of 14 C only partly as isotopic exchange, with most of the calculations relying on compartment transfer models. The authors experimental work has shown that soil-to-plant transfer may be dominated by the soil-atmosphere-plant pathway. Gaseous loss of 14 C from soils and lakes is significant. However, recalcitrant forms may persist in soils and sediments for long time periods. The impact of these forms is expected to be relatively low because their bioavailability is correspondingly low. Future research should be directed to support full modeling of 14 C as a series of isotopic exchange processes

Neurosurgical hand-held optical coherence tomography (OCT) forward-viewing probe

Science.gov (United States)

Sun, Cuiru; Lee, Kenneth K. C.; Vuong, Barry; Cusimano, Michael; Brukson, Alexander; Mariampillai, Adrian; Standish, Beau A.; Yang, Victor X. D.

2012-02-01

A prototype neurosurgical hand-held optical coherence tomography (OCT) imaging probe has been developed to provide micron resolution cross-sectional images of subsurface tissue during open surgery. This new ergonomic hand-held probe has been designed based on our group's previous work on electrostatically driven optical fibers. It has been packaged into a catheter probe in the familiar form factor of the clinically accepted Bayonet shaped neurosurgical non-imaging Doppler ultrasound probes. The optical design was optimized using ZEMAX simulation. Optical properties of the probe were tested to yield an ~20 um spot size, 5 mm working distance and a 3.5 mm field of view. The scan frequency can be increased or decreased by changing the applied voltage. Typically a scan frequency of less than 60Hz is chosen to keep the applied voltage to less than 2000V. The axial resolution of the probe was ~15 um (in air) as determined by the OCT system. A custom-triggering methodology has been developed to provide continuous stable imaging, which is crucial for clinical utility. Feasibility of this probe, in combination with a 1310 nm swept source OCT system was tested and images are presented to highlight the usefulness of such a forward viewing handheld OCT imaging probe. Knowledge gained from this research will lay the foundation for developing new OCT technologies for endovascular management of cerebral aneurysms and transsphenoidal neuroendoscopic treatment of pituitary tumors.

Behaviors of 14C-butachlor, 14C-chlorpyrifos and 14C-DDT in Rana japonica japonica Guenther

International Nuclear Information System (INIS)

Zhang Yiqiang; Zhong Chuangguang; Zhao Xiaokui; Chen Shunhua

2002-01-01

The research on the behaviors of 14 C-butachlor, 14 C-chlorpyrifos and 14 C-DDT in the frog Rana japonica japonica Guenther was carried out. After administrated per os to the frogs in doses of 380, 347, 363 Bq/g, 14 C-butachlor, 14 C-chlorpyrifos and 14 C-DDT, were distributed respectively to various organs within 24 h with specific accumulating organs as gallbladder, intestine and intestine, relevantly to the pesticides described. Compared to that in gallbladder and intestine, the radioactivity of many organs was extremely low, and this might due to the characters of the pesticides. Analysis of the metabolites of 14 C-DDT in frog at 24 th hr demonstrated that DDT was difficult to be degraded. Most 14 C-butachlor, 14 C-chlorpyrifos 14 C-DDT in liver and fat or ovary of frog was extractable with acetone. However, there were some differences between the pesticides, and the organs as well. And 14 C-butachlor, 14 C-chlorpyrifos or 14 C-DDT were better bound in liver than in fat

7 CFR 1209.18 - Region.

Science.gov (United States)

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Region. 1209.18 Section 1209.18 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION ORDER Mushroom Promotion, Research, and Consumer Information Order Definitions § 1209...

A perspective on tritium versus carbon-14: ensuring optimal label selection in pharmaceutical research and development.

Science.gov (United States)

Krauser, Joel A

2013-01-01

Tritium ((3) H) and carbon-14 ((14) C) labels applied in pharmaceutical research and development each offer their own distinctive advantages and disadvantages coupled with benefits and risks. The advantages of (3) H have a higher specific activity, shorter half-life that allows more manageable waste remediation, lower material costs, and often more direct synthetic routes. The advantages of (14) C offer certain analytical benefits and less potential for label loss. Although (3) H labels offer several advantages, they might be overlooked as a viable option because of the concerns about its drawbacks. A main drawback often challenged is metabolic liability. These drawbacks, in some cases, might be overstated leading to underutilization of a perfectly viable option. As a consequence, label selection may automatically default to (14) C, which is a more conservative approach. To challenge this '(14) C-by-default' approach, pharmaceutical agents with strategically selected (3) H-labeling positions based on non-labeled metabolism data have been successfully implemented and evaluated for (3) H loss. From in-house results, the long term success of projects clearly would benefit from a thorough, objective, and balanced assessment regarding label selection ((3) H or (14) C). This assessment should be based on available project information and scientific knowledge. Important considerations are project applicability (preclinical and clinical phases), synthetic feasibility, costs, and timelines. Copyright © 2013 John Wiley & Sons, Ltd.

Proceedings of the FNCA 2006 workshop on the utilization of research reactors (Contract research)

International Nuclear Information System (INIS)

2007-09-01

The FNCA 2006 Workshop on the Utilization of Research Reactors was held in Manila, Philippines from August 28 to September 1, 2006. This workshop was executed based on the agreement in the seventh Coordinator's Meeting of Forum for Nuclear Cooperation in Asia (FNCA) held in Tokyo, Mach 2006. The workshop consisted of three groups under the themes of the following fields; 1) Neutron Activation Analysis, 2) Research Reactor Technology and 3) Tc-99m Generator Technology. The total number of participants for the workshop was 45 people from 9 countries; China, Indonesia, Korea, Malaysia, the Philippines, Thailand, Vietnam, Bangladesh and Japan. This report consists of 10 papers for Neutron Activation Analysis, 7 papers for Tc-99m Generator Technology, 9 papers for Research Reactor Technology and a summary report. (author)

Proceedings of the FNCA 2003 workshop on the utilization of research reactors (Contract research)

International Nuclear Information System (INIS)

2006-03-01

The FNCA 2003 Workshop on the Utilization of Research Reactors, which is the twelfth workshop on the theme of research reactor utilization, was held in Dalat, Vietnam and Jakarta and Serpong, Indonesia from January 12 to 16, 2004. This workshop was executed based on the agreement in the fourth Coordinator's Meeting of Forum for Nuclear Cooperation in Asia (FNCA) held in Tokyo, March 2003. The workshop consisted of four groups under the theme of the following fields; 1) Neutron Activation Analysis, 2) Research Reactors, 3) Tc-99m Generator Technology and 4) Neutron Scattering. The total number of participants for the workshop was 93 people from 8 countries; China, Indonesia, Korea, Malaysia, the Philippines, Thailand, Vietnam and Japan. The 30 of the presented papers are indexed individually. (J.P.N.)

Ferroelectric Thin Films III, Symposium Held in San Francisco, California on April 13 - 16, 1993. Materials Research Society Symposium Proceedings, Volume 310

Science.gov (United States)

1993-04-16

Publication Data Ferroelectric thin films III : symposium held April 13-16, 1993, San Francisco,California, U.S.A. / editors, Bruce A. Turtle , Edwlrd R...All solutions were placed in a modified Collison Nebulizer which generated the droplets in an oxygen carrier gas. The droplets were transported into

[International Panel on 14 MeV Intense Neutron Source Based on Accelerators for Fusion Materials Study

International Nuclear Information System (INIS)

Thoms, K.R.; Wiffen, F.W.

1991-01-01

Both travelers were members of a nine-person US delegation that participated in an international workshop on accelerator-based 14 MeV neutron sources for fusion materials research hosted by the University of Tokyo. Presentations made at the workshop reviewed the technology developed by the FMIT Project, advances in accelerator technology, and proposed concepts for neutron sources. One traveler then participated in the initial meeting of the IEA Working Group on High Energy, High Flux Neutron Sources in which efforts were begun to evaluate and compare proposed neutron sources; the Fourth FFTF/MOTA Experimenters' Workshop which covered planning and coordination of the US-Japan collaboration using the FFTF reactor to irradiate fusion reactor materials; and held discussions with several JAERI personnel on the US-Japan collaboration on fusion reactor materials

Research Projects, Technical Reports and Publications

Science.gov (United States)

Oliger, Joseph

1996-01-01

The Research Institute for Advanced Computer Science (RIACS) was established by the Universities Space Research Association (USRA) at the NASA Ames Research Center (ARC) on June 6, 1983. RIACS is privately operated by USRA, a consortium of universities with research programs in the aerospace sciences, under contract with NASA. The primary mission of RIACS is to provide research and expertise in computer science and scientific computing to support the scientific missions of NASA ARC. The research carried out at RIACS must change its emphasis from year to year in response to NASA ARC's changing needs and technological opportunities. A flexible scientific staff is provided through a university faculty visitor program, a post doctoral program, and a student visitor program. Not only does this provide appropriate expertise but it also introduces scientists outside of NASA to NASA problems. A small group of core RIACS staff provides continuity and interacts with an ARC technical monitor and scientific advisory group to determine the RIACS mission. RIACS activities are reviewed and monitored by a USRA advisory council and ARC technical monitor. Research at RIACS is currently being done in the following areas: Advanced Methods for Scientific Computing High Performance Networks During this report pefiod Professor Antony Jameson of Princeton University, Professor Wei-Pai Tang of the University of Waterloo, Professor Marsha Berger of New York University, Professor Tony Chan of UCLA, Associate Professor David Zingg of University of Toronto, Canada and Assistant Professor Andrew Sohn of New Jersey Institute of Technology have been visiting RIACS. January 1, 1996 through September 30, 1996 RIACS had three staff scientists, four visiting scientists, one post-doctoral scientist, three consultants, two research associates and one research assistant. RIACS held a joint workshop with Code 1 29-30 July 1996. The workshop was held to discuss needs and opportunities in basic research in

47 CFR 32.6562 - Depreciation expense-property held for future telecommunications use.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Depreciation expense-property held for future... Expense Accounts § 32.6562 Depreciation expense—property held for future telecommunications use. This account shall include the depreciation expense of capitalized costs included in Account 2002, Property...

14 CFR 1207.102 - Waiver of prohibition in 18 U.S.C. 208.

Science.gov (United States)

2010-01-01

... Counsel; and (v) Procurement Officers. (2) For all other Headquarters employees, the Associate... Ethics. (e) Cross-references. For regulations concerning general waiver guidance and exemptions under 18...

Proceedings of the FNCA 2004 workshop on the utilization of research reactors (Contract research)

International Nuclear Information System (INIS)

2006-07-01

The FNCA 2004 Workshop on the Utilization of Research Reactors, which is the twelfth workshop on the theme of research reactor utilization, was held in Bangkok, Thailand from January 13 to 21, 2005. This workshop was executed based on the agreement in the fifth Coordinator's Meeting of Forum for Nuclear Cooperation in Asia (FNCA) held in Tokyo, March 2004. The workshop consisted of three groups under the themes of the following fields; 1) Neutron Activation Analysis, 2) Research Reactor Technology and 3) Tc-99m Generator Technology. The total number of participants for the workshop was 59 people from 8 countries; China, Indonesia, Korea, Malaysia, the Philippines, Thailand, Vietnam and Japan. This report consists of 6 papers for Neutron Activation Analysis, 5 papers for Research Reactor Technology, 5 Papers for Tc-99m Generator Technology and a summary report. The 15 of the presented papers are indexed individually. (J.P.N.)

F-14 in banked flight

Science.gov (United States)

1979-01-01

NASA 991, an F-14 Navy Tomcat designated the F-14 (1X), is seen here in banked flight over the desert on a research flight at NASA's Dryden Flight Research Center, Edwards, California. The F-14 was used at Dryden between 1979 and 1985 in extensive high-angle-of-attack and spin-control-and-recovery tests. The NASA/Navy program, which included 212 total flights, acheived considerable improvement in the F-14 high-angle-of-attack flying qualities, improved departure and spin resistance, and contributed to substantial improvements in reducing 'wing rock,' (i.e., tilting from one side to another), at high angles of attack. The Navy had been experiencing inadvertant spin entries caused by the F-14's aileron rudder interconnect. The NASA/Navy/Grumman team developed and tested 4 different configurations of the aileron rudder interconnect to address the spin problem. These problems prompted the Navy to ask the manufacturer, Grumman, and NASA to investigate the issue. NASA 991 had numerous special additions for high-angle-of-attack and spin-recovery research. These included a battery-powered auxiliary power unit, a flight test nose boom, and a special spin recovery system, consisting of forward mounted, hydraulically actuated canards and an emergency spin chute. NASA's F-14 was first flown by NASA research pilots, but was later flown by Grumman, and by Navy test pilots from Patuxent River Naval Air Station (NAS). The Navy test flights with the spin research vehicle constituted the first program that incorporated air combat maneuvering in its test flights at Dryden. The Navy brought F-14s from Point Mugu and Miramar NAS in San Diego to test the new spin control laws in combat situations. Although the new control laws proved valuable, the Navy did not incorporate them into production F-14s until the F-14D, nearly 15 years later.

14 CFR 385.18 - Authority of the Chief, Coordination Section, Documentary Services Division.

Science.gov (United States)

2010-01-01

... SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ORGANIZATION STAFF ASSIGNMENTS AND REVIEW OF ACTION UNDER ASSIGNMENTS Assignment of Functions to Staff Members § 385.18 Authority of the Chief...

Estimation of patient dose in 18 F-FDG and 18 F-FDOPA PET/CT examinations

Directory of Open Access Journals (Sweden)

Aruna Kaushik

2013-01-01

Full Text Available Purpose: To estimate specific organ and effective doses to patients resulting from the 18 F-FDG ( 18 F-2-deoxy-D-glucose and 18 F-FDOPA (6-fluoro-( 18 F-L-3, 4-dihydroxyphenylalanine PET/CT examinations for whole body and brain. Materials and Methods: Three protocols for whole body and three for brain PET/CT were used. The CTDI values were measured using standard head and body CT phantoms and also computed using a software CT-Expo for dose evaluation from the CT component. OLINDA software based on MIRD method was used for estimating doses from the PET component of the PET/CT examination. Results: The organ doses from 18 F-FDG and 18 F-FDOPA whole body and brain PET/CT studies were estimated. The total effective dose from a typical protocol of whole body PET/CT examination was 14.4 mSv for females and 11.8 mSv for male patients from 18 F-FDG, whereas it was 11 mSv for female and 9.1 mSv for male patients from 18 F-FDOPA. The total effective doses from a typical protocol for PET/CT studies of brain was 6.5 mSv for females and 5.1 mSv for males from 18 F-FDG whereas it was 3.7 mSv for females and 2.8 mSv for males from 18 F-FDOPA. Conclusions: The effective radiation doses from whole body PET/CT examination was approximately 4-8 times higher than the background radiation dose from both 18 F-FDG and 18 F-FDOPA scans, while it was 1-3 times the background radiation dose from PET/CT scans of brain.

Most promising research : research peer exchange, August 16-17, 2011.

Science.gov (United States)

2011-08-01

The Iowa Department of Transportation held a Research Peer Exchange on August 16-17, 2011 in Ames, Iowa. RAC members from Region 3 (Minnesota, Iowa, Missouri, Ohio) and the following states, Louisiana, Washington, Oregon, South Dakota, Arizona and Ut...

Report of the evaluation by the Ad Hoc Review Committee on High-Temperature Engineering and Research. Result evaluation in fiscal year 2000

International Nuclear Information System (INIS)

2001-06-01

The Research Evaluation Committee, which consisted of 14 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on High-Temperature Engineering and Research in accordance with the 'Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the R and D accomplishments achieved for five years from Fiscal Year 1995 to Fiscal Year 1999 at Department of HTTR Project and Department of Advanced Nuclear Heat Technology in Oarai Research Establishment of JAERI. The Ad Hoc Review Committee consisted of nine specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from December 2000 to February 2001. The evaluation was performed on the basis of the materials submitted in advanced and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on December 8, 2000, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on March 16, 2001. This report describes the result of the evaluation by the Ad Hoc Review Committee on High-Temperature Engineering and Research. (author)

Update of X- and γ-ray decay data standards for detector calibration and other applications. Summary report of the second research co-ordination meeting

International Nuclear Information System (INIS)

Herman, M.; Nichols, A.L.

2000-09-01

The Second Research Co-ordination Meeting to Update X- and γ-ray Decay Data Standards for Detector Calibration was held at PTB Braunschweig from 10 to 12 May 2000. A primary aim of this meeting was to review progress in the evaluation and recommendation of data under the auspices of the CRP. All CRP activities were reviewed, and actions agreed for the remaining 18 months of the programme. Separate indexing was provided for 13 contributions to the meeting

Update of X- and {gamma}-ray decay data standards for detector calibration and other applications. Summary report of the second research co-ordination meeting

Energy Technology Data Exchange (ETDEWEB)

Herman, M [International Atomic Energy Agency, Nuclear Data Section, Vienna (Austria); Nichols, A L [AEA Technology, Harwell (United Kingdom)

2000-09-01

The Second Research Co-ordination Meeting to Update X- and {gamma}-ray Decay Data Standards for Detector Calibration was held at PTB Braunschweig from 10 to 12 May 2000. A primary aim of this meeting was to review progress in the evaluation and recommendation of data under the auspices of the CRP. All CRP activities were reviewed, and actions agreed for the remaining 18 months of the programme. Separate indexing was provided for 13 contributions to the meeting.

A “dose on demand” Biomarker Generator for automated production of [18F]F− and [18F]FDG

International Nuclear Information System (INIS)

Awasthi, V.; Watson, J.; Gali, H.; Matlock, G.; McFarland, A.; Bailey, J.; Anzellotti, A.

2014-01-01

The University of Oklahoma—College of Pharmacy has installed the first Biomarker Generator (BG75) comprising a self-shielded 7.5-MeV proton beam positive ion cyclotron and an aseptic automated chemistry production and quality control module for production of [ 18 F]F − and clinical [ 18 F]FDG. Performance, reliability, and safety of the system for the production of “dose on demand” were tested over several months. No-carrier-added [ 18 F]F − was obtained through the 18 O(p,n) 18 F nuclear reaction by irradiation (20–40 min) of a >95% enriched [ 18 O]H 2 O target (280 μl) with a 7.5-MeV proton beam (3.5–5.0 μA). Automated quality control tests were performed on each dose. The HPLC-based analytical methods were validated against USP methods of quality control. [ 18 F]FDG produced by BG75 was tested in a mouse tumor model implanted with H441 human lung adenocarcinoma cells. After initial installment and optimization, the [ 18 F]F − production has been consistent since March 2011 with a maximum production of 400 to 450 mCi in a day. The average yield is 0.61 mCi/min and 0.92 mCi/min at 3.8 µA and 5 µA, respectively. The current target window has held up for over 25 weeks against >400 bombardment cycles. [ 18 F]FDG production has been consistent since June 2012 with an average of six doses/day in an automated synthesis mode (RCY≈50%). The release criteria included USP-specified limits for pH, residual solvents (acetonitrile/ethanol), kryptofix, radiochemical purity/identity, and filter integrity test. The entire automated operation generated minimal radiation exposure hazard to the operator and environment. As expected, [ 18 F]FDG produced by BG75 was found to delineate tumor volume in a mouse model of xenograft tumor. In summary, production and quality control of “[ 18 F]FDG dose on demand” have been accomplished in an automated and safe manner by the first Biomarker Generator. The implementation of a cGMP quality system is under way towards

Speciation analysis of arsenic, chromium and selenium in aquatic media. Proceedings of a final research coordination meeting

International Nuclear Information System (INIS)

2007-03-01

The initiation of the Coordinated Research Project (CRP) on Development and Validation of Speciation Analysis using Nuclear Techniques resulted from the recognition that knowledge of total element concentration does not provide adequate information to understand the effects of trace and heavy metals observed in the environment and in living systems. Their toxicity, bioavailability, physiological and metabolic processes, mobility and distribution are greatly dependent on the specific chemical form of the element. Speciation analysis has yet to be developed to its full potential for biochemical, clinical and environmental investigations and still more work is needed in the near future. Seven participants from seven countries participated in this CRP covering a range of analytical techniques including GC, HPLC, AAS, and ICP-MS. The first Research Coordination Meeting (RCM) of the Coordinated Research Project on the Development and Validation of Speciation Analysis using Nuclear Techniques was held at the Reactor Centre of the Jozef Stefan Institute, Podgorica (near Ljubljana), Slovenia, 20-23 June 2001. The second RCM was held at the Technical University of Vienna, 18-22 November 2002, where, in addition to the participants, two external researchers could present their views and experience in the field. The last RCM was held in Vienna, 26-29 April 2004, and this publication is a summary of the results achieved and presented at this last RCM. The participants have developed several new procedures for the reliable analysis of As, Cr, and Se species, mainly in aquatic media. A new instrument was designed and several recommendations for speciation analysis were issued. It is hoped that this publication will make a contribution to enhancing the awareness of the importance of speciation analysis and add to the reliability of speciation results in Member State laboratories

ESTUDIO DE INVESTIGACIÓN SOBRE LAS NUEVAS PAUTAS DE CONSUMO DE ALCOHOL Y DROGAS EN JÓVENES ADOLESCENTES (14-18 AÑOS) EN ANDALUCÍA

OpenAIRE

Jódar-Matey, María del Valle

2013-01-01

El presente trabajo de investigación tiene la intención de realizar un breve recorrido de lo que supone el uso de sustancias adictivas en la franja de edad conocida como adolescencia (14-18 años), por la especial vulnerabilidad que presenta este grupo de población. Las nuevas formas familiares, las fluctuaciones económicas y las nuevas tecnologías juegan un papel definitorio a la hora de conformar nuevas pautas en el acceso, consumo y/o adicciones de drogas y alcohol. Los ad...

Rapid and automatic chemical identification of the medicinal flower buds of Lonicera plants by the benchtop and hand-held Fourier transform infrared spectroscopy

Science.gov (United States)

Chen, Jianbo; Guo, Baolin; Yan, Rui; Sun, Suqin; Zhou, Qun

2017-07-01

With the utilization of the hand-held equipment, Fourier transform infrared (FT-IR) spectroscopy is a promising analytical technique to minimize the time cost for the chemical identification of herbal materials. This research examines the feasibility of the hand-held FT-IR spectrometer for the on-site testing of herbal materials, using Lonicerae Japonicae Flos (LJF) and Lonicerae Flos (LF) as examples. Correlation-based linear discriminant models for LJF and LF are established based on the benchtop and hand-held FT-IR instruments. The benchtop FT-IR models can exactly recognize all articles of LJF and LF. Although a few LF articles are misjudged at the sub-class level, the hand-held FT-IR models are able to exactly discriminate LJF and LF. As a direct and label-free analytical technique, FT-IR spectroscopy has great potential in the rapid and automatic chemical identification of herbal materials either in laboratories or in fields. This is helpful to prevent the spread and use of adulterated herbal materials in time.

Improvement of basic food crops in Africa through plant breeding, including the use of induced mutations. Report of the third research co-ordination meeting of FAO/IAEA/ITALY co-ordinated research programme. Working material

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-12-01

A Co-ordinated Research Programme, on ``Improvement of basic food corps in Africa through plant breeding including the use of induced mutations``, funded by the Italian Governmnet, was initiated in the Joint Division of the Food and Agriculture Organization and International Atomic Energy Agency, Vienna. The primary objective of this CRP was to breed improved varieties of staple food crops of Africa with main emphasis on the indigenous species and local cultivars. The Third Research Co-ordination Meeting (RCM) under the FAO/IAEA/ITALY Co-ordinated Research Programme was held in Nairobi, Kenya, 20-24 September 1993 in which 24 persons participated and 18 scientific reports were presented. These included reports from 10 Research Contract holders from Africa, 3 Technical Contract holders from Italy and the update on the backstopping of research carried out at the IAEA Laboratories, Seibersdorf. The reports, and conclusions and recommendations made by the participants are presented in this publication. Refs, figs, tabs.

Improvement of basic food crops in Africa through plant breeding, including the use of induced mutations. Report of the third research co-ordination meeting of FAO/IAEA/ITALY co-ordinated research programme. Working material

International Nuclear Information System (INIS)

1997-01-01

A Co-ordinated Research Programme, on ''Improvement of basic food corps in Africa through plant breeding including the use of induced mutations'', funded by the Italian Governmnet, was initiated in the Joint Division of the Food and Agriculture Organization and International Atomic Energy Agency, Vienna. The primary objective of this CRP was to breed improved varieties of staple food crops of Africa with main emphasis on the indigenous species and local cultivars. The Third Research Co-ordination Meeting (RCM) under the FAO/IAEA/ITALY Co-ordinated Research Programme was held in Nairobi, Kenya, 20-24 September 1993 in which 24 persons participated and 18 scientific reports were presented. These included reports from 10 Research Contract holders from Africa, 3 Technical Contract holders from Italy and the update on the backstopping of research carried out at the IAEA Laboratories, Seibersdorf. The reports, and conclusions and recommendations made by the participants are presented in this publication. Refs, figs, tabs

Highlights of the 2012 research workshop: Using nutrigenomics and metabolomics in clinical nutrition research

Science.gov (United States)

The American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) Research Workshop, "Using Nutrigenomics and Metabolomics in Clinical Nutrition Research," was held on January 21, 2012, in Orlando, Florida. The conference brought together experts in human nutrition who use nutrigenomic and meta...

A hand-held 3D laser scanning with global positioning system of subvoxel precision

International Nuclear Information System (INIS)

Arias, Nestor; Meneses, Nestor; Meneses, Jaime; Gharbi, Tijani

2011-01-01

In this paper we propose a hand-held 3D laser scanner composed of an optical head device to extract 3D local surface information and a stereo vision system with subvoxel precision to measure the position and orientation of the 3D optical head. The optical head is manually scanned over the surface object by the operator. The orientation and position of the 3D optical head is determined by a phase-sensitive method using a 2D regular intensity pattern. This phase reference pattern is rigidly fixed to the optical head and allows their 3D location with subvoxel precision in the observation field of the stereo vision system. The 3D resolution achieved by the stereo vision system is about 33 microns at 1.8 m with an observation field of 60cm x 60cm.

Transformation research for a sustainable energy system. Contributions; Transformationsforschung fuer ein nachhaltiges Energiesystem. Beitraege

Energy Technology Data Exchange (ETDEWEB)

Stadermann, Gerd; Szczepanski, Petra; Wunschick, Franziska; Martin, Niklas (comps.)

2012-03-15

Within the 2011 annual meeting of the Renewable Energy Research Association (Berlin, Federal Republic of Germany) from 12th to 13th October 2011, the following lectures were held: (1) Environmentally safe and socially compatible transformation of energy systems (G. Schuette); (2) Open questions on the transformation of energy systems (E. Weber); (3) System analysis on the transformation of energy systems up to 2050 (J. Schmid); (4) Economic aspects: Chances, markets and workplaces (F. Staiss); (5) Perspectives for an interplay of energy efficiency and renewable energy resources as well as their implementation in the energy system (A. Bett); (6) New accents of research promotion for a more rapid development of renewable energy sources (K. Deller); (7) The 6th Energy Research Program of the Federal Government (R. Tryfonidou); (8) Recommendations of the FVEE for the research policy of the Research Government (G. Sadermann); (9) How can research and politics promote the system transformation (M. Hustedt); (10) The energy system of tomorrow - Strategies and research for the transformation of high amounts of renewable energy resources (W. Duerrschmidt); (11) Long-term strategies for the development of renewable energies in Germany (J. Nitsch); (12) Development of storage capacities for an efficient power generation by renewable energy resources in Germany and Europe by 2050 (Y. Scholz); (13) Prognoses of temporal and spatial variability of renewable energy resources (B. Lange); (14) Smart Grids - Transformation of our electrical energy supply (G. Ebert); (15) Model regions for intelligently networked energy systems; (16) Cities and concepts of neighbourhood - model cities (D. Schmidt); (17) Transformation of the German power system to a decentral regenerative economy (U. Leprich); (18) Alteration of the general conditions for new incentive models, heat acts, restoration of buildings (M. Schmidt); (19) Acceptance and participation research on energy sustainability (P

Giessen international workshop on interactions of exocrine and endocrine pancreatic diseases. Castle of Rauischholzhausen of the Justus-Liebig-University, Giessen, Germany. March 18-19, 2005.

Science.gov (United States)

Andren-Sandberg, Ake; Hardt, Philip D

2005-07-08

The 'Giessen International Workshop on Interactions of Exocrine and Endocrine Pancreatic Diseases' was held on March 18-19, 2005 at the Castle of Rauischolzhausen, Giessen University, Germany. About 50 international clinicians and researchers attended the workshop. It was structured into three sessions: A: Pancreatic Autoimmunity - Interaction Between Exocrine and Endocrine Tissue; B: Diabetes Mellitus - Possible Implications of Exocrine Pancreatic Insufficiency; C: Chronic Pancreatitis - Update on Prevalence, Understanding and Pathophysiological Concepts. Several new aspects of pancreatic diseases were discussed, including new classifications of pancreatitis, new insights into prevalence, pathophysiology and new therapeutical considerations. The meeting resulted in more cooperation and a number of new concepts for clinical study which will provide data for future developments.

29 CFR 453.21 - Interests held in agents, brokers, and surety companies.

Science.gov (United States)

2010-07-01

... 29 Labor 2 2010-07-01 2010-07-01 false Interests held in agents, brokers, and surety companies... LABOR-MANAGEMENT REPORTING AND DISCLOSURE ACT OF 1959 Qualified Agents, Brokers, and Surety Companies for the Placing of Bonds § 453.21 Interests held in agents, brokers, and surety companies. (a) Section...

Mise-a-la-masse measurements in drillholes OL-KR4, OL-KR30 and OL-KR14 - OL-KR18 in Olkiluoto

International Nuclear Information System (INIS)

Kristiansson, S.; Heikkinen, P.

2009-02-01

Mise-a-la-masse measurements were conducted in the Olkiluoto investigation site in the time period from May to November 2007. Measurements were carried out in drillholes OL-KR4, OL-KR30 and OL-KR14 - OL-KR18. The purpose of the study was to collect data for geological modelling. The aim is to evaluate the continuity of fractures and other geological structures from a drillhole to another drillhole and from a drillhole to the ground surface. Posiva has developed electrodes for mise-a-la-masse method measurements, where the location of the electrode is between rubber disks similar to the flow guide. Rubber disks prevent leakage of current along the drillhole and focus current directly to a specific fracture. (orig.)

Co-ordinated research programme on assessment of environmental exposure to mercury in selected human populations as studied by nuclear and other techniques. Report on the second research co-ordination meeting held in Kuala Lumpur, Malaysia, 24-28 August 1992

International Nuclear Information System (INIS)

1992-01-01

A Coordinated Research Programme (CRP) on assessment of environmental exposure to mercury in selected human populations as studied by nuclear and other techniques was initiated by the IAEA in 1990 in collaboration with WHO. The purpose of this CRP is to promote national and regional studies to evaluate the exposure of selected population groups to mercury and methylmercury and to estimate potential health risks in these groups. The programme is focused on the analysis of human head hair for the determination of mercury and methylmercury. This CRP has two main components: (i) identifying population groups that are at risk, and (ii) studying health effects in the exposed persons, particularly pregnant women and the babies born to them. This report contains the discussions held during the second Research Co-ordination Meeting (RCM) for the CRP which took place in Kuala Lumpur, Malaysia, under the sponsorship of the University Kebangsaan Malaysia and papers presented at this meeting. Refs, figs and tabs

Studies in Teaching: 2017 Research Digest. Action Research Projects Presented at Annual Research Forum (Winston-Salem, North Carolina, June 29, 2017)

Science.gov (United States)

McCoy, Leah P., Ed.

2017-01-01

This document presents the proceedings of the 22nd Annual Research Forum held June 29, 2017, at Wake Forest University in Winston-Salem, North Carolina. Included are the following 12 action research papers: (1) Using Captioned Video to Teach Listening Comprehension in a Spanish Classroom (Michelle Allen); (2) Multimodal Instruction: How Film…

Research on the relationship between humans and wilderness in Alaska

Science.gov (United States)

Alan E. Watson

2005-01-01

At the 2005 Biennial George Wright Society Conference on Parks, Protected Areas, and Cultural Sites in Philadelphia, March 14 to 18, there were many sessions relevant to wilderness. One session provided focus on a priority research area of the Leopold Institute: understanding the effects of management actions on relationships between people and wilderness. A great...

The participation of minors in preventive HIV research trials in South Africa: legal and human rights considerations.

Science.gov (United States)

van Wyk, Christa

2003-01-01

The constitutional prohibition of experimentation/research without the individual subject's (own) consent is investigated. A distinction is drawn between therapeutic and non-therapeutic research. A minor of 14 is competent to consent independently to medical treatment (which would include therapeutic research), but not to non-therapeutic research. A minor must be at least 18 years to be able to do so. Proxy consent can be secured for the participation of minors under 18 in non-therapeutic research only if they assent, if their participation in the research is indispensable and the research carries no more than negligible risk. Since the risks inherent in HIV preventive vaccine trials may carry more than negligible risk, these trials may not be carried out on children under 18. The limitation of rights and the consideration of foreign and international law in the interpretation of the South African Bill of Rights are investigated.

Proceedings of the 6th symposium on advanced photon research

International Nuclear Information System (INIS)

2005-06-01

The 6th Symposium on Advanced Photon Research was held at JAERI-Kansai in Kyoto on November 4-5, 2004. The symposium has been held once a year since 1999, to promote the advanced photon research through speeches, information exchanges, discussion by researchers on the front line of advanced photon research in Japan and abroad, not only reports of latest research results and plans at Advanced Photon Research Center. The numbers of speeches were 16, including 5 invited speeches, and the numbers of poster presentations were 56, including the report of presentations and cooperative research and joint research performed in FY2003. The 56 of the presented papers are indexed individually. (J.P.N.)

Report of researches by joint use of Kyoto University Research Reactor Institute in the second half of the fiscal year 1978

International Nuclear Information System (INIS)

1981-03-01

This is the biannual report of 69 research items by the joint use of the reactor, each item being written in a page. The research items are roughly classified into 25 items related to chemistry, 18 items to physics, 6 items to metallurgy, 4 items to geology, 14 items to biology and medicine, and 2 items to agriculture. Presence of many items related to physics and chemistry is a matter of course, but the increase of the items related to biology and medicine is noticeable. (Wakatsuki, Y.)

Proceedings of the 18th technical meeting on nuclear reactor and radiation for KURRI engineers and the 9th technical official group section 5 meeting in Kyoto University

International Nuclear Information System (INIS)

2010-03-01

This report is a summary of 18th Technical Meeting on Nuclear Reactor and Radiation for KURRI Engineers in Kyoto University. This was also the 9th meeting for technical official group section 5 (nuclear and radiation) in Kyoto University. In the workshop, three special lectures held were: (1) 'On Border Between Subcritical and Supercritical', (2) 'Memories of Nuclear Power Plant Management for 40 Years', and (3) 'Introduction of Technical Office in Faculty of Engineering, Kyoto University'. The technical presentations held were: (1) 'Radiation Background Study of Specialty Products in Senshu Region', (2) 'Introduction of Radioactivation Analysis at KUR', (3) 'Consideration of Critical Approach Method for KUR Low-Enrichment Fuel Reactor Core Using SRAC', (4) 'Evaluation of Temperature Coefficient of KUR Low-Enrichment Fuel Reactor Core Using SRAC'. As training for technical staffs in Technical Office, we visited the facility in Ashiu Research Forest. An introduction of this facility and the comments from the participants were included in this report. (S.K.)

Proceedings of the International Association for Development of the Information Society (IADIS) International Conference on Cognition and Exploratory Learning in Digital Age (14th, Vilamoura, Algarve, Portugal, October 18-20, 2017)

Science.gov (United States)

Sampson, Demetrios G., Ed.; Spector, J. Michael, Ed.; Ifenthaler, Dirk, Ed.; Isaías, Pedro, Ed.

2017-01-01

These proceedings contain the papers of the 14th International Conference on Cognition and Exploratory Learning in the Digital Age (CELDA 2017), 18-20 October 2017, which has been organized by the International Association for Development of the Information Society (IADIS) and endorsed by the Japanese Society for Information and Systems in…

What we do | Page 18 | IDRC - International Development Research ...

International Development Research Centre (IDRC) Digital Library (Canada)

... people living in poverty in the rural-urban territories of Chile, Colombia, and Mexico. ... Improving Food and Nutrition Security in the Philippines through School ... an estimated 14 percent of school children experience severe malnutrition.

French women’s knowledge of and attitudes towards cervical cancer prevention and the acceptability of HPV vaccination among those with 14 – 18 year old daughters: a quantitative-qualitative study

Directory of Open Access Journals (Sweden)

Haesebaert Julie

2012-11-01

Full Text Available Abstract Background In France, it is recommended that girls and women aged 14–23 are vaccinated against the human papillomavirus (HPV. However, French women’s knowledge of and attitude towards the vaccine has been little studied. Methods Thirty-nine general practitioners, representative of those working in the large Rhône-Alpes region, offered a self-administered questionnaire on cervical cancer (CC prevention to all 18–65 year-old women who came for consultation during June and July 2008. In addition, semi-structured interviews were undertaken with a sample of those who had daughters aged 14–18. Results Of the 1,478 women who completed the questionnaire, only 16.9% mentioned HPV as the cause of CC, even though 76.2% knew of the vaccine. 210 women had daughters aged 14–18, and 32 were interviewed. Compared with the wider group, more of these women were aware of the HPV vaccine (91.4%. 44.8% knew the target population and 17.1% the recommended ages for vaccination. 54.3% favoured HPV vaccination; 37.2% were undecided and only 0.9% were opposed. The main barrier to acceptance was the recency of the vaccine’s introduction and concern about possible side effects (54.9%; 14.1% preferred to rely on their GP’s decision. Factors associated with acceptance of the HPV vaccine were having previously vaccinated a child against pneumococcus (OR=3.28 [1.32-8.11] and knowing the target population for HPV vaccination (OR=2.12 [1.15-3.90]. Knowing the recommended frequency of Papanicolaou smear testing (Pap test screening was associated with lower acceptance (OR=0.32 [0.13-0.82]. Conclusions Few mothers are opposed to HPV vaccination. Factors associated with acceptability were knowledge about the vaccine, acceptance of other vaccines and, unexpectedly, lack of knowledge about the recommended frequency of Pap testing. On multivariate analysis, compliance with recommendations for Pap test screening and socioeconomic factors had no effect on views

Inventory of Dutch National Research on Global Climate Change: Inside and outside the National Research Programme

International Nuclear Information System (INIS)

Smythe, K.D.; Bernabo, C.; Kingma, J.; Vrakking, W.

1993-04-01

This summary of Dutch research on global climate change was compiled from a survey of the major research organisations in the Netherlands. The scope and structure of the survey and this report were based on a request for information from the World Meteorological Organisation for an intergovernmental meeting on the World Climate Programme (WCP) held (from 14 to 16 April 1993). The WMO request emphasized activities related to the WCP and its associated programmes. To extend the usefulness of the exercise, an attempt has been made to broaden the focus to give additional attention to the Intergovernmental Geosphere-Biosphere Programme (IGBP) and the Human Dimensions Programme (HDP). This was the first attempt to inventory the research projects on global climate change underway in the Netherlands - both inside and outside the National Research Programme. Other surveys on Dutch climate-related research have been conducted. The most extensive effort was a cataloging of publications from climate research in the Netherlands from 1981 to 1991, which was conducted by the Netherlands Royal Academy of Sciences (KNAW). That inventory is being updated to include publications through 1992. The database resulting from this exercise will be a useful tool for organisations sponsoring and conducting global climate change research in their efforts to stimulate cooperation and promote coordination among research groups in the Netherlands and abroad. There are plans to update the inventory in the future and to provide the information to participating Dutch organisations as well as research organisations in other countries. An overview of the current research is provided in Volume 1 with a list of projects

Synthesis and Preliminary Evaluation of 5-[18F]fluoroleucine.

Science.gov (United States)

Chin, Bennett B; McDougald, Darryl; Weitzel, Douglas H; Hawk, Thomas; Reiman, Robert E; Zalutsky, Michael R; Vaidyanathan, Ganesan

2017-01-01

Amino acid transporters, such as LAT1, are overexpressed in aggressive prostate and breast carcinomas, directly influencing pathways of growth and proliferation. The purpose of this study was to synthesize and characterize a novel 18F labeled leucine analog, 5-[18F]fluoroleucine, as a potential imaging agent for aggressive tumors which may not be amenable to imaging by FDG PET. 5-fluoroleucine was synthesized and characterized, and its 18F-labeled analog was synthesized from a mesylate precursor. First, breast cancer cell line assays were performed to evaluate uptake of 3H- or 14C-labeled L-leucine and other essential amino acids. Both L-leucine and 5- [18F]fluoroleucine were tested for uptake and accumulation over time, and for uptake via LAT1. Biodistribution studies were performed to estimate radiation dosimetry for human studies. Small animal PET / CT studies of a breast cancer were performed to evaluate in vivo 5-[18F]fluoroleucine tumor uptake. Breast cancer cell lines showed increasing high net accumulation of L-[14C]leucine. Both L-leucine and 5-[18F]fluoroleucine showed increasing uptake over time in in vitro tumor cell assays, and uptake was also shown to occur via LAT1. The biodistribution study of 5-[18F]fluoroleucine showed rapid renal excretion, no significant in vivo metabolism, and acceptable dosimetry for use in humans. In vivo small animal PET / CT imaging of a breast cancer xenograft showed uptake of 5- [18F]fluoroleucine in the tumor, which progressively increased over time. 5-[18F]fluoroleucine is a leucine analog which may be useful in identifying tumors with high or upregulated expression of amino acid transporters, providing additional information that may not be provided by FDG PET. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Examining the Personal Nature of the K-14 Engineering Pipeline for Young Women

Science.gov (United States)

Gurski, Jennifer Sue

This mixed-methods study examined young women's perceptions of their K-14 STEM pipeline experiences and their resulting choice to enter and persist in an engineering major. Despite the increase of women in the STEM workforce, women remain underrepresented among engineering majors (Beasley & Fischer, 2012; Heilbronner, 2012; Neihart & Teo, 2013). Few studies exist that utilize a retrospective approach to understand how the culmination of young women's K-14 experiences have influenced their formation of individually held perceptions that lead to engineering persistence. It is this study's aim to utilize a mixed-methods approach to answer the following research question: How do young women's perceptions of their K-14 STEM experiences influence their decision to enroll and persist in an engineering major? These perceptions are explored through an ethnographic approach focusing on young women enrolled in engineering programs during their junior and senior years of study at a small private liberal arts university with eight engineering majors. The mixed-methods approach follows a sequential design method (Creswell, 2013) and utilizes questions in a quantitative Likert-type survey from the Academic Pathways for People Learning Engineering (APPLES) survey (Eris, Chachra, Chen, Sheppard, & Ludlow, 2010) and the Motivated Strategy Learning Questionnaire (MSLQ) (Pintrich, Smith, Garcia, & McKeachie, 1991). The quantitative study results will lead to the development of open-ended, structured questions for conducting a qualitative focus group. Anonymity of all participants is maintained. Keywords: STEM, young women, perceptions, pipeline, intervention, underrepresentation, engineering, persistence, retrospective, self-efficacy.

Portable Hand-Held Electrochemical Sensor for the Transuranics

Energy Technology Data Exchange (ETDEWEB)

Dale D. Russell, William B. Knowlton, Ph.D.; Russel Hertzog, Ph.D

2005-11-25

sensitive detector for uranium. Millimeter scale electrodes, operated by a hand-held instrument assembled in this lab and operated in the voltammetric mode, were transported to the DOE-Nevada test site (Las Vegas, NV) where field detection and quantitation of plutonium, uranium, and a mixture of these two elements was also demonstrated. Several probe designs were prepared, built and tested including probes with movable protective windows. A miniature, battery powered potentiostat was designed, built and demonstrated for use in a hand-held field portable instrument. This work was performed largely by undergraduates who gained valuable research experience, and many of them have continued on to graduate schools. In addition, they all gained exposure to and appreciation for national security research, in particular non-proliferation research. Four graduate students participated and one earned the MS degree on this project.

Prospects and future utilization. Proceedings of a colloquium held in Petten (Netherlands), 20-21 April 1989

International Nuclear Information System (INIS)

Ahlf, J.; Roettger, H.

1989-01-01

These proceedings of a colloquium held in Petten on prospects and future utilization of the HFR reactor are divided into 6 sessions bearing on: - The high flux reactor - irradiation testing of fuel and material for fast breeder reactors - irradiation testing of fuel and material for high temperature reactors and light water reactors - irradiation testing for fusion reactors - neutron radiography, radioisotopes, neutron capture therapy - neutron beam research and application of neutron activation analysis

Identifying future research directions for biodiversity, ecosystem services and sustainability : perspectives from early-career researchers

NARCIS (Netherlands)

Hossain, S.; Pogue, S.J.; Trenchard, L.; Oudenhoven, van A.P.E.; Washbourne, C-L.; Muiruri, E.W.; Tomczyk, A.M.; García-Llorente, M.; Hale, R.; Hevia, V.; Adams, T.; Tavallali, L.; De, Bell S.; Pye, M.; Resende, F.

2017-01-01

We aimed to identify priority research questions in the field of biodiversity, ecosystem services and sustainability (BESS), based on a workshop held during the NRG BESS Conference for Early Career Researchers on BESS, and to compare these to existing horizon scanning exercises. This work highlights

Report on the SNL/NSF International Workshop on Joint Mechanics, Arlington, Virginia, 16-18 October 2006.

Energy Technology Data Exchange (ETDEWEB)

Ewins, David J. (Imperial College, London England, UK); Bergman, Lawrence A. (University of Illinois, Urbana, IL); Segalman, Daniel Joseph

2007-11-01

The NSF/SNL joint mechanics workshop, held in Arlington, Virginia, 16-18 October, 2006, attempted to assess the current state of the art for modeling joint mechanics for the purpose of structural dynamics calculation, to identify the underlying physics issues that must be addressed to advance the field, and to propose a path forward. Distinguished participants from several countries representing research communities that focus on very different length and time scales identified multiple challenges in bridging those scales. Additionally, two complementary points of view were developed for addressing those challenges. The first approach - the 'bottom-up' perspective - attempts to bridge scales by starting from the smallest length scale and working up. The other approach starts at the length scale of application and attempts to deduce mechanics at smaller length scales through reconciliation with laboratory observation. Because interface physics is a limiting element of predictive simulation in defense and transportation, this issue will be of continuing importance for the foreseeable future.

Studies in Teaching: 2016 Research Digest. Action Research Projects Presented at Annual Research Forum (Winston-Salem, North Carolina, Jun 30, 2016)

Science.gov (United States)

McCoy, Leah P., Ed.

2016-01-01

This document presents the proceedings of the 21st Annual Research Forum held June 30, 2016, at Wake Forest University in Winston-Salem, North Carolina. Included are the following 11 action research papers: The Use of Mexican Folk Art to Develop Oral and Written Language Ability and Cultural Awareness in the Secondary Spanish Classroom (Antonio…

Mapping of functional activity in brain with 18F-fluoro-deoxyglucose

International Nuclear Information System (INIS)

Alavi, A.; Reivich, M.; Greenberg, J.; Wolf, A.

1981-01-01

A model has been designed based on the assumptions of a steady state for glucose consumption, a first-order equilibration of the free 14 C-DG pool in the tissue with the plasma level, and relative rates of phosphorylation of 14 C-DG and glucose determined by their kinetic constants for hexokinase reaction. Using an operational equation based on this model, the metabolic rates of glucose are calculated in various regions of brain (utilizing brain slices and autoradiography). 14 C is a beta emitter and therefore not suitable for noninvasive imaging in man. With the synthesis of 18 F-2-deoxy-2-fluoro-D-glucose ( 18 F-DG) all of the requirements for a suitable radiopharmaceutical for the determination of local cerebral metabolism have been met. This agent behaves very similarly to 14 C-DG and therefore, using the above described model and emission tomography, it has become possible to measure regional cerebral metabolism for the first time in man

Nanoscience Research for Energy Needs. Report of the National Nanotechnology Initiative Grand Challenge Workshop, March 16-18, 2004

Energy Technology Data Exchange (ETDEWEB)

Alivisatos, P.; Cummings, P.; De Yoreo, J.; Fichthorn, K.; Gates, B.; Hwang, R.; Lowndes, D.; Majumdar, A.; Makowski, L.; Michalske, T.; Misewich, J.; Murray, C.; Sibener, S.; Teague, C.; Williams, E.

2004-03-18

This document is the report of a workshop held under NSET auspices in March 2004 aimed at identifying and articulating the relationship of nanoscale science and technology to the Nation's energy future.

Contributions of the Nuclear Research Institute to the French-Czechoslovak seminar on the management of radioactive wastes held on 12-14 May, 1987

International Nuclear Information System (INIS)

1987-01-01

Paper were submitted on the use of calcination in liquid radioactive waste solidification; experience with the operation of mobile lines of the MESA type which are tested at nuclear power plants; the treatment of low level liquid wastes from special laundries. Other papers described experience with the operation of the facility for processing low and intermediate level wastes run by UJV (Nuclear Research Institute) since 1962, and the conditions for a radioactive waste burial site in Czechoslovakia. (E.S.). 3 tabs

Epilepsy Forewarning Using A Hand-Held Device

Energy Technology Data Exchange (ETDEWEB)

Hively, LM

2005-02-21

Over the last decade, ORNL has developed and patented a novel approach for forewarning of a large variety of machine and biomedical events. The present implementation uses desktop computers to analyze archival data. This report describes the next logical step in this effort, namely use of a hand-held device for the analysis.

Plans for Hand-Held/Portable Oil Assessment Devices

National Research Council Canada - National Science Library

Urbansky, Edward

2005-01-01

At the request of the U.S. Army Oil Analysis Program, the JOAP TSC conducted a market study, assembled a plan of action, and prepared a worksheet for the evaluation of portable or hand-held oil assessment devices...

From Research Assistant to Professional Research Assistance: Research Consulting as a Form of Research Practice

Directory of Open Access Journals (Sweden)

Dawn E. Pollon

2013-01-01

Full Text Available Research assistantships have long been viewed as an extension of the formal education process, a form of apprenticeship, and a pathway into the professional practice of research in institutional settings. However, there are other contexts in which researchers practice research. This self-study documents the formative role research assistantships played in the authors’ development as professional research consultants. Four professional research consultants who held research assistant positions during their master’s and doctoral studies describe the contributions of their research assistantship experiences to the advancement of their knowledge, skills, and passion for research and subsequently to their career decisions. Professional research consulting is identified as a natural extension of research assistant roles and a potential career path. The article enhances current understandings about the ways research assistantships contribute to the development of researchers, and specifically to the development of professional research consultants. The analysis will be of interest to students contemplating entering into research assistantships, current research assistants, current research assistant supervisors, academic staff looking to improve their research productivity, and department chairs.

Adipose tissue interleukin-18 mRNA and plasma interleukin-18: effect of obesity and exercise

DEFF Research Database (Denmark)

Leick, Lotte; Lindegaard, Birgitte; Stensvold, Dorthe

2007-01-01

resistance was tested. Furthermore, we speculated that acute exercise and exercise training would regulate AT IL-18 mRNA expression. RESEARCH METHODS AND PROCEDURES: Non-obese subjects with BMI women: n = 18; men; n = 11) and obese subjects with BMI >30 kg/m(2) (women: n = 6; men: n = 7...... of regular physical activity with improved insulin sensitivity.......OBJECTIVES: Obesity and a physically inactive lifestyle are associated with increased risk of developing insulin resistance. The hypothesis that obesity is associated with increased adipose tissue (AT) interleukin (IL)-18 mRNA expression and that AT IL-18 mRNA expression is related to insulin...

Evaluation of a mid-career investigator career development award: Assessing the ability of OppNet K18 awardees to obtain NIH follow-on research funding.

Science.gov (United States)

Pomeroy-Carter, Cassidy A; Williams, Sharon R; Han, Xueying; Elwood, William N; Zuckerman, Brian L

2018-01-01

The National Institutes of Health (NIH) K18 award mechanism provides funded opportunities for established investigators to gain knowledge in fields outside of their primary disciplines, but outcomes associated with these awards have not been evaluated to date. NIH's Basic Behavioral and Social Sciences Opportunity Network (OppNet) is one of the few initiatives that has used this award mechanism. We explored how the unique features of K18 awards affect the ability of recipients to obtain follow-on NIH research funding. We compared outcomes (ability to obtain follow-on funding and interval between receipt of the primary award and receipt of the first follow-on award) associated with OppNet K18 awards to findings from evaluations of other NIH career development (K) awards, which usually target early-career investigators. We hypothesized that K18 award recipients might be (1) more successful than are other K award recipients in obtaining follow-on NIH research funding due to their career experience or (2) less successful due to the competing demands of other projects. By analyzing follow-on NIH research awards and interview data, we found that OppNet K18 award recipients were at least as successful as were other K award recipients in obtaining follow-on funding and may have been more successful by certain measures. K18 awards produce their outcomes with a lower investment per investigator than do other K awards, suggesting continued or enhanced use of the mechanism.