An Initial Evaluation of the NAG f90 Compiler

Directory of Open Access Journals (Sweden)

Michael Metcalf

1992-01-01

Full Text Available A few weeks before the formal publication of the ISO Fortran 90 Standard, NAG announced the world's first f90 compiler. We have evaluated the compiler by using it to assess the impact of Fortran 90 on the CERN Program Library.

Prospective communications research to support fly by light/power by wire

Science.gov (United States)

Game, David

1994-01-01

A NASA Research Grant NAG-1-1309, Distributed Fiber Optic Systems for Commercial Aircraft, was awarded during July 1991. This report primarily constitutes a summary of findings of the original background research done at that time. NASA is embarking on a research project to design the next generation of commercial aircraft, fly by light/power by wire. The objectives of this effort are to improve commercial aircraft design by (1) reducing the weight of the aircraft to improve efficiency and (2) improving the fault tolerance and safety of the aircraft by enhancing current systems with new technologies or introducing new systems into the aircraft.

Abundance of dioxygenase genes similar to Ralstonia sp strain U2 nagAc is correlated with naphthalene concentrations in coal tar-contaminated freshwater sediments

Energy Technology Data Exchange (ETDEWEB)

Dionisi, H.M.; Chewning, C.S.; Morgan, K.H.; Menn, F.M.; Easter, J.P; Sayler, G.S. [University of Tennessee, Knoxville, TN (United States). Center for Environmental Biotechnology

2004-07-01

We designed a real-time PCR assay able to recognize dioxygenase large-subunit gene sequences with more than 90% similarity to the Ralstonia sp. strain U2 nagAc gene (nagAc-like gene sequences) in order to study the importance of organisms carrying these genes in the biodegradation of naphthalene. Sequencing of PCR products indicated that this real-time PCR assay was specific and able to detect a variety of nagAc-like gene sequences. One to 100 ng of contaminated-sediment total DNA in 25-{mu}l reaction mixtures produced an amplification efficiency of 0.97 without evident PCR inhibition. The assay was applied to surficial freshwater sediment samples obtained in or in close proximity to a coal tar-contaminated Superfund site. Naphthalene concentrations in the analyzed samples varied between 0.18 and 106 mg/kg of dry weight sediment. The assay for nagAc-like sequences indicated the presence of (4.1 {+-} 0.7) X 10{sup 3} to (2.9 {+-} 0.3) X 10{sup 5} copies of nagAc-like dioxygenase genes per mug of DNA extracted from sediment samples. These values corresponded to (1.2 {+-} 0.6) X 10{sup 5} to (5.4 {+-} 0.4) X 10{sup 7} copies of this target per g of dry weight sediment when losses of DNA during extraction were taken into account. There was a positive correlation between naphthalene concentrations and nagAc-like gene copies per microgram of DNA = 0.89) and per gram of dry weight sediment = 0.77). These results provide evidence of the ecological significance of organisms carrying nagAc-like genes in the biodegradation of naphthalene.

Electrostatic electron cyclotron waves generated by low-energy electron beams

Czech Academy of Sciences Publication Activity Database

Menietti, J. D.; Santolík, Ondřej; Scudder, J. D.; Pickett, J. S.; Gurnett, D. A.

2002-01-01

Roč. 107, A10, 1285 (2002), s. SMP 8-1-8-11, doi: 10.1029/2001JA009223 ISSN 0148-0227 R&D Projects: GA ČR GA205/01/1064 Grant - others:NASA(US) NAG5-7943; NASA(US) NAG5-9561; NASA(US) NAG5-8119 Institutional research plan: CEZ:AV0Z3042911; CEZ:MSM 113200004 Keywords : low-energy electron beams * cyclotron frequency Subject RIV: DG - Athmosphere Sciences, Meteorology Impact factor: 2.245, year: 2002

Association of urinary KIM-1, L-FABP, NAG and NGAL with incident end-stage renal disease and mortality in American Indians with type 2 diabetes mellitus.

Science.gov (United States)

Fufaa, Gudeta D; Weil, E Jennifer; Nelson, Robert G; Hanson, Robert L; Bonventre, Joseph V; Sabbisetti, Venkata; Waikar, Sushrut S; Mifflin, Theodore E; Zhang, Xiaoming; Xie, Dawei; Hsu, Chi-Yuan; Feldman, Harold I; Coresh, Josef; Vasan, Ramachandran S; Kimmel, Paul L; Liu, Kathleen D

2015-01-01

Kidney injury molecule 1 (KIM-1), liver fatty acid-binding protein (L-FABP), N-acetyl-β-D-glucosaminidase (NAG) and neutrophil gelatinase-associated lipocalin (NGAL) are urinary biomarkers of renal tubular injury. We examined their association with incident end-stage renal disease (ESRD) and all-cause mortality in American Indians with type 2 diabetes. Biomarker concentrations were measured in baseline urine samples in 260 Pima Indians who were followed for a median of 14 years. HRs were reported per SD of creatinine (Cr)-normalised log-transformed KIM-1, NAG and NGAL, and for three categories of L-FABP. During follow-up, 74 participants developed ESRD and 101 died. Median concentrations of KIM-1/Cr, NAG/Cr and NGAL/Cr and the proportion of detectable L-FABP were highest in those with macroalbuminuria (p associated with ESRD (HR 1.59, 95% CI 1.20, 2.11) and mortality (HR 1.39, 95% CI 1.06, 1.82); L-FABP/Cr was inversely associated with ESRD (HR [for highest vs lowest tertile] 0.40, 95% CI 0.19, 0.83). Addition of NGAL/Cr to models that included albuminuria and glomerular filtration rate increased the c-statistic for predicting ESRD from 0.828 to 0.833 (p = 0.001) and for death from 0.710 to 0.722 (p = 0.018). Addition of L-FABP/Cr increased the c-statistic for ESRD from 0.828 to 0.832 (p = 0.042). In Pima Indians with type 2 diabetes, urinary concentrations of NGAL and L-FABP are associated with important health outcomes, but they are unlikely to add to risk prediction with standard markers in a clinically meaningful way given the small increase in the c-statistic.

40 CFR 86.1327-96 - Engine dynamometer test procedures; overview.

Science.gov (United States)

2010-07-01

... device, the exhaust pipe must be the same diameter as found in-use for at least 4 pipe diameters upstream... Exhaust Test Procedures § 86.1327-96 Engine dynamometer test procedures; overview. (a) The engine.... The exhaust emissions are diluted with ambient air and a continuous proportional sample is collected...

An upper limit on the sulphur abundance in HE 1327-2326

Science.gov (United States)

Bonifacio, P.; Caffau, E.; Venn, K. A.; Lambert, D. L.

2012-08-01

Context. Star HE 1327-2326 is a unique object, with the lowest measured iron abundance ([Fe/H] ~ -6) and a peculiar chemical composition that includes large overabundances of C, N, and O with respect to iron. One important question is whether the chemical abundances in this star reflect the chemical composition of the gas cloud from which it was formed or if they have been severely affected by other processes, such as dust-gas winnowing. Aims: We measure or provide an upper limit to the abundance of the volatile element sulphur, which can help to discriminate between the two scenarios. Methods: We observed HE 1327-2326 with the high resolution infra-red spectrograph CRIRES at the VLT to observe the S i lines of Multiplet 3 at 1045 nm. Results: We do not detect the S i line. A 3σ upper limit on the equivalent width (EW) of any line in our spectrum is EW winnowing, and the evidence coming from other elements (e.g., Na and Ti) is also inconclusive or contradictory. The formation of dust in the atmosphere versus an origin of the metals in a metal-poor supernova with extensive "fall-back" are not mutually exclusive. It is possible that dust formation distorts the peculiar abundance pattern created by a supernova with fall-back, thus the abundance ratios in HE 1327-2326 may be used to constrain the properties of the supernova(e) that produced its metals, but with some caution. Based on spectra obtained with CRIRES at the 8.2 m Antu ESO telescope, programme 386.D-0095.

Extramural Research Grants and Scientists’ Funding Strategies

DEFF Research Database (Denmark)

Grimpe, Christoph

2012-01-01

Although competitive funding of public research has been characterised as providing output incentives that raise efficiency and productivity, we know very little about whether the quality of a scientist’s research is in fact the primary award criterion on which funding bodies base their grant...... decision. This paper provides insights into scientists’ strategies for obtaining project-based research funding in the presence of multiple funding opportunities. It draws a distinction between four types of grants, including the Sixth Framework Programme for Research and Technological Development (FP6......), government, foundation, and industry grants. Based on a sample of more than 800 scientists at universities and public research institutes in Germany, the results indicate that scientist productivity measured in terms of publication and patent stock is a statistically significant determinant only...

European Association of Echocardiography: Research Grant Programme.

Science.gov (United States)

Gargani, Luna; Muraru, Denisa; Badano, Luigi P; Lancellotti, Patrizio; Sicari, Rosa

2012-01-01

The European Society of Cardiology (ESC) offers a variety of grants/fellowships to help young professionals in the field of cardiological training or research activities throughout Europe. The number of grants has significantly increased in recent years with contributions from the Associations, Working Groups and Councils of the ESC. The European Association of Echocardiography (EAE) is a registered branch of the ESC and actively takes part in this initiative. One of the aims of EAE is to promote excellence in research in cardiovascular ultrasound and other imaging modalities in Europe. Therefore, since 2008, the EAE offers a Research Grant Programme to help young doctors to obtain research experience in a high standard academic centre (or similar institution oriented to clinical or pre-clinical research) in an ESC member country other than their own. This programme can be considered as a valorization of the geographical mobility as well as cultural exchanges and professional practice in the field of cardiovascular imaging. The programme has been very successful so far, therefore in 2012 the EAE has increased its offer to two grants of 25,000 euros per annum each.

Src inhibitor herbimycin A prevents 132.7 kDa tyrosine phosphatase activity in Ramos Burkitt's lymphoma B cell line

International Nuclear Information System (INIS)

Hristov, K.; Mitev, V.; Knox, K.

2006-01-01

Reversible tyrosine phosphorylation, regulation of expression and proteolytic cleavage control tyrosine phosphatase contribution for the signalling pathways of B-cell antigen receptor (BCR), and CD40 during B cell selection. We used Ramos-BL B cell line to determine whether BCR and CD40 stimulation, or inhibition of the Src - tyrosine kinase, tyrosine phosphatase and caspase activity have an effect on the tyrosine phosphatase activities determined on in-gel phosphatase assay. The tyrosine phosphatase activities present in whole cell lysates of Ramos-BL B cells following treatment with 20 μg/ml anti-IgM, 1 μg/ml anti-CD40, 10 μM herbimycin A, 178 μM vanadate,100 μM phenylarsine oxide and 10 μM zVAD-fmk were detected with an in-gel phosphatase assay. Seven major tyrosine phosphatase activities with approximate molecular weight of 132.7, 63.9, 60.3, 54.2, 49.7, 44.6, and 39 kDa are present in whole cell lysates of Ramos-BL B cells. Treatment with Src-PTK inhibitor herbimycin A prevents 132.7 kDa tyrosine phosphatase activity. We conclude that the catalytic activity of Src-PTK in Ramos-BL B cells is critical for the presence of this 132.7 kDa tyrosine phosphatase activity. (authors)

Water Resources Research Grant Program project descriptions, fiscal year 1987

Science.gov (United States)

,

1987-01-01

This report contains information on the 34 new projects funded by the United States Geological Survey 's Water Resources Research Grant Program in fiscal year 1987 and on 3 projects completed during the year. For the new projects, the report gives the grant number, project title, performing organization, principal investigator(s), and a project description that includes: (1) identification of water related problems and problem-solution approach (2) contribution to problem solution, (3) objectives, and (4) approach. The 34 projects include 12 in the area of groundwater quality problems, 12 in the science and technology of water quality management, 1 in climate variability and the hydrologic cycle, 4 in institutional change in water resources management, and 5 in surface water management. For the three completed projects, the report furnishes the grant number; project title; performing organization; principal investor(s); starting data; data of receipt of final report; and an abstract of the final report. Each project description provides the information needed to obtain a copy of the final report. The report contains tables showing: (1) proposals received according to area of research interest, (2) grant awards and funding according to area of research interest, (3) proposals received according to type of submitting organization, and (4) awards and funding according to type of organization. (Author 's abstract)

Integrated Knowledge Translation and Grant Development: Addressing the Research Practice Gap through Stakeholder-informed Research.

Science.gov (United States)

Henderson, Joanna; Brownlie, Elizabeth; Rosenkranz, Susan; Chaim, Gloria; Beitchman, Joseph

2013-11-01

We describe our stakeholder engagement process for grant application development that occurred as part of our integrated knowledge translation plan and make recommendations for researchers. In phase 1, a stakeholder consultation group was developed. In phase 2, surveys regarding knowledge gathering, research agenda, and research collaboration preferences were sent to 333 cross-sectoral youth-serving organizations in Ontario, including family and consumer organizations. In phase 1, 28 stakeholders from six sectors participated in the consultation group and provided input on multiple aspects of the proposal. Through this process, 19 stakeholders adopted formal roles within the project. In phase 2, 206 surveys were received (response rate = 62%). Survey responses supported the grant focus (concurrent youth mental health and substance use problems). Respondents also prioritized project goals and provided specific feedback on research and knowledge translation. Finally, although some stakeholders chose greater involvement, most survey respondents indicated a preference for a moderate level of participation in research rather than full team membership. Despite short timelines and feasibility challenges, stakeholders can be meaningfully engaged in and contribute to the grant proposal development process. Consideration is needed for the practical challenges that stakeholder organizations face in supporting and participating in research.

Operations and support cost modeling of conceptual space vehicles

Science.gov (United States)

Ebeling, Charles

1994-01-01

The University of Dayton is pleased to submit this annual report to the National Aeronautics and Space Administration (NASA) Langley Research Center which documents the development of an operations and support (O&S) cost model as part of a larger life cycle cost (LCC) structure. It is intended for use during the conceptual design of new launch vehicles and spacecraft. This research is being conducted under NASA Research Grant NAG-1-1327. This research effort changes the focus from that of the first two years in which a reliability and maintainability model was developed to the initial development of an operations and support life cycle cost model. Cost categories were initially patterned after NASA's three axis work breakdown structure consisting of a configuration axis (vehicle), a function axis, and a cost axis. A revised cost element structure (CES), which is currently under study by NASA, was used to established the basic cost elements used in the model. While the focus of the effort was on operations and maintenance costs and other recurring costs, the computerized model allowed for other cost categories such as RDT&E and production costs to be addressed. Secondary tasks performed concurrent with the development of the costing model included support and upgrades to the reliability and maintainability (R&M) model. The primary result of the current research has been a methodology and a computer implementation of the methodology to provide for timely operations and support cost analysis during the conceptual design activities.

1999 Horton Research Grants awarded

Science.gov (United States)

The Horton (Hydrology) Research Grant Committee presented three grants at the 1999 AGU Spring Meeting in Boston, Massachusetts, last June. S. Jean Birks is currently a Ph.D. candidate in the Earth Sciences Department at the University of Waterloo under the supervision of Tom Edwards and Victoria Remenda (Queen's University). The title of her Ph.D. dissertation is “Long-term Natural Tracer Migration in Thick Unfractured Clay: Implications for Reconstructing the Post-glacial Isotopic History of Precipitation from Aquitards in the Northern Great Plains.” Jean received her B.Sc. in geography and environmental science from McMaster University and her M.Sc. in hydrogeology from Queen's University.

An output evaluation of a health research foundation's enhanced grant review process for new investigators.

Science.gov (United States)

Hammond, Gregory W; Lê, Mê-Linh; Novotny, Tannis; Caligiuri, Stephanie P B; Pierce, Grant N; Wade, John

2017-06-19

We assessed the ability of the Manitoba Medical Service Foundation (MMSF, a small not-for-profit foundation affiliated with Manitoba Blue Cross) to determine the best candidates for selection to receive research funding support among new researchers applying to the Research Operating Grants Programme (ROGP). Using bibliometric and grants funding analyses, we retrospectively compared indices of academic outputs from five cohorts of MMSF-funded and not MMSF-funded applicants to the annual MMSF ROGP over 2008 to 2012, from 1 to 5 years after having received evaluation decisions from the MMSF enhanced grant review process. Those researchers funded by the MMSF competition (MMSF-funded) had a statistically significant greater number of publications, a higher h-index and greater national Tri-Council (TC) funding, versus those not selected for funding (not MMSF-funded). MMSF-funded applicants and the Manitoba research community have created a strong and rapid (within 1 to 5 years of receiving the MMSF grant) local economic return on investment associated with the MMSF ROGP that supports new investigators, of approximately nine-fold for TC grants by the principal investigator, and of 34-fold for the principal investigator on collaborative (total) TC grants. The use of small amounts of seed money for competitive research grants at early stages of an MMSF-funded applicant's career correlates with future short-term success of that applicant. The ability to correctly select promising candidates who subsequently demonstrate greater academic performance after the MMSF funding shows the selection process and the ROGP to be of merit. Multiple components may have contributed to this outcome, including a direct presentation and interview process of the candidate with five-person selection subcommittees, plus an assessment by an external reviewer (the enhanced grant review process). The selection methods used here may add value to the research grant selection processes of new

On the Possibility of Linear Modelling the Human Arm Neuromuscul Apparatus

Czech Academy of Sciences Publication Activity Database

Frolov, A. A.; Dufossé, M.; Řízek, Stanislav; Kaladjian, A.

2000-01-01

Roč. 82, č. 6 (2000), s. 499-515 ISSN 0340-1200 Grant - others:INTAS-RFBR(RU) 95-1327; BARRANDE(XE) 97-0109/FR-97-062; RFBR(RU) 98-04-48277 Institutional research plan: AV0Z1030915 Subject RIV: BA - General Mathematics Impact factor: 1.185, year: 2000

Internships, employment opportunities, and research grants

Science.gov (United States)

,

2015-01-01

As an unbiased, multidisciplinary science organization, the U.S. Geological Survey (USGS) is dedicated to the timely, relevant, and impartial study of the health of our ecosystems and environment, our natural resources, the impacts of climate and land-use change, and the natural hazards that threaten us. Opportunities for undergraduate and graduate students and faculty to participate in USGS science are available in the selected programs described below. Please note: U.S. citizenship is required for all government positions.This publication has been superseded by USGS General Information Product 165 Grant Opportunities for Academic Research and Training and USGS General Information Product 166 Student and Recent Graduate Employment Opportunities.This publication is proceeded by USGS General Information Product 80 Internships, Employment Opportunities, and Research Grants published in 2008.

How to write an educational research grant: AMEE Guide No. 101.

Science.gov (United States)

Blanco, Maria A; Gruppen, Larry D; Artino, Anthony R; Uijtdehaage, Sebastian; Szauter, Karen; Durning, Steven J

2016-01-01

Writing an educational research grant in health profession education is challenging, not only for those doing it for the first time but also for more experienced scholars. The intensity of the competition, the peculiarities of the grant format, the risk of rejection, and the time required are among the many obstacles that can prevent educational researchers with interesting and important ideas from writing a grant, that could provide the funding needed to turn their scholarly ideas into reality. The aim of this AMEE Guide is to clarify the grant-writing process by (a) explaining the mechanics and structure of a typical educational research grant proposal, and (b) sharing tips and strategies for making the process more manageable.

Inhibition of GlcNAc-Processing Glycosidases by C-6-Azido-NAG-Thiazoline and Its Derivatives

Czech Academy of Sciences Publication Activity Database

Krejzová, Jana; Šimon, Petr; Ježová-Kalachová, Lubica; Kulik, Natallia; Bojarová, Pavla; Marhol, Petr; Pelantová, Helena; Cvačka, Josef; Ettrich, Rüdiger; Slámová, Kristýna; Křen, Vladimír

2014-01-01

Roč. 19, č. 3 (2014), s. 3471-3488 ISSN 1420-3049 Institutional support: RVO:61388971 ; RVO:67179843 ; RVO:61388963 Keywords : NAG-thiazoline * enzyme inhibition * O-GlcNAcase Subject RIV: CE - Biochemistry Impact factor: 2.416, year: 2014

Grant-Writing Bootcamp: An Intervention to Enhance the Research Capacity of Academic Women in STEM.

Science.gov (United States)

Smith, Jessi L; Stoop, Chatanika; Young, Micaela; Belou, Rebecca; Held, Suzanne

2017-07-01

Broadening the participation of women in science, technology, engineering, and mathematical (STEM) fields is more than a social-justice issue; diversity is paramount to a thriving national research agenda. However, women face several obstacles to fully actualizing their research potential. Enhancing the research capacity and opportunity of women faculty requires purposeful changes in university practice. Therefore, we designed an intervention, a grant-writing bootcamp informed by self-determination theory (Deci and Ryan 2012), to support the participants' feelings of relatedness, autonomy, and competence. Three grant-writing bootcamps were run over an 18-month period. Using a pre- and post-test design over the span of 1 year (and contrasting results with a comparison sample who were not part of the intervention) showed that the women participating in the grant-writing bootcamp significantly increased the number of external grants submitted, the number of proposals led as principal investigator, the number of external grants awarded, and the amount of external funding dollars awarded.

Orbital Parameters and Chemical Composition of Four White Dwarfs in Post-Common-Envelope Binaries

Czech Academy of Sciences Publication Activity Database

Kawka, Adela; Vennes, S.; Dupuis, J.; Chayer, P.; Lanz, T.

2008-01-01

Roč. 675, č. 2 (2008), s. 1518-1530 ISSN 0004-637X R&D Projects: GA ČR(CZ) GP205/05/P186; GA MŠk(CZ) LC06014 Grant - others: NASA (US) NAG5-6551; NASA (US) NAG-11717 Institutional research plan: CEZ:AV0Z10030501 Keywords : stars * spectroscopic * abundances Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 6.331, year: 2008

The grant writer's handbook how to write a research proposal and succeed

CERN Document Server

Crawley, Gerard M

2016-01-01

The Grant Writer's Handbook: How to Write a Research Proposal and Succeed provides useful and practical advice on all aspects of proposal writing, including developing proposal ideas, drafting the proposal, dealing with referees, and budgeting. The authors base their advice on many years of experience writing and reviewing proposals in many different countries at various levels of scientific maturity. The book describes the numerous kinds of awards available from funding agencies, in particular large collaborative grants involving a number of investigators, and addresses the practical impact of a grant, which is often required of proposals. In addition, information is provided about selection of reviewers and the mechanics of organizing a research grant competition to give the proposal writer the necessary background information. The book includes key comments from a number of experts and is essential reading for anyone writing a research grant proposal.The Grant Writer's Handbook's companion website, featuri...

How to Get Your First Research Grant

OpenAIRE

Trumbo, B. E.

1989-01-01

In applying for a research grant, a young statistician or probabilist faces keen competition for limited funds. The quality of the research proposed and the qualifications of the researcher are major criteria in evaluating a project for funding. However, chances for funding can be improved if the application is carefully written, based upon an understanding of how it will be evaluated. In applying for support, the young researcher should consider the advantages and disadvantages of the variou...

Inhibition of microbial β-N-acetylhexosaminidases by 4-deoxy- and galacto-analogues of NAG-thiazoline

Czech Academy of Sciences Publication Activity Database

Krejzová, Jana; Ježová-Kalachová, Lubica; Šimon, Petr; Pelantová, Helena; Slámová, Kristýna; Křen, Vladimír

2014-01-01

Roč. 24, č. 22 (2014), s. 5321-5323 ISSN 0960-894X R&D Projects: GA ČR(CZ) GAP207/11/0629; GA MŠk(CZ) 7E11011 Institutional support: RVO:61388971 Keywords : NAG-thiazoline * enzyme inhibition Subject RIV: CE - Biochemistry Impact factor: 2.420, year: 2014

Child Support Grant access and receipt among 12-week-old infants in an urban township setting in South Africa.

Science.gov (United States)

Zembe-Mkabile, Wanga; Doherty, Tanya; Sanders, David; Jackson, Debra

2014-01-01

Cash transfers (CTs) are increasingly used as a strategy to alleviate poverty and improve child health outcomes in low- and middle-income countries. The Child Support Grant (CSG) is the largest CT programme in South Africa, and on the continent, targeting poor children from birth until the age of 18 with a monthly sum of R300 (USD30). Evidence on the CSG shows that early receipt of the grant is associated with improved child health outcomes. Since its implementation, one of the major concerns about the grant has been take-up rates, particularly for younger children. This paper reports results on take-up rates for 12-week-old infants residing in an urban township in South Africa. This is a descriptive study utilising data from a community-based, cluster-randomised trial which evaluated a programme providing pregnancy and post-natal home visits by community health workers to 3,494 mothers in Umlazi township, South Africa. At the 12-week visit, half (52%) of the mothers who had enrolled in the study had applied for the CSG on behalf of their children, while 85% of the mothers who had not applied were still planning to apply. Only 38% (1,327) of all children had received the CSG. In this study, many mothers had not applied for the CSG in the first few months after delivery, and only a third of children had accessed the grant. Further research is needed to understand what the current barriers are that prevent mothers from applying for this important form of social protection in the early months after delivery.

Child Support Grant access and receipt among 12-week-old infants in an urban township setting in South Africa

Directory of Open Access Journals (Sweden)

Wanga Zembe-Mkabile

2014-08-01

Full Text Available Background: Cash transfers (CTs are increasingly used as a strategy to alleviate poverty and improve child health outcomes in low- and middle-income countries. The Child Support Grant (CSG is the largest CT programme in South Africa, and on the continent, targeting poor children from birth until the age of 18 with a monthly sum of R300 (USD30. Evidence on the CSG shows that early receipt of the grant is associated with improved child health outcomes. Since its implementation, one of the major concerns about the grant has been take-up rates, particularly for younger children. This paper reports results on take-up rates for 12-week-old infants residing in an urban township in South Africa. Methods: This is a descriptive study utilising data from a community-based, cluster-randomised trial which evaluated a programme providing pregnancy and post-natal home visits by community health workers to 3,494 mothers in Umlazi township, South Africa. Results: At the 12-week visit, half (52% of the mothers who had enrolled in the study had applied for the CSG on behalf of their children, while 85% of the mothers who had not applied were still planning to apply. Only 38% (1,327 of all children had received the CSG. Conclusions: In this study, many mothers had not applied for the CSG in the first few months after delivery, and only a third of children had accessed the grant. Further research is needed to understand what the current barriers are that prevent mothers from applying for this important form of social protection in the early months after delivery.

A 25-year analysis of the American College of Gastroenterology Research Grant Program:

Science.gov (United States)

Crockett, Seth D.; Dellon, Evan S.; Bright, Stephanie D.; Shaheen, Nicholas J.

2011-01-01

Introduction The American College of Gastroenterology (ACG) has awarded research grants for 25 years. We assessed the characteristics of grant recipients, their current academic status, and the likelihood of publication resulting from the grant. Methods Demographic data, year and amount of award, title of project, and recipient’s institution were extracted from ACG databases. Using ACG reports and medical literature search engines, we assessed publication based on grant-funded research, as well as career publication record. We also determined the current position of awardees. Similar analysis was performed for recipients of junior investigator awards. Results A total of 396 clinical research awards totaling $5,374,497 ($6,867,937 in 2008 dollars) were awarded to 341 recipients in the 25 years between 1983 and 2008. The most commonly funded areas of research were endoscopy (22% of awards) and motility/functional disorders (21%). At least one peer-reviewed publication based on grant-funded research occurred in 255 of the awards (69%). Higher award value was associated with subsequent publication. Of 341 past awardees, 195 (62%) are currently in academic positions. Factors associated with staying in academics included higher award value (pacademics. Overall, the mean cost in grant dollars per published paper based on the research was $14,875. Conclusion The majority of ACG grant recipients published the results of their research and remained in academics. Higher amount of award, holding an advanced degree, and publication were associated with careers in academics. The ACG research grant award program is an important engine of investigation, publications, and academic career development in the field of gastroenterology. PMID:19319125

1H, 15N and 13C backbone and side-chain resonance assignments of a family 32 carbohydrate-binding module from the Clostridium perfringens NagH.

Science.gov (United States)

Grondin, Julie M; Chitayat, Seth; Ficko-Blean, Elizabeth; Boraston, Alisdair B; Smith, Steven P

2012-10-01

The Gram-positive anaerobe Clostridium perfringens is an opportunistic bacterial pathogen that secretes a battery of enzymes involved in glycan degradation. These glycoside hydrolases are thought to be involved in turnover of mucosal layer glycans, and in the spread of major toxins commonly associated with the development of gastrointestinal diseases and gas gangrene in humans. These enzymes employ multi-modularity and carbohydrate-binding function to degrade extracellular eukaryotic host sugars. Here, we report the full (1)H, (15)N and (13)C chemical shift resonance assignments of the first family 32 carbohydrate-binding module from NagH, a secreted family 84 glycoside hydrolase.

The use of recombinant nAG protein In spinal cord crush injury in a rat model

International Nuclear Information System (INIS)

Al-Qattan, M.M.; Al-Motairi, M.; Ah-Habib, A.

2017-01-01

Objective: To evaluate the therapeutic properties of nAG protein during the recovery following acute spinal cord injuries in the rat. Study Design: An experimental study. Place and Duration of Study: King Saud University, Riyadh, Saudi Arabia, from September 2014 to September 2015. Methodology: Eight rats were studied (4 control rats and 4 experimental rats; and hence 50% were controls and 50% were experimental). All rats were subjected to an acute spinal cord injury using the aneurysmal clip injury model. Immediately after the injury, a single intra-dural injection of either normal saline (in the control group) or the nAG protein (in the experimental group) was done. Assessment of both groups was done over a 6-week period with regard to weight maintenance, motor recovery scores, MRI and histopathology of the injury site. Results: Weight maintenance was seen in the experimental and not in the control rats. Starting at 3 weeks after injury, the motor recovery was significantly (p<0.05) better in the experimental group. MRI assessment at 6 weeks showed better maintenance of cord continuity and less fluid accumulation at the injury site in the nAG-treated group. Just proximal to the injury site, there was less gliosis in the experimental group compared to the control group. At the crush injury site, there was less tissue architecture distortion, less vacuole formation, and less granulation tissue formation in the experimental group. Conclusion: The local injection nAG protein enhances neuro-restoration, reduces gliosis, and reduces vacuole/ granulation tissue formation following acute spinal cord crush injury in the rat aneurysmal clip animal model. (author)

A phospho-sugar binding domain homologous to NagB enzymes regulates the activity of the central glycolytic genes repressor.

Science.gov (United States)

Doan, Thierry; Martin, Laetitia; Zorrilla, Silvia; Chaix, Denis; Aymerich, Stéphane; Labesse, Gilles; Declerck, Nathalie

2008-06-01

CggR belongs to the SorC family of bacterial transcriptional regulators which control the expression of genes and operons involved in carbohydrate catabolism. CggR was first identified in Bacillus subtilis where it represses the gapA operon encoding the five enzymes that catalyze the central part of glycolysis. Here we present a structure/function study demonstrating that the C-terminal region of CggR regulates the DNA binding activity of this repressor in response to binding of a phosphorylated sugar. Molecular modeling of CggR revealed a winged-helix DNA-binding motif followed by a C-terminal domain presenting weak but significant homology with glucosamine-6-phosphate deaminases from the NagB family. In silico ligand screening suggested that the CggR C-terminal domain would bind preferentially bi-phosphorylated compounds, in agreement with previous studies that proposed fructuose-1,6-biphosphate (FBP) as the inducer metabolite. In vitro, FBP was the only sugar compound capable of interfering with CggR cooperative binding to DNA. FBP was also found to protect CggR against trypsin degradation at two arginine residues predicted to reside in a mobile loop forming the active site lid of the NagB enzymes. Replacement of residues predicted to interact with FBP led to mutant CggR with altered repressor activity in vivo but retaining their structural integrity and DNA binding activity in vitro. Interestingly, some of the mutant repressors responded with different specificity towards mono- and di-phospho-fructosides. Based on these results, we propose that the activity of the CggR-like repressors is controlled by a phospho-sugar binding (PSB) domain presenting structural and functional homology with NagB enzymes. (c) 2008 Wiley-Liss, Inc.

Canada-Africa Research Exchange Grants (CAREG) : Pilot Phase ...

International Development Research Centre (IDRC) Digital Library (Canada)

The Canada-Africa Research Exchange Grants (CAREG) were designed to rectify this situation by supporting a series of short-term research or training exchanges between Canadian and African ... IDRC is pleased to announce the results of its 2017 call for proposals to establish Cyber Policy Centres in the Global South.

New Results from the Flare Genesis Experiment

Science.gov (United States)

Rust, D. M.; Bernasconi, P. N.; Eaton, H. A.; Keller, C.; Murphy, G. A.; Schmieder, B.

2000-05-01

From January 10 to 27, 2000, the Flare Genesis solar telescope observed the Sun while suspended from a balloon in the stratosphere above Antarctica. The goal of the mission was to acquire long time series of high-resolution images and vector magnetograms of the solar photosphere and chromosphere. Images were obtained in the magnetically sensitive Ca I line at 6122 Angstroms and at H-alpha (6563 Angstroms). The FGE data were obtained in the context of Max Millennium Observing Campaign #004, the objective of which was to study the ``Genesis of Solar Flares and Active Filaments/Sigmoids." Flare Genesis obtained about 26,000 usable images on the 8 targeted active regions. A preliminary examination reveals a good sequence on an emerging flux region and data on the M1 flare on January 22, as well as a number of sequences on active filaments. We will present the results of our first analysis efforts. Flare Genesis was supported by NASA grants NAG5-4955, NAG5-5139, and NAG5-8331 and by NSF grant OPP-9615073. The Air Force Office of Scientific Research and the Ballistic Missile Defense Organization supported early development of the Flare Genesis Experiment.

Interdisciplinary Research to Elucidate Mechanisms Governing Silver Nanoparticle Fate and Transport in Porous Media

Science.gov (United States)

Pennell, K. D.; Mittleman, A.; Taghavy, A.; Fortner, J.; Lantagne, D.; Abriola, L. M.

2015-12-01

Interdisciplinary Research to Elucidate Mechanisms Governing Silver Nanoparticle Fate and Transport in Porous Media Anjuliee M. Mittelman, Amir Taghavy, Yonggang Wang, John D. Fortner, Daniele S. Lantagne, Linda M. Abriola and Kurt D. Pennell* Detailed knowledge of the processes governing nanoparticle transport and reactivity in porous media is essential for accurate predictions of environmental fate, water and wastewater treatment system performance, and assessment of potential risks to ecosystems and water supplies. To address these issues, an interdisciplinary research team combined experimental and mathematical modeling studies to investigate the mobility, dissolution, and aging of silver nanoparticles (nAg) in representative aquifer materials and ceramic filters. Results of one-dimensional column studies, conducted with water-saturated sands maintained at pH 4 or 7 and three levels of dissolved oxygen (DO), revealed that fraction of silver mass eluted as Ag+ increased with increasing DO level, and that the dissolution of attached nAg decreased over time as a result of surface oxidation. A hybrid Eulerain-Lagragian nanoparticle transport model, which incorporates DO-dependent dissolution kinetics and particle aging, was able to accurately simulate nAg mobility and Ag+ release measured in the column experiments. Model sensitivity analysis indicated that as the flow velocity and particle size decrease, nAg dissolution and Ag+ transport processes increasingly govern silver mobility. Consistent results were obtained in studies of ceramic water filters treated with nAg, where silver elution was shown to be governed by nAg dissolution to form Ag+ and subsequent cation exchange reactions. Recent studies explored the effects of surface coating aging on nAg aggregation, mobility and dissolution. Following ultraviolet light, nAg retention in water saturated sand increased by 25-50%, while up to 50% of the applied mass eluted as Ag+ compared to less than 1% for un-aged nAg

76 FR 11765 - Education Research and Special Education Research Grant Programs; Institute of Education Sciences...

Science.gov (United States)

2011-03-03

... DEPARTMENT OF EDUCATION Education Research and Special Education Research Grant Programs; Institute of Education Sciences; Overview Information; Education Research and Special Education Research.... SUMMARY: The Director of the Institute of Education Sciences (Institute) announces the Institute's FY 2012...

Research and Grant Management: The Role of the Project Management Office (PMO) in a European Research Consortium Context

Science.gov (United States)

Wedekind, Gerben Kristian; Philbin, Simon Patrick

2018-01-01

This paper illustrates how a university-based project management office (PMO) can provide focused support across the entire grant project lifecycle within a European research context. In recent years, EU (European Union) research and innovation grant programs have increasingly shifted to support multidisciplinary consortia composed of industry,…

Initiation of new category of grant-in-aid for energy research by the Ministry of Education, science and culture

International Nuclear Information System (INIS)

Ohkado, Takashi

1980-01-01

Starting from fiscal 1980, among the grants-in-aid from the Ministry of Education, the one for energy researches was instituted with yearly budget of yen 1,400 million, intended for nuclear fusion research and other energy researches. In the guidance for the grants-in-aid in fiscal 1980, the formula of application was stated. The number of applicants was unexpectedly small, however. For the purpose of information, the following matters are described: the background for the initiation, significance and purpose of the grant-in-aid, the screening examination and its results, etc. The gist of instituting the grant-in-aid for energy researches is as follows. First, as for nuclear fusion research, assuming the advances in the next ten years, efforts are to be made in such delayed studies as those on reactor material and tritium technology. As for other energy researches, other features than the research and development having been carried out so far are to be pursued. (J.P.N.)

SELECTIVE EVALUATION OF TWO URINARY ENZYMES (NAG AND AAP BEFORE AND AFTER UNILATERAL SHOCK WAVE LITHOTRIPSY

Directory of Open Access Journals (Sweden)

M. R. Nikoobakht

2006-09-01

Full Text Available Biological effects extracorporeal shock wave lithotripsy (ESWL is not precisely known. We have evaluated two urinary enzymes activity N-acetyl-B-D-glucosamine (NAG and alanine amino peptidase (AAP before and after unilateral ESWL as markers for renal parenchymal damage. Forty eight patients with kidney stones (mean age 39 who had presented for the first time or at least one year after their previous lithotripsy underwent ESWL. Urinary specimens were collected before and after first, third and seventh days of lithotripsy and NAG, AAP were evaluated. These enzymes displayed the greatest activity 24 hours after ESWL with significant difference compared to the control group, (P < 0.05 versus 0.02. Elevation of urinary enzymes activity correlated with stone size particularly stones larger than 2 cm. These data suggest that there is some tubular and parenchymal damage induced by ESWL that needs time to get improved. The higher urinary enzyme activity in patients with larger stones ( > 2 cm is probably related to injury resulting from passage of smaller stones, produced after lithotripsy of a large stone, and it is suggested that these patients are treated with a safer procedure.

Concocting that Magic Elixir: Successful Grant Application Writing in Dissemination and Implementation Research.

Science.gov (United States)

Brownson, Ross C; Colditz, Graham A; Dobbins, Maureen; Emmons, Karen M; Kerner, Jon F; Padek, Margaret; Proctor, Enola K; Stange, Kurt C

2015-12-01

This paper reports core competencies for dissemination and implementation (D&I) grant application writing and provides tips for writing a successful proposal. Two related phases were used to collect the data: a card sorting process among D&I researchers and an expert review among a smaller set of researchers. Card sorting was completed by 123 respondents. In the second phase, a series of grant application writing tips were developed based on the combined 170 years of grant review experience of the writing team. The card sorting resulted in 12 core competencies for D&I grant application writing that covered the main sections in a grant application to the US National Institutes of Health: (a) specific aims that provide clear rationale, objectives, and an overview of the research plan; (b) significance that frames and justifies the importance of a D&I question; (c) innovation that articulates novel products and new knowledge; and (d) approach that uses a relevant D&I model, addresses measurement and the D&I context, and includes an analysis plan well-tied to the aims and measures. Writing a successful D&I grant application is a skill that can be learned with experience and attention to the core competencies articulated in this paper. © 2015 Wiley Periodicals, Inc.

Analysis of the distribution and scholarly output from National Institute of Academic Anaesthesia (NIAA) research grants.

Science.gov (United States)

El-Boghdadly, K; Docherty, A B; Klein, A A

2018-06-01

The National Institute of Academic Anaesthesia (NIAA) was founded in 2008 to lead a UK strategy for developing academic anaesthesia. We aimed to assess the distribution of applications and quantify the academic returns of NIAA-supported research grants, as this has hitherto not been analysed. We sought data on the baseline characteristics of all grant applicants and recipients. Every grant recipient from 2008 to 2015 was contacted to ascertain the status of their supported research projects. We also examined Google Scholar, Scopus ® database and InCites Journal Citation Reports for citation, author and journal metrics, respectively. In total, 495 research project applications were made, with 150 grants being awarded. Data on 121 out of 150 (80.7%) grant awards, accounting for £3.5 million, were collected, of which 91 completed studies resulted in 140 publications and 2759 citations. The median (IQR [range]) time to first or only publication was 3 (2-4 [0-9]) years. The overall cost per publication was £14,970 (£7457-£24,998 [£2212-£73,755]) and the cost per citation was £1515 (£323-£3785 [£70-£36,182]), with 1 (0-2 [0-8]) publication and 4 (0-25 [0-265]) citations resulting per grant. The impact factor of journals in which publications arose was 4.7 (2.5-6.2 [0-47.8]), with the highest impact arising from clinical and basic science studies, particularly in the fields of pain and peri-operative medicine. Grants were most frequently awarded to clinical and basic science categories of study, but in terms of specialty, critical care medicine and peri-operative medicine received the greatest number of grants. Superficially, there seemed a geographical disparity, with 123 (82%) grants being awarded to researchers in England, London receiving 48 (32%) of these. However, this was in proportion to the number of grant applications received by country or city of application, such that there was no significant difference in overall success rates. There was no

Toward 10(exp 9) GPS geodesy: Vector baselines, Earth rotation and reference frames

Science.gov (United States)

Schutz, Bob E.

1993-01-01

The University of Texas Center for Space Research research efforts under NASA Grant No. NAG-1936 from 1 Jan. 1992 - 31 Dec. 1992 were in the following areas: GPS orbit accuracy assessments and efforts to improve the accuracy; analysis of global GPS data collected during the first three months of the IGS campaign, and analysis of regional data. A brief summary of each of the above activities is presented in the following.

Bling My Research! A Mock Grant Panel Activity Illustrating the Importance of Basic Research

Science.gov (United States)

Leander, Celeste A.; Whitton, Jeannette

2010-01-01

First-year university students have misconceptions about the source and dynamics of publicly funded research money. We designed an activity in which students take part in a mock grant panel. The results indicated a strong tendency toward student funding of applied medical research at the expense of basic research. Exposure to a few examples of…

Research support by doctoral-granting colleges/schools of nursing.

Science.gov (United States)

Yoon, Saun-Joo Lee; Wolfe, Sandra; Yucha, Carolyn B; Tsai, Peishan

2002-01-01

Colleges and schools of nursing with doctoral programs focus on developing quality research programs. One effective way of managing and nurturing a research program is through the implementation of a nursing research office or center. The purpose of this study is to describe the resources provided by the colleges/schools of nursing with doctoral programs for research development. A self-report questionnaire, developed by the research team, was mailed to all schools of nursing offering doctoral programs. The response rate was 79 per cent (65/82 schools). Results indicated that 56 schools (86.2 per cent) have designated research support offices. The main goals of nursing research offices are to increase the amount of extramural funding and to promote dissemination of scholarly work via publications and presentations. The majority of research offices provide assistance with grants and the research process and offer educational programs. Most doctoral-granting schools are providing some support for research activities. However, the degree of investment in research support varied widely among the responding schools. This study suggests that it takes both time and institutional commitment to build a successful research environment. Although necessary for research development, support services are not sufficient by themselves. Instead, they need to be considered in the light of individual (e.g., faculty interest and motivation) and group (e.g., culture of scholarship) factors within each school. Copyright 2002 by W.B. Saunders Company

Supporting Knowledge Mobilization and Research Impact Strategies in Grant Applications

Science.gov (United States)

Phipps, David; Jensen, Krista E.; Johnny, Michael; Poetz, Anneliese

2016-01-01

Each application to the National Science Foundation (NSF) must contain a Broader Impact (BI) strategy. Similarly, grant applications for most research funders in Canada and the UK require strategies to support the translation of research into impacts on society; however, the guidance provided to researchers is too general to inform the specific…

Using curriculum vitae to compare some impacts of NSF research grants with research center funding

OpenAIRE

Monica Gaughan; Barry Bozeman

2002-01-01

While traditional grants remain central in US federal support of academic scientists and engineers, the role of multidisciplinary NSF Centers is growing. Little is known about how funding through these Centers affects scientific output or (as is an NSF aim) increases academic collaboration with industry. This paper tests the use of CVs to examine how Center funding affects researchers' publication rates and their obtaining industry grants. Copyright , Beech Tree Publishing.

Structure of the lunar wake: Two-dimensional global hybrid simulations

Czech Academy of Sciences Publication Activity Database

Trávníček, Pavel; Hellinger, Petr; Schriver, D.; Bale, S. D.

2005-01-01

Roč. 32, - (2005), L06102/1-L06102/4 ISSN 0094-8276 R&D Projects: GA ČR(CZ) GA205/05/1011 Grant - others:ESA(XE) PRODEX 14529; NSF(US) INT- 0010111; NASA (US) NAG5-11804 Institutional research plan: CEZ:AV0Z30420517 Keywords : hybrid simulations * lunar wake Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 2.491, year: 2005

Solar wind proton temperature anisotropy: Linear theory and WIND/SWE observations

Czech Academy of Sciences Publication Activity Database

Hellinger, Petr; Trávníček, Pavel; Kasper, J. C.; Lazarus, A. J.

2006-01-01

Roč. 33, č. 9 (2006), L09101/1-L09101/4 ISSN 0094-8276 R&D Projects: GA AV ČR(CZ) IAA3042403 Grant - others:ESA(XE) PECS 98024; NASA (US) NAG-10915 Institutional research plan: CEZ:AV0Z30420517 Keywords : proton temperature anisotropy * solar wind * in situ observations Subject RIV: DG - Athmosphere Sciences, Meteorology Impact factor: 2.602, year: 2006

77 FR 46764 - Clinical Studies of Safety and Effectiveness of Orphan Products Research Project Grant (R01)

Science.gov (United States)

2012-08-06

...] Clinical Studies of Safety and Effectiveness of Orphan Products Research Project Grant (R01) AGENCY: Food... per year. B. Research Objectives The goal of FDA's OPD grant program is to support the clinical... (OPD) grant program. The goal of FDA's OPD grant program is to support the clinical development of...

Grant Administrator | IDRC - International Development Research ...

International Development Research Centre (IDRC) Digital Library (Canada)

Job Summary A Grant Administrator is responsible to provide financial and ... and financial aspects of the project, as well as, country and institutional risks are ... and financial project data in the grants and project management system of IDRC.

“Spirit, Soul and Body in Nag Hammadi Literature: Distinguishing Anthropological Schemes in Valentinian, Sethian, Hermetic and Thomasine Texts”

NARCIS (Netherlands)

Roig Lanzillotta, Fernando

2017-01-01

A close analysis of the views on man in the Nag Hammadi texts reflects that the tripartite pattern distinguishing three elements in the human being (intellect or spirit, soul and body), even if majoritarian, is not the only one at work in the corpus: there is also a group of texts reflecting rather

Outline of Summary Meeting on Nuclear Fusion Research by Grant-in-Aid (1986-1989) by Monbusho

International Nuclear Information System (INIS)

Ishino, Shiori; Nakazawa, Masaharu; Iguchi, Tetsuo

1990-01-01

The Summary Meeting on Nuclear Fusion Research by Grant-in-Aid (1986∼1989) of Monbusho was held on Jan. 30∼Feb. 1, 1989 at Gakushi-kaikan in Tokyo. About 300 papers were presented on the research activities as well as some special topics. (author)

Preparation, characterization and activity evaluation of p-n junction photocatalyst p-CaFe2O4/n-Ag3VO4 under visible light irradiation

International Nuclear Information System (INIS)

Chen Shifu; Zhao Wei; Liu Wei; Zhang Huaye; Yu Xiaoling; Chen Yinghao

2009-01-01

p-n junction photocatalyst p-CaFe 2 O 4 /n-Ag 3 VO 4 was prepared by ball milling Ag 3 VO 4 in H 2 O doped with p-type CaFe 2 O 4 . The structural and optical properties of the photocatalyst were characterized by X-ray powder diffraction (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) and UV-vis diffuse reflection spectrum (DRS). The photocatalytic activity was evaluated by photocatalytic degradation of methylene blue (MB) under visible light irradiation. The results showed that the photocatalytic activity of the p-CaFe 2 O 4 /n-Ag 3 VO 4 was higher than that of Ag 3 VO 4 . When the amount of doped p-CaFe 2 O 4 was 2.0 wt.% and the p-CaFe 2 O 4 /n-Ag 3 VO 4 was ball milled for 12 h, the photocatalytic degradation efficiency was 85.4%. Effect of ball milling time on the photocatalytic activity of the photocatalyst was also investigated. The mechanisms of the increase in the photocatalytic activity were discussed by the p-n junction principle.

Bursaries, writing grants and fellowships: a strategy to develop research capacity in primary health care

Directory of Open Access Journals (Sweden)

Farmer Elizabeth A

2007-04-01

Full Text Available Abstract Background General practitioners and other primary health care professionals are often the first point of contact for patients requiring health care. Identifying, understanding and linking current evidence to best practice can be challenging and requires at least a basic understanding of research principles and methodologies. However, not all primary health care professionals are trained in research or have research experience. With the aim of enhancing research skills and developing a research culture in primary health care, University Departments of General Practice and Rural Health have been supported since 2000 by the Australian Government funded 'Primary Health Care Research Evaluation and Development (PHCRED Strategy'. A small grant funding scheme to support primary health care practitioners was implemented through the PHCRED program at Flinders University in South Australia between 2002 and 2005. The scheme incorporated academic mentors and three types of funding support: bursaries, writing grants and research fellowships. This article describes outcomes of the funding scheme and contributes to the debate surrounding the effectiveness of funding schemes as a means of building research capacity. Methods Funding recipients who had completed their research were invited to participate in a semi-structured 40-minute telephone interview. Feedback was sought on acquisition of research skills, publication outcomes, development of research capacity, confidence and interest in research, and perception of research. Data were also collected on demographics, research topics, and time needed to complete planned activities. Results The funding scheme supported 24 bursaries, 11 writing grants, and three research fellows. Nearly half (47% of all grant recipients were allied health professionals, followed by general practitioners (21%. The majority (70% were novice and early career researchers. Eighty-nine percent of the grant recipients were

Magnetic component of narrowband ion cyclotron waves in the auroral zone

Czech Academy of Sciences Publication Activity Database

Santolík, Ondřej; Pickett, J. S.; Gurnett, D. A.; Storey, L. R. O.

2002-01-01

Roč. 107, A12, 1444 (2002), s. SMP 17-1-17-14, doi: 10.1029/2001JA000146 ISSN 0148-0227 R&D Projects: GA ČR GA205/01/1064 Grant - others:NASA(US) NAG5-7943 Institutional research plan: CEZ:AV0Z3042911; CEZ:MSM 113200004 Keywords : proton-cyclotron frequency * plasma wave instrument * cyclotron waves Subject RIV: DG - Athmosphere Sciences, Meteorology Impact factor: 2.245, year: 2002

A microscopic and nanoscopic view of storm-time chorus

Czech Academy of Sciences Publication Activity Database

Santolík, Ondřej; Gurnett, D. A.; Pickett, J. S.; Parrot, M.; Cornilleau-Wehrlin, N.

2004-01-01

Roč. 31, L02801 (2004), s. 1-5, doi: 10.1029/2003GL018757, 2004 ISSN 0094-8276 R&D Projects: GA MŠk ME 650; GA ČR GA202/03/0832 Grant - others: NASA (US) NAG5-7943 Institutional research plan: CEZ:AV0Z3042911; CEZ:MSM 113200004 Keywords : magnetospheric physics * plasma waves and instabilities * ring current Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 2.378, year: 2004

32 CFR 22.310 - Statutes concerning certain research, development, and facilities construction grants.

Science.gov (United States)

2010-07-01

... higher education for the performance of research and development or for the construction of research or... for research and development, or of a grant for the construction of research or other facilities... research and development or for the construction of research or other facilities are to be awarded to...

22 CFR 63.4 - Grants to foreign participants to lecture, teach, and engage in research.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Grants to foreign participants to lecture, teach, and engage in research. 63.4 Section 63.4 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES PAYMENTS TO AND ON BEHALF OF PARTICIPANTS IN THE INTERNATIONAL EDUCATIONAL AND CULTURAL...

Spin rate distribution of small asteroids

Czech Academy of Sciences Publication Activity Database

Pravec, Petr; Harris, A. W.; Vokrouhlický, D.; Warner, B. D.; Kušnirák, Peter; Hornoch, Kamil; Pray, D. P.; Higgins, D.; Oey, J.; Galád, Adrián; Gajdoš, Š.; Kornoš, L.; Világi, J.; Husárik, M.; Krugly, Yu. N.; Shevchenko, V. G.; Chiorny, V. G.; Gaftonyuk, N. M.; Cooney jr., W. R.; Gross, J.; Terrell, D.; Stephens, R.; Dyvig, R.; Reddy, V.; Ries, J.G.; Colas, F.; Lecacheux, J.; Durkee, R.; Masi, G.; Koff, R.; Goncalves, R.

2008-01-01

Roč. 197, č. 2 (2008), s. 497-504 ISSN 0019-1035 R&D Projects: GA ČR(CZ) GA205/05/0604 Grant - others: NASA (US) NAG5-13244; NASA (US) NNG06GI32G; VEGA(SK) 1/3074/06; VEGA(SK) 1/3067/06; VEGA(SK) 2/7009/27 Institutional research plan: CEZ:AV0Z10030501 Keywords : asteroids rotation * photometry * near-Earth objects Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 3.268, year: 2008

75 FR 47602 - Clinical Studies of Safety and Effectiveness of Orphan Products Research Project Grant (R01)

Science.gov (United States)

2010-08-06

...] Clinical Studies of Safety and Effectiveness of Orphan Products Research Project Grant (R01) AGENCY: Food... (OPD) grant program. The goal of FDA's OPD grant program is to support the clinical development of... product will be superior to the existing therapy. FDA provides grants for clinical studies on safety and...

ROSAT: X ray survey of compact groups

NARCIS (Netherlands)

van Gorkom, Jacqueline

1993-01-01

This is the final technical report on grant NAG5-1954, which was awarded under the NASA ROSAT Guest Investigator Program to Columbia University. This grant was awarded for a number of projects on two rather different topics: (1) an x-ray survey of compact groups of galaxies; and (2) the fate of gas

10 CFR 600.381 - Special provisions for Small Business Innovation Research Grants.

Science.gov (United States)

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Special provisions for Small Business Innovation Research... Organizations Additional Provisions § 600.381 Special provisions for Small Business Innovation Research Grants. (a) General. This section contains provisions applicable to the Small Business Innovation Reserach...

Spatio-temporal structure of storm-time chorus

Czech Academy of Sciences Publication Activity Database

Santolík, Ondřej; Gurnett, D. A.; Pickett, J. S.; M. Parrot, M.; Cornilleau-Wehrlin, N.

2003-01-01

Roč. 108, A7 (2003), s. 7-1-7-14, doi:10.1029/2002JA009791, 2003 ISSN 0148-0227 R&D Projects: GA ČR GA202/03/0832; GA MŠk ME 650 Grant - others:NASA(US) NAG5-9974 Institutional research plan: CEZ:AV0Z3042911; CEZ:MSM 113200004 Keywords : storm -time chorus emissions * whistler mode * propagation analysis Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 2.992, year: 2003

Enzymatic synthesis of new C-6-acylated derivatives of NAG-thiazoline and evaluation of their inhibitor activities towards fungal beta-N-acetylhexosaminidase

Czech Academy of Sciences Publication Activity Database

Krejzová, Jana; Šimon, Petr; Vavříková, Eva; Slámová, Kristýna; Pelantová, Helena; Riva, S.; Spiwok, V.; Křen, Vladimír

2013-01-01

Roč. 87, MAR (2013), s. 128-134 ISSN 1381-1177 R&D Projects: GA ČR(CZ) GAP207/11/0629; GA MŠk OC09045; GA MŠk(CZ) LD13042 Institutional support: RVO:61388971 Keywords : NAG-thiazoline * Lipase * Vinyl ester Subject RIV: CE - Biochemistry Impact factor: 2.745, year: 2013

Segue: A Spectroscopic Survey of 240,000 Stars With g = 14-20

Science.gov (United States)

2009-05-01

Departamento de Fisica y Astronomia , Facultad de Ciencias, Universidad de Valparaiso, Valparaiso, Chile 30 Department of Physics and Astronomy, Austin Peay...types. The sample spectra are plotted with flux in units of 10−17 erg cm−2 s−1 Å on the y -axis versus wavelength in Å on the x-axis. If more than one...the University of Washington. C. Allende Prieto acknowledges support from NASA grants NAG 5-13057 and NAG 5-13147. T. C. Beers, Y . S. Lee, and S

$200,000 Grants Awarded to CCR Researchers for HIV/AIDS Studies | Poster

Science.gov (United States)

By Nancy Parrish, Staff Writer Earlier this year, the Office of AIDS Research (OAR) awarded two, two-year grants of $200,000 each to Anu Puri, Ph.D., and Robert Blumenthal, Ph.D., both of the Center for Cancer Research (CCR) Nanobiology Program, and to Eric Freed, Ph.D., of the HIV Drug Resistance Program, for their research on potential new treatments for HIV.

Sun Grant Initiative Regional Biomass Feedstock Partnership Competitive Grants Program

Energy Technology Data Exchange (ETDEWEB)

Owens, Vance [South Dakota State Univ., Brookings, SD (United States). North Central Regional Sun Grant Center

2016-12-30

The Sun Grant Initiative partnered with the US Department of Energy (DOE) in 2008 to create the Regional Biomass Feedstock Partnership Competitive Grants Program. The overall goal of this project was to utilize congressionally directed funds to leverage the North Central Regional Sun Grant’s Competitive Grant program at South Dakota State University (SDSU) to address key issues and research gaps related to development of the bioeconomy. Specific objectives of this program were to: 1. Identify research projects through a Regional Competitive Grants program that were relevant to the sustainable production, harvest, transport, delivery, and processing/conversion of cost-competitive, domestically grown biomass. 2. Build local expertise and capacity at the North Central Regional Sun Grant Center at SDSU through an internal selection of key bioenergy research projects. To achieve these, three nationwide Request for Applications (RFA) were developed: one each in 2008, 2009, and 2010. Internal, capacity building projects at SDSU were also selected during each one of these RFAs. In 2013 and 2015, two additional Proof of Concept RFAs were developed for internal SDSU projects. Priority areas for each RFA were 1) Biomass feedstock logistics including biomass harvesting, handling, transportation, storage, and densification; 2) Sustainable biomass feedstock production systems including biomass crop development, production, and life-cycle analysis; 3) Biomass production systems that optimize biomass feedstock yield and economic return across a diverse landscape while minimizing negative effects on the environment and food/feed production; and 4) Promotion of knowledge-based economic development in science and technology and to advance commercialization of inventions that meet the mission of the Sun Grant Initiative. A total of 33 projects were selected for funding through this program. Final reports for each of these diverse projects are included in this summary report

Chorus source properties that produce time shifts and frequency range differences observed on different Cluster spacecraft

Czech Academy of Sciences Publication Activity Database

Chum, Jaroslav; Santolík, Ondřej; Breneman, A. W.; Kletzing, C. A.; Gurnett, D. A.; Pickett, J. S.

2007-01-01

Roč. 112, A6 (2007), A06206/1-A06206/10 ISSN 0148-0227 R&D Projects: GA AV ČR IAA301120601 Grant - others:ESA(XE) PECS 98025; NASA (US) NAG5-9974; NASA (US) NNG04GB98G Institutional research plan: CEZ:AV0Z30420517 Keywords : Magnetospheric physics (Waves in plasma, Wave propagation) * Space plasma physics (Wave-particle interactions, Waves and instabilities) Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 2.953, year: 2007

Supporting public involvement in research design and grant development: a case study of a public involvement award scheme managed by a National Institute for Health Research (NIHR) Research Design Service (RDS).

Science.gov (United States)

Boote, Jonathan D; Twiddy, Maureen; Baird, Wendy; Birks, Yvonne; Clarke, Clare; Beever, Daniel

2015-10-01

It is good practice for the public to be involved in developing health research. Resources should be available for researchers to fund the involvement of the public in the development of their grants. To describe a funding award scheme to support public involvement in grant development, managed by an NIHR Research Design Service (RDS). Case examples of how the award contributed to successful grant applications and findings from a recent evaluation of the scheme are presented. A case study of resource provision to support public involvement activities in one region of England. University and NHS-based researchers, and members of the public. Between 2009 and 2012, the RDS approved 45 public involvement funding awards (totalling nearly £19,000). These awards contributed to 27 submitted applications at the time of writing, of which 11 were successful (totalling over £7.5 million). The evaluation revealed difficulties encountered by some researchers when involving the public in grant development, which led to suggestions about how the scheme could be improved. This award scheme represents an efficient method of providing researchers with resources to involve the public in grant development and would appear to represent good value for money. © 2013 John Wiley & Sons Ltd.

42 CFR 86.12 - Application for a grant.

Science.gov (United States)

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Application for a grant. 86.12 Section 86.12 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES GRANTS FOR EDUCATION PROGRAMS IN OCCUPATIONAL SAFETY AND HEALTH Occupational Safety and Health Training Grants §...

Drifting field-aligned density structures in the night-side polar cap

Czech Academy of Sciences Publication Activity Database

Santolík, Ondřej; Persoon, A. M.; Gurnett, D. A.; Décréau, P. M. E.; Pickett, J. S.; Maršálek, O.; Maksimovic, M.; Cornilleau-Wehrlin, N.

2005-01-01

Roč. 32, - (2005), L06106-1 ISSN 0094-8276 R&D Projects: GA ČR(CZ) GA202/03/0832; GA MŠk ME 650; GA MŠk 1P05ME811 Grant - others: NASA (US) NAG5-9974; NASA (US) NNG04GB98G; NSF(US) 0307319; ESA PECS(XE) 98025 Institutional research plan: CEZ:AV0Z30420517 Keywords : Magnetospheric Physics * Plasma convection * Plasma waves and instabilities * Polar cap phenomena * Magnetospheric configuration and dynamics Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 2.491, year: 2005

On the generation of solitary waves observed by Cluster in the near-Earth magnetosheath

Czech Academy of Sciences Publication Activity Database

Pickett, J. S.; Chen, L. J.; Kahler, S. W.; Santolík, Ondřej; Goldstein, M. L.; Lavraud, B.; Décréau, P. M. E.; Kessel, R.; Lucek, E.; Lakhina, G. S.; Tsurutani, B. T.; Gurnett, D. A.; Cornilleau-Wehrlin, N.; Fazakerley, A.; Rème, H.; Balogh, A.

2005-01-01

Roč. 12, - (2005), s. 181-193 ISSN 1023-5809 R&D Projects: GA MŠk(CZ) ME 650; GA ČR(CZ) GA202/03/0832; GA MŠk(CZ) 1P05ME811 Grant - others: NASA GSFC(US) NAG5-9974; NASA GSFC(US) NNG04GB98G; NSF(US) ATM 03-27450; NSF(US) 0307319; ESA PECS(XE) 98025 Institutional research plan: CEZ:AV0Z30420517 Keywords : solitary waves * Cluster * near-Earth magnetosheath Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.464, year: 2005

MO and DA on the SWIE Instrument on the Wind Spacecraft

Science.gov (United States)

Lazarus, Alan J.

2002-01-01

The construction of the Faraday Cup portion of the SWIE instrument on the Wind spacecraft, participation in Mission Operations, and Data Analysis (MO and DA) of observations of the solar wind has been supported by a sequence of grants. This 'final' Report represents work done on Mission Operations and Data Analysis for the Faraday Cup portion of the SWE. The work reported here was supported under NASA Grant NAG5-7359 (OSP 6701100) from June 1998 to October 2001. It should be noted that this work is continuing under NASA Grant NAG-10915, and therefore this report is 'final' only in the sense that the Grant has changed its number; a future report will cover the entire period of work. We have two types of obligations under these contracts: (1) To provide and assure the validity of "Key Parameters" which describe the basic properties of the solar wind on a daily basis. We have provided our 92 second observations daily via plots and parameters available from our Web site: http://web.mit.edu/space/www/wind/wind.html (2). To carry out scientific studies based on our observations. To document the extent of our research, we are including below a list of publications and presentations related to this project. The observations from Wind have made a major contribution to the study of the solar wind, and have every indication of continuing to do so.

Multidisciplinary Mentoring Programs to Enhance Junior Faculty Research Grant Success.

Science.gov (United States)

Freel, Stephanie A; Smith, Paige C; Burns, Ebony N; Downer, Joanna B; Brown, Ann J; Dewhirst, Mark W

2017-10-01

Junior faculty face challenges in establishing independent research careers. Declining funding combined with a shift to multidisciplinary, collaborative science necessitates new mentorship models and enhanced institutional support. Two multidisciplinary mentorship programs to promote grant success for junior faculty were established at the Duke University School of Medicine beginning in 2011. These four-month programs-the Path to Independence Program (PtIP) for National Institutes of Health (NIH) R applicants and the K Club for NIH K applicants-use multiple senior faculty mentors and professional grant-writing staff to provide a 20-hour joint curriculum comprising a series of lectures, hands-on workshops, career development counseling, peer groups, and an internal study section. In March 2016, the authors analyzed the success rate for all NIH grants submitted by participants since program enrollment. In a 2015 postprogram survey, participants rated their feelings of support and competency across six skill factors. From October 2011 to March 2016, the programs engaged 265 senior faculty mentors, 145 PtIP participants, and 138 K Club participants. Success rates for NIH grant applications were 28% (61 awards/220 decisions) for PtIP participants-an increase over the 2010 Duke University junior faculty baseline of 11%-and 64% (38/59) for K Club participants. Respondents reported significantly increased feelings of support and self-ratings for each competency post program. The authors plan to expand the breadth of both the mentorship pool and faculty served. Broad implementation of similar programs elsewhere could bolster success, satisfaction, and retention of junior faculty investigators.

A genre analysis of English language research grant proposal abstracts in Chile

OpenAIRE

Matzler, Pascal P

2014-01-01

The writing of English-language research genres represent a challenging task for non-native-speaker researchers. Grant proposals, in particular, are a high-stakes genre that will greatly influence a researcher’s career development opportunities; however, novice researchers are faced with an urgent lack of publicly available exemplars or teaching materials for this genre. The present study attempts to address this issue by means of Swalesian genre analysis. First, a move system analysis is app...

N-acetylglutamate synthase deficiency: an insight into the genetics, epidemiology, pathophysiology, and treatment

Directory of Open Access Journals (Sweden)

Caldovic L

2011-08-01

Full Text Available Nicholas Ah Mew, Ljubica CaldovicCenter for Genetic Medicine Research, Children’s Research Institute, Children’s National Medical Center, Washington DC, USAAbstract: The conversion of ammonia into urea by the human liver requires the coordinated function of the 6 enzymes and 2 transporters of the urea cycle. The initial and rate-limiting enzyme of the urea cycle, carbamylphosphate synthetase 1 (CPS1, requires an allosteric activator, N-acetylglutamate (NAG. The formation of this unique cofactor from glutamate and acetyl Coenzyme-A is catalyzed by N-acetylglutamate synthase (NAGS. An absence of NAG as a consequence of NAGS deficiency may compromise flux through CPS1 and result in hyperammonemia. The NAGS gene encodes a 528-amino acid protein, consisting of a C-terminal catalytic domain, a variable segment, and an N-terminal mitochondrial targeting signal. Only 22 mutations in the NAGS gene have been reported to date, mostly in the catalytic domain. NAGS is primarily expressed in the liver and intestine. However, it is also surprisingly expressed in testis, stomach and spleen, and during early embryonic development at levels not concordant with the expression of other urea cycle enzymes, CPS1, or ornithine transcarbamylase. The purpose of NAGS expression in these tissues, and its significance to NAGS deficiency is as yet unknown. Inherited NAGS deficiency is the rarest of the urea cycle disorders, and we review the currently reported 34 cases. Treatment of NAGS deficiency with N-carbamyglutamate, a stable analog of NAG, can restore deficient urea cycle function and normalize blood ammonia in affected patients.Keywords: urea cycle, urea cycle disorder, N-acetyl-L-glutamate, N-acetylglutamate synthase, hyperammonemia, N-carbamyl-L-glutamate

A 25-year analysis of the American College of Gastroenterology research grant program: factors associated with publication and advancement in academics.

Science.gov (United States)

Crockett, Seth D; Dellon, Evan S; Bright, Stephanie D; Shaheen, Nicholas J

2009-05-01

The American College of Gastroenterology (ACG) has awarded research grants for 25 years. We assessed the characteristics of grant recipients, their current academic status, and the likelihood of publication resulting from the grant. Demographic data, the year and amount of award, title of project, and recipient's institution were extracted from ACG databases. Using ACG reports and medical literature search engines, we assessed publication based on grant-funded research, as well as career publication record. We also determined the current position of awardees. A similar analysis was performed for recipients of junior investigator awards. A total of 396 clinical research awards totaling $5,374,497 ($6,867,937 in 2008 dollars) were awarded to 341 recipients in the 25 years between 1983 and 2008. The most commonly funded areas of research were endoscopy (22% of awards) and motility/functional disorders (21%). At least one peer-reviewed publication based on grant-funded research occurred with 255 of the 368 awards (69%) for 1983-2006 [corrected]. Higher award value was associated with subsequent publication. Of the 313 awardees over the same period, 195 (62%) are currently in academic positions [corrected]. Factors associated with staying in academics included higher award value (P academics. Overall, the mean cost in grant dollars per published paper based on the research was $14,875. The majority of ACG grant recipients published the results of their research and remained in academics. Higher amount of award, holding an advanced degree, and publication were associated with careers in academics. The ACG research grant award program is an important engine of investigation, publication, and academic career development in the field of gastroenterology.

Evaluation of NSF's Program of Grants and Vertical Integration of Research and Education in the Mathematical Sciences (VIGRE)

Science.gov (United States)

National Academies Press, 2009

2009-01-01

In 1998, the National Science Foundation (NSF) launched a program of Grants for Vertical Integration of Research and Education in the Mathematical Sciences (VIGRE). These grants were designed for institutions with PhD-granting departments in the mathematical sciences, for the purpose of developing high-quality education programs, at all levels,…

42 CFR 51b.605 - How will grant applications be evaluated and the grants awarded?

Science.gov (United States)

2010-10-01

... HUMAN SERVICES GRANTS PROJECT GRANTS FOR PREVENTIVE HEALTH SERVICES Grants for Research, Demonstrations... has potential to directly benefit the national venereal disease control effort? (2) Are the project...

Developing research and recruitment while fostering stakeholder engagement in a National Institutes of Mental Health-funded Interventions and Practice Research Infrastructure Programs grant for depression.

Science.gov (United States)

Stirman, Shannon Wiltsey; Goldstein, Lizabeth A; Wrenn, Glenda; Barrett, Marna; Gibbons, Mary Beth Connolly; Casiano, Delane; Thompson, Donald; Green, Patricia P; Heintz, Laura; Barber, Jacques P; Crits-Christoph, Paul

2010-01-01

In the context of a National Institutes of Mental Health-funded Interventions and Practice Research Infrastructure Programs (IP-RISP) grant for the treatment of depression, a partnership was developed between a community mental health organization and a team of researchers. This paper describes the collaborative process, key challenges, and strategies employed to meet the goals of the first phase of the grant, which included development of a working and sustainable partnership and building capacity for recruitment and research. This paper was developed through the use of qualitative interviews and discussion with a variety of IP-RISP partners. Communication with multiple stakeholders through varied channels, feedback from stakeholders on research procedures, and employing a research liaison at the clinic have been key strategies in the first phase of the grant. The strategies we employed allowed multiple stakeholders to contribute to the larger mission of the IP-RISP and helped to establish an ongoing research program within the mental health organization.

Write More Articles, Get More Grants: The Impact of Department Climate on Faculty Research Productivity.

Science.gov (United States)

Sheridan, Jennifer; Savoy, Julia N; Kaatz, Anna; Lee, You-Geon; Filut, Amarette; Carnes, Molly

2017-05-01

Many studies find that female faculty in academic medicine, science, and engineering experience adverse workplace climates. This study longitudinally investigates whether department climate is associated with future research productivity and whether the associations are stronger for female than male faculty. Two waves of a faculty climate survey, institutional grant records, and publication records were collected for 789 faculties in academic medicine, science, and engineering at the University of Wisconsin-Madison between 2000 and 2010. Research productivity was measured as Number of Publications and Number of Grants awarded, and department climate was measured with scales for professional interactions, department decision-making practices, climate for underrepresented groups, and work/life balance. Ordinary least squares and negative binomial regression methods were used to assess gender differences in productivity, influences of department climate on productivity, and gender differences in effects of climate on productivity. Female faculty published fewer articles and were awarded fewer grants in the baseline period, but their productivity did not differ from male faculty on these measures in subsequent years. Number of Publications was positively affected by professional interactions, but negatively affected by positive work/life balance. Number of Grants awarded was positively affected by climate for underrepresented groups. These main effects did not differ by gender; however, some three-way interactions illuminated how different aspects of department climate affected productivity differently for men and women in specific situations. In perhaps the first study to assess the longitudinal impact of department climate on faculty research productivity, positive department climate is associated with significantly greater productivity for all faculty-women and men. However, some positive aspects of climate (specifically, work/life balance) may be associated with

Educators' Use of Research and Other Evidence within Local Grant Foundation Applications

Science.gov (United States)

Malin, Joel R.

2016-01-01

In this study, educators' requests for foundation grant funding to purchase desired educational materials or services were examined. Specifically, this study sought to review to what extent, and in what manner, educators utilize research and other forms of evidence to support their decision making. Data analysis revealed several themes. Although…

Writing Cancer Grant Applications | Center for Cancer Research

Science.gov (United States)

This course focuses on how to write clear and persuasive grant applications. The purpose is to increase the quality of your grant application by successfully communicating scientific data and ideas. Emphasis is placed on how to use the title abstract and introduction sections to draw in reviewers and how to write an organized and focused proposal using specific scientific aims.

Proteomic analysis of proteins differentially expressed in conidia and mycelium of the entomopathogenic fungus Aschersonia placenta

Czech Academy of Sciences Publication Activity Database

Qiu, J.; Su, Y.; Gelbič, Ivan; Qiu, Y.; Xie, X.; Guan, X.

2012-01-01

Roč. 58, č. 12 (2012), s. 1327-1334 ISSN 0008-4166 Grant - others:National Natural Science Foundation of China(CN) 30500005; National Natural Science Foundation of China(CN) 31070026; National Natural Science Foundation of China(CN) 31170025; Fujian Province University(CN) JK2011013; Fujian Provincial Science Foundation(CN) 2010J06007; Chinese National Programs(CN) 2011AA10A203; Fujian Provincial Science Foundation(CN) 0b08b005 Institutional research plan: CEZ:AV0Z50070508 Keywords : entomopathogenic fungus * Aschersonia placenta * fungal developmental stages Subject RIV: CE - Biochemistry Impact factor: 1.199, year: 2012

Nonlinear decay of foreshock Langmuir waves in the presence of plasma inhomogeneities: Theory and Cluster observations

Czech Academy of Sciences Publication Activity Database

Souček, Jan; Krasnoselskikh, V.; Dudok de Wit, T.; Pickett, J.; Kletzing, C.

2005-01-01

Roč. 110, A8 (2005), A08102/1-A08102/10 ISSN 0148-0227 R&D Projects: GA MŠk ME 650; GA ČR GA202/03/0832 Grant - others:CNRS(FR) PICS 1175; ESA PRODEX(XE) 14529; NSF(US) 0307319; NASA (US) NAG5-9974; NASA (US) NNG04GB98G; European Comunity(XE) HPRN-CT-2001-00314 Institutional research plan: CEZ:AV0Z30420517 Keywords : plasma waves * kinetic waves and instabilities * foreshock * solar wind Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 2.784, year: 2005

The relationship between auroral hiss at high altitudes over the polar caps and the substorm dynamics of aurora

Czech Academy of Sciences Publication Activity Database

Titova, E. E.; Yahnin, A. G.; Santolík, Ondřej; Gurnett, D. A.; Jiříček, František; Rauch, J. L.; Lefeuvre, F.; Frank, L. A.; Sigwarth, J. B.; Mogilevsky, M. M.

2005-01-01

Roč. 23, - (2005), s. 2117-2128 ISSN 0992-7689 R&D Projects: GA AV ČR IAA3042201; GA ČR GA205/03/0953; GA MŠk ME 650; GA ČR GA202/03/0832; GA MŠk 1P05ME811 Grant - others:ESA PECS(XE) 98025; INTAS(RU) 03-51-4132; NATO(XE) PST.GLG980041; NASA (US) NAG5-7943 Institutional research plan: CEZ:AV0Z30420517 Keywords : Magnetospheric physics (Auroral phenomena, Plasma waves and instabilities, Storms and substorms) Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.450, year: 2005

Surveys of current status in biomedical science grant review: funding organisations' and grant reviewers' perspectives

DEFF Research Database (Denmark)

Schroter, Sara; Groves, Trish; Højgaard, Liselotte

2010-01-01

The objectives of this research were (a) to describe the current status of grant review for biomedical projects and programmes from the perspectives of international funding organisations and grant reviewers, and (b) to explore funders' interest in developing uniform requirements for grant review...

Algorithms for parallel and vector computations

Science.gov (United States)

Ortega, James M.

1995-01-01

This is a final report on work performed under NASA grant NAG-1-1112-FOP during the period March, 1990 through February 1995. Four major topics are covered: (1) solution of nonlinear poisson-type equations; (2) parallel reduced system conjugate gradient method; (3) orderings for conjugate gradient preconditioners, and (4) SOR as a preconditioner.

Strategies to Prevent or Reduce Gender Bias in Peer Review of Research Grants: A Rapid Scoping Review.

Directory of Open Access Journals (Sweden)

Andrea C Tricco

Full Text Available To review the literature on strategies implemented or identified to prevent or reduce gender bias in peer review of research grants.Studies of any type of qualitative or quantitative design examining interventions to reduce or prevent gender bias during the peer review of health-related research grants were included. Electronic databases including MEDLINE, EMBASE, Education Resources Information Center (ERIC, PsycINFO, Joanna Briggs, the Cochrane Library, Evidence Based Medicine (EBM Reviews, and the Campbell Library were searched from 2005 to April 2016. A search for grey (i.e., difficult to locate or unpublished literature was conducted and experts in the field were consulted to identify additional potentially relevant articles. Two individuals screened titles and abstracts, full-text articles, and abstracted data with discrepancies resolved by a third person consistently.After screening 5524 citations and 170 full-text articles, one article evaluating gender-blinding of grant applications using an uncontrolled before-after study design was included. In this study, 891 applications for long-term fellowships in 2006 were included and 47% of the applicants were women. These were scored by 13 peer reviewers (38% were women. The intervention included eliminating references to gender from the applications, letters of recommendations, and interview reports that were sent to the committee members for evaluation. The proportion of successful applications led by women did not change with gender-blinding, although the number of successful applications that were led by men increased slightly.There is limited research on interventions to mitigate gender bias in the peer review of grants. Only one study was identified and no difference in the proportion of women who were successful in receiving grant funding was observed. Our results suggest that interventions to prevent gender bias should be adapted and tested in the context of grant peer review to

Write More Articles, Get More Grants: The Impact of Department Climate on Faculty Research Productivity

Science.gov (United States)

Savoy, Julia N.; Kaatz, Anna; Lee, You-Geon; Filut, Amarette; Carnes, Molly

2017-01-01

Abstract Background: Many studies find that female faculty in academic medicine, science, and engineering experience adverse workplace climates. This study longitudinally investigates whether department climate is associated with future research productivity and whether the associations are stronger for female than male faculty. Method: Two waves of a faculty climate survey, institutional grant records, and publication records were collected for 789 faculties in academic medicine, science, and engineering at the University of Wisconsin-Madison between 2000 and 2010. Research productivity was measured as Number of Publications and Number of Grants awarded, and department climate was measured with scales for professional interactions, department decision-making practices, climate for underrepresented groups, and work/life balance. Ordinary least squares and negative binomial regression methods were used to assess gender differences in productivity, influences of department climate on productivity, and gender differences in effects of climate on productivity. Results: Female faculty published fewer articles and were awarded fewer grants in the baseline period, but their productivity did not differ from male faculty on these measures in subsequent years. Number of Publications was positively affected by professional interactions, but negatively affected by positive work/life balance. Number of Grants awarded was positively affected by climate for underrepresented groups. These main effects did not differ by gender; however, some three-way interactions illuminated how different aspects of department climate affected productivity differently for men and women in specific situations. Conclusions: In perhaps the first study to assess the longitudinal impact of department climate on faculty research productivity, positive department climate is associated with significantly greater productivity for all faculty—women and men. However, some positive aspects of climate

A community translational research pilot grants program to facilitate community--academic partnerships: lessons from Colorado's clinical translational science awards.

Science.gov (United States)

Main, Deborah S; Felzien, Maret C; Magid, David J; Calonge, B Ned; O'Brien, Ruth A; Kempe, Allison; Nearing, Kathryn

2012-01-01

National growth in translational research has increased the need for practical tools to improve how academic institutions engage communities in research. One used by the Colorado Clinical and Translational Sciences Institute (CCTSI) to target investments in community-based translational research on health disparities is a Community Engagement (CE) Pilot Grants program. Innovative in design, the program accepts proposals from either community or academic applicants, requires that at least half of requested grant funds go to the community partner, and offers two funding tracks: One to develop new community-academic partnerships (up to $10,000), the other to strengthen existing partnerships through community translational research projects (up to $30,000). We have seen early success in both traditional and capacity building metrics: the initial investment of $272,742 in our first cycle led to over $2.8 million dollars in additional grant funding, with grantees reporting strengthening capacity of their community- academic partnerships and the rigor and relevance of their research.

Implementing falls prevention research into policy and practice: an overview of a new National Health and Medical Research Council Partnership Grant.

Science.gov (United States)

Lord, Stephen R; Delbaere, Kim; Tiedemann, Anne; Smith, Stuart T; Sturnieks, Daina L

2011-06-01

Preventing falls and fall-related injuries among older people is an urgent public health challenge. This paper provides an overview of the background to and research planned for a 5-year National Health and Medical Research Council Partnership Grant on implementing falls prevention research findings into policy and practice. This program represents a partnership between key Australian falls prevention researchers, policy makers and information technology companies which aims to: (1) fill gaps in evidence relating to the prevention of falls in older people, involving new research studies of risk factor assessment and interventions for falls prevention; (2) translate evidence into policy and practice, examining the usefulness of new risk-identification tools in clinical practice; and (3) disseminate evidence to health professionals working with older people, via presentations, new evidence-based guidelines, improved resources and learning tools, to improve the workforce capacity to prevent falls and associated injuries in the future.

Urine Levels of Defensin α1 Reflect Kidney Injury in Leptospirosis Patients

Directory of Open Access Journals (Sweden)

Haorile Chagan-Yasutan

2016-09-01

Full Text Available Leptospirosis is a zoonotic disease whose severe forms are often accompanied by kidney dysfunction. In the present study, urinary markers were studied for potential prediction of disease severity. Urine samples from 135 patients with or without leptospirosis at San Lazaro Hospital, the Philippines, were analyzed. Urine levels of defensin α1 (uDA1 were compared with those of neutrophil gelatinase-associated lipocalin (uNGAL and N-acetyl-β-d-glucosidase (uNAG. Serum creatinine (Cr was used as a marker of kidney injury. The levels of uDA1/Cr, uNGAL/Cr, and uNAG/Cr were positive in 46%, 90%, and 80% of leptospirosis patients, and 69%, 70%, and 70% of non-leptospirosis patients, respectively. In leptospirosis patients, the correlation of uDA1/Cr, uNGAL/Cr and uNAG/Cr levels with serum Cr were r = 0.3 (p < 0.01, r = 0.29 (p < 0.01, and r = 0.02 (p = 0.81, respectively. uDA1/Cr levels were correlated with uNGAL/Cr levels (r = 0.49, p < 0.01 and uNAG/Cr levels (r = 0.47, p < 0.0001 in leptospirosis patients. These findings suggest that uDA1, uNGAL, and uNAG were elevated in leptospirosis patients and reflected various types of kidney damage. uDA1 and uNGAL can be used to track kidney injury in leptospirosis patients because of their correlation with the serum Cr level.

The interactive influence of water chemistry and nanoparticle characteristics in determining the environmental fate of metal-based nanoparticles: a case of nAg and nZnO

CSIR Research Space (South Africa)

Thwala, M

2014-09-01

Full Text Available . The NP concentration (number/mL) in 100HM remained relatively higher than in 50HM, more so for nAg. Such an observation suggested a stabilising effect in high ionic strength (IS) 100HM, such an effect was confirmed by lower dissolution in 100HM relative...

Evaluating Research Ethics Training in the Maryland Sea Grant REU Program

Science.gov (United States)

Allen, M. R.; Kumi, G. A.; Kumi, B. C.; Moser, F. C.

2016-02-01

The NSF's Research Experiences for Undergraduates (REU) program is an opportunity to cultivate responsible research practices in researchers at an early stage in their career. However, teaching responsible research conduct and science ethics in this program has been challenging because of a lack of consensus regarding which instructional methods are most effective for educating students about ethical concepts and establishing the process of ethical decision-making. Over the last 15 years, Maryland Sea Grant's REU ethics program has evolved by exploring different teaching models and looking for ways to effectively engage upper level undergraduates throughout their summer experience in ethical responsibility training. Since 2007, we have adopted a concerted experiential learning approach that includes an ethics seminar, role playing, case studies, and reflection. Currently, our summer long ethics training includes: 1) an interactive seminar; 2) a workshop with role playing and case studies; 3) 1-2 readings; and 4) a roundtable discussion with faculty mentors and their mentees to discuss researchers' real-world experiences with ethical dilemmas. Within the last 3 years, we have expanded our student learning outcomes assessments by administering pre- and post-program surveys to assess ethical skills students acquire through the program. Reevaluations administered three and six years after the REU experience will measure long term effectiveness of the training. Results from the first group of students reveal a greater awareness of ethical issues following our summer program. Students show a high level of competence about "black and white" issues (falsification, fabrication, plagiarism), but are more challenged by ethical "gray areas" such as data ownership and authorship. Results suggest many undergraduates come to research programs with basic ethics training, but benefit from our additional focus on complex ethical dilemmas.

34 CFR 461.1 - What is the Adult Education State-administered Basic Grant Program?

Science.gov (United States)

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false What is the Adult Education State-administered Basic...-ADMINISTERED BASIC GRANT PROGRAM General § 461.1 What is the Adult Education State-administered Basic Grant Program? The Adult Education State-administered basic Grant Program (the program) is a cooperative effort...

76 FR 62455 - Announcement of Updated Funding Availability for H-1B Technical Skills Training Grants

Science.gov (United States)

2011-10-07

... 10-13] Announcement of Updated Funding Availability for H-1B Technical Skills Training Grants AGENCY... the availability of $240 million for the H-1B Technical Skills Training Grants to be awarded through a... additional applicants to apply for the H-1B Technical Skills Training Grants competition that will close on...

Blinding Applicants in a First-Stage Peer-Review Process of Biomedical Research Grants: An Observational Study

Science.gov (United States)

Solans-Domènech, Maite; Guillamón, Imma; Ribera, Aida; Ferreira-González, Ignacio; Carrion, Carme; Permanyer-Miralda, Gaietà; Pons, Joan M. V.

2017-01-01

To blind or not researcher's identity has often been a topic of debate in the context of peer-review process for scientific publication and research grant application. This article reports on how knowing the name and experience of researchers/institutions influences the qualification of a proposal. We present our experience of managing the…

DOE/Industry Matching Grant Program

International Nuclear Information System (INIS)

Lee, John C.

2003-01-01

For the academic year 2001-2002, the Department of Nuclear Engineering and Radiological Sciences received $50,000 of industrial contributions, matched by a DOE grant of $35,000. We used the combined DOE/Industry Matching Grant of $85,000 toward (a) undergraduate merit scholarships and research support, (b) graduate student support, and (c) partial support of a research scientist

Host-agent-vector-environment measures for electronic cigarette research used in NIH grants.

Science.gov (United States)

Garcia-Cazarin, Mary L; Mandal, Rachel J; Grana, Rachel; Wanke, Kay L; Meissner, Helen I

2018-01-13

The purpose of this study is to describe the focus and comprehensiveness of domains measured in e-cigarette research. A portfolio analysis of National Institutes of Health grants focusing on e-cigarette research and funded between the fiscal years 2007 and 2015 was conducted. Grant proposals were retrieved using a government database and coded using the Host-Agent-Vector-Environment (HAVE) model as a framework to characterise the measures proposed. Eighty-one projects met the criteria for inclusion in the analysis. The primary HAVE focus most commonly found was Host (73%), followed by Agent (21%), Vector (6%) and Environment (0%). Intrapersonal measures and use trajectories were the most common measures in studies that include Host measures (n=59 and n=51, respectively). Product composition was the most common area of measurement in Agent studies (n=24), whereas Marketing (n=21) was the most common (n=21) area of Vector measurement. When Environment measures were examined as secondary measures in studies, they primarily focused on measuring Peer, Occupation and Social Networks (n=18). Although all studies mentioned research on e-cigarettes, most (n=52; 64%) did not specify the type of e-cigarette device or liquid solution under study. This analysis revealed a heavy focus on Host measures (73%) and a lack of focus on Environment measures. The predominant focus on Host measures may have the unintended effect of limiting the evidence base for tobacco control and regulatory science. Further, a lack of specificity about the e-cigarette product under study will make comparing results across studies and using the outcomes to inform tobacco policy difficult. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Technical Education Outreach in Materials Science and Technology Based on NASA's Materials Research

Science.gov (United States)

Jacobs, James A.

2003-01-01

The grant NAG-1 -2125, Technical Education Outreach in Materials Science and Technology, based on NASA s Materials Research, involves collaborative effort among the National Aeronautics and Space Administration s Langley Research Center (NASA-LaRC), Norfolk State University (NSU), national research centers, private industry, technical societies, colleges and universities. The collaboration aims to strengthen math, science and technology education by providing outreach related to materials science and technology (MST). The goal of the project is to transfer new developments from LaRC s Center for Excellence for Structures and Materials and other NASA materials research into technical education across the nation to provide educational outreach and strengthen technical education. To achieve this goal we are employing two main strategies: 1) development of the gateway website and 2) using the National Educators Workshop: Update in Engineering Materials, Science and Technology (NEW:Updates). We have also participated in a number of national projects, presented talks at technical meetings and published articles aimed at improving k-12 technical education. Through the three years of this project the NSU team developed the successful MST-Online site and continued to upgrade and update it as our limited resources permitted. Three annual NEW:Updates conducted from 2000 though 2002 overcame the challenges presented first by the September 11,2001 terrorist attacks and the slow U.S. economy and still managed to conduct very effective workshops and expand our outreach efforts. Plans began on NEW:Update 2003 to be hosted by NASA Langley as a part of the celebration of the Centennial of Controlled Flight.

Science Granting Councils Initiative: Research uptake | IDRC ...

International Development Research Centre (IDRC) Digital Library (Canada)

The Science Granting Councils Initiative in sub-Saharan Africa aims to ... The strategy identifies a wide range of activities to collect, package, and share lessons ... Organization for Women in Science for the Developing World (OWSD), IDRC is ...

Competitive Research Grants and Industry Collaboration: A Challenge for Universities in the 1990s.

Science.gov (United States)

Johnson, Peter

1993-01-01

The reasons for increased collaboration between Australian universities and industry are examined, focusing on competitive research grant programs developed by the government in the last decade. University and industry response to these opportunities and to issues such as intellectual property rights and publication rights are discussed. (MSE)

Edwin Grant Dexter: an early researcher in human behavioral biometeorology

Science.gov (United States)

Stewart, Alan E.

2015-06-01

Edwin Grant Dexter (1868-1938) was one of the first researchers to study empirically the effects of specific weather conditions on human behavior. Dexter (1904) published his findings in a book, Weather influences. The author's purposes in this article were to (1) describe briefly Dexter's professional life and examine the historical contexts and motivations that led Dexter to conduct some of the first empirical behavioral biometeorological studies of the time, (2) describe the methods Dexter used to examine weather-behavior relationships and briefly characterize the results that he reported in Weather influences, and (3) provide a historical analysis of Dexter's work and assess its significance for human behavioral biometeorology. Dexter's Weather influences, while demonstrating an exemplary approach to weather, health, and behavior relationships, came at the end of a long era of such studies, as health, social, and meteorological sciences were turning to different paradigms to advance their fields. For these reasons, Dexter's approach and contributions may not have been fully recognized at the time and are, consequently, worthy of consideration by contemporary biometeorologists.

Developing a methodology to assess the impact of research grant funding: a mixed methods approach.

Science.gov (United States)

Bloch, Carter; Sørensen, Mads P; Graversen, Ebbe K; Schneider, Jesper W; Schmidt, Evanthia Kalpazidou; Aagaard, Kaare; Mejlgaard, Niels

2014-04-01

This paper discusses the development of a mixed methods approach to analyse research funding. Research policy has taken on an increasingly prominent role in the broader political scene, where research is seen as a critical factor in maintaining and improving growth, welfare and international competitiveness. This has motivated growing emphasis on the impacts of science funding, and how funding can best be designed to promote socio-economic progress. Meeting these demands for impact assessment involves a number of complex issues that are difficult to fully address in a single study or in the design of a single methodology. However, they point to some general principles that can be explored in methodological design. We draw on a recent evaluation of the impacts of research grant funding, discussing both key issues in developing a methodology for the analysis and subsequent results. The case of research grant funding, involving a complex mix of direct and intermediate effects that contribute to the overall impact of funding on research performance, illustrates the value of a mixed methods approach to provide a more robust and complete analysis of policy impacts. Reflections on the strengths and weaknesses of the methodology are used to examine refinements for future work. Copyright © 2014 Elsevier Ltd. All rights reserved.

Satellite-Based Stratospheric and Tropospheric Measurements: Determination of Global Ozone and Other Trace Species

Science.gov (United States)

Chance, Kelly

2003-02-01

This grant is an extension to our previous NASA Grant NAG5-3461, providing incremental funding to continue GOME (Global Ozone Monitoring Experiment) and SCIAMACHY (SCanning Imaging Absorption SpectroMeter for Atmospheric CHartographY) studies. This report summarizes research done under these grants through December 31, 2002. The research performed during this reporting period includes development and maintenance of scientific software for the GOME retrieval algorithms, consultation on operational software development for GOME, consultation and development for SCIAMACHY near-real-time (NRT) and off-line (OL) data products, and participation in initial SCIAMACHY validation studies. The Global Ozone Monitoring Experiment was successfully launched on the ERS-2 satellite on April 20, 1995, and remains working in normal fashion. SCIAMACHY was launched March 1, 2002 on the ESA Envisat satellite. Three GOME-2 instruments are now scheduled to fly on the Metop series of operational meteorological satellites (Eumetsat). K. Chance is a member of the reconstituted GOME Scientific Advisory Group, which will guide the GOME-2 program as well as the continuing ERS-2 GOME program.

Plagiarism in Grant Proposals

Science.gov (United States)

Markin, Karen M.

2012-01-01

It is not news that software exists to check undergraduate papers for plagiarism. What is less well known is that some federal grant agencies are using technology to detect plagiarism in grant proposals. That variety of research misconduct is a growing problem, according to federal experts. The National Science Foundation, in its most recent…

The early history of research funding in South Africa: From the Research Grant Board to the FRD

Directory of Open Access Journals (Sweden)

Ndivhuwo M. Luruli

2016-05-01

Full Text Available The South African government has a long tradition of supporting research at public higher education institutions. Such support commenced in the early 20th century, although the exact nature of the support at that time is poorly documented. The oldest research funding model in the country was agency funding, which started as early as 1911 through the Royal Society of South Africa. A few years later, in 1918, a more coordinated funding body called the Research Grant Board (RGB was established in the Union of South Africa. The RGB offered competitive funding to individual academics in the natural and physical sciences. The human sciences were only supported much later with the establishment of the Council for Educational and Social Research in 1929. Here we review the history of research funding in South Africa, with a special focus on the work of the RGB between 1918 and 1938.

Multidimensional computer simulation of Stirling cycle engines

Science.gov (United States)

Hall, Charles A.; Porsching, Thomas A.

1992-01-01

This report summarizes the activities performed under NASA-Grant NAG3-1097 during 1991. During that period, work centered on the following tasks: (1) to investigate more effective solvers for ALGAE; (2) to modify the plotting package for ALGAE; and (3) to validate ALGAE by simulating oscillating flow problems similar to those studied by Kurzweg and Ibrahim.

Describing qualitative research undertaken with randomised controlled trials in grant proposals: a documentary analysis.

Science.gov (United States)

Drabble, Sarah J; O'Cathain, Alicia; Thomas, Kate J; Rudolph, Anne; Hewison, Jenny

2014-02-18

There is growing recognition of the value of conducting qualitative research with trials in health research. It is timely to reflect on how this qualitative research is presented in grant proposals to identify lessons for researchers and research commissioners. As part of a larger study focusing on how to maximise the value of undertaking qualitative research with trials, we undertook a documentary analysis of proposals of funded studies. Using the metaRegister of Controlled Trials (mRCT) database we identified trials funded in the United Kingdom, ongoing between 2001 and 2010, and reporting the use of qualitative research. We requested copies of proposals from lead researchers. We extracted data from the proposals using closed and open questions, analysed using descriptive statistics and content analysis respectively. 2% (89/3812) of trials in the mRCT database described the use of qualitative research undertaken with the trial. From these 89 trials, we received copies of 36 full proposals, of which 32 met our inclusion criteria. 25% used less than a single paragraph to describe the qualitative research. The aims of the qualitative research described in these proposals focused mainly on the intervention or trial conduct. Just over half (56%) of the proposals included an explicit rationale for conducting the qualitative research with the trial, the most frequent being to optimise implementation into clinical practice or to interpret trial findings. Key information about methods, expertise and resources was missing in a large minority of proposals, in particular sample size, type of analysis, and non-personnel resources. 28% specifically stated that qualitative researchers would conduct the qualitative research. Our review of proposals of successfully funded studies identified good practice but also identified limited space given to describing the qualitative research, with an associated lack of attention to the rationale for doing the qualitative research and

Fusion plasma theory grant: Task 1, Magnetic confinement fusion plasma theory

International Nuclear Information System (INIS)

Callen, J.D.

1989-07-01

The research performed under this grant during the current year has concentrated on key tokamak plasma confinement and heating theory issues: further development of neoclassical MHD; development of a new fluid/kinetic hybrid model; energy confinement degradation due to macroscopic phenomena in tokamaks; and some other topics (magnetics analysis, coherent structures, presheath structure). Progress and publications in these areas are briefly summarized in this report. 20 refs

Florida Tech professor gets three-year grant

CERN Multimedia

2003-01-01

"Dr. Marc Baarmand, Florida Tech associate professor of physics, has received a three-year grant from the U.S. Department of Energy's Division of High Energy Physics, to conduct research with the Compact Muon Solenoid experiment" (1/3 page).

Do AAO-HNSF CORE Grants Predict Future NIH Funding Success?

Science.gov (United States)

Eloy, Jean Anderson; Svider, Peter F; Kanumuri, Vivek V; Folbe, Adam J; Setzen, Michael; Baredes, Soly

2014-08-01

To determine (1) whether academic otolaryngologists who have received an American Academy of Otolaryngology- Head and Neck Surgery Foundation (AAO-HNSF) Centralized Otolaryngology Research Efforts (CORE) grant are more likely to procure future National Institutes of Health (NIH) funding; (2) whether CORE grants or NIH Career Development (K) awards have a stronger association with scholarly impact. Historical cohort. Scholarly impact, as measured by the h-index, publication experience, and prior grant history, were determined for CORE-funded and non-CORE-funded academic otolaryngologists. All individuals were assessed for NIH funding history. Of 192 academic otolaryngologists with a CORE funding history, 39.6% had active or prior NIH awards versus 15.1% of 1002 non-CORE-funded faculty (P productivity than those with CORE funding history. Both cohorts had higher scholarly impact values than previously published figures among academic otolaryngologists, highlighting that both CORE grants and NIH K-grants awards are effective career development resources. © American Academy of Otolaryngology—Head and Neck Surgery Foundation 2014.

Describing qualitative research undertaken with randomised controlled trials in grant proposals: a documentary analysis

Science.gov (United States)

2014-01-01

Background There is growing recognition of the value of conducting qualitative research with trials in health research. It is timely to reflect on how this qualitative research is presented in grant proposals to identify lessons for researchers and research commissioners. As part of a larger study focusing on how to maximise the value of undertaking qualitative research with trials, we undertook a documentary analysis of proposals of funded studies. Methods Using the metaRegister of Controlled Trials (mRCT) database we identified trials funded in the United Kingdom, ongoing between 2001 and 2010, and reporting the use of qualitative research. We requested copies of proposals from lead researchers. We extracted data from the proposals using closed and open questions, analysed using descriptive statistics and content analysis respectively. Results 2% (89/3812) of trials in the mRCT database described the use of qualitative research undertaken with the trial. From these 89 trials, we received copies of 36 full proposals, of which 32 met our inclusion criteria. 25% used less than a single paragraph to describe the qualitative research. The aims of the qualitative research described in these proposals focused mainly on the intervention or trial conduct. Just over half (56%) of the proposals included an explicit rationale for conducting the qualitative research with the trial, the most frequent being to optimise implementation into clinical practice or to interpret trial findings. Key information about methods, expertise and resources was missing in a large minority of proposals, in particular sample size, type of analysis, and non-personnel resources. 28% specifically stated that qualitative researchers would conduct the qualitative research. Conclusions Our review of proposals of successfully funded studies identified good practice but also identified limited space given to describing the qualitative research, with an associated lack of attention to the rationale for

77 FR 23229 - Submission for OMB Review; Small Business Innovation Research (SBIR) Program-Phase I-Grant...

Science.gov (United States)

2012-04-18

....133). This is in response to Public Law 106- 554, the ``Small Business Reauthorization Act of [[Page... DEPARTMENT OF EDUCATION Submission for OMB Review; Small Business Innovation Research (SBIR) Program--Phase I--Grant Application Package SUMMARY: This application package invites small business...

TJOG Vol 26 No 1.cdr

African Journals Online (AJOL)

Plasma C-Reactive Protein and Selected Nutritional Indices in Elective ... 13.27 respectively, while albumin reduced significantly (2.68 + 1.08) vs ... constitute the inflammatory response after ... acid mobilization from muscle used for hepatic.

78 FR 21262 - Grants to States for Construction or Acquisition of State Homes

Science.gov (United States)

2013-04-10

... Unit Renovation/Replacement.'' The note to Sec. 59.50(a)(1), which contains a chart to aid readers..., Dental health, Drug abuse, Foreign relations, Government contracts, Grant programs--health, Grant... and dental schools, Medical devices, Medical research, Mental health programs, Nursing homes...

Developing the Librarians' Role in Supporting Grant Applications and Reducing Waste in Research: Outcomes from a Literature Review and Survey in the NIHR Research Design Service

Science.gov (United States)

Edmunds Otter, Mary L.; Wright, Judy M.; King, Natalie V.

2017-01-01

Librarians and information specialists' involvement during the development of grant applications for external funding can save researchers' time, provide specialist support, and contribute to reducing avoidable waste in research. This article presents a survey of information specialists working for the National Institute for Health Research's…

Promoting Learning by Inquiry Among Undergraduates in Soil Sciences: Scaffolding From Project-based Courses to Student-Staff Research Grants by the National Research Agency in Oman

Science.gov (United States)

Al-Ismaily, Said; Kacimov, Anvar; Al-Maktoumi, Ali

2016-04-01

Three strategies in a soil science undergraduate programme with inquiry-based learning (IBL) principles at Sultan Qaboos University, Oman, are presented. The first strategy scaffolds courses into three phases: with direct instructional guidance, structured IBL, and finally, guided to open IBL. The second strategy involves extra-curricular activities of undergraduates, viz. conducting workshops on soils for pupils in grades 7-9 with their teachers. The third strategy promotes the teaching-research nexus through collaboration between the undergraduates and faculty within a student-supporting, government-funded programme through 1-year long research grants of up to 5,500 US/project. The efficiency of the strategies was evaluated by students' evaluations of courses and instructors and questionnaire-based surveys. Statistics of students' responses in teaching evaluations of IBL courses showed a significantly higher level of satisfaction compared with regular courses taught in the department and college. In surveys of other constituencies of the program, viz. the secondary schools, more than 90% of respondents "agreed" or "strongly agreed" that they had learned new information/secrets about soils. The indicators of success in the third strategy are: winning a highly competitive grant and, moreover, earning an even more competitive annual national award for the best executed research project. The two top graduates of the IBL soil programme progressed into the MSc programme with the university and national scholarships. Key words: inquiry based learning, soil science undergraduate program, scaffold of courses, outreach activities, teaching-research nexus, evaluation of program's efficiency

Effective collision frequency due to ion-acoustic instability: Theory and simulations

Czech Academy of Sciences Publication Activity Database

Hellinger, Petr; Trávníček, Pavel; Menietti, J. D.

2004-01-01

Roč. 31, č. 10 (2004), L10806 ISSN 0094-8276 R&D Projects: GA MŠk ME 500; GA AV ČR IAA3042403 Grant - others:ESA PRODEX(XE) 14529/00/NL/SFe; NASA (US) NAG5-11942 Institutional research plan: CEZ:AV0Z3042911 Keywords : Magnetospheric Physics: Plasma waves and instabilities * Space Plasma Physics: Kinetic and MHD theory * Space Plasma Physics: Magnetic reconnection Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 2.378, year: 2004

22 CFR 63.7 - Grants to United States participants to consult, lecture, teach, engage in research, demonstrate...

Science.gov (United States)

2010-04-01

... Section 63.7 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES PAYMENTS TO AND ON BEHALF OF PARTICIPANTS IN THE INTERNATIONAL EDUCATIONAL AND CULTURAL EXCHANGE PROGRAM § 63.7 Grants to... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Grants to United States participants to consult...

ATLAS PhD Grants 2015

CERN Multimedia

Marcelloni De Oliveira, Claudia

2015-01-01

ATLAS PHd Grants - We are excited to announce the creation of a dedicated grant scheme (thanks to a donation from Fabiola Gianotti and Peter Jenni following their award from the Fundamental Physics Prize foundation) to encourage young and high-caliber doctoral students in particle physics research (including computing for physics) and permit them to obtain world class exposure, supervision and training within the ATLAS collaboration. This special PhD Grant is aimed at graduate students preparing a doctoral thesis in particle physics (incl. computing for physics) to spend one year at CERN followed by one year support also at the home Institute.

Grant Closeout Requirements and Reports

Science.gov (United States)

Requirements and reports to comply with grant closeout, including Final Federal Financial Report (FFR, SF425); Final Research Performance Progress Report (FRPPR); Interim Research Performance Progress Report (IRPPR); Final Invention Statement (FIS, HHS

Environment assisted degradation mechanisms in aluminum-lithium alloys

Science.gov (United States)

Gangloff, Richard P.; Stoner, Glenn E.; Swanson, Robert E.

1988-01-01

Section 1 of this report records the progress achieved on NASA-LaRC Grant NAG-1-745 (Environment Assisted Degradation Mechanisms in Al-Li Alloys), and is based on research conducted during the period April 1 to November 30, 1987. A discussion of work proposed for the project's second year is included. Section 2 provides an overview of the need for research on the mechanisms of environmental-mechanical degradation of advanced aerospace alloys based on aluminum and lithium. This research is to provide NASA with the basis necessary to permit metallurgical optimization of alloy performance and engineering design with respect to damage tolerance, long term durability and reliability. Section 3 reports on damage localization mechanisms in aqueous chloride corrosion fatigue of aluminum-lithium alloys. Section 4 reports on progress made on measurements and mechanisms of localized aqueous corrosion in aluminum-lithium alloys. Section 5 provides a detailed technical proposal for research on environmental degradation of Al-Li alloys, and the effect of hydrogen in this.

Plasma Colloquium Travel Grant Program

International Nuclear Information System (INIS)

Hazeltine, R.D.

1998-01-01

OAK B188 Plasma Colloquium Travel Grant Program. The purpose of the Travel Grant Program is to increase the awareness of plasma research. The new results and techniques of plasma research in fusion plasmas, plasma processing space plasmas, basic plasma science, etc, have broad applicability throughout science. The benefits of these results are limited by the relatively low awareness and appreciation of plasma research in the larger scientific community. Whereas spontaneous interactions between plasma scientists and other scientists are useful, a focused effort in education and outreach to other scientists is efficient and is needed. The academic scientific community is the initial focus of this effort, since that permits access to a broad cross-section of scientists and future scientists including undergraduates, graduate students, faculty, and research staff

Nonlinear Acoustics: Periodic Waveguide, Scattering of Sound by Sound, Three-Layer Fluid, Finite Amplitude Sound in a Medium Having a Distribution of Relaxation Processes, and Production of an Isolated Negative Pulse in Water

Science.gov (United States)

1993-06-03

propagation and shape of the waveform," Conference on Lithotripsy (Extra-Corporeal Shock Wave Applications - Technical and Clinical Problems), Univer- sity of...Blackstock, "Physical aspects of lithotripsy ," Paper GG1, 115th Meeting, Acoustical Society of America, Seattle, 16-20 May 1988. ABSTRACT: J. Acoust...Am. 90, 2244(A) (1991). kAlso supported in part by Grant NAG-1-1204 and University of Southampton , Eng- land. 49 1992 ONR Contract Code 1109 JS 1. F

75 FR 53701 - Clinical Studies of Safety and Effectiveness of Orphan Products Research Project Grant (R01...

Science.gov (United States)

2010-09-01

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0394] Clinical Studies of Safety and Effectiveness of Orphan Products Research Project Grant (R01); Correction AGENCY: Food and Drug Administration, HHS. ACTION: Notice; correction. SUMMARY: The Food and Drug...

Integrity management, hydrocarbons transport: NAG 100-RES 1460

Energy Technology Data Exchange (ETDEWEB)

Teutonico, Jose Mauricio; Soula, Gerardo [GIE S.A., Lima (Peru)

2009-12-19

In May, 2007, a series of tasks were implemented in the actives of the client at Patagonia, Argentina, with the purpose of applying a Pipeline Integrity System. The purpose of this system is to effectively operate their facilities in such a way that no adverse effects are suffered by their employees, the environment, or the public at large, which is one of the main goals followed by any oil pipeline operator. In this paper, all tasks, inspections, controls and records made by the operator about gas and liquid hydrocarbons Pipelines contemplated by local requirements, NAG 100 and Resolution 1460 are described. Firstly, a description of gas and liquid hydrocarbons transport systems was made. This description consisted in the recollection of basic information about construction, maintenance, operation and inspection. Later, tasks to complete the ILI process started by the company in the past were implemented. This implementation consisted in the analysis of inspections that were made, priority of anomalies to verify, definition of verifications, direct assessment and analysis of the results. A gap analysis was made with the purpose of stating the compliance level of the normative requirements for each system. This analysis consisted in the determination of the company's practices about applicable regulations. As a result of this, a series of duties were developed from the collection and integration of information, using the database that was already implemented by the company. A risk analysis was also made, based on the determination of the kind of events or adverse conditions that can make an impact in the oil pipeline, the possibilities that these events or condition can conduct to a failure, and the seriousness of the possible consequences that these failures can produce. With the results of the risk analysis, the Inspection plan developed by the company was refreshed and it resulted in an improvement Plan in data collection and identification of sensitive

Cyclooxygenase inhibitors induce apoptosis in oral cavity cancer cells by increased expression of nonsteroidal anti-inflammatory drug-activated gene

International Nuclear Information System (INIS)

Kim, Kyung-Su; Yoon, Joo-Heon; Kim, Jin Kook; Baek, Seung Joon; Eling, Thomas E.; Lee, Won Jae; Ryu, Ji-Hwan; Lee, Jeung Gweon; Lee, Joo-Hwan; Yoo, Jong-Bum

2004-01-01

We have investigated whether NAG-1 is induced in oral cavity cancer cells by various NSAIDs and if apoptosis induced by NSAIDs can be linked directly with the induction of NAG-1. NAG-1 expression was increased by diclofenac, aceclofenac, indomethacin, ibuprofen, and sulindac sulfide, in the order of NAG-1 induction, but not by acetaminophen, piroxicam or NS-398. Diclofenac was the most effective NAG-1 inducer. Incubation with diclofenac inhibited cell proliferation and induced apoptosis. The expression of NAG-1 was observed in advance of the induction of apoptosis. Conditioned medium from NAG-1-overexpressing Drosophila cells inhibited SCC 1483 cells proliferation and induced apoptosis. In summary, some NSAIDs induce NAG-1 expression in oral cavity cancer cells and the induced NAG-1 protein appears to mediate apoptosis. Therefore, NSAIDs may be considered as a possible chemopreventive agent against oral cavity cancer

Sea Grant in California: Twenty Years of Achievement.

Science.gov (United States)

Amidei, Rosemary

Since 1968, the California Sea Grant program has operated to produce scientific research oriented to solving problems in marine resource development, management, and conservation. This document decribes the facets of this program, their accomplishments and goals. Discussions include: (1) historical notes; (2) coastal governance; (3) coastal…

University Reactor Matching Grants Program

International Nuclear Information System (INIS)

John Valentine; Farzad Rahnema; Said Abdel-Khalik

2003-01-01

During the 2002 Fiscal year, funds from the DOE matching grant program, along with matching funds from the industrial sponsors, have been used to support research in the area of thermal-hydraulics. Both experimental and numerical research projects have been performed. Experimental research focused on two areas: (1) Identification of the root cause mechanism for axial offset anomaly in pressurized water reactors under prototypical reactor conditions, and (2) Fluid dynamic aspects of thin liquid film protection schemes for inertial fusion reactor chambers. Numerical research focused on two areas: (1) Multi-fluid modeling of both two-phase and two-component flows for steam conditioning and mist cooling applications, and (2) Modeling of bounded Rayleigh-Taylor instability with interfacial mass transfer and fluid injection through a porous wall simulating the ''wetted wall'' protection scheme in inertial fusion reactor chambers. Details of activities in these areas are given

The current state of funded NIH grants in implementation science in genomic medicine: a portfolio analysis.

Science.gov (United States)

Roberts, Megan C; Clyne, Mindy; Kennedy, Amy E; Chambers, David A; Khoury, Muin J

2017-10-26

PurposeImplementation science offers methods to evaluate the translation of genomic medicine research into practice. The extent to which the National Institutes of Health (NIH) human genomics grant portfolio includes implementation science is unknown. This brief report's objective is to describe recently funded implementation science studies in genomic medicine in the NIH grant portfolio, and identify remaining gaps.MethodsWe identified investigator-initiated NIH research grants on implementation science in genomic medicine (funding initiated 2012-2016). A codebook was adapted from the literature, three authors coded grants, and descriptive statistics were calculated for each code.ResultsForty-two grants fit the inclusion criteria (~1.75% of investigator-initiated genomics grants). The majority of included grants proposed qualitative and/or quantitative methods with cross-sectional study designs, and described clinical settings and primarily white, non-Hispanic study populations. Most grants were in oncology and examined genetic testing for risk assessment. Finally, grants lacked the use of implementation science frameworks, and most examined uptake of genomic medicine and/or assessed patient-centeredness.ConclusionWe identified large gaps in implementation science studies in genomic medicine in the funded NIH portfolio over the past 5 years. To move the genomics field forward, investigator-initiated research grants should employ rigorous implementation science methods within diverse settings and populations.Genetics in Medicine advance online publication, 26 October 2017; doi:10.1038/gim.2017.180.

Using Matching Grants to Facilitate Corporate-University Research Linkages: A Preliminary Examination of Outcomes from One Initiative.

Science.gov (United States)

Bell, Stephen

1990-01-01

A study used public finance theory to evaluate Ontario's matching grants in support of university-industry interaction, which encourage faculty to seek new research and development contracts facilitating technology transfer activities. Results suggest it may not be an effective mechanism. Conceptual and methodological obstacles to assessing these…

Nanotechnology applications and implications research supported by the US Environmental Protection Agency STAR grants program.

Science.gov (United States)

Savage, Nora; Thomas, Treye A; Duncan, Jeremiah S

2007-10-01

Since 2002, the US Environmental Protection Agency (EPA) has been funding research on the environmental aspects of nanotechnology through its Science to Achieve Results (STAR) grants program. In total, more than $25 million has been awarded for 86 research projects on the environmental applications and implications of nanotechnology. In the applications area, grantees have produced promising results in green manufacturing, remediation, sensors, and treatment using nanotechnology and nanomaterials. Although there are many potential benefits of nanotechnology, there has also been increasing concern about the environmental and health effects of nanomaterials, and there are significant gaps in the data needed to address these concerns. Research performed by STAR grantees is beginning to address these needs.

Inhibitory Effects of Salinomycin on Cell Survival, Colony Growth, Migration, and Invasion of Human Non-Small Cell Lung Cancer A549 and LNM35: Involvement of NAG-1.

Directory of Open Access Journals (Sweden)

Kholoud Arafat

Full Text Available A major challenge for oncologists and pharmacologists is to develop more potent and less toxic drugs that will decrease the tumor growth and improve the survival of lung cancer patients. Salinomycin is a polyether antibiotic used to kill gram-positive bacteria including mycobacteria, protozoans such as plasmodium falciparum, and the parasites responsible for the poultry disease coccidiosis. This old agent is now a serious anti-cancer drug candidate that selectively inhibits the growth of cancer stem cells. We investigated the impact of salinomycin on survival, colony growth, migration and invasion of the differentiated human non-small cell lung cancer lines LNM35 and A549. Salinomycin caused concentration- and time-dependent reduction in viability of LNM35 and A549 cells through a caspase 3/7-associated cell death pathway. Similarly, salinomycin (2.5-5 µM for 7 days significantly decreased the growth of LNM35 and A549 colonies in soft agar. Metastasis is the main cause of death related to lung cancer. In this context, salinomycin induced a time- and concentration-dependent inhibition of cell migration and invasion. We also demonstrated for the first time that salinomycin induced a marked increase in the expression of the pro-apoptotic protein NAG-1 leading to the inhibition of lung cancer cell invasion but not cell survival. These findings identify salinomycin as a promising novel therapeutic agent for lung cancer.

District-Charter Collaboration Grant Implementation: Findings from Interviews and Site Visits

OpenAIRE

Moira McCullough; Luke Heinkel; Betsy Keating

2015-01-01

This document is an interim report examining the implementation of district-charter collaboration grants funded by the Bill & Melinda Gates Foundation. The report addresses three key research questions: (1) To what extent do schools and staff collaborate across sectors and how have grant activities influenced collaboration among participating staff through the first 12 to 15 months of implementation? (2) What contextual factors currently play a role in implementation of the collaboration gran...

Navigating the Road to Success: A Systematic Approach to Preparing Competitive Grant Proposals

Directory of Open Access Journals (Sweden)

Theresa Mackenzie

2007-03-01

Full Text Available Purpose Difficulty in securing research funding has been cited as one barrier to the involvement of more librarians and information professionals in conducting original research. This article seeks to support the work of librarians who wish to secure research funding by describing a systematic approach to the creation of successful grant applications.Approach The authors draw on more than fifteen years collective experience in supporting the development of successful research grant proposals. Eleven grant‐writing best practicesor ‘key approaches’ are described, and a planning timeline is suggested.Conclusions: Use of these best practices can assist researchers in creating successful research grant proposals that will also help streamline the research process once it is underway. It is important to recognize the competitive nature of research grant competitions, obtain feedback from an internal review panel, and use feedback from funding agencies to strengthen future grant applications.

Bud development types as a new macroscopic marker of Norwayspruce decline and recovery processes along a mountainous pollution gradient

Czech Academy of Sciences Publication Activity Database

Polák, T.; Albrechtová, Jana; Rock, B. N.

2006-01-01

Roč. 79, č. 4 (2006), s. 425-437 ISSN 0015-752X R&D Projects: GA ČR(CZ) GD206/03/H137; GA MŠk(CZ) ME 658 Grant - others:GA AV ČR(CZ) KJB6111307; NASA (US) NAG5-5192; NSF(US) NSF108385 Institutional research plan: CEZ:AV0Z60050516 Source of funding: R - rámcový projekt EK ; V - iné verejné zdroje Keywords : forest ecophysiology * Norway spruce * bud macroscopic marker Subject RIV: EF - Botanics Impact factor: 0.847, year: 2006

Undergraduate research involving human subjects should not be granted ethical approval unless it is likely to be of publishable quality.

Science.gov (United States)

Gallagher, Cathal T; McDonald, Lisa J; McCormack, Niamh P

2014-06-01

Small-scale research projects involving human subjects have been identified as being effective in developing critical appraisal skills in undergraduate students. In deciding whether to grant ethical approval to such projects, university research ethics committees must weigh the benefits of the research against the risk of harm or discomfort to the participants. As the learning objectives associated with student research can be met without the need for human subjects, the benefit associated with training new healthcare professionals cannot, in itself, justify such risks. The outputs of research must be shared with the wider scientific community if it is to influence future practice. Our survey of 19 UK universities indicates that undergraduate dissertations associated with the disciplines of medicine, dentistry and pharmacy are not routinely retained in their library catalogues, thus closing a major avenue to the dissemination of their findings. If such research is unlikely to be published in a peer-reviewed journal, presented at a conference, or otherwise made available to other researchers, then the risks of harm, discomfort or inconvenience to participants are unlikely to be offset by societal benefits. Ethics committees should be satisfied that undergraduate research will be funnelled into further research that is likely to inform clinical practice before granting ethical approval.

Dopravně závislé řízení silničního provozu ve městech (1. část)

Czech Academy of Sciences Publication Activity Database

Nagy, Ivan; Homolová, Jitka; Pecherková, Pavla

2007-01-01

Roč. 13, č. 6 (2007), s. 12-16 ISSN 1210-9592 R&D Projects: GA MDS 1F43A/003/120 Institutional research plan: CEZ:AV0Z10750506 Keywords : Traffic control * linear system * Kalman filtering * linear optimization Subject RIV: BC - Control Systems Theory http://as.utia.cz/publications/2007/NagHomPec_07.pdf

Outline of research program on thorium fuel supported by grant-in-aid for energy research of ministry of education, science and culture

International Nuclear Information System (INIS)

Shibata, Toshikazu

1984-01-01

Since 1980, the Research Program on Thorium Fuel has been performed under the support of Grant-in-Aid for Energy Research of the Ministry of Education, Science and Culture of Japanese Government on the university basis including several tens professors. The main results have been published in the English-written report, ''Research on Thorium Fuel (SPEY-9, 1984)''. This report describes the outline and review of the symposium held on January 31, 1984. It consists of nuclear data, reactor physics, thorium fuel, irradiation of thorium, down-stream, biological effect, molten salt reactor engineering and others. It has been the first trial to perform such a big systematic cooperative studies in nuclear field on the university basis in Japan. (author)

Grants Solutions -

Data.gov (United States)

Department of Transportation — The Grants Center of Excellence The Grants Center of Excellence (COE) delivers end-to-end grants management products and support to over 17 Federal partner agencies....

Nonlinear Acoustics: Periodic Waveguide, Finite-Amplitude Propagation in a Medium Having a Distribution of Relaxation Processes, and Production of an Isolated Negative Pulse in Water

Science.gov (United States)

1993-08-24

T. Blackstock, "Shock wave propagation and shape of the waveform," Conference on Lithotripsy (Extra-Corporeal Shock Wave Applications - Technical and...83, S5 (1988). 0574 0 b4 . D. T. Blackstock, "Physical aspects of lithotripsy ," Paper GG1, 115th Meeting, Acoustical Society of America, Seattle, 16...1991). kAlso supported in part by Grant NAG-1-1204 and University of Southampton , Eng- land. 23 1992 ONR Contract Code 1109 0 𔃻. James A. Ten Cate

Peer Review Practices for Evaluating Biomedical Research Grants: A Scientific Statement From the American Heart Association.

Science.gov (United States)

Liaw, Lucy; Freedman, Jane E; Becker, Lance B; Mehta, Nehal N; Liscum, Laura

2017-08-04

The biomedical research enterprise depends on the fair and objective peer review of research grants, leading to the distribution of resources through efficient and robust competitive methods. In the United States, federal funding agencies and foundations collectively distribute billions of dollars annually to support biomedical research. For the American Heart Association, a Peer Review Subcommittee is charged with establishing the highest standards for peer review. This scientific statement reviews the current literature on peer review practices, describes the current American Heart Association peer review process and those of other agencies, analyzes the strengths and weaknesses of American Heart Association peer review practices, and recommends best practices for the future. © 2017 American Heart Association, Inc.

Current fusion plasma theory grant: Task I, Magnetic confinement fusion plasma theory: Final report, December 1, 1987--November 14, 1988

International Nuclear Information System (INIS)

Callen, J.D.

1988-07-01

The research performed under this grant over the current 11-1/2 month period has concentrated on key tokamak plasma confinement and heating theory issues: extensions of neoclassical MHD; viscosity coefficients and transport; nonlinear resistive MHD simulations of Tokapole II plasmas; ICRF and edge plasma interactions; energy confinement degradation due to macroscopic phenomena; and coordination of a new transport initiative. Progress and publications in these areas are briefly summarized in this report. 21 refs

Networking Africa's science granting councils | IDRC - International ...

International Development Research Centre (IDRC) Digital Library (Canada)

Networking Africa's science granting councils ... to support research and evidence-based policies that contribute to social and economic development. ... exchanges and forums, online training, on-site coaching, and collaborative research.

Science Granting Councils Initiative in Sub-Saharan Africa ...

International Development Research Centre (IDRC) Digital Library (Canada)

This initiative seeks to strengthen the capacities of science granting councils in East Africa and other selected sub-Saharan African countries. The goal is to contribute to economic and social development in the region through research and evidence-based policies. About the science granting councils initiative The Science ...

University of California Sea Grant College Program, Annual Report 1974-1975. September 1, 1974 to August 31, 1975.

Science.gov (United States)

Powell, Robert, Ed.

Presented is a general overview and summary of the 1974-1975 Sea Grant Program activities and research. Included are marine advisory services, education, coastal resources, aquaculture, fisheries, new marine products, and energy resources. (SL)

Office of Grants Administration (OGA)

Science.gov (United States)

OGA manages all NCI business-related activities associated with the negotiation, award, and administration of NCI grants and cooperative agreements to help financially support cancer research activities throughout the United States and around the world.

How well does early-career investigators' cardiovascular outcomes research training align with funded outcomes research?

Science.gov (United States)

Crowley, Matthew J; Al-Khatib, Sana M; Wang, Tracy Y; Khazanie, Prateeti; Kressin, Nancy R; Krumholz, Harlan M; Kiefe, Catarina I; Wells, Barbara L; O'Brien, Sean M; Peterson, Eric D; Sanders, Gillian D

2018-02-01

Outcomes research training programs should prepare trainees to successfully compete for research funding. We examined how early-career investigators' prior and desired training aligns with recently funded cardiovascular (CV) outcomes research. We (1) reviewed literature to identify 13 core competency areas in CV outcomes research; (2) surveyed early-career investigators to understand their prior and desired training in each competency area; (3) examined recently funded grants commonly pursued by early-career outcomes researchers to ascertain available funding in competency areas; and (4) analyzed alignment between investigator training and funded research in each competency area. We evaluated 185 survey responses from early-career investigators (response rate 28%) and 521 funded grants from 2010 to 2014. Respondents' prior training aligned with funded grants in the areas of clinical epidemiology, observational research, randomized controlled trials, and implementation/dissemination research. Funding in community-engaged research and health informatics was more common than prior training in these areas. Respondents' prior training in biostatistics and systematic review was more common than funded grants focusing on these specific areas. Respondents' desired training aligned similarly with funded grants, with some exceptions; for example, desired training in health economics/cost-effectiveness research was more common than funded grants in these areas. Restricting to CV grants (n=132) and National Heart, Lung, and Blood Institute-funded grants (n=170) produced similar results. Identifying mismatch between funded grants in outcomes research and early-career investigators' prior/desired training may help efforts to harmonize investigator interests, training, and funding. Our findings suggest a need for further consideration of how to best prepare early-career investigators for funding success. Copyright © 2017. Published by Elsevier Inc.

Natural type 3/type 2 intertypic vaccine-related poliovirus recombinants with the first crossover sites within the VP1 capsid coding region.

Science.gov (United States)

Zhang, Yong; Zhu, Shuangli; Yan, Dongmei; Liu, Guiyan; Bai, Ruyin; Wang, Dongyan; Chen, Li; Zhu, Hui; An, Hongqiu; Kew, Olen; Xu, Wenbo

2010-12-21

Ten uncommon natural type 3/type 2 intertypic poliovirus recombinants were isolated from stool specimens from nine acute flaccid paralysis case patients and one healthy vaccinee in China from 2001 to 2008. Complete genomic sequences revealed their vaccine-related genomic features and showed that their first crossover sites were randomly distributed in the 3' end of the VP1 coding region. The length of donor Sabin 2 sequences ranged from 55 to 136 nucleotides, which is the longest donor sequence reported in the literature for this type of poliovirus recombination. The recombination resulted in the introduction of Sabin 2 neutralizing antigenic site 3a (NAg3a) into a Sabin 3 genomic background in the VP1 coding region, which may have been altered by some of the type 3-specific antigenic properties, but had not acquired any type 2-specific characterizations. NAg3a of the Sabin 3 strain seems atypical; other wild-type poliovirus isolates that have circulated in recent years have sequences of NAg3a more like the Sabin 2 strain. 10 natural type 3/type 2 intertypic VP1 capsid-recombinant polioviruses, in which the first crossover sites were found to be in the VP1 coding region, were isolated and characterized. In spite of the complete replacement of NAg3a by type 2-specific amino acids, the serotypes of the recombinants were not altered, and they were totally neutralized by polyclonal type 3 antisera but not at all by type 2 antisera. It is possible that recent type 3 wild poliovirus isolates may be a recombinant having NAg3a sequences derived from another strain during between 1967 and 1980, and the type 3/type 2 recombination events in the 3' end of the VP1 coding region may result in a higher fitness.

Natural type 3/type 2 intertypic vaccine-related poliovirus recombinants with the first crossover sites within the VP1 capsid coding region.

Directory of Open Access Journals (Sweden)

Yong Zhang

Full Text Available BACKGROUND: Ten uncommon natural type 3/type 2 intertypic poliovirus recombinants were isolated from stool specimens from nine acute flaccid paralysis case patients and one healthy vaccinee in China from 2001 to 2008. PRINCIPAL FINDINGS: Complete genomic sequences revealed their vaccine-related genomic features and showed that their first crossover sites were randomly distributed in the 3' end of the VP1 coding region. The length of donor Sabin 2 sequences ranged from 55 to 136 nucleotides, which is the longest donor sequence reported in the literature for this type of poliovirus recombination. The recombination resulted in the introduction of Sabin 2 neutralizing antigenic site 3a (NAg3a into a Sabin 3 genomic background in the VP1 coding region, which may have been altered by some of the type 3-specific antigenic properties, but had not acquired any type 2-specific characterizations. NAg3a of the Sabin 3 strain seems atypical; other wild-type poliovirus isolates that have circulated in recent years have sequences of NAg3a more like the Sabin 2 strain. CONCLUSIONS: 10 natural type 3/type 2 intertypic VP1 capsid-recombinant polioviruses, in which the first crossover sites were found to be in the VP1 coding region, were isolated and characterized. In spite of the complete replacement of NAg3a by type 2-specific amino acids, the serotypes of the recombinants were not altered, and they were totally neutralized by polyclonal type 3 antisera but not at all by type 2 antisera. It is possible that recent type 3 wild poliovirus isolates may be a recombinant having NAg3a sequences derived from another strain during between 1967 and 1980, and the type 3/type 2 recombination events in the 3' end of the VP1 coding region may result in a higher fitness.

Federal health services grants, 1985.

Science.gov (United States)

Zwick, D I

1986-01-01

Federal health services grants amounted to about $1.8 billion in fiscal year 1985. The total amount was about $100 million less, about 6 percent, than in 1980. Reductions in the health planning program accounted for most of the decline in absolute dollars. The four formula grants to State agencies amounted to about $1.0 billion in 1985, about 60 percent of the total. The largest formula grants were for maternal and child health services and for alcohol, drug abuse, and mental health services. Project grants to selected State and local agencies amounted to about $.8 billion. There was 12 such grants in 1985 (compared with 34 in 1980). The largest, for community health services, equaled almost half the total. In real, inflation-adjusted dollars, the decline in Federal funds for these programs exceeded a third during the 5-year period. The overall dollar total in real terms in 1985 approximated the 1970 level. The ratio of formula grants to project grants in 1985 was similar to that in 1965. Studies of the impact of changes in Federal grants have found that while the development of health programs has been seriously constrained in most cases, their nature has not been substantially altered. In some cases broader program approaches and allocations have been favored. Established modes of operations and administration have generally been strengthened. Some efficiencies but few savings in administration have been identified. Replacement of reduced Federal funding by the States has been modest but has increased over time, especially for direct service activities. These changes reflect the important influence of professionalism in the health fields and the varying strengths of political interest and influence among program supporters. The long-term impact on program innovation is not yet clear.

Non-equilibrium chemistry of the early solar system

Science.gov (United States)

Prinn, Ronald G.

1994-01-01

This final report contains a list of publications supported in whole or part by NAG9-108 in the time period 1 May 1985 to 30 April 1994. Also contained is a list of invited papers with abstracts supported in whole or part by this grant in the same time period. A copy of the 1993 paper by Ronald G. Prinn, 'Protostars and Planets III', is attached since it had not previously been sent to NASA.

25 CFR 23.21 - Noncompetitive tribal government grants.

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Noncompetitive tribal government grants. 23.21 Section 23... ACT Grants to Indian Tribes for Title II Indian Child and Family Service Programs § 23.21 Noncompetitive tribal government grants. (a) Grant application information and technical assistance. Information...

Documentation for Grants Equal to Tax model: Volume 1, Technical description

International Nuclear Information System (INIS)

1986-01-01

A computerized model, the Grants Equal to Tax (GETT) model, was developed to assist in evaluating the amount of federal grant monies that would go to state and local jurisdictions under the provisions outlined in the Nuclear Waste Policy Act of 1982. The GETT model is capable of forecasting the amount of tax liability associated with all property owned and all activities undertaken by the US Department of Energy (DOE) in site characterization and repository development. The GETT program is a user-friendly, menu-driven model developed using dBASE III/trademark/, a relational data base management system. The data base for GETT consists primarily of eight separate dBASE III/trademark/ files corresponding to each of the eight taxes levied by state and local jurisdictions on business property and activity. Additional smaller files help to control model inputs and reporting options. Volume 1 of the GETT model documentation is a technical description of the program and its capabilities providing (1) descriptions of the data management system and its procedures; (2) formulas for calculating taxes (illustrated with flow charts); (3) descriptions of tax data base variables for the Deaf Smith County, Texas, Richton Dome, Mississippi, and Davis Canyon, Utah, salt sites; and (4) data inputs for the GETT model. 10 refs., 18 figs., 3 tabs

Isothermal Titration Calorimetry and Macromolecular Visualization for the Interaction of Lysozyme and Its Inhibitors

Science.gov (United States)

Wei, Chin-Chuan; Jensen, Drake; Boyle, Tiffany; O'Brien, Leah C.; De Meo, Cristina; Shabestary, Nahid; Eder, Douglas J.

2015-01-01

To provide a research-like experience to upper-division undergraduate students in a biochemistry teaching laboratory, isothermal titration calorimetry (ITC) is employed to determine the binding constants of lysozyme and its inhibitors, N-acetyl glucosamine trimer (NAG[subscript 3]) and monomer (NAG). The extremely weak binding of lysozyme/NAG is…

NLM Informationist Grant – Web Assisted Tobacco Intervention for Community College Students

Directory of Open Access Journals (Sweden)

Linda Hasman

2013-05-01

Full Text Available In 2012 the National Library of Medicine awarded several academic medical libraries informationist grants to become embedded with a research team for the purposes of data management. The University of Rochester Medical Center was among those recipients. This article will give background on the research project and team that won the grant, discuss the process of applying for the grant, identify the data management role that the informationist librarians have agreed to work on, how they embedded into the research team, and relay lessons learned thus far in the project.

NIH and NCI grant-related changes during fiscal years 2014 and 2015

Science.gov (United States)

Wong, Rosemary S. L.

2015-03-01

The 2014 fiscal year (FY) continued to be a challenging one for all federal agencies despite the many Congressional strategies proposed to address the U.S. budget deficit. The Bipartisan Budget Act of 2013 passed by the House and Senate in December 2013 approved a two-year spending bill which cancelled the FY2014 and FY2015 required sequestration cuts (i.e., 4-5% National Institute of Health (NIH)/National Cancer Institute (NCI) budget reduction initiated on March 1, 2013), but extended the sequestration period through FY2023. This bill passage helped minimize any further budget reductions and resulted in a final FY2014 NIH budget of 29.9 billion and a NCI budget of 4.9 billion. Both NIH and NCI worked hard to maintain awarding the same number of NIH/NCI investigator-initiated R01 and exploratory R21 grants funded in FY2014 and similar to the level seen in FY2013 and previous years (see Tables 1 and 2). Since Congress only recently passed the 2015 spending bill in December 16, 2014, the final NIH and NCI budget appropriations for FY2015 remains unknown at this time and most likely will be similar to the FY2014 budget level. The NCI overall success and funding rates for unsolicited investigator-initiated R01 applications remained at 15%, while the success rate for exploratory R21 applications was 12% in FY2014 with similar rates seen in FY2013 (see Tables 1 and 2). The success rate for biomedical research applications in the Photodynamic Therapy and laser research field will be provided for the past few years. NIH provides numerous resources to help inform the extramural biomedical research community of new and current grant applicants about new grant policy changes and the grant submission and review processes.

25 CFR 23.51 - Grant carry-over authority.

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Grant carry-over authority. 23.51 Section 23.51 Indians... Uniform Grant Administration Provisions and Requirements § 23.51 Grant carry-over authority. Unless... two years beyond the initial grant funding period and must be utilized only for the intent, purpose...

Uncertain CERN cash means UK physicists face grant freeze.

CERN Document Server

1996-01-01

Britain's funding agency Particle Physics and Astronomy Research Council is uncertain about its ability to cover membership costs to the European Laboratory for Particle Physics (CERN). This has resulted in suspension of research grants to university physicists and astronomers. Funding will be available only for genuine hardship, and for major national and international astronomical projects that have already been sanctioned. The new four-year rolling grants to university-based particle physics group is withheld.

Medicinal Cannabis in California: An Interview with Igor Grant, MD.

Science.gov (United States)

Piomelli, Daniele; Grant, Igor

2016-01-01

Dr. Igor Grant, MD, is distinguished professor and chair of psychiatry and director of the HIV Neurobehavioral Research Program and the Center for Medicinal Cannabis Research at the University of California, San Diego. Dr. Grant is a neuropsychiatrist who graduated from the University of British Columbia School of Medicine (1966), and received specialty training in psychiatry at the University of Pennsylvania (1967-1971), and additional training in neurology at the Institute of Neurology (1980-1981), London, U.K. Dr. Grant's academic interests focus on the effects of various diseases on brain and behavior, with an emphasis on translational studies in HIV, and drugs of abuse. He has contributed to ∼700 scholarly publications and is principal investigator of several NIH studies, including an NIDA P50 (Translational Methamphetamine AIDS Research Center-TMARC), and is codirector of the HIV Neurobehavioral Research Center (HNRC).

42 CFR 52h.8 - What are the review criteria for grants?

Science.gov (United States)

2010-10-01

... research, from a scientific or technical standpoint; (b) The adequacy of the approach and methodology... SCIENTIFIC PEER REVIEW OF RESEARCH GRANT APPLICATIONS AND RESEARCH AND DEVELOPMENT CONTRACT PROJECTS § 52h.8 What are the review criteria for grants? In carrying out its review under § 52h.7, the scientific peer...

34 CFR 648.2 - Who is eligible for a grant?

Science.gov (United States)

2010-07-01

... support of doctoral dissertation research with one or more degree-granting institutions. (b) A formal... grant under this part for study at a school or department of divinity. (Authority: 20 U.S.C. 1135, 1135a) ...

You Can Get Grants!

Science.gov (United States)

Novelli, Joan

1994-01-01

Presents strategies to help elementary teachers win grants for the classroom. The article includes information on grant sources, where to find out more about grants, and how to write winning grants. Examples of successful grant projects are provided, and announcement of a $500 Instructor grant competition is included. (SM)

How Does Institutional Grant Aid Impact College Choice? Research Brief

Science.gov (United States)

Hurwitz, Michael

2012-01-01

New evidence on how students' choice of postsecondary institution is sensitive to grant aid offers from the colleges and universities. Institutional aid sensitivity is largest for students from the least wealthy families but does not vary by race/ethnicity or measured academic ability. A technical appendix is included.

NASA-UVA Light Aerospace Alloy and Structures Technology Program: LA(2)ST

Science.gov (United States)

Gangloff, Richard P.; Haviland, John K.; Herakovich, Carl T.; Pilkey, Walter D.; Pindera, Marek-Jerzy; Scully, John R.; Stoner, Glenn E.; Thornton, Earl A.; Wawner, Franklin E., Jr.; Wert, John A.

1993-01-01

The NASA-UVA Light Aerospace Alloy and Structures Technology (LA(2)ST) Program continues a high level of activity, with projects being conducted by graduate students and faculty advisors in the Departments of Materials Science and Engineering, Civil Engineering and Applied Mechanics, and Mechanical and Aerospace Engineering at the University of Virginia. This work is funded by the NASA-Langley Research Center under Grant NAG-1-745. We report on progress achieved between July 1 and December 31, 1992. The objective of the LA(2)ST Program is to conduct interdisciplinary graduate student research on the performance of next generation, light weight aerospace alloys, composites and thermal gradient structures in collaboration with NASA-Langley researchers. Specific technical objectives are presented for each research project. We generally aim to produce relevant data and basic understanding of material mechanical response, corrosion behavior, and microstructure; new monolithic and composite alloys; advanced processing methods; new solid and fluid mechanics analyses; measurement advances; and critically, a pool of educated graduate students for aerospace technologies.

Contracts, grants and funding summary of supersonic cruise research and variable-cycle engine technology programs, 1972 - 1982

Science.gov (United States)

Hoffman, S.; Varholic, M. C.

1983-01-01

NASA-SCAR (AST) program was initiated in 1972 at the direct request of the Executive Office of the White House and Congress following termination of the U.S. SST program. The purpose of SCR was to conduct a focused research and technology program on those technology programs which contributed to the SST termination and, also, to provide an expanded data base for future civil and military supersonic transport aircraft. Funding for the Supersonic Cruise Research (SCR) Program was initiated in fiscal year 1973 and terminated in fiscal year 1981. The program was implemented through contracts and grants with industry, universities, and by in-house investigations at the NASA/OAST centers. The studies included system studies and five disciplines: propulsion, stratospheric emissions impact, materials and structures, aerodynamic performance, and stability and control. The NASA/Lewis Variable-Cycle Engine (VCE) Component Program was initiated in 1976 to augment the SCR program in the area of propulsion. After about 2 years, the title was changed to VCE Technology program. The total number of contractors and grantees on record at the AST office in 1982 was 101 for SCR and 4 for VCE. This paper presents a compilation of all the contracts and grants as well as the funding summaries for both programs.

Canada-Africa grants spur novel ideas, networks | IDRC ...

International Development Research Centre (IDRC) Digital Library (Canada)

2016-06-22

Jun 22, 2016 ... Canada-Africa grants spur novel ideas, networks ... networks involving African and Canadian academic researchers. ... Remarkable new research into HIV prevention among the "choice disabled" — vulnerable groups less ...

Sun Grant Initiative : great strides toward a sustainable and more energy-independent future

Science.gov (United States)

2014-09-01

The Sun Grant Initiative publication, developed by the U.S. Department of Transportation, offers a glimpse of how the Sun Grant Initiative Centers are advancing alternative fuels research. Transportation plays a significant role in biofuels research,...

School Integrated Pest Management (IPM) Grants

Science.gov (United States)

EPA's IPM in schools grant program supports projects that include research, development, monitoring, public education, training, demonstrations, or studies to support recipients’ efforts to increase IPM adoption by public and tribal schools (K-12).

Analysis of a closed-kinematic chain robot manipulator

Science.gov (United States)

Nguyen, Charles C.; Pooran, Farhad J.

1988-01-01

Presented are the research results from the research grant entitled: Active Control of Robot Manipulators, sponsored by the Goddard Space Flight Center (NASA) under grant number NAG-780. This report considers a class of robot manipulators based on the closed-kinematic chain mechanism (CKCM). This type of robot manipulators mainly consists of two platforms, one is stationary and the other moving, and they are coupled together through a number of in-parallel actuators. Using spatial geometry and homogeneous transformation, a closed-form solution is derived for the inverse kinematic problem of the six-degree-of-freedom manipulator, built to study robotic assembly in space. Iterative Newton Raphson method is employed to solve the forward kinematic problem. Finally, the equations of motion of the above manipulators are obtained by employing the Lagrangian method. Study of the manipulator dynamics is performed using computer simulation whose results show that the robot actuating forces are strongly dependent on the mass and centroid locations of the robot links.

The Bill & Melinda Gates Foundation's grant-making programme for global health.

Science.gov (United States)

McCoy, David; Kembhavi, Gayatri; Patel, Jinesh; Luintel, Akish

2009-05-09

The Bill & Melinda Gates Foundation is a major contributor to global health; its influence on international health policy and the design of global health programmes and initiatives is profound. Although the foundation's contribution to global health generally receives acclaim, fairly little is known about its grant-making programme. We undertook an analysis of 1094 global health grants awarded between January, 1998, and December, 2007. We found that the total value of these grants was US$8.95 billion, of which $5.82 billion (65%) was shared by only 20 organisations. Nevertheless, a wide range of global health organisations, such as WHO, the GAVI Alliance, the World Bank, the Global Fund to Fight AIDS, Tuberculosis and Malaria, prominent universities, and non-governmental organisations received grants. $3.62 billion (40% of all funding) was given to supranational organisations. Of the remaining amount, 82% went to recipients based in the USA. Just over a third ($3.27 billion) of funding was allocated to research and development (mainly for vaccines and microbicides), or to basic science research. The findings of this report raise several questions about the foundation's global health grant-making programme, which needs further research and assessment.

About the Office of Grants Administration

Science.gov (United States)

OGA supports grants and cooperative agreements awarded to scientific institutions, small businesses, and individuals to help build, maintain, and enhance a cohesive and comprehensive cancer research agenda. Learn more about OGA and its program structure.

A peroxisome proliferator-activated receptor ligand MCC-555 imparts anti-proliferative response in pancreatic cancer cells by PPARgamma-independent up-regulation of KLF4

Energy Technology Data Exchange (ETDEWEB)

Min, Kyung-Won [Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996 (United States); Zhang, Xiaobo [Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996 (United States); College of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi, 712100 (China); Imchen, Temjenmongla [Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996 (United States); Baek, Seung Joon, E-mail: sbaek2@utk.edu [Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996 (United States)

2012-09-01

MCC-555 is a novel PPARα/γ dual ligand of the thiazolidinedione class and was recently developed as an anti-diabetic drug with unique properties. MCC-555 also has anti-proliferative activity through growth inhibition and apoptosis induction in several cancer cell types. Our group has shown that MCC-555 targets several proteins in colorectal tumorigenesis including nonsteroidal anti-inflammatory drug (NSAID)-activated gene (NAG-1) which plays an important role in chemoprevention responsible for chemopreventive compounds. NAG-1 is a member of the TGF-β superfamily and is involved in tumor progression and development; however, NAG-1's roles in pancreatic cancer have not been studied. In this report, we found that MCC-555 alters not only NAG-1 expression, but also p21 and cyclin D1 expression. NAG-1 and p21 expression was not blocked by PPARγ-specific antagonist GW9662, suggesting that MCC-555-induced NAG-1 and p21 expression is independent of PPARγ activation. However, decreasing cyclin D1 by MCC-555 seems to be affected by PPARγ activation. Further, we found that the GC box located in the NAG-1 promoter play an important role in NAG-1 transactivation by MCC-555. Subsequently, we screened several transcription factors that may bind to the GC box region in the NAG-1 promoter and found that KLF4 potentially binds to this region. Expression of KLF4 precedes NAG-1 and p21 expression in the presence of MCC-555, whereas blocking KLF4 expression using specific KLF4 siRNA showed that both NAG-1 and p21 expression by MCC-555 was blocked. In conclusion, MCC-555's actions on anti-proliferation involve both PPARγ-dependent and -independent pathways, thereby enhancing anti-tumorigenesis in pancreatic cancer cells. -- Highlights: ► PPARα/γ ligand MCC-555 exhibits anti-proliferative activity in pancreatic cancer cells. ► MCC-555 affects KLF4 expression following by NAG-1 and p21 expression in a PPARγ independent manner. ► MCC-555 also affects cyclin D1 down

A peroxisome proliferator-activated receptor ligand MCC-555 imparts anti-proliferative response in pancreatic cancer cells by PPARgamma-independent up-regulation of KLF4

International Nuclear Information System (INIS)

Min, Kyung-Won; Zhang, Xiaobo; Imchen, Temjenmongla; Baek, Seung Joon

2012-01-01

MCC-555 is a novel PPARα/γ dual ligand of the thiazolidinedione class and was recently developed as an anti-diabetic drug with unique properties. MCC-555 also has anti-proliferative activity through growth inhibition and apoptosis induction in several cancer cell types. Our group has shown that MCC-555 targets several proteins in colorectal tumorigenesis including nonsteroidal anti-inflammatory drug (NSAID)-activated gene (NAG-1) which plays an important role in chemoprevention responsible for chemopreventive compounds. NAG-1 is a member of the TGF-β superfamily and is involved in tumor progression and development; however, NAG-1's roles in pancreatic cancer have not been studied. In this report, we found that MCC-555 alters not only NAG-1 expression, but also p21 and cyclin D1 expression. NAG-1 and p21 expression was not blocked by PPARγ-specific antagonist GW9662, suggesting that MCC-555-induced NAG-1 and p21 expression is independent of PPARγ activation. However, decreasing cyclin D1 by MCC-555 seems to be affected by PPARγ activation. Further, we found that the GC box located in the NAG-1 promoter play an important role in NAG-1 transactivation by MCC-555. Subsequently, we screened several transcription factors that may bind to the GC box region in the NAG-1 promoter and found that KLF4 potentially binds to this region. Expression of KLF4 precedes NAG-1 and p21 expression in the presence of MCC-555, whereas blocking KLF4 expression using specific KLF4 siRNA showed that both NAG-1 and p21 expression by MCC-555 was blocked. In conclusion, MCC-555's actions on anti-proliferation involve both PPARγ-dependent and -independent pathways, thereby enhancing anti-tumorigenesis in pancreatic cancer cells. -- Highlights: ► PPARα/γ ligand MCC-555 exhibits anti-proliferative activity in pancreatic cancer cells. ► MCC-555 affects KLF4 expression following by NAG-1 and p21 expression in a PPARγ independent manner. ► MCC-555 also affects cyclin D1 down

Academic Talent Selection in Grant Review Panels

NARCIS (Netherlands)

Arensbergen, P. van; Weijden, I. van der; Besselaar, P van den; Prpic, K.; Weijden, I. van der; Aseulova, N.

2014-01-01

Career grants are an important instrument for selecting and stimulating the next generation of leading researchers. Earlier research has mainly focused on the relation between past performance and success. In this study we investigate the evidence of talent and how the selection process takes place.

Grants Process Overview

Science.gov (United States)

This infographic shows the steps in the National Institutes of Health and National Cancer Institute Grants Process. The graphic shows which steps are done by the Principle Investigator, Grantee Institution, and by NIH. The process is represented by a circular flow of steps. Starting from the top and reading clockwise: The Principle Investigator “Initiates Research Idea and Prepares Application” The Grantee Institution “Submits Application” NIH “NIH Center For Scientific Review, Assigns To NCI And To Study Section” NIH “Scientific Review Group (NCI OR CSR) Evaluates for Scientific Merit” NIH “National Cancer Advisory Board Recommends Action” NIH “NCI Evaluates Program Relevance And Need” NIH “NCI Makes Funding Selections And Issues Grant Awards” (NIH) NIH “NCI Monitors Programmatic and Business Management Performance of the Grant” The Grantee Institution “Manages Funds” The Principle Investigator “Conducts Research” Source: www.cancer.gov Icons made by Freepik from http://www.flaticon.com is licensed by CC BY3.0”

To apply or not to apply: a survey analysis of grant writing costs and benefits.

Science.gov (United States)

von Hippel, Ted; von Hippel, Courtney

2015-01-01

We surveyed 113 astronomers and 82 psychologists active in applying for federally funded research on their grant-writing history between January, 2009 and November, 2012. We collected demographic data, effort levels, success rates, and perceived non-financial benefits from writing grant proposals. We find that the average proposal takes 116 PI hours and 55 CI hours to write; although time spent writing was not related to whether the grant was funded. Effort did translate into success, however, as academics who wrote more grants received more funding. Participants indicated modest non-monetary benefits from grant writing, with psychologists reporting a somewhat greater benefit overall than astronomers. These perceptions of non-financial benefits were unrelated to how many grants investigators applied for, the number of grants they received, or the amount of time they devoted to writing their proposals. We also explored the number of years an investigator can afford to apply unsuccessfully for research grants and our analyses suggest that funding rates below approximately 20%, commensurate with current NIH and NSF funding, are likely to drive at least half of the active researchers away from federally funded research. We conclude with recommendations and suggestions for individual investigators and for department heads.

To apply or not to apply: a survey analysis of grant writing costs and benefits.

Directory of Open Access Journals (Sweden)

Ted von Hippel

Full Text Available We surveyed 113 astronomers and 82 psychologists active in applying for federally funded research on their grant-writing history between January, 2009 and November, 2012. We collected demographic data, effort levels, success rates, and perceived non-financial benefits from writing grant proposals. We find that the average proposal takes 116 PI hours and 55 CI hours to write; although time spent writing was not related to whether the grant was funded. Effort did translate into success, however, as academics who wrote more grants received more funding. Participants indicated modest non-monetary benefits from grant writing, with psychologists reporting a somewhat greater benefit overall than astronomers. These perceptions of non-financial benefits were unrelated to how many grants investigators applied for, the number of grants they received, or the amount of time they devoted to writing their proposals. We also explored the number of years an investigator can afford to apply unsuccessfully for research grants and our analyses suggest that funding rates below approximately 20%, commensurate with current NIH and NSF funding, are likely to drive at least half of the active researchers away from federally funded research. We conclude with recommendations and suggestions for individual investigators and for department heads.

76 FR 37191 - Notice of Competition for University Transportation Centers (UTC) Program Grants

Science.gov (United States)

2011-06-24

... capability, the use of peer review, and effective partnerships to advance diversity. The Research and... Competition for University Transportation Centers (UTC) Program Grants AGENCY: Research and Innovative... conduct a competition for University Transportation Centers (UTC) Program grants for the purpose of...

Shifting Demographics among Research Project Grant Awardees at the National Heart, Lung, and Blood Institute (NHLBI.

Directory of Open Access Journals (Sweden)

Marc F Charette

Full Text Available The present study was initiated because of concerns expressed by NHLBI-funded mid-career investigators regarding perceived difficulties in the renewal of their grant awards. This led us to ask: "Are mid-career investigators experiencing disproportionate difficulties in the advancement of their professional careers?" Our portfolio analysis indicates that there has been a significant and evolving shift in the demographics of research project grant (RPG awardees at NHLBI. In 1998, mid-career (ages 41-55 investigators constituted approximately 60% of all investigators with the remaining 40% being equally divided between early-stage (ages 24-40 investigators and established (ages 56 to 70 and older investigators. However, since 1998, the proportion of established RPG awardees has been increasing in a slowly progressive and strikingly linear fashion. At the same time the proportion of early-stage awardees fell precipitously until 2006 and then stabilized. During the same period, the proportion of mid-career awardees, which had been relatively stable through 2006, began to fall significantly. In examining potential causes of these demographic shifts we have identified certain inherent properties within the RPG award system that appear to promote an increasingly more established awardee population and a persistent decrease in the proportion of mid-career investigators. A collateral result of these demographic shifts, when combined with level or declining funding, is a significant reduction in the number of RPG awards received by NHLBI mid-career investigators and a corresponding decrease in the number of independent research laboratories.

42 CFR 63a.4 - Who is eligible for a training grant?

Science.gov (United States)

2010-10-01

... in cooperation with, the Pan American Health Organization or the World Health Organization. ...) International training grants for AIDS research. Any international organization concerned with public health is..., preference shall be given to: (1) Training activities conducted by, or in cooperation with, the World Health...

Researcher Story: Stuttering

Medline Plus

Full Text Available ... Toolkits Grants & Funding Grants Home Page Funding Forms Library Due Dates How to Apply About Grants Policy & ... Education Research in NIH Labs & Clinics Training Opportunities Library Resources Research Resources Clinical Research Resources Safety, Regulation ...

Bridging Grant : Building Canadian Support for Global Health ...

International Development Research Centre (IDRC) Digital Library (Canada)

The Canadian Coalition for Global Health Research (CCGHR) is a not-for-profit organization dedicated to supporting research for global health equity. The CCGHR provides a networking and action platform for the Canadian global health research community and partners in low- and middle-income countries. This grant will ...

25 CFR 23.22 - Purpose of tribal government grants.

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Purpose of tribal government grants. 23.22 Section 23.22... Grants to Indian Tribes for Title II Indian Child and Family Service Programs § 23.22 Purpose of tribal government grants. (a) Grants awarded under this subpart are for the establishment and operation of tribally...

Rapid chromatographic separation of dissoluble Ag(I) and silver-containing nanoparticles of 1-100 nanometer in antibacterial products and environmental waters.

Science.gov (United States)

Zhou, Xiao-Xia; Liu, Rui; Liu, Jing-Fu

2014-12-16

Sensitive and rapid methods for speciation analysis of nanoparticulate Ag (NAg) and Ag(I) in complex matrices are urgently needed for understanding the environmental effects and biological toxicity of silver nanoparticles (AgNPs). Herein we report the development of a universal liquid chromatography (LC) method for rapid and high resolution separation of dissoluble Ag(I) from nanoparticles covering the entire range of 1-100 nm in 5 min. By using a 500 Å poresize amino column, and an aqueous mobile phase containing 0.1% (v/v) FL-70 (a surfactant) and 2 mM Na2S2O3 at a flow rate of 0.7 mL/min, all the nanoparticles of various species such as Ag and Ag2S were eluted in one fraction, while dissoluble Ag(I) was eluted as a baseline separated peak. The dissoluble Ag(I) was quantified by the online coupled ICP-MS with a detection limit of 0.019 μg/L. The NAg was quantified by subtracting the dissoluble Ag(I) from the total Ag content, which was determined by ICP-MS after digestion of the sample without LC separation. While the addition of FL-70 and Na2S2O3 into the mobile phase is essential to elute NAg and Ag(I) from the column, the use of 500 Å poresize column is the key to baseline separation of Ag(I) from ∼ 1 nm AgNPs. The feasibility of the proposed method was demonstrated in speciation analysis of dissoluble Ag(I) and NAg in antibacterial products and environmental waters, with very good chromatographic repeatability (relative standard deviations) in both peak area (<2%) and retention time (<0.6%), excellent spiked recoveries in the range of 84.7-102.7% for Ag(I) and 81.3-106.3% for NAg. Our work offers a novel approach to rapid and baseline separation of dissoluble metal ions from their nanoparticulate counterparts covering the whole range of 1-100 nm.

DOE Matching Grant Program

International Nuclear Information System (INIS)

Tsoukalas, L.

2002-01-01

Funding used to support a portion of the Nuclear Engineering Educational Activities. Upgrade of teaching labs, student support to attend professional conferences, salary support for graduate students. The US Department of Energy (DOE) has funded Purdue University School of Nuclear Engineering during the period of five academic years covered in this report starting in the academic year 1996-97 and ending in the academic year 2000-2001. The total amount of funding for the grant received from DOE is $416K. In the 1990's, Nuclear Engineering Education in the US experienced a significant slow down. Student enrollment, research support, number of degrees at all levels (BS, MS, and PhD), number of accredited programs, University Research and Training Reactors, all went through a decline to alarmingly low levels. Several departments closed down, while some were amalgamated with other academic units (Mechanical Engineering, Chemical Engineering, etc). The School of Nuclear Engineering at Purdue University faced a major challenge when in the mid 90's our total undergraduate enrollment for the Sophomore, Junior and Senior Years dropped in the low 30's. The DOE Matching Grant program greatly strengthened Purdue's commitment to the Nuclear Engineering discipline and has helped to dramatically improve our undergraduate and graduate enrollment, attract new faculty and raise the School of Nuclear Engineering status within the University and in the National scene (our undergraduate enrollment has actually tripled and stands at an all time high of over 90 students; total enrollment currently exceeds 110 students). In this final technical report we outline and summarize how the grant was expended at Purdue University

Review of research grant allocation to psychosocial studies in diabetes research

DEFF Research Database (Denmark)

Jones, A; Vallis, Michael; Cooke, Debbie

2016-01-01

AIMS: To estimate and discuss the allocation of diabetes research funds to studies with a psychosocial focus. METHODS: Annual reports and funded-research databases from approximately the last 5 years (if available) were reviewed from the following representative funding organizations, the American...... Diabetes Association, the Canadian Diabetes Association, Diabetes Australia, Diabetes UK, the Dutch Diabetes Research Foundation and the European Foundation for the Study of Diabetes, in order to estimate the overall proportion of studies allocated research funding that had a psychosocial focus. RESULTS......: An estimated mean of 8% of funded studies from our sample were found to have a psychosocial focus. CONCLUSIONS: The proportion of funded studies with a psychosocial focus was small, with an estimated mean ratio of 17:1 observed between funded biomedical and psychosocial studies in diabetes research. While...

Small grant management in health and behavioral sciences: Lessons learned.

Science.gov (United States)

Sakraida, Teresa J; D'Amico, Jessica; Thibault, Erica

2010-08-01

This article describes considerations in health and behavioral sciences small grant management and describes lessons learned during post-award implementation. Using the components by W. Sahlman [Sahlman, W. (1997). How to write a great business plan. Harvard Business Review, 75(4), 98-108] as a business framework, a plan was developed that included (a) building relationships with people in the research program and with external parties providing key resources, (b) establishing a perspective of opportunity for research advancement, (c) identifying the larger context of scientific culture and regulatory environment, and (d) anticipating problems with a flexible response and rewarding teamwork. Small grant management included developing a day-to-day system, building a grant/study program development plan, and initiating a marketing plan. Copyright 2010 Elsevier Inc. All rights reserved.

Nuclear Structure Committee annual report 1976-1977, nuclear structure grants and laboratory agreements

International Nuclear Information System (INIS)

1977-01-01

The Annual Report for the period 1 August 1976 to 31 July 1977 of the Nuclear Structure Committee of the Nuclear Physics Board, under the (United Kingdom) Science Research Council, is presented. Details are given of nuclear structure grants and laboratory agreements. (U.K.)

Particle Physics Committee annual report 1976-77, particle physics grants and laboratory agreements

International Nuclear Information System (INIS)

1977-01-01

The Annual Report for the period 1 August 1976 to 31 July 1977 of the Particel Physics Committee of the Nuclear Physics Board, under the (United Kingdom) Science Research Council, is presented. Details are given of particle physics grants and laboratory agreements. (U.K.)

42 CFR 137.25 - Are planning and negotiation grants available?

Science.gov (United States)

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Are planning and negotiation grants available? 137... for Participation in Self-Governance Planning Phase § 137.25 Are planning and negotiation grants... planning and negotiation grants available, an explanation of the application process for such grants, and...

Small Business Innovation Research: Abstracts of Phase 1 awards, 1994

Energy Technology Data Exchange (ETDEWEB)

1994-12-31

The Small Business Innovation Research (SBIR) program enables DOE to obtain effective, innovative solutions to important problems through the private sector, which has a commercial incentive to pursue the resulting technology and bring it to the marketplace. The growing number of awardees, many of them started in business in response to SBIR solicitations, is becoming a significant resource for the solution of high risk, high technology problems for the Department. As detailed here, this publication describes the technical efforts for SBIR Phase 1 awards in 1994. It is intended for the educated layman, and may be of particular interest to potential investors who wish to get in on the ground floor of exciting opportunities. Contained in this booklet are abstracts of the Phase 1 awards made in FY 1994 under the DOE SBIR program. The 212 Phase 1 projects described here were selected in a highly competitive process from a total of 2,276 grant applications received in response to the 1994 DOE annual SBIR Solicitation. The selections for awards were made on scientific and technical merit, as judged against the specific criteria listed in the Solicitation. Conclusions were reached on the basis of detailed reports returned by reviewers drawn from DOE laboratories, universities, private industry, and government. (Any discrepancies noted in prior DOE releases naming the firms selected for awards are due either to the firm changing its name after the award selection or to the firm not proceeding to a signed grant.) It is expected that between one-third and one-half of the Phase 1 projects will be continued into Phase 2. The work described in the abstracts is novel, high-risk research, but the benefits will also be potentially high if the objectives are met. Brief comments on the potential applications are given after each abstract. Individuals and organizations with an interest in the research described are encouraged to contact the appropriate small business directly.

Microvegetation on the top of Mt. Roraima, Venezuela

Czech Academy of Sciences Publication Activity Database

Kaštovský, J.; Fučíková, K.; Hauer, Tomáš; Bohunická, M.

2011-01-01

Roč. 11, č. 1 (2011), 171-186 ISSN 1802-5439 R&D Projects: GA ČR GA206/08/0318 Institutional research plan: CEZ:AV0Z60050516 Keywords : cyanobacteria * algae * Roraima Subject RIV: EF - Botanics Impact factor: 1.327, year: 2011

Business grants

Science.gov (United States)

Twelve small businesses who are developing equipment and computer programs for geophysics have won Small Business Innovative Research (SBIR) grants from the National Science Foundation for their 1989 proposals. The SBIR program was set up to encourage the private sector to undertake costly, advanced experimental work that has potential for great benefit.The geophysical research projects are a long-path intracavity laser spectrometer for measuring atmospheric trace gases, optimizing a local weather forecast model, a new platform for high-altitude atmospheric science, an advanced density logging tool, a deep-Earth sampling system, superconducting seismometers, a phased-array Doppler current profiler, monitoring mesoscale surface features of the ocean through automated analysis, krypton-81 dating in polar ice samples, discrete stochastic modeling of thunderstorm winds, a layered soil-synthetic liner base system to isolate buildings from earthquakes, and a low-cost continuous on-line organic-content monitor for water-quality determination.

78 FR 45973 - Brookwood-Sago Mine Safety Grants

Science.gov (United States)

2013-07-30

... CFR Part 36, Nondiscrimination on the basis of sex in education programs or activities receiving... MSHA logo may be applied to the grant-funded material including posters, videos, pamphlets, research...

Grant Peer Review: Improving Inter-Rater Reliability with Training.

Science.gov (United States)

Sattler, David N; McKnight, Patrick E; Naney, Linda; Mathis, Randy

2015-01-01

This study developed and evaluated a brief training program for grant reviewers that aimed to increase inter-rater reliability, rating scale knowledge, and effort to read the grant review criteria. Enhancing reviewer training may improve the reliability and accuracy of research grant proposal scoring and funding recommendations. Seventy-five Public Health professors from U.S. research universities watched the training video we produced and assigned scores to the National Institutes of Health scoring criteria proposal summary descriptions. For both novice and experienced reviewers, the training video increased scoring accuracy (the percentage of scores that reflect the true rating scale values), inter-rater reliability, and the amount of time reading the review criteria compared to the no video condition. The increase in reliability for experienced reviewers is notable because it is commonly assumed that reviewers--especially those with experience--have good understanding of the grant review rating scale. The findings suggest that both experienced and novice reviewers who had not received the type of training developed in this study may not have appropriate understanding of the definitions and meaning for each value of the rating scale and that experienced reviewers may overestimate their knowledge of the rating scale. The results underscore the benefits of and need for specialized peer reviewer training.

Getting a Grant: Sources of Funding and How To Pursue Them

Science.gov (United States)

Lum, Christie

2005-01-01

There are many different agencies and organizations which provide funding for those involved in research, community development, education, the provision of health and social services, and other activities. This publication is designed to serve as an introduction for counselors to sources of grant funding and particular grant programs, and to the…

Commerce, Research and Education: Contributions and Challenges of Marine Extension Work in NOAA Sea Grant Program-Puerto Rico, Michigan and National office

Science.gov (United States)

Aleman Diaz, A.

2006-12-01

The National Sea Grant program represents NOAA's nationwide university-based program in support of coastal resource use and conservation. This program is composed of 30 university-based programs that work with local coastal communities. This study focuses on a historical and multi-sited ethnographic approach that analyzes two Sea Grant Programs and their connection to the overarching NOAA national goals from 1980- 2000.The project aims to offer insight on how the extension agent position facilitates the resolution of coastal and marine management and tourism issues. The extension agents are staff who have an extensive knowledge of available coastal resources and have the role of translating this information to coastal stakeholders. Additionally, these agents assess the needs of coastal communities and report back to the program making their role into a position that can effectively alter and/or contribute to institutional and environmental management programs at broader, cross-country and global levels. The extension programs in Michigan and Puerto Rico were examined to understand how local programs respond to cultural and regional processes shaping marine extension and the management of issues faced by coastal stakeholders. A total of 36 semi- structured in-depth interviews were completed at each site, to address the following questions: (1) How do extension agents view their role at the Puerto Rico and Michigan offices and in the Sea Grant program? How do they view the conditions of their work? (2) How do their views compare to the accomplishments by each Sea Grant administration and internal inquiries? How do their views reveal conditions documented in Puerto Rico and Michigan (e.g., social, cultural, political, economic, etc)? (3) What kind of strategies do agents develop for the management of specific coastal and tourism related projects? (4) How do the Puerto Rico and Michigan offices coordinate their work, and collaborate with other "college" programs and

Research in high energy elementary particle physics: Annual progress report, [March 1, 1986-February 29, 1988

International Nuclear Information System (INIS)

Field, R.; Ramond, P.; Thorn, C.; Avery, P.; Walker, J.; Tanner, D.; Sikivie, P.; Sullivan, N.; Majeswki, S.

1988-01-01

This is a progress report covering the period March 1, 1986 through February 29, 1988 for the High Energy Physics program at the University of Florida (DOE Florida Demonstration Project grant FG05-86-ER40272). Our research program covers a braod range of topics in theoretical and experimental physics and includes detector development and an Axion search. Included in this report is a summary of our program and a discussion of the research progress

Using Randomized Clinical Trials to Determine the Impact of Reading Intervention on Struggling Adolescent Readers: Reports of Research from Five Nationally Funded Striving Readers Grants

Science.gov (United States)

Loadman, William; Sprague, Kim; Hamilton, Jennifer; Coffey, Deb; Faddis, Bonnie

2010-01-01

In 2005, the U.S. Department of Education awarded eight Striving Readers grants to projects around the country. The goal of Striving Readers is to improve literacy skills and achievement for struggling readers in middle and high school and to increase the research base using randomized clinical research to address improvement in adolescent…

Effect of storage time at -20°C on markers used for assessment of renal damage in children: albumin, γ-glutamyl transpeptidase, N-acetyl-β-D-glucosaminidase and α1-microglobulin.

Science.gov (United States)

Trachtenberg, Felicia; Barregard, Lars

2010-11-01

The objective of this study is to examine the influence of storage time at -20°C on the concentration of albumin, γ-glutamyl transpeptidase (γ-GT), N-acetyl-β-D-glucosaminidase (NAG), α(1)-microglobulin (A1M) and creatinine in a large sample of healthy children. The New England Children's Amalgam Trial followed 534 children, aged 6-10 at baseline, for 5 years, with annual urine collections. Urine samples were analysed for creatinine, albumin, γ-GT, NAG and A1M concentrations. Repeated measures analysis of covariance was used to model the effect of storage time on these concentrations. The γ-GT concentration decreased significantly with storage time at -20°C. There was also a limited decrease in NAG. Albumin, A1M and creatinine concentrations did not appear to be affected by storage time at -20°C. If it is necessary to interpret results from samples stored for a long time at -20°C, it is advisable to account for storage time in statistical models.

N-acetylglutamate synthase deficiency: Novel mutation associated with neonatal presentation and literature review of molecular and phenotypic spectra

Directory of Open Access Journals (Sweden)

Eiman H. Al Kaabi

2016-09-01

Full Text Available The urea cycle is the main pathway for the disposal of excess nitrogen. Carbamoylphosphate synthetase 1 (CPS1, the first and rate-limiting enzyme of urea cycle, is activated by N-acetylglutamate (NAG, and thus N-acetylglutamate synthase (NAGS is an essential part of the urea cycle. Although NAGS deficiency is the rarest urea cycle disorder, it is the only one that can be specifically and effectively treated by a drug, N-carbamylglutamate, a stable structural analogous of NAG that activates CPS1. Here we report an infant with NAGS deficiency who presented with neonatal hyperammonemia. She was found to have a novel homozygous splice-site mutation, c.1097-2A>T, in the NAGS gene. We describe the clinical course of this infant, who had rapid response to N-carbamylglutamate treatment. In addition, we reviewed the clinical and molecular spectra of previously reported individuals with NAGS deficiency, which presents in most cases with neonatal hyperammonemia, and in some cases the presentation is later, with a broad spectrum of ages and manifestations. With this broad later-onset phenotypic spectrum, maintaining a high index of suspicion is needed for the early diagnosis of this treatable disease.

Diversity of cyanobacteria in man-made solar saltern, Petchaburi Province, Thailand - a pilot study.

Czech Academy of Sciences Publication Activity Database

Chatchawan, T.; Peerapornpisal, Y.; Komárek, Jiří

2011-01-01

Roč. 11, č. 1 (2011), 203-214 ISSN 1802-5439 R&D Projects: GA ČR GA206/08/0318 Institutional research plan: CEZ:AV0Z60050516 Keywords : biodiversity of cyanobacteria * solar salterns * Thailand Subject RIV: EF - Botanics Impact factor: 1.327, year: 2011

19 CFR 351.504 - Grants.

Science.gov (United States)

2010-04-01

... INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE ANTIDUMPING AND COUNTERVAILING DUTIES Identification and Measurement of Countervailable Subsidies § 351.504 Grants. (a) Benefit. In the case of a grant, a benefit exists in the amount of the grant. (b) Time of receipt of benefit. In the case of a grant, the...

Choix d'un modèle de pyrolyse ménagée du bois à l'échelle de la microparticule en vue de la modélisation macroscopique

OpenAIRE

Rousset , Patrick; Turner , Ian; Donnot , Andre; Perre , Patrick

2006-01-01

Par définition la pyrolyse ménagée du bois est la décomposition physique et chimique de matières organiques sous l'action de la chaleur et en absence d'oxygène. Comprendre ce phénomène passe d'abord par l'identification des mécanismes réactionnels et la détermination des paramètres cinétiques mis en jeu lors de la dégradation thermique du bois et de ses constituants majeurs, c'est-à-dire cellulose, hémicelluloses et lignines. La richesse et la diversité des résultats issus de la littérature s...

7 CFR 2.66 - Administrator, Cooperative State Research, Education, and Extension Service.

Science.gov (United States)

2010-01-01

... extension program through grants to regional rural development centers and competitive grants to land-grant... Small Business Innovation Development Act of 1982 for USDA (15 U.S.C. 638(e)-(k)). (51) Administer a..., and Extension Service. (1) Administer research and technology development grants related to the...

Effect of diclofenac sodium on the level of non-steroidal anti-inflammatory drug-activated gene-1 in patients with post-ERCP pancreatitis

Directory of Open Access Journals (Sweden)

HU Cui

2018-03-01

Full Text Available ObjectiveTo investigate the effect of diclofenac sodium on the level of non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1 in patients with post-ERCP pancreatitis (PEP. MethodsA total of 120 patients who underwent ERCP in The First Affiliated Hospital of Anhui Medical University from September 2012 to October 2013 were enrolled and randomly divided into diclofenac sodium group and control group, with 60 patients in each group. The patients in the diclofenac sodium group were given intramuscular injection of Olfen (containing diclofenac sodium 75 mg immediately after ERCP. Blood samples were collected before surgery and at 3 and 24 hours after surgery, and the level of amylase was measured. The incidence of abdominal pain was also observed and the incidence rate of PEP was calculated for both groups. RT-PCR and Western blot were used to measure the mRNA and protein expression of NAG-1 in plasma. An repeated-measures analysis of variance was used for comparison of continuous data, a univariate analysis of variance was used for data meeting the requirements of sphericity test, and the Greenhouse-Geisser correction method was used for data which did not meet the requirements of sphericity test. The chi-square test was used for comparison of categorical data between groups. ResultsThe diclofenac sodium group had a significantly lower incidence rate of PEP than the control group ［6.67% (4/60 vs 20.00% (12/60, χ2=4.62, P=0.03］. The diclofenac sodium group had a significantly lower level of amylase than the control group at 3 and 24 hours after surgery (at 3 hours after surgery: 202.70±120.44 U/L vs 283.57±178.39 U/L, t=2.06, P＜0.05, at 24 hours after surgery: 209.13±157.14 U/L vs 30597±20869 U/L, t=2.03, P＜0.05. At 3 hours after ERCP, the diclofenac sodium group had significant increases in the mRNA and protein expression of NAG-1 in plasma and significantly higher mRNA and protein expression of NAG-1 than the control group

Evaluating public involvement in research design and grant development: Using a qualitative document analysis method to analyse an award scheme for researchers.

Science.gov (United States)

Baxter, Susan; Muir, Delia; Brereton, Louise; Allmark, Christine; Barber, Rosemary; Harris, Lydia; Hodges, Brian; Khan, Samaira; Baird, Wendy

2016-01-01

The National Institute for Health Research (NIHR) Research Design Service (RDS) for Yorkshire and Humber has been running a public involvement funding scheme since 2008. This scheme awards researchers a small amount of money to help them get involvement from patients and/or the public. Involvement activities take place at the time when researchers are planning studies, and when they are completing application forms to request funding for a proposed research project. After the public involvement activities researchers are asked to write a report for the RDS describing what they did with the public involvement funding. This study analysed those reports using an approach which included members of a public involvement panel in the data analysis process. The aim of the work was to see what the views and experiences of researchers who received funding were, and what might be learned for the future of the scheme. Twenty five reports were analysed. Four main themes were identified, these described: the added value of public involvement; aspects to consider when planning and designing public involvement; different roles of public contributors; and aspects of valuing public member contributions. The group approach to analysis was successful in enabling involvement of a variety of individuals in the process. The findings of the study provide evidence of the value of public involvement during the development of applications for research funding. The results also indicate that researchers recognise the variety in potential roles for the public in research, and acknowledge how involvement adds value to studies. Background A regional Research Design Service, funded by the National Institute for Health Research, introduced a small grant in 2008, to support public involvement (often known as patient and public involvement [PPI]) activities during the development of applications for research funding. Successful applicants are requested to submit a report detailing how the grant

FEMA Grants Program Directorate - Preparedness (Non-Disaster) and Assistance to Firefighter Grants

Data.gov (United States)

Department of Homeland Security — The Grant Programs Directorate (GPD) strategically and effectively administers and manages FEMA grants to ensure critical and measurable results for customers and...

Trends in funding for research on pain: a report on the National Institutes Of Health grant awards over the years 2003 to 2007.

Science.gov (United States)

Bradshaw, David H; Empy, Court; Davis, Phillip; Lipschitz, David; Dalton, Peter; Nakamura, Yoshio; Chapman, C Richard

2008-12-01

In recent years, the National Institutes of Health (NIH) has experienced unprecedented reductions in its customary annual budget increases. Consequently, researchers, health care policy planners and others have a pressing need for accurate information on NIH funding patterns. We created a unique and objective system for compiling, classifying, and analyzing data on NIH grant awards and funding for research on pain, nausea, and dyspnea using naïve observers, cross-validation by multiple raters, and face validation by experts. We present results of our method and analyses for the period from 2003 to 2007. Following a 12% increase from 2003 to 2004, funding for pain research fell by 9.4% per year on average over the next 3 years. The percent of the total NIH budget going to support pain research increased to 0.78% in 2004 but fell to 0.61% in 2007. A piecewise regression model confirmed the declining trend represented a significant fit to the data (R(2)=0.98, p=0.024). Separate breakdowns by Institutes showed similar patterns. Analyses of nausea and dyspnea research support revealed small but steady increases over the same period. Declining support for pain research disproportionate to decreases in the NIH budget signals a need for measures to promote funding for meritorious applications. Results of 5 year trends in numbers of grants and funding for research in pain, nausea, and dyspnea by the NIH show overall declines for pain but slight increases for nausea and dyspnea. Declining support for pain research that exceeds the reductions in the total NIH budget signals a need for measures to increase pain research funding.

Wetland Program Development Grants (WPDGs)

Data.gov (United States)

U.S. Environmental Protection Agency — The Wetland Grant Database (WGD) houses grant data for Wetland Program Development Grants (created by EPA in 1990 under the Clean Water Act Section 104(b)(3)...

Optical Fiber Spectroscopy

Science.gov (United States)

Buoncristiani, A. M.

1999-01-01

This is the final report of work done on NASA Grant NAG-1-443. The work covers the period from July 1, 1992 to December 1, 1998. During this period several distinct but related research studies and work tasks were undertaken. These different subjects are enumerated below with a description of the work done on each of them. The focus of the research was the development of optical fibers for use as distributed temperature and stress sensors. The initial concept was to utilize the utilize the temperature and stress dependence of emission from rare earth and transition metal ions substitutionally doped into crystalline or glass fibers. During the course of investigating this it became clear that fiber Bragg gratings provided a alternative for making the desired measurements and there was a shift of research focus on to include the photo-refractive properties of germano-silicate glasses used for most gratings and to the possibility of developing fiber laser sources for an integrated optical sensor in the research effort. During the course of this work several students from Christopher Newport University and other universities participated in this effort. Their names are listed below. Their participation was an important part of their education.

Canada-Africa grants spur novel ideas, networks | CRDI - Centre de ...

International Development Research Centre (IDRC) Digital Library (Canada)

22 juin 2016 ... Eric Smith. Short-term collaborations between Canadian and African researchers has generated compelling results on such pressing issues as maternal and child health, climate change impacts, and alternative energy sources. The Canada Africa Research Exchange Grants (CAREG) program fostered ...

Used energy-related laboratory equipment grant program for institutions of higher learning. Eligible equipment catalog

Energy Technology Data Exchange (ETDEWEB)

1994-07-01

This is a listing of energy related equipment available through the Energy-Related Laboratory Equipment Grant Program which grants used equipment to institutions of higher education for energy-related research. Information included is an overview of the program, how to apply for a grant of equipment, eligibility requirements, types of equipment available, and the costs for the institution.

22 CFR 64.10 - Grant not to constitute a gift.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Grant not to constitute a gift. 64.10 Section... EMPLOYEES IN CULTURAL EXCHANGE PROGRAMS OF FOREIGN COUNTRIES § 64.10 Grant not to constitute a gift. A grant made under an approved program shall not constitute a gift for purposes of 22 CFR 10.735-203 and...

Research in experimental nuclear physics: Progress report, April 1, 1988--March 31, 1989

International Nuclear Information System (INIS)

Moore, C.F.

1988-11-01

This report summarizes the work carried out by personnel from the University of Texas at Austin at the Los Alamos Clinton P. Anderson Meson Physics Facility (LAMPF) during the calendar year 1987 under grant AS05-87ER40343 between The University of Texas at Austin and the United States Department of Energy. The research activities involved experiments done with the Energetic Pion Channel and Spectrometer (EPICS), the Low Energy Pion Channel (LEP), the Pion and Particle Physics Channel (P 3 ), and the High Resolution Spectrometer (HRS). A brief overview of work supported by this grant is given. This report contains a list of abstracts of papers reported at scientific meetings, a list of invited papers, and a list of published papers and preprints. These papers summarize experiments undertaken in this grant period and indicate the work accomplished by the participants in this program of medium energy nuclear physics research. Much of the experimental work that has been attempted during the period covered by this report has either been published or submitted for publication. Also included is a list of the recent proposals on which we have participation at LAMPF, and a list of personnel who have participated in this research program

Do study grants help refugees find jobs? A case study of the effects of the voluntary sector grants on the education, training and employment of refugees in the United Kingdom

OpenAIRE

Ilmolelian, Peter

2005-01-01

Using the Africa Educational Trust (AET) as a case study, the primary aim of the research was to investigate whether or not the employment outcomes of those refugees who received financial grants to enable them attend their education/training courses were different from those who did not. 122 individuals who applied to AET for grants in 1993/94 were interviewed and data analysed using the Probit model and McNemar's Chi- squared test of significance. The study found that grant holders were mor...

Justice In Granting Remission For Corruption Prisoners A Review Of Indonesian Criminal Justice System

Directory of Open Access Journals (Sweden)

Mispansyah

2015-08-01

Full Text Available Abstract Prisoners are entitled to have a reduction in criminal past remission as stipulated in the Indonesian Criminal Justice System still being debated to this day. This research reviews the essence of the implementation of the substantive law in granting remission against inmate corruption cases from the perspective of public and individual interests. The type of research used in this paper is socio-legal research reviewing remission policy from the perspective of the criminal law system with philosophical and statute approach. The outcomes of the research indicate that the implementation of granting remission for corruption prisoners does not provide justice both procedural and substantive does not provide legal expediency and arising imbalance of justice for individuals communities and countries. The need to implement remissions with impartial justice for corruption prisoners in granting remission to be useful for individuals communities and countries.

Microwave and accelerator research. Final report on Grant DE-FG02-92ER40731

International Nuclear Information System (INIS)

Nation, John A.

2002-01-01

This report summarizes the main technical objectives and accomplishments during the life of the grant, and concludes with data on publications describing the research. The main activity was the development of very high power microwave sources, initially in X-band, and recent initial work on a Ka band TWT amplifier. There was additional activity on ferroelectric emitters. Highlights include the following: (1) The development of a relatively broad band microwave source yielding approx. 75 MW power at a power efficiency of 54% and an energy conversion efficiency of 43%. (2) The development of a ferroelectric cathode electron gun which yielded a beam current of up to 350 A at 500 kV. The device was shown to operate satisfactorily at a low repetition rate, limited by the available power supplies. The final beam power obtained exceeds that achieved elsewhere by several orders of magnitude. The gun development achieved was shown to give an electron beam suitable for high power X-band microwave sources with the demonstration of a 5-MW tunable X-band TWT single-stage amplifier. (3) Work was initiated on a Ka-Band TWT amplifier. Gains of over 30 dB were achieved at peak output powers of about 4 MW. Appendices include two submitted papers: Symmetric and asymmetric mode interaction in high-power traveling wave amplifiers: experiments and theory and High power microwave generation using a ferroelectric cathode electron gun

Strengthening Africa's science granting councils as champions of ...

International Development Research Centre (IDRC) Digital Library (Canada)

Science granting councils are central to funding and catalyzing research and innovation, particularly in national science systems in sub-Saharan Africa. The availability of reliable indicators—to monitor Africa's scientific and technological developments, implement science policies and strategies, track public investment in ...

Extension's Online Presence: Are Land-Grant Universities Promoting the Tripartite Mission?

Science.gov (United States)

Arnold, Shannon; Hill, Alexandra; Bailey, Nikki; Meyers, Courtney

2012-01-01

Land-grant universities were established with a tripartite mission: education, research, and outreach through the Cooperative Extension Service. The purpose of the study reported here was to evaluate the online presence and technological adoptions of Extension on land-grant university, college of agriculture, and state Extension websites. Almost…

Superfund Technical Assistance Grants

Data.gov (United States)

U.S. Environmental Protection Agency — This asset includes data related to the Superfund Technical Assistance Grant program, including grant number, award amounts, award dates, period of performance,...

42 CFR 59.9 - For what purpose may grant funds be used?

Science.gov (United States)

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false For what purpose may grant funds be used? 59.9 Section 59.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Project Grants for Family Planning Services § 59.9 For what purpose may...

A rapid and sensitive method for measuring N-acetylglucosaminidase activity in cultured cells.

Directory of Open Access Journals (Sweden)

Victor Mauri

Full Text Available A rapid and sensitive method to quantitatively assess N-acetylglucosaminidase (NAG activity in cultured cells is highly desirable for both basic research and clinical studies. NAG activity is deficient in cells from patients with Mucopolysaccharidosis type IIIB (MPS IIIB due to mutations in NAGLU, the gene that encodes NAG. Currently available techniques for measuring NAG activity in patient-derived cell lines include chromogenic and fluorogenic assays and provide a biochemical method for the diagnosis of MPS IIIB. However, standard protocols require large amounts of cells, cell disruption by sonication or freeze-thawing, and normalization to the cellular protein content, resulting in an error-prone procedure that is material- and time-consuming and that produces highly variable results. Here we report a new procedure for measuring NAG activity in cultured cells. This procedure is based on the use of the fluorogenic NAG substrate, 4-Methylumbelliferyl-2-acetamido-2-deoxy-alpha-D-glucopyranoside (MUG, in a one-step cell assay that does not require cell disruption or post-assay normalization and that employs a low number of cells in 96-well plate format. We show that the NAG one-step cell assay greatly discriminates between wild-type and MPS IIIB patient-derived fibroblasts, thus providing a rapid method for the detection of deficiencies in NAG activity. We also show that the assay is sensitive to changes in NAG activity due to increases in NAGLU expression achieved by either overexpressing the transcription factor EB (TFEB, a master regulator of lysosomal function, or by inducing TFEB activation chemically. Because of its small format, rapidity, sensitivity and reproducibility, the NAG one-step cell assay is suitable for multiple procedures, including the high-throughput screening of chemical libraries to identify modulators of NAG expression, folding and activity, and the investigation of candidate molecules and constructs for applications in

L130-million cut to grants hits UK physical scientists

CERN Multimedia

Cressey, Daniel

2008-01-01

"UK physicists, still reeling from massive funding cuts announced earlier this year, have learnt of worse to come. Roughly L130 million (US$260 million)is being slashed from research grants awarded by the Engineering and Physical Scienes Research Council (EPSRC), it announced on 17 March." (2 pages)

40 CFR 40.135-1 - Preapplication coordination.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Preapplication coordination. 40.135-1 Section 40.135-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE RESEARCH AND DEMONSTRATION GRANTS § 40.135-1 Preapplication coordination. (a) All applicants. (1...

TU-C-HORIZONS-01: The Expanding Horizons Travel Grant Program: ePosters and Discussion

International Nuclear Information System (INIS)

Siewerdsen, J; Jeraj, R

2016-01-01

The Expanding Horizons travel grant program provides opportunity for students and trainees to broaden the scope of scientific meetings they attend and gain insight from research outside traditional domains of medical physics. Through participation in such conferences, early-career researchers are introduced to new topics with relevance to medical physics research as a means to expand the scientific horizons of our discipline. This year, 21 Expanding Horizons travel grants were awarded, granting travel to 17 conferences, including: Radiomics, the World Molecular Imaging Society (WMIS), the 3D Printing Conference and Expo, the GPU Technology Conference, the SIAM Imaging Science Conference, the Human Brain Mapping Conference, the OSA Conference on Clinical and Translational Biophotonics, the Society for Neuroscience, the AACR Conference on Tumor Microenvironment, and the Conference on Knowledge Discovery and Data Mining. The Expanding Horizons electronic poster session gives a venue for AAPM conference attendees to meet and discuss with awardees, learn the hot topics and emerging research areas presented at these conferences, and understand the relevance to future medical physics research.

TU-C-HORIZONS-01: The Expanding Horizons Travel Grant Program: ePosters and Discussion

Energy Technology Data Exchange (ETDEWEB)

Siewerdsen, J [Johns Hopkins University, Baltimore, MD (United States); Jeraj, R [University of Wisconsin, Madison, WI (United States)

2016-06-15

The Expanding Horizons travel grant program provides opportunity for students and trainees to broaden the scope of scientific meetings they attend and gain insight from research outside traditional domains of medical physics. Through participation in such conferences, early-career researchers are introduced to new topics with relevance to medical physics research as a means to expand the scientific horizons of our discipline. This year, 21 Expanding Horizons travel grants were awarded, granting travel to 17 conferences, including: Radiomics, the World Molecular Imaging Society (WMIS), the 3D Printing Conference and Expo, the GPU Technology Conference, the SIAM Imaging Science Conference, the Human Brain Mapping Conference, the OSA Conference on Clinical and Translational Biophotonics, the Society for Neuroscience, the AACR Conference on Tumor Microenvironment, and the Conference on Knowledge Discovery and Data Mining. The Expanding Horizons electronic poster session gives a venue for AAPM conference attendees to meet and discuss with awardees, learn the hot topics and emerging research areas presented at these conferences, and understand the relevance to future medical physics research.

AUCC-IDRC Partnership Grant 2011-2013: New Models of ...

International Development Research Centre (IDRC) Digital Library (Canada)

The 2011-2013 grant will focus on the theme of new models of partnership. ... universities, and civil society or nongovernmental organizations in Canada and the South. ... Linking research to urban planning at the ICLEI World Congress 2018.

Full-Scale Evaluation of DuraDeck (registered trademark) and MegaDeck (trademark) Matting Systems

Science.gov (United States)

2013-07-01

plates studded with threaded bolts were placed ERDC/GSL TR-13-27 10 underneath two pre-drilled corners of the panel. The plates were positioned so...metal plates studded with threaded ERDC/GSL TR-13-27 4 Figure 1. DuraDeck® mat panel, top surface. Figure 2. DuraDeck® mat panel, bottom surface...ERDC/GSL TR-13-27 5 bolts , as shown in Figure 3, underneath the mat corners and then installing special connector nuts from the top surface

42 CFR 86.14 - Evaluation and grant award.

Science.gov (United States)

2010-10-01

... HEALTH RESEARCH AND RELATED ACTIVITIES GRANTS FOR EDUCATION PROGRAMS IN OCCUPATIONAL SAFETY AND HEALTH... effectiveness in training in these or related areas as indicated, among other things, by the placement of its... equipment, facilities, and funds, available for the project; (7) The current and potential availability of...

Dioecious Clusia nemorosa achieves pollination by combining specialized and generalized floral rewards

Czech Academy of Sciences Publication Activity Database

Vlasáková, Blanka; Jarau, S.

2011-01-01

Roč. 212, č. 8 (2011), s. 1327-1337 ISSN 1385-0237 R&D Projects: GA ČR(CZ) GD206/03/H137 Institutional research plan: CEZ:AV0Z60050516 Keywords : Clusia * inselberg * Meliponini Subject RIV: EF - Botanics Impact factor: 1.829, year: 2011

Grants: View from the Campus.

Science.gov (United States)

Mohrman, Kathryn, Ed.

Each of 13 authors, all experienced in obtaining grants, examines a separate element of the grantsgetting process. The essays include: The Characteristics of an Effective Grants Officer (Julia B. Leverenz); The Grants Office (Morton Cooper); Working with the Academic Dean (Robert C. Nordvall); Working with the Development Office (Barbara A.…

[The Continuity Between World War II and the Postwar Period: Grant Distribution by the Japan Society for the Promotion of Science and the Subsidiary Fund for Scientific Research].

Science.gov (United States)

Mizusawa, Hikari

2015-01-01

This paper analyzes the distribution of the Subsidiary Fund for Scientific Research, a predecessor to the Grant-in-Aid for Scientific Research (KAKENHI), which operated in Japan from the 1930s to 1950s. It reveals that the Japanese government maintained this wide-ranging promotion system since its establishment during the war until well into the postwar period. Previous studies insist that, at the end of the war, the Japanese government generally only funded the research that it considered immediately and practically useful. In contrast to this general perception, my analysis illustrates that both before and after the war, funding was allotted to four research areas: natural science, engineering, agriculture, and medicine. In order to illuminate this continuity, I compare the Subsidiary Fund with another research fund existing from 1933 to 1947: the Grant of the Japan Society for the Promotion of Science (JSPS). The comparison demonstrates that the JSPS received externally raised capital from the military and munitions companies. However, while this group focused upon engineering and military-related research as the war dragged on, the Subsidiary Fund has consistently entrusted scientists with the authority to decide the allocation of financial support.

Tumor-targeted polymeric nanostructured lipid carriers with precise ratiometric control over dual-drug loading for combination therapy in non-small-cell lung cancer

Directory of Open Access Journals (Sweden)

Liang Y

2017-03-01

Full Text Available Yan Liang,1 Baocheng Tian,1 Jing Zhang,1 Keke Li,1 Lele Wang,1 Jingtian Han,1,* Zimei Wu2,* 1School of Pharmacy, Binzhou Medical University, 2School of Pharmacy, Yantai University, Yantai, China *These authors contributed equally to this work Abstract: Gemcitabine (GEM and paclitaxel (PTX are effective combination anticancer agents against non-small-cell lung cancer (NSCLC. At the present time, a main challenge of combination treatment is the precision of control that will maximize the combined effects. Here, we report a novel method to load GEM (hydrophilic and PTX (hydrophobic into simplex tumor-targeted nanostructured lipid carriers (NLCs for accurate control of the ratio of the two drugs. We covalently preconjugated the dual drugs through a hydrolyzable ester linker to form drug conjugates. N-acetyl-D-glucosamine (NAG is a glucose receptor-targeting ligand. We added NAG to the formation of NAG-NLCs. In general, synthesis of poly(6-O-methacryloyl-d-galactopyranose–GEM/PTX (PMAGP-GEM/PTX conjugates was demonstrated, and NAG-NLCs were prepared using emulsification and solvent evaporation. NAG-NLCs displayed sphericity with an average diameter of 120.3±1.3 nm, a low polydispersity index of 0.233±0.04, and accurate ratiometric control over the two drugs. A cytotoxicity assay showed that the NAG-NLCs had better antitumor activity on NSCLC cells than normal cells. There was an optimal ratio of the two drugs, exhibiting the best cytotoxicity and combinatorial effects among all the formulations we tested. In comparison with both the free-drug combinations and separately nanopackaged drug conjugates, PMAGP-GEM/PTX NAG-NLCs (3:1 exhibited superior synergism. Flow cytometry and confocal laser scanning microscopy showed that NAG-NLCs exhibited higher uptake efficiency in A549 cells via glucose receptor-mediated endocytosis. This combinatorial delivery system settles problems with ratiometric coloading of hydrophilic and hydrophobic drugs for tumor

Final report, DOE/industry matching grant

International Nuclear Information System (INIS)

Kumar, Arvind S.

2003-01-01

The Department of Energy/Industry Matching Grant was used to help improve nuclear engineering and science education at the University of Missouri-Rolla. The funds helped in the areas of recruitment and retention. Funds allowed the department to give scholarships to over 100 students (names included). Funds were also used for equipment upgrade and research, including two computers with peripherals, two NaI detectors, and a thermoluminescent dosimeter

SRA Grant Writing Tutorial

Science.gov (United States)

This tutorial will help give your organization a broad but succinct analysis of what the SRA grant program is about. This self-paced tutorial is organized under two segments: Overview of Grant Program and Program Details.

An Examination of the Leadership Practices of University Presidents of Land-Grant Universities in the United States

Science.gov (United States)

Aldighrir, Wafa M.

2013-01-01

A great deal of research has been done to understand leadership styles in different organizational settings. In this study, the researcher focused on the leadership practices of university presidents of land-grant universities (LGUs) in the United States. The study examined the leadership practices of presidents of land-grant universities as…

Time-integrated thyroid dose for accidental releases from Pakistan Research Reactor-1

International Nuclear Information System (INIS)

Raza, S Shoaib; Iqbal, M; Salahuddin, A; Avila, R; Pervez, S

2004-01-01

The two-hourly time-integrated thyroid dose due to radio-iodines released to the atmosphere through the exhaust stack of Pakistan Research Reactor-1 (PARR-1), under accident conditions, has been calculated. A computer program, PAKRAD (which was developed under an IAEA research grant, PAK/RCA/8990), was used for the dose calculations. The sensitivity of the dose results to different exhaust flow rates and atmospheric stability classes was studied. The effect of assuming a constant activity concentration (as a function of time) within the containment air volume and an exponentially decreasing air concentration on the time-integrated dose was also studied for various flow rates (1000-50,000 m 3 h -1 ). The comparison indicated that the results were insensitive to the containment air exhaust rates up to or below 2000 m 3 h -1 , when the prediction with the constant activity concentration assumption was compared to an exponentially decreasing activity concentration model. The results also indicated that the plume touchdown distance increases with increasing atmospheric stability. (note)

Ulysses S. Grant and Reconstruction.

Science.gov (United States)

Wilson, David L.

1989-01-01

Discusses the role played by Ulysses S. Grant during the four years of Reconstruction before he became President of the United States. Describes the dynamics of the relationship between Grant and Andrew Johnson. Points out that Grant's attitude of service to the laws created by Congress submerged his desire to create a new South. (KO)

76 FR 17711 - Notice of Availability of Calendar Year 2012 Competitive Grant Funds

Science.gov (United States)

2011-03-30

... , or visit the grants competition Web site at http://www.grants.lsc.gov . SUPPLEMENTARY INFORMATION... Delaware DE-1, MDE Guam GU-1 Idaho ID-1, MID, NID-1 Iowa IA-3, MIA Kansas KS-1 Maine ME-1, MMX-1, NME-1...

Research in Stochastic Processes.

Science.gov (United States)

1982-10-31

Office of Scientific Research Grant AFOSR F49620 82 C 0009 Period: 1 Noveber 1981 through 31 October 1982 Title: Research in Stochastic Processes Co...STA4ATIS CAMBANIS The work briefly described here was developed in connection with problems arising from and related to the statistical comunication

FY2010 CoC Competition Grants

Data.gov (United States)

Department of Housing and Urban Development — This report displays the homeless assistance projects being awarded by HUD under the 2010 Continuum of Care (CoC) competitive grants process. Approximately $1.411...

42 CFR 59.4 - How does one apply for a family planning services grant?

Science.gov (United States)

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false How does one apply for a family planning services... GRANTS GRANTS FOR FAMILY PLANNING SERVICES Project Grants for Family Planning Services § 59.4 How does one apply for a family planning services grant? (a) Application for a grant under this subpart shall...

GRANTS FOR PH.D. STUDENTS ON VSB‐TECHNICAL UNIVERSITY OF OSTRAVA IN THE CZECH REPUBLIC

Directory of Open Access Journals (Sweden)

Pavla FOITOVÁ DERNEROVÁ

2013-07-01

Full Text Available Projects and grants are unique for development of science and research. For many people it is only source of money for their research. Particularly on universities the projects expanded. From this reason the participation of Ph.D. students in the Student Grant Competition is the best start in this field. Paper discusses in its first part how the Student Grant Competition takes its place on Technical University of Ostrava. Focuses on difficulties with submission of the application, explain process of whole project evaluation and states total amounts acquired from the Ministry of Education, Youth and Sports for Student Grand Competitions since 2010. Second part of this paper directly shows concrete project for “Research of utilization of mining waste in chosen localities.” In the paper is described subject of the research, concrete goals of project, timetable. It is stated the preliminary budget of project and actual progress in the project.

Crowd-funded micro-grants for genomics and "big data": an actionable idea connecting small (artisan) science, infrastructure science, and citizen philanthropy.

Science.gov (United States)

Özdemir, Vural; Badr, Kamal F; Dove, Edward S; Endrenyi, Laszlo; Geraci, Christy Jo; Hotez, Peter J; Milius, Djims; Neves-Pereira, Maria; Pang, Tikki; Rotimi, Charles N; Sabra, Ramzi; Sarkissian, Christineh N; Srivastava, Sanjeeva; Tims, Hesther; Zgheib, Nathalie K; Kickbusch, Ilona

2013-04-01

Biomedical science in the 21(st) century is embedded in, and draws from, a digital commons and "Big Data" created by high-throughput Omics technologies such as genomics. Classic Edisonian metaphors of science and scientists (i.e., "the lone genius" or other narrow definitions of expertise) are ill equipped to harness the vast promises of the 21(st) century digital commons. Moreover, in medicine and life sciences, experts often under-appreciate the important contributions made by citizen scholars and lead users of innovations to design innovative products and co-create new knowledge. We believe there are a large number of users waiting to be mobilized so as to engage with Big Data as citizen scientists-only if some funding were available. Yet many of these scholars may not meet the meta-criteria used to judge expertise, such as a track record in obtaining large research grants or a traditional academic curriculum vitae. This innovation research article describes a novel idea and action framework: micro-grants, each worth $1000, for genomics and Big Data. Though a relatively small amount at first glance, this far exceeds the annual income of the "bottom one billion"-the 1.4 billion people living below the extreme poverty level defined by the World Bank ($1.25/day). We describe two types of micro-grants. Type 1 micro-grants can be awarded through established funding agencies and philanthropies that create micro-granting programs to fund a broad and highly diverse array of small artisan labs and citizen scholars to connect genomics and Big Data with new models of discovery such as open user innovation. Type 2 micro-grants can be funded by existing or new science observatories and citizen think tanks through crowd-funding mechanisms described herein. Type 2 micro-grants would also facilitate global health diplomacy by co-creating crowd-funded micro-granting programs across nation-states in regions facing political and financial instability, while sharing similar disease

Competitive Grants for Digital Innovation in Latin America and the ...

International Development Research Centre (IDRC) Digital Library (Canada)

Competitive Grants for Digital Innovation in Latin America and the Caribbean - Phase II ... and funded 26 research projects developed by institutions in 13 countries. ... information and communication technologies (ICTs), and help formulate the ...

Grant management procedure for energy saving TDM-PONs

Science.gov (United States)

Alaelddin, Fuad Yousif Mohammed; Newaz, S. H. Shah; AL-Hazemi, Fawaz; Choi, Jun Kyun

2018-01-01

In order to minimize energy consumption in Time Division Multiplexing-Passive Optical Network (TDM-PON), IEEE and ITU-T have mandated sleep mode mechanism for Optical Network Units (ONUs) in the latest TDM-PON standards (e.g. IEEE P1904.1 SIEPON, ITU-T G.sup45). The sleep mode mechanism is a promising mean for maximizing energy saving in an ONU. An ONU in sleep mode flips between sleep and active state depending on the presence or absent of upstream and downstream frames. To ensure Quality of Service (QoS) of upstream frames, the recent TDM-PON standards introduced an early wake-up mechanism, in which an ONU is forced to leave the sleep state on upstream frame arrival. When the Optical Line Terminal (OLT) of a TDM-PON allows early wake-up of its connected ONUs, it allocates gratuitous grants for the sleeping ONUs along with allocating upstream grants for the ONUs in active state. Note that, the gratuitous grants control message sent periodically by the OLT on Inter-Gratuitous grant Interval (IGI) time. After leaving sleep state due to the arrival of upstream frame, the ONU uses its allocated gratuitous grant to send a control message mentioning the amount of upstream bandwidth (upstream grant) required in order to forward the remaining frames in its buffer. However, the existing early wake-up process of ONU can lead to increase the energy consumption of an ONU. It is because of the ONU wakes-up immediately from the sleep state on arrival of the upstream frame, but even so, it needs to wait for forwarding the frame until its allocated gratuitous grant period, resulting in spending energy unnecessarily. In addition, current energy saving solution for TDM-PONs do not provide a clear solution on how to manage different types of grants (e.g. listening grant, upstream transmission grant) within a Dynamic Bandwidth Allocation (DBA) polling cycle. To address this problem, we propose a state-of-art Grant Management Procedure (GMP) in order to maximize energy saving in a TDM

Final Report for U.S. DOE GRANT No. DEFG02-96ER41015 November 1, 2010 - April 30, 2013 entitled HIGH ENERGY ACCELERATOR AND COLLIDING BEAM USER GROUP at the UNIVERSITY of MARYLAND

Energy Technology Data Exchange (ETDEWEB)

Hadley, Nicholas [University of Maryland College Park; Jawahery, Abolhassan [University of Maryland College Park; Eno, Sarah C [University of Maryland College Park; Skuja, Andris [University of Maryland College Park; Baden, Andrew [University of Maryland College Park; Roberts, Douglas [University of Maryland College Park

2013-07-26

We have finished the third year of a three year grant cycle with the U.S. Department of Energy for which we were given a five month extension (U.S. D.O.E. Grant No. DEFG02-96ER41015). This document is the fi nal report for this grant and covers the period from November 1, 2010 to April 30, 2013. The Maryland program is administered as a single task with Professor Nicholas Hadley as Principal Investigator. The Maryland experimental HEP group is focused on two major research areas. We are members of the CMS experiment at the LHC at CERN working on the physics of the Energy Frontier. We are also analyzing the data from the Babar experiment at SLAC while doing design work and R&D towards a Super B experiment as part of the Intensity Frontier. We have recently joined the LHCb experiment at CERN. We concluded our activities on the D experiment at Fermilab in 2009.

Protecting Ideas: Ethical and Legal Considerations When a Grant's Principal Investigator Changes.

Science.gov (United States)

Koniaris, Leonidas G; Coombs, Mary I; Meslin, Eric M; Zimmers, Teresa A

2016-08-01

Ethical issues related the responsible conduct of research involve questions concerning the rights and obligations of investigators to propose, design, implement, and publish research. When a principal investigator (PI) transfers institutions during a grant cycle, financial and recognition issues need to be addressed to preserve all parties' obligations and best interests in a mutually beneficial way. Although grants often transfer with the PI, sometimes they do not. Maintaining a grant at an institution after the PI leaves does not negate the grantee institution's obligation to recognize the PI's original ideas, contributions, and potential rights to some forms of expression and compensation. Issues include maintaining a role for the PI in determining how to take credit for, share and publish results that involve his or her original ideas. Ascribing proper credit can become a thorny issue. This paper provides a framework for addressing situations and disagreements that may occur when a new PI continues the work after the original PI transfers. Included are suggestions for proactively developing institutional mechanisms that address such issues. Considerations include how to develop solutions that comply with the responsible conduct of research, equitably resolve claims regarding reporting of results, and avoid the possibility of plagiarism.

Research Costs Investigated: A Study Into the Budgets of Dutch Publicly Funded Drug-Related Research.

Science.gov (United States)

van Asselt, Thea; Ramaekers, Bram; Corro Ramos, Isaac; Joore, Manuela; Al, Maiwenn; Lesman-Leegte, Ivonne; Postma, Maarten; Vemer, Pepijn; Feenstra, Talitha

2018-01-01

The costs of performing research are an important input in value of information (VOI) analyses but are difficult to assess. The aim of this study was to investigate the costs of research, serving two purposes: (1) estimating research costs for use in VOI analyses; and (2) developing a costing tool to support reviewers of grant proposals in assessing whether the proposed budget is realistic. For granted study proposals from the Netherlands Organization for Health Research and Development (ZonMw), type of study, potential cost drivers, proposed budget, and general characteristics were extracted. Regression analysis was conducted in an attempt to generate a 'predicted budget' for certain combinations of cost drivers, for implementation in the costing tool. Of 133 drug-related research grant proposals, 74 were included for complete data extraction. Because an association between cost drivers and budgets was not confirmed, we could not generate a predicted budget based on regression analysis, but only historic reference budgets given certain study characteristics. The costing tool was designed accordingly, i.e. with given selection criteria the tool returns the range of budgets in comparable studies. This range can be used in VOI analysis to estimate whether the expected net benefit of sampling will be positive to decide upon the net value of future research. The absence of association between study characteristics and budgets may indicate inconsistencies in the budgeting or granting process. Nonetheless, the tool generates useful information on historical budgets, and the option to formally relate VOI to budgets. To our knowledge, this is the first attempt at creating such a tool, which can be complemented with new studies being granted, enlarging the underlying database and keeping estimates up to date.

Nuclear reactor and materials science research: Technical report, May 1, 1985-September 30, 1986

International Nuclear Information System (INIS)

1987-01-01

Throughout the 17-month period of its grant, May 1, 1985-September 30, 1986, the MIT Research Reactor (MITR-II) was operated in support of research and academic programs in the physical and life sciences and in related engineering fields. The reactor was operated 4115 hours during FY 1986 and for 6080 hours during the entire 17-month period, an average of 82 hours per week. Utilization of the reactor during that period may be classified as follows: neutron beam tube research; nuclear materials research and development; radiochemistry and trace analysis; nuclear medicine; radiation health physics; computer control of reactors; dose reduction in nuclear power reactors; reactor irradiations and services for groups outside MIT; MIT Research Reactor. Data on the above utilization for FY 1986 show that the MIT Nuclear Reactor Laboratory (NRL) engaged in joint activities with nine academic departments and interdepartmental laboratories at MIT, the Charles Stark Draper Laboratory in Cambridge, and 22 other universities and nonprofit research institutions, such as teaching hospitals

30 CFR 285.408 - May I assign my lease or grant interest?

Science.gov (United States)

2010-07-01

... RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Lease and Grant... application to MMS. The assignment application must include: (1) The MMS-assigned lease or grant number; (2) A... required financial assurance. (c) If you submit an application to assign a lease or grant, you will...

Peer Review of Grant Applications: Criteria Used and Qualitative Study of Reviewer Practices

Science.gov (United States)

Abdoul, Hendy; Perrey, Christophe; Amiel, Philippe; Tubach, Florence; Gottot, Serge; Durand-Zaleski, Isabelle; Alberti, Corinne

2012-01-01

Background Peer review of grant applications has been criticized as lacking reliability. Studies showing poor agreement among reviewers supported this possibility but usually focused on reviewers’ scores and failed to investigate reasons for disagreement. Here, our goal was to determine how reviewers rate applications, by investigating reviewer practices and grant assessment criteria. Methods and Findings We first collected and analyzed a convenience sample of French and international calls for proposals and assessment guidelines, from which we created an overall typology of assessment criteria comprising nine domains relevance to the call for proposals, usefulness, originality, innovativeness, methodology, feasibility, funding, ethical aspects, and writing of the grant application. We then performed a qualitative study of reviewer practices, particularly regarding the use of assessment criteria, among reviewers of the French Academic Hospital Research Grant Agencies (Programmes Hospitaliers de Recherche Clinique, PHRCs). Semi-structured interviews and observation sessions were conducted. Both the time spent assessing each grant application and the assessment methods varied across reviewers. The assessment criteria recommended by the PHRCs were listed by all reviewers as frequently evaluated and useful. However, use of the PHRC criteria was subjective and varied across reviewers. Some reviewers gave the same weight to each assessment criterion, whereas others considered originality to be the most important criterion (12/34), followed by methodology (10/34) and feasibility (4/34). Conceivably, this variability might adversely affect the reliability of the review process, and studies evaluating this hypothesis would be of interest. Conclusions Variability across reviewers may result in mistrust among grant applicants about the review process. Consequently, ensuring transparency is of the utmost importance. Consistency in the review process could also be improved by

Centralisation, décentralisation et accès aux services urbains : le cas de l’enlèvement des ordures ménagères à Abidjan Centralization, decentralization, access to urban public services : waste collection in Abidjan

Directory of Open Access Journals (Sweden)

Amandine Henry

2013-03-01

Full Text Available Cet article traite de l’inégalité d’accès aux services publics urbains dans les pays en développement et, plus particulièrement, de la question de l’accès au service d’enlèvement des ordures ménagères à Abidjan. Cette question est étroitement liée au mouvement de centralisation, décentralisation et recentralisation qui a affecté la gestion de ce service au cours des dernières décennies. Chaque étape de l’avancée de la Côte d’Ivoire dans le processus de décentralisation a provoqué des changements institutionnels dans la gestion des ordures ménagères à Abidjan ; tous ont eu des effets spécifiques sur l’accès de la population à ce service. Ces effets sont étudiés à l’échelle des communes et des quartiers à travers une enquête de terrain, et sont liés aux caractéristiques socio-économiques des quartiers. Une analyse comparative entre deux communes de standing opposé, ainsi que l’examen des aspects historiques de la problématique, s’attachent à identifier les facteurs-clés d’une telle inégalité d’accès au service d’enlèvement des ordures ménagères à Abidjan.This paper deals with the inequality of access to the urban public utilities in developing countries, and more accurately with the issue of the access to the waste collection in Abidjan. This question is closely linked with the centralization, decentralization and recentralization movements that affected this service management for the last decades. Each stage of the decentralization process in Ivory Coast brought institutional changes in waste collection management in Abidjan. Each of them had specific consequences on the access of people to this service. These consequences are investigated on a local scale and are linked to the socio-economic characteristics of the studied areas. Together with the focus on the historical aspects of the problematic, a comparative analysis between two districts of opposite standing attempts

Dutch research funding, gender bias, and Simpson’s paradox

NARCIS (Netherlands)

Albers, Casper J.

2015-01-01

Based on, among other criteria, three consecutive years of grant applications to the “Veni programme” of the Netherlands Organization for Scientific Research (NWO), van der Lee and Ellemers (1) conclude that these data “provide compelling evidence of gender bias in personal grant applications to

22 CFR 210.650 - Grant.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Grant. 210.650 Section 210.650 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE... to transfer a thing of value to the recipient to carry out a public purpose of support or stimulation...

15 CFR 29.650 - Grant.

Science.gov (United States)

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Grant. 29.650 Section 29.650 Commerce and Foreign Trade Office of the Secretary of Commerce GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE... Federal Government's direct benefit or use; and (b) In which substantial involvement is not expected...

Block Grants and the New Federalism: Boon or Bane.

Science.gov (United States)

Williams, Ben

1983-01-01

The new federalism is explained, and reaction to block grants in California is described. Some alternatives to current proposals and programs, effects on research in the social sciences and human services, and conclusions about the prospects for the new federalism proposals are discussed. (MSE)

An Analysis of Canadian Institute for Health Research Funding for Research on Autism Spectrum Disorder

Directory of Open Access Journals (Sweden)

R. Deonandan

2016-01-01

Full Text Available We examined patterns of Canadian Institute for Health Research (CIHR funding on autism spectrum disorder (ASD research. From 1999 to 2013, CIHR funded 190 ASD grants worth $48 million. Biomedical research received 43% of grants (46% of dollars, clinical research 27% (41%, health services 10% (7%, and population health research 8% (3%. The greatest number of grants was given in 2009, but 2003 saw the greatest amount. Funding is clustered in a handful of provinces and institutions, favouring biomedical research and disfavouring behavioural interventions, adaptation, and institutional response. Preference for biomedical research may be due to the detriment of clinical research.

Research in theoretical radiobiology and radiological physics: Final technical report, May 1, 1986-December 31, 1987

International Nuclear Information System (INIS)

Rossi, H.H.

1987-12-01

The work carried out under this Grant included continuation of experimental research in radiation biophysics that was previously initiated, as well as extensive theoretical efforts primarily devoted to the further development of the Theory of Dual Radiation Action. Documents for international and national organizations were prepared or evaluated. Attendance at a number of international and national meetings and scientific correspondence were also in part supported by this grant. 14 refs

40 CFR 40.125-1 - Limitations on duration.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Limitations on duration. 40.125-1 Section 40.125-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE RESEARCH AND DEMONSTRATION GRANTS § 40.125-1 Limitations on duration. (a) [Reserved] (b) No...

Welfare financing : Grant allocation and efficiency

NARCIS (Netherlands)

Toolsema-Veldman, Linda; Allers, M.A.

2012-01-01

Welfare is often administered locally, but financed through grants from the central government. This raises the question how the central government can prevent local governments from spending more than necessary. Block grants are more efficient than matching grants, because the latter reduce the

Natural Object Categorization.

Science.gov (United States)

1987-11-01

gram (MEG)) Igr-pen IR)) (gr-rif CS))£ (gr-kan (R)) (dole ( porn )) - (esculin (po*n)) (bile (a)) (gic (18)) :(Saaicln (nag poxn)) :( arab (Poo...glc (Is)) (fsailn (nlaq pas)) ;( arab (pas)) (rham ( porn )) (nfl (1 2 3 4)) (nf2 C1 2 3 4))))) 206% % %V *A A 0 (dofvar 3ACTZ3Z&-YX-S13C (make-instance...qr-rif MS) (qr-kan (R)) (dole (nag)) (exculin (pasn)) (bile (a)) (gIG (12)) ;(sailcin rnag)) ŕ ( arab Ineg)) (rham (nag)) (nfl (1 23 4)))) (defvar M

Inversion of allosteric effect of arginine on N-acetylglutamate synthase, a molecular marker for evolution of tetrapods

Directory of Open Access Journals (Sweden)

Cabrera-Luque Juan

2008-09-01

Full Text Available Abstract Background The efficient conversion of ammonia, a potent neurotoxin, into non-toxic metabolites was an essential adaptation that allowed animals to move from the aquatic to terrestrial biosphere. The urea cycle converts ammonia into urea in mammals, amphibians, turtles, snails, worms and many aquatic animals and requires N-acetylglutamate (NAG, an essential allosteric activator of carbamylphosphate synthetase I (CPSI in mammals and amphibians, and carbamylphosphate synthetase III (CPSIII in fish and invertebrates. NAG-dependent CPSI and CPSIII catalyze the formation of carbamylphosphate in the first and rate limiting step of ureagenesis. NAG is produced enzymatically by N-acetylglutamate synthase (NAGS, which is also found in bacteria and plants as the first enzyme of arginine biosynthesis. Arginine is an allosteric inhibitor of microbial and plant NAGS, and allosteric activator of mammalian NAGS. Results Information from mutagenesis studies of E. coli and P. aeruginosa NAGS was combined with structural information from the related bacterial N-acetylglutamate kinases to identify four residues in mammalian NAGS that interact with arginine. Substitutions of these four residues were engineered in mouse NAGS and into the vertebrate-like N-acetylglutamate synthase-kinase (NAGS-K of Xanthomonas campestris, which is inhibited by arginine. All mutations resulted in arginine losing the ability to activate mouse NAGS, and inhibit X. campestris NAGS-K. To examine at what point in evolution inversion of arginine effect on NAGS occur, we cloned NAGS from fish and frogs and examined the arginine response of their corresponding proteins. Fish NAGS were partially inhibited by arginine and frog NAGS were activated by arginine. Conclusion Difference in arginine effect on bacterial and mammalian NAGS most likely stems from the difference in the type of conformational change triggered by arginine binding to these proteins. The change from arginine

Crowd-Funded Micro-Grants for Genomics and “Big Data”: An Actionable Idea Connecting Small (Artisan) Science, Infrastructure Science, and Citizen Philanthropy

Science.gov (United States)

Badr, Kamal F.; Dove, Edward S.; Endrenyi, Laszlo; Geraci, Christy Jo; Hotez, Peter J.; Milius, Djims; Neves-Pereira, Maria; Pang, Tikki; Rotimi, Charles N.; Sabra, Ramzi; Sarkissian, Christineh N.; Srivastava, Sanjeeva; Tims, Hesther; Zgheib, Nathalie K.; Kickbusch, Ilona

2013-01-01

Abstract Biomedical science in the 21st century is embedded in, and draws from, a digital commons and “Big Data” created by high-throughput Omics technologies such as genomics. Classic Edisonian metaphors of science and scientists (i.e., “the lone genius” or other narrow definitions of expertise) are ill equipped to harness the vast promises of the 21st century digital commons. Moreover, in medicine and life sciences, experts often under-appreciate the important contributions made by citizen scholars and lead users of innovations to design innovative products and co-create new knowledge. We believe there are a large number of users waiting to be mobilized so as to engage with Big Data as citizen scientists—only if some funding were available. Yet many of these scholars may not meet the meta-criteria used to judge expertise, such as a track record in obtaining large research grants or a traditional academic curriculum vitae. This innovation research article describes a novel idea and action framework: micro-grants, each worth $1000, for genomics and Big Data. Though a relatively small amount at first glance, this far exceeds the annual income of the “bottom one billion”—the 1.4 billion people living below the extreme poverty level defined by the World Bank ($1.25/day). We describe two types of micro-grants. Type 1 micro-grants can be awarded through established funding agencies and philanthropies that create micro-granting programs to fund a broad and highly diverse array of small artisan labs and citizen scholars to connect genomics and Big Data with new models of discovery such as open user innovation. Type 2 micro-grants can be funded by existing or new science observatories and citizen think tanks through crowd-funding mechanisms described herein. Type 2 micro-grants would also facilitate global health diplomacy by co-creating crowd-funded micro-granting programs across nation-states in regions facing political and financial instability, while

The grant game as training ground for tractability?

DEFF Research Database (Denmark)

Petersen, Eva Bendix

2016-01-01

The future of education research is linked to what early career researchers in Education are doing and learning to do now. This paper presents a narrative of one early career researcher who works and lives in Australia. She tells the story about how she came to research and to an academic life......, about what her doctoral work and education taught her and how now, as an academic in an on-going position, she feels needs to unlearn many of those values and practices in order to succeed particularly in the so-called ‘grant game’. The narrative format, though, is intended to invite and encourage other...

Institutional Motivation and Policy Change Associated with Land Grant Institutions' Involvement in Economic Development. ASHE Annual Meeting Paper.

Science.gov (United States)

Cote, Lawrence S.; And Others

A study investigated: (1) the degree of land grant institution involvement in economic development activity, defined in terms of 17 selected cooperative research and technology exchange activities; (2) changes in selected academic policies (patents, consulting, conflict of interest, conflict of commitment, and extra compensation); and (3) the…

41 CFR 105-74.650 - Grant.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Grant. 105-74.650 Section 105-74.650 Public Contracts and Property Management Federal Property Management Regulations System...-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74.650 Grant. Grant...

44 CFR 204.25 - FEMA-State agreement for fire management assistance grant program.

Science.gov (United States)

2010-10-01

... GRANT PROGRAM Declaration Process § 204.25 FEMA-State agreement for fire management assistance grant... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false FEMA-State agreement for fire management assistance grant program. 204.25 Section 204.25 Emergency Management and Assistance FEDERAL...

22 CFR 63.5 - Grants to foreign participants to study.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Grants to foreign participants to study. 63.5 Section 63.5 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES PAYMENTS TO AND ON BEHALF OF PARTICIPANTS IN THE INTERNATIONAL EDUCATIONAL AND CULTURAL EXCHANGE PROGRAM § 63.5 Grants to...

42 CFR 86.10 - Nature and purpose of training grants.

Science.gov (United States)

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Nature and purpose of training grants. 86.10 Section 86.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL... AND HEALTH Occupational Safety and Health Training Grants § 86.10 Nature and purpose of training...

77 FR 11778 - Reform of Federal Policies Relating to Grants and Cooperative Agreements; Cost Principles and...

Science.gov (United States)

2012-02-28

... and II Reform of Federal Policies Relating to Grants and Cooperative Agreements; Cost Principles and... available on OMB's Web site at http://www.whitehouse.gov/omb/circulars_default/ . The Cost Principles for... E (Principles for Determining Costs Applicable to Research and Development Under Grants and...

7 CFR 1948.95 - Grant monitoring.

Science.gov (United States)

2010-01-01

... 7 Agriculture 13 2010-01-01 2009-01-01 true Grant monitoring. 1948.95 Section 1948.95 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... § 1948.95 Grant monitoring. Each grant will be monitored by FmHA or its successor agency under Public Law...

ENVIRONMENTAL PROTECTION: Information on EPA Project Grants and Use of Waiver Authority

National Research Council Canada - National Science Library

2001-01-01

...) awards grants to both public and private entities such as nonprofit organizations, colleges, and universities for a variety of environmental projects including research, education, and public outreach...

[Start-up grants for young scientists in German medical universities : Can the clinical scientist be saved?

Science.gov (United States)

Pabst, R; Linke, P B; Neudeck, N B A; Schmiel, M; Ernst, S B

2016-12-01

German medical faculties currently have severe financial problems. There is the conflict between financing teaching medical students, inpatient and outpatient costs and supporting basic and applied research. Young postdocs can apply for a grant to start research projects to establish techniques on publishing data as a basis for applying for grants from the German Research Foundation or foundations with a critical review system. Successful applicants from the years 1998-2011 were asked to answer a questionnaire. The annual number of applications ranged from 28 to 96 per year. Within the first period of our analysis ranging from 1998 to 2004, a mean number of 69.5 % ± 14.0 % of submitted grant applications were approved annually in comparison to an average approval of 30.9 % ± 11 % in the years 2006-2001. In total 353 projects were funded with a mean amount of money for a project of approximately 18,640 EUR. The mean amount of external grant money following the start-up period was 7.2 times the money initially spent. That is an excellent return of investment. There were no differences between applicants from the department of surgery or department of internal medicine. In the meantime, 56 % of men and 42 % of women have achieved the academic degree university lecturer (privatdozent). Furthermore, 71 % of the participants evaluated this start-up research as supportive for their postdoctoral qualification (habilitation). The program for initial investment for young postdocs by internal start-up grants is overall successful.

Using a student-faculty collaborative learning model to teach grant development in graduate nursing education.

Science.gov (United States)

Falk, Nancy L; Phillips, Kathleen M; Hymer, Regina; Acquaviva, Kimberly D; Schumann, Mary Jean

2014-05-01

Graduate nurses are employed in clinical, research, educational, and policy roles. As leaders, they are expected to develop and sustain projects that support translating research to practice and policy. Funding to support initiatives is tight and requires innovative solutions to cover salaries, benefits, equipment purchases, and other program expenses. In an effort to teach grant writing while developing skilled leaders who are effective and competitive in securing funds, the George Washington University School of Nursing offers a graduate-level grant writing course. In the summer of 2011, a collaborative learning model was developed within the course. The joint approach was foundational to securing an Agency for Healthcare Research and Quality grant to support development and implementation of a patient engagement project by the Nursing Alliance for Quality Care. This article describes the project and offers hints for those seeking to develop a collaborative educational experience that affords new leadership skills for RNs from all backgrounds. Copyright 2014, SLACK Incorporated.

Export support of renewable energy industries, grant number 1, deliverable number 3. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-01-14

The United States Export Council for Renewable Energy (US/ECRE), a consortium of six industry associations, promotes the interests of the renewable energy and energy efficiency member companies which provide goods and services in biomass, geothermal, hydropower, passive solar, photovoltaics, solar thermal, wind, wood energy, and energy efficiency technologies. US/ECRE`s mission is to catalyze export markets for renewable energy and energy efficiency technologies worldwide. Under this grant, US/ECRE has conducted a number of in-house activities, as well as to manage activities by member trade associations, affiliate organizations and non-member contractors and consultants. The purpose of this document is to report on grant coordination and effectiveness.

Polyvinylidene Fluoride Micropore Membranes as Solid-Phase Extraction Disk for Preconcentration of Nanoparticulate Silver in Environmental Waters.

Science.gov (United States)

Zhou, Xiao-Xia; Lai, Yu-Jian; Liu, Rui; Li, Sha-Sha; Xu, Jing-Wen; Liu, Jing-Fu

2017-12-05

Efficient separation and preconcentration of trace nanoparticulate silver (NAg) from large-volume environmental waters is a prerequisite for reliable analysis and therefore understanding the environmental processes of silver nanoparticles (AgNPs). Herein, we report the novel use of polyvinylidene fluoride (PVDF) filter membrane for disk-based solid phase extraction (SPE) of NAg in 1 L of water samples with the disk-based SPE system, which consists of a syringe pump and a syringe filter holder to embed the filter membrane. While the PVDF membrane can selectively adsorb NAg in the presence of Ag + , aqueous solution of 2% (m/v) FL-70 is found to efficiently elute NAg. Analysis of NAg is performed following optimization of filter membrane and elution conditions with an enrichment factor of 1000. Additionally, transmission electron microscopy (TEM), UV-vis spectroscopy, and size-exclusion chromatography coupled with ICP-MS (SEC-ICP-MS) analysis showed that the extraction gives rise to no change in NAg size or shape, making this method attractive for practical applications. Furthermore, feasibility of the protocol is verified by applying it to extract NAg in four real waters with recoveries of 62.2-80.2% at 0.056-0.58 μg/L spiked levels. This work will facilitate robust studies of trace NAg transformation and their hazard assessments in the environment.

Final Report DOE Grant# DE-FG02-98ER62592: Second Cancers, Tumor p53, and Archaea Research

Energy Technology Data Exchange (ETDEWEB)

Lesko, Samuel M. [Northeast Regional Cancer Institute, Scranton, PA (United States)

2006-01-14

The Northeast Regional Cancer Institute conducted cancer surveillance in Northeast Pennsylvania using data from the institute's population-based regional cancer registry and the Pennsylvania Cancer Registry. The results of this surveillance have been used to set priorities for research and outreach activities at the Cancer Institute and selected results have been reported to medical professionals at member hospitals and in the community. One consistent observation of this surveillance was that colorectal cancer was unusually common in Northeast Pennsylvania; incidence was approximately 25% higher than the rate published for NCI's Surveillance Epidemiology and End Results (SEER) Program. In addition, death rates form colorectal cancer in several counties in this region were above the 90Th percentile for colorectal cancer mortality in the United States. As a result of these observations, several activities have been developed to increase awareness of colorectal cancer and the value of screening for this cancer in both the lay and medical communities. Funding from this grant also provided support for a population-based study of cancer risk factors, screening practices, and related behaviors. This project continues beyond the termination of the present grant with funding from other sources. This project gathers data from a representative sample of adults residing in a six county area of Northeast Pennsylvania. Analyses conducted to date of the established risk factors for colorectal cancer have not revealed an explanation for the high incidence of this cancer in this population.

Shock tube measurements of the rate constants for seven large alkanes+OH

KAUST Repository

Badra, Jihad; Elwardani, Ahmed Elsaid; Farooq, Aamir

2015-01-01

subscripts indicate the number of carbon atoms bonded to the next-nearest-neighbor carbon): S20=1.58×10-11exp(-1550K/T)cm3molecule-1s-1(887-1327K)S30=2.37×10-11exp(-1850K/T)cm3molecule-1s-1(887-1327K)S21=4.5×10-12exp(-793.7K/T)cm3molecule-1s-1(833-1440K)T100=2

42 CFR 52.6 - Grant awards.

Science.gov (United States)

2010-10-01

... grant to those applicants whose approved projects will in the Secretary's judgment best promote the..., the grant will initially be for one year and subsequent continuation awards will also be for one year... application nor the award of any grant commits or obligates the United States in any way to make any...

Prior publication productivity, grant percentile ranking, and topic-normalized citation impact of NHLBI cardiovascular R01 grants.

Science.gov (United States)

Kaltman, Jonathan R; Evans, Frank J; Danthi, Narasimhan S; Wu, Colin O; DiMichele, Donna M; Lauer, Michael S

2014-09-12

We previously demonstrated absence of association between peer-review-derived percentile ranking and raw citation impact in a large cohort of National Heart, Lung, and Blood Institute cardiovascular R01 grants, but we did not consider pregrant investigator publication productivity. We also did not normalize citation counts for scientific field, type of article, and year of publication. To determine whether measures of investigator prior productivity predict a grant's subsequent scientific impact as measured by normalized citation metrics. We identified 1492 investigator-initiated de novo National Heart, Lung, and Blood Institute R01 grant applications funded between 2001 and 2008 and linked the publications from these grants to their InCites (Thompson Reuters) citation record. InCites provides a normalized citation count for each publication stratifying by year of publication, type of publication, and field of science. The coprimary end points for this analysis were the normalized citation impact per million dollars allocated and the number of publications per grant that has normalized citation rate in the top decile per million dollars allocated (top 10% articles). Prior productivity measures included the number of National Heart, Lung, and Blood Institute-supported publications each principal investigator published in the 5 years before grant review and the corresponding prior normalized citation impact score. After accounting for potential confounders, there was no association between peer-review percentile ranking and bibliometric end points (all adjusted P>0.5). However, prior productivity was predictive (Pcitation counts, we confirmed a lack of association between peer-review grant percentile ranking and grant citation impact. However, prior investigator publication productivity was predictive of grant-specific citation impact. © 2014 American Heart Association, Inc.

7 CFR 4280.110 - Grant funding.

Science.gov (United States)

2010-01-01

... renewable energy system or energy efficiency improvement. (1) Post-application purchase and installation of... UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE LOANS AND GRANTS Renewable Energy Systems and Energy Efficiency...-party equity contributions are acceptable for renewable energy system projects, including those that are...

Role of Crk Adaptor Proteins in Cellular Migration and Invasion in Human Breast Cancer

Science.gov (United States)

2008-03-01

Ali, S.M., Harvey , H.A., Lipton, A. (2003). Clin Orthop Relat Res. 415 (Suppl): S132-7. 1 2 1 2 sh C rk p Su p er MDA-231TR A B C D...research 2005;14(6):919-40. 27. Weinstein EJ, Leder P. The extracellular region of heregulin is sufficient to promote mammary gland proliferation and

In situ response of Nostoc commune s.l. colonies to desiccation in Central Svalbard, Norwegian High Arctic

Czech Academy of Sciences Publication Activity Database

Kvíderová, Jana; Elster, Josef; Šimek, Miloslav

2011-01-01

Roč. 11, č. 1 (2011), s. 87-97 ISSN 1802-5439 R&D Projects: GA MŠk ME 934; GA MŠk LA341; GA MŠk LC06066; GA AV ČR IAA600660605 Institutional research plan: CEZ:AV0Z60050516; CEZ:AV0Z60660521 Keywords : desiccation * cyanobacteria * Arctic Subject RIV: EF - Botanics Impact factor: 1.327, year: 2011

13 CFR 313.7 - Implementation grants for Impacted Communities.

Science.gov (United States)

2010-01-01

..., construction, rehabilitation and equipping of facilities; (2) Market or industry research and analysis; (3... improving the delivery of business services, or feasibility studies; (4) Public services; (5) Training; and... section 278 of the Trade Act or a Sector Partnership Grant under section 279A of the Trade Act while the...

Scientific-Technical and Business Careers Training Grant

Science.gov (United States)

Conway, Mary P.

2001-01-01

The 1996 renewal of the NGT2-1001 grant included three objectives and expected outcomes. The information highlights the results and progress to address the grant objectives and outcomes for the time period of July 1, 2000 through June 30, 2001. Objective Number One indicated that the internship staff would annually recruit and place at least 90 community college students in internship positions related to their college majors. Internship enrollments for the summer, fall, winter and spring quarters of 2000-2001 show an average enrollment of 121 students per quarter. This number includes (13) interns sponsored by Ames contractors.

Innovative Practice in Advancement of Academic Nurse Educator Careers: Developing Scholarship From Program Grants.

Science.gov (United States)

Eddy, Linda L; Hoeksel, Renee; Fitzgerald, Cindy; Doutrich, Dawn

We describe an innovative practice in advancing careers of academic nurse educators: demonstrating scholarly productivity from program grants. Scholarly productivity is often narrowly defined, especially in research-intensive institutions. The expectation may be a career trajectory based on the traditional scholarship of discovery. However, nurse educators, especially at the associate and full professor ranks, are often involved in leadership activities that include writing and managing program grants. We encourage the academy to value and support the development of program grants that include significant scholarly components, and we offer exemplars of associate and full professor scholarship derived from these projects.

Granting silence to avoid wireless collisions

KAUST Repository

Choi, Jung Il

2010-10-01

We describe grant-to-send, a novel collision avoidance algorithm for wireless mesh networks. Rather than announce packets it intends to send, a node using grant-to-send announces packets it expects to hear others send. We present evidence that inverting collision avoidance in this way greatly improves wireless mesh performance. Evaluating four protocols from 802.11 meshes and 802.15.4 sensor networks, we find that grant-to-send matches or outperforms CSMA and RTS/CTS in all cases. For example, in a 4-hop UDP flow, grantto- send can achieve 96% of the theoretical maximum throughput while maintaining a 99.9% packet delivery ratio. Grant-tosend is also general enough to replace protocol-specific collision avoidance mechanisms common to sensor network protocols. Grant-to-send is simple. For example, incorporating it into 802.11 requires only 11 lines of driver code and no hardware changes. Furthermore, as it reuses existing 802.11 mechanisms, grant-to-send inter-operates with current networks and can be incrementally deployed. © 2010 IEEE.

Granting silence to avoid wireless collisions

KAUST Repository

Choi, Jung Il; Jain, Mayank; Kazandjieva, Maria A.; Levis, Philip

2010-01-01

We describe grant-to-send, a novel collision avoidance algorithm for wireless mesh networks. Rather than announce packets it intends to send, a node using grant-to-send announces packets it expects to hear others send. We present evidence that inverting collision avoidance in this way greatly improves wireless mesh performance. Evaluating four protocols from 802.11 meshes and 802.15.4 sensor networks, we find that grant-to-send matches or outperforms CSMA and RTS/CTS in all cases. For example, in a 4-hop UDP flow, grantto- send can achieve 96% of the theoretical maximum throughput while maintaining a 99.9% packet delivery ratio. Grant-tosend is also general enough to replace protocol-specific collision avoidance mechanisms common to sensor network protocols. Grant-to-send is simple. For example, incorporating it into 802.11 requires only 11 lines of driver code and no hardware changes. Furthermore, as it reuses existing 802.11 mechanisms, grant-to-send inter-operates with current networks and can be incrementally deployed. © 2010 IEEE.

Tumor-targeted polymeric nanostructured lipid carriers with precise ratiometric control over dual-drug loading for combination therapy in non-small-cell lung cancer.

Science.gov (United States)

Liang, Yan; Tian, Baocheng; Zhang, Jing; Li, Keke; Wang, Lele; Han, Jingtian; Wu, Zimei

2017-01-01

Gemcitabine (GEM) and paclitaxel (PTX) are effective combination anticancer agents against non-small-cell lung cancer (NSCLC). At the present time, a main challenge of combination treatment is the precision of control that will maximize the combined effects. Here, we report a novel method to load GEM (hydrophilic) and PTX (hydrophobic) into simplex tumor-targeted nanostructured lipid carriers (NLCs) for accurate control of the ratio of the two drugs. We covalently preconjugated the dual drugs through a hydrolyzable ester linker to form drug conjugates. N -acetyl-d-glucosamine (NAG) is a glucose receptor-targeting ligand. We added NAG to the formation of NAG-NLCs. In general, synthesis of poly(6- O -methacryloyl-d-galactopyranose)-GEM/PTX (PMAGP-GEM/PTX) conjugates was demonstrated, and NAG-NLCs were prepared using emulsification and solvent evaporation. NAG-NLCs displayed sphericity with an average diameter of 120.3±1.3 nm, a low polydispersity index of 0.233±0.04, and accurate ratiometric control over the two drugs. A cytotoxicity assay showed that the NAG-NLCs had better antitumor activity on NSCLC cells than normal cells. There was an optimal ratio of the two drugs, exhibiting the best cytotoxicity and combinatorial effects among all the formulations we tested. In comparison with both the free-drug combinations and separately nanopackaged drug conjugates, PMAGP-GEM/PTX NAG-NLCs (3:1) exhibited superior synergism. Flow cytometry and confocal laser scanning microscopy showed that NAG-NLCs exhibited higher uptake efficiency in A549 cells via glucose receptor-mediated endocytosis. This combinatorial delivery system settles problems with ratiometric coloading of hydrophilic and hydrophobic drugs for tumor-targeted combination therapy to achieve maximal anticancer efficacy in NSCLC.

38 CFR 61.41 - Special needs grants application.

Science.gov (United States)

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Special needs grants... (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.41 Special needs grants application. (a) To apply for a special needs grant, an applicant must obtain from VA a special needs grant application...

49 CFR 110.110 - After-grant requirements.

Science.gov (United States)

2010-10-01

... PUBLIC SECTOR TRAINING AND PLANNING GRANTS § 110.110 After-grant requirements. The Associate... must submit all financial, performance, and other reports required as a condition of the grant, within...

National Science Foundation Grant Implementation: Perceptions of Teachers and Graduate Fellows in One School Regarding the Barriers and Successes

Science.gov (United States)

Pickering, Sharon Durham

The purpose of this qualitative case study was to examine the perceptions of partner teachers and graduate fellows in 1 school regarding the barriers and successes made during their participation in a National Science Foundation Grant. This study included 9 partner teachers and 7 graduate fellows who participated in the Science First! NSF GK-12 Grant. There were 16 participants in this study. This study was conducted at North Side Elementary and East Tennessee State University. Partner teachers and graduate fellows were interviewed to gain perceptions of the barriers and successes of their participation in the implementation of the Science First! grant at North Side and East Tennessee State University from 2008-2013. A list of possible participants in the study was provided from the grant leadership team. The 16 participants in the study were chosen through purposeful sampling. During data analysis, 4 themes arose as successes and 4 themes arose as barriers. The success themes were (a) relationships, (b) mutual appreciation, (c) increased academic depth, and (d) professional growth. The barriers were (a) communication, (b) time, (c) expectations, and (d) preparation. Based on the research, the following conclusions were presented. The coordination of a major NSF-GK12 grant can provide STEM support and academic rigor for a high poverty school with leadership. Positive relationships between the graduate fellows and partner teachers as well as the 2 participating institutions are critical in fostering successful grant implementation. Professional growth through the grant partnerships was obtained. The participants gained a mutual appreciation for the roles and responsibilities of each other. There are ups and downs in implementing a large grant at 1 elementary school with a university, but the rewards of the potential to influence teacher practices in STEM and student learning are great. Recommendations from the study findings may assist future grant award winners or

Successful grant proposals in science, technology, and medicine a guide to writing the narrative

CERN Document Server

Oster, Sandra

2015-01-01

There are many resources on grant writing in science, technology and medicine, but most do not provide the practical advice needed to write the narratives of grant proposals. Designed to help novice and experienced investigators write compelling narratives and acquire research funding, this is a detailed guide to the content, organisation, layout, phrasing, and scientific argumentation of narratives. The authors draw on more than twenty years of research and analysis of grant proposals, having worked extensively with investigators at different levels, from pre-doctoral students to senior scientists. They have used this experience to design a framework for scientific writing that you can apply directly to narratives. The guidelines and advice offered are applicable across many funding agencies, including the NIH and NSF. Featuring many real-life examples, the book covers a range of topics, from organisational alternatives to best practices in grammar and editing, overview visuals, and working with contributors...

GEF small grants programme - overview

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-12-01

This paper describes the GEF small grants program which seeks to enhance the role of households and communities in conserving global biodiversity, mitigating global climate change, and protecting international waters. Grants up to $50k have been granted for projects in 33 countries, with plans for 12 other countries. The author describes the framework that the program works under, and the methodology followed in developing and planning projects. The approach to climate change concerns is to emphasize the development of non-carbon energy development activities to provide energy sources and economic development.

Research Institute for Technical Careers

Science.gov (United States)

Glenn, Ronald L.

1996-01-01

The NASA research grant to Wilberforce University enabled us to establish the Research Institute for Technical Careers (RITC) in order to improve the teaching of science and engineering at Wilberforce. The major components of the research grant are infrastructure development, establishment of the Wilberforce Intensive Summer Experience (WISE), and Joint Research Collaborations with NASA Scientists. (A) Infrastructure Development. The NASA grant has enabled us to improve the standard of our chemistry laboratory and establish the electronics, design, and robotics laboratories. These laboratories have significantly improved the level of instruction at Wilberforce University. (B) Wilberforce Intensive Summer Experience (WISE). The WISE program is a science and engineering bridge program for prefreshman students. It is an intensive academic experience designed to strengthen students' knowledge in mathematics, science, engineering, computing skills, and writing. (C) Joint Collaboration. Another feature of the grant is research collaborations between NASA Scientists and Wilberforce University Scientists. These collaborations have enabled our faculty and students to conduct research at NASA Lewis during the summer and publish research findings in various journals and scientific proceedings.

7 CFR 1290.8 - Grant agreements.

Science.gov (United States)

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Grant agreements. 1290.8 Section 1290.8 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... minimum the following: (1) The projects in the approved State plan. (2) Total amount of Federal financial...

7 CFR 1291.8 - Grant agreements.

Science.gov (United States)

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Grant agreements. 1291.8 Section 1291.8 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... minimum the following: (1) The projects in the approved State plan. (2) Total amount of Federal financial...

USEPA Grants

Data.gov (United States)

U.S. Environmental Protection Agency — This is a provisional dataset that contains point locations for all grants given out by the USEPA going back to the 1960s through today. There are many limitations...

42 CFR 59.3 - Who is eligible to apply for a family planning services grant?

Science.gov (United States)

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Who is eligible to apply for a family planning... SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Project Grants for Family Planning Services § 59.3 Who is eligible to apply for a family planning services grant? Any public or nonprofit private entity in...

76 FR 40677 - Notice of Intent To Grant Exclusive License

Science.gov (United States)

2011-07-11

... Research Service, intends to grant to P & M Plastics, Inc. of Mountainair, New Mexico, an exclusive license..., 2011. ADDRESSES: Send comments to: USDA, ARS, Office of Technology Transfer, 5601 Sunnyside Avenue, Rm... of Technology Transfer at the Beltsville address given above; telephone: 301-504-5989. SUPPLEMENTARY...

76 FR 38108 - Notice of Intent to Grant Exclusive License

Science.gov (United States)

2011-06-29

... Research Service, intends to grant to P & M Signs, Inc. of Mountainair, New Mexico, an exclusive license to... July 29, 2011. ADDRESSES: Send comments to: USDA, ARS, Office of Technology Transfer, 5601 Sunnyside... Office of Technology Transfer at the Beltsville address given above; telephone: 301-504-5989...

8 CFR 1209.2 - Adjustment of status of alien granted asylum.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Adjustment of status of alien granted asylum. 1209.2 Section 1209.2 Aliens and Nationality EXECUTIVE OFFICE FOR IMMIGRATION REVIEW, DEPARTMENT OF JUSTICE IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS OF REFUGEES AND ALIENS GRANTED ASYLUM § 1209...

Synthesis and characterization of nanosilver-silicone hydrogel composites for inhibition of bacteria growth.

Science.gov (United States)

Helaly, F M; El-Sawy, S M; Hashem, A I; Khattab, A A; Mourad, R M

2017-02-01

Nanosilver-silicone hydrogel (NAgSiH) composites for contact lenses were synthesized to asses the antimicrobial effects. Silicone hydrogel (SiH) films were synthesized followed by impregnation in silver nitrate solutions (10, 20, 30, 40, 60, 80ppm) and in-situ chemical reduction of silver ions using sodium borohydride (NaBH 4 ). The silver nano particles (AgNPS) were identified by UV-vis absorption spectroscopy, Energy-dispersive X-ray spectroscopy (EDX) mapping and EDX spectrum. Physico-mechanical and chemical properties of NAgSIH films were studied. The antimicrobial effect of the hydrogels against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus was evaluated. The numbers of viable bacterial cells on NAgSiH surface or in solution compared to control SiH were examined. The NAgSiH films were successfully synthesized. FTIR results indicated that AgNPS had no effect on the bulk structure of the prepared SiH films. From TGA analysis, NAgSiH(R80) and SiH(R0) films had the same maximum decomposition temperature (404°C). UV-vis absorption spectroscopy and EDX mapping and spectrum emphasized that AgNPS were in spherical shape. The maximum absorption wavelength of NAgSiH films were around 400nm. The light transmittance decreased as the concentration of AgNPS increased, but still greater than 90% at wavelength around 555nm. The Young's modulus increased gradually from 1.06MPa of SiH(R0) to highest value 1.38MPa of NAgSiH(R80). AgNPS incorporated into SiH films reduced the bacterial cell growth and prevented colonization. Groups NAgSiH(R60,R80) demonstrated an excellent reduction in bacterial viability in solution and on the SiH surface. NAgSiH composites were successfully synthesized and possessed an excellent antimicrobial effects. Copyright © 2016 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

48 CFR 31.205-48 - Research and development costs.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Research and development... Organizations 31.205-48 Research and development costs. Research and development, as used in this subsection... grant for research and development effort, the excess is unallowable under any other Government contract...

7 CFR 3021.650 - Grant.

Science.gov (United States)

2010-01-01

... Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 3021.650 Grant. Grant means an award of financial assistance that, consistent with 31 U.S.C. 6304, is used to...

8 CFR 209.2 - Adjustment of status of alien granted asylum.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Adjustment of status of alien granted asylum. 209.2 Section 209.2 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS OF REFUGEES AND ALIENS GRANTED ASYLUM § 209.2 Adjustment of status of alien...

7 CFR 3550.102 - Grant and loan purposes.

Science.gov (United States)

2010-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF... Waste Disposal Grants § 3550.102 Grant and loan purposes. (a) Grant funds. Grant funds may be used only... repair or remodel dwellings to make them accessible and useable for household members with disabilities...

Science Granting Councils Initiative: Research uptake | CRDI ...

International Development Research Centre (IDRC) Digital Library (Canada)

The initiative's activities include training, regional exchanges and forums, online training, on-site coaching, and collaborative research. The initiative was developed jointly by IDRC, the United Kingdom's Department for International Development, and South Africa's National Research Foundation. Its ultimate goal is ...

7 CFR 3400.4 - How to apply for a grant.

Science.gov (United States)

2010-01-01

...) Format for research grant proposals. Unless otherwise stated in the specific program solicitation, the... necessarily be limited to: (i) A description of the proposed investigations and/or experiments in the sequence...; (iii) Kinds of results expected; (iv) Means by which data will be analyzed or interpreted; (v) Pitfalls...

78 FR 47009 - Notice of Intent to grant exclusive license

Science.gov (United States)

2013-08-02

... gives notice of its intent to grant an exclusive license in the United States to practice the invention... of Chief Counsel, NASA Langley Research Center, MS 30, Hampton, VA 23681, (757) 864-7686 (phone...-9190. Information about other NASA inventions available for licensing can be found online at http...

Mechanism of Action of Secreted Newt Anterior Gradient Protein.

Directory of Open Access Journals (Sweden)

Kathrin S Grassme

Full Text Available Anterior gradient (AG proteins have a thioredoxin fold and are targeted to the secretory pathway where they may act in the ER, as well as after secretion into the extracellular space. A newt member of the family (nAG was previously identified as interacting with the GPI-anchored salamander-specific three-finger protein called Prod1. Expression of nAG has been implicated in the nerve dependence of limb regeneration in salamanders, and nAG acted as a growth factor for cultured newt limb blastemal (progenitor cells, but the mechanism of action was not understood. Here we show that addition of a peptide antibody to Prod1 specifically inhibit the proliferation of blastema cells, suggesting that Prod1 acts as a cell surface receptor for secreted nAG, leading to S phase entry. Mutation of the single cysteine residue in the canonical active site of nAG to alanine or serine leads to protein degradation, but addition of residues at the C terminus stabilises the secreted protein. The mutation of the cysteine residue led to no detectable activity on S phase entry in cultured newt limb blastemal cells. In addition, our phylogenetic analyses have identified a new Caudata AG protein called AG4. A comparison of the AG proteins in a cell culture assay indicates that nAG secretion is significantly higher than AGR2 or AG4, suggesting that this property may vary in different members of the family.

75 FR 14596 - Family Violence Prevention and Services/Grants for Domestic Violence Shelters/Grants to Native...

Science.gov (United States)

2010-03-26

...This announcement governs the proposed award of formula grants under the Family Violence Prevention and Services Act (FVPSA) to Native American Tribes (including Alaska Native Villages) and Tribal organizations. The purpose of these grants is to assist Tribes in establishing, maintaining, and expanding programs and projects to prevent family violence and to provide immediate shelter and related assistance for victims of family violence and their dependents (42 U.S.C. 10401). This announcement sets forth the application requirements, the application process, and other administrative and fiscal requirements for grants in Fiscal Year (FY) 2010. Grantees are to be mindful that although the expenditure period for grants is a two-year period, an application is required every year to provide continuity in the provision of services. (See Section II. Award Information, Expenditure Periods.)

The Principal's Guide to Grant Success.

Science.gov (United States)

Bauer, David G.

This book provides principals of public and private elementary and middle schools with a step-by-step approach for developing a system that empowers faculty, staff, and the school community in attracting grant funds. Following the introduction, chapter 1 discusses the principal's role in supporting grantseeking. Chapter 2 describes how to…

Wavelength Measurements of Ni L-shell Lines between 9 and 15 A

Science.gov (United States)

Gu, Ming F.; Beiersdorfer, P.; Brown, G. V.; Chen, H.; Thorn, D. B.; Kahn, S. M.

2006-09-01

We present accurate wavelength measurements of nikel L-shell X-ray lines resulting from Δ n ≥ 1 transitions (mostly, 2 - 3 transitions) between 9 and 15 Å. We have used the electron beam ion trap, SuperEBIT, at the Lawrence Livermore National Laboratory and a flat field grating spectrometer to record the spectra. Most significant emission lines of Ni XIX -- XXVI in our spectral coverage are identified. The resulting data set provides valuable input in the analyses of high resolution X-ray spectra of stellar coronae sources, including the Sun. This work was performed under the auspices of U.S. DOE contract No. W-7405-Eng-48, and supported by NASA APRA Grant NAG5-5419.

76 FR 72978 - Premier Trim, LLC, Spectrum Trim, LLC and Grant Products International, Inc. D/B/A Spectrum Grant...

Science.gov (United States)

2011-11-28

..., Spectrum Trim, LLC and Grant Products International, Inc. D/B/A Spectrum Grant De Mexico Including Workers Whose Unemployment Insurance (UI) Wages Are Paid Through Grant Products International, Inc... Brownsville, TX; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance In...

University Reactor Instrumentation grant program. Final report, September 7, 1990--August 31, 1995

International Nuclear Information System (INIS)

Talnagi, J.W.

1998-01-01

The Ohio State University Nuclear Reactor Laboratory (OSU NRL) participated in the Department of Energy (DOE) grant program commonly denoted as the University Reactor Instrumentation (URI) program from the period September 1990 through August 1995, after which funding was terminated on a programmatic basis by DOE. This program provided funding support for acquisition of capital equipment targeted for facility upgrades and improvements, including modernizing reactor systems and instrumentation, improvements in research and instructional capabilities, and infrastructure enhancements. The staff of the OSU NRL submitted five grant applications during this period, all of which were funded either partially or in their entirety. This report will provide an overview of the activities carried out under these grants and assess their impact on the OSU NRL facilities

34 CFR 75.232 - The cost analysis; basis for grant amount.

Science.gov (United States)

2010-07-01

... Secretary sets the amount of a new grant, the Secretary does a cost analysis of the project. The Secretary... objectives of the project with reasonable efficiency and economy under the budget in the application... 34 Education 1 2010-07-01 2010-07-01 false The cost analysis; basis for grant amount. 75.232...

75 FR 76952 - Grant of Authority for Subzone Status; Lam Research Corporation (Wafer Fabrication Equipment...

Science.gov (United States)

2010-12-10

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1724] Grant of Authority for Subzone... United States, to expedite and encourage foreign commerce, and for other purposes,'' and authorizes the... benefit and is in the public interest; Whereas, the City of San Jose, California, grantee of Foreign-Trade...

FEMA Hazard Mitigation Grants Program Summary

Data.gov (United States)

Department of Homeland Security — The Hazard Mitigation Grant Program (HMGP, CFDA Number: 97.039) provides grants to States and local governments to implement long-term hazard mitigation measures...

Chemistry, Dynamics, and Radiation of Ozone Loss: Airborne Measurements of OH, HO2, NO2, ClO, BrO, IO, ClONO2, BrONO2, ClOOCl, and H2O

Science.gov (United States)

Anderson, James G.

2005-01-01

This grant continued the research initially funded under NAG1-01095. This research addresses, through a combination of in situ and remote aircraft-borne instruments, the following scientific questions: Which mechanisms are responsible for the continuing erosion of ozone over midlatitudes of the Northern Hemisphere? Will the rapid loss of ozone over the Arctic in late winter continue to worsen over the next two decades? Are these large losses dynamically coupled to midlatitudes? Which mechanisms dictate the rate of exchange of material between the troposphere and stratosphere? How will these processes change in response to changes in climate? Will regional scale pollution episodes, that are emerging as predictable seasonal events, significantly affect the middle-to-upper troposphere chemical composition. If so, how will these changes alter the chemical composition of the middle world? What changes are predicted for the overworld? Why has the arctic stratosphere become colder in the late winter phase in recent years? Have increases in tropical upper troposphere temperatures increased the temperature gradient such as to change the trajectories of vertically propagating waves, thus reducing the effectiveness of the meridional circulation for transport of heat, momentum and ozone from the tropics to high latitudes?

The Chrysalis Opens? Photometry from the η Carinae Hubble Space Telescope Treasury Project, 2002-2006

Science.gov (United States)

Martin, J. C.; Davidson, Kris; Koppelman, M. D.

2006-12-01

During the past decade η Car has brightened markedly, possibly indicating a change of state. Here we summarize photometry gathered by the Hubble Space Telescope (HST) as part of the HST Treasury Project on this object. Our data include Space Telescope Imaging Spectrograph (STIS) CCD acquisition images, Advanced Camera for Surveys HRC images in four filters, and synthetic photometry in flux-calibrated STIS spectra. The HST's spatial resolution allows us to examine the central star separate from the bright circumstellar ejecta. Its apparent brightness continued to increase briskly during 2002-2006, especially after the mid-2003 spectroscopic event. If this trend continues, the central star will soon become brighter than its ejecta, quite different from the state that existed only a few years ago. One precedent may be the rapid change observed in 1938-1953. We conjecture that the star's mass-loss rate has been decreasing throughout the past century. This research was conducted as part of the η Car Hubble Space Telescope Treasury project via grant GO-9973 from the Space Telescope Science Institute. HST is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS5-26555. Some of the data presented in this paper were obtained from the Multimission Archive at the Space Telescope Science Institute (MAST). STScI is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS5-26555. Support for MAST for non-HST data is provided by the NASA Office of Space Science via grant NAG5-7584 and by other grants and contracts.

38 CFR 61.40 - Special needs grants-general.

Science.gov (United States)

2010-07-01

... (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.40 Special needs grants—general. (a) VA provides special needs grants to capital grant and per diem recipients under this part to assist with... that would change significantly the scope of the project for which a capital grant or per diem was...

38 CFR 61.11 - Applications for capital grants.

Science.gov (United States)

2010-07-01

... (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.11 Applications for capital grants. (a) To apply for a capital grant, an applicant must obtain from VA a capital grant application package and... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Applications for capital...

Carbon sequestration by patch fertilization: A comprehensive assessment using coupled physical-ecological-biogeochemical models: FINAL REPORT of grant Grant No. DE-FG02-04ER63726

Energy Technology Data Exchange (ETDEWEB)

Sarmiento, Jorge L; Gnanadesikan, Anand; Gruber, Nicolas

2007-06-21

This final report summarizes research undertaken collaboratively between Princeton University, the NOAA Geophysical Fluid Dynamics Laboratory on the Princeton University campus, the State University of New York at Stony Brook, and the University of California, Los Angeles between September 1, 2000, and November 30, 2006, to do fundamental research on ocean iron fertilization as a means to enhance the net oceanic uptake of CO2 from the atmosphere. The approach we proposed was to develop and apply a suite of coupled physical-ecologicalbiogeochemical models in order to (i) determine to what extent enhanced carbon fixation from iron fertilization will lead to an increase in the oceanic uptake of atmospheric CO2 and how long this carbon will remain sequestered (efficiency), and (ii) examine the changes in ocean ecology and natural biogeochemical cycles resulting from iron fertilization (consequences). The award was funded in two separate three-year installments: • September 1, 2000 to November 30, 2003, for a project entitled “Ocean carbon sequestration by fertilization: An integrated biogeochemical assessment.” A final report was submitted for this at the end of 2003 and is included here as Appendix 1. • December 1, 2003 to November 30, 2006, for a follow-on project under the same grant number entitled “Carbon sequestration by patch fertilization: A comprehensive assessment using coupled physical-ecological-biogeochemical models.” This report focuses primarily on the progress we made during the second period of funding subsequent to the work reported on in Appendix 1. When we began this project, we were thinking almost exclusively in terms of long-term fertilization over large regions of the ocean such as the Southern Ocean, with much of our focus being on how ocean circulation and biogeochemical cycling would interact to control the response to a given fertilization scenario. Our research on these types of scenarios, which was carried out largely during

Application for an IDRC Research Grant

International Development Research Centre (IDRC) Digital Library (Canada)

Indicate the approaches and methods that will be used to collect data as well as how the research ..... or diploma programs, short courses, student field work, postdoctoral training, or other scholarly activities. ..... E = excellent; G = good; F = fair.

30 CFR 735.14 - Coverage of grants.

Science.gov (United States)

2010-07-01

... systems, including data processing systems; (6) A planning process including a data base and information... ADMINISTRATION AND ENFORCEMENT § 735.14 Coverage of grants. (a) Program development grants. An agency may use... the initial administration and enforcement grant to the extent not covered by indirect costs or other...

38 CFR 61.10 - Capital grants-general.

Science.gov (United States)

2010-07-01

...) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.10 Capital grants—general. (a) VA provides capital grants to public or nonprofit private entities so they can assist homeless veterans by helping to... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Capital grants-general...

Crowdfunding for cardiovascular research.

Science.gov (United States)

Krittanawong, Chayakrit; Zhang, HongJu Janet; Aydar, Mehmet; Wang, Zhen; Sun, Tao

2018-01-01

The competition for public cardiovascular research grants has recently increased. Independent researchers are facing increasing competition for public research grant support and ultimately may need to seek alternative funding sources. Crowdfunding, a financing method of raising funds online by pooling together small donations from the online community to support a specific initiative, seems to have significant potential. However, the feasibility of crowdfunding for cardiovascular research remains unknown. Here, we performed exploratory data analysis of the feasibility of online crowdfunding in cardiovascular research. Copyright © 2017 Elsevier B.V. All rights reserved.

Taking Soft Skills for Granted?

Science.gov (United States)

Dutton, Gail

2012-01-01

The U.S. Department of Labor will award a total of $2 billion over the next four years through the Trade Adjustment Assistance Community College and Career Training Grant Program. Grants will support the development and improvement of postsecondary programs of two years or less that use evidence-based or innovative strategies to prepare students…

Do vehicle grants and vehicle adaptations grants promote transport mobility and community access for children with disabilities in Sweden?

Science.gov (United States)

Sjödin, Linda; Buchanan, Angus; Mundt, Beate; Karlsson, Emelie; Falkmer, Torbjörn

2012-02-01

A vast majority of the journeys made by children with disabilities in Sweden are in the family car, which usually is bought and adapted for the child with governmental subsidies. Despite the important philosophical views about accessible vehicles, little is known about the impact of vehicle adaptations on families' lives. The aim of the study was to investigate parent views about the impact of vehicle grants and vehicle adaptation grants on their children's transport mobility and community access. In total, 434 parents of children with disabilities in Sweden who had received vehicle grants and/or vehicle adaptation grants between 1998-2007 responded to a questionnaire comprising questions with both pre-selected and open-ended answers. A non-responder analysis was performed. Children with disabilities were found to increase their transport mobility and community access in society as vehicle grants and/or vehicle adaptation grants were given to their parents. Their travel patterns and their travel priorities with their family car indicated that family friends and relatives and leisure activities were frequently visited and prioritised destinations. The grants were linked to access to social and family activities, provided environmental gains and led to increased experienced security. The results also showed that the potential to make spontaneous trips had increased substantially and that families experienced feelings of freedom and enhanced community access. The non-responder analysis confirmed these results. According to parents, vehicle grants and vehicle adaptation grants for children with disabilities have a positive impact on the children's transport mobility and community access. © 2011 The Authors. Australian Occupational Therapy Journal © 2011 Occupational Therapy Australia.

Carleton to oversee $40 million lab grant

CERN Multimedia

Singer, Zev

2003-01-01

"Carleton University got a major gift yesterday, as the federal government announced the university will oversee a $40-million grant to run the world's deepest underground lab at the Sudbury Neutrino Observatory. Five other universities are partners in the project" (1/2 page).

ERC rewards CERN researchers

CERN Multimedia

Rosaria Marraffino

2015-01-01

The European Research Council (ERC) has awarded starting grants to Magdalena Kowalska, a member of the ISOLDE physics team, and Claude Duhr, CERN Theory Division. The funding will enable them to build their own research teams at CERN, engaging postdocs and PhD students.   Magdalena Kowalska and Claude Duhr. The ERC fosters scientific excellence in Europe through competitive funding. Its grants are awarded to projects headed by researchers – both beginning-of-career and established – via an open, peer-reviewed competition. In December 2014, Magdalena Kowalska and Claude Duhr were awarded grants to pursue research in ultra-sensitive nuclear magnetic resonance (NMR) in liquids and mathematical structures in scattering amplitudes, respectively. “Our research project aims to apply an ultra-sensitive NMR technique using radioisotopes to liquids in order to study the interaction of metal ions with biological molecules such as proteins, DNA or RNA,” says Mag...

7 CFR 1776.12 - Use of HWWS grant proceeds.

Science.gov (United States)

2010-01-01

... recipient may not use grant funds in any manner inconsistent with the terms of the grant agreement. ... eligible individuals. (b) A grant recipient may use HWWS grant funds to pay administrative expenses...

Identification of novel Theileria genotypes from Grant's gazelle.

Science.gov (United States)

Hooge, Janis; Howe, Laryssa; Ezenwa, Vanessa O

2015-08-01

Blood samples collected from Grant's gazelles (Nanger granti) in Kenya were screened for hemoparasites using a combination of microscopic and molecular techniques. All 69 blood smears examined by microscopy were positive for hemoparasites. In addition, Theileria/Babesia DNA was detected in all 65 samples screened by PCR for a ~450-base pair fragment of the V4 hypervariable region of the 18S rRNA gene. Sequencing and BLAST analysis of a subset of PCR amplicons revealed widespread co-infection (25/39) and the existence of two distinct Grant's gazelle Theileria subgroups. One group of 11 isolates clustered as a subgroup with previously identified Theileria ovis isolates from small ruminants from Europe, Asia and Africa; another group of 3 isolates clustered with previously identified Theileria spp. isolates from other African antelope. Based on extensive levels of sequence divergence (1.2-2%) from previously reported Theileria species within Kenya and worldwide, the Theileria isolates detected in Grant's gazelles appear to represent at least two novel Theileria genotypes.

Modified Monkman–Grant relationship for austenitic stainless steel foils

Energy Technology Data Exchange (ETDEWEB)

Osman Ali, Hassan, E-mail: hassaninsan@gmail.com [Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, 81310 UTM Skudai, Johor (Malaysia); Tamin, Mohd Nasir, E-mail: taminmn@fkm.utm.my [Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, 81310 UTM Skudai, Johor (Malaysia)

2013-02-15

Characteristics of creep deformation for austenitic stainless steel foils are examined using the modified Monkman–Grant equation. A series of creep tests are conducted on AISI 347 steel foils at 700 °C and different stress levels ranging from 54 to 221 MPa. Results showed that at lower stress levels below 110 MPa, the creep life parameters ε{sub min},ε{sub r},t{sub r} can be expressed using the modified Monkman–Grant equation with exponent m′= 0.513. This indicates significant deviation of the creep behavior from the first order reaction kinetics theory for creep (m′ = 1.0). The true tertiary creep damage in AISI 347 steel foil begins after 65.9% of the creep life of the foil has elapsed at stress levels above 150 MPa. At this high stress levels, Monkman–Grant ductility factor λ{sup ′} saturates to a value of 1.3 with dislocation-controlled deformation mechanisms operating. At low stress levels, λ{sup ′} increases drastically (λ{sup ′}=190 at 54 MPa) when slow diffusion-controlled creep is dominant.

7 CFR 3402.5 - Overview of National Needs Graduate and Postdoctoral Fellowship Grants Program.

Science.gov (United States)

2010-01-01

... (Continued) COOPERATIVE STATE RESEARCH, EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE FOOD AND... will provide funds for a limited number of grants to support graduate student stipends and cost-of... thesis/dissertation research travel allowances for a limited number of USDA Graduate Fellows. To...

Brownfields Grants Information

Data.gov (United States)

U.S. Environmental Protection Agency — This asset includes all types of information regarding Brownfields grant programs that subsidize/support Brownfield cleanup. This includes EPA's Brownfields Program...

US EPA CARE Grants/IGD: PERF_COMMUN_GRANTS_INT_MV

Data.gov (United States)

U.S. Environmental Protection Agency — This is a provisional dataset that contains point locations for the subset of Community Action for a Renewed Environment (CARE) grants given out by the US EPA. CARE...

US EPA EJ Grants/IGD: PERF_EJ_GRANTS_INT_MV

Data.gov (United States)

U.S. Environmental Protection Agency — This is a provisional dataset that contains point locations for all Environmental Justice (EJ) grants given out by the US EPA. There are many limitations to the data...

A Web Server for MACCS Magnetometer Data

Science.gov (United States)

Engebretson, Mark J.

1998-01-01

NASA Grant NAG5-3719 was provided to Augsburg College to support the development of a web server for the Magnetometer Array for Cusp and Cleft Studies (MACCS), a two-dimensional array of fluxgate magnetometers located at cusp latitudes in Arctic Canada. MACCS was developed as part of the National Science Foundation's GEM (Geospace Environment Modeling) Program, which was designed in part to complement NASA's Global Geospace Science programs during the decade of the 1990s. This report describes the successful use of these grant funds to support a working web page that provides both daily plots and file access to any user accessing the worldwide web. The MACCS home page can be accessed at http://space.augsburg.edu/space/MaccsHome.html.

76 FR 41297 - Grant Program To Build Tribal Energy Development Capacity

Science.gov (United States)

2011-07-13

.... Determine what process(es) and/or procedure(s) may be used to eliminate capacity gaps or sustain the... Ineligible for TEDC Grant Funding Feasibility studies and energy resource assessments; Purchase of resource assessment data; Research and development of speculative or unproven technologies; Purchase or lease of...

77 FR 19738 - Notice of Availability of Calendar Year 2013 Competitive Grant Funds

Science.gov (United States)

2012-04-02

... , or visit the grants competition Web site at www.grants.lsc.gov . SUPPLEMENTARY INFORMATION: The..., CA-19, CA-26, CA-29, CA- 30. Colorado CO-6, MCO, NCO-1. Delaware MDE. Florida FL-5, FL-13, FL-14,FL...

42 CFR 55a.102 - Who is eligible to apply for a Black Lung clinics grant?

Science.gov (United States)

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Who is eligible to apply for a Black Lung clinics... SERVICES GRANTS PROGRAM GRANTS FOR BLACK LUNG CLINICS General Provisions § 55a.102 Who is eligible to apply for a Black Lung clinics grant? Any State or public or private entity may apply for a grant under this...

Trapping of Solar Energetic Particles by Small-Scale Topology of Solar Wind Turbulence

Science.gov (United States)

Ruffolo, D.; Matthaeus, W. H.; Chuychai, P.

2004-05-01

The transport of energetic particles perpendicular to the mean magnetic field in space plasmas long has been viewed as a diffusive process. However, there is an apparent conflict between recent observations of solar energetic particles (SEP): 1) impulsive solar flares can exhibit ``dropouts" in which SEP intensity near Earth repeatedly disappears and reappears, indicating a filamentary distribution of SEPs and little diffusion across these boundaries. 2) Observations by the IMP-8 and Ulysses spacecraft, while they were on opposite sides of the Sun, showed similar time-intensity profiles for many SEP events, indicating rapid lateral diffusion of particles throughout the inner solar system within a few days. We explain these seemingly contradictory observations using a theoretical model, supported by computer simulations, in which many particles are temporarily trapped within topological structures in statistically homogeneous magnetic turbulence, and ultimately escape to diffuse at a much faster rate. This work was supported by the Thailand Research Fund, the Rachadapisek Sompoj Fund of Chulalongkorn University, and the NASA Sun-Earth Connections Theory Program (grant NAG5-8134).

Grant Application Development, Submission, Review, & Award

Science.gov (United States)

This infographic shows the National Cancer Institute general timeline progression through Grant Application Development, Submission, Review, and Award Infographic. In the first month, Applicant prepares and submits Grant Application to Grants.gov in response to FOA. In month two, The Center for Scientific Review (CSR) assigns applications that fall under the category of R01s, etc. to a Scientific Review Group (SRG) or the CSR assigns applications that fall under the category of Program Projects and Center Grants to NCI Division of Extramural Activities (DEA). Months four through five: First-level review by Scientific Review Group (SRG) for Scientific Merit: SRG assigns Impact Scores. Month five Summary Sstatements are prepared and are available to NCI Program staff and applicants. Month six, second-level review by National Cancer Advisory board (NCAB) for NCI Funding determination begins. NCAB makes recommendation to NCI Director, NCI develops funding plan, Applications selected for Funding, “Paylists” forwarded to Office of Grant Administration (OGA). Month ten, Award Negotiations and Issuance: Award issued, Award received by Institution, and Investigator begins work. www.cancer.gov Icons made by Freepik from http://www.flaticon.com is licensed by CC BY3.0

Prandtl-Ishlinskii hysteresis models for complex time dependent hysteresis nonlinearities

Czech Academy of Sciences Publication Activity Database

Al Janaideh, M.; Krejčí, Pavel

2012-01-01

Roč. 407, č. 9 (2012), s. 1365-1367 ISSN 0921-4526 R&D Projects: GA ČR GAP201/10/2315 Institutional research plan: CEZ:AV0Z10190503 Keywords : complex hysteresis * time dependent hysteresis * Prandtl-Ishlinskii model Subject RIV: BA - General Mathematics Impact factor: 1.327, year: 2012 http://www.sciencedirect.com/science/article/pii/S092145261100932X

Short communication: risk factors for methicillin-resistant Staphylococcus aureus colonization among HIV patients at hospital admission.

Science.gov (United States)

Lee, Linda K; Win, Mar Kyaw; Veeraraghavan, Meyyur A; Wong, Chia Siong; Chow, Angela L; Leo, Yee-Sin

2013-05-01

Methicillin-resistant Staphylococcus aureus (MRSA) is a nosocomial pathogen that has become increasingly prominent in hospitals and the community. HIV-positive patients may be one of the most MRSA-susceptible populations because of their immunocompromised status. At the Communicable Disease Centre, Tan Tock Seng Hospital, Singapore, we implemented a universal MRSA screening program and performed a case-control study to identify risk factors for MRSA colonization among 294 HIV patients at admission from January 2009 to January 2010. Among 54 HIV-positive patients who were MRSA positive at hospital admission, 16 (29.6%) were positive at the nares/axilla/groin (NAG; one combined swab), 14 (25.9%) were NAG and perianal positive, 3 (5.6%) were NAG and throat positive, 10 (18.5%) were NAG, perianal, and throat positive, 6 (11.1%) were throat positive, and 5 (9.3%) were perianal positive. Upon multivariate analysis, we found that age [odds ratio (OR)=1.04, 95% confidence interval (CI): 1.01-1.07, p=0.006] and CD4 count hospital admission.

The ARV roll out and the disability grant: a South African dilemma?

Science.gov (United States)

de Paoli, Marina Manuela; Mills, Elizabeth Anne; Grønningsaeter, Arne Backer

2012-02-16

Prior to the antiretroviral (ARV) drug roll out in 2004, people living with HIV (PLHIV) in South Africa received disability grants when they were defined as "AIDS-sick". In the absence of available and effective medication, a diagnosis of AIDS portended disability. The disability grant is a critical component of South Africa's social security system, and plays an important role in addressing poverty among PLHIV. Given the prevalence of unemployment and poverty, disability grants ensure access to essential resources, like food, for PLHIV. Following the ARV roll out in South Africa, PLHIV experienced improved health that, in turn, affected their grant eligibility. Our aim is to explore whether PLHIV reduced or stopped treatment to remain eligible for the disability grant from the perspectives of both PLHIV and their doctors. A mixed-methods design with concurrent triangulation was applied. We conducted: (1) in-depth semi-structured interviews with 29 PLHIV; (2) in-depth semi-structured interviews with eight medical doctors working in the public sector throughout the Cape Peninsula; (3) three focus group discussions with programme managers, stakeholders and community workers; and (4) a panel survey of 216 PLHIV receiving ARVs. Unemployment and poverty were the primary concerns for PLHIV and the disability grant was viewed as a temporary way out of this vicious cycle. Although loss of the disability grant significantly affected the well-being of PLHIV, they did not discontinue ARVs. However, in a number of subtle ways, PLHIV "tipped the scales" to lower the CD4 count without stopping ARVs completely. Grant criteria were deemed ad hoc, and doctors struggled to balance economic and physical welfare when assessing eligibility. It is crucial to provide sustainable economic support in conjunction with ARVs in order to make "positive living" a reality for PLHIV. A chronic illness grant, a basic income grant or an unemployment grant could provide viable alternatives when the

Cooperative research in space geodesy and crustal dynamics

Science.gov (United States)

1994-01-01

This research grant, which covered the period of July 1991 to August 1994, was concerned with a variety of topics within the geodesy and crustal dynamics fields. The specific topics of this grant included satellite tracking and gravity field determinations and crustal dynamics (this concentrated of space geodetic site stability for VLBI sites). Summaries of the specific research projects are included along with a list of publications and presentations supported by this research grant.

Program Spotlight: Dana Farber/Harvard Cancer Center Partnership Receives $8 Million Grant

Science.gov (United States)

The UMass Boston and Dana Farber/Harvard Cancer Center PACHE Partnership received a grant to start-up a Center for Personalized Cancer Therapy on the UMass Boston campus. The center is deigned to train underrepresented students to work in cancer research.

15 CFR 918.5 - Eligibility, qualifications, and responsibilities-Sea Grant Regional Consortia.

Science.gov (United States)

2010-01-01

... identification and communication of user communities' research and educational needs. (6) Relationships. The Sea... ability to obtain matching funds from non-Federal sources, such as State legislatures, university... Grant organizations. (3) Maintain an effective management framework and application of organizational...

Zambia - Innovation Grants

Data.gov (United States)

Millennium Challenge Corporation — The performance evaluation of the IGP is structured according to five phases of IGP implementation that we have identified for each grant cycle: start-up, selection,...

Feeding characteristics of sheep ( Ovis aries ) and Grant\\'s gazelles ...

African Journals Online (AJOL)

, neutral detergent fibre, acid detergent fibre, cellulose, lignin and in vitro dry matter digestibility. Sheep were predominantly grazers during both the dry and wet season while Grant's gazelles were mixed feeders, with a higher consumption of ...

The New York State Program for the Conservation and Preservation of Library Research Materials. Selected Press Clippings about Projects Funded by the Discretionary Grant Program, 1988/89 and 1989/90.

Science.gov (United States)

New York State Library, Albany. Div. of Library Development.

This document is composed of clippings from news publications and press releases about projects funded by the New York State Discretionary Grant Program for Conservation and Preservation of Library Research Materials, which annually awards $500,000 to libraries, archives, historical societies, and similar agencies in New York State through…

Welfare Financing : Grant Allocation and Efficiency

NARCIS (Netherlands)

Toolsema, L.A.; Allers, Maarten A.

Welfare is often administered locally, but financed through grants from the central government. This raises the question how the central government can prevent local governments from spending more than necessary. We analyze block grants used in The Netherlands, which depend on exogenous spending

Seeds of Innovation: Three Years of the Technology Innovation Challenge Grant Program.

Science.gov (United States)

Harris, Larry A.

This publication describes the 62 projects that received 5-year Technology Innovation Challenge Grants beginning in 1995, 1996, and 1997, with reviews of the projects occurring in late 1999 and early 2000. Part 1 of the report describes the Technology Innovation Challenge Grant (TICG) program and its importance. Part 2 contains the project…

Governmental Research Support Programs and Private Entities in Slovakia

Directory of Open Access Journals (Sweden)

Maliková Zuzana

2015-01-01

Full Text Available The paper analyses public subsidies aimed to enhance development and innovation in the Slovakian private sector. The paper reviews theoretical approaches of the necessity of public support to research and development activities in order to increase private investment in research and development. An overview of research and development support tools in Slovakia is presented. The analytical part of the work is oriented on a comparative analysis of two granting agencies in Slovakia [Agency for Research and Development (ARD and Agency of Operational Program Research and Development (OPRD]. Special attention is given to direct public financial support. Logit analysis showed a relationship between success of grant applicants and their characteristics. We find that the following have impact on success of the application: Age of the company, amount of the grant required, legal form of the company, and the agency to which the application for grant was submitted. Applicants with legal form Ltd. (limited liability company have a higher chance of receiving grant than other legal forms. The highest chance of success has a request for a grant of up to 500.000 €. According to the results of our analysis, the chance to obtain a grant decreases with each passing year.

Nitrifying aerobic granular sludge fermentation for releases of carbon source and phosphorus: The role of fermentation pH.

Science.gov (United States)

Zou, Jinte; Pan, Jiyang; He, Hangtian; Wu, Shuyun; Xiao, Naidong; Ni, Yongjiong; Li, Jun

2018-07-01

The effect of fermentation pH (uncontrolled, 4 and 10) on the releases of carbon source and phosphorus from nitrifying aerobic granular sludge (N-AGS) was investigated. Meanwhile, metal ion concentration and microbial community characterization were explored during N-AGS fermentation. The results indicated that N-AGS fermentation at pH 10 significantly promoted the releases of soluble chemical oxygen demand (SCOD) and total volatile fatty acids (TVFAs). However, SCOD and TVFA released from N-AGS were inhibited at pH 4. Moreover, acidic condition promoted phosphorus release (mainly apatite) from N-AGS during anaerobic fermentation. Nevertheless, alkaline condition failed to increase phosphorus concentration due to the formation of chemical-phosphate precipitates. Compared with the previously reported flocculent sludge fermentation, N-AGS fermentation released more SCOD and TVFAs, possibly due to the greater extracellular polymeric substances content and some hydrolytic-acidogenic bacteria in N-AGS. Therefore, N-AGS alkaline fermentation facilitated the carbon source recovery, while N-AGS acidic fermentation benefited the phosphorus recovery. Copyright © 2018. Published by Elsevier Ltd.

Role of Endocrine Gland-Derived Vascular Endothelial Growth Factor (EG-VEGF) and Its Receptors in Adrenocortical Tumors.

Science.gov (United States)

Heck, Dorothee; Wortmann, Sebastian; Kraus, Luitgard; Ronchi, Cristina L; Sinnott, Richard O; Fassnacht, Martin; Sbiera, Silviu

2015-12-01

Angiogenesis is essential for tumor growth and metastasis. Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) is an angiogenic factor predominantly expressed in steroidogenic organs like the adrenal gland, ovary, testes, and placenta. EG-VEGF has antiapoptotic, mitogenic, and chemoattractive properties mediated via the two G protein-coupled receptors prokineticin receptor 1 (PKR1) and prokineticin receptor 2 (PKR2). We investigated the expression of EG-VEGF and its receptors in a large number of normal adrenal glands (NAG), adrenocortical adenomas (ACA), and carcinomas (ACC) using real-time PCR (NAG, n = 12; ACA, n = 24; and ACC, n = 30) and immunohistochemistry (NAG, n = 9; ACA, n = 23; and ACC, n = 163) and evaluated its impact on patients' survival. EG-VEGF, PKR1, and PKR2 mRNA and protein are expressed in NAG and the vast majority of ACA and ACC samples. The mean EG-VEGF mRNA expression was significantly lower in ACC (606.5 ± 77.1 copies) compared to NAG (4,043 ± 1,111) and cortisol-producing adenomas (CPA) (4,433 ± 2,378) (p < 0.01 and p < 0.05, respectively). However, cytoplasmic and nuclear EG-VEGF protein expression was either significantly higher or similar in ACC (H score 2.4 ± 0.05, p < 0.05 and 1.7 ± 0.08, n.s., respectively) compared to NAG (1.8 ± 0.14 and 1.7 ± 0.2). Nuclear protein expression of either EG-VEGF or PKR1 or both is predictive for a higher mortality compared to patients without nuclear expression (hazard ratio (HR) = 5.15; 95% confidence interval (CI) = 1.24-21.36, n = 100, p = 0.02 independent of age, sex, and tumor stage). These findings suggest that EG-VEGF and its receptor PKR1 might play a role in the pathogenesis of adrenocortical tumors and could serve as prognostic markers for this rare malignant disease.

Update regarding the society of American Gastrointestinal and Endoscopic Surgeons (SAGES) grant distribution and impact on recipient's academic career.

Science.gov (United States)

DuCoin, Christopher; Petersen, Rebecca P; Urbach, David; Aggarwal, Rajesh; Madan, Atul K; Pryor, Aurora D

2018-07-01

Small seed grants strongly impact academic careers, result in future funding, and lead to increased involvement in surgical societies. We hypothesize that, in accordance with the SAGES Research and Career Development committee mission, there has been a shift in grant support from senior faculty to residents and junior faculty. We hypothesize that these junior physician-researchers are subsequently remaining involved with SAGES and advancing within their academic institutions. All current and previous SAGES grant recipients were surveyed through Survey Monkey™. Questions included current academic status and status at time of grant, ensuing funding, publication and presentation of grant, and impact on career. Results were verified through a Medline query. SAGES database was examined for involvement within the society. Respondent data were compared to 2009 data. One hundred and ninety four grants were awarded to 167 recipients. Of those, 75 investigators responded for a response rate 44.9%. 32% were trainees, 43% assistant professors, 16% associate professors, 3% full professors, 3% professors with tenure, and 3% in private practice. This is a shift from 2009 data with a considerable increase in funding of trainees by 19% and assistant professors by 10% and a decrease in funding of associate professors by 5% and professors by 10%. 41% of responders who were awarded the grant as assistant or associate professors had advanced to full professor and 99% were currently in academic medicine. Eighty-two percent indicated that they had completed their project and 93% believed that the award helped their career. All responders remained active in SAGES. SAGES has chosen to reallocate an increased percentage of grant money to more junior faculty members and residents. It appears that these grants may play a role in keeping recipients interested in the academic surgical realm and involved in the society while simultaneously helping them advance in faculty rank.

Role of carglumic acid in the treatment of acute hyperammonemia due to N-acetylglutamate synthase deficiency

Directory of Open Access Journals (Sweden)

Häberle J

2011-08-01

Full Text Available Johannes HäberleKinderspital Zürich, Abteilung Stoffwechsel, Zürich, SwitzerlandAbstract: N-acetylglutamate synthase (NAGS deficiency is a rare inborn error of metabolism affecting ammonia detoxification in the urea cycle. The product of NAGS is N-acetylglutamate which is the absolutely required allosteric activator of the first urea cycle enzyme carbamoylphosphate synthetase 1. In defects of NAGS, the urea cycle function can be severely affected resulting in fatal hyperammonemia in neonatal patients or at any later stage in life. NAGS deficiency can be treated with a structural analog of N-acetylglutamate, N-carbamyl-L-glutamate, which is available for enteral use as a licensed drug. Since NAGS deficiency is an extremely rare disorder, reports on the use of N-carbamyl-L-glutamate are mainly based on single patients. According to these, the drug is very effective in treating acute hyperammonemia by avoiding the need for detoxification during the acute metabolic decompensation. Also during long-term treatment, N-carbamyl-L-glutamate is effective in maintaining normal plasma ammonia levels and avoiding the need for additional drug therapy or protein-restricted diet. Open questions remain which concern the optimal dosage in acute and long-term use of N-carbamyl-L-glutamate and potential additional disorders in which the drug might also be effective in treating acute hyperammonemia. This review focuses on the role of N-carbamyl-L-glutamate for the treatment of acute hyperammonemia due to primary NAGS deficiency but will briefly discuss the current knowledge on the role of N-carbamyl-L-glutamate for treatment of secondary NAGS deficiencies.Keywords: carglumic acid, carbamylglutamate, N-carbamyl-L-glutamate, N-acetylglutamate synthase deficiency, NAGS deficiency, hyperammonemia

77 FR 4984 - Solicitation of Input From Stakeholders Regarding the Capacity Building Grants for Non Land Grant...

Science.gov (United States)

2012-02-01

... Stakeholders Regarding the Capacity Building Grants for Non Land Grant Colleges of Agriculture Institutions... and request for stakeholder input. SUMMARY: The National Institute of Food and Agriculture (NIFA) is... of the Secretary of Agriculture in soliciting public comments and stakeholder input from interested...

WE-G-BRB-02: The Role of Program Project Grants in Study of 3D Conformal Therapy, Dose Escalation and Motion Management

International Nuclear Information System (INIS)

Fraass, B.

2015-01-01

Over the past 20 years the NIH has funded individual grants, program projects grants, and clinical trials which have been instrumental in advancing patient care. The ways that each grant mechanism lends itself to the different phases of translating research into clinical practice will be described. Major technological innovations, such as IMRT and proton therapy, have been advanced with R01-type and P01-type funding and will be discussed. Similarly, the role of program project grants in identifying and addressing key hypotheses on the potential of 3D conformal therapy, normal tissue-guided dose escalation and motion management will be described. An overview will be provided regarding how these technological innovations have been applied to multi-institutional NIH-sponsored trials. Finally, the panel will discuss regarding which research questions should be funded by the NIH to inspire the next advances in radiation therapy. Learning Objectives: Understand the different funding mechanisms of the NIH Learn about research advances that have led to innovation in delivery Review achievements due to NIH-funded program project grants in radiotherapy over the past 20 years Understand example advances achieved with multi-institutional clinical trials NIH

Identification of novel Theileria genotypes from Grant's gazelle

Directory of Open Access Journals (Sweden)

Janis Hooge

2015-08-01

Full Text Available Blood samples collected from Grant's gazelles (Nanger granti in Kenya were screened for hemoparasites using a combination of microscopic and molecular techniques. All 69 blood smears examined by microscopy were positive for hemoparasites. In addition, Theileria/Babesia DNA was detected in all 65 samples screened by PCR for a ~450-base pair fragment of the V4 hypervariable region of the 18S rRNA gene. Sequencing and BLAST analysis of a subset of PCR amplicons revealed widespread co-infection (25/39 and the existence of two distinct Grant's gazelle Theileria subgroups. One group of 11 isolates clustered as a subgroup with previously identified Theileria ovis isolates from small ruminants from Europe, Asia and Africa; another group of 3 isolates clustered with previously identified Theileria spp. isolates from other African antelope. Based on extensive levels of sequence divergence (1.2–2% from previously reported Theileria species within Kenya and worldwide, the Theileria isolates detected in Grant's gazelles appear to represent at least two novel Theileria genotypes.

High Energy Solar Spectroscopic Imager (HESSI) Team Investigations

Science.gov (United States)

Emslie, A. Gordon

1998-01-01

This report covers activities on the above grant for the period through the end of September 1997. The work originally proposed to be performed under a three-year award was converted at that time to a two-year award for the remainder of the period, and is now funded under award NAGS-4027 through Goddard Space Flight Center. The P.I. is a co-investigator on the High Energy Solar Spectroscopic Imager (HESSI) team, selected as a Small-Class Explorer (SNMX) mission in 1997. He has also been a participant in the Space Physics Roadmap Planning Group. Our research has been strongly influenced by the NASA mission opportunities related to these activities. The report is subdivided into four sections, each dealing with a different aspect of our research within this guiding theme. Personnel involved in this research at UAH include the P.I. and graduate students Michele Montgomery and Amy Winebarger. Much of the work has been carried out in collaboration with investigators at other institutions, as detailed below. Attachment: Laser wakefield acceleration and astrophysical applications.

7 CFR 1940.589 - Rural Business Enterprise Grants.

Science.gov (United States)

2010-01-01

... 7 Agriculture 13 2010-01-01 2009-01-01 true Rural Business Enterprise Grants. 1940.589 Section 1940.589 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE... Loan and Grant Program Funds § 1940.589 Rural Business Enterprise Grants. (a) Amount available for...

7 CFR 1703.121 - Approved purposes for grants.

Science.gov (United States)

2010-01-01

... Approved purposes for grants. For distance learning and telemedicine projects, grants shall finance only... studies relating to the establishment or expansion of the phase of the project that is being financed with... initial capital assets associated with the project. The following are approved grant purposes: (a...

Heterogeneous and Evolving Distributions of Pluto's Volatile Surface Ices

Science.gov (United States)

Grundy, William M.; Olkin, C. B.; Young, L. A.; Buie, M. W.; Young, E. F.

2013-10-01

We report observations of Pluto's 0.8 to 2.4 µm reflectance spectrum with IRTF/SpeX on 70 nights over the 13 years from 2001 to 2013. The spectra show numerous vibrational absorption features of simple molecules CH4, CO, and N2 condensed as ices on Pluto's surface. These absorptions are modulated by the planet's 6.39 day rotation period, enabling us to constrain the longitudinal distributions of the three ices. Absorptions of CO and N2 are concentrated on Pluto's anti-Charon hemisphere, unlike absorptions of less volatile CH4 ice that are offset by roughly 90° from the longitude of maximum CO and N2 absorption. In addition to the diurnal/longitudinal variations, the spectra show longer term trends. On decadal timescales, Pluto's stronger CH4 absorption bands have deepened, while the amplitude of their diurnal variation has diminished, consistent with additional CH4 absorption by high northern latitude regions rotating into view as the sub-Earth latitude moves north (as defined by the system's angular momentum vector). Unlike the CH4 absorptions, Pluto's CO and N2 absorptions are declining over time, suggesting more equatorial or southerly distributions of those species. The authors gratefully thank the staff of IRTF for their tremendous assistance over the dozen+ years of this project. The work was funded in part by NSF grants AST-0407214 and AST-0085614 and NASA grants NAG5-4210 and NAG5-12516.

38 CFR 61.16 - Matching funds for capital grants.

Science.gov (United States)

2010-07-01

... capital grants. 61.16 Section 61.16 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.16 Matching funds for capital grants. The amount of a capital grant may not exceed 65 percent of the total cost of the project for which the...

Is it timing or backdating of option grants?

NARCIS (Netherlands)

van der Goot, T.

2010-01-01

Using a unique dataset from the Netherlands, we investigate three questions of interest. First, we explore the effects of a rule change in September 2002 on option grant dates. Second, we examine the retroactive backdating of option grant dates. Finally, we look at the timing of option grant dates

FEMA Hazard Mitigation Grants Program Summary - API

Data.gov (United States)

Department of Homeland Security — The Hazard Mitigation Grant Program (HMGP, CFDA Number: 97.039) provides grants to States and local governments to implement long-term hazard mitigation measures...

75 FR 60781 - Announcement of Funding Awards for Fiscal Year 2010 Doctoral Dissertation Research Grant Program

Science.gov (United States)

2010-10-01

... Street, New York, NY 10011. Grant: $25,000 to Jamie Taylor. 17. Board of Trustee of the University of... INFORMATION CONTACT: Susan Brunson, Office of University Partnerships, U.S. Department of Housing and Urban... awarded for a two-year period. The Office of University Partnerships under the Assistant Secretary for...

Doing Business with the Office of Naval Research

Science.gov (United States)

2012-08-01

DOING BUSINESS WITH THE OFFICE OF NAVAL RESEARCH Ms. Vera M. Carroll Acquisition Branch Head ONR BD 251 1 Report Documentation Page Form...COVERED 00-00-2012 to 00-00-2012 4. TITLE AND SUBTITLE Doing Business with the Office of Naval Research 5a. CONTRACT NUMBER 5b. GRANT NUMBER

30 CFR 285.508 - What rent payments must I pay on ROW grants or RUE grants associated with renewable energy projects?

Science.gov (United States)

2010-07-01

... RUE grants associated with renewable energy projects? 285.508 Section 285.508 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF... § 285.508 What rent payments must I pay on ROW grants or RUE grants associated with renewable energy...

38 CFR 61.44 - Awarding special needs grants.

Science.gov (United States)

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Awarding special needs... (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.44 Awarding special needs grants. (a... applicable, will be conditionally selected to receive a special needs grant in accordance with their ranked...

AMF 1 Site Science

Energy Technology Data Exchange (ETDEWEB)

Miller, Mark Alan [Rutgers Univ., New Brunswick, NJ (United States)

2016-08-18

This report documents progress on DOE Grant# DE-FG02-08ER64531 funded by the Department of Energy’s Atmospheric Systems Research (ASR) program covering the period between its inception in 2008 and its conclusion in 2014. The Atmospheric Radiation Measurement (ARM) Program’s Mobile Facility #1 (AMF#1) is a collection of state-of-the art atmospheric sensing systems including remote and in situ instrumentation designed to characterize the atmospheric column above and in the immediate vicinity of the deployment location. The grant discussed in this report funded the activities of the AMF#1 Site Scientist Team. Broad responsibilities of this team included examining new deployment sites and recommending instrument deployment configurations; data quality control during the early stages of deployments and for certain instruments through the course of the deployment; scientific outreach in the host country or location (particularly international deployments); scientific research oriented toward basic questions about cloud physics and radiation transfer in the deployment region; and training of Ph.D. students to conduct future research relevant to the Atmospheric Systems Research (ASR) program.

36 CFR 1206.90 - Must I acknowledge NHPRC grant support?

Science.gov (United States)

2010-07-01

....90 Must I acknowledge NHPRC grant support? Yes, grantee institutions, grant project directors, or grant staff personnel may publish results of any work supported by an NHPRC grant without review by the...

7 CFR 1944.426 - Grant closeout.

Science.gov (United States)

2010-01-01

... Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... appropriate, he/she will promptly inform the grantee by the use of exhibit B-3 of subpart B of part 1900 of... 1900 of this chapter. (d) Grant termination. The State Director may terminate the grant agreement...

7 CFR 1944.543 - Grant monitoring.

Science.gov (United States)

2010-01-01

... 7 Agriculture 13 2010-01-01 2009-01-01 true Grant monitoring. 1944.543 Section 1944.543 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... monitoring. Each grant will be monitored by FmHA or its successor agency under Public Law 103-354 to ensure...

Local government grants for private schools

Directory of Open Access Journals (Sweden)

Justyna Orlikowska

2016-03-01

Full Text Available This article aims to analyze the educational grants from budget of local government. Author presented procedures about establish private schools and educational institutions and explained selected concepts about units of education. The article presents selected judgment from SN and NSA in disputes about grants for private schools.

Attenuation of Microbial Stress Due to Nano-Ag and Nano-TiO2 Interactions under Dark Conditions.

Science.gov (United States)

Wilke, Carolyn M; Tong, Tiezheng; Gaillard, Jean-François; Gray, Kimberly A

2016-10-04

Engineered nanomaterials (ENMs) are incorporated into thousands of commercial products, and their release into environmental systems creates complex mixtures with unknown toxicological outcomes. To explore this scenario, we probe the chemical and toxicological interactions of nanosilver (n-Ag) and nanotitania (n-TiO 2 ) in Lake Michigan water, a natural aqueous medium, under dark conditions. We find that the presence of n-Ag induces a stress response in Escherichia coli, as indicated by a decrease in ATP production observed at low concentrations (in the μg L -1 range), with levels that are environmentally relevant. However, when n-Ag and n-TiO 2 are present together in a mixture, n-TiO 2 attenuates the toxicity of n-Ag at and below 20 μg L -1 by adsorbing Ag + (aq) . We observe, however, that toxic stress cannot be explained by dissolved silver concentrations alone and, therefore, must also depend on silver associated with the nanoscale fraction. Although the attenuating effect of n-TiO 2 on n-Ag's toxicity is limited, this study emphasizes the importance of probing the toxicity of ENM mixtures under environmental conditions to assess how chemical interactions between nanoparticles change the toxicological effects of single ENMs in unexpected ways.

Relation between Mechanical Properties and Pyrolysis Temperature of Phenol Formaldehyde Resin for Gas Separation Membranes

Czech Academy of Sciences Publication Activity Database

Šupová, Monika; Svítilová, Jaroslava; Chlup, Zdeněk; Černý, Martin; Weishauptová, Zuzana; Suchý, Tomáš; Machovič, Vladimír; Sucharda, Zbyněk; Žaloudková, Margit

2012-01-01

Roč. 56, č. 1 (2012), s. 40-49 ISSN 0862-5468 R&D Projects: GA ČR GA203/09/1327 Institutional research plan: CEZ:AV0Z30460519; CEZ:AV0Z20410507 Keywords : glassy carbon * membranes * mechanical properties Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 0.418, year: 2012 http://www.ceramics-silikaty.cz/2012/pdf/2012_01_40.pdf

Final Report for Grant DE-FG02-91ER40690 for the period 12/1/2010 to 4/30/2014

Energy Technology Data Exchange (ETDEWEB)

Durkin, Stan [The Ohio State Uiniversity, Columbus, OH (United States); Hill, Chris [The Ohio State Uiniversity, Columbus, OH (United States); Kass, Richard [The Ohio State Uiniversity, Columbus, OH (United States); Braaten, Eric [The Ohio State Uiniversity, Columbus, OH (United States); Mathur, Samir [The Ohio State Uiniversity, Columbus, OH (United States); Raby, Stuart [The Ohio State Uiniversity, Columbus, OH (United States); Shigemitsu, Junko [The Ohio State Uiniversity, Columbus, OH (United States); Gan, K. K. [The Ohio State Uiniversity, Columbus, OH (United States); Kagan, Harris [The Ohio State Uiniversity, Columbus, OH (United States); Hughes, Richard E. [The Ohio State Uiniversity, Columbus, OH (United States); Winer, Brian L. [The Ohio State Uiniversity, Columbus, OH (United States); Honscheid, Klaus [The Ohio State Uiniversity, Columbus, OH (United States)

2014-07-22

This is the final report for The Ohio State University high energy physics grant DE-FG02- 91ER40690. The activities of the various Tasks are briefy summarized over the previous grant period. The support from the Department of Energy is greatly appreciated.

30 CFR 285.435 - How can I relinquish a lease or a grant or parts of a lease or grant?

Science.gov (United States)

2010-07-01

..., DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER... relinquishment application with MMS. A relinquishment takes effect on the date we approve your application... obligations under the lease or grant. (b) Your relinquishment application must include: (1) Name; (2) Contact...

Local Government Responses to Education Grants.

Science.gov (United States)

Fisher, Ronald C.; Papke, Leslie E.

2000-01-01

Provides a primer for policymakers about the economics of education grants and draws implications for school finance reform. Includes an overview of the types of education grants that states and the federal government have used to aid local spending and summarizes findings from states' experiences with different forms of education finance.…

42 CFR 38.5 - Grant assistance.

Science.gov (United States)

2010-10-01

... nonprofit agencies and organizations which are located or do business primarily in the area affected by the... part 16—Procedures of the Departmental Grant Appeals Board 45 CFR part 74—Administration of grants 45... regulations of this part, the terms and the conditions of the award, and the applicable cost principles...

Structures of the N-acetyltransferase domain of Xylella fastidiosa N-acetyl-L-glutamate synthase/kinase with and without a His tag bound to N-acetyl-L-glutamate.

Science.gov (United States)

Zhao, Gengxiang; Jin, Zhongmin; Allewell, Norma M; Tuchman, Mendel; Shi, Dashuang

2015-01-01

Structures of the catalytic N-acetyltransferase (NAT) domain of the bifunctional N-acetyl-L-glutamate synthase/kinase (NAGS/K) from Xylella fastidiosa bound to N-acetyl-L-glutamate (NAG) with and without an N-terminal His tag have been solved and refined at 1.7 and 1.4 Å resolution, respectively. The NAT domain with an N-terminal His tag crystallized in space group P4(1)2(1)2, with unit-cell parameters a=b=51.72, c=242.31 Å. Two subunits form a molecular dimer in the asymmetric unit, which contains ∼41% solvent. The NAT domain without an N-terminal His tag crystallized in space group P21, with unit-cell parameters a=63.48, b=122.34, c=75.88 Å, β=107.6°. Eight subunits, which form four molecular dimers, were identified in the asymmetric unit, which contains ∼38% solvent. The structures with and without the N-terminal His tag provide an opportunity to evaluate how the His tag affects structure and function. Furthermore, multiple subunits in different packing environments allow an assessment of the plasticity of the NAG binding site, which might be relevant to substrate binding and product release. The dimeric structure of the X. fastidiosa N-acetytransferase (xfNAT) domain is very similar to that of human N-acetyltransferase (hNAT), reinforcing the notion that mammalian NAGS is evolutionally derived from bifunctional bacterial NAGS/K.

Federal Research and Development Funding: FY2014

Science.gov (United States)

2014-02-19

1.12 billion for FY2014. The FY2014 request proposed $155 million to replace the agency’s Southeast Poultry Disease Research Laboratory in Athens...formula funding, and special grants. 94 U.S. Department of Agriculture, “Statement by Thomas J

View all initiatives | IDRC - International Development Research ...

International Development Research Centre (IDRC) Digital Library (Canada)

The Science Granting Councils Initiative in Sub-Saharan Africa is focused on strengthening the capacities of science granting councils in order to support research and evidence-based policies that will contribute to economic and social development in Sub-Saharan Africa. We fund researchers driving global change.

Closeout for U.S. Department of Energy Final Technical Report for University of Arizona grant DOE Award Number DE-FG03-95ER40906 From 1 February 1995 to 31 January 2004 Grant title: Theory and Phenomenology of Strong and Weak High Energy Physics (Task A) and Experimental Elementary Particle Physics (Task B)

Energy Technology Data Exchange (ETDEWEB)

Rutherfoord, John; Toussaint, Doug; Sarcevic, Ina

2005-03-03

The following pages describe the high energy physics program at the University of Arizona which was funded by DOE grant DE-FG03-95ER40906, for the period 1 February 1995 to 31 January 2004. In this report, emphasis was placed on more recent accomplishments. This grant was divided into two tasks, a theory task (Task A) and an experimental task (Task B but called Task C early in the grant period) with separate budgets. Faculty supported by this grant, for at least part of this period, include, for the theory task, Adrian Patrascioiu (now deceased), Ina Sarcevic, and Douglas Toussaint., and, for the experimental task, Elliott Cheu, Geoffrey Forden, Kenneth Johns, John Rutherfoord, Michael Shupe, and Erich Varnes. Grant monitors from the Germantown DOE office, overseeing our grant, changed over the years. Dr. Marvin Gettner covered the first years and then he retired from the DOE. Dr. Patrick Rapp worked with us for just a few years and then left for a position at the University of Puerto Rico. Dr. Kathleen Turner took his place and continues as our grant monitor. The next section of this report covers the activities of the theory task (Task A) and the last section the activities of the experimental task (Task B).

Closeout for U.S. Department of Energy Final Technical Report for University of Arizona grant DOE Award Number DE-FG03-95ER40906 From 1 February 1995 to 31 January 2004 Grant title: Theory and Phenomenology of Strong and Weak High Energy Physics (Task A) and Experimental Elementary Particle Physics (Task B)

International Nuclear Information System (INIS)

Rutherfoord, John; Toussaint, Doug; Sarcevic, Ina

2005-01-01

The following pages describe the high energy physics program at the University of Arizona which was funded by DOE grant DE-FG03-95ER40906, for the period 1 February 1995 to 31 January 2004. In this report, emphasis was placed on more recent accomplishments. This grant was divided into two tasks, a theory task (Task A) and an experimental task (Task B but called Task C early in the grant period) with separate budgets. Faculty supported by this grant, for at least part of this period, include, for the theory task, Adrian Patrascioiu (now deceased), Ina Sarcevic, and Douglas Toussaint., and, for the experimental task, Elliott Cheu, Geoffrey Forden, Kenneth Johns, John Rutherfoord, Michael Shupe, and Erich Varnes. Grant monitors from the Germantown DOE office, overseeing our grant, changed over the years. Dr. Marvin Gettner covered the first years and then he retired from the DOE. Dr. Patrick Rapp worked with us for just a few years and then left for a position at the University of Puerto Rico. Dr. Kathleen Turner took his place and continues as our grant monitor. The next section of this report covers the activities of the theory task (Task A) and the last section the activities of the experimental task (Task B)

ERC supports antihydrogen research

CERN Multimedia

Katarina Anthony

2013-01-01

As part of a Europe-wide effort to promote high-level research, the European Research Council (ERC) has awarded a €2.14 million grant to ALPHA spokesperson Jeffrey Hangst, which will further the collaboration’s study of the antihydrogen spectrum. The grant will be used to purchase laser spectroscopy equipment for the new ALPHA-2 set-up.   ALPHA Spokesperson, Jeffrey Hangst, in front of the new ALPHA-2 set-up. The incorporation of lasers into ALPHA-2 will allow the team to take precise measurements of trapped antihydrogen. Among the new equipment financed by the grant will be a high-precision laser and stabilisation system to study the transition from the ground state to the first excited state in antihydrogen. As this spectral line is very well known in hydrogen, its study in antihydrogen will provide essential data for matter/antimatter symmetry investigations. “The grant has come at a perfect time for us,” says Jeffrey Hangst. “We wil...

Differences in research funding for women scientists: a systematic comparison of UK investments in global infectious disease research during 1997-2010.

Science.gov (United States)

Head, Michael G; Fitchett, Joseph R; Cooke, Mary K; Wurie, Fatima B; Atun, Rifat

2013-12-09

There has not previously been a systematic comparison of awards for research funding in infectious diseases by sex. We investigated funding awards to UK institutions for all infectious disease research from 1997 to 2010, across disease categories and along the research and development continuum. Systematic comparison. Data were obtained from several sources for awards from the period 1997 to 2010 and each study assigned to-disease categories; type of science (preclinical, phases I-III trials, product development, implementation research); categories of funding organisation. Fold differences and statistical analysis were used to compare total investment, study numbers, mean grant and median grant between men and women. 6052 studies were included in the final analysis, comprising 4357 grants (72%) awarded to men and 1695 grants (28%) awarded to women, totalling £2.274 billion. Of this, men received £1.786 billion (78.5%) and women £488 million (21.5%). The median value of award was greater for men (£179 389; IQR £59 146-£371 977) than women (£125 556; IQR £30 982-£261 834). Awards were greater for male principal investigators (PIs) across all infectious disease systems, excepting neurological infections and sexually transmitted infections. The proportion of total funding awarded to women ranged from 14.3% in 1998 to 26.8% in 2009 (mean 21.4%), and was lowest for preclinical research at 18.2% (£285.5 million of £1.573 billion) and highest for operational research at 30.9% (£151.4 million of £489.7 million). There are consistent differences in funding received by men and women PIs: women have fewer funded studies and receive less funding in absolute and in relative terms; the median funding awarded to women is lower across most infectious disease areas, by funder, and type of science. These differences remain broadly unchanged over the 14-year study period.

7 CFR 1948.92 - Grant approval and fund obligation.

Science.gov (United States)

2010-01-01

..., RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF... 1900-B. (d) If a grant is recommended, Form FmHA or its successor agency under Public Law 103-354 440-1...

CAPCAL, 3-D Capacitance Calculator for VLSI Purposes

International Nuclear Information System (INIS)

Seidl, Albert; Klose, Helmut; Svoboda, Mildos

2004-01-01

1 - Description of program or function: CAPCAL is devoted to the calculation of capacitances of three-dimensional wiring configurations are typically used in VLSI circuits. Due to analogies in the mathematical description also conductance and heat transport problems can be treated by CAPCAL. To handle the problem using CAPCAL same approximations have to be applied to the structure under investigation: - the overall geometry has to be confined to a finite domain by using symmetry-properties of the problem - Non-rectangular structures have to be simplified into an artwork of multiple boxes. 2 - Method of solution: The electrical field is described by the Laplace-equation. The differential equation is discretized by using the finite difference method. NEA-1327/01: The linear equation system is solved by using a combined ADI-multigrid method. NEA-1327/04: The linear equation system is solved by using a conjugate gradient method for CAPCAL V1.3. NEA-1327/05: The linear equation system is solved by using a conjugate gradient method for CAPCAL V1.3. 3 - Restrictions on the complexity of the problem: NEA-1327/01: Certain restrictions of use may arise from the dimensioning of arrays. Field lengths are defined via PARAMETER-statements which can easily by modified. If the geometry of the problem is defined such that Neumann boundaries are dominating the convergence of the iterative equation system solver is affected

77 FR 61048 - Distracted Driving Grant Program

Science.gov (United States)

2012-10-05

... DEPARTMENT OF TRANSPORTATION National Highway Traffic Safety Administration Distracted Driving Grant Program AGENCY: National Highway Traffic Safety Administration (NHTSA), Department of... distracted driving grants on August 24, 2012. In this notice, DOT is extending the application submission...

7 CFR 4290.2000 - Operational Assistance Grants to RBICs.

Science.gov (United States)

2010-01-01

... Regulatory Capital raised by the RBIC at the time of licensing or $1,000,000. (d) Term. Operational... Smaller Enterprises to which it either has made, or expects to make, a Financing. (c) Amount of grant...

Grants Mining District

Science.gov (United States)

The Grants Mineral Belt was the focus of uranium extraction and production activities from the 1950s until the late 1990s. EPA is working with state, local, and federal partners to assess and address health risks and environmental effects of the mines

Survey of organizational research climates in three research intensive, doctoral granting universities.

Science.gov (United States)

Wells, James A; Thrush, Carol R; Martinson, Brian C; May, Terry A; Stickler, Michelle; Callahan, Eileen C; Klomparens, Karen L

2014-12-01

The Survey of Organizational Research Climate (SOuRCe) is a new instrument that assesses dimensions of research integrity climate, including ethical leadership, socialization and communication processes, and policies, procedures, structures, and processes to address risks to research integrity. We present a descriptive analysis to characterize differences on the SOuRCe scales across departments, fields of study, and status categories (faculty, postdoctoral scholars, and graduate students) for 11,455 respondents from three research-intensive universities. Among the seven SOuRCe scales, variance explained by status and fields of study ranged from 7.6% (Advisor-Advisee Relations) to 16.2% (Integrity Norms). Department accounted for greater than 50% of the variance explained for each of the SOuRCe scales, ranging from 52.6% (Regulatory Quality) to 80.3% (Integrity Inhibitors). It is feasible to implement this instrument in large university settings across a broad range of fields, department types, and individual roles within academic units. Published baseline results provide initial data for institutions using the SOuRCe who wish to compare their own research integrity climates. © The Author(s) 2014.

An analysis of the NIH-supported sickle cell disease research portfolio.

Science.gov (United States)

Gavini, Nara; Hoots, W Keith; Mensah, George A; Hanspal, Manjit

2015-02-01

Sickle cell disease (SCD), an inherited blood disorder is due to a single amino acid substitution on the beta chain of hemoglobin, and is characterized by anemia, severe infections, acute and chronic pain, and multi-organ damage. The National Institutes of Health (NIH) is dedicated to support basic, translational and clinical science research to improve care and ultimately, to find a cure for SCD that causes such suffering. This report provides a detailed analysis of grants funded by the NIH for SCD research in Fiscal Years 2007 through 2013. During this period, the NIH supported 247 de novo grants totaling $272,210,367 that address various aspects of SCD. 83% of these funds supported research project grants investigating the following 5 scientific themes: Pathology of Sickle Red Blood Cells; Globin Gene Expression; Adhesion and Vascular Dysfunction; Neurological Complications and Organ-specific Dysfunction; and Pain Management and Intervention. The remaining 17% of total funds supported career development and training grants; Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants; large Center grants; and Conference grants. Further analysis showed that the National Heart, Lung, and Blood Institute (NHLBI) is the largest funder of SCD research within NIH with 67% of total grants, contributing 77% of total funds; followed by the National Institute for Digestive Diseases and Kidney (NIDDK) that is funding 19% of grants, contributing 13% of total funds. The remaining 14% of grants totaling 10% of the funds were supported by all other NIH Institutes/Centers (ICs) combined. In summary, the NIH is using multiple funding mechanisms to support a sickle cell disease research agenda that is intended to advance the detection, treatment, and cure of this debilitating genetic disease. Published by Elsevier Inc.

Canada-Africa Research Exchange Grants Phase II | IDRC ...

International Development Research Centre (IDRC) Digital Library (Canada)

It will contribute to IDRC's long-term commitment to the development of research ... IDRC congratulates first cohort of Women in Climate Change Science Fellows ... In partnership with UNESCO's Organization for Women in Science for the Developing World ... Copyright · Open access policy · Privacy policy · Research ethics ...

75 FR 54330 - Intent To Grant an Exclusive Field of Use License of a U.S. Government-Owned Patent Application

Science.gov (United States)

2010-09-07

... DEPARTMENT OF DEFENSE Department of the Army Intent To Grant an Exclusive Field of Use License of a U.S. Government-Owned Patent Application AGENCY: Department of the Army, DoD. ACTION: Notice... intent to grant an exclusive, revocable license for the field of use in the research reagent market to...

26 CFR 1.41-0 - Table of contents.

Science.gov (United States)

2010-04-01

....41-1Credit for increasing research activities. (a) Amount of credit. (b) Introduction to regulations... purpose. (6) Substantially all requirement. (7) Use of computers and information technology. (8... research expenses. (8) Research in the social sciences, etc. (9) Research funded by any grant, contract, or...

Dopravně závislé řízení silničního provozu ve městech (2. část)

Czech Academy of Sciences Publication Activity Database

Nagy, Ivan; Kratochvílová, Jitka; Pecherková, Pavla

2007-01-01

Roč. 13, č. 7 (2007), s. 61-64 ISSN 1210-9592 R&D Projects: GA MDS(CZ) 1F43A/003/120 Institutional research plan: CEZ:AV0Z10750506 Keywords : Traffic microregion * model * forecasting * filter ing * engineering Subject RIV: BC - Control Systems Theory http://as.utia.cz/publications/2007/NagHomPec_07.pdf

Analysis of the temporal expression of chemokines and chemokine receptors during experimental granulomatous inflammation: role and expression of MIP-1α and MCP-1

Science.gov (United States)

Carollo, Maria; Hogaboam, Cory M; Kunkel, Stephen L; Delaney, Stephen; Christie, Mark I; Perretti, Mauro

2001-01-01

Chemokine expression and function was monitored in an experimental model of granulomatous tissue formation after injection of croton oil in complete Freund's adjuvant (CO/CFA) into mouse dorsal air-pouches up to 28 days. In the first week, mast cell degranulation and leukocyte influx (mononuclear cell, MNC, and polymorphonuclear cell, PMN) were associated with CXCR2, KC and macrophage inflammatory protein (MIP)-2 mRNA expression, as determined by TaqMan® reverse transcriptase-polymerase chain reaction. KC (∼400 pg mg protein−1, n=12) and MIP-2 (∼800 pg mg protein−1, n=12) proteins peaked at day 7, together with myeloperoxidase (MPO) activity. Highest MIP-1α (>1 ng mg protein−1, n=12) levels were measured at day 3. After day 7, a gradual increase in CCR2 and CCR5 mRNA, monocyte chemoattractant protein (MCP)-1 mRNA and protein expression was measured. MCP-1 protein peaked at day 21 (∼150 pg mg protein−1, n=12) and was predominantly expressed by mast cells. A gradual increase in N-acetyl-β-D-glucosaminidase (NAG) activity (maximal at 28 days) was also measured. An antiserum against MIP-1α did not modify the inflammatory response measured at day 7 (except for a 50% reduction in MIP-1α levels), but provoked a significant increase in MPO, NAG and MCP-1 levels as measured at day 21 (n=6, Pvalues (n=8, P<0.05). In conclusion, we have shown that CO/CFA initiates a complex inflammatory reaction in which initial expression of MIP-1α serves a protective role whereas delayed expression of MCP-1 seems to have a genuine pro-inflammatory role. PMID:11704636

7 CFR 1942.308 - Regional Commission grants.

Science.gov (United States)

2010-01-01

...) PROGRAM REGULATIONS (CONTINUED) ASSOCIATIONS Rural Business Enterprise Grants and Television Demonstration... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... Project Management Agreement between the Agency and ARC is not needed for each ARC grant. (d) Other...

Powder agglomeration in a microgravity environment

Science.gov (United States)

Cawley, James D.

1994-01-01

This is the final report for NASA Grant NAG3-755 entitled 'Powder Agglomeration in a Microgravity Environment.' The research program included both two types of numerical models and two types of experiments. The numerical modeling included the use of Monte Carlo type simulations of agglomerate growth including hydrodynamic screening and molecular dynamics type simulations of the rearrangement of particles within an agglomerate under a gravitational field. Experiments included direct observation of the agglomeration of submicron alumina and indirect observation, using small angle light scattering, of the agglomeration of colloidal silica and aluminum monohydroxide. In the former class of experiments, the powders were constrained to move on a two-dimensional surface oriented to minimize the effect of gravity. In the latter, some experiments involved mixture of suspensions containing particles of opposite charge which resulted in agglomeration on a very short time scale relative to settling under gravity.

Patenting Nanomedicines Legal Aspects, Intellectual Property and Grant Opportunities

CERN Document Server

Souto, Eliana B

2012-01-01

"Patenting Nanomedicines: Legal Aspects, Intellectual Property and Grant Opportunities" focuses on the fundamental aspects of Patenting Nanomedicines applied in different "Drug Delivery and Targeting Systems". The promoters of new findings in this field of research are numerous and spread worldwide; therefore, managing intellectual property portfolios, and the acquisition and exploitation of new knowledge face several contingency factors. Today, the scientific community is discussing issues of economic outcomes in the field of Nanomedicines. Major concerns include questions

38 CFR 61.12 - Threshold requirements for capital grant applications.

Science.gov (United States)

2010-07-01

... for capital grant applications. 61.12 Section 61.12 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.12 Threshold requirements for capital grant applications. To be eligible for a capital grant, an applicant must meet the...

76 FR 52340 - Additional Waiver Granted for the State of New York's CDBG Disaster Recovery Grants-The Drawing...

Science.gov (United States)

2011-08-22

... for the State of New York's CDBG Disaster Recovery Grants--The Drawing Center AGENCY: Office of the... amount not to exceed $2,000,000, by The Drawing Center, a Lower Manhattan-based nonprofit organization... Grant Disaster Recovery Program. When the space adjacent to The Drawing Center's existing facility...

32 CFR 22.215 - Distinguishing grants and cooperative agreements.

Science.gov (United States)

2010-07-01

... GRANT AND AGREEMENT REGULATIONS DoD GRANTS AND AGREEMENTS-AWARD AND ADMINISTRATION Selecting the... than an absolute, concept, and that it is primarily based on programmatic factors, rather than requirements for grant or cooperative agreement award or administration. For example, substantial involvement...

The pediatric diabetes consortium: improving care of children with type 1 diabetes through collaborative research.

Science.gov (United States)

2010-09-01

Although there are some interactions between the major pediatric diabetes programs in the United States, there has been no formal, independent structure for collaboration, the sharing of information, and the development of joint research projects that utilize common outcome measures. To fill this unmet clinical and research need, a consortium of seven pediatric diabetes centers in the United States has formed the Pediatric Diabetes Consortium (PDC) through an unrestricted grant from Novo Nordisk, Inc. (Princeton, NJ). This article describes the organizational structure of the PDC and the design of a study of important clinical outcomes in children and adolescents with new-onset, type 1 diabetes mellitus (T1DM). The outcomes study will describe the changes in A1c levels, the frequency of adverse events (diabetic ketoacidosis/severe hypoglycemia), and the frequency and timing of the "honeymoon" phase in newly diagnosed patients with T1DM over the first 12-24 months of the disease and examine the relationship between these clinical outcomes and demographic, socioeconomic, and treatment factors. This project will also allow the Consortium to develop a cohort of youth with T1DM whose clinical course has been well characterized and who wish to participate in future clinical trials and/or contribute to a repository of biological samples.

26 CFR 53.4945-5 - Grants to organizations.

Science.gov (United States)

2010-04-01

... if the section 170(c)(1) organization satisfies the Commissioner in advance that: (a) Its grant... a specified organization exempt from taxation under section 501(a), a less extensive pregrant...)(4) to a private foundation which is exempt from taxation under section 501(a) for endowment, for the...

VT Historic Preservation Grant

Data.gov (United States)

Vermont Center for Geographic Information — The State-funded Historic Preservation Grant Program helps municipalities and non-profit organizations rehabilitate the historic buildings that are a vital part of...

75 FR 6260 - Notice of Intent To Grant an Exclusive License

Science.gov (United States)

2010-02-08

...Notice is hereby given that the Department of Veterans Affairs, Office of Research and Development, intends to grant to PsychoGenics, Inc., 765 Old Saw Mill River Road, Tarrytown, NY 10591 USA, an exclusive license to practice the following patent application: U.S. Patent Application Serial No. 11/713,156 filed February 28, 2007, entitled ``Pharmacological Treatment of Parkinson's Disease.''

45 CFR 2552.93 - What are grants management requirements?

Science.gov (United States)

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false What are grants management requirements? 2552.93... AND COMMUNITY SERVICE FOSTER GRANDPARENT PROGRAM Application and Fiscal Requirements § 2552.93 What are grants management requirements? What rules govern a sponsor's management of grants? (a) A sponsor...

34 CFR 691.15 - Eligibility to receive a grant.

Science.gov (United States)

2010-07-01

... EDUCATION, DEPARTMENT OF EDUCATION ACADEMIC COMPETITIVENESS GRANT (ACG) AND NATIONAL SCIENCE AND MATHEMATICS ACCESS TO RETAIN TALENT GRANT (NATIONAL SMART GRANT) PROGRAMS Application Procedures § 691.15 Eligibility... on an application under § 691.12, or otherwise self-identifies to the institution, that he or she...

30 CFR 795.5 - Grant application procedures.

Science.gov (United States)

2010-07-01

....5 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR SMALL OPERATOR ASSISTANCE PERMANENT REGULATORY PROGRAM-SMALL OPERATOR ASSISTANCE PROGRAM § 795.5 Grant application procedures. A State intending to administer a Small Operator Assistance Program under a grant from...

Grants to Political Groups in the Spanish Legislative Assemblies

Directory of Open Access Journals (Sweden)

Álvaro González-Juliana Muñoz

2014-06-01

Full Text Available This paper analyzes, from the perspective of Administrative Law, one of the sources of public funding of political parties in Spain: the grants to Political Groups in the Legislative Assemblies. This paper focuses on the study of the legal status of those grants, which have received little attention from the legal literature, despite its importance and despite the fact that they are poorly regulated. In this regard, this paper analyzes the legal nature of those grants and it concludes that they are authentic public subsidies. On the basis of this conclusion, the fundamental aspects of those grants become the subject of the study: the requirements and obligations of Political Groups, the procedure for the award of the grants, the control activity and the refund of the grant. As a result, this analysis makes clear the limits and errors of the meager regulation contained in parliamentary Regulations. Last, but not least, several solutions are proposed, taking the General Subsidies Act as a reference.

Novel Dental Cement to Combat Biofilms and Reduce Acids for Orthodontic Applications to Avoid Enamel Demineralization

Directory of Open Access Journals (Sweden)

Ning Zhang

2016-05-01

Full Text Available Orthodontic treatments often lead to biofilm buildup and white spot lesions due to enamel demineralization. The objectives of this study were to develop a novel bioactive orthodontic cement to prevent white spot lesions, and to determine the effects of cement compositions on biofilm growth and acid production. 2-methacryloyloxyethyl phosphorylcholine (MPC, nanoparticles of silver (NAg, and dimethylaminohexadecyl methacrylate (DMAHDM were incorporated into a resin-modified glass ionomer cement (RMGI. Enamel shear bond strength (SBS was determined. Protein adsorption was determined using a micro bicinchoninic acid method. A dental plaque microcosm biofilm model with human saliva as inoculum was used to investigate metabolic activity, colony-forming units (CFU and lactic acid production. Incorporating 3% of MPC, 1.5% of DMAHDM, and 0.1% of NAg into RMGI, and immersing in distilled water at 37 °C for 30 days, did not decrease the SBS, compared to control (p > 0.1. RMGI with 3% MPC + 1.5% DMAHDM + 0.1% NAg had protein amount that was 1/10 that of control. RMGI with triple agents (MPC + DMAHDM + NAg had much stronger antibacterial property than using a single agent or double agents (p < 0.05. Biofilm CFU on RMGI with triple agents was reduced by more than 3 orders of magnitude, compared to commercial control. Biofilm metabolic activity and acid production were also greatly reduced. In conclusion, adding MPC + DMAHDM + NAg in RMGI substantially inhibited biofilm viability and acid production, without compromising the orthodontic bracket bond strength to enamel. The novel bioactive cement is promising for orthodontic applications to hinder biofilms and plaque buildup and enamel demineralization.

Gymnasts and non-athletes muscle activation and torque production at the ankle joint

Directory of Open Access Journals (Sweden)

Natália Batista Albuquerque Goulart

2014-07-01

Full Text Available http://dx.doi.org/10.5007/1980-0037.2014v16n5p555  Artistic Gymnasts (AG execute specific movements that require substantial movement control and force production at the ankle joint. This high demand might change the neuromechanical properties of the ankle joint muscles in these athletes compared to non-athlete girls (NAG. The aim of this study was to compare muscle activation and torque production at the ankle joint between AG and NAG. Ten AG (11.70 ± 1.06 years of age and 10 NAG (11.70 ± 1.49 years of age participated in the study. Electromyographic  (EMG signals of medial gastrocnemius (MG, soleus (SO and tibialis anterior (TA were obtained simultaneously to the maximal isometric plantarflexion (PFT and dorsiflexion (DFT torques of the dominant limb during a maximal voluntary isometric contraction (MVIC at five different joint angles (20°, 10°, 0°, -10° e -20°. Neuromuscular efficiency was also calculated by the Torque/EMG ratio. AG presented higher PFT (p0.05. In addition, AG showed higher values for plantar flexion neuromuscular efficiency and smaller values of dorsiflexion neuromuscular efficiency compared to the NAG (p<0.01. Higher sports demands of AG determined higher PFT, higher plantar flexor efficiency, smaller DFT but similar activation of MG, SO and TA compared to NAG.

Analysis of the Anticancer Phytochemicals in Andrographis paniculata Nees. under Salinity Stress

Directory of Open Access Journals (Sweden)

Daryush Talei

2013-01-01

Full Text Available Salinity causes the adverse effects in all physiological processes of plants. The present study aimed to investigate the potential of salt stress to enhance the accumulation of the anticancer phytochemicals in Andrographis paniculata accessions. For this purpose, 70-day-old plants were grown in different salinity levels (0.18, 4, 8, 12, and 16 dSm−1 on sand medium. After inducing a period of 30-day salinity stress and before flowering, all plants were harvested and the data on morphological traits, proline content and the three anticancer phytochemicals, including andrographolide (AG, neoandrographolide (NAG, and 14-deoxy-11,12-didehydroandrographolide (DDAG, were measured. The results indicated that salinity had a significant effect on the aforementioned three anticancer phytochemicals. In addition, the salt tolerance index (STI was significantly decreased, while, except for DDAG, the content of proline, the AG, and NAG was significantly increased (P≤0.01. Furthermore, it was revealed that significant differences among accessions could happen based on the total dry weight, STI, AG, and NAG. Finally, we noticed that the salinity at 12 dSm−1 led to the maximum increase in the quantities of AG, NAG, and DDAG. In other words, under salinity stress, the tolerant accessions were capable of accumulating the higher amounts of proline, AG, and NAG than the sensitive accessions.

Analysis of the Anticancer Phytochemicals in Andrographis paniculata Nees. under Salinity Stress

Science.gov (United States)

Valdiani, Alireza; Maziah, Mahmood; Saad, Mohd Said

2013-01-01

Salinity causes the adverse effects in all physiological processes of plants. The present study aimed to investigate the potential of salt stress to enhance the accumulation of the anticancer phytochemicals in Andrographis paniculata accessions. For this purpose, 70-day-old plants were grown in different salinity levels (0.18, 4, 8, 12, and 16 dSm−1) on sand medium. After inducing a period of 30-day salinity stress and before flowering, all plants were harvested and the data on morphological traits, proline content and the three anticancer phytochemicals, including andrographolide (AG), neoandrographolide (NAG), and 14-deoxy-11,12-didehydroandrographolide (DDAG), were measured. The results indicated that salinity had a significant effect on the aforementioned three anticancer phytochemicals. In addition, the salt tolerance index (STI) was significantly decreased, while, except for DDAG, the content of proline, the AG, and NAG was significantly increased (P ≤ 0.01). Furthermore, it was revealed that significant differences among accessions could happen based on the total dry weight, STI, AG, and NAG. Finally, we noticed that the salinity at 12 dSm−1 led to the maximum increase in the quantities of AG, NAG, and DDAG. In other words, under salinity stress, the tolerant accessions were capable of accumulating the higher amounts of proline, AG, and NAG than the sensitive accessions. PMID:24371819

National Geospatial-Intelligence Agency Academic Research Program

Science.gov (United States)

Loomer, S. A.

2004-12-01

"Know the Earth.Show the Way." In fulfillment of its vision, the National Geospatial-Intelligence Agency (NGA) provides geospatial intelligence in all its forms and from whatever source-imagery, imagery intelligence, and geospatial data and information-to ensure the knowledge foundation for planning, decision, and action. To achieve this, NGA conducts a multi-disciplinary program of basic research in geospatial intelligence topics through grants and fellowships to the leading investigators, research universities, and colleges of the nation. This research provides the fundamental science support to NGA's applied and advanced research programs. The major components of the NGA Academic Research Program (NARP) are: - NGA University Research Initiatives (NURI): Three-year basic research grants awarded competitively to the best investigators across the US academic community. Topics are selected to provide the scientific basis for advanced and applied research in NGA core disciplines. - Historically Black College and University - Minority Institution Research Initiatives (HBCU-MI): Two-year basic research grants awarded competitively to the best investigators at Historically Black Colleges and Universities, and Minority Institutions across the US academic community. - Director of Central Intelligence Post-Doctoral Research Fellowships: Fellowships providing access to advanced research in science and technology applicable to the intelligence community's mission. The program provides a pool of researchers to support future intelligence community needs and develops long-term relationships with researchers as they move into career positions. This paper provides information about the NGA Academic Research Program, the projects it supports and how other researchers and institutions can apply for grants under the program.

UCLA accelerator research and development

International Nuclear Information System (INIS)

Cline, D.B.

1992-01-01

This progress report covers work supported by the above DOE grant over the period November 1, 1991 to July 31, 1992. The work is a program of experimental and theoretical studies in advanced particle accelerator research and development for high energy physics applications. The program features research at particle beam facilities in the United States and includes research on novel high power sources, novel focussing systems (e.g. plasma lens), beam monitors, novel high brightness, high current gun systems, and novel flavor factories in particular the φ Factory

24 CFR 941.612 - Disbursement of grant funds.

Science.gov (United States)

2010-04-01

... following requirements: (1) Front-end assistance may be used to pay for materials and services related to... Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN HOUSING, DEPARTMENT OF HOUSING AND... Development of Public Housing Units § 941.612 Disbursement of grant funds. (a) Front-end drawdowns. A PHA may...

Increased urinary cadmium excretion and its relationship to urinary N-acetyl-[beta]-D-glucosaminidase activity in smokers

Energy Technology Data Exchange (ETDEWEB)

Koyama, Hiroshi; Satoh, Hiroshi (Tohoku Univ. School of Medicine, Dept. of Environmental Health Sciences, Sendai (Japan)); Suzuki, Shosuke (Gunma Univ. School of Medicine, Dept. of Public Health, Maebashi (Japan)); Tohyama, Chiharu (National Institute of Environmental Studies, Environmental Health Sciences Div., Tsukuba (Japan))

1992-10-01

To assess the renal effects of low-level exposure to cadmium due to smoking we examined blood and urinary levels of cadmium and urinary excretions of N-acetyl-[beta]-D-glucosaminidase (NAG), [beta][sub 2]-microglobulin (BMG) and metallothionein in 94 male workers aged 18-55 years. Both blood and urinary cadmium levels indicated excess exposure to cadmium caused by smoking. The urinary cadmium concentration ranged between 0.1 and 5.0 [mu]g/g creatinine and increased significantly with age in the smokers. Neither urinary NAG nor BMG was increased in the smokers compared from non-smokers. A positive relationship between urinary cadmium and metallothionein was obtained not only in the smokers but also in the non-smokers. Furthermore, in the smokers urinary cadmium and metallothionein was positively related with urinary NAG. Since NAG in urine mostly originates from tubular cells by lysosomal exocytosis, the results may reflect an early cadmium effect on the lysosomal functions. Inhibitory effect of cadmium on the lysosomal degradation activities was discussed as a possible explanation of the positive relationship of urinary cadmium and metallothionein to urinary NAG. (orig.).

Improving University Research Value

Directory of Open Access Journals (Sweden)

Kelley O’Reilly

2012-07-01

Full Text Available This article investigates the current data management practices of university researchers at an Intermountain West land-grant research university in the United States. Key findings suggest that researchers are primarily focused on the collection and housing of research data. However, additional research value exists within the other life cycle stages for research data—specifically in the stages of delivery and maintenance. These stages are where most new demands and requirements exist for data management plans and policies that are conditional for external grant funding; therefore, these findings expose a “gap” in current research practice. These findings should be of interest to academics and practitioners alike as findings highlight key management gaps in the life cycle of research data. This study also suggests a course of action for academic institutions to coalesce campus-wide assets to assist researchers in improving research value.

45 CFR 2551.93 - What are grants management requirements?

Science.gov (United States)

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false What are grants management requirements? 2551.93... AND COMMUNITY SERVICE SENIOR COMPANION PROGRAM Application and Fiscal Requirements § 2551.93 What are grants management requirements? What rules govern a sponsor's management of grants? (a) A sponsor shall...

45 CFR 2553.73 - What are grants management requirements?

Science.gov (United States)

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false What are grants management requirements? 2553.73 Section 2553.73 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL... § 2553.73 What are grants management requirements? What rules govern a sponsor's management of grants? (a...

38 CFR 61.14 - Selecting applications for capital grants.

Science.gov (United States)

2010-07-01

... for capital grants. 61.14 Section 61.14 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.14 Selecting applications for capital grants. (a) Applicants will first be grouped in categories according to the funding priorities set...

50 CFR 85.30 - Grant selection criteria.

Science.gov (United States)

2010-10-01

... (CONTINUED) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM CLEAN VESSEL ACT GRANT PROGRAM Grant...; (e) Proposals for innovative ways to increase the availability and use of pumpout and dump stations, e.g., where private parties put in more than the minimum amount; (f) Proposals that include an...

25 CFR 1000.53 - Can Tribes/Consortia that receive advance planning grants also apply for a negotiation grant?

Science.gov (United States)

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Can Tribes/Consortia that receive advance planning grants also apply for a negotiation grant? 1000.53 Section 1000.53 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN...

Grant Writing Skill Building: A Business Administration Curriculum Proposal

Science.gov (United States)

Blankenship, Dianna; Jones, Irma; Lovett, Marvin

2010-01-01

This paper reviews the need for grant writing skills within various types of organizations and the resulting proposal for including grant writing within business administration curriculum at the undergraduate and/or graduate levels. An introduction precedes the results of a survey regarding current grant writing courses within AACSB schools of…

15 CFR 917.11 - Guidelines for Sea Grant Fellowships.

Science.gov (United States)

2010-01-01

... percent matching funds from non-Federal sources to which all Matched Funding Program projects are subject... NATIONAL SEA GRANT PROGRAM FUNDING REGULATIONS Sea Grant Matched Funding Program § 917.11 Guidelines for... applications for Sea Grant Fellowship funding. (b) Funding will be made to eligible entities (see § 917.10 of...

77 FR 54917 - Findings of Research Misconduct

Science.gov (United States)

2012-09-06

... monkeys were able to understand communicative gestures performed by a human. Specifically, (1) in the... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Findings of Research Misconduct... RR003640-13, National Institute on Deafness and Other Communication Disorders (NIDCD), NIH, grant 5 R01...