WorldWideScience

Sample records for repo petsa stavroula

  1. Transmedia storytelling and the new era of media convergence in higher education, by Stavroula Kalogeras

    Directory of Open Access Journals (Sweden)

    Katherine E. Morrissey

    2015-09-01

    Full Text Available Stavroula Kalogeras. Transmedia Storytelling and the New Era of Media Convergence in Higher Education. New York: Palgrave Macmillan, 2014, hardcover, $100 (276p ISBN 978-1137388360.

  2. OPINION Is the repo a derivative?

    African Journals Online (AJOL)

    Introduction. The literature on the derivative markets and the spot (cash) financial markets ... value of R9 450 000, and the interest factor for the period of the repo is R35 000 ... mathematics is simple and in the case of bonds a little less simple.

  3. RepoSTAR. A Code package for control and evaluation of statistical calculations with the program package RepoTREND; RepoSTAR. Ein Codepaket zur Steuerung und Auswertung statistischer Rechenlaeufe mit dem Programmpaket RepoTREND

    Energy Technology Data Exchange (ETDEWEB)

    Becker, Dirk-Alexander

    2016-05-15

    The program package RepoTREND for the integrated long terms safety analysis of final repositories allows besides deterministic studies of defined problems also statistical or probabilistic analyses. Probabilistic uncertainty and sensitivity analyses are realized in the program package repoTREND by a specific statistic frame called RepoSTAR. The report covers the following issues: concept, sampling and data supply of single simulations, evaluation of statistical calculations with the program RepoSUN.

  4. Repos, fire sales, and bankruptcy policy

    OpenAIRE

    Antinolfi, Gaetano; Carapella, Francesca; Kahn, Charles; Martin, Antoine; Mills, David; Nosal, Ed

    2012-01-01

    The events from the 2007-2009 financial crisis have raised concerns that the failure of large financial institutions can lead to destabilizing fire sales of assets. The risk of fire sales is related to exemptions from bankruptcy's automatic stay provision enjoyed by a number of financial contracts, such as repo. An automatic stay prohibits collection actions by creditors against a bankrupt debtor or his property. It prevents a creditor from liquidating collateral of a defaulting debtor since ...

  5. PFLOTRAN-RepoTREND Source Term Comparison Summary.

    Energy Technology Data Exchange (ETDEWEB)

    Frederick, Jennifer M

    2018-03-01

    Code inter-comparison studies are useful exercises to verify and benchmark independently developed software to ensure proper function, especially when the software is used to model high-consequence systems which cannot be physically tested in a fully representative environment. This summary describes the results of the first portion of the code inter-comparison between PFLOTRAN and RepoTREND, which compares the radionuclide source term used in a typical performance assessment.

  6. Repo auction formats, bidders' behaviour and money market response in India

    OpenAIRE

    Singh, Bhupal; Dhal, Sarat C.

    1998-01-01

    The treasury securities repo-auction is an important instrument for central banks in managing liquidity and sending interest rate signal to the money market. In the Indian context, the repo-auctions have been used actively in the post-reform period. The present study illustrates the money market reaction to repo-auctions and points out whether such reaction is consistent with applied auction rules. The policy implications are analysed in the light of alternative rules pertaining to discrimina...

  7. CONSIDERATIONS REGARDING THE SPECIFIC ELEMENTS OF THE REPURCHASE AGREEMENT (REPO

    Directory of Open Access Journals (Sweden)

    Bujorel Florea

    2014-11-01

    Full Text Available The current article focuses on the specific elements of the repurchase agreement, as they are regulated in the new Civil Code (Law no. 287/2009. In the beginning the author makes a general characterization of this type of contract, from the perspective of the specific elements regarding the contracting parties, the object of the contract and the moment of fulfilling certain obligations assumed by the parties. Then, the study defines the notions of “repo” and “reverse repo” and differentiates the repurchase agreement (repo from other similar contracts, configuring thus more clearly the analyzed convention. A specific element of the contract is represented by its legal nature of sui-generis contract, which the author explains by the fact that in the doctrine there is no unanimous opinion concerning this aspect. At the same time, the specificity of the repo is highlighted by presenting its main effects: the double transfer of property, the transmission of the accessory rights, the original buyer’s obligation to exercise his option, and the original seller’s obligations to make available for the original buyer the funds necessary for exercising the right of option and for making the payment. Last but not least, the specificity of this type of contract is revealed through reflecting the differences between the liquidation, prorogation and renewal of the debated convention. The study presents the viewpoints expressed in the literature, as well as the author’s opinions as regards the controversial legal problems in the studied field.

  8. Šveitsi firma plaanib investeerida Repo Vabrikutesse 200 miljonit krooni / Gerli Romanovitsh

    Index Scriptorium Estoniae

    Romanovitš, Gerli, 1977-

    2005-01-01

    Ilmunud ka: Severnoje Poberezhje 1. sept. lk 1,3. AS-i Repo Vabrikud omanik, Šveitsi investeerimisfirma Sorbes AG, kellele kuulus 51% ettevõtte aktsiatest, ostis SEB Eesti Ühispangalt ka ülejäänud aktsiad ning plaanib ainuomanikuna investeerida puitplaaditööstusesse 200 miljonit krooni

  9. eRepo-ORP: Exploring the Opportunity Space to Combat Orphan Diseases with Existing Drugs.

    Science.gov (United States)

    Brylinski, Michal; Naderi, Misagh; Govindaraj, Rajiv Gandhi; Lemoine, Jeffrey

    2017-12-10

    About 7000 rare, or orphan, diseases affect more than 350 million people worldwide. Although these conditions collectively pose significant health care problems, drug companies seldom develop drugs for orphan diseases due to extremely limited individual markets. Consequently, developing new treatments for often life-threatening orphan diseases is primarily contingent on financial incentives from governments, special research grants, and private philanthropy. Computer-aided drug repositioning is a cheaper and faster alternative to traditional drug discovery offering a promising venue for orphan drug research. Here, we present eRepo-ORP, a comprehensive resource constructed by a large-scale repositioning of existing drugs to orphan diseases with a collection of structural bioinformatics tools, including eThread, eFindSite, and eMatchSite. Specifically, a systematic exploration of 320,856 possible links between known drugs in DrugBank and orphan proteins obtained from Orphanet reveals as many as 18,145 candidates for repurposing. In order to illustrate how potential therapeutics for rare diseases can be identified with eRepo-ORP, we discuss the repositioning of a kinase inhibitor for Ras-associated autoimmune leukoproliferative disease. The eRepo-ORP data set is available through the Open Science Framework at https://osf.io/qdjup/. Copyright © 2017. Published by Elsevier Ltd.

  10. RepoTREND. The program package for the integrated long term safety analysis of final repository systems. Version 4.5 (State March 2016); RepoTREND. Das Programmpaket zur integrierten Langzeitsicherheitsanalyse von Endlagersystemen. Version 4.5 (Stand Maerz 2016)

    Energy Technology Data Exchange (ETDEWEB)

    Reiche, Tatiana

    2016-04-15

    The long-term safety analysis is the analysis of final repository behavior after closure includes the spreading of pollutants into the biosphere (mobilization and release of pollutants into the near field, radionuclide migration through the geosphere, radiation exposure in the biosphere) and the radiological consequences. The report describes the program package RepoTREND, the respective modules (near field, GeoTREND, BioTREND and probabilistic analyses), sequencing and postprocessing and the quality management.

  11. Different Levels of Expression of the Clock Protein PER and the Glial Marker REPO in Ensheathing and Astrocyte-Like Glia of the Distal Medulla of Drosophila Optic Lobe.

    Science.gov (United States)

    Krzeptowski, Wojciech; Walkowicz, Lucyna; Płonczyńska, Alicja; Górska-Andrzejak, Jolanta

    2018-01-01

    Circadian plasticity of the visual system of Drosophila melanogaster depends on functioning of both the neuronal and glial oscillators. The clock function of the former is already quite well-recognized. The latter, however, is much less known and documented. In this study we focus on the glial oscillators that reside in the distal part of the second visual neuropil, medulla (dMnGl), in vicinity of the PIGMENT-DISPERSING FACTOR (PDF) releasing terminals of the circadian clock ventral Lateral Neurons (LNvs). We reveal the heterogeneity of the dMnGl, which express the clock protein PERIOD (PER) and the pan-glial marker REVERSED POLARITY (REPO) at higher (P1) or lower (P2) levels. We show that the cells with stronger expression of PER display also stronger expression of REPO, and that the number of REPO-P1 cells is bigger during the day than during the night. Using a combination of genetic markers and immunofluorescent labeling with anti PER and REPO Abs, we have established that the P1 and P2 cells can be associated with two different types of the dMnGl, the ensheathing (EnGl), and the astrocyte-like glia (ALGl). Surprisingly, the EnGl belong to the P1 cells, whereas the ALGl, previously reported to play the main role in the circadian rhythms, display the characteristics of the P2 cells (express very low level of PER and low level of REPO). Next to the EnGl and ALGl we have also observed another type of cells in the distal medulla that express PER and REPO, although at very low levels. Based on their morphology we have identified them as the T1 interneurons. Our study reveals the complexity of the distal medulla circadian network, which appears to consist of different types of glial and neuronal peripheral clocks, displaying molecular oscillations of higher (EnGl) and lower (ALGl and T1) amplitudes.

  12. Macroprudential Regulation Under Repo Funding

    OpenAIRE

    Laura Valderrama

    2010-01-01

    The use of collateral has become one of the most widespread risk mitigation techniques. While it brings stabilizing effects to the individual lender we argue that it may exacerbate systemic risk through margin call activation. We show how a liquidity shock to the cash lender may propagate as a solvency shock via liquidity hoarding even if the cash lender remains solvent in all states of nature. Albeit a cost-effective response of the cash lender to a liquidity shock, liquidity hoarding may le...

  13. Comparaison de deux mode de préparation des médicaments dans une maison de repos et de soins en Communauté germanophone : impact quantitatif et qualitatif sur la pharmacothérapie

    OpenAIRE

    Schroeder, Béatrice

    2010-01-01

    Introduction : La préparation des semainiers pour les patients des maisons de repos et de soins (MRS) par le pharmacien d’officine permet de diminuer les erreurs liées à l’administration des médicaments. Outre ce bénéfice, l’accès pour le pharmacien à l’ensemble du traitement devrait faciliter la validation pharmaceutique des prescriptions et le développement des soins pharmaceutiques de qualité pour les patients résidants en communauté. Contexte de l’étude : La MRS étudiée est une instit...

  14. info:eu-repo/semantics/publishedVersion

    OpenAIRE

    Leyton Donoso, Fabiola

    2008-01-01

    La crisis medio ambiental por la que atraviesa el planeta no es noticia nueva. Menos aún cuando esta crisis asume un carácter y unas consecuencias multiformes y globales que nos preocupan a todos: la explosión demográfica, el calentamiento global producto del efecto invernadero, la depredación de los llamados "recursos naturales", la contaminación de aguas, aire y tierra; la acelerada extinción de especies animales y vegetales, la sostenida deforestación y desertificación,etc. Este diagnóstic...

  15. The requirement for a „new public” in EU copyright law / Stavroula Karapapa

    Index Scriptorium Estoniae

    Karapapa, Stavroula

    2017-01-01

    Üldsusele edastamise kontseptsioonist ELi autoriõiguses, juurdepääsust autoriõigusega kaitstud töödele (hüperlingid) ning autoriõiguste rikkumisega seotud Euroopa Kohtu praktikast (nt lahend C-466/12)

  16. REPO Operations - a Way to Adjust Liquidity Crisis on Banking Institutions

    Directory of Open Access Journals (Sweden)

    Lucean Mihalcea

    2016-07-01

    Full Text Available Money market operations (open market operations constitute the most important instrument of the monetary policy of the NATIONAL BANK of ROMANIA. They shall be carried out on the initiative of the Central Bank, having the following functions: guiding interest rates, managing the liquidity conditions of the monetary market and signaling the orientation of the monetary policy. In this context, a systematic and a market organization is essential able to adapt to the new conditions imposed by the relaxation of credit operations. Implementation and operational systematization of such types of transaction can help banking entities in adjusting the liquidity crisis and the support on the way to economic growth.

  17. Des liens à opérer entre le travail, le mariage et le repos. Courbet illustrateur de Proudhon

    OpenAIRE

    Pasteur , Sébastien

    2008-01-01

    National audience; L'amitié et la coopération entre Courbet et Proudhon ont donné lieu à la rédaction de l'ouvrage posthume, Du principe de l'art et de sa destination sociale, à la lumière d'autres ouvrages de Proudhon, principalement De la célébration du dimanche, nous verrons comment la peinture de Courbet illustre la pensée du philosophe Franc-Comtois.

  18. A VAR Analysis of Kenya’s Monetary Policy Transmission Mechanism; How Does the Central Bank’s REPO Rate Affect the Economy?

    OpenAIRE

    Kevin C Cheng

    2006-01-01

    This paper examines the impact of a monetary policy shock on output, prices, and the nominal effective exchange rate for Kenya using data during 1997–2005. Based on techniques commonly used in the vector autoregression literature, the main results suggest that an exogenous increase in the short-term interest rate tends to be followed by a decline in prices and appreciation in the nominal exchange rate, but has insignificant impact on output. Moreover, the paper finds that variations in the sh...

  19. Added mass induced by an uncompressible ideal and still fluid on a structure a bibliography; Prise en compte d`un fluide parfait incompressible au repos comme masse ajoutee sur une structure. Synthese bibliographique

    Energy Technology Data Exchange (ETDEWEB)

    Rousseau, G.

    1994-02-01

    We first recall the most important definitions about the fluid/structure interaction. We also define some non-dimensional numbers in order to analyze the physical effects in the fluid we have to take into account: viscosity, compressibility, gravity, inertial effect. Then, in the first part called ``Calculation of the added mass: Models``, we explain the equations which allow us to find the added mass on one structure. After that, we deal with the dynamical behaviour of tube bundles immersed in a fluid. We present a two dimensional modelling. Therefore, the fluid structure interaction only takes place in the planes perpendicular to the tube axis. The added mass matrix of the fluid on the whole tubes is built for every kind of cross-section. But we also focus our attention on the special case of circular cross-section. Lastly, when the number of the tubes in the bundle is huge, the direct calculation of the global added mass matrix is impossible: we must use a method of homogenization to describe the global dynamical behaviour of the tube bundles. In particular, the eigenfrequencies of such homogenized medium are determined. We especially focus our attention on the square nuclear fuel bundles immersed in a confined fluid. In the second part called ``Numerical methods used for the fluid structure interaction``, we first tackle the integral methods. However, in these methods, some theoretical and numerical difficulties arise and this fact makes the advantage of a little number of degrees of freedom far less interesting. This leads us to consider the finite element methods. It allows us to determine the added mass matrix of the fluid on the structure expressed with the nodal interpolation functions used by the FE methods. We then propose a discretization of the equations of the movement of tube bundles immersed in a fluid, with or without homogenization. At last, we compare the efficiency of the integral methods to the FE methods. (author). figs., tabs., 54 refs.

  20. 76 FR 54824 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Approving Proposed Rule...

    Science.gov (United States)

    2011-09-02

    ... risk management measures with respect to the GCF Repo service. First, FICC imposed a collateral premium.../DTCC. \\4\\ The main purpose of the TPR is to develop recommendations to address the risk presented by.... The TPR has mandated that the collateral used in tri-party repo and GCF Repo transactions be ``locked...

  1. Setting up the photoluminescence laboratory at ISOLDE & Perturbed Angular Correlation spectroscopy for BIO physics experiments using radioactive ions

    CERN Document Server

    Savva, Giannis

    2016-01-01

    The proposed project I was assigned was to set up the photoluminescence (PL) laboratory at ISOLDE, under the supervision of Karl Johnston. My first week at CERN coincided with the run of a BIO physics experiment using radioactive Hg(II) ions in which I also participated under the supervision of Stavroula Pallada. This gave me the opportunity to work in two projects during my stay at CERN and in the present report I describe briefly my contribution to them.

  2. Effect of Different Manufacturing Methods on the Conflict between Porosity and Mechanical Properties of Spiral and Porous Polyethylene Terephthalate/Sodium Alginate Bone Scaffolds

    Directory of Open Access Journals (Sweden)

    Ching-Wen Lou

    2015-12-01

    Full Text Available In order to solve the incompatibility between high porosity and mechanical properties, this study fabricates bone scaffolds by combining braids and sodium alginate (SA membranes. Polyethylene terephthalate (PET plied yarns are braided into hollow, porous three dimensional (3D PET braids, which are then immersed in SA solution, followed by cross-linking with calcium chloride (CaCl2 and drying, to form PET bone scaffolds. Next, SA membranes are rolled and then inserted into the braids to form the spiral and porous PET/SA bone scaffolds. Samples are finally evaluated for surface observation, porosity, water contact angle, compressive strength, and MTT assay. The test results show that the PET bone scaffolds and PET/SA bone scaffolds both have good hydrophilicity. An increasing number of layers and an increasing CaCl2 concentration cause the messy, loose surface structure to become neat and compact, which, in turn, decreases the porosity and increases the compressive strength. The MTT assay results show that the cell viability of differing SA membranes is beyond 100%, indicating that the PET/SA bone scaffolds containing SA membranes are biocompatible for cell attachment and proliferation.

  3. Discounting with Imperfect Collateral

    OpenAIRE

    Lou, Wujiang

    2017-01-01

    Cash collateral is perfect in that it provides simultaneous counterparty credit risk protection and derivatives funding. Securities are imperfect collateral, because of collateral segregation or differences in CSA haircuts and repo haircuts. Moreover, the collateral rate term structure is not observable in the repo market, for derivatives netting sets are perpetual while repo tenors are typically in months. This article synthesizes these effects into a derivative financing rate that replaces ...

  4. 77 FR 48572 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Approving Proposed Rule...

    Science.gov (United States)

    2012-08-14

    ... collateral repos, based on rate and term, throughout the day with inter-dealer broker netting members on a... issues arose from the inter-bank funds settlements related to the service, namely, the large interbank... equivalent value can be accomplished by simple debits and credits to the accounts of the GCF Repo dealer...

  5. Mezcal Animations

    DEFF Research Database (Denmark)

    Screening of a fixed-media audio-visual composition ('visual music'), presentation of a talk, and a group performance as Repo-Jazz.......Screening of a fixed-media audio-visual composition ('visual music'), presentation of a talk, and a group performance as Repo-Jazz....

  6. Stability of erythropoietin repackaging in polypropylene syringes for clinical use

    Directory of Open Access Journals (Sweden)

    Angela Marsili

    2017-02-01

    Full Text Available Introduction: Epoetin alfa (Eprex® is a subcutaneous, injectable formulation of short half-life recombinant human erythropoietin (rHuEPO. To current knowledge there are no published studies regarding the stability of rHuEPO once repackaging occurs (r-EPO for clinical trial purposes. Materials and methods: We assessed EPO concentration in Eprex® and r-EPO syringes at 0, 60, 90, and 120 days after repackaging in polypropylene syringes. R-EPO was administered to 56 patients taking part in a clinical trial in Friedreich Ataxia. Serum EPO levels were measured at baseline and 48 h after r-EPO administration. Results: No differences were found between r-EPO and Eprex® syringes, but both globally decreased in total EPO content during storage at 4 °C. Patients receiving r-EPO had similar levels in EPO content as expected from previous trials in Friedreich Ataxia and from pharmacokinetics studies in healthy volunteers. Discussion: We demonstrate that repackaging of EPO does not alter its concentration if compared to the original product (Eprex®. This is true both for repackaging procedures and for the stability in polypropylene tubes. The expiration date of r-EPO can be extended from 1 to 4 months after repackaging, in accordance with pharmacopeia rules.

  7. Evaluation of the ticketing aggressive cars and trucks (TACT) program in Pennsylvania (071408).

    Science.gov (United States)

    2009-08-14

    The Pennsylvania State Police and Pennsylvania Department of Transportation implemented the "Ticketing Aggressive Cars and Trucks (TACT)" media and enforcement initiative on a portion of Interstate 81 in southern Pennsylvania, in late 2008. This repo...

  8. "Kadriorg" dozhivajet poslednije dni / Urmas Tooming

    Index Scriptorium Estoniae

    Tooming, Urmas

    2008-01-01

    Voldemar Herkeli projekteeritud Kadrioru kohvik Tallinnas lammutatakse. Asemele ehitatakse Enn Rajasaare (arhitektuuribüroo JVR) projekteeritud külaliskorteritega ärimaja. Kohvikuhoone taga asuv ajalooline villa Mon Repos tuleb arendajal säilitada. Robert Nermani kommentaar

  9. 2018-05-23T15:15:42Z https://www.ajol.info/index.php/all/oai oai:ojs ...

    African Journals Online (AJOL)

    Ubiquitin which has the function of selective protein degradation may play an important ... mitochondrion, cell skeleton and plasma membrane occupied about 47.80, 26.10, ... info:eu-repo/semantics/publishedVersion Peer-reviewed Article ...

  10. 2018-06-05T03:48:58Z https://www.ajol.info/index.php/all/oai oai:ojs ...

    African Journals Online (AJOL)

    A membrane-bound protein with N-methyltransferase activity, associated with ... metabolism, has been isolated from purified human blood platelet plasma membranes. ... info:eu-repo/semantics/publishedVersion Peer-reviewed Article ...

  11. AcEST: BP917893 [AcEST

    Lifescience Database Archive (English)

    Full Text Available Prot (No blast op. Sequence too short.) sp_hit_id - Definition - Align length - Score (bit) - E-value - Repo...too short.) tr_hit_id - Definition - Align length - Score (bit) - E-value - Report - ...

  12. AcEST: BP917876 [AcEST

    Lifescience Database Archive (English)

    Full Text Available Prot (No blast op. Sequence too short.) sp_hit_id - Definition - Align length - Score (bit) - E-value - Repo...too short.) tr_hit_id - Definition - Align length - Score (bit) - E-value - Report - ...

  13. На стройке "Черного лебедя" затишье

    Index Scriptorium Estoniae

    2009-01-01

    Tallinnas Kadriorus asuv 19. sajandist pärinev arhitektuurimälestis puitvilla Mon Repos laguneb. Hoone peab taastama firma NG Eesti. Lammutatud restoranihoone "Must Luik" kohale kavandatud Enn Rajasaare projekteeritud hoonet pole veel ehitama hakatud

  14. Must Luik tõuseb varjusurmast / Urmas Tooming

    Index Scriptorium Estoniae

    Tooming, Urmas, 1954-

    2010-01-01

    Tallinnasse Kadriorgu endise Musta Luige kohviku kinnistule ehitatakse Enn Rajasaare (JVR Arhitektuuribüroo) projekteeritud elu- ja ärihoone, mis valmib 2011. aasta suveks. Restaureerimisfirma Kuukaar taastab kõrvalkrundil asuva villa Mon Repos

  15. Kadrioru kuulus Must Luik elab oma viimaseid päevi / Urmas Tooming

    Index Scriptorium Estoniae

    Tooming, Urmas

    2008-01-01

    Voldemar Herkeli projekteeritud Kadrioru kohvik Tallinnas lammutatakse. Asemele ehitatakse Enn Rajasaare (arhitektuuribüroo JVR) projekteeritud külaliskorteritega ärimaja. Kohvikuhoone taga asuv ajalooline villa Mon Repos tuleb arendajal säilitada. Robert Nermani kommentaar

  16. Вилла в Кадриорге разрушается / Уве Гнадентейх

    Index Scriptorium Estoniae

    Гнадентайх, Уве

    2009-01-01

    Tallinnas Kadriorus asuv puitvilla Mon Repos laguneb, kuna arendaja NG Eesti ei ole teinud hädavajalikke konserveerimistöid. 19. sajandist pärit arhitektuurimälestise omanikke on keeruline korrale kutsuda

  17. 2018-04-21T19:46:15Z https://www.ajol.info/index.php/index/oai oai ...

    African Journals Online (AJOL)

    Cannabis was the most abused drug in 2002-2007 (53.5%) as compared to cocaine (44%) in 1992–1997 (c2 35.5, p West African College of Physicians and the West African College of Surgeons 2010-06-29 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf ...

  18. Interest Rate Pass-through in Sri Lanka

    OpenAIRE

    Amarasekara, Chandranath

    2005-01-01

    The Central Bank of Sri Lanka has increasingly been relying on interest rates as the instrument for conducting monetary policy. Changes to the key monetary policy variables, the Repo and the Reverse Repo rates, are initially expected to be reflected in the OMO rates and the call money market rates, before being passedthrough to commercial bank retail interest rates. It is important to obtain a good understanding of the speed and magnitude of the interest rate pass-through to make timely monet...

  19. Recombinant erythropoietin and analogues: a challenge for doping control.

    Science.gov (United States)

    Pascual, J A; Belalcazar, V; de Bolos, C; Gutiérrez, R; Llop, E; Segura, J

    2004-04-01

    Erythropoietin (EPO) increases the number of circulating erythrocytes and thus muscle oxygenation. The availability of the recombinant protein (rEPO) has increased the risk of its illegal use in sports, its detection being a difficult challenge. Five different hematopoietic parameters were initially chosen as indirect markers of rEPO abuse: concentration of serum EPO, concentration of serum-soluble transferrin receptors (sTFr), hematocrit, percentage of reticulocytes, and percentage of macrocytes. New models considering only hemoglobin, serum EPO concentration, and percentage of reticulocytes are simpler and seem to be more sensitive when low doses of rEPO are used. A more direct method of urine analysis (isoelectrofocusing, double blotting, and chemiluminescent detection) based on the charge differences between rEPO and endogenous EPO, related to their carbohydrate composition, provides proof of rEPO use. Furthermore, this approach permits the detection of darbepoetin, a direct analogue of EPO also known as NESP ("new erythropoiesis stimulating protein"). Recently a protein conjugate, "synthetic erythropoiesis protein" (SEP), containing precision-length, monodisperse, negatively charged polymers instead of oligosaccharides has been synthesized. Finally, EPO-mimetics are molecules capable of acting as EPO in dimerizing the EPO receptor. Two kinds of EPO-mimetics have been described: peptides and nonpeptides. The enhancement of oxygen availability to muscles by rEPO, analogues, and mimetics constitutes one of the main challenges to doping control. Major steps have already been developed for detection ofrEPO and some analogues. In the near future, the transfection to an athlete's body of genes that code for erythropoietin might be an emerging doping issue, and sports authorities have incorporated "gene doping" among the prohibited practices.

  20. CLINICAL APPLICATION OF RECOMBINANT ERYTHROPOIETIN IN BETA-THALASSAEMIA INTERMEDIA.

    Science.gov (United States)

    Asadov, Ch; Alimirzoyeva, Z; Hasanova, M; Mammadova, T; Shirinova, A

    2016-06-01

    Research objective is to study the efficacy of recombinant erythropoietin (epoetin alfa) as alternative method of treatment beta-thalassemia intermedia. Study involved 58 patients with beta-thalassemia intermedia (23 women and 35 men). In all observed patients was defined levels of hemoglobin (Hb), red blood cells (RBC), erythrocyte indexes (MCV, MCH, MCHC), hemoglobin fractions (HbA, HbA2, HbF), serum ferritin, serum erythropoietin before and after administrated rEPO. All patients received rEPO during 6 month at the dose - 10000 IU subcutaneously. The majority of patients - 39 (67%) had a good response to rEPO (increase in hemoglobin level more than 20 g/l); 16 patients (28%) had a mean response (increase in Hb 10 - 20 g/l); in 3 (5%) patients occurred poor response to rEPO therapy (increase in Hb intermedia patients there was a statistically significant change in the number of RBC, levels of HbF and sEPO. The evaluation of interdependence between the indices of the baseline sEPO and increased Hb values in patients after rEPO treatment revealed the presence of the reverse direct relationship (r=-0.67). Based on the results, it can be concluded that the use of rEPO in complex therapy of beta-thalassemia intermedia leads to increased levels of Hb and consequently reducing the need for blood transfusions, and accordingly expected to prevent severe complications of blood transfusion (alloimmunization, hypersplenism, iron overload, contamination transmissible infections) facilitating normal growth and development, and a better quality of life.

  1. An intrathermocline eddy and a tropical cyclone in the Bay of Bengal

    Digital Repository Service at National Institute of Oceanography (India)

    Gordon, A.L.; Shroyer, E.; Murty, V.S.N.

    RepoRts | 7:46218 | DOI: 10.1038/srep46218 www.nature.com/scientificreports An Intrathermocline Eddy and a tropical cyclone in the Bay of Bengal Arnold L. Gordon1, Emily Shroyer2 & V. S. N. Murty3 The Bay of Bengal, subjected to monsoonal forcing..., India. Correspondence and requests for materials should be addressed to A.L.G. (email: agordon@ldeo.columbia.edu) Received: 17 October 2016 Accepted: 13 March 2017 Published: 12 April 2017 OPEN www.nature.com/scientificreports/ 2Scientific RepoRts | 7...

  2. Effects of Monetary Shocks on Exchange Rate: Empirical Evidence from India

    Directory of Open Access Journals (Sweden)

    Sharma Chandan

    2017-08-01

    Full Text Available This paper examines the effect of monetary policy shocks on exchange rate in a Multiple Indicator Approach (MIA framework. This study has employed a monetary policy index of key monetary policy instruments in India (Bank rate, Cash Reserve Ratio, Repo and Reverse Repo rates. The study finds the empirical evidence for puzzling behavior of price level and exchange rate. Both price and exchange rate increase initially in response to a contractionary policy shock. Policy shocks affect output, inflation and exchange rate to an appreciable extent over a forecasting horizon of one year.

  3. CIRCULATING ANTIBODIES TO ERYTHROPOIETIN ARE ASSOCIATED WITH LOWER EFFICACY OF RECOMBINANT EPOETIN TREATMENT IN PATIENTS UNDERGOING HAEMODIALYSIS

    Directory of Open Access Journals (Sweden)

    V. D. Nazarov

    2018-01-01

    Full Text Available Biological preparations (BP obtained by gene engineering possess a special characteristic called immunogenicity, i.e. propensity of biological drugs to induce an undesired immune response associated with arising anti-drug antibodies. These antibodies can change BP pharmacokinetics and pharmacodynamics, and therapeutical efficacy. A significant proportion of hemodialysis patients with end-stage renal disease treated by recombinant erythropoietin (rEPO have clinical features of resistance to such therapy. The aim of the study was to investigate whether anti-rEPO antibodies are associated with hemoglobin concentrations (Hb and red blood cells counts (RBC in hemodialysis patients, receiving long-term rEPO therapy. This research was performed at the Research Institute of Nephrology at the First St. Petersburg I.Pavlov State Medical University. Thirty-seven hemodialysis patients (pts with end-stage renal disease and anemia treated with different rEPO formulations were included into the study. The patients were further divided into two groups: those with diminished and normal clinical response to rEPO therapy (DCR, n = 21 vs NCR group, n = 16, respectively. To determine threshold levels of antibodies to rEPO-beta (Roche, Switzerland we tested blood serum samples of 35 healthy blood donors who never received rEPO in the past. Concentration of antibodies was measured by means of dot-blot method. The threshold antibody concentrations were defined by measurement of anti-rEPO concentrations in 2-fold stepwise dilutions (1:10 to 1:200 of blood sera from 35 healthy donors .The threshold value for rEPO-binding antibodies was 20.27 µg/ml (95 CI%±0.43. Antibodies to rEPO were found in 54 % of serum samples in the patients. Anti-rEPO antibodies concentrations correlated with mean values of hemoglobin and erythrocyte counts over a period of 12-months for the entire group of hemodialysis patients (r = -0.368, p = 0.025 and r = -0.336, p = 0.042 respectively

  4. Merged reality for everyone

    OpenAIRE

    Carvalho, Fausto de; Morgado, Leonel

    2017-01-01

    This article addresses some interesting challenges and business opportunities within the promising merged reality ecosystem, which offers the vision of bringing together virtual, augmented and physical realities, seamlessly. The article also links the current status of this field with exploratory research and development work carried out by Altice Labs. Altice Labs info:eu-repo/semantics/publishedVersion

  5. Leverage bubble

    Science.gov (United States)

    Yan, Wanfeng; Woodard, Ryan; Sornette, Didier

    2012-01-01

    Leverage is strongly related to liquidity in a market and lack of liquidity is considered a cause and/or consequence of the recent financial crisis. A repurchase agreement is a financial instrument where a security is sold simultaneously with an agreement to buy it back at a later date. Repurchase agreement (repo) market size is a very important element in calculating the overall leverage in a financial market. Therefore, studying the behavior of repo market size can help to understand a process that can contribute to the birth of a financial crisis. We hypothesize that herding behavior among large investors led to massive over-leveraging through the use of repos, resulting in a bubble (built up over the previous years) and subsequent crash in this market in early 2008. We use the Johansen-Ledoit-Sornette (JLS) model of rational expectation bubbles and behavioral finance to study the dynamics of the repo market that led to the crash. The JLS model qualifies a bubble by the presence of characteristic patterns in the price dynamics, called log-periodic power law (LPPL) behavior. We show that there was significant LPPL behavior in the market before that crash and that the predicted range of times predicted by the model for the end of the bubble is consistent with the observations.

  6. Rural public transportation technologies : user needs and applications : executive summary

    Science.gov (United States)

    1997-02-01

    The Driver/Carrier project was organized in two phases. The goal of this report is to address the three goals stated in the previous section. This report will discuss the overall findings and conclusions of the project research and analysis. The repo...

  7. BiGG Models: A platform for integrating, standardizing and sharing genome-scale models

    DEFF Research Database (Denmark)

    King, Zachary A.; Lu, Justin; Dräger, Andreas

    2016-01-01

    Genome-scale metabolic models are mathematically-structured knowledge bases that can be used to predict metabolic pathway usage and growth phenotypes. Furthermore, they can generate and test hypotheses when integrated with experimental data. To maximize the value of these models, centralized repo...

  8. Return to Work in Out-of-Hospital Cardiac Arrest Survivors

    DEFF Research Database (Denmark)

    Kragholm, Kristian; Wissenberg, Mads; Mortensen, Rikke Normark

    2015-01-01

    BACKGROUND: Data on long-term function of out-of-hospital cardiac arrest survivors are sparse. We examined return to work as a proxy of preserved function without major neurologic deficits in survivors. METHODS AND RESULTS: In Denmark, out-of-hospital cardiac arrests have been systematically repo...

  9. 2018-03-21T13:09:49Z https://www.ajol.info/index.php/all/oai oai:ojs ...

    African Journals Online (AJOL)

    Abdu, SB Hassan, MR Adamu, HY Yashim, SM Oketona, GF Buck, digestibility, Gmelina arborea, maize cobs, red Sokoto bucks An experiment was conducted to ... info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf https://www.ajol.info/index.php/tjas/article/view/94039 Nigerian Journal of ...

  10. Lääne- ja Ida-Virumaal satub löögi alla tuhatkond töökohta / Raivo Raigna

    Index Scriptorium Estoniae

    Raigna, Raivo

    2009-01-01

    Puidu põletamine elektrijaamades on tõstnud ümarpuidu hinda Virumaal kuni 40%, selline kunstlik ja järsk toorme hinnatõus hävitab kahe Virumaa suurtööandja, puitlaastplaatide tootja Repo Vabrikud ja puitmassitehase Estonian Cell konkurentsivõime rahvusvahelistel turgudel ning võib viia sadade töökohtade kaotuseni

  11. Pronomes e passivas do inglês : uma breve perspectivação histórica

    OpenAIRE

    Azuaga, Luísa

    2013-01-01

    O objectivo deste texto é considerar duas características da língua inglesa, pronomes e passivas, que podem eventualmente levantar algumas questões a quem a aprende ou ensina, e analisá-las de uma perspectiva diacrónica, contribuindo, deste modo, para a sua melhor compreensão. info:eu-repo/semantics/publishedVersion

  12. Normal electrocardiographic QT interval in race-fit Standardbred horses at rest and its rate dependence during exercise

    DEFF Research Database (Denmark)

    Pedersen, Philip J; Kanters, Jørgen K.; Buhl, Rikke

    2013-01-01

    Cardiac repolarization, measured as QT and Tpeak to Tend (TpTe) intervals on the ECG, is important, as irregularities caused by diseases, ventricular hypertrophy, drugs and genetic defects can trigger arrhythmias which predispose human patients to syncope and sudden cardiac death. In horses, repo...

  13. El cuerpo extendido : indumentaria mutante en la obra de Ali Schachtschneider

    OpenAIRE

    Nóvoa Vicente, Elena Fernández

    2017-01-01

    The issue of this paper is to explore the concept of the extended body reflecting on clothing and biotechnology activated through Ali Schachtschneider´s work. Going through the different scopes articulated by the Vivorium project, we will look over the taxonomy review that these pieces of work arouse info:eu-repo/semantics/publishedVersion

  14. BENZO[A]PYRENE AND ITS K-REGION DIOL INDUCE DNA DAMAGE IN C3H10T1/2C18 CELLS AS MEASURED BY THE ALKALINE SINGLE CELL GEL (COMET) ASSAY

    Science.gov (United States)

    160. Benzo[a]pyrene and its K-region diol induce DNA damage in C3HlOTl/2Cl8 cells as measured by the alkaline single cell gel (Comet) assay In a continuing series of studies on the genotoxicity ofK-region dihydrodiols of polycyclic aromatic hydrocarbons, we have repo...

  15. Fuel Cell Buses in U.S. Transit Fleets : Current Status 2012

    Science.gov (United States)

    2012-11-12

    This report is the sixth in an annual series of reports that summarize the progress of fuel cell electric bus (FCEB) development in the United States and discuss the achievements and challenges of introducing fuel cell propulsion in transit. The repo...

  16. Reaching researchers: embedding data management support

    OpenAIRE

    Higman, Rosie

    2017-01-01

    Talk given by Rosie Higman to librarians at the CPD25 event on Open Access and Repositories at the Foundling Museum, 26th April 2017 (http://www.cpd25.ac.uk/events/open-access-repositories-event-ref-no-tg3repo/).

  17. A monoclonal antibody based capture ELISA for botulinum neurotoxin serotype B: toxin detection in food

    Science.gov (United States)

    Botulism is a serious foodborne neuroparalyic disease caused by botulinum neurotoxin (BoNT) produced by the anaerobic bacterium Clostridium botulinum. Seven toxin serotypes (A-H) have been described. The majority of human cases of botulism are caused by serotypes A and B followed by E and F. We repo...

  18. Organizing for Networked Information Technologies - Cases in Process Integration and Transformation

    DEFF Research Database (Denmark)

    The book provides seven practical examples of how Danish companies implemented new information technology in order to transform their internal and external business processes. The purpose is to share some of the companies' concerns and hopes during this implementation process, with each case repo...

  19. Sanatooriumist sai tuhande võimaluse spaa hotell / Toivo Tänavsuu

    Index Scriptorium Estoniae

    Tänavsuu, Toivo

    2005-01-01

    Ettevõtluse auhinna Piirkonna Edendaja 2005 pälvinud Pühajärve Puhkekodu AS-i tegevusest ja arenguplaanidest. Lisa: Keskus planeerib juurdeehitust. Piirkonna Edendaja 2005 nominendid. AS Kunda Nordic Tsement, Pühajärve Puhkekodu AS, AS Repo Vabrikud, AS Silbet ja Toom Tekstiil AS

  20. 77 FR 38108 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing of Proposed...

    Science.gov (United States)

    2012-06-26

    ... inter-dealer broker netting members on a blind basis. Standardized, generic CUSIP numbers have been... from the inter-bank funds settlements related to the service, namely, the large interbank funds... value can be effected by simple debits and credits to the accounts of the GCF Repo dealer counterparties...

  1. Püssi plaat saab 30aastaseks / Gerli Romanovitsh

    Index Scriptorium Estoniae

    Romanovitš, Gerli, 1977-

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 22. dets. 2004, lk. 4. Aasta aega Šveitsi investeerimisfirmale Sorbes AG kuulunud Püssi Repo Vabrikud tähistab puitlaastvabrikute kombinaadi 30. sünnipäeva. Praegu toodetakse 170 000 m3 puitlaastplaati aastas

  2. Insecure debt

    NARCIS (Netherlands)

    Matta, R.; Perotti, E.

    2015-01-01

    Does demand for safety create instability ? Secured (repo) funding can be made so safe that it never runs, but shifts risk to unsecured creditors. We show that this triggers more frequent runs by unsecured creditors, even in the absence of fundamental risk. This effect is separate from the

  3. 78 FR 77511 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Approving Proposed Rule...

    Science.gov (United States)

    2013-12-23

    ... the Floating Rate Notes and will continue to do so prior to making Floating Rate Notes eligible for... U.S. Department of the Treasury's Floating Rate Notes Eligible for Netting Service and GCF Repo... the U.S. Department of the Treasury (``Treasury Department'') floating rate notes eligible for the...

  4. Life-Cycle Assessment of Cookstove Fuels in India and China

    Science.gov (United States)

    A life cycle assessment (LCA) was conducted to compare the environmental footprint of current and possible fuels used for cooking within China and India. Current fuel mix profiles are compared to scenarios of projected differences in and/or cleaner cooking fuels. Results are repo...

  5. Personajes y escenarios en las performances de Elena Tejada

    OpenAIRE

    Mendoza, Mihaela Radulescu de Barrio de

    2017-01-01

    The paper focuses on the enunciative aspects of the art performances of the Peruvian artist Elena Tejada to deepen the effects of meaning generated by the theatrical performance. The construction of characters and scenarios provides the necessary contents for the rituals of integration of the public in the symbolic experience that the performances generate info:eu-repo/semantics/publishedVersion

  6. Liquidity and Counterparty Risks Tradeoff in Money Market Networks

    NARCIS (Netherlands)

    Leon Rincon, C.E.; Sarmiento, M.

    2016-01-01

    We examine how liquidity is exchanged in different types of Colombian money market networks (i.e. secured, unsecured, and central bank’s repo networks). Our examination first measures and analyzes the centralization of money market networks. Afterwards, based on a simple network optimization problem

  7. Treatment of anemia of nephrotic syndrome with recombinant erythropoietin

    NARCIS (Netherlands)

    Gansevoort, RT; Vaziri, ND; deJong, PE

    Nephrotic syndrome has been recently shown to cause erythropoietin (EPO) deficiency in humans and experimental models. However, efficacy and safety of recombinant EPO (rEPO) in the treatment of the associated anemia has not been previously investigated. We report a patient with nephrotic syndrome

  8. Physique ou leçons sur les principes généraux de la nature II

    CERN Document Server

    Aristote

    2015-01-01

    Extrait : ""Définition de la nature : elle est dans les êtres, le principe du mouvement et du repos. Des êtres naturels. L'existence de la nature est évidente ; il n'est pas nécessaire de la démontrer.""

  9. Literatura e Lusofonia 2015

    OpenAIRE

    Carlos, Albino; Fonseca, António; Neto, Carmo; Cristóvão, Conceição; Lopes Filho, João; Fanha, José; Luiz Tavares, José; Cardoso "Takas", Luís; Rui, Manuel; Guimarães, Marco; Senna Fernandes, Miguel; Pepetela, -; Cassamo, Suleiman; Tcheka, Tony; Ba Ka Khosa, Ungulani

    2017-01-01

    Literatura e Lusofonia, colectânea dos textos apresentados ao V Encontro de Escritores de Língua Portuguesa. realizado na cidade de Luanda. Câmara Municipal de Luanda e Câmara Municipal de Lisboa info:eu-repo/semantics/publishedVersion

  10. Conservation of genetic diversity in slippery elm (Ulmus rubra) in Wisconsin despite the devastating impact of Dutch elm disease

    Science.gov (United States)

    Forest trees tend to be genetically diverse, a condition related to their longevity, outcrossing mating system and extensive gene flow that maintains high levels of genetic diversity within populations. Forest pest epidemics are responsible for many historic and contemporary population declines repo...

  11. US (United States) Army Aeromedical Research Laboratory Annual Progress Report, FY 1982.

    Science.gov (United States)

    1982-10-01

    lr- mechan i SMS found i n caIda ver tcS t s Progress Fe work wa s compleoted and a repo rt i ssued. Ito data s:! lowoP! cod simil anf toy bet te en...filter contaminants known to exist in the operational environment. Physiological data, heart rate, oxygen tension and respiratory functions as well as

  12. Uue Musta Luige ehitus Kadriorus ähvardab teadmata ajaks seiskuda / Urmas Tooming

    Index Scriptorium Estoniae

    Tooming, Urmas, 1954-

    2009-01-01

    Tallinnas Kadriorus asuv arhitektuurimälestis villa Mon Repos laguneb. 19. sajandist päit puithoone peab taastama firma NG Eesti. Arhitekt Voldemar Herkeli projekteeritud restoran Must Luik on lammutatud. Samale kohale kavandatud Enn Rajasaare projekteeritud hoonet pole veel hakatud ehitama

  13. The design of an asynchronous Tiny RISC TM/TR4101 microprocessor core

    DEFF Research Database (Denmark)

    Christensen, Kåre Tais; Jensen, P.; Korger, P.

    1998-01-01

    This paper presents the design of an asynchronous version of the TR4101 embedded microprocessor core developed by LSI Logic Inc. The asynchronous processor, called ARISC, was designed using the same CAD tools and the same standard cell library that was used to implement the TR4101. The paper repo...

  14. Validation of Left Ventricular Ejection Fraction with the IQ•SPECT System in Small-Heart Patients.

    Science.gov (United States)

    Yoneyama, Hiroto; Shibutani, Takayuki; Konishi, Takahiro; Mizutani, Asuka; Hashimoto, Ryosuke; Onoguchi, Masahisa; Okuda, Koichi; Matsuo, Shinro; Nakajima, Kenichi; Kinuya, Seigo

    2017-09-01

    The IQ•SPECT system, which is equipped with multifocal collimators ( SMART ZOOM) and uses ordered-subset conjugate gradient minimization as the reconstruction algorithm, reduces the acquisition time of myocardial perfusion imaging compared with conventional SPECT systems equipped with low-energy high-resolution collimators. We compared the IQ•SPECT system with a conventional SPECT system for estimating left ventricular ejection fraction (LVEF) in patients with a small heart (end-systolic volume IQ•SPECT. End-systolic volume, end-diastolic volume, and LVEF were calculated using quantitative gated SPECT (QGS) and cardioREPO software. We compared the LVEF from gated myocardial perfusion SPECT to that from echocardiographic measurements. Results: End-diastolic volume, end-systolic volume, and LVEF as obtained from conventional SPECT, IQ•SPECT, and echocardiography showed a good to excellent correlation regardless of whether they were calculated using QGS or using cardioREPO. Although LVEF calculated using QGS significantly differed between conventional SPECT and IQ•SPECT (65.4% ± 13.8% vs. 68.4% ± 15.2%) ( P = 0.0002), LVEF calculated using cardioREPO did not (69.5% ± 10.6% vs. 69.5% ± 11.0%). Likewise, although LVEF calculated using QGS significantly differed between conventional SPECT and IQ•SPECT (75.0 ± 9.6 vs. 79.5 ± 8.3) ( P = 0.0005), LVEF calculated using cardioREPO did not (72.3% ± 9.0% vs. 74.3% ± 8.3%). Conclusion: In small-heart patients, the difference in LVEF between IQ•SPECT and conventional SPECT was less when calculated using cardioREPO than when calculated using QGS. © 2017 by the Society of Nuclear Medicine and Molecular Imaging.

  15. EMOS: Program package for the long-term safety analysis of a repository for radioactive waste, version 4

    International Nuclear Information System (INIS)

    Storck, R.; Buhmann, D.; Hirsekorn, R.P.; Nies, A.; Rausch, H.

    1990-09-01

    Model calculations were performed with the EMOS/REPOS code describing the release of radionuclides from a salt formation, and radionuclide transport in the cap rock was computed separately for one-dimensional or multidimensional dispersion using the SWIFT code. The EMOS code, however, is basically designed so as to allow both the calculation of radionuclide release from a mine opening in a salt formation with the REPOS code, and the subsequent disperson processes in the cap rock and the resulting radiation exposure in the biosphere, with the help of several other modules. These modules have been developed and implemented. Furthermore, the EMOS code was provided with a Monte-Carlo frame, in order to take into account the range of variation of input data, referring to the mine opening, the cap rock, and the biosphere. (orig.) [de

  16. Cell proliferation in the Drosophila adult brain revealed by clonal analysis and bromodeoxyuridine labelling

    Directory of Open Access Journals (Sweden)

    Brand Andrea H

    2009-03-01

    Full Text Available Abstract Background The production of new neurons during adulthood and their subsequent integration into a mature central nervous system have been shown to occur in all vertebrate species examined to date. However, the situation in insects is less clear and, in particular, it has been reported that there is no proliferation in the Drosophila adult brain. Results We report here, using clonal analysis and 5'-bromo-2'-deoxyuridine (BrdU labelling, that cell proliferation does occur in the Drosophila adult brain. The majority of clones cluster on the ventrolateral side of the antennal lobes, as do the BrdU-positive cells. Of the BrdU-labelled cells, 86% express the glial gene reversed polarity (repo, and 14% are repo negative. Conclusion We have observed cell proliferation in the Drosophila adult brain. The dividing cells may be adult stem cells, generating glial and/or non-glial cell types.

  17. CSIR work on improving cybersecurity for the South African industry

    CSIR Research Space (South Africa)

    Taute, Barend JE

    2017-10-01

    Full Text Available Recover Ready to support and collaborate with industry ….. to 11 Early warning detection technology East - west cyberattacks – intranet - anomaly detection – during reconnaissance phase 12 Network Emulation and Simulation Laboratory (NESL... of custom applications • Realistic network traffic generation • Flexibility - client use cases Firewall Host Lightweight Switch OpenVSwitch Router PC Virtual Machine Pentest VM Vulnerable Webserver Eport Ubuntu Repo 14 Cyber Protect - 1 Find...

  18. ORF List: * [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available * orf19.7368; Contig19-2513; complement(50456..51988); PUB1*; polyadenylated RNA-binding protein | not repo...rted to associate with polyribosomes; Eukaryota Candida_albicans Ca19AnnotatedDec2004aaSeq 1fxlA:gb|EAK97614.1| *:gb|EAK97614.1| 37:200 ... 1fxlA

  19. ORF List: * [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available * orf19.7368; Contig19-2513; complement(50456..51988); PUB1*; polyadenylated RNA-binding protein | not repo...rted to associate with polyribosomes; Eukaryota Candida_albicans Ca19AnnotatedDec2004aaSeq 1whxA:emb|CAG84729.1| *:emb|CAG84729.1| 222:319 ... 1whxA

  20. Bacteremia due to Rhodococcus equi in an immunocompetent infant

    OpenAIRE

    P Devi; S Malhotra; A Chadha

    2011-01-01

    Rhodococcus equi , previously known as Corynebacterium equi, is one of the most important causes of zoonotic infection in grazing animals. Increased cases of human infection with R. equi have been reported especially in immunocompromised patients. Infection in immunocompetent patients is extremely rare. We report a case of R. equi bacteremia in a 26-day-old immunocompetent infant with recurrent swellings on different parts of the body. To the best of our knowledge, this is the first ever repo...

  1. Determination and Correction of Persistent Biases in Quantum Annealers

    Science.gov (United States)

    2016-08-25

    for all of the qubits. Narrowing of the bias distribution. To show the correctability of the persistent biases , we ran the experiment described above...this is a promising application for bias correction . Importantly, while the J biases determined here are in general smaller than the h biases , numerical...1Scientific RepoRts | 6:18628 | DOI: 10.1038/srep18628 www.nature.com/scientificreports Determination and correction of persistent biases in quantum

  2. Continuous Integration for Concurrent MOOSE Framework and Application Development on GitHub

    OpenAIRE

    Slaughter, Andrew E.; Peterson, John W.; Gaston, Derek R.; Permann, Cody J.; Andrš, David; Miller, Jason M.

    2015-01-01

    For the past several years, Idaho National Laboratory’s MOOSE framework team has employed modern software engineering techniques (continuous integration, joint application/framework source code repos- itories, automated regression testing, etc.) in developing closed-source multiphysics simulation software (Gaston et al., 'Journal of Open Research Software' vol. 2, article e10, 2014). In March 2014, the MOOSE framework was released under an open source license on GitHub, significantly expandin...

  3. Vecu de la grossesse et maladies infantiles chez les Mahou de la ...

    African Journals Online (AJOL)

    Il ressort que les femmes mahou de la ville de Bouaké associent les connaissances scientifiques et culturelles pour déterminer l'étiologie des maladies infantiles. Le non-respect des consultations prénatales, la mauvaise alimentation de la mère et l'insuffisance de repos favorisent les maladies infantiles. Dans la culture ...

  4. Coexistence of tuberculosis and mammary carcinoma in a goat

    OpenAIRE

    Quintas, Hélder; Alegria, Nuno; Mendonça, Álvaro; Botelho, A.; Alves, A.; Pires, Isabel

    2014-01-01

    Synchronic occurrence of tuberculosis mastitis and mammary cancer is rare in humans and, to the best of our knowledge, not reported in domestic animals. Here, we present a case of a female adult goat of Serrana breed with simultaneous occurrence of a granulomatous mastitis, due to Mycobacterium caprae, and a mammary carcinoma. Both pathological conditions are rare in goats and should be included in differential diagnosis of mammary lesions. info:eu-repo/semantics/publishedVersion

  5. Special Inspector General for Afghanistan Reconstruction

    Science.gov (United States)

    2014-04-30

    election or face violence.367 Three presumptive presidential front- runners (Abdullah, Ghani, and Rassoul) cancelled their appearances in televised...west, aim to build what USAID calls “ resilience ” in areas that are vulnerable to violence and insurgent exploitation.424 CCI implements initiatives...116 more provincial council runners disqualified,” 03/19/2014. EndnotEs 253RepoRt to the united states congRess i April 30, 2014 319 Pajhwok

  6. An Open Challenge Problem Repository for Systems Supporting Binders

    OpenAIRE

    Felty, A.; Momigliano, A.; Pientka, B.

    2015-01-01

    A variety of logical frameworks support the use of higher-order abstract syntax in representing formal systems; however, each system has its own set of benchmarks. Even worse, general proof assistants that provide special libraries for dealing with binders offer a very limited evaluation of such libraries, and the examples given often do not exercise and stress-test key aspects that arise in the presence of binders. In this paper we design an open repository ORBI (Open challenge problem Repo...

  7. Case report

    African Journals Online (AJOL)

    ebutamanya

    11 août 2015 ... 3 des struma ovarii, elle cesse après l'exérèse tumorale. Parfois, un goitre ovarien sécrétant peut mettre au repos l'axe hypothalamo- hypophysaire avec risque d'hypothyroïdie postopératoire. Quelques cas de goitre ovarien avec manifestations d'auto-immunité de type maladie d'Hashimoto ou maladie de ...

  8. Problems of engineering education and their decision involving industry

    OpenAIRE

    R. P. Simonyants

    2014-01-01

    In Russia, the problems of engineering education are connected with political and economic upheavals of the late last century. At the same time, some leading engineering universities in Russia, such as the Bauman Moscow State Technical University (BMSTU) were resistant to the damaging effects of the crisis. But the methodology and experience of their effective work are insufficiently known.The problems of international engineering school development are also known. The first UNESCO World Repo...

  9. Microbiota transplantation and/or CRISPR-Cas in the battle against antimicrobial resistance

    OpenAIRE

    Vila Estapé, Jordi

    2018-01-01

    In the last decades we have witnessed a dramatic increase in infections caused by multidrug-resistant bacteria (MDRB). Organizations such as the European Center for Disease Prevention and Control (ECDC) and the World Health Organization (WHO) consider these infections to be an emerging global disease and a major public health problem. Although the development of new antibacterial drugs seems to have reached a dead end, potential new therapeutic strategies can be pursued [1]. Recently WHO repo...

  10. Index of Submarine Medical Officer’s Qualification Theses 1944-1974

    Science.gov (United States)

    1976-04-01

    USING HYPOTHERMIA AND HYPERBARIC CXYGENATI 1972-3011 0 A CASE REPO+ HYPOBARIC HYPOXIA ABOARD A SUBMERGED SUBMARINE 1972-0014 THE EFFECTS OF ACUTE HYPOXIA...G009 LEVEL. VENTILATORY DYNAMICS UNDER HYPERBARIC STATES.= SUBMARINE MEDICAL QUALIFICATION THESES U. So NAVAL SJBMARINE MEDICAL CENTER SUBMARINE BASE...CONNECTICUT. 23 OCT 62 StJRL ____________ 1962-0019 WOO3D W.- - ____ VENTILATORY DYNAMICS UNDER HYPERBARIC STATES.= SUBMARINE MEDICAL QUALIFICATION THESES

  11. MECP2 duplication phenotype in symptomatic females: report of three further cases

    OpenAIRE

    Novara, Francesca; Simonati, Alessandro; Sicca, Federico; Battini, Roberta; Fiori, Simona; Contaldo, Annarita; Criscuolo, Lucia; Zuffardi, Orsetta; Ciccone, Roberto

    2014-01-01

    Background Xq28 duplications, including MECP2 (methyl CpG-binding protein 2; OMIM 300005), have been identified in approximately 140 male patients presenting with hypotonia, severe developmental delay/intellectual disability, limited or absent speech and ambulation, and recurrent respiratory infections. Female patients with Xq28 duplication have been rarely reported and are usually asymptomatic. Altogether, only fifteen symptomatic females with Xq28 duplications including MECP2 have been repo...

  12. Implementing a Self- Checking PROFIBUS Slave

    OpenAIRE

    Krug, Margrit R.; Lubaszewski, Marcelo S.; Ferreira, Jose M.; Alves, Gustavo R.

    2000-01-01

    This work presents the study and preliminary results of the high level implementation of a self-checking Profibus slave. From an existing VHDL description of the device, a test strategy was studied and implemented, so that the whole circuit has embedded test structures capable to perform at-speed test of the slave. In this paper, we show the used test strategies and implementation results achieved from a synthesis process in a FPGA environment. info:eu-repo/semantics/publishedVersion

  13. Artificial Synaptic Devices Based on Natural Chicken Albumen Coupled Electric-Double-Layer Transistors

    OpenAIRE

    Wu, Guodong; Feng, Ping; Wan, Xiang; Zhu, Liqiang; Shi, Yi; Wan, Qing

    2016-01-01

    Recent progress in using biomaterials to fabricate functional electronics has got growing attention for the new generation of environmentally friendly and biocompatible electronic devices. As a kind of biological material with rich source, proteins are essential natural component of all organisms. At the same time, artificial synaptic devices are of great significance for neuromorphic systems because they can emulate the signal process and memory behaviors of biological synapses. In this repo...

  14. Orthodontic-Surgical Alternatives for Tooth Ankylosis

    OpenAIRE

    Giraldo-Mira, Juan Felipe; Velásquez Velásquez, Mariluz

    2014-01-01

    Treatment for tooth ankylosis poses a big challenge in dentistry. Orthosurgical techniques must be included to obtain a satisfactory esthetic and functional result. The treatment options are surgical removal, segmentary osteotomy with immediate repo- sition and segmentary osteotomy with distraction osteogenesis, which can be done using distractors or orthodontics, thus achieving acceptable long-term outcomes. El tratamiento de dientes anquilosados presenta un gran desafio en odontologia. E...

  15. A potential role for cell-based therapeutics in the treatment of intervertebral disc herniation

    OpenAIRE

    Ganey, Timothy M.; Meisel, Hans

    2002-01-01

    Lower back pain and disc degeneration negatively affect quality of life and impose an enormous financial burden. An extensive body of scientific work has evolved that characterizes the disc, demonstrating spinal anatomy and morphology that contribute to risk and likely promote failure. Ultimately, matrix failure is responsible for mechanical failure, which in turn results in spinal compromise anatomically and subsequent pain. One intervening approach to breaking this sequence has been to repo...

  16. Kinetics of Roasting Decomposition of the Rare Earth Elements by CaO and Coal

    Directory of Open Access Journals (Sweden)

    Shuai Yuan

    2017-06-01

    Full Text Available The roasting method of magnetic tailing mixed with CaO and coal was used to recycle the rare earth elements (REE in magnetic tailing. The phase transformation and decomposition process were researched during the roasting processes. The results showed that the decomposition processes of REE in magnetic tailing were divided into two steps. The first step from 380 to 431 °C mainly entailed the decomposition of bastnaesite (REFCO3. The second step from 605 to 716 °C mainly included the decomposition of monazite (REPO4. The decomposition products were primarily RE2O3, Ce0.75Nd0.25O1.875, CeO2, Ca5F(PO43, and CaF2. Adding CaO could reduce the decomposition temperature of REFCO3 and REPO4. Meanwhile, the decomposition effect of CaO on bastnaesite and monazite was significant. Besides, the effects of the roasting time, roasting temperature, and CaO addition level on the decomposition rate were studied. The optimum technological conditions were a roasting time of 60 min; roasting temperature of 750 °C; and CaO addition level of 20% (w/w. The maximum decomposition rate of REFCO3 and REPO4 was 99.87%. The roasting time and temperature were the major factors influencing the decomposition rate. The kinetics process of the decomposition of REFCO3 and REPO4 accorded with the interfacial reaction kinetics model. The reaction rate controlling steps were divided into two steps. The first step (at low temperature was controlled by a chemical reaction with an activation energy of 52.67 kJ/mol. The second step (at high temperature was controlled by diffusion with an activation energy of 8.5 kJ/mol.

  17. [Neonatological emergencies in delivery room] [Article in Italian] • Il neonatologo ed alcune emergenze in sala parto

    OpenAIRE

    Antonio Boldrini; Rosa Teresa Scaramuzzo

    2014-01-01

    Introduction: In the delivery room the neonatologist may deal with emergencies, not always predictable by pre-natal diagnosis. Among these dangerous situations, we include: i) extremely preterm birth of a newborn very/extremely low birth weight and ii) shoulder dystocia in term newborns. We will discuss in details these two clinical scenarios. Methods: We reviewed the main recent papers about resuscitation of very/extremely low birth weight preterm newborns and about dystocia of shoulder repo...

  18. Case report

    African Journals Online (AJOL)

    abp

    27 avr. 2016 ... Abstract. Nous apportons une observation d'un cas de la maladie de Wilson, révélé par un syndrome parkinsonien. Le diagnostic a reposé sur les troubles neuropsychiques, la présence de l'anneau cornéen de Kayser-Fleischer, et les troubles du métabolisme du cuivre. Le scanner cérébral était normal,.

  19. Svobodný novinář Franta Kocourek

    OpenAIRE

    Jiřička, Jan

    2011-01-01

    This diploma thesis "Freelance journalist Franta Kocourek" deals with the life and career of Franta Kocourek, the important Czechoslovak journalist in the 20. century. Diploma focuses especially on his working in the press media - prestigious periodicals of the First Czechoslovak Republic weekly magazine Přítomnost and daily newspaper Lidové noviny, not too much successful weekly magazine Groš, leaded by himself, and daily newspaper Slovenský hlas. Kocourek especially had concentrated on repo...

  20. Damage Tolerant Repair Techniques for Pressurized Aircraft Fuselages

    Science.gov (United States)

    1994-01-01

    RepoW Techniques for Prwurized Aircraft AXWdOg 4.9 Summary and Conclusions The basics of adhesive bonded repairs for aluminum aircraft fuselages have... of cruise altitude and bending stresses in the plate at the tip of one-sided reinforcements (chapter 5). The expanded Rose model was transformed into a...DEPARTMEN1 OF THE AIR FORCE AGENCY REPORT NUMBER AFIT/CI 2950 P STREET WRIGHT-PATTERSON AFB OH 45433-7765 11. SUPPLEMENTARY NOTES Usa. DISTRUISUIOII

  1. Fire Ants (Solenopsis spp.) and Their Natural Enemies in Southern South America

    OpenAIRE

    Briano, Juan; Calcaterra, Luis; Varone, Laura

    2012-01-01

    We review the fire ant research conducted by the ARS-South American Biological Control Laboratory (SABCL) since 1987 to find a complex of natural enemies in southern South America and evaluate their specificity and suitability for field release as self-sustaining biological control agents. We also include those studies conducted by the ARS-Center for Medical, Agriculture, and Veterinary Entomology in the United States with the SABCL collaboration. Ecological and biological information is repo...

  2. Supplementary Motor Area Activation in Disfluency Perception : An fMRI Study of Listener Neural Responses to Spontaneously Produced Unfilled and Filled Pauses

    OpenAIRE

    Eklund, Robert; Ingvar, Martin

    2016-01-01

    Spontaneously produced Unfilled Pauses (UPs) and Filled Pauses (FPs) were played to subjects in an fMRI experiment. For both stimuli increased activity was observed in the Primary Auditory Cortex (PAC). However, FPs, but not UPs, elicited modulation in the Supplementary Motor Area (SMA), Brodmann Area 6. Our results provide neurocognitive confirmation of the alleged difference between FPs and other kinds of speech disfluency and could also provide a partial explanation for the previously repo...

  3. Prevalence of masturbation and associated factors in a British national probability survey

    OpenAIRE

    Gerressu, Makeda; Mercer, Catherine H.; Graham, Cynthia A.; Wellings, Kaye; Johnson, Anne M.

    2008-01-01

    This is the post-print version of the article. The official published version can be found at the link below. A stratified probability sample survey of the British general population, aged 16 to 44 years, was conducted from 1999 to 2001 (N = 11,161) using face-to-face interviewing and computer-assisted self-interviewing. We used these data to estimate the population prevalence of masturbation, and to identify sociodemographic, sexual behavioral, and attitudinal factors associated with repo...

  4. Electroporation of Mammalian Cells by Nanosecond Electric Field Oscillations and its Inhibition by the Electric Field Reversal

    Science.gov (United States)

    2015-09-08

    Report 3. DATES COVERED (From – To) March 2013 to July 2015 4. TITLE AND SUBTITLE Electroporation of mammalian cells by nanosecond electric field...Prescribed by ANSI Std. Z39.18 1Scientific RepoRts | 5:13818 | DOi: 10.1038/srep13818 www.nature.com/scientificreports Electroporation of mammalian cells...first to demonstrate that mammalian cells can be electroporated by damped sine wave electric stimuli of nanosecond duration. By comparing the

  5. Expanding the Diversity of Mycobacteriophages: Insights into Genome Architecture and Evolution

    OpenAIRE

    Pope, Welkin H.; Jacobs-Sera, Deborah; Russell, Daniel A.; Peebles, Craig L.; Al-Atrache, Zein; Alcoser, Turi A.; Alexander, Lisa M.; Alfano, Matthew B.; Alford, Samantha T.; Amy, Nichols E.; Anderson, Marie D.; Anderson, Alexander G.; Ang, Andrew A. S.; Ares, Manuel; Barber, Amanda J.

    2011-01-01

    Mycobacteriophages are viruses that infect mycobacterial hosts such as Mycobacterium smegmatis and Mycobacterium tuberculosis. All mycobacteriophages characterized to date are dsDNA tailed phages, and have either siphoviral or myoviral morphotypes. However, their genetic diversity is considerable, and although sixty-two genomes have been sequenced and comparatively analyzed, these likely represent only a small portion of the diversity of the mycobacteriophage population at large. Here we repo...

  6. European Consulting Survey 2012 : The Future of European Management Consulting Firms' Business Models

    OpenAIRE

    Kreutzer, Markus; Menz, Markus

    2012-01-01

    This study report provides European management consulting firms' assessment of trends and currently prevailing business models in the industry. It depicts the different threats and opportunities that consulting firms with different business models, consulting foci, sizes, leverage ratios, international orientations, and geographical footprints face; it also reveals these firms' adaptation strategies. Based on an analysis of a survey of 311 consulting firms from 26 European countries, the repo...

  7. Engineering Education: Challenges for Innovation

    OpenAIRE

    Restivo, Teresa; Alves, Gustavo R.

    2014-01-01

    “Engineering Education: Challenges for Innovation” is the scope of the 1st International Conference of the Portuguese Society for Engineering Education (in Portuguese: Sociedade Portuguesa para a Educação em Engenharia, SPEE) [1]. SPEE is a young society now completing four years since its public presentation and launching by the Faculty of Engineering of University of Porto, in February 19, 2010. info:eu-repo/semantics/publishedVersion

  8. Dynamic wind turbine models in power system simulation tool DIgSILENT

    OpenAIRE

    Hansen, A.D.; Jauch, C.; Sørensen, Poul Ejnar; Iov, F.; Blaabjerg, F.

    2004-01-01

    The present report describes the dynamic wind turbine models implemented in the power system simulation tool DIgSILENT (Version 12.0). The developed models are a part of the results of a national research project, whose overall objective is to create amodel database in different simulation tools. This model database should be able to support the analysis of the interaction between the mechanical structure of the wind turbine and the electrical grid during different operational modes. The repo...

  9. Homogentisic acid is the product of MelA, which mediates melanogenesis in the marine bacterium Shewanella colwelliana D.

    OpenAIRE

    Coon, S L; Kotob, S; Jarvis, B B; Wang, S; Fuqua, W C; Weiner, R M

    1994-01-01

    Shewanella colwelliana D is a marine procaryote which produces a diffusible brown pigment that correlates with melA gene expression. Previously, melA had been cloned, sequenced, and expressed in Escherichia coli; however, the reaction product of MelA had not been identified. This report identifies that product as homogentisic acid, provides evidence that the pigment is homogentisic acid-melanin (pyomelanin), and suggests that MelA is p-hydroxyphenylpyruvate hydroxylase. This is the first repo...

  10. RSE et justice sociale : le cas des multinationales pétrolières dans ...

    African Journals Online (AJOL)

    Dans les pays où les institutions apparaissent encore fragiles, les présupposés sur lesquels a reposé la conception moderne de la justice sociale ne sont pas vérifiés. Les questions de justice ne relèvent pas du seul contexte des Etatsnations souverains, et des distributions à opérer entre citoyens égaux en droit, au sein de ...

  11. MARKET RISK ESTIMATION IN (T+-TRANSACTIONS

    Directory of Open Access Journals (Sweden)

    Radik B. Begov

    2016-01-01

    Full Text Available Market risk analysis and estimation are presentedin T+ transactionsas they are used within the Moscow Exchange. There is a need to do so as a result of the cut-off of a new REPO product with Central Counterpartner (CCP. Here repurchase agreement goes through the National Clearing Center (NCC, the last being a bank and a clearing structure within the Moscow Exchange group.NCC actsas an intermediary (so called “Central Counterpartner” between trading participants.REPOs with CCP raisecontractor claims and commitments to the CCP which takes the risk of default on commitments from unfair contract side. The REPO with CCP cut-off made ready a technological platform to implement T+2 trades at the Moscow Exchange. As a result of it there appeared the possibility to enter security purchase/sell contracts partially collateralized. All these transactions (the REPO with CCP, T+ made it a must determining security market risks. The paper is aimed at presenting VaR-like risk estimates. The methods used are from the computer fi nance. Unusual TS rate of return indicator is proposed and applied to find optimal portfolios under the Markowitz approach and their VaRs (losses forecasts given the real “big” share price data and various horizons. Portfolio extreme rate and loss forecasting is our goal. To this end the forecasts are computed for three horizons (2, 5 and 10 days and for three significance levels.There were developed R-, Excel- and Bloomberg-basedsoftware tools as needed. The whole range of proposed computing steps and the tables with charts may be considered as candidates to be included in the future market risk standards.Paper results permit capital market participants to choose the correct (as to the required risk level common stocks.

  12. Regulation of Abortion as State-Socialist Governmentality: The Case of Czechoslovakia

    Czech Academy of Sciences Publication Activity Database

    Dudová, Radka

    2012-01-01

    Roč. 8, č. 1 (2012), s. 123-144 ISSN 1743-923X R&D Projects: GA ČR GAP404/10/0021 Institutional research plan: CEZ:AV0Z70280505 Keywords : abortion * governmentality * bodily citizenship Subject RIV: AO - Sociology, Demography Impact factor: 0.882, year: 2012 http://journals.cambridge.org/repo_A85lXzcV

  13. A Framework for Collateral Risk Control Determination

    OpenAIRE

    Didier Cossin; Zhijiang Huang; Daniel Aunon-Nerin; Fer nando González

    2002-01-01

    This paper derives a general framework for collateral risk control determination in repurchase transactions or repos. The objective is to treat consistently heterogeneous collateral so that the collateral taker has a similar risk exposure whatever the collateral pledged. The framework measures the level of risk with the probability of incurring a loss higher than a pre-specified level given two well-known parameters used to manage the intrinsic risk of collateral: marking to market and haircu...

  14. Myoepithelioma: Benign or malignant â A diagnostic dilemma

    OpenAIRE

    Boon Chye Gan; Andrew Chin; Nor Shahida Abd Mutalib; Hamidah Mamat; Che Yusfarina Che Yusop; Hisham Abdul Rahman

    2017-01-01

    Malignant myoepithelioma of salivary gland which is also known as myoepithelial carcinoma is a rare disease. It has a relatively poor clarification of its biologic behavior, clinicopathologic features and immunohistochemical profile. Presentation may be the same as other benign salivary gland tumors. A high index of suspicion is required to diagnose this rare but malignant condition early and this is especially imperative when there is a recurrent tumor with histopathological examination repo...

  15. Agrosearch

    African Journals Online (AJOL)

    Also, soil moisture release at 50 kPa increased from 7.5 to 14m3m-3 for .... 0.2m depth. With increasing years of planting, bulk density of the ZT decreased,,'(lhile that of CT increased resulting in significant qifferences in the treatments before planting. T x. Y and D x Y ... contradict high(;ir. soil\\IQ.p~stu.r;~ content usually repo.

  16. Global Atmospheric Waves: Mechanical Heating of the Lower Thermosphere.

    Science.gov (United States)

    1982-11-30

    DfVELGP:TVT, LA London, iEiigland. 83 04 20 215 1< 1kLaLA .1_ _ _ REPO)RT DOCUMENTATION PAGE READ 1NSTRUCTIONS; BEFORE COMPLETING FORM 1. Report . uber ...Groves, 1982a). The effect of such uncertainties on F(z ) is however diminished by the predoi ,inan of the ozone eat in;: for exa zle, a1,0. increase in

  17. Framework for successfully implementing an inaugural GRI reporting process

    OpenAIRE

    Dudik, Anna

    2012-01-01

    Project submitted as partial requirement for the conferral of Master in International Management This thesis is a corporate project analyzing the Global Reporting Initiative (GRI) reporting process. Its main objective is to propose a practical framework to guide organizations that plan to engage in first-time voluntary sustainability reporting using GRI’s Sustainability Reporting Guidelines. The thesis provides insight into the exact tasks involved in each stage of the GRI repo...

  18. Pain point system scale (PPSS: a method for postoperative pain estimation in retrospective studies

    Directory of Open Access Journals (Sweden)

    Gkotsi A

    2012-11-01

    Full Text Available Anastasia Gkotsi,1 Dimosthenis Petsas,2 Vasilios Sakalis,3 Asterios Fotas,3 Argyrios Triantafyllidis,3 Ioannis Vouros,3 Evangelos Saridakis,2 Georgios Salpiggidis,3 Athanasios Papathanasiou31Department of Experimental Physiology, Aristotle University of Thessaloniki, Thessaloniki, Greece; 2Department of Anesthesiology, 3Department of Urology, Hippokration General Hospital, Thessaloniki, GreecePurpose: Pain rating scales are widely used for pain assessment. Nevertheless, a new tool is required for pain assessment needs in retrospective studies.Methods: The postoperative pain episodes, during the first postoperative day, of three patient groups were analyzed. Each pain episode was assessed by a visual analog scale, numerical rating scale, verbal rating scale, and a new tool – pain point system scale (PPSS – based on the analgesics administered. The type of analgesic was defined based on the authors’ clinic protocol, patient comorbidities, pain assessment tool scores, and preadministered medications by an artificial neural network system. At each pain episode, each patient was asked to fill the three pain scales. Bartlett’s test and Kaiser–Meyer–Olkin criterion were used to evaluate sample sufficiency. The proper scoring system was defined by varimax rotation. Spearman’s and Pearson’s coefficients assessed PPSS correlation to the known pain scales.Results: A total of 262 pain episodes were evaluated in 124 patients. The PPSS scored one point for each dose of paracetamol, three points for each nonsteroidal antiinflammatory drug or codeine, and seven points for each dose of opioids. The correlation between the visual analog scale and PPSS was found to be strong and linear (rho: 0.715; P <0.001 and Pearson: 0.631; P < 0.001.Conclusion: PPSS correlated well with the known pain scale and could be used safely in the evaluation of postoperative pain in retrospective studies.Keywords: pain scale, retrospective studies, pain point system

  19. Perspectives on Monetary Policy and Cost of Capital: Evidence from Turkey

    Directory of Open Access Journals (Sweden)

    Turguttopbas Neslihan

    2017-05-01

    Full Text Available The target of monetary policy is generally set as to create an environment of manageable employment and affordable long-term interest rates. However, priorities of central banks may differ depending on economic and financial circumstances of individual countries. Modern approaches to monetary policy transmission can be grouped under two headings, Money View and Credit View. The money view concentrates on interest rates to explain the effects of monetary policy on aggregate spending by creating an interest rate channel. The credit channel transmission approach focuses on the supply of credits by banks following a monetary policy shift in interest rates. In 2010, the Central Bank of Turkey (CBT developed an interest rate corridor shaped by one-week and overnight repo lending to the financial banks to absorb excessive volatility caused by short-term capital inflows. Under this framework, the CBT implements its monetary policy in two ways; firstly it can alter the interest rates of weekly repo as well as O/N lending rate. Secondly, it can configure the funding structure it provides to the financial intermediaries. In such a framework, the interest rate transmission mechanism has been operated by two benchmark interest rates, one of which is the weighted average of the cost of funds provided by the CBT and the other is the interest rate in Borsa Istanbul (BIST money market transactions at an overnight maturity. There is a strong co-movement between the interest rates and they are affected by the movements in the CBT lending rate in both directions. Interest rates applied to deposits and loans by banks are affected by the policy rate (CBT Average Funding Rate and the market rate (BIST O/N Repo Rate.

  20. Transfigured paintings

    OpenAIRE

    Bronze, Manuela, 1955-

    2017-01-01

    This paper aims to reflect heuristically upon two sets of works by the painter Henrique Silva – “Interactive Objects” and “Video Art” – in order to assay on what, at first sight looks dissimilar, but has the same kind of relationship between the author and the material, raising in the viewer a possibility of game that, from a gaze, tries to identify in the different planes a figuration that in the development of the visual process is transfigured info:eu-repo/semantics/publishedVersion...

  1. Incontinencia fecal del adulto

    OpenAIRE

    Vergara A,M. Teresa; Suárez M,Juan; Orellana G,Hernán; Cofré L,Pamela; Germain P,Fernando; Stanley E,William; Sivori H,Javiera; Cruz M,Cecilia

    2011-01-01

    El propósito de esta revisión es actualizar los conocimientos sobre esta patología, destacando su evolución clínica, estudio y tratamiento, aspectos que ameritan un enfoque multidisciplinario, ya que, además de su compleja fisiopatología, puede asociarse a incontinencia urinaria y prolapso de los tres compartimentos de la pelvis. La incontinencia fecal (IF) constituye una patología altamente prevalente que afecta al menos un 2% de la población y hasta el 45% de los pacientes en casas de repos...

  2. Downstream Stockton Assessments

    Science.gov (United States)

    1992-01-01

    Collins et al. (1983), Heldman (1960), Holland (1985), Kaplan et al. (1967), McMillan (1965 and 1968), Moffat and Houston (1986), Nichols et al. (1980...along the Sac River by Calabrese et al. (1968 and 1969) and Kaplan et al. (1967). Investigations by Perttula and Purrington (1983:118) focused on Woodland...23CE446. WA Repos Daownmeam Ssoclon Assessment pe97 TEST UNIT 2 WEST WALL PROFILE . .. . ... 4.MW q04 z. .- ) -~’Ail MA2 " -4,P A ’V 1OYR3/2 silt

  3. GIANT GLUTEAL LIPOMA: A CASE REPORT AND REVIEW OF LITERATURE

    OpenAIRE

    PRASHANT HOMBAL

    2015-01-01

    Introduction : Lipoma is one of the most common benign mesenchymal tumor which can occur in almost in all organs of the body where fat normally exists, so called as universal tumor or ubiquitous tumor. Lipomas are slow growing that rarely reach a size more than 2-3cms. Lesions larger than 5cms, so called giant lipomas are seldom found inside the muscle compressing nervous-vascular structures. The large and deep seated lipomas represent a real diagnostic and therapeutic challenge. Case repo...

  4. Graphite Oxide: An Interesting Candidate for Aqueous Supercapacitors

    OpenAIRE

    Lobato Ortega, Belén; Wendelbo, Rune; Barranco, Violeta; Álvarez Centeno, Teresa

    2014-01-01

    A graphite oxide, obtained on a large scale at low cost as an intermediate in the graphene production, achieves specific capacitances (159 Fg−1 in H2SO4 and 82 Fg−1 in (C2H5)4NBF4 in acetonitrile) that compete with those of activated carbons and largely surpass the values obtained with graphene nanoplatelets. More promising, the high electrode density leads to volumetric capacitances of 177 and 59 F cm−3 in the aqueous and the organic electrolytes, respectively, which are above most data repo...

  5. Optical communication beyond orbital angular momentum

    CSIR Research Space (South Africa)

    Trichili, A

    2016-06-01

    Full Text Available :27674 | DOI: 10.1038/srep27674 www.nature.com/scientificreports Optical communication beyond orbital angular momentum Abderrahmen Trichili1, Carmelo Rosales-Guzmán2, Angela Dudley2,3, Bienvenu Ndagano2, Amine Ben Salem1, Mourad Zghal1,4 & Andrew Forbes2 Mode....rosalesguzman@wits.ac.za) received: 29 March 2016 Accepted: 24 May 2016 Published: 10 June 2016 OPEN www.nature.com/scientificreports/ 2Scientific RepoRts | 6:27674 | DOI: 10.1038/srep27674 Results Consider a LG mode in cylindrical coordinates, at its waist plane (z = 0), described...

  6. The abrupt onset of the modern South Asian monsoon winds

    Digital Repository Service at National Institute of Oceanography (India)

    Betzler, C.; Eberli, G.P.; Kroon, D.; Wright, J.D.; Swart, P.K.; Nath, B.N.; Alvarez-Zarikian, C.A.; Alonso-Garcia, M.; Bialik, O.M.; Blattler, C.L.; Guo, J.; Haffen, S.; Horozal, S.; Inoue, M.; Jovane, L.; Lanci, L.; Laya, J.C.; Mee, A.L.H.; Ludmann, T.; Nakakuni, M.; Niino, K.; Petruny, L.M.; Pratiwi, S.D.; Reijmer, J.J.G.; Reolid, J.; Slagle, A.L.; Sloss, C.R.; Su, X.; Yao, Z.; Young, J.R.

    :29838 | DOI: 10.1038/srep29838 www.nature.com/scientificreports The abrupt onset of the modern South Asian Monsoon winds Christian Betzler1, Gregor P. Eberli2, Dick Kroon3, James D. Wright4, Peter K. Swart2, Bejugam Nagender Nath5, Carlos A. Alvarez....betzler@uni-hamburg.de) Received: 25 April 2016 accepted: 21 June 2016 Published: 20 July 2016 OPEN www.nature.com/scientificreports/ 2Scientific RepoRts | 6:29838 | DOI: 10.1038/srep29838 control, and we propose that the post Miocene Climate Optimum cooling, together...

  7. Determination of Selected Properties of Teletype Parts.

    Science.gov (United States)

    1985-10-01

    THtS REPORT IS NOT TO BC USED IN WHOLE OR IN PART rOR ADVERTISING OR SALES PROMOTION PURPOSES ASD $1 64 PNCVIOus COTION OF THIS FORM MAY at useo...REPoRT 1s NOT TO BE USED IN WHOLE of IN PART FOa AOvCRTsINO oR SALES PROMoTIoN PuRPW-- PR S* P0gwSOUS -oD ION Of .. . , FOM MAY O uSTm. AI-W---,AT AS ?M 57

  8. Non-abelian Z-theory: Berends-Giele recursion for the α{sup ′}-expansion of disk integrals

    Energy Technology Data Exchange (ETDEWEB)

    Mafra, Carlos R. [STAG Research Centre and Mathematical Sciences, University of Southampton,Southampton (United Kingdom); Institute for Advanced Study, School of Natural Sciences,Einstein Drive, Princeton, NJ 08540 (United States); Schlotterer, Oliver [Max-Planck-Institut für Gravitationsphysik, Albert-Einstein-Institut,Am Mühlenberg 1, 14476 Potsdam (Germany)

    2017-01-09

    We present a recursive method to calculate the α{sup ′}-expansion of disk integrals arising in tree-level scattering of open strings which resembles the approach of Berends and Giele to gluon amplitudes. Following an earlier interpretation of disk integrals as doubly partial amplitudes of an effective theory of scalars dubbed as Z-theory, we pinpoint the equation of motion of Z-theory from the Berends-Giele recursion for its tree amplitudes. A computer implementation of this method including explicit results for the recursion up to order α{sup ′7} is made available on the website repo.or.cz/BGap.git.

  9. Design of rotating electrical machines

    CERN Document Server

    Pyrhonen , Juha; Hrabovcova , Valeria

    2013-01-01

    In one complete volume, this essential reference presents an in-depth overview of the theoretical principles and techniques of electrical machine design. This timely new edition offers up-to-date theory and guidelines for the design of electrical machines, taking into account recent advances in permanent magnet machines as well as synchronous reluctance machines. New coverage includes: Brand new material on the ecological impact of the motors, covering the eco-design principles of rotating electrical machinesAn expanded section on the design of permanent magnet synchronous machines, now repo

  10. Syndrome parkinsonien secondaire à une maladie de Wilson chez ...

    African Journals Online (AJOL)

    Nous apportons une observation d'un cas de la maladie de Wilson, révélé par un syndrome parkinsonien. Le diagnostic a reposé sur les troubles neuropsychiques, la présence de l'anneau cornéen de Kayser-Fleischer, et les troubles du métabolisme du cuivre. Le scanner cérébral était normal, et l'IRM cérébrale a montré ...

  11. Productivity tips for developers

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    I like to read about productivity tools and techniques, but the problem is - most of them are completely overrated, the tips are not that useful or they are too difficult to implement. But, sometimes I can find some stuff that really makes me think "damn, how could I live without this before?!". Today, I would like to share some of them and hopefully hear about the tips and tricks that you use. Maybe we can find a way to share them somehow (github repo/forum)?

  12. Combating gender stereotypes in the education system: success stories

    OpenAIRE

    Alvarez, Teresa

    2015-01-01

    GEC 2015. Conferência realizada em Helsínquia, de 9-10 october 2014. Conferência de Abertura do Painel 2 – Combating gender stereotypes in the education system: success stories, da Conferência promovida pelo Conselho da Europa sobre “Combating gender stereotypes in and through education”. Apresentam-se alguns desafios decorrentes do combate ao sexismo na escola e propõem-se algumas linhas de ação, ao nível individual, coletivo, organizacional e institucional. info:eu-repo/semantics/pub...

  13. As comunicações interpessoais e as redes informáticas

    OpenAIRE

    Nunes, Jerónimo

    2015-01-01

    [...] «Com a implantação das primeiras redes informáticas, no início da década de oitenta do século passado, começaram a surgir os primeiros programas informáticos de suporte às comunicações interpessoais assíncronas com a participação de múltiplos emissores ou recetores, tirando partidos das capacidades do computador para armazenamento e processamento das informações (mensagens) transmitidas pelos intervenientes.» [...] info:eu-repo/semantics/publishedVersion

  14. Comparaison de deux modes de préparation des médicaments dans une MRS en Communauté germanophone : impact quantitatif et qualitatif sur la pharmacothérapie

    OpenAIRE

    Van Hees, Thierry; Schroeder, Béatrice

    2010-01-01

    1) Introduction La préparation de semainiers pour les patients des maisons de repos et de soins (MRS) par le pharmacien d’officine permet de diminuer les erreurs liées à l’administration des médicaments. Outre ce bénéfice, l’accès pour le pharmacien à l’ensemble du traitement devrait faciliter la validation pharmaceutique des prescriptions et le développement de soins pharmaceutiques de qualité pour les patients résidant en communauté. 2) Contexte de l’étude La MRS étudiée e...

  15. Medical Entomology Studies - IX. The Subgenus Christophersiomyia of the Genus Aedes (Diptera: Culicidae) (Contributions of the American Entomological Institute. Volume 14, Number 2)

    Science.gov (United States)

    1977-01-01

    22-VI-1975, Peyton and Huang), 3d, 3$ terminalia. THAILAND. Chiang Mai . Chiang Mai (25-V-1952, D. C. and E. B. Thurman), Id, ld terminalia; Doi...the labels with pinned adults from Cambodia read “repos sous bois” and “cascade, for& ” Adults also have been taken at light traps in Chiang Mai , Thailand...Lahore District (1962, D. J. Gould), 17?. THAILAND. Chiang Mai . Hoad, Huay Mae Lon (8-X-1963, Neely, Oonruan and Sahem), 6d, 6d terminalia, 5?, 3

  16. Agreement for depression diagnosis between DSM-IV-TR criteria, three validated scales, oncologist assessment, and psychiatric clinical interview in elderly patients with advanced ovarian cancer

    OpenAIRE

    Rhondali, Wadih; Freyer, Gilles; Adam, Virginie; Filbet, Maril?ne; Derzelle, Martine; Abgrall-Barbry, Gaelle; Bourcelot, Sophie; Machavoine, Jean-Louis; Chomat-Neyraud, Muriel; Gisserot, Olivier; Largillier, R?mi; Le Rol, Annick; Priou, Frank; Saltel, Pierre; Falandry, Claire

    2015-01-01

    Wadih Rhondali,1 Gilles Freyer,2 Virginie Adam,3 Marilène Filbet,4 Martine Derzelle,5 Gaelle Abgrall-Barbry,6 Sophie Bourcelot,7 Jean-Louis Machavoine,8 Muriel Chomat-Neyraud,9 Olivier Gisserot,10 Rémi Largillier,11 Annick Le Rol,12 Frank Priou,13 Pierre Saltel,14 Claire Falandry15 1Clinique Mon Repos, Clinea, Marseille, France; 2Medical Oncology Unit, Centre Hospitalier Lyon Sud, Université Lyon 1, Pierre-Benite, France; 3Institut de Cancérologie ...

  17. Calculation of radiological consequences of a radioactive matter release into the biosphere from a final repository using the code BioTREND; Berechnung radiologischer Konsequenzen der Freisetzung radioaktiver Stoffe aus einem Endlager in die Biosphaere mit dem Programm BioTREND

    Energy Technology Data Exchange (ETDEWEB)

    Reiche, Tatiana; Becker, Dirk-Alexander

    2014-09-15

    The aim of the work was the development of a module for the code RepoTREND that allows the evaluation of radiation exposure in the biosphere. The selection of the characteristics relevant for the risk assessment is described. The program module bioTREND is based on the results of fission product release and dispersion calculations and a separate biosphere modeling. Exposure data (annual effective doses and organ doses) can be calculated for individuals and collectives. Optional is the calculation of radiotoxicity concentrations and radiotoxicity fluxes. Several recommendations for the improvement of the calculation module are included.

  18. Streamlining library services what we do, how much time it takes, what it costs, and how we can do it better

    CERN Document Server

    Dougherty, Richard M

    2008-01-01

    Librarianship is a service profession and not a bottom-line oriented business. As such, librarians don't normally assign a high priority to efficiency of operations; however, opportunities to improve daily jobs and enhance services are being overlooked every day. Advances in technology drive change at a rapid pace and keeping up is both expensive and time consuming. Tight budgets have made keeping up with technology especially difficult. And while some activities in libraries, such as in-person ready reference and circulation of books and journals have declined, many libraries continue to repo

  19. Wholesale funding, coordination, and credit risk

    OpenAIRE

    Zhang, Lei; Zhang , Lin; Zheng, Yong

    2013-01-01

    We use the global games approach to study key factors affecting the credit risk\\ud associated with roll-over of bank debt. When creditors are heterogenous, these include\\ud the extent of short-term borrowing and capital market liquidity for repo financing.\\ud Specifically, in a model with a large institutional creditor and a continuum of small\\ud creditors independently making their roll-over decisions based on private information,\\ud we find that increasing the proportion of short-term debt and/...

  20. Diagnostic des systèmes de culture à base de mil [ Pennisetum ...

    African Journals Online (AJOL)

    Objectif : Le présent travail a pour objectif, de faire un état des lieux des systèmes de production à base de mil en Côte d'Ivoire septentrionale afin de proposer de nouvelles pistes d'amélioration. Méthodologie et résultats : L'approche méthodologique s'est reposée sur une enquête auprès des paysans sur le terrain dans ...

  1. El Mercado Europeo de Productos Orgánicos de Comercio Justo

    OpenAIRE

    Garibay, Salvador; Richter, Toralf

    2005-01-01

    Los países centroamericanos son importantes productores de productos orgánicos. Su base de exportaciones, sin embargo, es altamente dependiente de un número limitado de productos (café, cacao, banano, azúcar) lo que atenta contra la sostenibilidad del sector exportador. Por lo tanto, hay una urgente necesidad de diversificar la base de exportaciones y de desarrollar mercados nacionales y regionales, los cuales están creciendo continuamente y tienen un gran potencial. El propósito de este repo...

  2. Is pain assessment feasible as a performance indicator for Dutch nursing homes? A cross-sectional approach.

    Science.gov (United States)

    Boerlage, Anneke A; Masman, Anniek D; Hagoort, Jacobus; Tibboel, Dick; Baar, Frans P M; van Dijk, Monique

    2013-03-01

    Quality of care gains transparency with the help of performance indicators. For Dutch nursing homes, the current set of performance indicators does not include pain. To determine the feasibility of pain assessment as performance indicator, information about pain prevalence and analgesic prescription in one nursing home was collected. Within the time span of 3 days, pain intensity was measured in 91% of the residents (201 out of 221), either with a numeric rating scale, a verbal rating scale, or the Rotterdam Elderly Pain Observation Scale (REPOS). Numerical rating was used for 72%, verbal rating for 3%, and REPOS observation for 25% of the residents. Pain was substantial in 65 residents (32%), who received the following analgesic prescription: World Health Organization (WHO) step 1, 45%; WHO step 3, 12%; and neuroactive agents, 5%. Thirty-eight percent of these residents were in pain and received no analgesics. Residents with substantial pain significantly more often received analgesics (p = .007). Results suggest that pain assessment is feasible in a nursing home and would stimulate staff attention to pain. Further investigation is necessary to find out if a pain algorithm is feasible and will lead to improved pain treatment. Copyright © 2013 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved.

  3. SECURITIZATION AS A TOOL OF BANK LIQUIDITY AND FUNDING MANAGEMENT BEFORE AND AFTER THE CRISIS: THE CASE OF THE EU

    Directory of Open Access Journals (Sweden)

    Olga Teplova

    2013-02-01

    Full Text Available Before the financial crisis securitization was commonly considered an efficient way of replacing illiquid assets with liquid securities (ABS, in which the risk was supposed to be adequately compensated by the tranching techniques. However, with the emergence of the crisis investors became more risk aversive and reluctant to incur ABS due to the rapidly deteriorating quality of the underlying assets caused by poor macroeconomic fundamentals. The limited adverse effects of the poor collateral performance is the main reason why chances for recovery of the ABS market in the EU are estimated more highly than in the USA. The analysis indicates that, driven by the ECB repo operations, the securitization market has almost lost the pre-crisis motives behind the issuance of ABS. Banks’ attitudes toward securitization as a refinancing tool and a mechanism to extract additional profit underwent a shift. As the findings of the article suggest, after the crisis securitization is widely seen by banks as a liquidity tool within the frame of repo deals with the ECB, and to a lesser extent as a refinancing tool. Market regulation contributed considerably to this shift.

  4. Aversion to ambiguity and willingness to take risks affect therapeutic decisions in managing atrial fibrillation for stroke prevention: results of a pilot study in family physicians

    Directory of Open Access Journals (Sweden)

    Raptis S

    2017-09-01

    Full Text Available Stavroula Raptis,1,* Jia Ning Chen,2,* Florencia Saposnik,2 Roman Pelyavskyy,2 Andrew Liuni,3 Gustavo Saposnik2,4 On behalf of the Stroke Outcomes Research Canada Working Group (SORCan- www.sorcan.ca 1Applied Health Research Centre, Li Ka Shing Knowledge Institute, 2Stroke Outcomes and Decision Neuroscience Research Unit, Department of Medicine, St. Michael’s Hospital, University of Toronto, Toronto, 3Medical Department, Boehringer Ingelheim (Canada Ltd., Burlington, ON, Canada; 4Neuroeconomics and Decision Neuroscience, Department of Economics, University of Zurich, Zurich, Switzerland *These authors contributed equally to this work Background: Anticoagulation is the therapeutic paradigm for stroke prevention in patients with atrial fibrillation (AF. It is unknown how physicians make treatment decisions in primary stroke prevention for patients with AF. Objectives: To evaluate the association between family physicians’ risk preferences (aversion risk and ambiguity and therapeutic recommendations (anticoagulation in the management of AF for primary stroke prevention by applying concepts from behavioral economics. Methods: Overall, 73 family physicians participated and completed the study. Our study comprised seven simulated case vignettes, three behavioral experiments, and two validated surveys. Behavioral experiments and surveys incorporated an economic framework to determine risk preferences and biases (e.g., ambiguity aversion, willingness to take risks. The primary outcome was making the correct decision of anticoagulation therapy. Secondary outcomes included medical errors in the management of AF for stroke prevention. Results: Overall, 23.3% (17/73 of the family physicians elected not to escalate the therapy from antiplatelets to anticoagulation when recommended by best practice guidelines. A total of 67.1% of physicians selected the correct therapeutic options in two or more of the three simulated case vignettes. Multivariate

  5. Effect of short-term intravenous ascorbic acid on reducing ferritin in hemodialysis patients.

    Science.gov (United States)

    Jalalzadeh, M; Shekari, E; Mirzamohammadi, F; Ghadiani, M H

    2012-05-01

    Resistance to recombinant erythropoietin (rEPO) in hemodialysis patients may be due to inadequate iron recruitment and defect in iron use. In this cross over randomized clinical trial, 30 hemodialysis patients with serum ferritin levels of ≥500 ng/ml, hemoglobin ≤11.0 g/dl, and transferrin saturation (TSAT) of 20% or less were administrated intravenous iron (50-100 mg/wk) and rEPO (120-360 U/kg/wk) for 6 months. Patients were excluded if there was a clear explanation for rEPO hyporesponsiveness. Patients were divided into two groups. Group1 received standard care and 500 mg of intravenous ascorbic acid (IVAA) with each dialysis session in the first week of each month for a total of 3 months. Group 2 received standard care only. After 2 month washout period, groups were crossed over. Each month hemoglobin (Hb) was assessed. Iron, TIBC (transferrin iron binding capacity), TSAT, iPTH (intact parathyroid hormone), liver enzymes, albumin and cholesterol levels were measured every 3 months. After 3 months of intervention, Hb significantly increased from 10.11 to 12.19 g/dl (P <0 0.001; 95% confidence interval [CI] 2.7-1.4) and TSAT increased from 18.9 to 28.1% (P = 0.008; 95% CI 0.09-3), while ferritin and serum iron declined significantly from 1391 to 938 ng/ml (P = 0.001; 95% CI 216-689), 97.2 to 64.6 (P = 0.001; 95% CI 14.8-50.4) in the study group. Change of Hb over time in IVAA group was significant (P < 0.0005). There were significant differences between two groups in change of Hb level over time (P < 0.0005) and treatment effect (P = 0.002). Baseline laboratory tests were similar in the two groups and there was no carry over effect at phase 2. We showed that low amount of IVAA could reduce ferritin level and enhance Hb and TSAT, suggesting improved iron utilization.

  6. Clinical Profile and Response to Chemotherapeutic Agents in Non-specific Urethritis

    Directory of Open Access Journals (Sweden)

    R K Pandhi

    1984-01-01

    Full Text Available The epidemiological and clinical profile of 159 patients having non-specific iiretbritis is repoed. The majority (67.39o of patients were unm and most (70.4% of the we m re in the age group of 21-30 years. The incubation period in the majority (69.2% of patients was 1-4 weeks. Almost all the (98.1% patients complained of dysuria but urethral discharge was seen only in 48.4% of patients. Out of tetracycline′s doxycline, erythromycin and cotrimoxazole tried in this study, tetracycline′s in the dosage of 2 gm/day for 3 weeks was found to give the best (90.5%′cure rate.

  7. Situaciones didácticas en el contexto de ingeniería civil: caso infiltración de agua en un suelo específico

    OpenAIRE

    Hernández, Hipólito; Rodríguez, Ruth; de la Cruz, Adriana

    2010-01-01

    En la presente investigación se abordó el problema de infiltración de agua en un suelo específico, en consecuencia se exploró una situación didáctica, considerando la noción de predicción como práctica social en la modelación matemática de este fenómeno físico. Se parte de la epistemología inicial del binomio de Newton y la serie de Taylor, como marco de referencia para el estudio del diseño de la situación, donde la práctica de predicción es incorporada de forma intencional. A la vez se repo...

  8. Tools for Reproducibility and Extensibility in Scientific Research

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    Open inquiry through reproducing results is fundamental to the scientific process. Contemporary research relies on software engineering pipelines to collect, process, and analyze data. The open source projects within Project Jupyter facilitate these objectives by bringing software engineering within the context of scientific communication. We will highlight specific projects that are computational building blocks for scientific communication, starting with the Jupyter Notebook. We will also explore applications of projects that build off of the Notebook such as Binder, JupyterHub, and repo2docker. We will discuss how these projects can individually and jointly improve reproducibility in scientific communication. Finally, we will demonstrate applications of Jupyter software that allow researchers to build upon the code of other scientists, both to extend their work and the work of others.    There will be a follow-up demo session in the afternoon, hosted by iML. Details can be foun...

  9. Solubilities of some hydrous REE phosphates with implications for diagenesis and sea water concentrations

    International Nuclear Information System (INIS)

    Jonasson, R.G.; Bancroft, G.M.; Nesbitt, H.W.

    1985-01-01

    Solubility product determinations suggest that the hydrous phosphates of the rare earths, REPO 4 .xH 2 O, are important in controlling the sea water REE concentrations. Two of these solids, rhabdophane, (P6 2 22) and 'hydrous xenotime', (I4 1 /amd), have been synthesized at 100 C via the acid hydrolysis of the respective REE pyrophosphate. The solubility products at infinite dilution were determined to be pK 0 = 24.5, (La at 25 C); 26.0, (Pr at 100 C); 25.7, (Nd at 100 C); and 25.5, (Er at 100 C). On the basis of calculations involving the reaction of Re 3+ with apatite to form the hydrous phosphate, the lanthanum concentration in sea water is predicted to be about 140 pmol/L. Laboratory experiments support the hypothesis that apatite is a substrate for reactions with dissolved REE. (author)

  10. A peptide-binding assay for the disease-associated HLA-DQ8 molecule

    DEFF Research Database (Denmark)

    Straumfors, A; Johansen, B H; Vartdal, F

    1998-01-01

    The study of peptide binding to HLA class II molecules has mostly concentrated on DR molecules. Since many autoimmune diseases show a primary association to particular DQ molecules rather than DR molecules, it is also important to study the peptide-binding properties of DQ molecules. Here we repo......-affinity binders, whereas peptides derived from myelin basic protein were among the low-affinity binders. The sequence of the high-affinity peptides conformed with a previously published peptide-binding motif of DQ8.......The study of peptide binding to HLA class II molecules has mostly concentrated on DR molecules. Since many autoimmune diseases show a primary association to particular DQ molecules rather than DR molecules, it is also important to study the peptide-binding properties of DQ molecules. Here we report...

  11. X-ray Absorption Spectroscopy of the Rare Earth orthophosphates

    International Nuclear Information System (INIS)

    Shuh, D.K.; Terminello, L.J.; Boatner, L.A.; Abraham, M.M.

    1993-06-01

    X-ray Absorption Spectroscopy (XAS) of the Rare Earth (RE) 3d levels yields sharp peaks near the edges as a result of strong, quasi-atomic 3d 10 4f n → 3d- 9 4f n+1 transitions and these transitions exhibit a wealth of spectroscopic features. The XAS measurements of single crystal REPO 4 (RE = La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Er) at the 3d edge were performed in the total yield mode at beam line 8-2 at the Stanford Synchrotron Radiation Laboratory (SSRL). The XAS spectra of the RE ions in the orthophosphate matrix generally resemble the XAS of the corresponding RE metal. This is not unexpected and emphasizes the major contribution of the trivalent state to the electronic transitions at the RE 3d edges. These spectra unequivocally identify the transitions originating from well-characterized RE cores and correlate well with previous theoretical investigations

  12. La mémoire et l’écrit : l’abbaye de Cluny et ses archives (Xe-XVIIIe siècle

    Directory of Open Access Journals (Sweden)

    Sébastien Barret

    2009-10-01

    Full Text Available L'abbaye, le réseau monastique puis l’ordre de Cluny sont un monument tant de l’histoire du Moyen Âge européen que de son historiographie. Son édification a reposé entre autres sur une base documentaire, dont les restes encore impressionnants témoignent de ce qui fut vraisemblablement l’un des plus beaux fonds d’archives des périodes médiévale et moderne. Comme l’on dispose de témoignages certes épars, mais répartis sur une vaste fourchette chronologique, il était naturel de chercher à interr...

  13. «A transfiguração espiritual do amor cortês em Bernardo de Claraval»

    OpenAIRE

    Rosa, José Maria Silva

    2005-01-01

    Permitam-me começar com uma pergunta: Será que havia amor na Idade Média? Será que se amava nesses «tempos sombrios»? Afinal, a Idade Média não é tão-só aquele Mar de Trevas, com o cortejo dos seus apocalípticos horrores, as invasões bárbaras, o obscurantismo, a bestialidade das procissões dos autoflagelantes, a brutalidade, a pobreza extrema e esgazeada, a caça às bruxas, as Cruzadas, a Inquisição? Enfim, em três palavras: Peste, Fome e Guerra? info:eu-repo/semantics/publishedVersion...

  14. The impact of monetary policy on the economic growth of a small and open economy: The case of South Africa

    Directory of Open Access Journals (Sweden)

    V Khabo

    2014-08-01

    Full Text Available This study evaluates the impact of monetary policy on the economic growth of a small and open economy like that of South Africa. Structuralists contend that changes in money supply (M3 and inflation (CPI are not significantly related to changes in economic growth (GDP, while orthodox economists argue that they are. Stucturalists also hold that monetary authorities cannot control M3, whereas orthodox economists believe they can. To structuralists, when monetary authorities pursue an expansionary policy, the opposite effect is achieved. Orthodox economists counter this argument. The ADT test statistic against the McKinnon critical values was used and it was found (i that money supply changes and inflation are significantly related to changes in economic growth, and (ii whereas monetary authorities can control M3 through the repo rate,  they cannot keep it within set targets.

  15. Aliénation et idéologie

    OpenAIRE

    Kanabus, Benoît; Popa, Délia

    2017-01-01

    Dès lors, on entend mieux la question sur laquelle se referment les mille pages du Marx : « La pensée de Marx nous place devant la question abyssale : qu’est-ce que la vie » ? Cette question peut être reposée à nouveaux frais à l’âge du capitalisme avancé, où, comme le notait Adorno, la vie est devenue « l’idéologie de sa propre absence ». La recherche d’un autre rapport à l’idéologie vient alors prendre le relais de la lutte anti-idéologique de la théorie critique. Cette recherche part du po...

  16. Article n_TOF : rectificatif

    CERN Multimedia

    2008-01-01

    Une erreur s’est malencontreusement glissée dans la version française de la dernière édition du Bulletin papier. L’introduction (en gras) de l’article « Les neutrons sur la piste de décollage » était celle de l’article sur le Linac 4 paru dans l’édition précédente. Le paragraphe correct est le suivant : « Au repos depuis quatre ans, les neutrons volent à nouveau dans l’installation n_TOF (mesure du temps de vol des neutrons), qui vient d’être remise en service avec une nouvelle cible. » Veuillez nous excuser pour cette erreur.

  17. The national identity politics of Danish humanitarianism

    DEFF Research Database (Denmark)

    Christiansen, Lene Bull

    and proposes to look beyond the mainstream US/UK contexts in order to make this point. The paper takes point of departure in the annual Danish aid telethon Danmarks Indsamling (Denmark’s Collection). Against the backdrop of the local identity politics in Denmark revolving around immigration policies...... of a collective identity narrative are seen to draw on the above-mentioned gendered and colonialist discourses while simultaneously engaging in local politics around diversity and national identity......., 2009; Jefferess, 2002; Repo and Yrjölä, 2011). While these studies provide important insights, another side remains – that of collective identity narratives associated with humanitarian appeals. This paper posits that collective identity narratives have a vital importance in many humanitarian appeals...

  18. Modeling of the pollutant transport in fissured-porous media under consideration of colloids using the transport codes FRAME and COFRAME; Modellierung des Schadstofftransports in geklueftet-poroesen Medien unter Beruecksichtigung von Kolloiden mit den Transportprogrammen FRAME und COFRAME

    Energy Technology Data Exchange (ETDEWEB)

    Reiche, Tatiana; Noseck, Ulrich; Wolf, Jens Wilhelm

    2014-05-15

    For the long-term safety analysis of final nuclear waste repositories the transport of pollutants from the repository into the biosphere three mostly independent subsystems are considered: the near field, the geosphere and the biosphere. Normally rocks include fissures or other disturbances. Porous materials in the rock matrix have usually a high water content and acts as storage for pollutants due to sorption and diffusion processes. The aim of the project is the development of calculation modules for the code RepoTREND that simulate the pollutant transport in saturated fissured-porous media taking into account the effect of colloids. FRAME describes the pollutant dispersion in a fissured-porous medium and COFRAME the colloid influenced transport in a fissured-porous medium.

  19. Lille – 28-30 rue des Fossés

    OpenAIRE

    Blieck, Gilles

    2013-01-01

    Date de l'opération : 1991 (SP) Inventeur(s) : Blieck Gilles Cette intervention sur un terrain attenant constituait le second volet de l’opération de la place Rihour [ (Fig. n°1 : Plan général. Localisation des zones fouillées), site I]. Elle a permis de compléter les observations précédentes notamment en ce qui concerne la genèse de cette fortification. La défense paraît avoir reposé, dans un premier temps, sur un simple fossé de 8,50 m de large sur 1,10 m de profondeur. Le débordement régu...

  20. A epigenética das infeções nosocomiais

    OpenAIRE

    Ribeiro, Edna

    2017-01-01

    Definição de epigenética: “adaptação estrutural de regiões de cromossomas que permitem registar, sinalizar ou perpetuar estados de actividade alterados”. A epigenética permite a diferenciação celular em células de tecidos com a mesma informação genética através da alteração hereditária de expressão de genes ou fenótipos que não envolvem alterações na sequência de DNA. info:eu-repo/semantics/publishedVersion

  1. Accelerating Inspire

    CERN Document Server

    AUTHOR|(CDS)2266999

    2017-01-01

    CERN has been involved in the dissemination of scientific results since its early days and has continuously updated the distribution channels. Currently, Inspire hosts catalogues of articles, authors, institutions, conferences, jobs, experiments, journals and more. Successful orientation among this amount of data requires comprehensive linking between the content. Inspire has lacked a system for linking experiments and articles together based on which accelerator they were conducted at. The purpose of this project has been to create such a system. Records for 156 accelerators were created and all 2913 experiments on Inspire were given corresponding MARC tags. Records of 18404 accelerator physics related bibliographic entries were also tagged with corresponding accelerator tags. Finally, as a part of the endeavour to broaden CERN's presence on Wikipedia, existing Wikipedia articles of accelerators were updated with short descriptions and links to Inspire. In total, 86 Wikipedia articles were updated. This repo...

  2. Factors Impacting Bank Net Interest Margin and the Role of Monetary Policy: Evidence from Turkey

    Directory of Open Access Journals (Sweden)

    Muhammed Hasan Yılmaz

    2017-10-01

    Full Text Available In this study, we investigate factors affecting net interest margin (NIM of commercial banks in Turkey. Especially, our results highlight the relation between unconventional monetary policy shocks and bank margins. To this end, first, we conduct an identification analysis about which parameters of asymmetric interest corridor framework are important in explaining variations in NIM. Using industry-level data, we show that there exists a pass through from BIST interbank overnight repo/reverse repo market rate and weighted average cost of funding (WACF to bank loan and deposit rates. As a result of reduced-form Vector Autoregression (VAR analysis we find the existence of a transmission mechanism from BIST rate and WACF to commercial loan rate, consumer loan rate and deposit rate. Same pass through to loan and deposit rates is also shown in individual bank level with the Panel Vector Autoregression (Panel VAR analysis in the case of 16 commercial banks in Turkey during the period 2011Q1-2016Q1. After the identification analysis, we examine the relationship between NIM and policy rates through System Generalized Method of Moments (GMM techniques by controlling bank specific, industry related and macroeconomic factors. We find that a change in the monetary policy rate has significant and positive impact on NIM. Among bank-specific factors, equity ratio and operating expenses are found to be significantly affecting NIM during the sample period. Our empirical findings also stress the significance of lag values of NIM. Estimations conducted with standardized variables indicate that economic significance of lag values and bank specific variables are larger than that of policy.

  3. The glucuronyltransferase GlcAT-P is required for stretch growth of peripheral nerves in Drosophila.

    Directory of Open Access Journals (Sweden)

    Rahul Pandey

    Full Text Available During development, the growth of the animal body is accompanied by a concomitant elongation of the peripheral nerves, which requires the elongation of integrated nerve fibers and the axons projecting therein. Although this process is of fundamental importance to almost all organisms of the animal kingdom, very little is known about the mechanisms regulating this process. Here, we describe the identification and characterization of novel mutant alleles of GlcAT-P, the Drosophila ortholog of the mammalian glucuronyltransferase b3gat1. GlcAT-P mutants reveal shorter larval peripheral nerves and an elongated ventral nerve cord (VNC. We show that GlcAT-P is expressed in a subset of neurons in the central brain hemispheres, in some motoneurons of the ventral nerve cord as well as in central and peripheral nerve glia. We demonstrate that in GlcAT-P mutants the VNC is under tension of shorter peripheral nerves suggesting that the VNC elongates as a consequence of tension imparted by retarded peripheral nerve growth during larval development. We also provide evidence that for growth of peripheral nerve fibers GlcAT-P is critically required in hemocytes; however, glial cells are also important in this process. The glial specific repo gene acts as a modifier of GlcAT-P and loss or reduction of repo function in a GlcAT-P mutant background enhances VNC elongation. We propose a model in which hemocytes are required for aspects of glial cell biology which in turn affects the elongation of peripheral nerves during larval development. Our data also identifies GlcAT-P as a first candidate gene involved in growth of integrated peripheral nerves and therefore establishes Drosophila as an amenable in-vivo model system to study this process at the cellular and molecular level in more detail.

  4. The glucuronyltransferase GlcAT-P is required for stretch growth of peripheral nerves in Drosophila.

    Science.gov (United States)

    Pandey, Rahul; Blanco, Jorge; Udolph, Gerald

    2011-01-01

    During development, the growth of the animal body is accompanied by a concomitant elongation of the peripheral nerves, which requires the elongation of integrated nerve fibers and the axons projecting therein. Although this process is of fundamental importance to almost all organisms of the animal kingdom, very little is known about the mechanisms regulating this process. Here, we describe the identification and characterization of novel mutant alleles of GlcAT-P, the Drosophila ortholog of the mammalian glucuronyltransferase b3gat1. GlcAT-P mutants reveal shorter larval peripheral nerves and an elongated ventral nerve cord (VNC). We show that GlcAT-P is expressed in a subset of neurons in the central brain hemispheres, in some motoneurons of the ventral nerve cord as well as in central and peripheral nerve glia. We demonstrate that in GlcAT-P mutants the VNC is under tension of shorter peripheral nerves suggesting that the VNC elongates as a consequence of tension imparted by retarded peripheral nerve growth during larval development. We also provide evidence that for growth of peripheral nerve fibers GlcAT-P is critically required in hemocytes; however, glial cells are also important in this process. The glial specific repo gene acts as a modifier of GlcAT-P and loss or reduction of repo function in a GlcAT-P mutant background enhances VNC elongation. We propose a model in which hemocytes are required for aspects of glial cell biology which in turn affects the elongation of peripheral nerves during larval development. Our data also identifies GlcAT-P as a first candidate gene involved in growth of integrated peripheral nerves and therefore establishes Drosophila as an amenable in-vivo model system to study this process at the cellular and molecular level in more detail.

  5. Polycythemia is associated with bone loss and reduced osteoblast activity in mice.

    Science.gov (United States)

    Oikonomidou, P R; Casu, C; Yang, Z; Crielaard, B; Shim, J H; Rivella, S; Vogiatzi, M G

    2016-04-01

    Increased fragility has been described in humans with polycythemia vera (PV). Herein, we describe an osteoporotic phenotype associated with decreased osteoblast activity in a mouse model of PV and another mouse of polycythemia and elevated circulating erythropoietin (EPO). Our results are important for patients with PV or those treated with recombinant EPO (rEPO). PV and other myeloproliferative syndromes have been recently associated with an increased risk for fractures. However, the presence of osteoporosis in these patients has not been well documented. EPO, a hormone primarily known to stimulate erythropoiesis, has been shown recently to regulate bone homeostasis in mice. The aim of this study was to examine the bone phenotype of a mouse model of PV and compare it to that of animals with polycythemia caused by elevated circulating EPO. Bone mass and remodeling were evaluated by micro-computed tomography and histomorphometry. The JAK2(V617F) knock-in mouse, a model of human PV, manifests polycythemia and low circulating EPO levels. Results from this mouse were compared to wild type (wt) controls and the tg6 transgenic mouse that shows polycythemia caused by increased constitutive expression of EPO. Compared to wt, both JAK2(V617F) and tg6 mice had a decrease in trabecular bone mass. Tg6 mice showed an additional modest decrease in cortical thickness and cortical bone volume per tissue volume (P Polycythemia caused by chronically elevated circulating EPO also results in bone loss, and implications on patients treated with rEPO should be evaluated.

  6. Coolability of a 3D homogeneous debris bed, experimental and numerical investigations

    International Nuclear Information System (INIS)

    Atkhen, K.; Berthoud, G.

    2001-01-01

    Within the framework of nuclear safety analysis, we present here experimental and numerical results in the field of debris bed coolability. Experimental data are provided by the SILFIDE 3D experimental facility in which the debris bed is heated by induction, at Electricite de France (EDF). Numerical computations are obtained with MC3D-REPO which is a 3-phase and 3D code developed by the Commissariat a l'Energie Atomique (CEA). The uniform debris bed consists of 2 and 3,17 mm diameter steel beads contained in a 50 cm x 60 cm x 10 cm vessel. Water is used as a coolant and can be introduced either by the top or the bottom of the bed at a determined temperature. Due to heterogeneous power distribution within the bed, two definitions for the critical heat flux are proposed: the classical mean value and the local flux (much higher). Even in the first case, the measured dryout heat flux is higher than the Lipinsky 1-D flux. Temperature curve analyses show that the dryout phenomenon is very local, therefore one should be careful about the right flux definition to use. As the injected power is being increased stepwise, steady temperature stages above saturation temperature before dryout can be observed. A discussion is proposed. For some very high values of the induction power, some spheres melted together, leading to a bigger non-porous region. Even if the local temperature went over 1300 C, the bed was still coolable and the critical heat flux value was not impacted. Some parametric studies led to the following conclusions: bottom coolant injection leads to a twice time higher critical flux than by top injection, the influence of the height of the water pool above debris bed is negligible, a sub-cooled liquid injection has no influence on the coolability. Fluidization of surface particles is also discussed. The MC3D-REPO model assumes a thermal equilibrium between the three phases, which gives results in agreement with experiments until dryout occurs. (author)

  7. submitter 16 T Nb$_{3}$Sn Racetrack Model Coil Test Result

    CERN Document Server

    Perez, J C; Bajko, M; Bottura, L; Bordini, B; Chiuchiolo, A; De Rijk, G; Ferracin, P; Feuvrier, J; Grosclaude, P; Juchno, M; Rochepault, E; Rysti, J; Sarasola, X

    2016-01-01

    In the framework of the European project EuCARD, the High Field Magnet project, led by a CERN-CEA collaboration, implied the development of a large aperture Nb$_{3}$Sn dipole magnet called FRESCA2. The magnet uses four double-pancake block-type coils, each about 1.5 m long. In order to characterize strand and cable properties, as well as to qualify the coil fabrication process, CERN started in 2012 the design and fabrication of the Racetrack Model Coil (RMC) magnet, a short model magnet using the same cable as FRESCA2 magnet with only two flat double-pancake coils about 0.8 m long. In 2013, two superconducting coils have been fabricated, making use of two different types of superconductor. In 2014 and 2015, the coils were tested both in a single and in a double-coil configuration in a support structure based on an external aluminum shell pre-loaded with water-pressurized bladders. In this paper, we describe the design of the RMC magnet and its coils, provide the main parameters of the superconductor, and repo...

  8. Present condition and the future of photovoltaic generating systems. Part 5. Future perspective of photovoltaic power systems; Taiyo hikarihatsuden system no genjo to shorai. 5. Taiyo hikarihatsuden system no shorai tenbo

    Energy Technology Data Exchange (ETDEWEB)

    Horigome, T

    1994-12-20

    In this paper, as the future perspective of photovoltaic power systems, the establishment of the legal environment for the popularization of the photovoltaic power systems in large amounts and the future prediction of the popularization of power generation are described. Specially the following grand ideas are introduced: building in high seas regeneratable energy transformation plants with solar energy as the main energy, generating combined power of photovoltaic, solar heat, wave and temperature difference of the sea water, biomass, solar-bio power generating without CO2 exhaustion, building hard solar plants to produce electricity, hydrogen, methanol and fresh water from regeneratable energy, and breeding fish, shells and see weed in the sea pasture land under the plants, which are the so called `Energy sea pasture high breed plants (REPO Plan)` and also space power generating i.e. setting up special satellites for solar power generation in synchronous orbits, generating power through solar batteries or solar heat and then transmitting it to the earth through microwave. 12 refs., 4 figs.

  9. Sélection et utilisation de l'habitat par les jeunes stades de poissons d'eau courante : le modèle Ombre commun (Thymallus thymallus, L.

    Directory of Open Access Journals (Sweden)

    SEMPESKI P.

    1995-04-01

    Full Text Available L'Ombre commun a servi de modèle biologique dans le cadre de l'étude de la dynamique des changements d'habitats caractérisant les jeunes stades de poissons d'eau courante. Des campagnes d'observations directes, depuis la berge ou en plongée, de jour comme de nuit, associées à des descriptions de l'habitat physique et des prélèvements de poissons et de faune invertébrée benthique et dérivante, ont permis une analyse fine de la sélection et de l'utilisation de l'habitat par les jeunes stades d'ombre et de leur évolution à différentes échelles spatio-temporelles. Différents groupes fonctionnels ont pu être distingués parmi les stades larvaires et juvéniles, en fonction des microhabitats sélectionnés de jour (alimentation et de nuit (repos, et des différentes stratégies de sélection des proies.

  10. Romanian government bond market

    Directory of Open Access Journals (Sweden)

    Cornelia POP

    2012-12-01

    Full Text Available The present paper aims to present the level of development reached by Romanian government bond market segment, as part of the country financial market. The analysis will be descriptive (the data series available for Romania are short, based on the secondary data offered by the official bodies involved in the process of issuing and trading the Romanian government bonds (Romanian Ministry of Public Finance, Romanian National Bank and Bucharest Stock Exchange, and also on secondary data provided by the Federation of European Stock Exchanges.To enhance the market credibility as a benchmark, a various combination of measures is necessary; among these measures are mentioned: the extension of the yield curve; the issuance calendars in order to improve transparency; increasing the disclosure of information on public debt issuance and statistics; holding regular meetings with dealers, institutional investors and rating agencies; introducing a system of primary dealers; establishing a repurchase (repo market in the government bond market. These measures will be discussed based on the evolution presented inside the paper.The paper conclude with the fact that, until now, the Romanian government bond market did not provide a benchmark for the domestic financial market and that further efforts are needed in order to increase the government bond market transparency and liquidity.

  11. Hommage

    CERN Document Server

    Marcel (Aymon)

    2012-01-01

    Jean-Paul DISS Docteur en Médecine 1928 - 2012 Hommage à l’ami Jean-Paul C'est avec une profonde émotion et grande tristesse que nous avons appris, voici quelques jours, le décès subit de notre cher collègue et ami Jean-Paul Diss. Il n'était pas physicien, ni ingénieur, mais médecin. Et pourtant, il faisait partie des pionniers de notre Organisation, un de ceux à qui nous devons notre prospérité d'aujourd'hui. Jean-Paul était né en Alsace en septembre 1928. Autant dire que sa jeunesse n'a pas dû être de tout repos, car les années noires de la guerre faisaient alors rage, surtout dans sa région. Plus tard, après ses études et diverses occupations, il avait rejoint l'Organisation en juin 1965 pour créer et organiser le S...

  12. Time and frequency structure of causal correlation networks in the China bond market

    Science.gov (United States)

    Wang, Zhongxing; Yan, Yan; Chen, Xiaosong

    2017-07-01

    There are more than eight hundred interest rates published in the China bond market every day. Identifying the benchmark interest rates that have broad influences on most other interest rates is a major concern for economists. In this paper, a multi-variable Granger causality test is developed and applied to construct a directed network of interest rates, whose important nodes, regarded as key interest rates, are evaluated with CheiRank scores. The results indicate that repo rates are the benchmark of short-term rates, the central bank bill rates are in the core position of mid-term interest rates network, and treasury bond rates lead the long-term bond rates. The evolution of benchmark interest rates from 2008 to 2014 is also studied, and it is found that SHIBOR has generally become the benchmark interest rate in China. In the frequency domain we identify the properties of information flows between interest rates, and the result confirms the existence of market segmentation in the China bond market.

  13. Connexin Hemichannels in Astrocytes

    DEFF Research Database (Denmark)

    Nielsen, Brian Skriver; Hansen, Daniel Bloch; Ransom, Bruce R.

    2017-01-01

    Astrocytes in the mammalian central nervous system are interconnected by gap junctions made from connexins of the subtypes Cx30 and Cx43. These proteins may exist as hemichannels in the plasma membrane in the absence of a ‘docked’ counterpart on the neighboring cell. A variety of stimuli are repo...... selectivity. We expect that some, or all, of the controversies discussed here will be resolved by future research and sincerely hope that this review serves to motivate such clarifying investigations.......Astrocytes in the mammalian central nervous system are interconnected by gap junctions made from connexins of the subtypes Cx30 and Cx43. These proteins may exist as hemichannels in the plasma membrane in the absence of a ‘docked’ counterpart on the neighboring cell. A variety of stimuli....... Published studies about astrocyte hemichannel behavior, however, have been highly variable and/or contradictory. The field of connexin hemichannel research has been complicated by great variability in the experimental preparations employed, a lack of highly specific pharmacological inhibitors...

  14. Orienteering club

    CERN Multimedia

    Orienteering Club

    2016-01-01

    Course d'orientation Calendrier des courses d’orientation Coupe genevoise d’automne 2016 Samedi 3 septembre : La Faucille (01) Samedi 10 septembre : Prémanon (39) Samedi 17 septembre : Saint-Cergue (VD) Samedi 24 septembre : Jorat / Corcelles (VD) Samedi 1 octobre: Bière - Ballens (VD) -relais Vendredi 14 octobre : Parc Mon Repos (GE) - nocturne Samedi 15 octobre : Terrasse de Genève (74) Samedi 29 octobre : Bonmont (VD) Samedi 5 novembre : Pomier (74) – one-man-relay - Finale   Courses ouvertes à toutes et à tous, sportifs, familles, débutants ou confirmés, du CERN ou d’ailleurs. Cinq circuits disponibles, ceci va du facile court (2 km) adapté aux débutants et aux enfants jusqu’au parcours technique long de 6 km pour les chevronnés en passant par les parcours facile moyen (4&am...

  15. Thousands of men in four Latin countries choose to have vasectomies; machismo is no barrier.

    Science.gov (United States)

    1975-12-01

    The acceptability of vasectomy in 4 Latin American countries is repo rted. The unenthusiastic reception of vasectomy in Latin America is apparently due to a paucity of male sterilization programs and not to machismo. The 1st vasectomy program in Latin America was established in Bogota, Colombia, in 1970. This was followed by programs in Costa Rica (1971), El Salvador (1972), and Guatemala (1973). Upon expansion of the Colombian program from 1 city to 9 cities, the number of voluntary vasectomies increased from 100 to 560. 235 vasectomies were performed in the 1st 6 months of the Costa Rican program, and 278 were performed in the 1st 9 months of the Guatemalan program. During the 1st 2 years of the program in El Salvador, the monthly average of operations performed rose from 3 to 19. In El Salvador at least, vasectomy was acceptable to men aged 22-69 years, with 2-20 living children, and from all types of occupations.

  16. The usage of financial derivatives in financial risk management by non- financial companies in Serbia

    Directory of Open Access Journals (Sweden)

    Živanović Branko

    2017-01-01

    Full Text Available In this paper we analyse the research results on corporate risk management practices, notably in light of the derivatives use in the large Serbian non-financial companies. The principal aim of this paper is to examine whether Serbian companies employ derivatives to manage risk and to what degree, and to explore the main rationale behind the companies' not employing these instruments, as well as to suggest possible enhancements of risk management practices. Furthermore, we have investigated the key reasons why financial derivatives are very useful for Serbian companies for hedging financial risks. Additionally, this paper provides a comparative overview of the use of derivatives between Serbian companies and the companies in Croatia and Slovenia in order to ascertain whether Serbian companies employ derivatives in order to manage risk to the same degree as their Croatian and Slovenian counterparts. This paper will include findings and provide evidence that FX rate and referent interest rates (such as 1w- 2w repo rate, Beonia and Belibor are markedly volatile, which opens vast possibilities for the use of financial derivatives, given that these financial parameters determine the price of a credit arrangement for companies and the quality of import and export cash flows.

  17. Eksperimen Seleksi Fitur Pada Parameter Proyek Untuk Software Effort Estimation dengan K-Nearest Neighbor

    Directory of Open Access Journals (Sweden)

    Fachruddin Fachruddin

    2017-07-01

    Full Text Available Software Effort Estimation adalah proses estimasi biaya perangkat lunak sebagai suatu proses penting dalam melakukan proyek perangkat lunak. Berbagai penelitian terdahulu telah melakukan estimasi usaha perangkat lunak dengan berbagai metode, baik metode machine learning  maupun non machine learning. Penelitian ini mengadakan set eksperimen seleksi atribut pada parameter proyek menggunakan teknik k-nearest neighbours sebagai estimasinya dengan melakukan seleksi atribut menggunakan information gain dan mutual information serta bagaimana menemukan  parameter proyek yang paling representif pada software effort estimation. Dataset software estimation effort yang digunakan pada eksperimen adalah  yakni albrecht, china, kemerer dan mizayaki94 yang dapat diperoleh dari repositori data khusus Software Effort Estimation melalui url http://openscience.us/repo/effort/. Selanjutnya peneliti melakukan pembangunan aplikasi seleksi atribut untuk menyeleksi parameter proyek. Sistem ini menghasilkan dataset arff yang telah diseleksi. Aplikasi ini dibangun dengan bahasa java menggunakan IDE Netbean. Kemudian dataset yang telah di-generate merupakan parameter hasil seleksi yang akan dibandingkan pada saat melakukan Software Effort Estimation menggunakan tool WEKA . Seleksi Fitur berhasil menurunkan nilai error estimasi (yang diwakilkan oleh nilai RAE dan RMSE. Artinya bahwa semakin rendah nilai error (RAE dan RMSE maka semakin akurat nilai estimasi yang dihasilkan. Estimasi semakin baik setelah di lakukan seleksi fitur baik menggunakan information gain maupun mutual information. Dari nilai error yang dihasilkan maka dapat disimpulkan bahwa dataset yang dihasilkan seleksi fitur dengan metode information gain lebih baik dibanding mutual information namun, perbedaan keduanya tidak terlalu signifikan.

  18. Repositioning of Barcelona's Image in the Light of a Redefinition of the Urban Tourism Planning Model

    Directory of Open Access Journals (Sweden)

    Josep-Francesc Valls

    2013-01-01

    Full Text Available El modelo de desarrollo urbanístico-turístico de Barcelona en los últimos quince años ha obtenido un éxito extraordinario en cuanto a número de visitantes, pernoctaciones, llegadas de pasajeros de cruceros, incremento de camas hoteleras y visitas a monumentos de pago. De este modo, la ciudad se ha convertido en una de las ciudades más visitadas de Europa y de mayor crecimiento del número de turistas. Pero, este crecimiento cuantitativo ha generado masificación turística, concentración en determinados barrios, enfrentamiento por el uso del espacio urbano entre turistas y residentes, además de generar algunas deficiencias infraestructurales como la conectividad y la intermodalidad. Estos problemas amenazan la posición competitiva de Barcelona. Este artículo revisa la competitividad entre las ciudades, comparando Barcelona con otras diez ciudades europeas. A partir de un análisis cualitativo a los players internos y externos y de un Estudio Delphi con players externos, se exploran las correcciones que hay que introducir en el modelo y los vectores del repo- sicionamiento. Esta nueva posición refuerza la competitividad en base a tres objetivos: la sostenibilidad del modelo, la gestión integral de la metrópolis turística y su gobernanza, y la orientación al cliente.

  19. Foreword

    Science.gov (United States)

    Zoupanos, G.

    These are the Proceedings of the scientific activities of CORFU2016, the 16th Hellenic School and Workshops on Elementary Particle Physics and Gravity, which took place from August 31st till September 23rd, 2016. The School and Workshops were hosted by the European Institute for Sciences and their Applications (EISA) at the conference center of the ex-Royal Palace garden of Mon Repos in Corfu, Greece. The scientific activities consisted of a series of three events, the Summer School and Workshop on the Standard Model and Beyond, the Recent Developments in Strings and Gravity, the ATLAS Hadronic Calibration Workshop 2016 and a rich set of outreach activities ( TV and radio interviews, Master Classes, series of lectures to High School teachers and talks for the public). We refer to the website www.physics.ntua.gr/corfu2016 for the various organizational and practical details. These proceedings are dedicated to our beloved friend and colleague Giannis (Ioannis) Bakas who passed away on Tuesday, Aug 30, 2016.

  20. Simplified method for the determination of strontium-90 in large amounts of bone-ash; Methode simplifiee de dosage du strontium 90 sur des quantites importantes de cendres d'os

    Energy Technology Data Exchange (ETDEWEB)

    Patti, F; Jeanmaire, L [Commissariat a l' Energie Atomique, Fontenay-aux-roses (France). Centre d' Etudes Nucleaires

    1966-06-01

    The principle of the determination is based on a 3-step process: 1) concentrating the strontium by attacking the ash with nitric acid; 2) elimination of residual phosphoric ions by a double precipitation of strontium oxalate; and 3) extraction of yttrium 90, counted in the oxalate form. The advantages of the method: -) using simple techniques it makes it possible to process 50 g of ash; -) the initial concentration of strontium considerably reduces the volume of the solutions as well as the size of precipitates handled. Fuming nitric acid is used in a specially designed burette. (authors) [French] Le principe du dosage repos sur un procede en 3 etapes: 1) Concentration du strontium par une attaque nitrique des cendres; 2) Elimination des ions phosphoriques restants par une double precipitation de l'oxalate de strontium. 3) Extraction de l'yttrium 90, compte sous forme d'oxalate. Interet de la methode: dans des conditions techniques simples, elle permet le traitement de 50 g de cendres d'os; la concentration initiale du strontium reduit notablement le volume des solutions ainsi que l'importance des precipites manipules. L'acide nitrique fumant est utilise par l'intermediaire d'une burette specialement concue a cet effet.

  1. The Serial Link Processor for the Fast TracKer (FTK) processor at ATLAS

    CERN Document Server

    Andreani, A; The ATLAS collaboration; Beccherle, R; Beretta, M; Cipriani, R; Citraro, S; Citterio, M; Colombo, A; Crescioli, F; Dimas, D; Donati, S; Giannetti, P; Kordas, K; Lanza, A; Liberali, V; Luciano, P; Magalotti, D; Neroutsos, P; Nikolaidis, S; Piendibene, M; Sakellariou, A; Shojaii, S; Sotiropoulou, C-L; Stabile, A

    2014-01-01

    The Associative Memory (AM) system of the FTK processor has been designed to perform pattern matching using the hit information of the ATLAS silicon tracker. The AM is the heart of the FTK and it finds track candidates at low resolution that are seeds for a full resolution track fitting. To solve the very challenging data traffic problems inside the FTK, multiple designs and tests have been performed. The currently proposed solution is named the “Serial Link Processor” and is based on an extremely powerful network of 2 Gb/s serial links. This paper reports on the design of the Serial Link Processor consisting of the AM chip, an ASIC designed and optimized to perform pattern matching, and two types of boards, the Local Associative Memory Board (LAMB), a mezzanine where the AM chips are mounted, and the Associative Memory Board (AMB), a 9U VME board which holds and exercises four LAMBs. Special relevance will be given to the AMchip design that includes two custom cells optimized for low consumption. We repo...

  2. Credit Spread Modeling: Macro-financial versus HOC Approach

    Directory of Open Access Journals (Sweden)

    Sanja Dudaković

    2014-12-01

    Full Text Available The aim of this paper is to throw light on the relationship between credit spread changes and past changes of U.S. macro-financial variables when invariants do not have Gaussian distribution. The first part presents the empirical analysis which is based on 10-year AAA corporate bond yields and 10-year Treasury bond yields. Explanatory variables include lagged U.S. leading index, Russell 2000 returns, BBB bond price changes interest rate swaps, exchange rates EUR/ USD, Repo rates, S& P 500 returns and S&P 500 volatility, Treasury bill changes, liquidity index-TRSW, LIBOR rates, Moody’s default rates; credit spread volatility and Treasury bills volatility. The proposed dynamical model explains 73% of the U.S. credit spread variance for the period 1999:07-2013:07. The second part of the article introduces the parameter estimation method based on higher order cumulants. It is demonstrated empirically that much of the information about variability of Credit Spread can be extracted from higher order cumulant function (85%.

  3. Predictive factors for homologous transfusion during paediatric scoliosis surgery.

    Science.gov (United States)

    Dupuis, Claire; Michelet, Daphné; Hilly, Julie; Diallo, Thierno; Vidal, Christophe; Delivet, Honorine; Nivoche, Yves; Mazda, Keyvan; Dahmani, Souhayl

    2015-12-01

    Blood saving strategies during paediatric spinal surgery often include recombinant erythropoietin (rEPO) and antifibrinolytic therapy (AFT). The goal of this study was to investigate additional preventive factors involved in the risk of blood transfusion. This prospective study was designed with the aim of identifying factors associated with the perioperative (defined as the intraoperative and the first postoperative day) probability of homologous red cell transfusion during scoliosis surgery in children operated during a one year period in our institution. The predictors analysed were: age, weight less than the 3rd percentile (W 255 minutes. ROC analysis for the latter model found an area under the curve of 0.9 (95% confidence interval: 0.8-0.97). The accuracy of the model was 92.3% (97.4% for non-transfusion and 69.2% for transfusion). Multivariate sensitivity analysis excluding patients with no preoperative administration of EPO found similar results. The current results indicate that optimising nutritional status might prevent allogenic blood transfusion and requires further investigation. Copyright © 2015 Société française d’anesthésie et de réanimation (Sfar). Published by Elsevier Masson SAS. All rights reserved.

  4. DIMAC program user's manual

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byoung Oon; Song, Tae Young

    2003-11-01

    DIMAC (A DIspersion Metallic fuel performance Analysis Code) is a computer program for simulating the behavior of dispersion fuel rods under normal operating conditions of HYPER. It computes the one-dimensional temperature distribution and the thermo-mechanical characteristics of fuel rod under the steady state operation condition, including the swelling and rod deformation. DIMAC was developed based on the experience of research reactor fuel. DIMAC consists of the temperature calculation module, the mechanical swelling calculation module, and the fuel deformation calculation module in order to predict the deformation of a dispersion fuel as a function of power history. Because there are a little of available U-TRU-Zr or TRU-Zr characteristics, the material data of U-Pu-Zr or Pu-Zr are used for those of U-TRU-Zr or TRU-Zr. This report is mainly intended as a user's manual for the DIMAC code. The general description on this code, the description on input parameter, the description on each subroutine, the sample problem and the sample input and partial output are written in this repo0008.

  5. Effect of Al{sup 3+} ions on fluorescence properties of Eu{sup 3+} ions in YPO{sub 4} phosphors

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Dong Woo; Balakrishnaiah, R.; Yi, Soung Soo [Silla Univ., Busan (Korea, Republic of); Balakrishnaiah, R.; Jang, Kiwan; Lee, Ho Sueb [Changwon National Univ., Changwon (Korea, Republic of); Jeong, Jung Hyun [PUkyong National Univ., Busan (Korea, Republic of)

    2008-11-15

    Lanthanide(Ln)doped materials find potential applications in the fields of lasers, optical amplifiers, phosphors, display devices, etc., due to their characteristic energy level schemes. These materials found wide useful in the development of plasma display panels(PDP), field emission displays(FED)and electro luminescent panel applications. Recently, REPO{sub 4}(RE=Y, La, Gd, Lu)materials have attracted much attention in PDP applications due to their high thermal and chemical stability as well as high luminescence efficiency under VUV excitation. Tricolor inorganic luminescence materials are used in PDP to emit red, green and blue light. PDP phosphors emit visible light under VUV excitation. The VUV pump photon is absorbed by the host lattice and color purity are most essential. It is thus necessary either to further improve the luminescence properties, or to develop new phosphors. It is possible to tune the intensity of red emission by modifying the neighboring network design around Eu{sup 3+} ions on introducing other atoms such as Ca, Sr, Ba, Zn, Al, Li, Sc, Bi, La, Gd, etc., into the ortho phosphate host lattice. The prepared samples are characterized by XRD, SEM, photoluminescence excitation, photoluminescence emission and lifetime measurements. The results are also compared with those of earlier reported works.

  6. HappyFace as a monitoring tool for the ATLAS experiment

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00367045; Yahyapour, Ramin

    The importance of monitoring on HEP grid computing systems is growing due to a significant increase in their complexity. Computer scientists and administrators have been studying and building effective ways to gather information on and clarify a status of each local grid infrastructure. The HappyFace project aims at making the above-mentioned workflow possible. It aggregates, processes and stores the informa- tion and the status of different HEP monitoring resources into the common database of HappyFace. The system displays the information and the status through a single interface. However, this model of HappyFace relied on the monitoring resources which are al- ways under development in the HEP experiments. Consequently, HappyFace needed to have direct access methods to the grid application and grid service layers in the dif- ferent HEP grid systems. To cope with this issue, we use a reliable HEP software repos- itory, the CernVM File System. We propose a new implementation and an architecture of HappyFace, ...

  7. PipelineDog: a simple and flexible graphic pipeline construction and maintenance tool.

    Science.gov (United States)

    Zhou, Anbo; Zhang, Yeting; Sun, Yazhou; Xing, Jinchuan

    2018-05-01

    Analysis pipelines are an essential part of bioinformatics research, and ad hoc pipelines are frequently created by researchers for prototyping and proof-of-concept purposes. However, most existing pipeline management system or workflow engines are too complex for rapid prototyping or learning the pipeline concept. A lightweight, user-friendly and flexible solution is thus desirable. In this study, we developed a new pipeline construction and maintenance tool, PipelineDog. This is a web-based integrated development environment with a modern web graphical user interface. It offers cross-platform compatibility, project management capabilities, code formatting and error checking functions and an online repository. It uses an easy-to-read/write script system that encourages code reuse. With the online repository, it also encourages sharing of pipelines, which enhances analysis reproducibility and accountability. For most users, PipelineDog requires no software installation. Overall, this web application provides a way to rapidly create and easily manage pipelines. PipelineDog web app is freely available at http://web.pipeline.dog. The command line version is available at http://www.npmjs.com/package/pipelinedog and online repository at http://repo.pipeline.dog. ysun@kean.edu or xing@biology.rutgers.edu or ysun@diagnoa.com. Supplementary data are available at Bioinformatics online.

  8. Características morfofisiológicas asociadas con el rendimiento del café Morphological and physiological characteristics associated with yield in coffee trees

    Directory of Open Access Journals (Sweden)

    Salazar Jose Nestor

    1988-12-01

    Full Text Available Un experimento de campo se llevó a cabo para analizar y comparar el efecto de algunas características morfofisiológicas sobre el rendimiento de 5 variedades de café de porte bajo en condiciones de alta densidad de siembra. Las variedades utilizadas fueron: Colombia, Caturra, Catuai, Caturra erecta y Caturra X San Bernardo. La variedad Colombia presentó el mayor número de ramas primarias y productivas por árbol y de nudos productivos por rama. Las variedades Caturra, Catuai y Caturra erecta reportaron el mayor número de frutos por nudo. El más alto rendimiento lo obtuvo la variedad Colombia con 7321 kg de café pergamino seco/ha/año aunque este valor no fue significativamente diferente de los promedios mostrados por las variedades Caturra y Catuai.A field experiment was conducted to analyze and compare the effect of some morphological characteristics on 5 shortstature
    coffe varieties under high tree density conditions. The varieties used were Colombia, Caturra, Catuai, Caturra erecta and Caturra X San Bernardo. The variety Colombia showed the highest values for primary and productive branches per tree and for productive nodes per branch. The varieties Caturra, Catuai and Caturra erecta obtained the greatest number of fruits par node. The highest yield of 7321 kg fresh berries/ha/year was repo rted by Colombia eventhough this value was not significantly different from those obtained by Caturra and Catuai.

  9. Monetary policy and insolvency of economic sector

    Directory of Open Access Journals (Sweden)

    Tepavac Rajko

    2012-03-01

    Full Text Available The main task of monetary policy of our central bank is to achieve and preserve stability of prices and currency. Targeted inflation rate has been chosen as operating instrument for gradual realization of low and stable inflation, along with elimination of inflation expectations. Also, a specific inflation corridor is chosen to ensure operations, transparency and ex ante effects of monetary policy. The paper presents analysis on whether there really is a restrictive monetary policy, deflections of real inflation from the programmed one, level of 'restrictiveness' of monetary policy and behavior of bank loans, money supply, nominal and real economic growth. Analysis is carried out and criticism of concepts of monetary regulation of mandatory bank reserves, blocking of financial bank potential through monetary regulation instruments, but also relations between central and business banks through open market policy. Criticism of repo operations and complete disappearance of selective credit policy is provided as well. The problem of almost embedded insolvency of economic sector is highlighted.

  10. Continuous Integration for Concurrent MOOSE Framework and Application Development on GitHub

    Directory of Open Access Journals (Sweden)

    Andrew E. Slaughter

    2015-11-01

    Full Text Available For the past several years, Idaho National Laboratory’s MOOSE framework team has employed modern software engineering techniques (continuous integration, joint application/framework source code repos- itories, automated regression testing, etc. in developing closed-source multiphysics simulation software (Gaston et al., 'Journal of Open Research Software' vol. 2, article e10, 2014. In March 2014, the MOOSE framework was released under an open source license on GitHub, significantly expanding and diversifying the pool of current active and potential future contributors on the project. Despite this recent growth, the same philosophy of concurrent framework and application development continues to guide the project’s development roadmap. Several specific practices, including techniques for managing multiple repositories, conducting automated regression testing, and implementing a cascading build process are discussed in this short paper. Special attention is given to describing the manner in which these practices naturally synergize with the GitHub API and GitHub-specific features such as issue tracking, Pull Requests, and project forks.

  11. Les conseils des cliniciens canadiens en matière de commotion dans le sport sont-ils cohérents?

    Science.gov (United States)

    Carson, James D.; Rendely, Alexandra; Garel, Alisha; Meaney, Christopher; Stoller, Jacqueline; Kaicker, Jatin; Hayden, Leigh; Moineddin, Rahim; Frémont, Pierre

    2016-01-01

    Résumé Objectif Comparer les connaissances et l’utilisation des recommandations concernant la prise en charge de la commotion dans le sport (CDS) démontrées par les spécialistes de la médecine du sport et de l’exercice (SMSE) et les urgentologues afin d’évaluer la réussite du transfert des connaissances sur la CDS au Canada. Conception Un sondage à choix multiples envoyé par courriel et autoadministré par des SMSE et des urgentologues. La validité du contenu du sondage a fait l’objet d’une évaluation. Contexte Canada. Participants Le sondage a été complété entre mai et juillet 2012 par des SMSE qui ont réussi l’examen menant au diplôme de l’Académie canadienne de la médecine du sport et de l’exercice et des urgentologues qui n’avaient pas ce diplôme. Principaux paramètres à l’étude La connaissance et l’identification des sources d’information sur la prise en charge des commotions, l’utilisation des stratégies de diagnostic de la commotion et l’utilisation d’une terminologie courante et cohérente dans l’explication des stratégies de repos aux patients après une CDS. Résultats Le taux de réponse était de 28 % (305 sur 1085). Les taux de réponse par les SMSE et les urgentologues se situaient respectivement à 41 % (147 sur 360) et 22 % (158 sur 725). Parmi les répondants, 41 % des urgentologues et 3 % des SMSE n’étaient pas au courant de l’existence de déclarations consensuelles sur la commotion dans le sport; 74 % des SMSE utilisaient « habituellement ou toujours » la version 2 de l’Outil d’évaluation de la commotion dans le sport (SCAT2), tandis que 88 % des urgentologues n’utilisaient jamais le SCAT2. Aucune réponse uniforme n’a été documentée à la question visant à connaître les meilleurs modes de repos cognitif. Conclusion Nous avons cerné des différences et un manque d’uniformité chez les SMSE et les urgentologues dans la mise en application des recommandations

  12. Endocrine control of active sodium transport across frog skin; Le controle endocrinien du transport actif de sodium a travers la peau de grenouille

    Energy Technology Data Exchange (ETDEWEB)

    Maetz, J. [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1959-07-01

    I. Action of the neurohypophyseal peptides on sodium transport. 1) On Rana Esculenta, oxytocin alone is active on the sodium transport (not vaso pressin). 2) The post hypophysis of R.e. contains an hormonal factor even more specific on Na transport (12 times more active than oxytocin). 3) This new factor must be closely related to oxytocin. II. Action of the adrenal corticoids. 1) The skin of frogs adapted to a salt-rich external medium, shows a considerable diminution in sodium uptake. 2) This decreased sodium uptake is brought back to normal by the injections of aldosterone. 3) This suggests that salt loading of amphibians (as well as mammals) inhibits the mineralocorticoid activity of the adrenals. (author) [French] I. Action des peptides neurohypophysaires chez Rana esculenta. 1) Le transport actif de Na est sensible a l'action de l'ocytocine mais non a l'hormone antidiuretique. 2) La posthypophyse de ces grenouilles contient un facteur plus specifique encore, puisque 12 fois plus actif que l'ocytocine. 3) Ce facteur est cependant tres voisin de l'ocytocine au point de vue chimique. lI. Action des corticoides surrenaliens chez Rana Esculenta. 1) L'adaptation des grenouilles a un milieu riche en sel a pour effet une diminution considerable du transport actif de sodium, visible in vivo et in vitro. 2) L'injection d'aldosterone a des grenouilles adaptees dans ces conditions restaure le transport actif a un niveau comparable a celui que l'on observe chez les animaux conserves dans de l'eau courante. 3) Ces faits suggerent que la surcharge en NaCI produirait chez les amphibiens, comme chez les mammiferes, une mise au repos de la fonction mineralotrope de la surrenale. (auteur)

  13. Investments of Banks in Securities: the Essence and Development Trends under Current Conditions

    Directory of Open Access Journals (Sweden)

    Ekaterina Vladimirovna Mazikova

    2015-12-01

    Full Text Available The implementation of modern banking activities involves the realization of investments. Investment is a complex discussion economic category, characterized by a number of features. The types and forms of investment are manifold and can be transformed with account of the state of the economy and the level of development of industrial relations. The faster growth of the financial sector in the economy has stipulated the development of financial investment. Banks as financial and lending institutions actively make financial investments in securities. Banks’ investment in securities pursues a number of purposes which determine the selection of securities for investment and their quality. The article identified the targets of bank investments in securities and their development trends under current conditions on the basis of the analysis of the actual data for 2010–2014. Negative revaluation and the actual decrease in the value of corporate securities of Russian issuers reduce their commercial appeal. Banks refuse to speculate on the stock market in favor of the securities that ensure liquidity. Banks’ investments aim to purchasing securities from the Lombard List of the Bank of Russia in order to obtain loans and participate in the repo transactions. Thus, during the analyzed period, banks’ investments in securities transformed from systemically important assets that generate substantial profit into the mechanism that provides liquidity. It should be noted that a significant part of investment resources of Russian banks services the debt obligations of Russia’s Government. The article also identified a trend of banks’ increasing investment in the participation portfolios of subsidiaries and associated joint stock companies. The official data of the Central Bank of the Russian Federation (Bank of Russia [15], and the Federal State Statistics Service [14] were used as the information base for the study

  14. On Variations in the Level of PER in Glial Clocks of Drosophila Optic Lobe and Its Negative Regulation by PDF Signaling.

    Science.gov (United States)

    Górska-Andrzejak, Jolanta; Chwastek, Elżbieta M; Walkowicz, Lucyna; Witek, Kacper

    2018-01-01

    We show that the level of the core protein of the circadian clock Period (PER) expressed by glial peripheral oscillators depends on their location in the Drosophila optic lobe. It appears to be controlled by the ventral lateral neurons (LNvs) that release the circadian neurotransmitter Pigment Dispersing Factor (PDF). We demonstrate that glial cells of the distal medulla neuropil (dMnGl) that lie in the vicinity of the PDF-releasing terminals of the LNvs possess receptors for PDF (PDFRs) and express PER at significantly higher level than other types of glia. Surprisingly, the amplitude of PER molecular oscillations in dMnGl is increased twofold in PDF-free environment, that is in Pdf 0 mutants. The Pdf 0 mutants also reveal an increased level of glia-specific protein REPO in dMnGl. The photoreceptors of the compound eye (R-cells) of the PDF-null flies, on the other hand, exhibit de-synchrony of PER molecular oscillations, which manifests itself as increased variability of PER-specific immunofluorescence among the R-cells. Moreover, the daily pattern of expression of the presynaptic protein Bruchpilot (BRP) in the lamina terminals of the R-cells is changed in Pdf 0 mutant. Considering that PDFRs are also expressed by the marginal glia of the lamina that surround the R-cell terminals, the LNv pacemakers appear to be the likely modulators of molecular cycling in the peripheral clocks of both the glial cells and the photoreceptors of the compound eye. Consequently, some form of PDF-based coupling of the glial clocks and the photoreceptors of the eye with the central LNv pacemakers must be operational.

  15. Collective Mind: Towards Practical and Collaborative Auto-Tuning

    Directory of Open Access Journals (Sweden)

    Grigori Fursin

    2014-01-01

    Full Text Available Empirical auto-tuning and machine learning techniques have been showing high potential to improve execution time, power consumption, code size, reliability and other important metrics of various applications for more than two decades. However, they are still far from widespread production use due to lack of native support for auto-tuning in an ever changing and complex software and hardware stack, large and multi-dimensional optimization spaces, excessively long exploration times, and lack of unified mechanisms for preserving and sharing of optimization knowledge and research material. We present a possible collaborative approach to solve above problems using Collective Mind knowledge management system. In contrast with previous cTuning framework, this modular infrastructure allows to preserve and share through the Internet the whole auto-tuning setups with all related artifacts and their software and hardware dependencies besides just performance data. It also allows to gradually structure, systematize and describe all available research material including tools, benchmarks, data sets, search strategies and machine learning models. Researchers can take advantage of shared components and data with extensible meta-description to quickly and collaboratively validate and improve existing auto-tuning and benchmarking techniques or prototype new ones. The community can now gradually learn and improve complex behavior of all existing computer systems while exposing behavior anomalies or model mispredictions to an interdisciplinary community in a reproducible way for further analysis. We present several practical, collaborative and model-driven auto-tuning scenarios. We also decided to release all material at c-mind.org/repo to set up an example for a collaborative and reproducible research as well as our new publication model in computer engineering where experimental results are continuously shared and validated by the community.

  16. Activités physiques libres ou encadrées et condition physique liée à la santé chez des adultes burundais: étude transversale

    Science.gov (United States)

    Bizimana, Jean Berchmans; Lawani, Mansourou Mohamed; Akplogan, Barnabé; Gaturagi, Charles

    2016-01-01

    Introduction l’activité physique régulière a un impact positif sur la santé. Cette étude a pour objet de comparer la condition physique liée à la santé des adultes qui s’exercent librement avec celle des adultes bénéficiant d’un encadrement professionnel. Elle tente aussi d’établir une relation entre le niveau d’activité physique et les paramètres de la condition liée à la santé. Méthodes nous avons évalué le niveau d’activité physique et les paramètres de la condition physique liée à la santé. Par le test t pour échantillons indépendants, nous avons comparé les moyennes et avons par le calcul du coefficient de corrélation r de Pearson analysé la relation entre le niveau d’activité physique et les paramètres de la condition physique. Résultats des écarts significatifs (p Le niveau d’activité physique est positivement corrélé (p le cholestérol HDL. Conclusion les résultats de cette étude montrent que l’activité physique libre est aussi efficace que l’activité physique encadrée dans le maintien des profils lipidique et physiologique favorables à la santé chez l’adulte burundais. Cependant, l’activité physique encadrée apporte des bénéfices supplémentaires pour le V˙O2max, la fréquence cardiaque de repos, la souplesse antérieure et la détente verticale PMID:28203315

  17. Long QT in children with congenital deafness: a brief report

    Directory of Open Access Journals (Sweden)

    Naseraldin Akbari Asbagh

    2013-08-01

    Full Text Available Background: Long QT syndromes (LQT are genetic abnormalities of ventricular repo-larization, with an estimated incidence of about one per 10000 births. It is characterized by prolongation of the QT interval in electrocardiogram (EKG and associated with a high risk for syncope and sudden death in patients. Type of this syndrome is association with congenital deafness. Our objective was to evaluate QT interval in children with congenital deafness.Methods: For 219 patients referred to Imam Khomeini Hospital audiometric clinic in 2011, questionnaire were completed. A total of 23 congenitally deaf children were incl-uded. All patients’ examinations were done by a pediatric cardiologist. Electrocardio-gram is conducted in all children (23 patients with sever and deep congenital deafness. Then the QT interval was measured based on Bazett’s formula. Echocardiography was also performed in these children to assess left ventricular function and the presence of mitral valve prolapse.Results: The overall patients were two hundred and nineteen children. A total of twenty three congenitally deaf children were included and electrocardiogram was obtained. Three children had obviously prolonged QTc (0.48±0.02 second. The median age of them was 6.1±5 year, the median weight was 18±11.3 kilogram and the median of QT interval was 0.48±0.02 second.Conclusion: The QT interval obtained 0.48±0.02 second. In the present study we found prolonged QT in congenital deafness, thus we recommend to evaluate the electrocardio-gram of children with congenital deafness.

  18. Endocrine control of active sodium transport across frog skin; Le controle endocrinien du transport actif de sodium a travers la peau de grenouille

    Energy Technology Data Exchange (ETDEWEB)

    Maetz, J [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1959-07-01

    I. Action of the neurohypophyseal peptides on sodium transport. 1) On Rana Esculenta, oxytocin alone is active on the sodium transport (not vaso pressin). 2) The post hypophysis of R.e. contains an hormonal factor even more specific on Na transport (12 times more active than oxytocin). 3) This new factor must be closely related to oxytocin. II. Action of the adrenal corticoids. 1) The skin of frogs adapted to a salt-rich external medium, shows a considerable diminution in sodium uptake. 2) This decreased sodium uptake is brought back to normal by the injections of aldosterone. 3) This suggests that salt loading of amphibians (as well as mammals) inhibits the mineralocorticoid activity of the adrenals. (author) [French] I. Action des peptides neurohypophysaires chez Rana esculenta. 1) Le transport actif de Na est sensible a l'action de l'ocytocine mais non a l'hormone antidiuretique. 2) La posthypophyse de ces grenouilles contient un facteur plus specifique encore, puisque 12 fois plus actif que l'ocytocine. 3) Ce facteur est cependant tres voisin de l'ocytocine au point de vue chimique. lI. Action des corticoides surrenaliens chez Rana Esculenta. 1) L'adaptation des grenouilles a un milieu riche en sel a pour effet une diminution considerable du transport actif de sodium, visible in vivo et in vitro. 2) L'injection d'aldosterone a des grenouilles adaptees dans ces conditions restaure le transport actif a un niveau comparable a celui que l'on observe chez les animaux conserves dans de l'eau courante. 3) Ces faits suggerent que la surcharge en NaCI produirait chez les amphibiens, comme chez les mammiferes, une mise au repos de la fonction mineralotrope de la surrenale. (auteur)

  19. In Vitro Comparison of Self-Expanding Versus Balloon-Expandable Stents in a Human Ex Vivo Model

    International Nuclear Information System (INIS)

    Grenacher, Lars; Rohde, Stefan; Gaenger, Ellen; Deutsch, Jochen; Kauffmann, Guenter W.; Richter, Goetz M.

    2006-01-01

    The objective was to compare the radial strength and expansile precision of self-expanding stents and balloon-expandable stents in a human cadaver bifurcation model. Seven different self-expanding (LUMINEXX, JOSTENT SelfX, JOSTENT SelfX hrf, Sinus-Repo, Sinus SuperFlex, Easy Wallstent, SMART) and four different balloon-expandable stent models (Palmaz, Sinus Stent, SAXX Medium, JOSTENT peripheral), each type 10 stents (total n = 110 stents) were implanted into the common iliac arteries of human cadaver corpses. The maximum stent diameter was 10 mm for all models. After stent implantation, the specimens were filled with silicone caoutchouc. After 24 h, the vascular walls including the stents were removed from the hardened casts. Diameters were taken and the weight of the cast cylinders was measured in air and in purified water to calculate the volume of the bodies (according to Archimedes Law) as a relative but precise degree for the radial strength of the implanted stents. The cylindrical casts of the self-expanding stents showed lower mean diameters (8.2 ± 1.0 mm) and mean volumes (0.60 ± 0.14 ml/cm) than in the balloon-expandable stent group (10.1 ± 0.3 mm and 0.71 ± 0.04 ml/cm, respectively; p < 0.01). The nominal maximum diameter of 10 mm was not achieved in any of the self-expanding stents, but this was achieved in more than 70% (29/40) of the balloon-expandable stent specimens (p < 0.05). The variation between achieved volumes was significantly larger in self-expanding (range: 0.23-0.78 ml/cm) than in balloon-expandable stents (range: 0.66-0.81 ml/cm; p < 0.05). Self-expanding stents presented considerably lower radial expansion force and lower degree of precision than balloon-expandable stents

  20. El control de los agregados monetarios: lecciones y experiencias del caso venezolano reciente The control of monetary aggregates: lessons and experiences from the recent Venezuelan case

    Directory of Open Access Journals (Sweden)

    Leonardo V. Vera

    2009-04-01

    Full Text Available Este trabajo intenta exponer las dificultades que confronta la autoridad monetaria para ejercer algún grado de control sobre los agregados monetarios, y para ello evalúa la experiencia reciente de una economía abierta y dependiente de un recurso mineral exportable como Venezuela. El trabajo no sólo expone argumentos analíticos, sino además provee evidencia muy sencilla en demostración de que existen numerosas fuentes de endogeneidad de la base monetaria, del multiplicador y de otros agregados más amplios en la economía venezolana. Aunque el Banco Central en Venezuela no viene anunciando ni explicando públicamente la estrategia y el alcance de la política monetaria, el trabajo muestra que la autoridad monetaria se ha movido sigilosamente, en los últimos tiempos, hacia una estrategia de uso de las tasas marcadores de las operaciones de mercado abierto como variable operativa buscando un objetivo final de actividad económica.This work examines the difficulties and formidable challenges faced by monetary authorities to control the behavior of monetary aggregates in an open economy dependent of an exportable natural resource such as Venezuela. The work not only introduces analytical arguments but also provides some empirical evidence that shows the several sources of endogeneity in the monetary base, the multiplier and other wider monetary aggregates in Venezuela. Though the Central Bank currently does not announce a clear strategy and target for the practice of monetary policy, we argue that the monetary authority has recently moved towards a strategy of targeting short-term interest rates. Presumably, the use of the repo rate as a monetary policy instrument is tied to a final target of economic activity.

  1. Congés… pour « prières » Prayers and days off

    Directory of Open Access Journals (Sweden)

    Claudine Viard

    2009-04-01

    Full Text Available Les premiers combats de la classe ouvrière se sont portés sur la demande d’une journée de repos, qui par tradition chrétienne a été fixée le dimanche en 1906. Quatre journées de congé à caractère chrétien ont en outre été retenues par le législateur. L’exercice du culte est donc concrètement garanti pour les chrétiens. Avec l’arrivée sur le territoire de la République  de populations de confessions variées, cette organisation du travail apparaît inégalitaire, voire de nature à porter atteinte à la liberté religieuse. Il a été proposé de reconnaître les jours de prières d’autres confessions. Pour l’instant, le législateur n’a pas adopté ces propositions. Mais la question reste posée. Or, la jurisprudence des tribunaux judiciaires et administratifs admet le droit de prier des fidèles des cultes minoritaires, ils peuvent prétendre à un congé lors des fêtes de leur religion dans la mesure où cela n’occasionne pas de perturbation. La consécration de cette jurisprudence souple par le législateur serait de nature à calmer le débat.At the turn of the century, the working classes fought for a day off in the week, which was granted on Sundays by the legislator in 1906. Four additional christian holidays are also legal. So the right to pray is garanteed for christians. As different populations with various faiths settled in France, this organisation has seemed to violate the principle of equality, and religious freedom. There has been a debate on the question whether some of the days of minority religions should also be observed by all the population. But so far, the legislator has not voted any of these proposals. It remains an issue. The French judge has consistently decided that the people of non christian faiths had the right to be granted a day off to pray on these special days, provided it would not cause prejudice to the organisation they work for. It might help to calm the debate if this

  2. Building Scientific Data's list of recommended data repositories

    Science.gov (United States)

    Hufton, A. L.; Khodiyar, V.; Hrynaszkiewicz, I.

    2016-12-01

    When Scientific Data launched in 2014 we provided our authors with a list of recommended data repositories to help them identify data hosting options that were likely to meet the journal's requirements. This list has grown in size and scope, and is now a central resource for authors across the Nature-titled journals. It has also been used in the development of data deposition policies and recommended repository lists across Springer Nature and at other publishers. Each new addition to the list is assessed according to a series of criteria that emphasize the stability of the resource, its commitment to principles of open science and its implementation of relevant community standards and reporting guidelines. A preference is expressed for repositories that issue digital object identifiers (DOIs) through the DataCite system and that share data under the Creative Commons CC0 waiver. Scientific Data currently lists fourteen repositories that focus on specific areas within the Earth and environmental sciences, as well as the broad scope repositories, Dryad and figshare. Readers can browse and filter datasets published at the journal by the host repository using ISA-explorer, a demo tool built by the ISA-tools team at Oxford University1. We believe that well-maintained lists like this one help publishers build a network of trust with community data repositories and provide an important complement to more comprehensive data repository indices and more formal certification efforts. In parallel, Scientific Data has also improved its policies to better support submissions from authors using institutional and project-specific repositories, without requiring each to apply for listing individually. Online resources Journal homepage: http://www.nature.com/scientificdata Data repository criteria: http://www.nature.com/sdata/policies/data-policies#repo-criteria Recommended data repositories: http://www.nature.com/sdata/policies/repositories Archived copies of the list: https

  3. The use of tracers in the study of the ionic permeability of the nerve; Utilisation des indicateurs nucleaires dans l'etude de la permeabilite ionique du nerf

    Energy Technology Data Exchange (ETDEWEB)

    Guinnebault, M [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1961-07-01

    The use of the radioactive tracers {sup 24}Na and {sup 42}K, and the electrophysiological fine study carried out on the plant Cephalopods nervous cells have made it possible, during ten years, to study the relationships between the electrical phenomena observed during the propagation of the nervous impulse and the ionic movements which occur at the cell membrane between the intra- and extra-cellular media. In the state of rest, the nerve fibres present a certain permeability towards sodium and potassium, a permeability which allows the renewal, from the extra-cellular medium, of the cations contained in the cytoplasm. At the moment of the passage of the nervous impulse, it is possible to demonstrate a temporary increase in the permeability towards the sodium which causes the entry of Na{sup +} ions into the nerve fibre, whilst, a few milliseconds later, the increase in the potassium permeability causes the departure of an equivalent quantity of K{sup +} ions. A recovery phase follows the passage of the nervous impulse, during which the original ionic conditions are re-established. If the potassium movements can be considered as passive, the expulsion of Na{sup +} requires, on the part of the cell, the use of a part of the metabolic energy. (author) [French] L'utilisation des indicateurs radioactifs {sup 24}Na et {sup 42}K, et l'etude electrophysiologique fine realisee sur des cellules nerveuses geantes de Cephalopodes a permis, depuis une dizaine d'annees, d'etudier les rapports entre les phenomenes electriques observes lors de la propagation de l'influx nerveux et les mouvements ioniques qui s'effectuent au niveau de la membrane cellulaire entre milieux intracellulaire et extracellulaire. A l'etat de repos, les fibres nerveuses possedent pour le sodium et le potassium, une permeabilite qui permet le renouvellement, a partir du milieu extracellulaire des cations contenus dans le cytoplasme. Au moment du passage de l'influx nerveux, on peut mettre en evidence une

  4. Le cancer différencié de la thyroïde chez l’enfant et l’adolescent: à propos de 22 cas

    Science.gov (United States)

    Anajar, Said; Tatari, Mohammed; Lakhbal, Adil; Abada, Reda; Rouadi, Sami; Roubal, Mohammed; Mahtar, Mohammed

    2017-01-01

    L’obectif était de mettre en relief les particularités du cancer de la thyroïde chez l’enfant et l’adolescent, et d’évaluer nos résultats par rapport à la littérature internationale a travers une série de cas la plus représentatif au Maroc: 22 cas. C'est une étude rétrospective descriptive des patients atteints de cancer différencié de la thyroïde, hospitalisés au service d’ORL et de Chirurgie Cervico-faciale de L’hopital 20 Août de Casablanca-Maroc, sur la période qui s’étend de Janvier 1995 à Mars 2015. Nous avons recueilli les données relatives à 22 cas, qui répondaient à nos critères d’inclusion. L’âge moyen de nos patients était de 14 ans, avec une sex-ratio 3,4, la plupart de nos patients ont consulté pour un nodule thyroïdien, associé dans 22,7% des cas à une adénopathie cervicale, et dans 9,1% à des signes de compression. L’ensemble des patients ont bénéficié d’une thyroïdectomie totale, suivie d’un curage ganglionnaire dans 31,82%. Le diagnostic de cancer thyroïdien a reposé sur l’examen anatomopathologique de la pièce opératoire, qui a objectivé un carcinome papillaire dans 95,4% des cas, et un carcinome vésiculaire dans 4,5%. Le traitement par l’iode radioactif 131 a été réalisé dans 100% des cas. Par la suite tous nos patients ont été mis sous hormonothérapie thyroïdienne. Une surveillance étroite et régulière a permis de détecter des métastases ganglionnaires chez 3 patients, et les métastases à distance chez 4 patients. Le cancer différencié de la thyroïde de l’enfant et l’adolescent est une entité rare mais agressive, son traitement se base sur la chirurgie, associée à l’irathérapie donnant un pronostic excellent. PMID:29255541

  5. Effects of Aging Quartz Sand and Hanford Site Sediment with Sodium Hydroxide on Radionuclide Sorption Coefficients and Sediment Physical and Hydrologic Properties: Final Report for Subtask 2a

    Energy Technology Data Exchange (ETDEWEB)

    DI Kaplan; JC Ritter; KE Parker

    1998-12-04

    in the various treatment solutions. It is clear from these experiments that the background chemistry of the waste-glass Ieachate is likely to have a significant effect on the hydrology and radionuclide geochemistry in the near-field environment of the ILAW.' These experiments provided an important f~st approximation of several chemical and physical processes. Future research, together with the data presented in this repo~ will provide important guidance for the selection of near-field hydraulic and geochemical input data for the ILAW-PA.

  6. Le recours aux archives judiciaires pour étudier les habitudes de sommeil

    Directory of Open Access Journals (Sweden)

    Guillaume Garnier

    2009-10-01

    Full Text Available Les archives judiciaires possèdent de nombreux attraits, et certains sont parfois insoupçonnés. Les faits relatés dans les actes d’accusation par exemple, mais aussi les déclarations de témoins recèlent de petits détails sur les habitudes de sommeil qui passent souvent inaperçus aux yeux des historiens. Dans un corpus très large (du XVIIIe au xixe siècle on peut ainsi tenter de comprendre les logiques de sommeil : heures de coucher et lever, durée du sommeil, l’apparente vulnérabilité du repos nocturne, les déviances nocturnes, le lieu de sommeil. Mais dans une vue plus globale, les archives aident aussi à déterminer les rythmes nocturnes et notamment la place qu’y tient le sommeil. Les contraintes sociales et politiques, la dureté du travail et de la vie, l’importance de la religion transparaissent aussi pour former une culture spécifique du sommeil préindustriel.Judiciary records have many appealing aspects, some of which one would not suspect. What is related in indictment documents for instance, as well as in evidence statements, contains small details about sleeping habits that often go unnoticed by historians. Out of a very large corpus (from the xviiith till the xixth century, one can try and work out the rationale behind sleep: at what time people go to sleep or wake up, for how long, how vulnerable night sleep seems to be, nocturnal deviances, or where people sleep. But to a larger extent, records also help to determine nocturnal rhythms and more specifically the place that sleep holds in them. Social and political constraints, harshness of working and living conditions, the importance of religion, all show through and convey a specific culture of pre-industrial sleep.

  7. Monazite-type ceramics for conditioning of minor actinides. Structural characterization and properties

    International Nuclear Information System (INIS)

    Babelot, Carole

    2013-01-01

    The minor actinides (MA) neptunium, americium, and curium are mainly responsible for the long-term radiotoxicity of the High Active Waste (HAW) generated during the nuclear power operation. If these long-lived radionuclides are removed from the HAW by partitioning and converted by neutron fission (transmutation) into shorter-lived or stable elements, the remaining waste loses most of its long-term radiotoxicity. Thus, partitioning and transmutation (P and T) are considered as attractive options for reducing the burden on geological disposals. As an alternative, these separated MA can also be conditioned (P and C strategy) in specifically adapted ceramics to ensure their safe final disposal over long periods. At the moment, spent fuel elements are foreseen either for direct disposal in deep geological repositories or for reprocessing. The highly active liquid waste that is produced during reprocessing is conditioned industrially using a vitrification process before final disposal. Although the widely used borosilicate glasses meet most of the specifications needed, ceramic host matrices appear to be even more suitable in terms of resistance to corrosion. The development of new materials based on tailor-made highly specific ceramics with extremely stable behavior would make it possible to improve the final storage of long-lived high-level radiotoxic waste. In the framework of this PhD research project, monazite-type ceramics were chosen as promising host matrices for the conditioning of trivalent actinides. The focus on the monazite-type ceramics is justified by their properties such as high chemical durability. REPO 4 ceramics are named monazite for RE = La - Gd (monoclinic symmetry) and xenotime for RE = Tb - Lu and Y (tetragonal symmetry). The objective of this study is to contribute to the understanding of the alteration behavior of such ceramics under the repository conditions. REPO 4 (with RE = La, Eu) is prepared by hydrothermal synthesis at 200 C. Structural

  8. The Use of Copper- 64 in the Investigation of Reaction Mechanisms of Enzymes, Particularly as Related to Food Processing; Emploi de Cuivre-64 dans l'Etude des Mecanismes de Reaction des Enzymes, Notamment en Ce Qui Concerne la Preparation des Denrees Alimentaires; ПРИМЕНЕНИЕ МЕДИ-64 ДЛЯ ИССЛЕДОВАНИЯ МЕХАНИЗМОВ ФЕРМЕНТАТИВНЫХ РЕАКЦИЙ, СВЯЗАННЫХ С ОБРАБОТКОЙ ПИЛИ; Empleo de Cobre-64 en el Estudio de los Mecanismos de Reacciones Enzima Ticas de Interes para la Elaboracion de Alimentos

    Energy Technology Data Exchange (ETDEWEB)

    Arthur, Jr., J. C.; McLemore, T. A. [Southern Regional Research Laboratory, New Orleans, LA (United States)

    1963-03-15

    The oxidative enzymes of plant tissues are often dormant or only slightly active during the resting state, becoming active on the injury of the tissue or on separation from the tissue. During food processing this results in an acceleration of the oxidation of the natural substrates and polymerization of the products, which discolour the tissue. Copper oxidases are the principal enzymes involved in catalysing these reactions. The activation of the enzyme also leads to its reaction inactivation. One of the causes of the phenomenon of reaction inactivation is the decrease in the effective concentration of the enzyme, probably by the removal or binding of its metal prosthetic group copper. By using copper- 64, in vitro, it was shown that, in a resting solution, cupric ion can complex and/or exchange with the copper of the enzyme and that, in oxidizing solutions, an additional amount of cupric ion can be complexed. Cu-o-quinone- type complexes have higher formation constants than Cu-p-quinone- type complexes. The amount of cupric ion complexed was decreased, if the ion was added in an oxidizing solution after the initiation of polymerization of the o-quinone type reaction products. The kinetics of the exchange and complexing processes for cupric ions with enzyme and reaction products are discussed mathematically. (author) [French] Les enzymes oxydants des tissus vegetaux sont souvent inactifs ou tres peu actifs a l'etat de repos et ne deviennent actifs qu'en cas de lesion du tissu ou lorsqu'ils sont separes de celui-ci. Lors de la preparation des denrees alimentaires, ce phenomene a pour effet d'accelerer l'oxydation des substrats naturels et de polymeriser les produits, ce qui donne lieu a une decoloration du tissu. Les oxydases de cuivre sont les principaux enzymes qui interviennent comme catalyseurs dans ces reactions. L'activation de l'enzyme entraine en outre une inhibition de la reaction qu'il subit. Une des causes de ce phenomene est la diminution de la

  9. Monazite-type ceramics for conditioning of minor actinides. Structural characterization and properties

    Energy Technology Data Exchange (ETDEWEB)

    Babelot, Carole

    2013-07-01

    The minor actinides (MA) neptunium, americium, and curium are mainly responsible for the long-term radiotoxicity of the High Active Waste (HAW) generated during the nuclear power operation. If these long-lived radionuclides are removed from the HAW by partitioning and converted by neutron fission (transmutation) into shorter-lived or stable elements, the remaining waste loses most of its long-term radiotoxicity. Thus, partitioning and transmutation (P and T) are considered as attractive options for reducing the burden on geological disposals. As an alternative, these separated MA can also be conditioned (P and C strategy) in specifically adapted ceramics to ensure their safe final disposal over long periods. At the moment, spent fuel elements are foreseen either for direct disposal in deep geological repositories or for reprocessing. The highly active liquid waste that is produced during reprocessing is conditioned industrially using a vitrification process before final disposal. Although the widely used borosilicate glasses meet most of the specifications needed, ceramic host matrices appear to be even more suitable in terms of resistance to corrosion. The development of new materials based on tailor-made highly specific ceramics with extremely stable behavior would make it possible to improve the final storage of long-lived high-level radiotoxic waste. In the framework of this PhD research project, monazite-type ceramics were chosen as promising host matrices for the conditioning of trivalent actinides. The focus on the monazite-type ceramics is justified by their properties such as high chemical durability. REPO{sub 4} ceramics are named monazite for RE = La - Gd (monoclinic symmetry) and xenotime for RE = Tb - Lu and Y (tetragonal symmetry). The objective of this study is to contribute to the understanding of the alteration behavior of such ceramics under the repository conditions. REPO{sub 4} (with RE = La, Eu) is prepared by hydrothermal synthesis at 200 C

  10. Estudo dos factores limitativos do exercício físico em doentes com doença pulmonar obstrutiva crónica

    Directory of Open Access Journals (Sweden)

    Fátima Rodrigues

    2004-01-01

    exercise limitation factors in each patient.The identification of exercise limitation factors will certainly contribute to towards defining the best therapeutic approach in COPD patients.REV PORT PNEUMOL 2004; X (1: 9-61 RÉSUMÉ: La Bronchopneumopathie Chronique Obstructive (BPCO est une cause majeure de morbidité et de mortalité dans le monde. Les patients BPCO modérés à sévères montrent d’importantes limitations à l’exercice physique dans leurs activités journalières, affectant de manière significative leur qualité de vie. Il existe plusieurs causes à cette limitation identifiées dans la littérature: les limitations des débits ventilés, l’hyperinflation pulmonaire, la faiblesse des muscles respiratoires et périphériques, parmi d’autres.Le but de cette étude etait d’identifier les facteurs en relation possible avec la limitation de la performance physique chez un groupe de patients BPCO modérés à sévères.Nous avons étudié 24 sujets masculins, âgés de 64,13+8,46 ans (de 46-83 ans, FEV1:46,96+12,99%, FRC: 144,71+26,86%, DLCO: 69,88+16,49 % (% de la valeur prédite, PaO2:78,25+7,82 mmHg, PaCO2:40,78+4,28 mmHg. Les patients ont réalisé un exercice à charge croissante sur bicyclette ergométrique jusqu’à la limite imposée par les symptômes. Nous avons comparé les paramètres de la fonction pulmonaire au repos et à l’exercice avec la consommation maximale d’oxygène, le travail maximal supporté et le temps d´épreuve jusqu´à l´exhaustion.Les principaux facteurs limitant l’exercice physique sont les anomalies des échanges gazeux, la limitation ventilatoire et de faibles valeurs de l’index de masse corporelle.L’hyperinflation au repos n’est pas corrélée avec la performance physique. L’hyperinflation dynamique contribue de manière importante à l

  11. Sommeil et course au large en solitaire : comportements des coureurs et étude de faisabilité d’un « agenda interactif de sommeil » Sleep and solo sailing racing : behaviour of racers and feasibility study of an “interactive sleep diary” Sueño y regata a vela en solitario : comportamientos de los corredores y Estudio de factibilidad de una “agenda interactiva de sueño”

    Directory of Open Access Journals (Sweden)

    Denis Theunynck

    2010-05-01

    Full Text Available La course au large en solitaire associe un effort physique et cognitif intense et prolongé durant 10 à 100 jours dans des conditions extrêmes. Elle implique le recours à un sommeil fractionné et des périodes de repos courtes réparties sur l’ensemble du nycthémère. Ces difficultés sont évoquées pour expliquer les incidents, accidents et altérations des performances.Cette étude recense les stratégies mises en œuvre par neuf des meilleurs skippers de la spécialité pour préparer puis gérer ces contraintes au cours d’une course, puis suit un skipper durant une course autour du monde en solitaire et sans escale d’une durée de cent jours.A partir de ces observations, il a été proposé à un skipper expérimenté de tester un agenda interactif de « sommeil » afin d’apprendre à gérer de façon optimale ses périodes de repos durant une course.Ce travail met en évidence que les sujets sont conscients de l’importance de gérer leurs périodes de repos, mais mettent en œuvre peu de stratégies de préparation et de gestion du sommeil avant et durant leur course. Ils présentent une période d’adaptation à ces conditions extrêmes allant de 24 à 72 heures et rencontrent ensuite des périodes de fatigue extrême avec hallucinations. Cette fatigue a des conséquences sur la performance, mais aussi sur l’accidentologie qui apparaît nettement majorée avec un possible délai allant jusqu’à 72h après l’installation d’une dette de sommeil trop importante. Les outils de laboratoire, qui ne pourraient donner des informations intéressantes que sur la base d’une utilisation continue, sont très difficiles à mettre en œuvre ici.Dans ces circonstances, le recours à un agenda de sommeil « interactif », utilisé par le sujet pour comptabiliser et gérer la répartition et la durée de ses périodes de sommeil, semble être une solution individuelle de gestion des alternances veille sommeil. Il pourrait

  12. Caractérisation rhéologique et modélisation structurelle des systèmes argile-polymère. Application aux fluides de forage Rheometry and Structural Modelling of Clay-Polymer Systems. Application to Drilling Fluids

    Directory of Open Access Journals (Sweden)

    Cartalos U.

    2006-12-01

    Full Text Available Le comportement rhéologique des systèmes argile-polymère couramment utilisés dans les formulations des fluides de forage est examiné dans cet article. Un protocole d'essai adapté à leur nature thixotrope qui permet d'effectuer des mesures reproductibles est mis au point. Les propriétés intrinsèques du matériau sont ainsi déterminées sur toute la gamme de sollicitations : du comportement solide aux faibles déformations au comportement fluide aux taux de déformations intenses. Il est montré que ces systèmes sont caractérisés par des temps de restructuration longs, par des rhéogrammes en régime permanent présentant un minimum de contrainte et par des dépassements importants de la contrainte lors des essais transitoires. Ces effets peuvent être complètement masqués par des procédures d'essai préconisés par les normes en vigueur dans le forage. Une loi de comportement structurelle récente qui relie les propriétés thixotropes et viscoélastiques du matériau aux mécanismes de création et de rupture des flocs peut reproduire l'ensemble des phénomènes observés. Sa capacité de décrire le changement de structure au sein du fluide sous écoulement ou au repos et les variations associées de la contrainte permet d'envisager une meilleure modélisation de l'hydraulique du forage. The rheological behaviour of clay-polymer systems that are currently used in the formulation of drilling fluids was studied. A specific experimental procedure was used to account for thixotropic effects and obtain, thus, reproducible results. In this way it was possible to determine intrinsic properties in the whole range, from solid behaviour below the yield stress to liquid behaviour at very high shear. These systems are shown to be characterised by very long time scales of structure recovery, by the existence of a minimum shear stress in the steady state flow curve and by important stress overshoots in transient flows. These effects can be

  13. Étude des distributions de contraintes autour d'un puits pétrolier. Application au calcul des pressions d'initiation de fracturation hydraulique Research on Stress Distribution Around an Oil Or Gas Well. Application to Calculating Pressures for Initiating Hydraulic Fracturing

    Directory of Open Access Journals (Sweden)

    Skoczylas F.

    2006-11-01

    Full Text Available Des méthodes de résolution analytiques et numériques ont été proposées, pour déterminer les distributions de contraintes autour de forages pétroliers dans le cas de matériaux peu résistants. Le calcul de ces distributions aboutit à la détermination des pressions de fracturation. Le critère de plasticité de Mohr-Coulomb a été choisi pour la résolution analytique. Cette étude permet d'établir trois schémas types de distribution de contraintes, au moment de la fracturation, pour un régime permanent d'écoulement. La géométrie axisymétrique du modèle a permis d'utiliser une méthode numérique par schéma aux différences finies. La loi de comportement du matériau est déduite du critère de plasticité de Drucker. Cette résolution permet le chargement incrémental en pression dans le forage et de simuler une injection rapide par un couplage simplifié fluide-squelette. Le modèle élastoplastique à deux surfaces de charge de Lade-Shao a finalement été retenu pour décrire l'écrouissage du matériau. La comparaison des résultats des différentes méthodes de calcul s'effectue sur la base de l'influence respective du coefficient de poussée au repos Ko, du coefficient de Poisson et de la résistance à la compression, Co, du matériau. Analytical and numerical methods are proposed, in order to determine stresses distribution around borehole for axisymetric problems in the case of low strengh materials. Calculation of these distributions leads to the determination of hydraulic fracture-pressure. Analytical solutions were found in the case of Mohr-Coulomb criterion and steady flow. These solutions leads to three typical stresses distributions when hydraulic fracture takes place. Because problem's axisymetry, the finite difference method was used. The constitutive law was deduced using Drücker plasticity criterion with an associated flow rule for elastic perfectly plastic behaviour. Such a numerical method can take into

  14. Sharing environmental models: An Approach using GitHub repositories and Web Processing Services

    Science.gov (United States)

    Stasch, Christoph; Nuest, Daniel; Pross, Benjamin

    2016-04-01

    accordingly. The admin tool of the 52°North WPS was extended to support automated retrieval and deployment of computational models from GitHub repositories. Once the R code is available in the GitHub repo, the contained process can be easily deployed and executed by simply defining the GitHub repository URL in the WPS admin tool. We illustrate the usage of the approach by sharing and running a model for land use system archetypes developed by the Helmholtz Centre for Environmental Research (UFZ, see Vaclavik et al.). The original R code was extended and published in the 52°North WPS using both, public and non-public datasets (Nüst et al., see also https://github.com/52North/glues-wps). Hosting the analysis in a Git repository now allows WPS administrators, client developers, and modelers to easily work together on new versions or completely new web processes using the powerful GitHub collaboration platform. References: Hinz, M. et. al. (2013): Spatial Statistics on the Geospatial Web. In: The 16th AGILE International Conference on Geographic Information Science, Short Papers. http://www.agile-online.org/Conference_Paper/CDs/agile_2013/Short_Papers/SP_S3.1_Hinz.pdf Nüst, D. et. al.: (2015): Open and reproducible global land use classification. In: EGU General Assembly Conference Abstracts . Vol. 17. European Geophysical Union, 2015, p. 9125, http://meetingorganizer.copernicus. org/EGU2015/EGU2015- 9125.pdf Vaclavik, T., et. al. (2013): Mapping global land system archetypes. Global Environmental Change 23(6): 1637-1647. Online available: October 9, 2013, DOI: 10.1016/j.gloenvcha.2013.09.004

  15. « Mythologie de la raison »

    Directory of Open Access Journals (Sweden)

    Panagiotis Thanassas

    2005-04-01

    Full Text Available Le manuscrit de Hegel découvert en 1917 et connu comme « le plus ancien programme systématique de l'idéalisme allemand » est considéré comme un texte emblématique pour le processus de genèse de l’idéalisme allemand. Bien qu’il adopte la langue de Kant et la « révolution copernicienne » que ce dernier avait apportée en fondant la philosophie sur le sujet pensant, ce texte formule des questions qui avaient été laissées sans réponse par le kantisme, en demandant qu’elles soient reposées dans le cadre d’un nouveau fondement, systématique, de la philosophie. Le système que trace Hegel culmine avec l’idée suprême, l’idée du Beau, dans laquelle « la Vérité et la Bonté s’allient ». Le sens esthétique est érigé en « instrument » philosophique fondamental, indispensable à l’acte esthétique « suprême » par lequel la Raison conçoit et « englobe toutes les idées ». L’élément esthétique est également nécessaire à la nouvelle Volksreligion proclamée par le projet utopique hégélien. Enfin, en dépit des références kantiennes indubitables, l’ambition profonde du texte reste le dépassement d’un questionnement transcendantal orienté vers la conscience et son remplacement par un désir d’origine romantique de dépassement de toute dichotomie et d’atteindre l’union avec l’absolu.Hegel’s manuscript, which was found in 1917 and became known as “The earlier systematic programme of German idealism”, is considered to be a central text in the birth process of German Idealism. Although it adopts Kant’s language and the “Copernican shift” he introduced through the grounding of philosophy on the thinking subject, this extract raises questions that were left unanswered by Kantianism, with a view of re-positing them in the frame of a new systematic grounding of philosophy. The system sketched by Hegel culminates in the “highest idea” of the beautiful, in which

  16. La fatigue du patron pêcheur dans l’activité de chalutiers pélagiques : approche d’anthropologie cognitive The captain’s fatigue in the pelagic trawler activity: a cognitive anthropology approach La fatiga del capitan de pesca en la actividad de los pescadores pelágicos : un enfoque de antropologia cognitiva

    Directory of Open Access Journals (Sweden)

    Bastien Sennegon

    2011-05-01

    Full Text Available Nous avons analysé les processus de fatigue à travers l’activité de trois patrons pêcheurs de chalutiers pélagiques.Nous nous sommes focalisés sur la fatigue perçue d’un point de vue psychologique. Le recueil de données s’est effectué en situation naturelle. Notre méthode a combiné l’observation directe et des entretiens compréhensifs. Les rythmes de travail sont la principale cause de fatigue, car les périodes de repos n’autorisent pas une récupération suffisante. Ainsi, nous notons une accumulation de la fatigue d’ordre psychologique tout au long de la saison de pêche. Cette récupération est limitée par les troubles du sommeil observés à bord. De surcroît, l’analyse de l’activité du patron pêcheur révèle une charge de travail conséquente à la source de stress et de risque dans ce contexte de vigilance minorée.We analyzed the dynamics of the fatigue processes through the activity of pelagic trawlers captains.We focussed on perceived fatigue from a psychological point of view. The data were collected in natural situation. Our methodology combined direct observation with non-directive interviews.The work rhythms aboard trawlers (phases of work and rest alternation are the main cause of the captain’s fatigue. The short periods of rest do not authorize a sufficient recovery. Thus, we note a fatigue accumulation throughout the trawling season. In addition, the recovery is restricted by the sleep disorders observed during the embarkations. The analysis of the trawler captain’s activity reveals workload, causing stress, as well as risk-taking in a diminished vigilance context.Analizamos los procesos de fatiga a traves de la actividad de tres capitanes de pesca de los barcos pescadores pelágicos. Nos concentramos sobre la fatiga percibida desde el punto de vista psicológico. La colecta de datos se efectuó en situacion natural. Nuestro método combina la observación directa y entrevistas no dirigidas

  17. Le conflit fémoro-acétabulaire et la coxarthrose

    Science.gov (United States)

    Zhang, Charlie; Li, Linda; Forster, Bruce B.; Kopec, Jacek A.; Ratzlaff, Charles; Halai, Lalji; Cibere, Jolanda; Esdaile, John M.

    2015-01-01

    Objectif Expliquer la présentation clinique, les observations à l’examen physique, les critères diagnostiques et les options de prise en charge du conflit fémoroacétabulaire (CFA). Sources des données Une recherche documentaire a été effectuée dans PubMed pour trouver des articles pertinents sur la pathogenèse, le diagnostic, le traitement et le pronostic du CFA. Message principal Depuis les dernières années, on reconnaît de plus en plus que le CFA est un précurseur potentiel et une étiologie importante des douleurs à la hanche dans la population adulte et de la coxarthrose idiopathique plus tard dans la vie. Le conflit fémoro-acétabulaire désigne un ensemble d’anomalies morphologiques osseuses de l’articulation de la hanche qui se traduit par un contact anormal durant le mouvement. Le CFA par effet came concerne une proéminence osseuse non sphérique du col fémoral proximal ou de la jonction tête-col. Le CFM par effet tenaille désigne une couverture acétabulaire excessive par-dessus la tête du fémur, qui peut se produire en raison de diverses variantes morphologiques. Les patients qui ont un CFA présentent une douleur inguinale antérieure chronique, profonde ou lancinante, le plus souvent en position assise, durant ou après une activité. Les patients peuvent aussi ressentir des douleurs occasionnelles aiguës durant l’activité. Il faut procéder à une anamnèse approfondie portant notamment sur l’incidence de traumatismes ou la fréquence de l’exercice. Il faut aussi faire un examen physique complet des hanches, de la région lombaire et de l’abdomen pour évaluer d’autres causes de douleurs inguinales antérieures. Le diagnostic de CFA est confirmé par radiographie. Le conflit fémoro-acétabulaire peut être pris en charge selon une approche conservatrice comportant du repos, la modification des activités, des médicaments et de la physiothérapie ou encore être traité par intervention chirurgicale. Conclusion

  18. Agreement for depression diagnosis between DSM-IV-TR criteria, three validated scales, oncologist assessment, and psychiatric clinical interview in elderly patients with advanced ovarian cancer

    Directory of Open Access Journals (Sweden)

    Rhondali W

    2015-07-01

    Full Text Available Wadih Rhondali,1 Gilles Freyer,2 Virginie Adam,3 Marilène Filbet,4 Martine Derzelle,5 Gaelle Abgrall-Barbry,6 Sophie Bourcelot,7 Jean-Louis Machavoine,8 Muriel Chomat-Neyraud,9 Olivier Gisserot,10 Rémi Largillier,11 Annick Le Rol,12 Frank Priou,13 Pierre Saltel,14 Claire Falandry15 1Clinique Mon Repos, Clinea, Marseille, France; 2Medical Oncology Unit, Centre Hospitalier Lyon Sud, Université Lyon 1, Pierre-Benite, France; 3Institut de Cancérologie de Lorraine Alexis Vautrin, Vandoeuvre-lès-Nancy, France; 4Palliative Unit, Centre Hospitalier Lyon Sud, Université Lyon 1, Pierre-Benite, France; 5Institut Jean Godinot, Reims, France; 6Tenon Hospital, Assistance Publique Hôpitaux de Paris, Paris, France; 7Centre Léon Bérard, Lyon, France; 8Centre François Baclesse, Caen, France; 9Centre Hospitalier de la région d’Annecy, Pringy, France; 10Hôpital d’Instruction des Armées Sainte-Anne, Toulon, France; 11Centre Azuréen de Cancérologie, Mougins, France; 12Medical Oncology, Hôpital Perpétuel Secours, Levallois-Perret, France; 13Medical Oncology, Centre Hospitalier Départemental Les Oudairies, La Roche-sur-Yon, France; 14Supportive Care Department, Centre Léon Bérard, Lyon, France; 15Geriatrics and Oncology Unit, Centre Hospitalier Lyon Sud, Université Lyon 1, Pierre-Bénite, France Background: Depression, a major outcome in cancer patients, is often evaluated by physicians relying on their clinical impressions rather than patient self-report. Our aim was to assess agreement between patient self-reported depression, oncologist assessment (OA, and psychiatric clinical interview (PCI in elderly patients with advanced ovarian cancer (AOC.Methods: This analysis was a secondary endpoint of the Elderly Women AOC Trial 3 (EWOT3, designed to assess the impact of geriatric covariates, notably depression, on survival in patients older than 70 years of age. Depression was assessed using the Geriatric Depression Scale-30 (GDS, the Hospital

  19. L'effet Peltier appliqué à la conception et la réalisation d'un nouveau capteur de débit massique

    Science.gov (United States)

    Wattiau, F.; Gaviot, E.; Thery, P.

    1993-08-01

    éalisation d'un nouveau capteur de débit massique basé sur l'effet Peltier. Le capteur en forme de circuit imprimé bimétallique, comporte plusieurs pistes métalliques continues parallèles entre elles et partiellement recouvertes par un grand nombre de dépôts électrolytiques de nature différente. Un tel circuit se comporte comme un circuit thermoélectrique classique dans lequel les parties homogènes non recouvertes par le dépôt électrolytique constituent le premier conducteur du couple, les parties plaquées constituant le second conducteur. La méthode de mesure consiste à faire passer un courant électrique dans une ou plusieurs pistes constituant le circuit émetteur de façon à générer par effet Peltier des gradients thermiques qui seront détectés par un circuit détecteur identique placé à proximité. Dans le cas particulier d'un fluide au repos, la f.e.m. détectée par le circuit détecteur dépend de la conductivité thermique du fluide. Lorsque le fluide est en mouvement relatif par rapport au circuit, il est possible de détecter une f.e.m. dépendant en grandeur et en signe de la vitesse d'écoulement du fluide. A titre d'application un capteur de débit massique a été réalisé en plaçant les circuits thermoélectriques dans une canalisation parcourue par le fluide en mouvement.

  20. Studies on the Influence of Tritium Radiation on Anaerobic Bacteria from the Bovine Rumen; Influence de l'Irradiation par le Tritium sur les Bacteries Anaerobies du Rumen des Bovins; 0418 0441 0414 ; Estudios sobre los Efectos de las Radiaciones del Tritio en las Bacterias Anaerobias de la Panza de los Bovinos

    Energy Technology Data Exchange (ETDEWEB)

    Brueggemann, J.; Giesecke, D. [Institute of Physiology and Animal Nutrition, University of Munich, Munich, Federal Republic of Germany (Germany)

    1962-02-15

    flore au repos a 0 Degree-Sign C, la dose totale etant d'environ 300 krads en 20 jours; cependant, il est difficile de repeter l'experience dans des conditions identiques par suite de l'heterogeneite de la substance. D'autres experiences ont ete faites sur des cultures pures de souches choisies de bacteries du rumen. Des doses allant jusqu'a 150 krads en 5 jours n'ont eu aucune influence marquee sur la croissance anaerobie et le metabolisme des hydrates de carbones. Toutefois, en presence d'oxygene pendant l'irradiation de cellules au repos, on a note une forte reduction du nombre des bacteries viables. On a constate que l'oxygene exercait un effet letal sur ces especes, suivant un ordre de decroissance logarithmique. On suppose que l'action de T{sub 2}O sur ces microorganismes prives de catalase est surtout attribuable aux produits secondaires d'irradiation, notamment a H{sub 2}O{sub 2}. Cependant, il reste encore a obtenir quelques resultats qui corroboreraient cette hypothese. (author) [Spanish] La flora bacteriana presente en la panza de los bovinos se compone en su mayoria de especies estrictamente anaerobias que proveen al huesped de grandes cantidades de acidos grasos volatiles (AGV), como principal fuente de energia. Dicha flora se ha sometido a irradiaciones prolongadas in vitro, utilizando T{sub 2}O, en una ''panza artificial'', en condiciones anaerobias, y se ha observado que las dosis de hasta 75 krad no ejercen efecto inhibitorio alguno sobre la proliferacion de las bacterias ni sobre la produccion de AGV. Despues de irradiar la flora en reposo a 0 Degree-Sign C con una dosis total de unos 300 krad durante 20 dias, se observaron efectos estimulantes que se traducen en una aceleracion de la division celular y en un aumento de la cantidad de AGV, pero, dada la heterogeneidad del material empleado, resulta dificil repetir el experimento en igualdad de condiciones. Se han realizado otros ensayos con cultivos puros de cepas seleccionadas de bacterias de la panza

  1. The Cobalt-60 Research Facility at Seibersdorf; L'Installation de Recherche sur l'Iradiation au {sup 60}Co de Seibersdorf; Obluchayushchaya ustanovka s istochnikom Kobal'ta-60 reaktornogo tsentra v Zajbersdorfe; La Instalacion Experimental de {sup 60}Co de Seibersdorf

    Energy Technology Data Exchange (ETDEWEB)

    Weidinger, N.; Kaindl, K. [Institute Of Biology And Agriculture, Reactor Centre, Seibersdorf (Austria)

    1966-11-15

    shield to enable the installation of cables and tubes for experiments. The irradiation time can be set by means of a separate timer, so that the sources may be taken back into the rest position after irradiation, or they may be taken into the irradiation position after expiration of the time, as desired. The entire plant is automatically controlled and supervised by an interlock system. A system of radiation detectors and mechanical locks secures optimal safety of the plant against accidents. All important aggregates are supplied by a buffered battery so that, even in the case of a voltage breakdown, undisturbed operation is possible. In the case of defects in important parts of the plant, or wanton damage, an alarm system is triggered off- In acute danger this system immediately takes the sources back into their rest position or, if there is no acute danger, brings them up to the scientist to decide whether or not to continue irradiation. (author) [French] L'installation d'irradiation actuellement en construction a-ete specialement concue pour executer les recherches au titre du programme international d'irradiation des jus de fruits. L'installation consiste en deux casemates d'irradiation, l'une de 30 kCi et l'autre de 10 kCi. La premiere doit servir a irradier des jus de fruits en quantite necessaire pour les essais d'alimentation, et a faire des recherches sur la technologie des sources. L'autre est specialement destinee aux etudes microbiologiques et chimiques et offre les possibilites les plus variees de configuration et de position de la source en fonction des besoins de l'experience. L'ecran de protection, qui est construit en beton ordinaire d'une densite approximative de 2,4, donne a l'exterieur un debit de dose maximal de 0,2 mR/h- Les deux sources sont mises en position de repos dans un cylindre de plomb encastre dans le beton du blindage. Douze tubes d'acier inoxydable (six tubes pour la petite casemate) dans lesquels sont montes les barreaux de cobalt

  2. About the problem of the delays between particles belonging to the cosmic radiation; Sur le probleme des retards entre des particules appartenant au rayonnement cosmique

    Energy Technology Data Exchange (ETDEWEB)

    Rogozinski, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1953-07-01

    retard qui s'etablit entre deux particules de masse M appartenant a cette derniere espece est defini par la difference entre les temps qu'elles mettent pour franchir la meme distance. Dans le vide, les retards peuvent atteindre des valeurs quelconques, Mais, lorsque les particules se propagent dans un milieu absorbant, les retards tendent vers une limite bien definie quelles que soient les energies initiales des particules. On demontre que le retard maximum est donne par ({delta}t){sub max} {approx_equal} 0,6 E{sub 0} / cK{sub min}, ou E{sub 0} = Mc{sup 2} represente l'energie au repos de la particule et K{sub min} la perte minimum d'energie par cm de parcours dans le milieu donne. Par exemple, dans le cas des protons traversant differents milieux absorbants, les valeurs de ({delta}t){sub max} pour l'air (TPN), l'eau, l'Al et le Pb sont respectivement egales a 8,3.10{sup -6}, 9,7.10{sup -9}, 45.10{sup -9} et 1,6 10{sup -9} sec. Les valeurs correspondantes de ({delta}t){sub max} pour les electrons, sont de l'ordre de 10{sup -9} sec pour l'air et de l'ordre de 10{sup -12} sec pour les milieux condenses. Il en resulte que, si les particules appartenant a une gerbe manifestaient entre elles des retards superieurs a ceux qui vienent d'etre indiques, le fait constituerait une preuve suffisante de l'existence de particules lourdes au sein de la gerbe. Par ailleurs, la relation qui relie ({delta}t){sub max} a la masse M pourrait servir de base a une methode de spectrographie de masse des particules de grande energie. (auteur)

  3. SBIR PHASE I FINAL REPORT: Adoption of High Performance Computational (HPC) Modeling Software for Widespread Use in the Manufacture of Welded Structures

    Energy Technology Data Exchange (ETDEWEB)

    Brust, Frederick W. [Engineering Mechanics Corporation of Columbus (Emc2), Columbus, OH (United States); Punch, Edward F. [Engineering Mechanics Corporation of Columbus (Emc2), Columbus, OH (United States); Kurth, Elizabeth A. [Engineering Mechanics Corporation of Columbus (Emc2), Columbus, OH (United States); Kennedy, James C. [Engineering Mechanics Corporation of Columbus (Emc2), Columbus, OH (United States)

    2013-12-02

    element modeling. Finally, a plan for porting VFT onto the Ohio Supercomputer Center (OSC) through its hosted Manufacturing and Polymer Portal has been developed. This access route will permit SMEs to perform weld modeling to improve their competitiveness at a reasonable cost. All of these improvements are detailed in this repo

  4. Activity rhythms and the influence of some environmental variables on summer ungulate behaviour in Ordesa-Monte Perdido National Park

    Directory of Open Access Journals (Sweden)

    Aldezabal, A.

    1999-12-01

    pastoreo a primeras horas de la mañana y al atardecer, mientras que ovejas y rebecos presentan varios máximos de pastoreo a lo largo del día. Vacas y rebecos muestran claras relaciones entre varios tipos de actividad y los factores ambientales, mientras que la relación es menos aparente para ovejas y cabras. [fr] Nous avons étudié les rythmes d'activité journaliers ainsi que la distribution temporelle des différents types de comportement de quatre ongulés {vaches, brebis, chèvres et isards; ils utilisent la même unité pastorale (estive de Goriz dans les Pyrénées Centrales, au Parc National d'Ordesa. Aussi nous avons evalué l'influence de diverses variables environnenmentales (altitude, pente et recouvrement végétal sur le comportement des rumiants. Le pâturage devient l'activité prépondérante chez toutes les espèces: vaches 58%, brebis 53%, chèvres 55% et isards 68% du temps diurne. Les bovins passent plus de temps que les autres au repos (41% et les brebis dédient beaucoup de leur temps au déplacement (35%. Ces résultats suggèrent une relation inverse le poids vif et le temps du pâturage, phénomène déjà noté par d'autres. Bovins et caprins montrent deus périodes maximales de pâturage: le matin et la tombée du jour, tandis qu'ovins et isards présentent plusieurs pics du pâturage pendant la journée. Enfin bovins et isards montrent des relations significatives entre chacun des différents types de conduite et certains de l'environnement, tandis que ces rapports s'avèrent moins clairs pour les brebis et les caprins.

  5. Variations in hydraulic conductivity with scale of measurement during aquifer tests in heterogeneous, porous carbonate rocks

    Science.gov (United States)

    Schulze-Makuch, Dirk; Cherkauer, Douglas S.

    Previous studies have shown that hydraulic conductivity of an aquifer seems to increase as the portion of the aquifer tested increases. To date, such studies have all relied on different methods to determine hydraulic conductivity at each scale of interest, which raises the possibility that the observed increase in hydraulic conductivity is due to the measurement method, not to the scale. This study analyzes hydraulic conductivity with respect to scale during individual aquifer tests in porous, heterogeneous carbonate rocks in southeastern Wisconsin, USA. Results from this study indicate that hydraulic conductivity generally increases during an individual test as the volume of aquifer impacted increases, and the rate of this increase is the same as the rate of increase determined by using different measurement methods. Thus, scale dependence of hydraulic conductivity during single tests does not depend on the method of measurement. This conclusion is supported by 22 of 26 aquifer tests conducted in porous-flow-dominated carbonate units within the aquifer. Instead, scale dependency is probably caused by heterogeneities within the aquifer, a conclusion supported by digital simulation. All of the observed types of hydraulic-conductivity variations with scale during individual aquifer tests can be explained by a conceptual model of a simple heterogeneous aquifer composed of high-conductivity zones within a low-conductivity matrix. Résumé Certaines études ont montré que la conductivité hydraulique d'un aquifère semble augmenter en même temps que la partie testée de l'aquifère s'étend. Jusqu'à présent, ces études ont toutes reposé sur des méthodes de détermination de la conductivité hydraulique différentes pour chaque niveau d'échelle, ce qui a conduit à penser que l'augmentation observée de la conductivité hydraulique pouvait être due aux méthodes de mesure et non à l'effet d'échelle. Cette étude analyse la conductivité hydraulique par

  6. The Estimation of Internal Contamination with Uranium from Urine Analysis Results; Evaluation de la Contamination Interne par l'Uranium a Partir des Resultats de l'Analyse d'Urines; 041e 0426 0414 ; Evaluacion de la Contaminacion Interna con Uranio a Partir de los Resultados del Analisis de Orina

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, S. [Authority Health and Safety Branch, Radiological Protection Division, United Kingdom Atomic Energy Authority, Harwell, Berks. (United Kingdom)

    1964-11-15

    consideration principale dont il faut tenir compte est d'ordre non pas radiologique mais toxicologique, en raison des effets chimiques que produit l'uranium depose dans les reins. Une certaine quantite d'uranium se depose egalement dans le squelette mais, dans le cas de l'uranium naturel, la radioexposition du squelette est moins critique que des effets toxiques sur les reins. Dans le cas de composes solubles de l'uranium fortement enrichi ayant une activite specifique elevee, la consideration principale est d'ordre radiologique; les effets chimiques sur les reins sont moins limitatifs que la radioexposition du squelette, qui devient ainsi l'organe critique. Dans ce cas, il vaut mieux essayer d'evaluer la charge corporelle retenue et non la quantite d'uranium absorbee. On peut y parvenir en analysant des echantillons d'urines prelevees, non pas immediatement apres la contamination, mais apres un certain delaL Les echantillons preleves apres une periode de vacances sont probablement les meilleurs que l'on puisse obtenir en pratique, mais on peut avoir a se contenter d'echantillons preleves apres le repos hebdomadaire qui suit une semaine de travail dans une atmosphere chargee de poussieres d'uranium. (author) [Spanish] La causa mas corriente de contaminacion interna con uranio es la inhalacion de polvo de este elemento. Los compuestos solubles de uranio pasan rapidamente de los pulmones a la sangre y la mayor parte del uranio que penetra en el torrente circulatorio es excretado muy pronto por via urinaria. La cantidad de uranio soluble absorbida en el curso del trabajo se puede calcular a partir del contenido en uranio de muestras de orina tomadas inmediatamente despues del mismo. Los compuestos'solubles de uranio natural se caracterizan por el hecho de que la consideracion primordial no es de orden radiologico sino toxicologico, debido a los efectos quimicos del uranio depositados en los rinones Parte del uranio se deposita tambien en el esqueleto, pero la irradiacion del

  7. From Editor

    Directory of Open Access Journals (Sweden)

    Ugur Demiray

    2010-04-01

    difference between the two types of universities with regard to the availability of computers and the amount of ICT training and use.“PILOTING A VOCATIONAL E-COURSE AT A UK COLLEGE: Developing strategies to support non-native English speaking learners to complete the essay-type questions of their assignments” is the third paper for “Notes for Editor” section of TOJDE’s in this issue. It has written by Stavroula BIBILA from Istanbul Bilgi University,Turkey. Her paper presents a study of practice that was conducted during the piloting of a vocational (health care e-course at the Distance Learning department of a College of Further and Higher Education in England. The purpose of the study was to establish a course of action aiming to support non-native English speaking learners to successfully complete the essay-type questions of the e-course assignments. The findings includes implications for providing additional English for Speakers of Other Languages (ESOL support to distance learners, suggestions for further improvements to the e-course and recommendations for further research. The fourth note is very interesting that tells us a new application of Anadolu University Open Education Faculty’s on educating people as a digital photographer via distance method. A note is titled as “EDUCATING THE PEOPLE AS A DIGITAL PHOTOGRAPHER AND CAMERA OPERATOR VIA OPEN EDUCATION SYSTEM STUDIES FROM TURKEY: Anadolu University Open Education Faculty Case” which, written by Huseyin ERYILMAZ, Anadolu University, from the Faculty of Fine Arts and Department of Graphic Design,Turkey. The first article is a joint study which its authors are from neighbor of Turkey. The title is “Physical Educators’ Perspectives on Instructional Methodology Of Synchronous Distance Professional Development”, written by Kyriaki EMMANOUILIDOU, Panagiotis ANTONIOU and Vassiliki DERRI from the Department of Physical Education and Sport Science Democritus University of Thrace, Komotini, Greece. The

  8. Can the biogenicity of Europa's surfical sulfur be tested simultaneously with penetrators and ion traps?

    Science.gov (United States)

    Chela-Flores, J.; Bhattacherjee, A. B.; Dudeja, S.; Kumar, N.; Seckbach, J.

    2009-04-01

    miniaturized mass spectrometry. From these arguments we may conclude that a penetration of measuring instruments (penetrators) into the icy surface of Europa just beyond the few millimeters beyond the stopping-depth would be sufficient for an accurate estimate of the delta-34 S parameter. This would be a possible way for rejecting, or supporting, the hypothesis of biogenicity of the Europan sulfur patches. The fact that missions such as LAPLACE, or others, can envisage, and undertake, such measurements (in the foreseeable future) is of the utmost importance for astrobiology's most significant question: Are there other environments in our own Solar System where we could settle the question of habitability, by making use of the available technologies? These results suggest that with the optimum stopping-depth we have calculated, sulfate-reducing bacteria would leave a measurable trace of their activity that is not affected by the harsh external environment. In addition, we have related sulfur transport in microbial mats that are known to take place in the Antarctica subglacial lakes with a mechanism that might rationalize what is taking place in the sulfur patches of the icy surface of Europa. Lake Vostok has given us preliminary hints from microorganisms retrieved from the accreted ice that lies just above its still-unexplored liquid water. References (*) Blanc, M. and the LAPLACE consortium (2008) LAPLACE: a mission to Europa and the Jupiter System, Astrophysical Instruments and Methods, in press, http://www.ictp.it/~chelaf/ss186.html,Team Members http://www.ictp.it/~chelaf/ss164.html. Chela-Flores J. and Kumar N. (2008) Returning to Europa: Can traces of surficial life be detected? International Journal of Astrobiology 7: (3), 263-269, http://journals.cambridge.org/repo_A28gqjIw Chyba, C. (2000) Energy for microbial life on Europa, Nature 403: 381-383. Dudeja, S., Bhattacherjee, A. B. and Chela-Flores, J. (2009) Microbial mats in Antarctica as models for the search of life on

  9. Electrolyte Concentrations of Intra- and Extracellular Compartments in Some Internal Diseases; Concentration des Electrolytes dans les Compartiments Intra- et Extracellulares, dans Certaines Maladies Internes; ВНУТРИКЛЕТОЧНАЯ И ВНЕКЛЕТОЧНАЯ КОНЦЕНТРАЦИЯ ЭЛЕКТРОЛИТОВ ПРИ НЕКОТОРЫХ ВНУТРЕННИХ ЗАБОЛЕВАНИЯХ; Concentraciones de Electrolitos en Comp Artimientos Intra y Extracelulares en Algunas Enfermedades Internas

    Energy Technology Data Exchange (ETDEWEB)

    Itahara, K.; Ito, K.; Tominaga, T.; Jimbo, T.; Sato, T. [Tohoku University, Sendai (Japan)

    1963-03-15

    extracellulaire etait de 42,8 et 48,7, respectivement, pendant l'attaque qui avait ete provoquee, tandis que l'elimination de potassium par l'urine n'augmentait pas. Il a ete demontre qu'un transfert de mineraux s'etait produit entre les liquides extiacellulaire et intracellulaire. En provoquant une paralysie complete ou incomplete par le glucose et l'insuline chez des malades ayant deja subi des attaques de paralysie, on a constate dans cinq cas sur huit que le rapport des concentrations depassait 38,0 pendant chacune des attaques. On a aussi constate que l'augmentation de cette valeur etait liee a la gravite de la paralysie. La pathogenese de la paralysie semble donc due non seulement a une augmentation du potentiel de repos des muscles mais aussi a la difference entre les concentrations intra- et extracellulaites du potassium. Tableau I indique les differentes compositions electrolytiques enregistrees dans ces maladies. (author) [Spanish] En la tercera Conferencia sobre Radioisotopos que se celebro en 1959 en el Japon, los autores presentaron una memoria sobre la medicion de la masa total de agua del organismo (espacio D{sub 2}O), del volumen de los fluidos extracelulares (espacio rrianitol), y de las cantidades totales de sodio y potasio intercambiables en enfermos edematosos e hipertensos. La memoria actual describe el estudio de las concentraciones de sodio y potasio en los fluidos extra e intracelulares empleando {sup 24}Na y {sup 42}K en sujetos que padecen hipertension, aldosteronismo primario y paralisis periodica. En 10 hipertensos, el valor medio de la concentracion de sodio intercambiable ( Nae) - expresada en mEq/kg de peso corporal - era de 45,2 (valor normal: 39,5), en tanto que en 14 otros enfermos, el valor medio de la concentracion de potasio intercambiable (Ke) ascendia a 32,5 (valor normal: 42,7). La razon de las concentraciones intracelulares K/Na era de 1,8 (valor normal: 2,9) y la razon de las concentraciones intra y extra- celulares de potasio ascendia a

  10. Sb{sup III} - Sb{sup V} Exchange Reaction in Hydrochloric: Acid Solutions; Echange Sb{sup III}-Sb{sup V} dans des Solutions d'Acide Chlorhydrique; Reaktsiya obmena Sb(III) - Sb(V) v rastvorakh khloristovodorodnoj kisloty; Intercambio Sb{sup III}-Sb{sup V} en Soluciones de HCl

    Energy Technology Data Exchange (ETDEWEB)

    Kambara, T.; Yamaguchi, K.; Yasuba, S. [Shizuoka University, Shizuoka City (Japan)

    1965-10-15

    } etait de 4,5 * 10{sup -6} mole * l{sup -1}; dans le deuxieme (apres 24 heures de repos), R{sub 2} etait de 1,2 * 10{sup -6} mole * l{sup -1} * min{sup -1}. L'energie d'activation etait respectivement de 12,2 kcal/mole et 19,1 kcal/mole. Les etudes spectrophotometriques ont permis d'etablir que les SbV du premier type etait constitues principalement par SbCl{sub 6}{sup -} et ceux du deuxieme type, par SbCl{sub 4}(OH){sub 2}{sup -}, etc. En dehors de ces faits, les auteurs n'ont releve aucune influence de la forme de Sb{sup III} sur la vitesse d'echange. Une augmentation beaucoup plus forte de la vitesse d'echange a ete observee lorsque la concentration en HCl de la solution d'antimoine etait 0,8M et la concentration en chlorure etait portee a 3.0M par addition de LiCl. Il est a noter qu'une augmentation forte et quasi lineaire de la vitesse a ete observee pour des concentrations en chlorure allant jusqu'a 2,0M. Etant donne que ce phenomene a ete observe pour une concentration constante en ions hydrogene, on peut penser que les atomes de chlorure interviennent comme atomes de pontage du compose intermediaire en vue de l'echange d'antimoine. (author) [Spanish] Empleando {sup 124}Sb como indicador, los autores estudiaron la reaccion de intercambio Sb{sup III} - Sb{sup V} en soluciones diluidas de HCl y en particular los efectos de la concentracion de HCl y de la forma quimica del Sb sobre la velocidad de intercambio. La concentracion de HCl de las soluciones de antimonio ((Sb{sup III}) =(Sb{sup V}) = 6.8 x 10{sup -4}M) se modifico entre 0,8 y 4,0M y el tiempo de semi-intercambio se midio trazando la curva representativa de log(1 - F) en funcion del tiempo t, con el fin de calcular la velocidad de intercambio suponiendo que se trata de una reaccion de segundo orden. Se comprobo que la velocidad de intercambio aumentaba netamente al elevar la concentracion de HCl (de 0,8 a 2,0M a 25 Degree-Sign C) y alcanzaba un valor maximo a 2,0M a partir del cual volvia a diminuir si la

  11. Contributo dos músculos respiratórios para a fisiopatologia da hipercápnia na doença pulmonar obstrutiva crónica estabilizada

    Directory of Open Access Journals (Sweden)

    Cristina Bárbara

    2001-05-01

    respiratoire, les échanges gazeux et Ia force des muscles respiratoires, dans 50 malades avec B.P.C.O. (27 normocapniques et 23 hypercapniques et 17 sujets contrôles, sans pathologie cardio-respiratoire. Les resultats des malades normocapniques ont été comparés avec les des hypercapniques et aussi les résultats de ces deux groupes avec le groupe contrôle.Les volumes pulmonaires ont été étudiés par pléthismographie. Le volume gazeux thoracique (TGV a été utilisé comme Ia meilleure approximation de Ia capacité résiduelle fonctionnelle (FRC. L’obstruction des voies aériennes a été evaluee par Ia determination des debits forces et par Ia conductance specifique (SGaw. La détermination au repos, de Ia pression d’occlusion (P0,l, de Ia ventilation minute (V’E et aussi de Ia variation de ces variables après stimulation avec CO2 ont compris l’etude du controle de Ia ventilation. Le mode respiratoire a été évalue par Ia détermination de Ia durée du temps inspiratoire (Ti, de Ia duree de cycle respiratoire total (Ttot, du volume courant (VT, et du rapport volume de l’espace mort sur le volume courant (VD/VT. Les échanges gazeux ont été évalues par Ia détermination du coefficient de transfert pour le monoxyde de carbone (TL/NA et aussi par Ia gazométrie artérielle. Nons avons etudie aussi les muscles respiratoires avec des methodes dependants et non dependants de l'effort. Les pressions maximales statiques au niveau de Ia bouche et Ia technique du sniff nasal avec Ia détermination des pressions au niveau nasal, esophagienne et gastrique ont été les méthodes dependantes de I’effort. La stimulation magnetique cervicale a été l’unique technique non dépendant de I’effort.Les malades hypercapniques ont présenté une obstruction et une hyperinsuffiation plus accentué quand on les compare avec le groupe des normocapniques. lis