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Sample records for replant disease prd

  1. Tractor-mounted, GPS-based spot fumigation system manages Prunus replant disease

    Science.gov (United States)

    Our research goal was to use recent advances in global positioning system (GPS) and computer technology to apply just the right amount of fumigant where it is most needed (i.e., in a small target treatment zone in and around each tree replanting site) to control Prunus replant disease (PRD). We deve...

  2. Integration of apple rootstock genotype with reduced Brassica seed meal application rates for replant disease control

    Science.gov (United States)

    Pre-plant soil application of Brassica seed meal (SM) formulations can provide fumigant level control of apple replant disease. However, due to high cost of the SM treatment relative to non-tarped soil fumigation, reduced application rates would likely accelerate commercial adoption of this technolo...

  3. Progress in Brassicaceae seed meal formulation and application for replant disease control in organic apple orchards

    Science.gov (United States)

    Brassicaceae seed meals when used independently do not provide uniform or sufficient control of the pathogen complex that incites apple replant disease. Trials were established at multiple sites (STM, SR and Tukey orchards) in Washington State to evaluate the efficacy of seed meal formulations for ...

  4. How to Plant Apple Trees to Reduce Replant Disease in Apple Orchard: A Study on the Phenolic Acid of the Replanted Apple Orchard.

    Science.gov (United States)

    Yin, Chengmiao; Xiang, Li; Wang, Gongshuai; Wang, Yanfang; Shen, Xiang; Chen, Xuesen; Mao, Zhiquan

    2016-01-01

    Apple replant disease (ARD) is an important problem in the production of apple. The phenolic acid is one of the causes of ARD. How phenolic acid affects the ARD was not well known. In this study, we analyzed the type, concentration and annual dynamic variation of phenolic acid in soil from three replanted apple orchards using an accelerated solvent extraction system with high performance liquid chromatography (ASE-HPLC). We found that the type and concentration of phenolic acid were significantly differed among different seasons, different sampling positions and different soil layers. Major types of phenolic acid in three replanted apple orchards were phlorizin, benzoic acid and vanillic aldehyde. The concentration of phenolic acid was highest in the soil of the previous tree holes and it was increased from the spring to autumn. Moreover, phenolic acid was primarily distributed in 30-60 cm soil layer in the autumn, while it was most abundant in 0-30 cm soil layer in the spring. Our results suggest that phlorizin, benzoic acid and vanillic aldehyde may be the key phenolic acid that brought about ARD in the replanted apple orchard.

  5. How to Plant Apple Trees to Reduce Replant Disease in Apple Orchard: A Study on the Phenolic Acid of the Replanted Apple Orchard

    Science.gov (United States)

    Yin, Chengmiao; Xiang, Li; Wang, Gongshuai; Wang, Yanfang; Shen, Xiang; Chen, Xuesen; Mao, Zhiquan

    2016-01-01

    Apple replant disease (ARD) is an important problem in the production of apple. The phenolic acid is one of the causes of ARD. How phenolic acid affects the ARD was not well known. In this study, we analyzed the type, concentration and annual dynamic variation of phenolic acid in soil from three replanted apple orchards using an accelerated solvent extraction system with high performance liquid chromatography (ASE-HPLC). We found that the type and concentration of phenolic acid were significantly differed among different seasons, different sampling positions and different soil layers. Major types of phenolic acid in three replanted apple orchards were phlorizin, benzoic acid and vanillic aldehyde. The concentration of phenolic acid was highest in the soil of the previous tree holes and it was increased from the spring to autumn. Moreover, phenolic acid was primarily distributed in 30–60 cm soil layer in the autumn, while it was most abundant in 0–30 cm soil layer in the spring. Our results suggest that phlorizin, benzoic acid and vanillic aldehyde may be the key phenolic acid that brought about ARD in the replanted apple orchard. PMID:27907081

  6. Transcriptomic analysis of molecular responses in Malus domestica 'M26' roots affected by apple replant disease.

    Science.gov (United States)

    Weiß, Stefan; Bartsch, Melanie; Winkelmann, Traud

    2017-06-01

    Gene expression studies in roots of apple replant disease affected plants suggested defense reactions towards biotic stress to occur which did not lead to adequate responses to the biotic stressors. Apple replant disease (ARD) leads to growth inhibition and fruit yield reduction in replanted populations and results in economic losses for tree nurseries and fruit producers. The etiology is not well understood on a molecular level and causal agents show a great diversity indicating that no definitive cause, which applies to the majority of cases, has been found out yet. Hence, it is pivotal to gain a better understanding of the molecular and physiological reactions of the plant when affected by ARD and later to overcome the disease, for example by developing tolerant rootstocks. For the first time, gene expression was investigated in roots of ARD affected plants employing massive analysis of cDNA ends (MACE) and RT-qPCR. In reaction to ARD, genes in secondary metabolite production as well as plant defense, regulatory and signaling genes were upregulated whereas for several genes involved in primary metabolism lower expression was detected. For internal verification of MACE data, candidate genes were tested via RT-qPCR and a strong positive correlation between both datasets was observed. Comparison of apple 'M26' roots cultivated in ARD soil or γ-irradiated ARD soil suggests that typical defense reactions towards biotic stress take place in ARD affected plants but they did not allow responding to the biotic stressors attack adequately, leading to the observed growth depressions in ARD variants.

  7. Evaluating systemic semi-selective chemicals for the management of apple replant disease in fumigated and non-fumigated orchards systems

    Science.gov (United States)

    Apple Replant Disease (ARD) is a phenomenon where apple trees are stunted when replanted onto old apple soil, as the result of apple monoculture resulting in soil microbial changes where pathogenic and parasitic organism s predominate. The main soilborne organisms that cause ARD include oomycetes, f...

  8. Apple replant disease and the –omics: interaction of apple rootstock metabolome and the soil microbiome

    Science.gov (United States)

    Apple replant disease (ARD) negatively impacts tree health and reduces crop yield in new orchard plantings. Use of tolerant rootstock cultivars can diminish the growth limiting effects of ARD; however specific rootstock attributes enabling ARD tolerance are not understood. Systems biology tools were...

  9. A bio-product as alternative to methyl bromide for replant disease control on strawberry

    Institute of Scientific and Technical Information of China (English)

    Yu ZHANG; Tongle HU; Lijing JI; Keqiang CAO

    2008-01-01

    Pre-plant soil fumigation with methyl bromide (MB) is a standard practice for controlling soil-borne diseases especially for strawberry diseases. However, the application of MB will be forbidden in China in the year 2015. For this reason, a bio-product named Kangdi 3 was tested as an alternative to MB in strawberry greenhouses in Mancheng (Hebei Province) and Donggang (Liaoning province), China in 2005 and 2006. Methyl bromide at a normal dosage of 500 kg/hm2 and Kangdi 3 at three dosages of 750, 1500 and 2250 kg/hm2 were tested. Plots without any treatment were used as the control. During the growing stage, assessments were made on fungal communities in rhizosphere, growth status of strawberry, the disease levels on roots as well as the yields. Results showed that Kangdi 3 significantly reduced the quantity of fungi and the disease index, while enhancing strawberry growth and the yields compared with the untreated control. Therefore, Kangdi 3 is a great potential substitute for methyl bromide to control replant diseases in strawberry.

  10. D3.1 Deliverable. GDAR activity on Evaluation of biological active Formulates and strains for the biological control of replant disease

    OpenAIRE

    KAYMAK, Suat

    2014-01-01

    This report presents the GDAR activity on evaluation of biological active Formulates and strains for the biological control of apple replant disease. Eleven products were evaluated with a plant growth assay in pot using plantlets of MM104 rootstock to evaluate their effectivenes in controlling Phythophtora cactorum. The trial was perfotrmed with soil artificially inoculated with the pathogen.

  11. Unfavorable results in replantation

    OpenAIRE

    Abraham G Thomas

    2013-01-01

    Reattachment of amputated parts of the body (Replantation) has become a reality since the first arm replant was carried out six decades ago. Failures were not uncommon in the beginning, leading on to the analysis of the problem and refinements in technique. Improvements in sutures, instrumentation and better microscopes further helped the surgeons to do replantation with better finesse and functional results. Evaluation of results and particularly failure and long term results help the younge...

  12. Incidence and Pathogenicity of Plant-Parasitic Nematodes Associated with Blueberry (Vaccinium spp.) Replant Disease in Georgia and North Carolina

    Science.gov (United States)

    Jagdale, Ganpati B.; Holladay, Ted; Brannen, P. M.; Cline, W. O.; Agudelo, P.; Nyczepir, A. P.; Noe, J. P.

    2013-01-01

    Blueberry replant disease (BRD) is an emerging threat to continued blueberry (Vaccinium spp.) production in Georgia and North Carolina. Since high populations of ring nematode Mesocriconema ornatum were found to be associated with commercially grown blueberries in Georgia, we hypothesized that M. ornatum may be responsible for predisposing blueberry to BRD. We therefore tested the pathogenicity of M. ornatum on 10-wk-old Rabbiteye blueberries (Vaccinium virgatum) by inoculating with initial populations (Pi) of 0 (water control), 10, 100, 1,000. and 10,000 mixed stages of M. ornatum/pot under both greenhouse (25 ± 2°C) and field microplot conditions. Nematode soil population densities and reproduction rates were assessed 75, 150, 225, and 255, and 75, 150, 225, and 375 d after inoculation (DAI) in both the greenhouse and field experiments, respectively. Plant growth parameters were recorded in the greenhouse and field microplot experiments at 255 and 375 DAI, respectively. The highest M. ornatum population density occurred with the highest Pi level, at 75 and 150 DAI under both greenhouse (P Xiphinema spp. Paratrichodorus spp. was also found only in Georgia. In Georgia, our results indicate that blueberry is a host for M. ornatum and its relationship to BRD warrants further investigation. PMID:23833323

  13. Digit and hand replantation.

    Science.gov (United States)

    Beris, Alexandros E; Lykissas, Marios G; Korompilias, Anastasios V; Mitsionis, Gregory I; Vekris, Marios D; Kostas-Agnantis, Ioannis P

    2010-09-01

    For the past 45 years, the advent of microsurgery has led to replantation of almost every amputated part such as distal phalanx, finger tip, etc. Replantation of digits and hand can restore not only circulation, but also function and cosmetic of the amputated part. The goals of replantation are to restore circulation and regain sufficient function and sensation of the amputated part. Strict selection criteria are necessary to optimize the functional result. The management of this type of injuries includes meticulous preoperative management, microsurgical experience and continuous postoperative care. Among various factors influencing the outcome, the most important are the type and the level of injury, ischemia time, history of diabetes, age, sex, and smoking history. During the replantation procedure, bone stabilization, tendon repair, arterial anastomoses, venous anastomoses, nerve coaptation, and skin coverage should be performed. All structures should be repaired primarily, unless a large nerve gap or a flexor tendon avulsion injury is present. Adequate postoperative evaluation is mandatory to avoid early or late complications. To improve functional results, many replantation patients may need further reconstructive surgery.

  14. Unfavorable results in replantation

    Directory of Open Access Journals (Sweden)

    Abraham G Thomas

    2013-01-01

    Full Text Available Reattachment of amputated parts of the body (Replantation has become a reality since the first arm replant was carried out six decades ago. Failures were not uncommon in the beginning, leading on to the analysis of the problem and refinements in technique. Improvements in sutures, instrumentation and better microscopes further helped the surgeons to do replantation with better finesse and functional results. Evaluation of results and particularly failure and long term results help the younger surgeons to learn from the difficulties faced earlier to do better in the future. An attempt is made to list various aspects of replantation experienced by the author during the past 30 years, particularly in reference to unfavorable results, which had been occasionally total failure, or a partial failure, with poor function and cosmesis due to infection. An insensate limb with poor function is the result of inadequate or improper nerve coaptation or infection destroying the whole repair. It is apt to mention that infection is mostly the result of poor vascularity due to devitalized tissue. Difficulties arise often in identifying the viable tissue, particularly while debriding in the distal amputated part since there is no bleeding. Experience counts in this, specifically to identify the viable muscle. The factors that may lead to complications are listed with remarks to avoid them.

  15. Unfavorable results in replantation.

    Science.gov (United States)

    Thomas, Abraham G

    2013-05-01

    Reattachment of amputated parts of the body (Replantation) has become a reality since the first arm replant was carried out six decades ago. Failures were not uncommon in the beginning, leading on to the analysis of the problem and refinements in technique. Improvements in sutures, instrumentation and better microscopes further helped the surgeons to do replantation with better finesse and functional results. Evaluation of results and particularly failure and long term results help the younger surgeons to learn from the difficulties faced earlier to do better in the future. An attempt is made to list various aspects of replantation experienced by the author during the past 30 years, particularly in reference to unfavorable results, which had been occasionally total failure, or a partial failure, with poor function and cosmesis due to infection. An insensate limb with poor function is the result of inadequate or improper nerve coaptation or infection destroying the whole repair. It is apt to mention that infection is mostly the result of poor vascularity due to devitalized tissue. Difficulties arise often in identifying the viable tissue, particularly while debriding in the distal amputated part since there is no bleeding. Experience counts in this, specifically to identify the viable muscle. The factors that may lead to complications are listed with remarks to avoid them.

  16. Tetanus following replantation of an amputated finger: a case report

    Directory of Open Access Journals (Sweden)

    Hayashida Kenji

    2012-10-01

    Full Text Available Abstract Introduction Tetanus is an infectious disease caused by tetanus toxin produced by Clostridium tetani and induces severe neurological manifestations. We treated a patient who developed tetanus during hospitalization for replantation of an amputated finger. To the best of our knowledge, this is the first published case report of such an entity. Case presentation A 49-year-old Japanese man had an amputation of his right middle finger at the distal interphalangeal joint region in an accident at work. His middle finger was successfully replanted, but his fingertip was partially necrotized because of crushing and so additional reconstruction with a reverse digital arterial flap was performed 15 days after the injury. Tetanus developed 21 days after replantation of the middle finger, but symptoms remitted via rapid diagnosis and treatment. Conclusions In replantation after finger trauma with exposure of nerve and blood vessel bundles, concern over injuring nerves and blood vessels may prevent irrigation and debridement from being performed sufficiently; these treatments may have been insufficiently performed in this patient. It is likely that the replanted middle finger partially adhered, and Clostridium tetani colonized the partially necrotized region. Even when there is only limited soil contamination, administration of tetanus toxoid and anti-tetanus immunoglobulin is necessary when the fingers are injured outdoors and the finger nerves and blood vessels are exposed. The drugs should be administered just after replantation if the finger has been amputated. However, if clinicians pay attention to the possibility of tetanus development, treatment can be rapidly initiated.

  17. Successful microsurgical replantation of an amputated penis

    Directory of Open Access Journals (Sweden)

    Sanchit Garg

    2016-01-01

    Full Text Available Penile amputation is an uncommon injury for which immediate surgical replantation is warranted. Microsurgical replantation is the “standard” method for penile replantation. Early replantation yields a high success and low complication rate. We report a case of a 34-year-old male who presented with amputation at the proximal penile shaft which was successfully replanted using microsurgical techniques. Minor skin necrosis was noted post-operatively which was debrided and covered with skin graft. Follow-up at 6 months showed satisfactory cosmetic appearance, normal voiding, return of sensations and erectile function. The level of evidence was V.

  18. Spatial Distribution of Coffee Wilt Disease Under Roguing and Replanting Conditions: A Case Study from Kaweri Estate in Uganda.

    Science.gov (United States)

    Pinard, F; Makune, S E; Campagne, P; Mwangi, J

    2016-11-01

    Based on time and spatial dynamic considerations, this study evaluates the potential role of short- and long-distance dispersal in the spread of coffee wilt disease (CWD) in a large commercial Robusta coffee estate in Uganda (Kaweri, 1,755 ha) over a 4-year period (2008 to 2012). In monthly surveys, total disease incidence, expansion of infection foci, and the occurrence of isolated infected trees were recorded and submitted to spatial analysis. Incidence was higher and disease progression faster in old coffee plantings compared with young plantings, indicating a lack of efficiency of roguing for reducing disease development in old plantings. At large spatial scale (approximately 1 km), Moran indices (both global and local) revealed the existence of clusters characterized by contrasting disease incidences. This suggested that local environmental conditions were heterogeneous or there were spatial interactions among blocks. At finer spatial scale (approximately 200 m), O-ring statistics revealed positive correlation between distant infection sites across distances as great as 60 m. Although these observations indicate the role of short-distance dispersal in foci expansion, dispersal at greater distances (>20 m) appeared to also contribute to both initiation of new foci and disease progression at coarser spatial scales. Therefore, our results suggested the role of aerial dispersal in CWD progression.

  19. Function of the replanted spleen in dogs

    Energy Technology Data Exchange (ETDEWEB)

    Velcek, F.T.; Kugaczewski, J.T.; Jongco, B.; Shaftan, G.W.; Rao, P.S.; Schiffman, G.; Kottmeier, P.K.

    1982-06-01

    The function of replanted splenic fragments was studied by comparing three groups of five dogs each, one group with intact spleens; one, post-splenectomy; and one with splenic replantation. Fifteen fragments were implanted into the omentum. Howell-Jolly bodies appeared after splenectomy but cleared in the replanted group after several months. /sup 125/I-tagged attenuated pneumococcal clearance studies showed a significant difference between control and replanted group compared with the splenectomized group. The increase of pneumococcal antibody titers after vaccination differed significantly between the splenectomized and the replanted group. All replanted fragments were viable and showed growth over a 2-year period. These studies demonstrate that omental replantation of the canine spleen leads to the maintenance of certain functional splenic parameters comparable to the normal spleen which are significantly different from the splenectomized animal.

  20. Digit Replantation The First 50 Years.

    Science.gov (United States)

    Hadley, Scott R; Capo, John T

    2015-06-01

    Since the first successful digit replantation by Japanese surgeons Komatsu and Tamai, the past half century has seen the field of digit replantation in the USA experience exponential growth followed by a steady decline in volume of cases and percentage of successful viable digits. The initial enthusiasm and technical progress of digital replantation has been tempered by mediocre functional outcomes, rising healthcare costs, and limited healthcare resources. The history and approach to digit replantation is reviewed and highlights the likely push toward the development of regional replant centers staffed by highly skilled teams to improve the functional outcomes following these complex procedures. More than 50 years have passed since the first successful digit replantation by Komatsu and Tamai who replanted a sharply amputated thumb in a 28-year-old male at the metacarpal-phalangeal joint level in a 4.5 hour procedure. Two arteries and 2 veins were anastomosed using 8-0 monofilament nylon and 7-0 braided silk suture. The patient remained in the hospital for 40 days and did not return to work for 4 months. News of this triumph of microvascular skill was heralded throughout the world as the first successful replantation of a completely amputated digit. Over the past half century, the field of digit replantation in the USA experienced exponential growth followed by a steady decline in volume of cases and percentage of successful viable digits. The initial enthusiasm and technical progress of digital replantation has been tempered by mediocre functional outcomes, rising healthcare costs, and limited healthcare resources. In the next 50 years, it is possible that the majority of digit replantation procedures in the USA may be performed in tertiary centers or regional replant centers by highly skilled teams.

  1. Delayed replantation of avulsed teeth

    Directory of Open Access Journals (Sweden)

    Adil N

    2007-05-01

    Full Text Available Dental injuries are very common and their extent has been classified by Ellis. Avulsion of tooth is a grievous injury and ranges from 1-16% among the traumatic injuries, of which maxillary anterior are commonest. Reimplantation of avulsed teeth is a standard procedure. However, it has certain limitations. Most often their management is very challenging. In this case report we are presenting the management of maxillary incisors by replantation after 36 hrs in a 12 year old girl.

  2. Replantation (Finger, Hand, or Arm)

    Science.gov (United States)

    ... per month. The number of inches from the injury to the tip of a finger gives the minimum number of months after which ... Replantation refers to the surgical reattachment of a finger, hand, or arm that has been completely cut from a person’s ... 2017 by American Society for Surgery of the Hand × Search Tips Tip 1: Start with the basics like "carpal ...

  3. Replantation of ring avulsion amputations

    Directory of Open Access Journals (Sweden)

    Sabapathy R

    2003-01-01

    Full Text Available Replantation of ring avulsion injuries is a challenge because of the long segment damage to the vessels and intrinsic damage caused to soft tissues at the proximal edge of the amputation. Eight patients with total ring avulsion amputations underwent microsurgical replantation in the period 1994 to 2002. Arterial repair was done by direct vessel suture in three patients, interposition vein grafts in two and cross anastomosis of the digital arteries in three patients. Venous anastomosis was carried out by mobilization and direct suture in seven patients and vessel transfer from the adjacent finger in one patient. Seven of the eight replantations were successful, while one patient had a partial failure. At a minimum follow-up of one year, these patients showed good functional and cosmetic recovery. All successful patients were happy with the outcome and none have requested for amputation, even those whose results were not functionally adequate. However, in addition to technical factors, it is important to evaluate the patient's motivation to undergo not only the long surgery, but also multiple secondary procedures and regular supervised physiotherapy. We also describe a simple method which prevents the soft tissues inside the degloved digit from becoming wrapped around the K wire during bony fixation, thus making one step of this technically challenging procedure a little easier.

  4. Replantation of an amputated upper lip.

    Science.gov (United States)

    Husami, T W; Cervino, A L; Pennington, G A; Douglas, B K

    1992-01-01

    Soft tissue defects of the face are a difficult reconstructive problem. Replantation of large amputated segments of the face has been rarely successful and has lagged well behind extremity trauma due in part to the relative rarity of these defects. Presented is a case of successful microvascular replantation of half of the upper lip after a dog bite.

  5. Replantation of upper extremity, hand and digits.

    Science.gov (United States)

    Bumbasirević, Marko Z; Vucković, Cedo D; Vucetić, Cedomir; Manojlović, Radovan; Andjelkovic, Sladjana Z; Palibrk, Tomislav D; Milutinović, Suzana M; Raspopović, Emilija Dubljanin

    2013-01-01

    Replantation is defined as reattachment of the part that has been completely amputated and there is no connection between the severed part and the patient. In Boston in 1962 Malt successfully replanted a completely amputated arm of a 12-year-old boy. Komatsu and Tamai reported the first successful replantation of an amputated digit by microvascular technique. There are no strict indications and contraindications for replantation. It's on surgeon to explain to the patient the chances of success of viability, expected function, length of operation, hospitalization and long rehabilitation protocol. Survival and useful function in replantation of upper extremity amputations is questionable. Success depends on microvascular anastomoses, but the final function is related with tendon, nerve, bone and joint repair.

  6. Illumina amplicon sequencing of 16S rRNA tag reveals bacterial community development in the rhizosphere of apple nurseries at a replant disease site and a new planting site.

    Directory of Open Access Journals (Sweden)

    Jian Sun

    Full Text Available We used a next-generation, Illumina-based sequencing approach to characterize the bacterial community development of apple rhizosphere soil in a replant site (RePlant and a new planting site (NewPlant in Beijing. Dwarfing apple nurseries of 'Fuji'/SH6/Pingyitiancha trees were planted in the spring of 2013. Before planting, soil from the apple rhizosphere of the replant site (ReSoil and from the new planting site (NewSoil was sampled for analysis on the Illumina MiSeq platform. In late September, the rhizosphere soil from both sites was resampled (RePlant and NewPlant. More than 16,000 valid reads were obtained for each replicate, and the community was composed of five dominant groups (Proteobacteria, Acidobacteria, Bacteroidetes, Gemmatimonadetes and Actinobacteria. The bacterial diversity decreased after apple planting. Principal component analyses revealed that the rhizosphere samples were significantly different among treatments. Apple nursery planting showed a large impact on the soil bacterial community, and the community development was significantly different between the replanted and newly planted soils. Verrucomicrobia were less abundant in RePlant soil, while Pseudomonas and Lysobacter were increased in RePlant compared with ReSoil and NewPlant. Both RePlant and ReSoil showed relatively higher invertase and cellulase activities than NewPlant and NewSoil, but only NewPlant soil showed higher urease activity, and this soil also had the higher plant growth. Our experimental results suggest that planting apple nurseries has a significant impact on soil bacterial community development at both replant and new planting sites, and planting on new site resulted in significantly higher soil urease activity and a different bacterial community composition.

  7. Successful replantation in 10-digit complete amputations.

    Science.gov (United States)

    Qing-tai, L; Chang-qing, J Z; Ke-fei, Y; Sha-ling, C; Jan, L; Zun-ying, L

    1996-08-01

    We report a case of successful replantation of 10-digit complete amputations. The conditions of the wounds over the ends of the 10 amputated digits are bound to vary; some are too severe to be replanted, while others may be light and easy for replantation. We reported a case of 10-digit complete amputations, with severe avulsion injuries over four fingers. Appropriate measures were taken during surgery, and the replanted digits all survived. The replantation operation was done by a team of surgeons, although the surgeons were physically challenged by the long and difficult procedures. However, it was the great pleasure of the surgeons to work hard and whole-heartedly for the benefit of the patient. Postoperative physiotherapy and exercises were done. After 6 months, the functions of both hands had been largely recovered. Complete amputations of 10 digits as a rule result in multiple complicated wounds. The replantation procedure for these conditions is not an easy endeavor because there are numerous blood vessels that need to be anastomosed, the time of the operation will be dreadfully long, and also there is the danger of the occurrence of vascular crises during the postoperative period. It is difficult to achieve successful survival of all 10 amputated digits after replantation.

  8. Delayed replantation after prolonged dry storage

    Directory of Open Access Journals (Sweden)

    Anita Rao

    2014-01-01

    Full Text Available Management of tooth avulsion in the permanent dentition often presents a challenge. Definitive treatment planning and consultation with specialists is seldom possible at the time of emergency treatment. Replantation of the avulsed tooth can restore esthetic appearance and occlusal function shortly after the injury. This article describes the management of a patient with an avulsed maxillary permanent incisor that had been air-dried for about 40 h. The replanted incisor retained its esthetic appearance and functionality 1 year after replantation, yet the long-term prognosis is not good because of progressive replacement root resorption.

  9. Partial Root-Zone Drying (PRD) Feasibility on Potato in a Sub-Humid Climate

    DEFF Research Database (Denmark)

    Battilani, A; Jensen, C R; Liu, F;

    2014-01-01

    A field experiment was carried out in Northern Italy, within the frame of the EU project SAFIR, to test the feasibility of partial root-zone drying (PRD) irrigation management in potatoes and to compare the PRD irrigation strategy with regulated deficit irrigation (RDI). PRD increased total and f...... not steadily and not sufficiently to overcome the higher irrigation system and management costs.......A field experiment was carried out in Northern Italy, within the frame of the EU project SAFIR, to test the feasibility of partial root-zone drying (PRD) irrigation management in potatoes and to compare the PRD irrigation strategy with regulated deficit irrigation (RDI). PRD increased total...... Efficiency (WUE, NUE) were similar between irrigation treatments. The income for each cubic meter of water or kg of nitrogen was highly variable and not statistically different between PRD and RDI. Crop gross margin per hectare shows a tendency to increase with PRD (average +256 euro ha-1), although...

  10. Partial Root-Zone Drying (PRD) Feasibility on Potato in a Sub-Humid Climate

    DEFF Research Database (Denmark)

    Battilani, A; Jensen, C R; Liu, F

    2014-01-01

    A field experiment was carried out in Northern Italy, within the frame of the EU project SAFIR, to test the feasibility of partial root-zone drying (PRD) irrigation management in potatoes and to compare the PRD irrigation strategy with regulated deficit irrigation (RDI). PRD increased total and f...

  11. The psychological rehabilitation nursing of the patients who have ten- finger complete amputation and survived after replantation

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Objective To explore the mental dynamic change of the ten -finger replanted patients, to give psychological rehabilitation guidance, and to improve the survival of the replantation and function recovery. Methods Take psychological investigation with Scl-90 at different periods after operation, judge the exsisting negative psychological factors, and find the countermeasure of solution. Enable the patients to break away from the negative mentations in short period. Results Through the 1 -week, 8 -week and 16 -week Scl - 90 measurements after operation, we found that all the items' score of the three times measurement was higher thanthe usual modellp <0. 05), and fiufuated up and down with mental charadedstics of different phases. The assessment of the replantation of the severed finger was good. Conclusion The psychological state of the patient would affect the survivial and function recovery of the replantation of severed finger directly. 5o the psychological rehabilitation nursing should be performed throughout the disease.

  12. [Partial replantation following proximal limb injury].

    Science.gov (United States)

    Dubert, T; Malikov, S A; Dinh, A; Kupatadze, D D; Oberlin, C; Alnot, J Y; Nabokov, B B

    2000-11-01

    Proximal replantation is a technically feasible but life-threatening procedure. Indications must be restricted to patients in good condition with a good functional prognosis. The goal of replantation must be focused not only on reimplanting the amputated limb but also on achieving a good functional outcome. For the lower limb, simple terminalization remains the best choice in many cases. When a proximal amputation is not suitable for replantation, the main aim of the surgical procedure must be to reconstruct a stump long enough to permit fitting a prosthesis preserving the function of the adjacent joint. If the proximal stump beyond the last joint is very short, it may be possible to restore some length by partial replantation of spared tissues from the amputated part. We present here the results we obtained following this policy. This series included 16 cases of partial replantations, 14 involving the lower limb and 2 the upper limb. All were osteocutaneous microsurgical transfers. For the lower limb, all transfers recovered protective sensitivity following tibial nerve repair. The functional calcaeoplantar unit was used in 13 cases. The transfer of this specialized weight bearing tissue provided a stable distal surface making higher support unnecessary. In one case, we raised a 13-cm vascularized tibial segment covered with foot skin for additional length. For the upper limb, the osteocutaneous transfer, based on the radial artery, was not reinnervated, but this lack of sensitivity did not impair prosthesis fitting. One vascular failure was finally amputated. This was the only unsuccessful result. For all other patients, the surgical procedure facilitated prosthesis fitting and preserved the proximal joint function despite an initially very proximal amputation. The advantages of partial replantation are obvious compared with simple terminalization or secondary reconstruction. There is no secondary donor site and, because there is no major muscle mass in the

  13. Digital replantation teaching model in rats.

    Science.gov (United States)

    Ad-El, D D; Harper, A; Hoffman, L A

    2000-01-01

    Replant surgery is a complex procedure that requires advanced microsurgical skills and is usually performed as an emergency operation, lasting many hours. For these reasons, teaching replantation is difficult. Although teaching models exist, they are often too general or complicated for routine use and do not simulate the stages and the pitfalls of human replant surgery. We have designed a model that is simple and imitates human replant surgery. After reviewing the rat anatomy, students dissect and replant a rat hind limb that has been sharply amputated by the instructor. They follow the same principles of "real" surgery like debridement, minimizing ischemia time, and stable fixation before anatomosis of vessels. After marking the structures, bony fixation followed by vessel and nerve anastomosis are performed. Muscle is reattached to the skin and limb vascularity evaluated. After we designed this model, plastic surgery residents performed the technique on 10 rats. An 80% limb viability rate was achieved. This model is simple to perform, simulates all the relevant structures and pitfalls of human surgery, and the rats are relatively cheap and can be used for other parallel projects.

  14. The replanting campaign has begun

    CERN Multimedia

    GS-SEM Group - General Infrastructure and Services Department

    2010-01-01

    The poplars on the border of CERN's Prévessin site were felled, according to plan, on Friday, 26 February. The work was essential as the trees were showing signs of serious ageing problems (broken and dead branches, weakened trunks and root systems, etc.) and needed to be felled to ensure the safety of drivers on the D35 The trees that have been cut will be transformed into renewable energy wood chips and used to heat local schools and crèches. They will be replaced by a hedge of hornbeams, a native fast-growing tree, which will be planted in the spring.     The felling operation was entrusted to the French national forestry authorities, with the support of the Bellegarde-Pays de Gex Agence Routière et Technique. It marks the start of a vast poplar-felling and replanting campaign, which will be extended to CERN's Meyrin site.  The work is part of CERN's general renovation and site planning scheme for the future.    

  15. Timing of pulp extirpation for replanted avulsed teeth.

    LENUS (Irish Health Repository)

    Stewart, Chris

    2009-01-01

    A search was performed (April 2004) across four databases, namely Ovid Medline, Cochrane Library, PubMed and Web of Science, relevant to the proposed PICO ( Patient or problem, Intervention, Comparison, Outcome) question: (P) for a replanted avulsed permanent tooth, (I) is early pulp extirpation within 10-14 days of replantation, (C) compared with delayed pulp extirpation, (O) associated an increased likelihood of successful periodontal healing after tooth replantation. Only articles published in the English language were considered.

  16. Nonsurgical factors of digital replantation and survival rate A metaanalysis

    Directory of Open Access Journals (Sweden)

    Huawei Yu

    2015-01-01

    Full Text Available The aim of this metaanalysis was to evaluate the association between nonsurgical factors and survival rate of digital replantation. A computer search of MEDLINE, OVID, EMBASE and CNKI databases was conducted to identify literatures for digital replantation, with the keywords of "digit," "finger" and "replantation" from their inception to June 10, 2014. Based on the inclusion and exclusion criteria, data were extracted independently by two authors using piloted forms. Review Manager 5.2 software was used for data analysis. The effect of some nonsurgical factors (gender, age, amputated finger, injury mechanisms, ischemia time and the way of preservation on the survival rate of digital replantation was assessed. The metaanalysis result suggested that gender and ischemia time had no significant influence on the survival rate of amputation replantation. However, the survival rate of digital replantation of adults was significantly higher than that of children. The guillotine injury of a finger was easier to replant successfully than the crush and avulsion. The little finger was more difficult for replantation than thumb. Survival rate of fingers stored in low temperature was higher than that in common temperature. The present metaanalysis suggested that age, injury mechanism, amputated finger and the way of preservation were significantly associated with the survival rate of digital replantation.

  17. Endodontic\\\\\\'s view of replantation

    OpenAIRE

    A. Vahid

    1992-01-01

    Replantation means replacement of an avulsed tooth. The most important issue is preserving periodontal health during the process. Therefore, root irrigation or drying should be avoided and tooth should be replaced at soonest time possible. Dental socket should be irrigated by warm normal saline without any curettage. Then, it should be splinted by considering function. After 2 weeks, endodontic therapy should be commenced in order to ameliorating periodontium condition and c...

  18. Coordinated effects of root autotoxic substances and Fusarium oxysporum Schl. f. sp. fragariae on the growth and replant disease of strawberry

    Institute of Scientific and Technical Information of China (English)

    Xusheng ZHAO; Wenchao ZHEN; Yongzhi QI; Xuejing LIU; Baozhong YIN

    2009-01-01

    Effects of hydroxybenzoic acid, an important autotoxic substance in roots, on plant growth, photosynth-esis and Fusarium oxysporum occurrence in succession cropping of strawberry were evaluated in this paper. It was found that plant growth was negatively regulated by hydroxybcnzoic acid or inoculation with E oxysporum. Compared with these single factor treatments, the combination of the hydroxybenzoic acid treatment and E oxysporum inoculation caused more severe inhibition in plant growth, greatly enhanced the occurrence of disease symptoms, and significantly decreased the chlorophyll content, net photosynthetic rate, transpiration rate, stomatal conductance and intercellular CO2 concentration. In the meantime, the chlorophyll fluorescence parameters in strawberry were also significantly affected. After the application of hydroxybenzoic acid, the original chlor-ophyll fluorescence rapidly increased, resulting in a combined corresponding decrease in the maximum chlorophyll fluorescence and the chlorophyll fluorescence transformation efficiency. The effects of hydroxybenzoic acid treatment on the above chlorophyll fluorescence parameters from inoculation were delayed. Similarly, the coordination of hydroxybenzoic acid and E oxysporum showed an elevated negative effect on the degree of inhibition of leaf photosynthesis more than the single factor treatments.

  19. Fingertip replantation: Technical considerations and outcome analysis of 24 consecutive fingertip replantations

    Directory of Open Access Journals (Sweden)

    H Venkatramani

    2011-01-01

    Full Text Available Fingertip amputations are one of the most common injuries faced in an emergency department. Finger tip replantation though technically possible, are not regularly done due to the presumed complexity of the procedure and doubts about the outcome. This article deals with our experience of 24 fingertip replantations in 24 patients done over a period of 8 years since the year 2000. Twenty-one fingertips survived. The most common affected digit in the series was thumb followed by index, middle, and ring. The overall success rate was 87%. Both arterial and venous repair were done in all cases. Replantation was not done if no suitable vein was found for anastomosis. Nine patients did not have nerve repair. Seven of them survived and all of them had satisfactory sensation when examined after 1 year. No patient suffered from cold intolerance. All patients were satisfied with the functional outcome and aesthetic appearance. This article highlights the technical considerations and the outcome of these fingertip replants.

  20. Partial root zone drying (PRD) sustains yield of potatoes (Solanum tuberosum L.) at reduced water supply

    DEFF Research Database (Denmark)

    Shahnazari, Ali; Andersen, Mathias Neumann; Liu, Fulai

    2008-01-01

    Partial root zone drying (PRD) is a new water-saving irrigation strategy being tested in many crop species. Until now it has not been investigated in potatoes (Solanum tuberosum L.). A field experiment on sandy soil in Denmark was conducted under a mobile rainout shelter to study effects of two...... irrigation. The reasons for a better tuber size distribution caused by PRD, however, remain elusive. For optimizing PRD irrigation, the crop physiological reactions to shifting intervals and level of irrigation reduction should be further studied at different growth stages....

  1. Partial root zone drying (PRD) sustains yield of potatoes (Solanum tuberosum L.) at reduced water supply

    DEFF Research Database (Denmark)

    Shahnazari, Ali; Andersen, Mathias Neumann; Liu, Fulai

    2008-01-01

    Partial root zone drying (PRD) is a new water-saving irrigation strategy being tested in many crop species. Until now it has not been investigated in potatoes (Solanum tuberosum L.). A field experiment on sandy soil in Denmark was conducted under a mobile rainout shelter to study effects of two...... subsurface drip irrigation treatments ((1) Full Irrigation (FI) receiving 100% of evaporative demand; and (2) PRD receiving 70% water of FI) on potato yield, tuber size, leaf water relations and irrigation water use efficiency (IWUE). The PRD treatment was started just after the end of tuber initiation...

  2. Fingertip replantations: clinical evaluation of 135 digits.

    Science.gov (United States)

    Kim, W K; Lim, J H; Han, S K

    1996-09-01

    From July 1985 to February 1993, 135 digits in 119 patients with complete amputations at or distal to the distal interphalangeal joint (zone I for amputations distal to the nail base of zone II for amputations between the distal interphalangeal joint and the nail base) were replanted using a microsurgical technique at Korea University Guro Hospital. Because of the high social value placed on body form and function, the indication for replantation was extended to cases with severe soft-tissue injuries and attempted replantation as a routine procedure in nearly all distal amputation cases. The overall survival rate was 78 percent, with the survival rate for zone I being 70 percent and that for zone II reaching 86 percent. Even in cases with severe soft-tissue injury, the survival rate was high, with viability in avulsion injuries and crush injuries reaching 75 percent each. The most common type of vascular repair in zone I cases was revascularization of one artery only and no vein repair (87 percent). Of these cases, interpositional vein grafts were used in 65 percent. In zone II cases, the most common combination repair was one artery and one vein anastomosis (70 percent), with interpositional vein grafts for arterial anastomosis in 49 percent; most of the venous repair was feasible by the direct method (78 percent). The follow-up period ranged from 1 month to 5 years with a mean of 14.8 months; 52 patients were followed-up for more than 6 months. In 52 long-term follow-up patients, the average two-point discrimination was 8 mm. Patient satisfaction, aesthetically and functionally, was high (91 percent).

  3. Intentional extraction and replantation: the last resort.

    Science.gov (United States)

    Abdurahiman, V T; Jolly, Sanju John; Khader, M Abdul

    2013-01-01

    The importance of the first molar in the development of occlusion is well-known. The difficulties when first molar is not there during the eruption of the second molar and the premolar don't have to be explained much. The construction of a space maintainer in the area of missing first molar is difficult when seven and five are not erupted. The article highlights a case where a grossly decayed first molar with repeated endodontic failures was treated by intentional extraction and replantation as a last resort. A follow-up along with indications and considerations are documented.

  4. Intentional extraction and replantation: The last resort

    Directory of Open Access Journals (Sweden)

    V T Abdurahiman

    2013-01-01

    Full Text Available The importance of the first molar in the development of occlusion is well-known. The difficulties when first molar is not there during the eruption of the second molar and the premolar don′t have to be explained much. The construction of a space maintainer in the area of missing first molar is difficult when seven and five are not erupted. The article highlights a case where a grossly decayed first molar with repeated endodontic failures was treated by intentional extraction and replantation as a last resort. A follow-up along with indications and considerations are documented.

  5. Reverse Distal Transverse Palmar Arch in Distal Digital Replantation.

    Science.gov (United States)

    Wei, Ching-Yueh; Orozco, Oscar; Vinagre, Gustavo; Shafarenko, Mark

    2017-07-22

    Refinements in microsurgery have made distal finger replantation an established technique with high success rates and good functional and aesthetic outcomes. However, it still represents a technically demanding procedure due to the small vessel caliber and frequent lack of vessel length, requiring the use of interpositional venous grafts in some instances. We describe a new technique for anastomosis in fingertip replantation, whereby the need for venous grafts is eliminated. Applying the reverse distal transverse palmar arch technique, 11 cases of distal digital replantation were performed between January 2011 and July 2016. The described procedure was used for arterial anastomosis in 10 cases and arteriovenous shunting for venous drainage in 1 case. A retrospective case review was conducted. The technical description and clinical outcome evaluations are presented. Ten of the 11 replanted digits survived, corresponding to an overall success rate of 91%. One replant failed due to venous insufficiency. Blood transfusions were not required for any of the patients. Follow-up (range, 1.5-5 months) revealed near-normal range of motion and good aesthetic results. All of the replanted digits developed protective sensation. The average length of hospital admission was 5 days. All patients were satisfied with the results and were able to return to their previous work. The use of the reverse distal transverse palmar arch is a novel and reliable technique in distal digital replantation when an increase in vessel length is required, allowing for a tension-free arterial repair without the need for vein grafts.

  6. Replantation vs revision amputation in single digit zone II amputations.

    Science.gov (United States)

    El-Diwany, M; Odobescu, A; Bélanger-Douet, M; Berbiche, D; Arsenault, J; Bou-Merhi, J; Harris, P G; Danino, A M

    2015-06-01

    The objective of this study was to compare the functional outcomes of zone II amputations treated with either replantation or revision amputation at our institution to better aid patients in their decision making process regarding these treatment options. We conducted a comparative retrospective study. All cases of single digit amputations received at our replantation center between 2007 and 2011 were screened for single digit zone II injuries. These patients were stratified based on the treatment received: replantation vs revision amputation. Patients were called and invited to participate in the research project. Those who accepted to enter the study were asked to complete the Quick-DASH, the Beck Depression Inventory-short form, and a custom made questionnaire. There were seventeen patients with single digit zone II replantation and fourteen patients with similar injuries who underwent revision amputation and agreed to take part in the study. Our data revealed that the duration of sick leave, occupation after injury, professional and social reintegration, discontinued activities, and self-confidence were not statistically different between the two groups. The average hospital stay and the follow-up period of replanted individuals were longer. The replantation group did not have higher levels of pain or cold intolerance, and the global functional and esthetic satisfaction levels were similar between the two groups. Also, Beck Depression Inventory and Quick-DASH scores were not statistically different. Yet, significantly more patients in the replantation group would opt to repeat the replantation than revised patients would opt for revision amputation. From a functional viewpoint, our study suggests that revision amputation is not superior to replantation in zone II single digit amputations. This is valuable information that should be given to patients when deciding on the treatment process and to insure a proper informed consent. Copyright © 2015. Published by

  7. DENTAL CARE FOR CHILDREN AFTER REPLANTATION OF AVULSED PERMANENT INCISORS

    Directory of Open Access Journals (Sweden)

    Rossitza Kabaktchieva

    2016-12-01

    Full Text Available The diagnosis avulsion of permanent tooth/teeth is an emergency situation which has special requirements in respect of proper storage of the avulsed tooth, the need of urgent medical/dental care, time past till replantation and splinting, the need for endodontic treatment and long term follow up period. Those clinical actions depend on three groups: parents/people who are with the child in the moment when trauma happens and give the first aid; dental specialist- surgeon who replants the tooth/teeth; dental specialist- endodontist who takes care of the endodontic treatment and the long period after treatment for follow up and observation of the replanted teeth. The aim of the paper is to present the dental postoperative care in a couple of cases of children with trauma and replanted avulsed permanent incisors. Material and methods: We present four clinical cases of children who get 6 permanent upper incisors replanted. Replantation is made by the oral surgeon. Treatment and observation after replantation are made by dental specialists of pediatric dentistry and conservative dentistry. All 4 cases get 3 years follow up period. Results: After replantation of 2 central incisors with complete root development (first clinical case the left one has developed a resorption of the root but the right one is in a stable condition. Replantation of 3 teeth with incomplete root development (second and third clinical cases where the patients refer to specialized surgical care less than 60 minutes after injury and store the teeth in different ways lead to different clinical results. In the case of avulsed upper right incisor (second case, it is stored in milk and we observe revascularization followed by partial root canal obliteration. The tooth is scheduled for endodontic treatment. In the case of upper central incisors, both kept dry till replantation in the alveolus filled up with substitute bone, we observe fast root resorption which going to lead to early

  8. Cross-over limb replantation: a case report.

    Science.gov (United States)

    Holmes, W J M; Williams, A; Everitt, K J M; Kay, S P J; Bourke, G

    2013-10-01

    Following traumatic bilateral arm amputation in a 46-year-old woman, orthotopic replantation was not possible. The patient underwent replantation of the left forearm to the right proximal forearm. At two years she has a sensate hand, with good recovery of her long flexors of the hand and wrist extensors. DASH score is 93.9 and Chen's score is III (medium). We demonstrate a high level of function compared to the contralateral prosthetic limb. There have only been four similar cases described. Although a rare circumstance, a cross-limb replant can provide a level of function and independence superior to a simple prosthesis. Cross-limb transfer should be considered in situations where bilateral arm amputation is present and neither can be orthotopically replanted.

  9. Replantation of multiple digits and hand amputations: four case reports

    OpenAIRE

    Salah, Mohammed Murshid; Khalid, Khalid N

    2008-01-01

    This study reports four cases of hand avulsion at the proximal wrist level and multiple digits amputation were received in plastic and hand surgery unit during the year 2007–2008. All patients were male labors between 22–30 years old, and the amputation due to machine injuries. Successful replantation were achieved, after a period of follow up with occupational therapy all patients regain good functional and cosmetic results. This study proves the strong indication of replantation of multiple...

  10. Performance of PRD Welled Surfaces in T Shape Noise Barriers for Controlling Environmental Noise

    Directory of Open Access Journals (Sweden)

    S Momen Bellah

    2010-07-01

    Full Text Available "n "n "nBackgrounds and Objectives: There is a considerable notice in the use of noise barriers in recent years. Noise barriers as a control noise solution can increase the insertion loss to protect receivers. This paper presents the results of an investigation about the acoustic efficiency of primitive root sequence diffuser (PRD on environmental single T-shape barrier."nMaterials and Methods: A 2D boundary element method (BEM is used to predict the insertion loss of the tested barriers. The results of rigid and with quadratic residue diffuser (QRD coverage are also predicted for comparison."nResults: It is found that decreasing the design frequency of PRD shifts the frequency effects towards lower frequencies, and therefore the overall A-weighted insertion loss is improved. It is also found that using wire mesh with reasonably efficient resistivity on the top surface of PRD improves the efficiency of the reactive barriers; however utilizing wire meshes with flow resistivity higher than specific acoustic impedance of air on the PRD top of a diffuser barrier significantly reduces the performance of the barrier within the frequency bandwidth of the diffuser. The performance of PRD covered T-shape barrier at 200 Hz was found to be higher than that of its equivalent QRD barriers in both the far field and areas close to the ground. The amount of improvement compared made by PRD barrier compared with its equivalent rigid barrier at far field is about 2 to 3 dB, while this improvement relative to barrier model .QR4. can reach up to 4- 6 dB."nConclusion: Employing PRD on the top surface of T-shape barrier is found to improve the performance of barriers compared with using rigid and QRD coverage at the examined receiver locations.

  11. [Experiment and clinical application of squeezing technique in venous crisis after replantation of finger].

    Science.gov (United States)

    Chen, H; Zhu, Z; Xu, G

    1997-11-01

    In search of a new method for treating venous crisis after replantation of the finger, the effect of instantaneous, quick and forceful squeezing on the belly of replanted finger (the so-called SQUEEZINGG TECHNIQUE) was studied. In the animal experiment, 20 SD rats were used. The femoral veins and arteries were separated in order to measure the venous pressure. The result showed that the venous pressure was (8.33 +/- 1.29) x 10(-2) kPa in normal condition, (20.61 +/- 2.34) x 10(-2) kPa in the condition simulating venous crisis and (73.9 +/- 5.74) x 10(-2) kPa on carrying out the squeezing technique. The second part of the experiment was performed on ten human fingers which were amputated because of trauma or other diseases. One of the arteriae digitales palmares propriae and two of its accompanied veins were disected, and all other blood vessels were ligated. The artery was irrigated with normal saline at a pressure of 12 kPa. When both veins were left open, the venous pressure was (1.32 +/- 0.17) kPa; (4.29 +/- 0.49) kPa, when both were ligated; and (16.88 +/- 5.25) kPa when the squeezing technique was applied at the time venous crisis developed. From May 1991 to May 1996, this method was used for 43 times in 25 cases (35 fingers) with venous crisis after replantation. It was successful for 39 times in 21 cases (30 fingers). It was very important that the performer should use the thumb and the index finger to squeeze just the belly of the involved finger, and that every squeeze should be forceful, quick and instantaneous. It was suggested that if this method was properly performed it could improve the survival rate of replanted fingers. The mechanism of squeezing technique in the treatment of venous crisis following replantation of finger was proposed.

  12. Replantation versus prosthetic fitting in traumatic arm amputations : A systematic review

    NARCIS (Netherlands)

    Otto, Iris A.; Kon, Moshe; Schuurman, AH; Van Minnen, L. Paul

    2015-01-01

    Background: Traumatic arm amputations can be treated with replantation or surgical formalization of the stump with or without subsequent prosthetic fitting. In the literature, many authors suggest the superiority of replantation. This systematic review compared available literature to analyze whethe

  13. Advantages of using volar vein repair in finger replantations.

    Science.gov (United States)

    Mersa, Berkan; Kabakas, Fatih; Pürisa, Hüsrev; Özçelik, Ismail Bülent; Yeşiloğlu, Nebil; Sezer, Ilker; Tunçer, Serdar

    2014-01-01

    Providing adequate venous outflow is essential in finger replantation surgeries. For a successful result, the quality and quantity of venous repairs should be adequate to drain arterial inflow. The digital dorsal venous plexus is a reliable source of material for venous repairs. Classically, volar digital veins have been used only when no other alternative was available. However, repairing volar veins to augment venous outflow has a number of technical advantages and gives a greater chance of survival. Increasing the repaired vein:artery ratio also increases the success of replantation. The volar skin, covering the volar vein, is less likely to be avulsed during injury and is also less likely to turn necrotic, than dorsal skin, after the replantation surgery. Primary repair of dorsal veins can be difficult due to tightness ensuing from arthrodesis of the underlying joint in flexion. In multiple finger replantations, repairing the volar veins after arterial repair and continuing to do so for each finger in the same way without changing the position of the hand and surgeon save time. In amputations with tissue loss, the size discrepancy is less for volar veins than for dorsal veins. We present the results of 366 finger replantations after volar vein repairs.

  14. Lower limb replantations: indications and a new scoring system.

    Science.gov (United States)

    Battiston, Bruno; Tos, Pierluigi; Pontini, Italo; Ferrero, Sebastiano

    2002-01-01

    The need for reconstruction of lower limb amputations is increasing, due to high-energy trauma in road accidents and work-related injuries. The indication for lower limb replantation is still controversial. Compared with upper limb replantations, indications are more select due to the frequent complications in lower limb salvage procedures, such as severe general complications or local complications such as necrosis, infections, nonunions, the need for secondary lengthening, or other reconstructive procedures. The satisfactory results given by artificial prosthesis, such as quicker recovery time and fewer secondary procedures, also contribute to the higher degree of selection for lower limb replantation candidates. Since 1993, we have replanted 14 amputations of the lower limb in 12 patients, including 2 bilateral cases. Although survival of the replanted segment was obtained in all patients, 5 cases were subsequently amputated for severe secondary complications. Of the remaining 9 cases, evaluated by means of Chen criteria, 7 had good results (3 Chen I and 4 Chen II), 1 sufficient (Chen III), and 1 poor (Chen IV). The best results were obtained in young patients. Our experience led us to examine the necessity for careful, objective patient selection. We developed a score evaluation system by modifying the international classifying method for severe limb traumas (mangled extremity severity score, or MESS system). This relatively simple system, based on the retrospective study of our cases, considers several parameters (patient's age, general conditions, level and type of lesion, time of injury, and associated lesions), giving each one a score. The total score gives the indication for replantation, predicts the functional outcome, and facilitates decision-making.

  15. Analysis of Bone Fixation Methods in Digital Replantation

    Science.gov (United States)

    Lee, Seung Woo; Kim, Jin Soo; Roh, Si Young; Lee, Kyung Jin

    2017-01-01

    Background Adequate fixation of replanted digits is essential not only for short-term healing but for long-term function. Various bony fixation methods using Kirschner (K-) and intraosseous wire are available in replantation. We examined clinical and radiographic outcomes of fixation methods on bone union after digital replantation. Methods A single institutional retrospective review identified 992 patients who had undergone 1,247 successful replantations between July 2009 and September 2015. Exclusion criteria included amputations of the distal phalanx, comminuted fractures, and intra-articular fractures. Patients were classified according to 5 categories of fixation methods: single K-wire, double longitudinal K-wires, cross K-wires, wire with, and wire without K-wire support. Bone union was evaluated by 5-month postoperative X-ray and fixation outcomes were compared across the 5 groups. Results The exclusion criteria were applied, and 88 patients with 103 replanted digits remained for analysis. Single K-wire fixation was used in 40 digits, double longitudinal K-wires in 30, and cross fixation in 14. Wire with and without K-wire support was required in 15 and 4 digits. Nonunion was observed in 32 digits (31.1%), of which 13 required additional operations such as bone graft or corrective osteotomy. The highest percent of nonunion was observed after cross fixation (35.7%) and the lowest after wire alone (25.0%). Conclusions In this study, contrary to general knowledge, we found that single K-wire fixation was not associated with poorer outcomes. Successful bone union outcomes may be achieved by careful selection of bone fixation methods. This study provides useful information for planning bone fixation in digital replantation. PMID:28194348

  16. Penile Replantation After Five Hours of Warm Ischemia

    Directory of Open Access Journals (Sweden)

    Fernando N. Facio Jr.

    2015-05-01

    Full Text Available Although a rare occurrence, this event may occur as a result of self-mutilation among individuals with psychiatric disturbances or due to work-related accidents, iatrogenic injuries or the actions of individuals motivated by jealously, rage and feelings of betrayal. In western societies, most penile amputations are the result of self-aggression during a psychotic episode, the treatment of victims involves resuscitation, stabilization and immediate psychiatric support. The amputated tissue must be preserved under hypothermic conditions. Micro-surgery is currently the most widely employed method for penile replantation. This paper describes a successful case of penile replantation following 5 hours of warm ischemia.

  17. PRD3000: A novel Personnel Radiation Detector with Radiation Exposure Monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Fallu-Labruyere, A.; Micou, C.; Schulcz, F.; Fellinger, J. [Mirion Technologies - MGPI SA (France)

    2015-07-01

    PRD3000{sup TM} is a novel Personal Radiation Detector (PRD) with personnel radiation dose exposure monitoring. It is intended for First Responders, Law Enforcement, Customs Inspectors protecting critical infrastructures for detecting unexpected radioactive sources, who also need real time Hp(10) dose equivalent information. Traditional PRD devices use scintillator materials instrumented through either a photomultiplier tube or a photodiode photodetector. While the former is bulky and sensitive to magnetic fields, the latter has to compromise radiation sensitivity and energy threshold given its current noise per unit of photo-detection surface. Recently, solid state photodetectors (SiPM), based on arrays of Geiger operated diodes, have emerged as a scalable digital photodetector for photon counting. Their strong breakdown voltage temperature dependence (on the order of tens of milli-volts per K) has however limited their use for portable instruments where strong temperature gradients can be experienced, and limited power is available to temperature stabilize. The PRD3000 is based on the industry standard DMC3000 active dosimeter that complies with IEC 61526 Ed. 3 and ANSI 42.20 for direct reading personal dose equivalent meters and active personnel radiation monitors. An extension module is based on a CsI(Tl) scintillator readout by a temperature compensated SiPM. Preliminary nuclear tests combined with a measured continuous operation in excess of 240 hours from a single AAA battery cell indicate that the PRD3000 complies with the IEC 62401 Ed.2 and ANSI 42.32 without sacrificing battery life time. We present a summary of the device test results, starting with performance stability over a temperature range of - 20 deg. C to 50 deg. C, false alarm rates and dynamic response time. (authors)

  18. Single centre experience of the upper limb replantation and revascularisation.

    Science.gov (United States)

    Visnjic, Milan M; Kovacevic, Predrag T; Paunkovic, Ljiljana M; Milenkovic, Sasa S

    2004-01-01

    Replantation is defined as reattachment of the amputated limb using the neurovascular and musculoskeletal structures in order to obtain the recovery of the limb. Fortunately, injuries causing limb amputation are rare. Adequate treatment within the optimal time scale can provide successful rehabilitation of the shape and function of the replanted part. We report the experience of our Clinical Centre (regional replantation centre) in the replantation of five forearms/hands and revascularisation of six hands between 1997 and 2001. The most frequent site of injury was the distal part of the forearm, while the major cause of injuries was a wood processing machine. The surgical procedures were performed under general anaesthesia within 2-6 hours after injury. Vascular anastomoses, nerve repair and muscle repair were performed following the external bone fixation. All patients were given anticoagulation treatment postoperatively. Thrombosis in the anastomotic site developed as an early complication in two patients who underwent thrombectomy; one of these patients developed gangrene and underwent amputation. Late postoperative results were good in 10 patients. One patient developed acral epidermolysis. Postoperative results after revascularisation were good in all patients.

  19. Delayed, bilateral, non-microvascular ear replantation after violent amputation.

    Science.gov (United States)

    García-Murray, E; Adán-Rivas, O; Salcido-Calzadilla, H

    2009-06-01

    Amputation of any body part is undoubtedly a traumatic experience leaving a terrible deformity, especially when the part or parts involved are visible and constitute an essential component of someone's facial whole. Bilateral ear amputation and successful subsequent replantation has been reported historically, but not in the modern surgical literature. We report the case of a 27-year-old female who was abducted and suffered a bilateral ear amputation at the hands of one of her captors to speed delivery of ransom money; the severed parts were sent to the parents approximately 2 hours after the amputation had taken place, and the girl was released some 48 hours after the ears were delivered. Microvascular replantation was attempted immediately after admission to the hospital some 2 hours after her release, but failed, and so a non-microvascular replantation was performed and was successful, after approximately 54 hours of ischaemia time. We consider this the first report of a complete bilateral, delayed, non-microvascular, successful ear replantation in a human being in the modern literature.

  20. Successful Replantation of Amputated Penile Shaft following Industrial Injury

    Directory of Open Access Journals (Sweden)

    M Salehipour

    2010-09-01

    Full Text Available Penile amputation is an uncommon urological emergency. Although rare, traumatic amputation of penis is a challenging injury to treat. However, modern microsurgical reconstruction techniques have improved success rate of penile replantation and become the procedure of choice for managing these patients. Herein, we report on a case of penile amputation following an industrial accident.

  1. Reorganization of human motor cortex after hand replantation.

    Science.gov (United States)

    Röricht, S; Machetanz, J; Irlbacher, K; Niehaus, L; Biemer, E; Meyer, B U

    2001-08-01

    In 10 patients, reorganizational changes of the motor cortex contralateral to a replanted hand (MCreplant) were studied one to 14 years after complete traumatic amputation and consecutive successful replantation of the hand. The organizational state of MCreplant was assessed for the deafferentated and peripherally deefferentated hand-associated motor cortex and the adjacent motor representation of the proximal arm. For this, response maps were established for the first dorsal interosseus and biceps brachii muscle using focal transcranial magnetic stimulation (TMS) on a skull surface grid. Characteristics of the maps were center of gravity (COG), number of effective stimulation sites, amplitude sum, and amplitudes and response threshold at the optimal stimulation point. The COG is defined by the spatial distribution of response amplitudes on the map and lies over the cortex region with the most excitable corticospinal neurones supplying the recorded muscle. The COG of the biceps map in MCreplant was shifted laterally by 9.8 +/- 3.6 mm (range 5.0-15.7 mm). The extension of the biceps map in MCreplant was increased and the responses were enlarged and had lowered thresholds. For the muscles of the replanted hand, the pattern of reorganization was different: Response amplitudes were enlarged but thresholds, COG, and area of the cortical response map were normal. The different reorganizational phenomena observed for the motor cortical areas supplying the replanted hand and the biceps brachii of the same arm may be influenced by a different extent of deafferentation and by their different role in hand motor control.

  2. What to do with non-replanted hands?

    NARCIS (Netherlands)

    Willian Stenekes, Martin; Nicolai, Jean-Philippe A.

    2009-01-01

    We describe a method for the preparation of amputated limbs to obtain a specimen for anatomical study of the arteries and the skeleton. The procedure is particularly applicable to hands, and prevents the destruction of a perfect hand that cannot be replanted.

  3. High-Grade Leiomyosarcoma Arising in a Previously Replanted Limb

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    Tiffany J. Pan

    2015-01-01

    Full Text Available Sarcoma development has been associated with genetics, irradiation, viral infections, and immunodeficiency. Reports of sarcomas arising in the setting of prior trauma, as in burn scars or fracture sites, are rare. We report a case of a leiomyosarcoma arising in an arm that had previously been replanted at the level of the elbow joint following traumatic amputation when the patient was eight years old. He presented twenty-four years later with a 10.8 cm mass in the replanted arm located on the volar forearm. The tumor was completely resected and pathology examination showed a high-grade, subfascial spindle cell sarcoma diagnosed as a grade 3 leiomyosarcoma with stage pT2bNxMx. The patient underwent treatment with brachytherapy, reconstruction with a free flap, and subsequently chemotherapy. To the best of our knowledge, this is the first case report of leiomyosarcoma developing in a replanted extremity. Development of leiomyosarcoma in this case could be related to revascularization, scar formation, or chronic injury after replantation. The patient remains healthy without signs of recurrence at three-year follow-up.

  4. Replantation versus Prosthetic Fitting in Traumatic Arm Amputations: A Systematic Review.

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    Iris A Otto

    Full Text Available Traumatic arm amputations can be treated with replantation or surgical formalization of the stump with or without subsequent prosthetic fitting. In the literature, many authors suggest the superiority of replantation. This systematic review compared available literature to analyze whether replantation is functionally and psychologically more profitable than formalization and prosthetic fitting in patients with traumatic arm amputation.Functional outcome and satisfaction levels were recorded of patients with amputation levels below elbow, through elbow, and above elbow.Functional outcomes of 301 replantation patients and 172 prosthesis patients were obtained. In the replantation group, good or excellent functional scores were reported in 39% of above elbow, 55% of through elbow, and 50% of below elbow amputation cases. Nearly 100% of patients were satisfied with the replanted limb. In the prosthesis group, full use of the prosthesis was attained in 48% of above elbow and in 89% of below elbow amputation patients. Here, 29% of patients elected not to use the prosthesis for reasons including pain and functional superfluity. In both replantation patients and prosthesis wearers, a below elbow amputation yielded better functional results than higher amputation levels.Replantation of a traumatically amputated arm leads to good function and higher satisfaction rates than a prosthesis, regardless of the objective functional outcome. Sensation and psychological well-being seem the two major advantages of replantation over a prosthesis. The current review of the available literature shows that in carefully selected cases replantation could be the preferred option of treatment.

  5. Sensory outcome of fingertip replantations without nerve repair.

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    Ozcelik, Ismail Bulent; Tuncer, Serdar; Purisa, Husrev; Sezer, Ilker; Mersa, Berkan; Kabakas, Fatih; Celikdelen, Pinar

    2008-01-01

    The sensory recovery outcomes of fingertip replantations without nerve repair were retrospectively studied. Between 2000 and 2006, 112 fingertip replantations with only arterial repair were carried out in 98 patients. About 76 of the replants survived totally, with a success rate of 67.8%. Evaluation of sensory recovery was possible in 31 patients (38 replantations). Sensory evaluation was made with Semmes-Weinstein, static and dynamic two-point discrimination, and vibration sense tests. Fingertip atrophy, nail deformities, and return to work were also evaluated. According to the Semmes-Weinstein test, 29.0% (11/38) of the fingers had normal sense, 60.5% (23/38) had diminished light touch, 7.9% (3/38) had diminished protective sensation, and 2.6% (1/38) had loss of protective sensation. Mean static and dynamic two-point discriminations were 7.2 mm (3-11 mm), and 4.60 mm (3-6 mm), respectively. Vibratory testing revealed increased vibration in 42.1% of the fingers, decreased vibration in 36.8%, and equal vibration when compared with the non-injured fingers in 21.1%. Atrophy was present in 14 (36.8%) fingers and negatively affected the results. Nail deformities, cold intolerance, return to work, and the effect of sensory education were investigated. Comparison of crush and clean cut injuries did not yield any significant difference in any of the parameters. Patients who received sensory education had significantly better results in sensory testing. The results were classified as excellent, good, and poor based on results of two-point discrimination tests. The outcome was excellent in 18 fingers and good in 20 fingers. Overall, satisfactory sensory recovery was achieved in fingertip replantations without nerve repair.

  6. Regional Integrated Experiments on Air Quality over Pearl River Delta 2004 (PRIDE-PRD2004): Overview

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    Zhang, Y. H.; Hu, M.; Zhong, L. J.; Wiedensohler, A.; Liu, S. C.; Andreae, M. O.; Wang, W.; Fan, S. J.

    The aims of the Program of Regional Integrated Experiments on Air Quality over Pearl River Delta of China 2004 (PRIDE-PRD2004) were to characterize in depth the pollution, and to improve the understanding of the chemical and radiative processes in the atmosphere of Pearl River Delta (PRD) in South-Eastern China. This comprehensive program integrated ground-base in situ measurements, vertical observations (including aircraft) and model simulations. The intensive field campaign was conducted from 4 October to 5 November 2004 at two super-sites: an urban site in Guangzhou city (23.13°N, 113.26°E) and a non-urban site at Xinken (22.61°N, 113.59°E). They were coordinated with concurrent meteorological observations as well as measurements at stations of a regional monitoring network. Quality control and quality assurances, application of closure studies and observation-based modeling were the key elements of the research strategies for the PRIDE-PRD2004 campaign. Knowledge and understanding of the important issues, including 3-D distribution of air pollution, ozone formation process and its control strategies, sources of volatile organic compounds, chemical and physical characteristics and radiative properties of aerosols, and the important role of nitrous acid atmospheric chemistry, have been improved substantially by this study.

  7. Functional outcome of patients undergoing replantation of hand at wrist level-7 year experience

    OpenAIRE

    Ravi Kumar Mahajan; Seema Mittal

    2013-01-01

    Background: Replantation is defined as reattachment of amputated limb using neurovascular and musculoskeletal structures in order to obtain recovery of limb. Re-vascularisation involves all the above steps in case of limb injuries that result in a near total amputation. Aim and Objective : To study the functional outcome of patients undergoing replantation of hand at wrist level. Material and Methods: This is a retrospective study of patients who underwent replantation of total amputation of ...

  8. Crossover replantation as a salvage procedure following bilateral transhumeral upper limb amputation: a case report.

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    Ozçelik, Ismail Bülent; Mersa, Berkan; Kabakaş, Fatih; Saçak, Bülent; Kuvat, Samet Vasfi

    2011-04-01

    Cross-over replantation is a salvage option for cases with bilateral extremity amputations where the wound conditions do not enable an orthotopic replantation. Here, we present a 24-year-old patient who applied to our center with bilateral transhumeral amputations. Due to the wound conditions, a cross-over replantation was performed. 24 months after the initial operation, the patient exhibits good protective sensation at the distal levels and function to some degree, whereas the active range of motion is not as promising as previously expected. In this article, we present this case together with its immediate and long-term outcomes and the consequences of the cross-over replantation.

  9. Cross-arm replantation for traumatic bilateral upper extremity amputations: a case report.

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    Liang, Kailu; Zhong, Gang; Yin, Jiahui; Xiang, Zhou; Cen, Shiqiang; Huang, Fuguo

    2011-02-01

    A 40-year-old woman had her right extremity avulsed at the proximal upper arm level and the wrist and hand of her left extremity irretrievably injured in a traffic accident. The right distal forearm was surgically amputated and replanted onto the stump of the left distal forearm. New strategy for nerve repair was applied and the function recovery of the cross-replanted hand was favorable. We thought that cross-extremity replantation was indicated when the patient suffered from bilateral total or subtotal amputation at different levels and orthotopic replantation was impossible.

  10. Finger Replantation in Sanglah General Hospital: Report of Five Cases and Literature Review

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    Agus Roy Rusly Hariantana Hamid

    2016-11-01

    Full Text Available Background: Replantation is the prime treatment for amputated hands and fingers due to functional and aesthetic advantages. The absolute indications for replantation are amputations of the thumb, multiple fingers, trans metacarpal or hand, and any upper extremity in a child, regardless of the amputation level. A fingertip amputation distal to the insertion of the flexor digitorum superficialis (FDS is also a good indication. Indications have been expanded to include amputation at nail level, and when there is a request from the patient, replantation is attempted even for a single finger amputation regardless of the amputation level. Based on the mechanism of injury, a clean-cut sharp amputation is more likely replanted compare to a crush and avulsion injuries. With a proper management of the amputated finger, replantation can be attempted even after 24 hours. This report was written to provide examples of finger replantation cases and the measures that can be taken in a resource-limited hospital in order to conduct a replantation. Case Series: We reported five out of nine digital replantation cases in Sanglah General Hospital between January and July 2014. Two patients were a six and an eleven years old boys who accidentally cut their finger while playing, the rests were male labors between 20-30 years old whose amputations due to machine injuries. Result: A 100% replant survival was achieved. After a period of follow up with occupational therapy, all patients regain good functional and cosmetic results. 

  11. A surgical approach for replantation of complete digital amputations.

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    Nissenbaum, M

    1980-01-01

    A technique of extending exposure in digital replantation using lateral incisions permits atraumatic exposure of adequate length of digital nerves, arteries, and veins, and excellent exposure for fashioning bone and debridement and repair of tendon. Increase in viability rates, the ability to repair two arteries per digit, the number of veins repaired per digit, and a higher overall arterial patency rate appear to be related to the improved exposure. Operative time was also significantly shorter.

  12. Effect of IRM root end fillings on healing after replantation.

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    Pitt Ford, T R; Andreasen, J O; Dorn, S O; Kariyawasam, S P

    1994-08-01

    The effect of IRM as a root end filling placed in teeth prior to replantation was examined in 21 molar teeth in monkeys. After extraction, root ends were resected, the canals contaminated with oral bacteria, root end cavities prepared, and fillings of IRM or amalgam placed prior to replantation. After 8 wk the jaws were removed and prepared for histological examination. Bacteria were demonstrated in only 9 of 15 teeth filled with IRM; 18 of the roots (60%) were associated with inflammation, which was only moderate or severe around 5 (17%), and extended > 0.1 mm around only 2 roots. In contrast, of the 6 teeth filled with amalgam, all contained bacteria in the root canals and 11 roots were associated with moderate or severe inflammation, which around 8 roots extended > 0.5 mm. The difference in severity of inflammation for the two materials was statistically significant (p IRM in replanted teeth was less severe and less extensive than that to amalgam.

  13. El PRD: Proceso de aprendizaje, trayectoria electoral y organización

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    Esperanza Palma

    2000-01-01

    A pesar de haber elementos contradictorios en el escenario perredista podría plantearse que en términos generales, la intransigencia democrática ha sido prácticamente abandonada durante el gobierno de Zedillo, como resultado de una combinación de factores externos e internos a la organización: la experiencia de las elecciones de 1994, la reforma electoral de 1996, la posición del presidente Zedillo frente al PRD, quien desde el inicio de su gobierno manifestó su intención de integrar a este p...

  14. Crossover replantation after bilateral traumatic lower limb amputations: a case report

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    Fang Jun

    2012-07-01

    Full Text Available Abstract Introduction Replantation of a limb to the contralateral stump after bilateral traumatic amputations is rare. To the best of our knowledge, there are only a few reports of crossover lower limb replantation in the literature. Case presentation We treated a 37-year-old Chinese woman with bilateral lower limb crush injuries sustained in a traffic accident. Her lower limb injuries were at different anatomic levels. We performed emergency bilateral amputations followed by crossover replantation. Five years later, the woman had recovered well, and had perfect movement and stability in her replanted leg. After reviewing the literature, we thought that presentation of our patient’s case might provide useful information for clinicians. Conclusions Crossover replantation should be considered when evaluating a patient with bilateral lower limb injuries, thus allowing the patient to touch the ground and stand using their own foot.

  15. Volatile Organic Compound (VOC measurements in the Pearl River Delta (PRD region, China

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    Chih-chung Chang

    2008-03-01

    Full Text Available We measured levels of ambient volatile organic compounds (VOCs at seven sites in the Pearl River Delta (PRD region of China during the Air Quality Monitoring Campaign spanning 4 October to 3 November 2004. Two of the sites, Guangzhou (GZ and Xinken (XK, were intensive sites at which we collected multiple daily canister samples. The observations reported here provide a look at the VOC distribution, speciation, and photochemical implications in the PRD region. Alkanes constituted the largest percentage (>40% in mixing ratios of the quantified VOCs at six sites; the exception was one major industrial site that was dominated by aromatics (about 52%. Highly elevated VOC levels occurred at GZ during two pollution episodes; however, the chemical composition of VOCs did not exhibit noticeable changes during these episodes. We calculated the OH loss rate to estimate the chemical reactivity of all VOCs. Of the anthropogenic VOCs, alkenes played a predominant role in VOC reactivity at GZ, whereas the contributions of reactive aromatics were more important at XK. Our preliminary analysis of the VOC correlations suggests that the ambient VOCs at GZ came directly from local sources (i.e., automobiles; those at XK were influenced by both local emissions and transportation of air mass from upwind areas.

  16. KARAKTERISASI SIFAT-SIFAT BIOKIMIA EKSTRAK KASAR LIPASE EKSTRASELULER BAKTERI Azospirillum sp.PRD1

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    Santi Nur Handayani

    2011-11-01

    Full Text Available Enzim lipase mempunyai peranan penting dalam katalis berbagai reaksi industri satu diantaranya pembuatan flavor melalui reaksi esterifikasi. Lipase adalah biokatalis yang berperan besar dalam aplikasi bioteknologi, seperti dalam sintesis biopolimer, biodiesel, produksi obat, dan produksi flavor. Peningkatan penggunaan lipase untuk industri mendorong dilakukan penelitian untuk mendapatkan sumber-sumber lipase baru. Sumber lipase yang potensial salah satunya adalah bakteri Azospirillum sp.PRD1 dari isolat lokal Laboratorium Mikrobiologi, Fakultas Biologi Universitas Jenderal Soedirman. Tujuan penelitian adalah untuk mendapatkan ekstrak kasar lipase dan menentukan karakteristik sifat-sifat biokimiawinya. Metode yang digunakan antara lain peremajaan bakteri Azospirillum sp.PRD1, dan produksi inokulum, penentuan waktu produksi optimum dan fase pertumbuhan bakteri, ekstraksi dan produksi ekstrak kasar lipase dan penentuan karakteristik sifat-sifat biokimiawinya. Hasil penelitian diperoleh ekstrak kasar lipase dari inokulum berumur 7 jam dan medium produksi dengan induser minyak zaitun yang diinkubasi selama 3 jam memiliki aktivitas spesifik 7,0547 Unit/mg. Lipase ekstrak kasar optimum pada pH 7, suhu 40 oC dan waktu inkubasi selama 25 menit. Lipase merupakan metaloenzim dengan kofaktor Zn2+ , Mn2+, Hg2+, Ca2+, Co2+ and Mg2+.

  17. The timing of neovascularization in fingertip replantation by external bleeding.

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    Han, Seung-Kyu; Chung, Heung-Soo; Kim, Woo-Kyung

    2002-09-15

    To overcome venous congestion in fingertip replantation with no venous anastomosis, the authors have used a salvage procedure that consists of continuous external bleeding through a stab incision on the paraungual area and dripping a heparinized saline solution at the incision site to maintain external bleeding. Because this method requires continuous bleeding for a certain period of time, it may be a great burden on the patient; therefore, it is most important to minimize the duration of bleeding. Many authors have studied the timing of the new venous channel formation of the flap. However, to our knowledge, a study on fingertip replantations has not yet been performed. From June of 1985 to November of 1999, the authors performed fingertip replantations on 144 fingers of 137 patients using our salvage procedure at Korea University Guro Hospital. Among the 144 fingers, 101 fingers of 96 patients were successfully transplanted, including those with partial necrosis. The authors reviewed the medical records of these 101 fingers retrospectively; they compared and analyzed the necessary duration of external bleeding according to sex, age, level of injury, cause of amputation, and the type of injury. The average period of the salvage procedure was 7.6 days. Regarding age, the shortest period (5.5 days) was required for patients younger than 10 years. On the basis of the types of injuries, the duration of bleeding was shortest for the guillotine injury group (5.9 days) compared with crush (8.2 days) or avulsion (8.0 days) injuries. Sex and level of injury did not make much difference in the duration of the procedure.

  18. Treatment of Superior Lobe Central Lung Cancer with Lung Replantation

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    Yulun YANG

    2010-11-01

    Full Text Available Background and objective Patients suffering from lung cancer often have poor quality of life after pneumonectomy. It has clinical significances to preserve maximum lobes of the “healthy” lung. The aim of this study is to report the applications of lung replantation in treatment of superior lobe central lung cancer. Methods Three lung cancer cases were included and analysed. The bronchus and margin of lower lung lobe were encroached by cancer. Pulmonary artery was invaded and surrounded by metastatic lymph node. Complete pneumonectomy, antegrade perfusion and retroperfusion with low-potassium dextran (LPD solution in vitro were performed. The retainable lower pulmonary lobe was selected from the isolated lung and superior pulmonary vein was replaced with inferior pulmonary veins. The bronchus and pulmonary artery were inosculated by turns. Results The operative cumulative time ranged from 220 min to 250 min. The isolated time of lobus inferior pulmonary ranged from 120 min to 150 min. The chest tube was pulled out after chest X-ray confirmed the reimplant lung full re-expansion. The patients were followed up for 4 months to 8 months and accomplished adjuvant chemotherapy for 3 or 4 periodicities. The patients had a sound quality of life. Conclusion Lung replantation removing the extensive tumor tissue and retaining the maximum pulmonary normal tissue is an useful method for treatment of lung cancer.

  19. Apical Revascularization after Delayed Tooth Replantation: An Unusual Case

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    Marília Pacífico Lucisano

    2016-01-01

    Full Text Available The aim of this paper is to present the clinical and radiological outcome of the treatment involving a delayed tooth replantation after an avulsed immature permanent incisor, with a follow-up of 1 year and 6 months. An 8-year-old boy was referred after dental trauma that occurred on the previous day. The permanent maxillary right central incisor (tooth 11 had been avulsed. The tooth was hand-held during endodontic therapy and an intracanal medication application with calcium hydroxide-based paste was performed. An apical plug with mineral trioxide aggregate (MTA was introduced into the apical portion of the canal. When the avulsed tooth was replanted with digital pressure, a blood clot had formed within the socket, which moved the MTA apical plug about 2 mm inside of the root canal. These procedures developed apical revascularization, which promoted a successful endodontic outcome, evidenced by apical closure, slight increase in root length, and absence of signs of external root resorption, during a follow-up of 1 year and 6 months.

  20. Apical Revascularization after Delayed Tooth Replantation: An Unusual Case

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    Nelson-Filho, Paulo; Silva, Lea Assed Bezerra; Silva, Raquel Assed Bezerra; de Carvalho, Fabricio Kitazono; de Queiroz, Alexandra Mussolino

    2016-01-01

    The aim of this paper is to present the clinical and radiological outcome of the treatment involving a delayed tooth replantation after an avulsed immature permanent incisor, with a follow-up of 1 year and 6 months. An 8-year-old boy was referred after dental trauma that occurred on the previous day. The permanent maxillary right central incisor (tooth 11) had been avulsed. The tooth was hand-held during endodontic therapy and an intracanal medication application with calcium hydroxide-based paste was performed. An apical plug with mineral trioxide aggregate (MTA) was introduced into the apical portion of the canal. When the avulsed tooth was replanted with digital pressure, a blood clot had formed within the socket, which moved the MTA apical plug about 2 mm inside of the root canal. These procedures developed apical revascularization, which promoted a successful endodontic outcome, evidenced by apical closure, slight increase in root length, and absence of signs of external root resorption, during a follow-up of 1 year and 6 months. PMID:27882250

  1. Replantation of permanent incisors in children using Emdogain.

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    Barrett, Edward J; Kenny, David J; Tenenbaum, Howard C; Sigal, Michael J; Johnston, Douglas H

    2005-10-01

    The aim of this study was to determine whether application of an enamel matrix protein derivative, Emdogain (Biora AB Malmo, Sweden) to the root surface of avulsed permanent incisors would improve postreplantation outcomes in a pediatric population. Between June 1999 and May 2002, 25 avulsed permanent maxillary incisors (22 centrals and three laterals) were treated with Emdogain and followed for up to 32 months, mean duration 20.6 months (range: 6.9-32.5 months). Mean patient age at the time of treatment was 12.0 years (range: 7.7-17.6 years) and mean extra-alveolar duration was 185 min (range: 100-300 min). At the end of their follow-up each of the replanted incisors demonstrated radiographic evidence of replacement root resorption and clinical evidence of ankylosis. None of the replanted teeth were affected by inflammatory root resorption and there was no evidence of infection. When compared with the control samples from Barrett and Kenny (Endod Dent Traumatol 1997;15:269-72.) and Andersson et al. (Endod Dent Traumatol 1989;5:38-47.) this sample treated with the Emdogain protocol demonstrated significantly less root resorption than either of the control samples (anova, P Emdogain protocol did not produce periodontal regeneration, it did eliminate inflammatory resorption and infection and led to significantly less root resorption compared with the two historical controls.

  2. Successful replantation of both lower legs in a 41-year- old man

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    YU Guang

    2012-02-01

    Full Text Available 【Abstract】Both severed legs were replanted in a 41-year-old man. Bilateral tibia and fibula were shortened by 4 cm equally. Tibial fixation was performed with reconstruction plate. Four weeks after the replantation, active and passive exercises were initiated in both of the knee joints. Four months after surgery, the patient was capable of walking independently for 20-30 m without the aid of crutches. After 28 months’ follow-up, plantar sensitivity was defined as S3. This patient was satisfactory with the cosmetic and functional results. Key words: Replantation; Tibia; Fibula

  3. Reconstruction of the replanted hand with latissimus dorsi muscle and serratus anterior fascia combined flap.

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    Ozçelik, Derya; Uğurlu, Kemal; Turan, Tuğrul

    2003-04-01

    Reconstruction with the latissimus dorsi muscle flap, combined with the serratus anterior fascia flap, was performed to cover two large and separate palmar and dorsal forearm skin defects in a patient, whose hand had been replanted 20 days earlier after traumatic amputation at the distal forearm level. As a result, a total forearm amputation was salvaged by microsurgical replantation and a free combined flap of the subscapular system. This new application of the combined flap allowed the reconstruction of large and separate wounds of the replanted hand, and provided gliding surfaces for tendons.

  4. Complete penile amputation during ritual neonatal circumcision and successful replantation using postoperative leech therapy.

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    Banihani, Omaya I; Fox, Janelle A; Gander, Brian H; Grunwaldt, Lorelei J; Cannon, Glenn M

    2014-08-01

    Circumcision is the most common surgical procedure in males in the United States, and minor complications are not uncommon. Major complications like partial penile amputations have been reported with successful replantation. Complete penile amputations in adult males have been described, and successful replantation has been reported with increasing success. We report a case of complete penile amputation at the penopubic junction using a Mogen clamp in a 7-day-old neonate with replantation using postoperative leech therapy. To our knowledge this is the first time leech therapy has been used postoperatively for neonatal penile amputation.

  5. Ten-digit replantation with seven years follow-up: A case report.

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    Cong, Haibo; Sui, Haiming; Wang, Chenlin; Wang, Zhumin; Yang, Qingmin; Wang, Buxing

    2010-07-01

    In this report, we present a case of successful replantation of 10-digit complete amputation and results of postoperative rehabilitation in 7 years follow-up. The rehabilitation program included psychotherapy, physical therapy, sensory re-education, and measurements. At the 7 years postoperatively, the static two-point discriminations of replanted digits ranged from 4 to 11 mm. Grasping powers ranged from 69 to 81 lb, and pinching powers ranged from 13 to 19 lb. The patient returned to the previous employment. Our experience has demonstrated that systemic postoperative rehabilitation and measurements could achieve satisfactory recovery of the sensory and motor functions of multiple-digit replantation.

  6. [Indications for replantation of lower limbs after their traumatic amputation at the shin level].

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    Milanov, N O; Gusami, G M

    1994-09-01

    From analysis of the results of replantation of 37 lower limbs at the level of the leg, which were amputated as the result of injury in 33 patients, the authors determine the tactical approach to the choice of indications for replantation. The authors believe that replantation at the level of the leg is always indicated in children if it is executable technically and the patient's somatic status presents no general contraindications. In other cases the formation of a stump and subsequent prosthetics should be considered more advisable.

  7. Replantation of an Avulsed Central Incisor after Long Extra- Alveolar Period. (Case Report

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    Seraj B

    2000-05-01

    Full Text Available A case involving the replantation of an avulsed incisor after long extra-oral period (8 days is reported. After cleaning the root surface, the tooth was soaked in fluoride gel for 20 minutes and root canal therapy was performed extraorally. The tooth was stabilized by wire and composite for six weeks. The patient has been periodically recalled and the tooth monitored for 36 months after replantation. Only minor external surface resorption was observed in the periapical area on the rodiograph, which was taken immediately before removal of the splint and the rate of subsequent replacement resorption has been acceptable. It should be considered that and extended extraoral period is not an absolute contraindication to replantation. Teeth replanted after long extra- alveolar periods can function for a long period of time and thus postpone prosthetic treatment.

  8. Considerations for double-hand replantation in a resource-constrained healthcare facility

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    Bibhuti Bhusan Nayak

    2016-01-01

    Full Text Available Bilateral-hand amputation is extremely rare and double-hand replantation is even rarer. Only one case of successful double replantation at arm level has been reported from India. We present a case of double-hand replantation at proximal palmar level in a young adult executed in a small nursing home. The patient presented 5 h after injury with limbs preserved well in ice. There were difficulties in executing such an unusual case in a small nursing home set-up. The patient is performing his activities of daily living and basic functions independently. We share our experience of this double-hand replantation with special emphasis on problems encountered.

  9. Topical and systemic anticoagulation in the treatment of absent or compromised venous outflow in replanted fingertips.

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    Han, S K; Lee, B I; Kim, W K

    2000-07-01

    Adequate venous repair is not always possible in fingertip replantation. We have used topical and systemic anticoagulation for fingertip replantation to overcome venous congestion in cases without venous repair or in cases in which there is obstruction of a repaired vein. Our technique consists of continuous external bleeding via a stab incision on the paraungal area and dripping heparinized saline solution at the incision site to maintain external bleeding. From July 1985 to December 1993, 157 fingers in 140 patients with complete amputation of the fingertip were replanted at Korea University Guro Hospital. Of these, 74 fingers in 68 patients were managed by topical and systemic anticoagulation due to the impossibility of repair or obstruction of a repaired vein. The overall survival rate of the fingertip replantations was 76%; that of the topical and systemic anticoagulation group was 64%.

  10. Finger Replantation in Sanglah General Hospital: Report of Five Cases and Literature Review

    OpenAIRE

    Agus Roy Rusly Hariantana Hamid; Gatot Triwono

    2016-01-01

    Background: Replantation is the prime treatment for amputated hands and fingers due to functional and aesthetic advantages. The absolute indications for replantation are amputations of the thumb, multiple fingers, trans metacarpal or hand, and any upper extremity in a child, regardless of the amputation level. A fingertip amputation distal to the insertion of the flexor digitorum superficialis (FDS) is also a good indication. Indications have been expanded to include amputation at nail level,...

  11. Crossover replantation after bilateral traumatic lower limb amputations: a case report

    OpenAIRE

    Fang Jun; Li Huazhuang; Dou Honglei; Chen Jingchun; Xu Aiping; Liu Wenguo; Ding Gang

    2012-01-01

    Abstract Introduction Replantation of a limb to the contralateral stump after bilateral traumatic amputations is rare. To the best of our knowledge, there are only a few reports of crossover lower limb replantation in the literature. Case presentation We treated a 37-year-old Chinese woman with bilateral lower limb crush injuries sustained in a traffic accident. Her lower limb injuries were at different anatomic levels. We performed emergency bilateral amputations followed by crossover replan...

  12. ANALYSIS OF OIL PALM SUSTAINABLE REPLANTING MODELS, A CASE AT PT. AGROWIYANA , TUNGGUL ULU, TANJUNG JABUNG BARAT, JAMBI

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    Solikhin Solikhin

    2012-09-01

    Full Text Available The oil palm replanting program is becoming of importance for the next decade as some of oil palm plantations are reaching the productivity peak. This research was aimed to select the priority of oil palm replanting strategy with respect to the related factors and impacts to the share holders of PIR Trans and KPPA plantation of PT. AGROWIYANA , and to identify key success indicators of replanting model. A discriptive research methodoligy was carried out using Analytical Hierarchy Process (AHP and Focus Group Discussion (FGD involving multi stakeholders of PT. AGROWIYANA . Results of this research indicated that financial is considered as the most important factor for replanting implemention with the total cutting using standard technology as chosen replanting strategy. The funding scheme through intensive fund rising IDAPERTABUN needs to be well prepared to involve more farmer groups.Keywords: PT. AGROWIYANA , Replanting Strategy

  13. Effect of PRD deficit-irrigation method and sodium salicylate on yield, yield components and water use efficiency of tomato

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    M. Meidanshahi

    2013-04-01

    Full Text Available To alleviate water scarcity problem in arid and semiarid regions of Iran, different irrigation methods such as deficit irrigation, pressurized irrigation and partial rootzone drying (PRD method have been suggested. In PRD method, half of the rootzone is watered and the other half is kept dry intermittently. The objective of this research was to study yield, yield components and water use efficiency (WUE of tomato, using PRD irrigation method and a growth stabilizer in two soil textures, under greenhouse conditions. The factorial experiment, based on complete randomizal design and three replications, included three irrigation managements (T1, full irrigation; T2, 50% of full irrigation, with PRD method and barrier; T3, 50% of full irrigation, with PRD method and no barrier, two levels of stabilizer (B1, spraying sodium salicylate and B2, without spraying sodium salicylate and two soil textures (S1, clay loam and S2, sandy loam. Results showed that the highest plants (176.2 cm were in T1 treatment and the shortest plants (131.3 cm were in T3 treatment. With 50% reduction of water in T2 compared to T1 treatment, number of flower stems was decreased by 15.2%. The highest and the least biomass and fruit yield were measured in T1 (506.8 and 342.5 g per plant and T3 (126.2 and 54.8 g per plant treatments, respectively. WUE was increased by 9.9% (changing from T1 to T2 and was decreased by 71.4% (changing from T2 to T3. The highest and the least fruit yield (216.7 and 174.4 g per plant were obtained in S2 and S1 soils, respectively. Sandy loam soil with production of 7.22 kg/m3 had higher WUE than clay loam soil, which produced 5.38 kg/m3. Application of stabilizer increased fruit yield by 16% and WUE by 16.86%. In general, the effect of PRD irrigation method (with barrier and spraying sodium salicylate on reducing water use and increasing productivity in greenhouse production of tomato was positive and recommendable.

  14. Light absorption of brown carbon aerosol in the PRD region of China

    Science.gov (United States)

    Yuan, J.-F.; Huang, X.-F.; Cao, L.-M.; Cui, J.; Zhu, Q.; Huang, C.-N.; Lan, Z.-J.; He, L.-Y.

    2016-02-01

    The strong spectral dependence of light absorption of brown carbon (BrC) aerosol is regarded to influence aerosol's radiative forcing significantly. The Absorption Angstrom Exponent (AAE) method has been widely used in previous studies to attribute light absorption of BrC at shorter wavelengths for ambient aerosols, with a theoretical assumption that the AAE of "pure" black carbon (BC) aerosol equals to 1.0. In this study, the AAE method was applied to both urban and rural environments in the Pearl River Delta (PRD) region of China, with an improvement of constraining the realistic AAE of "pure" BC through statistical analysis of on-line measurement data. A three-wavelength photo-acoustic soot spectrometer (PASS-3) and aerosol mass spectrometers (AMS) were used to explore the relationship between the measured AAE and the relative abundance of organic aerosol to BC. The regression and extrapolation analysis revealed that more realistic AAE values for "pure" BC aerosol (AAEBC) were 0.86, 0.82, and 1.02 between 405 and 781 nm, and 0.70, 0.71, and 0.86 between 532 and 781 nm, in the campaigns of urbanwinter, urbanfall, and ruralfall, respectively. Roadway tunnel experiments were conducted and the results further confirmed the representativeness of the obtained AAEBC values for the urban environment. Finally, the average light absorption contributions of BrC (± relative uncertainties) at 405 nm were quantified to be 11.7 % (±5 %), 6.3 % (±4 %), and 12.1 % (±7 %) in the campaigns of urbanwinter, urbanfall, and ruralfall, respectively, and those at 532 nm were 10.0 % (±2 %), 4.1 % (±3 %), and 5.5 % (±5 %), respectively. The relatively higher BrC absorption contribution at 405 nm in the ruralfall campaign could be reasonably attributed to the biomass burning events nearby, which was then directly supported by the biomass burning simulation experiments performed in this study. This paper indicates that the BrC contribution to total aerosol light absorption at shorter

  15. Replanting Affects the Tree Growth and Fruit Quality of Gala Apple

    Institute of Scientific and Technical Information of China (English)

    LIU En-tai; WANG Gong-shuai; LI Yuan-yuan; SHEN Xiang; CHEN Xue-sen; SONG Fu-hai; WU Shu-jing; CHEN Qiang; MAO Zhi-quan

    2014-01-01

    Apple replant disease (ARD) causes the inhibition of root system development, stunts tree growth and so on. To further investigate the effects of ARD on apple fruits, a 25-year-old apple orchard was remediated to establish a replant orchard between November 2008 and March 2009. A rotational cropping orchard was established on an adjacent wheat ifeld. The cultivar and rootstock-scion combination used in the newly established orchards was Royal Gala/M26/Malus hupehensis Rehd. Ripe fruits were collected in mid-August 2011 and mid-August 2012, meanwhile, the following indices were measured:yield per plant;fruit weight;the fruit shape index;the contents of anthocyanin, carotenoid and chlorophyll;the soluble sugar content in the lfesh;titratable acid;the sugar-acid ratio;ifrmness;and aroma components;apple plant ground diameter, plant height increment and the total length of the current-year shoots. The results showed that compared to rotational cropping, continuous cropping yielded statistically signiifcant reductions in fruit weight and yield per plant of 39.8 and 76.5%, respectively. However, there were no changes in the fruit shape index. The anthocyanin and carotenoid contents decreased by 81.7 and 37.7%, respectively, while the chlorophyll content increased by 251.0%. All of these differences in content were statistically signiifcant. The soluble sugar levels and sugar-acid ratio decreased by 25.4 and 60.9%, respectively, but the titratable acid levels and fruit ifrmness increased by 90.9 and 42.8%, respectively. Ten of the most important esters contributing to the apple aroma were analyzed, and the following changes were observed:hexyl acetate, butyl acetate, hexyl butyrate, acetate-2-methyl butyl, 2-methyl-hexyl butyrate, amyl acetate, butyl butyrate, 2-methyl-butyl butyrate, hexyl propionate and hexyl hexanoate decreased by 25.5, 78.4, 89.1, 55.5, 79.5, 77.2, 86.8, 69.9, 61.2, and 68.1%, respectively. The contents of three other aroma components, (E)-2-hexenal

  16. Evaluation of the Factors that Control the Time-Dependent Inactivation Rate Coefficients of Bacteriophage MS2 and PRD1

    Science.gov (United States)

    Anders, R.; Chrysikopoulos, C. V.

    2004-12-01

    Batch experiments were conducted under both static and dynamic conditions to study the effects of temperature and the presence of sand on the inactivation process of viruses. The male--specific RNA coliphage, MS2, and the Salmonella typhimurium phage, PRD1, were used as model viruses for this study. Over 100 oven--baked borosilicate glass bottles with or without Monterey sand were filled with a low--ionic--strength phosphate buffered saline solution containing both bacteriophage and incubated at temperatures of 4o, 15o, or 25oC. The results of the batch experiments indicate that the inactivation process can be represented by a pseudo first-order expression with time--dependent rate coefficients. A combination of high temperature and the presence of sand appears to produce the greatest disruption to the surrounding protein coat of MS2. However, for PRD1, the lower activation energies derived from Arrhenius plots indicate a weaker dependence of the inactivation rate on temperature. Furthermore, the presence of an air--liquid--solid interface in the dynamic batch experiment containing sand produces the greatest damage to specific viral components of PRD1 that are required for infection. These results indicate the use of thermodynamic parameters based on the pseudo first--order inactivation expression allows better prediction of the inactivation of viruses in the environment.

  17. Modeling of HCHO and CHOCHO at a semi-rural site in southern China during the PRIDE-PRD2006 campaign

    OpenAIRE

    Li, Xin; F. Rohrer; T. Brauers; Hofzumahaus, A.; Lu, K.; Shao, M.; Zhang, Y.H.; Wahner, A.

    2013-01-01

    HCHO and CHOCHO are important trace gases in the atmosphere, serving as tracers of VOCs oxidations. In the past decade, high concentrations of HCHO and CHOCHO have been observed for the Pearl River Delta (PRD) region in southern China. In this study, we performed box model simulations of HCHO and CHOCHO at a semi-rural site in PRD, focusing on understanding their sources and sinks and factors influencing the CHOCHO to HCHO ratio (RGF). The model was constrained by the simultaneous measurement...

  18. Modeling of HCHO and CHOCHO at a semi-rural site in southern China during the PRIDE-PRD2006 campaign

    OpenAIRE

    Li, X.; F. Rohrer; T. Brauers; Hofzumahaus, A.; Lu, K.; Shao, M.; Zhang, Y.H.; Wahner, A.

    2014-01-01

    HCHO and CHOCHO are important trace gases in the atmosphere, serving as tracers of VOC oxidations. In the past decade, high concentrations of HCHO and CHOCHO have been observed for the Pearl River Delta (PRD) region in southern China. In this study, we performed box model simulations of HCHO and CHOCHO at a semi-rural site in the PRD, focusing on understanding their sources and sinks and factors influencing the CHOCHO to HCHO ratio (RGF). The model was constrained by the ...

  19. Kidney diseases in Roma and non-Roma children from eastern Slovakia : are Roma children more at risk?

    NARCIS (Netherlands)

    Kolvek, Gabriel; Podracka, Ludmila; Rosenberger, Jaroslav; Stewart, Roy E.; van Dijk, Jitse P.; Reijneveld, Sijmen A.

    2014-01-01

    OBJECTIVES: To compare the occurence of primary renal diseases (PRD) in Roma and non-Roma children. METHODS: Data on all outpatients (n = 921) from a tertiary pediatric nephrology centre (<19 years) in eastern Slovakia were collected. We assessed early signs and symptoms and PRD for Roma and

  20. Kidney diseases in Roma and non-Roma children from eastern Slovakia : are Roma children more at risk?

    NARCIS (Netherlands)

    Kolvek, Gabriel; Podracka, Ludmila; Rosenberger, Jaroslav; Stewart, Roy E.; van Dijk, Jitse P.; Reijneveld, Sijmen A.

    2014-01-01

    OBJECTIVES: To compare the occurence of primary renal diseases (PRD) in Roma and non-Roma children. METHODS: Data on all outpatients (n = 921) from a tertiary pediatric nephrology centre (<19 years) in eastern Slovakia were collected. We assessed early signs and symptoms and PRD for Roma and non-Rom

  1. Functional outcome of patients undergoing replantation of hand at wrist level-7 year experience

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    Ravi Kumar Mahajan

    2013-01-01

    Full Text Available Background: Replantation is defined as reattachment of amputated limb using neurovascular and musculoskeletal structures in order to obtain recovery of limb. Re-vascularisation involves all the above steps in case of limb injuries that result in a near total amputation. Aim and Objective : To study the functional outcome of patients undergoing replantation of hand at wrist level. Material and Methods: This is a retrospective study of patients who underwent replantation of total amputation of hand at wrist level within a period of Jan 2003-June 2010. We evaluated post operative functional outcome compared to uninjured hand taking into consideration: 1. The patient′s overall satisfaction with the hand. 2. Recovery of flexor and extensor function of thumb and fingers. 3. Recovery of thumb opposition. 4. Recovery of sensations in the median and ulnar nerve distribution. 5. Ability of surviving hand to perform daily tasks. Results: There were total seventeen patients and age range was two years to 55 years. Out of 17 patients,16 were males. All the replantations were successful except for one. Summary: The results showed that, although the replanted hands were never functionally as good as the contralateral hand the patients were able to perform most of the daily activities.

  2. Continued Root Formation after Delayed Replantation of an Avulsed Immature Permanent Tooth

    Directory of Open Access Journals (Sweden)

    Nima Moradi Majd

    2014-01-01

    Full Text Available Introduction. Tooth avulsion in the young permanent dentition is a frequent finding, and its prognosis depends on the treatment of the avulsed tooth before replantation, the extra-alveolar time, the storage medium, and the patient’s general health. The present report describes management of an immature avulsed lower central incisor 90 minutes after the accident. Methods. A right lower central incisor of a 7-year-old girl was avulsed, and it was soaked in a glass of milk. 90 minutes after avulsion, replantation was performed, and the tooth was splinted; but after two weeks the replanted tooth’s pulp was necrotic. Thus, endodontic treatment was performed and root canal was filled using a calcium hydroxide and iodoform paste (Metapex. Three months later, the intracanal medication was washed out and the canal was sealed using an apical plug of calcium enriched mixture (CEM cement. Results. 20 months after replantation the tooth was completely asymptomatic, with physiologic mobility. Also, continued root formation including an apical segment beyond the artificial apical plug was observed. Conclusion. Creation of an appropriate apical barrier following the disinfection of root canal system promoted continued root-end growth in a replanted immature permanent tooth.

  3. Evaluation of laser photobiomodulation (λ 780 nm) on repair of dental replantation in rats

    Science.gov (United States)

    Bastos de Carvalho, Fabíola; Vasconcelos, Rebeca M.; Santos, Laila; dos Santos Barbosa, Artur F.; Aguiar, Marcio C.; Cangussu, Maria Cristina T.; Pinheiro, Antônio Luiz B.; Pedreira Ramalho, Luciana M.

    2014-02-01

    Up to date the success of tooth replantation is still limited. The majority of the teeth is lost due to progressive external root resorption. The aim of this study was to assess, histologically, the effect of laser photobiomodulation on repair after tooth replantation. Sixty Wistar Albinus rats had the right upper incisor extracted and then divided into 4 groups: G1 - absence of storage medium; G2 - milk u s e d as storage medium; G3 - milk used as storage medium a n d followed by GaAlAs laser irradiation on dental surfaces and at the entrance of alveolus; G4 - milk used as storage medium associated with laser irradiation as in G3 before and after replantation on the buccal and palatal mucosa every 48 hours for 15 days. The animals were sacrificed at 15, 30 and 60 days after replantation. The results showed that after 15 days G4 exhibit more intense chronic inflammation, with presence of clastic cells and moderate inflammatory root resorption (p<0.05) when compared to G3, which presented absence of those parameters. At day 30 in G1, G2 and G4 mild to moderate chronic inflammation and severe external root resorption were observed. G3 remained with no inflammation and inflammatory root resorption with 30 and 60 days of healing experimental times. The results suggest that laser irradiation on the dental entrance of the dental alveolus prior to tooth replantation has a positive biomodulative effect on the healing process in rats.

  4. Hand reconstruction using heterotopic replantation of amputated index and little fingers

    Institute of Scientific and Technical Information of China (English)

    ZHANG Gong-lin; CHEN Ke-ming; ZHANG Jun-hua; WANG Shi-yong

    2011-01-01

    In cases of severe segmental injury across the hand and wrist, but one or other fingers are still in peak condition, the fingers can be selected for replantation at the forearm bones to restore pinch function. Here we reported an unusual case with a severe crush-avulsion amputated injury to the right hand caused by a machine accident. We conducted hand reconstruction using heterotopic replantation of the amputated index and little fingers.During 19 months follow-up, the bone union healed well with satisfactory outcome. The interphalangeal and metacarpophalangeal joint of the fingers after the heterotopic replantation had a good holding activity. This is a worthwhile procedure and the patient is satisfied with the result. The major disadvantage of this method is the poor appearance of the reconstructed fingers.

  5. Lengthening of replanted or revascularized lower limbs: is length discrepancy a contraindication for limb salvage?

    Science.gov (United States)

    Parmaksizoglu, Fatih; Beyzadeoglu, Tahsin

    2002-08-01

    Some replantation cases require substantial bone shortening for primary closure. Leg-length discrepancy can be restored by lengthening of the replanted or revascularized extremities. Between 1991 and 2000, four patients with four total and two subtotal below-knee amputations had replantation or revascularization for their severely damaged extremities. All of them had extensive debridement, vascular repair, bone shortening and nerve repair for sensibility of their soles. One of the replanted extremities failed and had to undergo below-knee amputation because of sepsis. No other infection or vascular complications were encountered following the replantations or revascularizations. After bony consolidation, four legs were lengthened; for elimination of length discrepancy in three cases, and for obtaining balanced body proportion in one case in which the other leg was also amputated. In all procedures, a unilateral dynamic axial external fixator was used. The lengthening was performed from the proximal tibial metaphysis, with a subperiosteal osteotomy. Evaluation of injury according to the Mangled Extremity Severity Score (MESS) would encourage the surgeon to avoid salvage surgery with a shortened extremity, because of the required debridement of soft tissue and bone. These authors think the amount of limb shortening is not a major criterion in evaluating a traumatic total or subtotal below-knee amputation for salvage replantation or revascularization. A knee that has stable joint motion and the possibility of preservation of sensibility of the sole broadens the scope of indications for limb salvage, even with deliberate shortening that can be restored by lengthening; length discrepancy is not a contraindication for limb salvage.

  6. Evaluation of reversal osteofixation using K-wires in digital replantation

    Directory of Open Access Journals (Sweden)

    Vučetić Čedomir

    2014-01-01

    Full Text Available Introduction. Modified, reversal technique of fixation in digital replantation using K-wires was analyzed. The results obtained from the standard technique and reversal technique of fixation using K-wires were compared. Objective. The aim was to compare the results of osteofixation using K-wires in digital replantation when either standard or reversal, modified technique was used. Methods. A retrospective study included 103 replanted fingers in 72 patients. The first group included standard fixation using K-wires and the second group included fixation using K-wires, but with a modified technique. Modification consisted of the opposite order of moves during the phalanges fixation compared to the standard technique: first, K-wire was introduced intramedullary in the proximal phalanx and the top of the wire was drawn out through the skin in proximal part of the finger or hand. Second, distal part of the wire was introduced in the phalanx of the amputated part of the finger intramedullary until the wire entered the cortex. Results. Duration of bone healing after digital replantation was shorter in cases where reversal technique was used in comparison with standard technique (7.2 weeks compared to 7.5 weeks. Conclusion. The comparison of standard and reversal technique of phalangeal fixation with K-wires in digital replantation shows that both techniques are useful. Reversal technique expands the choice of operative techniques for bone fixation during the replantation. It shows some advantages and enables avoidance of vein injuries. [Projekat Ministarstva nauke Republike Srbije, br. III 41004 i br. 175095

  7. Replantation of an avulsed tooth with an extended extra oral period

    Directory of Open Access Journals (Sweden)

    Girish Kubasad

    2012-01-01

    Full Text Available In this study, we have reported a case of the replantation of a maxillary incisor with an extended extraoral period following a traumatic avulsion. After storage in normal saline, the root surface of the avulsed tooth was conditioned with citric acid and treated with a triple antibiotic solution. The tooth socket was filled with Emdogain before replantation. A 12 month, 18 month and a 5 year follow-up clinical examination revealed the patient to be asymptomatic, and the tooth was functional. The recall radiograph showed no evidence of renewed periradicular breakdown and apical root resorption.

  8. Penile replantation: report of two cases and review of the literature

    Institute of Scientific and Technical Information of China (English)

    LI Gui-zhong; HE Feng; HUANG Guang-ling; MAN Li-bo; LIU Kun; SHEN Yu-ming

    2013-01-01

    Penile amputation and successful replantation is very uncommon,and there is no routine standardized procedures for dealing with this medical condition.Here we report two cases of penile amputation and replantation involving different degrees of vascular insult leading to different pathogenesis,clinical presentation,surgical approach and prognosis.This report described the microsurgical procedure and postoperative care using bipedicled scrotal flap to achieve successful engraftment and function.A review of the published data and future methods to increase success of such surgical procedures is provided.

  9. Successful replantation of both lower legs in a 41-year- old man

    Institute of Scientific and Technical Information of China (English)

    YU Guang; LEI Hong-yu; GUO Shuang; YU Hao; HUANG Jian-hua; LIANG Sheng-hai

    2011-01-01

    Both severed legs were replanted in a 41-year-old man. Bilateral tibia and fibula were shortened by 4 cm equally. Tibial fixation was performed with reconstruction plate. Four weeks after the replantation, active and passive exercises were initiated in both of the knee joints. Four months after surgery, the patient was capable of walking independently for 20-30 m without the aid of crutches. After 28 months' follow-up, plantar sensitivity was defined as S3. This patient was satisfactory with the cosmetic and functional results.

  10. Central incisor loss after delayed replantation following avulsion: a contemporary restorative and adjunctive orthodontic management approach.

    Science.gov (United States)

    Savi, Andrea; Turillazzi, Oliviero; Cocconi, Renato; Bonanini, Mauro; Pizzi, Silvia; Manfredi, Maddalena

    2012-04-01

    Delayed replantation of an avulsed tooth may result in rapid root resorption or, more frequently, dental ankylosis with subsequent bone substitution. If this process develop slowly, it is possible to observe that tooth loss is characterized by a well conserved alveolus with regard to bone preservation, particularly in vertical dimension. This clinical case reports a dental trauma of a central incisor in a young boy characterized by tooth avulsion and its delayed replantation. After 10 years, dental ankylosis of the incisor was recorded and the patient underwent a prosthetic-orthodontic rehabilitation using CAD-CAM technology and no-prep veneers.

  11. Epidemiology of digital amputation and replantation in Taiwan: A population-based study.

    Science.gov (United States)

    Chang, Dun-Hao; Ye, Shih-Yu; Chien, Li-Chien; Ma, Hsu

    2015-10-01

    Publications on digital amputation and replantation have been mostly derived from case series in high-volume hand surgery practices, and epidemiological studies are few. This study used a population-based dataset to illustrate the incidence of digital amputation, patient and hospital characteristics, and their relationships with replantation. A claim for reimbursement dataset (2008) was provided as a research database by the Bureau of National Health Insurance, Taiwan. Patients with ICD-9-CM coded as digital amputation (885 and 886) were included. These were cross-referenced with procedure codes for replantation procedures (84.21 and 84.22). We defined the patients who underwent thumb replantation (84.21) and thumb amputation (84.01) during a single hospitalization as replantation failure. Patient and hospital characteristics were studied with statistical analysis. In total, 2358 patients with digital amputation were admitted (1859 male, 499 female), mean age 39.2 ± 15.5 years. The incidence was 10.2/100,000 person-years. The highest incidence was 14.7/100,000 person-years in the age group 45-54 years. Machinery and powered hand tools caused 68.8% of digital amputations. Thumb amputation [odds ratio (OR): 1.35, p = 0.01], private hospital (OR: 1.40, p = 0.01), medical center (OR: 2.38, p 20 digital amputations (OR: 4.23, p 65 years) had higher risk of thumb replantation failure (OR: 32.30, p = 0.045), while hospitals with >20 annual replantations had lower risk (OR: 0.11, p = 0.02). Our study of the National Health Insurance database characterized the epidemiology of digital amputation patients undergoing replantation and the facilities in Taiwan where these procedures are performed. The hospitals treating more digital amputation patients had higher attempt rates and lower thumb failure rates. Copyright © 2015. Published by Elsevier Taiwan.

  12. Different changes of soil nematode communities in replant and continuous-planting peach orchards and their indicative value for peach replant problem

    Directory of Open Access Journals (Sweden)

    Li X. Y.

    2015-09-01

    Full Text Available Long-term changes of soil nematode diversity and distribution patterns in replant peach orchard (RPO and continuous-planting peach orchard (CPPO were assessed to evaluate different effects on nematode community and function by RPO and CPPO, in relation to peach replant problem from the point of soil fauna. Observations were conducted on a silt loam soil, and soil sampling was performed four times through the growing season of peach trees in the period from 2006 to 2008 in Pinggu, Beijing. The result showed that RPO differed from CPPO by its higher abundance of plant feeding nematodes but lower abundance of bacterivore nematodes, as well as significantly higher values of plant parasite index but lower nematode biodiversity. Obviously, the absolute abundance of Paratylenchus in RPO was higher than that in CPPO, which could be a key factor for the peach replant problems from the part of soil nematode. Nematode function indices and weighted nematode fauna profile analysis were no significantly different in the two peach ecosystems, but they represented an indication of high disturbance, N-enriched, bacterial decomposition pathway.

  13. [Contralateral replantation after bilateral traumatic lower leg amputation. Case report with 6 year follow-up].

    Science.gov (United States)

    Betz, A; Stock, W; Hierner, R; Sebisch, E; Schweiberer, L

    1995-05-01

    A 66-year-old patient attempted suicide by jumping in front of a train. The lower extremities were amputated at different levels. On the right side, there was a complete amputation within the distal third of the lower leg. Proximal to the amputation site, there was an extensive soft-tissue and bone defect. On the left side, there was a crush injury of the tarsal and mid-tarsal bones. The left lower leg showed only few injuries. An ipsilateral (anatomical) replantation was not possible. In order to save one lower extremity, we decided to carry out a cross-over (contralateral) replantation of the right foot to the left lower leg. After a follow-up of six years, the patient is able to walk well with her prosthesis on the right side and the right foot hooked up to the left lower leg. Functionally, this treatment (cross-over replantation-one-side prosthesis of the lower leg) is much better than the prosthesis on both extremities, as the result has shown. Also from a psychological point of view, it seems to be better for the patient to preserve one extremity even with a cross-over replanted foot.

  14. Microsurgically aided upper lip replantation – case report and literature review

    Science.gov (United States)

    Gustafsson, Jonas; Lidén, Mattias; Thorarinsson, Andri

    2016-01-01

    Abstract A case with a patient who suffered an upper lip amputation and a lower lip laceration due to dog bite is presented. The amputated segment was replanted using microsurgical technique. The operative technique and postoperative care is presented, as well as a review of the current literature on the subject. PMID:27713916

  15. Microsurgical replantation and postoperative leech treatment of a large severed nasal segment

    DEFF Research Database (Denmark)

    Stemann Andersen, Peter; Elberg, Jens Jørgen

    2012-01-01

    The survival of a microsurgically replanted segment of nose in a 41-year-old woman was facilitated by the assistance of the medicinal leech Hirudo medicinalis. An arterial microanastomosis was made to a severed partial segment of nose with no possibility of recreating a venous anastomosis. The re...

  16. Emdogain does not prevent progressive root resorption after replantation of avulsed teeth: a clinical study.

    Science.gov (United States)

    Schjøtt, M; Andreasen, J O

    2005-02-01

    Emdogain has been shown in clinical and experimental studies to promote regeneration of all periodontal tissues: cementum with anchoring fibres, a functional, periodontal ligament and alveolar bone in connection with treatment of marginal periodontitis. The intention of this study was to analyse whether this regenerative capacity upon the periodontal ligament also worked in a trauma situation where a significant number of PDL cells have been eliminated because of unphysiologic storage or actual damage during avulsion or replantation. Furthermore if ankylosis sites already established because of earlier replantation after avulsion could be surgical removed and application of Emdogain could revert the ankylosis stage to a normal PDL situation. The first treatment situation was tested in seven patients with a total of 16 avulsed teeth with varying time of extra oral storage. The teeth were extra-orally endodontically treated and the root and socket covered with Emdogain before replantation. All teeth demonstrated subsequent ankylosis, primarily diagnosed by a percussion test. The second treatment situation where an ankylosis was already established constituted of seven patients with a total of 11 teeth because of previous replantation after avulsion. These teeth were all extracted, the ankylosis sites removed and the root and socket treated with Emdogain. After 6 months all teeth showed recurrence of ankylosis. It is concluded that Emdogain was not able to prevent or cure ankylosis.

  17. The effect of Emdogain and 24% EDTA root conditioning on periodontal healing of replanted dog's teeth.

    Science.gov (United States)

    Guzmán-Martínez, Nayelli; Silva-Herzog, Flores Daniel; Méndez, González Verónica; Martín-Pérez, Silvia; Cerda-Cristerna, Bernardino Isaac; Cohenca, Nestor

    2009-02-01

    Controversies still exist as for the regenerative role of enamel matrix derivatives and the need for removal of the periodontal ligament in replanted teeth. The purpose of this study was to evaluate the effect of Emdogain and 24% ethylenediamine tetraacetic acid (EDTA) root conditioning on periodontal healing of replanted dog's teeth. Teeth were extracted, endodontically treated and preconditioned as follows: group 1, Emdogain; group 2, Emdogain + EDTA and group 3, EDTA. Teeth were replanted after 30 min extraoral time, splinted for 15 days and animals sacrificed after 8 weeks of observation. Histological evaluation was performed using hematoxylin/eosin and Masson trichrome and results scored based on previously reported criteria for histological evaluation. Replacement root resorption was histologically diagnosed in all groups except in the negative control. A parametric analysis showed no statistically significant differences between experimental groups. Root preconditioning with Emdogain alone or in combination with 24% EDTA showed no evidence of regeneration of collagen fibers and consequently did not prevent the development of replacement root resorption on replanted dog's teeth.

  18. Simple replantation protocol to avoid ankylosis in teeth intended for orthodontic treatment

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    Yuli Nugraeni

    2009-03-01

    Full Text Available Background: Dento-alveolar trauma resulted from accidents involving the oral regions mostly affect the upper central incisors. Overjet that is beyond 5 mm and incompetent lip also contribute to increase the risk. Several literatures had already discussed different methods of replantation of avulsed teeth. However, it was not meant for further orthodontic treatment. Purpose: The objective of this review is to propose a simple replantation protocol of avulsed teeth which also prevent from ankylosis. Reviews: Protruded teeth usually need orthodontic treatment; therefore, an appropriate management should be done to avoid the development of ankylosis. Ankylosis of the periodontal ligament (PDL becomes a problem in orthodontic tooth movement in repositioned or replanted teeth. In addition, ankylosed teeth also more susceptible to root resorption. Actually, it was caused by the endodontic treatment. In particular, severely protruded or unoccluded teeth are hypofunctional, therefore have narrow PDL, thus it may facilitate to ankylosis development. Ideal management protocol such as the use of root canal sealer i.e. mineral trioxide aggregate (MTA; the using of Emdogain, and resilient wiring or semi-rigid fixation with brackets has become a solution in avulsed teeth arranged for orthodontic treatment. Nevertheless, the presence of oral surgeon, endodontist and orthodontist in the same time, and also ideal preparations after an accident was difficult to achieve. Conclusion: Considering that reducing the ongoing PDL inflammation with intracanal medicaments and maintaining the functional force during mastication is possible; it is concluded that this simple replantation protocol is likely.

  19. Eight cases of nine-digit and ten-digit replantations.

    Science.gov (United States)

    Kim, W K; Lee, J M; Lim, J H

    1996-09-01

    Amputations involving nine and all ten digits are very rare because of the different lengths of the digits, and it is also unusual to have all digits suitable for replantation. At Korea University Guro Hospital, from March 1987 to April 1992, three cases of 10-digit and five cases of 9-digit complete amputations were replanted by microsurgical technique. All eight cases involved young, healthy male patients, and the causes of amputation were either a cutter of press machine. The replantations were done under general anesthesia simultaneously on both hands by eight microsurgeons divided into a total of four teams. The operating times ranged from 19 to 31 hours, and the total amounts of transfused blood ranged from 6 to 38 pints. The warm ischemic times ranged from 10 minutes to 15 hours, and the cold ischemic times ranged from 3 to 29 hours. The sequence of replantation was radial digit to ulnar digit. In five of the eight patients, all of the replanted digits survived. Necrosis occurred in one and two digits in two patients with nine-digit replantations. Also, necrosis occurred in three digits in a patient who had had nine digits amputated by a press machine, sustaining severe crush injuries. The overall survival rate was 92 percent. In multidigit replantations involving 9 or 10 digits, there are a number of problems that must be overcome, including a long operating time, long ischemic times, and a large amount of blood loss. The long ischemic times were not critically related to survival rate. The total amount of blood transfused was reduced from 38 pints in one of the initial cases to 6 pints by intermittent use of the pneumatic tourniquet and venous anastomosis before arterial anastomosis. Static two-point discrimination ranged from 3 to 22 mm, and palm to pulp distance ranged from 0 to 7 cm, 1 to 5 years postoperatively. Grasping power ranged from 13 to 65 lb, and pinching power ranged from 5 to 26 lb, which was 42 and 50 percent of the average power of a

  20. The contributions of biomass burning to primary and secondary organics: A case study in Pearl River Delta (PRD), China.

    Science.gov (United States)

    Wang, BaoLin; Liu, Ying; Shao, Min; Lu, SiHua; Wang, Ming; Yuan, Bin; Gong, ZhaoHeng; He, LingYan; Zeng, LiMin; Hu, Min; Zhang, YuanHang

    2016-11-01

    Synchronized online measurements of gas- and particle- phase organics including non-methane hydrocarbons (NMHCs), oxygenated volatile organic compounds (OVOCs) and submicron organic matters (OM) were conducted in November 2010 at Heshan, Guangdong provincial supersite, China. Several biomass burning events were identified by using acetonitrile as a tracer, and enhancement ratios (EnRs) of organics to carbon monoxide (CO) obtained from this work generally agree with those from rice straw burning in previous studies. The influences of biomass burning on NMHCs, OVOCs and OM were explored by comparing biomass burning impacted plumes (BB plumes) and non-biomass burning plumes (non-BB plumes). A photochemical age-based parameterization method was used to characterize primary emission and chemical behavior of those three organic groups. The emission ratios (EmRs) of NMHCs, OVOCs and OM to CO increased by 27-71%, 34-55% and 67% in BB plumes, respectively, in comparison with non-BB plumes. The estimated formation rate of secondary organic aerosol (SOA) in BB plumes was found to be 24% faster than non-BB plumes. By applying the above emission ratios to the whole PRD, the annual emissions of VOCs and OM from open burning of crop residues would be 56.4 and 3.8Gg in 2010 in PRD, respectively.

  1. Maiden pear trees growth in replant soil after inoculation of rootstocks with mycorrhizal inoculum

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    Sławomir Świerczyński

    2015-03-01

    Full Text Available In the production of fruit trees it is important to set up a nursery always in a new site, alternatively to follow crop rotation rules. It is not always possible due to the size of a farm and production volume. In order to limit the effects of replant soil one can use different procedures before setting up a nursery. Chemical methods, however, must be replaced with non chemical ones due to environmental protection and reduction of production costs. In the experiment conducted in 2009-2012, growth of maiden pear trees of ‘Conference’ growing on three quince MA, MC, S1 rootstocks, cultivated in replant and non-replant soil after the use of mycorrhizal treatment, was compared. The strongest growth of maiden pear trees was obtained on non-replant soil with mycorrhizal and without mycorrhizal treatment of rootstocks. Inoculation of rootstocks influenced positively the height and fresh mass of the root system of maiden pear trees growing on two considered sites. On the other hand, inoculation did not rise the diameter of stem and number of lateral shoots of the maidens. Influence of mycorrhizal treatment of rootstocks on the length of lateral shoots was not obvious. Significantly the best results of maiden pear trees growth, except for the stem diameter, were obtained on MA quince compared to two other types. The mycorrhizal treatment gave better result of percentage obtained by maiden pear trees only in the replant site. The best efficiency of maiden pear trees in nursery production was observed for MA quince rootstock.

  2. Above-the-knee replantation in a child: a case report with a 24-year follow-up.

    Science.gov (United States)

    Durban, Claire Marie C; Lee, Seung-Yup; Lim, Hong-Chul

    2015-11-01

    Replantation of an amputated limb is generally contraindicated in crushing and traction injuries. Injury to muscle tissue and skin also creates difficulties in coverage, and bony fractures may shorten limb length which can impede lower extremity function. Numerous cases have been reported on the successful replantation of the lower limb in children; however, review of previous English literature has documented only very few replantation at the thigh level, and those with severe crushing injury resulted in subsequent amputation. We report a case of successful thigh-level replantation in a 3-year-old child who sustained a crushing-traction type of injury with a follow-up of 24 years. After the replantation, early and late complications developed but these were successfully managed. On her last visit, the patient had pain-free ambulation without assistance, had intact protective sensation distal to the injury, and was very satisfied with the outcome. Replantation of the lower limb in children with crushing or avulsion type of injuries is still a worthwhile procedure. However, both the patient and the family should be aware that multiple surgeries may be needed to accommodate to long-term complications such as joint stiffness, scar contractures, and limb length discrepancies.

  3. Long-term outcomes of microsurgical nasal replantation: review of the literature and illustrated 10-year follow-up of a pediatric case with full sensory recovery.

    Science.gov (United States)

    Marsden, Nicholas J; Kyle, Amanda; Jessop, Zita M; Whitaker, Iain S; Laing, Hamish

    2015-01-01

    We present a case of successful artery only total nose replantation in an 18-month-old child, with 10 years of follow-up and full sensory recovery despite no nerve repair. The common absence of veins for anastomosis does not prevent successful replant, as demonstrated with the use of Hirudo medicinalis use in this unique case. We comprehensively review the literature of this rare and complex injury and advocate microsurgical replantation where possible over other methods of nasal reconstruction.

  4. A novel PRD I and TG binding activity involved in virus-induced transcription of IFN-A genes.

    Science.gov (United States)

    Génin, P; Bragança, J; Darracq, N; Doly, J; Civas, A

    1995-01-01

    Comparative analysis of the inducible elements of the mouse interferon A4 and A11 gene promoters (IE-A4 and IE-A11) by transient transfection experiments, DNase 1 footprinting and electrophoretic mobility shift assays resulted in identification of a virus-induced binding activity suggested to be involved in NDV-induced activation of transcription of these genes. The virus-induced factor, termed VIF, is activated early by contact of virions with cells. It specifically recognizes the PRD I-like domain shared by both inducible elements, as well as the TG-like domain of IE-A4. This factor, distinct from the IRF-1, IRF-2 and the alpha F1 binding proteins and presenting a different affinity pattern from that of the TG protein, is proposed as a candidate for IFN-type I gene regulation. Images PMID:8559665

  5. Non-structural proteins P17 and P33 are involved in the assembly of the internal membrane-containing virus PRD1

    Energy Technology Data Exchange (ETDEWEB)

    Karttunen, Jenni; Mäntynen, Sari [Centre of Excellence in Biological Interactions, Department of Biological and Environmental Science and Nanoscience Center, University of Jyväskylä, P.O. Box 35, 40014 Jyväskylä (Finland); Ihalainen, Teemu O. [Stem Cells in Neurological Applications Group, BioMediTech, University of Tampere, Tampere (Finland); Bamford, Jaana K.H. [Centre of Excellence in Biological Interactions, Department of Biological and Environmental Science and Nanoscience Center, University of Jyväskylä, P.O. Box 35, 40014 Jyväskylä (Finland); Oksanen, Hanna M., E-mail: hanna.oksanen@helsinki.fi [Institute of Biotechnology and Department of Biosciences, University of Helsinki, Biocenter 2, P.O. Box 56 (Viikinkaari 5), FIN-00014 Helsinki (Finland)

    2015-08-15

    Bacteriophage PRD1, which has been studied intensively at the structural and functional levels, still has some gene products with unknown functions and certain aspects of the PRD1 assembly process have remained unsolved. In this study, we demonstrate that the phage-encoded non-structural proteins P17 and P33, either individually or together, complement the defect in a temperature-sensitive GroES mutant of Escherichia coli for host growth and PRD1 propagation. Confocal microscopy of fluorescent fusion proteins revealed co-localisation between P33 and P17 as well as between P33 and the host chaperonin GroEL. A fluorescence recovery after photobleaching assay demonstrated that the diffusion of the P33 fluorescent fusion protein was substantially slower in E. coli than theoretically calculated, presumably resulting from intermolecular interactions. Our results indicate that P33 and P17 function in procapsid assembly, possibly in association with the host chaperonin complex GroEL/GroES. - Highlights: • Two non-structural proteins of PRD1 are involved in the virus assembly. • P17 and P33 complement the defect in GroES of Escherichia coli. • P33 co-localises with GroEL and P17 in the bacterium. • Slow motion of P33 in the bacterium suggests association with cellular components.

  6. Process analysis and sensitivity study of regional ozone formation over the Pearl River Delta, China, during the PRIDE-PRD2004 campaign using the CMAQ model

    Directory of Open Access Journals (Sweden)

    X. Wang

    2009-12-01

    Full Text Available In this study, the Community Multiscale Air Quality (CMAQ modeling system is used to simulate the ozone (O3 episodes during the Program of Regional Integrated Experiments of Air Quality over the Pearl River Delta, China, in October 2004 (PRIDE-PRD2004. The simulation suggests that O3 pollution is a regional phenomenon in the PRD. Elevated O3 levels often occurred in the southwestern inland PRD, Pearl River estuary (PRE, and southern coastal areas during the 1-month field campaign. Three evolution patterns of simulated surface O3 are summarized based on different near-ground flow conditions. More than 75% of days featured interaction between weak synoptic forcing and local sea-land circulations. Integrated process rate (IPR analysis shows that photochemical production is the dominant contributor to O3 enhancement from 09:00 to 15:00 LST (local standard time in the atmospheric boundary layer over most areas with elevated O3 occurrence in the mid-afternoon. The simulated ozone production efficiency is 2–8 O3 molecules per NOx molecule oxidized in areas with high O3 chemical production. Precursors of O3 originating from different source regions in the central PRD are mixed during transport to downwind rural areas during nighttime and early morning, where they then contribute to the daytime O3 photochemical production. Such close interactions among precursor emissions, transports, and O3 photochemical production result in the regional O3 pollution over the PRD. Sensitivity studies suggest that O3 formation is volatile organic compound-limited in the central inland PRD, PRE, and surrounding coastal areas with less chemical aging (NOx/NOy>0.6, but is NOx-limited in the rural southwestern PRD with photochemically aged air (NOx/NOy<0.3.

  7. Replantation of an avulsive amputation of a foot after recovering the foot from the sea.

    Science.gov (United States)

    Yüksel, F; Karacaoğlu, E; Ulkür, E; Güler, M M

    2000-04-01

    A foot avulsion case, with the dismembered body part submerged in sea water for 1 hour, is presented. This report is unique in that it is the first to document the reattachment of a body part that had been submerged in sea water. It was not known how salt-water exposure would affect wound management. Differences in osmolarity and bacterial flora between the sea water and foot tissues have not caused any problems, and the patient has not suffered any vascular or infectious complications after replantation. Neurotization of the plantar surface by the tibial nerve, which was stripped off during amputation and replaced in its original traces, was the most critical part of convalescence. After management of such an interesting case, we conclude that exposure to sea water of the dismembered part should not be a contraindication for replantation surgery.

  8. Genital self-amputation or the Klingsor syndrome: Successful non-microsurgical penile replantation.

    Science.gov (United States)

    El Harrech, Y; Abaka, N; Ghoundale, O; Touiti, D

    2013-10-01

    Self-mutilations of the external genitals in psychiatric patients also known as Klingsor syndrome is a rare urologic trauma. Men with religious conflicts, low self-esteem, unresolved transsexual issues and feelings of guilt are the most vulnerable. This condition requires immediate surgical intervention. Currently replantation involves meticulous microsurgery and has become the primary method for managing these patients. In this paper, we report a case of self amputation of penis in a patient with a psychiatric history significant for schizopfrenia. Because of the unavailability of a microscope in our department, a non-microsurgical replantation without microscopic magnification was attempted. After surgery, normal appearance and function including a good normal voiding, sensation, and erections were observed.

  9. Genital self-amputation or the Klingsor syndrome: Successful non-microsurgical penile replantation

    Directory of Open Access Journals (Sweden)

    Y El harrech

    2013-01-01

    Full Text Available Self-mutilations of the external genitals in psychiatric patients also known as Klingsor syndrome is a rare urologic trauma. Men with religious conflicts, low self-esteem, unresolved transsexual issues and feelings of guilt are the most vulnerable. This condition requires immediate surgical intervention. Currently replantation involves meticulous microsurgery and has become the primary method for managing these patients. In this paper, we report a case of self amputation of penis in a patient with a psychiatric history significant for schizopfrenia. Because of the unavailability of a microscope in our department, a non-microsurgical replantation without microscopic magnification was attempted. After surgery, normal appearance and function including a good normal voiding, sensation, and erections were observed.

  10. Transient bone resorption following finger replantation: a report of 3 cases

    Institute of Scientific and Technical Information of China (English)

    Stefano Lucchina; Hillary A. Becker; Cesare Fusetti; Alexander Y. Shin

    2011-01-01

    Radiographic changes consisting of alterations in mineral content, osteopaenia or destructive neuropathy that occur following successful finger replantation have already been described. We report our experience about four fingers in three individuals in whom bone changes developed in the first three months postoperatively with complete "restitution ad integrum".Three patients, 21-49 years old (average 36 years) sustained a clean-cut amputation of four fingers. The first patient had an amputation at the base of the middle phalanx of the index finger and the second patient at the base of the proximal phalanx of the ring finger. The third had an amputation at the base of the first metacarpal bone and the proximal phalanx of the small finger in a five finger amputation. In the first case, two dorsal veins and two palmar digital arteries and nerves were repaired. In the second case, one palmar artery and one dorsal vein were reanastomosed. In the third case at the thumb, two dorsal veins and two palmar digital arteries and nerves were reconstructed. At the small finger, one dorsal vein, one palmar digital artery and two digital nerves were reconstructed. Bone fixation was achieved with two and three K-wires or tension-band wiring. Replantation was successful in all cases. Three weeks after replantation, the X-rays showed rapid development of osteopaenia in the juxtaartieular region and metaphyses of the bone. These changes were followed by subperiosteal,intracortical and endosteal bone resorption. No further surgical procedures or splintage were needed and hand therapy was not discontinued. At 10-13 weeks (average 12 weeks)postoperatively, the X-rays showed a complete recovery with new periosteal bone formation.We suggest that the radiographic changes after finger replantation are transient, first evident subperiosteally and progressing centrally. They may reflect small-vessel compromise and microinfarction and transient hyperemia secondary to neurovascular damage or to

  11. Pulp revascularization of replanted immature dog teeth after different treatment methods.

    Science.gov (United States)

    Yanpiset, K; Trope, M

    2000-10-01

    The purpose of the present study was to determine the effect of topical treatment with doxycycline and/or the application of unfilled resin to the anatomical crown on the occurrence of revascularization in reimplanted dog teeth. Ninety-six teeth in 4 young mongrel dogs were used. Eighty one teeth were atraumatically extracted and divided into four groups. Group 1, 17 teeth were kept dry for 5 min and then replanted. Group 2, 21 teeth were soaked with a freshly prepared solution of doxycycline (1 mg/20 mL saline) for 5 min before replantation. Group 3, 23 teeth were soaked with the doxycycline solution for 5 min, and then replanted. The crowns were coated with 2 layers of light cured unfilled resin. Group 4, 20 teeth were kept dry for 5 min, and then replanted. The crowns were treated as with the teeth in Group 3. Three months after surgery, radiographic evaluation revealed that 27 teeth had continued root development and 32 teeth showed arrested root development with periradicular pathosis. The remaining 17 teeth, which had arrested root development but no signs of periradicular pathosis, were all histologically evaluated for final assessment. The occurrence of revascularization according to treatment group was 29.4%, 60%, 60%, 36.8% in Group 1, 2, 3, and 4, respectively. A multiple logistic regression analysis in SAS indicated there was no significant association between vitality and dog (P = 0.7564). Soaking for 5 min in doxycycline significantly increased the revascularization rate (P = 0.024) while the addition of resin to the crown did not result in an increased incidence of pulp revascularization (P = 0.823).

  12. Unusual case of successful hand replantation with bad functional outcome: A case report

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    Milenković Saša

    2012-01-01

    Full Text Available Introduction. Traumatic hand amputation is a very severe and rare injury. Replantation and revascularization surgery requires the existence of specialized centres and well-educated teams of microsurgeons. In places where there are no such specialized centres for this kind of surgery, traumatic hand amputation is a major concern and quite a challenge, and a successfully performed replantation is a great accomplishment. Case Outline. We report a case of a successfully survived replanted hand in a 35-year-old male patient with unfortunately bad end result of the treatment. The patient with the amputated left hand (disarticulation had a surgery 4 hours after injury. The urgent surgical procedure required a debridement, the excision of the first row of the carpal bones, external fixation of the wrist, vascular anastomoses, nerve repair, tenorrhaphy, skin sutures and decompression skin incisions. The successful operation did not have a successful post-operative course due to the patient’s psychiatric problems and lack of rehabilitation at the psychiatric institution where the treatment was continued. Conclusion. Successful surgical performance can unfortunately be ruined due to inadequate further treatment course or the wrong selection for such a demanding surgery. The survival of the amputated hand can be achieved surgically, but achieving refunctioning does not always depend on surgery. It also depends on the very patient, his motivation, rehabilitation, as well as on the proper selection for such a demanding and complex surgical procedure.

  13. Racial Variation in Treatment of Traumatic Finger/Thumb Amputation: A National Comparative Study of Replantation and Revision Amputation

    Science.gov (United States)

    Mahmoudi, Elham; Swiatek, Peter R.; Chung, Kevin C.; Ayanian, John Z.

    2016-01-01

    Background Traumatic finger/thumb amputations are some of the most prevalent traumatic injuries affecting Americans each year. Rates of replantation after traumatic finger/thumb amputation, however, have been steadily declining across U.S. hospitals, which may make these procedures less accessible to minorities and vulnerable populations. The specific aim of this study was to examine racial variation in finger replantation after traumatic finger/thumb amputation. Methods Using a two-level hierarchical model, we retrospectively compared replantation rates for African-American patients with those of Whites, adjusting for patient and hospital characteristics. Patients younger than 65 with traumatic finger/thumb amputation injuries who sought care at a U.S. trauma center between 2007 and 2012 were included in the study sample. Results We analyzed 13,129 patients under 65 years of age with traumatic finger/thumb amputation. Replantation rates declined over time from 19% to 14% (p = 0.004). Adjusting for patient and hospital characteristics, African-Americans (OR=0.81; CI: 0.66–0.99; p = 0.049) were less likely to undergo replantation procedures than Whites, and uninsured patients (OR=0.73; CI: 0.62–0.84; p advancements in microsurgical techniques and the increasing use of reconstructive surgery in other fields, finger/thumb replantation rates are declining in the U.S. and vulnerable populations are less likely to undergo replantation after amputation injuries. Regionalization of care for these injuries may not only provide a higher quality care but also reduce variations in treatment. PMID:26910702

  14. Transient bone resorption following finger replantation: a report of 3 cases

    Directory of Open Access Journals (Sweden)

    Lucchina Stefano

    2011-06-01

    Full Text Available 【Abstract】Radiographic changes consisting of al- terations in mineral content, osteopaenia or destructive neu- ropathy that occur following successful finger replantation have already been described. We report our experience about four fingers in three individuals in whom bone changes de- veloped in the first three months postoperatively with com- plete “restitution ad integrum”. Three patients, 21-49 years old (average 36 years sus- tained a clean-cut amputation of four fingers. The first pa- tient had an amputation at the base of the middle phalanx of the index finger and the second patient at the base of the proximal phalanx of the ring finger. The third had an ampu- tation at the base of the first metacarpal bone and the proxi- mal phalanx of the small finger in a five finger amputation. In the first case, two dorsal veins and two palmar digital arter- ies and nerves were repaired. In the second case, one pal- mar artery and one dorsal vein were reanastomosed. In the third case at the thumb, two dorsal veins and two palmar digital arteries and nerves were reconstructed. At the small finger, one dorsal vein, one palmar digital artery and two digital nerves were reconstructed. Bone fixation was achieved with two and three K-wires or tension-band wiring. Replantation was successful in all cases. Three weeks after replantation, the X-rays showed rapid development of osteopaenia in the juxtaarticular region and metaphyses of the bone. These changes were followed by subperiosteal, intracortical and endosteal bone resorption. No further sur- gical procedures or splintage were needed and hand therapy was not discontinued. At 10-13 weeks (average 12 weeks postoperatively, the X-rays showed a complete recovery with new periosteal bone formation. We suggest that the radiographic changes after finger replantation are transient, first evident subperiosteally and progressing centrally. They may reflect small-vessel com- promise and microinfarction

  15. A conserved cluster of three PRD-class homeobox genes (homeobrain, rx and orthopedia in the Cnidaria and Protostomia

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    Mazza Maureen E

    2010-07-01

    Full Text Available Abstract Background Homeobox genes are a superclass of transcription factors with diverse developmental regulatory functions, which are found in plants, fungi and animals. In animals, several Antennapedia (ANTP-class homeobox genes reside in extremely ancient gene clusters (for example, the Hox, ParaHox, and NKL clusters and the evolution of these clusters has been implicated in the morphological diversification of animal bodyplans. By contrast, similarly ancient gene clusters have not been reported among the other classes of homeobox genes (that is, the LIM, POU, PRD and SIX classes. Results Using a combination of in silico queries and phylogenetic analyses, we found that a cluster of three PRD-class homeobox genes (Homeobrain (hbn, Rax (rx and Orthopedia (otp is present in cnidarians, insects and mollusks (a partial cluster comprising hbn and rx is present in the placozoan Trichoplax adhaerens. We failed to identify this 'HRO' cluster in deuterostomes; in fact, the Homeobrain gene appears to be missing from the chordate genomes we examined, although it is present in hemichordates and echinoderms. To illuminate the ancestral organization and function of this ancient cluster, we mapped the constituent genes against the assembled genome of a model cnidarian, the sea anemone Nematostella vectensis, and characterized their spatiotemporal expression using in situ hybridization. In N. vectensis, these genes reside in a span of 33 kb with the same gene order as previously reported in insects. Comparisons of genomic sequences and expressed sequence tags revealed the presence of alternative transcripts of Nv-otp and two highly unusual protein-coding polymorphisms in the terminal helix of the Nv-rx homeodomain. A population genetic survey revealed the Rx polymorphisms to be widespread in natural populations. During larval development, all three genes are expressed in the ectoderm, in non-overlapping territories along the oral-aboral axis, with distinct

  16. Replantation of a displaced incisor in a boy with a cleft lip and alveolus: a case report.

    Science.gov (United States)

    Schaaf, Heidrun; Kerkmann, Heiko; Pitka, Felix; Bock, Niko Christian; Attia, Sameh

    2016-09-15

    Tooth replantation after traumatic avulsion or transplantation is a challenge in oral surgery. A special method named auto-alloplastic replantation, in which a titanium post is used after extraoral endodontic treatment, combines several advantages. The treatment is performed in one step with no further endodontic intervention, no wide root canal instrumentation, no recontamination, and reduced endodontic infection. This is the first report on replantation of an ectopic tooth in a patient with a cleft lip and alveolus using this method. This case report presents the treatment of a 13-year-old white boy with a cleft lip and alveolus who had an ectopic incisor in the cleft region. His rehabilitation was performed by a tooth transposition using the auto-alloplastic replantation technique. After preparation of the displaced incisor from the vestibule, extraoral endodontic treatment followed using a titanium post prior to replantation in a newly formed socket. In the follow-up, the tooth is still in place and functioning after 2 years. This method can be used to bridge the years while a patient is young and jaw growth is incomplete until bone augmentation and implantation can be performed. The tooth will preserve the remaining alveolar ridge and help the adolescent psychologically.

  17. Transport of bacteriophage PRD1 through saturated clean sand columns as a function of pH and ionic strength

    Science.gov (United States)

    Sadeghi, G.; Schijven, J. F.; Hassanizadeh, S. M.; Behrends, T.; Gerritse, J.

    2010-12-01

    Groundwater is a major source for drinking water, because of its good microbial quality in its natural state as compared with fresh surface water. Nevertheless, it may be contaminated with pathogenic microorganisms, especially viruses, and that may hamper drinking water production. The two most significant processes controlling virus mobility in the subsurface environment are virus attachment and inactivation. Based on previous studies, many factors have been identified that impact these processes, among them, pH and ionic strength (IS) seem to have the largest influence on virus removal. The objective of this work was to investigate the effects of pH and IS on virus removal in saturated porous media. In addition, it was the objective to determine quantitative relations for these effects. In order to do so, a systematic study was conducted in columns with clean sand under saturated conditions at various pH and IS values within the range of field conditions using bacteriophage PRD1 as a model virus. These experiments were conducted in a 50-cm column with clean quartz sand under saturated conditions and various combinations of pH and ionic strength. Values of pH were 5, 6, 7 and 8 and ionic strength values were 1, 10 and 20 mM. Bacteriophage PRD1 was used as a conservative model virus for virus removal. Attachment, detachment and inactivation rate coefficients were determined from fitting the breakthrough curves. Attachment rate coefficients were found to increase with decreasing pH and increasing ionic strength. Results were used to calculate sticking efficiency values and an empirical formula for it as a function of pH and ionic strength was developed. The applicability of this empirical formula at field scale requires further investigation. Effects of pH and ionic strength on the values of the detachment rate coefficients as well as on inactivation rate coefficients of attached virus particles were also determined but required higher certainty to obtain

  18. Investigation on leukocyte profile of periparturient cows with or without postpartum reproductive disease

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    Rafiqul Islam

    2014-03-01

    Conclusions: The neutrophil% and neutrophil: lymphocyte ratio was higher in the cows with PRD during periparturient period. Thus, the increased neutrophil percentage and neutrophil: lymphocyte ratio observed at day15 postpartum is an indication of PRD in cows. The significant rise in TLC on the day of calving than prepartum and post partum days only in normal cows is physiological. It is also clear that cows suffering from ROP most likely to suffer from other post partum reproductive diseases.

  19. Observation of nighttime nitrous acid (HONO) formation at a non-urban site during PRIDE-PRD2004 in China

    Science.gov (United States)

    Su, Hang; Cheng, Ya Fang; Cheng, Peng; Zhang, Yuan Hang; Dong, Shuofei; Zeng, Li Min; Wang, Xuesong; Slanina, Jacob; Shao, Min; Wiedensohler, Alfred

    Though the importance of HONO as an OH precursor has been recognized for years, its chemical formation pathway is still not well understood. This inhibited the simulations of HONO and observation-based formation rates provided an alternative for the air quality models. However, HONO formation rate derived from certain period may be significantly influenced by uncertainties in transport and emission processes. In this study the use of large sample and scaling methods were recommended in the calculation of HONO formation rate. During the Program of Regional Integrated Experiments of Air Quality over Pear River Delta (PRIDE-PRD2004), good correlations between HONO and NO2 were found supporting the involvement of NO2 in HONO formation. An average NO2-to-HONO nighttime conversion rate CHONO of 1.6%h-1 was derived at a non-urban site Xinken. This conversion rate was comparable to other field measurements and could not be explained by gas phase reactions only. If assumed that HONO was formed only on the ground surface, the observed conversion rate could be explained by the reactions of NO2 on ground surfaces only if three deposited NO2 lead to one HONO released. The emission factor of HONO and its sampling interferences during the measurements were also evaluated in this article.

  20. New particle formation in the presence of a strong biomass burning episode at a downwind rural site in PRD, China

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Z. B.; Hu, M.; Yue, D. L.; Yang, Q.; Zhang, Y. H. [State Key Joint Lab. of Environmental Simulation and Pollution Control, Coll. of Environmental Sciences and Engineering, Peking Univ., Beijing (China)], e-mail: minhu@pku.edu.cn; He, L. Y.; Huang, X. F. [Key Lab. for Urban Habitat Environmental Science and Technology, School of Environment and Energy, Peking Univ. Shenzhen Graduate School, Shenzhen (China); Zheng, J. [Dept. of Atmospheric Science, Texas AandM Univ., College Station, Texas (United States); Zhang, R. Y. [State Key Joint Lab. of Environmental Simulation and Pollution Control, Coll. of Environmental Sciences and Engineering, Peking Univ., Beijing (China); Department of Atmospheric Science, Texas AandM Univ., College Station, Texas (United States))

    2013-09-15

    In order to characterise the features of particle pollution in the Pearl River Delta (PRD) region, a 1-month intensive campaign was conducted at the rural supersite (Kaiping) in the autumn of 2008. In total, 12 new particle formation (NPF) events are identified out of 30 campaign days. The results show that in the case of higher source and sink values, the result of the competition between source and sink is more likely the key limiting factor to determine the observation of NPF events at Kaiping. One episode with consecutive NPF events in the presence of strong biomass burning plume was observed between 10 and 15 November. The elevation of particle volume concentration (6.1 mm{sup 3}/cm{sup 3}/day) is due to the coaction by the local biomass burning and secondary transformation. Organics and sulphates are the major components in PM{sub 1}, accounting for 42% and 35% of the mass concentration, respectively. In this study, a rough estimation is applied to quantify the contributions of diverse sources to the particle number concentration. On average, the primary emission and secondary formation provide 28 and 72% of particle number concentration and 21% and 79% of mass concentration, respectively.

  1. Replanting/underplanting strategy for old coconut plantations in Papua New Guinea

    Directory of Open Access Journals (Sweden)

    Ollivier Jean

    2001-11-01

    Full Text Available In most producing countries, the population of coconut palms is growing old, and ways of replacing them are rarely implemented to ensure that production is maintained and the future of the industry and its profitability are safeguarded. Rehabilitating/replanting coconut plantations and adopting appropriate intercropping systems is one of the main challenges to be taken up for the future of coconut in the Asia-Pacific region. The example of Papua New Guinea (PNG reveals one of the lowest yields per hectare among the countries in the Asia-Pacific zone. Almost 106,000 ha were planted between 1910 and 1940, amounting to around 40% of the current coconut plantings, hence 80 to 100,000 ha can be expected to disappear in the next twenty years. Faced with this forecast, the PNG Cocoa and Coconut Research Institute (PNG CCRI launched several operations, beginning with the creation of a coconut research centre on the PNG mainland: examination of a replanting strategy for old coconut plantings, based on hybrid planting material, distribution of improved planting material through the creation of a seed garden, and development of a system for controlling pest populations in high-risk zones. The experiments set up at the station are designed to optimize the felling date for old coconut palms, by measuring the effects of competition with the underplanted hybrids, and to determine from an economic point of view the best strategy to be applied for implementing rehabilitation and/or replanting programmes in old coconut plantings. This paper describes the results of these operations.

  2. Management of external perforating root resorption by intentional replantation followed by Biodentine restoration

    Directory of Open Access Journals (Sweden)

    Preeti Jain Pruthi

    2015-01-01

    Full Text Available Resorption of tooth structures can occur as a result of physiological, pathological, and idiopathic factors. Early diagnosis and appropriate treatment can prevent its serious complications. This case report presents surgical endodontic management of a trauma-induced perforating external root resorption, which was diagnosed with the help of cone beam computed tomography. Following root canal treatment, intentional replantation of the tooth was performed so as to expose the opening of the resorption defect to allow for complete debridement and closure. Eighteen months follow-up showed arrest of root resorption, and progressive healing of the defect.

  3. Management of external perforating root resorption by intentional replantation followed by Biodentine restoration.

    Science.gov (United States)

    Pruthi, Preeti Jain; Dharmani, Umesh; Roongta, Ruchika; Talwar, Sangeeta

    2015-01-01

    Resorption of tooth structures can occur as a result of physiological, pathological, and idiopathic factors. Early diagnosis and appropriate treatment can prevent its serious complications. This case report presents surgical endodontic management of a trauma-induced perforating external root resorption, which was diagnosed with the help of cone beam computed tomography. Following root canal treatment, intentional replantation of the tooth was performed so as to expose the opening of the resorption defect to allow for complete debridement and closure. Eighteen months follow-up showed arrest of root resorption, and progressive healing of the defect.

  4. Influences of relative humidity and particle chemical composition on aerosol scattering properties during the 2006 PRD campaign

    Science.gov (United States)

    Liu, Xingang; Cheng, Yafang; Zhang, Yuanhang; Jung, Jinsang; Sugimoto, Nobuo; Chang, Shih-Yu; Kim, Young J.; Fan, Shaojia; Zeng, Limin

    In situ measurements of the physical, chemical, and optical properties of aerosols were carried out in Guangzhou city, China, from 1 to 31 July 2006 during the Pearl River Delta (PRD) Campaign. The light extinction coefficient of the ambient atmosphere, the aerosol scattering coefficient under dry conditions, the aerosol absorption coefficient under ambient conditions, NO 2 concentration, and relative humidity (RH) were measured by transmissionmeter, an integrating nephelometer, a multi-angle absorption photometer (MAAP), a NO X analyzer, and an automatic meteorological station, respectively. Meanwhile, the molecular scattering coefficient was calculated by the Rayleigh scattering function using the US Standard Atmosphere. A method to calculate the aerosol hygroscopic growth factor f(RH), defined as the ratio of the aerosol scattering coefficient under a wet condition to that under a dry condition (40% RH), is proposed based on these optical parameters. The mean and standard deviation aerosol hygroscopic growth factors at 80% RH ( f(RH)=80%) in Ganzhou were 2.04±0.28, 2.29±0.28, and 2.68±0.59 for urban aerosols, mixed aerosols, and marine aerosols, respectively, with the air mass classification being based on the air mass source region. The relationship between f(RH) and RH is fitted by empirical equations and the fitting parameters are calculated. The relationships between f(RH)=80% and total carbon mass fraction (TCF) in PM 2.5, the water-soluble mass fraction (WSF) in PM 10, and the sea-salt aerosol mass fraction (SSF) in PM 10 reveal that the hygroscopic properties of the observed aerosol have a good positive correlation with the WSF and SSF, but have a negative correlation with the TCF.

  5. Replantation of Displaced Underlying Successor and Marsupialization of Radicular Cyst associated with a Primary Molar

    Science.gov (United States)

    Ravi, GR

    2015-01-01

    ABSTRACT Radicular cysts are by far the most common cystic lesions of the jaw. However, those arising from primary teeth are comparatively rare, comprising only 0.5 to 3.3%. The aim of this paper is to present clinical, radiographic and histopathological characteristics of radicular cyst associated with a primary mandibular molar causing unusual displacement of the permanent successor. Extraction of primary tooth along with extirpation of cyst was done under local anesthesia. The displaced premolar was also extracted and then replanted in the socket after proper alignment. Healing was uneventful and the space of missing primary molar was maintained by band and loop space maintainer. The relationship between intracanal medicaments and rapid growth of cyst, as mentioned in literature was observed in our case too. Thus, pulpotomy treated primary teeth should receive periodic postoperative radiographic examination and absence of clinical symptoms does not mean that a pulpotomy treated tooth is healthy. How to cite this article: Lamba G, Ravi GR. Replantation of Displaced Underlying Successor and Marsupialization of Radicular Cyst associated with a Primary Molar. Int J Clin Pediatr Dent 2015;8(1):70-74. PMID:26124586

  6. Replantation of Displaced Underlying Successor and Marsupialization of Radicular Cyst associated with a Primary Molar.

    Science.gov (United States)

    Lamba, Gagandeep; Ravi, G R

    2015-01-01

    Radicular cysts are by far the most common cystic lesions of the jaw. However, those arising from primary teeth are comparatively rare, comprising only 0.5 to 3.3%. The aim of this paper is to present clinical, radiographic and histopathological characteristics of radicular cyst associated with a primary mandibular molar causing unusual displacement of the permanent successor. Extraction of primary tooth along with extirpation of cyst was done under local anesthesia. The displaced premolar was also extracted and then replanted in the socket after proper alignment. Healing was uneventful and the space of missing primary molar was maintained by band and loop space maintainer. The relationship between intracanal medicaments and rapid growth of cyst, as mentioned in literature was observed in our case too. Thus, pulpotomy treated primary teeth should receive periodic postoperative radiographic examination and absence of clinical symptoms does not mean that a pulpotomy treated tooth is healthy. How to cite this article: Lamba G, Ravi GR. Replantation of Displaced Underlying Successor and Marsupialization of Radicular Cyst associated with a Primary Molar. Int J Clin Pediatr Dent 2015;8(1):70-74.

  7. Long Term Follow-Up of a Successful Lower Limb Replantation in a 3-Year-Old Child

    Directory of Open Access Journals (Sweden)

    Akbar Jaleel Zubairi

    2015-01-01

    Full Text Available Replantation of the lower extremity has controversial indications but nevertheless it may be considered in carefully selected patients who present early and are expected to show good functional recoveries. Here we present a successful replantation in a 3-year-old boy who has made excellent recovery with no functional deficit evident at 12 years of follow-up. He sustained a traumatic amputation at the level of distal tibia when he fell of a “Qing Qi” (motorcycle rickshaw. Replantation was attempted at 8 hours cold ischemia time with the tibia shortened 4 cm and all tendons, vessels, and nerves repaired. Patient required a second procedure during the same hospital stay for skin coverage. Patient made good recovery with ambulation without support at 6 months, less than 3 cm limb length discrepancy, plantar and dorsiflexion power 4/5, and recovery of sensation over the foot. Now at 12 years of follow-up patient has a normal gait and has integrated into society with no functional deficit. Considering the functional outcome of our case, replantation should be attempted whenever possible and feasible especially in children.

  8. Inactivated Bone Replantation with Preservation of the Epiphysis in Children with Osteosarcoma- Clinical Report of Two Cases

    Institute of Scientific and Technical Information of China (English)

    YUXiuchun; LIUXiaoping; ZHOUYin; LIKaihua; QUZaiping

    2005-01-01

    Objective: To evaluate the value of inactivated bone replantation with preservation of the epiphysis following the effective chemotherapy in avoiding postoperative discrepancy of the affected limb in children with osteosarcoma. Methods: Two children (aged 5 and 10 years, 1 male and 1 female) with osteosarcoma underwent inactivated bone replantation with preserving epiphysis following chemotherapy (MMIA protocol, including high-dose methotrexate, adriamycin and ifosfamide). After two cycles of preoperative chemotherapy, pain vanished, the local mass shrank and there was no pain on pressing the affected parts. Sera AKP and LDH were reduced to normal levels; marked shrinkage and sclerotic changes and good margin of lesions were seen on plain radiographs and MR images. Two courses of the same protocol as preoperative chemotherapy were administered postoperatively. Results: Postoperative histological examination of the specimens demonstrated absence of vital tumor cells. Incisions healed well and no complications occurred. The replanted inactivated bone healed with host at 6 months after operation.In the two patients, no evidence was seen of metastasis and recurrence and discrepancy of the affected limbs in postoperative 36 and 48 months. Functions of the affected limbs were satisfactory. Conclusion:Inactivated bone replantation with preserving epiphysis was a viable option for osteosarcoma in children.The long-term outcomes remain to be further proven.

  9. Efficacy of enamel matrix derivatives (Emdogain) in treatment of replanted teeth--a systematic review based on animal studies.

    Science.gov (United States)

    Wiegand, Annette; Attin, Thomas

    2008-10-01

    The objective of the current systematic review was to evaluate the efficacy of enamel matrix derivative (EMD) (Emdogain) on healing of replanted or autotransplanted permanent teeth. A review of the published literature [search term: (Emdogain OR enamel matrix derivative OR enamel matrix protein] AND [avulsion OR replantation OR autotransplantation)] was conducted by two independent investigators according to defined selection criteria. For data extraction of the identified animal studies, the following histomorphometric findings were considered: (i) healed PDL, (ii) surface resorption, (iii) inflammatory resorption and (iv) replacement resorption. The heterogeneity of data collection and the small amount of identified publications did not allow for statistical analysis. Four controlled trials (CT) conducted in animals, but no randomized controlled trials (RCT) or clinical controlled trials (CCT) could be received from the systematic search. From the selected studies, two CT gave evidence of EMD treatment to be effective in inducing healing of replanted teeth, while one CT found no differences between EMD treated teeth and controls. Finally, one CT compared EMD and sodium fluoride application, but revealed no differences between the treatments. The data of controlled trials available are limited and conflicting. No firm conclusion regarding the efficacy of EMD application on healing of replanted or autotransplanted permanent teeth can be drawn because of lack of RCT and CCT.

  10. The effect of splint material and thickness on tooth mobility after extraction and replantation using a human cadaveric model.

    Science.gov (United States)

    Kwan, Steven C; Johnson, James D; Cohenca, Nestor

    2012-08-01

    Although current guidelines for the treatment of traumatic injuries recommend the use of 'flexible' splints, the precise definition of what is considered flexible versus rigid has not been rigorously defined, leaving the clinician with a wide range of options for this critical factor. The purpose of this study was to quantify and compare the effect of eight different splints on tooth mobility after extraction and replantation using a human cadaveric model. Following strict selection criteria including complete root maturation, lack of periodontal disease, normal bone levels, and crown integrity, a maxillary central incisor was atraumatically extracted and splinted with eight different splints. The experimental splints included a 20-pound test (9.072-kilogram test) [corrected] monofilament nylon-composite splint and six wire-composite splints made of wires of 0.012' (0.3 mm), 0.016' (0.4 mm), or 0.020' (0.5 mm) diameter stainless steel (SS) or nickel titanium (NT). A direct composite splint represented the most rigid type of splint. These eight splints were applied five times each, and tooth mobility was measured before and after each splint was applied. The average splint effect, defined as the difference between the presplint and the postsplint measurements quantified using the Periotest, was calculated for each splint and compared. No significant differences were found between the nylon-composite and the wire-composite splints. There was significantly less tooth mobility with the direct composite splint compared to all other splints. In conclusion, the results of this study suggest that nylon and SS or NT wires up to 0.016' diameter are significantly more flexible than direct composite splints and thus may be better suited for the splinting and management of traumatized teeth. © 2011 John Wiley & Sons A/S.

  11. Knowledge of teachers and students in physical education's faculties regarding first-aid measures for tooth avulsion and replantation.

    Science.gov (United States)

    Jorge, Kelly Oliva; Ramos-Jorge, Maria Letícia; de Toledo, Flávia Fonseca; Alves, Laila Caldeira; Paiva, Saul Martins; Zarzar, Patrícia Maria

    2009-10-01

    The aim of the present cross-sectional study was to investigate the knowledge of undergraduate students and teachers at all physical education courses in the city of Belo Horizonte (Brazil) regarding first-aid measures to be taken following tooth avulsion as well as the need for the preventative use of mouth guards. The sample consisted of 442 individuals (Group 1: 53 teachers; Group 2: 389 undergraduate students). Data collection was carried out with the administration of a questionnaire with both objective and subjective questions addressing definitions, first-aid measures in cases of avulsion and tooth replantation, together with an assessment of the use and indication of mouth guards. Data analysis involved descriptive statistics and the chi-square test. The results revealed that 45.1% of the participants in both groups knew what a tooth replantation was. However, 91.6% judged themselves incapable of performing an immediate replantation. Among the overall sample, 45.9% has no knowledge on first-aid measures regarding tooth avulsion; sending the patient with an avulsed tooth to the dentist was the most often cited measure (42.3%). Immediate replantation was cited by 20.6% of the individuals in Group 1 and 5.9% of the individuals in Group 2 (P = 0.009). Regarding the storage medium, 17.1% of the individuals would keep the avulsed tooth in a dry medium. The majority of participants (58.3%) stated that the ideal extra-alveolar time for replantation was more than 360 min. Although 74% of the overall sample stated having knowledge of mouth guards, few reported making use or indicating the use of this piece of equipment. The present study revealed that the majority of teachers and undergraduate students of physical education courses do not have adequate knowledge regarding first-aid measures for tooth avulsion and do not use or indicate the use of mouth guards during sports activities.

  12. The characteristics and origins of carbonaceous aerosol at a rural site of PRD in summer of 2006

    Directory of Open Access Journals (Sweden)

    W. W. Hu

    2012-02-01

    Full Text Available Both organic carbon (OC and elemental carbon (EC were measured during PRIDE-PRD 2006 summer campaign by using a semi-continuous thermal-optical carbon analyzer at a rural site, Back Garden (BG, which is located 50 km to the northwest of Guangzhou City. Together with the online EC/OC analyzer, various kinds of instruments related to aerosol chemical properties were employed here, which provided a good opportunity to check data quality. The concentrations of OC correlated well with the mass of organic matter (OM and water soluble organic carbon (WSOC, implying the reliability of the data measured in this campaign. The average OC concentrations in fine particle for three typical periods during the campaign (local emission influence, typhoon and precipitation and normal days were 28.1 μgC m−3, 4.0 μgC m−3 and 5.7 μgC m−3, respectively; and EC were 11.6 μgC m−3, 1.8 μgC m−3, and 3.3 μgC m−3, respectively. The diurnal patterns of EC and OC during the campaign were higher at night and in early morning than daytime, which was probably caused by the primary emission and accumulation in the occurrence of low boundary layer. Compared with the constant diurnal enhancement ratios of EC, the enhancement ratio of OC (OC versus (CO-CObackground kept in a relative high level in the afternoon, with a similar diurnal profile to oxygenated organic aerosol (OOA, due to the strong photochemical formation of OC. Here, a modified EC tracer method was used to estimate the formation of secondary organic carbon (SOC. These results showed that the average SOC concentration (normal days at BG site was about 2.0 ± 2.3 μgC m−3, and the SOC fraction in OC could reach up to 80% with the average of 47%. The modified approach in this study proved to be effective and reliable for SOC estimation based on good correlations between estimated SOC versus OOA or WSOC, and

  13. Foster replantation of fingertip using neighbouring digital artery in a young child.

    Science.gov (United States)

    Xu, Jing-Hong; Gao, Zheng-Jun; Yao, Jing-Ming; Tan, Wei-Qiang; Dawreeawo, Javed

    2010-06-01

    Reconstruction of an amputated fingertip in a young child demands special techniques for success. We report a 2.5-year-old female patient with an amputated left index fingertip with the vascular defect being too severe to perform the usual replantation. Comparing several methods, we used the neighbouring digital artery as the feeding artery to perform foster replantation. Finally, the patient was satisfied with the appearance and function of her fingers. The clinical case, techniques, results are described and discussed. We consider it a useful technique, especially for those with a rather severe vascular defect. A 2.5-year-old girl suffered a crush amputation of the left index fingertip. Only the flexor tendon of the amputated fingertip was connected to the proximal finger tissue and the blood supply was completely lost (Figure 1). The distal amputated fingertip was fixed using Kirschner wire under general anaesthesia. Then, microsurgery operation was carried out immediately to replant this amputated fingertip. Both ulnar and radial digital arteries were avulsed, while the dorsal vein was intact and the digital nerve was also surviving. The integrity of blood vessels was too traumatised to connect to the proximal part. In the case of the distal part of the ulnar artery of the injured index finger, the blood supply was established by anastomosing the distal end of the amputated tip and the radial artery of the middle finger, which was the feeding artery (Figure 2). A 11/0 nylon suture was used. The dorsal vein and digital nerve were repaired by means of microsurgical anastomosis. The wound was covered with the dorsal skin of the middle finger and the palmar skin of the index finger to form a skin pedicle, and then, immobility of the two fingers was maintained to prevent avulsion. The index tip obtained good blood supply and survived completely (Figure 3). Detachment of the index and middle finger was performed after 3 weeks, and both of the fingers showed good

  14. 损害控制下的断指再植术%Treatment of digital replantation and shifted replantation under damage control

    Institute of Scientific and Technical Information of China (English)

    邢进峰; 丁伟航; 陈欢欢; 孙西涛; 沈金明; 童良春; 李飞; 徐海孺; 蒋云甫

    2015-01-01

    Objective To investigate the clinical application of damage control in severe multiple trauma with amputation injury at fingers.Methods Two cases of multi-trauma were included in this study,with ISS (Injury Severity Score) higher than 25.In case 1,the patient was diagnosed as left parietal subdural hematoma,left parietal bone fractures,intracranial pneumatosis,scalp defect in the left parietal area,rupture of superficial and deep flexor tendon of the left index and middle finger,rupture of the left extensor muscle,right ulnar nerve injury and amputation injury on the right thumb.In case 2,the patient were diagnosed as the left pulmonary contusion with hemopneumothorax,multiple rib fractures,the 7th cervical spine fracture,injuries on the right hand and scalp laceration.Both patients were treated under damage control and multi-department cooperation.Severed digits were preserved with sterile gauze sterile gloves at 2℃ to 4℃.The first patient was treated with in situ replantation within 63 hours after the injury.The second patient was treated with shifted replantation within 103 hours,the middle finger was shifted to reconstruct the thumb and the ring finger was shifted to reconstruct the index finger.Results All the fingers in case 1 survived,with satisfying flexion and extension function but unsatisfying sense of pain and touch.The shifted fingers all survived in case 2.Necrosis occurred partly on the proximal margin of the shifted fingers,while the defect healed after debridement and skin grafting.Recovery of finger flexion and extension was unsatisfying.Conclusion Damage control could raise the early rescue success rate of severe multiple injury and survival rate effectively.Delayed replantation and shifted replantation could reduce disability rate of patients with severe multiple trauma with severed finger injury.%目的 探讨损害控制在严重多发伤伴手指离断伤患者中的临床应用.方法 多发伤患者2例,严重度评分(ISS) ≥25

  15. [Cross-hand replantation in bilateral upper limb amputation: An anatomical emergency].

    Science.gov (United States)

    Andre, A; Rongieres, M; Laffosse, J-M; Pailhe, R; Lauwers, F; Grolleau, J-L

    2015-08-01

    Bilateral amputations of upper limbs are excessively rare clinical situations. We report an exceptional clinical case of bilateral amputation of upper limbs at different levels: destruction of the right hand and left transhumeral amputation in a patient after an attempted suicide on train lines. This special situation led us to perform a cross-hand replantation of the left hand to the right forearm. Only 4 other similar cases have been published in the literature. Once the surgical indication had been formulated collectively, and taking into account all the ethical issues surrounding such a decision, we had to solve the issue of inverting anatomical structures in emergency. We have provided a detailed description of our surgical technique. The aim was to save at least one organ used for grasping. The result obtained is presented and reviewed.

  16. Ethanol and lactic acid production using sap squeezed from old oil palm trunks felled for replanting.

    Science.gov (United States)

    Kosugi, Akihiko; Tanaka, Ryohei; Magara, Kengo; Murata, Yoshinori; Arai, Takamitsu; Sulaiman, Othman; Hashim, Rokiah; Hamid, Zubaidah Aimi Abdul; Yahya, Mohd Khairul Azri; Yusof, Mohd Nor Mohd; Ibrahim, Wan Asma; Mori, Yutaka

    2010-09-01

    Old oil palm trunks that had been felled for replanting were found to contain large quantities of high glucose content sap. Notably, the sap in the inner part of the trunk accounted for more than 80% of the whole trunk weight. The glucose concentration of the sap from the inner part was 85.2g/L and decreased towards the outer part. Other sugars found in relatively low concentrations were sucrose, fructose, galactose, xylose, and rhamnose. In addition, oil palm sap was found to be rich in various kinds of amino acids, organic acids, minerals and vitamins. Based on these findings, we fermented the sap to produce ethanol using the sake brewing yeast strain, Saccharomyces cerevisiae Kyokai no.7. Ethanol was produced from the sap without the addition of nutrients, at a comparable rate and yield to the reference fermentation on YPD medium with glucose as a carbon source. Likewise, we produced lactic acid, a promising material for bio-plastics, poly-lactate, from the sap using the homolactic acid bacterium Lactobacillus lactis ATCC19435. We confirmed that sugars contained in the sap were readily converted to lactic acid with almost the same efficiency as the reference fermentation on MSR medium with glucose as a substrate. These results indicate that oil palm trunks felled for replanting are a significant resource for the production of fuel ethanol and lactic acid in palm oil-producing countries such as Malaysia and Indonesia. Copyright 2010 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  17. Modeling of air quality with a modified two-dimensional Eulerian model: A case study in the Pearl River Delta (PRD) region of China

    Institute of Scientific and Technical Information of China (English)

    CHENG Yan-li; BAI Yu-hua; LI Jin-long; LIU Zhao-rong

    2007-01-01

    A modified two-dimensional Eulerian air quality model was used to simulate both the gaseous and particulate pollutant concentrations during October 21-24, 2004 in the Pearl River Delta (PRD) region, China. The most significant improvement to the model is the added capability to predict the secondary organic aerosols (SOA) concentrations because of the inclusion of the SOA formation chemistry. The meteorological input data were prepared using the CALMET meteorological model. The concentrations of aerosol-bound species such as NO3-, NH4+, SO42-, and SOA were calculated in the fine particle size range (<2.5 μm). The results of the two-dimensional model were compared to the measurements at the ground level during the PRD Intensive Monitoring Campaign (IMC). Overall, there were good agreements between the measured and modeled concentrations of inorganic aerosol components and O3. Both the measured and the modeled results indicated that the maximum hourly O3 concentrations exceeded the China National Air Quality Standard. The predicted 24-h average SOA concentrations were in reasonable agreement with those predicted by the method of minimum OC/EC ratio.

  18. Modeling of HCHO and CHOCHO at a semi-rural site in southern China during the PRIDE-PRD2006 campaign

    Science.gov (United States)

    Li, X.; Rohrer, F.; Brauers, T.; Hofzumahaus, A.; Lu, K.; Shao, M.; Zhang, Y. H.; Wahner, A.

    2014-11-01

    HCHO and CHOCHO are important trace gases in the atmosphere, serving as tracers of VOC oxidations. In the past decade, high concentrations of HCHO and CHOCHO have been observed for the Pearl River Delta (PRD) region in southern China. In this study, we performed box model simulations of HCHO and CHOCHO at a semi-rural site in the PRD, focusing on understanding their sources and sinks and factors influencing the CHOCHO to HCHO ratio (RGF). The model was constrained by the simultaneous measurements of trace gases and radicals. Isoprene oxidation by OH radicals is the major pathway forming HCHO, followed by degradations of alkenes, aromatics, and alkanes. The production of CHOCHO is dominated by isoprene and aromatic degradation; contributions from other NMHCs are of minor importance. Compared to the measurement results, the model predicts significant higher HCHO and CHOCHO concentrations. Sensitivity studies suggest that fresh emissions of precursor VOCs, uptake of HCHO and CHOCHO by aerosols, fast vertical transport, and uncertainties in the treatment of dry deposition all have the potential to contribute significantly to this discrepancy. Our study indicates that, in addition to chemical considerations (i.e., VOC composition, OH and NOx levels), atmospheric physical processes (e.g., transport, dilution, deposition) make it difficult to use the CHOCHO to HCHO ratio as an indicator for the origin of air mass composition.

  19. Histopathological evaluation of the effects of variable extraoral dry times and enamel matrix proteins (enamel matrix derivatives) application on replanted dogs' teeth.

    Science.gov (United States)

    Barbizam, Joao V B; Massarwa, Rasha; da Silva, Lea Assed Bezerra; da Silva, Raquel Assed Bezerra; Nelson-Filho, Paulo; Consolaro, Alberto; Cohenca, Nestor

    2015-02-01

    The extra-alveolar dry period and storage medium in which the tooth was kept prior to replantation remain the critical factors affecting the survival and regeneration of the damaged periodontium. When the replantation is delayed, replacement root resorption is the most common complication following replantation of an avulsed tooth. The aim of this histological study was to evaluate the periodontal healing of replanted dogs' teeth after 20 min (short) and 60 min (long) extraoral dry time with and without the application of enamel matrix proteins. Eighty mature premolar roots (40 teeth) maxillary and mandibular premolars were extracted, the root canals were accessed, instrumented, and filled using a lateral condensation technique, and the access cavity was restored with amalgam. Each root was randomly assigned to one of experimental groups: Groups I and II: Roots were replanted after an extraoral dry time of 20 min. In group II, Emdogain(®) (Biora, Malmo, Sweden) was applied directly to the external root surface with complete coverage. Groups III and IV: Roots were replanted after an extraoral dry time of 60 min. In group IV, Emdogain(®) was applied to the whole external root surface before replantation. Roots that replanted within a total extraoral dry time of 10 min were used as negative controls, while those replanted after 90 min of extraoral dry time were assigned as positive controls. After 4 months, the dogs were euthanized, and the maxillary and mandibular processes were processed for histology and microscopically evaluated. Statistical analysis showed no significant differences (P = 0.1075) among the experimental groups. The results of this study show that 20 min of extraoral dry time is as detrimental to the PDL cells as 60 or 90 min of extraoral dry time, with avulsed dogs' teeth, even when replanted with an inductive material such as EMD. This study provides strong evidence in relation to the threshold of the extraoral dry time of avulsed teeth

  20. Toe-to-hand transfer from a cross-foot replantation in a traumatic four-extremity amputation.

    Science.gov (United States)

    Yildirim, Serkan; Akan, Mithat; Aköz, Tayfun

    2005-10-01

    Treatment of mutilating hand injuries often requires multiple innovative procedures. This report describes a case of multi-limbed amputations from a train injury and the extraordinary microsurgical approaches for a two-hand reconstruction. The first stage of the procedure was a cross replantation of the left foot to the right leg. The second stage was a combined second and third toe transfer from the cross replantation of the left foot to the right hand, and a sensate fibular osteocutaneous flap transfer for left hand reconstruction. Satisfactory function was restored, including good protective sensation. These kinds of extraordinary microsurgical approaches are useful salvage procedures for hand reconstruction, when presented with a case of multi-limb amputation.

  1. Successful treatment of a radicular groove by intentional replantation and Emdogain therapy: four years follow-up.

    Science.gov (United States)

    Al-Hezaimi, Khalid; Naghshbandi, Jafar; Simon, James H S; Rotstein, Ilan

    2009-03-01

    Radicular groove is an anatomical malformation that often causes severe periodontal defects. Treatments of such an anomaly present a clinical challenge to the operator. Presented is a case of successful treatment of radicular groove associated with a maxillary lateral incisor of a 15-year-old girl. A combination of endodontics, intentional replantation, and Emdogain therapy was used. At 4-year follow-up, the patient was comfortable and complete resolution of the periapical pathology was evident.

  2. Evaluating Emdogain and healing of replanted teeth using an intra-individual experimental-control study design.

    Science.gov (United States)

    Fridström, Margareta; Schollin, Jens; Crossner, Claes-Göran

    2008-06-01

    The purpose of the present investigation was to use an intra-individual experimental-control study design to explore if application of Emdogain prior to re-plantation after a dry extra-alveolar period of 60 min would promote a favorable healing of the periodontal ligament cells. Ten patients, for whom already decisions had been taken to extract two maxillary premolars because of crowding, participated in the study. The teeth were extracted and endodontic treatment was performed extra orally. The experimental tooth and its alveolar socket were covered with Emdogain prior to replantation. The contra lateral tooth served as a control and was replanted without any prior treatment. The teeth were stabilized with a retainer for 3-7 days and the patients were followed up every third week. After 13 weeks, the teeth were finally extracted and prepared for histological examination. Radiographs were taken before the study period, at day 29 and prior to the final extraction. The results were in favor of Emdogain, but the overall difference between the Emdogain-treated tooth and its control was rather small, and it seemed questionable if the registered differences could be of any obvious practical clinical importance. Histologically, all the teeth showed some degree of pathology after such a long dry extra-oral time and the outcome seemed to be more correlated to the individual than to the treatment. Given more favorable conditions regarding storage medium and/or extra-oral time, Emdogain might still be of value for an uncomplicated healing after replantation.

  3. Surgical Re-entry of an Intentionally Replanted Periodontally Compromised Tooth Treated with Platelet Rich Fibrin (PRF): Hopeless to Hopeful.

    Science.gov (United States)

    Ryana, Haneet Kour; Srinath, Rashmi; Prakash, Shobha

    2016-06-01

    Intentional replantation is generally contraindicated in periodontally compromised teeth however, there are reports suggesting that it can be a successful treatment alternative for periodontally involved hopeless teeth. Currently there is dearth of evidence regarding the success of this therapy, especially evidence for the effectiveness of autologous platelet rich fibrin is lacking. We present a case report of a 23-year-old male patient with periodontally hopeless left maxillary central incisor having bone loss extending beyond root apex. The tooth was gently extracted and replanted utilizing root conditioning and combined regenerative therapy (Xenograft, PRF and Type I Collagen Membrane). Surgical re-entry at nine months revealed bone formation in the apical third of the tooth. At one year, 87% radiographic bone gain was accomplished. The improvement in the clinical and radiographic parameters reinforced by the re-entry surgery findings strongly suggest that intentional replantation may be a cost-effective substitute to implants and tooth supported prosthesis in situations where conventional periodontal therapy would yield compromised outcomes.

  4. Histological and immunohistochemical analyses of the chronology of healing process after immediate tooth replantation in incisor rat teeth.

    Science.gov (United States)

    Panzarini, Sônia Regina; Okamoto, Roberta; Poi, Wilson Roberto; Sonoda, Celso Koogi; Pedrini, Denise; da Silva, Paula Ervolino; Saito, Celia Tomiko Matida Hamata; Marão, Heloísa Fonseca; Sedlacek, Paulo

    2013-02-01

    Dental tissues have special characteristics, and its regenerative capacity is noteworthy. However, understanding the circumstances that lead to regeneration is challenging. In this study, the chronology of the healing process after immediate replantation of rat incisor teeth was examined by histological and immunohistochemical analyses within a 60-day period. Thirty-six male Wistar rats had their maxillary right incisors extracted and replanted after 15 min in saline storage. The rats were sacrificed immediately 3, 7, 15, 28, and 60 days after replantation. The histological analysis showed rupture of the periodontal ligament and formation of a blood clot, which started being replaced by a connective tissue after 3 days. At 7 days, the gingival mucosa epithelium was reinserted and areas of root resorption could be seen. At 15 days, the periodontal ligament was repaired. At 3 days, the pulp presented an absence of the odontoblast layer, which started being replaced by a connective tissue. This tissue suffered gradual calcification, filling the root canal at 28 and 60 days. The root ends were closed. The immunohistochemical analysis revealed greater expression of OP, OPG, and RANK proteins in the initial periods (0 and 3 days), while TRAP expression predominated at 28 and 60 days (P process, while a predominance of bone resorption and remodeling is observed in the more advanced periods. © 2012 John Wiley & Sons A/S.

  5. Surgical Re-entry of an Intentionally Replanted Periodontally Compromised Tooth Treated with Platelet Rich Fibrin (PRF): Hopeless to Hopeful

    Science.gov (United States)

    Srinath, Rashmi; Prakash, Shobha

    2016-01-01

    Intentional replantation is generally contraindicated in periodontally compromised teeth however, there are reports suggesting that it can be a successful treatment alternative for periodontally involved hopeless teeth. Currently there is dearth of evidence regarding the success of this therapy, especially evidence for the effectiveness of autologous platelet rich fibrin is lacking. We present a case report of a 23-year-old male patient with periodontally hopeless left maxillary central incisor having bone loss extending beyond root apex. The tooth was gently extracted and replanted utilizing root conditioning and combined regenerative therapy (Xenograft, PRF and Type I Collagen Membrane). Surgical re-entry at nine months revealed bone formation in the apical third of the tooth. At one year, 87% radiographic bone gain was accomplished. The improvement in the clinical and radiographic parameters reinforced by the re-entry surgery findings strongly suggest that intentional replantation may be a cost-effective substitute to implants and tooth supported prosthesis in situations where conventional periodontal therapy would yield compromised outcomes. PMID:27504421

  6. Chemical and stable carbon isotopic composition of PM2.5 from on-road vehicle emissions in the PRD region and implication for vehicle emission control policy

    Directory of Open Access Journals (Sweden)

    S. Dai

    2014-11-01

    Full Text Available Vehicle emission is a major source of urban air pollution. In recent decade, the Chinese government has introduced a range of policies to reduce the vehicle emission. In order to understand the chemical characteristics of PM2.5 from on-road vehicle emission in the Pearl River Delta (PRD region and to evaluate the effectiveness of control policies on vehicles emission, the emission factors of PM2.5 mass, elemental carbon (EC, organic carbon (OC, water-soluble organic carbon (WSOC, water-soluble inorganic ions (WSII, metal elements, organic compounds and stable carbon isotopic composition were measured in the Zhujiang Tunnel of Guangzhou, the PRD region of China in 2013. Emission factors of PM2.5 mass, OC, EC, and WSOC were 92.4, 16.7, 16.4, and 1.31 mg vehicle−1 km−1 respectively. Emission factors of WSII were 0.016 (F- ~4.17 (Cl- mg vehicle−1 km−1, totally contributing about 9.8% to the PM2.5 emissions. The sum of 27 measured metal elements accounted for 15.2% of the PM2.5 emissions. Fe was the most abundant metal element, with an emission factor of 3.91 mg vehicle−1 km−1. Emission factors of organic compounds including n-alkanes, PAHs, hopanes, and steranes were 91.9, 5.02, 32.0 and 7.59 μg vehicle−1 km−1, respectively. Stable carbon isotopic composition δ13C value was measured and it was −25.0‰ on average. An isotopic fractionation of 3.2‰ was found during fuel combustion. Compared with a previous study in Zhujiang Tunnel in year 2004, emission factors of PM2.5 mass, EC, OC, WSII except Cl-, and organic compounds decreased by 16.0–93.4%, which could be attributed to emission control policy from 2004 to 2013. However, emission factors of most of the metal elements increased significantly, which could be partially attributed to the changes in motor oil additives and vehicle condition. There are no mandatory national standards to limit metal content from vehicle emission, which should be a concern of the government. A

  7. Déterminants sociaux et économiques de la replantation

    Directory of Open Access Journals (Sweden)

    Ruf François

    2000-03-01

    Full Text Available Sur les bourses européennes, la notion de durabilité des investissements dans les valeurs est explicite « Développement durable rime avec investissement rentable » (La Tribune, 11 mars 2000. La maxime émerge avec le développement des fonds éthiques. Selon leurs promoteurs, plus une société commerciale aura le souci de son environnement, plus elle sera boursièrement performante. D’une certaine façon, ce raisonnement reprend des courants de l’écologie humaine et de l’économie rurale, s’appliquant fort bien aux cultures pérennes. En l’absence de pensions et de retraites, les planteurs voient dans les cultures pérennes un moyen efficace pour accumuler des richesses, épargner, et éventuellement pour les transmettre à la génération suivante [1, 2]. Les cultures pérennes représentent bien un patrimoine, et leur propriétaire est à la fois un entrepreneur qui investit et un épargnant soucieux de la valeur de son patrimoine, donc de l’environnement garantissant sa durabilité. Cette notion de durabilité peut signifier une stratégie de prolongement de vie économique de l’actif épargné, la plantation, mais peut aussi passer par des stratégies de vente, de rachat, de reconversion, replantation, diversification. Pour un planteur, tout à la fois chef de famille, entrepreneur, épargnant et consommateur, la notion de durabilité s’applique d’abord à celle des revenus disponibles pour la famille. Par rapport à un objectif de durabilité des revenus, comment, pourquoi et quand un planteur prend-il la décision de replanter ? Nous essayerons ici de répondre à cette question sous forme de réflexion et d’exemples pris dans différents pays pour diverses cultures pérennes.

  8. The scattering polarization of the Ly-alpha lines of H I and He II taking into account PRD and J-state interference effects

    CERN Document Server

    Belluzzi, Luca; Stepan, Jiri

    2012-01-01

    Recent theoretical investigations have pointed out that the cores of the Ly-alpha lines of H I and He II should show measurable scattering polarization signals when observing the solar disk, and that the magnetic sensitivity, through the Hanle effect, of such linear polarization signals is suitable for exploring the magnetism of the solar transition region. Such investigations were carried out in the limit of complete frequency redistribution (CRD) and neglecting quantum interference between the two upper J-levels of each line. Here we relax both approximations and show that the joint action of partial frequency redistribution (PRD) and J-state interference produces much more complex fractional linear polarization (Q/I) profiles, with large amplitudes in their wings. Such wing polarization signals turn out to be very sensitive to the temperature structure of the atmospheric model, so that they can be exploited for constraining the thermal properties of the solar chromosphere. Finally, we show that the approxi...

  9. El Partido (partido de la Revolución ¿Democrática? La dominación carismática en el PRD

    Directory of Open Access Journals (Sweden)

    Oscar Rivera Serafín

    2011-01-01

    Full Text Available El presente artículo analizará uno de los partidos políticos referentes en el sistema político mexicano: el Partido de la Revolución Democrática (PRD. El argumento a desarrollar es que dadas las características originarias de tal partido, la cohesión en los grupos políticos que lo componen sólo es alcanzada a través de un liderazgo carismático. Naturalmente, tal dependencia somete a dichos grupos a la inestabilidad inherente al ejercicio de la dominación carismática, por lo que sólo la aparición de un nuevo liderazgo les permite retomar la cohesión cuando el anterior declina.

  10. El Partido (partido) de la Revolución ¿Democrática? La dominación carismática en el PRD

    OpenAIRE

    Oscar Rivera Serafín

    2011-01-01

    El presente artículo analizará uno de los partidos políticos referentes en el sistema político mexicano: el Partido de la Revolución Democrática (PRD). El argumento a desarrollar es que dadas las características originarias de tal partido, la cohesión en los grupos políticos que lo componen sólo es alcanzada a través de un liderazgo carismático. Naturalmente, tal dependencia somete a dichos grupos a la inestabilidad inherente al ejercicio de la dominación carismática, por lo que sólo la apari...

  11. Root removal to improve disease management in replanted Washington red raspberry fields

    Science.gov (United States)

    Washington leads the nation in the production of red raspberries for processing. Soilborne pathogens are a production constraint in this $61 million industry with growers relying on preplant soil fumigation for their management. However, current fumigation methods can be ineffective, leading to repl...

  12. Process analysis and sensitivity study of regional ozone formation over the Pearl River Delta, China, during the PRIDE-PRD2004 campaign using the Community Multiscale Air Quality modeling system

    Directory of Open Access Journals (Sweden)

    X. Wang

    2010-05-01

    Full Text Available In this study, the Community Multiscale Air Quality (CMAQ modeling system is used to simulate the ozone (O3 episodes during the Program of Regional Integrated Experiments of Air Quality over the Pearl River Delta, China, in October 2004 (PRIDE-PRD2004. The simulation suggests that O3 pollution is a regional phenomenon in the Pearl River Delta (PRD. Elevated O3 levels often occurred in the southwestern inland PRD, Pearl River estuary (PRE, and southern coastal areas during the 1-month field campaign. Three evolution patterns of simulated surface O3 are summarized based on different near-ground flow conditions. More than 75% of days featured interactions between weak synoptic forcing and local sea-land circulation. Integrated process rate (IPR analysis shows that photochemical production is a dominant contributor to O3 enhancement from 09:00 to 15:00 local standard time in the atmospheric boundary layer over most areas with elevated O3 occurrence in the mid-afternoon. The simulated ozone production efficiency is 2–8 O3 molecules per NOx molecule oxidized in areas with high O3 chemical production. Precursors of O3 originating from different source regions in the central PRD are mixed during the course of transport to downwind rural areas during nighttime and early morning, where they then contribute to the daytime O3 photochemical production. The sea-land circulation plays an important role on the regional O3 formation and distribution over PRD. Sensitivity studies suggest that O3 formation is volatile-organic-compound-limited in the central inland PRD, PRE, and surrounding coastal areas with less chemical aging (NOx/NOy>0.6, but is NOx-limited in the rural southwestern PRD with aged air (NOx/NOy<0.3.

  13. [Periodontal disease in pediatric rheumatic diseases].

    Science.gov (United States)

    Fabri, Gisele M C; Savioli, Cynthia; Siqueira, José T; Campos, Lucia M; Bonfá, Eloisa; Silva, Clovis A

    2014-01-01

    Gingivitis and periodontitis are immunoinflammatory periodontal diseases characterized by chronic localized infections usually associated with insidious inflammation This narrative review discusses periodontal diseases and mechanisms influencing the immune response and autoimmunity in pediatric rheumatic diseases (PRD), particularly juvenile idiopathic arthritis (JIA), childhood-onset systemic lupus erythematosus (C-SLE) and juvenile dermatomyositis (JDM). Gingivitis was more frequently observed in these diseases compared to health controls, whereas periodontitis was a rare finding. In JIA patients, gingivitis and periodontitis were related to mechanical factors, chronic arthritis with functional disability, dysregulation of the immunoinflammatory response, diet and drugs, mainly corticosteroids and cyclosporine. In C-SLE, gingivitis was associated with longer disease period, high doses of corticosteroids, B-cell hyperactivation and immunoglobulin G elevation. There are scarce data on periodontal diseases in JDM population, and a unique gingival pattern, characterized by gingival erythema, capillary dilation and bush-loop formation, was observed in active patients. In conclusion, gingivitis was the most common periodontal disease in PRD. The observed association with disease activity reinforces the need for future studies to determine if resolution of this complication will influence disease course or severity.

  14. Clinical observation on 52 cases of traumatic dislocation teeth replantation%外伤脱位牙再植术52例临床疗效观察

    Institute of Scientific and Technical Information of China (English)

    杨淑英

    2014-01-01

    Objective:To observe the clinical curative effect of traumatic dislocation teeth replantation.Methods:52 patients(83 teeth) with traumatic complete dislocation teeth who were taken replantation since 2010 were selected.They were followed up after replantation,then we observed the effect of treatment.Results:There were 58 teeth completely successful after replantation(69.88% );17 teeth were basic successful(20.48% );8 teeth were failure(9.64% ).54 teeth were periodontal healing(65.06%);22 teeth were bone healing(26.51%) and 7 teeth were fibrous healing(8.43%).Conclusion:If you can correct save luxated tooth and timely replantated when the complete dislocation teeth occurred,the success rate of replantation can improve effectively.%目的:观察外伤脱位牙再植术的临床疗效。方法:2010年以来收治外伤导致牙完全性脱位后再植患者52例(83颗牙),再植术后进行随访,观察治疗效果。结果:再植术后,完全成功58颗(69.88%),基本成功17颗(20.48%),失败8颗(9.64%)。牙周膜愈合54颗(65.06%),骨性愈合22颗(26.51%),纤维性愈合7颗(8.43%)。结论:发生完全性牙脱位后,正确地保存脱位牙,并及时就诊再植能够有效地提高再植成功率。

  15. Influence of enamel matrix derivative (Emdogain) and sodium fluoride on the healing process in delayed tooth replantation: histologic and histometric analysis in rats.

    Science.gov (United States)

    Poi, Wilson Roberto; Carvalho, Roberta Martinelli; Panzarini, Sônia Regina; Sonoda, Celso Koogi; Manfrin, Thais Mara; Rodrigues, Thais da Silveira

    2007-02-01

    Although it has already been shown that enamel matrix derivative (Emdogain) promotes periodontal regeneration in the treatment of intrabony periodontal defects, there is little information concerning its regenerative capacity in cases of delayed tooth replantation. To evaluate the alterations in the periodontal healing of replanted teeth after use of Emdogain, the central incisors of 24 Wistar rats (Rattus norvegicus albinus) were extracted and left on the bench for 6 h. Thereafter, the dental papilla and the enamel organ of each tooth were sectioned for pulp removal by a retrograde way and the canal was irrigated with 1% sodium hypochlorite. The teeth were assigned to two groups: in group I, root surface was treated with 1% sodium hypochlorite for 10 min (changing the solution every 5 min), rinsed with saline for 10 min and immersed in 2% acidulated-phosphate sodium fluoride for 10 min; in group II, root surfaces were treated in the same way as described above, except for the application of Emdogain instead of sodium fluoride. The teeth were filled with calcium hydroxide (in group II right before Emdogain was applied) and replanted. All animals received antibiotic therapy. The rats were killed by anesthetic overdose 10 and 60 days after replantation. The pieces containing the replanted teeth were removed, fixated, decalcified and paraffin-embedded. Semi-serial 6-microm-thick sections were obtained and stained with hematoxylin and eosin for histologic and histometric analyses. The use of 2% acidulated-phosphate sodium fluoride provided more areas of replacement resorption. The use of Emdogain resulted in more areas of ankylosis and was therefore not able to avoid dentoalveolar ankylosis. It may be concluded that neither 2% acidulated-phosphate sodium fluoride nor Emdogain were able to prevent root resorption in delayed tooth replantation in rats.

  16. A study of the interleukin-1 gene cluster polymorphisms and inflammatory external root resorption in replanted permanent teeth.

    Science.gov (United States)

    Bastos, J V; Côrtes, M I S; Silva, J F C; Goulart, E M A; Colosimo, E A; Gomez, R S; Dutra, W O

    2015-09-01

    To investigate whether single nucleotide polymorphisms (SNPs) within the interleukin-1 gene cluster (IL1) are associated with the occurrence and severity of inflammatory external root resorption (IERR) after replantation of avulsed permanent teeth. Indexes of IERR were radiographically assessed in 182 mature replanted permanent teeth from 146 patients at the onset of endodontic therapy. DNA was extracted from buccal mucosa cells and genotyped using TaqMan probes-based assays for the SNPs IL1A -889C/T (rs 180058), IL1B +3954C/T (rs1143634) and IL1RN +2018C/T (rs419598). Teeth were grouped into two categories: IERR absent to mild (indexes ≤ 4) and moderate to severe IERR (indexes > 4). Genetic variations in the IL1 gene cluster were tested for their effect on the occurrence and extension of IERR using the GEE model (generalized estimation equation). Patient's age at the moment of injury, timing of pulpectomy, extra-alveolar period and storage condition of the avulsed teeth was included as possible confounders. No association was found between SNPs IL1A -889C/T, IL1B +3954C/T (rs1143634) and IL1RN +2018C/T (rs419598) and IERR indexes. Timing of pulpectomy (OR 3.5 IC 95% 2.0-6.2 P < 0.001) and patient's age at the moment of trauma (OR 0.29 IC 95% 0.12-0.67 P = 0.004) significantly affected the risk of developing severe IERR. While timing of pulpectomy and patient's age at the moment of trauma were confirmed as important risk factors, SNPs within the IL1 gene cluster did not affect the susceptibility for IERR after replantation of permanent teeth. © 2014 International Endodontic Journal. Published by John Wiley & Sons Ltd.

  17. The effect of wind induced bottom shear stress and salinity on Zostera noltii replanting in a Mediterranean coastal lagoon

    Science.gov (United States)

    Alekseenko, E.; Roux, B.; Fougere, D.; Chen, P. G.

    2017-03-01

    The paper concerns the wind influence on bottom shear stress and salinity levels in a Mediterranean semi-enclosed coastal lagoon (Etang de Berre), with respect to a replanting program of Zostera noltii. The MARS3D numerical model is used to analyze the 3D current, salinity and temperature distribution induced by three meteorological, oceanic and anthropogenic forcings in this lagoon. The numerical model has been carefully validated by comparison with daily observations of the vertical salinity and temperature profiles at three mooring stations, for one year. Then, two modelling scenarios are considered. The first scenario (scen.#1), starting with a homogeneous salinity of S = 20 PSU and without wind forcing, studies a stratification process under the influence of a periodic seawater inflow and a strong freshwater inflow from a hydropower plant (250 m3/s). Then, in the second scenario (scen.#2), we study how a strong wind of 80 km/h can mix the haline stratification obtained at the end of scen.#1. The most interesting results concern four nearshore replanting areas; two are situated on the eastern side of EB and two on the western side. The results of scen.#2 show that all these areas are subject to a downwind coastal jet. Concerning bottom salinity, the destratification process is very beneficial; it always remains greater than 12 PSU for a N-NW wind of 80 km/h and an hydropower runoff of 250 m3/s. Special attention is devoted to the bottom shear stress (BSS) for different values of the bottom roughness parameter (for gravels, sands and silts), and to the bottom salinity. Concerning BSS, it presents a maximum near the shoreline and decreases along transects perpendicular to the shoreline. There exists a zone, parallel to the shoreline, where BSS presents a minimum (close to zero). When comparing the BSS value at the four replanting areas with the critical value, BSScr, at which the sediment mobility would occur, we see that for the smaller roughness values (ranging

  18. Kidney diseases in Roma and non-Roma children from eastern Slovakia: are Roma children more at risk?

    Science.gov (United States)

    Kolvek, Gabriel; Podracka, Ludmila; Rosenberger, Jaroslav; Stewart, Roy E; van Dijk, Jitse P; Reijneveld, Sijmen A

    2014-12-01

    To compare the occurence of primary renal diseases (PRD) in Roma and non-Roma children. Data on all outpatients (n = 921) from a tertiary pediatric nephrology centre (Roma and non-Roma children. The proportion of Roma among patients was relatively small regarding early signs like proteinuria but large regarding PRD with gross clinically apparent symptoms (e.g. Alport syndrome, p Roma children in outpatients with kidney problems is smaller than the estimated proportion of Roma in all children in Slovakia, in particular for early signs, but not for major renal diseases.

  19. The biomechanical role of periodontal ligament in bonded and replanted vertically fractured teeth under cyclic biting forces

    Institute of Scientific and Technical Information of China (English)

    Ya-Nan Zhu; Wei-Dong Yang; Paul V Abbott; Nicolas Martin; Wen-Jia Wei; Jing-Jing Li; Zhi Chen; Wen-Mei Wang

    2015-01-01

    After teeth are replanted, there are two possible healing responses:periodontal ligament healing or ankylosis with subsequent replacement resorption. The purpose of this study was to compare the fatigue resistance of vertically fractured teeth after bonding the fragments under conditions simulating both healing modes. Thirty-two human premolars were vertically fractured and the fragments were bonded together with Super-Bond C&B. They were then randomly distributed into four groups (BP, CP, CA, BA). The BP and CP groups were used to investigate the periodontal ligament healing mode whilst the BA and CA groups simulated ankylosis. All teeth had root canal treatment performed. Metal crowns were constructed for the CP and CA groups. The BP and BA groups only had composite resin restorations in the access cavities. All specimens were subjected to a 260 N load at 4 Hz until failure of the bond or until 23106 cycles had been reached if no fracture occurred. Cracks were detected by stereomicroscope imaging and also assessed via dye penetration tests. Finally, interfaces of the resin luting agent were examined by scanning electron microscope. The results confirmed that the fatigue resistance was higher in the groups with simulated periodontal ligament healing. Periodontal reattachment showed important biomechanical role in bonded and replanted vertically fractured teeth.

  20. Multidisciplinary approach in the immediate replantation of a maxillary central incisor - A six and a half year follow-up

    Directory of Open Access Journals (Sweden)

    Cristina Braga Xavier

    2015-01-01

    Full Text Available This report proposes a discussion of the various peculiarities of a tooth 21 replantation in a 9-year-old patient and describes different treatment facets and a 6-year follow-up of the case. The splint was maintained for a 3-month period. After a 1΍ year therapy with calcium hydroxide to control inflammatory resorption, the final canal obturation was performed 18 months after trauma with mineral trioxide aggregate. Two years after replantation, the orthodontic treatment had been initiated and 5 years after avulsion, whitening of tooth 21 was also done. Clinical and radiographic follow-up at regular intervals revealed that the treated tooth was still functional, showing normal mobility, resorption stabilization, and normal appearance of the bone tissue and lamina dura, testifying the treatment has been so far successful. The possibility of submitting avulsed teeth to other dental treatments once, there is close professional monitoring by controlling the risks and benefits of each therapy, as well as the patient′s cooperation, extra-oral time, and storage media for transport to the dentist among other details is emphasized.

  1. [The dynamics of morphofunctional changes in the microcirculation of the pelvic extremity after modeling the chief stages of its replantation].

    Science.gov (United States)

    Simagin, E I; Dimitrov, N G; Kiprenskiĭ, Iu V; Solntsev, A B

    1975-06-01

    Under study was the effect of autotransplantation in its "pure form" upon the morpho-functional reconstruction and structural mechanisms of adaptation of the blood and lymphatic links of the microcirculatory bed of extremities during early postoperation period up to 10 days. The pathophysiological state of the extremity sufficiently close to its autotransplantation was obtained by means of circular transection of soft tissues of the medial third of the femur together with the nerves and deep collecting lymphatic vessels. It was found that after modeling the main stages of replantation in the fascia and periosteum of the operated extremity there developed a spasm of the arteriolar link and dilatation of the venular and lymphatic links of the microcirculatory bed. The areas of leukocytic infiltration with the phenomena of diapedesis and microhemorrhages were revealed along the course of postcapillaries and venules in the paravasal connective tissue. The amount of functioning arteriole-venular anastomoses was increased. Against the background of pronounced oedema of soft tissues of the operated extremity the venous pressure increased and the rate of the capillary bloodflow in the skin and muscles decreased. The above changes tend to be reduced by the 10th day after modelling the main stages of replantation of the extremity.

  2. Treatment of replacement resorption by intentional replantation, resection of the ankylosed sites, and Emdogain--results of a 6-year survey.

    Science.gov (United States)

    Filippi, Andreas; Pohl, Yango; von Arx, Thomas

    2006-12-01

    The present clinical study investigated the outcome of intentional replantation using resection of the ankylosed sites of the root, extraoral endodontic treatment using titanium posts and Emdogain for periodontal healing following trauma-related ankylosis. During an evaluation period of 6 years, 16 ankylosed teeth affected by replacement resorption were treated as described. Evaluation parameters before treatment and during the follow-up period included Periotest scores, percussion sound and periapical radiographs. All findings were compared to those of the adjacent teeth. In a second accident, one tooth was lost after 7 months and was excluded as a dropout. Ankylosis did not recur in seven replanted teeth, which were observed for an average of 52.3 months (range: 24-68 months). Ankylosis recurred in eight teeth after an average period of 12 months (range: 4-26 months). An infraocclusion, normal or only slightly reduced Periotest scores and normal percussion sound were preoperatively found in six of seven successfully replanted teeth, which corresponded to a relatively small area of ankylosis. The majority of the teeth showing recurrent ankylosis preoperatively presented with normal position, negative Periotest scores and a high percussion sound which corresponded to an extended area of ankylosis. Statistically significant relationship between preoperative findings and the treatment outcome (P = 0.031) have become apparent. The results indicate that the treatment of minor areas of ankylosis by intentional replantation, resection of the ankylosed sites and Emdogain appeared to prevent or delay the recurrence of ankylosis in 7 of 15 teeth.

  3. Soil pH in fruit trees in relation to specific apple replant disorder (SARD). II. The first five years at Wageningen research plot

    NARCIS (Netherlands)

    Jonkers, H.; Hoestra, H.; Borsboom, O.; Pouwer, A.

    1980-01-01

    Field plots were established with 4 target pH values, viz. 4, 5, 6 and 7, to study the effect of pH on specific apple replant disorder (SARD). The target pH levels were not stable and frequently showed fluctuations. Although no significant differences have been found on tree performance, the develop

  4. 恒牙全脱位再植的研究现状%Present Studies of Replantation of Avulsed Permanent Teeth

    Institute of Scientific and Technical Information of China (English)

    钱瀚宇; 丁允鹏

    2015-01-01

    Permanent teeth are prone to avulsion by trauma.Replantation is the preferred treatment for avulsed perma-nent teeth, and the ideal prognosis of replantation is to achieve functional healing of periodontal ligament. If the avulsed teeth are immature, revascularization of the dental pulp is expected. The duration of extra-alveolar time, preservation of the root and storage media of the tooth, all of which determine the prognosis for dental replantation, but the current prognosis is not satisfactory. Present studies of replantation of avulsed permanent teeth were reviewed in the present paper.%恒牙外伤常导致牙齿全脱位,再植术是恒牙全脱位的首选治疗方法. 理想的预后是实现牙周功能性愈合,若牙根尖未完全封闭,尚有牙髓再生的可能. 恒牙再植术的预后与很多因素有关,如牙齿脱离牙槽窝的时间、牙根的保存以及牙齿的储存介质等,目前临床治疗效果尚不理想. 本文就恒牙全脱位再植的研究现状作一综述.

  5. Assessment of heavy metals/metalloid (As, Pb, Cd, Ni, Zn, Cr, Cu, Mn) concentrations in edible fish species tissue in the Pearl River Delta (PRD), China.

    Science.gov (United States)

    Leung, H M; Leung, A O W; Wang, H S; Ma, K K; Liang, Y; Ho, K C; Cheung, K C; Tohidi, F; Yung, K K L

    2014-01-15

    The major aim of this study was to investigate heavy metal content of edible fish in the PRD. Eleven species of fish (consisting of 711 individuals) [catfish (Clarias fuscus), tilapia (Oreochromis mossambicus), grass carp (Ctenopharyngodon idellus), bighead carp (Aristichthys nobilis), mandarin fish (Siniperca kneri), snakehead (Channa asiatiea), black bass (Micropterus salmoides), mangrove snapper (Lutjanus griseus), star snapper (Lutjanu stellatus), snubnose pompano (Trachinotus blochii) and orange-spotted grouper (Epinephelus coioides)] were collected for the analyses of heavy metals. Overall concentrations (mg/kg, ww) in the fish muscles were: As (0.03-1.53), Pb (0.03-8.62), Cd (0.02-0.06), Ni (0.44-9.75), Zn (15.7-29.5), Cr (0.22-0.65), Cu (0.79-2.26), Mn (0.82-6.91). Significant level of Pb were found in tilapia at all locations. It is recommended that heavy metal concentrations in different fish species must be determined on a regular basis in the future so as to reduce human health risks from acute and chronic food intoxication.

  6. An isoform of Taiman that contains a PRD-repeat motif is indispensable for transducing the vitellogenic juvenile hormone signal in Locusta migratoria.

    Science.gov (United States)

    Wang, Zhiming; Yang, Libin; Song, Jiasheng; Kang, Le; Zhou, Shutang

    2017-03-01

    Taiman (Tai) has been recently identified as the dimerizing partner of juvenile hormone (JH) receptor, Methoprene-tolerant (Met). However, the role of Tai isoforms in transducing vitellogenic signal of JH has not been determined. In this study, we show that the migratory locust Locusta migratoria has two Tai isoforms, which differ in an INDEL-1 domain with the PRD-repeat motif rich in histidine and proline at the C-terminus. Tai-A with the INDEL-1 is expressed at levels about 50-fold higher than Tai-B without the INDEL-1 in the fat body of vitellogenic adult females. Knockdown of Tai-A but not Tai-B results in a substantial reduction of vitellogenin expression in the fat body accompanied by the arrest of ovarian development and oocyte maturation, similar to that caused by depletion of both Tai isoforms. Either Tai-A or Tai-B combined with Met can induce target gene transcription in response to JH, but Tai-A appears to mediate a significantly higher transactivation. Our data suggest that the INDEL-1 domain plays a critical role in Tai function during reproduction as Tai-A appears be more active than Tai-B in transducing the vitellogenic JH signal in L. migratoria.

  7. La replantation digitale, résultats et complications: étude d’une série de 18 cas

    Science.gov (United States)

    Idrissi, Mohammed El; Elibrahimi, Abdelhalim; Shimi, Mohammed; Elmrini, Abdelmajid

    2016-01-01

    Les amputations digitales sont des lésions fréquentes, la majorité étant provoquée par des accidents de travail. Les techniques microchirurgicales représentent une alternative pour réparer ces amputations. L'objectif de ce travail est de rapporter notre expérience dans la replantation digitale à travers l'étude de 18 cas. Nous avons mené une étude rétrospective, étalée entre Juin 2013 et Janvier 2015, incluant 14 patients présentant une amputation totale ou subtotale des doigts. Nous avons inclus dans notre série toutes les replantations unidigitales et multidigitales réalisées en aval de l'insertion distale du tendon fléchisseur superficiel ainsi que les replantations digitales réalisées en amont de l'insertion distale du tendon fléchisseur superficiel. Nous avons opéré ces patients selon le procédé classique de réimplantation digitale. Cinq replantations ont été secondairement régularisées. Parmi les 18 replantations, huit replantions digitales ont favorablement évolué puisque la replantation a permis de restituer un secteur complet de mobilité passive et active du doigt opéré sans chirurgie de reprise et sans complication secondaire précoce et tardive. Dans notre étude nous avons noté des résultats satisfaisants, malgré les conditions difficiles notamment le conditionnement initial du doigt amputé, et le délai de prise en charge retardé. Le développement et la maîtrise de la microchirurgie a permis de changer le pronostic de ces amputations à retentissement fonctionnel et psychologique difficile, les résultats de notre série sont encourageants pour a mise en place d'un service SOS main au Maroc. PMID:27795781

  8. Replantation methods of mini tissue mass of amputated finger%手指小组织块离断再植的临床体会

    Institute of Scientific and Technical Information of China (English)

    刘育杰; 丁小珩; 焦鸿生; 方光荣; 张宏勋; 屈志刚; 姜凯

    2011-01-01

    目的 探讨手指小组织块离断后再植的手术方法和治疗效果.方法 对手指不同部位小组织块离断20例26指,采用血管直接吻合、桥接吻合、动脉静脉化、静脉动脉化等多种血运重建方式进行原位再植.结果 再植组织块完全成活25指,部分坏死1指,经过换药后痊愈.术后随访6~12个月,再植指屈伸功能良好,外形满意.结论 对手指不同部位小组织块离断,采用显微外科重建技术原位再植,能获得较好的临床疗效.%Objective To investigate the replantation methods and outcomes of mini tissue mass of amputated finger. Methods Twenty-six fingers of 20 patients were replanted with multiple vessel anastomosis methods to restore blood supply.The methods include vascular anastomosis,vascular bridge,arteriovenolization,veno-arteriolization,et al. Results Twenty-five replanted tissues were survived completely.Partly necrosis occur in 1 case,and rehabilitation by change dressings.The patients were follow up from 6 to 12 months.The contour and function of the replantation fingers recovered satisfactory. Conclusion By using the rational anastomosis according to the traumatic condition,it could be obtain good outcome of mini tissue mass replantation

  9. Problèmes entomologiques en replantation des palmeraies et des cocoteraies

    Directory of Open Access Journals (Sweden)

    Mariau Dominique

    2000-03-01

    Full Text Available C’est aux alentours de la vingt-cinquième année que l’on envisage de replanter une palmeraie. C’est en effet vers cet âge que commencent à se poser des problèmes de récolte en raison de la taille des palmiers. En un quart de siècle, l’amélioration génétique aura suffisamment fait de progrès pour escompter un gain de production de l’ordre de 20%. Enfin, dans certaines situations, plusieurs maladies ont pu affecter les vieilles palmeraies. Avec de 15 à 25% d’arbres manquants, principalement lorsque ceux-ci se présentent sous la forme de taches, une diminution de la production se fait nettement sentir. Cela peut, par exemple, être le cas avec les maladies de la fusariose en Afrique de l’Ouest, lorsque la palmeraie n’a pas été plantée avec du matériel végétal tolérant, ou du ganoderma en Malaisie. Le renouvellement des cocoteraies se fait avec un espace de temps beaucoup plus long. En effet, la récolte des noix peut se faire au sol et la hauteur des cocotiers n’est donc pas un facteur limitant. Par ailleurs, la majorité des cocoteraies étant sous la forme de petites plantations villageoises, les agriculteurs rechignent toujours à abattre leurs cocotiers, même si des semences potentiellement plus productives leurs sont proposées. Ce sont les raisons pour lesquelles les cocoteraies de 50 ans et plus représentent la règle. L’abattage d’une plantation de palmiers à huile ou de cocotiers constitue naturellement un changement brutal de l’environnement, ce qui a des conséquences importantes notamment sur l’entomofaune, parmi laquelle des ravageurs majeurs ainsi que leurs ennemis naturels.

  10. [Optimising care structures for severe hand trauma and replantation and chances of launching a national network].

    Science.gov (United States)

    Haas, E M; Volkmer, E; Holzbach, T; Wallmichrath, J; Engelhardt, T O; Giunta, R E

    2013-12-01

    Severe hand traumata have a significant impact on our health system and on insurance companies, respectively. It is estimated that 33% of all occupational injuries and 9% of all invalidity pensions are due to severe hand trauma. Unfortunately, these high numbers are not only due to the severity of the trauma but to organisational deficiencies. Usually, the patient is treated at the general surgical emergency in the first place and only then forwarded to a microsurgeon. This redirection increases the time that is required for the patient to finally arrive at an expert for hand surgery. On the one hand, this problem can be explained by the population's lack of awareness for distinguished experts for hand and microsurgery, on the other hand, the emergency network, or emergency doctors in particular are not well informed about where to take a patient with a severe hand trauma - clearly a problem of communication between the hospitals and the ambulance. It is possible to tackle this problem, but put participating hand trauma centres have to work hand in hand as a network and thus exploit synergy effects. The French system "FESUM" is a good example for such a network and even comprises centres in Belgium and Switzerland. To improve the treatment of severe hand trauma, a similar alliance was initiated in Germany just recently. The pilot project "Hand Trauma Alliance" (www.handverletzung.com) was started in April 2013 and currently comprises two hospitals within the region of upper Bavaria. The network provides hand trauma replantation service on a 24/7 basis and aims at shortening the way from the accident site to the fully qualified hand surgeon, to improve the therapy of severe hand injuries and to optimise acute patient care in general. In order to further increase the alliance's impact it is intended to extend the project's scope from regional to national coverage - nevertheless, such an endeavour can only be done in collaboration with the German Society for Hand

  11. Analysis on Micro-structural Characteristics of Soft Soil in PRD during Consolidation Test%珠三角软土微观结构试验分析

    Institute of Scientific and Technical Information of China (English)

    周晖; 房营光; 李勇

    2009-01-01

    土的微结构对土的力学行为机制起着至关重要的作用,对珠三角典型的软土进行单向压缩试验,利用环境扫描电子显微镜(ESEM)所得的照片研究软土在不同固结压力条件下的微结构大小、形状、定向性等微结构参数,分析其变化规律.研究表明:随着固结压力的增加,结构单元体不断变大,集合体的形状在垂直于压力的方向变长,结构单元体的定向性有所提高但不显著;孔隙分布分维呈下降趋势并逐步稳定.%Structural properties of soil had a great impact on mechanical properties of the soil. Uniaxial compression test was completed for soft soil of PRD.The use of environmental scanning electron microscope (ESEM) photos of soft soil in different pressure,to study the different micro-structural parameters including the size, shape, orientation of pores and structural units,to analyze the changes in the rules. Studies show that: with the increasing consolidational pressure, the structural units are biger constantly and the shape of aggregates in the perpendicular direction to the pressure is longer, the orientation of structural units is increased, but not significantly. Distribution dimensions of pores decline with the increasing consolidation pressure and trend to become stable.

  12. The critical apical diameter to obtain regeneration of the pulp tissue after tooth transplantation, replantation, or regenerative endodontic treatment.

    Science.gov (United States)

    Laureys, Wim G M; Cuvelier, Claude A; Dermaut, Luc R; De Pauw, Guy A M

    2013-06-01

    Regeneration of pulp-like tissue in the pulp chamber after tooth transplantation, replantation, or in regenerative endodontic treatment is only possible if the apical foramen is open. According to the literature, the success of regeneration decreases considerably if the foramen is smaller than 1 mm when measured on radiographs. The aim of this study was to study histologically the relation between the width of the apical foramen and regeneration of tissue in the pulp chamber after autotransplantation. Fifteen single-rooted mature teeth of 3 adult beagle dogs were used. All experimental teeth were extracted and underwent apicoectomy. The teeth were photographed from the apical side, and the width of the foramen was calculated. The foramen width ranged from 0.24-1.09 mm. All teeth were replanted in infraocclusion. The observation period was 90 days after transplantation. The 10 teeth with the smallest apical diameter, ranging between 0.24 and 0.53 mm, showed vital tissue in at least one third of the pulp chamber. The 6 most successful teeth showing vital tissue in the entire pulp chamber had an apical diameter between 0.32 and 0.65 mm, and 80% of the experimental teeth with a diameter varying between 1.09 and 0.31 mm showed vital tissue in at least one third of the pulp chamber 90 days after transplantation. The size of the apical foramen seems not to be the all decisive factor for successful revascularization and ingrowth of new tissue after transplantation. The minimum width of the apical foramen has not been determined, but a size smaller than 1 mm does not prevent revascularization and ingrowth of vital tissue. In this animal study an apical foramen of 0.32 mm did not prevent ingrowth of new tissue in two-thirds of the pulp chamber 90 days after transplantation. Copyright © 2013 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  13. 石灰氮在草莓重茬生产中的应用%The Application of CaCN2 in Replanted Strawberry Production

    Institute of Scientific and Technical Information of China (English)

    张辉明; 姜永平

    2011-01-01

    The status of replanted strawberry production and the physical and chemical properties of CaCN2 were introduced; The mechanism and efficiency conditions of CaCN2 in replanted strawberry production were elucidated; And the application of CaCN2 in solar disinfection was introduced emphatically.%在简要介绍草莓重茬生产现状、石灰氮的理化性质、石灰氮在草莓重茬生产中的作用机理和作用条件的基础上,重点介绍了利用石灰氮—太阳能消毒的技术.

  14. Replantation of avulsed permanent teeth:an analysis of 32 cases%外伤脱位牙再植后的临床疗效分析

    Institute of Scientific and Technical Information of China (English)

    张月云; 徐龙博

    2011-01-01

    AIM: To analyze the factors influencing the effects of tooth replantation of avulsed permanent teeth.METHODS : Twenty-six children with 32 avulsed permantent teeth were enrolled in this study.The avulsed permantent teeth were replantated in the Department of Pediatric Dentistry, Jining Stomatology Hospital, in the years between 2004 and 2008.The patients were followed up regularly for 2 to 3 years.RESULTS : During the follow-up period, periodontal ligament healing was observed in 4/32, replacement resorption in 23/32, inflammatory resorption in 3/32 and odontoptosis in 2/32 teeth.The success rate of replatation was 84.37%.CONCLUSION: The replantation of young permanent teeth showed a higher success rate.The success of replantation was related to ex vivo time,storage medium and root development stage of the avulsed teeth.%目的:研究探讨影响再植牙临床疗效的相关因素.方法:对2004-2008到我院儿童牙病科就诊的26例8~14岁患儿32个外伤牙进行常规再植,术后定期复查,观察时间2~3年.结果:观察期内,32个外伤恒牙中牙周膜愈合4个,替代性吸收23个,炎症性吸收3个,松动脱落2个.成功率为84.37%.结论:年轻恒牙再植后的成功率较高,但与脱位牙离体时间、保存方式及牙根的发育程度等因素有密切关系.

  15. 重茬胁迫下苹果不同砧木幼苗生长及根系吸收的差异%Differences of growth and root absorption of different apple rootstock seedlings in replant stress

    Institute of Scientific and Technical Information of China (English)

    郭小静; 韩甜甜; 王荣; 张贞; 盖瑞; 毛志泉; 陈学森; 吴树敬; 沈向

    2015-01-01

    [Objective] Selecting appropriate rootstocks is one of the most effective methods of preventing apple from replant disease. In order to provide theoretic foundation for screening of anti-replant rootstock materials and breeding anti-replant rootstock varieties, differences of growth and root absorption of three apple rootstock seedlings were compared, and absorption of potassium and calcium ions under the replant stress was discussed in this study.[Methods] One-year-old seedlings of Malus hupehensis Rehd, Malus sieversii( Ledeb. ) Roem and Malus prunifolia ( Willd. ) Borkh were used as the materials, and 0-40 cm rhizosphere soil of 20 years’ orchard which‘Fuji’ apple on M . robusta stock located in Tai’an city was used as matrix. The seedlings were divided into two parts, some of the seedlings were supplied to determine the flow velocity of rhizosphere K+ and Ca2+ under the replant stress by Non-invasive Micro-test Technique on April 25 , 2012 , other seedlings were transplanted into pots of 25 cm wide and 30 cm deep. The height, stem diameter, chlorophyll content and photosynthetic rate of the seedlings were investigated from July to September. The root structure was scanned and dry weight and fresh weight of roots, branches and leaves were measured respectively after the growing season. [Results]The aboveground growth of the three rootstocks is suppressed in different levels under the replant stress. The heights of M. hupehensis have no significant differences before and after the replant stress, while the heights of the other two rootstocks are significantly decreased. The photosynthetic rates have no significant decreases except M. Sieversii. The chlorophyll contents of three rootstocks are significantly decreased and there are no obviously changes in stem diameter. The dry matter of M. sieversii seedlings is significantly decreased under the replant stress, while the root-shoot ratio is increased. Root biomass amounts of the three rootstocks are

  16. Atmospheric hydrogen peroxide and organic hydroperoxides during PRIDE-PRD'06, China: their concentration, formation mechanism and contribution to secondary aerosols

    Directory of Open Access Journals (Sweden)

    W. Hua

    2008-11-01

    Full Text Available Atmospheric hydrogen peroxide (H2O2 and organic hydroperoxides were measured from 18 to 30 July in 2006 during the PRIDE-PRD'06 campaign at Backgarden, a rural site located 48 km north of Guangzhou, a mega-city in southern China. A ground-based instrument was used as a scrubbing coil collector to sample ambient air, followed by on-site analysis by high-performance liquid chromatography (HPLC coupled with post-column derivatization and fluorescence detection. The H2O2 mixing ratio over the 13 days ranged from below the detection limit to a maximum of 4.6 ppbv, with a mean (and standard deviation of (1.26±1.24 ppbv during the daytime (08:00–20:00 LT. Methyl hydroperoxide (MHP, with a maximum of 0.8 ppbv and a mean (and standard deviation of (0.28±0.10 ppbv during the daytime, was the dominant organic hydroperoxide. Other organic peroxides, including bis-hydroxymethyl hydroperoxide (BHMP, peroxyacetic acid (PAA, hydroxymethyl hydroperoxide (HMHP, 1-hydroxy-ethyl hydroperoxide (1-HEHP and ethyl hydroperoxide (EHP, were detected occasionally. The concentration of H2O2 exhibited a pronounced diurnal variation on sunny days, with a peak mixing ratio in the afternoon (12:00–18:00 LT, but lacked an explicit diurnal cycle on cloudy days. Sometimes a second peak mixing ratio of H2O2 was observed during the evening, suggesting that H2O2 was produced by the ozonolysis of alkenes. The diurnal variation profile of MHP was, in general, consistent with that of H2O2. The estimation indicated that in the morning the H2O2 detected was formed mostly through local photochemical activity, with the rest probably attributable to vertical transport. It is notable that relatively high levels of H2O2 and MHP were found in polluted air. The unexpectedly high level of HO2 radicals

  17. Magnetic resonance spectroscopy study of proton metabolite level changes in sensorimotor cortex after upper limb replantation-revascularization.

    Science.gov (United States)

    Ertem, Kadir; Alkan, Alpay; Sarac, Kaya; Onal, Cagatay; Bostan, Haci; Yologlu, Saim; Bora, Arslan

    2005-01-01

    We aimed to investigate the changes in proton metabolite levels at the motor and somatosensory cortex by magnetic resonance spectroscopy (MRS) after upper extremity replantation or revascularization. Nine patients who referred to our clinic suffering from major total (two) and subtotal (seven) amputation of the upper extremity were enrolled in this study. Mean time value between the injury and operation was 5.1 h. Mean follow-up period or mean time between the injury and MRS analysis was 26.2 months (ranging from 7 to 41 months). Voxels (TR: 2000; TE: 136 ms) were placed onto locations in the bilateral precentral and postcentral cortex area of the cerebral hemispheres that represent the upper extremity. Contralateral sides of the brain hemisphere that represent the injured extremity were accounted as control groups. Metabolite ratios [NAA (N-acetyl aspartate)/Cr (creatine) and Cho (choline)/Cr] of the motor and somatosensory cortex were calculated. The NAA/Cr and Cho/Cr metabolite ratios between the two groups were found to be insignificant, and these results may indicate that there is no remarkable somatosensorial cortex disruption or demyelination in these patients. Fifty-six percent of patients were found as functional according to Chen's scale.

  18. A retrospective study of upper arm replantation%上臂离断再植回顾性研究

    Institute of Scientific and Technical Information of China (English)

    糜菁熠; 芮永军; 赵刚; 华雍; 邱扬; 姚群; 俞君; 王骏

    2015-01-01

    目的:通过对上臂离断再植患者回顾性研究,探讨再植的手术指征、技术要点和康复方法。方法对2004年至2012年在我院施行的22例上臂离断再植患者进行回顾性研究。年龄平均33.3岁,81.8%为旋转及绞轧撕脱性损伤,其它为压砸切割、车轮碾压和重物压砸伤。肢体毁损严重度评分( mangled extremity severity score,MESS )平均7.5分,13例为7分,7例为8分,1例为9分,1例为10分。再植手术中,肢体缺血时间为5~10 h ,平均8.1 h,其中热缺血时间为4~7 h,平均6.2 h。术后分早、中、晚期开展不同的康复治疗。结果2例在术后第5、第10天因为肌肉坏死、严重感染及血管破裂而予以截肢,其余20例肢体成活。17例获得长期随访,随访时间3~10年,平均4.2年。17例 DASH 上肢功能评定平均为58.35±19.42;按陈中伟断肢再植功能评定标准,70.6%为良,29.4%为可,无优及差;64.7%患者对外观满意或较满意,47.1%患者对功能满意或较满意。结论除一般手术指征外,肢体通血时间必须控制在9 h 以内,正中神经和桡神经必须有效修复。创面应尽量选择皮瓣、肌瓣早期覆盖,在保护血管神经束的同时可以为晚期功能恢复创造条件。坚持长期不懈的康复治疗,是促进患者功能、心理和社交恢复的重要保障。%Objective To discuss the indication, surgical technique and rehabilitation of upper arm replantation by a retrospective study. Methods Twenty-two cases ( 2004-2012 ) of upper arm replantation were studied. The average age was 33.3 years old. In all patients, 81.8% were of rotation-twist-avulsion injury, and others were of crush-cut, wheel rolling or heavy crush injuries. The average MESS score was 7.5 points: 13 cases were 7, 7 cases were 8, 1 case was 9 and 1 case was 10. Ischemia time was 5-10 hours ( average: 8.1 hours ). Warm ischemia time was 4-7 hours ( average: 6.2 hours

  19. AN EQUILIBRIUM ANALYSIS OF ANTIBIOTICS USE AND REPLANTING DECISIONS IN APPLE PRODUCTION

    OpenAIRE

    Roosen, Jutta; Hennessy, David A.

    2001-01-01

    Antibiotics are used in fruit production to control fire blight, a bacterial disease of fruit trees that causes yield losses and eventually tree death. Fearing the development of widespread antibiotic resistance, scientists and public health officials are becoming increasingly concerned about antibiotics use in agriculture. A framework is developed for assessing the impacts of changes in tree damage risk following a ban on antibiotics use in the apple industry. Allowing for entry and exit, a ...

  20. Pulp and Periodontal Regeneration of an Avulsed Permanent Mature Incisor Using Platelet-rich Plasma after Delayed Replantation: A 12-month Clinical Case Study.

    Science.gov (United States)

    Priya M, Harini; Tambakad, Pavan B; Naidu, Jaya

    2016-01-01

    Numerous publications have reported revascularization of necrotic immature permanent teeth, but the regenerative potential of pulp in mature teeth has rarely been considered. Platelet-rich plasma (PRP) meets many requirements of a scaffold for regenerative endodontics. To the best of our knowledge, no clinical study has evaluated PRP for endodontic regeneration in a mature avulsed tooth. The present case evaluated PRP for pulpal regeneration in an avulsed mature incisor (>8 hours extraoral dry time) of an 11-year-old boy after delayed replantation. The canal was disinfected after extraoral access cavity preparation and pulp extirpation. The root apex was enlarged, and the tooth was placed in doxycycline solution for 20 minutes. After tooth replantation and splinting, PRP was injected up to the level of the cementoenamel junction and sealed with glass ionomer cement. The 6-month follow-up revealed evidence of internal and external root resorption with periapical radiolucency and an apparent periodontal ligament space. Access was reopened; slurry of 2 antibiotics (minocycline and metronidazole) was inserted into the canal and sealed. Nine- and 12-month radiographs revealed resolution of periapical radiolucency with no further progression of internal resorption. The tooth showed a positive response to thermal and electric pulp tests. The findings observed in this case warrant further research under controlled conditions to evaluate endodontic and periodontal regeneration in a tooth that would otherwise be expected to have an unfavorable prognosis. Copyright © 2016 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  1. Effect of replanting systems on populations of Strategus aloeus (L. and Rhynchophorus palmarum (L. associated with the oil palm OxG interspecific hybrid (Elaeis oleifera × Elaeis guineensis in Southwestern Colombia

    Directory of Open Access Journals (Sweden)

    Rodrigo Andrés Ávila

    2014-08-01

    Full Text Available The oil palm replanting process produces a large amount of organic matter that, as it begins to decompose, becomes a breeding ground for various pests, including Strategus aloeus and Rhynchophorus palmarum. Different crop replanting systems are being used today. The method used depends on the plantation and it is basically associated with the costs involved in the process. However, sometimes too little attention is paid to other issues related to the new crop, such as plant health and agronomic management. This study evaluated the effect of different crop replanting alternatives in relation to two pest populations affecting oil palm plantations. Pest populations of S. aloeus and R. palmarum were assessed and monitored for 27 months using seven replanting methods. It was found that the largest number of individuals of R. palmarum and S. aloeus was associated with the stem felling and stacking method. No individuals of the two pest species were found when the felling and burying method was used. The exposed organic matter method that had the lowest number of individuals of both pest species was the felling, chipping, spreading method.

  2. 断指再植术护理配合与体会%The Surgical Nursing Cooperation and Experience of Severed Finger Replantation

    Institute of Scientific and Technical Information of China (English)

    范晓勇; 郭明琴; 李香玲

    2014-01-01

    目的:探讨断指再植手术的最佳手术配合方式。方法:对57例断指再植患者(108指)的心理护理、物品器械准备、手术中洗手、巡回护士的配合及术中出现特殊情况的护理配合等进行回顾。结果:经过3个月的随访,其中2例患者(3指)因受伤时间过长、伤口污染严重,术后出现感染,血管破裂导致截指;2例患者(4指)再植成功后因指动脉栓塞无法吻合而截指外,其他患者断指再植全部成活。结论:术前的准备工作、有效的心理护理、术中的精心护理,可以降低发生血管危象的几率;严格执行无菌操作、熟练地护理配合能有效缩短手术的时间,减少伤口感染,提高再植成活率。%Objective:To discuss the optimal surgical nursing cooperation of severed finger replantation. Method:The situations such as the psychological nursing of 57 patients(108 fingers)with severed finger replantation,the preparation of articles and instruments,the cooperation of scrub nurses and circulating nurses during the operation,the surgical nursing cooperation with special situations appeared during the operation were reviewed. Result:By 3 months of follow-up,because of too long injury time and serious wound contamination,infection and angiorrhexis occur in 2 patients(3 fingers)among them after the operation,which lead to cut the severed fingers. 2 patients(4 fingers)had been cut the severed fingers after the successful replantation because the fingers can not match on account of artery embolization. Beyond that,the other patients’severed fingers were all survived after the replantation. Conclusion:The preoperative preparation work,effective psychological nursing and intraoperative meticulous nursing can reduce the probability of vascular crisis. Strictly executing aseptic manipulation and skillfully nursing cooperation can effectively shorten the operation time,reduce the wound infection and improve the

  3. Alcohol-inactivated autograft replantation in reconstruction of bone defects in management of malignant bone tumors%酒精灭活瘤段骨在重建恶性骨肿瘤骨缺损中的应用

    Institute of Scientific and Technical Information of China (English)

    许宋锋; 刘江; 聂鑫; 于秀淳; 徐明; 王冰; 郑凯; 付志厚; 宋若先

    2015-01-01

    .The overall 5-year survival rate was 42.5%,which was 54.5%in osteosarcoma group.Devitalized bone existed for a long time in 30 patients,among whom the overall 3-year survival rate was 57%( 30/53 ) and limb-salvage rate was 68%(36/53 ).The postoperative complications included incision infection (7.6%,4/53 ),fracture and internal ifxation breakage (9.4%,5/53),internal ifxation breakage (3.8%,2/53) and delayed union and non-union of inactivated bone (15.1%,8/53).The mean MSTS score was 27 (range: 19-33),and the mean ISOLS score was 26 (range: 22-31 ).The following results were achieved with the single factor analysis.(1) The length of alcohol-inactivated autograft was correlated with the occurrence rate of callus,the occurrence time of callus,postoperative recurrence rate,overall survival rate,MSTS score and ISOLS score (P<0.05).(2) There was a correlation between neoplasm staging and postoperative recurrence rate (P<0.05).(3) There was a correlation between joint preserving and MSTS score (P<0.05).(4) The disease course,neoplasm staging (P=0.026 ) and tumor location were correlated with the 3-year survival rate (P<0.05 ).The multiple-factor analysis showed the length of alcohol-inactivated autograft,duration of disease course and neoplasm staging were independent factors affecting the overall survival rate (P<0.05 ).Conclusions Alcohol-inactivated autograft replantation could be an option in reconstruction of bone defects in management of malignant bone tumors.Early diagnosis and treatment could increase the survival rate.The functional results will be improved with the decrease of alcohol-inactivated autograft length and preservation of articular surface.The length of alcohol-inactivated autograft,duration of disease course and neoplasm staging are independent factors affecting the overall survival rate.%目的 评价酒精灭活在重建恶性骨肿瘤骨缺损中的疗效,并分析影响疗效的相关因素.方法 回顾性分析1995年1月至2013

  4. 阴茎根部离断伤再植成功2例报告并文献复习%Study on 2 case reports of successful replantation of penis root

    Institute of Scientific and Technical Information of China (English)

    陈永绛; 罗立旷; 廖伟强

    2012-01-01

    Objective To report experiences on 2 successful cases of penile replantation, and explore method and key points for attention in penile amputation after replantation.Methods The application of microsurgical instruments was used in penile amputation for replantation.Results 2 cases after replantation of the penis survived completely,postoperative follow-up for 4 ~ 6 years,two patients with penile pain tactile recovered well,as well as the replantation of penis erectile function recovery,being able to engage in normal sexual life,without any complications such as urethral stricture.Conclusion To be familiar with the relevant anatomy,try to shorten the penile ischemia time during preoperative and intraoperative operation,high quality of anastomosis of penile vascular and nerve,postoperative care and rational drug use,are all the keys for successful penis replantation.%目的 报告2例阴茎离断伤再植成功的经验和体会,探讨阴茎离断伤后再植的方法及注意要点.方法 应用显微外科手段对阴茎离断伤进行再植.结果 本组2例患者术后再植阴茎均完全成活,术后随访4~6年,2例患者阴茎痛触觉恢复较好,再植成活的阴茎勃起功能恢复,能进行正常性生活,无尿道狭窄等并发症.结论 熟悉相应的解剖,术前、术中尽量缩短阴茎缺血时间,高质量吻合阴茎重要血管、神经,术后加强护理、合理用药,是阴茎再植成功的关键.

  5. Study on the Training Mode of Innovative Talents in Industry Transfer of PRD%珠三角产业转移中的创新型人才培养模式研究

    Institute of Scientific and Technical Information of China (English)

    魏国平; 邓彦; 李华军

    2011-01-01

    Essentially, industry transfer is the productivity in spatial layout, and the human capital plays a critical role of the adjustment for a successful industrial transfer. Based on the background of the Pearl River Delta industrial transfer, this paper discusses the industrial transfer in innovative talent training in local colleges and universities, from the perspective of the innovative talent, the industrial transfer and the inner mechanism of human capital, and then proposes some countermeasures for training innovative talents in the transfer of PRD industry.%产业转移,本质上是现有生产力在空间布局上的调整,其中人力资本对产业转移成功与否起到关键的作用.在珠三角产业转移的背景下,站在地方高校视角探讨产业转移需要的创新型人才培养模式,从分析创新性人才的必要性、产业转移与人力资本的内在机理出发,提出珠三角产业转移中创新型人才培养的相关对策.

  6. Cape Saint Paul Wilt Disease of coconut in Ghana: surveillance and management of disease spread

    Directory of Open Access Journals (Sweden)

    Nkansah-Poku Joe

    2009-03-01

    Full Text Available The Cape Saint Paul Wilt Disease (CSPWD, a lethal-yellowing type disease of coconut has been in Ghana since 1932. Aerial and/or ground surveys were undertaken to assess the current status of the disease spread. The survey showed that the spread of the disease for the past 5 years has mainly been the expansion of existing foci. However, new outbreaks were identified at Glidzi in the Volta, Bawjiase and Efutu Breman in Central regions. After the resurgence in the Volta region in 1995, the Woe-Tegbi-Dzelukope corridor has remained endemic, but less aggressive. Pockets of healthy groves remain along all the coastline and inland of known disease zones. Eradication of diseased palms at Ampain focus lying just about 60 km to the Ivorian border, and disease situations on new replanting with MYD × VTT hybrid are discussed.

  7. Replantation of digits

    Science.gov (United States)

    ... The bones are rejoined with wires or a plate and screws. Tendons are repaired, followed by nerves ... SW, Hotchkiss RN, Pederson WC, Kozin SH, Cohen MS, eds. Green's Operative Hand Surgery . 7th ed. Philadelphia, ...

  8. Improvement of Quantization Regression:an Empirical Research Based on PRD Manufacturing%量化回归的改进:基于珠三角制造业的实证研究

    Institute of Scientific and Technical Information of China (English)

    郭奕阳; 宋俏颖; 胡丽婷

    2015-01-01

    为了研究样本的大小与回归分析效果的关系并体现学科交叉的运用,以珠三角大中型制造企业为对象获取调查数据,利用改进的主成分分析求出各变量的综合评分,用于回归分析。根据回归分析坐标,画出其三维图。运用蒙特卡洛仿真证实大样本直接回归的不合理性,并通过聚类分析筛选有代表性的样本来改进回归分析。结论:使用筛选出的数据来进行回归分析,效果更好;应用:学术分析研究、大数据的信息挖掘和股价预测。%To study the relation between sample size and the effect on regression analysis ,and embody the application of interdisciplinarity ,with medium‐sized manufacturing enterprises of the PRD as an object of the research to obtain survey data ,modified PCA is utilized to gain the global score of variables ,which apply to regression analysis .With regression anal‐ysis coordinates ,its 3D is drawn .Subsequently ,Monte Carlo is applied to verify that the regression with a big sample is un‐reasonable to analyze directly ,and cluster analysis is used to select representative samples ,which is used for improving re‐gression analysis .Conclusion :it is better to utilize selected samples for regression analysis .Applications :analysis on aca‐demic researches ,information mining on big data and forecast on share price .

  9. 珠三角地区普通高校体育课程瑜伽教学现状与对策研究%PRD Current Situation of College Sports Course Yoga Teaching and Countermeasures

    Institute of Scientific and Technical Information of China (English)

    李群凤

    2015-01-01

    瑜伽是集健、力、美于一体的一项体育运动,颇受当代大学生的欢迎和青睐。本文以珠三角地区的普通高校公共体育课程瑜伽教学为研究对象,运用文献资料、问卷调查、专家访谈等研究方法,对珠三角地区普通高校公共体育课程中瑜伽教学现状进行深入研究,发现其中存在的问题,并在此基础之上提出建设性的意见,为促进珠三角地区普通高校公共体育课程的教学改革提供新的思路。%Yoga is one kind of sport with an integrtion of health ,power and beauty being popular with contemporary college students .This paper ,taking the Pearl River Delta College public sports curriculum teaching yoga for the example ,using literature ,questionnaire survey ,ex‐pert interviews and other research methods ,studied the Pearl River Delta College Public Sport Course in Yoga Teaching Situation ,eventurally found some problems and then proposed constructive comments on this basis to provide new ideas for promoting the teaching reform in PRD or‐dinary college PE courses .

  10. Investigation on leukocyte profile of periparturient cows with or without postpartum reproductive disease

    Institute of Scientific and Technical Information of China (English)

    Rafiqul Islam; HarendraKumar; BinsilaB. Krishnan

    2014-01-01

    Objective:To determine the leukocyte profile in periparturient cows and their relation with the development of postpartum reproductive diseases(PRD).Methods:Forty one advanced pregnant cows at240 days of gestation were selected and critically observed daily during the periparturient period.Blood sampling was done for each experimental animal on15 days prepartum(-15 d), calving day(0 d),15 days(15 d) and30 days(30 d) post partum(pp) for determination of total leukocyte(TLC) and differential leukocyte count(DLC) and thorough gynaecological examination was performed on0 d,15 d,30 d and45 d pp for diagnosis ofPRD like retained placenta(ROP), clinical metritis(CM), clinical endometritis(CE), cervicitis(CT) and delayed involution of uterus (DIU).Results:The percentage of cows suffered from various post partum reproductive diseases was41.46%(17/41).In normal cows, a significant increase inTLC from -15 d to0 d followed by significant decline has been observed at15 d and30 d.The cows suffering fromROP(25.52±2.49), CM(26.57±3.17) andCE(25.09±2.95) showed significantly(P<0.01) higher neutrophil% than normal cows(15.05±1.25) on day15 pp.The normal cows showed significant higher lymphocyte% during the periparturient period than the cows withPRD on post partum days(15 d and30 d).The neutrophil% and neutrophil: lymphocyte ratio increased from -15 d to the0 d in all the groups of cows followed by a general decrease during the post partum days.Conclusions:The neutrophil% and neutrophil: lymphocyte ratio was higher in the cows withPRD during periparturient period. Thus, theincreased neutrophil percentage and neutrophil: lymphocyte ratio observed at day15 postpartum is an indication ofPRD in cows.The significant rise inTLC on the day of calving than prepartum and post partum days only in normal cows is physiological.It is also clear that cows suffering fromROP most likely to suffer from other post partum reproductive diseases.

  11. A retrospective study of 50 replanted permanent teeth in children%儿童50 颗恒牙再植后的回顾性研究

    Institute of Scientific and Technical Information of China (English)

    管悦; 秦满

    2009-01-01

    Objective:To analyze the prognosis of replanted permanent teeth in children and associated factors. To determine the onset time of root resorption and related factors. Methods: Clinical data of replanted teeth treated in Department of Pediatric Dentistry, Peking University, School and Hospital of Stomatology, from January 2000 to December 2006,were collected, and the follow-up period was no less than six months. The Fisher's exact test and cox regression were used for statistical analysis. Results: The study comprised of 39 patients with 50 replanted permanent teeth. The periodontium healing rate was 18%, while root resorption rate was 82%. Replacement resorption was the most common type of root resorption (64%).The factors significantly affecting periodontium healing were stage of root development and storage of avulsed teeth.Stage of root development and the time of endodontic treatment significantly affected the onset time of root resorption(P<0.05). Conclusion: Replacement resorption is the most common type of root resorption. The factors significantly affecting periodontium healing are stage of root development and storage of avulsed teeth. Stage of root development and the time of endodontic treatment significantly affect the onset time of root resorption.%目的:分析再植牙的预后及影响预后的相关因素,观察再植后牙根吸收出现时间及影响因素.方法:对2000~2006 年于北京大学口腔医学院儿童口腔科注册的系统病历中,观察期≥6 个月的全脱位牙再植病历进行回顾性研究,记录患者及再植牙信息.应用卡方检验和生存分析(cox regression)进行统计学分析.结果:符合纳入标准的外伤病历39 份,涉及再植牙50 颗.牙周膜愈合的发生率为18%,牙根吸收发生率为82%,替代性吸收是最常见的牙周组织预后形式(64%).牙根发育情况和保存方式与牙周组织预后具有显著相关性;牙根发育情况、牙髓治疗时机可以影响牙

  12. Principios de evaluación y resultados funcionales en los reimplantes de miembro superior Principles of evaluation and functional results in upper extremity replantation surgery

    Directory of Open Access Journals (Sweden)

    D. Camporro Fernández

    2012-09-01

    Full Text Available El objetivo de este trabajo es evaluar nuestros resultados funcionales y subjetivos en pacientes sometidos a reimplante de miembro superior. Medimos rango de movilidad articular, fuerza de la prensión y otros tests en 41 pacientes con edad media 44,8 años que sufrieron amputación de miembro superior y fueron sometidos a reimplante quirúrgico en nuestro hospital entre enero del 2005 y diciembre del 2009. Los resultados funcionales se midieron con la tabla de Mayo modificada para lesiones de pulgar, dedos largos y mano, distal a muñeca. Las amputaciones proximales a muñeca se evaluaron según los criterios de Chen. Los resultados subjetivos fueron documentados aplicando a todos los casos el cuestionario de Russell. La mayoría de las lesiones fueron provocadas por mecanismos de avulsión y 30 (74 % fueron accidentes laborales. La tasa final de supervivencia fue del 85 % (35 pacientes incluyendo 2 pacientes en los que se realizó trasplante de pie a mano para salvar la amputación. Aplicando la tabla de Mayo modificada, los resultados fueron buenos en pulgar y discretos en mano y dedos largos. En reimplantes proximales obtuvimos 1 resultado excelente y 2 discretos. Diecinueve pacientes retornaron al mundo laboral en una media de 10 meses. Veintisiete manifiestan satisfacción alta con los resultados obtenidos. Los resultados de cualquier reimplante deben superar los del cierre simple de una amputación. Aunque los resultados objetivos de la serie son moderados, muchos pacientes retornan al trabajo y la mayoría es capaz de realizar sus actividades cotidianas.The aim of this study was to evaluate functional and subjective outcome after upper limb replantation, with assessment or range of motions, grip strength, and additional functional tests. Forty-one patients, mean age 44.8 years old, with upper limb amputations were treated in our hospital with replantation between January 2005 and December 2009. Functional results were assessed by

  13. Pelvic radiation disease: Updates on treatment options

    Science.gov (United States)

    Frazzoni, Leonardo; La Marca, Marina; Guido, Alessandra; Morganti, Alessio Giuseppe; Bazzoli, Franco; Fuccio, Lorenzo

    2015-01-01

    Pelvic cancers are among the most frequently diagnosed neoplasms and radiotherapy represents one of the main treatment options. The irradiation field usually encompasses healthy intestinal tissue, especially of distal large bowel, thus inducing gastrointestinal (GI) radiation-induced toxicity. Indeed, up to half of radiation-treated patients say that their quality of life is affected by GI symptoms (e.g., rectal bleeding, diarrhoea). The constellation of GI symptoms - from transient to long-term, from mild to very severe - experienced by patients who underwent radiation treatment for a pelvic tumor have been comprised in the definition of pelvic radiation disease (PRD). A correct and evidence-based therapeutic approach of patients experiencing GI radiation-induced toxicity is mandatory. Therapeutic non-surgical strategies for PRD can be summarized in two broad categories, i.e., medical and endoscopic. Of note, most of the studies have investigated the management of radiation-induced rectal bleeding. Patients with clinically significant bleeding (i.e., causing chronic anemia) should firstly be considered for medical management (i.e., sucralfate enemas, metronidazole and hyperbaric oxygen); in case of failure, endoscopic treatment should be implemented. This latter should be considered the first choice in case of acute, transfusion requiring, bleeding. More well-performed, high quality studies should be performed, especially the role of medical treatments should be better investigated as well as the comparative studies between endoscopic and hyperbaric oxygen treatments. PMID:26677440

  14. Effects of long-term continuous cropping on soil nematode community and soil condition associated with replant problem in strawberry habitat

    Science.gov (United States)

    Li, Xingyue; Lewis, Edwin E.; Liu, Qizhi; Li, Heqin; Bai, Chunqi; Wang, Yuzhu

    2016-08-01

    Continuous cropping changes soil physiochemical parameters, enzymes and microorganism communities, causing “replant problem” in strawberry cultivation. We hypothesized that soil nematode community would reflect the changes in soil conditions caused by long-term continuous cropping, in ways that are consistent and predictable. To test this hypothesis, we studied the soil nematode communities and several soil parameters, including the concentration of soil phenolic acids, organic matter and nitrogen levels, in strawberry greenhouse under continuous-cropping for five different durations. Soil pH significantly decreased, and four phenolic acids, i.e., p-hydroxybenzoic acid, ferulic acid, cinnamic acid and p-coumaric acid, accumulated with time under continuous cropping. The four phenolic acids were highly toxic to Acrobeloides spp., the eudominant genus in non-continuous cropping, causing it to reduce to a resident genus after seven-years of continuous cropping. Decreased nematode diversity indicated loss of ecosystem stability and sustainability because of continuous-cropping practice. Moreover, the dominant decomposition pathway was altered from bacterial to fungal under continuous cropping. Our results suggest that along with the continuous-cropping time in strawberry habitat, the soil food web is disturbed, and the available plant nutrition as well as the general health of the soil deteriorates; these changes can be indicated by soil nematode community.

  15. El Partido de la Revolución Democrática (PRD) en el Estado de México. Un balance de los resultados electorales y su posicionamiento como fuerza política importante en el sistema de partidos en la entidad (1996-2006)

    OpenAIRE

    Eduardo Rodríguez Manzanares

    2009-01-01

    El Estado de México ha observado en los últimos 10 años (1996-2006) una nueva composición en el sistema de partidos de un esquema hegemónico o dominante por parte del Partido Revolucionario Institucional (pri) a un pluralismo o multipartidismo, con énfasis en un tripartidismo, entre el pri, el Partido Acción Nacional (pan) y el Partido de la Revolución Democrática (prd), en el que este último ha avanzado de manera importante entre las preferencias del electorado, lo cual observamos como ejemp...

  16. Depressed polymorphonuclear cell functions in periparturient cows that develop postpartum reproductive diseases.

    Science.gov (United States)

    Islam, Rafiqul; Kumar, Harendra; Singh, Gyanendra; Krishnan, Binsila B; Dey, Sahadeb

    2017-09-01

    The study was planned to see if there is any important and significant changes in the PMN function in cows suffering from postpartum reproductive diseases (PRD). Blood sampling was done from 41 pregnant cows on 15 days prepartum (-15d), calving day (0d), 15 days (15d) and 30 days (30d) postpartum and thorough gynaecological examination was performed on 0d, 15d, 30d and 45d for diagnosis of PRD like retained placenta (RP), clinical metritis (CM), clinical endometritis (CE) and delayed involution of uterus (DIU). The heparinised blood was used for isolation of PMN leukocytes for estimation of superoxide (SO), hydrogen peroxide (H2O2) and enzyme myeloperoxidase (MPO) activity in each group of cows. The SO production (ΔOD) was greater for normal (0.19 ± 0.05) than cows suffering from RP (-0.12 ± 0.09), CM (-0.15 ± 0.13) and CE (-0.07 ± 0.05) at -15d. The mean value was greater for normal cows (0.12) than the cows with PRD (0.05 to 0.9) at 30d. The H2O2 production was greater for normal than cows with PRD at all sampling days and significantly greater than cows with RP and CE at 15d (p < 0.01) and 30d (P < 0.05). The MPO activity (μmol/1 × 10(7)) was greater for normal (18.77 ± 1.27) than for RP (12.52 ± 2.57) and CM (11.31 ± 3.30) cows on 0d. The depressed capability of the PMN from the cows with PRD to produce SO, H2O2 and MPO during the periparturient period indicated their association with the development of RP, CM and CE.

  17. Replantation of thumb or fingers with skin degloving injury in 30 patients: an outcomes evaluation%30例手指皮肤套脱伤再植术后疗效及评价

    Institute of Scientific and Technical Information of China (English)

    纪秉青; 侯瑞兴; 巨积辉; 金光哲; 王凯

    2016-01-01

    目的 报告应用再植术治疗手指皮肤套脱伤术后的疗效.方法 对我院自2007年至2012年30例共42指采用再植术治疗手指皮肤套脱伤的病例进行2~7年(平均4年)的随访观察,并将示指、中指、环指、小指套脱伤按撕脱平面分为Ⅰ度套脱伤和Ⅱ度套脱伤,应用中华医学会手外科学会断指再植功能评定试用标准及MHQ手功能评价标准对手指功能进行评定.结果 根据中华医学会手外科学会断指再植功能评定试用标准评定,30例手指皮肤套脱伤患者术后恢复优良率达93.3%,其中Ⅰ度皮肤套脱伤术后恢复优良率达100%,Ⅱ度皮肤套脱伤术后恢复优良率87.5%.根据MHQ手功能评价标准,患者主观评价得分较高.结论 运用再植术治疗手指皮肤套脱伤,修复的手指可最大限度地恢复外形和功能,其中Ⅰ度套脱伤术后恢复效果高于Ⅱ度套脱伤术.患者对术后恢复的满意程度较高.%Objective To report the clinical outcomes of replantation of thumb and fingers with skin degloving injuries.Methods Thirty patients with 42 avulsed thumb and fingers treated with replantation from 2007 to 2012 were follow-up for 2 to 7 years (average,4 years).Based on the level of the degloving injury,avulsion of the index,middle,ring and little fingers was categorized into grade Ⅰ avulsion and grade Ⅱavulsion.The results of replantation were assessed by the provisional functional assessment criteria for thumb and finger replantation issued by the Hand Surgery Society of Chinese Medical Association and by the Michigan hand outcomes questionnaire (MHQ).Results According to the provisional functional assessment criteria for thumb and finger replantation issued by the Hand Surgery Society of Chinese Medical Association,93.3 % of the cases achieved excellent and good results.This satisfactory rate was 100% in grade Ⅰ avulsions and 87.5% in grade Ⅱ avulsions.MHQ revealed high patient satisfaction

  18. Halo-vest头环在全头皮撕脱伤再植术中的应用%Application of Halo-vest head ring in replantation of total scalp avulsion

    Institute of Scientific and Technical Information of China (English)

    林涧; 吴立志; 郭宇华; 张天浩; 顾仕林; 王成; 陈忠义; 陈海啸

    2015-01-01

    Objective To investigate the clinical effect of Halo-vest head ring in the treatment of replantation of total scalp avulsion.Methods We treated 11 cases of total scalp avulsion with the anastomosis of arteriovenous vessels and Halo-vest head ring from December 2006 to February 2015.Results One patient' s replanted scalp got necrosis because of serious contusion which was healed without hair growth after free skin graft and dressing.All the scalp flaps in the other 10 patients survived.After 3-96 months follow-up, the wound completely healed, the scalp and hair grew well with satisfactory appearance.Conclusions The use of Halo-vest head ring for replantation of total scalp avulsion can effectively improve the survival rate and survival area.%目的 探讨采用Halo-vest头环进行全头皮撕脱伤再植治疗的临床疗效.方法 2006年12月至2015年2月,我们采取吻合动静脉血管+ Halo-vest头环治疗11例全头皮撕脱伤.结果 本组1例患者因头皮撕挫严重,再植术后坏死,给予游离植皮和换药后创面愈合,无毛发生长.其余10例患者再植全部成活,经过3 ~96个月随访,创面完全愈合,头皮、毛发生长良好,获得满意的外观.结论 利用Halo-vest头环进行全头皮撕脱伤再植处理,能够有效提高成活率和成活面积.

  19. 37例小儿断指再植不利因素分析及护理对策%Unfavorable factors of digital replantation in children and the relevant nursing strategies

    Institute of Scientific and Technical Information of China (English)

    彭爱萍; 王小艳; 陈亚兰

    2013-01-01

    目的 探讨小儿断指再植护理特点、方法及临床护理效果.方法 分析总结2010年7月至2012年7月37例小儿断指再植护理,针对小儿依从性差35例、情绪不稳定32例、体温波动31例、血管危象11例、父母日常护理知识缺乏35例,采用镇静、制动、保暖、禁烟、早期家属健康指导等护理措施.结果 再植指体动脉栓塞坏死1例,静脉栓塞坏死1例,成活35例,总成活率94.6%.结论 小儿断指再植难配合治疗护理,影响再植指体治愈和功能恢复的因素多而复杂,护理较困难.采用镇静、制动、保暖、禁烟、家属健康教育等方法,可取得了满意的疗效.%Objective To investigate the characteristics,methods,and clinical effects of nursing for children undergoing digital replantation.Methods The data on nursing for 37 pediatric patients who had undergone digital replantation during the period of July July 2010 to July 2012 were analyzed.Of the 37 patients,35 had poor compliance,32 had emotional instability,31 had unstable body temperature,and 11 had vascular crisis.The parents of 35 children lacked of a knowledge about daily care.The nursing measures including sedation,immobilization,keeping warm,non-smoking,and early family health education were taken.Results Arterial embolization and necrosis in the replanted finger developed in one child and venous thrombosis and necrosis occurred in one patient.The inplanted fingers survived in 35 children,with an overall survival rate of 95.2%.Conclusions It is difficult for pediatric patients undergoing digital replantation to cooperate with treatment and nursing care.The factors affecting the healing and functional recovery are various and complicated and thus nursing is difficult.Application of sedation,immobilization,keeping warm,non-smoking,family health education can obtain a satisfactory efficacy.

  20. Reimplante intencional en diente geminado con lesión endoperio tipo IV: Reporte de caso Intentional replantation gemina injured in tooth type IV endoperio: Case report

    Directory of Open Access Journals (Sweden)

    R.S. Rodríguez Rodríguez

    2012-10-01

    , persistent fistula, large periapical lesions, periodontal pocket, root anatomy of the tooth organ palate (palatine canal alleged and that the anatomy tooth is favorable to perform the procedure. The extraction and intentional replantation is the treatment in cases where the endodontic treatment fails and the anomaly dental periapical surgery also fail because only temporarily remove the lesion but not the cause it is the communication between the oral cavity and apical area. However, it is known that this treatment option can have risks and benefits, including tooth loss or possible ankylosis and with a success rate of 42.9%. The present case report describes the extraction and intentional replantation geminate tooth with a persistent periapical lesion of periodontal origin, with symptoms and fistula, after endodontic treatment complex, its evolution and success.

  1. A baseline measure of tree and gastropod biodiversity in replanted and natural mangrove stands in malaysia: langkawi island and sungai merbok.

    Science.gov (United States)

    Hookham, Brenda; Shau-Hwai, Aileen Tan; Dayrat, Benoit; Hintz, William

    2014-08-01

    THE DIVERSITIES OF MANGROVE TREES AND OF THEIR ASSOCIATED GASTROPODS WERE ASSESSED FOR TWO MANGROVE REGIONS ON THE WEST COAST OF PENINSULAR MALAYSIA: Langkawi Island and Sungai Merbok. The mangrove area sampled on Langkawi Island was recently logged and replanted, whereas the area sampled in Sungai Merbok was part of a protected nature reserve. Mangrove and gastropod diversity were assessed in four 50 m(2) (10 × 5 m) sites per region. The species richness (S), Shannon Index (H') and Evenness Index (J') were calculated for each site, and the mean S, H' and J' values were calculated for each region. We report low tree and gastropod S, H' and J' values in all sites from both regions. For Langkawi Island, the mean S, H' and J' values for mangrove trees were S = 2.00±0, H' = 0.44±0.17 and J' = 0.44±0.17; the mean S, H' and J' values for gastropods were S = 4.00±1.63, H' = 0.96±0.41 and J' = 0.49±0.06. In Sungai Merbok, the mean S, H' and J' values for mangrove trees were S = 1.33±0.58, H' = 0.22±0.39 and J' = 0.22 ±0.39; the mean S, H' and J' values for gastropods were S = 4.75±2.22, H' = 1.23±0.63 and J' = 0.55±0.12. This study emphasises the need for baseline biodiversity measures to be established in mangrove ecosystems to track the impacts of anthropogenic disturbances and to inform management and restoration efforts.

  2. Number of Visitors and Economic Growth of Tourism in PRD: A Cointegration Test Based on Panel Data%珠三角旅游接待人数与旅游经济增长实证分析——基于面板数据的协整检验

    Institute of Scientific and Technical Information of China (English)

    卢鹏宇

    2012-01-01

    在了解珠三角旅游经济发展现状的基础上,运用2005—2010年珠三角9市旅游接待人数与旅游收入的面板数据进行协整分析,构建珠三角9市旅游接待人数与旅游经济增长关系的实证模型,通过实证分析发现珠三角9市旅游经济发展的差异,最后根据结论提出政策建议。%After an analysis of the current situation of PRD's tourism economy, the paper adopts a cointegration analysis based on panel data of number of visitors and tourism revenue from 2005 to 2010 in nine cities in PR, creating an empirical model of the relationship between number of visitors and economic growth of tourism. The differences of tourism economy growth in the nine cities in PRD are pointed out, and suggestions are offered.

  3. 阴茎完全离断再植二例报告并文献复习%Penile replantation : two case reports and review of the literature

    Institute of Scientific and Technical Information of China (English)

    李贵忠; 何峰; 黄广林; 满立波; 刘坤; 沈余明

    2012-01-01

    nonabsorbable sutures.The second case was a 25-year-old man,presented to the emergency room 15 hours after distal penile amputation,which had 2 wounds as a result of self-mutilation caused by psychiatric problems.The urethra mucosa and corpus spongiosum were anastomosed.The cavernous body of the penis was reattached by suturing the tunics albuginea of each corpus cavemosum to the corresponding proximal segment using 4-0 polyglactic acid sutures.Results In the first case,the tourniquet was released after replantation,and the distal penis appeared to revascularize,as noted by the gradual increase in redness and size.An arterial pulse was detected,and the superficial penile veins displayed normal turgor,and no bleeding was found.On postoperative day 3,the penile skin started to necrotize.On day 12,the necrotic skin was superficially debrided,and a fistula was observed in the corresponding urethral segment.Two weeks later,the fistula was sutured with 4-0 interrupted synthetic absorbable suture,and a transposition flap to embed the whole injured penis shaft was created from the proximal scrotal skin.The glans was exposed.Two months after the second operation,the embedded penis was released from the scrotum.After follow-up of two years,the patient had glans re-epithelialization with normal voiding,sensation,and erections.In the second case,the glans was still pink,but the penile skin started to necrotize on postoperative day 3.On day 14,serious infections were noted,the necrotic skin was superficially debrided,and the amputated penis was relieved.Conclusions Prompt diagnosis and early treatment are essential to avoid the potential complications of ischemic necrosis and autoamputation.Venous outflow is a critical factor for success of replantation.Microsurgical reanastomosing of the dorsal penile vein,penile arteries,and dorsal nerves can be identified as the "standard" method for penile replantation.The bipedicled scrotal flap can provide adequate skin cover for penis defects.

  4. DISEASES

    DEFF Research Database (Denmark)

    Pletscher-Frankild, Sune; Pallejà, Albert; Tsafou, Kalliopi;

    2015-01-01

    Text mining is a flexible technology that can be applied to numerous different tasks in biology and medicine. We present a system for extracting disease-gene associations from biomedical abstracts. The system consists of a highly efficient dictionary-based tagger for named entity recognition...... of human genes and diseases, which we combine with a scoring scheme that takes into account co-occurrences both within and between sentences. We show that this approach is able to extract half of all manually curated associations with a false positive rate of only 0.16%. Nonetheless, text mining should...... not stand alone, but be combined with other types of evidence. For this reason, we have developed the DISEASES resource, which integrates the results from text mining with manually curated disease-gene associations, cancer mutation data, and genome-wide association studies from existing databases...

  5. The replantation method of upper limb's biplane mutilation in conjunction with soft tissue defect%上肢双平面离断合并软组织缺损的断肢(手)再植

    Institute of Scientific and Technical Information of China (English)

    喜占荣; 彭鹏; 周朝清

    2014-01-01

    Objective To explore the replantation method of upper limb's biplane mutilation in conjunction with soft tissue defect.Methods From January 2003 to January 2013,29 patients with upper limb's biplane mutilation in conjunction with soft tissue defect were treated.There were 21 males and 8 females with the average age of 28.6 years.The youngest one was 1 year old and the oldest one was 70 years old.All the cases underwent different replantation order and transplantation by using vascular and nerve and flap according to the lesion they suffered,including the defected plane and soft tissue.Results All replantation limbs were survived besides 2 cases with infection and 3 cases of delaying healed due to the part of tissue necrosis.Among all 29 cases,9 cases got excellent recovery,14 cases were in good condition,4 cases were poor and 2 cases were bad.The totally excellent and good rate of upper limb function was 79.3% according to the limb reattachment function evaluation criteria of Hand Surgery of the Chinese Medical Association.Conclusion It can obtain higher survival rate due to our different replantations and method of tissue replantation to cure double plane mutilation in conjunction with soft tissue defect of upper limb.%目的 探讨上肢双平面离断合并软组织缺损的再植方法.方法 自2003年1月至2013年1月,共完成各种上肢双平面离断再植的患者29例,其中男21例,女8例,年龄1~70岁,平均28.6岁.根据离断平面及软组织缺损情况的不同,采用不同的再植顺序并联合血管神经、皮瓣移植等方法进行处理.结果 29例再植肢体全部成活,但有2例患者出现伤口感染及3例患者出现局部软组织坏死而发生延迟愈合.所有患者采用中华医学会手外科学会断肢再植功能评定标准进行评分,优9例,良14例,差4例,劣2例,优良率为79.3%.结论 上肢双平面离断合并组织缺损需要根据离断平面的不同采用不同的再植顺序及合理的组织

  6. 双干型静脉皮瓣在撕脱性断指再植中的应用%Application of arterialized venous flap with double vein trunks in replantation of degloved fingers

    Institute of Scientific and Technical Information of China (English)

    周晓; 芮永军; 许亚军; 寿奎水; 姚群

    2011-01-01

    目的 报告双干型静脉皮瓣在撕脱性断指再植中的应用和临床效果.方法 2007年3月至2009年6月,采用前臂双干型静脉皮瓣游离移植修复伴有皮肤软组织缺损的撕脱性断指6例,损伤至入院时间为30 min至8 h,切取皮瓣面积为1.8cm×1.8cm~2.2 cm×5.8cm,供区创面直接缝合.结果 术后6例伤口均Ⅰ期愈合,断指再植全部存活;5例静脉皮瓣无肿胀,顺利存活;1例皮瓣早期肿胀明显,紫红色,并见散在小水泡,经拆除部分缝线、换药等对症处理后顺利存活.术后随访时间为6个月至2年.皮瓣及再植手指血运好,皮瓣质地软,弹性好、耐磨.根据中华医学会手外科学会断指再植功能评定试用标准评定;优4例,良1例,可1例;优良率为82.5%.结论 采用前臂掌侧双干型静脉皮瓣游离移植修复伴有皮肤软组织缺损的撕脱性断指,能最大程度地恢复手指的功能和外形.%Objective To report the application and results of venous flap with double vein trunks in replantation of degloved fingers.Methods From March 2007 to June 2009, 6 cases of soft tissue defect in the degloved finger were replanted with venous flap with double vein trunks.The interval between injury and operation was 30 minutes to 8 hours.All fingers were replanted by arterialized free venous flap from the ipsilateral forearm with double vein trunks.The flap was 1.8 cm×1.8 cm to 2.2 cm× 5.8 cm in size.The donor site was directly closed.Results Primary wound healing was observed in all 6 cases postoperatively.All the replanted fingers survived completely.In 5 cases the venous flaps survived uneventfully.In 1 case there was partial superficial necrosis of the flap which healed with conservative management.Postoperative follow-up ranged from 6 to 24 months.The flaps and fingers had good circulation, good texture and color match.According to the criteria for functional assessment of amputated finger issued by the Chinese Hand Surgery Society, the

  7. Replantation of composite tissue masses severed from dorsal fingers by vein bridging%桥接静脉法再植手指背侧离断复合组织块

    Institute of Scientific and Technical Information of China (English)

    从飞; 宋保平; 欧学海; 蔡鹰; 付华; 冯东旭

    2013-01-01

    Objective To explore the clinical effect of replantation of composite tissue masses severed from dorsal fingers by vein bridging. Methods 13 cases with composite tissue masses severed from dorsal fingers were replanted by vein bridging (only venous anastomosis) from June 2006 to August 2011. The effectiveness was evaluated after operation by observing the survival and complications of the composite tissue masses. Postoperative follow up ranged from 6 to 24 months, evaluating the appearance and function of the hand. Results Complete survival of the replanted composite tissue masses of the hand was achieved in 9 cases. Partial necrosis was seen in 2 cases. 2 cases had complete loss of the tissue masses. By 6 months to 2 years follow-up, the replanted tissue masses had a better appearance and lower elasticity. According to the function evaluation of the total active motion (TAM) scales, the result was excellent in 8,good in 3 and fair in 2, and the excellent and good rate was 84.6%. Conclusion It is an effective method that replantation of composite tissue masses severed from dorsal fingers by vein bridging, which has a high survival rate and good effect.%目的:探讨通过桥接静脉建立血液循环的方法再植手指背离断复合组织块的疗效。方法2006年6月-2011年8月,对13例合并肌腱或骨质离断的手指背复合组织块离断伤患者,急诊应用桥接静脉建立血液循环的方法再植离断组织块,术后观察其成活情况及并发症。结果本组9例再植组织块完全成活,2例完全坏死,2例部分坏死。所有病例随访6~24个月,再植组织块外观可,弹性稍差。依据中华医学会手外科分会上肢功能评定标准,优8例,良3例,差2例,优良率84.6%。结论桥接静脉法再植手指背侧离断复合组织块成活率较高,临床效果良好,是一种有效的治疗方法。

  8. 自残性断指再植患者心理评估及护理干预%Psychological assessment of patients with replantation of self-mutilation amputated finger and nursing intervention

    Institute of Scientific and Technical Information of China (English)

    陈永霞; 刘莉; 赵霞; 李玲; 刘华

    2012-01-01

    目的:探讨自残性断指再植患者心理状态及心理护理干预的方法和效果.方法:将56例自残性断指再植患者随机分为对照组和观察组各28例,对照组给予常规护理,观察组在常规护理的基础上给予心理护理干预.应用症状自评量表(SCL-90)分别在术前及术后10 d进行评估分析.结果:术后10 d观察组SCL-90躯体化症状、人际关系敏感、抑郁、恐惧、焦虑、精神病性因子分值均低于对照组(P<0.05).结论:自残性断指再植患者术前心理症状复杂,实施心理护理干预能有效地缓解躯体化症状,促进患者身心康复,降低手术应激反应及再植指体血管危象的发生,提高患者自残性断指再植的成活率.%Objective: To analyze the psychological assessment of patients with replantation of self - mutilation amputated finger and investigate the method of psychological nursing intervention and its effect. Methods: 56 patients with replantation of self- mutilation amputated finger were randomly divided into an observation group and a control group ( 28 cases in each group ). The patients in the control group received routine nursing care and the patients in the observation group received extra psychological nursing intervention on the basis of the routine nursing care. The Symptom Checklist ( SCL - 90 ) was used to make a psychological assessment of the patients before operation and on 10 days after operation. Results: The somatic symptoms and the factor scores of interpersonal sensitivity, depression, fear, anxiety and psychosis of SCL - 90 on 10 days after operation were lower in the observation group than those of control group ( P <0. 05 ). Conclusion: The preoperative psychological symptoms of the patients with replantation of self - mutilation amputated finger are so complex. The implementation of psychological nursing intervention can effectively relieve somatic symptoms,promote physical and psychological rehabilitation of the

  9. Reimplantes nas amputações por mecanismo de avulsão: táticas e técnicas para o sucesso Limb replantation after avulsion injuries: techniques and tactics for success

    Directory of Open Access Journals (Sweden)

    Renata Gregorio Paulos

    2012-01-01

    Full Text Available OBJETIVOS: Avaliação retrospectiva criteriosa de casos de reimplantes após amputação por avulsão. Avaliação de técnicas e táticas utilizadas que determinaram evolução satisfatória e bom resultado funcional. METÓDOS: Foram avaliados, retrospectivamente, prontuários de 43 pacientes que tiveram membros amputados por mecanismo de avulsão e reimplantados nos últimos 21 anos. RESULTADOS: A maior parte dos casos envolvia homens adultos jovens. A localização de amputação mais frequente foi do polegar. As técnicas e táticas cirúrgicas utilizadas isoladas ou conjuntamente incluem: enxertos de nervo, enxertos vasculares (veia ou artéria, transposição de feixe vascular digital, encurtamento do membro e reimplante heterotópico. A técnica mais frequentemente utilizada foi o emprego de enxertos venosos. A taxa de sobrevida dos reimplantes foi alta (93%, assim como a satisfação dos pacientes. CONCLUSÃO: Os reimplantes por mecanismo de avulsão dependem do correto diagnóstico de viabilidade anatômica e utilização de técnicas e táticas cirúrgicas apropriadas para cada caso. A experiência da equipe cirúrgica e estrutura hospitalar adequada são fundamentais para obtenção de bons resultados. Existem poucos relatos na literatura sobre indicação, tática, técnicas e resultados de procedimentos de reimplantes em amputações por avulsão. Acreditamos que a avaliação retrospectiva desta série de casos possa trazer novas informações e contribuições no atendimento desta situação de alta complexidade. Nível de evidência IV, Série de casos.OBJECTIVES: Retrospective evaluation of cases of limb replantation after avulsion injuries. Evaluation of the techniques and tactics used, that contributed to success and good functional results. METHODS: Forty-three patients' records were assessed. All the cases had been submitted to limb replantation after avulsion injuries. RESULTS: The majority of the cases were young men. The

  10. 十指与双前臂同时离断再植成功一例及文献复习%A case of successful replantation of simultaneous amputation of 10 fingers and both forearms and the literature review

    Institute of Scientific and Technical Information of China (English)

    张子清; 杨延军; 马立峰; 刘铭波; 王克列; 李木卫

    2016-01-01

    目的 探讨十指与双前臂同时离断再植手术方法和术后功能康复. 方法 2014年9月,应用显微外科技术,对一例十指、双前臂同时离断患者实施断肢、断指再植术.手术分3个再植团队,术中应用顺行再植与逆行再植方法交替,精确的血管、神经吻合,手术历时11h55min,术后2周康复团队介入,物理治疗与作业治疗相结合. 结果 术后再植肢体、手指全植全活.术后随访14个月,腕关节屈、伸活动功能正常,双手浅、深感觉功能恢复良好,拇、手指握、捏及对掌功能部分恢复,两点辨别觉8 ~ 10 mm;按中华医学会手外科学会上肢部分功能评定试用标准为良好. 结论 十指、双前臂同时离断,只要精心组织团队协作、应用娴熟的显微外科技术精细的吻合血管、神经,术后早期功能康复介入,再植肢、指可获得满意的功能恢复.%Objective To investigate the replantation and postoperative rehabilitation methods for simultaneous amputation of 10 fingers and both forearms.Methods A case of replantation for simultaneous amputation of both forearms and 10 fingers was carried out with microsurgery method in September,2014.The replantation involved 3 teams over 11 hours and 55 minutes to consequently conduct alternate anterograde and retrograde replantation and accurate blood vessels,nerve anastomosis and further followed with physical therapy and occupational therapy treatment in 2 weeks of the surgery.Results All the amputated arms and fingers revived after the surgery.After 14 months follow-up,function of wrist flexion and expansion was normal,superficial and deep sensory functions on hands were good,function of thumb and finger grip,pinch and opposition had partially recovered,the two-point discrimination was 8-10 mm,and all of above rated good according to the temporary criteria of the upper limb functionality set forth by Hand Surgery Branch of China Medical Association.Conclusion For the case

  11. 疼痛控制在吸烟患者断指再植术后血管危象护理中的应用%Pain Control in the Application of Nursing Care of Smoking Patients With Vascular Crisis After Replantation of Severed Fingers

    Institute of Scientific and Technical Information of China (English)

    郝敬红; 渠红; 施静

    2015-01-01

    Objective To study the value of pain control for vascular crisis of nursing in smoking patients after replantation of amputated finger. Methods 86 cases of replantation of severed finger smoking patients in our hospital were taken as the research object and diviede into the observation group and control group,The data were compared between groups. Results In the observation group,vascular crisis was significantly lower than that of the control group(P<0.05),observation group had significant advantages in comparison with data of replantation and nursing satisfaction rate(P<0.05). Conclusion Pain control for nursing in smoking patients after replantation of severed fingers can effectively reduce vascular crisis,so as to improve the survival rate of replantation,improve nursing satisfaction rate.%目的:对疼痛控制用于吸烟患者断指再植术后血管危象护理中的价值进行研究。方法选取我院86例行断指再植术的吸烟患者为研究对象,将其分为观察组和对照组,对相关数据进行组间比较。结果观察组血管危象发生率低于对照组(P<0.05);在再植成活率及护理满意率等数据的比较中观察组均具有优势(P<0.05)。结论疼痛控制用于吸烟患者断指再植术后护理中能够有效降低血管危象,改善再植成活率,提高护理满意率。

  12. 尿激酶和肝素钠在断指再植术后的应用%Comparison of curative effect of urokinase and heparin sodium after digital replantation

    Institute of Scientific and Technical Information of China (English)

    吴晓华; 樊涛; 严明忠

    2013-01-01

    Objective To contrast the curative effect of urokinase and heparin sodium after digital replantation.Methods All of 259 patients were randomly divided into urokinase group with 130 cases(217 fingers) and Heparin sodium group with 129 cases (199 fingers).Two groups received the same basic therapy,and respectively injected with urokinase and heparin sodium.The incidence rate of vascular crisis,survival percent of fingers and the recovery of finger function of two group were compared.Results The incidence rate of vascular crisis was 26.7 % and 36.7 % (P < 0.05),the survival percent of fingers was 88.9 % and 81.9 % (P < 0.05),the excellent and good rate of finger function was 69.3 % and 53.8% (P < 0.05),in 2 groups respectively.Conclusion Urokinase has more advantages than heparin sodium in treatment after digital replantation,with reducing the occurrence of vascular crisis,improving the survival rate of replantation of finger and promoting the finger function recovery.%目的 对比分析尿激酶和肝素钠应用在断指再植术后的治疗效果.方法 将259例断指伤患者随机分成尿激酶组130例(217指)和肝素钠组129例(199指),在基础治疗相同的情况下,分别使用尿激酶、肝素钠对再植术后断指进行治疗,比较2组的血管危象发生率、患指成活率、功能恢复等情况.结果 在尿激酶组、肝素钠组中,血管危象发生率分别为26.7%和36.7%(P<0.05),患指成活率分别为88.9%和81.9% (P <0.05),活动功能优良率分别为69.3%和53.8% (P <0.05).结论 在断指再植术后治疗中,尿激酶较肝素钠更能减少血管危象的发生率,提高患指的成活率,促进患指功能恢复.

  13. 凯时用于断指再植术后血管危象防治的临床研究%Clinical study of alprostadil injection for the prevention and treatment for vascular crisis after severed fingers replantation

    Institute of Scientific and Technical Information of China (English)

    戎晓敏; 李俊

    2014-01-01

    Object:to explore the effect of alprostadil injection used for the prevention of vascular crisis after replantation of severed fingers. Method:86 patients with 112 replanted fingers were randomly devided into 2 groups. The control group was given conventional treatment and the patients in treatment group were given alprostadil injection besides the conventional treatment. The incidence of vascular crisis, the coagulation function and blood rheology were analyze to evaluate the curative effect. Result:Compared with the control group, the treatment group was with low incidence of vascular crisis and reduce blood viscosity. The coagulation function was no significant difference between the 2 groups. Conclusion:It suggests thar in the finger replantation surgery, the alprostadil was of great clinical value for its prevention of thrombosis and reduction of the vascular crisis.%目的:凯时(前列腺素E1)在手足外科中用于断指再植术后预防血管危象的临床效果。方法我科86例112指断指再植病例,随机分为两组,对照组给予常规治疗,实验组在常规治疗的基础上使用凯时。对两组患者术后血管危象发生率、凝血功能及血液流变学进行统计分析,比较两组疗效。结果与对照组相比,实验组血管危象发生率低,血液粘度降低,两组凝血功能无明显差别。讨论凯时用于断指再植手术,能够预防血栓形成,降低血管危象的发生率,有较好的临床应用价值。

  14. Poverty-related diseases (PRDs): unravelling complexities in disease responses in Cameroon.

    Science.gov (United States)

    Makoge, Valerie; Maat, Harro; Vaandrager, Lenneke; Koelen, Maria

    2017-01-01

    In Cameroon, poverty-related diseases (PRDs) are a major public health concern. Research and policies addressing PRDs are based on a particular understanding of the interaction between poverty and disease, usually an association between poverty indicators and health indicators for a specific country or region. Such indicators are useful but fail to explain the nature of the linkages between poverty and disease or poverty and health. This paper presents results of a study among university students, unravelling how they perceive diseases, the linkages with poverty, their responses to diseases and the motivations behind reported responses. Based on the health belief model, this cross-sectional study was carried out among 272 students at the universities of Buea and Yaoundé in Cameroon. Data were collected using questionnaires containing items matching the research objectives. The questionnaires were self-completed. Malaria was considered as the most common disease perceived and also a major PRD. Contrary to official rankings of HIV/AIDS and TB, cholera and diarrhoea were considered as other major PRDs. Also, typhoid fever was perceived to be more common and a PRD than HIV/AIDS and TB combined. The most prominently attributed cause for disease was (lack of) hygiene. In response, students deployed formal and/or informal healthcare strategies, depending on factors like available money, perceived severity of the disease and disease type. Discrepancies were observed in respondents' response to diseases generally and to malaria in particular. Even though, overall, respondents pre-dominantly reported a formal healthcare response toward diseases in general, for malaria, informal responses dominated. There was an overall strong awareness and (pro)activity among students for dealing with diseases. Although the high use of informal facilities and medication for malaria may well be a reason why eradication is problematic, this seems to be a deliberate strategy linked to an

  15. 前臂再植术后患者早期预防手内在肌挛缩的康复护理%Rehabilitation nursing of patients after forearm replantation to prevent contracture of intrinsic muscle of hand

    Institute of Scientific and Technical Information of China (English)

    傅育红; 徐敏; 朱丽萍

    2013-01-01

    This paper introduces the rehabilitation methods and outcomes of patients after forearm replantation to prevent contracture of intrinsic muscle of hand.Nine patients with forearm replantation were treated by different orthosis for fixation and received physical therapy and occupational therapy to prevent contracture of intrinsic muscle of hand.Based on the test of finger joints functional recovery of hands(TAM) system,seven cases achieved to excellent grade of functional recovery;the two point discrimination of the finger pulp was 5~10cm;the touch sensation recovered to normal,the hand grip strength reached to 30kg,equal to 90% function of healthy side.One case achieved to good grade of functional recovery and one case was bad.Only one case was treated by functional reconstruction of hand intrinsic muscles.%报告了前臂离断再植术后预防手内在肌挛缩的康复训练过程和效果.对9例前臂离断再植术后患者在术后不同阶级采用不同的支具固定方法,进行相应的物理、作业疗法,预防前臂再植术后手内在肌挛缩.根据手关节活动范围系统评价标准,7例手功能恢复优,两点辨别觉5~10cm,触摸觉正常,握力30kg,相当于健侧手90%功能,中1例,差1例.本组仅1例行内在肌功能重建.

  16. Protein-Restricted Diets for Ameliorating Motor Fluctuations in Parkinson's Disease

    Directory of Open Access Journals (Sweden)

    Luxi Wang

    2017-06-01

    Full Text Available Levodopa is considered to be the most effective symptomatic drug for Parkinson's disease (PD. As the disease progresses, however, the patients are likely to experience a reduced response to levodopa and develop motor fluctuations (i.e., end-of-dose wearing off and unpredictable “on-off”. Protein-rich diets and elevated plasma concentrations of large neutral amino acids have been proved to impair the therapeutic effect of levodopa by reducing its absorption and influx into the brain. On the other hand, the protein-restricted diets including low-protein diet (LPD, protein-redistribution diet (PRD and PRD with use of low-protein products can all improve the efficacy of levodopa in patients with motor fluctuations. However, it should be noted that protein-restricted diets may also contribute to several side effects, including dyskinesia, weight loss, and malnutrition (e.g., protein and calcium insufficiency. Together, protein-restricted diets are an effective approach to improve motor fluctuations in PD patients, while long-term adherence to these diets requires monitoring for side effects.

  17. [Progress in improvement of continuous monoculture cropping problem in Panax ginseng by controlling soil-borne disease management].

    Science.gov (United States)

    Wang, Rui; Dong, Lin-Lin; Xu, Jiang; Chen, Jun-Wen; Li, Xi-Wen; Chen, Shi-Lin

    2016-11-01

    The continuous monoculture cropping problem severely has hindered the land resource of Panax ginseng cultivation and threatened the sustainable development of ginseng industry. There are comprehensive factors causing the continuous monoculture cropping problem, such as deterioration of soil physical and chemical properties, accumulation of allelochemical, increase of pesticide residue and heavy metal, imbalance of rhizospheric micro-ecosystem, and increase of soil-borne diseases. Among soil-borne disease was one of the key factors. More than 40 soil-borne diseases have been reported in the ginseng cultivation, especially, the diseases were more serious in the ginseng replanting land. Here main soil-borne diseases and their prevention way have been summarized, and we try to provide the effective improvement strategy of continuous monoculture cropping problem focusing on the disease control and offer reference for overcoming the ginseng continuous monoculture cropping problem. Copyright© by the Chinese Pharmaceutical Association.

  18. Nutrition in pelvic radiation disease and inflammatory bowel disease: similarities and differences.

    Science.gov (United States)

    DeWitt, Tiffany; Hegazi, Refaat

    2014-01-01

    Due to the intestinal inflammation, tissue damage, and painful abdominal symptoms restricting dietary intake associated with both diseases, patients with intestinal pelvic radiation disease (PRD) or inflammatory bowel disease (IBD) are at increased risk to develop protein calorie malnutrition and micronutrient deficiencies. In the current paper, we review the nutritional management of both diseases, listing the similar approaches of nutritional management and the nutritional implications of intestinal dysfunction of both diseases. Malnutrition is prevalent in patients with either disease and nutritional risk screening and assessment of nutritional status are required for designing the proper nutritional intervention plan. This plan may include dietary management, oral nutritional supplementation, and enteral and/or parenteral nutrition. In addition to managing malnutrition, nutrients exert immune modulating effects during periods of intestinal inflammation and can play a role in mitigating the risks associated with the disease activity. Consistently, exclusive enteral feeding is recommended for inducing remission in pediatric patients with active Crohn's disease, with less clear guidelines on use in patients with ulcerative colitis. The field of immune modulating nutrition is an evolving science that takes into consideration the specific mechanism of action of nutrients, nutrient-nutrient interaction, and preexisting nutritional status of the patients.

  19. 臂丛阻滞镇痛与自控镇静用于断指再植患者的护理%Nursing of replantation of amputated finger patients accepting brachial plexus block analgesia and patient-controlled sedation

    Institute of Scientific and Technical Information of China (English)

    岳红; 徐鹏; 郭俊光

    2010-01-01

    Objective To probe into nursing management methods of replantation of amputated finger patients accepting brachial plexus block analgesia and patient-controlled sedation (PCS) after operation.Methods 48 patients of replantation of amputated fingers accept continuous brachial plexus block analgesia and PCS after operation,Analgesia was 0.2% ropivaeaine,sedation was 0.05% midazolam or compositive liquid mixed 0.05% midazolam and 0.0005% fentanyl,the visual analogue scale (VAS),sedation scores and the changes of vital signs and side effocts after operation were recorded before the operation and at time intervals of 6,12,24,48,72 hours after the operation.Results The visual analogue scale(VAS)in the post-operation was obviously lower than the pre-operation,the Ramsay scores of PCS were higher than the pro-operation.There was no inadequate or excessive sedation.No influence was seen on respiration,circulation system and no other side effects happened.Conclusions Brachial plexus block analgesia and patient-controlled sedation (PCS) can offer a good Analgesia and sedation effect for patients of amputated fingers replantation,in period of analgesia and sedation,we should strengthen nursing and monitoring of vital signs to avoid accident.%目的 探讨臂从阻滞镇痛及自控镇静(PCS)用于断指再植患者术后镇痛镇静处理的效果及护理管理方法.方法 收集48例断指再植患者,术后行持续臂丛阻滞镇痛及静脉自控镇静,镇痛药物为0.2%罗哌卡囚,镇静药物采用0.05%咪唑地西泮或0.05%咪唑地西泮与0.0005%芬太尼复合液,观察术前及术后6,12,24,48,72 h时镇痛镇静评分、术后生命体征变化及不良反应.结果 术后镇痛评分明显低于术前;PCS后各时间点的镇静评分均高于术前,无一例镇静不足或镇静过度发生.患者术后呼吸循环稳定,无明显不良反应发生.结论 臂从阻滞镇痛及自控镇静能为断指再植患者提供良好的镇痛镇静效果,镇痛镇

  20. The impact of music on replantation rehabilitation of patients with negative emotions%音乐对断指再植术后康复训练患者负性情绪的影响

    Institute of Scientific and Technical Information of China (English)

    张扬云

    2015-01-01

    目的:探讨音乐对断指再植术后康复训练患者的负性情绪影响,并进行分析,以供参考。方法选取2011年10月~2014年10月我院收治的断指再植术后康复训练患者共72例,以此作为研究对象。并对其进行随机分为两组,每组各有36例患者。一组为实验组,该组患者采用音乐护理的方式进行临床护理;另一组为对照组,该组患者采用常规性护理法进行临床护理。两组在经过1个月的护理干预之后,运用抑郁自评表(SDS)和焦虑自评表(SAS)评估两组患者的抑郁、焦虑状况,并进行比较分析。结果对比两组患者的抑郁、焦虑状况,可以得出:实验组患者的抑郁、焦虑发生率均要明显低于对照组,且差异具有统计学意义(P <0.05)。结论音乐护理的方式在护理断指再植术后康复训练患者中有肯定的应用价值,其可以有效降低患者的抑郁、焦虑发生率,提高患者的生活质量,值得在临床医学护理中推广。%Objective To investigate the effects of music on negative emotions replantation rehabilitation patients, and analyzed for reference. Methods Selected October 2011 - 2014 October our hospital replantation rehabilitation patients with a total 72 cases, as the research object. And its randomly divided into two groups of 36 patients each. One group was the experimental group, the group treated with the music the way clinical nursing care; the other was the control group, the group of patients for clinical nursing care using conventional methods. Group 2 after a month in nursing intervention, the use of self-rating depression table (SDS) and anxiety self-assessment form (SAS) to assess depression, anxiety condition two groups of patients, and compared. Results Comparison of depression, anxiety condition two groups of patients, can be drawn: the experimental group were depression, anxiety incidence rate was significantly lower than the

  1. Relationship Between Dislocation Time and Prognosis in Vertical Fractured Posterior Teeth Replantation%纵折后牙黏结再植术中离体时间与愈合方式的关系

    Institute of Scientific and Technical Information of China (English)

    张珂; 盛乾斌; 王淑敏; 俞立英

    2012-01-01

    Objective;To investigate the relationship between dislocation time and prognosis in vertical fractured posterior teeth replantation. Methods; A total of 109 vertical fractured posterior teeth were extracted, treated with root canal therapy and spliced in vitro. The dentists treated root surfaces, adjusted occlusion; then replanted the teeth, sutured and fixed them. Followed up the patients and prognosis was evaluated by clinical examination, radiological examination and chief complaints of the patients. Results; The dislocation time of 109 vertical fractured posterior teeth varied from 25 minutes to 121 minutes. The total success rate was 81.6% (PLH 44.9%; OIH 36.7%). The success rate was 100% [pcriodontal ligament healing (PLH) 50% ; osscointcgration healing (OIH) 50%^] when the dislocation time was less than 30 minutes. The success rate was 89. 48% (PLH 42. 11% ; OIH 47. 37%) when the dislocation time was not less than 60 minutes. Conclusions; There was no correlation between dislocation time and prognosis in vertical fractured posterior teeth replantation.%目的:探讨纵折后牙黏结再植术中离体时间与愈合方式及效果的关系.方法:对109颗纵折后牙行牙拔除术,体外根管治疗后黏结,清除龈上龈下结石、刮除肉芽组织、根面处理、调合、再植、缝合.随访后分别从临床症状、X线片和患者主诉评价治疗效果,分析纵折牙在黏结再植术中不同的再植牙离体时间对愈合方式及效果的影响.结果:109颗牙纵折后黏结再植术中牙离体时间为25 ~121 min;再植成功率81.6%,其中牙周膜愈合率为44.9%,骨性愈合率为36.7%.离体时间<30 min者牙周膜愈合率和骨性愈合率均为50%,离体时间≥60 min者牙周膜愈合率与骨性愈合率分别为42.11%和47.37%.结论:纵折后牙黏结再植术中牙离体时间在25~121 min之间时,其与愈合方式及疗效无显著相关性.

  2. Rehablitation of the devitalization and replantation after resection of malignant tumor segment around the knee%膝关节周围骨恶性肿瘤瘤段切除灭活再植术的康复治疗

    Institute of Scientific and Technical Information of China (English)

    俞光荣; 蔡宣松; 梅炯; 郭获萍; 袁锋

    2000-01-01

    Objective To study the rehabilitation related to recovery of the limb function for the devitalizationand replantation after resection of malignant tumor segment around the knee. Methods Seventy nine patients with themalignant tumor around the knee (proximal tibia 21 cases, distal femur 58 cases) were reviewed. There were 35 malesand 44 females, aged ranged from 8 to 66 years (mean, 31.5 years). The tumors commonly seen were osteosarcomas(57), giant cell tumors (6), MFH (6) and chondrosarcomas (5). The devitalization and replantation after intraarticu-lar resection of tumor segment (CRIRT) was performed in 75 cases, that after extraarticular resection of tumor seg-ment (CRERT) was used in 4 cases. Functional training with different programs were performed in three periods aftersurgery. Results Seventy nine patients were followed up for 1~ 7 years (mean, 4.2 years). 5 years survival rate was42 % (33 cases). Functional assessment using Ennekings criteria was evaluated. The mean score in 44 cases of CRIRTwas 20(14~25) points and satisfactory (good or excellent results were 77% (34/44). The mean score in 4 CRERTcases was 24(22~28) points and all were satisfactory. Conclusion The devitalization and replantation after resectionof tumor segment is a good limb salvage surgery for malignant tumor segment around the knee. Rehabilitation programshelp recovery of the limb function. (Shanghai Med J, 2000,23:724-727)%目的 探讨膝关节周围骨恶性肿瘤瘤段切除灭活再植术功能恢复相关的康复治疗。方法本组79例,其中胫骨上端21例,股骨远端58例。常见肿瘤中骨肉瘤57例,巨细胞瘤6例,恶性纤维组织细胞瘤6例,软骨肉瘤5例。关节内瘤段切除灭活再植75例,关节外瘤段切除灭活再植4例。术后分3个阶段采用不同的康复计划进行功能训练。结果79例随访1~7年(平均4.2年),5年生存率42%(33例)。按Enneking法功能评定,关节内瘤段切除灭活再植44

  3. Clinical retrospective analysis of children for mixed dentition traumatic anterior teeth completely dislocation replantation%替牙期外伤性前牙完全脱位再植术的临床分析

    Institute of Scientific and Technical Information of China (English)

    赵然; 李凤和; 陈光

    2012-01-01

    目的:探讨替牙期完全脱位前牙再植术后的效果和相关影响因素.方法:对48例患儿58颗完全脱位前牙治疗方法和临床疗效进行分析.脱位前牙再植后复诊行牙髓测试、牙周检查,2周牙髓活力阴性的患牙行根尖诱导成形术,6个月~3年根尖孔完全形成后行根管永久充填治疗.结果:再植术后3年,5颗患牙活力存在,牙髓存活率达8.62%; 53颗患牙行根管治疗术后行X线检查,25颗患牙牙根牙周膜愈合,30颗患牙牙根部分牙周膜愈合和部分骨性愈合,3颗患牙不同程度牙根内外吸收,但无1例脱落.结论:早就诊且合理处理脱落牙、牙髓血管再生是牙再植术成功的关键,根尖诱导成形术可使替牙期牙根再度形成,牙骨质沉积于根端、封闭根尖孔,是替牙期脱位前牙治疗的重要手段,根管治疗可预防或减少脱位牙牙根的吸收.%Objective To explore the effects and related influential factors of replantation after complete dislocation of anterior teeth/tooth on mixed dentition patients experiencing tooth transitions. Methods Analysis of 48 patients with 58 traumatic anterior teeth were made based on treatments recieved and clinical observations.After the reimplantation for the traumatic anterior teeth, patients returned for dental pulp test and periodontal examination. 2 weeks later, apexification was performed after the dental pulp test had indicated a negative result.Six months to 3 years after apexification, permanent canal filling treatment was made once the apical had been fully formed. Results three years after the replantation,5 teeth exist vitality with a dental pulp survival rate of 8.62%; X-ray examination indicates that out of the 53 teeth have had apexification and canal filling treatment:25 teeth's tooth roots have periodontal ligament fully recovered (bined together or have been healed),30 teeth's teeth root have fully recovered iodontal ligaments and partial recover of the bone

  4. Rhizosphere microbial community variation of apple orchard soil with different tree age and the effect on replanted apple rootstock%不同树龄苹果园土壤微生物的差异及对苹果砧木生长的影响

    Institute of Scientific and Technical Information of China (English)

    王树桐; 梁魁景; 王亚南; 邹庆甲; 曹克强

    2011-01-01

    以平顶海棠(Malus robusta Rehd.)为试验材料,以4个不同树龄苹果园的土壤为对象,研究了不同树龄苹果园土壤对再植平顶海棠幼苗生长的影响.结果表明,在前茬树龄为3、8、15和24 a苹果园土种植的平顶海棠幼苗比正茬土对照的平均株高分别减少31.22%、46.38%、57.66%和63.10%;再植平顶海棠幼苗地上部干质量分别减少0.96%、57.58%、76.88%和78.10%;地下部干质量分别减少40.38%、48.79%、64.03%和79.43%.在24 a生苹果树土壤中再植海棠幼苗校正发病率达到了72.73%,而在3 a生苹果树的土壤中再植海棠幼苗校正发病率只有18.18%.对不同树龄的苹果园土壤根际细菌和真菌群落结构的差异进行分析,其结果为,随着苹果树龄的提高,根际土壤中真菌种类和数量显著增加,而细菌的种类和数量则随着树龄的增加显著减少.%Malus robusta Rehd. seedlings were planted in the soil collected from four apple orchards with different tree ages located in Qingyuan County to explore the influence of the soil with different tree ages on the plant growth and disease severity of replanted M. robusta seedlings. The results indicated that the seedlings planted in 3, 8, 15 and 24-year old orchard soils decreased by an average of 31.22%, 46.38%,57.66% and 63.10% in height; 0.96% ,57.58% ,76.88% and 78.10% in shoot dry weight, 40.38%、48.79% ,64.03% and 79.43% in root dry weight. The corrected disease incidence of the seedlings in the 24-year old soil reached 72.73% while only 18.18% in the 3 year-old soil. The total DNA was extracted from the soil and amplified by PCR with the 16S rDNA and 18S rDNA specific primer pairs, Subsequently, the rhizosphere bacteria and fungal community structure differences among the apple orchard soil with different tree age were analyzed by denaturing gradient gel eleetrophoresis (DGGE). The results showed that the composition of soil fungal species increased

  5. 自体富血小板纤维蛋白用于延迟牙再植1例%Using platelet-rich fibrin as an autologous media for delayed teeth replantation:a cases report

    Institute of Scientific and Technical Information of China (English)

    王伟; 黄超; 刘艳丽; 赵寅华; 张旻; 陈永进

    2016-01-01

    PRF ( platelet rich fibrin) is a kind of second generation platelet concentrate with a three dimensional reticular structure which can regulate inflammation, accelerate tissue healing, and release a variety of growth factors slowly and continuously. However, no clinical study has used PRF for the treatment of avulsed tooth. In this study, a delayed and dry-reserved avulsion tooth was replanted with autologous PRF. 12-month follow-up showed that the tooth recovered well, the peridental membrane was healed, no root resorption occurred, and the height of alveolar bone was restored.%富血小板纤维蛋白( PRF)是一种立体三维网状结构的第二代血小板浓缩物,它能够调节炎症,促进组织愈合。并且能够缓慢持续释放多种生长因子。大量文献报道PRF可以促进口腔软硬组织的愈合,但尚未将其应用于临床牙再植的治疗中。本文联合自体PRF颗粒对1例撕脱2 h且干燥保存的离体牙进行延迟再植、复位固定及后续牙髓治疗。随访1年,脱位牙恢复良好,达到牙周膜性愈合,没有出现牙根吸收,且牙槽骨高度得到恢复。

  6. A analysis of nursing cooperation during intentional replantation microsurgery%四手操作应用于意向性牙再植术的护理探讨

    Institute of Scientific and Technical Information of China (English)

    李雪; 贾春蓉; 赵晓曦

    2016-01-01

    目的:   探讨意向性牙再植术中护理配合的操作流程与规范。方法  选取难治性根尖周炎且需要行意向性牙再植的患牙14例,护士配合医生在显微镜下四手操作进行意向性牙再植术。结果  初步建立了意向性牙再植术的护理操作流程与规范,术后复查,除1例牙因松动拔出外,其余13例收到满意的临床效果。结论  高效规范的护理配合对确保意向性牙再植术的成功具有重要作用。%Objective   To discuss the nuring procedure and criteria of intentional replantation(IR) microsurgery. Methods  Fourteen cases of apical periodontitis were included according to including criteria. During the surgery, nurse helped the endodotic specialist  to finish IR with four-hand operation method. Results   The nuring procedure and criteria of IR was established. Thirteen teeth have no periapical symptoms with normal gingival attachment and tooth mobility. One tooth was extracted because of root resorption. Conclusion  The effective and qualified nursing cooperation play an important role to enhance the success rate of IR.

  7. Analysis of the Changes in Circulation of Sub-dermal Vascular Network Flap Made from Flap-type Skin Avulsion and Replanted to Origin Site%皮瓣型皮肤撕脱伤修成暴露真皮下血管网皮瓣回植创面的血循环变化分析

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Objective: To find out the characteristics of the changes in circulation of sub-dermal vascular network flap made from flap-type skin avulsion Injury and replanted to origin site. Method: Pig skin avulsion model was used in this experiment. Flap's blood circulation was monitored and surviving flap length measured. Result. Flap blood circulation was markedly improved. Conclusion: Sub-dermal vascular network flap made from skin avulsion flap and replanted to origin site can improved the survival length of the flap.%目的:了解皮肤撕脱伤修成暴露真皮下血管网皮瓣回植创面的血循环变化特点和对皮瓣成活的影响。方法:以猪为实验对象,制作皮肤撕脱伤模型,观察皮瓣的血循环变化和成活情况。结果:将撕脱瓣修成暴露真皮下血管网的皮瓣再回植,可以使皮瓣血循环显著改善。结论:将撕脱瓣修成暴露真皮下血管网的皮瓣再回植,可以使皮瓣成活长度显著增加。

  8. 网络特征对创新产业集群成长的影响研究--以珠三角地区信息服务产业为例%Influence of Network Characteristics on Innovative Industry Cluster Growth:Take PRD Information Services Industry Cluster as an Example

    Institute of Scientific and Technical Information of China (English)

    胡平; 邵鹏; 温春龙

    2013-01-01

    在产业集群和社会网络理论基础上,通过构建“企业-行业”隶属网络,研究集群网络特征对创新集群成长的影响。通过珠三角地区信息服务业集群数据的实证分析,研究结果表明:企业软件著作权的增加、整网规模的扩大、R&D投入占比的提高、政策推出对产值增长和就业增加有显著的正向影响;集群内企业数量的增长并不能有效提升网络内部信息的传播扩散效应;整网密度的提高会促进集群网络小世界的形成,却不能带来产值和就业的增长;群体中心性的提高会削弱小世界特征的形成,抑制产值和就业的增长;软件著作权、产值和个网规模的增加均对整网规模的扩大有显著的正向作用。%Based on the theory of industrial clusters and social network, we build up affiliation network of 'enter-prise-industry', proposed the model and hypothesis of 'innovation enterprises growth-network characteristics-innova-tion cluster growth'. By using empirical analysis on PRD information services industry cluster, we got conclusions that the growth in the number of corporate patents, the expansion of whole network scale, the increase of R&D investment and the policies have significant positive impacts on the output and employment. The increase in pat-ents, outputs and ego network scale have significant positive impacts on the expanding of whole network scale. The increase in whole network density will promote the formation of the small world, but cannot bring about the growth of output and employment. The improvement of group centrality will weaken the formation of small-world character, and inhibit the growth of output and employment. The growth number of firms cannot effectively im-prove the network internal information spread efficiency.

  9. Changes in expression of matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in pathological scar tissue of rabbit ears after scar-skin replantation%兔耳病理性瘢痕皮回植术后组织中基质金属蛋白酶-1及金属蛋白酶组织抑制剂-1表达的变化

    Institute of Scientific and Technical Information of China (English)

    赵雪莲; 苏晓光; 张锤; 张春莉; 张卓男; 郑宝恒

    2014-01-01

    目的 通过建立兔耳模型观察基质金属蛋白酶-1 (matrix metalloproteinase-1,MMP-1)及金属蛋白酶组织抑制剂-1(tissue inhibitor of metalloproteinase-1,TIMP-1)在病理性瘢痕皮回植术后组织中表达的变化,探讨瘢痕皮回植治疗病理性瘢痕的机制.方法 建立兔耳病理性瘢痕模型,共分为3组:正常皮肤组(对照组,A组)、病理性瘢痕组(B组)及瘢痕皮回植组(C组).切取标本行HE染色和Masson特殊组织化学染色及免疫组织化学染色,观察各组标本MMP-1、TIMP-1的表达情况.结果 病理性瘢痕经瘢痕皮回植术后,MMP-1及TIMP-1均较A组明显升高(P<0.01),MMP-1的表达较TIMP-1明显增强(P<0.01).结论 瘢痕皮回植术治疗瘢痕的机制与瘢痕组织内MMP-1和TIMP-1相互作用的失衡有关.%Objective To observe the changes of MMP-1 and TIMP-1 expression in the pathological scar tissue after scar-skin replantation and to explore the mechanism of treating pathological scars with scar-skin replantation through a rabbit ear model.Methods Rabbit ears were used to establish the hypertrophic scar animal model in this study.Specimens were taken for three times:normal skin,hypertrophic scar and scar-skin replantion separately.We then performed HE staining,Masson staining and immunohistochemical staining to observe the expression of MMP-1 and TIMP-1 in these three groups of specimens.Results The expression of both MMP-1 and TIMP-1 significantly increased in the hypertrophic scar tissue after scar-skin replantation compared with the control group (P<0.01).The expression of MMP-1 increased more significantly than that of TIMP-1 (P<0.01).Conclusions The mechanism of scar-skin replantation's effect in the treatment for hypertrophic scar is relevant to the imbalance in the interaction between MMP-1 and TIMP-1 in the scar tissue.

  10. Impacto do manejo de resíduos orgânicos durante a reforma de plantios de eucalipto sobre indicadores de qualidade do solo Impact of organic residue management on soil quality indicators during replanting of eucalypt stands

    Directory of Open Access Journals (Sweden)

    Guilherme Montandon Chaer

    2007-12-01

    priorizaram a conservação dos resíduos orgânicos por ocasião da reforma do povoamento. Contrariamente, as áreas onde ocorreu a remoção ou a queima do material orgânico da superfície do solo foram as que mais se distanciaram da área de referência. Esses resultados demonstram que o sistema de manejo adotado na reforma dos povoamentos de eucalipto analisados influencia, em médio prazo, o potencial dos solos de estocar e ciclar nutrientes por meio da biomassa microbiana e das atividades bioquímicas ligadas a ela. A maior aproximação entre a área com vegetação nativa e a de eucalipto com 11 anos leva a supor que ciclos mais longos nas florestas de eucalipto, contrastando com o padrão atualmente em uso no Brasil (cerca de sete anos, pode ser relevante para se manter a sustentabilidade da atividade florestal em longo prazo, a despeito de uma menor produtividade média anual. Nesse caso, a opção pela produtividade de curto ou médio prazo, ou pela sustentabilidade do uso do solo, com a conseqüente manutenção da sua qualidade para as gerações futuras, poderá ser repensada a partir dos dados aqui apresentados.Agricultural soil use induces changes in soil physical, chemical, and microbiological characteristics. These changes can eventually lead to a loss of soil quality and a consequent reduction in plant growth and productivity. The analysis of biochemical and microbiological soil quality indicators is relevant to monitor changes in soil quality and in the performance of key soil functions, such as the capacity of nutrient cycling and storage. This study reports on physical, chemical, and biochemical/microbiological quality indicators of soil under eucalyptus plantation, evaluated 5.5 years after the site had undergone different management practices during stand replanting. Evaluations were based on the determination of 18 physical or chemical besides 12 biochemical or microbiological attributes that are considered soil quality indicators. The

  11. Reconstruction of foot flexion-extension function after replantation of amputated leg%小腿中段离断再植后重建足跖屈背伸功能

    Institute of Scientific and Technical Information of China (English)

    陈秋生; 余斌; 杨建成; 江浩; 陈霞; 竺筠雯

    2001-01-01

    Objective To investigate the foot function reconstruction after replantation of amputated leg. Methods The n erveless injury muscle in the amputated limbs was cut off, a section tensor fascia lata was resected off to replace the injured muscle. Meanwhile, transfer biceps femoris muscle and sartoriu s muscle to strengthen extensive muscles, and transfer semimembranosus muscle an d gracilis muscle to strengthen flexion muscles. Postoperation functional exer cises of the ankle was carried out. Results 2 patients were tre ated with this t echnique, followed up for more than 2 years. The extension and flexion muscle st rength reached MRC4 with satisfactory ankle function, the range of motion of ank le was restored nearly to normal. Conclusion The technique is e ffective to reconstruct most functions of the normal muscles and restore foot function.%目的 探讨小腿中段离断再植后足跖屈背伸功能重建的方法 。方法 常规断肢再植,术中将离断肢远段失神经支配的肌组织切除,只 保留肌腱及肌腱膜,切取髂胫束条桥接远端背伸肌腱和近端肌腹,同时和前移缝匠肌、股二 头肌长头缝接,加强足背伸肌力;桥接远端跖屈肌腱和近端肌腹,同时和游离的半腱肌、股 薄肌缝接,加强足跖屈肌力。结果 治疗2例,分别随访2年8个月及2年5个 月,足背伸、跖屈肌力达Ⅳ~Ⅳ+,踝关节活动度近正常。结论 应用髂 胫束条桥接远断端的肌腱和近断端的正常肌组织,同时利用缝匠肌、股二头肌、半腱肌、股 薄肌加强足的背伸、跖屈肌力,是一种有效的功能重建方法。

  12. Replantation of severed limbs(fingers) at high altitude district:a clinical analysis of 248 cases%高原断肢(指)再植248例临床分析

    Institute of Scientific and Technical Information of China (English)

    韩国栋

    2001-01-01

    Objective To study the influence of coldness and hypoxia on thesevered limbs (fingers).Methods Retrospective analysis was done for 248 cases of severed limbs(fingers) at high altitude district in Qinghai province. The replantation sequence followed as normal procedure. But the number of arteries and veins anastomosed should be as many as possible. Sufficient blood volume and oxygen should be maintained with room temperature over 25 ℃.Results Overal viability rate was 90.8 % in 248 cases. 23 cases resulted in failure due to ischemic time over 10 hours.Conclusions Coldness at high altitude district provided tolerated ischemic warm time for detached limbs(fingers). People at high altitude district living in long - term hypoxia environment may increase adhensiveness of red blood cell and platelet, resulting in thrombosis after vessel anastomosis.%目的分析高寒、缺氧对断肢(指)再植的影响。方法对在青海省高原环境条件下行断肢(指)再植的248例病史作回顾性分析。再植顺序按断肢(指)再植常规,但应尽可能多地吻合动脉和静脉。在术中、术后保持一定的血容量、充足的氧气,室温需维持在25℃以上。结果248例的总成活率达90.8%。失败23例,大都为再植时限在10h以上者。结论高原地区的寒冷给离断肢(指)体提供了很好的冷藏条件,有利于提高成活率;高原地区人群的长期缺氧可增加血小板、红血球的粘附性,容易导致吻合后血管的血栓形成。

  13. Technological Advances in Huanglongbing (HLB or Citrus Greening Disease Management

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    Krishna Prasad Paudyal

    2015-12-01

    Full Text Available Huanglongbing (HLB, previously citrus greening disease, is the most destructive of citrus species causing major threat to the world citrus industry. The disease was reported from China in 1919 and now known to occur in more than 40 different countries of Asia, Africa, South and North America. Three species of gram negative bacterium namely Candidatus Liberibacter asiaticus, Candidatus Liberibacter africanus and Candidatus Liberibacter americanus are the casual organisms of HLB, respectively prevailing in the continent of Asia, Africa and South America. It is one of the most extensively researched subjects in citriculture world. HLB was detected in 2004 and 2005, respectively in San Paulo of Brazil and Florida of USA: the two leading citrus production hub of the world causing huge economic loss within 5 years of first detection. Since then research on HLB detection and management was further accelerated in American continents. This paper presents the scientific advancement made on detection, spread, economic losses caused by HLB in different parts of the world and controlling management strategies. Remarkable achievements have been made on HLB detection techniques including iodine test, qPCR and more recently in spectroscopy. While efforts are being made to develop resistance varieties using conventional and biotechnological tools management strategy which includes reduction of inoculums source, vector control and replant with disease-free planting materials still remains major option for HLB control. Citrus intercropping with guava have shown promising results for vector reduction.

  14. Experimental study on micro replantation repair of rabbit model of the foot skin degloving injury%显微回植修复兔模型前足皮肤脱套伤的研究

    Institute of Scientific and Technical Information of China (English)

    邱中杰; 尹宗生

    2015-01-01

    目的 探讨在显微镜下回植皮肤,修复兔模型前足皮肤脱套伤的应用效果.方法 选择新西兰大白兔48只,通过装置模拟利器切割撕脱、重物挤压前足等场景,造成大白兔前足脱套伤合并胫骨、跖骨、指(趾)骨骨折等,建立大白兔前足皮肤脱套伤的动物模型,成功41只,并采用内固定趾骨或胫骨骨折,在显微镜下修复断裂肌腱,吻合前足断裂的动脉及相应神经,并将背侧皮肤向远侧掀起,通过直接吻合、转位吻合、移植桥接等方法,逐平面的吻合背侧的动静脉,使皮肤复位,至创缘时吻合创缘皮下浅静脉,缝合皮缘,并放置橡皮引流条.术后石膏固定兔模型前足,抗炎抗感染.结果 41只兔模型回植的皮肤全部成活,3只兔模型创缘皮肤部分坏死,经换药创面愈合.术后X线复查,趾骨胫骨骨折对位好.对兔模型随访3~9个月,平均5个月,骨折和皮肤创面愈合良好,前足可正常行走.结论 在显微镜下回植皮肤,修复兔模型的前足皮肤脱套伤,有效恢复了伤足的供血,加速了骨折的愈合,可有效恢复大白兔模型伤是的行走功能.%Objective To investigate the replanting the skin under the microscope,the repair of rabbit model of anterior foot application effect of skin degloving injury.Methods 48 New Zealand rabbits,by means of simulation tool cutting avulsion,crush fore foot scene,resulting in the big white rabbit forefoot degloving injury combined with tibia,metatarsal,finger (toe) bone fracture,the establishment of rabbit animal model of the foot skin degloved injury,41 cases were successful,and the use of internal fixation of tibial fracture phalanx or repair of tendon rupture,under the microscope,the artery anastomosis front foot fractureand corresponding nerve,the dorsal skin and set off to the far side,through the direct anastomosis,anastomosed graft bridging method,such asby plane,arteriovenous anastomosis of dorsal,enable the skin to reset

  15. 儿童恒牙全脱出牙周组织预后的回顾性研究%Retrospective study about periodontal ligament healing of replanted permanent teeth in children

    Institute of Scientific and Technical Information of China (English)

    白洁; 赵玉鸣; 秦满

    2015-01-01

    Objective:To analyze the prognosis about periodontal ligament healing of replanted perma-nent teeth in children and to examine the associated factors.Methods: The sample consisted of 49 children with 61 avulsed permanent teeth, whose injuries had been managed in the period from 2000 to 2012.The clinical data of replanted teeth were collected, and the follow-up period was no less than 12 months .The factors were analyzed in relation to postoperative outcomes, classified as functional periodon-tal healing ( FH ) , infection-related ( inflammatory ) resorption ( IRR ) and replacement resorption ( RR) .Results:The functional healing rate was 23.0%, while replacement resorption rate was 72.1%. The replacement resorption ( ankylosis ) was usually observed earlier by clinical examination than by radiographic examination.86.0% (40/47) resorptive processes were diagnosed within the first year. Physiological storages, such as milk, saline and saliva were significantly better to periodontal ligament healing than nonphysiological storages, such as tap water and sterilizing solutions ( chloramine and alco-hol) .Functional healing was found significantly more frequent in canines and premolars.Conclusion:The factor significantly affecting periodontal ligament healing is storage medium.Replacement resorption is the most common type of root resorption.The replacement resorption diagnosis must combine the radio-graphic examination with the clinical examination.It is better to follow up more than 1 year after tooth re-plantation.%目的:对儿童恒牙全脱出后再植的病例进行回顾性研究,观察再植牙的牙周组织预后类型和各类根吸收出现的时间,分析影响再植牙牙周组织预后的可能因素。方法:对2000年至2012年在北京大学口腔医院就诊的儿童恒牙全脱出系统病历进行回顾性研究,要求观察期大于12个月,记录再植牙的预后和各类牙根吸收出现的时间,分析影响再植牙预后的相

  16. Morphometric and microscopic evaluation of the effect of gallium nitrate as a root canal dressing in rat teeth submitted to late replantation Avaliação morfométrica e microscópica do efeito do nitrato de gálio usado como curativo intracanal em dentes de ratos reimplantados tardiamente

    Directory of Open Access Journals (Sweden)

    Graziela Garrido Mori

    2006-12-01

    Full Text Available The purpose of this study was to test a gallium nitrate solution, a resorption inhibitor, employed as a root canal dressing in teeth submitted to late replantation. Thirty maxillary right central incisors of rats were avulsed and kept dry for thirty minutes. The teeth were instrumented and the root surfaces were treated with 1% hypochlorite solution followed by application of 2% sodium fluoride. Thereafter, the teeth were divided into two groups according to the root canal dressing: Group I, solution of gallium nitrate; and Group II, calcium hydroxide paste. The teeth were then replanted in their respective sockets. The animals were killed at 15, 30 and 60 days after replantation and the samples were processed for morphometric and microscopic analysis. The results demonstrated that the gallium nitrate solution and the calcium hydroxide paste limited the root resorption, yet they did not impair its occurrence. It may be concluded that gallium nitrate solution and calcium hydroxide paste demonstrated similar performance.Este trabalho tem como objetivo testar a solução de nitrato de gálio, um inibidor da reabsorção, como curativo intracanal para dentes reimplantados tardiamente. Trinta incisivos centrais superiores direitos de ratos foram avulsionados e mantidos a seco por trinta minutos. Todos os dentes tiveram os canais radiculares instrumentados e a superfície radicular tratada com hipoclorito de sódio a 1%, seguido de fluoreto de sódio a 2%. Após isso, os dentes foram divididos em dois grupos de acordo com a medicação intracanal: no grupo I, foi usada solução de nitrato de gálio e grupo II, pasta de hidróxido de cálcio. Todos os dentes foram, então, reimplantados em seus respectivos alvéolos. Passados 15, 30 e 60 dias do reimplante, os animais foram sacrificados e as peças obtidas, processadas em laboratório para análise microscópica e morfométrica. Os resultados mostraram que a solução de nitrato de gálio e a pasta de

  17. Application of evidence-based nursing for the prevention of vascular crisis after the operation of replantation of amputated finger%循证护理在预防断指再植术后血管危象中的应用

    Institute of Scientific and Technical Information of China (English)

    孟宪玲

    2009-01-01

    Objective To explore the effective intervention method to prevent vascular crisis after the operation of replantation of amputated finger with Application of evidenced based nursing. Methods 84 cases of replantation of amputated finger were randomly divided into two groups: observe group and compare group. Applicating usual nursing in compare group and evidence-based nursing in observe group. Results To search the cause and the effective intervention method of vascular crisis after the operation of replanlafion of ampu-tated finger with evidenced based nursing. Conclusion Applicatia of evidence-based nursing for the prevention of vascular crisis after the operation of replantation of amputated finger, so as to raise the survival rate of replanta-fion of amputated finger and promote the nursing quality.%目的 应用循证护理(EBM)探索断指再植术后血管危象的有效干预方法.方法 将84例断指再植患者随机分为观察组和对照组,各42例.对照组采用常规护理方法,观察组采用循证护理的方法实施血管危象的护理干预.结果 应用循证护理找出断指再植术后血管危象的原因及有效干预方法对断指再植术后的患者进行护理降低了血管危险的发生率.结论 循证护理在预防断指再植术后血管危象中的应用,使护理活动由被动变主动,有效地降低了血管危象的发生,提高了断指再植成活率,促进了护理质量的提高.

  18. Isolation, Identification and Interaction of Rhizosphere Microorganisms Involved in Peach Replant Diseases%与桃树再植病相关的根际微生物的分离鉴定及相互作用

    Institute of Scientific and Technical Information of China (English)

    邬瑞杰; 王兴华; 刘志民; 刘正坪; 胡昊; 马焕普

    2009-01-01

    [目的]研究桃树再植病与根际微生物的关系.[方法]以MФller氰化钾培养基为选择培养基进行桃根际微生物的筛选,采用16S rDNA序列分析并结合生物学特性对所获菌株进行鉴定,并通过温室盆栽试验对所获拮抗菌的生防效果进行初步观察.[结果]从桃根际土壤中分离筛选出3株能以扁桃苷为碳源产生氢化氰(HCN)的细菌(CN-X4、CN-X9、CN-X17)和3株分别能对上述细菌有不同抑制作用的放线菌(CN-G2、CN-G3、CN-G5).鉴定结果表明菌株CN-X4、CN-X17均为农杆菌属中的根癌农杆菌(Agrobacterium tumefaciens),但分属不同的变种;菌株CN-X9为假单胞杆菌(Pseudomonas sp.),菌株CN-G2和CN-G5分别为细黄链霉菌(Streptomycesmicroflavus)、淡紫灰链霉菌(Streptomyces lavendulae),菌株CN-G3可能是灰色链霉菌(Streptomyces griseus)的近缘种;拮抗菌盆栽生防效果显著.[结论]桃根际不仅存在能以扁桃苷为碳源并产生HCN的细菌而且同时存在与其相拮抗的耐氰放线菌,根际微生物区系平衡的破坏是导致再植病的关键因素之一.

  19. 根际微生物与植物再植病的发生发展关系%Association of rhizosphere soil microbiome with the occurrence and development of replant disease-A review

    Institute of Scientific and Technical Information of China (English)

    张蕾; 徐慧敏; 朱宝利

    2016-01-01

    植物再植病严重危害农作物的生长发育,形成原因复杂,最新的研究显示它与根际微生态的变化相关,其中主要涉及根际微生物菌群结构的变化.现代高通量测序技术的迅速推广使得根际微生物和再植病间关系成为新的研究热点;本文根据国内外植物再植病病因、根际土壤微生物多样性以及它们与植物生长发育关系等多方面的研究成果,综合分析植物再植病与根际微生物间的关系,以期从根际微生物种群动态变化的角度认识植物再植病的病因并为防治提供新的思路.

  20. 两种保存液对脱位牙再植术效果影响的实验研究%Experimental research into the influence of two kinds of storage media on the replantation of avulsed tooth

    Institute of Scientific and Technical Information of China (English)

    朱泽群; 陈铭清; 刘茜; 蔡琴; 王珏; 周红艳; 梅予锋

    2014-01-01

    目的:比较常温下脱脂牛奶与汉克斯平衡盐溶液(Hank′s balanced salt solution,HBSS)保存脱位牙对再植牙牙根愈合过程的影响。方法:48只6周龄 SPF级 Wistar雄性大鼠,随机抽取3只为空白对照,直接处死取材拍摄根尖 X线片,标本切片组织学观察;余45只随机分为3组,将上颌第一磨牙脱位后分别采用 HBSS、脱脂牛奶浸泡或干燥室温保存,30 min 后植回牙槽窝,术后1、3、7、14、21 d处死大鼠,拍摄根尖 X线片进行图像分析,标本切片进行组织学观察。结果:再植后各时间点牛奶组与 HBSS 组近中根阴影面积无统计学差异,皆小于干燥组(P<0.01);牛奶组根尖组织炎症反应较轻,根吸收少,根周修复类型与HBSS 基本相同。结论:脱脂牛奶与HBSS 在常温下均为良好的脱位牙体外保存液,可在普通人群中作为再植牙保存液推广使用。%Objective:To evaluate the effect of skimmed milk and Hank′s balanced salt solution(HBSS)as preservation medium on the root healing and root resorption of the avulsed tooth.Methods:3 out of 48 6-week-old SPF Wistar male rats were picked randomly as blank control,and the rest 45 rats were divided into three groups randomly:HBSS group,milk group and dry group.The bilateral maxillary first molars of rats in the three groups was extracted and replanted back into the sockets after being placed seperately in HB-SS,skimmed milk and in the air for 30 min right after extraction.The rats were sacrificed on day 1,day 3,day 7,day 14 and day 21 af-ter the operation.Then the maxillae were scanned with X-ray and the shadow areas around the mesial roots of maxillary first molars were measured with IPP software.After decalcification,the specimens were made into slices and stained with HE for histological obser-vation.Results:There was no statistically significant difference between milk group and HBSS group regarding the shadow area around

  1. Search for alternate hosts of the coconut Cape Saint Paul Wilt Disease pathogen

    Directory of Open Access Journals (Sweden)

    Yankey Egya Ndede

    2009-03-01

    Full Text Available Lethal Yellowing disease locally called Cape Saint Paul wilt disease (CSPWD is the bane of the coconut industry in Ghana and is caused by a phytoplasma. In Ghana, there are areas where the disease has re-infected re-plantings long after decimating all the palms in the area. This brings to the fore the possibility of alternate hosts in the spread of the disease because the pathogen is an obligate parasite. In this work, a number of plants were screened for their host status to the CSPWD pathogen. The presence of phytoplasmas in these plants was tested by polymerase chain reaction analysis using universal phytoplasma primers P1/P7 and CSPWD-specific primers G813/GAKSR. Although Desmodium adscendens tested positive to the CSPWD-specific primers, cloning and sequencing did not confirm it as an alternate host. The identification of alternate hosts will help us to evolve sound control strategies against the spread of the disease.

  2. Observation on changes of nailfold microcirculation and hemorheological indexes of severed limb replantation patients with postoperative infections%断肢再植术后感染患者甲襞微循环及血流指标的变化观察

    Institute of Scientific and Technical Information of China (English)

    张全英; 朱玉花; 李琼; 李中锋; 王丽娜

    2016-01-01

    目的:分析断肢再植术后感染患者甲襞微循环及血流变指标的变化,为断肢再植术后感染患者的诊治及预防控制提供依据。方法选取2012年1月-2015年9月收治的56例断肢再植术后感染患者为观察组,同时间段56例断肢再植术后未发生感染患者为对照组,将两组患者的甲襞微循环及血流变指标进行检测与比较,并比较观察组中浅层感染及深部感染者的检测结果。结果观察组甲襞微循环加权积分中的襻周积分、流态积分、管襻积分及总积分分别为(1.64±0.21)、(2.31±0.27)、(1.25±0.14)及(3.32±0.32),其均高于对照组(0.88±0.12)、(1.18±0.15)、(0.64±0.06)及(2.30±0.24),其他甲襞微循环指标及血流变指标也均高于对照组,且观察组中深部感染患者的检测结果高于浅层感染的患者,各个比较指标间差异均有统计学意义(P<0.05)。结论断肢再植术后感染患者甲襞微循环及血流变指标均较高,且浅部感染与深部感染患者的检测结果也存在明显差异,因此应重视对此类患者进行微循环状态的改善。%OBJECTIVE To investigate the changes of nailfold microcirculation and hemorheological indexes of se‐vered limb replantation patients with postoperative infections so as to provide guidance for clinical diagnosis ,treat‐ment ,and prevention of the postoperative infections in the severed limb replantation patients .METHODS Totally 56 patients who underwent the replantation of severed limb and had postoperative infections from Jan 2012 to Sep 2015 were recruited as the observation group ,meanwhile ,56 patients who underwent the replantation of severed limb but did not have postoperative infections were set as the control group ,then the nailfold microcirculation and hemorheological indexes were detected and compared between the two groups of patients ,and the test

  3. Application of laminoplasty of pedicled complex replantation on reconstruction of spinal canal at excision of intraspinal tumor%带蒂椎板复合体回植钛网固定在椎管内肿瘤治疗中的应用

    Institute of Scientific and Technical Information of China (English)

    李同相; 肖睿; 官清; 李兴波; 魏书一

    2012-01-01

    目的 探讨带蒂椎板复合体回植、钛网固定,在椎管内肿瘤切除术中椎管重建的应用价值.方法 对13例椎管内肿瘤患者保留双侧关节突关节,根据椎管内肿瘤的大小,采用磨钻或微型咬骨钳沿双侧关节突内侧缘打开一个或多个椎板,切断一端棘上和棘间韧带,将椎板复合体翻转,椎管内肿瘤切除后再将其原位回植,钛网固定,重建椎管完整性和脊柱的稳定性.结果 13例椎管内肿瘤全部成功切除,切除椎板数2~4个,平均(2.5±0.5)个.1例因粘连致硬脊膜破损,1例哑铃型神经鞘瘤术后6个月复发.随访12~27个月,平均(13±0.5)个月,所有病例回植物稳定,无塌陷及椎管狭窄,术后肢体瘫痪Frankel分级均有不同程度提高.结论 椎管内肿瘤术中将带蒂椎板复合体翻转,术后用钛网回植固定,方法简便、安全,有利于保持椎管的完整性及脊柱的稳定性.%Objective To study the value of laminoplasty of pedicled complex replantation on reconstruction of spinal canal at excision of intraspinal tumor. Methods 13 patients with intraspinal canal tumors were treated in our hospital. Each case was reserved bilateral facet joint, one or several vertebral lamina were cut by burr drill or micro rongeur a-long the inner edge of bilateral facet joint, Superspinal and interspinal ligaments of one side were cut, then pedicelar vertebral lamina complex was retroflexed and intraspinal canal was exposured. After resection of the tumor, pedicelar verte-bral lamina complex was replanted and titanic mesh was fixated to reconstruct the integrity of vertebral canal and the sta-bility of spinal column. Results The tumors of 13 cases were totally resected, 2-4(2. 5±0. 5 on average) lamina were removed. 1 case of dura mater was injured for the adhesion, 1 case Dumbbell Schwannoma was recurred after 6 months. The patients were followed up for 12 to 27 months(13±0. 5 months on average),during which no collapse of the

  4. Application of Laminoplasty of Pedicled Complex Replantation on Reconstruction of Spinal Canal at Degenerative Lumbar Spinal Stenosis%带蒂椎板复合体回植钛网固定在退变性腰椎管狭窄治疗中的应用

    Institute of Scientific and Technical Information of China (English)

    肖睿; 李同相; 官清; 李兴波; 魏书一

    2015-01-01

    Objective To investigate the therapeutic effects of laminoplasty of pedicled complex replantation on recon-struction of spinal canal at lumbar spinal stenosis. Methods The involved segments were determinged by symptoms, clinical fea-tures and radiographic at the initial examination. 15patients with lumbar spinal stenosis were treated in our hospital. Each case was reserved bilateral facet joint,one or several vertebral lamina were cut by burr drill or micro-rongeur along the inner edge of bilateral facet joint,Superspinal and interspinal ligaments of one side were cut,then pedicelar vertehral lamina complex was retroflexed and intraspinal canal was exposured. After Lumbar spinal canal decompression,pedicelar vertebral lamina complex was replanted and ti-tanic mesh was fixated to reconstruct the integrity of vertebral canal and the stability of spinal column. Application VAS and ODI scoring method for subjective and objective evaluation of clinical curative effect before and after operation. Results The patients were followed up for 12 to 28 months[(13 ± 0. 5) months on average],during which no collapse of the replanted tissues or spinal canal stenosis occurred. Postoperative patients VAS and ODI score significantly higher than before,the difference was statistically sig-nificant(P<0. 05). Conclusion Retroflexing pedicelar vertebral plate complex and fixating with titanium plate in the lumbar spi-nal stenosis is simple,safe. The spinal column active naturelv without limit postoperatively,the technique can maintain the spinal col-umn good stability and protect the spinal column from degradation.%目的:探讨带蒂椎板复合体回植、钛网固定行椎管成形术治疗退行性腰椎管狭窄症的临床疗效。方法根据临床表现和影像学检查确定减压部位,对15例退行性腰椎管狭窄患者保留双侧关节突关节,采用磨钻或微型咬骨钳沿双侧关节突内侧缘打开一个或多个椎板,切断一端棘上和棘间韧

  5. The Effects of Antagonistic Actinomycetes G19 on Microbial Diversity in Replanted Peach Rhizosphere%拮抗放线菌G19对模拟再植毛桃根际微生物多样性的影响

    Institute of Scientific and Technical Information of China (English)

    邸宁; 刘志民; 马焕普

    2011-01-01

    为了了解不同处理对微生物多样性变化的影响,试验采用Biolog技术对施用拮抗放线菌发酵液后的毛桃根际微生物的多样性进行了分析,结果表明:施放线菌G-19后,其根际细菌和放线菌数量增加,真菌数量明显减少,与正常土的变化趋势相似;再植土则相反,真菌数量大幅上升,细菌数量下降.微生物代谢活性及微生物群落多样性指数显示施用了放线菌G-19的根际微生物也是最丰富和稳定的,毛桃幼苗的生长也以施放线菌G-19发酵液的效果最好,这说明拮抗放线菌G-19有改善桃再植土壤微生态的作用.%The aim was to compare the difference in microbial diversity of different treatments. In this study, microbial diversity of peach rhizosphere which fermented antagonistic actinomycetes was measured by Biolog Eco plate facilities. The results showed that the number of bacteria and actinomycetes in peach rhizosphere increased significantly and the number of fungi decreased. That was similar to the normal soil. By contrast, the number of fungi increased significantly and the number of bacteria and actinomycetes decreased in replant soil. Microbial metabolic activity and microbial community diversity index application of actinomycetes G19 in rhizosphere microorganisms was the most abundant and stable. Seedling growth of peach was the best after strains G19 fermentation broth treatment. It indicated that antagonistic actinomycetes G19 could improve the ecological environment of the soil in replant peach rhizosphere.

  6. 桩钉辅助玻璃离子粘结固定冠根纵折后牙再植治疗临床观察%Clinical observation on replantation of vertical fractured posterior teeth after bonding with glass ionomer cement and fixation with metal post

    Institute of Scientific and Technical Information of China (English)

    黎石坚; 陈燕; 陆兆威; 罗菊芬; 李民东

    2012-01-01

    Objective To investigate the therapeutic results on replantation of vertical fractured posterior teeth after bonding with glass ionomer cement and fixation with metal post. Methods A total of 40 vertical fractured posterior teeth were treated by extraction,root canal therapy,bonding with glass ionomer cement.fixation with metal post, replantation and coronal restoration. 36 of the 40 posterior teeth were completely followed up for 2 years and evaluated. Results Among 36 vertical fractured posterior teeth observed,the the successful reserved rate of 6 months was 100.00% (36/36),one year was 88.89% (32/36),two years was 80.56% (29/36) There were statistical significant differences of the reserved rate in difference period after therapy, the reserved rate became lower with observation time became longer. Conclusion The therapeutic results were satisfied with a 2-year reserved rate, and the method can be worth of clinical application.%目的:对桩钉辅助玻璃离子粘结固定冠根纵折的后牙行再植术并行冠修复的临床效果进行观察、评价.方法:选择40例牙体相对完好、牙周情况良好的纵裂的后牙,拔牙后即刻体外完成根管治疗,用玻璃离子粘固剂粘结并复位,冠部横向钻通,插入并粘结根管桩钉辅助固定,再植入牙槽窝,2个月后行全冠或连冠修复,随访2年,观察疗效.结果:除失访4例外,6个月的成功保存率为100.00%(36/36),1年的保存率为88.89%(32/36),2年的保存率为80.56%(29/36),成功率随术后时间延长而下降.结论:正确选择适应证,对桩钉辅助玻璃离子粘结固定冠根纵折的后牙再植治疗,可获得一定的效果满意,为临床保存治疗提供多一种选择.

  7. Delayed tooth replantation after root surface treatment with sodium hypochlorite and sodium fluoride: histomorphometric analysis in rats Reimplante dentário tardio após o tratamento da superfície radicular com hipoclorito de sódio e fluoreto de sódio: análise histomorfométrica em ratos

    Directory of Open Access Journals (Sweden)

    André Dotto Sottovia

    2006-04-01

    Full Text Available In cases of delayed tooth replantation, non-vital periodontal ligament remnants have been removed with sodium hypochlorite in an attempt to control root resorption. Nevertheless, reports of its irritating potential in contact with the alveolar connective tissue have been described. Therefore, this study evaluated the healing process on delayed replantation of rat teeth, after periodontal ligament removal by different treatment modalities. Twenty-four rats, assigned to 3 groups (n=8, had their upper right incisor extracted and left on the workbench for desiccation during 60 min. Afterwards, the teeth in group I were immersed in saline for 2 min. In group II, root surfaces were scrubbed with gauze soaked in saline for 2 min; and in group III, scrubbing was done with gauze soaked in 1% sodium hypochlorite solution. Thereafter, root surfaces were etched with 37% phosphoric acid and immersed in 2% acidulate-phosphate sodium fluoride solution, at pH 5.5. Root canals were filled with a calcium hydroxide-based paste and the teeth were replanted. The animals were sacrificed 60 days postoperatively and the pieces containing the replanted teeth were processed and paraffin- embedded. Semi-serial transversally sections were obtained from the middle third of the root and stained with hematoxylin and eosin for histomorphometric analysis. Data were analyzed statistically using Kruskal-Wallis and Dunn's tests. The results showed that root structure and cementum extension were more affected by resorption in group III (pEm reimplante dentário tardio, o ligamento periodontal desvitalizado tem sido removido empregando-se o hipoclorito de sódio, buscando o controle da reabsorção radicular. Relatos de efeito irritante no tecido conjuntivo alveolar após o seu uso, têm sido descritos. Isso justificou a realização deste trabalho buscando minimizar esse inconveniente. Para isso 24 ratos, divididos em 3 grupos de 8 animais, tiveram o incisivo superior direito extra

  8. 瘤段截骨加热70℃蒸馏水中15 min:灭活回植治疗腓骨近端骨肿瘤%Replantation of inactivated tumor segment boiled in 70℃ distilled water for 15 minutes in the treatment of proximal fibular tumors

    Institute of Scientific and Technical Information of China (English)

    包毅敏; 张国梁; 杜佩晋; 王跃文

    2014-01-01

    BACKGROUND:Apart from a complete resection of tumor tissues, the therapeutic goal for bone tumors is to maximize the repair and restoration of tissue defects and damaged functions. Autologous inactivated bone graft is of practical value for transplantation and reconstruction. OBJECTIVE:To investigate the effect of improved Malawer method combined with replantation of inactivated tumor segment in the treatment of proximal fibular tumors. METHODS: Since 2007, five patients with proximal fibular tumors (six sides) were admitted in the Affiliated Hospital of Inner Mongolia Medical University. These five patients were subjected to distal femoral amputation, intralesional curettage and bone grafting, upper fibular osteotomy + tumor segment heating (boiling in 70℃ distiled water for 15 minutes) + inactivated bone replantation. Therapeutic effects were folowed. RESULTS AND CONCLUSION: One case of amputation had no recurrence and systemic metastasis during 4 years of folow-up; one case of intralesional curettage and bone grafting relapsed 1 year after operation; three cases of upper fibular osteotomy + tumor segment heating + inactivated bone replantation folowed for 5 months recovered walking function and exhibited good healing of the outer structure of the knee, showing non-healing of inactivated tumor segment, non-remarkable calus formation, no local tumor recurrence, no loosening of internal fixation, and inactivated bone without fracture and absorption. These results confirmed that the tumor curettage and amputation both have obvious limitations; based on Malawer method, the replantation of inactive tumor segment can better ensure the structure integrity of the lower leg and in suit reconstruct the lateral biceps femoris tendon and the lateral colateral ligament, but geneticaly the revascularization and healing of inactivated bones wil be difficult and slow with temperature increases, and therefore the period of postoperative brace protection should be relatively

  9. Heart Disease

    Science.gov (United States)

    ... type of heart disease you have. Symptoms of heart disease in your blood vessels (atherosclerotic disease) Cardiovascular disease ... can sometimes be found early with regular evaluations. Heart disease symptoms caused by abnormal heartbeats (heart arrhythmias) A ...

  10. Efeito do alopurinol e terapia com oxigênio hiperbárico em modelo de reimplante de membro após isquemia quente em ratos Effect of allopurinol and hyperbaric oxygen therapy in a limb replantation model after warm ischemia in rats

    Directory of Open Access Journals (Sweden)

    Marcelo Sacramento Cunha

    2005-04-01

    Full Text Available OBJETIVO: A isquemia prolongada leva a alterações na microcirculação tecidual e liberação de radicais livres do oxigênio conhecidas como fenômeno de não reperfusão. Foi testado um modelo experimental de reimplante de membro após isquemia quente e os efeitos do fármaco alopurinol e da terapia com oxigênio hiperbárico. MÉTODO: Foram realizadas amputações com preservação dos vasos e nervos dos membros posteriores direitos em 95 ratos. Os grupos modelos M1, M2, M3, M4 e M5 foram submetidos à isquemia quente de 0, 2, 4, 6 e 8 horas. As taxas de viabilidade dos membros isquêmicos após sete dias de avaliação foram 100%, 80%, 63,6%, 50% e 20%. Os grupos experimentais E1 e E2 foram tratados, respectivamente, com alopurinol e terapia com oxigênio hiperbárico após isquemia de 6 horas. As taxas de viabilidade foram 70% e 30%. Os resultados foram analisados estatisticamente pelo teste do Qui-quadrado. RESULTADOS: Os grupos M1, M2, M3, M4 e M5 foram estatisticamente diferentes entre si exceto os grupos M3 e M4. E1 resultou em uma viabilidade de membros maior que M4 e E2 resultou em uma viabilidade de membros menor que M4(resultados estatisticamente significantes. CONCLUSÕES: Os resultados sugerem que a administração do alopurinol após isquemia do membro por 6 horas aumenta a taxa de viabilidade dos membros isquêmicos, e a terapia com oxigênio hiperbárico diminuiu a viabilidade dos membros isquêmicos.BACKGROUND: Prolonged ischemia leads to alterations in tissue microcirculation and oxygen free radicals production. This event is called no reflow phenomenon and its management is a challenge to the surgeon dealing with replantation. It was tested a replantation model after warm ischemia in rats and the effectiveness of allopurinol and hyperbaric oxigen therapy. METHODS: Amputation with preservation of vessels and nerves of the right hind limb was proceeded in 95 rats. The groups M1, M2, M3, M4 and M5 were submitted to 0, 2, 4, 6

  11. Effect of self-efficacy intervention on the self-management behavior of patients with replantation of severed fingers%自我效能干预对断指再植患者自我管理行为的影响

    Institute of Scientific and Technical Information of China (English)

    王桂芝; 王维维

    2012-01-01

    Objective: To investigate the effect of self - efficacy intervention on the self - management behavior of patients with replantation of severed fingers. Methods: 60 patients were randomly divided into observation and control groups ( 30 cases in each group ). The conventional microsurgical nursing care was implemented in the control group, including observation on the blood supply of limbs, prohibition of active or passive smoking, immobilization of the affected limb, etc. ; the patients in the observation group were given intervention on self - management behavior in the light of self - efficacy theory based on the conventional nursing care, including incentives, social support, alternative experience, goal setting and avoiding negative stimulus. Results: There were statistically significant differences in the comparison of the self - efficacy and self - management behavior scores between the two groups before and after the intervention, the difference in the comparison of the difference value of score of each factor of self - management behavior was statistically significant between the two groups before and after the intervention ( P <0. 05 ). Conclusion: The self - efficacy intervention can effectively improve self - management behavior of patients with replantation of severed fingers and reduce the incidence of vascular crisis.%目的:探讨自我效能干预对断指再植患者自我管理行为的影响.方法:将60例患者随机分为观察组和对照组各30例.对照组给予断指再植术后显微外科常规护理,包括肢体血运观察、禁止主动或被动吸烟、患肢制动等;观察组在常规护理基础上,运用自我效能理论对患者进行自我管理行为的干预,包括激励、社会支持、替代经验、目标设置、负性刺激回避.结果:两组患者干预前后自我效能和自我管理行为得分差值比较差异有统计学意义,且两组患者干预前后自我管理行为各项因子分差值比

  12. Surgical technique of alcohol-inactivated autograft replantation with articulation preservation in management of malignant bone tumor around knee%保留关节的瘤段切除酒精灭活再植术在膝关节周围恶性骨肿瘤治疗中的应用

    Institute of Scientific and Technical Information of China (English)

    许宋锋; 于秀淳; 徐明; 刘晓平; 宋若先; 付志厚

    2012-01-01

    Objective To evaluate the clinical outcome of alcohol-inactivated autograft replantation with articulation preservation in management of malignant bone tumor around knee, and explain the surgical technique. Methods Seven patients were treated with alcohol-inactivated autograft replantation with articulation preservation from January 2010 to November 2011, including six males and one female, with the median age of 21 years (16 to 23 years). Five neoplasms were located in left distal femur, one in right distal femur, and one in left proximal fibula involving tibia. According to Enneking tumor staging, six patients were identified as stage ⅡB,one as stage Ⅲ. Six patients were diagnosed as osteosarcoma and one as non-Hodgkin' s lymphoma. The postoperative results were evaluated by MSTS limb function score system and ISOLS composite graft evaluation method. Combining the operation process, surgical technique and perioperative key points were explained. Results All seven patients achieved primary healing. With the mean follow-up time of 17 months (8 to 24 months), there was no infection, recurrence, loosening or limb length inequality. The mean ISOLS graft score was 31 (87% ) (range 30 -34). The mean MSTS function score was 25 (84%) (range 22-25 ). Conclusions These results suggest that alcohol-inactivated autograft replantation with articulation preservation could improve the short-term limb function, avoiding complications of prosthesis. With strict indications, good surgical technique and perioperative managements, fine clinical outcome could be achieved. It is relatively economic- applicable for patients and could be an option among surgical treatments. The clinical outcomes in long-term still need to be investigated.%目的 探讨保留关节的酒精灭活骨再植术在膝关节周围恶性骨肿瘤治疗中的应用,并阐述其手术技术要点.方法 2010年1月至2011年5月采用保留关节的瘤段切除酒精灭活再植术治疗

  13. Lung disease

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000066.htm Lung disease To use the sharing features on this page, ... fibrosis and sarcoidosis are examples of lung tissue disease. Lung circulation diseases -- These diseases affect the blood vessels ...

  14. Gaucher disease

    OpenAIRE

    POSPÍŠILOVÁ, Iva

    2012-01-01

    This thesis is about the disease called Gaucher disease, or Morbus Gaucher. There is described the history of the disease, various forms of disease, effect of bones, visceral organs, hematological changes, changes in metabolism etc.; differential diagnosis, diagnosis and therapy.

  15. Assessment of Basal Stem Rot Disease Distribution in Palm Oil Plantation Using Geographical Information System

    Directory of Open Access Journals (Sweden)

    Tengku Mohd Azahar

    2014-12-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE The concurrent advances in global positioning systems (GPS and Geographical Information Systems (GIS techniques have provided powerful analysis tools for precision agriculture. This study will focus on how Geographical Information System (GIS can help to assess the distribution Basal Stem Rot Diseases (BSR on oil palm plantation. Basal Stem Rot (BSR is caused by Ganoderma Boninense, and it is the most serious disease for oil palm trees in Malaysia. The fungus infects oil palm trees, initially causing yield loss and finally killing the trees. Various factors were previously reported to influence incidence of BSR, such as previous crops, techniques for replanting, types of soils, density and the age of trees. At present, effective and sustainable management strategies to control BSR are hampered mainly by a lack of understanding of mechanisms of disease establishment, development and spread. The study aims to apply spatial analysis methods to investigate the behaviours of BSR. Data for analysis were obtained from oil palm plantation at Teluk Intan, Perak, Malaysia. /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";}

  16. 依达拉奉对深低温冻存大鼠断肢再植后缺血再灌注损伤骨骼肌细胞膜及线粒体的保护效应%Protective influence of edaravone on cellular membrane and mitochondria of replanted rat extremities following ischemia/reperfusion injury due to cryopreservation and rewarming

    Institute of Scientific and Technical Information of China (English)

    段永壮; 钟世镇; 王增涛; 徐达传; 丁自海; 付庆林; 郝丽文; 何波

    2007-01-01

    肌缺血再灌注损伤,对骨骼肌细胞膜及线粒体有保护作用.其作用可能与依达拉奉直接抑制羟自由基、提高骨骼肌超氧化物歧化酶活性、减少丙二醛的产生,使细胞进行正常的氧化磷酸化有关.%BACKGROUND: A lot of important organs are worthless for clinical application because they are hard to store for a long time. In addition, tissues or organs which are dealt with cryopreservation also attack ischemia/reperfusion injury with the recovery of blood flow; especially, skeletal muscle is the most involved tissue.OBJECTIVE: To observe the protective influence of edaravone on cellular membrane and mitochondria of replanted rat extremities following ischemia/reperfusion injury due to cryopreservation and rewarming.DESIGN: Randomized contrast animal study.SETTING: Basic Medical College of Southern Medical University; Department of Hand and Foot Surgery, Shandong Provincial Hospital.MATERIALS: The experiment was carried out in the Cryopreservation Laboratory, Shandong Provincial Hospital from April to November 2006. A total of 36 healthy adult male Wistar rats were provided by Experimental Animal Center of Medical College of Shandong University. All rats were randomly divided into control group, cryopreservation group and edaravone group with 12 in each group.METHODS: Femoral artery and vein of rats in control group were exposured, but extremities were not blocked. Rats in other two groups were used to establish ischemia/reperfusion injury models of replanted extremities. Before cryopreservation, their right hindlimbs were cut off and maintained in liquid nitrogen container for 1 month. After the operation mentioned above, the broken limbs were rewarmed, perfused with routine eluant and replanted. Four hours later, blood supply of extremities was recirculated and the samples were selected. Eluant in edaravone group contained 0.5 mg/kg edaravone. Samples of skeletal muscle were selected at the same time point to

  17. Hashimoto's Disease

    Science.gov (United States)

    ... is Hashimoto’s disease? Hashimoto’s disease, also called chronic lymphocytic thyroiditis or autoimmune thyroiditis, is an autoimmune disease. An ... Points to Remember • Hashimoto’s disease, also called chronic lymphocytic thyroiditis or autoimmune thyroiditis, is an autoimmune disease. • Hashimoto’s ...

  18. Kawasaki Disease

    Science.gov (United States)

    Kawasaki disease is a rare childhood disease. It makes the walls of the blood vessels in the ... veins, and capillaries. No one knows what causes Kawasaki disease. Symptoms include High fever that lasts longer ...

  19. Alzheimer Disease

    Science.gov (United States)

    ... CPR: A Real Lifesaver Kids Talk About: Coaches Alzheimer Disease KidsHealth > For Kids > Alzheimer Disease Print A A ... slow it down. When Someone You Love Has Alzheimer Disease You might feel sad or angry — or both — ...

  20. Crohn's Disease

    Science.gov (United States)

    Crohn's disease causes inflammation of the digestive system. It is one of a group of diseases called inflammatory ... small intestine called the ileum. The cause of Crohn's disease is unknown. It may be due to an ...

  1. Crohn disease

    Science.gov (United States)

    ... from doing your everyday activities. You have side effects from medicines you are taking for your condition. Alternative Names Crohn's disease; Inflammatory bowel disease - Crohn's disease; Regional enteritis; Ileitis; ...

  2. Meniere's Disease

    Science.gov (United States)

    ... Meniere's disease can affect your social life, your productivity and the overall quality of your life. Learn ... www.mayoclinic.org/diseases-conditions/menieres-disease/basics/definition/CON-20028251 . Mayo Clinic Footer Legal Conditions and ...

  3. Kawasaki disease

    Science.gov (United States)

    ... lymph node syndrome; Infantile polyarteritis Images Kawasaki's disease - edema of the hand Kawasaki's disease, peeling of the fingertips References Dominguez SR, Anderson MS. Advances in the treatment of Kawasaki disease. Curr Opin Pediatr . 2013;25( ...

  4. Gaucher's Disease

    Science.gov (United States)

    ... of developing the most common variety of Gaucher's disease. Gaucher's disease may increase the risk of: Growth delays ... illness can be difficult, but having a rare disease like Gaucher's may be even harder. Few people know about ...

  5. Huntington's Disease

    Science.gov (United States)

    Huntington's disease (HD) is an inherited disease that causes certain nerve cells in the brain to waste ... express emotions. If one of your parents has Huntington's disease, you have a 50 percent chance of ...

  6. Sever's Disease

    Science.gov (United States)

    ... take place on hard surfaces, such as track, basketball, soccer, and gymnastics. Sever's disease also can result ... diagnosing Sever's disease, some doctors order them to rule out other problems, such as fractures. Sever's disease ...

  7. Celiac Disease

    Science.gov (United States)

    ... digestive problems called inflammatory bowel disease (IBD) or lactose intolerance . And in some cases, a kid won't ... for Kids With Celiac Disease Inflammatory Bowel Disease Lactose Intolerance Are Your Bowels Moving? Indigestion Nut and Peanut ...

  8. Ribbing disease

    Directory of Open Access Journals (Sweden)

    Mukkada Philson

    2010-01-01

    Full Text Available Ribbing disease is a rare sclerosing dysplasia that involves long tubular bones, especially the tibia and femur. It occurs after puberty and is reported to be more common in women. In this article we describe how Ribbing disease can be differentiated from diseases like Engelmann-Camurati disease, van Buchem disease, Erdheim-Chester disease, osteoid osteoma, chronic osteomyelitis, stress fracture, etc.

  9. Bladder Diseases

    Science.gov (United States)

    ... frequent, urgent urination Bladder cancer Doctors diagnose bladder diseases using different tests. These include urine tests, x- ... National Institute of Diabetes and Digestive and Kidney Diseases

  10. Coconut lethal yellowing diseases: a phytoplasma threat to palms of global economic and social significance

    Directory of Open Access Journals (Sweden)

    Gurr M Geoff

    2016-10-01

    Full Text Available The recent discovery of Bogia Coconut Syndrome in Papua New Guinea is the first report of a lethal yellowing disease (LYD in Oceania. Numerous outbreaks of LYDs of coconut have been recorded in the Caribbean and Africa since the late 19th century and have caused the death of millions of palms across several continents during the 20th century. Despite the severity of economic losses, it was only in the 1970s that the causes of LYDs were identified as phytoplasmas, a group of insect-transmitted bacteria associated with diseases in many other economically important crop species. Since the development of polymerase chain reaction (PCR technology, knowledge of LYDs epidemiology, ecology and vectors has grown rapidly. There is no economically viable treatment for LYDs and vector-based management is hampered by the fact that vectors have been positively identified in very few cases despite many attempted transmission trials. Some varieties and hybrids of coconut palm are known to be less susceptible to LYD but none are completely resistant. Optimal and current management of LYD is through strict quarantine, prompt detection and destruction of symptomatic palms, and replanting with less susceptible varieties or crop species. Advances in technology such as loop mediated isothermal amplification (LAMP for detection and tracking of phytoplasma DNA in plants and insects, remote sensing for identifying symptomatic palms, and the advent of clustered regularly interspaced short palindromic repeats (CRISPR-based tools for gene editing and plant breeding are likely to allow rapid progress in taxonomy as well as understanding and managing LYD phytoplasma pathosystems.

  11. Metabolic composition of apple rootstock rhizodeposits differs in a genotype-specific manner and affects growth of subsequent plantings

    Science.gov (United States)

    The percolated rhizodeposit composition and quantity of 4 apple rootstock genotypes grown in sand was examined via liquid chromatography mass spectrometry time-of-flight, specifically contrasting the rhizodeposits of apple replant disease susceptible genotypes (M26, M9Nic29) with apple replant disea...

  12. Totally impermeable film (TIF) reduces emissions in perennial crop fumigation

    Science.gov (United States)

    Orchard/vineyard replanting for fruit trees, nut trees, and grapevines in many situations still depends on soil fumigation for control of soil-borne pests and replanting diseases in California. Perennial tree and grapevine nurseries also rely heavily on soil fumigation to meet the state’s requiremen...

  13. Fifth Disease

    Science.gov (United States)

    ... roseola. Fifth disease is sometimes called “slapped cheek disease.” The illness’s bright red rash on the face looks like ... disease Most children and adults who get fifth disease experience only mild illness. They recover completely and have no complications. But ...

  14. Heart Diseases

    Science.gov (United States)

    ... you're like most people, you think that heart disease is a problem for others. But heart disease is the number one killer in the U.S. ... of disability. There are many different forms of heart disease. The most common cause of heart disease is ...

  15. Whipple's Disease

    Science.gov (United States)

    ... more common conditions with similar symptoms, including inflammatory rheumatic disease—characterized by inflammation and loss of function in ... Management Liver Disease Urologic Diseases Endocrine Diseases Diet & Nutrition Blood Diseases Diagnostic Tests La información de la salud en ...

  16. Bacteriophage PRD1 batch experiments to study attachment, detachment and inactivation processes

    NARCIS (Netherlands)

    Sadeghi, G.; Schijven, J.F.; Behrends, T.; Hassanizadeh, S.M.; van Genuchten, M.T.

    2013-01-01

    Knowledge of virus removal in subsurface environments is pivotal for assessing the risk of viral contamination of water resources and developing appropriate protection measures. Columns packed with sand are frequently used to quantify attachment, detachment and inactivation rates of viruses. Since

  17. XTAT: A New Multilevel-Multiline Polarized Radiative Transfer Code with PRD

    Science.gov (United States)

    Bommier, V.

    2014-10-01

    This work is intended to the interpretation of the so-called "Second Solar Spectrum" (Stenflo 1996), which is the spectrum of the linear polarization formed by scattering and observed close to the solar internal limb. The lines are also optically thick, and the problem is to solve in a coherent manner, the statistical equilibrium of the atomic density matrix and the polarized radiative transfer in the atmosphere. Following Belluzzi & Landi Degl'Innocenti (2009), 30 % of the solar visible line linear polarization profiles display the M-type shape typical of coherent scattering effect in the far wings. A new theory including both coherent (Rayleigh) and resonant scatterings was developed by Bommier (1997a,b). Raman scattering was later added (Bommier 1999, SPW2). In this theory, which is straightly derived from the Schrödinger equation for the atomic density matrix, the radiative line broadening appears as a non-Markovian process of atom-photon interaction. The collisional broadening is included. The Rayleigh (Raman) scattering appears as an additional term in the emissivity from the fourth order of the atom-photon interaction perturbation development. The development is pursued and finally summed up, leading to a non-perturbative final result. In this formalism, the use of redistribution functions is avoided. The published formalism was limited to the two-level atom without lower level alignment. But most of the solar lines are more complex. We will present how the theory has to be complemented for multi-level atom modeling, including lower level alignment. The role of the collisions as balancing coherent and resonant scatterings is fully taken into account. Progress report will be given about the development of a new code for the numerical iterative solution of the statistical equilibrium and polarized radiative transfer equations, for multi-level atoms and their multi-line spectrum. Fine and hyperfine structures, and Hanle, Kemp (Kemp et al. 1984), Zeeman, incomplete Paschen-Back effects, are included. Doppler redistribution is fully taken into account, by solving the statistical equilibrium for each velocity class of the atoms. In the presentation, a particular attention will be devoted to the depolarizing collisions and their rate estimation.

  18. Addison disease

    Science.gov (United States)

    ... amounts of some or all of its hormones ( hypopituitarism ) Autoimmune disorder that affects the nerves and the ... disease) Dermatitis herpetiformis Diabetes Graves disease Hyperthyroidism Hypoparathyroidism Hypopituitarism Immune response Myasthenia gravis Ovarian hypofunction Pernicious anemia ...

  19. Fifth disease

    Science.gov (United States)

    Parvovirus B19; Erythema infectiosum; Slapped cheek rash ... Fifth disease is caused by human parvovirus B19. It often affects preschoolers or school-age children during the spring. The disease spreads through the fluids in the nose and ...

  20. Rh Disease

    Science.gov (United States)

    ... Loss > Birth defects & other health conditions > Rh disease Rh disease E-mail to a friend Please fill ... Rh-negative with a blood test. What is Rh factor? Rh factor is a protein that’s found ...

  1. Binswanger's Disease

    Science.gov (United States)

    ... Craniosynostosis Information Page Creutzfeldt-Jakob Disease Information Page Cushing's Syndrome Information Page Dandy-Walker Syndrome Information Page Deep Brain Stimulation for Parkinson's Disease Information Page Dementia Information ...

  2. Batten Disease

    Science.gov (United States)

    ... Craniosynostosis Information Page Creutzfeldt-Jakob Disease Information Page Cushing's Syndrome Information Page Dandy-Walker Syndrome Information Page Deep Brain Stimulation for Parkinson's Disease Information Page Dementia Information ...

  3. Behcet's Disease

    Science.gov (United States)

    ... Craniosynostosis Information Page Creutzfeldt-Jakob Disease Information Page Cushing's Syndrome Information Page Dandy-Walker Syndrome Information Page Deep Brain Stimulation for Parkinson's Disease Information Page Dementia Information ...

  4. Krabbe Disease

    Science.gov (United States)

    ... Craniosynostosis Information Page Creutzfeldt-Jakob Disease Information Page Cushing's Syndrome Information Page Dandy-Walker Syndrome Information Page Deep Brain Stimulation for Parkinson's Disease Information Page Dementia Information ...

  5. Crohn's Disease

    Science.gov (United States)

    ... prognosis of Crohn's disease in adults. http://www.uptodate.com/home. Accessed June 2, 2014. Smoking and ... cancer surveillance in inflammatory bowel disease. http://www.uptodate.com/home. Accessed June 9, 2014. Inflammatory bowel ...

  6. Addison Disease

    Science.gov (United States)

    ... your blood pressure and water and salt balance. Addison disease happens if the adrenal glands don't make ... A problem with your immune system usually causes Addison disease. The immune system mistakenly attacks your own tissues, ...

  7. Liver Diseases

    Science.gov (United States)

    Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons. There are many kinds of liver diseases: Diseases caused by viruses, such as hepatitis ...

  8. Valve Disease

    Science.gov (United States)

    ... heart valves, valve insufficiency, valve regurgitation, valve stenosis, valvular heart disease Every time your heart beats, blood flows into, ... removed from the market after being linked to heart valve disease. An infection in the lining of the heart's ...

  9. Wilson Disease

    Science.gov (United States)

    Wilson disease is a rare inherited disorder that prevents your body from getting rid of extra copper. You ... extra copper into bile, a digestive fluid. With Wilson disease, the copper builds up in your liver, and ...

  10. Gaucher disease

    Science.gov (United States)

    ... doesn't have the disease is called a silent carrier. The lack of the glucocerebrosidase enzyme causes ... liver Fatigue Heart valve problems Lung disease (rare) Seizures Severe swelling at birth Skin changes

  11. Legionnaire disease

    Science.gov (United States)

    ... features on this page, please enable JavaScript. Legionnaire disease is an infection of the lungs and airways. It is caused by Legionella bacteria. Causes The bacteria that cause Legionnaire disease have ...

  12. Parkinson's Disease

    Science.gov (United States)

    ... messages it needs to move normally. continue What Causes Parkinson's Disease? Experts agree that low dopamine levels in ... or other chemicals. No one knows the exact cause of Parkinson's disease, but we do know that it has ...

  13. Fabry Disease

    Science.gov (United States)

    ... Foundation National Organization for Rare Disorders (NORD) National Tay-Sachs and Allied Diseases Association See all related ... Foundation National Organization for Rare Disorders (NORD) National Tay-Sachs and Allied Diseases Association See all related ...

  14. Canavan Disease

    Science.gov (United States)

    ... Foundation, Inc. Canavan Research Foundation Genetic Alliance National Tay-Sachs and Allied Diseases Association See all related ... Foundation, Inc. Canavan Research Foundation Genetic Alliance National Tay-Sachs and Allied Diseases Association See all related ...

  15. Digestive Diseases

    Science.gov (United States)

    ... Celiac Disease Bowel Control Problems (Fecal Incontinence) Gas Lactose Intolerance Diarrhea Diverticulosis & Diverticulitis Acid Reflux (GER & GERD) More Digestive Disease Topics Children and Teens Acid Reflux (GER & GERD) in Infants Acid Reflux (GER & GERD) in Children & Teens Chronic ...

  16. Gaucher Disease

    Science.gov (United States)

    Gaucher disease is a rare, inherited disorder. It is a type of lipid metabolism disorder. If you have ... affected. It usually starts in childhood or adolescence. Gaucher disease has no cure. Treatment options for types 1 ...

  17. Liver disease

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000205.htm Liver disease To use the sharing features on this page, please enable JavaScript. The term "liver disease" applies to many conditions that stop the ...

  18. Wilson Disease

    Science.gov (United States)

    ... in copper, such as –shellfish –liver –mushrooms –nuts –chocolate • A person cannot prevent Wilson disease; however, people with a family history of Wilson disease, especially those with an affected ...

  19. Chagas Disease

    Science.gov (United States)

    Chagas disease is caused by a parasite. It is common in Latin America but not in the United ... There are no vaccines or medicines to prevent Chagas disease. If you travel to areas where it occurs, ...

  20. Legionnaires' Disease

    Science.gov (United States)

    ... Disease Sources Investigation Protocol Outbreak Response What is Legionella? Exposure and Transmission Disease Symptoms Incidence and Risk ... form of pneumonia. More than 43 species of Legionella have been identified and more than 20 linked ...

  1. Heart Disease

    Science.gov (United States)

    ... daily aspirin to prevent heart attack? Does taking birth control pills increase my risk for heart disease? Does using ... tells you to. Return to top Does taking birth control pills increase my risk for heart disease? Taking birth ...

  2. Liver Disease

    Science.gov (United States)

    ... stay still. Liver disease has many causes. Infection Parasites and viruses can infect the liver, causing inflammation ... beyond. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/ ...

  3. Kidney Diseases

    Science.gov (United States)

    ... until you go to the bathroom. Most kidney diseases attack the nephrons. This damage may leave kidneys ... medicines. You have a higher risk of kidney disease if you have diabetes, high blood pressure, or ...

  4. Eye Diseases

    Science.gov (United States)

    ... the back of the eye Macular degeneration - a disease that destroys sharp, central vision Diabetic eye problems ... defense is to have regular checkups, because eye diseases do not always have symptoms. Early detection and ...

  5. Parasitic Diseases

    Science.gov (United States)

    ... water, a bug bite, or sexual contact. Some parasitic diseases are easily treated and some are not. Parasites ... can be seen with the naked eye. Some parasitic diseases occur in the United States. Contaminated water supplies ...

  6. Reimplante mediato de dentes tratados ou não com solução de hipoclorito de sódio a 1% - estudo histomorfométrico em ratos Effects of sodium hypochlorite on periodontal healing after tooth replantation - histomorphometric study in rats

    Directory of Open Access Journals (Sweden)

    Cláudia Misue KANNO

    2000-06-01

    Full Text Available Foi avaliada a influência do hipoclorito de sódio a 1% no reparo do periodonto de incisivos reimplantados tardiamente em ratos. Os dentes foram mantidos em meio ambiente durante 30 minutos e a seguir imersos em hipoclorito de sódio a 1%, por 25 minutos. Os animais foram sacrificados aos 10, 30 ou 60 dias. Os cortes histológicos foram obtidos no sentido transversal dos terços cervical, médio e apical e delineados com um aumento de 52 vezes. Os eventos observados sobre a superfície radicular foram medidos quanto a sua extensão através de um sistema analisador de imagens (Mini-Mop, Carl Zeiss. Aos 10 dias, observou-se a predominância de tecido conjuntivo fibroso no grupo tratado. Aos 30 e 60 dias observou-se o aumento da anquilose e reabsorção por substituição, assim como neoformação limitada de ligamento periodontal. No grupo controle, aos 30 e 60 dias, foram observadas áreas de reabsorções mais extensas e profundas, quando comparadas ao grupo tratado. Os resultados possibilitaram as seguintes conclusões quando comparado o grupo tratado com o controle: a leva à formação de tecido conjuntivo semelhante a uma cápsula fibrosa no período inicial do reparo; b possibilita uma limitada neoformação de ligamento periodontal; c ocasiona uma superfície de anquilose mais extensa; d não impede a reabsorção por substituição.The aim of the present study was to examine the influence of 1% sodium hypochlorite on periodontal healing after tooth replantation. Rats incisors were extracted, maintained in the environment during 30 minutes, then immersed in 1% sodium hypochlorite for 30 minutes. In the control group, the teeth were maintained in distilled water. The animals were sacrificed after 10, 30 and 60 days. Transversal slices of the teeth were obtained and histologically processed through the hematoxylin and eosin technique. Slices from the cervical, middle and apical thirds of each tooth were selected for the analysis. The

  7. 指侧方岛状皮瓣和微型静脉皮瓣的局部解剖及在皮肤缺损型断指再植中的应用%Anatomy and Clinical Application of Finger Side Quadrate Island Flap and Miniature Vein Skin Flap in Replantation of Severed finger with Skin Defect

    Institute of Scientific and Technical Information of China (English)

    胡洪涌; 刘国龙; 王威; 黄桂桃; 赵小伟

    2011-01-01

    目的 研究指侧方岛状皮瓣和微型静脉皮瓣的局部解剖及在皮肤缺损型断指再植修复中的临床应用.方法 分别利用上肢血管铸形标本、前臂取皮手术标本、新鲜废弃手部标本及活体手部体表测量标本等进行应用解剖研究,并在此基础上,按掌侧、背侧及环状缺损3种类型选取皮肤缺损型断指病例18例19指,分别设计指侧方岛状皮瓣、前臂微型游离静脉皮瓣及前2种皮瓣之联合皮瓣3种术式进行再植修复.结果 19指及皮瓣均成活;患指长度无明显短缩,外观良好,移植皮瓣质地良好;患指功能TAM评分:优7指,良9指,差3指,优良率为84.21%.结论 指侧方岛状皮瓣和微型静脉皮瓣可灵活应用于各种类型的皮肤缺损型断指的再植修复.%Objective To research the regional anatomy and the clinical application of finger side quadrate island flap and miniature vein skin flap in replantation of severed finger with skin defect. Methods The applied anatomy was studied by using upper limb vessel casting specimens,forearm skin surgical specimens, fresh abandoned hand specimens and in vivo surface hand measurement specimens. According to different defect location (palmar defect, dorsal defect and ring defect), 19 fingers of 18 patients with finger amputation were selected and repaired using finger side quadrate island flap, forearm miniature free vein skin flap and the combined flaps for replanlation of amputated fingers,respectively. Results Skin flaps survived in all cases and the length of repaired fingers did not shortened. The repaired fingers had good appearance and high-quailty skin flaps. TAM showed excellent in 7 fingers,good in 9 and bad in 3. The excellent and good rate was 84.21%. Conclusion Finger side quadrate island flap and miniature vein skin flap can be extensively used in different types of replanlation of amputated finger with skin defect.

  8. Kawasaki Disease

    Science.gov (United States)

    ... Life7. Questions8. Resources What is Kawasaki disease? Kawasaki disease is a rare illness. It can occur in infants and children younger ... may have diarrhea, vomiting, and stomach pain. Kawasaki disease might make your child irritable. The illness can last for a few weeks. What causes ...

  9. Lyme Disease.

    Science.gov (United States)

    Taylor, George C.

    1991-01-01

    This overview of the public health significance of Lyme disease includes the microbiological specifics of the infectious spirochete, the entomology and ecology of the ticks which are the primary disease carrier, the clinical aspects and treatment stages, the known epidemiological patterns, and strategies for disease control and for expanded public…

  10. [Gaucher Disease].

    Science.gov (United States)

    Okuyama, Torayuki

    2015-09-01

    Gaucher disease is an autosomal recessive disorder caused by congenital deficiency of lysosomal glucocerebrosidase. Gaucher disease is classified into three types. In addition to enzyme replacement therapy, substrate reduction therapy, chemical chaperon therapy, and hematopoietic stem cell transplantation therapy are considered for the effective treatment of Gaucher disease.

  11. Menetrier's Disease

    Science.gov (United States)

    ... producing cells in the stomach, which decreases stomach acid. Ménétrier’s disease is also called Ménétrier disease or hypoproteinemic hypertrophic ... Alternate Versions PDF Version (102 KB) Additional Links Peptic Ulcer Disease Upper GI Endoscopy This content is provided as ...

  12. Glomerular Diseases

    Science.gov (United States)

    ... Disease Mineral & Bone Disorder Diabetes Inspidus Glomerular Diseases Goodpasture Syndrome Henoch-Schönlein Purpura IgA Nephropathy Kidney Disease in ... effective as cyclophosphamide and has milder side effects. Goodpasture's Syndrome involves an autoantibody that specifically targets the kidneys ...

  13. Prion病与睡眠障碍%Prion diseases and sleep disorders

    Institute of Scientific and Technical Information of China (English)

    詹淑琴; 郭彩凤; 王玉平; 贾建平

    2013-01-01

    Prion diseases (PrD) are a group of encephalopathies with neurodegenerative changes caused by prion protein (PrP) whose characteristic datum is transmissibility.In most cases they occur in a sporadic form although a group of them are familial associated with mutations in PrP gene.Phenotypic variability of fatal familial insomnia (FFI) versus familial Creutzfeldt-Jakob disease178 (fCJD178) seems to determine the different methionine-valine polymorphism at codon 129 of the PrP gene.Sleep disorders is one of the important clinical features for the diagnosis and definition of PrD.FFI,a hereditary disorder characterized by loss of physiological sleep with oneiric stupor,autonomic and motor hyperactivity.The polysomnography (PSG) shows disappearance of the physiological pattern of non-rapid eye movement (NREM) and rapid eye movement (REM) sleep,as well as sleep spindles and K-complexes were absent.The hypothesis of the origin of these disorders is thalamic neuronal loss,especially in the anterior and dorsomedial nuclei,described in the neuropathology of these patients; besides,PET reveals hypofunction of thalamic nuclei,centres responsible for controlling wake-sleep.In CJD the wake-sleep disorders is not considered characteristic; nonetheless,frequent alterations have been found in the electroencephalographic registers of sleep.Besides thalamic neurodegeneration,there could be common etiopathogenic mechanisms in PrD in relation to the biological function of PrP.%Prion病是由传染性朊蛋白侵袭中枢神经系统引起的致死性神经变性脑病,睡眠障碍在Prion病中十分常见,也是其诊断特征之一.其中致死性家族性失眠症表现为严重的生理睡眠缺失及特殊梦幻状态、自主神经功能失调和过度运动;多导睡眠图早期睡眠纺锤波和K复合波消失,无法产生快速眼动和非快速眼动睡眠生理循环.除PET扫描呈现丘脑低代谢,神经病理学观察可见丘脑神经元大量缺失,尤其是丘脑

  14. Reforesting unused surface mined lands by replanting with native trees

    Science.gov (United States)

    Patrick N. Angel; James A. Burger; Carl E. Zipper; Scott Eggerud

    2012-01-01

    More than 600,000 ha (1.5 million ac) of mostly forested land in the Appalachian region were surface mined for coal under the Surface Mining Control and Reclamation Act. Today, these lands are largely unmanaged and covered with persistent herbaceous species, such as fescue (Festuca spp.) and sericea lespedeza (Lespedeza cuneata [Dum. Cours.] G. Don,) and a mix of...

  15. [Face replantation using labial artery for revascularization. Case report].

    Science.gov (United States)

    de la Parra-Márquez, Miguel; Mondragón-González, Sergio; López-Palazuelos, Jaime; Naal-Mendoza, Norberto; Rangel-Flores, Jesús María

    2013-01-01

    antecedentes: la restauración cosmética y funcional de la cara luego de un traumatismo complejo es todo un reto para el cirujano plástico. En el ámbito internacional se han reportado pocos casos de reimplante facial. Objetivo: reportar el caso del primer reimplante parcial de cara con la utilización de la arteria labial como aporte vascular. Caso clínico: paciente masculino de siete años de edad. Ingresó al servicio de Cirugía Plástica en el mes de junio de 2011 por lesiones secundarias en la cara ocasionadas por la mordedura de un perro. A la exploración física se encontró avulsión de 75% del labio superior, 33% del labio inferior, incluida la comisura oral, y 75% de la mejilla izquierda. Los músculos avulsionados incluían: el orbicular de los labios, depresor del ángulo oral y depresor del labio inferior. El tiempo total de isquemia fue de ocho horas. La anastomosis término-terminal de la arteria coronaria labial se efectuó con nylon 11-0, posteriormente se escogió la vena con mejor retorno y la anastomosis se realizó con nylon 11-0. Se hizo miorrafía de los músculos mencionados con vicril 4-0, la sutura de la mucosa oral se realizó con vicril 5-0, y de la piel con nylon 5-0. Seis meses después de la cirugía, el resultado cosmético y funcional se consideró excelente, con restablecimiento total de la continencia labial y articulación completa de las palabras. Conclusiones: las amputaciones de cualquier componente facial deben ser inicialmente tratadas con reimplante. La arteria coronaria labial es una buena opción para revascularización, incluso en 25% del total de la cara (labios y mejilla).

  16. La replantation annuelle de la culture de bananier plantain : une ...

    African Journals Online (AJOL)

    SARAH

    31 août 2015 ... populations. L'objectif de cette étude est de réduire la pression parasitaire des principales espèces .... après plantation (fin de la phase de croissance), 236 jours après ..... coordination du projet et le Centre National de.

  17. Control strategies for grapevine phytoplasma diseases: factors influencing the profitability of replacing symptomatic plants

    Directory of Open Access Journals (Sweden)

    Francesco PAVAN

    2012-05-01

    Full Text Available The course of ‘flavescence dorée’ (FD and ‘bois noir’ (BN diseases can result in either recovery or death of affected grapevines. When farmers observe symptomatic grapevines, they must choose whether to replace or maintain the plants. To establish whether there is an advantage in replacing symptomatic grapevines, data were collected on the costs of replacing them (removing the diseased plants and planting new grapevines, with resultant yield loss during the rearing period and growing them on (yield losses in symptomatic grapevines over the following years. To calculate the cost of maintaining FD-infected plants, the possibility was also considered that symptomatic grapevines may be sources of phytoplasmas for the vector Scaphoideus titanus Ball. The symptomatic course of BN was observed in ‘Chardonnay’, and of FD in ‘Chardonnay’, ‘Merlot’ and ‘Perera’ grape cultivars. The costs of replacement decreased with the increase in the productive lifetime of the vineyards. The cost of maintenance was greatly influenced by the course of the diseases, and in the case of FD, also by the risk of new infections due to the fact that S. titanus acquires phytoplasmas from infected grapevines. The replacement of plants affected by BN is not profitable when recovery is the most frequent course of the disease, particularly when it is considered that replantings can, in turn, become infected. The replacement of plants affected by FD is not profitable for cultivars with a recovery near to 100% (‘Merlot’, whereas it is necessary for cultivars where the course of the disease is frequently lethal (‘Perera’. For cultivars with intermediate sensitivity, the decision varies in relation to agronomic/economic factors and to the risk of new infections (‘Chardonnay’. For FD, both replacement and maintenance strategies need to be associated with S. titanus control inside and outside the vineyards. In the case of maintenance the infected

  18. Morgellons Disease

    OpenAIRE

    Ohn, Jungyoon; Park, Seon Yong; Moon, Jungyoon; Choe, Yun Seon; Kim, Kyu Han

    2017-01-01

    Morgellons disease is a rare disease with unknown etiology. Herein, we report the first case of Morgellons disease in Korea. A 30-year-old woman presented with a 2-month history of pruritic erythematous patches and erosions on the arms, hands, and chin. She insisted that she had fiber-like materials under her skin, which she had observed through a magnifying device. We performed skin biopsy, and observed a fiber extruding from the dermal side of the specimen. Histopathological examination sho...

  19. Celiac Disease

    Directory of Open Access Journals (Sweden)

    Hero Brokalaki

    2008-07-01

    Full Text Available Celiac disease is a small intestine disease caused by the immunological response to gluten, a component of wheat, rye and barley. The worldwide prevalence of celiac disease ranges between 0.2% and 2.2 %. The clinical features of celiac disease includes diarrhea, steatorrhea, flatulence, abdominal pain and weight loss. The asymptomatic type of celiac disease is characterized by soft or normally shaped stool, weakness, lassitude and moderate weight loss. In children, celiac disease usually arises between the first and the third year of age, with diarrhea, flatulence and low weight. The malabsorption in small intestine causes many extaintestinal manifestations, such us anemia, bone abnormalities, hemorrhage and neuropathy. Celiac disease is diagnosed by histological examination of tissue samples taken by duodenum due gastroscopy and by the detection of certain antibodies in blood (anti-GL-IgG, anti-GL-IgA, ΕΜΑ-IgA και anti-tTg-IgA. The only therapeutic approach to celiac disease is a gluten-free diet and, if it is necessary, the administration of iron, folic acid, calcium and vitamins (K, B12. The prognosis of celiac disease is excellent, if there is an early diagnosis and the patient keeps for life a gluten free diet.

  20. Celiac disease

    Directory of Open Access Journals (Sweden)

    Holtmeier Wolfgang

    2006-03-01

    Full Text Available Abstract Celiac disease is a chronic intestinal disease caused by intolerance to gluten. It is characterized by immune-mediated enteropathy, associated with maldigestion and malabsorption of most nutrients and vitamins. In predisposed individuals, the ingestion of gluten-containing food such as wheat and rye induces a flat jejunal mucosa with infiltration of lymphocytes. The main symptoms are: stomach pain, gas, and bloating, diarrhea, weight loss, anemia, edema, bone or joint pain. Prevalence for clinically overt celiac disease varies from 1:270 in Finland to 1:5000 in North America. Since celiac disease can be asymptomatic, most subjects are not diagnosed or they can present with atypical symptoms. Furthermore, severe inflammation of the small bowel can be present without any gastrointestinal symptoms. The diagnosis should be made early since celiac disease causes growth retardation in untreated children and atypical symptoms like infertility or neurological symptoms. Diagnosis requires endoscopy with jejunal biopsy. In addition, tissue-transglutaminase antibodies are important to confirm the diagnosis since there are other diseases which can mimic celiac disease. The exact cause of celiac disease is unknown but is thought to be primarily immune mediated (tissue-transglutaminase autoantigen; often the disease is inherited. Management consists in life long withdrawal of dietary gluten, which leads to significant clinical and histological improvement. However, complete normalization of histology can take years.

  1. Leigh's Disease

    Science.gov (United States)

    ... Related Dementias Bioengineering Epilepsy Health Disparities Neural Interfaces Parkinson's Disease Spinal Cord Injury Stem Cells Traumatic Brain Injury Trans-Agency Activities Interagency Research ...

  2. Celiac disease

    Directory of Open Access Journals (Sweden)

    Radlović Nedeljko

    2013-01-01

    Full Text Available Celiac disease is a multysystemic autoimmune disease induced by gluten in wheat, barley and rye. It is characterized by polygenic predisposition, high prevalence (1%, widely heterogeneous expression and frequent association with other autoimmune diseases, selective deficit of IgA and Down, Turner and Williams syndrome. The basis of the disease and the key finding in its diagnostics is symptomatic or asymptomatic inflammation of the small intestinal mucosa which resolves by gluten-free diet. Therefore, the basis of the treatment involves elimination diet, so that the disorder, if timely recognized and adequately treated, also characterizes excellent prognosis.

  3. Is "Parkinson's disease" one disease?

    OpenAIRE

    Calne, D B

    1989-01-01

    Consideration is given to how and why categories of ill health are divided into diseases. Aetiology is a fundamental criterion for the delineation of individual diseases. The same clinical and pathological picture may have many different causes; for example meningococcal meningitis and pneumococcal meningitis are distinct diseases that may display the same symptoms and signs. On the other hand, a single aetiology may lead to quite separate clinical and pathological phenomena; for example, neu...

  4. Endocrine Diseases

    Science.gov (United States)

    ... high or too low, you may have an endocrine disease or disorder. Endocrine diseases and disorders also occur if your body does not respond to hormones the way it is supposed to. Featured Topics Adrenal Insufficiency ... Topics Research Discoveries & News Children with Cushing ...

  5. Batten Disease

    Science.gov (United States)

    ... children with Batten disease who were treated with vitamins C and E and with diets low in vitamin A. However, these treatments did not prevent the ... Complications of AIDS Information Page Neurological Complications of Lyme Disease ... Page Neuromyelitis Optica Information Page Neuronal Migration ...

  6. Myocardial disease

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    970309 Myocardial injury of Keshan disease andapoptosis. ZHONG Xuekuan(钟学宽), et al. KeshanDis Instit, Harbin Med Univ, Harbin, 150086. Chin JEndemiol 1997, 16(2): 81-82. Objective: To discuss the relationship between my-ocardial injury Of Keshan disease and apoptosis. Meth-

  7. Wilson Disease

    Science.gov (United States)

    ... individuals with WD is liver disease, appearing in late childhood or early adolescence as acute hepatitis, liver failure, or progressive chronic ... individuals with WD is liver disease, appearing in late childhood or early adolescence as acute hepatitis, liver failure, or progressive chronic ...

  8. Kidney Disease

    Science.gov (United States)

    ... version of this page please turn Javascript on. Kidney Disease What is Kidney Disease? What the Kidneys Do Click for more information You have two ... damaged, wastes can build up in the body. Kidney Function and Aging Kidney function may be reduced ...

  9. Hartnup disease

    Directory of Open Access Journals (Sweden)

    Jerajani Hemangi

    1994-01-01

    Full Text Available A rare case of Hartnup disease is presented - the patient being an 11 year old school girl suffering from a typically pellagroid rash in the absence of any other signs of malnutrition. No accompanying neurological or psychiatric features are seen, but electro-encephalography revealed abnormal baseline activity. Investigations and management are detailed and the literature on Hartnup disease reviewed.

  10. Disease Lab

    OpenAIRE

    Powell, Jim; Lewis, Matt

    2016-01-01

    Students use transparencies and dry erase markers to simulate the spread of a zombie virus among a fixed population. Students are then challenged to create their own "disease" and develop an ODE model for the resulting data. From this exercise students gain greater understanding of population and SIR models, disease dynamics, parameter estimation and compartment modeling.

  11. Alzheimer's Disease

    Science.gov (United States)

    ... to note that Alzheimer's disease is not a normal part of aging. What Is Alzheimer's Disease? Video length: 2 min 29 sec Click to watch this video The course of Alzheimer’s disease—which symptoms appear and how quickly changes occur—varies from person to person. The time ...

  12. Facioscapulohumeral disease

    NARCIS (Netherlands)

    Padberg, George Waltherus Adrianus Maria

    1982-01-01

    The purpose of this study is to discuss several aspects of facioscapulohumeral disease, also called "autosomal dominant facioscapulohumeral muscular dystrophy" or "Landouzy-Dejerine type of muscular dystrophy" or "Landouzy-Dejerine' s disease" . We consider this disorder well defined and

  13. Whipple Disease

    Science.gov (United States)

    ... more common conditions with similar symptoms, including • inflammatory rheumatic disease— characterized by inflammation and loss of function in ... way to prevent Whipple disease. Eating, Diet, and Nutrition A person with Whipple disease and malabsorption may need • a diet high in ...

  14. Krabbe Disease

    Science.gov (United States)

    ... books/NBK1238/. Accessed Feb. 28, 2014. Krabbe disease. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/krabbe-disease. Accessed Feb, 28. 2014. Ropper AH, et al. Adams & Victor's Principles of Neurology. 9th ed. New York, N.Y.: ...

  15. Periodontal Disease and Systemic Health

    Science.gov (United States)

    ... Gum Disease and Other Diseases Gum Disease and Diabetes Gum Disease and Heart Disease Gum Disease and Other Systemic ... Gum Disease and Other Diseases Gum Disease and Diabetes Gum Disease and Heart Disease Gum Disease and Other Systemic ...

  16. Vascular Disease Foundation

    Science.gov (United States)

    ... Contact Us Vascular Disease What is Vascular Disease? Education and Awareness Vascular Diseases Abdominal Aortic Aneurysm Aortic Dissection Arteriovenous Malformation Atherosclerosis Buerger's Disease Carotid Artery Disease ...

  17. What Is Vascular Disease?

    Science.gov (United States)

    ... Contact Us Vascular Disease What is Vascular Disease? Education and Awareness Vascular Diseases Abdominal Aortic Aneurysm Aortic Dissection Arteriovenous Malformation Atherosclerosis Buerger's Disease Carotid Artery Disease ...

  18. Celiac Disease

    Directory of Open Access Journals (Sweden)

    Manoochehr Karjoo

    2014-08-01

    Full Text Available Celiac disease also known as gluten-sensitive enteropathy is characterized by intestinal mucosal damage and malabsorption from dietary intake of wheat, rye or barley. Symptoms may appear with introduction of cereal in the first 3 years of life. A second peak in symptoms occurs in adults during the third or forth decade and even as late as eight decade of life. The prevalence of this disease is approximately 1 in 250 adults. The disease is more prevalent in Ireland as high as 1 in 120 adults. The disorder occurs in Arab, Hispanics, Israeli Jews, Iranian and European but is rare in Chinese and African American. To have celiac disease the patient should have the celiac disease genetic markers as HLA DQ 2 and HLA DQ 8. Patient with celiac disease may have 95 per cent for DQ 2 and the rest is by DQ 8. Someone may have the genetic marker and never develops the disease. In general 50 percent with markers may develop celiac disease. To develop the disease the gene needs to become activated. This may happen with a viral or bacterial infection, a surgery, delivery, accident, or psychological stress. After activation of gene cause the tight junction to opens with the release of Zonulin This results in passage of gluten through the tight junction and formation of multiple antibodies and autoimmune disease. This also allows entrance of other proteins and development of multiple food allergies. As a result is shortening, flattening of intestinal villi resulting in food, vitamins and minerals malabsorption.

  19. Pompe's disease.

    Science.gov (United States)

    van der Ploeg, Ans T; Reuser, Arnold J J

    2008-10-11

    Pompe's disease, glycogen-storage disease type II, and acid maltase deficiency are alternative names for the same metabolic disorder. It is a pan-ethnic autosomal recessive trait characterised by acid alpha-glucosidase deficiency leading to lysosomal glycogen storage. Pompe's disease is also regarded as a muscular disorder, but the generalised storage of glycogen causes more than mobility and respiratory problems. The clinical spectrum is continuous and broad. First symptoms can present in infants, children, and adults. Cardiac hypertrophy is a key feature of classic infantile Pompe's disease. For a long time, there was no means to stop disease progression, but the approval of enzyme replacement therapy has substantially changed the prospects for patients. With this new development, the disease is now among the small but increasing number of lysosomal storage disorders, for which treatment has become a reality. This review is meant to raise general awareness, to present and discuss the latest insights in disease pathophysiology, and to draw attention to new developments about diagnosis and care. We also discuss the developments that led to the approval of enzyme replacement therapy with recombinant human alpha-glucosidase from Chinese hamster ovary cells (alglucosidase alfa) by the US Food and Drug Administration and European Medicines Agency in 2006, and review clinical practice.

  20. Refractory disease in autoimmune diseases

    NARCIS (Netherlands)

    Vasconcelos, Carlos; Kallenberg, Cees; Shoenfeld, Yehuda

    2011-01-01

    Refractory disease (RD) definition has different meanings but it is dynamic, according to knowledge and the availability of new drugs. It should be differentiated from severe disease and damage definitions and it must take into account duration of adequate therapy and compliance of the patient. It c

  1. Kummell disease.

    Science.gov (United States)

    Nickell, Larry T; Schucany, William G; Opatowsky, Michael J

    2013-07-01

    Kummell disease, or avascular necrosis of a vertebral body, presents as vertebral osteonecrosis typically affecting a thoracic vertebra with compression deformity, intravertebral vacuum cleft, and exaggerated kyphosis weeks to months after a minor traumatic injury. This rare disease is increasing in prevalence secondary to an aging population and the associated rise in osteoporosis. Treatment with vertebroplasty or surgical decompression and fusion is often required. We present a classic case of Kummell disease to illustrate the salient features of the condition, with associated imaging findings on computed tomography and magnetic resonance imaging.

  2. Crohn's disease.

    LENUS (Irish Health Repository)

    Shanahan, Fergus

    2012-02-03

    Crohn\\'s disease is a disorder mediated by T lymphocytes which arises in genetically susceptible individuals as a result of a breakdown in the regulatory constraints on mucosal immune responses to enteric bacteria. Regulation of immune reactivity to enteric antigens has improved understanding of the pathophysiological mechanisms of Crohn\\'s disease, and has expanded therapeutic options for patients with this disorder. Disease heterogeneity is probable, with various underlying defects associated with a similar pathophysiological outcome. Although most conventional drug treatments are directed at modification of host response, therapeutic manipulation of the enteric flora is becoming a realistic option.

  3. Fahr's Disease

    Directory of Open Access Journals (Sweden)

    Tezcan Caliskan

    2013-06-01

    Full Text Available Fahr's disease refers to sporadic or familial idiopathic basal ganglia, cerebral and cerebellar calcification. Patients may remain symptom-free but approximately two-thirds of the patients are symptomatic. Typical presentation starts in the 4th to 5th decades of life. Patients present with pyramidal, extrapyramidal, cerebellar, psychiatric and cognitive manifestations. Various diagnostic studies can be used to detect Fahr's disease and associated abnormalities. There is no specific treatment other than symptomatic support. In this review, clinical features and different types of presentations of Fahr's disease are discussed under the light of current literature. [J Contemp Med 2013; 3(2.000: 133-135

  4. [Fabry disease].

    Science.gov (United States)

    Boggio, Paula; Luna, Paula Carolina; Abad, María Eugenia; Larralde, Margarita

    2009-01-01

    Fabry disease is an uncommon, X-linked lysosomal storage disorder, caused by partial or complete deficiency of the enzyme a-galactosidase A. The defect leads to accumulation of uncleaved globotriaosylceramide on the vascular endothelium and visceral tissues, being the skin, heart, kidneys and central nervous system the most affected organs. We performed review of the literature related to the disease and emphasized that early recognition of angiokeratomas and hypohidrosis are key diagnostic signs of this serious disease. We also addressed the need of multidisciplinary assessment of these patients.

  5. Morgellons Disease.

    Science.gov (United States)

    Ohn, Jungyoon; Park, Seon Yong; Moon, Jungyoon; Choe, Yun Seon; Kim, Kyu Han

    2017-04-01

    Morgellons disease is a rare disease with unknown etiology. Herein, we report the first case of Morgellons disease in Korea. A 30-year-old woman presented with a 2-month history of pruritic erythematous patches and erosions on the arms, hands, and chin. She insisted that she had fiber-like materials under her skin, which she had observed through a magnifying device. We performed skin biopsy, and observed a fiber extruding from the dermal side of the specimen. Histopathological examination showed only mild lymphocytic infiltration, and failed to reveal evidence of any microorganism. The polymerase chain reaction for Borrelia burgdorferi was negative in her serum.

  6. Stargardt Disease

    Science.gov (United States)

    ... Resources Low Vision Specialists Retinal Physicians My Retina Tracker Registry Genetic Testing Clinical Trials Join the Fight ... of lipofuscin, a fatty byproduct of normal cell activity. In Stargardt disease, lipofuscin accumulates abnormally. The Foundation ...

  7. Pick disease

    Science.gov (United States)

    ... in behavior Failure to show emotional warmth, concern, empathy, sympathy Inappropriate mood Not caring about events or ... and steadily becomes worse. The person becomes totally disabled early in the course of the disease. Pick ...

  8. Vaginal Diseases

    Science.gov (United States)

    Vaginal problems are some of the most common reasons women go to the doctor. They may have ... that affect the vagina include sexually transmitted diseases, vaginal cancer, and vulvar cancer. Treatment of vaginal problems ...

  9. Legionnaires' Disease

    Science.gov (United States)

    Legionnaires' disease is a type of pneumonia caused by bacteria. You usually get it by breathing in mist from water that contains the bacteria. The mist may come from hot tubs, showers, or air-conditioning units for ...

  10. Infectious Diseases

    Science.gov (United States)

    ... people worldwide than any other single cause. Infectious diseases are caused by germs. Germs are tiny living things that are found everywhere - in air, soil and water. You can get infected by touching, eating, drinking ...

  11. Parkinson's Disease

    Science.gov (United States)

    ... sleep behavior disorder, which involves acting out your dreams. Medications may help your sleep problems. Bladder problems. ... will diagnose Parkinson's disease based on your medical history, a review of your signs and symptoms, and ...

  12. Gaucher Disease

    Science.gov (United States)

    ... Translational Research Research at NINDS Focus on Research Alzheimer's & Related Dementias Bioengineering Epilepsy Health Disparities Neural Interfaces Parkinson's Disease Spinal Cord Injury Stem Cells Traumatic Brain Injury Trans-Agency Activities Interagency Research ...

  13. Alexander Disease

    Science.gov (United States)

    ... Translational Research Research at NINDS Focus on Research Alzheimer's & Related Dementias Bioengineering Epilepsy Health Disparities Neural Interfaces Parkinson's Disease Spinal Cord Injury Stem Cells Traumatic Brain Injury Trans-Agency Activities Interagency Research ...

  14. Menkes Disease

    Science.gov (United States)

    ... Translational Research Research at NINDS Focus on Research Alzheimer's & Related Dementias Bioengineering Epilepsy Health Disparities Neural Interfaces Parkinson's Disease Spinal Cord Injury Stem Cells Traumatic Brain Injury Trans-Agency Activities Interagency Research ...

  15. Tickborne Diseases

    Science.gov (United States)

    ... of Award Clinical Terms of Award Restriction for China Clinical Terms Guidance Compliance Sample Letter Inclusion Codes ... Division of AIDS Division of Allergy, Immunology, and Transplantation Division of Microbiology and Infectious Diseases Division of ...

  16. Prion Diseases

    Science.gov (United States)

    ... of Award Clinical Terms of Award Restriction for China Clinical Terms Guidance Compliance Sample Letter Inclusion Codes ... Division of AIDS Division of Allergy, Immunology, and Transplantation Division of Microbiology and Infectious Diseases Division of ...

  17. [Prion diseases].

    Science.gov (United States)

    Zarranz, J J

    2006-10-01

    Prion diseases are one of the paradigms of modern neurological nosology founded on molecular grounds. Their incidence is low, however the public health challenges derived from their transmissibility, especially due to the appearance of a variant of Creutzfeldt-Jakob disease (vCJD) confers them a preferential place among health care authority concerns. The evolution of data from the European surveillance systems suggests a generalized underdiagnosis of prion diseases and casts doubts about their ability to detect a possible second wave of atypical vCJD, especially if their clinical-pathological characteristics change. Recent data also challenge the feasibility of a subclassification of prion diseases according to their genetic-molecular features

  18. Celiac Disease

    Science.gov (United States)

    ... gluten and to certain other proteins in the intestinal lining — a sign that the person could have celiac disease — then the doctor may order a biopsy of the small intestine to confirm the diagnosis. In the case of ...

  19. Autoinflammatory Diseases

    Science.gov (United States)

    ... disease. Colchicine – a medication also approved to treat gout (a form of arthritis) – has been used successfully as a treatment for FMF. Colchicine reduces inflammation throughout the body. ...

  20. Behcet's disease.

    Science.gov (United States)

    Nair, Jagdish R; Moots, Robert J

    2017-02-01

    Behçet's disease (BD) is a chronic relapsing and remitting vasculitis of unknown aetiology. It has the capacity to affect almost all organ systems because of its potential to involve both arteries and veins of all sizes, resulting in significant organ-threatening morbidity and mortality. Traditionally known as the 'silk road' disease, it has a worldwide occurrence. The aetiopathological mechanisms of disease development in BD remain poorly understood, but genome wide studies show human leukocyte antigen and non-human leukocyte antigen associations. Environmental influences and genetic factors may have a role in the aetiopathogenetic mechanisms that lead to development of the disease, indicating the autoimmune and auto-inflammatory nature of BD. The evidence base for treatment is limited but new knowledge is emerging and current treatment options range from symptomatic treatment, through to non-biological and biological immunosuppressive drugs, to cover the spectrum of clinical manifestations.

  1. Parkinson disease

    Science.gov (United States)

    ... control movement. Surgery to destroy brain tissue that causes Parkinson symptoms. Stem cell transplant and other procedures are ... in brain function and early death. Possible Complications Parkinson disease may cause problems such as: Difficulty performing daily activities Difficulty ...

  2. Heart Disease

    Science.gov (United States)

    ... Atherosclerosis is also the most common cause of cardiovascular disease. It can be caused by correctable problems, such as an unhealthy diet, lack of exercise, being overweight and smoking. Causes of heart arrhythmia ...

  3. Lyme Disease

    Science.gov (United States)

    ... can also spread to the nervous system, causing facial paralysis ( Bell_s_palsy ), or meningitis. The last stage of ... symptoms, joint pain or a swollen joint, or facial paralysis. Can I Prevent Lyme Disease? There's no surefire ...

  4. Endocrine Diseases

    Science.gov (United States)

    Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They ... levels. In the United States, the most common endocrine disease is diabetes. There are many others. They ...

  5. Hashimoto's Disease

    Science.gov (United States)

    ... use a combination of x rays and computer technology to create images. For a CT scan, a ... than men. Although the disease often occurs in adolescent or young women, it more commonly appears between ...

  6. Gum Disease

    Science.gov (United States)

    ... away from the teeth. This is known as periodontitis (pronounced: pair-ee-oh-don-TY-tus), a more advanced form of gum disease. With periodontitis, gums become weakened and form pockets around the ...

  7. Planning Diseases.

    Science.gov (United States)

    Gabel, Medard

    1984-01-01

    To solve societal problems, both local and global, a global approach is needed. Serious diseases that are crippling present-day problem solving and planning are discussed, and the characteristics of a healthy, effective planning approach are described. (RM)

  8. [Lyme disease].

    Science.gov (United States)

    Portillo, Aránzazu; Santibáñez, Sonia; Oteo, José A

    2014-02-01

    Lyme disease (LD) is a worldwide-distributed multisystemic process caused by Borrelia burgdorferi sensu lato (s.l.) and transmitted by hard ticks. In fact, it is the most common tick-borne infectious disease in the northern hemisphere. In Spain it is transmitted by Ixodes ricinus ticks and Borrelia garinii is the genoespecies of B. burgdorferi s.l. mostly involved in our area. LD is known as "the last great imitator" due to the broad clinical spectrum that may cause. Except in the case of erythema migrans (pathognomonic feature of the disease), the remaining clinical manifestations should be confirmed using microbiological tests. This review is intended to provide readers a current vision of the etiology, epidemiology, clinical manifestations, laboratory diagnosis and treatment of Lyme disease in our environment. Controversial aspects arising from the use of non-validated microbiological tests that are being used without scientific rigor are highlighted.

  9. Extrapyramidal disease

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    2008119 Therapeutic effect of neuropeptide PACAP27 on Parkinson′s disease in mice. WANG Gang(王刚), et al.Dept Neurol & Neurol Instit, Ruijin Hosp, Shanghai Jiaotong Univ, Med Sch, Shanghai 200025. Chin J Neurol 2007;40(12):837-841. Objective To investigate the effects of different doses of pituitary adenylate cyclase-activating polypeptide (PACAP) on the functional and morphological outcome in a mice model of Parkinson′s disease (PD) re

  10. Muscular disease

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    930186 The diagnostic value of MRI on neuro-muscular disease.CHEN Qingtang(陈清棠),etal.Dept Neurol,1st Hosp,Beijing Med Univ,100034.Chin J Neurol & Psychiat 1992;25(5):267-269.The article concentrated on the study ofskeletal muscles of four extremities in 12 casesof different kinds of neuromuscular diseases and4 volunteers with MRI.The results revealed:MRI could clearly display individual muscle,muscle groups or abnormal muscles morphologi-

  11. [Ledderhose's disease].

    Science.gov (United States)

    Bardelli, M; D'Arienzo, M; Veneziani, C

    1991-01-01

    The authors describe the clinical appearance of Ledderhose disease and emphasize the association with Dupuytren disease. They report on a series of patients treated at the 2nd Orthopedic Unit of University of Florence and describe the operating technique used. They believe that the procedure of removal of nodules must always be performed in association with careful exeresis of normal tissue, employing total aponeurectomy only in revision surgery.

  12. Bowel disease

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    2008069 The application of Montreal classification in inflammatory bowel disease. YANG Chuanhua(杨川华), et al. Renji Hosp, Shanghai Instit, Shanghai Jiaotong Univ Med Coll, Shanghai 200001. Chin J Intern Med 2008;47(1):7-10. Objective To investigate the clinical features of Crohn′s disease (CD) and ulcerative colitis (UC) according to the Montreal classification. Methods The clinical data of 110 cases of CD or UC were reviewed. The age at

  13. Extrapyramidal disease

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    2008486 Neuropsychiatric problems in patients with Parkinson’s disease. ZHOU Mingzhu(周明珠), et al. Dept Neurol, Xinhua Hosp Shanghai Jiaotong Univ, Sch Med, Shanghai 200092.Natl Med J China 2008;88(21):1442-1445. Objective To survey the prevalence and distribution of neuropsychiatric problems in patients with Parkinson’s disease (PD), and to investigate their effects on life quality and the interactions among different neuropsychiatric problems.

  14. Huntington's disease

    OpenAIRE

    Bates, G P; Dorsey, R.; Gusella, J F; Hayden, M. R.; Kay, C; Leavitt, B. R.; Nance, M; Ross, C A; Scahill, R. I.; Wetzel, R.; Wild, E. J.; Tabrizi, S.J.

    2015-01-01

    Huntington’s disease is devastating to patients and their families — with autosomal dominant inheritance, onset typically in the prime of adult life, progressive course and combination of motor, cognitive and behavioural features. The disease is caused by an expanded CAG trinucleotide repeat (of variable length) in HTT, the gene which encodes the protein huntingtin. In mutation carriers, huntingtin is produced with abnormally long polyglutamine sequences that confers toxic gains of function a...

  15. [Kawasaki's disease].

    Science.gov (United States)

    Cortes, J; Martínez, B; Montini, C; Barraza, P; Reyes, A

    1989-08-01

    We described a case of Kawasaki's disease in a chilean girl, one year and 5 months old of age, who presented the oral characteristics, cutaneous and systemic manifestation of the condition, that is not very common for the dentist but that it is necessary to know due to the heart complications and the mortality associated with the disease, and it is necessary that the dentist recognize early this condition.

  16. HIRAYAMA DISEASE

    Directory of Open Access Journals (Sweden)

    Shaik Sulaiman

    2016-05-01

    Full Text Available Hirayama’s disease, also known as Monomelic Amyotrophy (MMA, juvenile non-progressive amyotrophy, Sobue disease. It is rare and benign condition. It is a focal, lower motor neuron type of disorder, which occurs mainly in young males. Age of onset, it is first seen most commonly in people in their second and third decades. Geographically, it is seen most commonly in Asian countries like India and Japan. Cause of this disease is unknown in most cases. MRI of cervical spine in flexion is the investigation of choice, which will reveal the cardinal features of Hirayama disease. CASE REPORT 20 years old male came with the complaints of tremors of both hands more of right hand and weakness and wasting of right hand, which is slowly progressive for past 6 months. Lower limbs had no abnormality with normal deep tendon reflexes. On examination, there was wasting and weakness of hypothenar and interosseous muscles of right hand. MRI showed thinning of cord from C5 to C7 level. Proximal epidural fat and tiny flow voids with anterior migration of the posterior dural layer at C5-7 level on flexion MRI. Based on these features a diagnosis of focal amyotrophy was made. A cervical collar was prescribed and patient is under regular follow-up. CONCLUSION Hirayama disease is a rare self-limiting disease. Early diagnosis is necessary as the use of a simple cervical collar which will prevent neck flexion, has been shown to stop the progression.

  17. Effect evaluation of school entry immunization in the controlling vaccine preventing infectious diseases in schools/kindergartens%入学入托查验接种证对防控传染病效果评价

    Institute of Scientific and Technical Information of China (English)

    张大勇; 穆秋玥; 戴丽芳; 朱青

    2012-01-01

    95% and rise year by year and keep at a high level from 2004. Full coverage increased obviously after vaccination checks at schools and kindergartens, and the coverage increased in primary schools more than kindergartens. The replant completion rates of measles vaccine and DPT/DT vaccine after entry negatively correlated with the incidence of measles/pertussis and the percentage of measles outbreaks in primary schools/kindergartens, and it s statistically significant. Replant completion rate of HB vaccine of 3 -6 years old children after entry is without correlating with incidence of HB. But replant completion rate of HB vaccine of 7 - 12 years oLd children and incidence of HB is positively correlated. Conclusion Implementing school entry requirement standard and keeps the coverage of fully immunization at a high level could control effectively the incidence and outbreaks of vaccine preventing infectious diseases in schools/ kindergartens. It's necessary to replant Hepatitis B vaccine in the free range for improving immunization coverage. Proposal to Increase the vaccine varieties gradually into the school/nursery inspection.

  18. Learning about Crohn's Disease

    Science.gov (United States)

    ... genetic terms used on this page. Learning About Crohn's Disease What is Crohn's disease? What are the symptoms ... disease Additional Resources for Crohn's Disease What is Crohn's disease? Crohn's disease, an idiopathic (of unknown cause), chronic ...

  19. HIV and Rheumatic Disease

    Science.gov (United States)

    ... A Patient / Caregiver Diseases & Conditions HIV & Rheumatic Diseases HIV and Rheumatic Disease Fast Facts Rheumatic diseases related ... knows he or she has HIV. What are HIV-associated rheumatic diseases? Some diseases of the joints ...

  20. HIV and Rheumatic Disease

    Science.gov (United States)

    ... A Patient / Caregiver Diseases & Conditions HIV & Rheumatic Diseases HIV and Rheumatic Disease Fast Facts Rheumatic diseases related ... knows he or she has HIV. What are HIV-associated rheumatic diseases? Some diseases of the joints ...

  1. Niemann-Pick Disease

    Science.gov (United States)

    ... Disease] National Niemann-Pick Disease Foundation, Inc. National Tay-Sachs and Allied Diseases Association See all related ... Disease] National Niemann-Pick Disease Foundation, Inc. National Tay-Sachs and Allied Diseases Association See all related ...

  2. [Dupuytren disease].

    Science.gov (United States)

    Wagner, Pablo; Román, Javier A; Vergara, Jorge

    2012-09-01

    Dupuytren disease (DD) is a connective tissue disorder that consists in fibromatosis of the palmar and digital fascia (in form of nodules or flanges) that leads to the development of flexion contractures of the palm and fingers. The little and ring finger are particularly affected. The disease can limit hand function, reducing the quality of life. The disease can have a traumatic origin and is also associated with conditions such as diabetes mellitus, alcoholism, dyslipidemia, epilepsy and AIDS, among others. However, none of these conditions can fully explain the genesis of DD. A hereditary component is described in 40% of patients and is attributed to an autosomal dominant gene of variable penetrance, probably related to collagen synthesis. However there are also spontaneous and recessive inheritance cases. The diagnosis is clinical and based on physical examination. Treatment ranges from observation or use of injectable collagenase to the surgical option in cases with significant functional limitations.

  3. Celiac disease

    DEFF Research Database (Denmark)

    Hvas, Christian Lodberg; Jensen, Michael Dam; Reimer, Maria Christina;

    2015-01-01

    , which are found in wheat, rye, and barley. The disease prevalence is 0.5-1.0%, but CD remains under-diagnosed. The diagnosis relies on the demonstration of lymphocyte infiltration, crypt hyperplasia, and villous atrophy in duodenal biopsies. Serology, malabsorption, biochemical markers......This national clinical guideline approved by the Danish Society for Gastroenterology and Hepatology describes the diagnosis and treatment of celiac disease (CD) in adults. CD is a chronic immunemediated enteropathy of the small intestine triggered by the ingestion of gluten-containing proteins...... the small intestinal mucosa and absorption. Adherence to a GFD usually requires dietary advice from a clinical dietician. The monitoring of antibody levels and malabsorption markers is crucial during follow-up and allows for early treatment of disease complications. Important complications include...

  4. Myocardial disease

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    930497 Ectopic expression and the significanceof HLA—class II antigens in the myocardium ofpatients with dilated cardiomyopathy.LI Yunyou(李运友),et al.lst Affili Hosp,Nanjing MedCoil,Nanjing,210029.Chin J Cardiol 1993;21(1):15—16.Expression of HLA—class II antigens(DQ,DP)in the myocardium of patients with differentheart diseases and normal controls was studiedwith indirect immunofluorescence(IIF).Thepositive rates in different groups were observedas follows:dilated cardiomyopathy(DCM,12/13,+++),rheumatic heart disease(2/4,++),congenital heart diseases(1/14,+),left a-trial myxoma(0/1)and normal controls(1/8,

  5. Celiac disease

    DEFF Research Database (Denmark)

    Hvas, Christian Lodberg; Jensen, Michael Dam; Reimer, Maria Christina

    2015-01-01

    This national clinical guideline approved by the Danish Society for Gastroenterology and Hepatology describes the diagnosis and treatment of celiac disease (CD) in adults. CD is a chronic immunemediated enteropathy of the small intestine triggered by the ingestion of gluten-containing proteins......, which are found in wheat, rye, and barley. The disease prevalence is 0.5-1.0%, but CD remains under-diagnosed. The diagnosis relies on the demonstration of lymphocyte infiltration, crypt hyperplasia, and villous atrophy in duodenal biopsies. Serology, malabsorption, biochemical markers...... the small intestinal mucosa and absorption. Adherence to a GFD usually requires dietary advice from a clinical dietician. The monitoring of antibody levels and malabsorption markers is crucial during follow-up and allows for early treatment of disease complications. Important complications include...

  6. Dent's disease

    Directory of Open Access Journals (Sweden)

    Thakker Rajesh V

    2010-10-01

    Full Text Available Abstract Dent's disease is a renal tubular disorder characterized by manifestations of proximal tubule dysfunction, including low-molecular-weight proteinuria, hypercalciuria, nephrolithiasis, nephrocalcinosis, and progressive renal failure. These features are generally found in males only, and may be present in early childhood, whereas female carriers may show a milder phenotype. Prevalence is unknown; the disorder has been reported in around 250 families to date. Complications such as rickets or osteomalacia may occur. The disease is caused by mutations in either the CLCN5 (Dent disease 1 or OCRL1 (Dent disease 2 genes that are located on chromosome Xp11.22 and Xq25, respectively. CLCN5 encodes the electrogenic Cl-/H+ exchanger ClC-5, which belongs to the CLC family of Cl- channels/transporters. OCRL1 encodes a phosphatidylinositol bisphosphate (PIP2 5-phosphatase and mutations are also associated with Lowe Syndrome. The phenotype of Dent's disease is explained by the predominant expression of ClC-5 in the proximal tubule segments of the kidney. No genotype-phenotype correlation has been described thus far, and there is considerable intra-familial variability in disease severity. A few patients with Dent's disease do not harbour mutations in CLCN5 and OCRL1, pointing to the involvement of other genes. Diagnosis is based on the presence of all three of the following criteria: low-molecular-weight proteinuria, hypercalciuria and at least one of the following: nephrocalcinosis, kidney stones, hematuria, hypophosphatemia or renal insufficiency. Molecular genetic testing confirms the diagnosis. The differential diagnosis includes other causes of generalized dysfunction of the proximal tubules (renal Fanconi syndrome, hereditary, acquired, or caused by exogenous substances. Antenatal diagnosis and pre-implantation genetic testing is not advised. The care of patients with Dent's disease is supportive, focusing on the treatment of hypercalciuria and

  7. Celiac disease

    DEFF Research Database (Denmark)

    Hvas, Christian Lodberg; Jensen, Michael Dam; Reimer, Maria Christina;

    2015-01-01

    the small intestinal mucosa and absorption. Adherence to a GFD usually requires dietary advice from a clinical dietician. The monitoring of antibody levels and malabsorption markers is crucial during follow-up and allows for early treatment of disease complications. Important complications include......This national clinical guideline approved by the Danish Society for Gastroenterology and Hepatology describes the diagnosis and treatment of celiac disease (CD) in adults. CD is a chronic immunemediated enteropathy of the small intestine triggered by the ingestion of gluten-containing proteins...

  8. Hansen's disease: a vanishing disease?

    Directory of Open Access Journals (Sweden)

    Sinésio Talhari

    2012-12-01

    Full Text Available The introduction, implementation, successes and failures of multidrug therapy (MDT in all Hansen's disease endemic countries are discussed in this paper. The high efficacy of leprosy treatment with MDT and the global reduction of prevalence led the World Health Organization, in 1991, to establish the goal of elimination of Hansen's disease (less than 1 patient per 10,000 inhabitants to be accomplished by the year 2000. Brazil, Nepal and East Timor are among the few countries that didn't reach the elimination goal by the year 2000 or even 2005. The implications of these aspects are highlighted in this paper. Current data from endemic and previously endemic countries that carry a regular leprosy control programme show that the important fall in prevalence was not followed by the reduction of the incidence. This means that transmission of Mycobacterium leprae is still an issue. It is reasonable to conclude that we are still far from the most important goal of Hansen's disease control: the interruption of transmission and reduction of incidence. It is necessary to emphasize to health managers the need of keeping Hansen's disease control activities to better develop control programmes in the future. The recent international proposal to interrupt the transmission of leprosy by the year 2020 seems to unrealistic and it is discussed in this paper. The possibility of epidemiological impact related to the human immunodeficiency virus/Hansen's disease coinfection is also considered.

  9. Hansen's disease: a vanishing disease?

    Science.gov (United States)

    Talhari, Sinésio; Grossi, Maria Aparecida de Faria; Oliveira, Maria Leide W D R de; Gontijo, Bernardo; Talhari, Carolina; Penna, Gerson Oliveira

    2012-12-01

    The introduction, implementation, successes and failures of multidrug therapy (MDT) in all Hansen's disease endemic countries are discussed in this paper. The high efficacy of leprosy treatment with MDT and the global reduction of prevalence led the World Health Organization, in 1991, to establish the goal of elimination of Hansen's disease (less than 1 patient per 10,000 inhabitants) to be accomplished by the year 2000. Brazil, Nepal and East Timor are among the few countries that didn't reach the elimination goal by the year 2000 or even 2005. The implications of these aspects are highlighted in this paper. Current data from endemic and previously endemic countries that carry a regular leprosy control programme show that the important fall in prevalence was not followed by the reduction of the incidence. This means that transmission of Mycobacterium leprae is still an issue. It is reasonable to conclude that we are still far from the most important goal of Hansen's disease control: the interruption of transmission and reduction of incidence. It is necessary to emphasize to health managers the need of keeping Hansen's disease control activities to better develop control programmes in the future. The recent international proposal to interrupt the transmission of leprosy by the year 2020 seems to unrealistic and it is discussed in this paper. The possibility of epidemiological impact related to the human immunodeficiency virus/Hansen's disease coinfection is also considered.

  10. Myocardial disease

    Institute of Scientific and Technical Information of China (English)

    1992-01-01

    920666 Immunocytochemical study ofCuZn superoxide dismutase in the myocardi-um of normal subjects and patients ofrheumatic heart disease.ZHENG Yi(郑毅),et al. Dept Intern Med, Navy General Hosp,PLA, Beijing. 100037. Natl Med J China 1992;72(4): 225-227. By using the methods of immunocytochemistry

  11. Parkinson's disease

    DEFF Research Database (Denmark)

    Astradsson, Arnar; Aziz, Tipu Z

    2015-01-01

    -derived therapy in people with Parkinson's disease? We searched: Medline, Embase, The Cochrane Library and other important databases up to September 2014 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from...

  12. Wilson Disease

    Science.gov (United States)

    ... prevent organ damage. Changes in Eating, Diet, and Nutrition People with Wilson disease should reduce their dietary copper intake by avoiding foods that are high in copper, such as shellfish liver mushrooms nuts chocolate People should not eat these foods during the ...

  13. Mitochondrial Diseases

    Science.gov (United States)

    ... fats) that come from your food. When the mitochondria are defective, the cells do not have enough energy. The unused oxygen ... disease can vary. It depends on how many mitochondria are defective, and where ... organ, tissue, or cell type is affected. But often the problem affects ...

  14. Behcet's Disease

    Science.gov (United States)

    ... to stop taking the medicine suddenly, because the medicine alters the body’s production of the natural corticosteroid hormones. Long-term use of these medications can have side effects such as osteoporosis (a disease that leads to bone fragility), weight gain, delayed ...

  15. Huntington's disease

    DEFF Research Database (Denmark)

    Hjermind, Lena Elisabeth; Law, Ian; Jønch, Aia

    2011-01-01

    In this open-label pilot study, the authors evaluated the effect of memantine on the distribution of brain glucose metabolism in four Huntington's disease (HD) patients as determined by serial 18-fluoro-deoxyglucose [F(18)]FDG-PET scans over a period of 3-4 months (90-129 days, with one patient...

  16. Parkinson disease

    Science.gov (United States)

    In Parkinson disease, dopamine production becomes irregular and inadequate and nerve cells cannot properly transmit messages. This results in the loss of muscle function. By providing an even, adequate supply of medication that the body converts into dopamine, neurons are able to transmit ...

  17. Meningococcal disease

    Directory of Open Access Journals (Sweden)

    Alex Koyfman

    2011-12-01

    Full Text Available The first cases of meningococcal meningitis were described in Geneva in 1805 and in New England in 1806, the causative agent finally being identified by Anton Weichselbaum in 1887. The first meningococcal epidemics occurred in sub-Saharan Africa in the early 1900s and periodic outbreaks continue to occur worldwide today. Neisseria meningitidis colonizes the naso-oropharyngeal mucosa in approximately 10–20% of healthy individuals. When it invades the bloodstream, meningococcus has the potential to cause devastating disease. It can affect people of any age, but primarily infects children and adolescents. Meningococcemia classically follows an upper respiratory illness consisting of myalgias, fever, headache, and nausea. It can present as an indolent infection with rapid recovery or progress within a few hours into a fulminant illness affecting multiple organ systems. As such, meningococcemia is one of the important causes of sepsis. Prior to antibiotic therapy, the disease carried a 70% mortality rate. Despite advances in early diagnosis and treatment, 10–15% of affected patients die from the disease and another 10–20% are left with severe morbidities (neurologic disability, hearing loss, loss of a limb. Meningococcal disease remains a significant global health threat.

  18. Lung Diseases

    Science.gov (United States)

    When you breathe, your lungs take in oxygen from the air and deliver it to the bloodstream. The cells in your body need oxygen to ... you breathe nearly 25,000 times. People with lung disease have difficulty breathing. Millions of people in ...

  19. INFECTIOUS DISEASE

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    2.1 Viral disease2003263 Isolation, identification and sequence analyses of dengue virus type 2 strain GD19/2001. REN Rui-wen(任瑞文), et al. Milit Med Instit Guangzhou Milit District, Guangzhou 510507. Chin J Epidemiol 2003; 24 (4):288-290. Objective:To identify the virus isolated from patients

  20. INFECTIOUS DISEASE

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    3.1 Viral disease2004310 One-step simultaneous detection of G-genotype of human group a rotaviruses by multiplex RT-PCR. TANG Shaowen (唐少文) , et al. Dept Epidemiol, Tongji Med Coll Huozhong Univ Sci & Technol, Wuhan 430030. Chin J Lab Med 2004; 27 (4):234-236

  1. INFECTIOUS DISEASE

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    4. 1 Viral disease2004174 Study on the seropositive prevalence of humanimmunodeficiency virus in a village residents living in rural region of central China. CHENG Hua (程华), et al. Public Health Sch, Fudan Univ, Shanghai 200032. Chin J Epidemiol 2004;25(4):317 -321.

  2. Huntington's Disease

    Science.gov (United States)

    ... seizures. More than 30,000 Americans have HD. Huntington’s disease is caused by a mutation in the gene for a protein called huntingtin. The defect causes the cytosine, adenine, and guanine (CAG) building blocks of DNA to repeat many more ...

  3. Huntington disease

    Science.gov (United States)

    ... President of the Florida Society of Neurology (FSN). Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Huntington's Disease Read more Latest Health News Read more Health ...

  4. Prionic diseases

    Directory of Open Access Journals (Sweden)

    Abelardo Q-C Araujo

    2013-09-01

    Full Text Available Prion diseases are neurodegenerative illnesses due to the accumulation of small infectious pathogens containing protein but apparently lacking nucleic acid, which have long incubation periods and progress inexorably once clinical symptoms appear. Prions are uniquely resistant to a number of normal decontaminating procedures. The prionopathies [Kuru, Creutzfeldt-Jakob disease (CJD and its variants, Gerstmann-Sträussler-Scheinker (GSS syndrome and fatal familial insomnia (FFI] result from accumulation of abnormal isoforms of the prion protein in the brains of normal animals on both neuronal and non-neuronal cells. The accumulation of this protein or fragments of it in neurons leads to apoptosis and cell death. There is a strong link between mutations in the gene encoding the normal prion protein in humans (PRNP - located on the short arm of chromosome 20 – and forms of prion disease with a familial predisposition (familial CJD, GSS, FFI. Clinically a prionopathy should be suspected in any case of a fast progressing dementia with ataxia, myoclonus, or in individuals with pathological insomnia associated with dysautonomia. Magnetic resonance imaging, identification of the 14-3-3 protein in the cerebrospinal fluid, tonsil biopsy and genetic studies have been used for in vivo diagnosis circumventing the need of brain biopsy. Histopathology, however, remains the only conclusive method to reach a confident diagnosis. Unfortunately, despite numerous treatment efforts, prionopathies remain short-lasting and fatal diseases.

  5. INFECTIOUS DISEASE

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    3.1 Viral disease2003162 The clinical and epidemiological analysis on 46 patients with epidemic hemorrhagic fever in Huainan areas. WANG Kexia(王克霞). Sch Med, An-hui Univ Sci & Tehnol, Huainan 232001. Chin J En-demiol 2003;22(1):48-50.

  6. Extraphyramidal disease

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    2009250 Effects of bilateral deep brain stimulation of the subthalamic nucleus on depression in patients with parkinson’s disease. WANG Xuelian(王学廉),et al.Dept Neurosurg,Tangdu Hosp,4th Milit Med Univ,Xi’an,710038.Chin J Nerv Ment Dis,2009;35(2):88-92.

  7. Chagas Disease

    Science.gov (United States)

    ... contact with an infected triatomine bug also called “kissing bug,”“benchuca,” “vinchuca,”“chinche,”or “barbeiro” Who can ... get Chagas disease? ■ Usually from contact with a kissing bug ■ After the kissing bug bites, it poops. ...

  8. Neurodegenerative disorders: Parkinson's disease and Huntington's disease

    Science.gov (United States)

    Hague, S; Klaffke, S; Bandmann, O

    2005-01-01

    Parkinson's disease and Huntington's disease are both model diseases. Parkinson's disease is the most common of several akinetic-rigid syndromes and Huntington's disease is only one of an ever growing number of trinucleotide repeat disorders. Molecular genetic studies and subsequent molecular biological studies have provided fascinating new insights into the pathogenesis of both disorders and there is now real hope for disease modifying treatment in the not too distant future for patients with Parkinson's disease or Huntington's disease. PMID:16024878

  9. Neurodegenerative disorders: Parkinson's disease and Huntington's disease.

    Science.gov (United States)

    Hague, S M; Klaffke, S; Bandmann, O

    2005-08-01

    Parkinson's disease and Huntington's disease are both model diseases. Parkinson's disease is the most common of several akinetic-rigid syndromes and Huntington's disease is only one of an ever growing number of trinucleotide repeat disorders. Molecular genetic studies and subsequent molecular biological studies have provided fascinating new insights into the pathogenesis of both disorders and there is now real hope for disease modifying treatment in the not too distant future for patients with Parkinson's disease or Huntington's disease.

  10. Infectious Disease

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    3.1 Viral disease2007149 Study on platelet β3 integrin expression levels and their relationships with disease severity in patients with hemorrhagic fever with renal syndrome.GAO Maicang(高麦仓), et al. Dept Infect Dis, 1st Affili Hosp, Sch Med, Xi′an Jiaotong Univ , Xi′an 710061. Chin J Infect Dis 2007;25(3):152-153. Objective To investigate the relationship between the expression level of platelet membrane glycoprotein 133(GP Ⅲa, CD61) and the severity of disease in patients with hemorrhagic fever with renal syndrome(HFRS). Methods One hundred and four patients with HFRS and 30 healthy individuals were recruited. The percentage of CD61 positive platelets and the mean fluorescence intensities (MFI) of platelet membrane glycoprotein β3 were determined by flow cytometry (FCM). The 104 patients studied were divided into three groups based on their expression levels of platelet membrane glycoprotein β3 at oliguric phase. Clinical data and laboratory parameters in different groups were compared and analyzed. Results The expression levels of CD61 in patients with HFRS were significantly higher than those in control group, although no significant difference in the percentage of CD61 positive platelets between patients with HFRS and controls was detected. The MFI of CD61 expression in patients with HFRS at fever phase, oliguric phase and polyuric phase was 19. 75±2.57, 17.46±1.48 and 15. 55±0.60, respectively, which was significantly higher than that in control group (3. 20±0.12). The expression level of CD61 in patients with HFRS at oliguric phase was negatively correlated with platelet count and serum albumin(r=-0.637 and -0. 695. respectively) and positively correlated with white blood cell count, blood urea nitrogen, serum creatinine and alanine aminotransferase(r= 0.945, 0. 904, 0.956 and 0. 891, respectively). When the patients were compared according to the expression levels of CD61, it was indicated that the higher the expression level of CD61, the

  11. Celiac disease

    Institute of Scientific and Technical Information of China (English)

    Luis Rodrigo

    2006-01-01

    Celiac disease (CD) is a common autoimmune disorder,induced by the intake of gluten proteins present in wheat, barley and rye. Contrary to common belief,this disorder is a protean systemic disease, rather than merely a pure digestive alteration. CD is closely associated with genes that code HLA-Ⅱ antigens, mainly of DQ2 and DQ8 classes. Previously, it was considered to be a rare childhood disorder, but is actually considered a frequent condition, present at any age, which may have multiple complications. Tissue transglutaminase-2(tTG), appears to be an important component of this disease, both, in its pathogenesis and diagnosis. Active CD is characterized by intestinal and/or extra-intestinal symptoms, villous atrophy and crypt hyperplasia, and strongly positive tTG auto-antibodies. The duodenal biopsy is considered to be the "gold standard" for diagnosis, but its practice has significant limitations in its interpretation, especially in adults. Occasionally, it results in a false-negative because of patchy mucosal changes and the presence of mucosal villous atrophy is often more severe in the proximal jejunum, usually not reached by endoscopic biopsies. CD is associated with increased rates of several diseases, such as iron deficiency anemia, osteoporosis, dermatitis herpetiformis,several neurologic and endocrine diseases, persistent chronic hypertransami-nasemia of unknown origin,various types of cancer and other autoimmune disorders.Treatment of CD dictates a strict, life-long gluten-free diet, which results in remission for most individuals,although its effect on some associated extraintestinal manifestations remains to be established.

  12. Bacterial disease

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    930445 A report on investigation of an outbreakof legionnaires’disease in a hotel in Beijing.DENG Changying(邓长英),et al.Beijing ArmedForce General Hosp,Beijing,100027.Chin J Epi-demiol 1993;14(2):78—79.During the period from February to March,1992,an outbreak of upper respiratory infection(influenza—like syndrome)took place in a hotelin Beijing.An epidemiological investigation andbacteriological examination were carried out inthis hotel.The results showed that it was anoutbreak of Legionnaires’disease caused by Le-gionella pneumophila serogroup 10(Lpl0).Theincidence was 13.51%(5/37).This is the firstreport on Lp10 infection in China.

  13. Parkinson's disease

    DEFF Research Database (Denmark)

    Astradsson, Arnar; Aziz, Tipu Z

    2015-01-01

    INTRODUCTION: The mean age of onset of Parkinson's disease is about 65 years, with a median time of 9 years between diagnosis and death. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of fetal cell or stem cell......-derived therapy in people with Parkinson's disease? We searched: Medline, Embase, The Cochrane Library and other important databases up to September 2014 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from...... relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). RESULTS: We found two studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. CONCLUSIONS...

  14. Menkes disease.

    Science.gov (United States)

    Tümer, Zeynep; Møller, Lisbeth B

    2010-05-01

    Menkes disease (MD) is a lethal multisystemic disorder of copper metabolism. Progressive neurodegeneration and connective tissue disturbances, together with the peculiar 'kinky' hair are the main manifestations. MD is inherited as an X-linked recessive trait, and as expected the vast majority of patients are males. MD occurs due to mutations in the ATP7A gene and the vast majority of ATP7A mutations are intragenic mutations or partial gene deletions. ATP7A is an energy dependent transmembrane protein, which is involved in the delivery of copper to the secreted copper enzymes and in the export of surplus copper from cells. Severely affected MD patients die usually before the third year of life. A cure for the disease does not exist, but very early copper-histidine treatment may correct some of the neurological symptoms.

  15. Morgellons disease?

    Science.gov (United States)

    Accordino, Robert E; Engler, Danielle; Ginsburg, Iona H; Koo, John

    2008-01-01

    Morgellons disease, a pattern of dermatologic symptoms very similar, if not identical, to those of delusions of parasitosis, was first described many centuries ago, but has recently been given much attention on the internet and in the mass media. The present authors present a history of Morgellons disease, in addition to which they discuss the potential benefit of using this diagnostic term as a means of building trust and rapport with patients to maximize treatment benefit. The present authors also suggest "meeting the patient halfway" and creating a therapeutic alliance when providing dermatologic treatment by taking their cutaneous symptoms seriously enough to provide both topical ointments as well as antipsychotic medications, which can be therapeutic in these patients.

  16. Lyme Disease.

    Science.gov (United States)

    Hu, Linden T

    2016-05-03

    This issue provides a clinical overview of Lyme disease, focusing on prevention, diagnosis, treatment, and practice improvement. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including MKSAP (Medical Knowledge and Self-Assessment Program). Annals of Internal Medicine editors develop In the Clinic in collaboration with the ACP's Medical Education and Publishing divisions and with the assistance of additional science writers and physician writers.

  17. Ledderhose Disease

    Science.gov (United States)

    Fausto de Souza, Dominique; Micaelo, Lilian; Cuzzi, Tullia

    2010-01-01

    Plantar fibromatosis, or Ledderhose disease, is a rare hyperproliferative disorder of the plantar aponeurosis. It may occur at any age with the greatest prevalence at middle age and beyond. This disorder is more common in men than woman and it is sometimes associated with other forms of fibromatosis. A 28-year-old Brazilian woman with a six-year history of painless bilateral plantar nodules is described in this article. PMID:20877526

  18. INFECTIOUS DISEASE

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    4.1 Viral disease2003021 Analysis on the epidemiologic features of Dengue fever in Guangdong province, 1990 - 2000. LUO Huiming(罗会明), et al. Dis Contr & Prev Center Guangdong Prov, Guangzhou 510300. Chin J Epi-demiol 2002;23(6):427-430.Objective: To determine the epidemiological characteristics and risk factors of Dengue fever in Guangdong province in 1990 - 2000, and to develop the strategy for

  19. Fungal disease

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    930031 Experimental studies on lung lesionsof rabbits caused by streptomyces thermohy-groscopicus.LIU Fang(刘仿),et al.Dept Mi-crobiol,Hubei Med Coll,Xianning Branch,437100.Chin J Tuberc & Respir Dis 1992;15(4):207—208.Imitating the natural way of infection ofFarmer’s lung disease,we succeeded in inducingChina Medical Abstracts(Internal Medicine)

  20. Wilson's disease.

    Science.gov (United States)

    Loudianos, G; Gitlin, J D

    2000-01-01

    Wilson's disease is an autosomal recessive disorder of copper metabolism resulting from the absence or dysfunction of a copper transporting P-type ATPase encoded on chromosome 13. This ATPase is expressed in hepatocytes where it is localized to the trans-Golgi network and transports copper into the secretory pathway for incorporation into ceruloplasmin and excretion into the bile. Under physiologic circumstances, biliary excretion represents the sole mechanism for copper excretion, and thus affected individuals have progressive copper accumulation in the liver. When the capacity for hepatic storage is exceeded, cell death ensues with copper release into the plasma, hemolysis, and tissue deposition. Presentation in childhood may include chronic hepatitis, asymptomatic cirrhosis, or acute liver failure. In young adults, neuropsychiatric symptoms predominate and include dystonia, tremor, personality changes, and cognitive impairments secondary to copper accumulation in the central nervous system. The laboratory diagnosis of Wilson's disease is confirmed by decreased serum ceruloplasmin, increased urinary copper content, and elevated hepatic copper concentration. Molecular genetic analysis is complex as more than 100 unique mutations have been identified and most individuals are compound heterozygotes. Copper chelation with penicillamine is an effective therapy in most patients and hepatic transplantation is curative in individuals presenting with irreversible liver failure. Elucidation of the molecular genetic basis of Wilson's disease has permitted new insights into the mechanisms of cellular copper homeostasis.

  1. Polycystic Kidney Disease

    Science.gov (United States)

    ... Kidney Disease Polycystic Kidney Disease (PKD) Related Topics Section Navigation Kidney Disease Acquired Cystic Kidney Disease Amyloidosis & ... for a Child with Kidney Disease Ectopic Kidney Medullary Sponge Kidney Kidney Dysplasia Kidney Failure Choosing a ...

  2. Coronary heart disease

    Science.gov (United States)

    Heart disease, Coronary heart disease, Coronary artery disease; Arteriosclerotic heart disease; CHD; CAD ... slow down or stop. A risk factor for heart disease is something that increases your chance of getting ...

  3. Parkinson's Disease Dementia

    Science.gov (United States)

    ... Find your local chapter Join our online community Parkinson's Disease Dementia Parkinson's disease dementia is an impairment in ... disease. About Symptoms Diagnosis Causes & risks Treatments About Parkinson's disease dementia The brain changes caused by Parkinson's disease ...

  4. [Goodpasture disease].

    Science.gov (United States)

    Fomegné, G; Dratwa, M; Wens, R; Mesquita, M; Van der Straaten, M; Vanden Haute, K; Fosso, C

    2006-01-01

    We report one case of acute renal failure with oliguria, microscopic haematuria and normocytic anemia in a 86-year old Swedish woman. A full investigation led to the diagnosis of Goodpasture disease, an isolated form of Goodpasture syndrome. Goodpasture disease is and autoimmune disorder characterized by the development of autoantibodies to the NC1 domain of the alpha3 chain of type IV collagen, found mainly in glomerular basement membranes (GBM). When the disease affects both the lung and the kidney, it is called Goodpasture syndrome but the pulmonary or renal involvement can be isolated or separated in years. Its pathogenesis is not well known. It occurs essentially in Caucasian subjects, preferentially from Nordic and Anglo-Saxon countries (higher prevalence of HLA DR B1-15 and B1-4 group). Are also mentioned, the exposure to hydrocarbons, rustproof, insecticides and greasy solvents. The annual incidence of Goodpasture syndrome is rare and has been estimated in Europe to be about 0.5 to 1 case per million inhabitants. The isolated renal form represents about 1/3 of the cases. The clinical presentation is characterized by rapidly progressive renal failure with oliguria or anuria and in case of lung involvement, pulmonary hemorrhage responsible of hemoptysis, sometimes massive. Renal biopsy and immunofluorescence analysis play a key role in the diagnosis. The presence of both linear deposits of IgG along the glomerular basement membrane (GBM) and circulating anti-GBM antibodies is of paramount importance. The treatment, which depends on the degree of renal involvement, is based on the association of corticosteroids, cyclophosphamide and plasma exchanges.

  5. Celiac disease

    DEFF Research Database (Denmark)

    Hvas, Christian Lodberg; Jensen, Michael Dam; Reimer, Maria Christina

    2015-01-01

    This national clinical guideline approved by the Danish Society for Gastroenterology and Hepatology describes the diagnosis and treatment of celiac disease (CD) in adults. CD is a chronic immunemediated enteropathy of the small intestine triggered by the ingestion of gluten-containing proteins......, and identification of specific HLA haplotypes may contribute to CD diagnosis. Classical CD presents with diarrhoea and weight loss, but non-classical CD with vague or extraintestinal symptoms is common. The treatment for CD is a lifelong gluten-free diet (GFD), which, in the majority of patients, normalises...

  6. Menkes disease

    DEFF Research Database (Denmark)

    Tümer, Zeynep; Møller, Lisbeth B

    2010-01-01

    of patients are males. MD occurs due to mutations in the ATP7A gene and the vast majority of ATP7A mutations are intragenic mutations or partial gene deletions. ATP7A is an energy dependent transmembrane protein, which is involved in the delivery of copper to the secreted copper enzymes and in the export......Menkes disease (MD) is a lethal multisystemic disorder of copper metabolism. Progressive neurodegeneration and connective tissue disturbances, together with the peculiar 'kinky' hair are the main manifestations. MD is inherited as an X-linked recessive trait, and as expected the vast majority...

  7. Menkes disease

    OpenAIRE

    Tümer, Zeynep; Møller, Lisbeth B

    2009-01-01

    Menkes disease (MD) is a lethal multisystemic disorder of copper metabolism. Progressive neurodegeneration and connective tissue disturbances, together with the peculiar ‘kinky' hair are the main manifestations. MD is inherited as an X-linked recessive trait, and as expected the vast majority of patients are males. MD occurs due to mutations in the ATP7A gene and the vast majority of ATP7A mutations are intragenic mutations or partial gene deletions. ATP7A is an energy dependent transmembrane...

  8. Celiac disease.

    Science.gov (United States)

    Polanco, Isabel

    2008-08-01

    Celiac disease is an immunologically mediated enteropathy of the small intestine, characterized by lifelong intolerance to the gliadin and related prolamines from wheat and other cereals, that occurs in genetically predisposed individuals. Symptoms result from structural damage to the mucosa of the small intestine, which may cause malabsorption with positive autoantibodies in the sera. Normal mucosal architecture is restored after the use of a gluten-free diet and the normalization of the autoantibodies. Villous atrophy and high levels of autoantibodies reappear when gluten is reintroduced into the diet (gluten challenge).

  9. Infectious Disease

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    2.1 Viral disease 2006009 Correlation analysis of type A influenza virus genetic variation characteristic with survival selective pressure ZHOU xiao -ming(周晓明 ) ,et al. Sch Pub Health,Fudan Univ. Shanghai 200032. China J Infect Dis 2005;23(4) :221 -224 Objective:To study the relationship betweer. type A influenza virus genetic variation with survival selective pressure to find possible vaccine conserved antigen target. Methods:Seven strains of same HA (Hemagglutinin) serotype, regional and isolation time closely related type A influenza virus were selected with full HA gene coding sequence , Blast2 program was used to calculate the param-

  10. Women's Heart Disease: Heart Disease Risk Factors

    Science.gov (United States)

    ... this page please turn JavaScript on. Feature: Women's Heart Disease Heart Disease Risk Factors Past Issues / Winter 2014 Table of ... or habits may raise your risk for coronary heart disease (CHD). These conditions are known as risk factors. ...

  11. Crohn disease - children - discharge

    Science.gov (United States)

    Inflammatory bowel disease in children - Crohn disease; IBD in children - Crohn disease; Regional enteritis - children; Ileitis - children; Granulomatous ileocolitis - children; Colitis in children; CD - children

  12. Infectious diseases and arthropods

    National Research Council Canada - National Science Library

    Goddard, Jerome

    2000-01-01

    .... His book covers mosquito-, tick-, and flea-borne diseases, and a variety of other miscellaneous vector-borne diseases, including Chagas' disease, African sleeping sickness, onchocerciasis, scrub...

  13. Parkinson's Disease Videos

    Medline Plus

    Full Text Available ... of Parkinson's Disease OHSU - Parkinson's Disease: Managing Depression, Anxiety & Psychosis OHSU - Parkinson's Disease: Pharmacological Management of Depression, Anxiety & Psychosis OHSU - Therapeutic ...

  14. Hirayama disease

    Directory of Open Access Journals (Sweden)

    Atul T Tayade

    2010-01-01

    Full Text Available A 17-year-old male, who gave up his favorite sport cricket and started playing football, presented with one-year history of slowly progressive atrophic weakness of forearms and hands. Neurological examination showed weak and wasted arms, forearms and hand but no evidence of pyramidal tract, spinothalmic tract and posterior column lesions. Plain cervical spine radiographs showed no abnormal findings. Cervical magnetic resonance imaging (MRI showed asymmetric cord atrophy; images obtained with neck flexed showed the anterior shifting of the posterior wall of the lower cervical dural sac resulting in cord compression. These findings suggest Hirayama disease, a kind of cervical myelopathy related to the flexion movements of the neck.

  15. Research on the psychological stress theory-based psychological intervention′s appli-cation effect on the emotion management of finger replantation patients%以心理应激理论为基础的心理干预策略在断指再植术后早期患者情绪管理中的应用效果研究

    Institute of Scientific and Technical Information of China (English)

    陆正荣; 马晓煜

    2016-01-01

    Objective To evaluate the effectiveness of the psychological stress theory-based psychological in-tervention on emotion management of finger replantation patients. Methods The study was a quasi-experimental stud-y. The patients were divided into the intervention group ( n=50 ) and the control group ( n=46 ) according to the admis-sion time. The intervention group received psychological stress theory-based psychological intervention, while the control group received general management. The psychological state of the patients should be evaluated 2 weeks before the inter-vention and after surgery, so as to evauluate the effectiveness of the intervention strategy. Results The scores of SCL-90 in most dimensions and HADS had decreased after the intervention in intervention group, the differences were statis-tically significant ( P<0. 05 ); the scores of SCL-90 in most dimensions and HADS of the intervention group were signif-icantly lower than those of the control group, the differences were statistically significant (P<0. 05) . Conclusion The psychological stress theory-based psychological intervention can significantly improve patients′negative emotions.%目的:以心理应激理论为基础制定心理干预策略,评价该策略在管理断指再植患者术后早期负性情绪的效果。方法采用历史对照类实验研究法根据患者的入院时间将患者分为干预组(50例)和对照组(46例)。干预组患者采用以应激理论为基础制定的心理干预策略,对照组实行常规护理。于干预前和术后2周对患者的心理状态进行评估,从而评价该干预策略的有效性。结果干预组干预后症状自评量表( SCL-90)多个维度得分和医院焦虑抑郁(HADS)两个分量表得分均明显低于干预前,差异具有统计学意义(P<0.05);干预后,干预组患者症状自评量表(SCL-90)多个维度得分和医院焦虑抑郁(HADS)两个分量表得分均明显低于对照

  16. [Bone disease in Gaucher's disease].

    Science.gov (United States)

    Roca Espiau, Mercedes

    2011-09-01

    The exposition aims, is to review the pathophysiological mechanisms of bone marrow involvement and the patterns of marrow infiltration by Gaucher cells. We have reviewed the different methods of assessment of bone marrow infiltration and its temporal development. Qualitative methods include simple radiography, magnetic resonance imaging (MRI), computed tomography (CT) and radioisotope. The simple radiography is the basic element, but its sensitivity is limited and only allows for assessing changes and trabecular bone remodeling MRI allows us to appreciate the bone marrow infiltration, detection of complications and response to therapy. Radioisotopes can contribute to the differential diagnosis of osteomyelitis and bone crises. Among the quantitative methods are the QCSI (quantitative chemical shift imaging) and the dual-energy X-ray absorptiometry (DEXA), as well as new quantitative techniques of CT, MRI and ultrasound densitometry. The QCSI performed an assessment of fat content of bone marrow in the spine. DEXA quantifies bone density by measuring the attenuation coefficient. The semiquantitative methods have various "scores" to establish criteria for generalized bone disease endpoints of disease progression and response to therapy.

  17. Undifferentiated Connective Tissue Disease

    Science.gov (United States)

    ... Home Conditions Undifferentiated Connective Tissue Disease (UCTD) Undifferentiated Connective Tissue Disease (UCTD) Make an Appointment Find a Doctor ... L. Goldstein, MD, MMSc (February 01, 2016) Undifferentiated connective tissue disease (UCTD) is a systemic autoimmune disease. This ...

  18. Associated Autoimmune Diseases

    Science.gov (United States)

    ... gland in the neck, thick and coarse hair. Addison’s Disease Arare disease involving the adrenal gland. The prevalence of celiac disease in people with addison’s disease is significant. Symptoms of Addison’s may include weight ...

  19. Genetics and Rheumatic Disease

    Science.gov (United States)

    ... Well with Rheumatic Disease Genetics and Rheumatic Disease Genetics and Rheumatic Disease Fast Facts Studying twins has ... 70%, and for non-identical pairs, even lower. Genetics and ankylosing spondylitis Each rheumatic disease has its ...

  20. Chronic Beryllium Disease

    Science.gov (United States)

    ... Science Education & Training Home Conditions Chronic Beryllium Disease Chronic Beryllium Disease Make an Appointment Find a Doctor ... MD, MSPH, FCCP (February 01, 2016) What is chronic beryllium disease (CBD)? Chronic beryllium disease (CBD) is ...

  1. Heart disease - risk factors

    Science.gov (United States)

    Heart disease - prevention; CVD - risk factors; Cardiovascular disease - risk factors; Coronary artery disease - risk factors; CAD - risk ... a certain health condition. Some risk factors for heart disease you cannot change, but some you can. ...

  2. Inflammation and Heart Disease

    Science.gov (United States)

    ... Disease Venous Thromboembolism Aortic Aneurysm More Inflammation and Heart Disease Updated:Oct 12,2016 Understand the risks of ... inflammation causes cardiovascular disease, inflammation is common for heart disease and stroke patients and is thought to be ...

  3. Lipid Storage Diseases

    Science.gov (United States)

    ... age 2, usually from lung disease. Children with Tay-Sachs and Sandhoff diseases often die at an ... age 2, usually from lung disease. Children with Tay-Sachs and Sandhoff diseases often die at an ...

  4. Heart disease and women

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/007188.htm Heart disease and women To use the sharing features on ... please enable JavaScript. People often DO NOT consider heart disease a woman's disease. Yet cardiovascular disease is the ...

  5. Men and Heart Disease

    Science.gov (United States)

    ... Pressure Salt Cholesterol Million Hearts® WISEWOMAN Men and Heart Disease Fact Sheet Recommend on Facebook Tweet Share Compartir Source: Interactive Atlas of Heart Disease and Stroke Heart Disease Facts in Men Heart disease is the leading ...

  6. American Lyme Disease Foundation

    Science.gov (United States)

    ... Infectious Diseases, 35: 451-464, 2002) What is Lyme Disease? Lyme disease (LD) is an infection caused by ... mission with your own tax-deductible contribution. American Lyme Disease Foundation, Inc. PO Box 466 Lyme, CT 06371 ...

  7. Thyroid Disease (for Parents)

    Science.gov (United States)

    ... Teaching Kids to Be Smart About Social Media Thyroid Disease KidsHealth > For Parents > Thyroid Disease Print A ... many other parts of the body. What Is Thyroid Disease? Thyroid disease is when the thyroid gland ...

  8. Thyroid Disease and Teens

    Science.gov (United States)

    ... Surgery? Choosing the Right Sport for You Shyness Thyroid Disease KidsHealth > For Teens > Thyroid Disease Print A ... other parts of your body. continue What Is Thyroid Disease? Thyroid disease occurs when the thyroid gland ...

  9. Genetics and Rheumatic Disease

    Science.gov (United States)

    ... Well with Rheumatic Disease Genetics and Rheumatic Disease Genetics and Rheumatic Disease Fast Facts Studying twins has ... 70%, and for non-identical pairs, even lower. Genetics and ankylosing spondylitis Each rheumatic disease has its ...

  10. Pelvic Inflammatory Disease (PID)

    Science.gov (United States)

    ... Management Education & Events Advocacy For Patients About ACOG Pelvic Inflammatory Disease (PID) Home For Patients Search FAQs Pelvic Inflammatory ... Inflammatory Disease (PID) FAQ077, September 2015 PDF Format Pelvic Inflammatory Disease (PID) Gynecologic Problems What is pelvic inflammatory disease ( ...

  11. Thyroid Disease (for Parents)

    Science.gov (United States)

    ... Old Feeding Your 1- to 2-Year-Old Thyroid Disease KidsHealth > For Parents > Thyroid Disease A A ... many other parts of the body. What Is Thyroid Disease? Thyroid disease is when the thyroid gland ...

  12. Thyroid Disease and Teens

    Science.gov (United States)

    ... Loss Surgery? A Week of Healthy Breakfasts Shyness Thyroid Disease KidsHealth > For Teens > Thyroid Disease A A ... other parts of your body. continue What Is Thyroid Disease? Thyroid disease occurs when the thyroid gland ...

  13. Sickle Cell Disease

    Science.gov (United States)

    ... sickle cell disease?Sickle cell disease, also called sickle cell anemia, is a hereditary condition (which means it runs ... disease, hemoglobin SS disease, hemoglobin synthesis, hemoglobinopathies, ... cell anemia, sickle cell crisis, vaso-occlusive crisis Family Health, ...

  14. Gaucher Disease in Pregnancy

    Science.gov (United States)

    ... from your health care provider. What is Gaucher disease? Gaucher disease is a genetic disorder. People with Gaucher ... severe and depend on the type of Gaucher disease. Gaucher disease occurs in approximately 1 in 60,000 ...

  15. Aortic Valve Disease

    Science.gov (United States)

    ... Tricuspid Valve Disease Cardiac Rhythm Disturbances Thoracic Aortic Aneurysm Pediatric and Congenital Heart Disease Heart abnormalities that are ... Transplantation End-stage Lung Disease Adult Lung Transplantation Pediatric Lung ... Aortic Aneurysm Aortic Valve Disease Overview The human heart has ...

  16. What Is Vascular Disease?

    Science.gov (United States)

    ... Donors Corporate Sponsors Donor Privacy Policy What Is Vascular Disease? What Is Vascular Disease? Vascular disease is any abnormal condition of ... steps to prevent vascular disease here. Understanding the Vascular System Your vascular system – the highways of the ...

  17. Parkinson's disease.

    Science.gov (United States)

    Benninger, David H

    2013-01-01

    In advanced Parkinson's disease (PD), the emergence of symptoms refractory to conventional therapy poses therapeutic challenges. The success of deep brain stimulation (DBS) and advances in the understanding of the pathophysiology of PD have raised interest in noninvasive brain stimulation as an alternative therapeutic tool. The rationale for its use draws from the concept that reversing abnormalities in brain activity and physiology thought to cause the clinical deficits may restore normal functioning. Currently the best evidence in support of this concept comes from DBS, which improves motor deficits, and modulates brain activity and motor cortex physiology, although whether a causal interaction exists remains largely undetermined. Most trials of noninvasive brain stimulation in PD have applied repetitive transcranial magnetic stimulation (rTMS), targeting the motor cortex. Current studies suggest a possible therapeutic potential for rTMS and transcranial direct current stimulation (tDCS), but clinical effects so far have been small and negligible with regard to functional independence and quality of life. Approaches to potentiate the efficacy of rTMS include increasing stimulation intensity and novel stimulation parameters that derive their rationale from studies on brain physiology. These novel parameters are intended to simulate normal firing patterns or to act on the hypothesized role of oscillatory activity in the motor cortex and basal ganglia with regard to motor control and its contribution to the pathogenesis of motor disorders. Noninvasive brain stimulation studies will enhance our understanding of PD pathophysiology and might provide further evidence for potential therapeutic applications.

  18. [Castleman disease].

    Science.gov (United States)

    Belletti, Gerardo A; Savio, Verónica; Minoldo, Daniel; Caminos, Susana; Yorio, Marcelo A

    2004-01-01

    A 66 years female, who was since last year under astenia, arthralgias, pimply lesions in spread plates and tests showing eritrosedimentation over 100 mm, anemi, leucocitosis with neutrofilia, policlonal hypergammaglobulinemia, slight proteinuria and IgE on 900. This patient was sporadically treated with corticoids. When made the medical consult had lost 34lb., was under anorexy, as well as dyspepsia. Hemoglobyn 6.9 gr/dl, leucocytes 20000/mm3, neutrofils at 90%, proteinogram the same as former, with hypoalbuminemia. She was taking prednisona, 16 mg/day. When examined showed depress of conscience, astenia, and dermic lesions already quoted. 4 cm nonpainful right axillary adenopaty adhered to deep planes. Medulogram with increased iron, hyperegenerative. Ganglionar biopsia: linfoid hyperplasic process linked to inmune response. Toracoabdominal tomography with adenomegalia in torax and retroperitoneo. Skin biopsia: neutrofilic vasculitis. The patient suspends the 16 mg of prednisona and fever as well as generalized adenopatias come up. After laying aside other ethiologies, and understanding as Castleman Multicentric disease, it is started to supply prednisona 1 mg/kg of weight with a clinical and biochemical fast and outstanding response. After 7 months it was progressively suspended the esteroids and 60 days later, the process fall back; for that, corticoids are restarted, with a good evolution. The illness of Castleman although it is not very frequent, it should be considered as differential diagnosis in those clinical cases that are accompanied with important general commitment, linphadenopaties and respons to steroid therapy.

  19. Blood and Lymph Diseases

    Science.gov (United States)

    ... and Disease [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 1998-. Blood and Lymph Diseases. PDF version of this page ( ... On Blood and Lymph Diseases - Genes and Disease Blood and Lymph Diseases - Genes and Disease Your browsing ... Biotechnology Information , U.S. National Library of Medicine 8600 Rockville ...

  20. Muscle disease.

    Science.gov (United States)

    Tsao, Chang-Yong

    2014-02-01

    On the basis of strong research evidence, Duchenne muscular dystrophy (DMD), the most common severe childhood form of muscular dystrophy, is an X-linked recessive disorder caused by out-of-frame mutations of the dystrophin gene. Thus, it is classified asa dystrophinopathy. The disease onset is before age 5 years. Patients with DMD present with progressive symmetrical limb-girdle muscle weakness and become wheelchair dependent after age 12 years. (2)(3). On the basis of some research evidence,cardiomyopathy and congestive heart failure are usually seen in the late teens in patients with DMD. Progressive scoliosis and respiratory in sufficiency often develop once wheelchair dependency occurs. Respiratory failure and cardiomyopathy are common causes of death, and few survive beyond the third decade of life. (2)(3)(4)(5)(6)(7). On the basis of some research evidence, prednisone at 0.75 mg/kg daily (maximum dose, 40 mg/d) or deflazacort at 0.9 mg/kg daily (maximum dose, 39 mg/d), a derivative of prednisolone (not available in the United States), as a single morning dose is recommended for DMD patients older than 5 years, which may prolong independent walking from a few months to 2 years. (2)(3)(16)(17). Based on some research evidence, treatment with angiotensin-converting enzyme inhibitors, b-blockers, and diuretics has been reported to be beneficial in DMD patients with cardiac abnormalities. (2)(3)(5)(18). Based on expert opinion, children with muscle weakness and increased serum creatine kinase levels may be associated with either genetic or acquired muscle disorders (Tables 1 and 3). (14)(15)

  1. Alzheimer disease: An interactome of many diseases

    Directory of Open Access Journals (Sweden)

    Balaji S Rao

    2014-01-01

    Full Text Available Alzheimer Disease (AD is an outcome as well as source of many diseases. Alzheimer is linked with many other diseases like Diabetes type 2, cholesterolemia, hypertension and many more. But how each of these diseases affecting other is still unknown to scientific community. Signaling Pathways of one disease is interlinked with other disease. But to what extent healthy brain is affected when any signaling in human body is disturbed is the question that matters. There is a need of Pathway analysis, Protein-Protein interaction (PPI and the conserved interactome study in AD and linked diseases. It will be helpful in finding the potent drug or vaccine target in conscious manner. In the present research the Protein-Protein interaction of all the proteins involved in Alzheimer Disease is analyzed using ViSANT and osprey tools and pathway analysis further reveals the significant genes/proteins linking AD with other diseases.

  2. Association between periodontal diseases and systemic diseases.

    Science.gov (United States)

    Weidlich, Patrícia; Cimões, Renata; Pannuti, Claudio Mendes; Oppermann, Rui Vicente

    2008-01-01

    Current evidence suggests that periodontal disease may be associated with systemic diseases. This paper reviewed the published data about the relationship between periodontal disease and cardiovascular diseases, adverse pregnancy outcomes, diabetes and respiratory diseases, focusing on studies conducted in the Brazilian population. Only a few studies were found in the literature focusing on Brazilians (3 concerning cardiovascular disease, 7 about pregnancy outcomes, 9 about diabetes and one regarding pneumonia). Although the majority of them observed an association between periodontitis and systemic conditions, a causal relationship still needs to be demonstrated. Further studies, particularly interventional well-designed investigations, with larger sample sizes, need to be conducted in Brazilian populations.

  3. Inflammatory bowel disease and airway diseases

    Science.gov (United States)

    Vutcovici, Maria; Brassard, Paul; Bitton, Alain

    2016-01-01

    Airway diseases are the most commonly described lung manifestations of inflammatory bowel disease (IBD). However, the similarities in disease pathogenesis and the sharing of important environmental risk factors and genetic susceptibility suggest that there is a complex interplay between IBD and airway diseases. Recent evidence of IBD occurrence among patients with airway diseases and the higher than estimated prevalence of subclinical airway injuries among IBD patients support the hypothesis of a two-way association. Future research efforts should be directed toward further exploration of this association, as airway diseases are highly prevalent conditions with a substantial public health impact. PMID:27678355

  4. Association between periodontal diseases and systemic diseases

    Directory of Open Access Journals (Sweden)

    Patrícia Weidlich

    2008-08-01

    Full Text Available Current evidence suggests that periodontal disease may be associated with systemic diseases. This paper reviewed the published data about the relationship between periodontal disease and cardiovascular diseases, adverse pregnancy outcomes, diabetes and respiratory diseases, focusing on studies conducted in the Brazilian population. Only a few studies were found in the literature focusing on Brazilians (3 concerning cardiovascular disease, 7 about pregnancy outcomes, 9 about diabetes and one regarding pneumonia. Although the majority of them observed an association between periodontitis and systemic conditions, a causal relationship still needs to be demonstrated. Further studies, particularly interventional well-designed investigations, with larger sample sizes, need to be conducted in Brazilian populations.

  5. Skin Diseases: Skin Health and Skin Diseases

    Science.gov (United States)

    Skip Navigation Bar Home Current Issue Past Issues Skin Diseases Skin Health and Skin Diseases Past Issues / Fall 2008 Table of Contents ... acne to wrinkles Did you know that your skin is the largest organ of your body? It ...

  6. Acquired Cystic Kidney Disease

    Science.gov (United States)

    ... Kidney Disease (CKD) What Is Chronic Kidney Disease? Causes of CKD Tests & Diagnosis Managing CKD Eating Right Preventing CKD ... as polycystic kidney disease (PKD), another disease that causes the kidneys to ... chronic kidney disease (CKD)—a condition that develops over many years ...

  7. Lyme Disease (For Parents)

    Science.gov (United States)

    ... Teaching Kids to Be Smart About Social Media Lyme Disease KidsHealth > For Parents > Lyme Disease Print A A ... en español La enfermedad de Lyme What Is Lyme Disease? Lyme disease is the leading tick-borne disease ...

  8. Virus diseases of fish

    Science.gov (United States)

    Watson, Stanley W.

    1954-01-01

    Viruses are probably the cause of a wide spectrum of fish diseases. Although relatively few virus diseases of fish are known today, some of the diseases of unknown etiology, as well as some diseases presently accepted as due to bacteria, protozoa, fungi or nutritional deficiencies, possibly will be recognized eventually as virus diseases.

  9. KEGG DISEASE / Acute encephalitis [KEGG DISEASE

    Lifescience Database Archive (English)

    Full Text Available DISEASE: H01417 Entry H01417Disease Name Acute encephalitis Description Acute encep...ns Infections caused by dsDNA viruses H01417Acute encephalitis Human diseases in ICD-10 classification [BR:b...of the central nervous system G04Encephalitis, myelitis and encephalomyelitis H01417Acute encephalitis Patho...elines for management. Journal Eur J Neurol 12:331-43 (2005) KEGG DISEASE / Acute encephalitis ...

  10. Coronary Artery Disease - Coronary Heart Disease

    Science.gov (United States)

    ... result of coronary artery disease, or CAD, said Edward A. Fisher, M.D., Ph.D., M.P. ... Problems and Disease • High Blood Pressure (HBP) • Metabolic Syndrome • Pericarditis • Peripheral Artery Disease (PAD) • Stroke • Vascular Health • ...

  11. KEGG DISEASE / Acute alcohol sensitivity [KEGG DISEASE

    Lifescience Database Archive (English)

    Full Text Available DISEASE: H01071 Entry H01071Disease Name Acute alcohol sensitivity Description Alde...bolism Congenital disorders of carbohydrate metabolism H01071Acute alcohol sensit...eases. Journal Cardiovasc Res 88:51-7 (2010) KEGG DISEASE / Acute alcohol sensitivity ...

  12. Lysosomal storage disease 2 - Pompe's disease

    NARCIS (Netherlands)

    van der Ploeg, Ans T.; Reuser, Arnold J. J.

    2008-01-01

    Pompe's disease, glycogen-storage disease type II, and acid maltase deficiency are alternative names for the same metabolic disorder. It is a pan-ethnic autosomal recessive trait characterised by acid alpha-glucosidase deficiency leading to lysosomal glycogen storage. Pompe's disease is also

  13. Anemia of chronic disease

    Science.gov (United States)

    ... disease Long-term infections, such as bacterial endocarditis, osteomyelitis (bone infection), HIV/AIDS , hepatitis B or hepatitis ... disease Crohn disease Erythropoietin test Juvenile idiopathic arthritis Osteomyelitis Rheumatic fever Ulcerative colitis Review Date 2/1/ ...

  14. Parkinson's Disease Videos

    Medline Plus

    Full Text Available ... Parkinson's Disease Cognition: A Mind Guide to Parkinson’s Disease Nutrition Matters Speech and Swallowing Psychosis: A Mind Guide to Parkinson's Disease Guide to Deep Brain Stimulation You Can Make ...

  15. Parkinson's Disease Videos

    Medline Plus

    Full Text Available ... and Social Network? How Does Parkinson's Disease Affect Memory? How Does Parkinson's Disease Affect the Urinary System? ... Parkinson's Disease Patients with a Depression Diagnosis? What Type of Exercise or Exercise Programs Are Recommended? What ...

  16. Newcastle Disease Virus (PDQ)

    Science.gov (United States)

    ... Professionals Questions to Ask about Your Treatment Research Newcastle Disease Virus (PDQ®)–Patient Version Overview Go to ... cancer (see Question 8 ). Questions and Answers About Newcastle Disease Virus What is Newcastle disease virus? Newcastle ...

  17. Learn About Neuromuscular Disease

    Science.gov (United States)

    ... Inherited and Endocrine Myopathies Metabolic Diseases of Muscle Mitochondrial Myopathies (MM) Myotonic Muscular Dystrophy (MMD) Spinal-Bulbar Muscular ... Deficient Congenital Muscular Dystrophy Metabolic Diseases of Muscle Mitochondrial Myopathy Miyoshi Distal Myopathy Motor Neurone Disease Muscle-Eye- ...

  18. Autoimmune liver disease panel

    Science.gov (United States)

    Liver disease test panel - autoimmune ... Autoimmune disorders are a possible cause of liver disease. The most common of these diseases are autoimmune hepatitis and primary biliary cholangitis (formerly called primary biliary cirrhosis). This group of tests ...

  19. Liver Disease and IBD

    Science.gov (United States)

    ... Home > Resources > Liver Disease and IBD Go Back Liver Disease and IBD Email Print + Share Several complications ... be necessary to make the definitive diagnosis. FATTY LIVER DISEASE (HEPATCI STEATOSIS) This is the most common ...

  20. Leprosy (Hansen's Disease)

    Science.gov (United States)

    ... with facebook share with twitter share with linkedin Leprosy (Hansen's Disease) Leprosy (Hansen's Disease) is a chronic ... as Mycobacterium leprae . Why Is the Study of Leprosy (Hansen's Disease) a Priority for NIAID? At the ...