Detecting nuclear warheads

International Nuclear Information System (INIS)

Fetter, S.; Frolov, V.A.; Prilutsky, O.F.; Rodionov, S.N.; Sagdeev, R.Z.; Miller, M.

1992-01-01

To the best of our knowledge, all nuclear weapons contain at least several kilograms of fissile material - material that can sustain a chain reaction. Such material provides the energy for fission explosives such as those that destroyed Hiroshima and Nagasaki; it is also used in the fission trigger modern thermonuclear weapons. The two fissile materials used in US and Soviet warheads are weapon grade uranium (WgU) and weapon-grade plutonium (WgPu). Fissile materials are radioactive; they are very dense and absorb certain radiations very well; and they can be fissioned. This paper reports on the two basic ways to detect fissile material: passive detection of the radiation emitted by its radioactive decay, or active detection involving either radiographing (x-raying) an object with neutrons or high-energy photons and detecting particles emitted by the resulting induced fissions. Passive detection is the preferred technique for verification purposes because of its simplicity and safety

The Stockpile Monitor Program

International Nuclear Information System (INIS)

Buntain, G.A.; Fletcher, M.; Rabie, R.

1994-07-01

Recent political changes have led to drastic reductions in the number of nuclear warheads in stockpile, as well as increased expectations for warhead-service lives. In order to support and maintain a shrinking and aging nuclear stockpile, weapon scientists and engineers need detailed information describing the environments experienced by weapons in the field. Hence, the Stockpile Monitor Program was initiated in 1991 to develop a comprehensive and accurate database of temperature and humidity conditions experienced by nuclear warheads both in storage and on-alert

Transforming Normal Programs by Replacement

NARCIS (Netherlands)

Bossi, Annalisa; Pettorossi, A.; Cocco, Nicoletta; Etalle, Sandro

1992-01-01

The replacement transformation operation, already defined in [28], is studied wrt normal programs. We give applicability conditions able to ensure the correctness of the operation wrt Fitting's and Kunen's semantics. We show how replacement can mimic other transformation operations such as thinning,

Applying the neutron scatter camera to treaty verification and warhead monitoring

International Nuclear Information System (INIS)

Cooper, Robert Lee; Gerling, Mark; Brennan, James S.; Mascarenhas, Nicholas; Mrowka, Stanley; Marleau, Peter

2010-01-01

The neutron scatter camera was originally developed for a range of SNM detection applications. We are now exploring the feasibility of applications in treaty verification and warhead monitoring using experimentation, maximum likelihood estimation method (MLEM), detector optimization, and MCNP-PoliMi simulations.

Refrigerator retirement and replacement programs : lessons learned and application to an Ontario wide program

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-05-15

The best practices in refrigerator retirement programs in North America were identified in an effort to develop a concept for an Ontario-wide provincial refrigerator retirement program. The report focused on describing refrigerator retirement programs, namely those programs that focused on getting rid of old secondary refrigerators. The report excluded refrigerator replacement programs, which encourage householders to retire their refrigerators early and replace them with an energy star refrigerator. However, it was noted that in several regions, both replacement and retirement programs are offered at the same time. The report provided background information on energy use by refrigerators as well as refrigerator retirement and replacement programs. Types of refrigerator retirement and replacement programs and the environmental benefits of these programs were also described. The report also addressed the potential energy impact of an Ontario-wide refrigerator retirement program as well as consumer incentive and bounties initiatives to encourage households to retire units. Other topics covered in the report included the design of typical refrigerator retirement and replacement programs; collection and recycling of retired refrigerators; reported costs of refrigerator retirement and replacement programs; as well as marketing and advertising. The role of retailers and manufacturers and reported lessons learned from refrigerator retirement and replacement were also presented. 14 refs., 6 tabs., 6 appendices.

Increasing transparency of nuclear-warhead and fissile-material stocks as a step toward disarmament -- Proposals for the NPT PrepCom, Geneva

International Nuclear Information System (INIS)

2013-04-01

These proposals made by the International Panel on Fissile Materials IPFM at a conference in Geneva, Switzerland, in April 2013 discuss how increasing transparency can help disarmament efforts. After a short introduction to IPFM and its mission, the action plan on nuclear disarmament is looked at and the various nations involved are listed. A set of baseline declarations proposed are discussed. These include warhead stocks, potential new declarations and fissile material stocks. Monitoring by the International Atomic Energy Authority IAEA is also reviewed. Preparations for future declarations concerning warhead and delivery systems locations, stockpile histories and fissile material production and disposal aspects are reported on. Finally, co-operative verification projects, warhead dismantlement and past fissile material production are examined

Nuclear Weapons Enterprise Transformation - A Sustainable Approach

International Nuclear Information System (INIS)

O'Brien, K H

2005-01-01

with an improved vision of the future stockpile and enterprise, and find a path that moves us toward that future. The goal of this approach is to achieve a more affordable, sustainable, and responsive enterprise. In order to transform the enterprise in this way, the SSP warhead designs that drive the enterprise must change. Designs that emphasize manufacturability, certifiability, and increased safety and security can enable enterprise transformation. It is anticipated that such warheads can be certified and sustained with high confidence without nuclear testing. The SSP provides the tools to provide such designs, and can develop replacement designs and produce them for the stockpile. The Cold War currency of optimizing warhead yield-to-weight can be replaced by SSP designs optimizing margin-to-uncertainty. The immediate challenge facing the nuclear weapons enterprise is to find a credible path that leads to this vision of the future stockpile and enterprise. Reliable warheads within a sustainable enterprise can best be achieved by shifting from a program of legacy-warhead refurbishment to one of warhead replacement. The nuclear weapons stockpile and the nuclear weapons enterprise must transform together to achieve this vision. The current Reliable Replacement Warhead (RRW) program represents an approach that can begin this process of transformation. If the RRW program succeeds, the designs, manufacturing complex, and certification strategy can evolve together and in so doing come up with a more cost-efficient solution that meets today's and tomorrow's national security requirements

A New Approach to Nuclear Warhead Verification Using a Zero-Knowledge Protocol

Energy Technology Data Exchange (ETDEWEB)

Glaser,; Alexander, [Princeton University

2012-05-16

Warhead verification systems proposed to date fundamentally rely on the use of information barriers to prevent the release of classified design information. Measurements with information carriers significantly increase the complexity of inspection systems, make their certification and authentication difficult, and may reduce the overall confidence in the verifiability of future arms- control agreements. This talk presents a proof-of-concept of a new approach to nuclear warhead verification that minimizes the role of information barriers from the outset and envisions instead an inspection system that a priori avoids leakage of sensitive information using a so-called zero-knowledge protocol. The proposed inspection system is based on the template-matching approach and relies on active interrogation of a test object with 14-MeV neutrons. The viability of the method is examined with MCNP Monte Carlo neutron transport calculations modeling the experimental setup, an investigation of different diversion scenarios, and an analysis of the simulated data showing that it does not contain information about the properties of the inspected object.

A treaty more alarming than efficient. The dismantled warheads will not be destroyed. Danger

International Nuclear Information System (INIS)

Riche, P.; Despic-Popovic, H.; Nougayrede, N.

2002-01-01

This political analysis presents the new treaty of nuclear weapons dismantling between Russia and Usa. In fact the warheads will not be completely dismantling but only stocked, leading to a possible recovery by terrorists. It underlines the real interests of this agreement which are more economic than peaceful. (A.L.B.)

A new method of passive counting of nuclear missile warheads -a white paper for the Defense Threat Reduction Agency

Energy Technology Data Exchange (ETDEWEB)

Morris, Christopher [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Durham, J. Matthew [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Guardincerri, Elena [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Bacon, Jeffrey Darnell [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Wang, Zhehui [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Fellows, Shelby [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Poulson, Daniel Cris [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Plaud-Ramos, Kenie Omar [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Daughton, Tess Marie [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Johnson, Olivia Ruth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2015-07-31

Cosmic ray muon imaging has been studied for the past several years as a possible technique for nuclear warhead inspection and verification as part of the New Strategic Arms Reduction Treaty between the United States and the Russian Federation. The Los Alamos team has studied two different muon imaging methods for this application, using detectors on two sides and one side of the object of interest. In this report we present results obtained on single sided imaging of configurations aimed at demonstrating the potential of this technique for counting nuclear warheads in place with detectors above the closed hatch of a ballistic missile submarine.

Securing nuclear warheads and materials: seven steps for immediate action

International Nuclear Information System (INIS)

Bunn, M.

2002-01-01

Full text: In the last decade, substantial progress has been made in improving security and accounting for nuclear weapons and weapons-usable nuclear material worldwide, both by states' own domestic actions and through international cooperation. Thousands of nuclear warheads and hundreds of tons of nuclear material are demonstrably more secure than they were before, and through programs such as the U.S.-Russian Highly Enriched Uranium (He) Purchase Agreement, enough potentially vulnerable bomb material for thousands of nuclear weapons has been verifiably destroyed. Since the attacks of September 11, 2001, the international community has attempted to expand and accelerate these efforts. But much more remains to be done. This paper summarizes a recent report from Harvard University, which recommended seven further steps for immediate action in U.S.-Russian and international cooperation. It covers two recommendations that may be of particular interest to this audience in detail. The first is a proposed program to remove nuclear material entirely from many of the most vulnerable sites around the world (by offering incentives targeted to the needs of each facility to give up the material at that site). The second is a suggestion that participants in the global partnership against the spread of weapons and materials of mass destruction announced at the June 2002 Group of Eight summit make a political commitment to meet stringent security standards for nuclear materials on their territories, and urge (and assist) other states to do likewise. (author)

Optimal timing of joint replacement using mathematical programming and stochastic programming models.

Science.gov (United States)

Keren, Baruch; Pliskin, Joseph S

2011-12-01

The optimal timing for performing radical medical procedures as joint (e.g., hip) replacement must be seriously considered. In this paper we show that under deterministic assumptions the optimal timing for joint replacement is a solution of a mathematical programming problem, and under stochastic assumptions the optimal timing can be formulated as a stochastic programming problem. We formulate deterministic and stochastic models that can serve as decision support tools. The results show that the benefit from joint replacement surgery is heavily dependent on timing. Moreover, for a special case where the patient's remaining life is normally distributed along with a normally distributed survival of the new joint, the expected benefit function from surgery is completely solved. This enables practitioners to draw the expected benefit graph, to find the optimal timing, to evaluate the benefit for each patient, to set priorities among patients and to decide if joint replacement should be performed and when.

The Replacement Operation for CCP Programs

NARCIS (Netherlands)

Bertolino, Marco; Etalle, Sandro; Palamidessi, Catuscia

1999-01-01

The Replacement is a very powerful transformation operation which - both within the functional paradigm as well as within the logic programming one - can micic the most common transformation operations such as unfold, fold, switching, distribution. Because of this flexibility , it can be incorrect

The Replacement Operation for CCP Programs

NARCIS (Netherlands)

Bertolino, Marco; Bossi, Annalisa; Etalle, Sandro; Palamidessi, Catuscia

2000-01-01

The Replacement is a very powerful transformation operation which - both within the functional paradigm as well as within the logic programming one - can micic the most common transformation operations such as unfold, fold, switching, distribution. Because of this flexibility , it can be incorrect

Disposition of plutonium from dismantled warheads: Belgonucleaire's proposal

International Nuclear Information System (INIS)

Haas, D.; Vanderborck, Y.; Vandenberg, C.; Vliet, J. van

1996-01-01

Set up in 1957 by Union Miniere, Belgonucleaire (BN) has been working since its origin in the field of plutonium and has accumulated extensive experience in the design and fabrication of mixed-oxide (MOX) fuel, as well as in the fuel management and licensing of MOX cores for fast breeder reactors (FBRs), pressurized water reactors (PWRs), and boiling water reactors (BWRs). Although BN's MOX plant first went into operation in 1973 (it was used for FBRs and light water reactor (LWR) demonstration fuel fabrication), industrial production started in 1986. The MOX fuel produced (280 t heavy metal (HM) until the end of 1995) has been loaded in PWRs and BWRs in four countries in Europe: France, Germany, Switzerland, and Belgium. They propose the development of MOX plants as the means for disposal of plutonium from warhead disassembly

Investigation of the protection possibilities against enhanced radiation warhead

International Nuclear Information System (INIS)

Sahin, S.; Erisen, A.; Selvi, S.; Yalcin, S.

1980-01-01

To evaluate an enhanced radiation protection for the tank crew against the neutron bomb, we first have analysed the propagation of the 14.1 MeV neutron in air in S 8 approximation. Three new tank wall proposals for enhanced radiation protection have been discussed in S 4 approximation. The best protection for the tank crew against the neutron bomb radiation has been achieved by covering the internal tank wall with a borated polyethylene layer. However the radiation damage through the neutron bomb cannot be degradated to the radiation damage level by a standard nuclear warhead of comparable energy release. In the course of this study a 27 group hard spectra data library has been used. (orig.) 891 HP/orig. 892 CKA [de

75 FR 80536 - Notice Pursuant to the National Cooperative Research and Production Act of 1993 National Warheads...

Science.gov (United States)

2010-12-22

... Production Act of 1993 National Warheads and Energetics Consortium Notice is hereby given that, on November 30, 2010, pursuant to Section 6(a) of the National Cooperative Research and Production Act of 1993... Mountain Scientific Laboratory, Centennial, CO; Rocky Research, Boulder City, NV; The Research Foundation...

Continuous quality improvement program for hip and knee replacement.

Science.gov (United States)

Marshall, Deborah A; Christiansen, Tanya; Smith, Christopher; Squire Howden, Jane; Werle, Jason; Faris, Peter; Frank, Cy

2015-01-01

Improving quality of care and maximizing efficiency are priorities in hip and knee replacement, where surgical demand and costs increase as the population ages. The authors describe the integrated structure and processes from the Continuous Quality Improvement (CQI) Program for Hip and Knee Replacement Surgical Care and summarize lessons learned from implementation. The Triple Aim framework and 6 dimensions of quality care are overarching constructs of the CQI program. A validated, evidence-based clinical pathway that measures quality across the continuum of care was adopted. Working collaboratively, multidisciplinary experts embedded the CQI program into everyday practices in clinics across Alberta. Currently, 83% of surgeons participate in the CQI program, representing 95% of the total volume of hip and knee surgeries. Biannual reports provide feedback to improve care processes, infrastructure planning, and patient outcomes. CQI programs evaluating health care services inform choices to optimize care and improve efficiencies through continuous knowledge translation. © The Author(s) 2014.

Shielding requirements for the transport of nuclear warhead components under decommissioning

International Nuclear Information System (INIS)

Hansen, L.F.

1994-09-01

The requirements to carry out accurate shielding calculations involved with the safe off-site transportation of packages containing nuclear warhead components, special assemblies and radioactive materials are discussed. The need for (a) detailed information on the geometry and material composition of the packaging and radioactive load, (b) accurate representation of the differential energy spectra (dN/dE) for the neutron and gamma spectra emitted by the radioactive materials enclosed in the packaging, (c) well-tested neutron and photon cross section libraries, (d) and accurate three-dimensional Monte Carlo transport codes are illustrated. A brief discussion of the need for reliable dose measurements is presented

Navy Ohio Replacement (SSBN[X]) Ballistic Missile Submarine Program: Background and Issues for Congress

Science.gov (United States)

2016-04-05

Navy Ohio Replacement (SSBN[X]) Ballistic Missile Submarine Program: Background and Issues for Congress Ronald O’Rourke Specialist in Naval...Affairs April 5, 2016 Congressional Research Service 7-5700 www.crs.gov R41129 Navy Ohio Replacement (SSBN[X]) Ballistic Missile Submarine...1,091.1 million in research and development funding for the Ohio replacement program (ORP), a program to design and build a new class of 12 ballistic

An optimal maintenance policy for machine replacement problem using dynamic programming

OpenAIRE

Mohsen Sadegh Amalnik; Morteza Pourgharibshahi

2017-01-01

In this article, we present an acceptance sampling plan for machine replacement problem based on the backward dynamic programming model. Discount dynamic programming is used to solve a two-state machine replacement problem. We plan to design a model for maintenance by consid-ering the quality of the item produced. The purpose of the proposed model is to determine the optimal threshold policy for maintenance in a finite time horizon. We create a decision tree based on a sequential sampling inc...

Low-Intrusion Techniques and Sensitive Information Management for Warhead Counting and Verification: FY2011 Annual Report

Energy Technology Data Exchange (ETDEWEB)

Jarman, Kenneth D.; Robinson, Sean M.; McDonald, Benjamin S.; Gilbert, Andrew J.; Misner, Alex C.; Pitts, W. Karl; White, Timothy A.; Seifert, Allen; Miller, Erin A.

2011-09-01

Future arms control treaties may push nuclear weapons limits to unprecedented low levels and may entail precise counting of warheads as well as distinguishing between strategic and tactical nuclear weapons. Such advances will require assessment of form and function to confidently verify the presence or absence of nuclear warheads and/or their components. Imaging with penetrating radiation can provide such an assessment and could thus play a unique role in inspection scenarios. Yet many imaging capabilities have been viewed as too intrusive from the perspective of revealing weapon design details, and the potential for the release of sensitive information poses challenges in verification settings. A widely held perception is that verification through radiography requires images of sufficient quality that an expert (e.g., a trained inspector or an image-matching algorithm) can verify the presence or absence of components of a device. The concept of information barriers (IBs) has been established to prevent access to relevant weapon-design information by inspectors (or algorithms), and has, to date, limited the usefulness of radiographic inspection. The challenge of this project is to demonstrate that radiographic information can be used behind an IB to improve the capabilities of treaty-verification weapons-inspection systems.

Replacement model of city bus: A dynamic programming approach

Science.gov (United States)

Arifin, Dadang; Yusuf, Edhi

2017-06-01

This paper aims to develop a replacement model of city bus vehicles operated in Bandung City. This study is driven from real cases encountered by the Damri Company in the efforts to improve services to the public. The replacement model propounds two policy alternatives: First, to maintain or keep the vehicles, and second is to replace them with new ones taking into account operating costs, revenue, salvage value, and acquisition cost of a new vehicle. A deterministic dynamic programming approach is used to solve the model. The optimization process was heuristically executed using empirical data of Perum Damri. The output of the model is to determine the replacement schedule and the best policy if the vehicle has passed the economic life. Based on the results, the technical life of the bus is approximately 20 years old, while the economic life is an average of 9 (nine) years. It means that after the bus is operated for 9 (nine) years, managers should consider the policy of rejuvenation.

Transportation of nuclear weapons through urban areas in the United Kingdom

International Nuclear Information System (INIS)

1990-01-01

This study concentrates on the road carriage of assembled nuclear warheads to and from the Royal Ordnance factory at Burghfield, Berkshire - a task that is necessary to deliver new warheads to the sites of storage and deployment, and which also entails movement of existing stocks of warheads being returned to Burghfield for maintenance, refurbishing and or replacement. During these movements there is risk of accident and damage to the warhead assemblies in transit and, therefore, consequences that could result in harm to people and property in the locality of the accident. (author)

Authentication concept and impact of pit containers on neutron analysis

Energy Technology Data Exchange (ETDEWEB)

Goettsche, Malte [Centre for Science and Peace Research, University of Hamburg (Germany)

2013-07-01

One part of verifying the dismantlement of nuclear warheads will very likely be the authentication of warheads where their authenticities would be confirmed via radiation measurements. Such authentication would be more achievable if dismantled warhead components were verified as opposed to the entire warhead due to unknown shielding in the warhead that would be replaced in the case of components by shielding of a container where the design might be known. Such a procedure would require a robust chain-of-custody, where confidence would be created that the dismantled warhead components correspond to the former warhead in terms of integrity and identity. The argument is sometimes made though that the containers where the components would be stored act as a strong shielding that might prevent authentication measurements. In this presentation, plausible container configurations are considered and analyzed in regard to measurability of neutron multiplicities using Helium-3 detectors. Such a measurement would allow the determination of fissile mass which is considered one attribute for authenticating warheads.

Experience with Designing and Implementing a Bundled Payment Program for Total Hip Replacement.

Science.gov (United States)

Whitcomb, Winthrop F; Lagu, Tara; Krushell, Robert J; Lehman, Andrew P; Greenbaum, Jordan; McGirr, Joan; Pekow, Penelope S; Calcasola, Stephanie; Benjamin, Evan; Mayforth, Janice; Lindenauer, Peter K

2015-09-01

Bundled payments, also known as episode-based payments, are intended to contain health care costs and promote quality. In 2011 a bundled payment pilot program for total hip replacement was implemented by an integrated health care delivery system in conjunction with a commercial health plan subsidiary. In July 2015 the Centers for Medicare & Medicaid Services (CMS) proposed the Comprehensive Care for Joint Replacement Model to test bundled payment for hip and knee replacement. Stakeholders were identified and a structure for program development and implementation was created. An Oversight Committee provided governance over a Clinical Model Subgroup and a Financial Model Subgroup. The pilot program included (1) a clinical model of care encompassing the period from the preoperative evaluation through the third postoperative visit, (2) a pricing model, (3) a program to share savings, and (4) a patient engagement and expectation strategy. Compared to 32 historical controls-patients treated before bundle implementation-45 post-bundle-implementation patients with total hip replacement had a similar length of hospital stay (3.0 versus 3.4 days, p=.24), higher rates of discharge to home or home with services than to a rehabilitation facility (87% versus 63%), similar adjusted median total payments ($22,272 versus $22,567, p=.43), and lower median posthospital payments ($704 versus $1,121, p=.002), and were more likely to receive guideline-consistent care (99% versus 95%, p=.05). The bundled payment pilot program was associated with similar total costs, decreased posthospital costs, fewer discharges to rehabilitation facilities, and improved quality. Successful implementation of the program hinged on buy-in from stakeholders and close collaboration between stakeholders and the clinical and financial teams.

An optimal maintenance policy for machine replacement problem using dynamic programming

Directory of Open Access Journals (Sweden)

Mohsen Sadegh Amalnik

2017-06-01

Full Text Available In this article, we present an acceptance sampling plan for machine replacement problem based on the backward dynamic programming model. Discount dynamic programming is used to solve a two-state machine replacement problem. We plan to design a model for maintenance by consid-ering the quality of the item produced. The purpose of the proposed model is to determine the optimal threshold policy for maintenance in a finite time horizon. We create a decision tree based on a sequential sampling including renew, repair and do nothing and wish to achieve an optimal threshold for making decisions including renew, repair and continue the production in order to minimize the expected cost. Results show that the optimal policy is sensitive to the data, for the probability of defective machines and parameters defined in the model. This can be clearly demonstrated by a sensitivity analysis technique.

AUTOMR: An automatic processing program system for the molecular replacement method

International Nuclear Information System (INIS)

Matsuura, Yoshiki

1991-01-01

An automatic processing program system of the molecular replacement method AUTMR is presented. The program solves the initial model of the target crystal structure using a homologous molecule as the search model. It processes the structure-factor calculation of the model molecule, the rotation function, the translation function and the rigid-group refinement successively in one computer job. Test calculations were performed for six protein crystals and the structures were solved in all of these cases. (orig.)

The use of helicopter-borne neutron detectors to detect nuclear warheads in the USSR-US Black Sea experiment

International Nuclear Information System (INIS)

Belyaev, S.T.; Lebedev, V.I.; Obinyakov, B.A.; Zemlyakov, M.V.; Ryazantsev, V.A.; Armashov, V.M.

1992-01-01

This paper reports that the Soviet Navy used a helicopter/ship system called Sovietnik to detect a cruise-missile warhead in the joint USSR-US experiment on the Black Sea, which took place on 5 July 1989. The system consists of a ship-based helicopter, equipped with a neutron detector and processing equipment, associated ship-based equipment. The neutron detector, together with instrumentation for recording preliminary processing, and analysis of initial information, is located on the helicopter, which carries out the measurement while flying slowly past the ship in question

A Water Rehabilitation Program in Patients with Hip Osteoarthritis Before and After Total Hip Replacement.

Science.gov (United States)

Łyp, Marek; Kaczor, Ryszard; Cabak, Anna; Tederko, Piotr; Włostowska, Ewa; Stanisławska, Iwona; Szypuła, Jan; Tomaszewski, Wiesław

2016-07-25

BACKGROUND Pain associated with coxarthrosis, typically occurring in middle-aged and elderly patients, very commonly causes considerable limitation of motor fitness and dependence on pharmacotherapy. This article provides an assessment of a rehabilitation program with tailored water exercises in patients with osteoarthritis before and after total hip replacement. MATERIAL AND METHODS A total of 192 patients (the mean age 61.03±10.89) suffering from hip osteoarthritis (OA) were evaluated before and after total hip replacement (THR). The clinical study covered measurements of hip active ranges of motion (HAROM) and the forces generated by pelvis stabilizer muscles. Pain intensity was assessed according to analogue-visual scale of pain (VAS) and according to the Modified Laitinen Questionnaire. The patients were divided into 6 groups (4 treatment and 2 control). We compared 2 rehabilitation programs using kinesitherapy and low-frequency magnetic field. One of them also had specially designed exercises in the water. Statistical analysis was carried out at the significance level α=0.05. This was a cross-sectional study. RESULTS A positive effect of water exercises on a number of parameters was found in patients with OA both before and after total hip replacement surgery. We noted a significant reduction of pain (pwater exercises most significantly reduced pain in patients with OA before and after total hip replacement surgery. 2. Inclusion of water exercises in a rehabilitation program can reduce the use of medicines in patient with OA and after THR.

24 CFR 572.125 - Replacement reserves.

Science.gov (United States)

2010-04-01

...) Homeownership Program Requirements-Implementation Grants § 572.125 Replacement reserves. (a) Purpose. A single replacement reserve may be established for the homeownership program only if HUD determines it is necessary to... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Replacement reserves. 572.125...

REDUCTIONS WITHOUT REGRET: DEFINING THE NEEDED CAPABILITIES

Energy Technology Data Exchange (ETDEWEB)

Swegle, J.; Tincher, D.

2013-09-10

This is the second of three papers (in addition to an introductory summary) aimed at providing a framework for evaluating future reductions or modifications of the U.S. nuclear force, first by considering previous instances in which nuclear-force capabilities were eliminated; second by looking forward into at least the foreseeable future at the features of global and regional deterrence (recognizing that new weapon systems currently projected will have expected lifetimes stretching beyond our ability to predict the future); and third by providing examples of past or possible undesirable outcomes in the shaping of the future nuclear force, as well as some closing thoughts for the future. This paper begins with a discussion of the current nuclear force and the plans and procurement programs for the modernization of that force. Current weapon systems and warheads were conceived and built decades ago, and procurement programs have begun for the modernization or replacement of major elements of the nuclear force: the heavy bomber, the air-launched cruise missile, the ICBMs, and the ballistic-missile submarines. In addition, the Nuclear Weapons Council has approved a new framework for nuclear-warhead life extension not fully fleshed out yet that aims to reduce the current number of nuclear explosives from seven to five, the so-called 3+2 vision. This vision includes three interoperable warheads for both ICBMs and SLBMs (thus eliminating one backup weapon) and two warheads for aircraft delivery (one gravity bomb and one cruise-missile, eliminating a second backup gravity bomb). This paper also includes a discussion of the current and near-term nuclear-deterrence mission, both global and regional, and offers some observations on future of the strategic deterrence mission and the challenges of regional and extended nuclear deterrence.

A treaty more alarming than efficient. The dismantled warheads will not be destroyed. Danger; Un traite plus inquietant qu'efficace. Les ogives demantelees ne seront pas detruites. Risque

Energy Technology Data Exchange (ETDEWEB)

Riche, P.; Despic-Popovic, H.; Nougayrede, N

2002-07-01

This political analysis presents the new treaty of nuclear weapons dismantling between Russia and Usa. In fact the warheads will not be completely dismantling but only stocked, leading to a possible recovery by terrorists. It underlines the real interests of this agreement which are more economic than peaceful. (A.L.B.)

Improving maintenance of lost weight following a commercial liquid meal replacement program: a preliminary study.

Science.gov (United States)

Ames, Gretchen E; Patel, Roshni H; McMullen, Jillian S; Thomas, Colleen S; Crook, Julia E; Lynch, Scott A; Lutes, Lesley D

2014-01-01

Clinic-based liquid meal replacement (800kcals/day) programs produce substantial weight loss. Nevertheless, long-term maintenance remains a challenge. A limitation of maintenance programs is that they continue to promote large behavior changes that are initially required to induce weight loss which may be unsustainable long-term. The study aims were to conduct a preliminary assessment of the feasibility, acceptability, and effectiveness of a small changes maintenance intervention (SCM) for 30 patients who completed liquid meal replacement program (LMR). The 20-session SCM delivered over 52 weeks offered no preset goals for maintenance behaviors and all changes in behavior were self-selected. Participants had a median BMI of 40.9 kg/m(2) and weight of 111 kg at the start of LMR. At LMR completion, they lost 18% (21 kg) of body weight. The SCM was completed by 22 patients (73%); 19 completers (86%) attended ≥ 17 of 20 sessions with a median satisfaction rating of 9 (on a scale of 1 to 9). Completers were asked to record self-selected maintenance behaviors daily (median 351 days recorded). The most commonly reported daily behaviors were self-weighing, use of meal replacements and step counting. Median percent regain at week 52 was 14% (2.8 kg) of lost weight (range, -42 to 74%), significantly less than a median of 56% (11 kg) percent regain of lost weight (range, -78 to 110%) in a demographically similar historical control group with no maintenance intervention after LMR completion (P<0.001). Thus, SCM holds promise for improving weight maintenance. Future research should compare SCM to standard maintenance programs that promote large program-directed changes. © 2013.

New York Power Authority/New York City Housing Authority refrigerator replacement program, first program year evaluation. Final report

Energy Technology Data Exchange (ETDEWEB)

Kinney, L.F.; Lewis, G. [Synertech Systems Corp., Syracuse, NY (United States); Pratt, R.G.; Miller, J. [Pacific Northwest National Lab., Richland, WA (United States)

1997-08-01

Acting as an energy services provider, the New York Power Authority (NYPA) has initiated a long-term project through which 20,000 refrigerators per year will be replaced with the most energy-efficient units possible in apartments managed by the New York City Housing Authority (NYCHA). Using bulk purchasing as an incentive to appliance manufacturers to produce energy-efficient refrigerators suitable for use in apartments, replaced in the first year of the program, which ended in December 1996. These units, kWh per year. Savings were determined by field testing and laboratory testing of 220 existing refrigerators and 56 newly-installed units. In the next program year, a 15.0-cubic-foot Maytag refrigerator, newly-designed in response to bulk purchasing incentives, is being installed. The new unit has a label rating of 437 kWh per year, 31 percent better than 1993 energy standards. Old refrigerators removed from apartments are {open_quotes}demanufactured{close_quotes} in an environmentally-appropriate way and both metals and refrigerants are recovered for reuse.

A REPRINT of a July 1991 Report to Congress, Executive Summary of Verification of Nuclear Warhead Dismantlement and Special Nuclear Material Controls

International Nuclear Information System (INIS)

Fuller, James L.

2008-01-01

With the renewed thinking and debate about deep reductions in nuclear weapons, including recent proposals about eliminating nuclear warheads altogether, republishing the general conclusions of the Robinson Committee Report of 1992 appears useful. The report is sometimes referred to as the 3151 Report, from Section 3151 of the National Defense Authorization Act for FY1991, from where its requirement originated. This report contains the Executive Summary only and the forwarding letters from the Committee, the President of the United States, the Secretary of Energy, and C Paul Robinson, the head of the Advisory Committee

30 CFR 823.14 - Soil replacement.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Soil replacement. 823.14 Section 823.14 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR PERMANENT PROGRAM PERFORMANCE STANDARDS SPECIAL PERMANENT PROGRAM PERFORMANCE STANDARDS-OPERATIONS ON PRIME FARMLAND § 823.14 Soil replacement. (a) Soil...

Redesigning a joint replacement program using Lean Six Sigma in a Veterans Affairs hospital.

Science.gov (United States)

Gayed, Benjamin; Black, Stephen; Daggy, Joanne; Munshi, Imtiaz A

2013-11-01

In April 2009, an analysis of joint replacement surgical procedures at the Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana, revealed that total hip and knee replacements incurred $1.4 million in non-Veterans Affairs (VA) care costs with an average length of stay of 6.1 days during fiscal year 2008. The Joint Replacement Program system redesign project was initiated following the Vision-Analysis-Team-Aim-Map-Measure-Change-Sustain (VA-TAMMCS) model to increase efficiency, decrease length of stay, and reduce non-VA care costs. To determine the effectiveness of Lean Six Sigma process improvement methods applied in a VA hospital. Perioperative processes for patients undergoing total joint replacement were redesigned following the VA-TAMMCS model--the VA's official, branded method of Lean Six Sigma process improvement. A multidisciplinary team including the orthopedic surgeons, frontline staff, and executive management identified waste in the current processes and initiated changes to reduce waste and increase efficiency. Data collection included a 1-year baseline period and a 20-month sustainment period. The primary endpoint was length of stay; a secondary analysis considered non-VA care cost reductions. Length of stay decreased 36% overall, decreasing from 5.3 days during the preproject period to 3.4 days during the 20-month sustainment period (P Lean and Six Sigma process improvement initiatives in a surgical practice, producing a 36% sustained reduction in length of stay and completely eliminating non-VA care for total hip and knee replacements while increasing total joint replacement volume at this medical center.

A.R.T. – Aggression Replacement Training

DEFF Research Database (Denmark)

Harbo, Lotte Junker; Domben, Eskil

2015-01-01

Artiklen indeholder en kort introduktion, eksemplificeret ved case, af det manualbaserede program til behandling af udadreagerende unge Aggression Replacement Training.......Artiklen indeholder en kort introduktion, eksemplificeret ved case, af det manualbaserede program til behandling af udadreagerende unge Aggression Replacement Training....

Design verification for reactor head replacement

International Nuclear Information System (INIS)

Dwivedy, K.K.; Whitt, M.S.; Lee, R.

2005-01-01

This paper outlines the challenges of design verification for reactor head replacement for PWR plants and the program for qualification from the prospective of the utility design engineering group. This paper is based on the experience with the design confirmation of four reactor head replacements for two plants, and their interfacing components, parts, appurtenances, and support structures. The reactor head replacement falls under the jurisdiction of the applicable edition of the ASME Section XI code, with particular reference to repair/replacement activities. Under any repair/replacement activities, demands may be encountered in the development of program and plan for replacement due to the vintage of the original design/construction Code and the design reports governing the component qualifications. Because of the obvious importance of the reactor vessel, these challenges take on an added significance. Additional complexities are introduced to the project, when the replacement components are fabricated by vendors different from the original vendor. Specific attention is needed with respect to compatibility with the original design and construction of the part and interfacing components. The program for reactor head replacement requires evaluation of welding procedures, applicable examination, test, and acceptance criteria for material, welds, and the components. Also, the design needs to take into consideration the life of the replacement components with respect to the extended period of operation of the plant after license renewal and other plant improvements. Thus, the verification of acceptability of reactor head replacement provides challenges for development and maintenance of a program and plan, design specification, design report, manufacturer's data report and material certification, and a report of reconciliation. The technical need may also be compounded by other challenges such as widely scattered global activities and organizational barriers, which

30 CFR 800.30 - Replacement of bonds.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Replacement of bonds. 800.30 Section 800.30... REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS UNDER REGULATORY PROGRAMS § 800.30 Replacement... replacement performance bonds. Replacement of a performance bond pursuant to this section shall not constitute...

24 CFR 970.31 - Replacement units.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Replacement units. 970.31 Section... PUBLIC HOUSING PROGRAM-DEMOLITION OR DISPOSITION OF PUBLIC HOUSING PROJECTS § 970.31 Replacement units. Notwithstanding any other provision of law, replacement public housing units may be built on the original public...

Efficacy of a Meal-Replacement Program for Promoting Blood Lipid Changes and Weight and Body Fat Loss in US Army Soldiers

Science.gov (United States)

2010-02-01

meal-replace- ent program (Slim-Fast Plan, Unilever , Englewood Cliffs, J) and were provided with all meal-replacement products nd snack bars (Slim-Fast...Optima, Unilever ). This group ill be referred to as “meal replacers” throughout the arti- le. Meal replacers were provided with calorie-controlled eal...snack bars (Slim-Fast Optima, Unilever , Englewood Cliffs, NJ).eficiencies in recording, including incomplete item de- t 70 February 2010 Volume 110 Number

Bibliography of Joint Aircraft Survivability Reports and Related Documents

Science.gov (United States)

1994-07-01

the GEN-X Model from ESAMS 1.5 to ESAMS 1.7 (U) 82 NWSC0CRAflfl JTCG/AS-91-SM-008 ROCOCO COLUMN Warhead Threat Performance Model (U) 83 JTCG/AS-91-SM...of the transition. 82 SM-3-17 JTCG/AS-91-SM-008 SECRET Title: ROCOCO COLUMN Warhead Threat Performance Model (U) Issued: February 1991 DTIC AD # Not...Lillard Gilbert Abstract: (U) The ROCOCO COLUMN Warhead Threat characterization program was conducted specifically to provide fragment weight, shape

User Interface Program for secure electronic tags

International Nuclear Information System (INIS)

Cai, Y.; Koehl, E.R.; Carlson, R.D.; Raptis, A.C.

1995-05-01

This report summarizes and documents the efforts of Argonne National Laboratory (ANL) in developing a secure tag communication user interface program comprising a tag monitor and a communication tool. This program can perform the same functions as the software that was developed at the Lawrence Livermore National Laboratory (LLNL), but it is enhanced with a user-friendly screen. It represents the first step in updating the TRANSCOM Tracking System (TRANSCOM) by incorporating a tag communication screen menu into the main menu of the TRANSCOM user program. A working version of TRANSCOM, enhanced with ANL secure-tag graphics, will strongly support the Department of Energy Warhead Dismantlement/Special Nuclear Materials Control initiatives. It will allow commercial satellite tracking of the movements and operational activities of treaty-limited items and transportation vehicles throughout Europe and the former USSR, as well as the continental US

An NMR-Guided Screening Method for Selective Fragment Docking and Synthesis of a Warhead Inhibitor

Directory of Open Access Journals (Sweden)

Ram B. Khattri

2016-07-01

Full Text Available Selective hits for the glutaredoxin ortholog of Brucella melitensis are determined using STD NMR and verified by trNOE and 15N-HSQC titration. The most promising hit, RK207, was docked into the target molecule using a scoring function to compare simulated poses to experimental data. After elucidating possible poses, the hit was further optimized into the lead compound by extension with an electrophilic acrylamide warhead. We believe that focusing on selectivity in this early stage of drug discovery will limit cross-reactivity that might occur with the human ortholog as the lead compound is optimized. Kinetics studies revealed that lead compound 5 modified with an ester group results in higher reactivity than an acrylamide control; however, after modification this compound shows little selectivity for bacterial protein versus the human ortholog. In contrast, hydrolysis of compound 5 to the acid form results in a decrease in the activity of the compound. Together these results suggest that more optimization is warranted for this simple chemical scaffold, and opens the door for discovery of drugs targeted against glutaredoxin proteins—a heretofore untapped reservoir for antibiotic agents.

An NMR-Guided Screening Method for Selective Fragment Docking and Synthesis of a Warhead Inhibitor.

Science.gov (United States)

Khattri, Ram B; Morris, Daniel L; Davis, Caroline M; Bilinovich, Stephanie M; Caras, Andrew J; Panzner, Matthew J; Debord, Michael A; Leeper, Thomas C

2016-07-16

Selective hits for the glutaredoxin ortholog of Brucella melitensis are determined using STD NMR and verified by trNOE and (15)N-HSQC titration. The most promising hit, RK207, was docked into the target molecule using a scoring function to compare simulated poses to experimental data. After elucidating possible poses, the hit was further optimized into the lead compound by extension with an electrophilic acrylamide warhead. We believe that focusing on selectivity in this early stage of drug discovery will limit cross-reactivity that might occur with the human ortholog as the lead compound is optimized. Kinetics studies revealed that lead compound 5 modified with an ester group results in higher reactivity than an acrylamide control; however, after modification this compound shows little selectivity for bacterial protein versus the human ortholog. In contrast, hydrolysis of compound 5 to the acid form results in a decrease in the activity of the compound. Together these results suggest that more optimization is warranted for this simple chemical scaffold, and opens the door for discovery of drugs targeted against glutaredoxin proteins-a heretofore untapped reservoir for antibiotic agents.

Nuclear weapons modernization: Plans, programs, and issues for Congress

Science.gov (United States)

Woolf, Amy F.

2017-11-01

The United States is currently recapitalizing each delivery system in its "nuclear triad" and refurbishing many of the warheads carried by those systems. The plans for these modernization programs have raised a number of questions, both within Congress and among analysts in the nuclear weapons and arms control communities, about the costs associated with the programs and the need to recapitalize each leg of the triad at the same time. This paper covers four distinct issues. It begins with a brief review of the planned modernization programs, then addresses questions about why the United States is pursuing all of these modernization programs at this time. It then reviews the debate about how much these modernization programs are likely to cost in the next decade and considers possible changes that might reduce the cost. It concludes with some comments about congressional views on the modernization programs and prospects for continuing congressional support in the coming years.

7 CFR 1944.659 - Replacement housing.

Science.gov (United States)

2010-01-01

... 7 Agriculture 13 2010-01-01 2009-01-01 true Replacement housing. 1944.659 Section 1944.659 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...) PROGRAM REGULATIONS (CONTINUED) HOUSING Housing Preservation Grants § 1944.659 Replacement housing...

Telerehabilitation Feasibility in Total Joint Replacement

Directory of Open Access Journals (Sweden)

Mark J. Nelson

2017-11-01

Full Text Available Despite documented benefits, many Total Joint Replacement (TJR patients find it difficult to access rehabilitation following discharge from hospital. One solution to improve access for TJR patients is telerehabilitation. This study aimed to assess the feasibility of introducing a telerehabilitation program for TJR patients.   TJR patients at QEII Jubilee Hospital were invited to complete a questionnaire regarding their access, feelings towards and preferences in using technology. Seventy-five patients were recruited. Most patients had computer access (72% and internet (69% at home. Sixty-five percent of participants were willing to participate in telerehabilitation. A significant difference was found between older and younger patients. Watching videos on an electronic device was the preferred method for a technology-based home exercise program and phone call the preferred method of communication.  Results indicate telerehabilitation in the TJR population is feasible from the perspective of access to, feelings toward, and preferences for technology. Keywords: Hip replacement, Knee replacement, Telerehabilitation, Telemedicine, Total joint replacement

Replacement of core components in the Advanced Test Reactor

International Nuclear Information System (INIS)

Durney, J.L.; Croucher, D.W.

1989-01-01

The core internals of the Advanced Test Reactor are subjected to very high neutron fluences resulting in significant aging. The most irradiated components have been replaced on several occasions as a result of the neutron damage. The surveillance program to monitor the aging developed the needed criteria to establish replacement schedules and maximize the use of the reactor. Methods to complete the replacements with minimum radiation exposures to workers have been developed using the experience gained from each replacement. The original design of the reactor core and associated components allows replacements to be completed without special equipment. The plant has operated for about 20 years and will continue operation for perhaps another 20 years. Aging evaluations are in program to address additional replacements that may be needed during this extended time period. 3 figs

A Water Rehabilitation Program in Patients with Hip Osteoarthritis Before and After Total Hip Replacement

OpenAIRE

?yp, Marek; Kaczor, Ryszard; Cabak, Anna; Tederko, Piotr; W?ostowska, Ewa; Stanis?awska, Iwona; Szypu?a, Jan; Tomaszewski, Wies?aw

2016-01-01

Background Pain associated with coxarthrosis, typically occurring in middle-aged and elderly patients, very commonly causes considerable limitation of motor fitness and dependence on pharmacotherapy. This article provides an assessment of a rehabilitation program with tailored water exercises in patients with osteoarthritis before and after total hip replacement. Material/Methods A total of 192 patients (the mean age 61.03?10.89) suffering from hip osteoarthritis (OA) were evaluated before an...

45 CFR 201.70 - Treatment of replacement checks.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false Treatment of replacement checks. 201.70 Section... STATES FOR PUBLIC ASSISTANCE PROGRAMS Review and Audits § 201.70 Treatment of replacement checks. (a... (FFP) for replacement checks under titles I, VI-A, X, XIV, XVI (AABD) except under the circumstances...

Discrete-continuous analysis of optimal equipment replacement

OpenAIRE

YATSENKO, Yuri; HRITONENKO, Natali

2008-01-01

In Operations Research, the equipment replacement process is usually modeled in discrete time. The optimal replacement strategies are found from discrete (or integer) programming problems, well known for their analytic and computational complexity. An alternative approach is represented by continuous-time vintage capital models that explicitly involve the equipment lifetime and are described by nonlinear integral equations. Then the optimal replacement is determined via the opt...

Scope Complexity Options Risks Excursions (SCORE) Version 3.0 Mathematical Description.

Energy Technology Data Exchange (ETDEWEB)

Gearhart, Jared Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Samberson, Jonell Nicole [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Shettigar, Subhasini [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jungels, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Welch, Kimberly M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Dean A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2017-03-01

The purpose of the Scope, Complexity, Options, Risks, Excursions (SCORE) model is to estimate the relative complexity of design variants of future warhead options. The results of this model allow those considering these options to understand the complexity tradeoffs between proposed warhead options. The core idea of SCORE is to divide a warhead option into a well- defined set of scope elements and then estimate the complexity of each scope element against a well understood reference system. The uncertainty associated with estimates can also be captured. A weighted summation of the relative complexity of each scope element is used to determine the total complexity of the proposed warhead option or portions of the warhead option (i.e., a National Work Breakdown Structure code). The SCORE analysis process is a growing multi-organizational Nuclear Security Enterprise (NSE) effort, under the management of the NA- 12 led Enterprise Modeling and Analysis Consortium (EMAC), that has provided the data elicitation, integration and computation needed to support the out-year Life Extension Program (LEP) cost estimates included in the Stockpile Stewardship Management Plan (SSMP).

An abstract machine for module replacement

OpenAIRE

Walton, Chris; Krl, Dilsun; Gilmore, Stephen

1998-01-01

In this paper we define an abstract machine model for the mλ typed intermediate language. This abstract machine is used to give a formal description of the operation of run-time module replacement from the programming language Dynamic ML. The essential technical device which we employ for module replacement is a modification of two-space copying garbage collection.

Restart Testing Program for piping following steam generator replacement at North Anna Unit 1

International Nuclear Information System (INIS)

Bain, R.A.; Bayer, R.K.

1993-01-01

In order to provide assurance that the effects of performing steam generator replacement (SGR) at North Anna unit 1 had no adverse impact on plant piping systems, a cold functional verification restart testing program was developed. This restart testing program was implemented in lieu of a hot functional testing program normally used during the initial startup of a nuclear plant. A review of North Anna plant-specific and generic U.S. Nuclear Regulatory Commission requirements for restart testing was performed to ensure that no mandatory hot functional testing was required. This was determined to be the case, and the development of a cold functional test program was initiated. The cold functional test had inherent advantages as compared to the hot functional testing, while still providing assurance of piping system adequacy. The advantages of the cold verification program included reducing risk to personnel from hot piping, increasing the accuracy of measurements with the improvement in work conditions, eliminating engineering activities during the heatup process, and being able to record measurements as construction work was completed allowing for rework or repair of components if required. To ensure the effectiveness of the cold verification program, a project procedure was generated to identify the personnel, equipment, and measurement requirements. An engineering calculation was issued to document the scope of the restart test program, and an additional calculation was developed to provide acceptance criteria for the critical commodity measurements

Lessons from a pilot program to induce stove replacements in Chile: design, implementation and evaluation

Science.gov (United States)

Gómez, Walter; Chávez, Carlos; Salgado, Hugo; Vásquez, Felipe

2017-11-01

We present the design, implementation, and evaluation of a subsidy program to introduce cleaner and more efficient household wood combustion technologies. The program was conducted in the city of Temuco, one of the most polluted cities in southern Chile, as a pilot study to design a new national stove replacement initiative for pollution control. In this city, around 90% of the total emissions of suspended particulate matter is caused by households burning wood. We created a simulated market in which households could choose among different combustion technologies with an assigned subsidy. The subsidy was a relevant factor in the decision to participate, and the inability to secure credit was a significant constraint for the participation of low-income households. Due to several practical difficulties and challenges associated with the implementation of large-scale programs that encourage technological innovation at the household level, it is strongly advisable to start with a small-scale pilot that can provide useful insights into the final design of a fuller, larger-scale program.

23 CFR 650.407 - Application for bridge replacement or rehabilitation.

Science.gov (United States)

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Application for bridge replacement or rehabilitation... ENGINEERING AND TRAFFIC OPERATIONS BRIDGES, STRUCTURES, AND HYDRAULICS Highway Bridge Replacement and Rehabilitation Program § 650.407 Application for bridge replacement or rehabilitation. (a) Agencies participate...

23 CFR 650.411 - Procedures for bridge replacement and rehabilitation projects.

Science.gov (United States)

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Procedures for bridge replacement and rehabilitation... ENGINEERING AND TRAFFIC OPERATIONS BRIDGES, STRUCTURES, AND HYDRAULICS Highway Bridge Replacement and Rehabilitation Program § 650.411 Procedures for bridge replacement and rehabilitation projects. (a) Consideration...

An abstract machine model of dynamic module replacement

OpenAIRE

Walton, Chris; Kırlı, Dilsun; Gilmore, Stephen

2000-01-01

In this paper we define an abstract machine model for the mλ typed intermediate language. This abstract machine is used to give a formal description of the operation of run-time module replacement for the programming language Dynamic ML. The essential technical device which we employ for module replacement is a modification of two-space copying garbage collection. We show how the operation of module replacement could be applied to other garbage-collected languages such as Java.

The effects of the empowerment education program in older adults with total hip replacement surgery.

Science.gov (United States)

Huang, Tzu-Ting; Sung, Chia-Chun; Wang, Woan-Shyuan; Wang, Bi-Hwa

2017-08-01

To measure the effectiveness of an education empowerment program on primary (self-efficacy and self-care competence) and secondary outcomes (Activities of Daily Life, mobility, depressive mood and quality of life) for older adults with total hip replacement surgery. Degenerative arthritis is a common and serious chronic illness that impacts the quality of life of older adults. As joints continue to degenerate and the hip damaged by arthritis, activities of daily life will be difficult to perform due to severe hip pain and joint stiffness. Therefore, hip replacement surgery should be considered and effective nursing care should be provided to improve the recovery of older adults. A prospective randomized control trial. A trial was conducted from September 2013 - May 2014 in two hospitals in northern Taiwan. 108 participants were random assigned to either the education empowerment group or in the comparison group. The researchers collected baseline data at admission and outcomes on the day of discharge, one month after and three months after the discharge. After the interventions, the education empowerment group participants demonstrated significantly higher self-care competence and self-efficacy and lower depressive inclinations compared with those in the comparison group. Participants in both groups significantly improved on activities of daily life, mobility and quality of life over the course of the interventions. This education empowerment intervention was very effective in enhancing participants' outcomes. Moreover, involving both older adults and their caregivers for the participation this program is recommended for a greater impact. © 2017 John Wiley & Sons Ltd.

Prioritization methodology for chemical replacement

Science.gov (United States)

Cruit, Wendy; Goldberg, Ben; Schutzenhofer, Scott

1995-01-01

to be quantitatively compared in several categories, and a QFD matrix which allows process/chemical pairs to be rated against one another for importance (using consistent categories). Depending on the need for application, one can choose the part(s) needed or have the methodology completed in its entirety. For example, if a program needs to show the risk of changing a process/chemical one may choose to use part of Matrix A and Matrix C. If a chemical is being used, and the process must be changed; one might use the Process Concerns part of Matrix D for the existing process and all possible replacement processes. If an overall analysis of a program is needed, one may request the QFD to be completed.

Development of an air cleaning system for dissolving high explosives from nuclear warheads

Energy Technology Data Exchange (ETDEWEB)

Bergman, W.; Wilson, K.; Staggs, K.; Wapman, D. [Lawrence Livermore National Lab., CA (United States)

1997-08-01

The Department of Energy (DOE) has a major effort underway in dismantling nuclear weapons. In support of this effort we have been developing a workstation for removing the high explosive (HE) from nuclear warheads using hot sprays of dimethyl sulfoxide (DMSO) solvent to dissolve the HE. An important component of the workstation is the air cleaning system that is used to contain DMSO aerosols and vapor and radioactive aerosols. The air cleaning system consists of a condenser to liquefy the hot DMSO vapor, a demister pad to remove most of the DMSO aerosols, a high efficiency particulate air (HEPA) filter to remove the remaining aerosols, an activated carbon filter to remove the DMSO vapor, and a final HEPA filter to meet the redundancy requirement for HEPA filters in radioactive applications. The demister pad is a 4{double_prime} thick mat of glass and steel fibers and was selected after conducting screening tests on promising candidates. We also conducted screening tests on various activated carbons and found that all had a similar performance. The carbon breakthrough curves were fitted to a modified Wheeler`s equation and gave excellent predictions for the effect of different flow rates. After all of the components were assembled, we ran a series of performance tests on the components and system to determine the particle capture efficiency as a function of size for dioctyl sebacate (DOS) and DMSO aerosols using laser particle counters and filter samples. The pad had an efficiency greater than 990% for 0.1 {mu}m DMSO particles. Test results on the prototype carbon filter showed only 70% efficiency, instead of the 99.9% in small scale laboratory tests. Thus further work will be required to develop the prototype carbon filter. 7 refs., 18 figs., 10 tabs.

Long-Term Weight-Loss Maintenance by a Meal Replacement Based Weight Management Program in Primary Care

Directory of Open Access Journals (Sweden)

Renate Kruschitz

2017-04-01

Full Text Available Objective: Structured obesity treatment programs at primary care level are becoming increasingly important. However, evidence from current treatment approaches in the long term is lacking. In view of this fact we evaluated a standardized, meal replacement-based weight loss program (myLINE®; AENGUS, Graz, Austria according to the currently applicable guidelines. Methods: Data of overweight and obese individuals (n = 70 who participated at least 36 months in the program were analyzed. Data were collected at baseline (T0 as well as after 1, 3, 6, 12, 24, and 36 (T1-T36 months. Body composition was measured by conventional anthropometry and bioelectrical impedance analysis. Results: Compared to T0, a maximum weight, BMI, fat mass, absolute body cell mass (BCM reduction and an increase of relative BCM could be seen at T6. Subsequently, the findings reveal a significant reduction of body weight and body fat and a satisfying development of body cell mass during the observation period of 36 months. Conclusion: The evaluated program complies with national and international guidelines for the therapy of obesity in adults and is efficient and meaningful for a long-term therapeutic use in primary care..

Prioritizing equipment for replacement.

Science.gov (United States)

Capuano, Mike

2010-01-01

It is suggested that clinical engineers take the lead in formulating evaluation processes to recommend equipment replacement. Their skill, knowledge, and experience, combined with access to equipment databases, make them a logical choice. Based on ideas from Fennigkoh's scheme, elements such as age, vendor support, accumulated maintenance cost, and function/risk were used.6 Other more subjective criteria such as cost benefits and efficacy of newer technology were not used. The element of downtime was also omitted due to the data element not being available. The resulting Periop Master Equipment List and its rationale was presented to the Perioperative Services Program Council. They deemed the criteria to be robust and provided overwhelming acceptance of the list. It was quickly put to use to estimate required capital funding, justify items already thought to need replacement, and identify high-priority ranked items for replacement. Incorporating prioritization criteria into an existing equipment database would be ideal. Some commercially available systems do have the basic elements of this. Maintaining replacement data can be labor-intensive regardless of the method used. There is usually little time to perform the tasks necessary for prioritizing equipment. However, where appropriate, a clinical engineering department might be able to conduct such an exercise as shown in the following case study.

Replacement of core components in the Advanced Test Reactor

International Nuclear Information System (INIS)

Durney, J.L.; Croucher, D.W.

1990-01-01

The core internals of the Advanced Test Reactor are subjected to very high neutron fluences resulting in significant aging. The most irradiated components have been replaced on several occasions as a result of the neutron damage. The surveillance program to monitor the aging developed the needed criteria to establish replacement schedules and maximize the use of the reactor. The methods to complete the replacements with minimum radiation exposures to workers have been developed using the experience gained from each replacement. The original design of the reactor core and associated components allows replacements to be completed without special equipment. The plant has operated for about 20 years and is expected to continue operation for at least and additional 25 years. Aging evaluations are in progress to address additional replacements that may be needed during this period

Comparison of Four Estimators under sampling without Replacement

African Journals Online (AJOL)

The results were obtained using a program written in Microsoft Visual C++ programming language. It was observed that the two-stage sampling under unequal probabilities without replacement is always better than the other three estimators considered. Keywords: Unequal probability sampling, two-stage sampling, ...

Medicare Program; Comprehensive Care for Joint Replacement Payment Model for Acute Care Hospitals Furnishing Lower Extremity Joint Replacement Services. Final rule.

Science.gov (United States)

2015-11-24

This final rule implements a new Medicare Part A and B payment model under section 1115A of the Social Security Act, called the Comprehensive Care for Joint Replacement (CJR) model, in which acute care hospitals in certain selected geographic areas will receive retrospective bundled payments for episodes of care for lower extremity joint replacement (LEJR) or reattachment of a lower extremity. All related care within 90 days of hospital discharge from the joint replacement procedure will be included in the episode of care. We believe this model will further our goals in improving the efficiency and quality of care for Medicare beneficiaries with these common medical procedures.

Equipment Replacement Decision Making: Opportunities and Challenges

OpenAIRE

Fan, Wei (David); Gemar, Mason D.; Machemehl, Randy

2012-01-01

The primary function of equipment managers is to replace the right equipment at the right time and at the lowest overall cost. In this paper, the opportunities and challenges associated with equipment replacement optimization (ERO) are discussed in detail. First, a comprehensive review of the state-of-the art and state-of-the practice literature for the ERO problem is conducted. Second, a dynamic programming (DP) based optimization solution methodology is presented to solve the ERO problem. T...

Long-Term Weight-Loss Maintenance by a Meal Replacement Based Weight Management Program in Primary Care.

Science.gov (United States)

Kruschitz, Renate; Wallner-Liebmann, Sandra; Lothaller, Harald; Luger, Maria; Ludvik, Bernhard

2017-01-01

Structured obesity treatment programs at primary care level are becoming increasingly important. However, evidence from current treatment approaches in the long term is lacking. In view of this fact we evaluated a standardized, meal replacement-based weight loss program (myLINE®; AENGUS, Graz, Austria) according to the currently applicable guidelines. Data of overweight and obese individuals (n = 70) who participated at least 36 months in the program were analyzed. Data were collected at baseline (T0) as well as after 1, 3, 6, 12, 24, and 36 (T1-T36) months. Body composition was measured by conventional anthropometry and bioelectrical impedance analysis. Compared to T0, a maximum weight, BMI, fat mass, absolute body cell mass (BCM) reduction and an increase of relative BCM could be seen at T6. Subsequently, the findings reveal a significant reduction of body weight and body fat and a satisfying development of body cell mass during the observation period of 36 months. The evaluated program complies with national and international guidelines for the therapy of obesity in adults and is efficient and meaningful for a long-term therapeutic use in primary care.. © 2017 The Author(s) Published by S. Karger GmbH, Freiburg.

Moderator inlet line hanger replacement for Pickering nuclear power station

International Nuclear Information System (INIS)

Kirkpatrick, R.A.; Bowman, J.M.; Symmons, W.R.; El-Nesr, S.

1988-01-01

Ontario Hydro's Pickering Nuclear Generating Station (PNGS), Units 1 and 2 were shutdown for large scale fuel channel replacement. Other nonroutine inspection and maintenance activities were performed to determine the overall condition of the units and it was seen that a moderator inlet line hanger (identified as HR-29) had failed in both units. Subsequent inspections during planned maintenance outages of Pickering NGS Units 3 and 4 revealed that hanger HR-29 had failed and required replacement. A research program was conducted to find a suitable technique. These problems included accessing tooling through small inspection ports, manipulating tooling from a significant distance and the high radiation fields within the vault. This paper describes the program undertaken to replace hanger HR-29. (author)

The impact of a weight reduction program with and without meal-replacement on health related quality of life in middle-aged obese females.

Science.gov (United States)

Koohkan, Sadaf; Schaffner, Denise; Milliron, Brandy J; Frey, Ingrid; König, Daniel; Deibert, Peter; Vitolins, Mara; Berg, Aloys

2014-03-12

In addition to an increased risk for chronic illnesses, obese individuals suffer from social stigmatization and discrimination, and severely obese people may experience greater risk of impaired psychosocial and physical functioning. Lower health-related quality of life (HRQOL) has been reported among obese persons seeking intensive treatment for their disease. To aid in the treatment of obesity, meal replacements have been recommended as an effective therapeutic strategy for weight loss, particularly when consumed in the beginning of an intervention. Hence, the objective of this study was to assess the impact of two 12-month weight reduction interventions (one arm including a meal replacement) on changes in HRQOL among obese females. This controlled trial compared two versions of a standardized 12-month weight reduction intervention: the weight-reduction lifestyle program without a meal replacement (LS) versus the same lifestyle program with the addition of a soy-based meal replacement product (LSMR). 380 women (LS: n = 190, LSMR: n = 190) were matched by age, gender, and weight (51.4 ± 7.0 yrs., 35.5 ± 3.03 kg/m2). This sample of women all completed the 12-month lifestyle intervention that was part of a larger study. The lifestyle intervention included instruction on exercise/sport, psychology, nutrition, and medicine in 18 theoretical and 40 practical units. Led by a sport physiologist, participants engaged in group-based exercise sessions once or twice a week. To evaluate HRQOL, all participants completed the SF-36 questionnaire pre- and post-intervention. Anthropometric, clinical, physical performance (ergometric stress tests), and self-reported leisure time physical activity (hours/day) data were collected. The LSMR sample showed lower baseline HRQOL scores compared to the LS sample in six of eight HRQOL dimensions, most significant in vitality and health perception (p meal replacement product. ClinicalTrials.gov NCT00356785.

A comprehensive joint replacement program for total knee arthroplasty: a descriptive study

Directory of Open Access Journals (Sweden)

Prefontaine Paul

2008-11-01

Full Text Available Abstract Background Total knee arthroplasty (TKA is a commonly performed surgical procedure in the US. It is important to have a comprehensive inpatient TKA program which maximizes outcomes while minimizing adverse events. The purpose of this study was to describe a TKA program – the Joint Replacement Program (JRP – and report post-surgical outcomes. Methods 74 candidates for a primary TKA were enrolled in the JRP. The JRP was designed to minimize complications and optimize patient-centered outcomes using a team approach including the patient, patient's family, and a multidisciplinary team of health professionals. The JRP consisted of a pre-operative class, standard pathways for medical care, comprehensive peri-operative pain management, aggressive physical therapy (PT, and proactive discharge planning. Measures included functional tests, knee range of motion (ROM, and medical record abstraction of patient demographics, length of stay, discharge disposition, and complications over a 6-month follow-up period. Results All patients achieved medical criteria for hospital discharge. The patients achieved the knee flexion ROM goal of 90° (91.7 ± 5.4°, but did not achieve the knee extension ROM goal of 0° (2.4 ± 2.6°. The length of hospital stay was two days for 53% of the patients, with 39% and 7% discharged in three and four days, respectively. All but three patients were discharged home with functional independence. 68% of these received outpatient physical therapy compared with 32% who received home physical therapy immediately after discharge. Two patients ( Conclusion The comprehensive JRP for TKA was associated with satisfactory clinical outcomes, short lengths of stay, a high percentage of patients discharged home with outpatient PT, and minimal complications. This JRP may represent an efficient, effective and safe protocol for providing care after a TKA.

Who Will Replace Those Vanishing Execs?

Science.gov (United States)

Geber, Beverly

2000-01-01

Many top-level managers are retiring early. Programs to prepare their replacements have been scaled back. Many companies are offering phased retirement plans, redesigning jobs, and paying for spouses to go along on business trips to keep their managers a little longer. (JOW)

Investigation of gamma spectra analysis

International Nuclear Information System (INIS)

Wu Huailong; Liu Suping; Hao Fanhua; Gong Jian; Liu Xiaoya

2006-01-01

In the investigation of radiation fingerprint comparison, it is found out that some of the popular gamma spectra analysis software have shortcomings, which decrease the radiation fingerprint comparison precision. So a new analysis software is developed for solving the problems. In order to display the advantage of developed program, some typical simulative warhead gamma spectra are analyzed respectively by present software and GAMMAVISION and GENNIE2000. Present software can be applied not only in nuclear warheads deep-cuts verification, but also in any radiation measurement field. (authors)

Optimal Replacement Policy of Jet Engine Modules from the Aircarrier's Point of View

Directory of Open Access Journals (Sweden)

Anita Domitrović

2008-01-01

Full Text Available A mathematical model for optimising preventive maintenanceof aircraft jet engine was developed by dynamic programming.Replacement planning for jet engine modules is regardedas a multistage decision process, while optimum modulereplacement is considered as a problem of equipment replacement.The goal of the optimal replacement policy of jet enginemodules is a defined series of decisions resulting in minimummaintenance costs. The model was programmed inC++ programming language and tested by using CFM56 jetengine data. The optimum maintenance strategy costs werecompared to costs of simpler experience-based maintenancestrategies. The results of the comparison j usti.JY further developmentand usage of the model in order to achieve significant costreduction for airline carriers.

Pressure tube replacement in Pickering NGS A units 1 and 2

International Nuclear Information System (INIS)

Irvine, H.S.; Bennett, E.J.; Talbot, K.H.

1986-10-01

Being able to technically and economically replace the most radioactive components (excluding the nuclear fuel) in operating reactors will help to ensure the ongoing acceptance of nuclear power as a viable energy source for the future. Ontario Hydro is well along the path to meeting the above objective for its CANDU-PHW reactors. Following the failure of a Zircaloy-II pressure tube in unit 2 of Pickering NGS A in August, 1983, Ontario Hydro has embarked on a program to replace all Zircaloy-II pressure tubes in units 1 and 2 at Pickering. This program integrates the in-house research, design, construction, and operating skills of a large utility (Ontario Hydro) with the skills of a national nuclear organization (Atomic Energy of Canada Limited) and the private engineering sector of the Canadian nuclear industry. The paper describes the background to the pressure tube failure in Pickering unit 2 and to the efforts incurred in understanding the failure mechanism and how similar failures are not expected for the zirconium-niobium pressure tube material used in all other large CANDU-PHW units after units 1 and 2 of Pickering NGS A. The tooling developed for the pressure tube replacement program is described as well as the organization to undertake the program in an operating nuclear station. The retubing of units 1 and 2 at Pickering NGS A is nearing a successful completion and shows the benefits of being able to integrate the various skills required for this success. Pressure tube replacement in a CANDU-PHW reactor is equivalent to replacement of the reactor vessel in a LWR. The fact that this replacement can be done economically and with acceptable radiation dose to workers augurs well for the continued viability of the use of nuclear energy for the benefit of mankind. (author)

Technical development and its application on steam generator replacement

International Nuclear Information System (INIS)

Morita, Sadahiko; Hanzawa, Katsumi; Sato, Hajime; Kannoto, Yasuo.

1995-01-01

Twenty-two PWR nuclear power plants are now under commercial operation in Japan. Eight of these plants are scheduled to have their steam generators replaced by up-graded units as a social responsibility for improved reliability, economy and easier maintenance. To carry out steam generator replacement, main coolant pipe cutting and restoration techniques, remote controlled welding machines and other remote controlled equipment, templating techniques with which the new steam generator primary nozzles will fit the existing primary pipes correctly were developed. An adequate training program was carried out to establish these techniques and they were then applied in replacement work on site. The steam generators of the three plants were replaced completely in 1994. These newly developed techniques are to be applied in upcoming plants and replaced plants will be much reliable. (author)

Steam generator replacement at Surry Power Station

International Nuclear Information System (INIS)

McKay, H.S.

1982-01-01

The purposes of the steam generator repair program at Surry Power Station were to repair the tube degradation caused by corrosion-related phenomena and to restore the integrity of the steam generators to a level equivalent to new equipment. The repair program consisted of (1) replacing the existing lower-shell assemblies with new ones and (2) adding new moisture separation equipment to the upper-shell assemblies. These tasks required that several pieces of reactor coolant piping, feedwater piping, main steam piping, and the steam generator be cut and refurbished for reinstallation after the new lower shell was in place. The safety implications and other potential effects of the repair program both during the repair work and after the unit was returned to power were part of the design basis of the repair program. The repair program has been completed on Unit 2 without any adverse effects on the health and safety of the general public or to the personnel engaged in the repair work. Before the Unit 1 repair program began, a review of work procedures and field changes for the Unit 2 repair was conducted. Several major changes were made to avoid recurrence of problems and to streamline procedures. Steam generator replacements was completed on June 1, 1981, and the unit is presently in the startup phase of the outrage

Reactor console replacement at Washington State University

International Nuclear Information System (INIS)

Lovas, Thomas A.

1978-01-01

A replacement reactor console was installed in 1977 at the W.S.U. 1 MW TRIGA-fueled reactor as the final step in an instrumentation upgrade program. The program was begun circa 1972 with the design, construction and installation of various systems and equipment. Major instruments were installed in the existing console and tested in the course of reactor operation. The culmination of the program was the installation of a cubicle designed and constructed to house the updated instrumentation. (author)

Optimum body size of Holstein replacement heifers.

Science.gov (United States)

Hoffman, P C

1997-03-01

Criteria that define optimum body size of replacement heifers are required by commercial dairy producers to evaluate replacement heifer management programs. Historically recommended body size criteria have been based on live BW measurements. Numerous research studies have observed a positive relationship between BW at first calving and first lactation milk yield, which has served as the impetus for using live BW to define body size of replacement heifers. Live BW is, however, not the only available measurement to define body size. Skeletal measurements such as wither height, length, and pelvic area have been demonstrated to be related to first lactation performance and (or) dystocia. Live BW measurements also do not define differences in body composition. Differences in body composition of replacement heifers at first calving are also related to key performance variables. An updated research data base is available for the modern Holstein genotype to incorporate measures of skeletal growth and body composition with BW when defining body size. These research projects also lend insight into the relative importance of measurements that define body size of replacement heifers. Incorporation of these measurements from current research into present BW recommendations should aid commercial dairy producers to better define replacement heifer growth and management practices. This article proposes enhancements in defining optimum body size and growth characteristics of Holstein replacement heifers.

HIBAL Program. Preliminary Warhead-Design. Volume II. Appendices.

Science.gov (United States)

1980-09-15

Mild Steel (iAi i018). ............. 11-2 B. SAE 4130 .. .. .. .... ...... ....... 11-3 C. SAE 4140 ......... .... .... ......... 11-3 D, SAE 4340...11-7 - Test Data for SAE 4140 Steel Frag- ments ...... ................ 11-14 Figure II-7A - 4142 ... .............. 11-15 Figure 11-8 - Test Data...included the following types of steel: SAE 1018, 4130, 4140 and 4340; 5-317 and 5-876 Carpenter tool steel; Anico HY-80 and SSS-100 steel; AISI-S7

Implementation strategy for achieving replacement level fertility.

Science.gov (United States)

1993-01-01

The recommendation of the Bali Declaration on Population and Sustainable Development at the ESCAP regional conference was to adopt strategies for attaining replacement-level fertility of 2.1 or 2.2 children by 2010. East Asian countries, except Mongolia and the Democratic People's Republic of Korea, and the Southeast Asian countries Singapore and Thailand have already reached replacement-level fertility. Most larger Oceanic countries have also done so. Only South Asian Sri Lanka and southern India have attained replacement level. The following conditions slow or hinder the goal, but they do not provide an "absolute" barrier to fertility decline: social welfare schemes and old age security, son preference, lack of government family planning, poverty, relatively high mortality, low status of women, and education status. Theories of demographic transition have postulated that economic and social development initially brings a decline in mortality, and later brings a decline in fertility; and high fertility was an adaptation to high mortality. Policy gets caught in the lag between mortality and fertility decline. Eventually the cultural motives for high fertility are undercut by social and economic development. Although the generalization that economic growth slows fertility is true for South Asia, the correlation is uneven. Forceful government-sponsored family planning programs in Bangladesh and China may lead the way to strategies for decline in ESCAP region. A Thailand study suggested important factors were fundamental social change, the increased cost of children, cultural acceptance of birth control, a latent demand for fertility control, and government efforts in family planning. ESCAP countries have in common relatively high morality and inadequate public health programs, patriarchal structures, and limited female autonomy, poverty and landlessness, lack of community cohesiveness, and inadequate family planning programs. Weaknesses in programs are attributed to

Air Traffic Control: Status of FAA's Implementation of the Display System Replacement Project

National Research Council Canada - National Science Library

1999-01-01

...) implementation of the Display System Replacement (DSR) project. DSR, which replaces the controllers' workstations and other equipment in the nation's en route centers, is one of FAA's major projects under the air traffic control modernization program...

Risk factors for urinary retention after hip or knee replacement: a cohort study

OpenAIRE

Griesdale, Donald E. G.; Neufeld, Jeremy; Dhillon, Dale; Joo, Jennifer; Sandhu, Supna; Swinton, Frank; Choi, Peter T.

2011-01-01

Introduction In 2006, our provincial government initiated a program to reduce wait times for total hip or knee replacements by referring patients to a single tertiary-care centre. This program provided an opportunity to identify risk factors for perioperative complications as part of a continuing quality improvement project. We report the risk of postoperative urinary retention after hip and knee replacements and the risk factors associated with this complication. Methods After local Research...

Guideline for the seismic technical evaluation of replacement items for nuclear power plants

International Nuclear Information System (INIS)

Harris, S.P.; Cushing, R.W.; Johnson, H.W.; Abeles, J.M.

1993-02-01

Seismic qualification for equipment originally installed in nuclear power plants was typically performed by the original equipment suppliers or manufactures (OES/OEM). Many of the OES/OEM no longer maintain quality assurance programs with adequate controls for supplying nuclear equipment. Utilities themselves must provide reasonable assurance in the continued seismic adequacy of such replacement items. This guideline provides practical, cost-effective techniques which can be used to provide reasonable assurance that replacement items will meet seismic performance requirements necessary to maintain the seismic design basis of commercial nuclear power plants. It also provides a method for determining when a seismic technical evaluation of replacement items (STERI) is required as part of the procurement process for spare and replacement items. Guidance on supplier program requirements necessary to maintain continued seismic adequacy and on documentation of maintaining required seismic adequacy is also included

Why are U.S. nuclear weapon modernization efforts controversial?

Science.gov (United States)

Acton, James

2016-03-01

U.S. nuclear weapon modernization programs are focused on extending the lives of existing warheads and developing new delivery vehicles to replace ageing bombers, intercontinental ballistic missiles, and ballistic missile submarines. These efforts are contested and controversial. Some critics argue that they are largely unnecessary, financially wasteful and potentially destabilizing. Other critics posit that they do not go far enough and that nuclear weapons with new military capabilities are required. At its core, this debate centers on three strategic questions. First, what roles should nuclear weapons be assigned? Second, what military capabilities do nuclear weapons need to fulfill these roles? Third, how severe are the unintended escalation risks associated with particular systems? Proponents of scaled-down modernization efforts generally argue for reducing the role of nuclear weapons but also that, even under existing policy, new military capabilities are not required. They also tend to stress the escalation risks of new--and even some existing--capabilities. Proponents of enhanced modernization efforts tend to advocate for a more expansive role for nuclear weapons in national security strategy. They also often argue that nuclear deterrence would be enhanced by lower yield weapons and/or so called bunker busters able to destroy more deeply buried targets. The debate is further fueled by technical disagreements over many aspects of ongoing and proposed modernization efforts. Some of these disagreements--such as the need for warhead life extension programs and their necessary scope--are essentially impossible to resolve at the unclassified level. By contrast, unclassified analysis can help elucidate--though not answer--other questions, such as the potential value of bunker busters.

Enhancing the growth performance of replacement female breeder goats through modification of feeding program

Directory of Open Access Journals (Sweden)

A. A. A. Ghani

2017-06-01

Full Text Available Aim: The study was conducted at a smallholder goat farm located in Labu, Negeri Sembilan, Malaysia. The objective of this study was to evaluate the effect of proper feeding program on growth performances of replacement breeder goats. Materials and Methods: A total of 30 healthy female boer cross goats at the age of 4 months old with average initial live body weight (BW of 20.05±0.5 kg were used for on-farm feeding trial to evaluate the growth performance as preparation for breeding purposes. The experimental goats were divided into two groups of 15 animals each labeled as control and treatment groups, which were kept under intensive farming system. Goats in control group were fed with normal routine feeding protocol practiced by the farmer, while goats in the treatment group were fed with new feed formulation. Throughout the experimental period, on-farm monitoring and data collection were carried out. Initial BW and body condition score (BCS were recorded before the start of the experiment while final BW and BCS were gained after 7 months of the experimental period. Average daily gain (ADG was calculated after the experiment end. Data on BW, ADG, and BCS were recorded from both groups for every 2 weeks and reported monthly. The feed intake for the control group was 2.8 kg/animal/day which practiced by the farmer and 3.2 kg/animal/day as new feed formulation for the treatment group. Results: After 7 months of the experimental period, final BW shows an improvement in treatment group (39.1±1.53 kg compared with control group (32.3±1.23 kg. The ADG in treatment group also gives promising result when comparing with control group. Goats in treatment group significantly attained better ADG than control group which were 126.7 g/day and 83.3 g/day, respectively. For the BCS, goats in the treatment group had shown an improvement where 86.67% (13 out of 15 of the group had BCS =3 (1-5 scoring scale and only 66.67% (10 out of 15 of the control group had

Hip joint replacement

Science.gov (United States)

Hip arthroplasty; Total hip replacement; Hip hemiarthroplasty; Arthritis - hip replacement; Osteoarthritis - hip replacement ... Your hip joint is made up of 2 major parts. One or both parts may be replaced during surgery: ...

Contribution of V(H replacement products in mouse antibody repertoire.

Directory of Open Access Journals (Sweden)

Lin Huang

Full Text Available VH replacement occurs through RAG-mediated recombination between the cryptic recombination signal sequence (cRSS near the 3' end of a rearranged VH gene and the 23-bp RSS from an upstream unrearranged VH gene. Due to the location of the cRSS, VH replacement leaves a short stretch of nucleotides from the previously rearranged VH gene at the newly formed V-D junction, which can be used as a marker to identify VH replacement products. To determine the contribution of VH replacement products to mouse antibody repertoire, we developed a Java-based VH Replacement Footprint Analyzer (VHRFA program and analyzed 17,179 mouse IgH gene sequences from the NCBI database to identify VH replacement products. The overall frequency of VH replacement products in these IgH genes is 5.29% based on the identification of pentameric VH replacement footprints at their V-D junctions. The identified VH replacement products are distributed similarly in IgH genes using most families of VH genes, although different families of VH genes are used differentially. The frequencies of VH replacement products are significantly elevated in IgH genes derived from several strains of autoimmune prone mice and in IgH genes encoding autoantibodies. Moreover, the identified VH replacement footprints in IgH genes from autoimmune prone mice or IgH genes encoding autoantibodies preferentially encode positively charged amino acids. These results revealed a significant contribution of VH replacement products to the diversification of antibody repertoire and potentially, to the generation of autoantibodies in mice.

Shoulder replacement - discharge

Science.gov (United States)

Total shoulder arthroplasty - discharge; Endoprosthetic shoulder replacement - discharge; Partial shoulder replacement - discharge; Partial shoulder arthroplasty - discharge; Replacement - shoulder - discharge; Arthroplasty - shoulder - discharge

Replacing penalties

Directory of Open Access Journals (Sweden)

Vitaly Stepashin

2017-01-01

Full Text Available УДК 343.24The subject. The article deals with the problem of the use of "substitute" penalties.The purpose of the article is to identify criminal and legal criteria for: selecting the replacement punishment; proportionality replacement leave punishment to others (the formalization of replacement; actually increasing the punishment (worsening of legal situation of the convicted.Methodology.The author uses the method of analysis and synthesis, formal legal method.Results. Replacing the punishment more severe as a result of malicious evasion from serving accused designated penalty requires the optimization of the following areas: 1 the selection of a substitute punishment; 2 replacement of proportionality is serving a sentence other (formalization of replacement; 3 ensuring the actual toughening penalties (deterioration of the legal status of the convict. It is important that the first two requirements pro-vide savings of repression in the implementation of the replacement of one form of punishment to others.Replacement of punishment on their own do not have any specifics. However, it is necessary to compare them with the contents of the punishment, which the convict from serving maliciously evaded. First, substitute the punishment should assume a more significant range of restrictions and deprivation of certain rights of the convict. Second, the perfor-mance characteristics of order substitute the punishment should assume guarantee imple-mentation of the new measures.With regard to replacing all forms of punishment are set significant limitations in the application that, in some cases, eliminates the possibility of replacement of the sentence, from serving where there has been willful evasion, a stricter measure of state coercion. It is important in the context of the topic and the possibility of a sentence of imprisonment as a substitute punishment in cases where the original purpose of the strict measures excluded. It is noteworthy that the

Optimal Overhaul-Replacement Policies for Repairable Machine Sold with Warranty

Directory of Open Access Journals (Sweden)

Kusmaningrum Soemadi

2014-12-01

Full Text Available This research deals with an overhaul-replacement policy for a repairable machine sold with Free Replacement Warranty (FRW. The machine will be used for a finite horizon, T (T <, and evaluated at a fixed interval, s (s< T. At each evaluation point, the buyer considers three alternative decisions i.e. Keep the machine, Overhaul it, or Replace it with a new identical one. An overhaul can reduce the machine age virtually, but not to a point that the machine is as good as new. If the machine fails during the warranty period, it is rectified at no cost to the buyer. Any failure occurring before and after the expiry of the warranty is restored by minimal repair. An overhaul-replacement policy is formulated for such machines by using dynamic programming approach to obtain the buyer’s optimal policy. The results show that a significant rejuvenation effect due to overhaul may extend the length of machine life cycle and delay the replacement decision. In contrast, the warranty stimulates early machine replacement and by then increases the replacement frequencies for a certain range of replacement cost. This demonstrates that to minimize the total ownership cost over T the buyer needs to consider the minimal repair cost reduction due to rejuvenation effect of overhaul as well as the warranty benefit due to replacement. Numerical examples are presented for both illustrating the optimal policy and describing the behavior of the optimal solution.

U.S. Strategic Nuclear Forces: Background, Developments, and Issues

Science.gov (United States)

2017-02-10

Cost $85 Billion,” Bloomberg News , September 6, 2016. 62 Aaron Mehta, “Planned ICBM Replacement To Move Forward Without Consensus,” Defense News ...bombers, consistent with the terms of the New START Treaty, it also plans to develop new delivery systems for deployment over the next 20-30 years. The 115...1,550 deployed warheads in 2018, after the New START Treaty completes implementation. At the present time, the U.S. land-based ballistic missile force

Ankle replacement

Science.gov (United States)

Ankle arthroplasty - total; Total ankle arthroplasty; Endoprosthetic ankle replacement; Ankle surgery ... Ankle replacement surgery is most often done while you are under general anesthesia. This means you will ...

75 FR 33268 - Technology Innovation Program (TIP) Notice of Availability of Funds; Amendment

Science.gov (United States)

2010-06-11

... military/ weaponry applications (e.g. warhead manufacture, chemical/biological warfare materials production.... production of biofuels or small molecule drugs); Projects that primarily focus on drug discovery or design of... design that are not a part of the manufacturing of engineered tissues; and Projects that do not have a...

Nicotine replacement therapy

Science.gov (United States)

Smoking cessation - nicotine replacement; Tobacco - nicotine replacement therapy ... Before you start using a nicotine replacement product, here are some things to know: The more cigarettes you smoke, the higher the dose you may need to ...

Lower bounds for protrusion replacement by counting equivalence classes

NARCIS (Netherlands)

Jansen, B.M.P.; Wulms, J.J.H.M.; Guo, J.; Hermelin, D.

2017-01-01

Garnero et al. [SIAM J. Discrete Math. 2015, 29(4):1864-1894] recently introduced a framework based on dynamic programming to make applications of the protrusion replacement technique constructive and to obtain explicit upper bounds on the involved constants. They show that for several graph

Lower bounds for protrusion replacement by counting equivalence classes

NARCIS (Netherlands)

Jansen, B.M.P.; Wulms, J.J.H.M.

2016-01-01

Garnero et al. [SIAM J. Discrete Math. 2015, 29(4):1864--1894] recently introduced a framework based on dynamic programming to make applications of the protrusion replacement technique constructive and to obtain explicit upper bounds on the involved constants. They show that for several graph

Hip Replacement Surgery

Science.gov (United States)

... Outreach Initiative Breadcrumb Home Health Topics English Español Hip Replacement Surgery Basics In-Depth Download Download EPUB ... PDF What is it? Points To Remember About Hip Replacement Surgery Hip replacement surgery removes damaged or ...

CH-53K Heavy Lift Replacement Helicopter (CH-53K)

Science.gov (United States)

2015-12-01

Selected Acquisition Report (SAR) RCS: DD-A&T(Q&A)823-390 CH-53K Heavy Lift Replacement Helicopter (CH-53K) As of FY 2017 President’s Budget...December 2015 SAR March 4, 2016 10:04:18 UNCLASSIFIED 4 Col Henry Vanderborght PMA-261 Heavy Lift Helicopters Program Executive Office - Air, Anti...757-5780 Fax: 301-757-5109 DSN Phone: 757-5780 DSN Fax: 757-5109 Date Assigned: May 29, 2014 Program Information Program Name CH-53K Heavy Lift

Strategic provisioning of replacement parts for CANDU power plants

International Nuclear Information System (INIS)

Mizuno, G.; Tume, P.; Prentice, J.

2000-01-01

Provisioning of replacement parts and management of critical spares are key factors in optimizing maintenance programs for CANDU power plants. With a view to supply assurance, Atomic Energy Canada Limited (AECL) has created a Spare Parts Branch (SPB) to provide a clear pipeline from the client to the delivered replacement part(s). SPB provides the client with assured access to a qualified supplier database, computer aided design, engineering and manufacturing services and material upgrades and design registration through the authorized inspection agency. The AECL spare parts strategic provisioning service plan that has four thrusts: 1) the efficient delivery of cost-effective replacement parts; 2) obsolete parts resolution; 3) a website that will provide our clients with real-time access to replacement part data; and 4) inventory recovery opportunities. Thrusts one and two are actively ensuring plant maintenance for on-shore and off-shore CANDU clients. Thrusts three and four are longer-term commitments. This paper will explore these thrusts in the context of our CANDU business practices. (author)

Suborbital Platforms as a Tool for a Symbiotic Relationship Between Scientists, Engineers, and Students

Science.gov (United States)

Chamberlin, Phillip C.

2011-01-01

Sounding rockets started in-situ space experimentation over 60 years ago with scientific experiments replacing warheads on captured V- 2 German rockets. Prior to this, and still today, suborbital platforms such as airplanes and high-altitude balloons have provided advantageous remote sensing observations advancing many areas of Earth and Space science. There is still a place for first-rate science in both stand-alone missions as well as providing complimentary measurements to the larger orbital missions. Along with the aforementioned science, the cost effectiveness and development times provided by sub-orbital platforms allows for perfect hands-on and first rate educational opportunities for undergraduate and graduate students. This talk will give examples and discuss the mutually beneficial opportunities that scientists and students obtain in development of suborbital missions. Also discussed will be how the next generation of space vehicles should help eliminate the number one obstacle to these programs - launch opportunities.

7 CFR 1944.664 - Housing preservation and replacement housing assistance.

Science.gov (United States)

2010-01-01

... 7 Agriculture 13 2010-01-01 2009-01-01 true Housing preservation and replacement housing...) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) HOUSING Housing...

Knee Replacement

Science.gov (United States)

Knee replacement is surgery for people with severe knee damage. Knee replacement can relieve pain and allow you to ... Your doctor may recommend it if you have knee pain and medicine and other treatments are not ...

Hardware replacements and software tools for digital control computers

International Nuclear Information System (INIS)

Walker, R.A.P.; Wang, B-C.; Fung, J.

1996-01-01

Technological obsolescence is an on-going challenge for all computer use. By design, and to some extent good fortune, AECL has had a good track record with respect to the march of obsolescence in CANDU digital control computer technology. Recognizing obsolescence as a fact of life, AECL has undertaken a program of supporting the digital control technology of existing CANDU plants. Other AECL groups are developing complete replacement systems for the digital control computers, and more advanced systems for the digital control computers of the future CANDU reactors. This paper presents the results of the efforts of AECL's DCC service support group to replace obsolete digital control computer and related components and to provide friendlier software technology related to the maintenance and use of digital control computers in CANDU. These efforts are expected to extend the current lifespan of existing digital control computers through their mandated life. This group applied two simple rules; the product, whether new or replacement should have a generic basis, and the products should be applicable to both existing CANDU plants and to 'repeat' plant designs built using current design guidelines. While some exceptions do apply, the rules have been met. The generic requirement dictates that the product should not be dependent on any brand technology, and should back-fit to and interface with any such technology which remains in the control design. The application requirement dictates that the product should have universal use and be user friendly to the greatest extent possible. Furthermore, both requirements were designed to anticipate user involvement, modifications and alternate user defined applications. The replacements for hardware components such as paper tape reader/punch, moving arm disk, contact scanner and Ramtek are discussed. The development of these hardware replacements coincide with the development of a gateway system for selected CANDU digital control

Service water system repair/replacement guidelines: Planning and implementation

International Nuclear Information System (INIS)

Frederick, G.J.; Gandy, D.W.; Peterson, A.G. Jr.; Findlan, S.J.

1993-11-01

Service water system failures have prompted concerns related to extended power plant operating life and plant availability. Selection and procurement of materials for repair or replacement of piping and components may be the most important factors in improving service water system reliability. The authors examined factors that contribute to reduced SWS reliability. The factors include material selection inadequacies, water treatment problems, operational/maintenance practices, fabrication procedures, environmental degradation mechanisms, and coating problems. The authors investigated material selection for replacement and repair, taking into account fabrication practices, environmental concerns, and cost comparisons of materials. They examined specific components such as piping, pumps, valves, and heat exchangers with regard to material selection and fabrication practice. Although proper material selection is essential in upgrading and maintaining the designed functions of a SWS, it is critical to address SWS repair/replacement activities with a systemwide approach. Degradation of materials in SWS applications are plant specific, depending on factors unique to each site such as geographic location, existing materials, operating procedures, and environment. All these characteristics must be addressed in making repair/replacement decisions. Criteria that must be integrated for successful long-term operation of SWS include the following: Materials selection (upgrade or in-kind replacement), Evaluation of root cause or nature of the failure mechanism, Scope of the repair/replacement activities, Material compatibility of the existing materials, Operational and maintenance procedures, Code or jurisdictional requirements, Economic considerations, Water treatment programs, System design improvements or modifications

Hormone Replacement and Strength Training Positively Influence Balance During Gait in Post-Menopausal Females: A Pilot Study

Science.gov (United States)

Perry, Stephen D.; Bombardier, Eric; Radtke, Alison; Tiidus, Peter M.

2005-01-01

This study examined the effects of hormone replacement combined with strength training on improving dynamic balance control in post-menopausal women. Thirty one participating post-menopausal women were divided into three groups (hormone replacement (HR), non-hormone replacement (NR) and control (CR) group). HR and NR groups were tested for muscle strength and balance control during gait, prior to training and following a six week lower body strength training program. Quadriceps muscle strength was evaluated as isokinetic peak torque (60°·sec-1) using a CYBEX NORM and balance control was evaluated by center of mass - base of support relationships and ground reaction forces during gait perturbations. Only the HR group showed significantly (p < 0.05) improved balance control during the initial phase of unexpected gait termination and single stance periods while walking across uneven terrain following training. The strength gains in the HR group tended to be greater than in the NR group over the six week training program, although neither group showed statistically significant increases. The CR group showed no significant differences between testing times. HR in post-menopausal females may enhance dynamic balance control when combined with a strength training program, even if no statistically significant gains in strength are achieved. Key Points This study provides evidence that even a short modest strength training program can enhance dynamic balance control in older adult females taking hormone replacement. If potential benefits of hormone replacement therapy extend to enhancing muscle strength then this would be important in designing optimal interventions for both strength and balance for this cohort. Future work should explore the influence of hormone replacement therapy on other dynamic balance or functional tasks. PMID:24501551

CORESAFE: A Formal Approach against Code Replacement Attacks on Cyber Physical Systems

Science.gov (United States)

2018-04-19

AFRL-AFOSR-JP-TR-2018-0035 CORESAFE:A Formal Approach against Code Replacement Attacks on Cyber Physical Systems Sandeep Shukla INDIAN INSTITUTE OF...Formal Approach against Code Replacement Attacks on Cyber Physical Systems 5a.  CONTRACT NUMBER 5b.  GRANT NUMBER FA2386-16-1-4099 5c.  PROGRAM ELEMENT...SUPPLEMENTARY NOTES 14.  ABSTRACT Industrial Control Systems (ICS) used in manufacturing, power generators and other critical infrastructure monitoring and

Nursing procedures during continuous renal replacement therapies: a national survey.

Science.gov (United States)

Ricci, Zaccaria; Benelli, Sonia; Barbarigo, Fabio; Cocozza, Giulia; Pettinelli, Noemi; Di Luca, Emanuela; Mettifogo, Mariangela; Toniolo, Andrea; Ronco, Claudio

2015-01-01

The current role of nurses in the management of critically ill patients needing continuous renal replacement therapies is clearly fundamental. The care of these complex patients is typically shared by critical care and dialysis nurses: their precise duties may vary from country to country. To clarify this issue we conducted a national-level survey at a recent Italian course on nursing practices during continuous renal replacement therapies. A total of 119 questionnaires were analysed. The participants, who were equally divided between critical care and dialysis nurses, came from 44 different hospitals and 35 Italian cities. Overall, 23% of participants answered that "the dialysis staff" were responsible for continuous renal replacement therapies in the Intensive Care Unit, while 39% answered "the critical care nurse", and 38% "a shared organization". Interestingly, less than the half of participants claimed specific continuous renal replacement therapies training was provided to employees before handling an acute dialysis machine. Finally, about 60% of participants had experience of extra-corporeal membrane oxygenation machines used in conjunction with continuous renal replacement therapies. Workload coordination and management of critically ill patients undergoing continuous renal replacement therapies in Italy is not standardized. At present, the duties of critical care and dialysis nurses vary significantly across the country. They frequently overlap or leave gaps in the assistance received by patients. The role of nurses involved in the care of continuous renal replacement therapies patients in Italy currently requires better organization, possibly starting with intensive standardized training and educational programs.

Flow boiling test of GDP replacement coolants

International Nuclear Information System (INIS)

Park, S.H.

1995-01-01

The tests were part of the CFC replacement program to identify and test alternate coolants to replace CFC-114 being used in the uranium enrichment plants at Paducah and Portsmouth. The coolants tested, C 4 F 10 and C 4 F 8 , were selected based on their compatibility with the uranium hexafluoride process gas and how well the boiling temperature and vapor pressure matched that of CFC-114. However, the heat of vaporization of both coolants is lower than that of CFC-114 requiring larger coolant mass flow than CFC-114 to remove the same amount of heat. The vapor pressure of these coolants is higher than CFC-114 within the cascade operational range, and each coolant can be used as a replacement coolant with some limitation at 3,300 hp operation. The results of the CFC-114/C 4 F 10 mixture tests show boiling heat transfer coefficient degraded to a minimum value with about 25% C 4 F 10 weight mixture in CFC-114 and the degree of degradation is about 20% from that of CFC-114 boiling heat transfer coefficient. This report consists of the final reports from Cudo Technologies, Ltd

Replacement Energy Cost Analysis Package (RECAP): User's guide. Revision 1

International Nuclear Information System (INIS)

VanKuiken, J.C.; Willing, D.L.

1994-07-01

A microcomputer program called the Replacement Energy Cost Analysis Package (RECAP) has been developed to assist the US Nuclear Regulatory Commission (NRC) in determining the replacement energy costs associated with short-term shutdowns or deratings of one or more nuclear reactors. The calculations are based on the seasonal, unit-specific cost estimates for 1993--1996 previously published in NRC Report NUREG/CR--4012, Vol. 3 (1992), for all 112 US reactors. Because the RECAP program is menu-driven, the user can define specific case studies in terms of such parameters as the units to be included, the length and timing of the shutdown or derating period, the unit capacity factors, and the reference year for reporting cost results. In addition to simultaneous shutdown cases, more complicated situations, such as overlapping shutdown periods or shutdowns that occur in different years, can be examined through the use of a present-worth calculation option

McGuire snubber elimination program

International Nuclear Information System (INIS)

Cloud, R.L.; Leung, J.S.M.; Taylor, W.H.; Morgan, R.L. Jr.

1993-01-01

An engineering program has been initiated at McGuire Nuclear Stations 1 and 2 to eliminate all existing snubbers. The elimination is achieved by replacing existing snubbers with limit stop pipe supports. The program establishes plant-wide modification procedures for one-to-one substitution under the 10 CFR 50.59 requirement. Nuclear Regulatory Commission (NRC) acceptance is based on the results of both comparison analyses and the hardware implementation of sample piping systems at McGuire nuclear stations. Experimental results obtained on shake table testing and from the NRC sponsored HDR research program are also used to formulate the technical basis and design procedures for plant-wide implementation of the snubber replacement effort. The overall program plan is for nearly 3,000 snubbers to be replaced in phases consistent with the plant scheduled outages. Duke Power estimates the program, when completed, will maintain ALARA, improve reliability, and reduce plant operating costs

Gate replacement at the Upper Lake Falls development

International Nuclear Information System (INIS)

Chen, C.T.; Locke, A.E.; Brown, E.R.

1998-01-01

Nova Scotia Power's integrated approach to dam safety was discussed. One of the two intake gates at Unit 1 of the Upper Falls Power Plant on the Mersey River was replaced in 1997 as part of the Utility's upgrading program. In the event of governor failure or turbine runaway, the new roller gate will allow operators to close the original sliding gate first under a more-or-less balanced head condition, and then to close the new roller gate under a full-flow condition. The planning, design and construction of the new roller gate is described. One of the two head gates of Unit 2 at the same station will be replaced in a similar fashion in the fall of 1998. 4 refs., 7 figs

Defining line replaceable units

NARCIS (Netherlands)

Parada Puig, J. E.; Basten, R. J I

2015-01-01

Defective capital assets may be quickly restored to their operational condition by replacing the item that has failed. The item that is replaced is called the Line Replaceable Unit (LRU), and the so-called LRU definition problem is the problem of deciding on which item to replace upon each type of

Optimizing model. 1. Insemination, replacement, seasonal production and cash flow.

NARCIS (Netherlands)

Delorenzo, M.A.; Spreen, T.H.; Bryan, G.R.; Beede, D.K.; Arendonk, van J.A.M.

1992-01-01

Dynamic programming to solve the Markov decision process problem of optimal insemination and replacement decisions was adapted to address large dairy herd management decision problems in the US. Expected net present values of cow states (151,200) were used to determine the optimal policy. States

Roadmap to MaRIE January 2015

Energy Technology Data Exchange (ETDEWEB)

Barnes, Cris William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2015-01-15

After the decision to end nuclear testing and the inception of the Stockpile Stewardship program, the condition of the stockpile was the primary mission driver. During the first two decades of stewardship, the primary program goal could be described as underwriting the Stockpile-to-Target Sequence (STS), the military requirements on the conditions the nuclear warheads needed to survive and still operate.

Preoperative Education for Hip and Knee Replacement: Never Stop Learning.

Science.gov (United States)

Edwards, Paul K; Mears, Simon C; Lowry Barnes, C

2017-09-01

Participation in alternative payment models has focused efforts to improve outcomes and patient satisfaction while also lowering cost for elective hip and knee replacement. The purpose of this review is to determine if preoperative education classes for elective hip and knee replacement achieve these goals. Recent literature demonstrates that patients who attend education classes prior to surgery have decreased anxiety, better post-operative pain control, more realistic expectations of surgery, and a better understanding of their surgery. As a result, comprehensive clinical pathways incorporating a preoperative education program for elective hip and knee replacement lead to lower hospital length of stay, higher home discharge, lower readmission, and improved cost. In summary, we report convincing evidence that preoperative education classes are an essential element to successful participation in alternative payment models such as the Bundle Payment Care Initiative.

Transcatheter aortic valve replacement

Science.gov (United States)

... gov/ency/article/007684.htm Transcatheter aortic valve replacement To use the sharing features on this page, please enable JavaScript. Transcatheter aortic valve replacement (TAVR) is surgery to replace the aortic valve. ...

7 CFR 3575.73 - Replacement of loss, theft, destruction, mutilation, or defacement of Loan Note Guarantee or...

Science.gov (United States)

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Replacement of loss, theft, destruction, mutilation... AGRICULTURE GENERAL Community Programs Guaranteed Loans § 3575.73 Replacement of loss, theft, destruction... circumstances of the loss, theft, or destruction of the Loan Note Guarantee or Assignment Guarantee Agreement...

Primary separator replacement for Bruce Unit 8 steam generators

International Nuclear Information System (INIS)

Roy, S.B.; Mewdell, C.G.; Schneider, W.G.

2000-01-01

During a scheduled maintenance outage of Bruce Unit 8 in 1998, it was discovered that the majority of the original primary steam separators were damaged in two steam generators. The Bruce B steam generators are equipped with GXP type primary cyclone separators of B and W supply. There were localized perforations in the upper part of the separators and large areas of generalized wall thinning. The degradation was indicative of a flow related erosion corrosion mechanism. Although the unit- restart was justified, it was obvious that corrective actions would be necessary because of the number of separators affected and the extent of the degradation. Repair was not considered to be a practical option and it was decided to replace the separators, as required, in Unit 8 steam generators during an advanced scheduled outage. GXP separators were selected for replacement to minimize the impact on steam generator operating characteristics and analysis. The material of construction was upgraded from the original carbon steel to stainless steel to maximize the assurance of full life. The replacement of the separators was a first of a kind operation not only for Ontario Power Generation and B and W but also for all CANDU plants. The paper describes the degradations observed and the assessments, the operating experience, manufacture and installation of the replacement separators. During routine inspection in 1998, many of the primary steam separators in two of steam generators at Bruce Nuclear Division B Unit 8 were observed to have through wall perforations. This paper describes assessment of this condition. It also discusses the manufacture and testing of replacement primary steam separators and the development and execution of the replacement separator installation program. (author)

Inspection and replacement of baffle assembly screws inside American reactor vessels

International Nuclear Information System (INIS)

Neal, K.; Chaumont, J.C.

1999-01-01

The baffle assembly inside the vessel of a 900 MWe reactor designed by Framatome, is made up of 44 plates fixed on 8 horizontal supports by a system of about 1000 screws. These plates undergo high neutron flux and the problem of screw cracking appeared at the end of the eighties in the first-generation reactors. The first operation on a large scale concerning the screws of a Westinghouse type reactor, was performed on the Tihange-1 power plant where Framatome controlled 960 screws and replaced 91. In 1997 as a consequence of the Belgian and French feedback experience, American plant operators launched a vast program of preventive actions: material analysis, inspection of baffle plate screws and replacement of defective screws. This program was held in cooperation with EPRI (electric power research institute) and under the control of NRC (nuclear regulatory commission). Framatome Technologies Inc (FTI) was in charge of the in-situ inspection and replacement of the screws. FTI designed special tools and equipment adapted to the 2-loop American reactors but the basis ideas were those applied on the Tihange reactor. The successful experience of FTI has allowed the firm to be commissioned for 6 2-loops American reactors. (A.C.)

Ankle replacement - discharge

Science.gov (United States)

... total - discharge; Total ankle arthroplasty - discharge; Endoprosthetic ankle replacement - discharge; Osteoarthritis - ankle ... You had an ankle replacement. Your surgeon removed and reshaped ... an artificial ankle joint. You received pain medicine and were ...

Patients Unicondylar Knee Replacement vs. Total Knee Replacement

OpenAIRE

Hedra Eskander

2017-01-01

The aim of this review article is to analyse the clinical effectiveness of total knee replacement (TKR) compared to unicondylar knee replacement (UKR) on patients. In terms of survival rates, revision rates and postoperative complications. The keywords used were: knee arthroplasty. Nearly three thousand articles were found on 25 August 2016. Of those, only twenty-five were selected and reviewed because they were strictly focused on the topic of this article. Compared with those who have TKR, ...

Artificial Disc Replacement

Science.gov (United States)

... Spondylolisthesis BLOG FIND A SPECIALIST Treatments Artificial Disc Replacement (ADR) Patient Education Committee Jamie Baisden The disc ... Disc An artificial disc (also called a disc replacement, disc prosthesis or spine arthroplasty device) is a ...

Product Platform Replacements

DEFF Research Database (Denmark)

Sköld, Martin; Karlsson, Christer

2012-01-01

. To shed light on this unexplored and growing managerial concern, the purpose of this explorative study is to identify operational challenges to management when product platforms are replaced. Design/methodology/approach – The study uses a longitudinal field-study approach. Two companies, Gamma and Omega...... replacement was chosen in each company. Findings – The study shows that platform replacements primarily challenge managers' existing knowledge about platform architectures. A distinction can be made between “width” and “height” in platform replacements, and it is crucial that managers observe this in order...... to challenge their existing knowledge about platform architectures. Issues on technologies, architectures, components and processes as well as on segments, applications and functions are identified. Practical implications – Practical implications are summarized and discussed in relation to a framework...

Point Lepreau refurbishment project programmable digital comparator (PDC) replacement for SDS1 and SDS2

International Nuclear Information System (INIS)

Ichiyen, N.M.; Chan, D.; Thompson, P.D.

2003-01-01

NB Power is tentatively planning to conduct an 18-month maintenance outage of the Point Lepreau Generating Station (PLGS) starting in April 2007. The scope of the outage was determined from the outcome of a two year study (Phase 1) involving a detailed condition assessment of the station which examined issues relating to ageing and obsolescence, along with a detailed review of Safety and Licensing issues associated with extended operation. In order to minimize schedule and regulatory risk for the Refurbishment project, pre-project work was initiated in early 2002. This program is called Phase 2 ESA (Early Start Activities). As part of the Phase 1 assessments it was concluded that replacement of the PDCs (Programmable Digital Comparators) for both shutdown systems was required in order to ensure operation of the plant for a further 25-30 years. Critical tasks were identified related to PDC replacement as part of the Phase 2 ESA program. This paper describes the activities that have taken place in the Phase 2 ESA program as well as the plan for future work for the PDC replacement for SDS 1 (Shutdown System Number One) and SDS2 (Shutdown System Number Two). (author)

Replacement

Directory of Open Access Journals (Sweden)

S. Radhakrishnan

2014-03-01

Full Text Available The fishmeal replaced with Spirulina platensis, Chlorella vulgaris and Azolla pinnata and the formulated diet fed to Macrobrachium rosenbergii postlarvae to assess the enhancement ability of non-enzymatic antioxidants (vitamin C and E, enzymatic antioxidants (superoxide dismutase (SOD and catalase (CAT and lipid peroxidation (LPx were analysed. In the present study, the S. platensis, C. vulgaris and A. pinnata inclusion diet fed groups had significant (P < 0.05 improvement in the levels of vitamins C and E in the hepatopancreas and muscle tissue. Among all the diets, the replacement materials in 50% incorporated feed fed groups showed better performance when compared with the control group in non-enzymatic antioxidant activity. The 50% fishmeal replacement (best performance diet fed groups taken for enzymatic antioxidant study, in SOD, CAT and LPx showed no significant increases when compared with the control group. Hence, the present results revealed that the formulated feed enhanced the vitamins C and E, the result of decreased level of enzymatic antioxidants (SOD, CAT and LPx revealed that these feeds are non-toxic and do not produce any stress to postlarvae. These ingredients can be used as an alternative protein source for sustainable Macrobrachium culture.

Study on Penetration Characteristics of Tungsten Cylindrical Penetrator

Energy Technology Data Exchange (ETDEWEB)

Jo, Jong Hyun; Lee, Young Shin; Kim, Jae Hoon [Chungnam Nat' l Univ., Daejeon (Korea, Republic of); Bae, Yong Woon [Agency for Defense Development, Daejeon (Korea, Republic of)

2013-09-15

The design of missile require extremely small warheads that must be highly efficient and lethal. The penetration characteristics of each penetrator and the total number of penetrators on the warhead are obvious key factors that influence warhead lethality. The design of the penetrator shape and size are directly related to the space and weight of the warhead. The design of the penetrator L/D was directly related to the space and weight of the warhead. L and D are the length and the diameter of the projectile, respectively. The AUTODYN-3a code was used to study the effect of penetrator penetration. The objective of numerical analysis was to determine the penetration characteristics of penetrator produced by hypervelocity impacts under different initial conditions such as initial velocity, obliquity angle and L/D of penetrator. The residual velocity and residual mass were decreased with increasing initial impact velocity under L/D{<=}4.

Plant Equipment Packages: Are they a Credible Deterrent to War

Science.gov (United States)

1990-12-01

PEP# TYPE CONTRACTOR/FACILITY NAME LOCATION 0112 WARHEAD CHAPARRAL M250 0112 WARHEAD HELFIRE MISSILE SYSTEM 0112 WARHEAD HE M225 LAP (DRAGON) 0112...0149 GRENADE SMK SCRN RP UKL8A3 F/ M250 LAUNCHER 0149 ROCKET 66MM INCEND TPA 4RD CLIP M74 0149 WARHEAD RKT 2.75IN SMK WP M156 W/FZ PD M427 0149 ROCKET...M25A2 (COMPLETE) 0149 GRENADE HAND/RIFLE SMK WP M34 W/F M206A2. 0149 GRENADE HAND RIOT CS ABC-M7A3 W/FZ M201AI 0149 GRENADE SMK SCRN RP UKL8A3 F/ M250

Capital Equipment Replacement Decisions

OpenAIRE

Batterham, Robert L.; Fraser, K.I.

1995-01-01

This paper reviews the literature on the optimal replacement of capital equipment, especially farm machinery. It also considers the influence of taxation and capital rationing on replacement decisions. It concludes that special taxation provisions such as accelerated depreciation and investment allowances are unlikely to greatly influence farmers' capital equipment replacement decisions in Australia.

Scenarios for exercising technical approaches to verified nuclear reductions

International Nuclear Information System (INIS)

Doyle, James

2010-01-01

Presidents Obama and Medvedev in April 2009 committed to a continuing process of step-by-step nuclear arms reductions beyond the new START treaty that was signed April 8, 2010 and to the eventual goal of a world free of nuclear weapons. In addition, the US Nuclear Posture review released April 6, 2010 commits the US to initiate a comprehensive national research and development program to support continued progress toward a world free of nuclear weapons, including expanded work on verification technologies and the development of transparency measures. It is impossible to predict the specific directions that US-RU nuclear arms reductions will take over the 5-10 years. Additional bilateral treaties could be reached requiring effective verification as indicated by statements made by the Obama administration. There could also be transparency agreements or other initiatives (unilateral, bilateral or multilateral) that require monitoring with a standard of verification lower than formal arms control, but still needing to establish confidence to domestic, bilateral and multilateral audiences that declared actions are implemented. The US Nuclear Posture Review and other statements give some indication of the kinds of actions and declarations that may need to be confirmed in a bilateral or multilateral setting. Several new elements of the nuclear arsenals could be directly limited. For example, it is likely that both strategic and nonstrategic nuclear warheads (deployed and in storage), warhead components, and aggregate stocks of such items could be accountable under a future treaty or transparency agreement. In addition, new initiatives or agreements may require the verified dismantlement of a certain number of nuclear warheads over a specified time period. Eventually procedures for confirming the elimination of nuclear warheads, components and fissile materials from military stocks will need to be established. This paper is intended to provide useful background information

Physiotherapy rehabilitation after total knee or hip replacement: an evidence-based analysis.

Science.gov (United States)

2005-01-01

The objective of this health technology policy analysis was to determine, where, how, and when physiotherapy services are best delivered to optimize functional outcomes for patients after they undergo primary (first-time) total hip replacement or total knee replacement, and to determine the Ontario-specific economic impact of the best delivery strategy. The objectives of the systematic review were as follows: To determine the effectiveness of inpatient physiotherapy after discharge from an acute care hospital compared with outpatient physiotherapy delivered in either a clinic-based or home-based setting for primary total joint replacement patientsTo determine the effectiveness of outpatient physiotherapy delivered by a physiotherapist in either a clinic-based or home-based setting in addition to a home exercise program compared with a home exercise program alone for primary total joint replacement patientsTo determine the effectiveness of preoperative exercise for people who are scheduled to receive primary total knee or hip replacement surgery Total hip replacements and total knee replacements are among the most commonly performed surgical procedures in Ontario. Physiotherapy rehabilitation after first-time total hip or knee replacement surgery is accepted as the standard and essential treatment. The aim is to maximize a person's functionality and independence and minimize complications such as hip dislocation (for hip replacements), wound infection, deep vein thrombosis, and pulmonary embolism. THE THERAPY: The physiotherapy rehabilitation routine has 4 components: therapeutic exercise, transfer training, gait training, and instruction in the activities of daily living. Physiotherapy rehabilitation for people who have had total joint replacement surgery varies in where, how, and when it is delivered. In Ontario, after discharge from an acute care hospital, people who have had a primary total knee or hip replacement may receive inpatient or outpatient

Replacing lactose from calf milk replacers : effects on digestion and post-absorptive metabolism

NARCIS (Netherlands)

Gilbert, M.S.

2015-01-01

Summary PhD thesis Myrthe S. Gilbert

Replacing lactose from calf milk replacers – Effects on digestion and post-absorptive metabolism

Veal calves are fed milk replacer (MR) and solid feed. The largest part of the energy provided to veal calves

Flued head replacement alternatives

International Nuclear Information System (INIS)

Smetters, J.L.

1987-01-01

This paper discusses flued head replacement options. Section 2 discusses complete flued head replacement with a design that eliminates the inaccessible welds. Section 3 discusses alternate flued head support designs that can drastically reduce flued head installation costs. Section 4 describes partial flued head replacement designs. Finally, Section 5 discusses flued head analysis methods. (orig./GL)

Point Lepreau Refurbishment Project. Programmable digital comparator (PDC) replacement for SDS1 and SDS2 - update 1

International Nuclear Information System (INIS)

Fraser, K.G.; Ichiyen, N.M.; Condor, A.E.; Thompson, P.D.

2005-01-01

NB Power is tentatively planning to conduct an 18-month maintenance outage of the Point Lepreau Generating Station starting in April 2008. The scope of the outage was determined from the outcome of a two year study (Phase 1) involving a detailed condition assessment of the station which examined issues relating to ageing and obsolescence, along with a detailed review of Safety and Licensing issues associated with extended operation. In order to minimize schedule and regulatory risk for the Refurbishment project, pre-project work was initiated in early 2002. This program is called Phase 2 ESA (Early Start Activities). As part of the Phase 1 assessments it was concluded that replacement of the Programmable Digital Comparators for both shutdown systems was required in order to ensure operation of the plant for a further 25-30 years. Critical tasks were identified related to PDC replacement as part of the Phase 2 ESA program. This paper describes the progress of the Phase 2 ESA program as well as the planned future (Phase 2) work for the PDC replacement for both shutdown systems. (author)

Technology management: a perspective on system support, procurement, and replacement planning.

Science.gov (United States)

Dickerson, M L; Jackson, M E

1992-01-01

The escalating costs associated with medical technology present a host of challenges for the hospital clinical engineering department. As service and support costs comprise ever larger portions of a system's life cycle cost, innovative management of service provider mix and mechanisms can provide substantial savings in operating expenses. In addition to full-service contracts, the use of demand service and independents has become commonplace. Medical equipment maintenance insurance programs provide yet another service alternative, combining the flexibility of demand service with the safety of a capped budget. These programs have gained acceptance among hospitals as their providers have become more focused on the healthcare market and its many needs. In view of the long-term cost impact surrounding technology procurement, the authors recommend that hospitals refine system evaluation methodologies and develop more comprehensive techniques directed at capital equipment replacement planning. One replacement planning approach, based on an estimation of system value changes, is described and illustrated using data collected through client consultations. Although the validity of this method has not been demonstrated, it represents a simplified approach to life cycle cost analysis and is intended to provide a standard method by which system replacement planning may be quantified. As a departure from system devaluation based solely on depreciation, this method estimates prospective system values derived from anticipated operations and maintenance costs, projected revenue, and the availability of new technology.

Refurbishment programs

International Nuclear Information System (INIS)

Irish, C.S.

2004-01-01

As nuclear plants age, equipment becomes obsolete, outdated or just simply unreliable. This puts a lot of emphasis on replacement of the subject equipment. This can be an expensive proposition for safety related equipment due to design changes, requalification charges and the cost of the new equipment, specifically when the original component is obsolete. The presentation will explain how comprehensive refurbishment programs on many different types of equipment can alleviate this situation. The refurbishment program is a systematic refurbishment of equipment to an as new condition by replacing all of the age sensitive components within the equipment. This is carried out on all of the same type of equipment in a scheduled program. For example the plant may to decide to refurbish all of their Lambda LME-24 power supplies, or all of their Bailey modules, or all of their Agastat DSC Series relays. Independent of the item the process is the same. Refurbish each piece of equipment to an as new condition by replacing all of the age sensitive equipment. The equipment is then returned to the client as safety related, existing qualification maintained and with a new service life/warranty. This is not a simple repair. It is a planned refurbishment to an as new condition of certain equipment types throughout the plant and then carried out from equipment piece to equipment piece. The refurbishment program may even include introducing new spares into the plant. This is normally performed by upgrading (dedicating for safety related use and refurbishing to an 'as new' condition) surplus equipment and using these equipment pieces in the rotation of the plant equipment to refurbish the entire population of a selected piece of equipment at the plant. This process can be performed on many equipment types including power supplies, circuit boards, modules, relays, motors, breakers, and many more. The refurbishment program greatly increases the reliability of the equipment without the

Implementing Replacement Cost Accounting

Science.gov (United States)

1976-12-01

cost accounting Clickener, John Ross Monterey, California. Naval Postgraduate School http://hdl.handle.net/10945/17810 Downloaded from NPS Archive...Calhoun IMPLEMENTING REPLACEMENT COST ACCOUNTING John Ross CHckener NAVAL POSTGRADUATE SCHOOL Monterey, California THESIS IMPLEMENTING REPLACEMENT COST ...Implementing Replacement Cost Accounting 7. AUTHORS John Ross Clickener READ INSTRUCTIONS BEFORE COMPLETING FORM 3. RECIPIENT’S CATALOG NUMBER 9. TYRE OF

Unmaking the bomb: Verifying limits on the stockpiles of nuclear weapons

Science.gov (United States)

Glaser, Alexander

2017-11-01

Verifying limits on the stockpiles of nuclear weapons may require the ability for international in-spectors to account for individual warheads, even when non-deployed, and to confirm the authenticity of nuclear warheads prior to dismantlement. These are fundamentally new challenges for nuclear verification, and they have been known for some time; unfortunately, due to a lack of sense of urgency, research in this area has not made substantial progress over the past 20 years. This chapter explores the central outstanding issues and offers a number of possible paths forward. In the case of confirming numerical limits, these in-clude innovative tagging techniques and approaches solely based on declarations using modern crypto-graphic escrow schemes; with regard to warhead confirmation, there has recently been increasing interest in developing fundamentally new measurement approaches where, in one form or another, sensitive infor-mation is not acquired in the first place. Overall, new international R&D efforts could more usefully focus on non-intrusive technologies and approaches, which may show more promise for early demonstration and adoption. In the meantime, while warhead dismantlements remain unverified, nuclear weapon states ought to begin to document warhead assembly, refurbishment, and dismantlement activities and movements of warheads and warhead components through the weapons complex in ways that international inspectors will find credible at a later time. Again, such a process could be enabled by modern cryptographic techniques such as blockchaining. Finally, and perhaps most importantly, it is important to recognize that the main reason for the complexity of technologies and approaches needed for nuclear disarmament verification is the requirement to protect information that nuclear weapon states consider sensitive. Ultimately, if information security concerns cannot be resolved to the satisfaction of all stakeholders, an alternative would be to "reveal the

Safety analysis program for steam generators replacement and power uprate at Tihange 2 nuclear power plant

International Nuclear Information System (INIS)

Delhaye, X.; Charlier, A.; Damas, Ph.; Druenne, H.; Mandy, C.; Parmentier, F.; Pirson, J.; Zhang, J.

2002-01-01

The Belgian Tihange 2 nuclear power plant went into commercial operation in 1983 producing a thermal power of 2785 MW. Since the commissioning of the plant the steam generators U-tubes have been affected by primary stress corrosion cracking. In order to avoid further degradation of the performance and an increase in repair costs, Electrabel, the owner of the plant, decided in 1997 to replace the 3 steam generators. This decision was supported by the feasibility study performed by Tractebel Energy Engineering which demonstrated that an increase of 10% of the initial power together with a fuel cycle length of 18 months was achieved. Tractebel Energy Engineering was entrusted by Electrabel as the owner's engineer to manage the project. This paper presents the role of Tractebel Energy Engineering in this project and the safety analysis program necessary to justify the new operation point and the fuel cycle extension to 18 months re-analysis of FSAR chapter 15 accidents and verification of the capacity of the safety and auxiliary systems. The FSAR chapter 15 accidents were reanalyzed jointly by Framatome and Tractebel Energy Engineering while the systems verifications were carried out by Tractebel Energy Engineering. (author)

Effects of a meal replacement system alone or in combination with phentermine on weight loss and food cravings.

Science.gov (United States)

Moldovan, Christina P; Weldon, Abby J; Daher, Noha S; Schneider, Louise E; Bellinger, Denise L; Berk, Lee S; Hermé, Alyson C; Aréchiga, Adam L; Davis, Willie L; Peters, Warren R

2016-11-01

To examine the effects of phentermine combined with a meal replacement program on weight loss and food cravings and to investigate the relationship between food cravings and weight loss. In a 12-week randomized, double-blind, placebo-controlled clinical trial, 77 adults with obesity received either phentermine or placebo. All participants were provided Medifast ® meal replacements, were instructed to follow the Take Shape for Life ® Optimal Weight 5&1 Plan for weight loss, and received lifestyle coaching in the Habits of Health program. The Food Craving Inventory and the General Food Cravings State and Trait Questionnaires were used to measure food cravings. The phentermine group lost 12.1% of baseline body weight compared with 8.8% in the placebo group. Cravings for all food groups decreased in both groups; however, there was a greater reduction in cravings for fats and sweets in the phentermine group compared with the placebo group. Percent weight loss correlated significantly with reduced total food cravings (r = 0.332, P = 0.009), cravings for sweets (r = 0.412, P meal replacement program and meal replacements alone significantly reduced body weight and food cravings; however, the addition of phentermine enhanced these effects. © 2016 The Obesity Society.

Pipe replacement in a water supply network: coordinated versus uncoordinated replacement and budget effects

NARCIS (Netherlands)

Dijk, van D.; Hendrix, E.M.T.

2016-01-01

Operators of underground water supply networks are challenged with pipe replacement
decisions, because pipes are subject to increased failure rates as they age and financial resources
are often limited.We study the optimal replacement time and optimal number of pipe replacements
such

Influence of Total Knee Arthroplasty on Gait Mechanics of the Replaced and Non-Replaced Limb During Stair Negotiation.

Science.gov (United States)

Standifird, Tyler W; Saxton, Arnold M; Coe, Dawn P; Cates, Harold E; Reinbolt, Jeffrey A; Zhang, Songning

2016-01-01

This study compared biomechanics during stair ascent in replaced and non-replaced limbs of total knee arthroplasty (TKA) patients with control limbs of healthy participants. Thirteen TKA patients and fifteen controls performed stair ascent. Replaced and non-replaced knees of TKA patients were less flexed at contact compared to controls. The loading response peak knee extension moment was greater in control and non-replaced knees compared with replaced. The push-off peak knee abduction moment was elevated in replaced limbs compared to controls. Loading and push-off peak hip abduction moments were greater in replaced limbs compared to controls. The push-off peak hip abduction moment was greater in non-replaced limbs compared to controls. Future rehabilitation protocols should consider the replaced knee and also the non-replaced knee and surrounding joints. Copyright © 2016 Elsevier Inc. All rights reserved.

Investigation of gamma-ray fingerprint identifying mechanism for the types of radiation sources

International Nuclear Information System (INIS)

Liu Suping; Wu Huailong; Gu Dangchang; Gong Jian; Hao Fanhua; Hu Guangchun

2002-01-01

Radiation fingerprints sometimes can be used to label and identify the radiation resources. For instance, in a future nuclear reduction treaty that requires verification of irreversible dismantling of reduced nuclear warheads, the radiation fingerprints of nuclear warheads are expected to play a key role in labelling and identifying the reduced warheads. It would promote the development of nuclear warheads deep-cuts verification technologies if authors start right now some investigations on the issues related to the radiation fingerprints. The author dedicated to the investigation of gamma-ray fingerprint identifying mechanism for the types of radiation resources. The purpose of the identifying mechanism investigation is to find a credible way to tell whether any two gamma-ray spectral fingerprints that are under comparison are radiated from the same resource. The authors created the spectrum pattern comparison (SPC) to study the comparability of the two radiation fingerprints. Guided by the principle of SPC, the authors programmed a software dedicated to identify the types of radiation resources. The efficiency of the software was tested by a series of experiments with some laboratory gamma-ray resources. The experiments were designed to look into the relations between comparability and radioactive statistics, and the relations between comparability and some measurement conditions such as real time, resource activity and background etc. Two main results can be drawn from the investigation: 1) it is quite feasible to use the concept of spectral comparability to answer the question whether any two gamma-ray fingerprints are identity or not; 2) the identifying mechanism can only identify the types of radiation resources, and cannot identify the individuals with the same type and small differences

Hip Replacement: MedlinePlus Health Topic

Science.gov (United States)

... invasive hip replacement (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Hip Replacement updates ... replacement - precautions Minimally invasive hip replacement Related Health Topics Hip Injuries and Disorders National Institutes of Health ...

Aorto-right atrial fistula after ascending aortic replacement or aortic value replacement

International Nuclear Information System (INIS)

Zhi Aihua; Dai Ruping; Jiang Shiliang; Lu Bin

2012-01-01

Objective: To evaluate the CT features of aorto-right atrial fistula after aortic valve replacement (AVR) or ascending aortic replacement. Methods: Eighty-seven patients with aortic-right atrial fistula underwent CT after operation. The CT features were retrospectively analyzed. Fistula was measured according to maximum width of the shunt. Results: Aorto-right atrial fistula was detected in 87 patients after aortic valve replacement or ascending aortic replacement by CT scan. Among them, 25 patients were diagnosed as mild aorto-right atrial fistula, 47 patients as moderate, and 15 patients as severe. Thirty-seven patients underwent follow-up CT.Among them, 10 patients with mild to moderate aorto-right atrial fistula were considered to have complete regression, 8 patients with mild aorto-right atrial fistula considered to have incomplete regression, 14 patients with mild to moderate aorto-right atrial fistula considered to have stable condition, and 5 patients with moderate aorto-right atrial fistula considered to have progression at the 3-month follow-up. Conclusion: CT is a useful tool for defining aorto-right atrial fistula after AVR or ascending aortic replacement and for evaluating it in follow-up. (authors)

The Effect of Modified "Aggression Replacement Training" Program on Self-efficacy of Adolescents with Insulin-dependent Diabetes

Directory of Open Access Journals (Sweden)

Seyed Reza Mazlom

2015-06-01

Full Text Available Background: Self-efficacy is a crucial factor in controlling adolescents with insulin-dependent diabetes mellitus (IDDM. Subsequently the negative behavioral reactions such as aggression adversely affect on self-efficacy. Therefore, interventions are essential to reduce the aggression and to improve the self- efficacy in these patients. Aim: To determine the efficacy of the modified "aggression replacement training" program on self-efficacy of adolescents with insulin-dependent diabetes. Methods: In this clinical trial, 70 adult subjects with IDDM who were referred to Parsian Diabetes clinic of Mashhad in 2014 were divided into two groups of intervention and control. The intervention program, including three aspects including: anger control training, social skills training and moral reasoning training was performed in five sessions, each 1.5-2 hours. A five-day interval was between the sessions and each group consisted of 8-10 individuals. The self-management standard questionnaire of “insulin-dependent diabetes management self-efficacy scale (IDMSE” was filled before the intervention and two months afterwards. Data were analyzed using SPSS version 11.5 with paired and Independent t-tests. Results: In this study, 38.5 and 61.5 percent of the subjects were boys and girls, respectively with total mean age of 15.9±2. The self-efficacy of the subjects before the intervention was not significantly different within the groups (p=0/57. Nevertheless in post-intervention assessment, the self-efficacy of the Intervention group significantly increased (49.0±11.1 compared to the control group (33.7±5.5 (p

Minimally invasive aortic valve replacement

DEFF Research Database (Denmark)

Foghsgaard, Signe; Schmidt, Thomas Andersen; Kjaergard, Henrik K

2009-01-01

In this descriptive prospective study, we evaluate the outcomes of surgery in 98 patients who were scheduled to undergo minimally invasive aortic valve replacement. These patients were compared with a group of 50 patients who underwent scheduled aortic valve replacement through a full sternotomy...... operations were completed as mini-sternotomies, 4 died later of noncardiac causes. The aortic cross-clamp and perfusion times were significantly different across all groups (P replacement...... is an excellent operation in selected patients, but its true advantages over conventional aortic valve replacement (other than a smaller scar) await evaluation by means of randomized clinical trial. The "extended mini-aortic valve replacement" operation, on the other hand, is a risky procedure that should...

Are output measurements always necessary after CT tube replacement?

Directory of Open Access Journals (Sweden)

Paul J Stauduhar

2014-03-01

Full Text Available Purpose: TX regulations and the ACR require that CT radiation output be measured within 30 days of major service. The most common major service is tube replacement. We hypothesized that historical QC data could be used instead to determine if output measurements are necessary, reducing the need for costly output measurements.Methods: We reviewed 66 records of tube replacements to determine with what frequency output falls outside specifications. We also conducted an experiment to verify that clinically significant output changes could be identified by comparing image noise in historical QC data with the same data after tube replacement. We used 30 days of historical QC data to establish a baseline noise level and 95% confidence interval (CI for individual noise measurements. To simulate output changes, we acquired phantom images with our QC protocol while manually changing output (mA. We acquired 10 images using the baseline output and 10 images at each different “output”. We evaluated individual images and subsets of images at each “output” to determine if the system was within the manufacturer’s specifications.Results: None of the 66 tube replacements resulted in an output change that exceeded specifications. Analysis of 30 days of historic QC data for our experimental system indicated a mean noise of 5.4 HU with 95% CI of 5.1 ‒ 5.7 HU. When using the mean noise of 10 images acquired at each of the varying outputs, we were able to identify, with 100% accuracy, images acquired at outputs outside manufacturer’s specifications.Conclusion: The results of our review of historical tube replacement data indicated the likelihood of output falling outside manufacturer’s specifications is low. Considering this, it is likely that by using QC data from programs required by regulation and the ACR physicists can reliably verify radiation output stability remotely instead of making physical measurements.--------------------Cite this article

Type II dehydroquinase: molecular replacement with many copies

International Nuclear Information System (INIS)

Stewart, Kirsty Anne; Robinson, David Alexander; Lapthorn, Adrian Jonathan

2007-01-01

The type II dehydroquinase enzyme is a symmetrical dodecameric protein which crystallizes in either high-symmetry cubic space groups or low-symmetry crystal systems with multiple copies in the asymmetric unit. Both systems have provided challenging examples for molecular replacement; for example, a triclinic crystal form has 16 dodecamers (192 monomers) in the unit cell. Three difficult examples are discussed and two are used as test cases to compare the performance of four commonly used molecular-replacement packages. Type II dehydroquinase is a small (150-amino-acid) protein which in solution packs together to form a dodecamer with 23 cubic symmetry. In crystals of this protein the symmetry of the biological unit can be coincident with the crystallographic symmetry, giving rise to cubic crystal forms with a single monomer in the asymmetric unit. In crystals where this is not the case, multiple copies of the monomer are present, giving rise to significant and often confusing noncrystallographic symmetry in low-symmetry crystal systems. These different crystal forms pose a variety of challenges for solution by molecular replacement. Three examples of structure solutions, including a highly unusual triclinic crystal form with 16 dodecamers (192 monomers) in the unit cell, are described. Four commonly used molecular-replacement packages are assessed against two of these examples, one of high symmetry and the other of low symmetry; this study highlights how program performance can vary significantly depending on the given problem. In addition, the final refined structure of the 16-dodecamer triclinic crystal form is analysed and shown not to be a superlattice structure, but rather an F-centred cubic crystal with frustrated crystallographic symmetry

Partial knee replacement - slideshow

Science.gov (United States)

... page: //medlineplus.gov/ency/presentations/100225.htm Partial knee replacement - series—Normal anatomy To use the sharing ... A.M. Editorial team. Related MedlinePlus Health Topics Knee Replacement A.D.A.M., Inc. is accredited ...

24 CFR 891.405 - Replacement reserve.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Replacement reserve. 891.405....405 Replacement reserve. (a) Establishment of reserve. The Owner shall establish and maintain a replacement reserve to aid in funding extraordinary maintenance and repair and replacement of capital items...

24 CFR 880.602 - Replacement reserve.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Replacement reserve. 880.602... Replacement reserve. (a) A replacement reserve must be established and maintained in an interest-bearing account to aid in funding extraordinary maintenance and repair and replacement of capital items. (1) Part...

24 CFR 891.855 - Replacement reserves.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Replacement reserves. 891.855... § 891.855 Replacement reserves. (a) The mixed-finance owner shall establish and maintain a replacement... the funds will be used to pay for capital replacement costs for the Section 202 or 811 supportive...

Application of the AMPLE cluster-and-truncate approach to NMR structures for molecular replacement

Energy Technology Data Exchange (ETDEWEB)

Bibby, Jaclyn [University of Liverpool, Liverpool L69 7ZB (United Kingdom); Keegan, Ronan M. [Research Complex at Harwell, STFC Rutherford Appleton Laboratory, Didcot OX11 0FA (United Kingdom); Mayans, Olga [University of Liverpool, Liverpool L69 7ZB (United Kingdom); Winn, Martyn D. [Science and Technology Facilities Council Daresbury Laboratory, Warrington WA4 4AD (United Kingdom); Rigden, Daniel J., E-mail: drigden@liv.ac.uk [University of Liverpool, Liverpool L69 7ZB (United Kingdom)

2013-11-01

Processing of NMR structures for molecular replacement by AMPLE works well. AMPLE is a program developed for clustering and truncating ab initio protein structure predictions into search models for molecular replacement. Here, it is shown that its core cluster-and-truncate methods also work well for processing NMR ensembles into search models. Rosetta remodelling helps to extend success to NMR structures bearing low sequence identity or high structural divergence from the target protein. Potential future routes to improved performance are considered and practical, general guidelines on using AMPLE are provided.

Dynamic optimization of maintenance and improvement planning for water main system: Periodic replacement approach

Energy Technology Data Exchange (ETDEWEB)

Kim, Jong Woo; Choi, Go Bong; Lee, Jong Min [Seoul National University, Seoul (Korea, Republic of); Suh, Jung Chul [Samchully Corporation, Seoul (Korea, Republic of)

2016-01-15

This paper proposes a Markov decision process (MDP) based approach to derive an optimal schedule of maintenance, rehabilitation and replacement of the water main system. The scheduling problem utilizes auxiliary information of a pipe such as the current state, cost, and deterioration model. The objective function and detailed algorithm of dynamic programming are modified to solve the periodic replacement problem. The optimal policy evaluated by the proposed algorithm is compared to several existing policies via Monte Carlo simulations. The proposed decision framework provides a systematic way to obtain an optimal policy.

Replacing stressful challenges with positive coping strategies: a resilience program for clinical placement learning.

Science.gov (United States)

Delany, C; Miller, K J; El-Ansary, D; Remedios, L; Hosseini, A; McLeod, S

2015-12-01

Clinical education is foundational to health professional training. However, it is also a time of increased stress for students. A student's perception of stressors and their capacity to effectively manage them is a legitimate concern for educators, because anxiety and decreased coping strategies can interfere with effective learning, clinical performance and capacity to care for patients. Resilience is emerging as a valuable construct to underpin positive coping strategies for learning and professional practice. We report the development and evaluation of a psycho-education resilience program designed to build practical skills-based resilience capacities in health science (physiotherapy) students. Six final year undergraduate physiotherapy students attended four action research sessions led by a clinical health psychologist. Resilience strategies drawn from cognitive behavioural therapy, and positive and performance psychology were introduced. Students identified personal learning stressors and their beliefs and responses. They chose specific resilience-based strategies to address them, and then reported their impact on learning performance and experiences. Thematic analysis of the audio-recorded and transcribed action research sessions, and students' de identified notes was conducted. Students' initial descriptions of stressors as 'problems' outside their control resulting in poor thinking and communication, low confidence and frustration, changed to a focus on how they managed and recognized learning challenges as normal or at least expected elements of the clinical learning environment. The research suggests that replacing stressful challenges with positive coping strategies offers a potentially powerful tool to build self-efficacy and cognitive control as well as greater self-awareness as a learner and future health practitioner.

25 CFR 700.53 - Dwelling, replacement.

Science.gov (United States)

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Dwelling, replacement. 700.53 Section 700.53 Indians THE... Policies and Instructions Definitions § 700.53 Dwelling, replacement. The term replacement dwelling means a dwelling selected by the head of a household as a replacement dwelling that meets the criteria of this...

Could wind replace nuclear?

International Nuclear Information System (INIS)

2017-01-01

This article aims at assessing the situation produced by a total replacement of nuclear energy by wind energy, while facing consumption demand at any moment, notably in December. The authors indicate the evolution of the French energy mix during December 2016, and the evolution of the rate between wind energy production and the sum of nuclear and wind energy production during the same month, and then give briefly some elements regarding necessary investments in wind energy to wholly replace nuclear energy. According to them, such a replacement would be ruinous

Molecular replacement then and now

International Nuclear Information System (INIS)

Scapin, Giovanna

2013-01-01

A brief overview, with examples, of the evolution of molecular-replacement methods and models over the past few years is presented. The ‘phase problem’ in crystallography results from the inability to directly measure the phases of individual diffracted X-ray waves. While intensities are directly measured during data collection, phases must be obtained by other means. Several phasing methods are available (MIR, SAR, MAD, SAD and MR) and they all rely on the premise that phase information can be obtained if the positions of marker atoms in the unknown crystal structure are known. This paper is dedicated to the most popular phasing method, molecular replacement (MR), and represents a personal overview of the development, use and requirements of the methodology. The first description of noncrystallographic symmetry as a tool for structure determination was explained by Rossmann and Blow [Rossmann & Blow (1962 ▶), Acta Cryst.15, 24–31]. The term ‘molecular replacement’ was introduced as the name of a book in which the early papers were collected and briefly reviewed [Rossmann (1972 ▶), The Molecular Replacement Method. New York: Gordon & Breach]. Several programs have evolved from the original concept to allow faster and more sophisticated searches, including six-dimensional searches and brute-force approaches. While careful selection of the resolution range for the search and the quality of the data will greatly influence the outcome, the correct choice of the search model is probably still the main criterion to guarantee success in solving a structure using MR. Two of the main parameters used to define the ‘best’ search model are sequence identity (25% or more) and structural similarity. Another parameter that may often be undervalued is the quality of the probe: there is clearly a relationship between the quality and the correctness of the chosen probe and its usefulness as a search model. Efforts should be made by all structural biologists to

Carbohydrates as Fat Replacers.

Science.gov (United States)

Peng, Xingyun; Yao, Yuan

2017-02-28

The overconsumption of dietary fat contributes to various chronic diseases, which encourages attempts to develop and consume low-fat foods. Simple fat reduction causes quality losses that impede the acceptance of foods. Fat replacers are utilized to minimize the quality deterioration after fat reduction or removal to achieve low-calorie, low-fat claims. In this review, the forms of fats and their functions in contributing to food textural and sensory qualities are discussed in various food systems. The connections between fat reduction and quality loss are described in order to clarify the rationales of fat replacement. Carbohydrate fat replacers usually have low calorie density and provide gelling, thickening, stabilizing, and other texture-modifying properties. In this review, carbohydrates, including starches, maltodextrins, polydextrose, gums, and fibers, are discussed with regard to their interactions with other components in foods as well as their performances as fat replacers in various systems.

Survivability of the Hardened Mobile Launcher When Attacked by a Hypothetical Rapidly Retargetable ICBM System.

Science.gov (United States)

1986-03-01

Aimpoints 22 Overviev 22 Random Movement of the RML 23 Computing Burst Locations and the HMIL’s Final Location 23 Selecting the HIMLs Speed. 29...described threat. The actual model used in this study is an MEASIC computer program . written and run on an Apple Macintosh computer . It is described in...mechanics of the computer program that models the warheads’ flight time sequence, it will be helpful to explain some of the elements of the sequence

The POP Program: the patient education advantage.

Science.gov (United States)

Claeys, M; Mosher, C; Reesman, D

1998-01-01

In 1992, a preoperative education program was developed for total joint replacement patients in a small community hospital. The goals of the program were to increase educational opportunities for the joint replacement patients, prepare patients for hospitalization, plan for discharge needs, and increase efficiency of the orthopaedic program. Since 1992, approximately 600 patients have attended the education program. Outcomes have included positive responses from patients regarding their preparedness for surgery, increased participation in their plan of care, coordinated discharge planning, decreased length of stay, and progression across the continuum of care. A multidisciplinary approach to preparing patients for surgery allows for a comprehensive and efficient education program. Marketing of successful programs can enhance an institution's competitive advantage and help ensure the hospital's viability in the current health care arena.

HORMONE REPLACEMENT AND STRENGTH TRAINING POSITIVELY INFLUENCE BALANCE DURING GAIT IN POST-MENOPAUSAL FEMALES: A PILOT STUDY

Directory of Open Access Journals (Sweden)

Stephen D. Perry

2005-12-01

Full Text Available This study examined the effects of hormone replacement combined with strength training on improving dynamic balance control in post-menopausal women. Thirty one participating post-menopausal women were divided into three groups (hormone replacement (HR, non-hormone replacement (NR and control (CR group. HR and NR groups were tested for muscle strength and balance control during gait, prior to training and following a six week lower body strength training program. Quadriceps muscle strength was evaluated as isokinetic peak torque (60°·sec-1 using a CYBEX NORM and balance control was evaluated by center of mass - base of support relationships and ground reaction forces during gait perturbations. Only the HR group showed significantly (p < 0.05 improved balance control during the initial phase of unexpected gait termination and single stance periods while walking across uneven terrain following training. The strength gains in the HR group tended to be greater than in the NR group over the six week training program, although neither group showed statistically significant increases. The CR group showed no significant differences between testing times. HR in post-menopausal females may enhance dynamic balance control when combined with a strength training program, even if no statistically significant gains in strength are achieved

Radiation Source Replacement Workshop

Energy Technology Data Exchange (ETDEWEB)

Griffin, Jeffrey W.; Moran, Traci L.; Bond, Leonard J.

2010-12-01

This report summarizes a Radiation Source Replacement Workshop in Houston Texas on October 27-28, 2010, which provided a forum for industry and researchers to exchange information and to discuss the issues relating to replacement of AmBe, and potentially other isotope sources used in well logging.

Optimal selection of Orbital Replacement Unit on-orbit spares - A Space Station system availability model

Science.gov (United States)

Schwaab, Douglas G.

1991-01-01

A mathematical programing model is presented to optimize the selection of Orbital Replacement Unit on-orbit spares for the Space Station. The model maximizes system availability under the constraints of logistics resupply-cargo weight and volume allocations.

Can photovoltaic replace nuclear?

International Nuclear Information System (INIS)

2017-01-01

As the French law on energy transition for a green growth predicts that one third of nuclear energy production is to be replaced by renewable energies (wind and solar) by 2025, and while the ADEME proposes a 100 per cent renewable scenario for 2050, this paper proposes a brief analysis of the replacement of nuclear energy by solar photovoltaic energy. It presents and discusses some characteristics of photovoltaic production: production level during a typical day for each month (a noticeable lower production in December), evolution of monthly production during a year, evolution of the rate between nuclear and photovoltaic production. A cost assessment is then proposed for energy storage and for energy production, and a minimum cost of replacement of nuclear by photovoltaic is assessed. The seasonal effect is outlined, as well as the latitude effect. Finally, the authors outline the huge cost of such a replacement, and consider that public support to new photovoltaic installations without an at least daily storage mean should be cancelled

RECAP, Replacement Energy Cost for Short-Term Reactor Plant Shut-Down

International Nuclear Information System (INIS)

VanKuiken, J.C.; Daun, C.J.; Jusko, M.J.

1995-01-01

1 - Description of program or function: RECAP (Replacement Energy Cost Analysis Package) determines the replacement energy costs associated with short-term shutdowns or de-ratings of one or more nuclear reactors. Replacement energy cost refers to the change in generating-system production cost that results from shutting down a reactor. The cost calculations are based on the seasonal, unit-specific cost estimates for 1988-1991 for all 117 nuclear electricity-generating units in the U.S. RECAP is menu-driven, allowing the user to define specific case studies in terms of parameters such as the units to be included, the length and timing of the shutdown or de-rating period, the unit capacity factors, and the reference year for reporting cost results. In addition to simultaneous shutdown cases, more complicated situations, such as overlapping shutdown periods or shutdowns that occur in different years, can be examined through use of a present-worth calculation option. 2 - Method of solution: The user selects a set of units for analysis, defines a shutdown (or de-rating) period, and specifies any planned maintenance outages, delays in unit start-ups, or changes in default capacity factors. The program then determines which seasonal cost numbers to apply, estimates total and daily costs, and makes the appropriate adjustments for multiple outages if they are encountered. The change in production cost is determined from the difference between the total variable costs (variable fuel cost, variable operation and maintenance cost, and purchased energy cost) when the reactor is available for generation and when it is not. Changes in reference-year dollars are based on gross national product (GNP) price deflators or on optional use inputs. Once RECAP has completed the initial cost estimates for a case study (or series of case studies), present-worth analysis can be conducted using different reference-year dollars and discount rates, as specified by the user. The program uses

Energy efficiency effect on the public street lighting by using LED light replacement and kwh-meter installation at DKI Jakarta Province, Indonesia

Science.gov (United States)

Sudarmono, Panggih; Deendarlianto; Widyaparaga, Adhika

2018-05-01

Public street lighting consumes large energy for the public interest, but many street lights still do not use energy-saving technologies. In 2014, Provincial Government of DKI Jakarta operated 179,305 units of street lights. Of the number of installed armature, 92 % of them or 166,441 units are HPS (High-Pressure Sodium) armatures which are inefficient. In 2016, the Provincial Government of DKI Jakarta cut down the energy used for street lighting, by implementing the programs of kWh-meter installation in every street lighting panel and use energy-saving lamps equipped with the smart system. The Provincial Government of DKI Jakarta is registered with 6,399 customer IDs in PLN (State Owned Electric Company), and gradually carried out the kWh Meter installation and changes to the contract. The program to use energy-saving lights done by replacing the HPS armature that is not energy efficient to LED armature which is known to be energy efficient. Until the end of 2016, the number of armatures that has been replaced was 89,417 units. The research results on 25 samples of PLN customer IDs and the replacement of 2,162 units armature, showed that the energy efficiency through kWh meter installation and armature replacement reduce the power consumption from 330,414 kWh to 71,278 kWh or by 78.43%. Generally, there was a decrease in the value of electricity bill compared to the before the replacement. The program of kWh-meter installations and replacement of the armature has a payback period of 2.66 years.

Effects of replacing lactose from milk replacer by glucose, fructose, or glycerol on energy partitioning in veal calves

NARCIS (Netherlands)

Gilbert, M. S.; Pantophlet, A. J.; van den Borne, J. J. G. C.; Hendriks, W. H.; Schols, H. A.; Gerrits, W. J. J.

Calf milk replacers contain 40 to 50% lactose. Fluctuating dairy prices are a major economic incentive to replace lactose from milk replacers by alternative energy sources. Our objective was, therefore, to determine the effects of replacement of lactose with glucose, fructose, or glycerol on energy

Technical challenges for dismantlement verification

International Nuclear Information System (INIS)

Olinger, C.T.; Stanbro, W.D.; Johnston, R.G.; Nakhleh, C.W.; Dreicer, J.S.

1997-01-01

In preparation for future nuclear arms reduction treaties, including any potential successor treaties to START I and II, the authors have been examining possible methods for bilateral warhead dismantlement verification. Warhead dismantlement verification raises significant challenges in the political, legal, and technical arenas. This discussion will focus on the technical issues raised by warhead arms controls. Technical complications arise from several sources. These will be discussed under the headings of warhead authentication, chain-of-custody, dismantlement verification, non-nuclear component tracking, component monitoring, and irreversibility. The authors will discuss possible technical options to address these challenges as applied to a generic dismantlement and disposition process, in the process identifying limitations and vulnerabilities. They expect that these considerations will play a large role in any future arms reduction effort and, therefore, should be addressed in a timely fashion

Aggression Replacement Training for Violent Young Men in a Forensic Psychiatric Outpatient Clinic

NARCIS (Netherlands)

Hornsveld, R.H.; Kraaimaat, F.W.; Muris, P.; Zwets, A.J.; Kanters, T.

2015-01-01

The effects of Aggression Replacement Training (ART) were explored in a group of Dutch violent young men aged 16 to 21 years, who were obliged by the court to follow a treatment program in a forensic psychiatric outpatient clinic. To evaluate the training, patients completed a set of self-report

A Cost Analysis of Kidney Replacement Therapy Options in Palestine

Directory of Open Access Journals (Sweden)

Mustafa Younis Ph.D.

2015-03-01

Full Text Available This study provides a cost analysis of kidney replacement therapy options in Palestine. It informs evidence-based resource allocation decisions for government-funded kidney disease services where transplant donors are limited, and some of the common modalities, i.e., peritoneal dialysis (PD and home hemodialysis (HD, are not widely available due to shortages of qualified staff, specialists, and centers to follow the patient cases, provide training, make home visits, or provide educational programs for patients. The average cost of kidney transplant was US$16 277 for the first year; the estimated cost of HD per patient averaged US$16 085 per year—nearly as much as a transplant. Consistent with prior literature and experience, while live, related kidney donors are scarce, we found that kidney transplant was more adequate and less expensive than HD. These results have direct resource allocation implications for government-funded kidney disease services under Palestinian Ministry of Health. Our findings strongly suggest that investing in sufficient qualified staff, equipment, and clinical infrastructure to replace HD services with transplantation whenever medically indicated and suitable kidney donors are available, as well as deploying PD programs and Home HD programs, will result in major overall cost savings. Our results provide a better understanding of the costs of kidney disease and will help to inform Ministry of Health and related policy makers as they develop short- and long-term strategies for the population, in terms of both cost savings and enhanced quality of life.

Delirium After Transcatheter Aortic Valve Replacement.

Science.gov (United States)

Giuseffi, Jennifer L; Borges, Nyal E; Boehm, Leanne M; Wang, Li; McPherson, John A; Fredi, Joseph L; Ahmad, Rashid M; Ely, E Wesley; Pandharipande, Pratik P

2017-07-01

Postoperative delirium is associated with increased mortality. Patients undergoing transcatheter aortic valve replacement are at risk for delirium because of comorbid conditions. To compare the incidence, odds, and mortality implications of delirium between patients undergoing transcatheter replacement and patients undergoing surgical replacement. The Richmond Agitation-Sedation Scale and the Confusion Assessment Method for the Intensive Care Unit were used to assess arousal level and delirium prospectively in all patients with severe aortic stenosis who had transcatheter or surgical aortic valve replacement at an academic medical center. Multivariable logistic regression was used to determine the relationship between procedure type and occurrence of delirium. Cox regression was used to assess the association between postoperative delirium and 6-month mortality. A total of 105 patients had transcatheter replacement and 121 had surgical replacement. Patients in the transcatheter group were older (median age, 81 vs 68 years; P replacement. Delirium is less likely to develop in the transcatheter group but is associated with higher mortality in both groups. ©2017 American Association of Critical-Care Nurses.

A Covert Disruptive Technology: Test and Development of the Corona Satellite

Science.gov (United States)

Peebles, Curtis

2008-01-01

The launching by the Soviet Union of the Sputnik satellite in 19457 was an impetuous to the United States. The Intercontinental ballistic Missile (ICBM) that launched the Earth's first satellite, could have been armed with a nuclear warhead, that could destroy an American city. The primary intelligence requirement that the US had was to determine the actual size of the Soviet missile program. To this end, a covert, high-risk photoreconnaissance satellite was developed. The code name of this program was "Corona." This article describes the trials and eventual successes of the Corona program.

Packaging and transportation of derived enriched uranium for the ''megatons to megawatts'' USA/Russia agreement

International Nuclear Information System (INIS)

Darrough, E.; Ewing, L.; Ravenscroft, N.

1998-01-01

In January 1998 the United States Enrichment Corporation (USEC) and Techsnabexport Co., Ltd (TENEX) of Russia celebrated the fourth anniversary of the signing of the 20-year contract between these two executive agents. USEC and TENEX are responsible for implementing the Government to-Government agreement between the United States and the Russian Federation for the purchase of uranium derived from dismantled nuclear weapons from the former Soviet Union. This program, entitled 'Megatons to Megawatts', is the first time nuclear warheads have been turned into fuel as well as the first time a commercial contract has been used to implement such a program. As of the fourth anniversary, the equivalent of almost 1,200 nuclear warheads had been converted to fuel. USEC is responsible for making all of the arrangements to transport the Russian LEU derived from HEU--hence the term, derived enriched uranium (DEU)--from St Petersburg. Russia to the USEC plant near portsmouth, Ohio. Edlow International Company is working with USEC to implement the shipping campaign and is responsible for coordination of the port delivery within Russia, as well. The organization responsible for these shipments within Russia is IZOTOP. While the program has been a major new responsibility for USEC, the early years of the program prepared all parties for the future challenges such as increased numbers of shipments, additional originating sites in Russia and witnessing requirements in Russia. (authors)

Startup program after SGR and power increase

International Nuclear Information System (INIS)

Krajnc, B.; Dudas, M.; Spiler, J.; Novsak, M.

2000-01-01

NPP Krsko replaced steam generators during the outage 2000. Parallel with the steam generator replacement all required systems modifications to accommodate new steam generators into the existing plant (upper feed,..) and support plant power increase of 6.3%, have been implemented. During the years 1997 - 2000 all the required licensing, technical analyses and systems verifications to support such plant changes have been completed. One of the activities within this effort was also the preparation of a detailed Plant Startup Program, which was subject of licensing review and approval process. An integrated plant startup program was then developed based on the plant startup test program, performed regularly during plant startup after refueling and above-mentioned Plant Startup Program. These additional tests defined by the Startup Test Program have been required due to new steam generators, steam generator replacement and related modifications, and power increase from previous 1882 MWt to 2000 MWt. During the preparation period, a startup team was established and procedures were written. All procedures sensitive to the operation were validated on the plant specific simulator. This paper presents more about the Startup Test Program, analysis of its implementation, the results of some key tests as well as the lessons learned. (author)

Meal replacements as a weight loss tool in a population with severe mental illness.

Science.gov (United States)

Gelberg, Hollie A; Kwan, Crystal L; Mena, Shirley J; Erickson, Zachary D; Baker, Matthew R; Chamberlin, Valery; Nguyen, Charles; Rosen, Jennifer A; Shah, Chandresh; Ames, Donna

2015-12-01

Weight gain and worsening metabolic parameters are often side effects of antipsychotic medications used by individuals with severe mental illness. To address this, a randomized, controlled research study of a behavioral weight management program for individuals with severe mental illness was undertaken to assess its efficacy. Patients unable to meet weight loss goals during the first portion of the year-long study were given the option of using meal replacement shakes in an effort to assist with weight loss. Specific requirements for use of meal replacement shakes were specified in the study protocol; only five patients were able to use the shakes in accordance with the protocol and lose weight while improving metabolic parameters. Case studies of two subjects are presented, illustrating the challenges and obstacles they faced, as well as their successes. Taking responsibility for their own weight loss, remaining motivated through the end of the study, and incorporating the meal replacement shakes into a daily routine were factors found in common with these patients. Use of meal replacements shakes with this population may be effective. Published by Elsevier Ltd.

Feeder replacement tooling and processes

International Nuclear Information System (INIS)

Mallozzi, R.; Goslin, R.; Pink, D.; Askari, A.

2008-01-01

Primary heat transport system feeder integrity has become a concern at some CANDU nuclear plants as a result of thinning caused by flow accelerated corrosion (FAC). Feeder inspections are indicating that life-limiting wall thinning can occur in the region between the Grayloc hub weld and second elbow of some outlet feeders. In some cases it has become necessary to replace thinned sections of affected feeders to restore feeder integrity to planned end of life. Atomic Energy of Canada Limited (AECL) and Babcock and Wilcox Canada Ltd. (B and W) have developed a new capability for replacement of single feeders at any location on the reactor face without impacting or interrupting operation of neighbouring feeders. This new capability consists of deploying trained crews with specialized tools and procedures for feeder replacements during planned outages. As may be expected, performing single feeder replacement in the congested working environment of an operational CANDU reactor face involves overcoming many challenges with respect to access to feeders, available clearances for tooling, and tooling operation and performance. This paper describes some of the challenges encountered during single feeder replacements and actions being taken by AECL and B and W to promote continuous improvement of feeder replacement tooling and processes and ensure well-executed outages. (author)

Optimization on replacement period of plant equipment

International Nuclear Information System (INIS)

Kasai, Masao; Asano, Hiromi

2002-01-01

Optimization of the replacement period of plant equipment is one of the main items to rationalize the activities on plant maintenance. There are several models to replace the equipment and the formulations for optimizing the replacement period are different among these models. In this study, we calculated the optimum replacement periods for some equipment parts based on the replacement models and found that the optimum solutions are not so largely differ from the replacement models as far as the replacement period is not so large. So we will be able to use the most usable model especially in the early phase of rationalization on plant maintenance, since there are large uncertainties in data for optimization. (author)

Defense Advanced Research Projects Agency Fiscal Year 1982 Research & Development Program. Summary Statement by Dr. Robert R. Fossum, Director Before the Research & Development Subcommittee of the House Armed Services Committee

Science.gov (United States)

1981-03-12

progressive burning rocket motors , and advanced warheads in a low-cost, high-performance, day/night, fire-and-forget missile that would be a...for advanced homopolar generators (energy storage systems) were completed in FY 1979; detailed engineering drawings of the generators were completed

XTAL system of crystallographic programs: programmer's manual

International Nuclear Information System (INIS)

Hall, S.R.; Stewart, J.M.; Norden, A.P.; Munn, R.J.; Freer, S.T.

1980-02-01

This document establishes the basis for collaborative writing of transportable computer programs for x-ray crystallography. The concepts and general-purpose utility subroutines described here can be readily adapted to other scientific calculations. The complete system of crystallographic programs and subroutines is called XTAL and replaces the XRAY (6,7,8) system of programs. The coding language for the XTAL system is RATMAC (5). The XTAL system of programs contains routines for controlling execution of application programs. In this sense it forms a suboperating system that presents the same computational environment to the user and programmer irrespective of the operating system in use at a particular installation. These control routines replace all FORTRAN I/O code, supply character reading and writing, supply binary file reading and writing, serve as a support library for applications programs, and provide for interprogram communication

TEACHING ALGORITHMIZATION AND PROGRAMMING USING PYTHON LANGUAGE

Directory of Open Access Journals (Sweden)

M. Lvov

2014-07-01

Full Text Available The article describes requirements to educational programming languages and considers the use of Python as the first programming language. The issues of introduction of this programming language into teaching and replacing Pascal by Python are examined. The advantages of such approach are regarded. The comparison of popular programming languages is represented from the point of view of their convenience of use for teaching algorithmization and programming. Python supports lots of programming paradigms: structural, object-oriented, functional, imperative and aspect-oriented, and learning can be started without any preparation. There is one more advantage of the language: all algorithms are written easily and structurally in Python. Therefore, due to all mentioned above, it is possible to affirm that Python pretends to become a decent replacement for educational programming language PASCAL both at schools and on the first courses of higher education establishments.

Integrable RCS as a Proposed Replacement for Fermilab Booster

Energy Technology Data Exchange (ETDEWEB)

Eldred, Jeffrey [Fermilab; Valishev, Alexander [Fermilab

2017-03-07

Integrable optics is an innovation in particle accelerator design that potentially enables a greater betatron tune spread and damps collective instabilities. An integrable rapid-cycling synchrotron (RCS) would be an effective replacement for the Fermilab Booster, as part of a plan to reach multi-MW beam power at 120 GeV for the Fermilab high-energy neutrino program. We provide an example integrable lattice with features of a modern RCS - dispersion-free drifts, low momentum compaction factor, superperiodicity, chromaticity correction, bounded beta functions, and separate-function magnets.

Diagenetic replacement of Micas by Carbonates

NARCIS (Netherlands)

Oele, E.

1961-01-01

In the Ordovician sandstones of the Cantabrian Mountains a replacement of the micas by carbonate minerals could be observed. The absence of metamorphic minerals suggests a diagenetic replacement. This is supported by the finding of the same type of replacement in some undisturbed Pliocene sediments

Cognitive Development in Infantile-Onset Pompe Disease Under Very Early Enzyme Replacement Therapy.

Science.gov (United States)

Lai, Chih-Jou; Hsu, Ting-Rong; Yang, Chia-Feng; Chen, Shyi-Jou; Chuang, Ya-Chin; Niu, Dau-Ming

2016-12-01

Most patients with infantile-onset Pompe disease die in early infancy before beginning enzyme replacement therapy, which has made it difficult to evaluate the impact of Pompe disease on cognitive development. Patients with infantile-onset Pompe disease can survive with enzyme replacement therapy, and physicians can evaluate cognitive development in these patients. We established an effective newborn screening program with quick clinical diagnostic criteria. Cognitive and motor development were evaluated using the Bayley Scales of Infant and Toddler Development-Third Edition at 6, 12, and 24 months of age. The patients who were treated very early demonstrate normal cognitive development with no significant change in cognition during this period (P = .18 > .05). The cognitive development was positively correlated with motor development (r = 0.533, P = .011). The results indicated that very early enzyme replacement therapy could protect cognitive development in patients with infantile-onset Pompe disease up to 24 months of age. © The Author(s) 2016.

47 CFR 13.17 - Replacement license.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Replacement license. 13.17 Section 13.17 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL RADIO OPERATORS General § 13.17 Replacement... request a replacement. The application must be accompanied by the required fee and submitted to the...

24 CFR 891.605 - Replacement reserve.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Replacement reserve. 891.605... 8 Assistance § 891.605 Replacement reserve. (a) Establishment of reserve. The Borrower shall establish and maintain a replacement reserve to aid in funding extraordinary maintenance, and repair and...

7 CFR 3015.167 - Replacement of equipment.

Science.gov (United States)

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Replacement of equipment. 3015.167 Section 3015.167..., DEPARTMENT OF AGRICULTURE UNIFORM FEDERAL ASSISTANCE REGULATIONS Property § 3015.167 Replacement of equipment. (a) If needed, equipment may be exchanged for replacement equipment. Replacement of equipment may be...

International examples of steam generator replacement

International Nuclear Information System (INIS)

Wiechmann, K.

1993-01-01

Since 1979-1980 a total of twelve nuclear power plants world-wide have had their steam generators replaced. The replacement of the Combustion steam generators in the Millstone-2 plant in the United States was completed very recently. Steam generator replacement activities are going on at present in four plants. In North Anna, the steam generators have been under replacement since January 1990. In Japan, preparations have been started for Genkai-1. Since January 1992, the two projects in Beznau-1, Switzerland, and Doel-3, Belgium, have bee planned and executed in parallel. Why steam generator replacement? There are a number of defect mechanisms which give rise to the need for early steam generator replacement. One of the main reasons is the use of Inconel-600 as material for the heating tubes. Steam generator heating tubes made of Inconel-600 have been known to exhibit their first defects due to stress corrosion cracking after less than one year of operation. (orig.) [de

Investigation of gamma-ray fingerprint identifying mechanism for the types of radiation sources

CERN Document Server

Liu Su Ping; Gu Dang Chang; Gong-Jian; Hao Fan Hua; Hu Guang Chun

2002-01-01

Radiation fingerprints sometimes can be used to label and identify the radiation resources. For instance, in a future nuclear reduction treaty that requires verification of irreversible dismantling of reduced nuclear warheads, the radiation fingerprints of nuclear warheads are expected to play a key role in labelling and identifying the reduced warheads. It would promote the development of nuclear warheads deep-cuts verification technologies if authors start right now some investigations on the issues related to the radiation fingerprints. The author dedicated to the investigation of gamma-ray fingerprint identifying mechanism for the types of radiation resources. The purpose of the identifying mechanism investigation is to find a credible way to tell whether any two gamma-ray spectral fingerprints that are under comparison are radiated from the same resource. The authors created the spectrum pattern comparison (SPC) to study the comparability of the two radiation fingerprints. Guided by the principle of SPC,...

Long-life slab replacement concrete.

Science.gov (United States)

2015-03-01

This research was initiated following reports of high incidence of cracking on FDOT concrete pavement replacement : slab projects. Field slabs were instrumented for data acquisition from high-early-strength concrete pavement : replacement slabs place...

Nuclear reactor fuel replacement system

International Nuclear Information System (INIS)

Kayano, Hiroyuki; Joge, Toshio.

1976-01-01

Object: To permit the direction in which a fuel replacement unit is moving to be monitored by the operator. Structure: When a fuel replacement unit approaches an intermediate goal position preset in the path of movement, renewal of data display on a goal position indicator is made every time the goal position is changed. With this renewal, the prevailing direction of movement of the fuel replacement unit can be monitored by the operator. When the control of movement is initiated, the co-ordinates of the intermediate goal point A are displayed on a goal position indicator. When the replacement unit reaches point A, the co-ordinates of the next intermediate point B are displayed, and upon reaching point B the co-ordinates of the (last) goal point C are displayed. (Nakamura, S.)

Defense programs business practices re-engineering QFD exercise

International Nuclear Information System (INIS)

Murray, C.; Halbleib, L.

1996-03-01

The end of the cold war has resulted in many changes for the Nuclear Weapons Complex (NWC). We now work in a smaller complex, with reduced resources, a smaller stockpile, and no new phase 3 weapons development programs. This new environment demands that we re-evaluate the way we design and produce nuclear weapons. The Defense Program (DP) Business Practices Re-engineering activity was initiated to improve the design and production efficiency of the DP Sector. The activity had six goals: (1) to identify DP business practices that are exercised by the Product Realization Process (PRP); (2) to determine the impact (positive, negative, or none) of these practices on defined, prioritized customer criteria; (3) to identify business practices that are candidates for elimination or re-engineering; (4) to select two or three business practices for re-engineering; (5) to re-engineer the selected business practices; and (6) to exercise the re-engineered practices on three pilot development projects. Business practices include technical and well as administrative procedures that are exercised by the PRP. A QFD exercise was performed to address (1)-(4). The customer that identified, defined, and prioritized the criteria to rate the business practices was the Block Change Advisory Group. Five criteria were identified: cycle time, flexibility, cost, product performance/quality, and best practices. Forty-nine business practices were identified and rated per the criteria. From this analysis, the group made preliminary recommendations as to which practices would be addressed in the re-engineering activity. Sixteen practices will be addressed in the re-engineering activity. These practices will then be piloted on three projects: (1) the Electronic Component Assembly (ECA)/Radar Project, (2) the B61 Mod 11, and (3) Warhead Protection Program (WPP)

Functional Programming in R

DEFF Research Database (Denmark)

Mailund, Thomas

Master functions and discover how to write functional programs in R. In this book, you'll make your functions pure by avoiding side-effects; you’ll write functions that manipulate other functions, and you’ll construct complex functions using simpler functions as building blocks. In Functional...... Programming in R, you’ll see how we can replace loops, which can have side-effects, with recursive functions that can more easily avoid them. In addition, the book covers why you shouldn't use recursion when loops are more efficient and how you can get the best of both worlds. Functional programming...... functions by combining simpler functions. You will: Write functions in R including infix operators and replacement functions Create higher order functions Pass functions to other functions and start using functions as data you can manipulate Use Filer, Map and Reduce functions to express the intent behind...

31 CFR 361.8 - Claim for replacement.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Claim for replacement. 361.8 Section... § 361.8 Claim for replacement. Claim for replacement shall be made in writing to the Secretary, to the..., Parkersburg, WV 26106-1328. The claim, accompanied by a recommendation regarding the manner of replacement...

Solving structures of protein complexes by molecular replacement with Phaser

International Nuclear Information System (INIS)

McCoy, Airlie J.

2006-01-01

Four case studies in using maximum-likelihood molecular replacement, as implemented in the program Phaser, to solve structures of protein complexes are described. Molecular replacement (MR) generally becomes more difficult as the number of components in the asymmetric unit requiring separate MR models (i.e. the dimensionality of the search) increases. When the proportion of the total scattering contributed by each search component is small, the signal in the search for each component in isolation is weak or non-existent. Maximum-likelihood MR functions enable complex asymmetric units to be built up from individual components with a ‘tree search with pruning’ approach. This method, as implemented in the automated search procedure of the program Phaser, has been very successful in solving many previously intractable MR problems. However, there are a number of cases in which the automated search procedure of Phaser is suboptimal or encounters difficulties. These include cases where there are a large number of copies of the same component in the asymmetric unit or where the components of the asymmetric unit have greatly varying B factors. Two case studies are presented to illustrate how Phaser can be used to best advantage in the standard ‘automated MR’ mode and two case studies are used to show how to modify the automated search strategy for problematic cases

Effect of growth hormone replacement therapy on pituitary hormone secretion and hormone replacement therapies in GHD adults

DEFF Research Database (Denmark)

Hubina, Erika; Mersebach, Henriette; Rasmussen, Ase Krogh

2004-01-01

We tested the impact of commencement of GH replacement therapy in GH-deficient (GHD) adults on the circulating levels of other anterior pituitary and peripheral hormones and the need for re-evaluation of other hormone replacement therapies, especially the need for dose changes.......We tested the impact of commencement of GH replacement therapy in GH-deficient (GHD) adults on the circulating levels of other anterior pituitary and peripheral hormones and the need for re-evaluation of other hormone replacement therapies, especially the need for dose changes....

24 CFR 891.745 - Replacement reserve.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Replacement reserve. 891.745... and Individuals-Section 162 Assistance § 891.745 Replacement reserve. The general requirements for the replacement reserve are provided in § 891.605. For projects funded under §§ 891.655 through 891.790, the...

A Debate over the Teaching of a Legacy Programming Language in an Information Technology (IT) Program

Science.gov (United States)

Ali, Azad; Smith, David

2014-01-01

This paper presents a debate between two faculty members regarding the teaching of the legacy programming course (COBOL) in a Computer Science (CS) program. Among the two faculty members, one calls for the continuation of teaching this language and the other calls for replacing it with another modern language. Although CS programs are notorious…

Optimization of station battery replacement

International Nuclear Information System (INIS)

Jancauskas, J.R.; Shook, D.A.

1994-01-01

During a loss of ac power at a nuclear generating station (including diesel generators), batteries provide the source of power which is required to operate safety-related components. Because traditional lead-acid batteries have a qualified life of 20 years, the batteries must be replaced a minimum of once during a station's lifetime, twice if license extension is pursued, and more often depending on actual in-service dates and the results of surveillance tests. Replacement of batteries often occurs prior to 20 years as a result of systems changes caused by factors such as Station Blackout Regulations, control system upgrades, incremental load growth, and changes in the operating times of existing equipment. Many of these replacement decisions are based on the predictive capabilities of manual design basis calculations. The inherent conservatism of manual calculations may result in battery replacements occurring before actually required. Computerized analysis of batteries can aid in optimizing the timing of replacements as well as in interpreting service test data. Computerized analysis also provides large benefits in maintaining the as-configured load profile and corresponding design margins, while also providing the capability of quickly analyze proposed modifications and response to internal and external audits

Prolonged Intermittent Renal Replacement Therapy.

Science.gov (United States)

Edrees, Fahad; Li, Tingting; Vijayan, Anitha

2016-05-01

Prolonged intermittent renal replacement therapy (PIRRT) is becoming an increasingly popular alternative to continuous renal replacement therapy in critically ill patients with acute kidney injury. There are significant practice variations in the provision of PIRRT across institutions, with respect to prescription, technology, and delivery of therapy. Clinical trials have generally demonstrated that PIRRT is non-inferior to continuous renal replacement therapy regarding patient outcomes. PIRRT offers cost-effective renal replacement therapy along with other advantages such as early patient mobilization and decreased nursing time. However, due to lack of standardization of the procedure, PIRRT still poses significant challenges, especially pertaining to appropriate drug dosing. Future guidelines and clinical trials should work toward developing consensus definitions for PIRRT and ensure optimal delivery of therapy. Copyright © 2016 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

10 CFR 830 Major Modification Determination for Emergency Firewater Injection System Replacement

International Nuclear Information System (INIS)

Duckwitz, Noel

2011-01-01

The continued safe and reliable operation of the ATR is critical to the Department of Energy (DOE) Office of Nuclear Energy (NE) mission. While ATR is safely fulfilling current mission requirements, a variety of aging and obsolescence issues challenge ATR engineering and maintenance personnel's capability to sustain ATR over the long term. First documented in a series of independent assessments, beginning with an OA Environmental Safety and Health Assessment conducted in 2003, the issues were validated in a detailed Material Condition Assessment (MCA) conducted as a part of the ATR Life Extension Program in 2007. Accordingly, near term replacement of aging and obsolescent original ATR equipment has become important to ensure ATR capability in support of NE's long term national missions. To that end, a mission needs statement has been prepared for a non-major system acquisition which is comprised of three interdependent sub-projects. The first project will replace the existent diesel-electrical bus (E-3), switchgear, and the fifty year old antiquated marine diesels with commercial power that is backed with safety-related emergency diesel generators (EDGs), switchgear, and uninterruptible power supply. The second project will replace the four, obsolete, original primary coolant pumps and motors. The third project, the subject of this major modification determination, will replace the current emergency firewater injection system (EFIS). The replacement water injection system will function as the primary emergency water injection system with the EFIS being retained as a defense-in-depth backup. Completion of this and the two other age-related projects (replacement of the ATR diesel bus (E-3) and switchgear and replacement of the existent aged primary coolant pumps and motors) will resolve major age-related operational issues plus make a significant contribution in sustaining the ATR safety and reliability profile. The major modification criteria evaluation of the

20 CFR 416.110 - Purpose of program.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Purpose of program. 416.110 Section 416.110... income program replaces the financial assistance programs for the aged, blind, and disabled in the 50... the program: (a) Objective tests. The law provides that payments are to be made to aged, blind, and...

Short communication: Absorption of protein and immunoglobulin g in calves fed a colostrum replacer.

Science.gov (United States)

Smith, G W; Foster, D M

2007-06-01

A well-managed colostrum program on farms is the most important step in reducing disease in neonatal calves. In the last few years, colostrum replacers have increased in popularity and are designed to be an alternative to colostrum on farms that have poor colostrum quality, limited colostrum reserves, or to break the cycle of transmission for certain infectious diseases. However, it is important to make sure these products are effective and are capable of providing adequate serum immunoglobulin concentrations. The objective of this study was to evaluate the efficacy of a commercially available colostrum replacer product in dairy calves. Holstein calves from a single dairy were randomly assigned to 1 of 3 groups at birth. Group 1 (n = 21) calves were given 4 quarts of colostrum via esophageal feeder within 3 h of birth and served as the control group for this study. Group 2 (n = 21) received 2 packages of a colostrum replacer product, and group 3 (n = 21) received 3 packages of the colostrum replacer product within 3 h of birth. Blood samples from all calves were collected 24 h after colostrum administration and analyzed for serum total protein and IgG concentrations. Calves fed fresh colostrum had significantly higher serum total protein levels and IgG concentrations compared with calves fed the colostrum replacer product. Calves fed the colostrum replacer also had a significantly higher percentage of calves with failure of passive transfer (serum IgG <1,000 mg/dL). The colostrum replacer product evaluated in this study failed to routinely provide adequate IgG concentrations when fed according to label directions.

Seeing 2020: America’s New Vision for Integrated Air and Missile Defense

Science.gov (United States)

2015-01-01

MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION /AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13. SUPPLEMENTARY NOTES 14...siles. Examples included the Nike Zeus and Nike -X anti-ballistic missiles (ABMs), which used nuclear warheads to destroy incoming missiles (a practice...the Soviets also explored) in their terminal phase of flight. Yet despite some successful tests, the Nike programs were never fully implemented

A Bayesian perspective on some replacement strategies

International Nuclear Information System (INIS)

Mazzuchi, Thomas A.; Soyer, Refik

1996-01-01

In this paper we present a Bayesian decision theoretic approach for determining optimal replacement strategies. This approach enables us to formally incorporate, express, and update our uncertainty when determining optimal replacement strategies. We develop relevant expressions for both the block replacement protocol with minimal repair and the age replacement protocol and illustrate the use of our approach with real data

75 FR 2549 - Health Center Program

Science.gov (United States)

2010-01-15

... Program AGENCY: Health Resources and Services Administration, HHS ACTION: Notice of Noncompetitive Replacement Award to Regional Health Care Affiliates. SUMMARY: The Health Resources and Services Administration (HRSA) will be transferring Health Center Program (section 330 of the Public Health Service Act...

Central Gulf of Alaska Rockfish Permit Program

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The North Pacific Fishery Management Council adopted the Central Gulf of Alaska Rockfish Program (Rockfish Program) on June 14, 2010, to replace the expiring Pilot...

Can we replace curation with information extraction software?

Science.gov (United States)

Karp, Peter D

2016-01-01

Can we use programs for automated or semi-automated information extraction from scientific texts as practical alternatives to professional curation? I show that error rates of current information extraction programs are too high to replace professional curation today. Furthermore, current IEP programs extract single narrow slivers of information, such as individual protein interactions; they cannot extract the large breadth of information extracted by professional curators for databases such as EcoCyc. They also cannot arbitrate among conflicting statements in the literature as curators can. Therefore, funding agencies should not hobble the curation efforts of existing databases on the assumption that a problem that has stymied Artificial Intelligence researchers for more than 60 years will be solved tomorrow. Semi-automated extraction techniques appear to have significantly more potential based on a review of recent tools that enhance curator productivity. But a full cost-benefit analysis for these tools is lacking. Without such analysis it is possible to expend significant effort developing information-extraction tools that automate small parts of the overall curation workflow without achieving a significant decrease in curation costs.Database URL. © The Author(s) 2016. Published by Oxford University Press.

Waiting for total knee replacement surgery: factors associated with pain, stiffness, function and quality of life

Directory of Open Access Journals (Sweden)

Dionne Clermont E

2009-05-01

Full Text Available Abstract Background Recent evidences show that education and rehabilitation while waiting for knee replacement have positive effects on the patients' health status. Identification of factors associated with worse pain, function and health-related quality of life (HRQoL while waiting for surgery could help develop pre-surgery rehabilitation interventions that target specifically these factors and prioritize patients that may benefit the most from them. The objectives of this study were to measure pain, stiffness, function and HRQoL in patients at enrolment on waiting lists for knee replacement and to identify demographic, clinical, socioeconomic and psychosocial characteristics associated with these outcomes. Methods This study is part of a broader study measuring the effects of pre-surgery wait in patients scheduled for knee replacement. From 02/2006 to 09/2007, 197 patients newly scheduled for total knee replacement were recruited from the waiting lists of three university hospitals in Quebec City, Canada. Pain, stiffness and function were measured with the Western Ontario and McMaster Osteoarthritis Index (WOMAC and HRQoL was measured with the SF-36 Health Survey. Stepwise multiple regression analysis was used to assess the strength of the associations between the independent variables and the WOMAC and SF-36 scores. Results The scores of all eight HRQoL physical and mental domains of the SF-36 were significantly lower than aged matched Canadian normative data (p Conclusion Patients waiting for knee replacement have poor function and HRQoL. Characteristics that were found to be associated with these outcomes could help develop pre-surgery rehabilitation program and prioritize patients that may benefit the most from them. Such programs could include interventions to reduce psychological distress, therapeutic exercises targeting both knees and weight loss management.

Replacement of sub-systems

International Nuclear Information System (INIS)

Rosen, S.E.

1992-01-01

This paper describes a number of quality aspects related to replacement of important systems or components in a nuclear power station. Reference is given to the steam generator replacement and power uprating performed at Ringhals 2 in Sweden in 1989. Since quality is a wide concept there has been put special emphasis in this paper to the important aspects that traditionally are not connected to quality. (author) 1 fig

Prerequisites for a nuclear weapons convention

International Nuclear Information System (INIS)

Liebert, W.

1999-01-01

A Nuclear Weapons Convention (NWC) would prohibit the research, development, production, testing, stockpiling, transfer, use and threat of use of nuclear weapons and would serve their total elimination.' In this fashion it follows the model laid out by the biological and chemical weapons conventions. The NWC would encompass a few other treaties and while replacing them should learn from their experiences. The Nuclear Weapons Convention should at some given point in the future replace the Non-Proliferation Treaty (NPT) and so resolve its contradictions and shortcomings. The main objectives of an NWC Would be: reduction of the nuclear arsenals of the 'five' nuclear weapons powers down to zero within a set of fixed periods of time; elimination of stockpiles of weapons-usable materials and, where existent, nuclear warheads in de-facto nuclear weapon and threshold states; providing assurance that all states will retain their non-nuclear status forever

A complex method of equipment replacement planning. An advanced plan for the replacement of medical equipment.

Science.gov (United States)

Dondelinger, Robert M

2004-01-01

This complex method of equipment replacement planning is a methodology; it is a means to an end, a process that focuses on equipment most in need of replacement, rather than the end itself. It uses data available from the maintenance management database, and attempts to quantify those subjective items important [figure: see text] in making equipment replacement decisions. Like the simple method of the last issue, it is a starting point--albeit an advanced starting point--which the user can modify to fit their particular organization, but the complex method leaves room for expansion. It is based on sound logic, documented facts, and is fully defensible during the decision-making process and will serve your organization well as provide a structure for your equipment replacement planning decisions.

B Plant process piping replacement feasibility study

International Nuclear Information System (INIS)

Howden, G.F.

1996-01-01

Reports on the feasibility of replacing existing embedded process piping with new more corrosion resistant piping between cells and between cells and a hot pipe trench of a Hanford Site style canyon facility. Provides concepts for replacement piping installation, and use of robotics to replace the use of the canyon crane as the primary means of performing/supporting facility modifications (eg, cell lining, pipe replacement, equipment reinstallation) and operational maintenenace

The replacement research reactor

International Nuclear Information System (INIS)

Cameron, R.

1999-01-01

As a consequences of the government decision in September 1997. ANSTO established a replacement research reactor project to manage the procurement of the replacement reactor through the necessary approval, tendering and contract management stages This paper provides an update of the status of the project including the completion of the Environmental Impact Statement. Prequalification and Public Works Committee processes. The aims of the project, management organisation, reactor type and expected capabilities are also described

Optimal composition of fluid-replacement beverages.

Science.gov (United States)

Baker, Lindsay B; Jeukendrup, Asker E

2014-04-01

The objective of this article is to provide a review of the fundamental aspects of body fluid balance and the physiological consequences of water imbalances, as well as discuss considerations for the optimal composition of a fluid replacement beverage across a broad range of applications. Early pioneering research involving fluid replacement in persons suffering from diarrheal disease and in military, occupational, and athlete populations incurring exercise- and/or heat-induced sweat losses has provided much of the insight regarding basic principles on beverage palatability, voluntary fluid intake, fluid absorption, and fluid retention. We review this work and also discuss more recent advances in the understanding of fluid replacement as it applies to various populations (military, athletes, occupational, men, women, children, and older adults) and situations (pathophysiological factors, spaceflight, bed rest, long plane flights, heat stress, altitude/cold exposure, and recreational exercise). We discuss how beverage carbohydrate and electrolytes impact fluid replacement. We also discuss nutrients and compounds that are often included in fluid-replacement beverages to augment physiological functions unrelated to hydration, such as the provision of energy. The optimal composition of a fluid-replacement beverage depends upon the source of the fluid loss, whether from sweat, urine, respiration, or diarrhea/vomiting. It is also apparent that the optimal fluid-replacement beverage is one that is customized according to specific physiological needs, environmental conditions, desired benefits, and individual characteristics and taste preferences.

Computer simulation of replacement sequences in copper

International Nuclear Information System (INIS)

Schiffgens, J.O.; Schwartz, D.W.; Ariyasu, R.G.; Cascadden, S.E.

1978-01-01

Results of computer simulations of , , and replacement sequences in copper are presented, including displacement thresholds, focusing energies, energy losses per replacement, and replacement sequence lengths. These parameters are tabulated for six interatomic potentials and shown to vary in a systematic way with potential stiffness and range. Comparisons of results from calculations made with ADDES, a quasi-dynamical code, and COMENT, a dynamical code, show excellent agreement, demonstrating that the former can be calibrated and used satisfactorily in the analysis of low energy displacement cascades. Upper limits on , , and replacement sequences were found to be approximately 10, approximately 30, and approximately 14 replacements, respectively. (author)

Permanent Quadriplegia Following Replacement of Voice Prosthesis.

Science.gov (United States)

Ozturk, Kayhan; Erdur, Omer; Kibar, Ertugrul

2016-11-01

The authors presented a patient with quadriplegia caused by cervical spine abscess following voice prosthesis replacement. The authors present the first reported permanent quadriplegia patient caused by voice prosthesis replacement. The authors wanted to emphasize that life-threatening complications may be faced during the replacement of voice prosthesis. Care should be taken during the replacement of voice prosthesis and if some problems have been faced during the procedure patients must be followed closely.

Structural considerations in steam generator replacement

International Nuclear Information System (INIS)

Bertheau, S.R.; Gazda, P.A.

1991-01-01

Corrosion of the tubes and tube-support structures inside pressurized water reactor (PWR) steam generators has led many utilities to consider a replacement of the generators. Such a project is a major undertaking for a utility and must be well planned to ensure an efficient and cost-effective effort. This paper discusses various structural aspects of replacement options, such as total or partial generator replacement, along with their associated pipe cuts; major structural aspects associated with removal paths through the equipment hatch or through an opening in the containment wall, along with the related removal processes; onsite movement and storage of the generators; and the advantages and disadvantages of the removal alternatives. This paper addresses the major structural considerations associated with a steam generator replacement project. Other important considerations (e.g., licensing, radiological concerns, electrical requirements, facilities for management and onsite administrative activities, storage and fabrication activities, and offsite transportation) are not discussed in this paper, but should be carefully considered when undertaking a replacement project

Monthly Program Cost Report (MPCR)

Data.gov (United States)

Department of Veterans Affairs — The Monthly Program Cost Report (MPCR) replaces the Cost Distribution Report (CDR). The MPCR provides summary information about Veterans Affairs operational costs,...

The optimal hormonal replacement modality selection for multiple organ procurement from brain-dead organ donors

Directory of Open Access Journals (Sweden)

Mi Z

2014-12-01

Full Text Available Zhibao Mi,1 Dimitri Novitzky,2 Joseph F Collins,1 David KC Cooper3 1Cooperative Studies Program Coordinating Center, VA Maryland Health Care Systems, Perry Point, MD, USA; 2Department of Cardiothoracic Surgery, University of South Florida, Tampa, FL, USA; 3Thomas E Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, USA Abstract: The management of brain-dead organ donors is complex. The use of inotropic agents and replacement of depleted hormones (hormonal replacement therapy is crucial for successful multiple organ procurement, yet the optimal hormonal replacement has not been identified, and the statistical adjustment to determine the best selection is not trivial. Traditional pair-wise comparisons between every pair of treatments, and multiple comparisons to all (MCA, are statistically conservative. Hsu’s multiple comparisons with the best (MCB – adapted from the Dunnett’s multiple comparisons with control (MCC – has been used for selecting the best treatment based on continuous variables. We selected the best hormonal replacement modality for successful multiple organ procurement using a two-step approach. First, we estimated the predicted margins by constructing generalized linear models (GLM or generalized linear mixed models (GLMM, and then we applied the multiple comparison methods to identify the best hormonal replacement modality given that the testing of hormonal replacement modalities is independent. Based on 10-year data from the United Network for Organ Sharing (UNOS, among 16 hormonal replacement modalities, and using the 95% simultaneous confidence intervals, we found that the combination of thyroid hormone, a corticosteroid, antidiuretic hormone, and insulin was the best modality for multiple organ procurement for transplantation. Keywords: best treatment selection, brain-dead organ donors, hormonal replacement, multiple binary endpoints, organ procurement, multiple comparisons

Development of Mortar Simulator with Shell-In-Shell System – Problem of External Ballistics

Directory of Open Access Journals (Sweden)

A. Fedaravicius

2007-01-01

Full Text Available The shell-in-shell system used in the mortar simulator raises a number of non-standard technical and computational problems starting from the requirement to distribute the propelling blast energy between the warhead and the ballistic barrel, finishing with the requirement that the length of warhead's flight path must be scaled to combat shell firing tables. The design problem of the simulator is split into two parts – the problem of external ballistics where the initial velocities of the warhead must be determined, and the problem of internal ballistics – where the design of the cartridge and the ballistic barrel must be performed.

76 FR 27649 - HIV/AIDS Bureau Policy Notice 11-01 (Replaces Policy Notice 99-02)

Science.gov (United States)

2011-05-12

... Bureau Policy Notice 11-01 (Replaces Policy Notice 99- 02) AGENCY: Health Resources and Services.../AIDS Bureau (HAB) Policy Notice 99-02 established policies for the use of Ryan White HIV/AIDS Program... and short-term or emergency housing needs. Amendment 1 to Policy Notice 99-02, effective March 27...

Knee Replacement

Science.gov (United States)

... days. Medications prescribed by your doctor should help control pain. During the hospital stay, you'll be encouraged to move your ... exercise your new knee. After you leave the hospital, you'll continue physical ... mobility and a better quality of life. And most knee replacements can be ...

7 CFR 550.39 - Equipment replacement insurance.

Science.gov (United States)

2010-01-01

... 7 Agriculture 6 2010-01-01 2010-01-01 false Equipment replacement insurance. 550.39 Section 550.39... Agreements Equipment/property Standards § 550.39 Equipment replacement insurance. If required by the terms and conditions of the award, the Cooperator shall provide adequate insurance coverage for replacement...

30 CFR 75.1438 - End attachment replacement.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false End attachment replacement. 75.1438 Section 75.1438 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND... attachment replacement. Wire rope attachments shall be replaced when cracked, deformed, or excessively worn. ...

Missileer: The Dawn, Decline, and Reinvigoration of America’s Intercontinental Ballistic Missile Operators

Science.gov (United States)

2017-06-01

senior captains and field grade officers to operate and manage space systems. Over a two-decade period, it became the norm for approximately 80...will continue to present the same personnel challenges that have existed since the early 1960s. The operational norms established by Minuteman... capped B-2 numbers, cancelled small-ICBM program, ended W- 88 warhead production 24 Mar - Open Skies Treaty Allows for reciprocal unarmed aerial

Life management for a non replaceable structure: the reactor building

International Nuclear Information System (INIS)

Torres, V.; Francia, L.

1998-01-01

Phase 1 of UNESA N.P.P. Lifetime Management Project identified and ranked important components, relative to plant life management. The list showed the Reactor Containment Structure in the third position, and thirteen concrete structures were among the list top twenty. Since the Reactor Containment Building, together with the Reactor Vessel, is the only non-replaceable plant component, and has a big impact on the plant technical life, there is an increasing interest on understanding its behavior to maintain structural integrity. This paper presents: a) IAEA (International Atomic Energy Agency) Coordinated Research Program experiences and studies. Under this Program, international experts address the most frequent degradation mechanisms affecting the containment building. b) IAEA Aging Management Program adapted to our plants. The paper addresses the aging mechanisms affecting the concrete structures, reinforcing steel and prestress systems as well as the aging management programs and the mitigation and control methods. Finally, this paper presents a new module called STRUCTURES, included in phase 2 of the above mentioned project, which will monitor and document the different aging mechanisms and management programs described in item b) regarding the Reactor Containment Building (concrete liner, post stressing system, anchor elements). This module will also support the Maintenance Rule related practices. (Author)

Nutritional programming of reproductive development in heifers

Science.gov (United States)

Developmental programming is the biological process by which environmental factors influence the development of the organs and tissues in the body. There are two areas of developmental programming being investigated with applicability to beef production systems to improve performance of replacement...

49 CFR 541.6 - Requirements for replacement parts.

Science.gov (United States)

2010-10-01

... 49 Transportation 6 2010-10-01 2010-10-01 false Requirements for replacement parts. 541.6 Section....6 Requirements for replacement parts. (a) Each replacement part for a part specified in § 541.5(a) must have the registered trademark of the manufacturer of the replacement part, or some other unique...

Remote handling demonstration of ITER blanket module replacement

International Nuclear Information System (INIS)

Kakudate, S.; Nakahira, M.; Oka, K.; Taguchi, K.; Obara, K.; Tada, E.; Shibanuma, K.; Tesini, A.; Haange, R.; Maisonnier, D.

2001-01-01

In ITER, the in-vessel components such as blanket are to be maintained or replaced remotely since they will be activated by 14 MeV neutrons, and a complete exchange of shielding blanket with breeding blanket is foreseen after the Basic Performance Phase. The blanket is segmented into about seven hundred modules to facilitate remote maintainability and allow individual module replacement. For this, the remote handing equipment for blanket maintenance is required to handle a module with a dead weight of about 4 tonne within a positioning accuracy of a few mm under intense gamma radiation. According to the ITER R and D program, a rail-mounted vehicle manipulator system was developed and the basic feasibility of this system was verified through prototype testing. Following this, development of full-scale remote handling equipment has been conducted as one of the ITER Seven R and D Projects aiming at a remote handling demonstration of the ITER blanket. As a result, the Blanket Test Platform (BTP) composed of the full-scale remote handling equipment has been completed and the first integrated performance test in March 1998 has shown that the fabricate remote handling equipment satisfies the main requirements of ITER blanket maintenance. (author)

30 CFR 57.19028 - End attachment replacement.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false End attachment replacement. 57.19028 Section 57.19028 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Hoisting Wire Ropes § 57.19028 End attachment replacement. Wire rope attachments shall be replaced when...

30 CFR 56.19028 - End attachment replacement.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false End attachment replacement. 56.19028 Section 56.19028 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Wire Ropes § 56.19028 End attachment replacement. Wire rope attachments shall be replaced when cracked...

30 CFR 77.1438 - End attachment replacement.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false End attachment replacement. 77.1438 Section 77.1438 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND... Personnel Hoisting Wire Ropes § 77.1438 End attachment replacement. Wire rope attachments shall be replaced...

Opportunistic replacement of fusion power system parts

International Nuclear Information System (INIS)

Day, J.A.; George, L.L.

1981-01-01

This paper describes a maintenance problem in a fusion power plant. The problem is to specify which life limited parts should be replaced when there is an opportunity. The objective is to minimize the cost rate of replacement parts and of maintenance actions while satisfying a power plant availability constraint. The maintenance policy is to look ahead and replace all parts that will reach their life limits within a time called a screen. Longer screens yield greater system availabilities because more parts are replaced prior to their life limits

Risks of hip and knee replacement

Science.gov (United States)

... is normal to lose blood during and after hip or knee replacement surgery. Some people need a ... clot form are higher during and soon after hip or knee replacement surgery. Sitting or lying down ...

Skilled nursing facilities after joint replacement

Science.gov (United States)

... care providers in the weeks before your joint replacement. They can advise you about whether going directly ... of many people who have had a joint replacement? Can they tell you how many? A good ...

Status of the beryllium replacement project

Energy Technology Data Exchange (ETDEWEB)

Dimayuga, I. [Atomic Energy of Canada, Chalk River, Ontario (Canada); Corcoran, E. [Royal Military College of Canada, Kingston, Ontario (Canada); Daniels, T. [Ontario Power Generation, Pickering, Ontario (Canada); Harmsen, J. [Cameco Fuel Manufacturing Inc., Port Hope, Ontario (Canada); Lu, E. [Bruce Power, Tiverton, Ontario (Canada); Onderwater, T.; Palleck, S. [General Electric- Hitachi, Wilmington, North Carolina (United States); Pant, A. [Cameco Fuel Manufacturing Inc., Port Hope, Ontario (Canada)

2013-07-01

Currently, beryllium (Be) is used as the filler metal for brazing appendages on the sheaths of CANDU® fuel elements. Because of its toxicity, occupational exposure limits for Be are being reduced to very low levels, resulting in significant challenges to CANDU® fuel fabricators. The CANDU® Owners Group (COG) initiated a test program to identify a filler material to replace Be and confirm that the brazed joints meet the established technical requirements for CANDU® fuel. Together with eliminating health risks associated with the use of Be, the industry needs to be assured that continuation of fuel supply remains unaffected and that fuel fabrication processes continue to comply with health and safety standards. A literature survey of studies on brazing and joining of Zircaloy identified potential filler materials that can meet or exceed existing design requirements of the brazed joint, including the required mechanical, microstructural, corrosion resistance, and irradiation properties equivalent to those obtained with Be as braze material. Candidate materials were evaluated against several criteria, including manufacturability, melting point, wettability, mechanical properties, corrosion resistance, effect on neutron economy, potential activation products, and interaction with fuel channels and other related disciplines. This exercise resulted in a list of promising candidate materials that were recommended for the first phase of testing. These materials include stainless steel (304 or 316), Al-Si, Ni-P, and Zr-Mn alloys. To allow a CANDU® utility have sufficient confidence in considering implementation of a different braze filler material, a Be Replacement Test Program, involving out-reactor and in-reactor tests, is being undertaken as a collaborative endeavour by the Canadian nuclear industry. The out-reactor tests consist of: a constructability assessment to determine the material’s suitability with current fuel manufacturing methods; evaluation of

Relations of hedonic hunger and behavioral change to weight loss among adults in a behavioral weight loss program utilizing meal-replacement products.

Science.gov (United States)

Theim, Kelly R; Brown, Joshua D; Juarascio, Adrienne S; Malcolm, Robert R; O'Neil, Patrick M

2013-11-01

Greater self-regulatory behavior usage is associated with greater weight loss within behavioral weight loss treatments. Hedonic hunger (i.e., susceptibility to environmental food cues) may impede successful behavior change and weight loss. Adult men and women (N = 111, body mass index M ± SD = 35.89 ± 6.97 kg/m(2)) were assessed before and after a 15-week lifestyle change weight loss program with a partial meal-replacement diet. From pre- to post-treatment, reported weight control behavior usage improved and hedonic hunger decreased, and these changes were inversely related. Individuals with higher hedonic hunger scores at baseline showed the greatest weight loss. Similarly, participants with lower baseline use of weight control behaviors lost more weight, and increased weight control behavior usage was associated with greater weight loss-particularly among individuals with low baseline hedonic hunger. Further study is warranted regarding the significance of hedonic hunger in weight loss treatments.

The use of transcatheter aortic valve replacement vs surgical aortic valve replacement for the treatment of aortic stenosis

Directory of Open Access Journals (Sweden)

Jensen HA

2015-08-01

Full Text Available Hanna A Jensen, Lillian L Tsai, Vinod H Thourani Division of Cardiothoracic Surgery, Joseph B Whitehead Department of Surgery, Structural Heart and Valve Center, Emory University School of Medicine, Atlanta, GA, USA Abstract: Severe aortic stenosis (AS is associated with considerable morbidity and mortality and is increasing in prevalence as the global population increases. Since AS primarily affects the elderly, many of these patients have comorbidities that make them poor candidates for the gold standard treatment for AS, surgical aortic valve replacement. Transcatheter aortic valve replacement has emerged as a novel technology for the management of AS in higher risk patients over the past decade. Randomized trials have established the safety and efficacy of transcatheter aortic valve replacement, and the medical community has rallied to identify the patients who are most suitable for this transformative treatment. This review focuses on outlining the key procedural differences, describing the unique challenges of both operations, and finally assessing and comparing outcomes both on a general level and in challenging patient subgroups. Keywords: aortic valve replacement, transcatheter aortic valve replacement, surgical aortic valve replacement 

Long-life slab replacement concrete : [summary].

Science.gov (United States)

2015-04-01

Concrete slab replacement projects in Florida have demonstrated a high incidence of : replacement slab cracking. Causes of cracking have not been reliably determined. University of South Florida researchers : sought to identify the factors or : param...

Characteristics of Australian smokers using bupropion and nicotine-replacement therapies.

Science.gov (United States)

Doran, Christopher; Stafford, Jennifer; Shanahan, Marian; Mattick, Richard P

2007-02-01

Smokers were surveyed using a computer-assisted telephone interview to explore behaviors associated with the use of bupropion and nicotine-replacement therapies, using a convenient sample of Australian smokers. With assistance from the Pharmacy Guild of Australia, smokers were recruited through pharmacies and interviewed at baseline and after 3 months. A total of 508 smokers were recruited, 396 were interviewed at baseline and 318 completed a 3-month computer-assisted telephone interview. At 3 months, over two-thirds of participants were still smoking, the majority daily. However, the number of cigarettes smoked per week reduced and the time taken before smoking the first cigarette after waking increased. Nearly all participants started their medication (94%), while only 39% completed the full course. The main reasons for not completing the full course were adverse side effects, such as abnormal dreams and sleep disturbance. Despite Australian guidelines for bupropion and nicotine-replacement therapies to be used within a comprehensive treatment program, only 11% of patients were recommended behavioral support for nicotine dependence by their doctor or pharmacist. The results of the study shed light on patient utilization of the medication in terms of uptake and completion, possible side effects experienced and use of adjuncts. A better understanding of the use and experience of bupropion and nicotine-replacement therapies, and the lack of behavioral support offered with these, provides policy makers with a stronger evidence base to refine and improve the use of such pharmacotherapies.

Hip or knee replacement - in the hospital after

Science.gov (United States)

Hip replacement surgery - after - self-care; Knee replacement surgery - after - self-care ... taking walks in the hallways with help. After knee replacement, some surgeons recommend using a continuous passive ...

Temelin NPP - IandC replacement

International Nuclear Information System (INIS)

Spalenka, I.

1997-01-01

The original instrumentation and control system of the Temelin nuclear power plant is being upgraded and replaced by a modern Westinghouse-supplied system which meets the requirements imposed on current nuclear power plant designs. The history and purpose of the IandC system replacement is given, and the design of the new system is described in some detail. (A.K.)

Replacement research reactor for Australia

International Nuclear Information System (INIS)

Miller, Ross

1998-01-01

In 1992, the Australian Government commissioned a review into the need for a replacement research reactor. That review concluded that in about years, if certain conditions were met, the Government could make a decision in favour of a replacement reactor. A major milestone was achieved when, on 3 September 1997, the Australian Government announced the construction of a replacement research reactor at the site of Australia's existing research reactor HIFAR, subject to the satisfactory outcome of an environmental assessment process. The reactor will be have the dual purpose of providing a first class facility for neutron beam research as well as providing irradiation facilities for both medical isotope production and commercial irradiations. The project is scheduled for completion before the end of 2005. (author)

Hormone Replacement Therapy and Your Heart

Science.gov (United States)

Hormone replacement therapy and your heart Are you taking — or considering — hormone therapy to treat bothersome menopausal symptoms? Understand ... you. By Mayo Clinic Staff Long-term hormone replacement therapy used to be routinely prescribed for postmenopausal ...

HedgeHOGS: A Rapid Nuclear Hedge Sizing and Analysis Tool

Energy Technology Data Exchange (ETDEWEB)

Reynolds, Adam F. [United States Military Academy, West Point, NY (United States); Steinfeldt, Bradley Alexander [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Lafleur, Jarret Marshall [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Hawley, Marilyn F. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Shannon, Lisa M. [Sandia National Lab. (SNL-CA), Livermore, CA (United States)

2017-07-01

The U.S. nuclear stockpile hedge is an inventory of non-deployed nuclear warheads and a force structure capable of deploying those warheads. Current guidance is to retain this hedge to mitigate the risk associated with the technical failure of any single warhead type or adverse geopolitical developments that could require augmentation of the force. The necessary size of the hedge depends on the composition of the nuclear stockpile and assumed constraints. Knowing the theoretical minimum hedge given certain constraints is useful when considering future weapons policy. HedgeHOGS, an Excel-based tool, was developed to enable rapid calculation of the minimum hedge size associated with varying active stockpile composition and hedging strategies.

Managing military uranium and plutonium in the United States and the former Soviet Union

International Nuclear Information System (INIS)

Bunn, M.; Holdren, J.P.

1997-01-01

Effective approaches to the management of plutonium and highly enriched uranium (HEU)--the essential ingredients of nuclear weapons--are fundamental to controlling nuclear proliferation and providing the basis for deep, transparent, and irreversible reductions in nuclear weapons stockpiles. The collapse of the Soviet Union and the ongoing dismantlement of tens of thousands of nuclear weapons are creating unprecedented stresses on the systems for managing these materials, as well as unprecedented opportunities for cooperation to improve these systems. In this article, the authors summarize the technical background to this situation, and the current and prospective security challenges posed by military stockpiles of these materials in the US and Russia. They then review the programs in place to address these challenges, the progress of these programs to date, and the work remaining to be done, in five areas: (a) preventing theft and smuggling of nuclear warheads and fissile materials; (b) building a regime of monitored reductions in nuclear warhead and fissile material stockpiles; (c) ending further production of excess fissile materials; (d) reducing stockpiles of excess fissile materials; and (e) avoiding economic collapse in the nuclear cities where substantial fractions of these materials and their guardians reside. 128 refs., 1 fig., 3 tabs

New one cycle criteria for optimizing preventive replacement policies

International Nuclear Information System (INIS)

Hamidi, Maryam; Szidarovszky, Ferenc; Szidarovszky, Miklos

2016-01-01

Models are introduced and examined for the optimum scheduling of preventive replacements. The “replace first” and “replace last” models are known from the literature if the long term expected cost per unit time is minimized. We will first introduce the one cycle counterparts of these models when the expected costs per unit time in a single cycle is minimized. If the unit performs identical projects sequentially then the “replace next” model assumes that the preventive replacement is postponed until the ongoing project is finished. The termination time of this project is random which also depends on the scheduled time of the preventive replacement in contrary to the “replace first” and “replace last” models. The mathematical models are formulated and conditions are given for the existence of finite optima. Numerical examples and a simulation study illustrate the methodology and the numerical results show interesting comparisons of the different models. - Highlights: • The Single cycle age replacement model is extended incorporating repairable failures. • In order to avoid project interruption costs, three model variants are discussed. • Model variants are replace first, replace last and replace next. • In many cases analytic solutions are derived and illustrated by numerical examples. • The different model variants and their results are compared based on simulation studies.

Nuclear facilities: repair and replacement technologies

International Nuclear Information System (INIS)

2005-01-01

The oldest operating reactors are more than 35 years old and are now facing major maintenance operations. The first replacement of a pressurizer took place in autumn 2005 at the St-Lucie plant (Usa) while steam generators have been currently replaced since 1983. Nuclear industry has to adapt to this new market by proposing innovative technological solutions in the reactor maintenance field. This document gathers the 9 papers presented at the conference. The main improvements concern repair works on internal components of PWR-type reactors, the replacement of major components of the primary coolant circuit and surface treatments to limit the propagation of damages. The first paper shows that adequate design and feedback experience are good assets to manage the ageing of a nuclear unit. Another paper shows that a new repair method of a relief valve can avoid its replacement. (A.C.)

Replacement Saltwell Pumping System Document Bibliography

International Nuclear Information System (INIS)

BELLOMY, J.R.

2000-01-01

This document bibliography is prepared to identify engineering documentation developed during the design of the Replacement Saltwell Pumping System. The bibliography includes all engineering supporting documents and correspondence prepared prior to the deployment of the system in the field. All documents referenced are available electronically through the Records Management Information System (RMIS). Major components of the Replacement Saltwell Pumping System include the Sundyne Canned Motor Pump, the Water Filter Skid, the Injection Water Skid and the Backflow Preventer Assembly. Drawing H-14-104498 provides an index of drawings (fabrication details, PandIDs, etc.) prepared to support development of the Replacement Saltwell Pumping System. Specific information pertaining to new equipment can be found in Certified Vendor Information (CVI) File 50124. This CVI file has been established specifically for new equipment associated with the Replacement Saltwell Pumping System

The Cost-Effectiveness of Replacing the Bottom Quartile of Novice Teachers through Value-Added Teacher Assessment

Science.gov (United States)

Yeh, Stuart S.; Ritter, Joseph

2009-01-01

A cost-effectiveness analysis was conducted of Gordon, Kane, and Staiger's (2006) proposal to raise student achievement by identifying and replacing the bottom quartile of novice teachers, using value-added assessment of teacher performance. The cost effectiveness of this proposal was compared to the cost effectiveness of voucher programs, charter…

Knee joint replacement

Science.gov (United States)

... to make everyday tasks easier. Practice using a cane, walker , crutches , or a wheelchair correctly. On the ... ask your doctor Knee joint replacement - discharge Preventing falls Preventing falls - what to ask your doctor Surgical ...

Evolution of high tooth replacement rates in sauropod dinosaurs.

Science.gov (United States)

D'Emic, Michael D; Whitlock, John A; Smith, Kathlyn M; Fisher, Daniel C; Wilson, Jeffrey A

2013-01-01

Tooth replacement rate can be calculated in extinct animals by counting incremental lines of deposition in tooth dentin. Calculating this rate in several taxa allows for the study of the evolution of tooth replacement rate. Sauropod dinosaurs, the largest terrestrial animals that ever evolved, exhibited a diversity of tooth sizes and shapes, but little is known about their tooth replacement rates. We present tooth replacement rate, formation time, crown volume, total dentition volume, and enamel thickness for two coexisting but distantly related and morphologically disparate sauropod dinosaurs Camarasaurus and Diplodocus. Individual tooth formation time was determined by counting daily incremental lines in dentin. Tooth replacement rate is calculated as the difference between the number of days recorded in successive replacement teeth. Each tooth family in Camarasaurus has a maximum of three replacement teeth, whereas each Diplodocus tooth family has up to five. Tooth formation times are about 1.7 times longer in Camarasaurus than in Diplodocus (315 vs. 185 days). Average tooth replacement rate in Camarasaurus is about one tooth every 62 days versus about one tooth every 35 days in Diplodocus. Despite slower tooth replacement rates in Camarasaurus, the volumetric rate of Camarasaurus tooth replacement is 10 times faster than in Diplodocus because of its substantially greater tooth volumes. A novel method to estimate replacement rate was developed and applied to several other sauropodomorphs that we were not able to thin section. Differences in tooth replacement rate among sauropodomorphs likely reflect disparate feeding strategies and/or food choices, which would have facilitated the coexistence of these gigantic herbivores in one ecosystem. Early neosauropods are characterized by high tooth replacement rates (despite their large tooth size), and derived titanosaurs and diplodocoids independently evolved the highest known tooth replacement rates among archosaurs.

Evolution of high tooth replacement rates in sauropod dinosaurs.

Directory of Open Access Journals (Sweden)

Michael D D'Emic

Full Text Available BACKGROUND: Tooth replacement rate can be calculated in extinct animals by counting incremental lines of deposition in tooth dentin. Calculating this rate in several taxa allows for the study of the evolution of tooth replacement rate. Sauropod dinosaurs, the largest terrestrial animals that ever evolved, exhibited a diversity of tooth sizes and shapes, but little is known about their tooth replacement rates. METHODOLOGY/PRINCIPAL FINDINGS: We present tooth replacement rate, formation time, crown volume, total dentition volume, and enamel thickness for two coexisting but distantly related and morphologically disparate sauropod dinosaurs Camarasaurus and Diplodocus. Individual tooth formation time was determined by counting daily incremental lines in dentin. Tooth replacement rate is calculated as the difference between the number of days recorded in successive replacement teeth. Each tooth family in Camarasaurus has a maximum of three replacement teeth, whereas each Diplodocus tooth family has up to five. Tooth formation times are about 1.7 times longer in Camarasaurus than in Diplodocus (315 vs. 185 days. Average tooth replacement rate in Camarasaurus is about one tooth every 62 days versus about one tooth every 35 days in Diplodocus. Despite slower tooth replacement rates in Camarasaurus, the volumetric rate of Camarasaurus tooth replacement is 10 times faster than in Diplodocus because of its substantially greater tooth volumes. A novel method to estimate replacement rate was developed and applied to several other sauropodomorphs that we were not able to thin section. CONCLUSIONS/SIGNIFICANCE: Differences in tooth replacement rate among sauropodomorphs likely reflect disparate feeding strategies and/or food choices, which would have facilitated the coexistence of these gigantic herbivores in one ecosystem. Early neosauropods are characterized by high tooth replacement rates (despite their large tooth size, and derived titanosaurs and

Home-Based versus Hospital-Based Rehabilitation Program after Total Knee Replacement

Directory of Open Access Journals (Sweden)

Remedios López-Liria

2015-01-01

Full Text Available Objectives. To compare home-based rehabilitation with the standard hospital rehabilitation in terms of improving knee joint mobility and recovery of muscle strength and function in patients after a total knee replacement. Materials and Methods. A non-randomised controlled trial was conducted. Seventy-eight patients with a prosthetic knee were included in the study and allocated to either a home-based or hospital-based rehabilitation programme. Treatment included various exercises to restore strength and joint mobility and to improve patients’ functional capacity. The primary outcome of the trial was the treatment effectiveness measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC. Results. The groups did not significantly differ in the leg side (right/left or clinical characteristics (P>0.05. After the intervention, both groups showed significant improvements (P<0.001 from the baseline values in the level of pain (visual analogue scale, the range of flexion-extension motion and muscle strength, disability (Barthel and WOMAC indices, balance, and walking. Conclusions. This study reveals that the rehabilitation treatments offered either at home or in hospital settings are equally effective.

New Firm Performance and the Replacement of Founder-CEOs

DEFF Research Database (Denmark)

Chen, Jing; Thompson, Peter

2015-01-01

We study the causes and consequences of the replacement of founder-CEOs in a sample of 4,172 Danish start-ups. We propose that founder-CEO replacement is driven in part by mismatches between business quality and founder ability. Our framework suggests that replacements are more likely among...... the worst- and best-performing firms, with low (high)-ability founders replaced by manager with higher (lower) ability. Replacement is not unambiguously associated with better subsequent performance. Firms that replaced the founder were much more likely to fail, but the surviving firms among them grew...

Age replacement models: A summary with new perspectives and methods

International Nuclear Information System (INIS)

Zhao, Xufeng; Al-Khalifa, Khalifa N.; Magid Hamouda, Abdel; Nakagawa, Toshio

2017-01-01

Age replacement models are fundamental to maintenance theory. This paper summarizes our new perspectives and hods in age replacement models: First, we optimize the expected cost rate for a required availability level and vice versa. Second, an asymptotic model with simple calculation is proposed by using the cumulative hazard function skillfully. Third, we challenge the established theory such that preventive replacement should be non-random and only corrective replacement should be made for the unit with exponential failure. Fourth, three replacement policies with random working cycles are discussed, which are called overtime replacement, replacement first, and replacement last, respectively. Fifth, the policies of replacement first and last are formulated with general models. Sixth, age replacement is modified for the situation when the economical life cycle of the unit is a random variable with probability distribution. Finally, models of a parallel system with constant and random number of units are taken into considerations. The models of expected cost rates are obtained and optimal replacement times to minimize them are discussed analytically and computed numerically. Further studies and potential applications are also indicated at the end of discussions of the above models. - Highlights: • Optimization of cost rate for availability level is discussed and vice versa. • Asymptotic and random replacement models are discussed. • Overtime replacement, replacement first and replacement last are surveyed. • Replacement policy with random life cycle is given. • A parallel system with random number of units is modeled.

Report on the meeting for examining replacing core

International Nuclear Information System (INIS)

1977-01-01

At the time of examining the application for approval of reactor installation, it must be confirmed that the safety of the concerned reactor is secured with not only the initially loaded core but also the replacing core. Besides, it must be confirmed again that the various criteria concerning the safety are satisfied after the start of operation, because a part of the parameters of the replacing core is dependent on the operational history. On the above described viewpoints, the main parameters affecting the safety and the nuclear and thermal limits of replacing core were reviewed. Moreover, the contents of description concerning replacing core in the application form were examined. As the general matters concerning the safety of replacing core, the scram reactivity curves for BWRs and PWRs, the method of description in the application form concerning the fuel containing gadolinia, and the use of burnable poison in replacing core were examined. The meeting for examining replacing core was organized on September 20, 1976, at the Committee for Examining Reactor Safety, and this report was compiled as the results of 10 meetings. (Kako, I.)

Clinical Application of Scaffolds for Partial Meniscus Replacement.

Science.gov (United States)

Moran, Cathal J; Withers, Daniel P; Kurzweil, Peter R; Verdonk, Peter C

2015-09-01

Meniscal tears are common injuries often treated by partial meniscectomy. This may result in altered joint contact mechanics which in turn may lead to worsening symptoms and an increased risk of osteoarthritis. Meniscal scaffolds have been proposed as a treatment option aimed at reducing symptoms while also potentially reducing progression of degenerative change. There are 2 scaffolds available for clinical use at the present time; Collagen Meniscus Implant and Actifit. Medium-term to long-term data (4.9 to 11.3 y) demonstrate efficacy of partial meniscus replacement. The patients who seem to benefit most are chronic postmeniscectomy rather than acute meniscal injuries. Herein we report on available clinical data for Collagen Meniscus Implant and Actifit while describing our preferred surgical technique and postoperative rehabilitation program.

Hip Resurfacing: An Alternative to Conventional Hip Replacement?

Science.gov (United States)

... Is hip resurfacing a good alternative to hip replacement? Answers from Mark Spangehl, M.D. Hip resurfacing has lost favor with many surgeons ... women with poor bone quality. Unlike traditional hip replacement, hip resurfacing doesn't completely replace the "ball" ...

Comparative effectiveness of a portion-controlled meal replacement program for weight loss in adults with and without diabetes/high blood sugar.

Science.gov (United States)

Coleman, C D; Kiel, J R; Mitola, A H; Arterburn, L M

2017-07-10

Individuals with type 2 diabetes (DM2) may be less successful at achieving therapeutic weight loss than their counterparts without diabetes. This study compares weight loss in a cohort of adults with DM2 or high blood sugar (D/HBS) to a cohort of adults without D/HBS. All were overweight/obese and following a reduced or low-calorie commercial weight-loss program incorporating meal replacements (MRs) and one-on-one behavioral support. Demographic, weight, body composition, anthropometric, pulse and blood pressure data were collected as part of systematic retrospective chart review studies. Differences between cohorts by D/HBS status were analyzed using Mann-Whitney U-tests and mixed model regression. A total of 816 charts were included (125 with self-reported D/HBS). The cohort with D/HBS had more males (40.8 vs 25.6%), higher BMI (39.0 vs 36.3 kg m - 2 ) and was older (56 vs 48 years). Among clients continuing on program, the cohorts with and without D/HBS lost, on average, 5.6 vs 5.8 kg (NS) (5.0 vs 5.6%; P=0.005) of baseline weight at 4 weeks, 11.0 vs 11.6 kg (NS) (9.9 vs 11.1%; P=0.027) at 12 weeks and 16.3 vs 17.1 kg (13.9 vs 15.7%; NS) at 24 weeks, respectively. In a mixed model regression controlling for baseline weight, gender and meal plan, and an intention-to-treat analysis, there was no significant difference in weight loss between the cohorts at any time point. Over 70% in both cohorts lost ⩾5% of their baseline weight by the final visit on their originally assigned meal plan. Both cohorts had significant reductions from baseline in body fat, blood pressure, pulse and abdominal circumference. Adults who were overweight/obese and with D/HBS following a commercial weight-loss program incorporating MRs and one-on-one behavioral support achieved therapeutic weight loss. The program was equally effective for weight loss and reductions in cardiometabolic risk factors among adults with and without D/HBS.

Electrocatalysts Prepared by Galvanic Replacement

Directory of Open Access Journals (Sweden)

Athanasios Papaderakis

2017-03-01

Full Text Available Galvanic replacement is the spontaneous replacement of surface layers of a metal, M, by a more noble metal, Mnoble, when the former is treated with a solution containing the latter in ionic form, according to the general replacement reaction: nM + mMnoblen+ → nMm+ + mMnoble. The reaction is driven by the difference in the equilibrium potential of the two metal/metal ion redox couples and, to avoid parasitic cathodic processes such as oxygen reduction and (in some cases hydrogen evolution too, both oxygen levels and the pH must be optimized. The resulting bimetallic material can in principle have a Mnoble-rich shell and M-rich core (denoted as Mnoble(M leading to a possible decrease in noble metal loading and the modification of its properties by the underlying metal M. This paper reviews a number of bimetallic or ternary electrocatalytic materials prepared by galvanic replacement for fuel cell, electrolysis and electrosynthesis reactions. These include oxygen reduction, methanol, formic acid and ethanol oxidation, hydrogen evolution and oxidation, oxygen evolution, borohydride oxidation, and halide reduction. Methods for depositing the precursor metal M on the support material (electrodeposition, electroless deposition, photodeposition as well as the various options for the support are also reviewed.

Steam-generator replacement sets new marks

International Nuclear Information System (INIS)

Beck, R.L.

1995-01-01

This article describes how, in one of the most successful steam-generator replacement experiences at PWRs worldwide, the V C Summer retrofit exceeded plant goals for critical-path duration, radiation, exposure, and radwaste generation. Intensive planning and teamwork, combined with the firm support of station management and the use of mockups to prepare the work crews for activity in a radiological environment, were key factors in the record performance achieved by South Carolina Electric and Gas Co (SCE and G) in replacing three steam generators at V C Summer nuclear station. The 97-day, two-hour breaker-to-breaker replacement outage -- including an eight-day delay for repair of leak in a small-bore seal-injection line of a reactor coolant pump (unrelated to the replacement activities) -- surpassed the project goal by over one day. Moreover, the outage was only 13 hours shy of the world record held by Virginia Power Co's North Anna Unit 1

Replacement of the Advanced Test Reactor control room

International Nuclear Information System (INIS)

Durney, J.L.; Klingler, W.B.

1989-01-01

The control room for the Advanced Test Reactor has been replaced to provide modern equipment utilizing current standards and meeting the current human factors requirements. The control room was designed in the early 1960 era and had not been significantly upgraded since the initial installation. The replacement did not change any of the safety circuits or equipment but did result in replacement of some of the recorders that display information from the safety systems. The replacement was completed in concert with the replacement of the control room simulator which provided important feedback on the design. The design successfully incorporates computer-based systems into the display of the plant variables. This improved design provides the operator with more information in a more usable form than was provided by the original design. The replacement was successfully completed within the scheduled time thereby minimizing the down time for the reactor. 1 fig., 1 tab

Replacement of the Advanced Test Reactor control room

International Nuclear Information System (INIS)

Durney, J.L.; Klingler, W.B.

1990-01-01

The control room for the Advanced Test Reactor has been replaced to provide modern equipment utilizing current standards and meeting the current human factors requirements. The control room was designed in the early 1960 era and had not been significantly upgraded since the initial installation. The replacement did not change any of the safety circuits or equipment but did result in replacement of some of the recorders that display information from the safety systems. The replacement was completed in concert with the replacement of the control room simulator which provided important feedback on the design. The design successfully incorporates computer-based systems into the display of the plant variables. This improved design provides the operator with more information in a more usable form than was provided by the original design. The replacement was successfully completed within the scheduled time thereby minimizing the down time for the reactor

Guide to optimized replacement of equipment seals

International Nuclear Information System (INIS)

Gleason, J.F.

1990-03-01

A reevaluation of current scheduled replacement intervals of polymeric seals in plant equipment can achieve significant benefits. Information is provided which has the potential for increasing replacement intervals based on better information on how seals have performed through unique nuclear industry tests to qualify equipment, improved elastomers and increased knowledge of the failure mechanisms and related performance. The research was performed by reviewing applications of elastomeric seals in nuclear plants and practice associated with defining seal replacement intervals in the nuclear power and other industries. Performance indicators and how they predict degradation of seals were evaluated. Guidelines and a flow chart for reevaluating seal replacement intervals are provided. 29 refs., 38 figs., 8 tabs

NPS TINYSCOPE program management

OpenAIRE

Turner, Christopher Gordon.

2010-01-01

Approved for public release; distribution is unlimited This master's thesis introduces the program management and concept of operations of the TINYSCOPE Program. TINYSCOPE is a 6U CubeSat designed as a low-cost and easily replaceable imaging spacecraft that can produce tactically relevant imagery data. Tactical requirements in this context would emphasize "good enough" image resolution with a rapid-response tasking loop and high revisit rate. The TINYSCOPE project intends to demonstra...

30 CFR 57.19122 - Replacement parts.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Replacement parts. 57.19122 Section 57.19122 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Inspection and Maintenance § 57.19122 Replacement parts. Parts used to repair hoists shall have properties...

30 CFR 56.19122 - Replacement parts.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Replacement parts. 56.19122 Section 56.19122 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Inspection and Maintenance § 56.19122 Replacement parts. Parts used to repair hoists shall have properties...

Partial knee replacement

Science.gov (United States)

... good range of motion in your knee. The ligaments in your knee are stable. However, most people with knee arthritis have a surgery called a total knee arthroplasty (TKA). Knee replacement is most often done in people age 60 ...

ReplacementMatrix: a web server for maximum-likelihood estimation of amino acid replacement rate matrices.

Science.gov (United States)

Dang, Cuong Cao; Lefort, Vincent; Le, Vinh Sy; Le, Quang Si; Gascuel, Olivier

2011-10-01

Amino acid replacement rate matrices are an essential basis of protein studies (e.g. in phylogenetics and alignment). A number of general purpose matrices have been proposed (e.g. JTT, WAG, LG) since the seminal work of Margaret Dayhoff and co-workers. However, it has been shown that matrices specific to certain protein groups (e.g. mitochondrial) or life domains (e.g. viruses) differ significantly from general average matrices, and thus perform better when applied to the data to which they are dedicated. This Web server implements the maximum-likelihood estimation procedure that was used to estimate LG, and provides a number of tools and facilities. Users upload a set of multiple protein alignments from their domain of interest and receive the resulting matrix by email, along with statistics and comparisons with other matrices. A non-parametric bootstrap is performed optionally to assess the variability of replacement rate estimates. Maximum-likelihood trees, inferred using the estimated rate matrix, are also computed optionally for each input alignment. Finely tuned procedures and up-to-date ML software (PhyML 3.0, XRATE) are combined to perform all these heavy calculations on our clusters. http://www.atgc-montpellier.fr/ReplacementMatrix/ olivier.gascuel@lirmm.fr Supplementary data are available at http://www.atgc-montpellier.fr/ReplacementMatrix/

Impact of biological and economic variables on optimal parity for replacement in swine breed-to-wean herds.

Science.gov (United States)

Rodriguez-Zas, S L; Davis, C B; Ellinger, P N; Schnitkey, G D; Romine, N M; Connor, J F; Knox, R V; Southey, B R

2006-09-01

Voluntary and involuntary culling practices determine the average parity when sows are replaced in a herd. Underlying these practices is the economic effect of replacing a sow at different parities. A dynamic programming model was used to find the optimal parity and net present value in breed-to-wean swine herds. The model included income and costs per parity weighted by the discount rate and sow removal rate. Three scenarios that reflect a wide range of cases were considered: low removal rates per parity with no salvage value (LRNS), high removal rates per parity with no salvage value (HRNS), and high removal rates per parity with a percentage of the sows having a salvage value (HRYS). The optimal parity of replacement for the base biological and economic conditions was 4 and 5 parities in the high and low removal scenarios, respectively. Sensitivity analyses identified the variables influencing the optimal replacement parity. Optimal parity of replacement ranged from 3 to 7 parities in the low replacement scenario, compared with 1 to 5 parities in the high replacement scenarios. Sow replacement cost and salvage value had the greatest impact on optimal parity of replacement followed by revenues per piglet weaned. The discount rate and number of parities per year generally had little influence on optimal parity. For situations with high sow costs, low salvage values, and low revenues per piglet, the optimal parity at removal was as high as 6 to 10 parities, and for situations with low sow cost, high salvage values, and high revenues per piglet, the optimal parity at removal was as low as 1 to 2 parities depending on removal rates. The modified internal rate of return suggested that, for most LRNS and HRYS scenarios considered, investment in a swine breed-to-wean enterprise was favored over other investments involving a similar risk profile. Our results indicate that in US breeding herds, sows are culled on average near the optimal parity of 4. However, the

Valve-sparing and valve-replacing techniques for aortic root replacement in patients with Marfan syndrome: Analysis of early outcome.

Science.gov (United States)

Volguina, Irina V; Miller, D Craig; LeMaire, Scott A; Palmero, Laura C; Wang, Xing Li; Connolly, Heidi M; Sundt, Thoralf M; Bavaria, Joseph E; Dietz, Harry C; Milewicz, Dianna M; Coselli, Joseph S

2009-05-01

A prospective, international registry study was initiated to provide contemporary comparative data on short-term clinical outcomes after aortic valve-sparing and aortic valve-replacing root operations in patients with Marfan syndrome. The purpose of this initial report is to describe the study design and to compare early outcomes in the first 151 enrolled patients. We assessed 30-day outcomes in 151 patients who met strict Ghent diagnostic criteria for Marfan syndrome and underwent aortic root replacement with either valve-replacing (n = 46) or valve-sparing techniques (n = 105) at one of 18 participating centers. In the valve replacement group, a mechanical composite valve graft was used in 39 (85%) patients and a bioprosthetic valve in 7 (15%). In the valve-sparing group, David V procedures were performed in 57 (54%) patients, David I in 38 (36%), David IV in 8 (8%), Florida sleeve in 1 (1%), and Yacoub remodeling in 1 (1%). No in-hospital or 30-day deaths occurred. Despite longer crossclamp and cardiopulmonary bypass times in the valve-sparing group, there were no significant between-group differences in postoperative complications. Thirty-day valve-related complications occurred in 2 (4%) patients undergoing valve replacement and in 3 (3%) undergoing valve-sparing procedures (P = .6). The analysis of early outcomes revealed that valve-sparing techniques were the most common approach to root replacement in patients with Marfan syndrome in these centers. The complexity of valve-sparing root replacement did not translate into any demonstrable adverse early outcomes. Subsequent analysis will compare the 3-year durability of these two surgical approaches.

A Bayesian perspective on age replacement with minimal repair

International Nuclear Information System (INIS)

Sheu, S.-H.; Yeh, R.H.; Lin, Y.-B.; Juang, M.-G.

1999-01-01

In this article, a Bayesian approach is developed for determining an optimal age replacement policy with minimal repair. By incorporating minimal repair, planned replacement, and unplanned replacement, the mathematical formulas of the expected cost per unit time are obtained for two cases - the infinite-horizon case and the one-replacement-cycle case. For each case, we show that there exists a unique and finite optimal age for replacement under some reasonable conditions. When the failure density is Weibull with uncertain parameters, a Bayesian approach is established to formally express and update the uncertain parameters for determining an optimal age replacement policy. Further, various special cases are discussed in detail. Finally, a numerical example is given

Steam generator replacement in Bruce A Unit 1 and Unit 2

International Nuclear Information System (INIS)

Hart, R.S.

2006-01-01

and Unit 2 SGR employs a Medium Lift Crane (MLC) located at ground elevation north of the powerhouse to perform all heavy lifts within the reactor buildings, including relocation of the steam drums and removal and replacement of the Steam Generators, through openings created in the reactor building roof structures. Following the removal of components and systems that interfere with SG replacement activities, the connections between the Steam Generators and the steam drums are severed, the roof of the concrete SD enclosure and the steam drum cooling system are removed, and the steam drums are lifted from the steam drum enclosures and placed on temporary supports to the reactor side of the steam drum enclosures by the MLC. The old Steam Generators are then removed and the replacement Steam Generators are installed through the reactor building roof openings by the MLC. The steam drums and all piping connections and equipment will be reinstalled following the installation of the Replacement Steam Generators to establish the 'as found' condition. The replacement of the eight Steam Generators in each unit is a major part of the Unit 1 and Unit 2 rehabilitation program. This work is currently in progress. The Unit 1 and Unit 2 Steam Generator replacement is a 'first-of-a-kind' project. These are the first CANDU Steam Generators to be replaced, and the horizontal steam drum configuration is unique to Bruce A. This paper provides an overview of the Unit 1 and Unit 2 Steam Generator replacement methodology developed and being employed by SLN. (author)

Meal replacements as a strategy for weight loss in obese hemodialysis patients.

Science.gov (United States)

Lassemillante, Annie-Claude M; Oliver, Veronica; Hickman, Ingrid; Murray, Eryn; Campbell, Katrina L

2016-10-01

Introduction There is currently limited evidence on the use or safety of meal replacements as part of a low- or very-low-calorie diet in patients with renal insufficiency; however, these are occasionally used under dietetic supervision in clinical practice to achieve the desired weight loss for kidney transplant. This case series reports on the safety and efficacy of a weight loss practice utilizing meal replacements among hemodialysis patients, who needed to lose weight for kidney transplant. Methods Five hemodialysis patients were prescribed a modified low-calorie diet (950 kcal and 100 g protein per day) comprising three meal replacements (Optifast ® ), one main meal, and two low-potassium fruits per day. Dietary requirements and restrictions were met for all participants. Dialysis prescriptions, weight (predialysis and postdialysis), interdialytic weight gain, biochemistry, and medications were monitored during the study period for up to 12 months. Findings Participants were aged between 46 and 61 years, and the median time on the low-calorie diet was 364 days. Phosphate binders were temporarily ceased for one participant for reasons unrelated to this program and no other safety concerns were recorded. The low-calorie diet resulted in energy deficits ranging from 1170 kcal to 2160 kcal, and all participants lost weight (median 7% [range 5.2%-11.4%]). The most dramatic weight change appeared to occur by week 12, and declining adherence led to erratic weight change thereafter. Discussion This modified low-calorie diet was safe and effective to use in this population. Meal replacements are a useful weight loss strategy in hemodialysis patients, therefore, offering an alternative to usual weight loss protocols. © 2016 International Society for Hemodialysis.

14 CFR 21.9 - Replacement and modification articles.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Replacement and modification articles. 21.9... CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS General § 21.9 Replacement and modification articles. (a) If a person knows, or should know, that a replacement or modification article is reasonably likely to be...

30 CFR 56.12036 - Fuse removal or replacement.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Fuse removal or replacement. 56.12036 Section 56.12036 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND... § 56.12036 Fuse removal or replacement. Fuses shall not be removed or replaced by hand in an energized...

Efforts for optimization of BWR core internals replacement

International Nuclear Information System (INIS)

Iizuka, N.

2000-01-01

The core internal components replacement of a BWR was successfully completed at Fukushima-Daiichi Unit 3 (1F3) of the Tokyo Electric Power Company (TEPCO) in 1998. The core shroud and the majority of the internal components made by type 304 stainless steel (SS) were replaced with the ones made of low carbon type 316L SS to improve Intergranular Stress Corrosion Cracking (IGSCC) resistance. Although this core internals replacement project was completed, several factors combined to result in a longer-than-expected period for the outage. It was partly because the removal work of the internal components was delayed. Learning a lesson from whole experience in this project, some methods were adopted for the next replacement project at Fukushima-Daiichi Unit 2 (1F2) to shorten the outage and reduce the total radiation exposure. Those are new removal processes and new welding machine and so on. The core internals replacement work was ended at 1F2 in 1999, and both the period of outage and the total radiation exposure were the same degree as expected previous to starting of this project. This result shows that the methods adopted in this project are basically applicable for the core internals replacement work and the whole works about the BWR core internals replacement were optimized. The outline of the core internals replacement project and applied technologies at 1F3 and 1F2 are discussed in this paper. (author)

Essential Specification Elements for Heat Exchanger Replacement

Energy Technology Data Exchange (ETDEWEB)

Bower, L.

2015-07-01

Performance upgrade and equipment degradation are the primary impetuses for a nuclear power plant to engage in the large capital cost project of heat exchanger replacement. Along with attention to these issues, consideration of heat exchanger Codes and Standards, material improvements, thermal redesign, and configuration are essential for developing User’s Design Specifications for successful replacement projects. The User’s Design Specification is the central document in procuring ASME heat exchangers. Properly stated objectives for the heat exchanger replacement are essential for obtaining the materials, configurations and thermal designs best suited for the nuclear power plant. Additionally, the code of construction required and the applied manufacturing standard (TEMA or HEI) affects how the heat exchanger may be designed or configured to meet the replacement goals. Knowledge of how Codes and Standards affect design and configuration details will aid in writing the User’s Design Specification. Joseph Oat Corporation has designed and fabricated many replacement heat exchangers for the nuclear power industry. These heat exchangers have been constructed per ASME Section III to various Code-Years or ASME Section VIII-1 to the current Code-Year also in accordance with TEMA and HEI. These heat exchangers have been a range of like-for-like replacement to complete thermal, material and configuration redesigns. Several examples of these heat exchangers with their Code, Standard and specification implications are presented. (Author.

A replaceable reflective film for solar concentrators

Energy Technology Data Exchange (ETDEWEB)

1991-09-01

The 3M Company manufactures a silvered acrylic film called ECP-305 that is regarded as the preferred reflective film for use on stretched-membrane heliostats. However, ECP-305 will degrade in time, due to both corrosion of the silver layer and delamination at the film's silver-to-acrylic interface, and will eventually need to be replaced. 3M uses a very aggressive adhesive on this film, and once it is laminated, replacement is very difficult. The purpose of this investigation was the development of a replaceable reflector, a reflective film that can be easily removed and replaced. A replaceable reflector was successfully configured by laminating ECP-305 to the top surface of a smooth, dimensionally stable polymer film, with a removable adhesive applied to the underside of the polymer film. Several stages of screening and testing led to the selection of a 0.010-inch thick polycarbonate (GE 8030) as the best polymer film and a medium tack tape (3M Y-9425) was selected as the best removable adhesive. To demonstrate the feasibility of the replaceable reflector concept and to provide a real-time field test, the chosen construction was successfully applied to the 50-m{sup 2} SKI heliostat at the Central Receiver Test Facility at Sandia National Laboratories in Albuquerque. 4 refs., 13 figs., 7 tabs.

Replacement Models Revisited | Alabi | Journal of Research in ...

African Journals Online (AJOL)

The objective is to review the annual total cost and the cumulative annual total cost average hitherto used as replacement methods. The study showed some disparity in the optimal age of single replacement as used by some authors. Hence, an arithmetic mean method of finding the optimal single- replacement- age of an ...

CANDU-PHW fuel channel replacement experience

International Nuclear Information System (INIS)

Dunn, J.T.; Kakaria, B.K.

1982-09-01

One of the main characteristics of the CANDU pressurized heavy water reactor is the use of pressure tubes rather than one large pressure vessel to contain the fuel and coolant. This provides an inherent design capability to permit their replacement in an expeditious manner, without seriously affecting the high capacity factors of the reactor units. Of th eight Ontario Hydro commercial nuclear generating units, the lifetime performance places seven of them (including two that have had some of their fuel channels replaced), in the top ten positions in the world's large nuclear-electric unit performance ranking. Pressure tube cracks in the rolled joint region have resulted in 70 fuel channels being replaced in three reactor units, the latest being at the Bruce Nuclear Generating Station 'A', Unit 2 in February 1982. The rolled joint design and rolling procedures have been modified to eliminate this problem on CANDU units subsequent to Bruce 'A'. This paper describes the CANDU pressure tube performance history and expectations, and the tooling and procedures used to carry out the fuel channel replacement

Exploring the speed and performance of molecular replacement with AMPLE using QUARK ab initio protein models

Energy Technology Data Exchange (ETDEWEB)

Keegan, Ronan M. [STFC Rutherford Appleton Laboratory, Didcot OX11 0FA (United Kingdom); Bibby, Jaclyn; Thomas, Jens [University of Liverpool, Liverpool L69 7ZB (United Kingdom); Xu, Dong [Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037 (United States); Zhang, Yang [University of Michigan, Ann Arbor, MI 48109 (United States); Mayans, Olga [University of Liverpool, Liverpool L69 7ZB (United Kingdom); Winn, Martyn D. [Science and Technology Facilities Council Daresbury Laboratory, Warrington WA4 4AD (United Kingdom); Rigden, Daniel J., E-mail: drigden@liv.ac.uk [University of Liverpool, Liverpool L69 7ZB (United Kingdom); STFC Rutherford Appleton Laboratory, Didcot OX11 0FA (United Kingdom)

2015-02-01

Two ab initio modelling programs solve complementary sets of targets, enhancing the success of AMPLE with small proteins. AMPLE clusters and truncates ab initio protein structure predictions, producing search models for molecular replacement. Here, an interesting degree of complementarity is shown between targets solved using the different ab initio modelling programs QUARK and ROSETTA. Search models derived from either program collectively solve almost all of the all-helical targets in the test set. Initial solutions produced by Phaser after only 5 min perform surprisingly well, improving the prospects for in situ structure solution by AMPLE during synchrotron visits. Taken together, the results show the potential for AMPLE to run more quickly and successfully solve more targets than previously suspected.

Transcatheter Aortic Valve Replacement in Europe

DEFF Research Database (Denmark)

Mylotte, Darren; Osnabrugge, Ruben L J; Windecker, Stephan

2013-01-01

The authors sought to examine the adoption of transcatheter aortic valve replacement (TAVR) in Western Europe and investigate factors that may influence the heterogeneous use of this therapy.......The authors sought to examine the adoption of transcatheter aortic valve replacement (TAVR) in Western Europe and investigate factors that may influence the heterogeneous use of this therapy....

Aeronautical Information System Replacement -

Data.gov (United States)

Department of Transportation — Aeronautical Information System Replacement is a web-enabled, automation means for the collection and distribution of Service B messages, weather information, flight...

Fleet replacement modeling : final report, July 2009.

Science.gov (United States)

2009-07-01

This project focused on two interrelated areas in equipment replacement modeling for fleets. The first area was research-oriented and addressed a fundamental assumption in engineering economic replacement modeling that all assets providing a similar ...

Nuclear Proliferation: A Historical Overview

Science.gov (United States)

2008-03-01

Soviet Union in 1991, Kazakhstan inherited approximately 1,410 nuclear warheads and the Semipalatinsk nuclear weapons test site . This placed Kazakhstan...Soviet Union, Kazakhstan inherited approximately 1,410 nuclear warheads and the Semipalatinsk nuclear weapons test site . See Mark D. Skootsky, “An...construction of a nuclear test site . This development moved Brazil into the Modest Weapons Potential category. In 1979 the Pilot Uranium Enrichment Plant

Conceptual Design Plan SM-43 Replacement Project

Energy Technology Data Exchange (ETDEWEB)

University of California, Los Alamos National Laboratory, SCC Project Office

2000-11-01

The Los Alamos National Laboratory Conceptual Design Plan for the SM-43 Replacement Project outlines plans for replacing the SM-43 Administration Building. Topics include the reasons that replacement is considered a necessity; the roles of the various project sponsors; and descriptions of the proposed site and facilities. Also covered in this proposal is preliminary information on the project schedule, cost estimates, acquisition strategy, risk assessment, NEPA strategy, safety strategy, and safeguards and security. Spreadsheets provide further detail on space requirements, project schedules, and cost estimates.

Apparatus for fuel replacement

International Nuclear Information System (INIS)

Imada, Takahiko.

1974-01-01

Object: To support a telescope mast such that no deforming load is applied to it even during massive vibration, it is held fixed at the time of fuel replacement to permit satisfactory remote control operation by automatic operation. Structure: The body of the fuel replacement apparatus is provided with telescope mast fixing means comprising a slide base supported for reciprocal movement with respect to a telescope mast, an operating arm pivoted at the slide base, a wrist member mounted on the free end of the operating arm and an engagement member for restricting the slide base and operating arm at the time of loading and unloading the fuel. When loading and unloading the fuel, the slide base and operating arm are restrained by the engagement member to reliably restrict the vibration of the telescope mast. When the fuel replacement apparatus is moved, the means provided on the operating arm is smoothly displaced to follow the swing (vibration) of the telescope mast to prevent the deforming load from being applied to the support portion or other areas. The wrist member supports the telescope mast such that it can be rotated while restraining movement in the axial direction, and it is provided with revolution drive means for rotating the telescope mast under remote control. (Kamimura, M.)

Mitochondrial replacement techniques: egg donation, genealogy and eugenics.

Science.gov (United States)

Palacios-González, César

2016-03-01

Several objections against the morality of researching or employing mitochondrial replacement techniques have been advanced recently. In this paper, I examine three of these objections and show that they are found wanting. First I examine whether mitochondrial replacement techniques, research and clinical practice, should not be carried out because of possible harms to egg donors. Next I assess whether mitochondrial replacement techniques should be banned because they could affect the study of genealogical ancestry. Finally, I examine the claim that mitochondrial replacement techniques are not transferring mitochondrial DNA but nuclear DNA, and that this should be prohibited on ethical grounds.

Joint replacement in Zambia: A review of Hip & Knee Replacement ...

African Journals Online (AJOL)

Methods: Data captured by the different variables entered into the Joint Register covering the pre-op, intra-op and post-op period of all total hip and knee replacement surgery done at the ZIOH from 1998 to 2010 was entered into a spreadsheet after verification with individual patient medical records. This was then imported ...

Cadmium plating replacements

Energy Technology Data Exchange (ETDEWEB)

Nelson, M.J.; Groshart, E.C.

1995-03-01

The Boeing Company has been searching for replacements to cadmium plate. Two alloy plating systems seem close to meeting the needs of a cadmium replacement. The two alloys, zinc-nickel and tin-zinc are from alloy plating baths; both baths are neutral pH. The alloys meet the requirements for salt fog corrosion resistance, and both alloys excel as a paint base. Currently, tests are being performed on standard fasteners to compare zinc-nickel and tin-zinc on threaded hardware where cadmium is heavily used. The Hydrogen embrittlement propensity of the zinc-nickel bath has been tested, and just beginning for the tin-zinc bath. Another area of interest is the electrical properties on aluminum for tin-zinc and will be discussed. The zinc-nickel alloy plating bath is in production in Boeing Commercial Airplane Group for non-critical low strength steels. The outlook is promising that these two coatings will help The Boeing Company significantly reduce its dependence on cadmium plating.

Renal replacement therapy in healthy adult horses.

Science.gov (United States)

Wong, D M; Witty, D; Alcott, C J; Sponseller, B A; Wang, C; Hepworth, K

2013-01-01

Renal replacement therapy (RRT) has been implemented extensively in people to facilitate recovery from acute renal failure (ARF). RRT has not been explored in horses, but might provide a further treatment option in horses with ARF. To investigate efficacy and safety of RRT in horses. Five healthy adult horses. A prospective study was performed on horses restrained in stocks and intravenously connected to a commercial RRT machine to allow continuous venovenous hemodiafiltration to be performed for 6 hours. The RRT machine was set at the following flow rates: blood flow rate 250 mL/min; dialysate rate 3,000 mL/h; prefilter replacement pump 3,000 mL/h; and postfilter replacement pump rate 2,000 mL/h. Balanced electrolyte solution was used as dialysate and replacement fluid. Heart rate, respiratory rate, body temperature, direct arterial blood pressure, urine output, and various clinicopathologic parameters were measured over the study period. Renal replacement therapy was successfully performed in horses, resulting in a mean creatinine clearance of 0.127 mL/kg/min (68.9 mL/min) and urea reduction ratio of 24%. No adverse effects were detected although a significant decrease in rectal temperature was observed (P ≤ .007). A significant increase in serum phosphorus (P ≤ .001) and decrease in BUN (P replacement therapy can safely and effectively be used in adult horses. Copyright © 2013 by the American College of Veterinary Internal Medicine.

Avascular necrosis of bone complicating corticosteroid replacement therapy.

OpenAIRE

Williams, P L; Corbett, M

1983-01-01

Two patients who developed widespread severe avascular necrosis of bone while on steroid replacement therapy are described. One, a diabetic, underwent yttrium-90 pituitary ablation for retinopathy and developed avascular necrosis within 18 months of starting prednisolone. The other, who had Addison's disease, developed avascular necrosis within 14 months of starting cortisol replacement therapy. Both cases came to bilateral total hip replacement.

THE AGGREGATE IMPLICATIONS OF MACHINE REPLACEMENT: THEORY AND EVIDENCE

OpenAIRE

John Haltiwanger; Russell Cooper

1992-01-01

The authors study an economy in which producers incur resource costs to replace depreciated machines. The process of costly replacement and depreciation creates endogenous fluctuations in productivity, employment, and output of a single producer. The authors explore the spillover effects of machine replacement on other sectors of the economy and provide conditions for synchronized machine replacement by multiple independent producers. The implications of their model are generally consistent w...

Feed water distribution pipe replacement at Loviisa NPP

Energy Technology Data Exchange (ETDEWEB)

Savolainen, S.; Elsing, B. [Imatran Voima Loviisa NPP (Finland)

1995-12-31

Imatran Voima Oy operates two WWER-440 reactors. Unit 1 has been operating since 1977 and unit 2 since 1981. First damages of feed water distribution (FWD) pipe were observed in 1989. The FWD-pipe T-connection had suffered from severe erosion corrosion damages. Similar damages have been been found also in other WWER-440 type NPPs. In 1989 the nozzles of the steam generator YB11 were inspected. No signs of the damages or signs of erosion were detected. The first damaged nozzles were found in 1992 in steam generators of both units. In 1992 it was started studying different possibilities to either repair or replace the damaged FWD-pipes. Due to the difficult conditions for repairing the damaged nozzles it was decided to study different FWD-pipe constructions. In 1991 two new feedwater distributors had been implemented at Dukovany NPP designed by Vitckovice company. Additionally OKB Gidropress had presented their design for new collector. In spring 1994 all the six steam generators of Rovno NPP unit 1 were replaced with FWD-pipes designed by OKB Gidropress. After the implementation an experimental program with the new systems was carried out. Due to the successful experiments at Rovno NPP Unit 1 it was decided to implement `Gidropress solution` during 1994 refueling outage into the steam generator YB52 at Loviisa 2. The object of this paper is to discuss the new FWD-pipe and its effects on the plant safety during normal and accident conditions. (orig.).

Feed water distribution pipe replacement at Loviisa NPP

Energy Technology Data Exchange (ETDEWEB)

Savolainen, S; Elsing, B [Imatran Voima Loviisa NPP (Finland)

1996-12-31

Imatran Voima Oy operates two WWER-440 reactors. Unit 1 has been operating since 1977 and unit 2 since 1981. First damages of feed water distribution (FWD) pipe were observed in 1989. The FWD-pipe T-connection had suffered from severe erosion corrosion damages. Similar damages have been been found also in other WWER-440 type NPPs. In 1989 the nozzles of the steam generator YB11 were inspected. No signs of the damages or signs of erosion were detected. The first damaged nozzles were found in 1992 in steam generators of both units. In 1992 it was started studying different possibilities to either repair or replace the damaged FWD-pipes. Due to the difficult conditions for repairing the damaged nozzles it was decided to study different FWD-pipe constructions. In 1991 two new feedwater distributors had been implemented at Dukovany NPP designed by Vitckovice company. Additionally OKB Gidropress had presented their design for new collector. In spring 1994 all the six steam generators of Rovno NPP unit 1 were replaced with FWD-pipes designed by OKB Gidropress. After the implementation an experimental program with the new systems was carried out. Due to the successful experiments at Rovno NPP Unit 1 it was decided to implement `Gidropress solution` during 1994 refueling outage into the steam generator YB52 at Loviisa 2. The object of this paper is to discuss the new FWD-pipe and its effects on the plant safety during normal and accident conditions. (orig.).

Defining waste acceptance criteria for the Hanford Replacement Cross-Site Transfer System

International Nuclear Information System (INIS)

Hudson, J.D.

1996-04-01

This document provides a methodology for defining waste acceptance criteria for the Hanford Replacement Cross-Site Transfer System (RCSTS). This methodology includes characterization, transport analysis, and control. A framework is described for each of these functions. A tool was developed for performing the calculations associated with the transport analysis. This tool, a worksheet that is available in formats acceptable for a variety of PC spreadsheet programs, enables a comparison of the pressure required to transport a given slurry at a rate that particulate suspension is maintained to the pressure drop available from the RCSTS

Optimal timing for intravascular administration set replacement.

Science.gov (United States)

Ullman, Amanda J; Cooke, Marie L; Gillies, Donna; Marsh, Nicole M; Daud, Azlina; McGrail, Matthew R; O'Riordan, Elizabeth; Rickard, Claire M

2013-09-15

The tubing (administration set) attached to both venous and arterial catheters may contribute to bacteraemia and other infections. The rate of infection may be increased or decreased by routine replacement of administration sets. This review was originally published in 2005 and was updated in 2012. The objective of this review was to identify any relationship between the frequency with which administration sets are replaced and rates of microbial colonization, infection and death. We searched The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2012, Issue 6), MEDLINE (1950 to June 2012), CINAHL (1982 to June 2012), EMBASE (1980 to June 2012), reference lists of identified trials and bibliographies of published reviews. The original search was performed in February 2004. We also contacted researchers in the field. We applied no language restriction. We included all randomized or controlled clinical trials on the frequency of venous or arterial catheter administration set replacement in hospitalized participants. Two review authors assessed all potentially relevant studies. We resolved disagreements between the two review authors by discussion with a third review author. We collected data for seven outcomes: catheter-related infection; infusate-related infection; infusate microbial colonization; catheter microbial colonization; all-cause bloodstream infection; mortality; and cost. We pooled results from studies that compared different frequencies of administration set replacement, for instance, we pooled studies that compared replacement ≥ every 96 hours versus every 72 hours with studies that compared replacement ≥ every 48 hours versus every 24 hours. We identified 26 studies for this updated review, 10 of which we excluded; six did not fulfil the inclusion criteria and four did not report usable data. We extracted data from the remaining 18 references (16 studies) with 5001 participants: study designs included neonate and adult

Some economic aspects of steam generator replacements in nuclear power plants

International Nuclear Information System (INIS)

Lebegner, J.

1995-01-01

The steam generator replacements performed over last decade (about 25 replacements until now), indicate trends towards improved techniques, shorter schedules and reduced total exposure and total costs. The goal of this paper is to give a worldwide review of SG replacement experience with accent on the economic aspect of the SG replacement. The main information about carried out replacements will be presented: cost, schedules, exposures, SG supplier and type, date of replacement, etc. Furthermore, the paper will contain the list of planned steam generator replacements in Europe, Japan and US future replacement plans. Finally, some of NPPs will be described whose initial nominal power has been increased along with SG replacement. (author)

Replacing fuel alignment in Germany

International Nuclear Information System (INIS)

Poetz, F.; Kalthoff, W.

1991-01-01

Up to the end of 1989 varying numbers of broken fuel alignment pins were detected in several German PWRs (80 broken pins in all). The distribution of these broken pins over the core cross-section was more or less random. The problem was due to the stress corrosion cracking of the pin material and was restricted to individual pins. It was concluded that all fuel alignment pins made of Inconel X-750 should be replaced. The development of a new pin, more resistant to intergranular stress corrosion, and the replacement technique are outlined. (author)

HST Replacement Battery Initial Performance

Science.gov (United States)

Krol, Stan; Waldo, Greg; Hollandsworth, Roger

2009-01-01

The Hubble Space Telescope (HST) original Nickel-Hydrogen (NiH2) batteries were replaced during the Servicing Mission 4 (SM4) after 19 years and one month on orbit.The purpose of this presentation is to highlight the findings from the assessment of the initial sm4 replacement battery performance. The batteries are described, the 0 C capacity is reviewed, descriptions, charts and tables reviewing the State Of Charge (SOC) Performance, the Battery Voltage Performance, the battery impedance, the minimum voltage performance, the thermal performance, the battery current, and the battery system recharge ratio,

Insurance for replacement power costs

International Nuclear Information System (INIS)

Cleaver, A.

1980-01-01

Although careful consideration is given to insurance against physical damage to plant and equipment, little thought is given to the costs that will be incurred in replacing the power that is lost while a relatively efficient system is out of action. The results of an investigation carried out for a generating authority with an installed capacity of about 3000 MW is given. Replacement power costs for different cases of severity of damage range from Pound1.17m per month for damage to central services taking out all four units. (author)

Proving deadlock freedom of logic programs with dynamic scheduling

NARCIS (Netherlands)

E. Marchiori; F. Teusink (Frank)

1996-01-01

textabstractIn increasingly many logic programming systems, the Prolog left to right selection rule has been replaced with dynamic selection rules, that select an atom of a query among those satisfying suitable conditions. These conditions describe the form of the arguments of every program

Studies on the replacement policies in dairy cattle II.Optimum policy and influence of changes in production and prices

NARCIS (Netherlands)

Arendonk, van J.A.M.

1985-01-01

A dynamic programming model was developed to determine the optimum replacement policy of dairy cows. In the model cows were described in terms of lactation number, stage of lactation and the level of milk production during the previous and present lactations. The objective in determining the optimum

Replacing Recipe Realism

OpenAIRE

Saatsi, J

2017-01-01

Many realist writings exemplify the spirit of ‘recipe realism’. Here I characterise recipe realism, challenge it, and propose replacing it with ‘exemplar realism’. This alternative understanding of realism is more piecemeal, robust, and better in tune with scientists’ own attitude towards their best theories, and thus to be preferred.

Estimating the shear strength of concrete with coarse aggregate replacement

OpenAIRE

Folagbade Olusoga Peter ORIOLA; George MOSES; Jacob Oyeniyi AFOLAYAN; John Engbonye SANI

2017-01-01

For economic, environmental and practical reasons, it is desirable to replace the constituents of concrete with wastes and cheaper alternative materials. However, it is best when such replacements are done at optimum replacement levels. In view of this, a laboratory investigative test was carried out to evaluate the shear strength of concrete with coarse aggregate replacement by Coconut Shell and by Waste Rubber Tyre. The coarse aggregate replacement was done at recommended optimum proportion...

Differences in the stress distribution in the distal femur between patellofemoral joint replacement and total knee replacement: a finite element study

Directory of Open Access Journals (Sweden)

van Jonbergen Hans-Peter W

2012-06-01

Full Text Available Abstract Background Patellofemoral joint replacement is a successful treatment option for isolated patellofemoral osteoarthritis. However, results of later conversion to total knee replacement may be compromised by periprosthetic bone loss. Previous clinical studies have demonstrated a decrease in distal femoral bone mineral density after patellofemoral joint replacement. It is unclear whether this is due to periprosthetic stress shielding. The main objective of the current study was to evaluate the stress shielding effect of prosthetic replacement with 2 different patellofemoral prosthetic designs and with a total knee prosthesis. Methods We developed a finite element model of an intact patellofemoral joint, and finite element models of patellofemoral joint replacement with a Journey PFJ prosthesis, a Richards II prosthesis, and a Genesis II total knee prosthesis. For each of these 4 finite element models, the average Von Mises stress in 2 clinically relevant regions of interest were evaluated during a simulated squatting movement until 120 degrees of flexion. Results During deep knee flexion, in the anterior region of interest, the average Von Mises stress with the Journey PFJ design was comparable to the physiological knee, while reduced by almost 25% for both the Richards II design and the Genesis II total knee joint replacement design. The average Von Mises stress in the supracondylar region of interest was similar for both patellofemoral prosthetic designs and the physiological model, with slightly lower stress for the Genesis II design. Conclusions Patellofemoral joint replacement results in periprosthetic stress-shielding, although to a smaller degree than in total knee replacement. Specific patellofemoral prosthetic design properties may result in differences in femoral stress shielding.

Differences in the stress distribution in the distal femur between patellofemoral joint replacement and total knee replacement: a finite element study

Science.gov (United States)

2012-01-01

Background Patellofemoral joint replacement is a successful treatment option for isolated patellofemoral osteoarthritis. However, results of later conversion to total knee replacement may be compromised by periprosthetic bone loss. Previous clinical studies have demonstrated a decrease in distal femoral bone mineral density after patellofemoral joint replacement. It is unclear whether this is due to periprosthetic stress shielding. The main objective of the current study was to evaluate the stress shielding effect of prosthetic replacement with 2 different patellofemoral prosthetic designs and with a total knee prosthesis. Methods We developed a finite element model of an intact patellofemoral joint, and finite element models of patellofemoral joint replacement with a Journey PFJ prosthesis, a Richards II prosthesis, and a Genesis II total knee prosthesis. For each of these 4 finite element models, the average Von Mises stress in 2 clinically relevant regions of interest were evaluated during a simulated squatting movement until 120 degrees of flexion. Results During deep knee flexion, in the anterior region of interest, the average Von Mises stress with the Journey PFJ design was comparable to the physiological knee, while reduced by almost 25% for both the Richards II design and the Genesis II total knee joint replacement design. The average Von Mises stress in the supracondylar region of interest was similar for both patellofemoral prosthetic designs and the physiological model, with slightly lower stress for the Genesis II design. Conclusions Patellofemoral joint replacement results in periprosthetic stress-shielding, although to a smaller degree than in total knee replacement. Specific patellofemoral prosthetic design properties may result in differences in femoral stress shielding. PMID:22704638

Strategic vehicle fleet management - the replacement problem

Directory of Open Access Journals (Sweden)

Adam Redmer

2016-03-01

Full Text Available Background: Fleets constitute the most important production means in transportation. Their appropriate management is crucial for all companies having transportation duties. The paper is the third one of a series of three papers that the author dedicates to the strategic vehicle fleet management topic. Material and methods: The paper discusses ways of building replacement strategies for companies' fleets of vehicles. It means deciding for how long to exploit particular vehicles in a fleet (the fleet replacement problem - FR. The essence of this problem lies in the minimization of vehicle / fleet exploitation costs by balancing ownership and utilization costs and taking into account budget limitations. In the paper an original mathematical model (an optimization method allowing for the FR analysis is proposed. Results: An application of the proposed optimization method in a real-life decision situation (the case study within the Polish environment and the obtained solution are presented. The solution shows that there exist optimal exploitation periods of particular vehicles in a fleet. However, combination of them gives a replacement plan for an entire fleet violating budget constraints. But it is possible to adjust individual age to replacement of particular vehicles to fulfill budget constraints without losing economical optimality of a developed replacement plan for an entire fleet. Conclusions: The paper is the last one of a series of three papers that the author dedicated to the strategic vehicle fleet management topic including the following managerial decision problems: MAKE-or-BUY, sizing / composition and replacement.

48 CFR 908.7112 - Materials handling equipment replacement standards.

Science.gov (United States)

2010-10-01

... equipment replacement standards. 908.7112 Section 908.7112 Federal Acquisition Regulations System DEPARTMENT... Special Items 908.7112 Materials handling equipment replacement standards. Materials handling equipment shall be purchased for replacement purposes in accordance with the standards in FPMR 41 CFR 101-25.405...

Postmenopausal hormone replacement therapy--clinical implications

DEFF Research Database (Denmark)

Ravn, S H; Rosenberg, J; Bostofte, E

1994-01-01

The menopause is defined as cessation of menstruation, ending the fertile period. The hormonal changes are a decrease in progesterone level, followed by a marked decrease in estrogen production. Symptoms associated with these hormonal changes may advocate for hormonal replacement therapy....... This review is based on the English-language literature on the effect of estrogen therapy and estrogen plus progestin therapy on postmenopausal women. The advantages of hormone replacement therapy are regulation of dysfunctional uterine bleeding, relief of hot flushes, and prevention of atrophic changes...... in the urogenital tract. Women at risk of osteoporosis will benefit from hormone replacement therapy. The treatment should start as soon after menopause as possible and it is possible that it should be maintained for life. The treatment may be supplemented with extra calcium intake, vitamin D, and maybe calcitonin...

Advanced, enhanced HEX program for PIXE

International Nuclear Information System (INIS)

Lipworth, A.D.; Annegarn, H.J.; Kneen, M.A.

1993-01-01

The REX code and subsequent HEX code, originating at Florida State University, have been extensively used for PIXE spectra fitting. In 1989 we produce a renovated HEX package: WITS-HEX, enabling the original Fortran program to be more accessible to the PIXE community. We modernised the user interface by replacing the batch mode of operation with an integrated, menu-driven environment. We added the ability to edit support data files from within the program, provided detailed feedback during the fitting process and enhanced spectral plots using high resolution colour graphics. Our prototype also permitted the inclusion of many more peaks and absorption coefficients into the element library than the original HEX, permitting a more extensive element request list to be used during the fitting operation. We have now completed the second phase of the renewal of HEX. The man-machine interface has been upgraded to conform to the IBM SAA Common User Access (CUA) standard. This eliminated several of the sequential (modal) human-computer dialogues, replacing them with a single parallel system. The support utility used in WITS-HEX to convert the binary format of spectra captured using foreign data acquisition systems has been replaced by code to directly access data in ASCII format. The program is now equipped with context-sensitive help and a tutorial. The polynomial background mode has been supplemented by a digital filter model, eliminating the associated instability from the fitting process and other spectral features modelled. The program has been validated by comparing results with those obtained from the former versions: WITS-HEX and HEX. A demonstration version is available on request for evaluation purposes. (orig.)

THE REPLACEMENT-RENEWAL OF INDUSTRIAL EQUIPMENTS. THE MAPI FORMULAS

Directory of Open Access Journals (Sweden)

Meo Colombo Carlotta

2010-07-01

Full Text Available Since the production has been found to be an economical means for satisfying human wants, this process requires a complex industrial organization together with a large investment in equipments, plants and productive systems. These productive systems are employed to alter the physical environment and create consumer goods. As a result, they are consumed or become obsolete, inadequate, or otherwise candidates for replacement. When replacement is being considered, two assets must be evaluated: the present asset, the defender and its potential replacement, the challenger. Since the success of an industrial organization depends upon profit, replacement should generally occur if an economic advantage will result. Whatever the reason leading to the consideration of replacement, the analysis and decisions must be based upon estimates of what will occur in the future. In this paper we present the Mapi algorithm as a procedure for evaluating investments or for analyzing replacement opportunities.

A useful framework for optimal replacement models

International Nuclear Information System (INIS)

Aven, Terje; Dekker, Rommert

1997-01-01

In this note we present a general framework for optimization of replacement times. It covers a number of models, including various age and block replacement models, and allows a uniform analysis for all these models. A relation to the marginal cost concept is described

Adjacent level effects of bi level disc replacement, bi level fusion and disc replacement plus fusion in cervical spine--a finite element based study.

Science.gov (United States)

Faizan, Ahmad; Goel, Vijay K; Biyani, Ashok; Garfin, Steven R; Bono, Christopher M

2012-03-01

Studies delineating the adjacent level effect of single level disc replacement systems have been reported in literature. The aim of this study was to compare the adjacent level biomechanics of bi-level disc replacement, bi-level fusion and a construct having adjoining level disc replacement and fusion system. In total, biomechanics of four models- intact, bi level disc replacement, bi level fusion and fusion plus disc replacement at adjoining levels- was studied to gain insight into the effects of various instrumentation systems on cranial and caudal adjacent levels using finite element analysis (73.6N+varying moment). The bi-level fusion models are more than twice as stiff as compared to the intact model during flexion-extension, lateral bending and axial rotation. Bi-level disc replacement model required moments lower than intact model (1.5Nm). Fusion plus disc replacement model required moment 10-25% more than intact model, except in extension. Adjacent level motions, facet loads and endplate stresses increased substantially in the bi-level fusion model. On the other hand, adjacent level motions, facet loads and endplate stresses were similar to intact for the bi-level disc replacement model. For the fusion plus disc replacement model, adjacent level motions, facet loads and endplate stresses were closer to intact model rather than the bi-level fusion model, except in extension. Based on our finite element analysis, fusion plus disc replacement procedure has less severe biomechanical effects on adjacent levels when compared to bi-level fusion procedure. Bi-level disc replacement procedure did not have any adverse mechanical effects on adjacent levels. Copyright © 2011 Elsevier Ltd. All rights reserved.

A comparison of minimally invasive and standard aortic valve replacement.

Science.gov (United States)

Stoliński, Jarosław; Plicner, Dariusz; Grudzień, Grzegorz; Wąsowicz, Marcin; Musiał, Robert; Andres, Janusz; Kapelak, Bogusław

2016-10-01

The study objective was to compare aortic valve replacement through a right anterior minithoracotomy with aortic valve replacement through a median sternotomy. With propensity score matching, we selected 211 patients after aortic valve replacement through a right anterior minithoracotomy and 211 patients after aortic valve replacement who underwent operation between January 2010 and December 2013. Perioperative outcomes were analyzed, and multivariable logistic regression analysis of risk factors of postoperative morbidity was performed. For propensity score-matched patients, hospital mortality was 1.0% in the aortic valve replacement through a right anterior minithoracotomy group and 1.4% in the aortic valve replacement group (P = 1.000). Stroke occurred in 0.5% versus 1.4% (P = .615), myocardial infarction occurred in 1.4% versus 1.9% (P = 1.000), and new onset of atrial fibrillation occurred in 12.8% versus 24.2% (P = .003) of patients in the aortic valve replacement through a right anterior minithoracotomy and aortic valve replacement groups, respectively. Postoperative drainage was 353.5 ± 248.6 mL versus 544.3 ± 324.5 mL (P replacement through a right anterior minithoracotomy and aortic valve replacement groups, respectively. Mediastinitis occurred in 2.8% of patients after aortic valve replacement and in 0.0% of patients after aortic valve replacement through a right anterior minithoracotomy surgery (P = .040). Intensive care unit stay (1.3 ± 1.2 days vs 2.6 ± 2.6 days) and hospital stay (5.7 ± 1.6 days vs 8.7 ± 4.4 days) were statistically significantly shorter in the aortic valve replacement through a right anterior minithoracotomy group. Aortic valve replacement through a right anterior minithoracotomy surgery resulted in reduced postoperative morbidity (odds ratio, 0.4; P replacement through a right anterior minithoracotomy surgery resulted in a reduced infection rate, diminished postoperative bleeding and blood

Rehabilitation after total joint replacement: a scoping study.

Science.gov (United States)

L Snell, Deborah; Hipango, Julia; Sinnott, K Anne; Dunn, Jennifer A; Rothwell, Alastair; Hsieh, C Jean; DeJong, Gerben; Hooper, Gary

2018-07-01

The evidence supporting rehabilitation after joint replacement, while vast, is of variable quality making it difficult for clinicians to apply the best evidence to their practice. We aimed to map key issues for rehabilitation following joint replacement, highlighting potential avenues for new research. We conducted a scoping study including research published between January 2013 and December 2016, evaluating effectiveness of rehabilitation following hip and knee total joint replacement. We reviewed this work in the context of outcomes described from previously published research. Thirty individual studies and seven systematic reviews were included, with most research examining the effectiveness of physiotherapy-based exercise rehabilitation after total knee replacement using randomized control trial methods. Rehabilitation after hip and knee replacement whether carried out at the clinic or monitored at home, appears beneficial but type, intensity and duration of interventions were not consistently associated with outcomes. The burden of comorbidities rather than specific rehabilitation approach may better predict rehabilitation outcome. Monitoring of recovery and therapeutic attention appear important but little is known about optimal levels and methods required to maximize outcomes. More work exploring the role of comorbidities and key components of therapeutic attention and the therapy relationship, using a wider range of study methods may help to advance the field. Implications for Rehabilitation Physiotherapy-based exercise rehabilitation after total hip replacement and total knee replacement, whether carried out at the clinic or monitored at home, appears beneficial. Type, intensity, and duration of interventions do not appear consistently associated with outcomes. Monitoring a patient's recovery appears to be an important component. The available research provides limited guidance regarding optimal levels of monitoring needed to achieve gains following hip

21 CFR 870.3710 - Pacemaker repair or replacement material.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Pacemaker repair or replacement material. 870.3710... (CONTINUED) MEDICAL DEVICES CARDIOVASCULAR DEVICES Cardiovascular Prosthetic Devices § 870.3710 Pacemaker repair or replacement material. (a) Identification. A pacemaker repair or replacement material is an...

Tool Inventory and Replacement

Science.gov (United States)

Bear, W. Forrest

1976-01-01

Vocational agriculture teachers are encouraged to evaluate curriculum offerings, the new trends in business and industry, and develop a master tool purchase and replacement plan over a 3- to 5-year period. (HD)

Multi-stage type replacing method of iodine filter

International Nuclear Information System (INIS)

Kitamura, Masao; Kamiya, Kunio.

1976-01-01

Object: To effectively replace a filter into a removing device of radioactive impurities used in ventilation and air conditioning system or the like in an atomic power plant. Structure: A plurality of elements of a filter are arranged in series relative to fluid. In the first replacement, an ante-filter-element on inlet side of fluid is removed, and a post-filter-element is repositioned to that position of the ante-element. Then, a fresh element is newly mounted on that position of the post-element. Replacement after the second time may be effected by repeating the operation noted above. With this arrangement, the minimal value of collection efficiency at replacement of filter may be increased. (Ikeda, J.)

Functional Programming in R

DEFF Research Database (Denmark)

Mailund, Thomas

Master functions and discover how to write functional programs in R. In this book, you'll make your functions pure by avoiding side-effects; you’ll write functions that manipulate other functions, and you’ll construct complex functions using simpler functions as building blocks. In Functional...... Programming in R, you’ll see how we can replace loops, which can have side-effects, with recursive functions that can more easily avoid them. In addition, the book covers why you shouldn't use recursion when loops are more efficient and how you can get the best of both worlds. Functional programming...... is a style of programming, like object-oriented programming, but one that focuses on data transformations and calculations rather than objects and state. Where in object-oriented programming you model your programs by describing which states an object can be in and how methods will reveal or modify...

Functional Programming in R

DEFF Research Database (Denmark)

Mailund, Thomas

2017-01-01

Master functions and discover how to write functional programs in R. In this book, you'll make your functions pure by avoiding side-effects; you’ll write functions that manipulate other functions, and you’ll construct complex functions using simpler functions as building blocks. In Functional...... Programming in R, you’ll see how we can replace loops, which can have side-effects, with recursive functions that can more easily avoid them. In addition, the book covers why you shouldn't use recursion when loops are more efficient and how you can get the best of both worlds. Functional programming...... is a style of programming, like object-oriented programming, but one that focuses on data transformations and calculations rather than objects and state. Where in object-oriented programming you model your programs by describing which states an object can be in and how methods will reveal or modify...

Property Assessment of Sponge Cake Added with Egg Replacer

OpenAIRE

Yaqiang He; Linlin Wang; Qian Lu

2015-01-01

Chicken egg which is always used in sponge cake production is likely to deteriorate during storage or transportation. This weakness prevents the wide use of chicken egg in sponge cake making. In order to solve this problem, egg replacer has been developed. In this study, effect of egg replacer on the property of sponge cake was analyzed. The result indicated egg replacer could improve the yield rate and specific volume of sponge cake. However, high content of egg replacer would negatively imp...

Hip joint replacement - slideshow

Science.gov (United States)

... this page: //medlineplus.gov/ency/presentations/100006.htm Hip joint replacement - series—Normal anatomy To use the ... to slide 5 out of 5 Overview The hip joint is made up of two major parts: ...

Principles of human joint replacement design and clinical application

CERN Document Server

Buechel, Frederick F

2015-01-01

This book is written for the users and designers of joint replacements. In its second extended edition it conveys to the reader the knowledge accumulated by the authors during their forty year effort on the development of replacement devices for the lower limb for the purpose of aiding the reader in their design and evaluation of joint replacement devices. The early chapters describe the engineering, scientific and medical principles needed for replacement joint evaluation. One must understand the nature and performance of the materials involved and their characteristics in vivo, i.e. the response of the body to implant materials. It is also essential to understand the response of the implants to applied loading and motion, particularly in the hostile physiological environment. A chapter describes the design methodology now required for joint replacement in the USA and EU countries. The remaining chapters provide a history of joint replacement, an evaluation of earlier and current devices and sample case hist...

Principles of Human Joint Replacement Design and Clinical Application

CERN Document Server

Buechel, Frederick F

2012-01-01

Drs. Buechel, an orthopaedic surgeon, and Pappas, a professor of Mechanical Engineering, are the designers of several successful joint replacement systems. The most well-known of these is the pioneering LCS knee replacement. They have written this book for the users and designers of joint replacements. It is an attempt to convey to the reader the knowledge accumulated by the authors during their thirty five year effort on the development of replacement devices for the lower limb for the purpose of aiding the reader in their design and evaluation of joint replacement devices. The early chapters describe the engineering, scientific and medical principles needed for replacement joint evaluation. One must understand the nature and performance of the materials involved and their characteristics in vivo, i.e. the response of the body to implant materials. It is also essential to understand the response of the implants to applied loading and motion, particularly in the hostile physiological environment. A chapter de...

Mitochondrial replacement techniques: egg donation, genealogy and eugenics

OpenAIRE

Palacios-Gonz?lez, C?sar

2016-01-01

Several objections against the morality of researching or employing mitochondrial replacement techniques have been advanced recently. In this paper, I examine three of these objections and show that they are found wanting. First I examine whether mitochondrial replacement techniques, research and clinical practice, should not be carried out because of possible harms to egg donors. Next I assess whether mitochondrial replacement techniques should be banned because they could affect the study o...

Steam generator replacement from ALARA aspects

International Nuclear Information System (INIS)

Terry, I.; Breznik, B.

2003-01-01

This paper is going to consider radiological related parameters important for steam generator replacement (SGR) implementation. These parameters are identified as ALARA related parameters, owner-contractor relationship, planning, health physics with logistic services, and time required for the replacement. ALARA related parameters such as source or initial dose rate and plant system configuration define the initial conditions for the planning. There is room to optimise work planning. managerial procedures and also the staff during the implementation phase. The overview of these general considerations is based on the following background: using internationally available data and the experience of one of the vendors, i.e. Siemens-Framatome, and management experience of SG replacement which took place at Krsko NPP in the spring of 2000. Generally plant decisions on maintenance or repair procedures under radiation conditions take into account ALARA considerations. But in the main it is difficult to adjudge the results of an ALARA study, usually in the form of a collective dose estimate, because a comparison standard is missing. That is, very often the planned work is of a one-off nature so comparisons are not possible or the scopes are not the same. In such a case the collective doses for other types of work are looked at and a qualitative evaluation is made. In the case of steam generator replacement this is not the case. Over years of steam generator replacements world-wide a standard has been developed gradually. The first part of the following displays an overview of SGR and sets the Krsko SGR in perspective by applying dose analysis. The second part concentrates on the Krsko SGR itself and its ALARA aspects. (authors)

Steam generator replacement: a story of continuous improvement

International Nuclear Information System (INIS)

Sills, M.S.; Wilkerson, R.

2009-01-01

This paper provides a review of the history of steam generator replacement in the US focusing on the last five years. From the early replacements in the 1980s, there have been major technology improvements resulting in dramatically shorter outages and reduced radiological exposure for workers. Even though the changes for the last five years have been less dramatic, the improvement trend continues. No two steam generator replacement (SGR) projects are the same and there are some major differences including; the access path for the components to containment (is a construction opening in containment required), type of containment, number of steam generators, one piece or two piece replacement, plant type (Westinghouse, CE or B and W) and plant layout. These differences along with other variables such as delays due to plant operations and other activities not related to the steam generator replacement make analysis of performance data difficult. However, trends in outage performance and owner expectations can be identified. How far this trend will go is also discussed. Along with the trend of improved performance, there is also a significant variation in performance. Some of the contributors to this variation are identified. This paper addresses what is required for a successful outage, meeting the increasing expectations and setting new records. The authors will discuss various factors that contribute to the success of a steam generator replacement. These factors include technical issues and, equally important, organizational interface and the role the customer plays. Recommendations are provided for planning a successful steam generator replacement outage. (author)

Solid-State Thyratron Replacement. Final Report

Energy Technology Data Exchange (ETDEWEB)

Roth, Ian [Diversified Technologies, Inc., Bedford, MA

2017-12-12

Under this SBIR, DTI developed a solid-state switch as an alternative to legacy thyratron equipment. Our Phase II objective was to make a solid-state thyratron replacement that would provide equivalent or better performance, much higher reliability (at least a 20 year lifetime, compared to a thyratron’s two-year lifetime) and would sell for ~3x the cost of a thyratron, or less than $40k. We were successful in building a solid-state switch which could reliably function as a thyratron replacement. The unit was designed to directly replace the thyratrons currently being used at SLAC’s Linac Coherent Light Source (LCLS), and was built in a tank that was small enough to fit into the existing thyratron cabinet, providing a true form-fit-function replacement path. We tested the switch at the full operating specifications: 48 kV, 6.3 kA, and 1 µs risetime. We also demonstrated a peak-to-peak pulse jitter of 1.5 ns, which is five times shorter than is typical for thyratrons. This lower jitter would improve the performance of the LCLS beam. The predicted reliability is more than 80 years, which is 40 times greater than a thyratron.

48 CFR 908.7101-4 - Replacement of motor vehicles.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Replacement of motor....7101-4 Replacement of motor vehicles. (a) The replacement of motor vehicles shall be in accordance with... Heads of Contracting Activities may arrange to sell, as exchange sales, used motor vehicles being...

Slab replacement maturity guidelines.

Science.gov (United States)

2014-04-01

This study investigated the use of maturity method to determine early age strength of concrete in slab : replacement application. Specific objectives were (1) to evaluate effects of various factors on the compressive : maturity-strength relationship ...

REPLACEMENT IN RABBIT HERDS: A REVIEW

Directory of Open Access Journals (Sweden)

Ibrahim F.M. Marai

2010-08-01

Full Text Available Doe rabbit's replacement constitutes the annual renewal rate of new breeders that must be incorporated into the production stock. Criterion for culling non-productive animals differs significantly among fryer production colonies, foundation stocks and a colony with continuous enzootic disease or continuous malnourishment. In commercial rabbit production, good management improves the health and productivity of the entire herd, by reducing the all-time high replacement rates and improving economic viability. In the present article, a comprehensive review of numerous experiences in the rabbit production field of different countries, was presented. Basic recommendations for professional breeders were highlighted, covering critical issues such as the need for continuously upgrading the health status of the colony, the positive effect of   genetic selection and the nutritional conditioning and special treatment of young does being groomed as future replacements.

Strategies for replacement of obsolete equipment - including reverse engineering

International Nuclear Information System (INIS)

Irish, C.S.

2000-01-01

The presentation shall detail the challenges facing nuclear power plants with the replacement of obsolete equipment and the strategies used to overcome those challenges. The presentation will outline the common equipment types which are either obsolete or are becoming obsolete, with a focus on safety related components. The four options of the obsolete equipment replacement philosophy will be presented with replacement examples from each of the options shown for discussion purposes. Detailed examples from each of the four obsolete equipment replacement options of: commercially available equivalent component; modification of a commercial available component; reverse engineering of the original component; and finally, design changes using a new component, shall be presented to evaluate the advantages and disadvantages of each option. The presentation will include the technical challenges, cost and schedule concerns for each of the four options. Emphasis will be placed on the technological challenges associated with replacing old and obsolete equipment. The following is a bullet list of the challenges which will be discussed: Missing, misleading or no information on the original component; Acquiring information from the original equipment manufacturer and the plant; Using a sample component for the replacement evaluation and or reverse engineering; and Reverse engineering old equipment with newly available discrete components. The presentation will include the equivalency documentation using the EPRI guidelines when replacing an original component with a different yet form, fit and functional equivalent component. The presentation will conclude with a discussion of the advantages and disadvantages of the replacement of the obsolete component with a form, fit and functional equivalent component vs. the replacement of the original component with a new component with today's technology. (author)

Peptide nucleic acid probe for protein affinity purification based on biotin-streptavidin interaction and peptide nucleic acid strand hybridization.

Science.gov (United States)

Tse, Jenny; Wang, Yuanyuan; Zengeya, Thomas; Rozners, Eriks; Tan-Wilson, Anna

2015-02-01

We describe a new method for protein affinity purification that capitalizes on the high affinity of streptavidin for biotin but does not require dissociation of the biotin-streptavidin complex for protein retrieval. Conventional reagents place both the selectively reacting group (the "warhead") and the biotin on the same molecule. We place the warhead and the biotin on separate molecules, each linked to a short strand of peptide nucleic acid (PNA), synthetic polymers that use the same bases as DNA but attached to a backbone that is resistant to attack by proteases and nucleases. As in DNA, PNA strands with complementary base sequences hybridize. In conditions that favor PNA duplex formation, the warhead strand (carrying the tagged protein) and the biotin strand form a complex that is held onto immobilized streptavidin. As in DNA, the PNA duplex dissociates at moderately elevated temperature; therefore, retrieval of the tagged protein is accomplished by a brief exposure to heat. Using iodoacetate as the warhead, 8-base PNA strands, biotin, and streptavidin-coated magnetic beads, we demonstrate retrieval of the cysteine protease papain. We were also able to use our iodoacetyl-PNA:PNA-biotin probe for retrieval and identification of a thiol reductase and a glutathione transferase from soybean seedling cotyledons. Copyright © 2014 Elsevier Inc. All rights reserved.

Age replacement policy based on imperfect repair with random probability

International Nuclear Information System (INIS)

Lim, J.H.; Qu, Jian; Zuo, Ming J.

2016-01-01

In most of literatures of age replacement policy, failures before planned replacement age can be either minimally repaired or perfectly repaired based on the types of failures, cost for repairs and so on. In this paper, we propose age replacement policy based on imperfect repair with random probability. The proposed policy incorporates the case that such intermittent failure can be either minimally repaired or perfectly repaired with random probabilities. The mathematical formulas of the expected cost rate per unit time are derived for both the infinite-horizon case and the one-replacement-cycle case. For each case, we show that the optimal replacement age exists and is finite. - Highlights: • We propose a new age replacement policy with random probability of perfect repair. • We develop the expected cost per unit time. • We discuss the optimal age for replacement minimizing the expected cost rate.

A single - item replacement decision model for repairable spare ...

African Journals Online (AJOL)

In this paper, we present an analytical method for determining spare parts replacement over an infinite planning horizon. (The objective is to minimize the total system cost). We develop an exact and simple method for determining the time for equipment replacement or making decision about when to replace equipments, ...

Electropolishing of replacement steam generator channel heads at Millstone-2 PWR

International Nuclear Information System (INIS)

Hudson, M.J.B.; Raney, H.; Raney, D.; Spalaris, C.N.

1992-07-01

A field application of EPRI-developed steam generator electropolishing technique was performed at Millstone-2 PWR. The process was qualified under previous programs on a laboratory scale, but it was thought appropriate to scale up application to full size components. Replacement of steam generators at Millstone-2 provided a unique opportunity to demonstrate that electropolishing can be applied safely and at a cost which was judged to be recoverable after a small number of fuel cycles. The project, preparation, electropolishing and cleanup, was completed at the reactor site in 25 working days. An alternate, less costly electrolyte solution was qualified for use in future applications

Nonparametric adaptive age replacement with a one-cycle criterion

International Nuclear Information System (INIS)

Coolen-Schrijner, P.; Coolen, F.P.A.

2007-01-01

Age replacement of technical units has received much attention in the reliability literature over the last four decades. Mostly, the failure time distribution for the units is assumed to be known, and minimal costs per unit of time is used as optimality criterion, where renewal reward theory simplifies the mathematics involved but requires the assumption that the same process and replacement strategy continues over a very large ('infinite') period of time. Recently, there has been increasing attention to adaptive strategies for age replacement, taking into account the information from the process. Although renewal reward theory can still be used to provide an intuitively and mathematically attractive optimality criterion, it is more logical to use minimal costs per unit of time over a single cycle as optimality criterion for adaptive age replacement. In this paper, we first show that in the classical age replacement setting, with known failure time distribution with increasing hazard rate, the one-cycle criterion leads to earlier replacement than the renewal reward criterion. Thereafter, we present adaptive age replacement with a one-cycle criterion within the nonparametric predictive inferential framework. We study the performance of this approach via simulations, which are also used for comparisons with the use of the renewal reward criterion within the same statistical framework

16 CFR 501.3 - Replacement bags for vacuum cleaners.

Science.gov (United States)

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Replacement bags for vacuum cleaners. 501.3... REQUIREMENTS AND PROHIBITIONS UNDER PART 500 § 501.3 Replacement bags for vacuum cleaners. Replacement bags for..., provided: (a) The quantity of contents is expressed in terms of numerical count of the bags; (b) A...

Replacement Value of fermented millet ( Pennisetum americanum ...

African Journals Online (AJOL)

The replacement value of fermented millet for maize in the diets of Clarias gariepinus fingerlings reared in a recirculation system was determined. Five isonitrogenous diets were formulated to contain graded levels of fermented millet meal replacing 0, 20, 40, 60 and 80% of maize and fed to triplicate groups of fingerlings ...

41 CFR 51-6.14 - Replacement services.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Replacement services. 51-6.14 Section 51-6.14 Public Contracts and Property Management Other Provisions Relating to Public... § 51-6.14 Replacement services. If a service is on the Procurement List to meet the needs of a...

REPLACEMENT CONTROL OF INNOVATION MANAGERS: ORGANIZATIONAL AND ECONOMIC ASPECTS

Directory of Open Access Journals (Sweden)

E. V. Gurina

2011-01-01

Full Text Available The paper substantiates phases of specialists’ replacement ensuring innovation development of the national economy in Belarus, i.e. managers of innovation activity. Realization of replacement phases is presented within the system consisting of four blocks – objective, managing, controllable and providing. Analysis results of the current state of the innovation activity managers replacement system reveal main problems in interaction of its basic agents. The paper considers solution of specified problems in the context of formation of organizational and economic approaches to managing the innovation activity managers replacement system which presupposes modernization of organizational interrelations between state- run public authorities in the managing block and micro-incentive structures in the controllable block as well as the usage of the process approach in every phase of the replacement process. 

Reoperative aortic root replacement: Outcome in a contemporary series.

Science.gov (United States)

Esaki, Jiro; Leshnower, Bradley G; Binongo, Jose N; Lasanajak, Yi; McPherson, LaRonica; Thourani, Vinod H; Chen, Edward P

2017-09-01

Reoperative aortic root replacement is a challenging procedure associated with significant mortality and morbidity. The purpose of this study was to investigate the outcomes of reoperative aortic root replacement when performed in a number of complex clinical settings and to identify risk factors for operative mortality and long-term survival. From 2006 to 2015, 280 consecutive patients at an academic center underwent reoperative aortic root replacement after a variety of previous aortic or cardiac operations. Logistic regression and extended Cox proportional hazards regression analyses were used to determine risk factors for operative mortality and long-term survival, respectively. The mean age of patients was 52.5 ± 14.1 years. Prior operations included proximal aortic replacement in 113 patients, valve surgery in 162 patients, and coronary artery bypass grafting in 46 patients. Concomitant procedures included arch replacement in 135 patients, coronary artery bypass grafting in 68 patients, and mitral valve repair/replacement in 18 patients. Operative mortality was 14.3%. Five-year survival was 74.0%. Univariable analysis did not find previous root replacement, prior proximal aortic surgery, and concomitant arch replacement to be risk factors for operative mortality. In the multivariable analysis, chronic lung disease, prior myocardial infarction, and concomitant mitral valve surgery were risk factors for operative mortality. Age, peripheral artery disease, emergency, and concomitant mitral valve surgery were risk factors for mortality in the late phase. Reoperative aortic root replacement represents complex procedures carrying significant morbidity and mortality. Chronic lung disease, prior myocardial infarction, and concomitant mitral valve surgery were risk factors for operative mortality. Age, peripheral artery disease, emergency, and concomitant mitral valve surgery were risk factors for long-term mortality. Copyright © 2017 The American Association for

Strategies for replacement of obsolete equipment, including reverse engineering

International Nuclear Information System (INIS)

Irish, C.S.

2003-01-01

The presentation shall detail the challenges facing nuclear power plants with the replacement of obsolete equipment and the strategies used to overcome those challenges. The presentation will outline the common equipment types which are either obsolete or are becoming obsolete, with a focus on safety related components. The four options of the obsolete equipment replacement philosophy will be presented with replacement examples from each of the options shown for discussion purposes. Detailed examples from each of the four obsolete equipment replacement options of, (1) commercially available equivalent component, (2) modification of a commercial available component, (3) reverse engineering of the original component and finally (4) design changes using a new component, shall be presented to evaluate the advantages and disadvantages of each option. The presentation will include the technical challenges, cost and schedule concerns for each of the four options. Emphasis will be placed on the technological challenges associated with replacing old and obsolete equipment. The following is a bullet list of the challenges which will be discussed: 1) Missing, misleading or no information on the original component. 2) Acquiring information from the original equipment manufacturer and the plant. 3) Using a sample component for the replacement evaluation and or reverse engineering. 4) Reverse engineering old equipment with newly available discrete components. The presentation will include the equivalency documentation using the EPRI guidelines when replacing an original component with a different yet form, fit and functional equivalent component. The presentation will conclude with a discussion of the advantages and disadvantages of the replacement of the obsolete component with a form, fit and functional equivalent component vs. the replacement of the original component with a new component with today's technology. (author)

BWR control blade replacement strategies

Energy Technology Data Exchange (ETDEWEB)

Kennard, M W [Stoller Nuclear Fuel, NAC International, Pleasantville, NY (United States); Harbottle, J E [Stoller Nuclear Fuel, NAC International, Thornbury, Bristol (United Kingdom)

2000-02-01

The reactivity control elements in a BWR, the control blades, perform three significant functions: provide shutdown margin during normal and accident operating conditions; provide overall core reactivity control; and provide axial power shaping control. As such, the blades are exposed to the core's neutron flux, resulting in irradiation of blade structural and absorber materials. Since the absorber depletes with time (if B{sub 4}C is used, it also swells) and the structural components undergo various degradation mechanisms (e.g., embrittlement, corrosion), the blades have limits on their operational lifetimes. Consequently, BWR utilities have implemented strategies that aim to maximize blade lifetimes while balancing operational costs, such as extending a refuelling outage to shuffle high exposure blades. This paper examines the blade replacement strategies used by BWR utilities operating in US, Europe and Asia by assembling information related to: the utility's specific blade replacement strategy; the impact the newer blade designs and changes in core operating mode were having on those strategies; the mechanical and nuclear limits that determined those strategies; the methods employed to ensure that lifetime limits were not exceeded during operation; and blade designs used (current and replacement blades). (author)

BWR control blade replacement strategies

International Nuclear Information System (INIS)

Kennard, M.W.; Harbottle, J.E.

2000-01-01

The reactivity control elements in a BWR, the control blades, perform three significant functions: provide shutdown margin during normal and accident operating conditions; provide overall core reactivity control; and provide axial power shaping control. As such, the blades are exposed to the core's neutron flux, resulting in irradiation of blade structural and absorber materials. Since the absorber depletes with time (if B 4 C is used, it also swells) and the structural components undergo various degradation mechanisms (e.g., embrittlement, corrosion), the blades have limits on their operational lifetimes. Consequently, BWR utilities have implemented strategies that aim to maximize blade lifetimes while balancing operational costs, such as extending a refuelling outage to shuffle high exposure blades. This paper examines the blade replacement strategies used by BWR utilities operating in US, Europe and Asia by assembling information related to: the utility's specific blade replacement strategy; the impact the newer blade designs and changes in core operating mode were having on those strategies; the mechanical and nuclear limits that determined those strategies; the methods employed to ensure that lifetime limits were not exceeded during operation; and blade designs used (current and replacement blades). (author)

The caudal septum replacement graft.

Science.gov (United States)

Foda, Hossam M T

2008-01-01

To describe a technique for reconstructing the lost tip support in cases involving caudal septal and premaxillary deficiencies. The study included 120 patients with aesthetic and functional nasal problems resulting from the loss of caudal septal and premaxillary support. An external rhinoplasty approach was performed to reconstruct the lost support using a cartilaginous caudal septum replacement graft and premaxillary augmentation with Mersilene mesh. The majority of cases (75%) involved revisions in patients who had previously undergone 1 or more nasal surgical procedures. A caudal septum replacement graft was combined with premaxillary augmentation in 93 patients (77.5%). The mean follow-up period was 3 years (range, 1-12 years). The technique succeeded in correcting the external nasal deformities in all patients and resulted in a significant improvement in breathing in 74 patients (86%) with preoperative nasal obstruction. There were no cases of infection, displacement, or extrusion. The caudal septum replacement graft proved to be very effective in restoring the lost tip support in patients with caudal septal deficiency. Combining the graft with premaxillary augmentation using Mersilene mesh helped increase support and stability over long-term follow-up.

Results of Austin Moore replacement.

Directory of Open Access Journals (Sweden)

Jadhav A

1996-04-01

Full Text Available Forty cases of Austin Moore Replacement done for transcervical fractures of the femur in patients were reviewed after a period of 12 to 48 months postoperatively (mean 26 mth. 30 cases (75% had mild to severe pain of non-infective origin, starting as early as 6 months postoperatively. This was irrespective of the make, size or position (varus/valgus of the prosthesis. Though the Aufranc and Sweet clinical scoring was satisfactory in 65% cases, radiological evidence of complications like sinking, protrusion, etc. were seen in majority of the cases. Calcar resorption was seen in 34 cases (85% as early as 4 months postoperatively. Results of THR and bipolar replacement done for transcervical fractures in recent literature show 85% pain-free cases at 5 years. We feel that Austin Moore Replacement should be reserved for patients more than 65 years of age and those who are less active or debilitated because of other factors, because of increased acetabular wear with time in the younger individual. This is corroborated by unsatisfactory results in patients less than 65 years of age (p < 0.05.

EFFECTIVENESS OF A PROGRAMED TEXT IN TEACHING GYNECOLOGIC ONCOLOGY TO JUNIOR MEDICAL STUDENTS, A SOURCE BOOK ON THE DEVELOPMENT OF PROGRAMED MATERIALS FOR USE IN A CLINICAL DISCIPLINE.

Science.gov (United States)

WILDS, PRESTON L.; ZACHERT, VIRGINIA

THIS REPORT DESCRIBES A STUDY TO DETERMINE WHETHER PROGRAMED INSTRUCTION COULD BE USED TO IMPROVE THE TEACHING OF THE MANAGEMENT OF PATIENTS WITH GYNECOLOGIC NEOPLASMS TO JUNIOR MEDICAL STUDENTS. TWO PROGRAMED TEXTS WERE PREPARED--(1) A "CONTENT" TEXT, AN 830-FRAME LINEARLY PROGRAMED TEXT DESIGNED TO REPLACE CONVENTIONAL CLASSROOM…

Russia's atomic tsar: Viktor N. Mikhailov

International Nuclear Information System (INIS)

Reams, C.A.

1996-12-01

Minatom (Ministry of Atomic Energy) was created to manage Russia's nuclear weapons program in the age of disarmament. The ministry is responsible for the development, production, and maintenance of nuclear weapons, warhead dismantlement, the production of nuclear materials for weapons, the disposition of nuclear materials disassembled from warheads, the administration of Russia's vast nuclear weapons complex, the development of policy for the future role of Russia's nuclear complex and payment of employees entrusted with such tasks. Thus, Minatom is instrumental in the implementation of arms control, disarmament and nonproliferation agreements. The director of Minatom, Viktor N. Mikhailov, wields a great deal of power and influence over Russia's nuclear infrastructure. He is an important player amidst efforts to reduce the threats posed by Russia's decaying nuclear complex. There are certainly other personalities in the Russian government who influence Minatom; however, few affect the ministry as profoundly as Mikhailov. His ability to influence Russia's nuclear complex has been clearly demonstrated by his policies in relation to the US purchase of Russian highly enriched uranium, the planned fissile material storage facility at Mayak, materials protection, control and accountability programs, and his unwavering determination to sell Iran commercial nuclear technology. Mikhailov has also been a key negotiator when dealing with the US on issues of transparency of weapons dismantlement and fissile material disposition, as well as the use of US threat reduction funds. His policies and concerns in these areas will affect the prospects for the successful negotiation and implementation of future nuclear threat reduction programs and agreements with Russia

Russia`s atomic tsar: Viktor N. Mikhailov

Energy Technology Data Exchange (ETDEWEB)

Reams, C.A. [Los Alamos National Lab., NM (United States). Center for International Security Affairs

1996-12-01

Minatom (Ministry of Atomic Energy) was created to manage Russia`s nuclear weapons program in the age of disarmament. The ministry is responsible for the development, production, and maintenance of nuclear weapons, warhead dismantlement, the production of nuclear materials for weapons, the disposition of nuclear materials disassembled from warheads, the administration of Russia`s vast nuclear weapons complex, the development of policy for the future role of Russia`s nuclear complex and payment of employees entrusted with such tasks. Thus, Minatom is instrumental in the implementation of arms control, disarmament and nonproliferation agreements. The director of Minatom, Viktor N. Mikhailov, wields a great deal of power and influence over Russia`s nuclear infrastructure. He is an important player amidst efforts to reduce the threats posed by Russia`s decaying nuclear complex. There are certainly other personalities in the Russian government who influence Minatom; however, few affect the ministry as profoundly as Mikhailov. His ability to influence Russia`s nuclear complex has been clearly demonstrated by his policies in relation to the US purchase of Russian highly enriched uranium, the planned fissile material storage facility at Mayak, materials protection, control and accountability programs, and his unwavering determination to sell Iran commercial nuclear technology. Mikhailov has also been a key negotiator when dealing with the US on issues of transparency of weapons dismantlement and fissile material disposition, as well as the use of US threat reduction funds. His policies and concerns in these areas will affect the prospects for the successful negotiation and implementation of future nuclear threat reduction programs and agreements with Russia.

Replacement rod

International Nuclear Information System (INIS)

Hatfield, S.C.

1989-01-01

This patent describes in an elongated replacement rod for use with fuel assemblies of the type having two end fittings connected by guide tubes with a plurality of rod and guide tube cell defining spacer grids containing rod support features and mixing vanes. The grids secured to the guide tubes in register between the end fittings at spaced intervals. The fuel rod comprising: an asymmetrically beveled tip; a shank portion having a straight centerline; and a permanently diverging portion between the tip and the shank portion

Replacement of the JRR-3 computer system

Energy Technology Data Exchange (ETDEWEB)

Kato, Tomoaki; Kobayashi, Kenichi; Suwa, Masayuki; Mineshima, Hiromi; Sato, Mitsugu [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

2000-10-01

The JRR-3 computer system contributes to stable operation of JRR-3 since 1990. But now about 10 years have passed since it was designed and some problems have occurred. Under these situations, we should replace the old computer system for safe and stable operation. In this replacement, the system is improved as regards man-machine interface and efficiency about maintenance. The new system consists of three functions, which are 'the function of management for operation information' (renewal function), 'the function of management for facility information' (new function) and the function of management for information publication' (new function). By this replacement, New JRR-3 computer system can contribute to safe and stable operation. (author)

How to replace a reactor pressure vessel

International Nuclear Information System (INIS)

Huber, R.

1996-01-01

A potential life extending procedure for a nuclear reactor after, say, 40 years of service life, might in some circumstances be the replacement of the reactor pressure vessel. Neutron induced degradation of the vessel might make replacement by one of a different material composition desirable, for example. Although the replacement of heavy components, such as steam generators, has been possible for many years, the pressure vessel presents a much more demanding task if only because it is highly irradiated. Some preliminary feasibility studies by Siemens are reported for the two removal strategies that might be considered. These are removal of the entire pressure vessel in one piece and dismantling it into sections. (UK)

Replacement of the JRR-3 computer system

International Nuclear Information System (INIS)

Kato, Tomoaki; Kobayashi, Kenichi; Suwa, Masayuki; Mineshima, Hiromi; Sato, Mitsugu

2000-01-01

The JRR-3 computer system contributes to stable operation of JRR-3 since 1990. But now about 10 years have passed since it was designed and some problems have occurred. Under these situations, we should replace the old computer system for safe and stable operation. In this replacement, the system is improved as regards man-machine interface and efficiency about maintenance. The new system consists of three functions, which are 'the function of management for operation information' (renewal function), 'the function of management for facility information' (new function) and the function of management for information publication' (new function). By this replacement, New JRR-3 computer system can contribute to safe and stable operation. (author)

Mechanical Aortic Valve Replacement in Octogenarian

Directory of Open Access Journals (Sweden)

Irfan Tasoglu

2013-10-01

Full Text Available Aim: This study analyzes the long-term outcomes of mechanical aortic valve replacement in octogenarian patients. Material and Method: A retrospective review was performed on 23 octogenarian patients who underwent mechanical aortic valve replacement. Hospital mortality, postoperative intensive care unit stay, hospital stay and long-term results was examined. Estimates of the cumulative event mortality rate were calculated by the Kaplan-Meier method. Results: The mean age of all patients was 82.9±2.3 years and most were men (65.22%. The median ejection fraction was 45%. 73.91% of patients were in New York Heart Association class III-IV. Thirteen patients (56.52% in this study underwent combined procedure, the remaining 10 (43.48% patients underwent isolated aortic valve replacement. The most common valve size was 23 mm. The mean intensive care unit stay was 1.76±1.14 days. The mean hospital stay was 9.33±5.06 days. No complications were observed in 56.52% patients during their hospital stay. The overall hospital mortality was 8.7%. Follow-up was completed for all 23 patients. Median follow-up time was 33 months (1-108 months. Actuarial survival among discharged from hospital was 59% at 5 years. Discussion: Mechanical aortic valve replacement is a safe procedure in octogenarian patients and can be performed safely even in combined procedure.

Steam generator replacement at Doel 3 NPP (Belgium)

International Nuclear Information System (INIS)

Danhier, B.

1993-01-01

The reasons are presented that led to the conclusion that the most cost-effective strategy for the Doel 3 unit was the immediate replacement of the SG. Discussed are the advantages and drawbacks of the replacement techniques, the so-called 2, 3 and 4 cuts methods. The advantages are emphasized of intensive use of computer aided engineering in this kind of backfitting. The methodology applied to combine a power uprating of 10% over the nominal power with the steam generator replacement is presented. (author) 1 fig

Canadian Organ Replacement Register (CORR: Reflecting the Past and Embracing the Future

Directory of Open Access Journals (Sweden)

Louise M Moist

2014-10-01

Full Text Available Introduction: The Canadian Organ Replacement Register (CORR is the only Canadian information system on kidney and extra-kidney organ failure and transplantation in Canada. CORR's mandate is to record and analyze the level of activity and outcomes of vital organ transplantation and treatment of end stage kidney disease using dialysis, either hemodialysis or peritoneal dialysis, activities across Canada. The Canadian Organ Replacement Register was officially launched in 1987, and it included transplantation of extra-renal vital organs (liver, heart, lung, pancreas, bowel, in addition to renal transplantation and replacement therapy, with new financial support from the provinces. Objective: This manuscript describes the process of data acquisition and reporting, focusing on the patients with end stage kidney disease on dialysis, with data reported from the 2014 CORR Annual Data Report and the Center-Specific Reports on Clinical Measures. Methods: CORR is currently housed in the Canadian Institute for Health Information and collects data from hospital dialysis programs, regional transplant programs, organ procurement organizations and kidney dialysis services offered at independent health facilities. Data on patients is collected by completion of survey forms for each patient at the start of dialysis or receiving a transplant, using the Initial Registration form, and yearly follow up forms, which collects data on the status of the patient as of October 31 st . Results: The incident rate per million population (RPMP has remained stable with the exception of the 65+ age group with has experience a modest decrease since 2001. However, there has been an increasing prevalence of ESKD diagnoses, with the highest rate per million population (RPMP amongst the age group 65+ years. This is likely attributed to gradual improving patient survival. Between 2003 and 2012, nearly 90% of dialysis patients younger than < 18 and 26% of patients 75+ years survived for

[Update in continuous renal replacement techniques].

Science.gov (United States)

Romero-García, M; de la Cueva-Ariza, L; Delgado-Hito, P

2013-01-01

Acute renal failure affects 25% of patients hospitalized in intensive care units. Despite technological advances, the mortality of these patients is still high due to its associated complications. Continuous renal replacement techniques are one of the treatments for acute renal failure because they make it possible to treat the complications and decrease mortality. The nurse's knowledge and skills regarding these techniques will be decisive for the success of the therapy. Consequently, the nurse's experience and training are key components. The objective of this article is to update the knowledge on continuous renal replacement techniques. Keeping this in mind, a review has been made of the physical and chemical principles such as diffusion and convection, among others. A description of the different continuous renal replacement techniques, a presentation of the main vascular access, and a description of the nursing cares and complications related to techniques used have also been provided. Copyright © 2012 Elsevier España, S.L. y SEEIUC. All rights reserved.

Scope Complexity Options Risks Excursions (SCORE) Factor Mathematical Description.

Energy Technology Data Exchange (ETDEWEB)

Gearhart, Jared Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Samberson, Jonell Nicole [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Shettigar, Subhasini [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jungels, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Welch, Kimberly M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Dean A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2017-03-01

The purpose of the Scope, Complexity, Options, Risks, Excursions (SCORE) model is to estimate the relative complexity of design variants of future warhead options, resulting in scores. SCORE factors extend this capability by providing estimates of complexity relative to a base system (i.e., all design options are normalized to one weapon system). First, a clearly defined set of scope elements for a warhead option is established. The complexity of each scope element is estimated by Subject Matter Experts (SMEs), including a level of uncertainty, relative to a specific reference system. When determining factors, complexity estimates for a scope element can be directly tied to the base system or chained together via comparable scope elements in a string of reference systems that ends with the base system. The SCORE analysis process is a growing multi-organizational Nuclear Security Enterprise (NSE) effort, under the management of the NA-12 led Enterprise Modeling and Analysis Consortium (EMAC). Historically, it has provided the data elicitation, integration, and computation needed to support the out-year Life Extension Program (LEP) cost estimates included in the Stockpile Stewardship Management Plan (SSMP).

Replacement of input/output cables of the digital control computers at Gentilly 2

International Nuclear Information System (INIS)

Melancon, P.; Lafreniere, P.

1991-01-01

During the 1990 annual outage at Gentilly 2 the Preventive Maintenance Program inspections on the digital control computers (DCCs) revealed an alarming degradation of cable insulation at several locations. It was found that approximately 20% of the cable connector assemblies inspected showed signs of degradation. These findings raised the concern of an increased risk of random short-circuit faults at the very heart of the station control system. Given the excellent reliability of the Gentilly 2 DCCs and their inherent design robustness, it was decided to proceed with the replacement of all of the complete cable connector assemblies within a reasonable time frame. It is planned to replace all assemblies of DCCX and DCCY during the 1991 annual outage. The degradation of the insulation was traced to a material incompatibility problem originating during cable manufacture. A migration of the plastifier contained in the PVC of the transparent sheaths, surrounding many of the cable conductors to terminal block connections, resulted in the chemical attack of the conductor insulation. This paper summarizes the problem identification and disposition process followed by Gentilly 2 Technical Unit personnel

Replacement of Co-base alloy for radiation exposure reduction in the primary system of PWR

International Nuclear Information System (INIS)

Han, Jeong Ho; Nyo, Kye Ho; Lee, Deok Hyun; Lim, Deok Jae; Ahn, Jin Keun; Kim, Sun Jin

1996-01-01

Of numerous Co-free alloys developed to replace Co-base stellite used in valve hardfacing material, two iron-base alloys of Armacor M and Tristelle 5183 and one nickel-base alloy of Nucalloy 488 were selected as candidate Co-free alloys, and Stellite 6 was also selected as a standard hardfacing material. These four alloys were welded on 316SS substrate using TIG welding method. The first corrosion test loop of KAERI simulating the water chemistry and operation condition of the primary system of PWR was designed and fabricated. Corrosion behaviors of the above four kinds of alloys were evaluated using this test loop under the condition of 300 deg C, 1500 psi. Microstructures of weldment of these alloys were observed to identify both matrix and secondary phase in each weldment. Hardnesses of weld deposit layer including HAZ and substrate were measured using micro-Vickers hardness tester. The status on the technology of Co-base alloy replacement in valve components was reviewed with respect to the classification of valves to be replaced, the development of Co-free alloys, the application of Co-free alloys and its experiences in foreign NPPs, and the Co reduction program in domestic NPPs and industries. 18 tabs., 20 figs., 22 refs. (Author)

Replacement of Mushroom Cage Gastrostomy Tube Using a Modified Technique to Allow Percutaneous Replacement with an Endoscopic Tube in Patients with Amyotrophic Lateral Sclerosis

International Nuclear Information System (INIS)

Ammar, Thoraya; Rio, Alan; Ampong, Mary Ann; Sidhu, Paul S.

2010-01-01

Radiologic inserted gastrostomy (RIG) is the preferred method in our institution for enteral feeding in amyotrophic lateral sclerosis (ALS). Skin-level primary-placed mushroom cage gastrostomy tubes become tight with weight gain. We describe a minimally invasive radiologic technique for replacing mushroom gastrostomy tubes with endoscopic mushroom cage tubes in ALS. All patients with ALS who underwent replacement of a RIG tube were included. Patients were selected for a modified replacement when the tube length of the primary placed RIG tube was insufficient to allow like-for-like replacement. Replacement was performed under local anesthetic and fluoroscopic guidance according to a preset technique, with modification of an endoscopic mushroom cage gastrostomy tube to allow percutaneous placement. Assessment of the success, safety, and durability of the modified technique was undertaken. Over a 60-month period, 104 primary placement mushroom cage tubes in ALS were performed. A total of 20 (19.2%) of 104 patients had a replacement tube positioned, 10 (9.6%) of 104 with the modified technique (male n = 4, female n = 6, mean age 65.5 years, range 48-85 years). All tubes were successfully replaced using this modified technique, with two minor complications (superficial wound infection and minor hemorrhage). The mean length of time of tube durability was 158.5 days (range 6-471 days), with all but one patient dying with a functional tube in place. We have devised a modification to allow percutaneous replacement of mushroom cage gastrostomy feeding tubes with minimal compromise to ALS patients. This technique allows tube replacement under local anesthetic, without the need for sedation, an important consideration in ALS.

Dead pixel replacement in LWIR microgrid polarimeters.

Science.gov (United States)

Ratliff, Bradley M; Tyo, J Scott; Boger, James K; Black, Wiley T; Bowers, David L; Fetrow, Matthew P

2007-06-11

LWIR imaging arrays are often affected by nonresponsive pixels, or "dead pixels." These dead pixels can severely degrade the quality of imagery and often have to be replaced before subsequent image processing and display of the imagery data. For LWIR arrays that are integrated with arrays of micropolarizers, the problem of dead pixels is amplified. Conventional dead pixel replacement (DPR) strategies cannot be employed since neighboring pixels are of different polarizations. In this paper we present two DPR schemes. The first is a modified nearest-neighbor replacement method. The second is a method based on redundancy in the polarization measurements.We find that the redundancy-based DPR scheme provides an order-of-magnitude better performance for typical LWIR polarimetric data.

Three Steam Generator Replacement Projects in 1995

International Nuclear Information System (INIS)

Holz, R.; Clavier, G.

1996-01-01

Since the companies Siemens AG and Framatome S. A. joined their experience and efforts in the field of steam generator replacements and formed a consortium in 1991, the following projects were performed in 1995: Ringhals 3, Tihange 3 and Asco 1. Further projects will follow in 1996, i. e., Doel 4 and Asco 2. Currently, this European consortium is bidding for the contract to replace the steam generators at the Krsko NPP and hopes to be awarded in 1996. An overview of the way the Consortium Siemens and Framatome approaches SG replacement projects is given based on the projects performed in 1995. Various aspects of project planning, management, licensing, personnel qualification and techniques used on site will be discussed. (author)

Testosterone Replacement, Muscle Strength, and Physical Function

Directory of Open Access Journals (Sweden)

You-Seon Nam

2018-05-01

Full Text Available Muscle strength and physical function decrease in older men, as do testosterone levels. Nonetheless, the effects of testosterone replacement therapy on muscle strength and physical function remain inconclusive and equivocal. We conducted a rapid systematic review, the results of which showed that testosterone replacement does not affect muscle strength (measured by hand grip strength and leg muscle strength, although it may increase physical function (measured by the 6-minute walk test, Physical Activity Scale for the Elderly score, and other physical performance tests. However, most of the studies were conducted in the United States or Europe and did not include participants from Asian or other ethnic backgrounds; therefore, further studies are needed to evaluate the effects of testosterone replacement in a broader population.

Criteria for the replacement of restorations

DEFF Research Database (Denmark)

Wilson, Nairn; Lynch, Christopher; Brunton, Paul Brunton

2016-01-01

The replacement of a restoration is one of the most common procedures in dentistry. However, the criteria for such intervention, excluding catastrophic failure and persistent discomfort and pain, continue to be the subject of considerable debate. The decision-making process remains subjective...... on the part of the treating clinician, while the evidence base for refurbishment and repair rather than replacement for the management of defective and failing restorations continues to grow and strengthen. This article, prepared as an Academy of Operative Dentistry European Section consensus publication...

Differences in the stress distribution in the distal femur between patellofemoral joint replacement and total knee replacement: a finite element study

NARCIS (Netherlands)

van Jonbergen, H.P.; Innocenti, B.; Gervasi, G.L.; Labey, L.; Verdonschot, N.J.

2012-01-01

BACKGROUND: Patellofemoral joint replacement is a successful treatment option for isolated patellofemoral osteoarthritis. However, results of later conversion to total knee replacement may be compromised by periprosthetic bone loss. Previous clinical studies have demonstrated a decrease in distal

Optimal household refrigerator replacement policy for life cycle energy, greenhouse gas emissions, and cost

International Nuclear Information System (INIS)

Kim, Hyung Chul; Keoleian, Gregory A.; Horie, Yuhta A.

2006-01-01

Although the last decade witnessed dramatic progress in refrigerator efficiencies, inefficient, outdated refrigerators are still in operation, sometimes consuming more than twice as much electricity per year compared with modern, efficient models. Replacing old refrigerators before their designed lifetime could be a useful policy to conserve electric energy and greenhouse gas emissions. However, from a life cycle perspective, product replacement decisions also induce additional economic and environmental burdens associated with disposal of old models and production of new models. This paper discusses optimal lifetimes of mid-sized refrigerator models in the US, using a life cycle optimization model based on dynamic programming. Model runs were conducted to find optimal lifetimes that minimize energy, global warming potential (GWP), and cost objectives over a time horizon between 1985 and 2020. The baseline results show that depending on model years, optimal lifetimes range 2-7 years for the energy objective, and 2-11 years for the GWP objective. On the other hand, an 18-year of lifetime minimizes the economic cost incurred during the time horizon. Model runs with a time horizon between 2004 and 2020 show that current owners should replace refrigerators that consume more than 1000 kWh/year of electricity (typical mid-sized 1994 models and older) as an efficient strategy from both cost and energy perspectives

A model for the design and programming of multi-cores

NARCIS (Netherlands)

Jesshope, C.; Grandinetti, L.

2008-01-01

This paper describes a machine/programming model for the era of multi-core chips. It is derived from the sequential model but replaces sequential composition with concurrent composition at all levels in the program except at the level where the compiler is able to make deterministic decisions on

1998 researchers' conference proceedings, Amarillo College Business and Industry Center

International Nuclear Information System (INIS)

1998-01-01

The first Strategic Arms Reduction Treaties (START 1 and 2) signed by the US and the Soviet Union call for a reduction in strategic nuclear warheads to about one-third of 1990 levels and a complete elimination of land-based, multiple-warhead missiles. As a consequence of dismantling nuclear warheads, a significant portion of the inventory of nuclear materials that were formerly parts of deployed weapon systems was designated to be handled and/or stored at the Pantex Plant near Amarillo, Texas. To facilitate research integration between the national laboratories and the universities, the Center has divided its technical activities into seven focus areas. For Nuclear and Other Materials Studies, the focus areas are Materials Science, Plutonium Processing and handling, Nuclear Materials Storage, and analytical Development. The Environment, Safety and Health focus areas are Environmental Restoration and Protection, Safety and Health, and Waste Management. Research projects within each area are presented

Safety benefits from CANDU reactor replacement - a case study

International Nuclear Information System (INIS)

Mottram, R.; Millard, J.W.F.; Purdy, P.

2011-01-01

Both total core replacement and core retubing have been used in the CANDU industry. For future plant refurbishments, based on experience both in new construction and in recent refurbishments, the concept of total core replacement has been revisited. This builds on practices for replacement of other large plant equipment like boilers. The Bruce CANDU reactors, with their local shield tanks built around the Calandria and containment closely located around that Calandria Shield Tank Assembly (CSTA), are believed to be good candidates for core replacement. A structured process was used to design a replacement CSTA suitable for Bruce A use. The work started with a study of opportunities for safety enhancements in the core. This progressed into design studies and related design assist safety analysis on the reactor. A key element of the work involved consideration of how verified features from later CANDU designs, and from our new reactor design work, could be tailored to fit this replacement core. The replacement reactor core brings in structural improvements in both calandria and end shield, and safety improvements like the natural circulation enhancing moderator cooling layout and further optimized reactivity layouts to improve shutdown system performance. Bruce Power are currently studying the business implications of this and retube techniques as part of preparation for future refurbishments. The work explained in this paper is in the context of the safety related changes and the work to choose and quantify them. (author)

Safety benefits from CANDU reactor replacement. A case study

International Nuclear Information System (INIS)

Mottram, R.; Millard, J.W.F.; Purdy, P.

2011-01-01

Both total core replacement and core retubing have been used in the CANDU industry. For future plant refurbishments, based on experience both in new construction and in recent refurbishments, the concept of total core replacement has been revisited. This builds on practices for replacement of other large plant equipment like boilers. The Bruce CANDU reactors, with their local shield tanks built around the Calandria and containment closely located around that Calandria Shield Tank Assembly (CSTA), are believed to be good candidates for core replacement. A structured process was used to design a replacement CSTA suitable for Bruce A use. The work started with a study of opportunities for safety enhancements in the core. This progressed into design studies and related design assist safety analysis on the reactor. A key element of the work involved consideration of how verified features from later CANDU designs, and from our new reactor design work, could be tailored to fit this replacement core. The replacement reactor core brings in structural improvements in both calandria and end shield, and safety improvements like the natural circulation enhancing moderator cooling layout and further optimized reactivity layouts to improve shutdown system performance. Bruce Power are currently studying the business implications of this and retube techniques as part of preparation for future refurbishments. The work explained in this paper is in the context of the safety related changes and the work to choose and quantify them. (author)

Heart valve replacement with the Sorin tilting-disc prosthesis. A 10-year experience.

Science.gov (United States)

Milano, A; Bortolotti, U; Mazzucco, A; Mossuto, E; Testolin, L; Thiene, G; Gallucci, V

1992-02-01

From 1978 to 1988, 697 patients with a mean age of 48 +/- 11 years (range 5 to 75 years) received a Sorin tilting-disc prosthesis; 358 had had aortic valve replacement, 247 mitral valve replacement, and 92 mitral and aortic valve replacement. Operative mortality rates were 7.8%, 11.3%, and 10.8%, respectively, in the three groups. Cumulative duration of follow-up is 1650 patient-years for aortic valve replacement (maximum follow-up 11.4 years), 963 patient-years for mitral valve replacement (maximum follow-up 9.9 years) and 328 patient-years for mitral and aortic valve replacement (maximum follow-up 9.4 years). Actuarial survival at 9 years is 72% +/- 4% after mitral valve replacement, 70% +/- 3% after aortic valve replacement, and 50% +/- 12% after mitral and aortic valve replacement, and actuarial freedom from valve-related deaths is 97% +/- 2% after mitral valve replacement, 92% +/- 2% after aortic valve replacement, and 62% +/- 15% after mitral and aortic valve replacement. Thromboembolic events occurred in 21 patients with aortic valve replacement (1.3% +/- 0.2%/pt-yr), in 12 with mitral valve replacement (1.2% +/- 0.3% pt-yr), and in seven with mitral and aortic valve replacement (2.1% +/- 0.8%), with one case of prosthetic thrombosis in each group; actuarial freedom from thromboembolism at 9 years is 92% +/- 3% after mitral valve replacement, 91% +/- 3% after aortic valve replacement, and 74% +/- 16% after mitral and aortic valve replacement. Anticoagulant-related hemorrhage was observed in 15 patients after aortic valve replacement (0.9% +/- 0.2%/pt-yr), in 9 after mitral valve replacement (0.9% +/- 0.3%/pt-yr), and in 6 with mitral and aortic valve replacement (0.9% +/- 0.5%/pt-yr); actuarial freedom from this complication at 9 years is 94% +/- 2% after aortic valve replacement, 91% +/- 4% after mitral valve replacement, and 68% +/- 16% after mitral and aortic valve replacement. Actuarial freedom from reoperation at 9 years is 97% +/- 2% after mitral and

49 CFR 224.109 - Inspection, repair, and replacement.

Science.gov (United States)

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Inspection, repair, and replacement. 224.109 Section 224.109 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD..., Inspection, and Maintenance of Retroreflective Material § 224.109 Inspection, repair, and replacement. (a...

Decommissioning and equipment replacement of nuclear power plants under uncertainty

International Nuclear Information System (INIS)

Takashima, Ryuta; Naito, Yuta; Kimura, Hiroshi; Madarame, Haruki

2007-01-01

This study examines the optimal timing for the decommissioning and equipment replacement of nuclear power plants. We consider that the firm has two options of decommissioning and equipment replacement, and determines to exercise these options under electricity price uncertainty. This problem is formulated as two optimal stopping problems. The solution of this model provides the value of the nuclear power plant and the threshold values for decommissioning and replacement. The dependence of decommissioning and replacement strategies on uncertainty and each cost is shown. In order to investigate the probability of events for decommissioning and replacement, Monte Carlo calculations are performed. We also show the probability distribution and the conditional expected time for each event. (author)

Paired replacement fuel assemblies for BWR-type reactor

International Nuclear Information System (INIS)

Oguchi, Kazushige.

1997-01-01

There are disposed a large-diameter water rod constituting a non-boiling region at a central portion and paired replacement fuel assemblies for two streams having the same average enrichment degree and different amount of burnable poisons. The paired replacement fuel assemblies comprise a first fuel assembly having a less amount of burnable poisons and a second fuel assembly having a larger amount of burnable poisons. A number of burnable poison-containing fuel rods in adjacent with the large diameter water rod is increased in the second fuel assembly than the first fuel assembly. Then, the poison of the paired replacement fuel assemblies for the BWR type reactor can be annihilated simultaneously at the final stage of the cycle. Accordingly, fuels for a BWR type reactor excellent in economical property and safety and facilitating the design of the replacement reactor core can be obtained. (N.H.)

23 CFR 661.19 - When is a bridge eligible for replacement?

Science.gov (United States)

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false When is a bridge eligible for replacement? 661.19... replacement? To be eligible for replacement, the bridge must be considered structurally deficient or functionally obsolete and must be in accordance with 23 CFR part 650.409(a) for bridge replacement. After an...

Semantic Factors Predict the Rate of Lexical Replacement of Content Words

OpenAIRE

Vejdemo, Susanne; H?rberg, Thomas

2016-01-01

The rate of lexical replacement estimates the diachronic stability of word forms on the basis of how frequently a proto-language word is replaced or retained in its daughter languages. Lexical replacement rate has been shown to be highly related to word class and word frequency. In this paper, we argue that content words and function words behave differently with respect to lexical replacement rate, and we show that semantic factors predict the lexical replacement rate of content words. For t...

Method and refrigerants for replacing existing refrigerants in centrifugal compressors

International Nuclear Information System (INIS)

Kopko, W.L.

1991-01-01

This patent describes a method for replacing an existing refrigerant in a centrifugal compressor. It comprises selecting a desired impeller Mach number for the centrifugal compressor; selecting a base refrigerant constituent; combining at least one additive refrigerant constituent with the base refrigerant constituent to form a replacement refrigerant having at least one physical or chemical property different from the existing refrigerant and substantially providing the desired impeller Mach number in the centrifugal compressor; and replacing the existing refrigerant with the replacement refrigerant

Utilization of fermented animal by-product blend as fishmeal replacer in the diet of Labeo rohita

Directory of Open Access Journals (Sweden)

Ayan Samaddar

2015-05-01

Full Text Available Experiments were carried out to evaluate efficiency of Labeo rohita to utilize fermented animal protein blend containing slaughter house blood (SHB and fish offal (FO as dietary fishmeal (FM replacer. Five isoproteic (30%, isolipidic (8% and isoenergitic (15.00 kJ g−1 feed were prepared by replacing 0 (T1, 25 (T2, 50 (T3, 75 (T4 and 100% (T5 FM protein with the fermented blend and fingerlings of L. rohita (mean weight 2.07 g were fed each of these feed in triplicate groups. The results showed that apparent digestibility coefficient (ADC of protein significantly increased in T3–T5, while ADC of lipid and total amino acid absorption rate increased in T2–T5 as compared to control (T1. Among the essential amino acids (EAA, arginine exhibited maximum absorption followed by histidine, phenylalanine, valine and lysine while aspartic acid showed a high absorption among the non-essential amino acids (NAA. Fish fed up to 75% of replacement level (T4 did not show any significant difference (P < 0.05 in weight gain (WG, specific growth rate (SGR, feed conversion ratio (FCR, protein efficiency ratio (PER and apparent net protein utilization (ANPU between the dietary groups (T1–T4. But FCR was increased and other growth parameters were significantly reduced in 100% replacement group (T5, while body muscle protein was significantly reduced in both T4 and T5. Deposition of EAA (except histidine and methionine in T4 and NAA (except cystine in both T4 and T5 in the muscle of fish were also significantly reduced as compared to control (T1. Multi-objective optimization programming technique was used to determine FM replacement level that optimized all the growth parameters (WG, SGR, FCR and PER simultaneously. By using Global Criterion method, it was obtained that 21.11% replacement of FM by the fermented blend was ideal for optimum growth of L. rohita.

A daily herd Markov-chain model to study the reproductive and economic impact of reproductive programs combining timed artificial insemination and estrus detection.

Science.gov (United States)

Giordano, J O; Kalantari, A S; Fricke, P M; Wiltbank, M C; Cabrera, V E

2012-09-01

Our objective was to compare the economic and reproductive performance of programs combining timed artificial insemination (TAI) and different levels of AI after estrus detection (ED) using a daily Markov-chain model. A dairy herd was modeled with every cow following daily probabilistic events of aging, replacement, mortality, pregnancy, pregnancy loss, and calving. The probability of pregnancy depended on the combination of probability of insemination and conception rate (CR). All nonpregnant cows had a probability of pregnancy between the end of the voluntary waiting period and days in milk cutoff for AI. After the cutoff, cows were labeled as do not breed and replaced when milk production was below a minimum milk threshold. A similar model was created to represent a replacement heifer herd to simulate and adjust the supply and demand of replacements. The net value (NV) of a program was the sum of milk income over feed cost, replacement and mortality cost, income from newborns, and reproductive costs. The model was used to compare the NV of 19 programs. One program used 100% TAI (42% CR for first TAI and 30% for second-and-later services), whereas the other programs combined TAI with ED. The proportion of cows receiving AI after ED for the combined programs ranged from 30 to 80%, with levels of CR of 25, 30, and 35%. As the proportion of cows receiving AI after ED increased, the CR of cows receiving TAI decreased. The combined programs with CR of 35% for cows receiving AI after ED had the greatest NV and reproductive performance at all levels of ED. The program using 100% TAI had greater NV and better reproductive performance than all programs with 25% CR after ED inseminations, whereas it had very similar performance to combined programs with up to 60% of cows receiving AI after ED and 30% CR. The factor with the greatest relative contribution to the differences among programs was income over feed cost, followed by replacement and reproductive costs. Adjusting

Clinical study on postoperative steroid hormon replacement for preclinical Cushing's syndrome

International Nuclear Information System (INIS)

Furuta, Nozomu; Koide, Haruhisa; Sasaki, Hiroshi; Miki, Jun; Kimura, Takahiro; Egawa, Shin

2009-01-01

Diagnostic criteria for preclinical Cushing's syndrome (PCS) were reported in 1996. However, requirement of postoperative steroid hormone replacement is still controversial issue. In this study, we observed recent surgical cases retrospectively and evaluate the use of postoperative steroid hormone replacement. Eighteen patients with PCS underwent surgery from 1997 to 2007 in Jikei University Hospital. Thirteen of them received postoperative steroid hormone replacement. We investigated preoperative hormone activity by 131 I-adosterol scintigraphy and suppression of adrenocorticotropic hormone (ACTH) and evaluated the requirement of postoperative steroid hormone replacement. Preoperative serum cortisol was normal range in all patients. Serum ACTH was suppressed in 10 of them (56%). In 131 I-adosterol scintigraphy, accumulation in ipsilateral side was observed in all patients. Accumulation in contralateral side was observed in 13 patients whose serum ACTH had tendency to be suppressed. Mean period of steroid hormone replacement was 19.8 weeks. Patients with lower preoperative ACTH tended to require longer period until withdrawal of steroid hormone replacement. In addition, patients received steroid hormone replacement with higher starting dose significantly required longer period. Three of them had complications during tapering of steroid hormone. Postoperative adrenal insufficiency is important issue as postoperative management of PCS patients whose function of contralateral adrenal or pituitary gland is suppressed. 131 I-adosterol scintigraphy and preoperative serum ACTH were important factors to evaluate the requirement of postoperative steroid hormone replacement. Especially, patients with low preoperative serum ACTH tended to require long duration of postoperative steroid hormone replacement. On the other hand, patients with accumulation of contralateral side in 131 I-adosterol scintigraphy and without suppression of serum ACTH may not require steroid hormone

30 CFR 57.4203 - Extinguisher recharging or replacement.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Extinguisher recharging or replacement. 57.4203 Section 57.4203 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND... Prevention and Control Firefighting Equipment § 57.4203 Extinguisher recharging or replacement. Fire...

30 CFR 56.4203 - Extinguisher recharging or replacement.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Extinguisher recharging or replacement. 56.4203 Section 56.4203 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND... Prevention and Control Firefighting Equipment § 56.4203 Extinguisher recharging or replacement. Fire...

Opportunity-based block replacement: the single component case

NARCIS (Netherlands)

R. Dekker (Rommert); E. Smeitink

1991-01-01

textabstractIn this paper we consider a block replacement model in which a component can be replaced preventively at maintenance opportunities only. Maintenance opportunities occur randomly and are modelled through a renewal process. In the first, theoretical part of the paper we derive an

Thyroid hormone replacement therapy

NARCIS (Netherlands)

Wiersinga, W. M.

2001-01-01

Thyroid hormone replacement has been used for more than 100 years in the treatment of hypothyroidism, and there is no doubt about its overall efficacy. Desiccated thyroid contains both thyroxine (T(4)) and triiodothyronine (T(3)); serum T(3) frequently rises to supranormal values in the absorption

Vascular complications associated with transcatheter aortic valve replacement.

Science.gov (United States)

Sardar, M Rizwan; Goldsweig, Andrew M; Abbott, J Dawn; Sharaf, Barry L; Gordon, Paul C; Ehsan, Afshin; Aronow, Herbert D

2017-06-01

Transcatheter aortic valve replacement (TAVR) is now an accepted pathway for aortic valve replacement for patients who are at prohibitive, severe and intermediate risk for traditional aortic valve surgery. However, with this rising uptrend and adaptation of this new technology, vascular complications and their management remain an Achilles heel for percutaneous aortic valve replacement. The vascular complications are an independent predictor of mortality for patients undergoing TAVR. Early recognition of these complications and appropriate management is paramount. In this article, we review the most commonly encountered vascular complications associated with currently approved TAVR devices and their optimal percutaneous management techniques.

Replacement energy, capacity, and reliability costs for permanent nuclear reactor shutdowns

International Nuclear Information System (INIS)

VanKuiken, J.C., Buehring, W.A.; Hamilton, S.; Kavicky, J.A.; Cavallo, J.D.; Veselka, T.D.; Willing, D.L.

1993-10-01

Average replacement power costs are estimated for potential permanent shutdowns of nuclear electricity-generating units. Replacement power costs are considered to include replacement energy, capacity, and reliability cost components. These estimates were developed to assist the US Nuclear Regulatory Commission in evaluating regulatory issues that potentially affect changes in serious reactor accident frequencies. Cost estimates were derived from long-term production-cost and capacity expansion simulations of pooled utility-system operations. Factors that affect replacement power cost, such as load growth, replacement sources of generation, and capital costs for replacement capacity, were treated in the analysis. Costs are presented for a representative reactor and for selected subcategories of reactors, based on estimates for 112 individual reactors

Severe Heterotopic Ossification following Total Knee Replacement

Directory of Open Access Journals (Sweden)

Alexander L. Dodds

2014-01-01

Full Text Available Although the incidence of minor heterotopic ossification is probably higher than what is usually expected, severe heterotopic ossification (HO is an extremely rare event following total knee replacement surgery. We present the case of a 66-year-old woman who initially had achieved an excellent range of motion following bilateral uncemented rotating platform total knee replacement, before presenting with pain and loss of range of motion at 2 months after surgery. Severe HO was diagnosed on X-rays. Treatment consisted of nonoperative measures only, including physiotherapy with hydrotherapy and anti-inflammatories. She eventually regained her range of motion when seen at 8 months after operation. This case illustrates that nonoperative treatment without the use of radiotherapy or surgery can be used to safely resolve stiffness caused by HO after total knee replacement.

A Hybrid Integrated Laboratory and Inquiry-Based Research Experience: Replacing Traditional Laboratory Instruction with a Sustainable Student-Led Research Project

Science.gov (United States)

Hartings, Matthew R.; Fox, Douglas M.; Miller, Abigail E.; Muratore, Kathryn E.

2015-01-01

The Department of Chemistry at American University has replaced its junior- and senior-level laboratory curriculum with two, two-semester long, student-led research projects as part of the department's American Chemical Society-accredited program. In the first semester of each sequence, a faculty instructor leads the students through a set of…

Report on a Zero-Knowledge Protocal Tabletop Exercise.

Energy Technology Data Exchange (ETDEWEB)

Marleau, Peter [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Brubaker, Erik [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Deland, Sharon M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hilton, Nathan R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); McDaniel, Michael [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Schroeppel, Richard C. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Seager, Kevin D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Stoddard, Mary Clare [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); MacArthur, Duncan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2015-06-01

This report summarizes the discussion and conclusions reached during a table top exercise held at Sandia National Laboratories, Albuquerque on September 3, 2014 regarding a recently described approach for nuclear warhead verification based on the cryptographic concept of a zero-knowledge protocol (ZKP) presented in a recent paper authored by Glaser, Barak, and Goldston. A panel of Sandia National Laboratories researchers, whose expertise includes radiation instrumentation design and development, cryptography, and arms control verification implementation, jointly reviewed the paper and identified specific challenges to implementing the approach as well as some opportunities. It was noted that ZKP as used in cryptography is a useful model for the arms control verification problem, but the direct analogy to arms control breaks down quickly. The ZKP methodology for warhead verification fits within the general class of template-based verification techniques, where a reference measurement is used to confirm that a given object is like another object that has already been accepted as a warhead by some other means. This can be a powerful verification approach, but requires independent means to trust the authenticity of the reference warhead - a standard that may be difficult to achieve, which the ZKP authors do not directly address. Despite some technical challenges, the concept of last-minute selection of the pre-loads and equipment could be a valuable component of a verification regime.

The use of adaptive equipment following total knee replacement

OpenAIRE

McNaught, Jamie; Paul, Lorna

2015-01-01

Introduction: This study evaluates the need for adaptive equipment following total knee replacement. There are no recent studies to guide occupational therapists in the optimum time adaptive equipment is required following total knee replacement.\\ud \\ud Method: A non-experimental, concurrent mixed methods approach was used. The study population was patients attending for total knee replacement at a large general hospital. Outcome measures were the Oxford Knee Score, the United Kingdom Functio...

New energy replacement method for resonant power supplies

International Nuclear Information System (INIS)

Karady, G.G.; Thiessen, H.A.

1989-01-01

The Resonant Power Supply is an economically and technically advanced solution for Rapid Cycling Accelerators. Several papers dealt with the design and operation of these power supplies, however, the energy replacement methods were not discussed in the past. This paper analyzes different energy-replacement methods and presents a new method. This method uses a 24-pulse converter to regulate the magnet current during flat-top and injection periods and replaces the energy loss by charging the accelerator capacitor bank during the flat-top, reset and injection periods, charge is injected in the circuit during the acceleration period, when it replaces the energy loss. This paper compares the new method with the existing ones. The analyses proved the feasibility of the proposed method. The operation of the proposed method was verified by a model experiment, which showed that the new circuit can be controlled accurately and operates with smaller disturbances to the power line than the existing systems. 2 refs., 6 figs., 1 tab

Replacement Condition Detection of Railway Point Machines Using an Electric Current Sensor.

Science.gov (United States)

Sa, Jaewon; Choi, Younchang; Chung, Yongwha; Kim, Hee-Young; Park, Daihee; Yoon, Sukhan

2017-01-29

Detecting replacement conditions of railway point machines is important to simultaneously satisfy the budget-limit and train-safety requirements. In this study, we consider classification of the subtle differences in the aging effect-using electric current shape analysis-for the purpose of replacement condition detection of railway point machines. After analyzing the shapes of after-replacement data and then labeling the shapes of each before-replacement data, we can derive the criteria that can handle the subtle differences between "does-not-need-to-be-replaced" and "needs-to-be-replaced" shapes. On the basis of the experimental results with in-field replacement data, we confirmed that the proposed method could detect the replacement conditions with acceptable accuracy, as well as provide visual interpretability of the criteria used for the time-series classification.

Infective endocarditis following percutaneous pulmonary valve replacement

DEFF Research Database (Denmark)

Cheung, Gary; Vejlstrup, Niels; Ihlemann, Nikolaj

2013-01-01

Infective endocarditis (IE) following percutaneous pulmonary valve replacement (PPVR) with the Melody valve is rarely reported. Furthermore, there are challenges in this diagnosis; especially echocardiographic evidence of vegetation within the prosthesis may be difficult.......Infective endocarditis (IE) following percutaneous pulmonary valve replacement (PPVR) with the Melody valve is rarely reported. Furthermore, there are challenges in this diagnosis; especially echocardiographic evidence of vegetation within the prosthesis may be difficult....

Safety and efficacy of a multiphase dietetic protocol with meal replacements including a step with very low calorie diet.

Science.gov (United States)

Basciani, Sabrina; Costantini, Daniela; Contini, Savina; Persichetti, Agnese; Watanabe, Mikiko; Mariani, Stefania; Lubrano, Carla; Spera, Giovanni; Lenzi, Andrea; Gnessi, Lucio

2015-04-01

To investigate safety, compliance, and efficacy, on weight loss and cardiovascular risk factors of a multiphasic dietary intervention based on meal replacements, including a period of very low calorie diet (VLCD) in a population of obese patients. Anthropometric parameters, blood tests (including insulin), dual-energy-X-ray absorptiometry (DXA), and questionnaires for the assessment of safety and compliance before and after (phase I) a 30-day VLCD, 700 kcal/day, normoproteic, 50 g/day carbohydrate, four meal replacements; (phase II) a 30-day low calorie diet (LCD), 820 kcal/day, three meal replacements plus a protein plate; (phase III) 60-day LCD, 1,100 kcal/day, two meal replacements plus two protein plates and reintroduction of small amounts of carbohydrates; (phase IV) 60-day hypocaloric balanced diet (HBD), 1,200 kcal/day, one meal replacement, two protein plates and the reintroduction of carbohydrates. 24 patients (17 females, 7 males, mean BMI 33.8±3.2 kg/m2, mean age 35.1±10.2 years) completed the study. The average weight loss was 15.4±6.7%, with a significant reduction of fat mass (from 32.8±4.7 to 26.1±6.3% p<0.05) and a relative increase of lean mass (from 61.9±4.8 to 67.1±5.9% p<0.05). An improvement of metabolic parameters and no variations of the liver and kidney functions were found. A high safety profile and an excellent dietary compliance were seen. The VLCD dietary program and the replacement dietary system described here is an effective, safe, and well-tolerated treatment for weight control.

9 CFR 82.15 - Replacement birds and poultry.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Replacement birds and poultry. 82.15... AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS EXOTIC NEWCASTLE DIS- EASE (END) AND CHLAMYDIOSIS Exotic Newcastle Disease (END) § 82.15 Replacement birds and poultry. Birds...

30 CFR 57.12036 - Fuse removal or replacement.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Fuse removal or replacement. 57.12036 Section 57.12036 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND... Electricity Surface and Underground § 57.12036 Fuse removal or replacement. Fuses shall not be removed or...

On Foundation Improvement By Sand Replacement | Abam | Global ...

African Journals Online (AJOL)

This paper describes a simple foundation improvement method involving the replacement of poor foundation bearing soils with sand and the resultant improvement in bearing capacity and the minimization of settlement at the site of a large storage tank. Minimum thickness of sand replacement for various foundation loads ...

Optimization on replacement and inspection period of plant equipment

International Nuclear Information System (INIS)

Takase, Kentaro; Kasai, Masao

2004-01-01

Rationalization of the plant maintenance is one of the main topics being investigated in Japanese nuclear power industries. Optimization of the inspection and replacement period of equipments is effective for the maintenance cost reduction. The more realistic model of the replacement policy is proposed in this study. It is based on the classical replacement policy model and its cost is estimated. Then, to consider the inspection for the maintenance, the formulation that includes the risk concept is discussed. Based on it, two variations of the combination of the inspection and the replacement are discussed and the costs are estimated. In this study the effect of the degradation of the equipment is important. The optimized maintenance policy depends on the existence of significant degradation. (author)

30 CFR 872.29 - What are prior balance replacement funds?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 3 2010-07-01 2010-07-01 false What are prior balance replacement funds? 872... § 872.29 What are prior balance replacement funds? “Prior balance replacement funds” are moneys we must... general funds of the United States Treasury that are otherwise unappropriated. Under section 411(h)(1) of...

The cost function for the preventive - maintenance replacement problem

OpenAIRE

Vilaplana, Jose Perez

1994-01-01

Let a discounted continuous review preventive-maintenance replacement model be such that its total discounted cost is given by means of two functional equations. We assume that downtime is caused by equipment breakdowns, and the length of a given downtime is the time necessary to repair the equipment and set it back in operation. The periodic preventive replacement policy is to replace the equipment by a new identical equipment when service age X is reached, or when the equipment ...

U.S. oil-import vulnerability: The technical replacement capability

International Nuclear Information System (INIS)

1991-10-01

The report examines the changes that have taken place in world oil markets and the U.S. economy since 1984 and provides revised estimates of the technical oil replacement potential that might be attained in the event of a severe and long lasting cutoff of imported oil. The analysis focuses on technologies that are commercially available today or will be within the next 5 years and that are among the most cost-effective methods for replacing oil use in applicable sectors. It also considers the economic impacts of adopting an aggressive oil replacement strategy in a severe oil emergency. The report presents a variety of policy options that could help accelerate the adoption of oil replacement technologies in preparation for, or in response to, a severe supply disruption, or as part of a long-term national policy to reduce import vulnerability. The report concludes that U.S. capability to replace lost oil imports is shrinking. Market forces alone will not be sufficient to overcome the substantial economic and social dislocations that could result from a prolonged major oil disruption

Imaging techniques in transcatheter aortic valve replacement

Directory of Open Access Journals (Sweden)

Quaife RA

2013-11-01

Full Text Available Robert A Quaife, Jennifer Dorosz, John C Messenger, Ernesto E Salcedo Division of Cardiology, University of Colorado, Aurora, CO, USA Abstract: Calcific aortic stenosis is now understood as a complex valvular degenerative process sharing many risk factors with atherosclerosis. Once patients develop symptomatic calcific aortic stenosis, the only effective treatment is aortic valve replacement. In the past decade, transcatheter aortic valve replacement (TAVR has been developed as an alternative to surgery to treat severe calcific aortic stenosis. Cardiac imaging plays a pivotal role in the contemporary management of patients with calcific aortic stenosis, and particularly in patients being considered for TAVR, who demand detailed imaging of the aortic valve apparatus. In this review, we highlight the role of cardiac imaging for patient selection, procedural guidance, and evaluation of results of TAVR. Keywords: aortic stenosis, cardiovascular imaging, transcutaneous aortic valve replacement

Studies on the replacement policies in dairy cattle

NARCIS (Netherlands)

Arendonk, van J.A.M.

1985-01-01

In The Netherlands dairy farmers replace on average 25-30% of their cows each year. The decision to replace instead of to keep a cow is based mainly on economic considerations rather than because a cow is no longer able to produce.

The investigations described in this thesis were

22 CFR 42.74 - Issuance of new or replacement visas.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Issuance of new or replacement visas. 42.74... IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.74 Issuance of new or replacement...) Replacement immigrant visa for an immediate relative or for an alien subject to numerical limitation. (1) A...

Valve assembly having remotely replaceable bearings

International Nuclear Information System (INIS)

Johnson, E.R.; Tanner, D.E.

1980-01-01

A valve assembly having remotely replaceable bearings is disclosed wherein a valve disc is supported within a flow duct for rotation about a pair of axially aligned bearings, one of which is carried by a spindle received within a diametral bore in the valve disc, and the other of which is carried by a bearing support block releasably mounted on the duct circumferentially of an annular collar on the valve disc coaxial with its diametrical bore. The spindle and bearing support block are adapted for remote removal to facilitate servicing or replacement of the valve disc support bearings

ABWR evolution program

International Nuclear Information System (INIS)

Omoto, A.; Tanabe, A.; Moriya, K.; Dillmann, C.W.

1993-01-01

The ABWR plant is becoming a commercial reality in Japan where the first two units are being built by the Tokyo Electric Power Company. Although these units are scheduled to come on line in 1996 and '97, the Tokyo Electric Power Company, jointly with NSSS vendors (General Electric, Toshiba and Hitachi) and Japanese BWR utilities, initiated a program for a new plant design. This program is aimed at the further evolution of the ABWR to take advantage of new technological developments and to meet possible social changes in the years to come. The expected time for the first-of-a-kind plant to come on line is in the 2010's when the first generation plants in Japan may approach the time for replacement. This paper presents the ouline of this program with focus on the utility requirements and candidate technologies. (orig.)

Steam generator replacement at the Obrigheim nuclear power station

International Nuclear Information System (INIS)

Pickel, E.; Schenk, H.; Huemmler, A.

1984-01-01

The Obrigheim Nuclear Power Station (KWO) is equipped with a dual-loop pressurized water reactor of 345 MW electric power; it was built by Siemens in the period 1965 to 1968. By the end of 1983, KWO had produced some 35 billion kWh in 109,000 hours of operation. Repeated leaks in the heater tubes of the two steam generators had occurred since 1971. Both steam generators were replaced in the course of the 1983 annual revision. Kraftwerk Union AG (KWU) was commissioned to plant and carry out the replacement work. Despite the leakages the steam generators had been run safely and reliably over a period of 14 years until their replacement. Replacing the steam generators was completed within twelve weeks. In addition to the KWO staff and the supervising crew of KWU, some 400 external fitters were employed on the job at peak work-load periods. For the revision of the whole plant, work on the emergency systems and replacement of the steam generators a maximum number of approx. 900 external fitters were employed in the plant in addition to some 250 members of the plant crew. The exposure dose of the personnel sustained in the course of the steam generator replacement was 690 man-rem, which was clearly below previous estimates. (orig.) [de

Midterm Results of Aortic Valve Replacement with Cryopreserved Homografts

Directory of Open Access Journals (Sweden)

Emre Özker

2012-06-01

Full Text Available Objective: The aim of this study was to analyze the midterm clinical results of aortic valve replacement with cryopreserved homografts.Materials and Methods: Aortic valve replacement was performed in 40 patients with cryopreserved homograft. The indications were aortic valve endocarditis in 20 patients (50%, truncus arteriosus in 6 patients (15%, and re-stenosis or regurtitation after aortic valve reconstruction in 14 (35% patients. The valve sizes ranged from 10 to 27mm. A full root replacement technique was used for homograft replacement in all patients.Results: The 30-day postoperative mortality rate was 12.5% (5 patients. There were four late deaths. Only one of them was related to cardiac events. Overall mortality was 22.5%. Thirty-three patients were followed up for 67±26 months. Two patients needed reoperation due to aortic aneurysm caused by endocarditis. The mean transvalvular gradient significantly decreased after valve replacement (p<0.003. The last follow up showed that the 27 (82% patients had a normal left ventricular function.Conclusion: Cryopreserved homografts are safe alternatives to mechanical valves that can be used when there are proper indications. Although it has a high perioperative mortality rate, cryopreserved homograft implantation is an alternative for valve replacement, particularly in younger patients and for complex surgical problems such as endocarditis that must be minimalized.

Esophageal replacement in children: Challenges and long-term outcomes

Directory of Open Access Journals (Sweden)

Giampiero Soccorso

2016-01-01

Full Text Available Replacement of a nonexistent or damaged esophagus continues to pose a significant challenge to pediatric surgeons. Various esophageal replacement grafts and techniques have not produced consistently good outcomes to emulate normal esophagus. Therefore, many techniques are still being practiced and recommended with no clear consensus. We present a concise literature review of the currently used techniques and with discussions on the advantages and anticipated morbidity. There are no randomized controlled pediatric studies to compare different types of esophageal replacements. Management and graft choice are based on geographical and personal predilections rather than on any discernible objective data. The biggest series with long-term outcome are reported for gastric transposition and colonic replacement. Comparison of different studies shows no significant difference in early (graft necrosis and anastomotic leaks or late complications (strictures, poor feeding, gastro-esophageal reflux, tortuosity of the graft, and Barrett′s esophagus. The biggest series seem to have lower complications than small series reflecting the decennials experience in their respective centers. Long-term follow-up is recommended following esophageal replacement for the development of late strictures, excessive tortuosity, and Barrett′s changes within the graft. Once child overcomes initial morbidity and establishes oral feeding, long-term consequences and complications of pediatric esophageal replacement should be monitored and managed in adult life.

Does Online Marketing Truly Replace Traditional Marketing?

OpenAIRE

Gunawan, Emilia Margareth

2013-01-01

This review explains the way how online marketing has been replacing traditional marketing in terms of marketing mix. This replacement might happen, because online marketing can give advantages, i.e., offering on-time delivery, increasing effectiveness of two way interactions between buyer and seller, and creating online communities (Szmigin, et al, 2005). The transition of atoms to bits format reflects that tangible products in traditional marketing is being digitalized. The marketing strate...

The role of congress in future disposal of fissile materials from dismantled nuclear weapons

International Nuclear Information System (INIS)

Donnelly, W.H.; Davis, Z.S.

1991-01-01

Assuming the Soviet Union remains intact as a major power and the superpowers do not retrogress to a new Cold War era, it is likely that the United States and the Soviet Union will eventually agree to deep cuts in their nuclear arsenals. Future arms control agreements may be coupled with companion agreements to stop production of fissile materials for nuclear weapons, to dismantle the warheads of the nuclear weapons, and to dispose of their fissile materials to prevent reuse in new warheads. Such agreements would be negotiated by the U.S. executive branch but probably would require ratification, funding, and enabling legislation from the U.S. Congress if they are to succeed. There follows a brief review of the ideas for disposal of fissile materials from dismantled nuclear warheads and the potential role and influence of the Congress in the negotiation, ratification, and implementation of U.S.-Soviet agreements for such disposal

Meal Replacement Mass Reduction Integration and Acceptability Study

Science.gov (United States)

Sirmons, T.; Douglas, G.; Schneiderman, J.; Slack, K.; Whitmire, A.; Williams, T.; Young, M.

2018-01-01

The Orion Multi-Purpose Crew Vehicle (MPCV) and future exploration missions are mass constrained; therefore we are challenged to reduce the mass of the food system by 10% while maintaining safety, nutrition, and acceptability to support crew health and performance for exploration missions. Meal replacement with nutritionally balanced, 700-900 calorie bars was identified as a method to reduce mass. However, commercially available products do not meet the requirements for a meal replacement in the spaceflight food system. The purpose of this task was to develop a variety of nutritionally balanced, high quality, breakfast replacement bars, which enable a 10% food mass savings. To date, six nutrient-dense meal replacement bars have been developed, all of which meet spaceflight nutritional, microbiological, sensory, and shelf-life requirements. The four highest scoring bars were evaluated based on final product sensory acceptability, nutritional stability, qualitative stability of analytical measurements (i.e. color and texture), and microbiological compliance over a period of two years to predict long-term acceptability. All bars maintained overall acceptability throughout the first year of storage, despite minor changes in color and texture. However, added vitamins C, B1, and B9 degraded rapidly in fortified samples of Banana Nut bars, indicating the need for additional development. In addition to shelf-life testing, four bar varieties were evaluated in the Human Exploration Research Analog (HERA), campaign 3, to assess the frequency with which actual meal replacement options may be implemented, based on impact to satiety and psychosocial measurements. Crewmembers (n=16) were asked to consume meal replacement bars every day for the first fifteen days of the mission and every three days for the second half of the mission. Daily surveys assessed the crew's responses to bar acceptability, mood, food fatigue and perceived stress. Preliminary results indicate that the

Frequency of pacemaker malfunction associated with monopolar electrosurgery during pulse generator replacement or upgrade surgery.

Science.gov (United States)

Lin, Yun; Melby, Daniel P; Krishnan, Balaji; Adabag, Selcuk; Tholakanahalli, Venkatakrishna; Li, Jian-Ming

2017-08-01

The aim of this study is to investigate the frequency of electrosurgery-related pacemaker malfunction. A retrospective study was conducted to investigate electrosurgery-related pacemaker malfunction in consecutive patients undergoing pulse generator (PG) replacement or upgrade from two large hospitals in Minneapolis, MN between January 2011 and January 2014. The occurrence of this pacemaker malfunction was then studied by using MAUDE database for all four major device vendors. A total of 1398 consecutive patients from 2 large tertiary referral centers in Minneapolis, MN undergoing PG replacement or upgrade surgery were retrospectively studied. Four patients (0.3% of all patients), all with pacemakers from St Jude Medical (2.8%, 4 of 142) had output failure or inappropriately low pacing rate below 30 bpm during electrosurgery, despite being programmed in an asynchronous mode. During the same period, 1174 cases of pacemaker malfunctions were reported on the same models in MAUDE database, 37 of which (3.2%) were electrosurgery-related. Twenty-four cases (65%) had output failure or inappropriate low pacing rate. The distribution of adverse events was loss of pacing (59.5%), reversion to backup pacing (32.4%), inappropriate low pacing rate (5.4%), and ventricular fibrillation (2.7%). The majority of these (78.5%) occurred during PG replacement at ERI or upgrade surgery. No electrosurgery-related malfunction was found in MAUDE database on 862 pacemaker malfunction cases during the same period from other vendors. Electrosurgery during PG replacement or upgrade surgery can trigger output failure or inappropriate low pacing rate in certain models of modern pacemakers. Cautions should be taken for pacemaker-dependent patients.

Joint Replacement Surgery: Health Information Basics for You and Your Family

Science.gov (United States)

... Initiative Breadcrumb Home Health Topics English Español Joint Replacement Surgery Basics In-Depth Download Download EPUB Download ... What is it? Points To Remember About Joint Replacement Surgery Joint replacement surgery removes damaged or diseased ...

42 CFR 84.194 - Filters used with chemical cartridges; location; replacement.

Science.gov (United States)

2010-10-01

...; replacement. 84.194 Section 84.194 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN...; replacement. (a) Particulate matter filters used in conjunction with a chemical cartridge shall be located on... replacement on the cartridge. ...

Modifications to Replacement Costs System

International Nuclear Information System (INIS)

Godec, M.

1989-01-01

The purpose of this memorandum is to document the improvements and modifications made to the Replacement Costs of Crude Oil (REPCO) Supply Analysis System. While some of this work was performed under our previous support contract to DOE/ASFE, we are presenting all modifications and improvements are presented here for completeness. The memo primarily documents revisions made to the Lower-48 Onshore Model. Revisions and modifications made to other components and models in the REPCO system which are documented elsewhere are only highlighted in this memo. Generally, the modifications made to the Lower-48 Onshore Model reflect changes that have occurred in domestic drilling, oil field costs, and reserves since 1982, the date of the most recent available data used for the original Replacement Costs report, published in 1985

Investigation of gamma spectra analysis

International Nuclear Information System (INIS)

Wu Huailong; Liu Suping; Hao Fanhua

2006-12-01

During the investigation of radiation fingerprint comparison, it is found out that the popular gamma spectra analysis softwares are faultful, which decrease the precision of radiation fingerprint comparison. So a new analysis software is development for solving the problems. In order to display the advantage of new program, some typical simulative gamma spectra of radiation source are analyzed respectively by our software and GAMMAVISION and GENNIE2000. The software can be applied not only in nuclear warheads deep-cuts verification, but also in any radiation measurement field. (authors)

A lifecycle management program for NPP turbine balance of plant

International Nuclear Information System (INIS)

Manabe, Jun; Yamakami, Katsuhiko; Hiraoka, Satoshi; Kawai, Toshinari

2009-01-01

A lifecycle management program, for turbine balance of plant of light water reactor units which had been operated for more than 20 years but still having a long intended residual life time, was proposed and implemented from the view point of system and equipment supplier. Here would be introduced the program executed for several utilities. The program consists of unit surveillance analyzing both operation and inspection data, degradation assessment for the equipment and prospecting for the future by planning the proper measures for the issues based on both technology and economy. The program is introduced exampling the generating power affected by main steam pressure reduction derived from the scale adhesion and degradation of equipment. Multidisciplinary optimum design for the replacement of the feedwater heaters, one of the items of the planning, is introduced. Additionally would be introduced the new concept maintenance support program, mainly applied to the units already replaced their principal machines and auxiliaries, configured with both the condition based maintenance system monitoring the trend of parameters of a component and the diagnosis of malfunctions ascertaining the equipment by analyzing and synthesizing operation parameters. (author)

Effects of replacing lactose from milk replacer by glucose, fructose, or glycerol on energy partitioning in veal calves.

Science.gov (United States)

Gilbert, M S; Pantophlet, A J; van den Borne, J J G C; Hendriks, W H; Schols, H A; Gerrits, W J J

2016-02-01

Calf milk replacers contain 40 to 50% lactose. Fluctuating dairy prices are a major economic incentive to replace lactose from milk replacers by alternative energy sources. Our objective was, therefore, to determine the effects of replacement of lactose with glucose, fructose, or glycerol on energy and protein metabolism in veal calves. Forty male Holstein-Friesian calves (114±2.4 kg) were fed milk replacer containing 46% lactose (CON) or 31% lactose and 15% of glucose (GLUC), fructose (FRUC), or glycerol (GLYC). Solid feed was provided at 10 g of dry matter (DM)/kg of metabolic body weight (BW(0.75)) per day. After an adaptation of 48 d, individual calves were harnessed, placed in metabolic cages, and housed in pairs in respiration chambers. Apparent total-tract disappearance of DM, energy, and N and complete energy and N balances were measured. The GLUC, FRUC, and GLYC calves received a single dose of 1.5 g of [U-(13)C]glucose, [U-(13)C]fructose, or [U-(13)C]glycerol, respectively, with their milk replacer at 0630 h and exhaled (13)CO2 and (13)C excretion with feces was measured. Apparent total-tract disappearance was decreased by 2.2% for DM, 3.2% for energy, and 4.2% for N in FRUC compared with CON calves. Energy and N retention did not differ between treatments, and averaged 299±16 kJ/kg of BW(0.75) per day and 0.79±0.04 g/kg of BW(0.75) per day, respectively, although FRUC calves retained numerically less N (13%) than other calves. Recovery of (13)C isotopes as (13)CO2 did not differ between treatments and averaged 72±1.6%. The time at which the maximum rate of (13)CO2 production was reached was more than 3 h delayed for FRUC calves, which may be explained by a conversion of fructose into other substrates before being oxidized. Recovery of (13)C in feces was greater for FRUC calves (7.7±0.59%) than for GLUC (1.0±0.27%) and GLYC calves (0.5±0.04%), indicating incomplete absorption of fructose from the small intestine resulting in fructose excretion or

Prevalence of Total Hip and Knee Replacement in the United States.

Science.gov (United States)

Maradit Kremers, Hilal; Larson, Dirk R; Crowson, Cynthia S; Kremers, Walter K; Washington, Raynard E; Steiner, Claudia A; Jiranek, William A; Berry, Daniel J

2015-09-02

Descriptive epidemiology of total joint replacement procedures is limited to annual procedure volumes (incidence). The prevalence of the growing number of individuals living with a total hip or total knee replacement is currently unknown. Our objective was to estimate the prevalence of total hip and total knee replacement in the United States. Prevalence was estimated using the counting method by combining historical incidence data from the National Hospital Discharge Survey and the Healthcare Cost and Utilization Project (HCUP) State Inpatient Databases from 1969 to 2010 with general population census and mortality counts. We accounted for relative differences in mortality rates between those who have had total hip or knee replacement and the general population. The 2010 prevalence of total hip and total knee replacement in the total U.S. population was 0.83% and 1.52%, respectively. Prevalence was higher among women than among men and increased with age, reaching 5.26% for total hip replacement and 10.38% for total knee replacement at eighty years. These estimates corresponded to 2.5 million individuals (1.4 million women and 1.1 million men) with total hip replacement and 4.7 million individuals (3.0 million women and 1.7 million men) with total knee replacement in 2010. Secular trends indicated a substantial rise in prevalence over time and a shift to younger ages. Around 7 million Americans are living with a hip or knee replacement, and consequently, in most cases, are mobile, despite advanced arthritis. These numbers underscore the substantial public health impact of total hip and knee arthroplasties. Copyright © 2015 by The Journal of Bone and Joint Surgery, Incorporated.

33 CFR 1.26-5 - Replacement of medals.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Replacement of medals. 1.26-5 Section 1.26-5 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY GENERAL... Rentals § 1.26-5 Replacement of medals. (a) A medal, or a bar, emblem, or insignia in lieu thereof, that...

Steam generator replacement at Bruce A: approach, results, and lessons learned

International Nuclear Information System (INIS)

Tomkiewicz, W.; Savage, B.; Smith, J.

2008-01-01

Steam Generator Replacement is now complete in Bruce A Units 1 and 2. In each reactor, eight steam generators were replaced; these were the first CANDU steam generator replacements performed anywhere in the world. The plans for replacement were developed in 2004 and 2005, and were summarized in an earlier paper for the CNS Conference held in November, 2006. The present paper briefly summarizes the methodologies and special processes used such as metrology, cutting and welding and heavy lifting. The paper provides an update since the earlier report and focuses on the project achievements to date, such as: - A combination of engineered methodology, laser metrology and precise remote machining led to accurate first time fit-ups of each new replacement steam generator and steam drums - Lessons learned in the first unit led to schedule improvements in the second unit - Dose received was lowest recorded for any steam generator replacement project. The experience gained and lessons learned from Units 1 and 2 will be valuable in planning and executing future replacement steam generator projects. A video was presented

Upgrade programs. Status and prospective

International Nuclear Information System (INIS)

Loyer, F.

1998-01-01

Arguments for launching a renovation program for GANIL system, taking into account aging and wear, are analyzed. A statistics of failures related to vacuum systems, power supplies, electronics, cooling systems, beam dumps and other equipment is given. The renovation program is targeted to: replacement of obsolete components, introduction of advanced systems of failure diagnosis, augmentation of performances of the new regulating and control system and improvement in the performance characteristics of certain fundamental equipment. The first results and to date status of the program development is reported. Mentioned are the works related to control of HF cavities and the associated amplifiers, electronics, the system of cavity synchronization, power supply, RMN, system commutation grid, pumping equipment, etc. Also, improvements concerning the machine data acquisition and online processing are referred to as well as program cost estimations

Machine replacement, Network Externalities and Investment Cycles

OpenAIRE

Juan Ruiz

2003-01-01

This paper presents a model where agents decide on the timing of replacement of ageing machines. The optimal replacement policy for an agent is influenced by other agents' decisions because the productivity of a particular vintage displays network externalities that set in with a lag. In equilibrium, agents follow innovation cycles with a frequency that is lower than optimal, so there is too much delay. One extreme case is the possibility of inefficient collapse: for some parameters there is ...

OPTIMIZATION MODEL FOR VEHICLE ROUTING AND EQUIPMENT REPLACEMENT IN FARM MACHINERY

OpenAIRE

Grano, Carolina; Abensur, Eder

2017-01-01

ABSTRACT: An equipment replacement decision takes into account economic engineering models based on discounted cash flow (DCF) such as the Annual Equivalent Cost (AEC). Despite a large number of researches on industrial assets replacement, there is a lack of studies applied to farm goods. This study aimed at assessing an alternative model for economic decision analysis on farm machinery replacement, with no restrictions on the number of replacements and assessed goods during a defined timelin...

REPLACEMENT OF FRENCH CARDS

CERN Multimedia

Human Resources Division

2001-01-01

The French Ministry of Foreign Affairs has informed the Organization that it is shortly to replace all diplomatic cards, special cards and employment permits ('attestations de fonctions') now held by members of the personnel and their families. Between 2 July and 31 December 2001, these cards are to be replaced by secure, computerized equivalents. A 'personnel office' stamped photocopy of the old cards may continue to be used until 31 December 2001. For the purposes of the handover, members of the personnel must go personally to the cards office (33/1-015), between 8:30 and 12:30, in order to fill a 'fiche individuelle' form (in black ink only), which has to be personally signed by themselves and another separately signed by members of their family, taking the following documents for themselves and members of their families already in possession of a French card : A recent identity photograph in 4.5 cm x 3.5 cm format (signed on the back) The French card in their possession an A4 photocopy of the same Fre...

Power Plant Replacement Study

Energy Technology Data Exchange (ETDEWEB)

Reed, Gary

2010-09-30

This report represents the final report for the Eastern Illinois University power plant replacement study. It contains all related documentation from consideration of possible solutions to the final recommended option. Included are the economic justifications associated with the chosen solution along with application for environmental permitting for the selected project for construction. This final report will summarize the results of execution of an EPC (energy performance contract) investment grade audit (IGA) which lead to an energy services agreement (ESA). The project includes scope of work to design and install energy conservation measures which are guaranteed by the contractor to be self-funding over its twenty year contract duration. The cost recovery is derived from systems performance improvements leading to energy savings. The prime focus of this EPC effort is to provide a replacement solution for Eastern Illinois University's aging and failing circa 1925 central steam production plant. Twenty-three ECMs were considered viable whose net impact will provide sufficient savings to successfully support the overall project objectives.

Power Plant Replacement Study

Energy Technology Data Exchange (ETDEWEB)

Reed, Gary

2010-09-30

This report represents the final report for the Eastern Illinois University power plant replacement study. It contains all related documentation from consideration of possible solutions to the final recommended option. Included are the economic justifications associated with the chosen solution along with application for environmental permitting for the selected project for construction. This final report will summarize the results of execution of an EPC (energy performance contract) investment grade audit (IGA) which lead to an energy services agreement (ESA). The project includes scope of work to design and install energy conservation measures which are guaranteed by the contractor to be self-funding over its twenty year contract duration. The cost recovery is derived from systems performance improvements leading to energy savings. The prime focus of this EPC effort is to provide a replacement solution for Eastern Illinois University’s aging and failing circa 1925 central steam production plant. Twenty-three ECMs were considered viable whose net impact will provide sufficient savings to successfully support the overall project objectives.

Extended replacement of the thoracic aorta.

Science.gov (United States)

Hino, Yutaka; Okada, Kenji; Oka, Takanori; Inoue, Takeshi; Tanaka, Akiko; Omura, Atsushi; Kano, Hiroya; Okita, Yutaka

2013-01-01

We present our experience of total aortic arch replacement. Twenty-nine patients (21 males and 8 females; mean age 63.3 ± 13.3 years) with extended thoracic aortic aneurysms underwent graft replacement. The pathology of the diseased aorta was non-dissecting aneurysm in 11 patients, including one aortitis and aortic dissection in 18 patients (acute type A: one, chronic type A: 11, chronic type B: six). Five patients had Marfan syndrome. In their previous operation, two patients had undergone the Bentall procedure, three had endovascular stenting, one had aortic root replacement with valve sparing and 12 had hemi-arch replacement for acute type A dissection. Approaches to the aneurysm were as follows: posterolateral thoracotomy with rib-cross incision in 16, posterolateral thoracotomy extended to the retroperitoneal abdominal aorta in seven, mid-sternotomy and left pleurotomy in three, anterolateral thoracotomy with partial lower sternotomy in two and clam-shell incision in one patient. Extension of aortic replacement was performed from the aortic root to the descending aorta in 4, from the ascending aorta to the descending aorta in 17 and from the ascending to the abdominal aorta in eight patients. Arterial inflow for cardiopulmonary bypass consisted of the femoral artery in 15 patients, ascending aorta and femoral artery in seven, descending or abdominal aorta in five and ascending aorta in two. Venous drainage site was the femoral vein in 10, pulmonary artery in eight, right atrium in five, femoral artery with right atrium/pulmonary artery in four and pulmonary artery with right atrium in two patients. The operative mortality, 30-day mortality and hospital mortality was one (cardiac arrest due to aneurysm rupture), one (rupture of infected aneurysm) and one (brain contusion), respectively. Late mortality occurred in three patients due to pneumonia, ruptured residual aneurysm and intracranial bleeding. Actuarial survival at 5 years after the operations was 80.6 �

Analysis and optimization of trajectories for Ballistic Missiles Interception

OpenAIRE

Montero Yéboles, Daniel

2016-01-01

Intercontinental Ballistic Missiles are capable of placing a nuclear warhead at more than 5,000 km away from its launching base. With the lethal power of a nuclear warhead a whole city could be wiped out by a single weapon causing millions of deaths. This means that the threat posed to any country from a single ICBM captured by a terrorist group or launched by a 'rogue' state is huge. This threat is increasing as more countries are achieving nuclear and advanced launcher capabilities. In orde...

Slab replacement maturity guidelines : [summary].

Science.gov (United States)

2014-04-01

Concrete sets in hours at moderate temperatures, : but the bonds that make concrete strong continue : to mature over days to years. However, for : replacement concrete slabs on highways, it is : crucial that concrete develop enough strength : within ...

Antibiotic Dosing in Continuous Renal Replacement Therapy.

Science.gov (United States)

Shaw, Alexander R; Mueller, Bruce A

2017-07-01

Appropriate antibiotic dosing is critical to improve outcomes in critically ill patients with sepsis. The addition of continuous renal replacement therapy makes achieving appropriate antibiotic dosing more difficult. The lack of continuous renal replacement therapy standardization results in treatment variability between patients and may influence whether appropriate antibiotic exposure is achieved. The aim of this study was to determine if continuous renal replacement therapy effluent flow rate impacts attaining appropriate antibiotic concentrations when conventional continuous renal replacement therapy antibiotic doses were used. This study used Monte Carlo simulations to evaluate the effect of effluent flow rate variance on pharmacodynamic target attainment for cefepime, ceftazidime, levofloxacin, meropenem, piperacillin, and tazobactam. Published demographic and pharmacokinetic parameters for each antibiotic were used to develop a pharmacokinetic model. Monte Carlo simulations of 5000 patients were evaluated for each antibiotic dosing regimen at the extremes of Kidney Disease: Improving Global Outcomes guidelines recommended effluent flow rates (20 and 35 mL/kg/h). The probability of target attainment was calculated using antibiotic-specific pharmacodynamic targets assessed over the first 72 hours of therapy. Most conventional published antibiotic dosing recommendations, except for levofloxacin, reach acceptable probability of target attainment rates when effluent rates of 20 or 35 mL/kg/h are used. Copyright © 2017 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

Delay in onset of metabolic alkalosis during regional citrate anti-coagulation in continous renal replacement therapy with calcium-free replacement solution

Directory of Open Access Journals (Sweden)

See Kay

2009-01-01

Full Text Available Regional citrate anti-coagulation for continuous renal replacement therapy chelates calcium to produce the anti- coagulation effect. We hypothesise that a calcium-free replacement solution will require less citrate and produce fewer metabolic side effects. Fifty patients, in a Medical Intensive Care Unit of a tertiary teaching hospital (25 in each group, received continuous venovenous hemofiltration using either calcium-containing or calcium-free replacement solutions. Both groups had no significant differences in filter life, metabolic alkalosis, hypernatremia, hypocalcemia, and hypercalcemia. However, patients using calcium-containing solution developed metabolic alkalosis earlier, compared to patients using calcium-free solution (mean 24.6 hours,CI 0.8-48.4 vs. 37.2 hours, CI 9.4-65, P = 0.020. When calcium-containing replacement solution was used, more citrate was required (mean 280ml/h, CI 227.2-332.8 vs. 265ml/h, CI 203.4-326.6, P = 0.069, but less calcium was infused (mean 21.2 ml/h, CI 1.2-21.2 vs 51.6ml/h, CI 26.8-76.4, P ≤ 0.0001.

15 CFR 740.10 - Servicing and replacement of parts and equipment (RPL).

Science.gov (United States)

2010-01-01

... REGULATIONS LICENSE EXCEPTIONS § 740.10 Servicing and replacement of parts and equipment (RPL). This License... replacement of equipment. (a) Parts—(1) Scope. The provisions of this paragraph (a) authorize the export and reexport of one-for-one replacement parts for previously exported equipment. (2) One-for-one replacement of...

CINDA-3G: Improved Numerical Differencing Analyzer Program for Third-Generation Computers

Science.gov (United States)

Gaski, J. D.; Lewis, D. R.; Thompson, L. R.

1970-01-01

The goal of this work was to develop a new and versatile program to supplement or replace the original Chrysler Improved Numerical Differencing Analyzer (CINDA) thermal analyzer program in order to take advantage of the improved systems software and machine speeds of the third-generation computers.

Structural Evaluation of the RSRM Nozzle Replacement Adhesive

Science.gov (United States)

Batista-Rodriguez, A.; McLennan, M. L.; Palumbos, A. V.; Richardson, D. E.

1999-01-01

This paper describes the structural performance evaluation of a replacement adhesive for the Reusable Solid Rocket Motor (RSRM) nozzle utilizing finite element analysis. Due to material obsolescence and industrial safety issues, the two current structural adhesives, EA 913 and EA 946 are to be replaced with a new adhesive. TIGA 321. The structural evaluation in support of the adhesive replacement effort includes residual stress, transportation, and flight analyses. Factors of safety are calculated using the stress response from each analysis. The factors of safety are used as the limiting criteria to compare the replacement adhesive against the current adhesives. Included in this paper are the analytical approach, assumptions and modeling techniques as well as the results of the evaluation. An important factor to the evaluation is the similarity in constitutive material properties (elastic modulus and Poisson's ratio) between TIGA 321 and EA 913. This similarity leads to equivalent material response from the two adhesives. However, TIGA 321 surpasses EA 913's performance due to higher material capabilities. Conversely, the change in stress response from EA 946 to TIGA 321 is more apparent: this is primarily attributed to the difference in the modulii of the two adhesives, which differ by two orders of magnitude. The results of the bondline evaluation indicate that the replacement adhesive provides superior performance than the current adhesives with only minor exceptions. Furthermore, TIGA 321 causes only a minor chance in the response of the phenolic and metal components.

Program evaluation: Weatherization Residential Assistance Partnership (WRAP) Program

Energy Technology Data Exchange (ETDEWEB)

1991-12-01

The Connecticut low income weatherization program was developed in response to a 1987 rate docket order from the Connecticut Department of Public Utility Control (DPUC) to Connecticut Light Power Co., an operating subsidiary of Northeast Utilities (NU). (Throughout this report, NU is referred to as the operator of the program.) This program, known as the Weatherization Residential Assistance Partnership, or WRAP, was configured utilizing input from a collaborative group of interested parties to the docket. It was agreed that this program would be put forth by the electric utility, but would not ignore oil and gas savings (thus, it was to be fuel- blind''). The allocated cost of conservation services for each fuel source, however, should be cost effective. It was to be offered to those utility customers at or below 200 percent of the federal poverty levels, and provide a wide array of energy saving measures directed toward heating, water heating and lighting. It was felt by the collaborative group that this program would raise the level of expenditures per participant for weatherization services provided by the state, and by linking to and revising the auditing process for weatherization, would lower the audit unit cost. The program plans ranged from the offering of low-cost heating, water heating and infiltration measures, increased insulation levels, carpentry and plumbing services, to furnace or burner replacement. The program was configured to allow for very comprehensive weatherization and heating system servicing.

Hormone replacement therapy increases the risk of cranial meningioma

DEFF Research Database (Denmark)

Andersen, Lene; Friis, Søren; Hallas, Jesper

2013-01-01

We investigated the influence of hormone replacement therapy (HRT) use on the risk of meningioma in a population-based setting.......We investigated the influence of hormone replacement therapy (HRT) use on the risk of meningioma in a population-based setting....

Advances in the replacement and enhanced replacement method in QSAR and QSPR theories.

Science.gov (United States)

Mercader, Andrew G; Duchowicz, Pablo R; Fernández, Francisco M; Castro, Eduardo A

2011-07-25

The selection of an optimal set of molecular descriptors from a much greater pool of such regression variables is a crucial step in the development of QSAR and QSPR models. The aim of this work is to further improve this important selection process. For this reason three different alternatives for the initial steps of our recently developed enhanced replacement method (ERM) and replacement method (RM) are proposed. These approaches had previously proven to yield near optimal results with a much smaller number of linear regressions than the full search. The algorithms were tested on four different experimental data sets, formed by collections of 116, 200, 78, and 100 experimental records from different compounds and 1268, 1338, 1187, and 1306 molecular descriptors, respectively. The comparisons showed that one of the new alternatives further improves the ERM, which has shown to be superior to genetic algorithms for the selection of an optimal set of molecular descriptors from a much greater pool. The new proposed alternative also improves the simpler and the lower computational demand algorithm RM.

21 CFR 874.3540 - Prosthesis modification instrument for ossicular replacement surgery.

Science.gov (United States)

2010-04-01

... replacement surgery. 874.3540 Section 874.3540 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... § 874.3540 Prosthesis modification instrument for ossicular replacement surgery. (a) Identification. A prosthesis modification instrument for ossicular replacement surgery is a device intended for use by a...

Changing of the guard: reducing infection when replacing neural pacemakers.

Science.gov (United States)

Pepper, Joshua; Meliak, Lara; Akram, Harith; Hyam, Jonathan; Milabo, Catherine; Candelario, Joseph; Foltynie, Thomas; Limousin, Patricia; Curtis, Carmel; Hariz, Marwan; Zrinzo, Ludvic

2017-04-01

OBJECTIVE Infection of deep brain stimulation (DBS) hardware has a significant impact on patient morbidity. Previous experience suggests that infection rates appear to be higher after implantable pulse generator (IPG) replacement surgery than after the de novo DBS procedure. In this study the authors examine the effect of a change in practice during DBS IPG replacements at their institution. METHODS Starting in January 2012, patient screening for methicillin-resistant Staphylococcus aureus (MRSA) and, and where necessary, eradication was performed prior to elective DBS IPG change. Moreover, topical vancomycin was placed in the IPG pocket during surgery. The authors then prospectively examined the infection rate in patients undergoing DBS IPG replacement at their center over a 3-year period with at least 9 months of follow-up. RESULTS The total incidence of infection in this prospective consecutive series of 101 IPG replacement procedures was 0%, with a mean follow-up duration of 24 ± 11 months. This was significantly lower than the authors' previously published historical control group, prior to implementing the change in practice, where the infection rate for IPG replacement was 8.5% (8/94 procedures; p = 0.003). CONCLUSIONS This study suggests that a change in clinical practice can significantly lower infection rates in patients undergoing DBS IPG replacement. These simple measures can minimize unnecessary surgery, loss of benefit from chronic stimulation, and costly hardware replacement, further improving the cost efficacy of DBS therapies.

Optimization of hip joint replacement location to decrease maximum von Mi ses Stress

International Nuclear Information System (INIS)

Pourjamali, H.; Najarian, S.; Katoozian, H. R.

2001-01-01

Hip replacement is used for inoperable femur head injuries and femur fractures where internal fixation can not be used. This operation is one of the most common orthopedic operations that many research have been done about it. Among these we can mention implant and cement materials and composites optimization and also implant shape optimization. This study was designed to optimize artificial hip joint position (placement) to decrease maximal von mi sees stress. First, a model of femur and implant were made and then a computer program was written with the ability to change the position of implant through an acceptable range in the femur. In each of these positions, the program simulated femur and implant according to finite element method and made, applied forces were weight and muscle traction. Our findings show that a small deviation of the implant from femur bone center causes a considerable decrease in von mi sees stress that consequently results in longer maintenance of the implant

Navy Columbia Class (Ohio Replacement) Ballistic Missile Submarine (SSBN[X]) Program: Background and Issues for Congress

Science.gov (United States)

2016-08-18

25 Legislative Activity for FY2017...of 14 Ohio-class SSBNs, all of which are armed with D-5 SLBMs. Eight of the 14 Ohio-class SSBNs are homeported at Bangor, WA , in Puget Sound; the...Navy’s plan to design and procure Columbia- class boats. Columbia Class Program Program Name For several years, the Columbia class program was known

76 FR 30369 - Announcement of the Award of a Replacement Grant

Science.gov (United States)

2011-05-25

... the Award of a Replacement Grant AGENCY: Office of Community Services (OCS), ACF, DHHS. ACTION: Announcement of the award of a replacement grant from the Office of Community Services to Humboldt State... Services (OCS), announces the award of a replacement grant under the Strengthening Communities Fund (SCF...

Opportunity-based age replacement: exponentially distributed times between opportunities

NARCIS (Netherlands)

R. Dekker (Rommert); M.C. Dijkstra (Matthijs)

1992-01-01

textabstractThis article gives a full analysis of a component-replacement model in which preventive replacements are only possible at maintenance opportunities. These oppertunities arise according to a Poisson process, independently of failures of the component. Conditions for the existence of a

Excellence in fleet combat replacement squadrons: predicting carrier qualification success

OpenAIRE

Smith, Martin P.

1988-01-01

This thesis presents a two-part analysis of excellence criteria for fleet combat replacement squadrons. Part one focuses on the qualitative issues and management techniques identified in outstanding fleet combat replacement squadrons. Part two develops and presents a regression model for predicting a fleet replacement squadron pilot's carrier qualification grade. The model was derived using standard linear regression techniques and the SPSSx software package of the Naval Postgraduate School. ...

An approach to solve replacement problems under intuitionistic fuzzy nature

Science.gov (United States)

Balaganesan, M.; Ganesan, K.

2018-04-01

Due to impreciseness to solve the day to day problems the researchers use fuzzy sets in their discussions of the replacement problems. The aim of this paper is to solve the replacement theory problems with triangular intuitionistic fuzzy numbers. An effective methodology based on fuzziness index and location index is proposed to determine the optimal solution of the replacement problem. A numerical example is illustrated to validate the proposed method.

Replacement of major nuclear power plant components for service life extension

International Nuclear Information System (INIS)

Novak, S.

1987-01-01

Problems are discussed associated with replacement of nuclear power plant components with the aim to extend their original scheduled life. The existing foreign experience shows that it is technically feasible to replace practically all basic components for which the necessity of replacement is established. Data is summed up on the replacement of steam generators in US and West German nuclear power plants showing the duration of the job, the total consumption of manhours, the collective dose equivalent and the cost. Attention is also focused on implemented and projected replacements of circulation pipes in nuclear power plants abroad. Based on these figures, the cost is estimated of the replacement of the reactor vessel and the steam generators for WWER-440 nuclear power plants. The conclusion is arrived at that even based on a conservative estimate, the extension by 20 years of the service life of a nuclear power plant is economically more effective than the construction of a new plant. (Z.M.) 2 tabs., 15 refs., 3 figs

Effects of varenicline and nicotine replacement therapy on arterial elasticity, endothelial glycocalyx and oxidative stress during a 3-month smoking cessation program.

Science.gov (United States)

Ikonomidis, Ignatios; Marinou, Margarita; Vlastos, Dimitrios; Kourea, Kallirhoe; Andreadou, Ioanna; Liarakos, Nikolaos; Triantafyllidi, Helen; Pavlidis, George; Tsougos, Elias; Parissis, John; Lekakis, John

2017-07-01

The effects of medically-aided smoking cessation on vascular function and oxidative stress are not fully clarified. One hundred eighty-eight current smokers were randomized to varenicline or nicotine replacement treatment (NRT) for a 3-month period. We assessed: (a) augmentation index (Aix) and pulse wave velocity (PWV); (b) perfusion boundary region (PBR) of sublingual microvasculature (range:5-25 μm), an index of the endothelial glycocalyx thickness, using Sideview, Darkfield imaging; (c) the exhaled CO; and (d) the malondialdehyde (MDA) and protein carbonyls (PC) plasma levels, as markers of oxidative stress, at baseline and after 3 and 12 months. After 3 months of treatment, CO, MDA, PC and Aix were decreased in all subjects (median CO: 25 vs. 6 ppm, MDA: 0.81 vs. 0.63 nmol/L, PC: 0.102, vs. 0.093 nmol/mg protein, Aix: 13% vs. 9%, p smoking (n = 84 out of 188), while the above markers and PWV deteriorated in relapsed smokers (p smoking cessation program using varenicline or NRT for 3 months resulted in a decrease of CO, oxidative stress, arterial stiffness and restored endothelial glycocalyx. These effects were more evident after varenicline treatment, likely because of a greater CO reduction, and were maintained after 1 year only in subjects who abstained from smoking. Copyright © 2017 Elsevier B.V. All rights reserved.

Disposition scenarios and safeguardability of fissile materials under START Treaty

International Nuclear Information System (INIS)

Pillay, K.K.S.

1993-01-01

Under the Strategic Arms Reduction Treaty (START-I) signed in 1991 and the Lisbon Protocol of 1992, a large inventory of fissile materials will be removed from the weapons fuel cycles of the United States and the Former Soviet Union (FSU). The Lisbon Protocol calls for Ukraine, Kazakstan, and Byelarus to become nonnuclear members of the treaty and for Russia to assume the responsibility of the treaty as a nuclear weapons state. In addition, the START-II Treaty, which was signed in 1993 by the United States and Russia, further reduces deployed nuclear warheads and adds to the inventory of excess special nuclear materials (SNM). Because storage of in-tact warheads has the potential for a open-quotes breakout,close quotes it would be desirable to dismantle the warheads and properly dispose of the SNMs under appropriate safeguards to prevent their reentry into the weapons fuel cycle. The SNM recovered from dismantled warheads can be disposed of in several ways, and the final choices may be up to the country having the title to the SNM. Current plans are to store them indefinitely, leaving serious safeguards concerns. Recognizing that the underlying objective of these treaties is to prevent the fissile materials from reentering the weapons fuel cycle, it is necessary to establish a verifiable disposal scheme that includes safeguards requirements. This paper identifies some realistic scenarios for the disposal of SNM from the weapons fuel cycle and examines the safeguardability of those scenarios

Long-period maintenance program of JRR-3M

International Nuclear Information System (INIS)

Murayama, Yoji; Onozaki, Michio; Kakefuda, Kazuhiro

1999-01-01

The JRR-3M is a swimming pool type research reactor with maximum thermal output of 20 MW, classed in a large-scale research reactor and composed of numerous facilities. An operation cycle consists of 4 weeks of continuously reactor operation and 1 week of shutdown work such as fuel exchange and irradiation sample handling. The temporary and small-scale maintenance is also carried out during the shutdown period. Systematic maintenance period through a year usually follows 2 stages. The former stage of about 4 weeks is prepared to maintain the general facilities related to the overall reactor system such as computer system. The latter stage of about 9 weeks is prepared to maintain the other individual facilities such as cooling facilities and control facilities that are to be inspected by the regulatory body. Since preventive maintenance is required in order to achieve an improvement of safety, reliability and availability throughout the life cycle of the reactor, a long-period maintenance program should be prepared properly in consideration of an ageing degradation of the facilities. The long-period maintenance program of JRR-3M, which determines not only the replacement frequency but also the maintenance frequency of the facilities, is made on the basis of an ageing degradation of the facilities, irradiation effects of the materials, recommendations from the manufacturer and JRR-3M maintenance records. The replacement frequency recommended by the manufacturer is examined from the viewpoint of the safety significance of the facilities and availability of the components. The program is arranged so that it may not concentrate the replacement of the facilities in the specific fiscal year and smooth the budget and maintenance period throughout the life cycle of the reactor. There have been two unanticipated failures of the facilities, which required rearranging the program. (author)

Replacement and inspection policies for products with random life cycle

International Nuclear Information System (INIS)

Yun, Won Young; Nakagawa, Toshio

2010-01-01

In this paper, we consider maintenance policies for products in which the economical life cycle of products is a random variable. First, we study a periodic replacement policy with minimal repair. The system is minimally repaired at failure and is replaced by new one at age T (periodic replacement policy with minimal repair of Barlow and Hunter). The expected present value of total maintenance cost of products with random life cycle is obtained and the optimal replacement interval minimizing the cost is found. Second, we consider an inspection policy for products with random life cycle to detect the system failure. The expected total cost is obtained and the optimal inspection interval is found. Numerical examples are also included.

Fluorescent Lamp Replacement Study

Science.gov (United States)

2017-07-01

not be cited for purposes of advertisement. DISPOSITION INSTRUCTIONS: Destroy this document when no longer needed. Do not return to the... recycling , and can be disposed safely in a landfill. (2) LEDs offer reduced maintenance costs and fewer bulb replacements, significantly reducing... recycling . Several fixtures, ballasts and energy efficient fluorescent bulbs that were determined to be in pristine condition were returned to ATC

78 FR 13549 - Special Supplemental Nutrition Program for Women, Infants and Children (WIC): Implementation of...

Science.gov (United States)

2013-02-28

... strategic plan outlining its technology vision to modernize and/or replace antiquated clinic certification... Program benefits. 3. Providing the WIC Program with data useful to improve program management and integrity. This includes data on the type, brand and cost of each food item so State agencies can better...

Application of capital replacement models with finite planning horizons

NARCIS (Netherlands)

Scarf, P.A.; Christer, A.H.

1997-01-01

Capital replacement models with finite planning horizons can be used to model replacement policies in complex operational contexts. They may also be used to investigate the cost consequences of technological change. This paper reviews the application of these models in various such contexts. We also

Implementation of a tobacco-free workplace program at a local mental health authority.

Science.gov (United States)

Correa-Fernández, Virmarie; Wilson, William T; Shedrick, Deborah A; Kyburz, Bryce; L Samaha, Hannah; Stacey, Timothy; Williams, Teresa; Lam, Cho Y; Reitzel, Lorraine R

2017-06-01

Tobacco-free workplace policies that incorporate evidence-based practices can increase the reach and effectiveness of tobacco dependence treatment among underserved populations but may be underutilized due to limited knowledge about implementation processes. This paper describes the implementation of a comprehensive tobacco-free workplace program at a behavioral healthcare community center in Texas. The center participated in a tobacco-free workplace program implementation project that provided guidance and resources and allowed center autonomy in implementation. Six employee-based subcommittees guided implementation of program components including consumer and staff surveys, policy development, signage, tobacco use assessments, communication, and nicotine replacement distribution. Timeline development, successes, challenges, lessons learned, and sustainability initiatives are delineated. Concerns about the tobacco-free workplace policy from the center's staff and consumers were gradually replaced by strong support for the initiative. Program success was enabled by consistent support from the center's leadership, publicity of program efforts, and educational campaigns. The center surpassed the program expectations when it adopted a tobacco-free hiring policy, which was not an initial program goal. This center's path to a tobacco-free workplace provides an implementation and sustainability model for other behavioral health community centers and other organizations to become tobacco free.

Replacement Power Facility site selection report

Energy Technology Data Exchange (ETDEWEB)

Wike, L.D.; Toole, G.L.; Specht, W.L.

1992-06-01

The Department of Energy (DOE) has proposed the construction and operation of a Replacement Power Facility (RPF) for supplementing and replacing existing sources of steam and possibly electricity at the Savannah River Site (SRS). DOE is preparing an Environmental Impact Statement (EIS) for this project As part of the impact analysis of the proposed action, the EIS will include a detailed description of the environment where the RPF will be constructed. This description must be specific to the recommended site at SRS, which contains more than 300 square miles of land including streams, lakes, impoundments, wetlands, and upland areas. A formal site-selection process was designed and implemented to identify the preferred RPF site.

Rapid replacement/construction of bridges.

Science.gov (United States)

2012-11-01

Bridges are a key element of the transportation system because they control system capacity and are normally built at : the highest cost to the system. Once a bridge reaches its useful design service life, it needs to be replaced or : reconstructed i...

QUALITY OF LIFE, COUNSELLING AND HORMONE REPLACEMENT THERAPY

Directory of Open Access Journals (Sweden)

Nena Kopčavar Guček

2008-12-01