Theoretical Relevance of Neuropsychological Data for Connectionist Modelling
Mauricio Iza
2011-05-01
Full Text Available The symbolic information-processing paradigm in cognitive psychology has met a growing challenge from neural network models over the past two decades. While neuropsychological
evidence has been of great utility to theories concerned with information processing, the real question is, whether the less rigid connectionist models provide valid, or enough, information
concerning complex cognitive structures. In this work, we will discuss the theoretical implications that neuropsychological data posits for modelling cognitive systems.
Evans, Richard I
2003-01-01
For the past several years the author and his colleagues have explored the area of how social psychological constructs and theoretical models can be applied to the prevention of health threatening behaviors in adolescents. In examining the need for the development of gambling prevention programs for adolescents, it might be of value to consider the application of such constructs and theoretical models as a foundation to the development of prevention programs in this emerging problem behavior among adolescents. In order to provide perspective to the reader, the present paper reviews the history of various psychosocial models and constructs generic to programs directed at prevention of substance abuse in adolescents. A brief history of some of these models, possibly most applicable to gambling prevention programs, are presented. Social inoculation, reasoned action, planned behavior, and problem behavior theory, are among those discussed. Some deficits of these models, are also articulated. How such models may have relevance to developing programs for prevention of problem gambling in adolescents is also discussed. However, the inherent differences between gambling and more directly health threatening behaviors such as substance abuse must, of course, be seriously considered in utilizing such models. Most current gambling prevention programs have seldom been guided by theoretical models. Developers of gambling prevention programs should consider theoretical foundations, particularly since such foundations not only provide a guide for programs, but may become critical tools in evaluating their effectiveness.
Edmund O. Amoakoh
2017-03-01
Full Text Available Relationship marketing (RM concept seems to be best understood and embraced more by big business, while amongst myriad of small businesses it seems less prominent. This paper explores the need for RM as a determinant to hair salon’s competitiveness and growth. Hair industry in SA is declared a multi-billion dollar industry, their stagnation prompted this study. This paper contends that relationship building with customers has a profound effect on the inclination of a customer to return to the business. With the key variables of the relationship marketing model as the main determinants are namely service quality, customer satisfaction and customer retention. Increased practice of RM within this industry will enable owners to embrace entrepreneurial activities imperative for competitiveness, value creation and sustainability.
Goal relevance as a quantitative model of human task relevance.
Tanner, James; Itti, Laurent
2017-03-01
The concept of relevance is used ubiquitously in everyday life. However, a general quantitative definition of relevance has been lacking, especially as pertains to quantifying the relevance of sensory observations to one's goals. We propose a theoretical definition for the information value of data observations with respect to a goal, which we call "goal relevance." We consider the probability distribution of an agent's subjective beliefs over how a goal can be achieved. When new data are observed, its goal relevance is measured as the Kullback-Leibler divergence between belief distributions before and after the observation. Theoretical predictions about the relevance of different obstacles in simulated environments agreed with the majority response of 38 human participants in 83.5% of trials, beating multiple machine-learning models. Our new definition of goal relevance is general, quantitative, explicit, and allows one to put a number onto the previously elusive notion of relevance of observations to a goal. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
Theoretical Models of Generalized Quasispecies.
Wagner, Nathaniel; Atsmon-Raz, Yoav; Ashkenasy, Gonen
2016-01-01
Theoretical modeling of quasispecies has progressed in several directions. In this chapter, we review the works of Emmanuel Tannenbaum, who, together with Eugene Shakhnovich at Harvard University and later with colleagues and students at Ben-Gurion University in Beersheva, implemented one of the more useful approaches, by progressively setting up various formulations for the quasispecies model and solving them analytically. Our review will focus on these papers that have explored new models, assumed the relevant mathematical approximations, and proceeded to analytically solve for the steady-state solutions and run stochastic simulations . When applicable, these models were related to real-life problems and situations, including changing environments, presence of chemical mutagens, evolution of cancer and tumor cells , mutations in Escherichia coli, stem cells , chromosomal instability (CIN), propagation of antibiotic drug resistance , dynamics of bacteria with plasmids , DNA proofreading mechanisms, and more.
Theoretical research relevant to medium energy upgrades and experiments
Goldman, T.; Benesh, C.; Carlson, J. [and others
1996-07-01
This is the final report of a three-year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). This work provides theoretical research results for sources of pions, neutrons, neutrinos and heavy ions. The authors have undertaken specific calculations in neutrino-nucleus scattering and to analyze constraints on exotic decays relevant to the study of neutrino oscillations. They have also performed calculations regarding neutrino cosmology and astrophysics relevant to the experimental study of neutrino masses. They analyzed the constraints of data on T-violation in neutron decay and the nucleon-nucleon (NN) interaction which will be important for the understanding of experiments with cold and ultra-cold neutrons. They completed several specific calculations which were essential to predict (pion, kaon) hypernuclear production and pion-induced reactions studying baryonic resonances. They also calculated the nuclear spectroscopy of nuclei far from stability that can be studied experimentally.
Theoretical model of ``fuzz'' growth
Krasheninnikov, Sergei; Smirnov, Roman
2012-10-01
Recent more detailed experiments on tungsten irradiation with low energy helium plasma, relevant to the near-wall plasma conditions in magnetic fusion reactor like ITER, demonstrated (e.g. see Ref. 1) a very dramatic change in both surface morphology and near surface material structure of the samples. In particular, it was shown that a long (mm-scale) and thin (nm-scale) fiber-like structures filled with nano-bubbles, so-called ``fuzz,'' start to grow. In this work theoretical model of ``fuzz'' growth [2] describing the main features observed in experiments is presented. This model, based on the assumption of enhancement of creep of tungsten containing significant fraction of helium atoms and clusters. The results of the MD simulations [3] support this idea and demonstrate a strong reduction of the yield strength for all temperature range. They also show that the ``flow'' of tungsten strongly facilitates coagulation of helium clusters and the formation of nano-bubbles.[4pt] [1] M. J. Baldwin, et al., J. Nucl. Mater. 390-391 (2009) 885;[0pt] [2] S. I. Krasheninnikov, Physica Scripta T145 (2011) 014040;[0pt] [3] R. D. Smirnov and S. I. Krasheninnikov, submitted to J. Nucl. Materials.
Theoretical Views, Relevant Models and Prospects in Emotion Regulation%情绪调节的理论观点、相关模型及其展望
张文海; 卢家楣
2012-01-01
Emotion regulation, which belongs to an important aspect of social development during early childhood and adolescence, is a critical mechanism of mental development for normal and abnormal individuals. Now emotion regulation takes on an interdisciplinary trend and has recently attracted widespread attention of many researchers. However, its definition and its neural mechanism are still unclear. The review includes three parts. In the first part, we reviewed two typical views in the field of emotion regulation, the one-factor and the two-factor approaches. The one-factor approach proposes that emotion generation and emotion regulation are two distinct processes ; researchers first induce an emotion and then study the process of emotion regulation. By contrast, the two-factor approach proposes that emotion generation and emotion regulation are an inseparable phenomenon; emotion regulation occurs throughout the emotion-generation processe. In the second part, we focused on Gross's process model of emotion regulation, and stressed Ochsner's cognitive control model of emotion from neuroscience. In Gross's process model, individual difference emerges in five sub-processes: contextual selection, contextual modification, attention deployment, cognitive change, and response modulation ; these processes form a continuum from effortful, controllable, and deliberate regulation to effortless, automatic, and unconscious regulation. In Ochsner's cognitive control model, emotions originate from the interaction of multiple evaluation systems, bottom-up and/or top-down, including description-based appraisal system and outcome-based appraisal system. The neural correlates refer to the response evaluation system (e. g. , amygdale, nucleus accumbens, insula) and the regulation system (e. g. , prefrontal cortex, anterior cingulate cortex, orbitofrontal cortex). In the third part, future research should apply observation and experience sampling to carry out longitudinal studies, make
Theoretical models for supernovae
Woosley, S.E.; Weaver, T.A.
1981-09-21
The results of recent numerical simulations of supernova explosions are presented and a variety of topics discussed. Particular emphasis is given to (i) the nucleosynthesis expected from intermediate mass (10sub solar less than or equal to M less than or equal to 100 Msub solar) Type II supernovae and detonating white dwarf models for Type I supernovae, (ii) a realistic estimate of the ..gamma..-line fluxes expected from this nucleosynthesis, (iii) the continued evolution, in one and two dimensions, of intermediate mass stars wherein iron core collapse does not lead to a strong, mass-ejecting shock wave, and (iv) the evolution and explosion of vary massive stars (M greater than or equal to 100 Msub solar of both Population I and III. In one dimension, nuclear burning following a failed core bounce does not appear likely to lead to a supernova explosion although, in two dimensions, a combination of rotation and nuclear burning may do so. Near solar proportions of elements from neon to calcium and very brilliant optical displays may be created by hypernovae, the explosions of stars in the mass range 100 M/sub solar/ to 300 M/sub solar/. Above approx. 300 M/sub solar/ a black hole is created by stellar collapse following carbon ignition. Still more massive stars may be copious producers of /sup 4/He and /sup 14/N prior to their collapse on the pair instability.
Social Impact, a Theoretical Model
Jenny Onyx
2014-01-01
Full Text Available This paper constructs a theoretical model of social impact as it applies to civil society organisations. It does so by drawing on the recent literature on the topic as well as recently completed empirical studies. First, the relationship between impact and evaluation is examined. This is followed by an exploration of the capitals, notably social, human, and cultural capital and their interrelationships, as a theoretical base for the explication of social impact. A formal model of social impact is then identified together with a set of basic principles that may be said to define social impact. Finally the implications of the model are discussed for social policy and organisational management.
Treatment of Cultural Default in Literary Translation from the Relevance-Theoretic Perspective
胡敏燕
2016-01-01
The present paper intends to argue that treatment of cultural default in literary translation can be accounted for within the relevance theory. An account of relevance theory is presented. Detailed analysis of some representative examples of transla-tion within the relevance-theoretic framework is made. The notions in Relevance Theory can effectively account for the opera-tion of different translation methods and techniques when tackling the cultural default. The purpose of using various translation skills is to obtain the optimal relevance between cognitive context in target readers'minds and communication intention of the original author.
Modelling Complex Relevance Spaces with Copulas
C. Eickhoff (Carsten); A.P. de Vries (Arjen)
2014-01-01
htmlabstractModern relevance models consider a wide range of criteria in order to identify those documents that are expected to satisfy the user's information need. With growing dimensionality of the underlying relevance spaces the need for sophisticated score combination and estimation schemes
Passage relevance models for genomics search
Frieder Ophir
2009-03-01
Full Text Available Abstract We present a passage relevance model for integrating syntactic and semantic evidence of biomedical concepts and topics using a probabilistic graphical model. Component models of topics, concepts, terms, and document are represented as potential functions within a Markov Random Field. The probability of a passage being relevant to a biologist's information need is represented as the joint distribution across all potential functions. Relevance model feedback of top ranked passages is used to improve distributional estimates of query concepts and topics in context, and a dimensional indexing strategy is used for efficient aggregation of concept and term statistics. By integrating multiple sources of evidence including dependencies between topics, concepts, and terms, we seek to improve genomics literature passage retrieval precision. Using this model, we are able to demonstrate statistically significant improvements in retrieval precision using a large genomics literature corpus.
A Set Theoretical Approach to Maturity Models
Lasrado, Lester; Vatrapu, Ravi; Andersen, Kim Normann
2016-01-01
Maturity Model research in IS has been criticized for the lack of theoretical grounding, methodological rigor, empirical validations, and ignorance of multiple and non-linear paths to maturity. To address these criticisms, this paper proposes a novel set-theoretical approach to maturity models ch...
Unified Hybrid Network Theoretical Model Trilogy
无
2011-01-01
The first of the unified hybrid network theoretical model trilogy (UHNTF) is the harmonious unification hybrid preferential model (HUHPM), seen in the inner loop of Fig. 1, the unified hybrid ratio is defined.
Theoretical Models for Orthogonal Cutting
De Chiffre, Leonardo
This review of simple models for orthogonal cutting was extracted from: “L. De Chiffre: Metal Cutting Mechanics and Applications, D.Sc. Thesis, Technical University of Denmark, 1990.”......This review of simple models for orthogonal cutting was extracted from: “L. De Chiffre: Metal Cutting Mechanics and Applications, D.Sc. Thesis, Technical University of Denmark, 1990.”...
Theoretical Models for Orthogonal Cutting
De Chiffre, Leonardo
This review of simple models for orthogonal cutting was extracted from: “L. De Chiffre: Metal Cutting Mechanics and Applications, D.Sc. Thesis, Technical University of Denmark, 1990.”......This review of simple models for orthogonal cutting was extracted from: “L. De Chiffre: Metal Cutting Mechanics and Applications, D.Sc. Thesis, Technical University of Denmark, 1990.”...
Theoretical model of digital archives
Alenka Kavčič-Čolić
2004-01-01
Full Text Available There are certain conditions that national organizations should fulfill to became trusted digital repositories. Among other things, their deposit system should be in compliance with the reference model for an Open Archival Information System (OAIS. In this paper the model OAIS is presented as well as some important international experiences regarding its implementation. The joint project of the National and University Library and The Jozef Stefan Institute, which is aimed at developing such a digital archive based on OAIS, is also mentioned.
Critical review of problem solving processes traditional theoretical models
Botía Sanabria, María Lucero; Universidad Antonio Nariño, Bogotá, Colombia; Orozco Pulido, Luis Humberto; Universidad Antonio Nariño, Bogotá, Colombia
2015-01-01
This paper presents a brief analysis of most known problem solving theoretical models realized using epistemological categories such as observer position, object of study, methods and procedures, and descriptive or explicative scope. The review showed linear and cyclical models, the need to recognize method's limitations to generalizing, the relevance of expliciting observer position, and a diffuse delimitation of the object problem solving as a cognitive process. An integrative and molar the...
Catalyst Deactivation: Control Relevance of Model Assumptions
Bernt Lie
2000-10-01
Full Text Available Two principles for describing catalyst deactivation are discussed, one based on the deactivation mechanism, the other based on the activity and catalyst age distribution. When the model is based upon activity decay, it is common to use a mean activity developed from the steady-state residence time distribution. We compare control-relevant properties of such an approach with those of a model based upon the deactivation mechanism. Using a continuous stirred tank reactor as an example, we show that the mechanistic approach and the population balance approach lead to identical models. However, common additional assumptions used for activity-based models lead to model properties that may deviate considerably from the correct one.
Bordás, Barna; Bélai, Iván; Koomíves, Tamás
2011-04-13
The uptake of persistent organic pollutants (POPs) from soil by plants allows the development of phytoremediation protocols to rehabilitate contaminated areas. The use of diverse theoretical descriptors has been reported in the literature for developing quantitative structure-activity relationship (QSAR) models for predicting the bioconcentration factors (BCFs) of POPs in different plants. In this paper an evaluation is given on the molecular properties of POPs in terms of theoretical molecular descriptors that are relevant to the uptake and accumulation of these persistent pollutants from soil by two zucchini varieties. Statistically significant and predictive linear regression models have been developed for the BCF values of 20 polychlorinated dibenzo-p-dioxins/dibenzofurans and 14 polyhalogenated biphenyls in two zucchini varieties based on retrospective data. The relevant parameters have been selected from a set of 1660 DRAGON, 150 VolSurf, and 11 quantum chemical descriptors. The two most significant regression models, containing VolSurf, DRAGON GETAWAY, and quantum chemical descriptors, displayed the following statistical parameters: (eq 3) n = 27, R(2) = 0.940, q(2) = 0.922, SE = 0.155, F = 392.1; (eq 4) n = 27, R(2) = 0.921, q(2) = 0.898, SE = 0.161, F = 140.4. Predictive capabilities of the equations have been validated by using external validation sets. The QSAR models proposed might contribute to the development of viable soil remediation strategies.
Theoretical modeling of electromagnetically imploded plasma liners
Roderick, N.F.; Kohn, B.J.; McCullough, W.F.; Beason, C.W.; Lupo, J.A.; Letterio, J.D. (Air Force Weapons Lab., Kirtland AFB, NM (USA)); Kloc, D.A. (Air Force Academy, CO (USA)); Hussey, T.W. (Sandia National Labs., Albuquerque, NM (USA))
1983-05-01
The generation of high-energy-density plasmas by the electromagnetic implosion of cylindrical foils is explored analytically and through numerical simulation. Theoretical investigations have been performed for a variety of foil initial conditions for both capacitive and inductive pulsed power systems. The development of the theoretical modeling techniques is presented, covering both circuit models and plasma load models. Results from a series of configurations are given, showing the development of modelling techniques used to study the dynamics of the plasma implosion process and the role of instabilities. Interaction between analytic techniques and detailed numerical simulation has led to improvement in all theoretical modeling techniques presently used to study the implosion process. Comparisons of implosion times, shell structure, instability growth rates, and thermalization times have shown good agreement between analytic/heuristic techniques and more detailed two dimensional magnetohydrodynamic simulations. These in turn have provided excellent agreement with experimental results for both capacitor and inductor pulse power systems.
The relevance of postcolonial theoretical perspectives to research in Aboriginal health.
Browne, Annette J; Smye, Victoria L; Varcoe, Colleen
2005-12-01
The authors critically examine the relevance of postcolonial theoretical perspectives to nursing research in the area of Aboriginal health. They discuss key theoretical underpinnings of postcolonial theory, citing differences and commonalities in postcolonial theory, postcolonial indigenous thinking, and other forms of critical theory. Drawing on insights from Aboriginal scholars, they critique the relevance of postcolonial discourses to issues of concern to Aboriginal peoples, and the potential limitations of those discourses. They then consider the implications of conducting research that is informed by postcolonial perspectives. They argue that postcolonial perspectives provide direction for research with Aboriginal communities in 4 interrelated ways. These are focused on (a) issues of partnership and "voice" in the research process, (b) a commitment to engaging in praxis-oriented inquiry, (c) understanding how continuities from the past shape the present context of health and health care, and (d) the colonizing potential of research. The authors draw attention to the concept of cultural safety as an instrument for incorporating postcolonial perspectives into the realm of nursing. To illustrate applications of postcolonial theory, they give examples from recent research conducted in partnership with Aboriginal communities. Although postcolonial theories are relatively new in nursing discourses, they provide a powerful analytical framework for considering the legacy of the colonial past and the neocolonial present as the context in which health care is delivered.
Mpofu, Vongai; Otulaja, Femi S.; Mushayikwa, Emmanuel
2014-03-01
A theoretical framework is an important component of a research study. It grounds the study and guides the methodological design. It also forms a reference point for the interpretation of the research findings. This paper conceptually examines the process of constructing a multi-focal theoretical lens for guiding studies that aim to accommodate local culture in science classrooms. A multi-focal approach is adopted because the integration of indigenous knowledge and modern classroom science is complex. The central argument in this paper is that a multi-focal lens accommodates the multifaceted nature of integrating indigenous knowledge and western oriented classroom science. The objective of the paper, therefore, is to construct a theoretical framework that can be used to guide and inform the integration of indigenous knowledge and western science at classroom science level. The traditional plant healing form of indigenous knowledge is used as a case study. The paper is important for raising the complexities, tensions and dilemmas inherent in the design and implementation of indigenous knowledge-science integrated curricula. An understanding of the issues raised will pave the way towards achieving culturally relevant classroom science.
Modeling business processes: theoretical and practical aspects
V.V. Dubininа
2015-06-01
Full Text Available The essence of process-oriented enterprise management has been examined in the article. The content and types of information technology have been analyzed in the article, due to the complexity and differentiation of existing methods, as well as the specificity of language, terminology of the enterprise business processes modeling. The theoretical aspects of business processes modeling have been reviewed and the modern traditional modeling techniques received practical application in the visualization model of retailers activity have been studied in the article. In the process of theoretical analysis of the modeling methods found that UFO-toolkit method that has been developed by Ukrainian scientists due to it systemology integrated opportunities, is the most suitable for structural and object analysis of retailers business processes. It was designed visualized simulation model of the business process "sales" as is" of retailers using a combination UFO-elements with the aim of the further practical formalization and optimization of a given business process.
Advances in theoretical models of network science
FANG Jin-qing; BI Qiao; LI Yong
2007-01-01
In this review article, we will summarize the main advances in network science investigated by the CIAE Group of Complex Network in this field. Several theoretical models of network science were proposed and their topological and dynamical properties are reviewed and compared with the other models. Our models mainly include a harmonious unifying hybrid preferential model, a large unifying hybrid network model, a quantum interference network, a hexagonal nanowire network, and a small-world network with the same degree. The models above reveal some new phenomena and findings, which are useful for deeply understanding and investigating complex networks and their applications.
A theoretical model of multielectrode DBR lasers
Pan, Xing; Olesen, Henning; Tromborg, Bjarne
1988-01-01
A theoretical model for two- and three-section tunable distributed Bragg reflector (DBR) lasers is presented. The static tuning properties are studied in terms of threshold current, linewidth, oscillation frequency, and output power. Regions of continuous tuning for three-section DBR lasers...
Some Model Theoretic Remarks on Bass Modules
E. Momtahan
2011-09-01
Full Text Available We study Bass modules, Bass rings, and related concepts from a model theoretic point of view. We observe that the class of Bass modules (over a fixed ring is not stable under elementary equivalence. We observe that under which conditions the class of Bass rings are stable under elementary equivalence.
Hybrid quantum teleportation: A theoretical model
Takeda, Shuntaro; Mizuta, Takahiro; Fuwa, Maria; Yoshikawa, Jun-ichi; Yonezawa, Hidehiro; Furusawa, Akira [Department of Applied Physics, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan)
2014-12-04
Hybrid quantum teleportation – continuous-variable teleportation of qubits – is a promising approach for deterministically teleporting photonic qubits. We propose how to implement it with current technology. Our theoretical model shows that faithful qubit transfer can be achieved for this teleportation by choosing an optimal gain for the teleporter’s classical channel.
[Holism in theoretical models of nursing].
Neto, D L; da Nóbrega, M M
1999-01-01
In this bibliographical analysis, we present the classification of nine theoretical nursing models which frame holistic thinking according to the school of thought of Human Needs, Interaction and Outcome. It further describes the definition of holism, health, client and nursing in the holistic conception, with the objective of portraying holism in the theoretical references of nursing: The Ambiental Theory of Nightingale, the Interpersonal Theory of Peplau, the Philosophical Theory of Hall, The Theory of Basics Principals of Henderson, the Theory of Self Care of Orem, the Prescriptive Theory of Wiedenbach, the Theory of Basic Needs of Horta, the Theory of Adaptation of Roy and the Theory of Holism of Levine.
Error Estimates of Theoretical Models: a Guide
Dobaczewski, J; Reinhard, P -G
2014-01-01
This guide offers suggestions/insights on uncertainty quantification of nuclear structure models. We discuss a simple approach to statistical error estimates, strategies to assess systematic errors, and show how to uncover inter-dependencies by correlation analysis. The basic concepts are illustrated through simple examples. By providing theoretical error bars on predicted quantities and using statistical methods to study correlations between observables, theory can significantly enhance the feedback between experiment and nuclear modeling.
Theoretical model of smooth disk operation
Krauze, K.
1985-02-01
Aes a theoretical model is analyzed for coal cutting by disk cutters mounted on a helical cutting drum of a shearer loader. The model is based on the assumption that failure of coal cohesion is caused by crushing and separation of coal grains from a coal face and that coal cutting resistance depends on its contact strength as well as cutting depth and cutting angle. 1 reference.
Modelling in Accounting. Theoretical and Practical Dimensions
Teresa Szot-Gabryś
2010-10-01
Full Text Available Accounting in the theoretical approach is a scientific discipline based on specific paradigms. In the practical aspect, accounting manifests itself through the introduction of a system for measurement of economic quantities which operates in a particular business entity. A characteristic of accounting is its flexibility and ability of adaptation to information needs of information recipients. One of the main currents in the development of accounting theory and practice is to cover by economic measurements areas which have not been hitherto covered by any accounting system (it applies, for example, to small businesses, agricultural farms, human capital, which requires the development of an appropriate theoretical and practical model. The article illustrates the issue of modelling in accounting based on the example of an accounting model developed for small businesses, i.e. economic entities which are not obliged by law to keep accounting records.
Theoretical Model of Steel Continuous Casting Technology
C Gheorghies; I Crudu; C Teletin; C Spanu
2009-01-01
A theoretical model adapted for studying steel continuous casting technology was proposed.The model based on system theory contained input/output,command,and control parameters.The process was divided into five stages,i.e.,tundish,mold,guiding system,guiding-drawing system,and guiding-drawing-soft reduction system.The model can be used to describe the physicoehemical processes,thermal processes,chemical processes,and characteristics of the cast material according to the above-mentioned stages.It can also be applied to other metallurgical technologies and even to other industries (chemistry,food,etc.).
Numerical modelling of corrosion - Theoretical backgrounds -
Warkus, J.; Raupach, M. [ibac, RWTH Aachen (Germany); Gulikers, J. [Ministry of Transport, Rijkswaterstaat, Bouwdienst, Utrecht (Netherlands)
2006-08-15
During recent years research projects with different approaches have been carried out to develop models which are suitable to assess the metal removal rate in case of reinforcement corrosion. Some of them are based on empirical methods and correlate the corrosion rate to parameters like concrete resistivity, temperature and relative humidity. Another type of model is based on a quantification of the ongoing electrochemical processes. In this paper the theoretical backgrounds and mathematical descriptions of reinforcement corrosion with regard to a numerical modelling are presented and discussed. (Abstract Copyright [2006], Wiley Periodicals, Inc.)
Theoretical aspects of spatial-temporal modeling
Matsui, Tomoko
2015-01-01
This book provides a modern introductory tutorial on specialized theoretical aspects of spatial and temporal modeling. The areas covered involve a range of topics which reflect the diversity of this domain of research across a number of quantitative disciplines. For instance, the first chapter provides up-to-date coverage of particle association measures that underpin the theoretical properties of recently developed random set methods in space and time otherwise known as the class of probability hypothesis density framework (PHD filters). The second chapter gives an overview of recent advances in Monte Carlo methods for Bayesian filtering in high-dimensional spaces. In particular, the chapter explains how one may extend classical sequential Monte Carlo methods for filtering and static inference problems to high dimensions and big-data applications. The third chapter presents an overview of generalized families of processes that extend the class of Gaussian process models to heavy-tailed families known as alph...
User's Relevance of PIR System Based on Cloud Models
KANG Hai-yan; FAN Xiao-zhong
2006-01-01
A new method to evaluate fuzzily user's relevance on the basis of cloud models has been proposed.All factors of personalized information retrieval system are taken into account in this method. So using this method for personalized information retrieval (PIR) system can efficiently judge multi-value relevance, such as quite relevant, comparatively relevant, commonly relevant, basically relevant and completely non-relevant,and realize a kind of transform of qualitative concepts and quantity and improve accuracy of relevance judgements in PIR system. Experimental data showed that the method is practical and valid. Evaluation results are more accurate and approach to the fact better.
A theoretical model of metal surface reactions
Shustorovich, E. (Eastman Kodak Co., Rochester, NY); Baetzold, R.C.; Muetterties, E.L.
1983-03-31
Metal surface reactions are modeled with a novel theoretical construct in which periodic trends can be scrutinized. The theoretical model is succinctly presented and a conspectus of periodic trends, based on the model, is explored. Periodic trends are discussed in the contexts of chemisorption bond energies, electron transfer between metal surface and adsorbate, stereochemical features of chemisorption states for closed-shell diatomic and linear X-CN or X-NC molecules, and hydrocarbon reactions. Hydrocarbon C-H bond-breaking processes are analyzed in terms of d-level occupancy, electron transfer, and stereochemistry of intermediates. Conceptually and computationally, the metal surface is characterized as a good electron donor: antibonding molecular orbitals of the adsorbate species appear to be significant contributors to the chemisorption bond and also play a decisive role in bond-breaking processes. No aspect of the model projections is inconsistent with the experimental data although the electronic characterization of some chemisorption states are counter to commonly held perceptions.
A Theoretical Model of Water and Trade
Dang, Q.; Konar, M.; Reimer, J.; Di Baldassarre, G.; Lin, X.; Zeng, R.
2015-12-01
Water is an essential factor of agricultural production. Agriculture, in turn, is globalized through the trade of food commodities. In this paper, we develop a theoretical model of a small open economy that explicitly incorporates water resources. The model emphasizes three tradeoffs involving water decision-making that are important yet not always considered within the existing literature. One tradeoff focuses on competition for water among different sectors when there is a shock to one of the sectors only, such as trade liberalization and consequent higher demand for the product. A second tradeoff concerns the possibility that there may or may not be substitutes for water, such as increased use of sophisticated irrigation technology as a means to increase crop output in the absence of higher water availability. A third tradeoff explores the possibility that the rest of the world can be a source of supply or demand for a country's water-using products. A number of propositions are proven. For example, while trade liberalization tends to increase water use, increased pressure on water supplies can be moderated by way of a tax that is derivable with observable economic phenomena. Another example is that increased riskiness of water availability tends to cause water users to use less water than would be the case under profit maximization. These theoretical model results generate hypotheses that can be tested empirically in future work.
Theoretical Models of the Galactic Bulge
Shen, Juntai; Li, Zhao-Yu
Near infrared images from the COBE satellite presented the first clear evidence that our Milky Way galaxy contains a boxy shaped bulge. Recent years have witnessed a gradual paradigm shift in the formation and evolution of the Galactic bulge. Bulges were commonly believed to form in the dynamical violence of galaxy mergers. However, it has become increasingly clear that the main body of the Milky Way bulge is not a classical bulge made by previous major mergers, instead it appears to be a bar seen somewhat end-on. The Milky Way bar can form naturally from a precursor disc and thicken vertically by the internal firehose/buckling instability, giving rise to the boxy appearance. This picture is supported by many lines of evidence, including the asymmetric parallelogram shape, the strong cylindrical rotation (i.e., nearly constant rotation regardless of the height above the disc plane), the existence of an intriguing X-shaped structure in the bulge, and perhaps the metallicity gradients. We review the major theoretical models and techniques to understand the Milky Way bulge. Despite the progresses in recent theoretical attempts, a complete bulge formation model that explains the full kinematics and metallicity distribution is still not fully understood. Upcoming large surveys are expected to shed new light on the formation history of the Galactic bulge.
Mpofu, Vongai; Otulaja, Femi S.; Mushayikwa, Emmanuel
2014-01-01
A theoretical framework is an important component of a research study. It grounds the study and guides the methodological design. It also forms a reference point for the interpretation of the research findings. This paper conceptually examines the process of constructing a multi-focal theoretical lens for guiding studies that aim to accommodate…
Mpofu, Vongai; Otulaja, Femi S.; Mushayikwa, Emmanuel
2014-01-01
A theoretical framework is an important component of a research study. It grounds the study and guides the methodological design. It also forms a reference point for the interpretation of the research findings. This paper conceptually examines the process of constructing a multi-focal theoretical lens for guiding studies that aim to accommodate…
Implementing Relevance Feedback in the Bayesian Network Retrieval Model.
de Campos, Luis M.; Fernandez-Luna, Juan M.; Huete, Juan F.
2003-01-01
Discussion of relevance feedback in information retrieval focuses on a proposal for the Bayesian Network Retrieval Model. Bases the proposal on the propagation of partial evidences in the Bayesian network, representing new information obtained from the user's relevance judgments to compute the posterior relevance probabilities of the documents…
Electron microscopy and theoretical modeling of cochleates.
Nagarsekar, Kalpa; Ashtikar, Mukul; Thamm, Jana; Steiniger, Frank; Schacher, Felix; Fahr, Alfred; May, Sylvio
2014-11-11
Cochleates are self-assembled cylindrical condensates that consist of large rolled-up lipid bilayer sheets and represent a novel platform for oral and systemic delivery of therapeutically active medicinal agents. With few preceding investigations, the physical basis of cochleate formation has remained largely unexplored. We address the structure and stability of cochleates in a combined experimental/theoretical approach. Employing different electron microscopy methods, we provide evidence for cochleates consisting of phosphatidylserine and calcium to be hollow tubelike structures with a well-defined constant lamellar repeat distance and statistically varying inner and outer radii. To rationalize the relation between inner and outer radii, we propose a theoretical model. Based on the minimization of a phenomenological free energy expression containing a bending, adhesion, and frustration contribution, we predict the optimal tube dimensions of a cochleate and estimate ratios of material constants for cochleates consisting of phosphatidylserines with varied hydrocarbon chain structures. Knowing and understanding these ratios will ultimately benefit the successful formulation of cochleates for drug delivery applications.
Theoretical studies of oxides relevant to the combustion of fossil fuels
Hicks, Jason Michael
: adsorption isotherms, Gibbs free energy, enthalpy, entropy and desorption free energy. It was found that, when the maximum loading was compared to the regeneration costs, IRMOF-10 had the best performance, followed by IRMOF-8 then IRMOF-1. During the combustion of coal, not only is CO2 produced, but also the trace elements of arsenic and selenium escape into the environment though this process. Both arsenic and selenium are known to have a harmful effects on the environment and human health. Arsenic is also known to poison the catalytic converter used in selective catalytic reduction of NOx . These trace elements have been found on fly ash or in the hot flue gases released into the atmosphere. In flue gases they most often exist as oxides. There have been many experimental and a few theoretical studies on the monomeric oxides, AsOx and SeOx, where x = 1, 2, or 3. However, little is known concerning the corresponding dimeric oxides, As2Ox and Se2Ox, where x = 3 or 5, though these compounds are expected from their similarities to nitrogen and sulfur chemistry, respectively. From an experimental perspective, they are very challenging to study due to the high temperatures, complex environments and low concentrations needed for a direct study of the form and structures of the dimeric oxides. From a theoretical perspective, they can be challenging to study due to their multireference character and the need for both dynamic and non-dynamic electron correlation due to bonds forming and breaking during isomerization. However, high level multireference ab initio methods which account for both dynamic and non-dynamic electron correlation can be used. In the work contained in this thesis, GVVPT2 and CR-CC(2,3) were used to study the relative stabilities of all relevant isomers and transition states of As2Ox and Se2Ox. The structures used where generated through DFT using the B3LYP functional. Not only were plausible stationary points located for all species, it was further confirmed
Theoretical model of a photoelectrochemical solar cell
Chandra, S.; Singh, S.L.; Khare, N.
1986-03-01
A Schottky barrier theoretical model for explaining the J-V characteristic of a photoelectrochemical solar cell (PESC) has been developed considering the effect of dark current, space-charge recombination, surface states, and detailed charge transfer kinetics at the interface. Both isoenergetic charge transfer and inelastic charge transfers (via surface states) at the interface have been considered and their relative importance are discussed. The theory has been applied to explain the (a) J-V characteristic for n-GaAs/SeS , SeS 2 junction and (b) Fermi-level pinning observed in GaAs PESC. The inelastic charge transfer via surfaces states has been shown to play an important role in deciding these characteristics.
Engel's biopsychosocial model is still relevant today.
Adler, Rolf H
2009-12-01
In 1977, Engel published the seminal paper, "The Need for a New Medical Model: A Challenge for Biomedicine" [Science 196 (1977) 129-136]. He featured a biopsychosocial (BPS) model based on systems theory and on the hierarchical organization of organisms. In this essay, the model is extended by the introduction of semiotics and constructivism. Semiotics provides the language which allows to describe the relationships between the individual and his environment. Constructivism explains how an organism perceives his environment. The impact of the BPS model on research, medical education, and application in the practice of medicine is discussed.
Natasa Milivojevic
2016-06-01
Full Text Available The paper addresses the question of what semantic properties lexicalized in verbs determine their syntactic behavior in intransitive motion events and in resultative constructions in English and Serbian. Special attention is devoted to English and Serbian verbs of emission (specifically verbs of sound emission and partly also verbs of light, smell and substance emission regarding their potential to surface as main verbs in these constructions and to combine with directional phrases within specific morphosyntactic templates (unaccusatives and unergatives. The presented research promotes a theoretical view according to which the established syntactic patterns can be applied across the whole class of verbs of emission to express a full er range of atypical verb meanings in motion events. Theoretical conclusions of the research are also relevant for a wider theoretical description of motion events and resultatives in a cross - linguistic perspective. The paper puts forth additional implica tions regarding the projectionalist approach to semantic verb classes against the theoretical framework of Beth Levin (1993. Finally, the paper considers the relevant points of structurally realized similarities via relevant constructional templates in En glish and in Serbian, as well as some important points of morphosyntactic divergence between the two languages. The conclusions presented aim at a more comprehensive contrastive language typology based on language “framing” parameters.
Relevant phylogenetic invariants of evolutionary models
Casanellas, Marta
2009-01-01
Recently there have been several attempts to provide a whole set of generators of the ideal of the algebraic variety associated to a phylogenetic tree evolving under an algebraic model. These algebraic varieties have been proven to be useful in phylogenetics. In this paper we prove that, for phylogenetic reconstruction purposes, it is enough to consider generators coming from the edges of the tree, the so-called edge invariants. This is the algebraic analogous to Buneman's Splits Equivalence Theorem. The interest of this result relies on its potential applications in phylogenetics for the widely used evolutionary models such as Jukes-Cantor, Kimura 2 and 3 parameters, and General Markov models.
Mathematical Properties Relevant to Geomagnetic Field Modeling
Sabaka, Terence J.; Hulot, Gauthier; Olsen, Nils
2010-01-01
properties of those spatial mathematical representations are also discussed, especially in view of providing a formal justification for the fact that geomagnetic field models can indeed be constructed from ground-based and satellite-born observations, provided those reasonably approximate the ideal......Geomagnetic field modeling consists in converting large numbers of magnetic observations into a linear combination of elementary mathematical functions that best describes those observations.The set of numerical coefficients defining this linear combination is then what one refers...... be directly measured. In this chapter, the mathematical foundation of global (as opposed to regional) geomagnetic field modeling is reviewed, and the spatial modeling of the field in spherical coordinates is focussed. Time can be dealt with as an independent variable and is not explicitly considered...
Mathematical Properties Relevant to Geomagnetic Field Modeling
Sabaka, Terence J.; Hulot, Gauthier; Olsen, Nils
2014-01-01
properties of those spatial mathematical representations are also discussed, especially in view of providing a formal justification for the fact that geomagnetic field models can indeed be constructed from ground-based and satellite-born observations, provided those reasonably approximate the ideal situation......Geomagnetic field modeling consists in converting large numbers of magnetic observations into a linear combination of elementary mathematical functions that best describes those observations. The set of numerical coefficients defining this linear combination is then what one refers...... be directly measured. In this chapter, the mathematical foundation of global (as opposed to regional) geomagnetic field modeling is reviewed, and the spatial modeling of the field in spherical coordinates is focused. Time can be dealt with as an independent variable and is not explicitly considered...
Effectiveness of Peer Education Involving the use of Theoretical Models
2008-01-01
The effectiveness of health education among university students who received peer-support training was investigated using four theoretical models : the health belief model, the self-efficacy model, social support and the transtheoretical model of health behavior change. Results suggested that the four theoretical models were useful in evaluating the effect of peer education as an alternative assessment tool. In light of this, it is suggested that the use of the theoretical models may facilita...
The irregularities of the sunspot cycle and their theoretical modelling
Choudhuri, Arnab Rai
2013-01-01
The 11-year sunspot cycle has many irregularities, the most promi- nent amongst them being the grand minima when sunspots may not be seen for several cycles. After summarizing the relevant observational data about the irregularities, we introduce the flux transport dynamo model, the currently most successful theoretical model for explaining the 11-year sunspot cycle. Then we analyze the respective roles of nonlinearities and random fluctuations in creating the irregularities. We also discuss how it has recently been realized that the fluctuations in meridional circula- tion also can be a source of irregularities. We end by pointing out that fluctuations in the poloidal field generation and fluctuations in meridional circulation together can explain the occurrences of grand minima.
Information-Theoretic Perspectives on Geophysical Models
Nearing, Grey
2016-04-01
practice of science (except by Gong et al., 2013, whose fundamental insight is the basis for this talk), and here I offer two examples of practical methods that scientists might use to approximately measure ontological information. I place this practical discussion in the context of several recent and high-profile experiments that have found that simple out-of-sample statistical models typically (vastly) outperform our most sophisticated terrestrial hydrology models. I offer some perspective on several open questions about how to use these findings to improve our models and understanding of these systems. Cartwright, N. (1983) How the Laws of Physics Lie. New York, NY: Cambridge Univ Press. Clark, M. P., Kavetski, D. and Fenicia, F. (2011) 'Pursuing the method of multiple working hypotheses for hydrological modeling', Water Resources Research, 47(9). Cover, T. M. and Thomas, J. A. (1991) Elements of Information Theory. New York, NY: Wiley-Interscience. Cox, R. T. (1946) 'Probability, frequency and reasonable expectation', American Journal of Physics, 14, pp. 1-13. Csiszár, I. (1972) 'A Class of Measures of Informativity of Observation Channels', Periodica Mathematica Hungarica, 2(1), pp. 191-213. Davies, P. C. W. (1990) 'Why is the physical world so comprehensible', Complexity, entropy and the physics of information, pp. 61-70. Gong, W., Gupta, H. V., Yang, D., Sricharan, K. and Hero, A. O. (2013) 'Estimating Epistemic & Aleatory Uncertainties During Hydrologic Modeling: An Information Theoretic Approach', Water Resources Research, 49(4), pp. 2253-2273. Jaynes, E. T. (2003) Probability Theory: The Logic of Science. New York, NY: Cambridge University Press. Nearing, G. S. and Gupta, H. V. (2015) 'The quantity and quality of information in hydrologic models', Water Resources Research, 51(1), pp. 524-538. Popper, K. R. (2002) The Logic of Scientific Discovery. New York: Routledge. Van Horn, K. S. (2003) 'Constructing a logic of plausible inference: a guide to cox's theorem
Theoretical modeling techniques and their impact on tumor immunology.
Woelke, Anna Lena; Murgueitio, Manuela S; Preissner, Robert
2010-01-01
Currently, cancer is one of the leading causes of death in industrial nations. While conventional cancer treatment usually results in the patient suffering from severe side effects, immunotherapy is a promising alternative. Nevertheless, some questions remain unanswered with regard to using immunotherapy to treat cancer hindering it from being widely established. To help rectify this deficit in knowledge, experimental data, accumulated from a huge number of different studies, can be integrated into theoretical models of the tumor-immune system interaction. Many complex mechanisms in immunology and oncology cannot be measured in experiments, but can be analyzed by mathematical simulations. Using theoretical modeling techniques, general principles of tumor-immune system interactions can be explored and clinical treatment schedules optimized to lower both tumor burden and side effects. In this paper, we aim to explain the main mathematical and computational modeling techniques used in tumor immunology to experimental researchers and clinicians. In addition, we review relevant published work and provide an overview of its impact to the field.
Are invertebrates relevant models in ageing research?
Erdogan, Cihan Suleyman; Hansen, Benni Winding; Vang, Ole
2016-01-01
Ageing is the organisms increased susceptibility to death, which is linked to accumulated damage in the cells and tissues. Ageing is a complex process regulated by crosstalk of various pathways in the cells. Ageing is highly regulated by the Target of Rapamycin (TOR) pathway activity. TOR...... the molecular mechanisms underlying the ageing process faster than mammal systems. Inhibition of the TOR pathway activity via either genetic manipulation or rapamycin increases lifespan profoundly in most invertebrate model organisms. This contribution will review the recent findings in invertebrates concerning...... the TOR pathway and effects of TOR inhibition by rapamycin on lifespan. Besides some contradictory results, the majority points out that rapamycin induces longevity. This suggests that administration of rapamycin in invertebrates is a promising tool for pursuing the scientific puzzle of lifespan...
McClellan, Jeffrey L.
2007-01-01
Servant. This novel actively portrays Greenleaf's concept of servant leadership by describing the extracurricular work of a university professor. Consequently, some scholars have demonstrated the relevance of servant leadership to classroom instruction (Powers & Moore, 2005). However, it was not as an instructor, but as an advisor that the…
Patel, Umang R., E-mail: umangpatel193@yahoo.ca [Gandhinagar Institute of Technology, Moti Bhoyan, Gandhinagar-382721, Gujarat (India); Sardar Patel University, Vallabh Vidyanagar-388120, Gujarat (India); Joshipura, K. N.; Pandya, Siddharth H. [Sardar Patel University, Vallabh Vidyanagar-388120, Gujarat (India); Kothari, Harshit N. [Universal College of Engineering and Technology, Moti Bhoyan, Gandhinagar-382721, Gujarat (India)
2014-01-28
In this paper, we report theoretical electron impact ionization cross sections from threshold to 2000 eV for isocarbonic open chain molecules C{sub 4}H{sub 6}, C{sub 4}H{sub 8}, C{sub 4}F{sub 6} including their isomers, and closed chain molecules c-C{sub 4}H{sub 8} and c-C{sub 4}F{sub 8}. Theoretical formalism employed presently, viz., Complex Scattering Potential-ionization contribution method has been used successfully for a variety of polyatomic molecules. The present ionization calculations are very important since results available for the studied targets are either scarce or none. Our work affords comparison of C{sub 4} containing hydrocarbon versus fluorocarbon molecules. Comparisons of the present ionization cross sections are made wherever possible, and new ionization data are also presented.
An information theoretic approach for combining neural network process models.
Sridhar, D V.; Bartlett, E B.; Seagrave, R C.
1999-07-01
Typically neural network modelers in chemical engineering focus on identifying and using a single, hopefully optimal, neural network model. Using a single optimal model implicitly assumes that one neural network model can extract all the information available in a given data set and that the other candidate models are redundant. In general, there is no assurance that any individual model has extracted all relevant information from the data set. Recently, Wolpert (Neural Networks, 5(2), 241 (1992)) proposed the idea of stacked generalization to combine multiple models. Sridhar, Seagrave and Barlett (AIChE J., 42, 2529 (1996)) implemented the stacked generalization for neural network models by integrating multiple neural networks into an architecture known as stacked neural networks (SNNs). SNNs consist of a combination of the candidate neural networks and were shown to provide improved modeling of chemical processes. However, in Sridhar's work SNNs were limited to using a linear combination of artificial neural networks. While a linear combination is simple and easy to use, it can utilize only those model outputs that have a high linear correlation to the output. Models that are useful in a nonlinear sense are wasted if a linear combination is used. In this work we propose an information theoretic stacking (ITS) algorithm for combining neural network models. The ITS algorithm identifies and combines useful models regardless of the nature of their relationship to the actual output. The power of the ITS algorithm is demonstrated through three examples including application to a dynamic process modeling problem. The results obtained demonstrate that the SNNs developed using the ITS algorithm can achieve highly improved performance as compared to selecting and using a single hopefully optimal network or using SNNs based on a linear combination of neural networks.
How prayer heals: a theoretical model.
Levin, J S
1996-01-01
This article presents a theoretical model that outlines various possible explanations for the healing effects of prayer. Four classes of mechanisms are defined on the basis of whether healing has naturalistic or supernatural origins and whether it operates locally or nonlocally. Through this framework, most of the currently proposed hypotheses for understanding absent healing and other related phenomena-hypotheses that invoke such concepts as subtle energy, psi, consciousness, morphic fields, and extended mind-are shown to be no less naturalistic than the Newtonian, mechanistic forces of allopathic biomedicine so often derided for their materialism. In proposing that prayer may heal through nonlocal means according to mechanisms and theories proposed by the new physics, Dossey is almost alone among medical scholars in suggesting the possible limitations and inadequacies of hypotheses based on energies, forces, and fields. Yet even such nonlocal effects can be conceived of as naturalistic; that is, they are explained by physical laws that may be unbelievable or unfamiliar to most physicians but that are nonetheless becoming recognized as operant laws of the natural universe. The concept of the supernatural, however, is something altogether different, and is, by definition, outside of or beyond nature. Herein may reside an either wholly or partly transcendent Creator-God who is believed by many to heal through means that transcend the laws of the created universe, both its local and nonlocal elements, and that are thus inherently inaccessible to and unknowable by science. Such an explanation for the effects of prayer merits consideration and, despite its unprovability by medical science, should not be dismissed out of hand.
Svelle, Stian
2004-07-01
The primary objective of the present work is to obtain new insight into the reaction mechanism of the zeolite catalyzed methanol-to-hydrocarbons (MTH) reaction. It was decided to use both experimental and computational techniques to reach this goal. An investigation of the n-butene + methanol system was therefore initiated. Over time, it became apparent that it was possible to determine the rate for the methylation of n-butene by methanol. The ethene and propene systems were therefore reexamined in order to collect kinetic information also for those cases. With the development of user-friendly quantum chemistry programs such as the Gaussian suite of programs, the possibility of applying quantum chemical methods to many types of problems has become readily available even for non-experts. When performing mechanistic studies, there is quite often a considerable synergy effect when combining experimental and computational approaches. The methylation reactions mentioned above turned out to be an issue well suited for quantum chemical investigations. The incentive for examining the halomethane reactivity was the clear analogy to the MTH reaction system. Alkene dimerization was also a reaction readily examined with quantum chemistry. As discussed in the introduction of this thesis, polymethylbenzenes, or their cationic counterparts, are suspected to be key intermediates in the MTH reaction. It was therefore decided to investigate the intrinsic reactivity of these species in the gas-phase by employing sophisticated mass spectrometric (MS) techniques in collaboration with the MS group at the Department of Chemistry, University of Oslo The data thus obtained will also be compared with results from an ongoing computational study on gas phase polymethylbenzenium reactivity. 6 papers presenting various studies are included. The titles are: 1) A Theoretical Investigation of the Methylation of Alkenes with Methanol over Acidic Zeolites. 2) A Theoretical Investigation of the
Explaining clinical behaviors using multiple theoretical models.
Eccles, Martin P; Grimshaw, Jeremy M; MacLennan, Graeme; Bonetti, Debbie; Glidewell, Liz; Pitts, Nigel B; Steen, Nick; Thomas, Ruth; Walker, Anne; Johnston, Marie
2012-10-17
In the field of implementation research, there is an increased interest in use of theory when designing implementation research studies involving behavior change. In 2003, we initiated a series of five studies to establish a scientific rationale for interventions to translate research findings into clinical practice by exploring the performance of a number of different, commonly used, overlapping behavioral theories and models. We reflect on the strengths and weaknesses of the methods, the performance of the theories, and consider where these methods sit alongside the range of methods for studying healthcare professional behavior change. These were five studies of the theory-based cognitions and clinical behaviors (taking dental radiographs, performing dental restorations, placing fissure sealants, managing upper respiratory tract infections without prescribing antibiotics, managing low back pain without ordering lumbar spine x-rays) of random samples of primary care dentists and physicians. Measures were derived for the explanatory theoretical constructs in the Theory of Planned Behavior (TPB), Social Cognitive Theory (SCT), and Illness Representations specified by the Common Sense Self Regulation Model (CSSRM). We constructed self-report measures of two constructs from Learning Theory (LT), a measure of Implementation Intentions (II), and the Precaution Adoption Process. We collected data on theory-based cognitions (explanatory measures) and two interim outcome measures (stated behavioral intention and simulated behavior) by postal questionnaire survey during the 12-month period to which objective measures of behavior (collected from routine administrative sources) were related. Planned analyses explored the predictive value of theories in explaining variance in intention, behavioral simulation and behavior. Response rates across the five surveys ranged from 21% to 48%; we achieved the target sample size for three of the five surveys. For the predictor variables
Explaining clinical behaviors using multiple theoretical models
Eccles Martin P
2012-10-01
Full Text Available Abstract Background In the field of implementation research, there is an increased interest in use of theory when designing implementation research studies involving behavior change. In 2003, we initiated a series of five studies to establish a scientific rationale for interventions to translate research findings into clinical practice by exploring the performance of a number of different, commonly used, overlapping behavioral theories and models. We reflect on the strengths and weaknesses of the methods, the performance of the theories, and consider where these methods sit alongside the range of methods for studying healthcare professional behavior change. Methods These were five studies of the theory-based cognitions and clinical behaviors (taking dental radiographs, performing dental restorations, placing fissure sealants, managing upper respiratory tract infections without prescribing antibiotics, managing low back pain without ordering lumbar spine x-rays of random samples of primary care dentists and physicians. Measures were derived for the explanatory theoretical constructs in the Theory of Planned Behavior (TPB, Social Cognitive Theory (SCT, and Illness Representations specified by the Common Sense Self Regulation Model (CSSRM. We constructed self-report measures of two constructs from Learning Theory (LT, a measure of Implementation Intentions (II, and the Precaution Adoption Process. We collected data on theory-based cognitions (explanatory measures and two interim outcome measures (stated behavioral intention and simulated behavior by postal questionnaire survey during the 12-month period to which objective measures of behavior (collected from routine administrative sources were related. Planned analyses explored the predictive value of theories in explaining variance in intention, behavioral simulation and behavior. Results Response rates across the five surveys ranged from 21% to 48%; we achieved the target sample size for three of
Guo, Jing; McLeod, Poppy Lauretta
2014-01-01
Drawing upon the Search for Ideas in Associative Memory (SIAM) model as the theoretical framework, the impact of heterogeneity and topic relevance of visual stimuli on ideation performance was examined. Results from a laboratory experiment showed that visual stimuli increased productivity and diversity of idea generation, that relevance to the…
A Compositional Relevance Model for Adaptive Information Retrieval
Mathe, Nathalie; Chen, James; Lu, Henry, Jr. (Technical Monitor)
1994-01-01
There is a growing need for rapid and effective access to information in large electronic documentation systems. Access can be facilitated if information relevant in the current problem solving context can be automatically supplied to the user. This includes information relevant to particular user profiles, tasks being performed, and problems being solved. However most of this knowledge on contextual relevance is not found within the contents of documents, and current hypermedia tools do not provide any easy mechanism to let users add this knowledge to their documents. We propose a compositional relevance network to automatically acquire the context in which previous information was found relevant. The model records information on the relevance of references based on user feedback for specific queries and contexts. It also generalizes such information to derive relevant references for similar queries and contexts. This model lets users filter information by context of relevance, build personalized views of documents over time, and share their views with other users. It also applies to any type of multimedia information. Compared to other approaches, it is less costly and doesn't require any a priori statistical computation, nor an extended training period. It is currently being implemented into the Computer Integrated Documentation system which enables integration of various technical documents in a hypertext framework.
Reyes-García Victoria
2010-11-01
Full Text Available Abstract Background Ethnopharmacology is at the intersection of the medical, natural, and social sciences. Despite its interdisciplinary nature, most ethnopharmacological research has been based on the combination of the chemical, biological, and pharmacological sciences. Far less attention has been given to the social sciences, including anthropology and the study of traditional knowledge systems. Methods I reviewed the literature on traditional knowledge systems highlighting its potential theoretical and methodological contributions to ethnopharmacology. Results I discuss three potential theoretical contributions of traditional knowledge systems to ethnopharmacological research. First, while many plants used in indigenous pharmacopoeias have active compounds, those compounds do not always act alone in indigenous healing systems. Research highlights the holistic nature of traditional knowledge systems and helps understand plant's efficacy in its cultural context. Second, research on traditional knowledge systems can improve our understanding of how ethnopharmacological knowledge is distributed in a society, and who benefits from it. Third, research on traditional knowledge systems can enhance the study of the social relations that enable the generation, maintenance, spread, and devolution of cultural traits and innovations, including ethnopharmacological knowledge. At a methodological level, some ethnopharmacologists have used anthropological tools to understand the context of plant use and local meanings of health and disease. I discuss two more potential methodological contributions of research on traditional knowledge systems to ethnopharmacological research. First, traditional knowledge systems research has developed methods that would help ethnopharmacologists understand how people classify illnesses and remedies, a fundamental aspect of folk medicinal plant selection criteria. Second, ethnopharmacologists could also borrow methods derived
Theoretical and experimental FUZZY modelling of building thermal dynamic response
Skrjanc, Igor; Zupancic, Borut [Ljubljana Univ., Faculty of Electrical Engineering, Ljubljana (Slovenia); Furlan, Bostjan; Krainer, Ales [Ljubljana Univ., Faculty of Civil Engineering, Ljubljana (Slovenia)
2001-11-01
In this paper this main advantages and disadvantages of two different types of modelling: theoretical and experimental are presented and discussed. The theoretical modelling is based on energy balances, which gives the overall model described by differential equations. On the basis of developed theoretical model a complex simulator in the MATLAB-Simulink environment was implemented. The second part is devoted to experimental modelling. In this paper a fuzzy model represented by non-linear relations between input and output variables obtained by least-squares optimisation method is investigated. (Author)
A theoretical model of atmospheric ozone depletion
Midya, S. K.; Jana, P. K.; Lahiri, T.
1994-01-01
A critical study on different ozone depletion and formation processes has been made and following important results are obtained: (i) From analysis it is shown that O3 concentration will decrease very minutely with time for normal atmosphere when [O], [O2] and UV-radiation remain constant. (ii) An empirical equation is established theoretically between the variation of ozone concentration and time. (iii) Special ozone depletion processes are responsible for the dramatic decrease of O3-concentration at Antarctica.
High Tc Superconductor Theoretical Models and Electromagnetic Flux Characteristics
JIN Jian-xun
2006-01-01
High Tc Superconductors (HTS) have special electromagnetic characteristics and phenomena. Effort has been made in order to theoretically understand the applied HTS superconductivity and HTS behaviors for practical applications, various theoretical models related to the HTS electromagnetic properties have been developed. The theoretical models and analytic methods are summarized with regard to understanding the HTS magnetic flux characteristic which is one of the most critical issues related to HTS applications such as for HTS magnetic levitation application.
Modeling of alkynes: synthesis and theoretical properties
Renato Rosseto
2003-06-01
Full Text Available In this paper we present the synthesis and simulation of alkynes derivatives. Semiempirical calculations were carried out for the ground and first excited states, including the spectroscopic properties of the absorption and emission (fluorescence and phosphorescence spectra by INDO/S-CI and DNdM-INDO/S-CI methods with geometries fully optimized by PM3/CI. The fact that the theoretical spectra are in accord with the experimental absorption spectra gives us a new possible approach on how structure modifications could affect the non-linear optical properties of alkynes.
Aguinis, Herman; Molina-Azorín, José F.
2015-01-01
The microfoundations research agenda presents an expanded theoretical perspective because it considers individuals, their characteristics, and their interactions as relevant variables to help us understand firm-level strategic issues. However, microfoundations empirical research faces unique challenges because processes take place at different levels of analysis and these multilevel processes must be considered simultaneously. We describe multilevel modeling and mixed methods as methodologica...
Aguinis, Herman; Molina-Azorín, José F.
2015-01-01
The microfoundations research agenda presents an expanded theoretical perspective because it considers individuals, their characteristics, and their interactions as relevant variables to help us understand firm-level strategic issues. However, microfoundations empirical research faces unique challenges because processes take place at different levels of analysis and these multilevel processes must be considered simultaneously. We describe multilevel modeling and mixed methods as methodologica...
Organizational effectiveness of coalition operations' headquarters : A theoretical model
Vogler-Bisig, E.; Blais, A.R.; Hof, T.; Tresch, T.S.; Seiler, S.; Yanakiev, Y.
2012-01-01
Purpose - This article describes a theoretical model that allows understanding, explaining, and measuring the perceived organizational effectiveness of multinational coalition operations' headquarters. Design/methodology/approach - The proposed model is based on subject matter experts' opinions and
POSITIVE LEADERSHIP MODELS: THEORETICAL FRAMEWORK AND RESEARCH
Javier Blanch, Francisco Gil
2016-09-01
Full Text Available The objective of this article is twofold; firstly, we establish the theoretical boundaries of positive leadership and the reasons for its emergence. It is related to the new paradigm of positive psychology that has recently been shaping the scope of organizational knowledge. This conceptual framework has triggered the development of the various forms of positive leadership (i.e. transformational, servant, spiritual, authentic, and positive. Although the construct does not seem univocally defined, these different types of leadership overlap and share a significant affinity. Secondly, we review the empirical evidence that shows the impact of positive leadership in organizations and we highlight the positive relationship between these forms of leadership and key positive organizational variables. Lastly, we analyse future research areas in order to further develop this concept.
Emel'yanenko, Vladimir N; Zaitsau, Dzmitry H; Shoifet, Evgeni; Meurer, Florian; Verevkin, Sergey P; Schick, Christoph; Held, Christoph
2015-09-17
The thermochemical properties available in the literature for adenine and cytosine are in disarray. A new condensed phase standard (p° = 0.1 MPa) molar enthalpy of formation at T = 298.15 K was measured by using combustion calorimetry. New molar enthalpies of sublimation were derived from the temperature dependence of vapor pressure measured by transpiration and by the quarz-crystal microbalance technique. The heat capacities of crystalline adenine and cytosine were measured by temperature-modulated DSC. Thermodynamic data on adenine and cytosine available in the literature were collected, evaluated, and combined with our experimental results. Thus, the evaluated collection of data together with the new experimental results reported here has helped to resolve contradictions in the available enthalpies of formation. A set of reliable thermochemical data is recommended for adenine and cytosine for further thermochemical calculations. Quantum-chemical calculations of the gas phase molar enthalpies of formation of adenine and cytosine have been performed by using the G4 method and results were in excellent agreement with the recommended experimental data. The standard molar entropies of formation and the standard molar Gibbs functions of formation in crystal and gas state have been calculated. Experimental vapor-pressure data measured in this work were used to estimate pure-component PC-SAFT parameters. This allowed modeling solubility of adenine and cytosine in water over the temperature interval 278-310 K.
A Theoretic Model of Transport Logistics Demand
Natalija Jolić
2006-01-01
Full Text Available Concerning transport logistics as relation between transportand integrated approaches to logistics, some transport and logisticsspecialists consider the tenn tautological. However,transport is one of the components of logistics, along with inventories,resources, warehousing, infonnation and goods handling.Transport logistics considers wider commercial and operationalframeworks within which the flow of goods is plannedand managed. The demand for transport logistics services canbe valorised as highly qualitative, differentiated and derived.While researching transport phenomenon the implementationof models is inevitable and demand models highly desirable. Asa contribution to transport modelling this paper improves decisionmaking and planning in the transport logistics field.
Dark energy observational evidence and theoretical models
Novosyadlyj, B; Shtanov, Yu; Zhuk, A
2013-01-01
The book elucidates the current state of the dark energy problem and presents the results of the authors, who work in this area. It describes the observational evidence for the existence of dark energy, the methods and results of constraining of its parameters, modeling of dark energy by scalar fields, the space-times with extra spatial dimensions, especially Kaluza---Klein models, the braneworld models with a single extra dimension as well as the problems of positive definition of gravitational energy in General Relativity, energy conditions and consequences of their violation in the presence of dark energy. This monograph is intended for science professionals, educators and graduate students, specializing in general relativity, cosmology, field theory and particle physics.
Theoretical Modelling of Intercultural Communication Process
Mariia Soter
2016-08-01
Full Text Available The definition of the concepts of “communication”, “intercultural communication”, “model of communication” are analyzed in the article. The basic components of the communication process are singled out. The model of intercultural communication is developed. Communicative, behavioral and complex skills for optimal organization of intercultural communication, establishment of productive contact with a foreign partner to achieve mutual understanding, searching for acceptable ways of organizing interaction and cooperation for both communicants are highlighted in the article. It is noted that intercultural communication through interaction between people affects the development of different cultures’ aspects.
Theoretical analysis and modeling for nanoelectronics
Baccarani, Giorgio; Gnani, Elena; Gnudi, Antonio; Reggiani, Susanna
2016-11-01
In this paper we review the evolution of Microelectronics and its transformation into Nanoelectronics, following the predictions of Moore's law, and some of the issues related with this evolution. Next, we discuss the requirements of device modeling and the solutions proposed throughout the years to address the physical effects related with an extreme device miniaturization, such as hot-electron effects, band splitting into multiple sub-bands, quasi-ballistic transport and electron tunneling. The most important physical models are shortly highlighted, and a few simulation results of heterojunction TFETs are reported and discussed.
SOME THEORETICAL MODELS EXPLAINING ADVERTISING EFFECTS
Vasilica Magdalena SOMEŞFĂLEAN
2014-06-01
Full Text Available Persuade clients is still the main focus of the companies, using a set of methods and techniques designed to influence their behavior, in order to obtain better results (profits over a longer period of time. Since the late nineteenth - early twentieth century, the american E.St.Elmo Lewis, considered a pioneer in advertising and sales, developed the first theory, AIDA model, later used by marketers and advertisers to develop a marketing communications strategy. Later studies have developed other models that are the main subject of this research, which explains how and why persuasive communication works, to understand why some approaches are effective and others are not.
A Theoretical Model for Selective Exposure Research.
Roloff, Michael E.; Noland, Mark
This study tests the basic assumptions underlying Fishbein's Model of Attitudes by correlating an individual's selective exposure to types of television programs (situation comedies, family drama, and action/adventure) with the attitudinal similarity between individual attitudes and attitudes characterized on the programs. Twenty-three college…
The development of a theoretical model to investigate factors ...
The development of a theoretical model to investigate factors associated with ... major household appliance market: An integrative conceptual approach. ... disadvantaged consumers gain spending power and access to electricity supply.
Theoretical models in low-Reynolds-number locomotion
Pak, On Shun
2014-01-01
The locomotion of microorganisms in fluids is ubiquitous and plays an important role in numerous biological processes. In this chapter we present an overview of theoretical modeling for low-Reynolds-number locomotion.
Theoretical model for a Stark anomalous dispersion optical filter
Yin, B.; Shay, T. M.
1993-01-01
A theoretical model for the first atomic Stark anomalous dispersion optical filter is reported. The results show the filter may serve as a widely tunable narrow bandwidth and high throughput optical filter for freespace laser communications and remote sensing.
A Theoretical Study of Subsurface Drainage Model Simulation of ...
A Theoretical Study of Subsurface Drainage Model Simulation of Drainage Flow and ... of subsurface drain spacing, evapotranspiration and irrigation water quality on ... The study was carried out on a conceptual uniform homogenous irrigated ...
Theoretical Tinnitus framework: A Neurofunctional Model
Iman Ghodratitoostani
2016-08-01
Full Text Available Subjective tinnitus is the conscious (attended awareness perception of sound in the absence of an external source and can be classified as an auditory phantom perception. The current tinnitus development models depend on the role of external events congruently paired with the causal physical events that precipitate the phantom perception. We propose a novel Neurofunctional tinnitus model to indicate that the conscious perception of phantom sound is essential in activating the cognitive-emotional value. The cognitive-emotional value plays a crucial role in governing attention allocation as well as developing annoyance within tinnitus clinical distress. Structurally, the Neurofunctional tinnitus model includes the peripheral auditory system, the thalamus, the limbic system, brain stem, basal ganglia, striatum and the auditory along with prefrontal cortices. Functionally, we assume the model includes presence of continuous or intermittent abnormal signals at the peripheral auditory system or midbrain auditory paths. Depending on the availability of attentional resources, the signals may or may not be perceived. The cognitive valuation process strengthens the lateral-inhibition and noise canceling mechanisms in the mid-brain, which leads to the cessation of sound perception and renders the signal evaluation irrelevant. However, the sourceless sound is eventually perceived and can be cognitively interpreted as suspicious or an indication of a disease in which the cortical top-down processes weaken the noise canceling effects. This results in an increase in cognitive and emotional negative reactions such as depression and anxiety. The negative or positive cognitive-emotional feedbacks within the top-down approach may have no relation to the previous experience of the patients. They can also be associated with aversive stimuli similar to abnormal neural activity in generating the phantom sound. Cognitive and emotional reactions depend on general
Theoretical Tinnitus Framework: A Neurofunctional Model.
Ghodratitoostani, Iman; Zana, Yossi; Delbem, Alexandre C B; Sani, Siamak S; Ekhtiari, Hamed; Sanchez, Tanit G
2016-01-01
Subjective tinnitus is the conscious (attended) awareness perception of sound in the absence of an external source and can be classified as an auditory phantom perception. Earlier literature establishes three distinct states of conscious perception as unattended, attended, and attended awareness conscious perception. The current tinnitus development models depend on the role of external events congruently paired with the causal physical events that precipitate the phantom perception. We propose a novel Neurofunctional Tinnitus Model to indicate that the conscious (attended) awareness perception of phantom sound is essential in activating the cognitive-emotional value. The cognitive-emotional value plays a crucial role in governing attention allocation as well as developing annoyance within tinnitus clinical distress. Structurally, the Neurofunctional Tinnitus Model includes the peripheral auditory system, the thalamus, the limbic system, brainstem, basal ganglia, striatum, and the auditory along with prefrontal cortices. Functionally, we assume the model includes presence of continuous or intermittent abnormal signals at the peripheral auditory system or midbrain auditory paths. Depending on the availability of attentional resources, the signals may or may not be perceived. The cognitive valuation process strengthens the lateral-inhibition and noise canceling mechanisms in the mid-brain, which leads to the cessation of sound perception and renders the signal evaluation irrelevant. However, the "sourceless" sound is eventually perceived and can be cognitively interpreted as suspicious or an indication of a disease in which the cortical top-down processes weaken the noise canceling effects. This results in an increase in cognitive and emotional negative reactions such as depression and anxiety. The negative or positive cognitive-emotional feedbacks within the top-down approach may have no relation to the previous experience of the patients. They can also be
Choking under pressure: theoretical models and interventions.
Mesagno, Christopher; Beckmann, Juergen
2017-08-01
In sport, choking under pressure is a major concern for athletes, coaches and sport psychologists because athletes fail to meet self-imposed performance expectations in critical situations (when it counts the most), which is devastating and embarrassing. Researchers have debated choking under pressure definitions, identified personality characteristics that exacerbate choking outcomes, and examined models to determine mechanisms for choking. Based on these investigations, several interventions to prevent choking have been developed and tested. In this review, we specifically discuss current self-presentation and attention models and theory-driven interventions that help to alleviate choking in order to facilitate the understanding of this complex phenomenon by athletes, sport psychologists and researchers. Copyright © 2017 Elsevier Ltd. All rights reserved.
SOME THEORETICAL MODELS EXPLAINING ADVERTISING EFFECTS
Vasilica Magdalena SOMEŞFĂLEAN
2014-01-01
Persuade clients is still the main focus of the companies, using a set of methods and techniques designed to influence their behavior, in order to obtain better results (profits) over a longer period of time. Since the late nineteenth - early twentieth century, the american E.St.Elmo Lewis, considered a pioneer in advertising and sales, developed the first theory, AIDA model, later used by marketers and advertisers to develop a marketing communications strategy. Later studies have developed o...
Theoretical modeling of prion disease incubation
Kulkarni, R. V.; Slepoy, A.; Singh, R. R. P.; Cox, D. L.; Mobley, D.; Pázmándi, F.
2001-01-01
We present a theory for the laboratory and epidemiological data for incubation times in infectious prion diseases. The central feature of our model is that slow growth of misfolded protein-aggregates from small initial seeds controls the `latent' or `lag' phase, whereas aggregate-fissioning and subsequent spreading leads to an exponential growth or doubling phase. Such a general framework can account for many features of prion diseases including the striking reproducibility of incubation time...
A theoretical model of infant incubator dynamics.
Simon, B N; Reddy, N P; Kantak, A
1994-08-01
A spatially lumped mathematical model was developed and used for a computer simulation of the neonate-incubator system for parametric analysis of the factors that influence neonatal thermo-regulation. The simulation examined the effects of the following parameters: (1) size of the infant; (2) respiratory rate; (3) metabolic rate; (4) heart rate; (5) thermal properties of the mattress; (6) specific heat capacity of the incubator wall; (7) air flow rate; (8) heater control mechanisms.
Voronoi cell patterns: Theoretical model and applications
González, Diego Luis; Einstein, T. L.
2011-11-01
We use a simple fragmentation model to describe the statistical behavior of the Voronoi cell patterns generated by a homogeneous and isotropic set of points in 1D and in 2D. In particular, we are interested in the distribution of sizes of these Voronoi cells. Our model is completely defined by two probability distributions in 1D and again in 2D, the probability to add a new point inside an existing cell and the probability that this new point is at a particular position relative to the preexisting point inside this cell. In 1D the first distribution depends on a single parameter while the second distribution is defined through a fragmentation kernel; in 2D both distributions depend on a single parameter. The fragmentation kernel and the control parameters are closely related to the physical properties of the specific system under study. We use our model to describe the Voronoi cell patterns of several systems. Specifically, we study the island nucleation with irreversible attachment, the 1D car-parking problem, the formation of second-level administrative divisions, and the pattern formed by the Paris Métro stations.
Confronting Substellar Theoretical Models with Stellar Ages
Dupuy, Trent J; Ireland, Michael J
2009-01-01
By definition, brown dwarfs never reach the main-sequence, cooling and dimming over their entire lifetime, thus making substellar models challenging to test because of the strong dependence on age. Currently, most brown dwarfs with independently determined ages are companions to nearby stars, so stellar ages are at the heart of the effort to test substellar models. However, these models are only fully constrained if both the mass and age are known. We have used the Keck adaptive optics system to monitor the orbit of HD 130948BC, a brown dwarf binary that is a companion to the young solar analog HD 130948A. The total dynamical mass of 0.109+/-0.003 Msun shows that both components are substellar, and the ensemble of available age indicators from the primary star suggests an age comparable to the Hyades, with the most precise age being 0.79 Gyr based on gyrochronology. Therefore, HD 130948BC is unique among field L and T dwarfs as it possesses a well-determined mass, luminosity, and age. Our results indicate tha...
A Game Theoretic Model Of Strategic Conflict In Cyberspace
2012-01-01
by Shiva , Dasgupta, and Wu (2010). They develop a taxonomy of game theoretic models with two broad categories: Static versus Dynamic. A “one shot...to date on cyber conflict deals only with noncooperative games. In the taxonomy of Shiva et al. (2010) our proposed model is a noncooperative, dynamic...approach for cyber situational awareness. SPIE’s Defense and Security Symposium, Orlando, FL. Shiva , S., Dasgupta, D., & Wu, O. (2010). Game theoretic
Relevant Criteria for Testing the Quality of Turbulence Models
Frandsen, Sten; Jørgensen, Hans E.; Sørensen, John Dalsgaard
2007-01-01
turbines when seeking wind characteristics that correspond to one blade and the entire rotor, respectively. For heights exceeding 50-60m the gust factor increases with wind speed. For heights larger the 60-80m, present assumptions on the value of the gust factor are significantly conservative, both for 3......Seeking relevant criteria for testing the quality of turbulence models, the scale of turbulence and the gust factor have been estimated from data and compared with predictions from first-order models of these two quantities. It is found that the mean of the measured length scales is approx. 10......% smaller than the IEC model, for wind turbine hub height levels. The mean is only marginally dependent on trends in time series. It is also found that the coefficient of variation of the measured length scales is about 50%. 3sec and 10sec pre-averaging of wind speed data are relevant for MW-size wind...
Theoretical Modelling of Sound Radiation from Plate
Zaman, I.; Rozlan, S. A. M.; Yusoff, A.; Madlan, M. A.; Chan, S. W.
2017-01-01
Recently the development of aerospace, automotive and building industries demands the use of lightweight materials such as thin plates. However, the plates can possibly add to significant vibration and sound radiation, which eventually lead to increased noise in the community. So, in this study, the fundamental concept of sound pressure radiated from a simply-supported thin plate (SSP) was analyzed using the derivation of mathematical equations and numerical simulation of ANSYS®. The solution to mathematical equations of sound radiated from a SSP was visualized using MATLAB®. The responses of sound pressure level were measured at far field as well as near field in the frequency range of 0-200 Hz. Result shows that there are four resonance frequencies; 12 Hz, 60 Hz, 106 Hz and 158 Hz were identified which represented by the total number of the peaks in the frequency response function graph. The outcome also indicates that the mathematical derivation correlated well with the simulation model of ANSYS® in which the error found is less than 10%. It can be concluded that the obtained model is reliable and can be applied for further analysis such as to reduce noise emitted from a vibrating thin plate.
Theoretical postulation of PLC channel model
Alexandru Ionuţ Chiuţă
2009-05-01
Full Text Available The objective of this document is to supply atheoretical basis for modelling the communicationlinks over powerlines. A comprehensive summary oftransmission properties and the noise scenario onpublic mains supply when used for data transmissionare given.Different PLC models - PLC channel, noise inPLC channel, coupling units, filters and conditioningdevices – will be created and they will be used tosimulate the PLC channel.PLC applications will have to work at veryunusual channels, solely designed for optimalelectrical power transportation, completelydisregarding signal transmission at high frequencies.It is shown that the typical properties aredescribed by transfer functions and noise scenariostypical for access and inhouse networks. The generaltransfer function for different channel types is derivedand, since an emulation system should reproducetypical classes of channels rather than singlemeasurements, the transfer function is concretisedwith reference channels. These are later serving asbasis for development of channel simulators andchannel emulators. Special attention is paid tomodelling of aperiodic impulsive noise since PLCsystems are reacting very sensitive to them and thisclass of noise has been insufficiently considered so far.
From theoretical model to practical use:
Bjørk, Ida Torunn; Lomborg, Kirsten; Nielsen, Carsten Munch
2013-01-01
passive diffusion strategies with interaction and teamwork between stakeholders. The use of knowledge creates feedback that might have consequences for the refinement and tailoring of that same knowledge itself. With end-users in mind, several heuristics were used by the research group to increase clarity...... of the model and to tailor the implementation of knowledge to the users. Implications for nursing. This article illustrates the need for enduring collaboration between stakeholders to promote the process of knowledge translation. Translation of research knowledge into practice is a time-consuming process...... that is enhanced when appropriate support is given by leaders in the involved facilities. Conclusion. Knowledge translation is a time-consuming and collaborative endeavour. On the basis of our experience we advocate the implementation and use of a conceptual framework for the entire process of knowledge...
Theoretical model and quantification of reflectance photometer
Lihua Huang; Youbao Zhang; Chengke Xie; Jianfeng Qu; Huijie Huang; Xiangzhao Wang
2009-01-01
@@ The surface morphology of lateral flow (LF) strip is examined by scanning electron microscope (SEM) and the diffuse reflection of porous strip with or without nanogold particles is investigated.Based on the scattering and absorption of nanogold particles, a reflectance photometer is developed for quantification of LF strip with nanogold particles as reporter.The integration of reflection optical density is to indicate the signals of test line and control line.As an example, serial dilutions of microalbunminuria (MAU) solution are used to calibrate the performance of the reflectance photometer.The dose response curve is fitted with a four-parameter logistic mathematical model for the determination of an unknown MAU concentration.The response curve spans a dynamic range of 5 to 200 μg/ml.The developed reflectance photometer can realize simple and quantitative detection of analyte on nanogold-labeled LF strip.
The Psychopathological Model of Mental Retardation: Theoretical and Therapeutic Considerations.
La Malfa, Giampaolo; Campigli, Marco; Bertelli, Marco; Mangiapane, Antonio; Cabras, Pier Luigi
1997-01-01
Describes a new integrated bio-psycho-social model of etiology for mental retardation. Discusses the problems with current models and the ability of the "universe line" model to integrate data from different research areas, especially cognitive and psychopathologic indicators. Addresses implications of this theoretical approach. (Author/CR)
Dynamics in Higher Education Politics: A Theoretical Model
Kauko, Jaakko
2013-01-01
This article presents a model for analysing dynamics in higher education politics (DHEP). Theoretically the model draws on the conceptual history of political contingency, agenda-setting theories and previous research on higher education dynamics. According to the model, socio-historical complexity can best be analysed along two dimensions: the…
Automatic Relevance Determination for multi-way models
Mørup, Morten; Hansen, Lars Kai
2009-01-01
Estimating the adequate number of components is an important yet difficult problem in multi-way modelling. We demonstrate how a Bayesian framework for model selection based on Automatic Relevance Determination (ARD) can be adapted to the Tucker and CP models. By assigning priors for the model...... parameters and learning the hyperparameters of these priors the method is able to turn off excess components and simplify the core structure at a computational cost of fitting the conventional Tucker/CP model. To investigate the impact of the choice of priors we based the ARD on both Laplace and Gaussian...... of components of data within the Tucker and CP structure. For the Tucker and CP model the approach performs better than heuristics such as the Bayesian Information Criterion, Akaikes Information Criterion, DIFFIT and the numerical convex hull (NumConvHull) while operating only at the cost of estimating...
Information-theoretic model selection applied to supernovae data
Biesiada, M
2007-01-01
There are several different theoretical ideas invoked to explain the dark energy with relatively little guidance of which one of them might be right. Therefore the emphasis of ongoing and forthcoming research in this field shifts from estimating specific parameters of cosmological model to the model selection. In this paper we apply information-theoretic model selection approach based on Akaike criterion as an estimator of Kullback-Leibler entropy. In particular, we present the proper way of ranking the competing models based on Akaike weights (in Bayesian language - posterior probabilities of the models). Out of many particular models of dark energy we focus on four: quintessence, quintessence with time varying equation of state, brane-world and generalized Chaplygin gas model and test them on Riess' Gold sample. As a result we obtain that the best model - in terms of Akaike Criterion - is the quintessence model. The odds suggest that although there exist differences in the support given to specific scenario...
Theoretical Model Calculation for d + 8Li Reaction
HAN Yin-Lu; GUO Hai-Rui; ZHANG Yue; ZHANG Jing-Shang
2008-01-01
Based on the theoretical models for light nuclei, the calculations of reaction cross sections and the angular distributions for d+8Li reaction are performed. Since all of the particle emissions are from the compound nucleus to the discrete levels, the angular momentum coupling effect in pre-equilibrium mechanism is taken into account. The three-body break-up process and the recoil effect are involved. The theoretical calculated results are compared to existing experimental data.
Theoretical Model of Transformation Superlastic Diffusion Bonding for Eutectoid Steel
无
2002-01-01
Based on current theories of diffusion and creep cavity closure at high temperature, a theoretical analysis of phase transformation diffusion bonding for T8/T8 eutectoid steel is carried out. The diffusion bonding is mainly described as two-stage process: Ⅰ The interfacial cavity with shape change from diamond to cylinder.Ⅱ The radius of the cylindrical cavity are reduced and eliminated gradually. A new theoretical model is established for the process of transformation superplastic diffusion bonding (TSDB) ...
A new theoretical model of the quasistatic single-fiber pullout problem: Analysis of stress field
Qing, Hai
2013-01-01
results of the stress distributions, in both fully bonded region and fully debonded region, are presented for a typical glass/epoxy composite system with different fibre volume fraction and model length. In fully bonded region, the theoretical results from present model are more accurate compared......A new theoretical model is developed in order to predict the stress transfer during the quasistatic single-fibre pullout process. The theoretical approach retains all relevant stress and strain components, and satisfies exactly the interfacial continuity conditions and all the stress boundary...... conditions. For both matrix and fibre, the equilibrium equations along radial direction are satisfied strictly, while the equilibrium equations along axial direction are satisfied in the integral forms. Three normal stress-strain relationships are strictly satisfied, while the radial displacement gradient...
Modelling theoretical uncertainties in phenomenological analyses for particle physics
Charles, Jérôme; Niess, Valentin; Silva, Luiz Vale
2016-01-01
The determination of the fundamental parameters of the Standard Model (and its extensions) is often limited by the presence of statistical and theoretical uncertainties. We present several models for the latter uncertainties (random, nuisance, external) in the frequentist framework, and we derive the corresponding $p$-values. In the case of the nuisance approach where theoretical uncertainties are modeled as biases, we highlight the important, but arbitrary, issue of the range of variation chosen for the bias parameters. We introduce the concept of adaptive $p$-value, which is obtained by adjusting the range of variation for the bias according to the significance considered, and which allows us to tackle metrology and exclusion tests with a single and well-defined unified tool, which exhibits interesting frequentist properties. We discuss how the determination of fundamental parameters is impacted by the model chosen for theoretical uncertainties, illustrating several issues with examples from quark flavour p...
Modeling theoretical uncertainties in phenomenological analyses for particle physics
Charles, Jerome [CNRS, Aix-Marseille Univ, Universite de Toulon, CPT UMR 7332, Marseille Cedex 9 (France); Descotes-Genon, Sebastien [CNRS, Univ. Paris-Sud, Universite Paris-Saclay, Laboratoire de Physique Theorique (UMR 8627), Orsay Cedex (France); Niess, Valentin [CNRS/IN2P3, UMR 6533, Laboratoire de Physique Corpusculaire, Aubiere Cedex (France); Silva, Luiz Vale [CNRS, Univ. Paris-Sud, Universite Paris-Saclay, Laboratoire de Physique Theorique (UMR 8627), Orsay Cedex (France); Univ. Paris-Sud, CNRS/IN2P3, Universite Paris-Saclay, Groupe de Physique Theorique, Institut de Physique Nucleaire, Orsay Cedex (France); J. Stefan Institute, Jamova 39, P. O. Box 3000, Ljubljana (Slovenia)
2017-04-15
The determination of the fundamental parameters of the Standard Model (and its extensions) is often limited by the presence of statistical and theoretical uncertainties. We present several models for the latter uncertainties (random, nuisance, external) in the frequentist framework, and we derive the corresponding p values. In the case of the nuisance approach where theoretical uncertainties are modeled as biases, we highlight the important, but arbitrary, issue of the range of variation chosen for the bias parameters. We introduce the concept of adaptive p value, which is obtained by adjusting the range of variation for the bias according to the significance considered, and which allows us to tackle metrology and exclusion tests with a single and well-defined unified tool, which exhibits interesting frequentist properties. We discuss how the determination of fundamental parameters is impacted by the model chosen for theoretical uncertainties, illustrating several issues with examples from quark flavor physics. (orig.)
Hypermedia as an experiential learning tool: a theoretical model
Jose Miguel Baptista Nunes
1996-01-01
Full Text Available The process of methodical design and development is of extreme importance in the production of educational software. However, this process will only be effective, if it is based on a theoretical model that explicitly defines what educational approach is being used and how specific features of the technology can best support it. This paper proposes a theoretical model of how hypermedia can be used as an experiential learning tool. The development of the model was based on a experiential learning approach and simultaneously aims at minimising the inherent problems of hypermedia as the underlying support technology.
Category-theoretic models of linear Abadi & Plotkin Logic
Birkedal, Lars; Møgelberg, Rasmus Ejlers; Lerchedahl Petersen, Rasmus
2008-01-01
This paper presents a sound and complete category-theoretic notion of models for Linear Abadi & Plotkin Logic [Birkedal et al., 2006], a logic suitable for reasoning about parametricity in combination with recursion. A subclass of these called parametric LAPL structures can be seen as an axiomati......This paper presents a sound and complete category-theoretic notion of models for Linear Abadi & Plotkin Logic [Birkedal et al., 2006], a logic suitable for reasoning about parametricity in combination with recursion. A subclass of these called parametric LAPL structures can be seen...... as an axiomatization of domain theoretic models of parametric polymorphism, and we show how to solve general (nested) recursive domain equations in these. parametric LAPL structures constitute a general notion of model of parametricity in a setting with recursion. In future papers we will demonstrate this by showing...... how many different models of parametricity and recursion give rise to parametric LAPL structures, including Simpson and Rosolini’s set theoretic models [Rosolini and Simpson, 2004], a syntactic model based on Lily [Pitts, 2000, Bierman et al., 2000] and a model based on admissible pers over...
Theoretical bases of modeling decision-marketing solutions
Grigoruk Pavel Mikhaylovych
2012-01-01
The paper deals with issues related with theoretical aspects of modelling of marketing decision making process. According to system approach marketing decision making process is seen as a set of related subprocesses. Provided an opportunity to use the economic and mathematical modelling at each stage of the decision making process.
STRONG NORMALIZATION IN TYPE SYSTEMS - A MODEL THEORETICAL APPROACH
TERLOUW, J
1995-01-01
Tait's proof of strong normalization for the simply typed lambda-calculus is interpreted in a general model theoretical framework by means of the specification of a certain theory T and a certain model U of T. The argumentation is partly reduced to formal predicate logic by the application of
Bioprinting towards Physiologically Relevant Tissue Models for Pharmaceutics.
Peng, Weijie; Unutmaz, Derya; Ozbolat, Ibrahim T
2016-09-01
Improving the ability to predict the efficacy and toxicity of drug candidates earlier in the drug discovery process will speed up the introduction of new drugs into clinics. 3D in vitro systems have significantly advanced the drug screening process as 3D tissue models can closely mimic native tissues and, in some cases, the physiological response to drugs. Among various in vitro systems, bioprinting is a highly promising technology possessing several advantages such as tailored microarchitecture, high-throughput capability, coculture ability, and low risk of cross-contamination. In this opinion article, we discuss the currently available tissue models in pharmaceutics along with their limitations and highlight the possibilities of bioprinting physiologically relevant tissue models, which hold great potential in drug testing, high-throughput screening, and disease modeling.
Fiberglass-reinforced glulam beams: mechanical properties and theoretical model
Juliano Fiorelli
2006-09-01
Full Text Available The glued-laminated lumber (glulam technique is an efficient process for making rational use of wood. Fiber-Reinforced Polymers (FRPs associated with glulam beams provide significant gains in terms of strength and stiffness, and also alter the mode of rupture of these structural elements. In this context, this paper presents a theoretical model for designing reinforced glulam beams. The model allows for the calculation of the bending moment, the hypothetical distribution of linear strains along the height of the beam, and considers the wood has a linear elastic fragile behavior in tension parallel to the fibers and bilinear in compression parallel to the fibers, initially elastic and subsequently inelastic, with a negative decline in the stress-strain diagram. The stiffness was calculated by the transformed section method. Twelve non-reinforced and fiberglass reinforced glulam beams were evaluated experimentally to validate the proposed theoretical model. The results obtained indicate good congruence between the experimental and theoretical values.
Yun Chen; Hui Yang
2016-01-01
In the era of big data, there are increasing interests on clustering variables for the minimization of data redundancy and the maximization of variable relevancy. Existing clustering methods, however, depend on nontrivial assumptions about the data structure. Note that nonlinear interdependence among variables poses significant challenges on the traditional framework of predictive modeling. In the present work, we reformulate the problem of variable clustering from an information theoretic pe...
Modelling Opinion Dynamics: Theoretical analysis and continuous approximation
Pinasco, Juan Pablo; Balenzuela, Pablo
2016-01-01
Frequently we revise our first opinions after talking over with other individuals because we get convinced. Argumentation is a verbal and social process aimed at convincing. It includes conversation and persuasion. In this case, the agreement is reached because the new arguments are incorporated. In this paper we deal with a simple model of opinion formation with such persuasion dynamics, and we find the exact analytical solutions for both, long and short range interactions. A novel theoretical approach has been used in order to solve the master equations of the model with non-local kernels. Simulation results demonstrate an excellent agreement with results obtained by the theoretical estimation.
A New Theoretical Model of a Carbon Nanotube Strain Sensor
QIU Wei; KANG Yi-Lan; LEI Zhen-Kun; QIN Qing-Hua; LI Qiu
2009-01-01
Carbon nanotubes (CNTs) are potential strain sensors due to their excellent mechanical and spectral properties.A new theoretical model of a CNT strain sensor is obtained by applying the polarized Raman properties of CNTs,which calculates the synthetic contributions of Raman spectra from the CNTs in random directions.By using this theoretical model,the analytic relationship between planar strain components and the Raman shift increment of uniformly dispersed CNTs is obtained,which is applicable for accurately characterizing the strain in random directions on the surface of a measured microsystem.
T. Thorvaldsen
2015-01-01
Full Text Available Mathematical models are investigated and suggested for the calculation of the elastic stiffness of polymer nanocomposites. Particular emphasis is placed on the effect on the elastic stiffness from agglomerates and the particle interphase properties. The multiphase Mori-Tanaka model and an interphase model are considered as two relevant models. These models only include and require the designation of a few system independent parameters with a clear physical meaning. Extensions of the models are also presented. The model calculations are compared to results from other models, as well as experimental data for different nanocomposites. For nanocomposites with spherical particles and with fiber-like particles, the suggested models are found to be the most flexible ones and are applicable to estimate the stiffness increase of nanocomposites for both low and high particle volume fractions. The suggested theoretical models can hence be considered as a general multiscale “model toolbox” for analysis of various nanocomposites.
Theoretical models in the development of advertising for food products
Bech-Larsen, Tino; Stacey, Julia
2005-01-01
Many advertising people believe that theoretical models hamper creativity and efficiency in the development of advertising messages. This need not be the case, if the theoretical models are sufficiently flexible and intelligible. On the contrary, a workable model that describes how...... the advertisement influences the target may serve as creative inspiration and as a common frame of reference for those involved in the development of advertisements. The means-end-chain model says that an advertisement is effective by connecting the product's attributes (means) and the target's personal values...... (ends). MAPP's experience with the model indicates that it is both flexible and intuitively accessible to practicians. In order to study this MAPP and the Danish Fruit Growers' Association asked an advertising agency to produce two campaign proposals with the purpose of getting young people to eat more...
Comparing the ecological relevance of four wave exposure models
Sundblad, G.; Bekkby, T.; Isæus, M.; Nikolopoulos, A.; Norderhaug, K. M.; Rinde, E.
2014-03-01
Wave exposure is one of the main structuring forces in the marine environment. Methods that enable large scale quantification of environmental variables have become increasingly important for predicting marine communities in the context of spatial planning and coastal zone management. Existing methods range from cartographic solutions to numerical hydrodynamic simulations, and differ in the scale and spatial coverage of their outputs. Using a biological exposure index we compared the performance of four wave exposure models ranging from simple to more advanced techniques. All models were found to be related to the biological exposure index and their performance, measured as bootstrapped R2 distributions, overlapped. Qualitatively, there were differences in the spatial patterns indicating higher complexity with more advanced techniques. In order to create complex spatial patterns wave exposure models should include diffraction, especially in coastal areas rich in islands. The inclusion of wind strength and frequency, in addition to wind direction and bathymetry, further tended to increase the amount of explained variation. The large potential of high-resolution numerical models to explain the observed patterns of species distribution in complex coastal areas provide exciting opportunities for future research. Easy access to relevant wave exposure models will aid large scale habitat classification systems and the continuously growing field of marine species distribution modelling, ultimately serving marine spatial management and planning.
Healing from Childhood Sexual Abuse: A Theoretical Model
Draucker, Claire Burke; Martsolf, Donna S.; Roller, Cynthia; Knapik, Gregory; Ross, Ratchneewan; Stidham, Andrea Warner
2011-01-01
Childhood sexual abuse is a prevalent social and health care problem. The processes by which individuals heal from childhood sexual abuse are not clearly understood. The purpose of this study was to develop a theoretical model to describe how adults heal from childhood sexual abuse. Community recruitment for an ongoing broader project on sexual…
THE THEORETICAL MODEL FOR PREDICTING CIRCULATION VELOCITY OF HYDRAULIC BRAKE
刘英林; 侯春生
1997-01-01
By rational hypothesis of fluid flow pattern, applied the law of conservation of energy and integrated the laboratory test results, finished the prediction by the theoretical model of circulation velocity of hydraulic brake which is important parameter. Thus provide the theoritical basis for hydraulic brake of belt conveyor whose research has just been started.
Organizational Learning and Product Design Management: Towards a Theoretical Model.
Chiva-Gomez, Ricardo; Camison-Zornoza, Cesar; Lapiedra-Alcami, Rafael
2003-01-01
Case studies of four Spanish ceramics companies were used to construct a theoretical model of 14 factors essential to organizational learning. One set of factors is related to the conceptual-analytical phase of the product design process and the other to the creative-technical phase. All factors contributed to efficient product design management…
THEORETICAL CHEMICAL ENGINEERING - Modeling and Simulation by Christo Boyadjiev
Simeon Oka
2010-01-01
Full Text Available Book Title: THEORETICAL CHEMICAL ENGINEERING - Modeling and Simulation Author(s: Christo Boyadjiev Institute of Chemical Engineering, Bulgarian Academy of Science, Sofia Publisher: Springer, 2010 ISBN: 978-3-642-10777-1 Review by: Prof. Simeon Oka, Ph. D., Scientific advisor - retired
THEORETICAL MODEL OF VIBRATING OBJECT TRANSMITTING NOISE TOWARDS EXTERNAL SOUND
姚志远
2002-01-01
On the basic theory of modal method, the coupling relation between the vibration of objects and external sound was analyzed, the theoretical model solving the vibration and noise was provided, the corresponding calculation formula was given. The calculating results show out that this calculation formula is correct.
Game-theoretic model of dispersed material drying process
Oleg, Malafeyev; Denis, Rylow; Irina, Zaitseva; Pavel, Zelenkovskii; Marina, Popova; Lydia, Novozhilova
2017-07-01
Continuous and discrete game-theoretic models of dispersed material drying process are formalized and studied in the paper. The existence of optimal drying strategies is shown through application of results from the theory of differential games and dynamic programming. These optimal strategies can be found numerically.
Organizational Resilience: The Theoretical Model and Research Implication
Xiao Lei
2017-01-01
Full Text Available Organizations are all subject to a diverse and ever changing and uncertain environment. Under this situation organizations should develop a capability which can resist the emergency and recover from the disruption. Base on lot of literature, the paper provides the main concept of organizational resilience; construct the primary theoretical model and some implications for management.
The Theoretical Foundation for Intercultural Business Communication: A Conceptual Model.
Varner, Iris I.
2000-01-01
Develops a theoretical framework for intercultural business communication which sets it apart from intercultural communication and international business. Presents a model that discusses the intercultural, business, and communication strategies that are part of intercultural business communication. Examines how past articles in the field fit into…
Healing from Childhood Sexual Abuse: A Theoretical Model
Draucker, Claire Burke; Martsolf, Donna S.; Roller, Cynthia; Knapik, Gregory; Ross, Ratchneewan; Stidham, Andrea Warner
2011-01-01
Childhood sexual abuse is a prevalent social and health care problem. The processes by which individuals heal from childhood sexual abuse are not clearly understood. The purpose of this study was to develop a theoretical model to describe how adults heal from childhood sexual abuse. Community recruitment for an ongoing broader project on sexual…
Fractional Moment Bounds and Disorder Relevance for Pinning Models
Derrida, Bernard; Giacomin, Giambattista; Lacoin, Hubert; Toninelli, Fabio Lucio
2009-05-01
We study the critical point of directed pinning/wetting models with quenched disorder. The distribution K(·) of the location of the first contact of the (free) polymer with the defect line is assumed to be of the form K( n) = n - α-1 L( n), with α ≥ 0 and L(·) slowly varying. The model undergoes a (de)-localization phase transition: the free energy (per unit length) is zero in the delocalized phase and positive in the localized phase. For α 1, then quenched and annealed critical points differ whenever disorder is present, and we give the scaling form of their difference for small disorder. In agreement with the so-called Harris criterion, disorder is therefore relevant in this case. In the marginal case α = 1/2, under the assumption that L(·) vanishes sufficiently fast at infinity, we prove that the difference between quenched and annealed critical points, which is smaller than any power of the disorder strength, is positive: disorder is marginally relevant. Again, the case considered in [12,17] is out of our analysis and remains open. The results are achieved by setting the parameters of the model so that the annealed system is localized, but close to criticality, and by first considering a quenched system of size that does not exceed the correlation length of the annealed model. In such a regime we can show that the expectation of the partition function raised to a suitably chosen power {γ in (0, 1)} is small. We then exploit such an information to prove that the expectation of the same fractional power of the partition function goes to zero with the size of the system, a fact that immediately entails that the quenched system is delocalized.
Are animal models relevant to key aspects of human parturition?
Mitchell, Bryan F; Taggart, Michael J
2009-09-01
Preterm birth remains the most serious complication of pregnancy and is associated with increased rates of infant death or permanent neurodevelopmental disability. Our understanding of the regulation of parturition remains inadequate. The scientific literature, largely derived from rodent animal models, suggests two major mechanisms regulating the timing of parturition: the withdrawal of the steroid hormone progesterone and a proinflammatory response by the immune system. However, available evidence strongly suggests that parturition in the human has significantly different regulators and mediators from those in most of the animal models. Our objectives are to critically review the data and concepts that have arisen from use of animal models for parturition and to rationalize the use of a new model. Many animal models have contributed to advances in our understanding of the regulation of parturition. However, we suggest that those animals dependent on progesterone withdrawal to initiate parturition clearly have a limitation to their translation to the human. In such models, a linear sequence of events (e.g., luteolysis, progesterone withdrawal, uterine activation, parturition) gives rise to the concept of a "trigger" mechanism. Conversely, we propose that human parturition may arise from the concomitant maturation of several systems in parallel. We have termed this novel concept "modular accumulation of physiological systems" (MAPS). We also emphasize the urgency to determine the precise role of the immune system in the process of parturition in situations other than intrauterine infection. Finally, we accentuate the need to develop a nonprimate animal model whose physiology is more relevant to human parturition. We suggest that the guinea pig displays several key physiological characteristics of gestation that more closely resemble human pregnancy than do currently favored animal models. We conclude that the application of novel concepts and new models are
Theoretical and Empirical Review of Asset Pricing Models: A Structural Synthesis
Saban Celik
2012-01-01
Full Text Available The purpose of this paper is to give a comprehensive theoretical review devoted to asset pricing models by emphasizing static and dynamic versions in the line with their empirical investigations. A considerable amount of financial economics literature devoted to the concept of asset pricing and their implications. The main task of asset pricing model can be seen as the way to evaluate the present value of the pay offs or cash flows discounted for risk and time lags. The difficulty coming from discounting process is that the relevant factors that affect the pay offs vary through the time whereas the theoretical framework is still useful to incorporate the changing factors into an asset pricing models. This paper fills the gap in literature by giving a comprehensive review of the models and evaluating the historical stream of empirical investigations in the form of structural empirical review.
A sigma model field theoretic realization of Hitchin's generalized complex geometry
Zucchini, Roberto [Dipartimento di Fisica, Universita degli Studi di Bologna, V. Irnerio 46, I-40126 Bologna (Italy); I.N.F.N., sezione di Bologna (Italy)]. E-mail: zucchinir@bo.infn.it
2004-11-01
We present a sigma model field theoretic realization of Hitchin's generalized complex geometry, which recently has been shown to be relevant in compactifications of superstring theory with fluxes. Hitchin sigma model is closely related to the well known Poisson sigma model, of which it has the same field content. The construction shows a remarkable correspondence between the (twisted) integrability conditions of generalized almost complex structures and the restrictions on target space geometry implied by the Batalin-Vilkovisky classical master equation. Further, the (twisted) classical Batalin-Vilkovisky cohomology is related non trivially to a generalized Dolbeault cohomology. (author)
A sigma model field theoretic realization of Hitchin's generalized complex geometry
Zucchini, R
2004-01-01
We present a sigma model field theoretic realization of Hitchin's generalized complex geometry, which recently has been shown to be relevant in compactifications of superstring theory with fluxes. Hitchin sigma model is closely related to the well known Poisson sigma model, of which it has the same field content. The construction shows a remarkable correspondence between the (twisted) integrability conditions of generalized almost complex structures and the restrictions on target space geometry implied by the Batalin--Vilkovisky classical master equation. Further, the (twisted) classical Batalin--Vilkovisky cohomology is related non trivially to a generalized Dolbeault cohomology.
Model selection and inference a practical information-theoretic approach
Burnham, Kenneth P
1998-01-01
This book is unique in that it covers the philosophy of model-based data analysis and an omnibus strategy for the analysis of empirical data The book introduces information theoretic approaches and focuses critical attention on a priori modeling and the selection of a good approximating model that best represents the inference supported by the data Kullback-Leibler information represents a fundamental quantity in science and is Hirotugu Akaike's basis for model selection The maximized log-likelihood function can be bias-corrected to provide an estimate of expected, relative Kullback-Leibler information This leads to Akaike's Information Criterion (AIC) and various extensions and these are relatively simple and easy to use in practice, but little taught in statistics classes and far less understood in the applied sciences than should be the case The information theoretic approaches provide a unified and rigorous theory, an extension of likelihood theory, an important application of information theory, and are ...
Pereira, J.; Montes, F.
2016-03-01
Background: Neutrino-driven winds following core-collapse supernova explosions have been proposed as a possible site where light r -process nuclei (between Fe and Ag) might be synthesized. In these events, (α ,n ) reactions are key to moving matter towards the region of higher proton number. Abundance network calculations are very sensitive to the rates for this type of reactions. Purpose: The present work aims at evaluating the theoretical uncertainty of these (α ,n ) reactions calculated with reaction codes based on the Hauser-Feshbach model. Method: We compared several (α ,n ) rates taken from talys and the non-smoker database to determine the uncertainties owing to the existing technical differences between both codes. In addition, we evaluated the sensitivity of talys rates to variations in the α optical potentials, masses, level densities, optical potentials, preequilibrium intranuclear transition rates, level structure, radiative transmission coefficients, and width-fluctuation correction factors. Results: The main source of uncertainty at low temperature is mostly attributable to the use of different α optical potentials. Differences between talys and non-smoker at high temperatures arise from the energy-binning algorithm used by each code. We have also noticed that the (α ,n ) rates from the non-smoker database correspond to the inclusive reaction, instead of the exclusive (α ,1 n ) channel calculated in the present work and used in network calculations. Conclusions: Theoretical uncertainties in calculated reaction rates can be as high as one to two orders of magnitude and strongly dependent on the temperature of the environment. Besides direct measurements of the inclusive and exclusive (α ,1 n ) reaction rates, experimental studies of α optical potentials are crucial to improve the performance of reaction codes.
A theoretical model for smoking prevention studies in preteen children.
McGahee, T W; Kemp, V; Tingen, M
2000-01-01
The age of the onset of smoking is on a continual decline, with the prime age of tobacco use initiation being 12-14 years. A weakness of the limited research conducted on smoking prevention programs designed for preteen children (ages 10-12) is a well-defined theoretical basis. A theoretical perspective is needed in order to make a meaningful transition from empirical analysis to application of knowledge. Bandura's Social Cognitive Theory (1977, 1986), the Theory of Reasoned Action (Ajzen & Fishbein, 1980), and other literature linking various concepts to smoking behaviors in preteens were used to develop a model that may be useful for smoking prevention studies in preteen children.
Theoretic computing model of combustion process of asphalt smoke
HUANG Rui; CHAI Li-yuan; HE De-wen; PENG Bing; WANG Yun-yan
2005-01-01
Based on the data and methods provided by research literature, dispersing mathematical model of combustion process of asphalt smoke is set by theoretic analysis. Through computer programming, the dynamic combustion process of asphalt smoke is calculated to simulate an experimental model. The computing result shows that the temperature and the concentration of asphalt smoke influence its burning temperature in approximatively linear manner. The consumed quantity of fuel to ignite the asphalt smoke needs to be measured from the two factors.
A Modified Theoretical Model of Intrinsic Hardness of Crystalline Solids
Fu-Zhi Dai; Yanchun Zhou
2016-01-01
Super-hard materials have been extensively investigated due to their practical importance in numerous industrial applications. To stimulate the design and exploration of new super-hard materials, microscopic models that elucidate the fundamental factors controlling hardness are desirable. The present work modified the theoretical model of intrinsic hardness proposed by Gao. In the modification, we emphasize the critical role of appropriately decomposing a crystal to pseudo-binary crystals, wh...
Electromechanical properties of smart aggregate: theoretical modeling and experimental validation
Wang, Jianjun; Kong, Qingzhao; Shi, Zhifei; Song, Gangbing
2016-09-01
Smart aggregate (SA), as a piezoceramic-based multi-functional device, is formed by sandwiching two lead zirconate titanate (PZT) patches with copper shielding between a pair of solid-machined cylindrical marble blocks with epoxy. Previous researches have successfully demonstrated the capability and reliability of versatile SAs to monitor the structural health of concrete structures. However, the previous works concentrated mainly on the applications of SAs in structural health monitoring; no reasonable theoretical model of SAs was proposed. In this paper, electromechanical properties of SAs were investigated using a proposed theoretical model. Based on one dimensional linear theory of piezo-elasticity, the dynamic solutions of a SA subjected to an external harmonic voltage were solved. Further, the electric impedance of the SA was computed, and the resonance and anti-resonance frequencies were calculated based on derived equations. Numerical analysis was conducted to discuss the effects of the thickness of epoxy layer and the dimension of PZT patch on the fundamental resonance and anti-resonance frequencies as well as the corresponding electromechanical coupling factor. The dynamic solutions based on the proposed theoretical model were further experimentally verified with two SA samples. The fundamental resonance and anti-resonance frequencies of SAs show good agreements in both theoretical and experimental results. The presented analysis and results contribute to the overall understanding of SA properties and help to optimize the working frequencies of SAs in structural health monitoring of civil structures.
Examination of a Theoretical Model of Streaming Potential Coupling Coefficient
D. T. Luong
2014-01-01
Full Text Available Seismoelectric effects and streaming potentials play an important role in geophysical applications. The key parameter for those phenomena is the streaming potential coupling coefficient, which is, for example, dependent on the zeta potential of the interface of the porous rocks. Comparison of an existing theoretical model to experimental data sets from available published data for streaming potentials has been performed. However, the existing experimental data sets are based on samples with dissimilar fluid conductivity, pH of pore fluid, temperature, and sample compositions. All those dissimilarities may cause the observed deviations. To critically assess the models, we have carried out streaming potential measurement as a function of electrolyte concentration and temperature for a set of well-defined consolidated samples. The results show that the existing theoretical model is not in good agreement with the experimental observations when varying the electrolyte concentration, especially at low electrolyte concentration. However, if we use a modified model in which the zeta potential is considered to be constant over the electrolyte concentration, the model fits the experimental data well in a whole range of concentration. Also, for temperature dependence, the comparison shows that the theoretical model is not fully adequate to describe the experimental data but does describe correctly the increasing trend of the coupling coefficient as function of temperature.
Inclusion of Relevance Information in the Term Discrimination Model.
Biru, Tesfaye; And Others
1989-01-01
Discusses the effect of including relevance data on the calculation of term discrimination values in bibliographic databases. Algorithms that calculate the ability of index terms to discriminate between relevant and non-relevant documents are described and tested. The results are discussed in terms of the relationship between term frequency and…
Location Criteria Relevant for Sustainability of Social Housing Model
Petković-Grozdanović Nataša
2016-01-01
Full Text Available Social housing models, which had began to develop during the last century, for their only objective had a need to overcome the housing problems of socially vulnerable categories. However, numerous studies have shown that these social categories, because of their low social status, are highly susceptible to various psychological and sociological problems. On the other hand a low level of quality, which was common for social housing dwellings, has further aggravated these problems by initiating trouble behaviours among tenants, affecting social exclusion and segregation. Contemporary social housing models are therefore conceptualized in a way to provide a positive psycho-sociological impact on their tenants. Therefore the planning approach in social housing should be such to: support important functions in daily life routines; promote tolerance and cooperation; influence on a sense of social order and belonging; affect the socialization of the tenant and their integration into the wider community; and improve social cohesion. Analysis of the influential location parameters of immediate and wider social housing environment strive to define the ones relevant to the life quality of social housing tenants and therefore influence on the sustainability of social housing model.
Multiscale modeling of complex materials phenomenological, theoretical and computational aspects
Trovalusci, Patrizia
2014-01-01
The papers in this volume deal with materials science, theoretical mechanics and experimental and computational techniques at multiple scales, providing a sound base and a framework for many applications which are hitherto treated in a phenomenological sense. The basic principles are formulated of multiscale modeling strategies towards modern complex multiphase materials subjected to various types of mechanical, thermal loadings and environmental effects. The focus is on problems where mechanics is highly coupled with other concurrent physical phenomena. Attention is also focused on the historical origins of multiscale modeling and foundations of continuum mechanics currently adopted to model non-classical continua with substructure, for which internal length scales play a crucial role.
A General Theoretical Model of Enthalpy-EntropyCompensation
LIU，Lei; GUO, Qing-Xiang
2001-01-01
Enthalpy-entropy compensation remains a mystery in chemistry and biophysics.recent study suggested that the solventreorganization might constitute the physical orihin of the compensation, which was unforumstely not wisely applicable because compensation was also observeserved in solid phade reactions.In this study,a general theoretical model based upon strictmathematical deduction was presented,which indicated thatthe redistribution of the distinguishable subspecies might bethe physical origin of the enthalpy-intropy compensations in solvation and surface adsorption weue discussed.
A theoretical retention model for unsaturated uniform and graded soils
Monnet Jacques
2016-01-01
Full Text Available Modelling the relation between the degree of saturation and the suction (ie retention curve is an important challenge for geotechnical engineering. It has a huge influence on the behavior of large soil constructions as levees, embankments, road earthworks. We present here a theoretical model of retention curve which considers physical relations of unsaturated soils. With this approach, there is no need to assume particular shapes of the retention curves, which are a consequence of the physical assumptions. The present study is focused on a theoretical model based on elastic spherical particle arrangement. As a first step a uniform model is presented with a single diameter of soil particle. A second step extends the use of the model to graded soils. The model uses only 5 physical parameters. It is compared with the experimental retention curve of two different samples of glass uniform particles and two different graded soils, a graded glass sample and the Livet-Gavet loam. It shows its ability to model the experimental curves and a better agreement than the former theory of Brooks and Corey (1966. This current publication is funded by the French National Project «Terredurable» (ANR 2011,.
A Theoretical Framework for Physics Education Research: Modeling Student Thinking
Redish, E F
2004-01-01
Education is a goal-oriented field. But if we want to treat education scientifically so we can accumulate, evaluate, and refine what we learn, then we must develop a theoretical framework that is strongly rooted in objective observations and through which different theoretical models of student thinking can be compared. Much that is known in the behavioral sciences is robust and observationally based. In this paper, I draw from a variety of fields ranging from neuroscience to sociolinguistics to propose an over-arching theoretical framework that allows us to both make sense of what we see in the classroom and to compare a variety of specific theoretical approaches. My synthesis is organized around an analysis of the individual's cognition and how it interacts with the environment. This leads to a two level system, a knowledge-structure level where associational patterns dominate, and a control-structure level where one can describe expectations and epistemology. For each level, I sketch some plausible startin...
Application of a theoretical model to evaluate COPD disease management.
Lemmens, Karin M M; Nieboer, Anna P; Rutten-Van Mölken, Maureen P M H; van Schayck, Constant P; Asin, Javier D; Dirven, Jos A M; Huijsman, Robbert
2010-03-26
Disease management programmes are heterogeneous in nature and often lack a theoretical basis. An evaluation model has been developed in which theoretically driven inquiries link disease management interventions to outcomes. The aim of this study is to methodically evaluate the impact of a disease management programme for patients with chronic obstructive pulmonary disease (COPD) on process, intermediate and final outcomes of care in a general practice setting. A quasi-experimental research was performed with 12-months follow-up of 189 COPD patients in primary care in the Netherlands. The programme included patient education, protocolised assessment and treatment of COPD, structural follow-up and coordination by practice nurses at 3, 6 and 12 months. Data on intermediate outcomes (knowledge, psychosocial mediators, self-efficacy and behaviour) and final outcomes (dyspnoea, quality of life, measured by the CRQ and CCQ, and patient experiences) were obtained from questionnaires and electronic registries. Implementation of the programme was associated with significant improvements in dyspnoea (p model showed associations between significantly improved intermediate outcomes and improvements in quality of life and dyspnoea. The application of a theory-driven model enhances the design and evaluation of disease management programmes aimed at improving health outcomes. This study supports the notion that a theoretical approach strengthens the evaluation designs of complex interventions. Moreover, it provides prudent evidence that the implementation of COPD disease management programmes can positively influence outcomes of care.
Dirba, I.; Kleperis, J.
2011-01-01
Analytical and numerical modelling is performed for the linear actuator of a parallel path magnet motor. In the model based on finite-element analysis, the 3D problem is reduced to a 2D problem, which is sufficiently precise in a design aspect and allows modelling the principle of a parallel path motor. The paper also describes a relevant numerical model and gives comparison with experimental results. The numerical model includes all geometrical and physical characteristics of the motor components. The magnetic flux density and magnetic force are simulated using FEMM 4.2 software. An experimental model has also been developed and verified for the core of switchable magnetic flux linear actuator and motor. The results of experiments are compared with those of theoretical/analytical and numerical modelling.
Exploring female mice interstrain differences relevant for models of depression
Daniela de Sá Calçada
2015-12-01
Full Text Available Depression is an extremely heterogeneous disorder. Diverse molecular mechanisms have been suggested to underlie its etiology. To understand the molecular mechanisms responsible for this complex disorder, researchers have been using animal models extensively, namely mice from various genetic backgrounds and harboring distinct genetic modifications. The use of numerous mouse models has contributed to enrich our knowledge on depression. However, accumulating data also revealed that the intrinsic characteristics of each mouse strain might influence the experimental outcomes, which may justify some conflicting evidence reported in the literature. To further understand the impact of the genetic background we performed a multimodal comparative study encompassing the most relevant parameters commonly addressed in depression in three of the most widely used mouse strains: Balb/c, C57BL/6 and CD-1. Moreover, female mice were selected for this study taken into account the higher prevalence of depression in woman and the fewer animal studies using this gender. Our results show that Balb/c mice have a more pronounced anxious-like behavior than CD-1 and C57BL/6 mice, whereas C57BL/6 animals present the strongest depressive-like trait. Furthermore, C57BL/6 mice display the highest rate of proliferating cells and brain-derived neurotrophic factor expression levels in the hippocampus, while hippocampal dentate granular neurons of Balb/c mice show smaller dendritic lengths and fewer ramifications. Of notice, the expression levels of inducible nitric oxide synthase (iNos predict 39,5% of the depressive-like behavior index, which suggests a key role of hippocampal iNOS in depression.Overall, this study reveals important interstrain differences in several behavioral dimensions and molecular and cellular parameters that should be considered when preparing and analyzing experiments addressing depression using mouse models. It further contributes to the literature by
Information Theoretic Tools for Parameter Fitting in Coarse Grained Models
Kalligiannaki, Evangelia
2015-01-07
We study the application of information theoretic tools for model reduction in the case of systems driven by stochastic dynamics out of equilibrium. The model/dimension reduction is considered by proposing parametrized coarse grained dynamics and finding the optimal parameter set for which the relative entropy rate with respect to the atomistic dynamics is minimized. The minimization problem leads to a generalization of the force matching methods to non equilibrium systems. A multiplicative noise example reveals the importance of the diffusion coefficient in the optimization problem.
A theoretical model of multi-agent quantum computing
Mihelic, F. Matthew
2011-05-01
The best design for practical quantum computing is one that emulates the multi-agent quantum logic function of natural biological systems. Such systems are theorized to be based upon a quantum gate formed by a nucleic acid Szilard engine (NASE) that converts Shannon entropy of encountered molecules into useful work of nucleic acid geometric reconfiguration. This theoretical mechanism is logically and thermodynamically reversible in this special case because it is literally constructed out of the (nucleic acid) information necessary for its function, thereby allowing the nucleic acid Szilard engine to function reversibly because, since the information by which it functions exists on both sides of the theoretical mechanism simultaneously, there would be no build-up of information within the theoretical mechanism, and therefore no irreversible thermodynamic energy cost would be necessary to erase information inside the mechanism. This symmetry breaking Szilard engine function is associated with emission and/or absorption of entangled photons that can provide quantum synchronization of other nucleic acid segments within and between cells. In this manner nucleic acids can be considered as a natural model of topological quantum computing in which the nonabelian interaction of genes can be represented within quantum knot/braid theory as anyon crosses determined by entropic loss or gain that leads to changes in nucleic acid covalent bond angles. This naturally occurring biological form of topological quantum computing can serve as a model for workable man-made multi-agent quantum computing systems.
Application of a theoretical model to evaluate COPD disease management
Asin Javier D
2010-03-01
Full Text Available Abstract Background Disease management programmes are heterogeneous in nature and often lack a theoretical basis. An evaluation model has been developed in which theoretically driven inquiries link disease management interventions to outcomes. The aim of this study is to methodically evaluate the impact of a disease management programme for patients with chronic obstructive pulmonary disease (COPD on process, intermediate and final outcomes of care in a general practice setting. Methods A quasi-experimental research was performed with 12-months follow-up of 189 COPD patients in primary care in the Netherlands. The programme included patient education, protocolised assessment and treatment of COPD, structural follow-up and coordination by practice nurses at 3, 6 and 12 months. Data on intermediate outcomes (knowledge, psychosocial mediators, self-efficacy and behaviour and final outcomes (dyspnoea, quality of life, measured by the CRQ and CCQ, and patient experiences were obtained from questionnaires and electronic registries. Results Implementation of the programme was associated with significant improvements in dyspnoea (p Conclusions The application of a theory-driven model enhances the design and evaluation of disease management programmes aimed at improving health outcomes. This study supports the notion that a theoretical approach strengthens the evaluation designs of complex interventions. Moreover, it provides prudent evidence that the implementation of COPD disease management programmes can positively influence outcomes of care.
Polarisers in the focal domain: Theoretical model and experimental validation
Martínez-Herrero, Rosario; Maluenda, David; Juvells, Ignasi; Carnicer, Artur
2017-02-01
Polarisers are one of the most widely used devices in optical set-ups. They are commonly used with paraxial beams that propagate in the normal direction of the polariser plane. Nevertheless, the conventional projection character of these devices may change when the beam impinges a polariser with a certain angle of incidence. This effect is more noticeable if polarisers are used in optical systems with a high numerical aperture, because multiple angles of incidence have to be taken into account. Moreover, the non-transverse character of highly focused beams makes the problem more complex and strictly speaking, the Malus’ law does not apply. In this paper we develop a theoretical framework to explain how ideal polarisers affect the behavior of highly focused fields. In this model, the polarisers are considered as birefringent plates, and the vector behaviour of focused fields is described using the plane-wave angular spectrum approach. Experiments involving focused fields were conducted to verify the theoretical model and a satisfactory agreement between theoretical and experimental results was found.
The truncation of stellar discs A theoretical model
Battaner, E; Jiménez-Vicente, J
1998-01-01
The truncation of stellar discs is not abrupt but characterized by a continuous distancing from the exponential profile. There exists a truncation curve, $t(r)$, ending at a truncation radius, $r_t$. We present here a theoretical model in which it is assumed that the magnetic hypothesis explaining the flat rotation curve also explains the truncation. Once stars are born, the centripetal magnetic force previously acting on the progenitor gas cloud is suddenly interrupted, and stars must move to larger orbits or escape. The agreement between theoretical and observed truncation curves is very satisfactory. Parameters defining the disc gas rotation curve should therefore be related to those defining the truncation. It is predicted that rotation curves that quickly reach the asymptotic value $\\theta_0 = \\theta (r=\\infty)$ would have small truncation radii. On the contrary, $r_t$ and $\\theta_0$ itself, would be uncorrelated quantities.
Relevant parameters in models of cell division control
Grilli, Jacopo; Kennard, Andrew S; Lagomarsino, Marco Cosentino
2016-01-01
A recent burst of dynamic single-cell growth-division data makes it possible to characterize the stochastic dynamics of cell division control in bacteria. Different modeling frameworks were used to infer specific mechanisms from such data, but the links between frameworks are poorly explored, with relevant consequences for how well any particular mechanism can be supported by the data. Here, we describe a simple and generic framework in which two common formalisms can be used interchangeably: (i) a continuous-time division process described by a hazard function and (ii) a discrete-time equation describing cell size across generations (where the unit of time is a cell cycle). In our framework, this second process is a discrete-time Langevin equation with a simple physical analogue. By perturbative expansion around the mean initial size (or inter-division time), we show explicitly how this framework describes a wide range of division control mechanisms, including combinations of time and size control, as well a...
A Modified Theoretical Model of Intrinsic Hardness of Crystalline Solids
Dai, Fu-Zhi; Zhou, Yanchun
2016-01-01
Super-hard materials have been extensively investigated due to their practical importance in numerous industrial applications. To stimulate the design and exploration of new super-hard materials, microscopic models that elucidate the fundamental factors controlling hardness are desirable. The present work modified the theoretical model of intrinsic hardness proposed by Gao. In the modification, we emphasize the critical role of appropriately decomposing a crystal to pseudo-binary crystals, which should be carried out based on the valence electron population of each bond. After modification, the model becomes self-consistent and predicts well the hardness values of many crystals, including crystals composed of complex chemical bonds. The modified model provides fundamental insights into the nature of hardness, which can facilitate the quest for intrinsic super-hard materials. PMID:27604165
The creep experiment and theoretical model analysis of gascontaining coal
YIN Guang-zhi; ZHANG Dong-ming; WANG Wei-zhong
2007-01-01
A creep experiment of preformed molding coal under different confining pressures were carried out using self-developed 3-triaxial creep loading device for gas-containing coal, which loaded by Shimadzu AGI-250 kN electrical servo-controlled stiffness testing machine. Based on the experimental results, the variation trend of axial deformation under different stress states was studied, and creep failure characteristics of gascontaining coal under different confining pressures were analyzed. The experimental results were identified with seven-component nonlinear viscoelasto-plastic creep model (Hohai model), and the creep material parameters were obtained. The experimental result complies well with the theoretical value of this model. It indicates that creep constitutive relation of gas-containing coal can be expressed by nonlinear viscoelasto-plastic creep model correctly.
A Modified Theoretical Model of Intrinsic Hardness of Crystalline Solids
Dai, Fu-Zhi; Zhou, Yanchun
2016-09-01
Super-hard materials have been extensively investigated due to their practical importance in numerous industrial applications. To stimulate the design and exploration of new super-hard materials, microscopic models that elucidate the fundamental factors controlling hardness are desirable. The present work modified the theoretical model of intrinsic hardness proposed by Gao. In the modification, we emphasize the critical role of appropriately decomposing a crystal to pseudo-binary crystals, which should be carried out based on the valence electron population of each bond. After modification, the model becomes self-consistent and predicts well the hardness values of many crystals, including crystals composed of complex chemical bonds. The modified model provides fundamental insights into the nature of hardness, which can facilitate the quest for intrinsic super-hard materials.
A Modified Theoretical Model of Intrinsic Hardness of Crystalline Solids.
Dai, Fu-Zhi; Zhou, Yanchun
2016-09-08
Super-hard materials have been extensively investigated due to their practical importance in numerous industrial applications. To stimulate the design and exploration of new super-hard materials, microscopic models that elucidate the fundamental factors controlling hardness are desirable. The present work modified the theoretical model of intrinsic hardness proposed by Gao. In the modification, we emphasize the critical role of appropriately decomposing a crystal to pseudo-binary crystals, which should be carried out based on the valence electron population of each bond. After modification, the model becomes self-consistent and predicts well the hardness values of many crystals, including crystals composed of complex chemical bonds. The modified model provides fundamental insights into the nature of hardness, which can facilitate the quest for intrinsic super-hard materials.
A Game-Theoretic Model for Distributed Programming by Contract
Henriksen, Anders Starcke; Hvitved, Tom; Filinski, Andrzej
2009-01-01
We present an extension of the programming-by-contract (PBC) paradigm to a concurrent and distributed environment. Classical PBC is characterized by absolute conformance of code to its specification, assigning blame in case of failures, and a hierarchical, cooperative decomposition model – none...... of which extend naturally to a distributed environment with multiple administrative peers. We therefore propose a more nuanced contract model based on quantifiable performance of implementations; assuming responsibility for success; and a fundamentally adversarial model of system integration, where each...... component provider is optimizing its behavior locally, with respect to potentially conflicting demands. This model gives rise to a game-theoretic formulation of contract-governed process interactions that supports compositional reasoning about contract conformance....
Stability of theoretical model for catastrophic weather prediction
SHI Wei-hui; WANG Yue-peng
2007-01-01
Stability related to theoretical model for catastrophic weather prediction,which includes non-hydrostatic perfect elastic model and anelastic model, is discussed and analyzed in detail. It is proved that non-hydrostatic perfect elastic equations set is stable in the class of infinitely differentiable function. However, for the anelastic equations set, its continuity equation is changed in form because of the particular hypothesis for fluid, so "the matching consisting of both viscosity coefficient and incompressible assumption" appears, thereby the most important equations set of this class in practical prediction shows the same instability in topological property as Navier-Stokes equation,which should be avoided first in practical numerical prediction. In light of this, the referenced suggestions to amend the applied model are finally presented.
Comparing theoretical models of our galaxy with observations
Johnston K.V.
2012-02-01
Full Text Available With the advent of large scale observational surveys to map out the stars in our galaxy, there is a need for an efficient tool to compare theoretical models of our galaxy with observations. To this end, we describe here the code Galaxia, which uses efficient and fast algorithms for creating a synthetic survey of the Milky Way, and discuss its uses. Given one or more observational constraints like the color-magnitude bounds, a survey size and geometry, Galaxia returns a catalog of stars in accordance with a given theoretical model of the Milky Way. Both analytic and N-body models can be sampled by Galaxia. For N-body models, we present a scheme that disperses the stars spawned by an N-body particle, in such a way that the phase space density of the spawned stars is consistent with that of the N-body particles. The code is ideally suited to generating synthetic data sets that mimic near future wide area surveys such as GAIA, LSST and HERMES. In future, we plan to release the code publicly at http://galaxia.sourceforge.net. As an application of the code, we study the prospect of identifying structures in the stellar halo with future surveys that will have velocity information about the stars.
Theoretical consideration of a microcontinuum model of graphene
Gang Yang
2016-05-01
Full Text Available A microcontinuum model of graphene is proposed based on micromorphic theory, in which the planar Bravais cell of graphene crystal is taken as the basal element of finite size. Governing equations including the macro-displacements and the micro-deformations of the basal element are modified and derived in global coordinates. Since independent freedom degrees of the basal element are closely related to the modes of phonon dispersions, the secular equations in micromorphic form are obtained by substituting the assumed harmonic wave equations into the governing equations, and simplified further according to the properties of phonon dispersion relations of two-dimensional (2D crystals. Thus, the constitutive equations of the microcontinuum model are confirmed, in which the constitutive constants are determined by fitting the data of experimental and theoretical phonon dispersion relations in literature respectively. By employing the 2D microcontinuum model, we obtained sound velocities, Rayleigh velocity and elastic moduli of graphene, which show good agreements with available experimental or theoretical values, indicating that the current model would be another efficient and reliable methodology to study the mechanical behaviors of graphene.
Wenzl Tatiana
2011-12-01
Full Text Available Abstract Background The increased resistance of hypoxic cells to ionizing radiation is usually believed to be the primary reason for treatment failure in tumors with oxygen-deficient areas. This oxygen effect can be expressed quantitatively by the oxygen enhancement ratio (OER. Here we investigate theoretically the dependence of the OER on the applied local dose for different types of ionizing irradiation and discuss its importance for clinical applications in radiotherapy for two scenarios: small dose variations during hypoxia-based dose painting and larger dose changes introduced by altered fractionation schemes. Methods Using the widespread Alper-Howard-Flanders and standard linear-quadratic (LQ models, OER calculations are performed for T1 human kidney and V79 Chinese hamster cells for various dose levels and various hypoxic oxygen partial pressures (pO2 between 0.01 and 20 mmHg as present in clinical situations in vivo. Our work comprises the analysis for both low linear energy transfer (LET treatment with photons or protons and high-LET treatment with heavy ions. A detailed analysis of experimental data from the literature with respect to the dose dependence of the oxygen effect is performed, revealing controversial opinions whether the OER increases, decreases or stays constant with dose. Results The behavior of the OER with dose per fraction depends primarily on the ratios of the LQ parameters alpha and beta under hypoxic and aerobic conditions, which themselves depend on LET, pO2 and the cell or tissue type. According to our calculations, the OER variations with dose in vivo for low-LET treatments are moderate, with changes in the OER up to 11% for dose painting (1 or 3 Gy per fraction compared to 2 Gy and up to 22% in hyper-/hypofractionation (0.5 or 20 Gy per fraction compared to 2 Gy for oxygen tensions between 0.2 and 20 mmHg typically measured clinically in hypoxic tumors. For extremely hypoxic cells (0.01 mmHg, the dose dependence
Information-Theoretic Benchmarking of Land Surface Models
Nearing, Grey; Mocko, David; Kumar, Sujay; Peters-Lidard, Christa; Xia, Youlong
2016-04-01
Benchmarking is a type of model evaluation that compares model performance against a baseline metric that is derived, typically, from a different existing model. Statistical benchmarking was used to qualitatively show that land surface models do not fully utilize information in boundary conditions [1] several years before Gong et al [2] discovered the particular type of benchmark that makes it possible to *quantify* the amount of information lost by an incorrect or imperfect model structure. This theoretical development laid the foundation for a formal theory of model benchmarking [3]. We here extend that theory to separate uncertainty contributions from the three major components of dynamical systems models [4]: model structures, model parameters, and boundary conditions describe time-dependent details of each prediction scenario. The key to this new development is the use of large-sample [5] data sets that span multiple soil types, climates, and biomes, which allows us to segregate uncertainty due to parameters from the two other sources. The benefit of this approach for uncertainty quantification and segregation is that it does not rely on Bayesian priors (although it is strictly coherent with Bayes' theorem and with probability theory), and therefore the partitioning of uncertainty into different components is *not* dependent on any a priori assumptions. We apply this methodology to assess the information use efficiency of the four land surface models that comprise the North American Land Data Assimilation System (Noah, Mosaic, SAC-SMA, and VIC). Specifically, we looked at the ability of these models to estimate soil moisture and latent heat fluxes. We found that in the case of soil moisture, about 25% of net information loss was from boundary conditions, around 45% was from model parameters, and 30-40% was from the model structures. In the case of latent heat flux, boundary conditions contributed about 50% of net uncertainty, and model structures contributed
Relevant parameters in models of cell division control
Grilli, Jacopo; Osella, Matteo; Kennard, Andrew S.; Lagomarsino, Marco Cosentino
2017-03-01
A recent burst of dynamic single-cell data makes it possible to characterize the stochastic dynamics of cell division control in bacteria. Different models were used to propose specific mechanisms, but the links between them are poorly explored. The lack of comparative studies makes it difficult to appreciate how well any particular mechanism is supported by the data. Here, we describe a simple and generic framework in which two common formalisms can be used interchangeably: (i) a continuous-time division process described by a hazard function and (ii) a discrete-time equation describing cell size across generations (where the unit of time is a cell cycle). In our framework, this second process is a discrete-time Langevin equation with simple physical analogues. By perturbative expansion around the mean initial size (or interdivision time), we show how this framework describes a wide range of division control mechanisms, including combinations of time and size control, as well as the constant added size mechanism recently found to capture several aspects of the cell division behavior of different bacteria. As we show by analytical estimates and numerical simulations, the available data are described precisely by the first-order approximation of this expansion, i.e., by a "linear response" regime for the correction of size fluctuations. Hence, a single dimensionless parameter defines the strength and action of the division control against cell-to-cell variability (quantified by a single "noise" parameter). However, the same strength of linear response may emerge from several mechanisms, which are distinguished only by higher-order terms in the perturbative expansion. Our analytical estimate of the sample size needed to distinguish between second-order effects shows that this value is close to but larger than the values of the current datasets. These results provide a unified framework for future studies and clarify the relevant parameters at play in the control of
Improving statistical reasoning theoretical models and practical implications
Sedlmeier, Peter
1999-01-01
This book focuses on how statistical reasoning works and on training programs that can exploit people''s natural cognitive capabilities to improve their statistical reasoning. Training programs that take into account findings from evolutionary psychology and instructional theory are shown to have substantially larger effects that are more stable over time than previous training regimens. The theoretical implications are traced in a neural network model of human performance on statistical reasoning problems. This book apppeals to judgment and decision making researchers and other cognitive scientists, as well as to teachers of statistics and probabilistic reasoning.
Theoretical Models and Operational Frameworks in Public Health Ethics
Petrini, Carlo
2010-01-01
The article is divided into three sections: (i) an overview of the main ethical models in public health (theoretical foundations); (ii) a summary of several published frameworks for public health ethics (practical frameworks); and (iii) a few general remarks. Rather than maintaining the superiority of one position over the others, the main aim of the article is to summarize the basic approaches proposed thus far concerning the development of public health ethics by describing and comparing the various ideas in the literature. With this in mind, an extensive list of references is provided. PMID:20195441
Theoretical Models and Operational Frameworks in Public Health Ethics
Carlo Petrini
2010-01-01
Full Text Available The article is divided into three sections: (i an overview of the main ethical models in public health (theoretical foundations; (ii a summary of several published frameworks for public health ethics (practical frameworks; and (iii a few general remarks. Rather than maintaining the superiority of one position over the others, the main aim of the article is to summarize the basic approaches proposed thus far concerning the development of public health ethics by describing and comparing the various ideas in the literature. With this in mind, an extensive list of references is provided.
Information Theoretic Authentication and Secrecy Codes in the Splitting Model
Huber, Michael
2011-01-01
In the splitting model, information theoretic authentication codes allow non-deterministic encoding, that is, several messages can be used to communicate a particular plaintext. Certain applications require that the aspect of secrecy should hold simultaneously. Ogata-Kurosawa-Stinson-Saido (2004) have constructed optimal splitting authentication codes achieving perfect secrecy for the special case when the number of keys equals the number of messages. In this paper, we establish a construction method for optimal splitting authentication codes with perfect secrecy in the more general case when the number of keys may differ from the number of messages. To the best knowledge, this is the first result of this type.
A survey of game-theoretic models of cooperative advertising
Jørgensen, Steffen; Zaccour, G.
2014-01-01
The paper surveys the literature on cooperative advertising in marketing channels (supply chains) using game theoretic methods. During the last decade, in particular, this literature has expanded considerably and has studied static as well as dynamic settings. The survey is divided into two main...... environments. We also find that the work on static models is quite homogeneous, in the sense that most papers employ the same basic consumer demand specification and address the same situations of vertical integration and noncooperative games with simultaneous or sequential actions. The work on dynamic...
Experimental and theoretical models of human cultural evolution.
Kempe, Marius; Mesoudi, Alex
2014-05-01
The modern field of cultural evolution is now over 30 years old, and an extensive body of theory and data has been amassed. This article reviews models of cultural evolution, both experimental and theoretical, and surveys what they can tell us about cultural evolutionary processes. The models are grouped according to which of four broad questions they address: (1) How are cultural traits changed during transmission? (2) How and why do cultural traits accumulate over time? (3) What social learning biases do people use? and (4) What are the population-level consequences of different social learning biases? We conclude by highlighting gaps in the literature and promising future research directions, including the further integration of theoretical models and experimental data, the identification of the factors underlying cumulative cultural evolution, and the explanation of individual and cultural variation in social learning biases. For further resources related to this article, please visit the WIREs website. The authors have declared no conflicts of interest for this article. © 2014 John Wiley & Sons, Ltd.
Theoretical models for coronary vascular biomechanics: Progress & challenges
Waters, Sarah L.; Alastruey, Jordi; Beard, Daniel A.; Bovendeerd, Peter H.M.; Davies, Peter F.; Jayaraman, Girija; Jensen, Oliver E.; Lee, Jack; Parker, Kim H.; Popel, Aleksander S.; Secomb, Timothy W.; Siebes, Maria; Sherwin, Spencer J.; Shipley, Rebecca J.; Smith, Nicolas P.; van de Vosse, Frans N.
2013-01-01
A key aim of the cardiac Physiome Project is to develop theoretical models to simulate the functional behaviour of the heart under physiological and pathophysiological conditions. Heart function is critically dependent on the delivery of an adequate blood supply to the myocardium via the coronary vasculature. Key to this critical function of the coronary vasculature is system dynamics that emerge via the interactions of the numerous constituent components at a range of spatial and temporal scales. Here, we focus on several components for which theoretical approaches can be applied, including vascular structure and mechanics, blood flow and mass transport, flow regulation, angiogenesis and vascular remodelling, and vascular cellular mechanics. For each component, we summarise the current state of the art in model development, and discuss areas requiring further research. We highlight the major challenges associated with integrating the component models to develop a computational tool that can ultimately be used to simulate the responses of the coronary vascular system to changing demands and to diseases and therapies. PMID:21040741
Self-Assembled Magnetic Surface Swimmers: Theoretical Model
Aranson, Igor; Belkin, Maxim; Snezhko, Alexey
2009-03-01
The mechanisms of self-propulsion of living microorganisms are a fascinating phenomenon attracting enormous attention in the physics community. A new type of self-assembled micro-swimmers, magnetic snakes, is an excellent tool to model locomotion in a simple table-top experiment. The snakes self-assemble from a dispersion of magnetic microparticles suspended on the liquid-air interface and subjected to an alternating magnetic field. Formation and dynamics of these swimmers are captured in the framework of theoretical model coupling paradigm equation for the amplitude of surface waves, conservation law for the density of particles, and the Navier-Stokes equation for hydrodynamic flows. The results of continuum modeling are supported by hybrid molecular dynamics simulations of magnetic particles floating on the surface of fluid.
Naturalness of unknown physics: Theoretical models and experimental signatures
Kilic, Can
In the last few decades collider experiments have not only spectacularly confirmed the predictions of the Standard Model but also have not revealed any direct evidence for new physics beyond the SM, which has led theorists to devise numerous models where the new physics couples weakly to the SM or is simply beyond the reach of past experiments. While phenomenologically viable, many such models appear finely tuned, even contrived. This work illustrates three attempts at coming up with explanations to fine-tunings we observe in the world around us, such as the gauge hierarchy problem or the cosmological constant problem, emphasizing both the theoretical aspects of model building as well as possible experimental signatures. First we investigate the "Little Higgs" mechanism and work on a specifical model, the "Minimal Moose" to highlight its impact on precision observables in the SM, and illustrate that it does not require implausible fine-tuning. Next we build a supersymmetric model, the "Fat Higgs", with an extended gauge structure which becomes confining. This model, aside from naturally preserving the unification of the SM gauge couplings at high energies, also makes it possible to evade the bounds on the lightest Higgs boson mass which are quite restrictive in minimal SUSY scenarios. Lastly we take a look at a possible resolution of the cosmological constant problem through the mechanism of "Ghost Condensation" and dwell on astrophysical observables from the Lorentz Violating sector in this model. We use current experimental data to constrain the coupling of this sector to the SM.
Accuracy Analysis of a Box-wing Theoretical SRP Model
Wang, Xiaoya; Hu, Xiaogong; Zhao, Qunhe; Guo, Rui
2016-07-01
For Beidou satellite navigation system (BDS) a high accuracy SRP model is necessary for high precise applications especially with Global BDS establishment in future. The BDS accuracy for broadcast ephemeris need be improved. So, a box-wing theoretical SRP model with fine structure and adding conical shadow factor of earth and moon were established. We verified this SRP model by the GPS Block IIF satellites. The calculation was done with the data of PRN 1, 24, 25, 27 satellites. The results show that the physical SRP model for POD and forecast for GPS IIF satellite has higher accuracy with respect to Bern empirical model. The 3D-RMS of orbit is about 20 centimeters. The POD accuracy for both models is similar but the prediction accuracy with the physical SRP model is more than doubled. We tested 1-day 3-day and 7-day orbit prediction. The longer is the prediction arc length, the more significant is the improvement. The orbit prediction accuracy with the physical SRP model for 1-day, 3-day and 7-day arc length are 0.4m, 2.0m, 10.0m respectively. But they are 0.9m, 5.5m and 30m with Bern empirical model respectively. We apply this means to the BDS and give out a SRP model for Beidou satellites. Then we test and verify the model with Beidou data of one month only for test. Initial results show the model is good but needs more data for verification and improvement. The orbit residual RMS is similar to that with our empirical force model which only estimate the force for along track, across track direction and y-bias. But the orbit overlap and SLR observation evaluation show some improvement. The remaining empirical force is reduced significantly for present Beidou constellation.
Graph theoretical model of a sensorimotor connectome in zebrafish.
Michael Stobb
Full Text Available Mapping the detailed connectivity patterns (connectomes of neural circuits is a central goal of neuroscience. The best quantitative approach to analyzing connectome data is still unclear but graph theory has been used with success. We present a graph theoretical model of the posterior lateral line sensorimotor pathway in zebrafish. The model includes 2,616 neurons and 167,114 synaptic connections. Model neurons represent known cell types in zebrafish larvae, and connections were set stochastically following rules based on biological literature. Thus, our model is a uniquely detailed computational representation of a vertebrate connectome. The connectome has low overall connection density, with 2.45% of all possible connections, a value within the physiological range. We used graph theoretical tools to compare the zebrafish connectome graph to small-world, random and structured random graphs of the same size. For each type of graph, 100 randomly generated instantiations were considered. Degree distribution (the number of connections per neuron varied more in the zebrafish graph than in same size graphs with less biological detail. There was high local clustering and a short average path length between nodes, implying a small-world structure similar to other neural connectomes and complex networks. The graph was found not to be scale-free, in agreement with some other neural connectomes. An experimental lesion was performed that targeted three model brain neurons, including the Mauthner neuron, known to control fast escape turns. The lesion decreased the number of short paths between sensory and motor neurons analogous to the behavioral effects of the same lesion in zebrafish. This model is expandable and can be used to organize and interpret a growing database of information on the zebrafish connectome.
Graph theoretical model of a sensorimotor connectome in zebrafish.
Stobb, Michael; Peterson, Joshua M; Mazzag, Borbala; Gahtan, Ethan
2012-01-01
Mapping the detailed connectivity patterns (connectomes) of neural circuits is a central goal of neuroscience. The best quantitative approach to analyzing connectome data is still unclear but graph theory has been used with success. We present a graph theoretical model of the posterior lateral line sensorimotor pathway in zebrafish. The model includes 2,616 neurons and 167,114 synaptic connections. Model neurons represent known cell types in zebrafish larvae, and connections were set stochastically following rules based on biological literature. Thus, our model is a uniquely detailed computational representation of a vertebrate connectome. The connectome has low overall connection density, with 2.45% of all possible connections, a value within the physiological range. We used graph theoretical tools to compare the zebrafish connectome graph to small-world, random and structured random graphs of the same size. For each type of graph, 100 randomly generated instantiations were considered. Degree distribution (the number of connections per neuron) varied more in the zebrafish graph than in same size graphs with less biological detail. There was high local clustering and a short average path length between nodes, implying a small-world structure similar to other neural connectomes and complex networks. The graph was found not to be scale-free, in agreement with some other neural connectomes. An experimental lesion was performed that targeted three model brain neurons, including the Mauthner neuron, known to control fast escape turns. The lesion decreased the number of short paths between sensory and motor neurons analogous to the behavioral effects of the same lesion in zebrafish. This model is expandable and can be used to organize and interpret a growing database of information on the zebrafish connectome.
Gonzalez, Sergio C; Soto-Centeno, J Angel; Reed, David L
2011-09-19
Predicting the geographic distribution of widespread species through modeling is problematic for several reasons including high rates of omission errors. One potential source of error for modeling widespread species is that subspecies and/or races of species are frequently pooled for analyses, which may mask biologically relevant spatial variation within the distribution of a single widespread species. We contrast a presence-only maximum entropy model for the widely distributed oldfield mouse (Peromyscus polionotus) that includes all available presence locations for this species, with two composite maximum entropy models. The composite models either subdivided the total species distribution into four geographic quadrants or by fifteen subspecies to capture spatially relevant variation in P. polionotus distributions. Despite high Area Under the ROC Curve (AUC) values for all models, the composite species distribution model of P. polionotus generated from individual subspecies models represented the known distribution of the species much better than did the models produced by partitioning data into geographic quadrants or modeling the whole species as a single unit. Because the AUC values failed to describe the differences in the predictability of the three modeling strategies, we suggest using omission curves in addition to AUC values to assess model performance. Dividing the data of a widespread species into biologically relevant partitions greatly increased the performance of our distribution model; therefore, this approach may prove to be quite practical and informative for a wide range of modeling applications.
Theoretical modeling of the absorption spectrum of aqueous riboflavin
Zanetti-Polzi, Laura; Aschi, Massimiliano; Daidone, Isabella; Amadei, Andrea
2017-02-01
In this study we report the modeling of the absorption spectrum of riboflavin in water using a hybrid quantum/classical mechanical approach, the MD-PMM methodology. By means of MD-PMM calculations, with which the effect of riboflavin internal motions and of solvent interactions on the spectroscopic properties can be explicitly taken into account, we obtain an absorption spectrum in very good agreement with the experimental spectrum. In particular, the calculated peak maxima show a consistent improvement with respect to previous computational approaches. Moreover, the calculations show that the interaction with the environment may cause a relevant recombination of the gas-phase electronic states.
Kreutzmann, Lea
2013-01-01
The purpose of this research is to develop an international expansion strategy for the start-up company Hotel Quickly into the Indian market. The research was conducted by a combination of qualitative research methods, such as semi-structured in depth interviews with relevant industry representatives. Desk research was gathered from empirical studies and academic literature, such as research journals, books and published industry reports. The research indicated significant market potential fo...
Theoretical models for Type I and Type II supernova
Woosley, S.E.; Weaver, T.A.
1985-01-01
Recent theoretical progress in understanding the origin and nature of Type I and Type II supernovae is discussed. New Type II presupernova models characterized by a variety of iron core masses at the time of collapse are presented and the sensitivity to the reaction rate /sup 12/C(..cap alpha..,..gamma..)/sup 16/O explained. Stars heavier than about 20 M/sub solar/ must explode by a ''delayed'' mechanism not directly related to the hydrodynamical core bounce and a subset is likely to leave black hole remnants. The isotopic nucleosynthesis expected from these massive stellar explosions is in striking agreement with the sun. Type I supernovae result when an accreting white dwarf undergoes a thermonuclear explosion. The critical role of the velocity of the deflagration front in determining the light curve, spectrum, and, especially, isotopic nucleosynthesis in these models is explored. 76 refs., 8 figs.
Theoretical model of intravascular paramagnetic tracers effect on tissue relaxation
Kjølby, Birgitte Fuglsang; Østergaard, Leif; Kiselev, Valerij G
2006-01-01
that the relaxivity of intravascular contrast agents depends significantly on the host tissue. This agrees with experimental data by Johnson et al. (Magn Reson Med 2000;44:909). In particular, the present results suggest a several-fold increase in the relaxivity of Gd-based contrast agents in brain tissue compared...... with bulk blood. The enhancement of relaxation in tissue is due to the contrast in magnetic susceptibility between blood vessels and parenchyma induced by the presence of paramagnetic tracer. Beyond the perfusion measurements, the results can be applied to quantitation of functional MRI and to vessel size......The concentration of MRI tracers cannot be measured directly by MRI and is commonly evaluated indirectly using their relaxation effect. This study develops a comprehensive theoretical model to describe the transverse relaxation in perfused tissue caused by intravascular tracers. The model takes...
Validation of theoretical models through measured pavement response
Ullidtz, Per
1999-01-01
performance. The analytical models are based on a number of simplifications with respect to reality and must be verified experimentally.Different pressure gauges were installed in a sand, assumed to be a semi-infinite halfspace. The surface of the sand was loaded by a Falling Weight Deflectometer (FWD......) at different lateral positions with respect to the gauges. An integration of the stresses measured at the plane of the gauges showed that the total load recorded by the gauges was close to the loade imposed by the FWD, cofirming the reliability of the gauges. The theoretical stress calculated using continuum...... then used to derive the elastic parameters of the pavement layeres, that would produce deflections matching the measured deflections. Stresses and strains were then calculated at the position of the gauges and compared to the measured values. It was found that all analytical models would predict the tensile...
A Lifecourse Model of Multimorbidity Resilience: Theoretical and Research Developments.
Wister, Andrew V; Coatta, Katherine L; Schuurman, Nadine; Lear, Scott A; Rosin, Miriam; MacKey, Dawn
2016-04-01
The purpose of this article is to advance a Lifecourse Model of Multimorbidity Resilience. It focuses on the ways in which individuals face adversities associated with multimorbidity and regain a sense of wellness through a complex, dynamic phenomenon termed resilience. A comprehensive review of 112 publications (between 1995 and 2015) was conducted using several comprehensive electronic data bases. Two independent researchers extracted and synthesized resilience literature with specific applications to chronic illness. The article outlines five stages of theoretical development of resilience, synthesizes these with the aging and chronic illness literature, builds a rationale for a lifecourse approach to resilience, and applies the model to multimorbidity. Cultivating and maintaining resilience is fundamental to functioning and quality of life for those with multimorbidity. We found that there are a number of gaps in both basic and applied research that need to be filled to advance knowledge and practice based on resilience approaches.
Recent advances in theoretical models of respiratory mechanics
Bo Huo; Rui-Rong Fu
2012-01-01
As an important branch of biomedical engineering,respiratory mechanics helps to understand the physiology of the respiratory system and provides fundamental data for developing such clinical technologies as ventilators.To solve different clinical problems,researchers have developed numerous models at various scales that describe biological and mechanical properties of the respiratory system.During the past decade,benefiting from the continuous accumulation of clinical data and the dramatic progress of biomedical technologies (e.g.biomedical imaging),the theoretical modeling of respiratory mechanics has made remarkable progress regarding the macroscopic properties of the respiratory process,complexities of the respiratory system,gas exchange within the lungs,and the coupling interaction between lung and heart.The present paper reviews the advances in the above fields and proposes potential future projects.
Theoretical modelling of non-symmetric circular piezoelectric bimorphs
Brissaud, Michel
2006-05-01
This paper deals with the theoretical modelling of non-symmetric and symmetric circular bimorphs. The model is restricted to the study of flexural vibration modes having radial symmetry (axisymmetry), as is often the case for piezoelectric devices such as MEMs. The calculation of the resonance frequencies and the displacement of the non-symmetric circular bimorph has been carried out and the influence of the elastic and geometric parameters of the cement layer has been introduced into the model. As is shown, the modelling of non-symmetric and symmetric circular bimorphs reduces to the determination of two global quantities: the global rigidity DG and the global Poisson ratio σG of the bimorph which is then equivalent to a homogenous element. Consequently, the results obtained with elastic and homogeneous circular plates can be applied to non-symmetric and symmetric bimorphs with the only condition of using the global DG and σG. The new modelling was applied to bimorph functioning either as an actuator or as a sensor and having a simply supported or clamped edge. The electromechanical coupling factor of flexure modes has been calculated and compared to the radial mode. Comparison between analytical models and simulations using the finite-element method is given and discussed.
Behavioral models as theoretical frames to analyze the business objective
Hernán Alonso Bafico
2015-12-01
Full Text Available This paper examines Pfeffer’s Models of Behavior and connects each of them with attributes of the definition of the firm’s objective, assumed as the maximization of the sustainable, long term valor of the residual claims.Each of the five models of behavior (rational, social, moral, retrospective and cognitive contributes to the decision making and goal setting processes with its particular and complementary elements. From those assuming complete rationality and frictionless markets, to the models emphasizing the role of ethical positions, and the presence of perceptive and cognitive mechanisms. The analysis highlights the main contributions of critical theories and models of behavior, underlining their focus on non-traditional variables, regarded as critical inputs for goal setting processes and designing alternative executive incentive schemes. The explicit consideration of those variables does not indicate the need for a new definition of corporate objective. The maximization of the long term value of the shareholders’ claims still defines the relevant objective function of the firm, remaining as the main yardstick of corporate performance.Behavioral models are recognized as important tools to help managers direct their attention to long term strategies. In the last part, we comment on the relationship between the objective function and behavioral models, from the practitioners’ perspective.Key words: Firm Objectives, Behavioral Models, Value Maximization, Stakeholder Theory.
Relevance Theory as model for analysing visual and multimodal communication
C. Forceville
2014-01-01
Elaborating on my earlier work (Forceville 1996: chapter 5, 2005, 2009; see also Yus 2008), I will here sketch how discussions of visual and multimodal discourse can be embedded in a more general theory of communication and cognition: Sperber and Wilson’s Relevance Theory/RT (Sperber and Wilson 1986
Raindrop size distribution: Fitting performance of common theoretical models
Adirosi, E.; Volpi, E.; Lombardo, F.; Baldini, L.
2016-10-01
Modelling raindrop size distribution (DSD) is a fundamental issue to connect remote sensing observations with reliable precipitation products for hydrological applications. To date, various standard probability distributions have been proposed to build DSD models. Relevant questions to ask indeed are how often and how good such models fit empirical data, given that the advances in both data availability and technology used to estimate DSDs have allowed many of the deficiencies of early analyses to be mitigated. Therefore, we present a comprehensive follow-up of a previous study on the comparison of statistical fitting of three common DSD models against 2D-Video Distrometer (2DVD) data, which are unique in that the size of individual drops is determined accurately. By maximum likelihood method, we fit models based on lognormal, gamma and Weibull distributions to more than 42.000 1-minute drop-by-drop data taken from the field campaigns of the NASA Ground Validation program of the Global Precipitation Measurement (GPM) mission. In order to check the adequacy between the models and the measured data, we investigate the goodness of fit of each distribution using the Kolmogorov-Smirnov test. Then, we apply a specific model selection technique to evaluate the relative quality of each model. Results show that the gamma distribution has the lowest KS rejection rate, while the Weibull distribution is the most frequently rejected. Ranking for each minute the statistical models that pass the KS test, it can be argued that the probability distributions whose tails are exponentially bounded, i.e. light-tailed distributions, seem to be adequate to model the natural variability of DSDs. However, in line with our previous study, we also found that frequency distributions of empirical DSDs could be heavy-tailed in a number of cases, which may result in severe uncertainty in estimating statistical moments and bulk variables.
Coordination-theoretic approach to modelling grid service composition process
Meng Qian; Zhong Liu; Jing Wang; Li Yao; Weiming Zhang
2010-01-01
A grid service composite process is made up of complex coordinative activities.Developing the appropriate model of grid service coordinative activities is an important foundation for the grid service composition.According to the coordination theory,this paper elaborates the process of the grid service composition by using UML 2.0,and proposes an approach to modelling the grid service composition process based on the coordination theory.This approach helps not only to analyze accurately the task activities and relevant dependencies among task activities,but also to facilitate the adaptability of the grid service orchestration to further realize the connectivity,timeliness,appropriateness and expansibility of the grid service composition.
A theoretical model for assessing the sustainability Of ecosystem services
Feng Ling; Cheng Shengkui; Su Hua; Min Qingwen
2008-01-01
The Value of the World's Ecosystem Services and Natural Capital by Costanza in 1997 is generally regarded as a monument for the research of valuing ecosystem services. However, the classification of ecosystem services, the method of various services summation and the purpose for static global value had be confronted by many criticisms. Based on the summary of these criticisms, suggestions, related function assessment and further study direction, the sustainability of ecosystem services is presented The two basic indicators in ecology, productivity and biodiversity, respectively charactering the ability of producing and self-organizing, not only represent the internal function of ecosystem, but also are proportioned to its external function of supporting and providing for human life On presenting the general form of ecosystem services assessment, this paper improves the mathematical formula giving a function adjusting coefficient composed of productivity and biodiversity. Theoretically, the integration of the two indicators reflects the changes of ecosystem services at spatial and temporal scales, can physically assess the sustability of ecosystem services, and build a firm scientific fundament of value assessment for ecosystem services Objectively, its application should be strictly tested in next step.Ecosystem services; theoretical model; Sustainability; Bio-productivity; Biodiversity
Theoretical model of blood flow measurement by diffuse correlation spectroscopy
Sakadžić, Sava; Boas, David A.; Carp, Stefan
2017-02-01
Diffuse correlation spectroscopy (DCS) is a noninvasive method to quantify tissue perfusion from measurements of the intensity temporal autocorrelation function of diffusely scattered light. However, DCS autocorrelation function measurements in tissue better match theoretical predictions based on the diffusive motion of the scatterers than those based on a model where the advective nature of blood flow dominates the stochastic properties of the scattered light. We have recently shown using Monte Carlo (MC) simulations and assuming a simplistic vascular geometry and laminar flow profile that the diffusive nature of the DCS autocorrelation function decay is likely a result of the shear-induced diffusion of the red blood cells. Here, we provide theoretical derivations supporting and generalizing the previous MC results. Based on the theory of diffusing-wave spectroscopy, we derive an expression for the autocorrelation function along the photon path through a vessel that takes into account both diffusive and advective scatterer motion, and we provide the solution for the DCS autocorrelation function in a semi-infinite geometry. We also derive the correlation diffusion and correlation transfer equation, which can be applied for an arbitrary sample geometry. Further, we propose a method to take into account realistic vascular morphology and flow profile.
Spatial Segregation, Redistribution and Welfare: A Theoretical Model
Tommaso Gabrieli
2016-03-01
Full Text Available This paper develops a theoretical model focusing on the effect that different neighborhood compositions can have on the formation of individual beliefs about economic opportunities. Specifically we highlight two effects that spatial segregation may have: (1 it can efficiently separate the individual effort choices of highly and low productive individuals, (2 it may imply that the median voter imposes a level of redistribution that is inefficient from the aggregate point of view. The trade-off implies that segregated and non-segregated cities may present very similar levels of aggregate welfare. We employ this framework to discuss how the structure of cities can play a role in the determination of US-type and Europe-type politico-economic equilibria and the implications for planning policies.
Exploring a type-theoretic approach to accessibility constraint modelling
Pogodalla, Sylvain
2008-01-01
The type-theoretic modelling of DRT that [degroote06] proposed features continuations for the management of the context in which a clause has to be interpreted. This approach, while keeping the standard definitions of quantifier scope, translates the rules of the accessibility constraints of discourse referents inside the semantic recipes. In this paper, we deal with additional rules for these accessibility constraints. In particular in the case of discourse referents introduced by proper nouns, that negation does not block, and in the case of rhetorical relations that structure discourses. We show how this continuation-based approach applies to those accessibility constraints and how we can consider the parallel management of various principles.
Examining Asymmetrical Relationships of Organizational Learning Antecedents: A Theoretical Model
Ery Tri Djatmika
2016-02-01
Full Text Available Global era is characterized by highly competitive advantage market demand. Responding to the challenge of rapid environmental changes, organizational learning is becoming a strategic way and solution to empower people themselves within the organization in order to create a novelty as valuable positioning source. For research purposes, determining the influential antecedents that affect organizational learning is vital to understand research-based solutions given for practical implications. Accordingly, identification of variables examined by asymmetrical relationships is critical to establish. Possible antecedent variables come from organizational and personal point of views. It is also possible to include a moderating one. A proposed theoretical model of asymmetrical effects of organizational learning and its antecedents is discussed in this article.
Theoretical temperature model with experimental validation for CLIC Accelerating Structures
AUTHOR|(CDS)2126138; Vamvakas, Alex; Alme, Johan
Micron level stability of the Compact Linear Collider (CLIC) components is one of the main requirements to meet the luminosity goal for the future $48 \\,km$ long underground linear accelerator. The radio frequency (RF) power used for beam acceleration causes heat generation within the aligned structures, resulting in mechanical movements and structural deformations. A dedicated control of the air- and water- cooling system in the tunnel is therefore crucial to improve alignment accuracy. This thesis investigates the thermo-mechanical behavior of the CLIC Accelerating Structure (AS). In CLIC, the AS must be aligned to a precision of $10\\,\\mu m$. The thesis shows that a relatively simple theoretical model can be used within reasonable accuracy to predict the temperature response of an AS as a function of the applied RF power. During failure scenarios or maintenance interventions, the RF power is turned off resulting in no heat dissipation and decrease in the overall temperature of the components. The theoretica...
A theoretical model of phase transitions in the human brain.
Jirsa, V K; Friedrich, R; Haken, H; Kelso, J A
1994-01-01
An experiment using a multisensor SQUID (superconducting quantum interference device) array was performed by Kelso and colleagues (1992) which combined information from three different sources: perception, motor response, and brain signals. When an acoustic stimulus frequency is changed systematically, a spontaneous transition in coordination occurs at a critical frequency in both motor behavior and brain signals. Qualitatively analogous transitions are known for physical and biological systems such as changes in the coordination of human hand movements (Kelso 1981, 1984). In this paper we develop a theoretical model based on methods from the interdisciplinary field of synergetics (Haken 1983, 1987) and nonlinear oscillator theory that reproduces the main experimental features very well and suggests a formulation of a fundamental biophysical coupling.
A model theoretic Baire category theorem for simple theories
Shami, Ziv
2009-01-01
We define the class of $\\tilde\\tau_{low}^f$-sets. This is a class of type-definable sets defined in terms of forking by low formulas. We prove a model theoretic Baire category theorem for $\\tilde\\tau_{low}^f$-sets in a countable simple theory in which the extension property is first-order and show some of its applications. A typical application is the following. Let $T$ be a countable theory with the wnfcp (weak nonfinite cover property) and assume for every non-algebraic $a$ there exists a non-algebraic $a'\\acl(a)$ such that $SU(a')<\\omega$. Then there exists a weakly-minimal formula with parameters.
Penetration of alkali atoms throughout a graphene membrane: theoretical modeling.
Boukhvalov, D W; Virojanadara, C
2012-03-07
Theoretical studies of penetration of various alkali atoms (Li, Na, Rb, Cs) throughout a graphene membrane grown on a silicon carbide substrate are reported and compared with recent experimental results. Results of first principles modeling demonstrate a rather low (about 0.8 eV) energy barrier for the formation of temporary defects in the carbon layer required for the penetration of Li at a high concentration of adatoms, a higher (about 2 eV) barrier for Na, and barriers above 4 eV for Rb and Cs. Experiments prove migration of lithium adatoms from the graphene surface to the buffer layer and SiC substrate at room temperature, sodium at 100 °C and impenetrability of the graphene membrane for Rb and Cs. Differences between epitaxial and free-standing graphene for the penetration of alkali ions are also discussed.
Houck, Hannes A.; De Bruycker, Kevin; Billiet, Stijn; Dhanis, Bastiaan; Goossens, Hannelore; Catak, Saron; Van Speybroeck, Veronique
2017-01-01
The reaction of triazolinediones (TADs) and indoles is of particular interest for polymer chemistry applications, as it is a very fast and irreversible additive-free process at room temperature, but can be turned into a dynamic covalent bond forming process at elevated temperatures, giving a reliable bond exchange or ‘transclick’ reaction. In this paper, we report an in-depth study aimed at controlling the TAD–indole reversible click reactions through rational design of modified indole reaction partners. This has resulted in the identification of a novel class of easily accessible indole derivatives that give dynamic TAD-adduct formation at significantly lower temperatures. We further demonstrate that these new substrates can be used to design a directed cascade of click reactions of a functionalized TAD moiety from an initial indole reaction partner to a second indole, and finally to an irreversible reaction partner. This controlled sequence of click and transclick reactions of a single TAD reagent between three different substrates has been demonstrated both on small molecule and macromolecular level, and the factors that control the reversibility profiles have been rationalized and guided by mechanistic considerations supported by theoretical calculations. PMID:28507685
Theoretical model for forming limit diagram predictions without initial inhomogeneity
Gologanu, Mihai; Comsa, Dan Sorin; Banabic, Dorel
2013-05-01
We report on our attempts to build a theoretical model for determining forming limit diagrams (FLD) based on limit analysis that, contrary to the well-known Marciniak and Kuczynski (M-K) model, does not assume the initial existence of a region with material or geometrical inhomogeneity. We first give a new interpretation based on limit analysis for the onset of necking in the M-K model. Considering the initial thickness defect along a narrow band as postulated by the M-K model, we show that incipient necking is a transition in the plastic mechanism from one of plastic flow in both the sheet and the band to another one where the sheet becomes rigid and all plastic deformation is localized in the band. We then draw on some analogies between the onset of necking in a sheet and the onset of coalescence in a porous bulk body. In fact, the main advance in coalescence modeling has been based on a similar limit analysis with an important new ingredient: the evolution of the spatial distribution of voids, due to the plastic deformation, creating weaker regions with higher porosity surrounded by sound regions with no voids. The onset of coalescence is precisely the transition from a mechanism of plastic deformation in both regions to another one, where the sound regions are rigid. We apply this new ingredient to a necking model based on limit analysis, for the first quadrant of the FLD and a porous sheet. We use Gurson's model with some recent extensions to model the porous material. We follow both the evolution of a homogeneous sheet and the evolution of the distribution of voids. At each moment we test for a potential change of plastic mechanism, by comparing the stresses in the uniform region to those in a virtual band with a larger porosity. The main difference with the coalescence of voids in a bulk solid is that the plastic mechanism for a sheet admits a supplementary degree of freedom, namely the change in the thickness of the virtual band. For strain ratios close to
Measuring and Managing Value Co-Creation Process: Overview of Existing Theoretical Models
Monika Skaržauskaitė
2013-08-01
Full Text Available Purpose — the article is to provide a holistic view on concept of value co-creation and existing models for measuring and managing it by conducting theoretical analysis of scientific literature sources targeting the integration of various approaches. Most important and relevant results of the literature study are presented with a focus on changed roles of organizations and consumers. This article aims at contributing theoretically to the research stream of measuring co-creation of value in order to gain knowledge for improvement of organizational performance and enabling new and innovative means of value creation. Design/methodology/approach. The nature of this research is exploratory – theoretical analysis and synthesis of scientific literature sources targeting the integration of various approaches was performed. This approach was chosen due to the absence of established theory on models of co-creation, possible uses in organizations and systematic overview of tools measuring/suggesting how to measure co-creation. Findings. While the principles of managing and measuring co-creation in regards of consumer motivation and involvement are widely researched, little attempt has been made to identify critical factors and create models dealing with organizational capabilities and managerial implications of value co-creation. Systematic analysis of literature revealed a gap not only in empirical research concerning organization’s role in co-creation process, but in theoretical and conceptual levels, too. Research limitations/implications. The limitations of this work as a literature review lies in its nature – the complete reliance on previously published research papers and the availability of these studies. For a deeper understanding of co-creation management and for developing models that can be used in real-life organizations, a broader theoretical, as well as empirical, research is necessary. Practical implications. Analysis of the
Modelling Crowd Dynamics: a Multiscale, Measure-theoretical Approach
Evers, Joep
2011-01-01
We present a strategy capable of describing basic features of the dynamics of crowds. The behaviour of the crowd is considered from a twofold perspective. We examine both the large scale behaviour of the crowd, and phenomena happening at the individual pedestrian's level. We unify micro and macro in a single model, by working with general mass measures and their transport. We improve existing modelling by coupling a measure-theoretical framework with basic ideas of mixture theory formulated in terms of measures. This strategy allows us to define several constituents of the crowd, each having its own partial velocity. We can thus examine the interaction between subpopulations that have distinct characteristics. We give special features to those pedestrians that are represented by the microscopic (discrete) part. In real life they would play the role of leaders, predators etc. Since we are interested in the global behaviour of the rest of the crowd, we model this part as a continuum. By identifying a suitable c...
A theoretical intellectual capital model applied to cities
José Luis Alfaro Navarro
2013-06-01
Full Text Available New Management Information Systems (MIS are necessary at local level as the main source of wealth creation. Therefore, tools and approaches that provide a full future vision of any organization should be a strategic priority for economic development. In this line, cities are “centers of knowledge and sources of growth and innovation” and integrated urban development policies are necessary. These policies support communication networks and optimize location structures as strategies that provide opportunities for social and democratic participation for the citizens. This paper proposes a theoretical model to measure and evaluate the cities intellectual capital that allows determine what we must take into account to make cities a source of wealth, prosperity, welfare and future growth. Furthermore, local intellectual capital provides a long run vision. Thus, in this paper we develop and explain how to implement a model to estimate intellectual capital in cities. In this sense, our proposal is to provide a model for measuring and managing intellectual capital using socio-economic indicators for cities. These indicators offer a long term picture supported by a comprehensive strategy for those who occupy the local space, infrastructure for implementation and management of the environment for its development.
A Production Model for Construction: A Theoretical Framework
Ricardo Antunes
2015-03-01
Full Text Available The building construction industry faces challenges, such as increasing project complexity and scope requirements, but shorter deadlines. Additionally, economic uncertainty and rising business competition with a subsequent decrease in profit margins for the industry demands the development of new approaches to construction management. However, the building construction sector relies on practices based on intuition and experience, overlooking the dynamics of its production system. Furthermore, researchers maintain that the construction industry has no history of the application of mathematical approaches to model and manage production. Much work has been carried out on how manufacturing practices apply to construction projects, mostly lean principles. Nevertheless, there has been little research to understand the fundamental mechanisms of production in construction. This study develops an in-depth literature review to examine the existing knowledge about production models and their characteristics in order to establish a foundation for dynamic production systems management in construction. As a result, a theoretical framework is proposed, which will be instrumental in the future development of mathematical production models aimed at predicting the performance and behaviour of dynamic project-based systems in construction.
Extracting the relevant delays in time series modelling
Goutte, Cyril
1997-01-01
selection, and more precisely stepwise forward selection. The method is compared to other forward selection schemes, as well as to a nonparametric tests aimed at estimating the embedding dimension of time series. The final application extends these results to the efficient estimation of FIR filters on some......In this contribution, we suggest a convenient way to use generalisation error to extract the relevant delays from a time-varying process, i.e. the delays that lead to the best prediction performance. We design a generalisation-based algorithm that takes its inspiration from traditional variable...
Mandal, Monalisa; Mukhopadhyay, Anirban
2014-01-01
The purpose of feature selection is to identify the relevant and non-redundant features from a dataset. In this article, the feature selection problem is organized as a graph-theoretic problem where a feature-dissimilarity graph is shaped from the data matrix. The nodes represent features and the edges represent their dissimilarity. Both nodes and edges are given weight according to the feature's relevance and dissimilarity among the features, respectively. The problem of finding relevant and non-redundant features is then mapped into densest subgraph finding problem. We have proposed a multiobjective particle swarm optimization (PSO)-based algorithm that optimizes average node-weight and average edge-weight of the candidate subgraph simultaneously. The proposed algorithm is applied for identifying relevant and non-redundant disease-related genes from microarray gene expression data. The performance of the proposed method is compared with that of several other existing feature selection techniques on different real-life microarray gene expression datasets.
Monalisa Mandal
Full Text Available The purpose of feature selection is to identify the relevant and non-redundant features from a dataset. In this article, the feature selection problem is organized as a graph-theoretic problem where a feature-dissimilarity graph is shaped from the data matrix. The nodes represent features and the edges represent their dissimilarity. Both nodes and edges are given weight according to the feature's relevance and dissimilarity among the features, respectively. The problem of finding relevant and non-redundant features is then mapped into densest subgraph finding problem. We have proposed a multiobjective particle swarm optimization (PSO-based algorithm that optimizes average node-weight and average edge-weight of the candidate subgraph simultaneously. The proposed algorithm is applied for identifying relevant and non-redundant disease-related genes from microarray gene expression data. The performance of the proposed method is compared with that of several other existing feature selection techniques on different real-life microarray gene expression datasets.
A theoretical model of co-worker responses to work reintegration processes.
Dunstan, Debra A; Maceachen, Ellen
2014-06-01
Emerging research has shown that co-workers have a significant influence on the return-to-work outcomes of partially fit ill or injured employees. By drawing on theoretical findings from the human resource and wider behavioral sciences literatures, our goal was to formulate a theoretical model of the influences on and outcomes of co-worker responses within work reintegration. From a search of 15 data bases covering the social sciences, business and medicine, we identified articles containing models of the factors that influence co-workers' responses to disability accommodations; and, the nature and impact of co-workers' behaviors on employee outcomes. To meet our goal, we combined identified models to form a comprehensive model of the relevant factors and relationships. Internal consistency and externally validity were assessed. The combined model illustrates four key findings: (1) co-workers' behaviors towards an accommodated employee are influenced by attributes of that employee, the illness or injury, the co-worker themselves, and the work environment; (2) the influences-behaviour relationship is mediated by perceptions of the fairness of the accommodation; (3) co-workers' behaviors affect all work reintegration outcomes; and (4) co-workers' behaviours can vary from support to antagonism and are moderated by type of support required, the social intensity of the job, and the level of antagonism. Theoretical models from the wider literature are useful for understanding the impact of co-workers on the work reintegration process. To achieve optimal outcomes, co-workers need to perceive the arrangements as fair. Perceptions of fairness might be supported by co-workers' collaborative engagement in the planning, monitoring and review of work reintegration activities.
Experimental Investigation and Theoretical Modeling of Nanosilica Activity in Concrete
Han-Seung Lee
2014-01-01
Full Text Available This paper presents experimental investigations and theoretical modeling of the hydration reaction of nanosilica blended concrete with different water-to-binder ratios and different nanosilica replacement ratios. The developments of chemically bound water contents, calcium hydroxide contents, and compressive strength of Portland cement control specimens and nanosilica blended specimens were measured at different ages: 1 day, 3 days, 7 days, 14 days, and 28 days. Due to the pozzolanic reaction of nanosilica, the contents of calcium hydroxide in nanosilica blended pastes are considerably lower than those in the control specimens. Compared with the control specimens, the extent of compressive strength enhancement in the nanosilica blended specimens is much higher at early ages. Additionally, a blended cement hydration model that considers both the hydration reaction of cement and the pozzolanic reaction of nanosilica is proposed. The properties of nanosilica blended concrete during hardening were evaluated using the degree of hydration of cement and the reaction degree of nanosilica. The calculated chemically bound water contents, calcium hydroxide contents, and compressive strength were generally consistent with the experimental results.
Islamic Theoretical Intertemporal Model of the Current Account
Hassan Belkacem Ghassan
2016-06-01
Full Text Available This paper aims to develop an Islamic intertemporal model of the current account based on the prevailing theoretical and empirical literature of PVMCA (Obstfeld and Rogoff, 1996, Cerrato et al., 2014. The proposed model is based on the budget constraint of the present and future consumption, which depends on the obligatory Zakat from the income and assets, the return rate on the owned assets, the inheritance linking previous to subsequent generation. Using logarithmic utility function, featured by a unitary elasticity of intertemporal substitution and a unitary coefficient of relative risk aversion, we show through Euler equation of consumption that there is an inverse relationship between consumption growth from the last age to the first one and the Zakat rate on assets. The outcomes of this result are that the Zakat on assets disciplines the consumer to have more rationality in consumption, and allows additional marginal assets for future generations. By assuming a unitary subjective discount rate, we indicate that the more the return rate on assets is high, the more the consumption growth between today and tomorrow will be fast. Through the budget constraint, if Zakat rate on the Zakatable assets is greater than Zakat rate on income, this leads to a relative expansion in private consumption of the wealthy group. Besides, we point out that an increase in return rate on assets, can drive to increasing or decreasing current consumption, because the substitution and income effects work in opposite ways.
Strengthening Theoretical Testing in Criminology Using Agent-based Modeling.
Johnson, Shane D; Groff, Elizabeth R
2014-07-01
The Journal of Research in Crime and Delinquency (JRCD) has published important contributions to both criminological theory and associated empirical tests. In this article, we consider some of the challenges associated with traditional approaches to social science research, and discuss a complementary approach that is gaining popularity-agent-based computational modeling-that may offer new opportunities to strengthen theories of crime and develop insights into phenomena of interest. Two literature reviews are completed. The aim of the first is to identify those articles published in JRCD that have been the most influential and to classify the theoretical perspectives taken. The second is intended to identify those studies that have used an agent-based model (ABM) to examine criminological theories and to identify which theories have been explored. Ecological theories of crime pattern formation have received the most attention from researchers using ABMs, but many other criminological theories are amenable to testing using such methods. Traditional methods of theory development and testing suffer from a number of potential issues that a more systematic use of ABMs-not without its own issues-may help to overcome. ABMs should become another method in the criminologists toolbox to aid theory testing and falsification.
A theoretical model for the Lorentz force particle analyzer
Moreau, René; Tao, Zhen; Wang, Xiaodong
2016-07-01
In a previous paper [X. Wang et al., J. Appl. Phys. 120, 014903 (2016)], several experimental devices have been presented, which demonstrate the efficiency of electromagnetic techniques for detecting and sizing electrically insulating particles entrained in the flow of a molten metal. In each case, a non-uniform magnetic field is applied across the flow of the electrically conducting liquid, thereby generating a braking Lorentz force on this moving medium and a reaction force on the magnet, which tends to be entrained in the flow direction. The purpose of this letter is to derive scaling laws for this Lorentz force from an elementary theoretical model. For simplicity, as in the experiments, the flowing liquid is modeled as a solid body moving with a uniform velocity U. The eddy currents in the moving domain are derived from the classic induction equation and Ohm's law, and expressions for the Lorentz force density j ×B and for its integral over the entire moving domain follow. The insulating particles that are eventually present and entrained with this body are then treated as small disturbances in a classic perturbation analysis, thereby leading to scaling laws for the pulses they generate in the Lorentz force. The purpose of this letter is both to illustrate the eddy currents without and with insulating particles in the electrically conducting liquid and to derive a key relation between the pulses in the Lorentz force and the main parameters (particle volume and dimensions of the region subjected to the magnetic field).
Studies of Chinese speakers with dysarthria: informing theoretical models.
Whitehill, Tara L
2010-01-01
Most theoretical models of dysarthria have been developed based on research using individuals speaking English or other Indo-European languages. Studies of individuals with dysarthria speaking other languages can allow investigation into the universality of such models, and the interplay between language-specific and language-universal aspects of dysarthria. In this article, studies of Cantonese- and Mandarin-Chinese speakers with dysarthria are reviewed. The studies focused on 2 groups of speakers: those with cerebral palsy and those with Parkinson's disease. Key findings are compared with similar studies of English speakers. Since Chinese is tonal in nature, the impact of dysarthria on lexical tone has received considerable attention in the literature. The relationship between tone [which involves fundamental frequency (F(0)) control at the syllable level] and intonation (involving F(0) control at the sentential level) has received more recent attention. Many findings for Chinese speakers with dysarthria support earlier findings for English speakers, thus affirming the language-universal aspect of dysarthria. However, certain differences, which can be attributed to the distinct phonologies of Cantonese and Mandarin, highlight the language-specific aspects of the condition.
Theoretical Model and Dynamic Analysis of Soft Yoke Mooring System
无
2008-01-01
As a popular solution for mooring an FPSO (Floating Production, Storage and Offloading) permanently in shallow water, the soft yoke mooring system has been widely used in ocean oil production activities in the Bohai Bay of China. In order to simulate the interaction mechanism and conduct dynamic analysis of the soft yoke mooring system, a theoretical model with basic dynamic equations is established. A numerical iteration algorithm based on error estimation is developed to solve the equations and calculate the dynamic response of the mooring system due to FPSO motions. Validation is conducted by wave basin experimentation. It is shown that the numerical simulation takes only a few iteration times and the final errors are small. Furthermore, the calculated results of both the static and dynamic responses agree well with those ones obtained by the model test. It indicates that the efficiency, the precision, the reliability and the validity of the developed numerical algorithm and program are rather good. It is proposed to develop a real-time monitoring system to further monitor the dynamic performance of the FPSO with a soft yoke mooring system under various real sea environments.
A theoretical model for analysing gender bias in medicine
Johansson Eva E
2009-08-01
Full Text Available Abstract During the last decades research has reported unmotivated differences in the treatment of women and men in various areas of clinical and academic medicine. There is an ongoing discussion on how to avoid such gender bias. We developed a three-step-theoretical model to understand how gender bias in medicine can occur and be understood. In this paper we present the model and discuss its usefulness in the efforts to avoid gender bias. In the model gender bias is analysed in relation to assumptions concerning difference/sameness and equity/inequity between women and men. Our model illustrates that gender bias in medicine can arise from assuming sameness and/or equity between women and men when there are genuine differences to consider in biology and disease, as well as in life conditions and experiences. However, gender bias can also arise from assuming differences when there are none, when and if dichotomous stereotypes about women and men are understood as valid. This conceptual thinking can be useful for discussing and avoiding gender bias in clinical work, medical education, career opportunities and documents such as research programs and health care policies. Too meet the various forms of gender bias, different facts and measures are needed. Knowledge about biological differences between women and men will not reduce bias caused by gendered stereotypes or by unawareness of health problems and discrimination associated with gender inequity. Such bias reflects unawareness of gendered attitudes and will not change by facts only. We suggest consciousness-rising activities and continuous reflections on gender attitudes among students, teachers, researchers and decision-makers.
Theoretical Modelling Methods for Thermal Management of Batteries
Bahman Shabani
2015-09-01
Full Text Available The main challenge associated with renewable energy generation is the intermittency of the renewable source of power. Because of this, back-up generation sources fuelled by fossil fuels are required. In stationary applications whether it is a back-up diesel generator or connection to the grid, these systems are yet to be truly emissions-free. One solution to the problem is the utilisation of electrochemical energy storage systems (ESS to store the excess renewable energy and then reusing this energy when the renewable energy source is insufficient to meet the demand. The performance of an ESS amongst other things is affected by the design, materials used and the operating temperature of the system. The operating temperature is critical since operating an ESS at low ambient temperatures affects its capacity and charge acceptance while operating the ESS at high ambient temperatures affects its lifetime and suggests safety risks. Safety risks are magnified in renewable energy storage applications given the scale of the ESS required to meet the energy demand. This necessity has propelled significant effort to model the thermal behaviour of ESS. Understanding and modelling the thermal behaviour of these systems is a crucial consideration before designing an efficient thermal management system that would operate safely and extend the lifetime of the ESS. This is vital in order to eliminate intermittency and add value to renewable sources of power. This paper concentrates on reviewing theoretical approaches used to simulate the operating temperatures of ESS and the subsequent endeavours of modelling thermal management systems for these systems. The intent of this review is to present some of the different methods of modelling the thermal behaviour of ESS highlighting the advantages and disadvantages of each approach.
Berezovska, Ganna; Mostarda, Stefano; Rao, Francesco
2012-01-01
Molecular simulations as well as single molecule experiments have been widely analyzed in terms order parameters, the latter representing candidate probes for the relevant degrees of freedom. Notwithstanding this approach is very intuitive, mounting evidence showed that such description is not accurate, leading to ambiguous definitions of states and wrong kinetics. To overcome these limitations a framework making use of order parameter fluctuations in conjunction with complex network analysis is investigated. Derived from recent advances in the analysis of single molecule time traces, this approach takes into account of the fluctuations around each time point to distinguish between states that have similar values of the order parameter but different dynamics. Snapshots with similar fluctuations are used as nodes of a transition network, the clusterization of which into states provides accurate Markov-State-Models of the system under study. Application of the methodology to theoretical models with a noisy orde...
Relevance of animal models to human tardive dyskinesia
Blanchet Pierre J
2012-03-01
Full Text Available Abstract Tardive dyskinesia remains an elusive and significant clinical entity that can possibly be understood via experimentation with animal models. We conducted a literature review on tardive dyskinesia modeling. Subchronic antipsychotic drug exposure is a standard approach to model tardive dyskinesia in rodents. Vacuous chewing movements constitute the most common pattern of expression of purposeless oral movements and represent an impermanent response, with individual and strain susceptibility differences. Transgenic mice are also used to address the contribution of adaptive and maladaptive signals induced during antipsychotic drug exposure. An emphasis on non-human primate modeling is proposed, and past experimental observations reviewed in various monkey species. Rodent and primate models are complementary, but the non-human primate model appears more convincingly similar to the human condition and better suited to address therapeutic issues against tardive dyskinesia.
A review of models relevant to road safety.
Hughes, B P; Newstead, S; Anund, A; Shu, C C; Falkmer, T
2015-01-01
It is estimated that more than 1.2 million people die worldwide as a result of road traffic crashes and some 50 million are injured per annum. At present some Western countries' road safety strategies and countermeasures claim to have developed into 'Safe Systems' models to address the effects of road related crashes. Well-constructed models encourage effective strategies to improve road safety. This review aimed to identify and summarise concise descriptions, or 'models' of safety. The review covers information from a wide variety of fields and contexts including transport, occupational safety, food industry, education, construction and health. The information from 2620 candidate references were selected and summarised in 121 examples of different types of model and contents. The language of safety models and systems was found to be inconsistent. Each model provided additional information regarding style, purpose, complexity and diversity. In total, seven types of models were identified. The categorisation of models was done on a high level with a variation of details in each group and without a complete, simple and rational description. The models identified in this review are likely to be adaptable to road safety and some of them have previously been used. None of systems theory, safety management systems, the risk management approach, or safety culture was commonly or thoroughly applied to road safety. It is concluded that these approaches have the potential to reduce road trauma.
Tourassi, Georgia D.; Floyd, Carey E., Jr.
2004-05-01
The purpose of the study was to develop and evaluate a content-based image retrieval (CBIR) approach for computer-assisted diagnosis of masses detected in screening mammograms. The system follows an information theoretic retrieval scheme with a BIRADS-based relevance feedback (RF) algorithm. Initially, a knowledge databank of 365 mammographic regions of interest (ROIs) was created. They were all 512x512 pixel ROIs extracted from DDSM mammograms digitized using the Lumisys digitizer. The ROIs were extracted around the known locations of the annotated masses. Specifically, there were 177 ROIs depicting a biopsy-proven malignant mass and 188 ROIs with a benign mass. Subsequently, the CBIR algorithm was implemented using mutual information (MI) as the similarity metric for image retrieval. The CBIR algorithm formed the basis of a knowledge-based CAD system. Given a databank of mammographic masses with known pathology, a query mass was evaluated. Based on their information content, all similar masses in the databank were retrieved. A relevance feedback algorithm based on BIRADS findings was implemented to determine the relevance factor of the retrieved masses. Finally, a decision index was calculated using the query's k best matches. The decision index effectively combined the similarity metric of the retrieved cases and their relevance factor into a prediction regarding the malignancy status of the mass depicted in the query ROI. ROC analysis was to evaluate diagnostic performance. Performance improved dramatically with the incorporation of the relevance feedback algorithm. Overall, the CAD system achieved ROC area index AZ= 0.86+/-0.02 for the diagnosis of masses in screening mammograms.
Relevance of a Managerial Decision-Model to Educational Administration.
Lundin, Edward.; Welty, Gordon
The rational model of classical economic theory assumes that the decision maker has complete information on alternatives and consequences, and that he chooses the alternative that maximizes expected utility. This model does not allow for constraints placed on the decision maker resulting from lack of information, organizational pressures,…
Theoretical model of a piezoelectric composite spinal fusion interbody implant.
Tobaben, Nicholas E; Domann, John P; Arnold, Paul M; Friis, Elizabeth A
2014-04-01
Failure rates of spinal fusion are high in smokers and diabetics. The authors are investigating the development of a piezoelectric composite biomaterial and interbody device design that could generate clinically relevant levels of electrical stimulation to help improve the rate of fusion for these patients. A lumped parameter model of the piezoelectric composite implant was developed based on a model that has been utilized to successfully predict power generation for piezoceramics. Seven variables (fiber material, matrix material, fiber volume fraction, fiber aspect ratio, implant cross-sectional area, implant thickness, and electrical load resistance) were parametrically analyzed to determine their effects on power generation within reasonable implant constraints. Influences of implant geometry and fiber aspect ratio were independent of material parameters. For a cyclic force of constant magnitude, implant thickness was directly and cross-sectional area inversely proportional to power generation potential. Fiber aspect ratios above 30 yielded maximum power generation potential while volume fractions above 15% showed superior performance. This investigation demonstrates the feasibility of using composite piezoelectric biomaterials in medical implants to generate therapeutic levels of direct current electrical stimulation. The piezoelectric spinal fusion interbody implant shows promise for helping increase success rates of spinal fusion.
a Theoretical Model of a Superheated Liquid Droplet Neutron Detector.
Harper, Mark Joseph
Neutrons can interact with the atoms in superheated liquid droplets which are suspended in a viscous matrix material, resulting in the formation of charged recoil ions. These ions transfer energy to the liquid, sometimes resulting in the droplets vaporizing and producing observable bubbles. Devices employing this mechanism are known as superheated liquid droplet detectors, or bubble detectors. The basis of bubble detector operation is identical to that of bubble chambers, which have been well characterized by researchers such as Wilson, Glaser, Seitz, and others since the 1950's. Each of the microscopic superheated liquid droplets behaves like an independent bubble chamber. This dissertation presents a theoretical model which considers the three principal aspects of detector operation: nuclear reactions, charged particle energy deposition, and thermodynamic bubble formation. All possible nuclear reactions were examined and those which could reasonably result in recoil ions sufficiently energetic to vaporize a droplet were analyzed in detail. Feasible interactions having adequate cross sections include elastic and inelastic scattering, n-proton, and n-alpha reactions. Ziegler's TRansport of Ions in Matter (TRIM) code was used to calculate the ions' stopping powers in various compounds based on the ionic energies predicted by standard scattering distributions. If the ions deposit enough energy in a small enough volume then the entire droplet will vaporize without further energy input. Various theories as to the vaporization of droplets by ionizing radiation were studied and a novel method of predicting the critical (minimum) energy was developed. This method can be used to calculate the minimum required stopping power for the ion, from which the threshold neutron energy is obtainable. Experimental verification of the model was accomplished by measuring the response of two different types of bubble detectors to monoenergetic thermal neutrons, as well as to neutrons
Models in Educational Administration: Revisiting Willower's "Theoretically Oriented" Critique
Newton, Paul; Burgess, David; Burns, David P.
2010-01-01
Three decades ago, Willower (1975) argued that much of what we take to be theory in educational administration is in fact only theoretically oriented. If we accept Willower's assessment of the field as true, what implications does this statement hold for the academic study and practical application of the theoretically oriented aspects of our…
Extraction of the relevant delays for temporal modeling
Goutte, Cyril
2000-01-01
When modeling temporal processes, just like in pattern recognition, selecting the optimal number of inputs is of central concern. We take advantage of specific features of temporal modeling to propose a novel method for extracting the inputs that attempts to yield the best predictive performance....... The method relies on the use of estimators of the generalization error to assess the predictive performance of the model. This technique is first applied to time series processing, where we perform a number of experiments on synthetic data, as well as a real life dataset, and compare the results...
Rütten, A; Röger, U; Abu-Omar, K; Frahsa, A
2009-09-01
Models explaining the engagement of organizations in different policy sectors in health promotion policy implementation often utilize retrospective data. The current study attempted to model determinants of organizational readiness (goals, resources, obligation, opportunities) in supporting health policy implementation prospectively. Twenty qualitative interviews with representatives of organizations from different policy sectors, levels of government and organizational legal entities were conducted at the beginning of a project for the promotion of physical activity among women in difficult life situations. Organizational support in developing, implementing and disseminating the project was documented over 36 months. Results indicated that in most organizations, determinants were not favorable for health promotion policy action for physical activity among women in difficult life situations. Six organizations did not report any favorable determinant, and two organizations reported four. The other 12 organizations reported positive results for some of the determinants. Project work received support from 6 out of the 20 organizations. A case study of three organizations indicated that engagement or disengagement of organizations in health promotion policy actions might be partly explained by the theoretical model. The prospective assessment of organizational readiness in implementing health promotion policy is highly relevant for health promotion. Considering the proposed theoretical framework may aid in advancing our understanding of factors that are related to organizational engagement in health promotion actions.
Theoretical model of superconducting spintronic SIsFS devices
Bakurskiy, S. V.; Klenov, N. V.; Soloviev, I. I.; Bol'ginov, V. V.; Ryazanov, V. V.; Vernik, I. V.; Mukhanov, O. A.; Kupriyanov, M. Yu.; Golubov, A. A.
2013-05-01
Motivated by recent progress in the development of cryogenic memory compatible with single flux quantum (SFQ) circuits, we have performed a theoretical study of magnetic SIsFS Josephson junctions, where "S" is a bulk superconductor, "s" is a thin superconducting film, "F" is a metallic ferromagnet, and "I" is an insulator. We calculate the Josephson current as a function of s and F layers thickness, temperature, and exchange energy of F film. We outline several modes of operation of these junctions and demonstrate their unique ability to have large product of a critical current IC and a normal-state resistance RN in the π state, comparable to that in superconductor-insulator-superconductor tunnel junctions commonly used in SFQ circuits. We develop a model describing switching of the Josephson critical current in these devices by external magnetic field. The results are in good agreement with the experimental data for Nb-Al/AlOx-Nb-Pd0.99Fe0.01-Nb junctions.
Shannon, R J; Caravan, R L; Blitz, M A; Heard, D E
2014-02-28
The kinetics of the reactions of the hydroxyl radical (OH) with acetone and dimethyl ether (DME) have been studied between 63-148 K and at a range of pressures using laser-flash photolysis coupled with laser induced fluorescence detection of OH in a pulsed Laval nozzle apparatus. For acetone, a large negative temperature dependence was observed, with the rate coefficient increasing from k1 = (1.6 ± 0.8) × 10(-12) cm(3) molecule(-1) s(-1) at 148 K to (1.0 ± 0.1) × 10(-10) cm(3) molecule(-1) s(-1) at 79 K, and also increasing with pressure. For DME, a similar behaviour was found, with the rate coefficient increasing from k2 = (3.1 ± 0.5) × 10(-12) cm(3) molecule(-1) s(-1) at 138 K to (1.7 ± 0.1) × 10(-11) cm(3) molecule(-1) s(-1) at 63 K, and also increasing with pressure. The temperature and pressure dependence of the experimental rate coefficients are rationalised for both reactions by the formation and subsequent stabilisation of a hydrogen bonded complex, with a non-zero rate coefficient extrapolated to zero pressure supportive of quantum mechanical tunnelling on the timescale of the experiments leading to products. In the case of DME, experiments performed in the presence of O2 provide additional evidence that the yield of the CH3OCH2 abstraction product, which can recycle OH in the presence of O2, is ≥50%. The experimental data are modelled using the MESMER (Master Equation Solver for Multi Energy Well Reactions) code which includes a treatment of quantum mechanical tunnelling, and uses energies and structures of transition states and complexes calculated by ab initio methods. Good agreement is seen between experiment and theory, with MESMER being able to reproduce for both reactions the temperature behaviour between ~70-800 K and the pressure dependence observed at ~80 K. At the limit of zero pressure, the model predicts a rate coefficient of ~10(-11) cm(3) molecule(-1) s(-1) for the reaction of OH with acetone at 20 K, providing evidence that the
Theoretical Modeling of ISO Results on Planetary Nebula NGC 7027
Yan, M.; Federman, S. R.; Dalgarno, A.; Bjorkman, J. E.
1999-04-01
We present a thermal and chemical model of the neutral envelope of planetary nebula NGC 7027. In our model, the neutral envelope is composed of a thin dense shell of constant density and an outer stellar wind region with the usual inverse-square law density profile. The thermal and chemical structure is calculated with the assumption that the incident radiation field on the inner surface equals 0.5×105 times Draine's fit to the average interstellar far-ultraviolet field. The rate coefficient for H2 formation on grains is assumed to be 1/5 the usual value to take into account the lower dust-gas mass ratio in the neutral envelope of NGC 7027. The calculated temperature in the dense shell decreases from 3000 to under 200 K. Once the temperature drops to 200 K, we assume that it remains at 200 K until the outer edge of the dense shell is reached, so that the observed intensities of CO J=16-15, 15-14, and 14-13 lines can be reproduced. The 200 K temperature can be interpreted as the average temperature of the shocked gas just behind the forward shock front in the framework of the interacting stellar wind theory. We calculate the intensities of the molecular far-infrared rotational lines by using a revised version of the escape probability formalism. The theoretical intensities for rotational lines of CO (from J=29-28 to J=14-13), CH+, OH, and CH are shown to be in good agreement with ISO observations. The H2 rovibrational line intensities are also calculated and are in agreement with available observations.
Macroscale hydrologic modeling of ecologically relevant flow metrics
Seth J. Wenger; Charles H. Luce; Alan F. Hamlet; Daniel J. Isaak; Helen M. Neville
2010-01-01
Stream hydrology strongly affects the structure of aquatic communities. Changes to air temperature and precipitation driven by increased greenhouse gas concentrations are shifting timing and volume of streamflows potentially affecting these communities. The variable infiltration capacity (VIC) macroscale hydrologic model has been employed at regional scales to describe...
Safety-relevant mode confusions-modelling and reducing them
Bredereke, Jan [Universitaet Bremen, FB 3, P.O. Box 330 440, D-28334 Bremen (Germany)]. E-mail: brederek@tzi.de; Lankenau, Axel [Universitaet Bremen, FB 3, P.O. Box 330 440, D-28334 Bremen (Germany)
2005-06-01
Mode confusions are a significant safety concern in safety-critical systems, for example in aircraft. A mode confusion occurs when the observed behaviour of a technical system is out of sync with the user's mental model of its behaviour. But the notion is described only informally in the literature. We present a rigorous way of modelling the user and the machine in a shared-control system. This enables us to propose precise definitions of 'mode' and 'mode confusion' for safety-critical systems. We then validate these definitions against the informal notions in the literature. A new classification of mode confusions by cause leads to a number of design recommendations for shared-control systems. These help in avoiding mode confusion problems. Our approach supports the automated detection of remaining mode confusion problems. We apply our approach practically to a wheelchair robot.
An ecologically relevant guinea pig model of fetal behavior.
Bellinger, S A; Lucas, D; Kleven, G A
2015-04-15
The laboratory guinea pig, Cavia porcellus, shares with humans many similarities during pregnancy and prenatal development, including precocial offspring and social dependence. These similarities suggest the guinea pig as a promising model of fetal behavioral development as well. Using innovative methods of behavioral acclimation, fetal offspring of female IAF hairless guinea pigs time mated to NIH multicolored Hartley males were observed longitudinally without restraint using noninvasive ultrasound at weekly intervals across the 10 week gestation. To ensure that the ultrasound procedure did not cause significant stress, salivary cortisol was collected both before and after each observation. Measures of fetal spontaneous movement and behavioral state were quantified from video recordings from week 3 through the last week before birth. Results from prenatal quantification of Interlimb Movement Synchrony and state organization reveal guinea pig fetal development to be strikingly similar to that previously reported for other rodents and preterm human infants. Salivary cortisol readings taken before and after sonography did not differ at any observation time point. These results suggest this model holds translational promise for studying the prenatal mechanisms of neurobehavioral development, including those that may result from adverse events. Because the guinea pig is a highly social mammal with a wide range of socially oriented vocalizations, this model may also have utility for studying the prenatal origins and trajectories of developmental disabilities with social-emotional components, such as autism.
Mechanical Relaxation of Metallic Glasses: An Overview of Experimental Data and Theoretical Models
Chaoren Liu
2015-06-01
Full Text Available Relaxation phenomena in glasses are a subject of utmost interest, as they are deeply connected with their structure and dynamics. From a theoretical point of view, mechanical relaxation allows one to get insight into the different atomic-scale processes taking place in the glassy state. Focusing on their possible applications, relaxation behavior influences the mechanical properties of metallic glasses. This paper reviews the present knowledge on mechanical relaxation of metallic glasses. The features of primary and secondary relaxations are reviewed. Experimental data in the time and frequency domain is presented, as well as the different models used to describe the measured relaxation spectra. Extended attention is paid to dynamic mechanical analysis, as it is the most important technique allowing one to access the mechanical relaxation behavior. Finally, the relevance of the relaxation behavior in the mechanical properties of metallic glasses is discussed.
A Theoretical Model for Digital Reverberations of City Spaces and Public Places
Zimmerman, Chris; Hansen, Kjeld; Vatrapu, Ravi
2014-01-01
The increasing pervasiveness of Internet connected devices and services is altering the perception and practice of public spaces through the provisioning of location-specific digital information. Location-aware technologies allow people to access, annotate, address and attach information...... and Mobile technologies that describe and explain crowd-sourced socio-technical layers on the city landscape. The proposed integrated theoretical model describes the relevant information linkages between people and places in the online and offline worlds and introduces a new evaluation method...... for the evaluation of city places: affinity spectrum of social endorsements. The authors conclude with a discussion of the new opportunities for governments to better understand socially emergent ‘urban qualities’ and how citizens construct and appreciate them in order better convert city places into public spaces....
Relevant Aspects in Modeling of Micro-injection Molding
Nguyen-Chung, Tham; Jüttner, Gábor; Pham, Tung; Mennig, Günter
2008-07-01
Growing demands in the manufacturing of micro and precision components in plastics require new concepts for molding machines and micro molds on the one hand. On the other hand, a deeper understanding of the filling and solidification process in a micro mold is indispensable. In this work, the filling process of a micro spiral was analyzed by modeling the compressible flow using pressure dependent viscosity and adjusted heat transfer coefficients. At the same time, experimental filling studies were carried out on an accurately controlled micro-injection molding machine. Based on the relationship between the injection pressure and the filling degree, essential factors for the quality of the simulation can be identified. It can be shown that the flow behavior of the melt in a micro cavity of high aspect ratio is extremely dependent on the melt compressibility in the injection cylinder which needs to be considered in the simulation in order to predict an accurate flow rate. Moreover, the heat transfer coefficients between the melt and the mold wall vary significantly when changing cavity thickness and processing conditions. It is believed that a pressure dependent model for the heat transfer coefficient would be able to improve the quality of the process simulation.
Carcinogenically relevant split dose repair increased with age in rat skin model.
Burns, Fredric; Tang, Moon-Shong Eric; Wu, Feng; Uddin, Ahmed
2012-07-01
These experiments utilize cancer induction to evaluate cancer-relevant repair during the interval between dose fractions. Low LET electron radiation(LET ~ 0.34 keV/u) were utilized in experiments that involved exposing rat dorsal skin to 2 equal 8 Gy dose fractions separated at various intervals from 0.25 h to 24 h. Cancer onset was established for 80 weeks after the exposures and only histologically verified cancers were included in the analysis. This experiment involved a total of 540 rats and 880 induced cancers. In the youngest rats (irradiated at 28 days of age) the cancer yield declined with a halftime of approximately 3.5 hrs. In 113 day old rats the cancer yield halftime was shortened to 1.3 hrs. In the oldest rats (182 days of age), the halftime could not be established quantitatively, because it was less than the shortest interval (15 min) utilized in the protocol (best estimate ~5 min). In the oldest rats the cancer yields for all fractionated exposures dropped essentially to the expected level of 2 single fractions, below which theoretically no further reduction is possible. The follow-up times for obtaining cancer yields were the same for all exposure groups in spite of the differing ages at exposure. These results indicate that repair of carcinogenically-relevant damage accelerates with age of the rat. No information is available on the possible mechanistic basis for this finding, although the model might be useful for delineating which of the many postulated split dose repair pathways is the correct one. The finding indicates that older rats should be less susceptible to the carcinogenic action of single doses of low LET radiation in comparison to younger rats, which has been verified in separate studies.
Generalized Potts-Models and their Relevance for Gauge Theories
Andreas Wipf
2007-01-01
Full Text Available We study the Polyakov loop dynamics originating from finite-temperature Yang-Mills theory. The effective actions contain center-symmetric terms involving powers of the Polyakov loop, each with its own coupling. For a subclass with two couplings we perform a detailed analysis of the statistical mechanics involved. To this end we employ a modified mean field approximation and Monte Carlo simulations based on a novel cluster algorithm. We find excellent agreement of both approaches. The phase diagram exhibits both first and second order transitions between symmetric, ferromagnetic and antiferromagnetic phases with phase boundaries merging at three tricritical points. The critical exponents ν and γ at the continuous transition between symmetric and antiferromagnetic phases are the same as for the 3-state spin Potts model.
Dust from AGBs: relevant factors and modelling uncertainties
Ventura, P; Schneider, R; Di Criscienzo, M; Rossi, C; La Franca, F; Gallerani, S; Valiante, R
2014-01-01
The dust formation process in the winds of Asymptotic Giant Branch stars is discussed, based on full evolutionary models of stars with mass in the range $1$M$_{\\odot} \\leq$M$\\leq 8$M$_{\\odot}$, and metallicities $0.001 < Z <0.008$. Dust grains are assumed to form in an isotropically expanding wind, by growth of pre--existing seed nuclei. Convection, for what concerns the treatment of convective borders and the efficiency of the schematization adopted, turns out to be the physical ingredient used to calculate the evolutionary sequences with the highest impact on the results obtained. Low--mass stars with M$\\leq 3$M$_{\\odot}$ produce carbon type dust with also traces of silicon carbide. The mass of solid carbon formed, fairly independently of metallicity, ranges from a few $10^{-4}$M$_{\\odot}$, for stars of initial mass $1-1.5$M$_{\\odot}$, to $\\sim 10^{-2}$M$_{\\odot}$ for M$\\sim 2-2.5$M$_{\\odot}$; the size of dust particles is in the range $0.1 \\mu$m$\\leq a_C \\leq 0.2\\mu$m. On the contrary, the production...
Imaging of a clinically relevant stroke model: glucose hypermetabolism revisited.
Arnberg, Fabian; Grafström, Jonas; Lundberg, Johan; Nikkhou-Aski, Sahar; Little, Philip; Damberg, Peter; Mitsios, Nicholas; Mulder, Jan; Lu, Li; Söderman, Michael; Stone-Elander, Sharon; Holmin, Staffan
2015-03-01
Ischemic stroke has been shown to cause hypermetabolism of glucose in the ischemic penumbra. Experimental and clinical data indicate that infarct-related systemic hyperglycemia is a potential therapeutic target in acute stroke. However, clinical studies aiming for glucose control in acute stroke have neither improved functional outcome nor reduced mortality. Thus, further studies on glucose metabolism in the ischemic brain are warranted. We used a rat model of stroke that preserves collateral flow. The animals were analyzed by [2-(18)F]-2-fluoro-2-deoxy-d-glucose positron emission tomography or magnetic resonance imaging during 90-minute occlusion of the middle cerebral artery and during 60 minutes after reperfusion. Results were correlated to magnetic resonance imaging of cerebral blood flow, diffusion of water, lactate formation, and histological data on cell death and blood-brain barrier breakdown. We detected an increased [2-(18)F]-2-fluoro-2-deoxy-d-glucose uptake within ischemic regions succumbing to infarction and in the peri-infarct region. Magnetic resonance imaging revealed impairment of blood flow to ischemic levels in the infarct and a reduction of cerebral blood flow in the peri-infarct region. Magnetic resonance spectroscopy revealed lactate in the ischemic region and absence of lactate in the peri-infarct region. Immunohistochemical analyses revealed apoptosis and blood-brain barrier breakdown within the infarct. The increased uptake of [2-(18)F]-2-fluoro-2-deoxy-d-glucose in cerebral ischemia most likely reflects hypermetabolism of glucose meeting increased energy needs of ischemic and hypoperfused brain tissue, and it occurs under both anaerobic and aerobic conditions measured by local lactate production. Infarct-related systemic hyperglycemia could serve to facilitate glucose supply to the ischemic brain. Glycemic control by insulin treatment could negatively influence this mechanism. © 2015 American Heart Association, Inc.
Toxicity of food-relevant nanoparticles in intestinal epithelial models
McCracken, Christie
Nanoparticles are increasingly being incorporated into common consumer products, including in foods and food packaging, for their unique properties at the nanoscale. Food-grade silica and titania are used as anti-caking and whitening agents, respectively, and these particle size distributions are composed of approximately one-third nanoparticles. Zinc oxide and silver nanoparticles can be used for their antimicrobial properties. However, little is known about the interactions of nanoparticles in the body upon ingestion. This study was performed to investigate the role of nanoparticle characteristics including surface chemistry, dissolution, and material type on toxicity to the intestinal epithelium. Only mild acute toxicity of zinc oxide nanoparticles was observed after 24-hour treatment of intestinal epithelial C2BBe1 cells based on the results of toxicity assays measuring necrosis, apoptosis, membrane damage, and mitochondrial activity. Silica and titanium dioxide nanoparticles were not observed to be toxic although all nanoparticles were internalized by cells. In vitro digestion of nanoparticles in solutions representing the stomach and intestines prior to treatment of cells did not alter nanoparticle toxicity. Long-term repeated treatment of cells weekly for 24 hours with nanoparticles did not change nanoparticle cytotoxicity or the growth rate of the treated cell populations. Thus, silica, titanium dioxide, and zinc oxide nanoparticles were found to induce little toxicity in intestinal epithelial cells. Fluorescent silica nanoparticles were synthesized as a model for silica used in foods that could be tracked in vitro and in vivo. To maintain an exterior of pure silica, a silica shell was hydrolyzed around a core particle of quantum dots or a fluorescent dye electrostatically associated with a commercial silica particle. The quantum dots used were optimized from a previously reported microwave quantum dot synthesis to a quantum yield of 40%. Characterization
Ultrafast Structural Dynamics in Combustion Relevant Model Systems
Weber, Peter M. [Brown University
2014-03-31
The research project explored the time resolved structural dynamics of important model reaction system using an array of novel methods that were developed specifically for this purpose. They include time resolved electron diffraction, time resolved relativistic electron diffraction, and time resolved Rydberg fingerprint spectroscopy. Toward the end of the funding period, we also developed time-resolved x-ray diffraction, which uses ultrafast x-ray pulses at LCLS. Those experiments are just now blossoming, as the funding period expired. In the following, the time resolved Rydberg Fingerprint Spectroscopy is discussed in some detail, as it has been a very productive method. The binding energy of an electron in a Rydberg state, that is, the energy difference between the Rydberg level and the ground state of the molecular ion, has been found to be a uniquely powerful tool to characterize the molecular structure. To rationalize the structure sensitivity we invoke a picture from electron diffraction: when it passes the molecular ion core, the Rydberg electron experiences a phase shift compared to an electron in a hydrogen atom. This phase shift requires an adjustment of the binding energy of the electron, which is measurable. As in electron diffraction, the phase shift depends on the molecular, geometrical structure, so that a measurement of the electron binding energy can be interpreted as a measurement of the molecule’s structure. Building on this insight, we have developed a structurally sensitive spectroscopy: the molecule is first elevated to the Rydberg state, and the binding energy is then measured using photoelectron spectroscopy. The molecule’s structure is read out as the binding energy spectrum. Since the photoionization can be done with ultrafast laser pulses, the technique is inherently capable of a time resolution in the femtosecond regime. For the purpose of identifying the structures of molecules during chemical reactions, and for the analysis of
Ultrafast Structural Dynamics in Combustion Relevant Model Systems
Weber, Peter M. [Brown University
2014-03-31
The research project explored the time resolved structural dynamics of important model reaction system using an array of novel methods that were developed specifically for this purpose. They include time resolved electron diffraction, time resolved relativistic electron diffraction, and time resolved Rydberg fingerprint spectroscopy. Toward the end of the funding period, we also developed time-resolved x-ray diffraction, which uses ultrafast x-ray pulses at LCLS. Those experiments are just now blossoming, as the funding period expired. In the following, the time resolved Rydberg Fingerprint Spectroscopy is discussed in some detail, as it has been a very productive method. The binding energy of an electron in a Rydberg state, that is, the energy difference between the Rydberg level and the ground state of the molecular ion, has been found to be a uniquely powerful tool to characterize the molecular structure. To rationalize the structure sensitivity we invoke a picture from electron diffraction: when it passes the molecular ion core, the Rydberg electron experiences a phase shift compared to an electron in a hydrogen atom. This phase shift requires an adjustment of the binding energy of the electron, which is measurable. As in electron diffraction, the phase shift depends on the molecular, geometrical structure, so that a measurement of the electron binding energy can be interpreted as a measurement of the molecule’s structure. Building on this insight, we have developed a structurally sensitive spectroscopy: the molecule is first elevated to the Rydberg state, and the binding energy is then measured using photoelectron spectroscopy. The molecule’s structure is read out as the binding energy spectrum. Since the photoionization can be done with ultrafast laser pulses, the technique is inherently capable of a time resolution in the femtosecond regime. For the purpose of identifying the structures of molecules during chemical reactions, and for the analysis of
Presenting a Theoretical Model of Four Conceptions of Civic Education
Cohen, Aviv
2010-01-01
This conceptual study will question the ways different epistemological conceptions of citizenship and education influence the characteristics of civic education. While offering a new theoretical framework, the different undercurrent conceptions that lay at the base of the civic education process shall be brought forth. With the use of the method…
Determining Student Competency in Field Placements: An Emerging Theoretical Model
Twyla L. Salm
2016-06-01
Full Text Available This paper describes a qualitative case study that explores how twenty-three field advisors, representing three human service professions including education, nursing, and social work, experience the process of assessment with students who are struggling to meet minimum competencies in field placements. Five themes emerged from the analysis of qualitative interviews. The field advisors primary concern was the level of professional competency achieved by practicum students. Related to competency were themes concerned with the field advisor's role in being accountable and protecting the reputation of his/her profession as well as the reputation of the professional program affiliated with the practicum student's professional education. The final theme – teacher-student relationship –emerged from the data, both as a stand-alone and global or umbrella theme. As an umbrella theme, teacher-student relationship permeated each of the other themes as the participants interpreted their experiences of the process of assessment through the mentor relationships. A theoretical model was derived from these findings and the description of the model is presented. Cet article décrit une étude de cas qualitative qui explore comment vingt-trois conseillers de stages, représentant trois professions de services sociaux comprenant l’éducation, les soins infirmiers et le travail social, ont vécu l’expérience du processus d’évaluation avec des étudiants qui ont des difficultés à acquérir les compétences minimales durant les stages. Cinq thèmes ont été identifiés lors de l’analyse des entrevues qualitatives. La préoccupation principale des conseillers de stages était le niveau de compétence professionnelle acquis par les stagiaires. Les thèmes liés à la compétence étaient le rôle des conseillers de stages dans leur responsabilité pour protéger la réputation de leur profession ainsi que la réputation d’un programme professionnel
A User-Centered Approach to Adaptive Hypertext Based on an Information Relevance Model
Mathe, Nathalie; Chen, James
1994-01-01
Rapid and effective to information in large electronic documentation systems can be facilitated if information relevant in an individual user's content can be automatically supplied to this user. However most of this knowledge on contextual relevance is not found within the contents of documents, it is rather established incrementally by users during information access. We propose a new model for interactively learning contextual relevance during information retrieval, and incrementally adapting retrieved information to individual user profiles. The model, called a relevance network, records the relevance of references based on user feedback for specific queries and user profiles. It also generalizes such knowledge to later derive relevant references for similar queries and profiles. The relevance network lets users filter information by context of relevance. Compared to other approaches, it does not require any prior knowledge nor training. More importantly, our approach to adaptivity is user-centered. It facilitates acceptance and understanding by users by giving them shared control over the adaptation without disturbing their primary task. Users easily control when to adapt and when to use the adapted system. Lastly, the model is independent of the particular application used to access information, and supports sharing of adaptations among users.
Taormina, R.; Galelli, S.; Karakaya, G.; Ahipasaoglu, S. D.
2016-11-01
This work investigates the uncertainty associated to the presence of multiple subsets of predictors yielding data-driven models with the same, or similar, predictive accuracy. To handle this uncertainty effectively, we introduce a novel input variable selection algorithm, called Wrapper for Quasi Equally Informative Subset Selection (W-QEISS), specifically conceived to identify all alternate subsets of predictors in a given dataset. The search process is based on a four-objective optimization problem that minimizes the number of selected predictors, maximizes the predictive accuracy of a data-driven model and optimizes two information theoretic metrics of relevance and redundancy, which guarantee that the selected subsets are highly informative and with little intra-subset similarity. The algorithm is first tested on two synthetic test problems and then demonstrated on a real-world streamflow prediction problem in the Yampa River catchment (US). Results show that complex hydro-meteorological datasets are characterized by a large number of alternate subsets of predictors, which provides useful insights on the underlying physical processes. Furthermore, the presence of multiple subsets of predictors-and associated models-helps find a better trade-off between different measures of predictive accuracy commonly adopted for hydrological modelling problems.
Chen, Yun; Yang, Hui
2016-12-01
In the era of big data, there are increasing interests on clustering variables for the minimization of data redundancy and the maximization of variable relevancy. Existing clustering methods, however, depend on nontrivial assumptions about the data structure. Note that nonlinear interdependence among variables poses significant challenges on the traditional framework of predictive modeling. In the present work, we reformulate the problem of variable clustering from an information theoretic perspective that does not require the assumption of data structure for the identification of nonlinear interdependence among variables. Specifically, we propose the use of mutual information to characterize and measure nonlinear correlation structures among variables. Further, we develop Dirichlet process (DP) models to cluster variables based on the mutual-information measures among variables. Finally, orthonormalized variables in each cluster are integrated with group elastic-net model to improve the performance of predictive modeling. Both simulation and real-world case studies showed that the proposed methodology not only effectively reveals the nonlinear interdependence structures among variables but also outperforms traditional variable clustering algorithms such as hierarchical clustering.
Chen, Yun; Yang, Hui
2016-12-14
In the era of big data, there are increasing interests on clustering variables for the minimization of data redundancy and the maximization of variable relevancy. Existing clustering methods, however, depend on nontrivial assumptions about the data structure. Note that nonlinear interdependence among variables poses significant challenges on the traditional framework of predictive modeling. In the present work, we reformulate the problem of variable clustering from an information theoretic perspective that does not require the assumption of data structure for the identification of nonlinear interdependence among variables. Specifically, we propose the use of mutual information to characterize and measure nonlinear correlation structures among variables. Further, we develop Dirichlet process (DP) models to cluster variables based on the mutual-information measures among variables. Finally, orthonormalized variables in each cluster are integrated with group elastic-net model to improve the performance of predictive modeling. Both simulation and real-world case studies showed that the proposed methodology not only effectively reveals the nonlinear interdependence structures among variables but also outperforms traditional variable clustering algorithms such as hierarchical clustering.
Present status on atomic and molecular data relevant to fusion plasma diagnostics and modeling
Tawara, H. [ed.
1997-01-01
This issue is the collection of the paper presented status on atomic and molecular data relevant to fusion plasma diagnostics and modeling. The 10 of the presented papers are indexed individually. (J.P.N.)
Rodríguez, J; Clemente, G; Sanjuán, N; Bon, J
2014-01-01
The drying kinetics of thyme was analyzed by considering different conditions: air temperature of between 40°C and 70°C , and air velocity of 1 m/s. A theoretical diffusion model and eight different empirical models were fitted to the experimental data. From the theoretical model application, the effective diffusivity per unit area of the thyme was estimated (between 3.68 × 10(-5) and 2.12 × 10 (-4) s(-1)). The temperature dependence of the effective diffusivity was described by the Arrhenius relationship with activation energy of 49.42 kJ/mol. Eight different empirical models were fitted to the experimental data. Additionally, the dependence of the parameters of each model on the drying temperature was determined, obtaining equations that allow estimating the evolution of the moisture content at any temperature in the established range. Furthermore, artificial neural networks were developed and compared with the theoretical and empirical models using the percentage of the relative errors and the explained variance. The artificial neural networks were found to be more accurate predictors of moisture evolution with VAR ≥ 99.3% and ER ≤ 8.7%.
Surge motion of an ice floe in waves: comparison of theoretical and experimental models
Meylan, Michael; Bennetts, Luke; French, Benjamin; Thomas, Giles
2014-01-01
A theoretical model and an experimental model of surge motions of an ice floe due to regular waves are presented. The theoretical model is a modified version of Morrison's equation, valid for small floating bodies. The experimental model is implemented in a wave basin at scale 1:100, using a thin plastic disk to model the floe. The processed experimental data displays a regime change in surge amplitude when the incident wavelength is approximately twice the floe diameter. It is shown that the theoretical model is accurate in the large wavelength regime, but highly inaccurate for the small wavelength regime.
Theoretical models of ferromagnetic III-V semiconductors
Jungwirth, T.; Sinova, Jairo; Kučera, J.; MacDonald, A. H.
2002-01-01
Recent materials research has advanced the maximum ferromagnetic transition temperature in semiconductors containing magnetic elements toward room temperature. Reaching this goal would make information technology applications of these materials likely. In this article we briefly review the status of work over the past five years which has attempted to achieve a theoretical understanding of these complex magnetic systems. The basic microscopic origins of ferromagnetism in the (III,Mn)V compoun...
Theoretical modeling of orientational effects in liquid-crystal layers
Melnikova, E. A.
2005-11-01
In the work the approximate analytical relations describing the director distribution in depth of a plane-parallel layer of nematic liquid crystal are presented. The analytical expression determining the orientational effect of the periodic surface in a system "relief grating - liquid crystal" is derived. Its diffraction characteristics are studied theoretically. Relaxation kinetics of the director in a plane-parallel layer of nematic liquid crystal is considered taking account of the microscopic inertia moment.
Pinnapureddy, Ashish R; Stayner, Cherie; McEwan, John; Baddeley, Olivia; Forman, John; Eccles, Michael R
2015-09-02
Animals that accurately model human disease are invaluable in medical research, allowing a critical understanding of disease mechanisms, and the opportunity to evaluate the effect of therapeutic compounds in pre-clinical studies. Many types of animal models are used world-wide, with the most common being small laboratory animals, such as mice. However, rodents often do not faithfully replicate human disease, despite their predominant use in research. This discordancy is due in part to physiological differences, such as body size and longevity. In contrast, large animal models, including sheep, provide an alternative to mice for biomedical research due to their greater physiological parallels with humans. Completion of the full genome sequences of many species, and the advent of Next Generation Sequencing (NGS) technologies, means it is now feasible to screen large populations of domesticated animals for genetic variants that resemble human genetic diseases, and generate models that more accurately model rare human pathologies. In this review, we discuss the notion of using sheep as large animal models, and their advantages in modelling human genetic disease. We exemplify several existing naturally occurring ovine variants in genes that are orthologous to human disease genes, such as the Cln6 sheep model for Batten disease. These, and other sheep models, have contributed significantly to our understanding of the relevant human disease process, in addition to providing opportunities to trial new therapies in animals with similar body and organ size to humans. Therefore sheep are a significant species with respect to the modelling of rare genetic human disease, which we summarize in this review.
Elvik, Rune
2015-11-01
This paper probes the relationship between changes in the risk of apprehension for speeding in Norway and changes in the amount of speeding. The paper is based on a game-theoretic model of how the rate of violations and the amount of enforcement is determined by the interaction between drivers and the police. This model makes predictions both about how drivers will adapt to changes in the amount of enforcement (the more enforcement, the less violations) as well as how the police will adapt to changes in the rate of violations (the less violations, the less enforcement). The paper attempts to test the game-theoretic model empirically. Testing the model rigorously is difficult, mainly because some of the relevant variables are not reliably measured and are endogenous. Two models were developed: one to identify sources of changes in the rate of violations, one to identify sources of changes in the amount of enforcement. The predictions of the game-theoretic model were supported, although the results were not statistically significant in the model of how the police adapt enforcement to changes in the rate of violations.
Theoretical Modeling and Electromagnetic Response of Complex Metamaterials
2017-03-06
and Nanocavity,” ACS Photonics, Vol. 2, No. 8, pp. 1000-1006, August 27, 2015. DISTRIBUTION A: Distribution approved for public release. J34. R...Reflection,” ACS Photonics, Vol. 4, No. 2, pp. 228-235, February 23, 2017. DISTRIBUTION A: Distribution approved for public release. Relevant patent...Report 03/06/2017 DISTRIBUTION A: Distribution approved for public release. AF Office Of Scientific Research (AFOSR)/ RTB1 Arlington, Virginia 22203
Andersen, Karsten Brandt; Levinsen, Simon; Svendsen, Winnie Edith;
2009-01-01
In this article we present a generalized theoretical model for the continuous separation of particles using the pinched flow fractionation method. So far the theoretical models have not been able to predict the separation of particles without the use of correction factors. In this article we pres...
Dziedziewicz, Dorota; Karwowski, Maciej
2015-01-01
This paper presents a new theoretical model of creative imagination and its applications in early education. The model sees creative imagination as composed of three inter-related components: vividness of images, their originality, and the level of transformation of imageries. We explore the theoretical and practical consequences of this new…
Zee, van der F.A.
1997-01-01
This study explores the relevance and applicability of political economy models for the explanation of agricultural policies. Part I (chapters 4-7) takes a general perspective and evaluates the empirical applicability of voting models and interest group models to agricultural policy
Zee, van der F.A.
1997-01-01
This study explores the relevance and applicability of political economy models for the explanation of agricultural policies. Part I (chapters 4-7) takes a general perspective and evaluates the empirical applicability of voting models and interest group models to agricultural policy formation in ind
Zee, van der F.A.
1997-01-01
This study explores the relevance and applicability of political economy models for the explanation of agricultural policies. Part I (chapters 4-7) takes a general perspective and evaluates the empirical applicability of voting models and interest group models to agricultural policy formati
Theoretical and practical aspects of modelling activated sludge processes
Meijer, S.C.F.
2004-01-01
This thesis describes the full-scale validation and calibration of a integrated metabolic activated sludge model for biological phosphorus removal. In chapters 1 and 2 the metabolic model is described, in chapters 3 to 6 the model is tested and in chapters 7 and 8 the model is put into practice.
Theoretical and practical aspects of modelling activated sludge processes
Meijer, S.C.F.
2004-01-01
This thesis describes the full-scale validation and calibration of a integrated metabolic activated sludge model for biological phosphorus removal. In chapters 1 and 2 the metabolic model is described, in chapters 3 to 6 the model is tested and in chapters 7 and 8 the model is put into practice. Cha
Theoretical and practical aspects of modelling activated sludge processes
Meijer, S.C.F.
2004-01-01
This thesis describes the full-scale validation and calibration of a integrated metabolic activated sludge model for biological phosphorus removal. In chapters 1 and 2 the metabolic model is described, in chapters 3 to 6 the model is tested and in chapters 7 and 8 the model is put into practice. Cha
1979-01-01
to motivate the form of the results for inelastic binary collisions characterized by an isotropic scattering cross section. For an inelastic...which are excited or ionized by the e -beam . Strictly speaking , the reverse process for reaction (101. 1) should also be included, although its...ETC F/S 20/5 THEORETICAL MODELING OF MOLECULAR AND ELECTRON KINETIC PROCESS~— efl ~ (rj)JAN 79 W B LACINA NO OO i~—78—C—Ofl9UNCLASSIFIED NRTC—79—7R
Theoretical Explanation and Improvement to the Flare Model of Lithography Based on the Kirk Test
CHEN De-Liang; CAO Yi-Ping; HUANG Zhen-Fen
2011-01-01
@@ The Kirk test has good precision for measuring stray light in optical lithography and is the usual method of measuring stray light.However, Kirk did not provide a theoretical explanation to his simulation model.We attempt to give Kirk's model a kind of theoretical explanation and a little improvement based on the model of point spread function of scattering and the theory of statistical optics.It is indicated by simulation that the improved model fits Kirk's measurement data better.
Kim, Young Rae
2013-01-01
A theoretical model of metacognition in complex modeling activities has been developed based on existing frameworks, by synthesizing the re-conceptualization of metacognition at multiple levels by looking at the three sources that trigger metacognition. Using the theoretical model as a framework, this study was designed to explore how students'…
Deferred Action: Theoretical model of process architecture design for emergent business processes
Patel, N.V.
2007-01-01
Full Text Available E-Business modelling and ebusiness systems development assumes fixed company resources, structures, and business processes. Empirical and theoretical evidence suggests that company resources and structures are emergent rather than fixed. Planning business activity in emergent contexts requires flexible ebusiness models based on better management theories and models . This paper builds and proposes a theoretical model of ebusiness systems capable of catering for emergent factors that affect business processes. Drawing on development of theories of the ‘action and design’class the Theory of Deferred Action is invoked as the base theory for the theoretical model. A theoretical model of flexible process architecture is presented by identifying its core components and their relationships, and then illustrated with exemplar flexible process architectures capable of responding to emergent factors. Managerial implications of the model are considered and the model’s generic applicability is discussed.
Ledermann, Thomas; Kenny, David A
2012-02-01
Studying dyads, very often there is a theoretical construct that has an effect on both members, such as relationship harmony or shared environment. To model such influences, the common fate model (CFM) is often the most appropriate approach. In this article, we address conceptual and statistical issues in the use of the standard CFM and present a series of variations, all of which are estimated by structural equation modeling (SEM). For indistinguishable dyad members (e.g., gay couples), we describe the use of a multilevel SEM method. Throughout the paper, we draw connections to the actor-partner interdependence model (APIM). We also discuss the analysis of hybrid models that combines both the CFM and the APIM. The models are illustrated using data from heterosexual couples.
Theoretical models for the regulation of DNA replication in fast-growing bacteria
Creutziger, Martin; Schmidt, Mischa; Lenz, Peter
2012-09-01
Growing in always changing environments, Escherichia coli cells are challenged by the task to coordinate growth and division. In particular, adaption of their growth program to the surrounding medium has to guarantee that the daughter cells obtain fully replicated chromosomes. Replication is therefore to be initiated at the right time, which is particularly challenging in media that support fast growth. Here, the mother cell initiates replication not only for the daughter but also for the granddaughter cells. This is possible only if replication occurs from several replication forks that all need to be correctly initiated. Despite considerable efforts during the last 40 years, regulation of this process is still unknown. Part of the difficulty arises from the fact that many details of the relevant molecular processes are not known. Here, we develop a novel theoretical strategy for dealing with this general problem: instead of analyzing a single model, we introduce a wide variety of 128 different models that make different assumptions about the unknown processes. By comparing the predictions of these models we are able to identify the key quantities that allow the experimental discrimination of the different models. Analysis of these quantities yields that out of the 128 models 94 are not consistent with available experimental data. From the remaining 34 models we are able to conclude that mass growth and DNA replication need either to be truly coupled, by coupling DNA replication initiation to the event of cell division, or to the amount of accumulated mass. Finally, we make suggestions for experiments to further reduce the number of possible regulation scenarios.
Theoretical model for a Faraday anomalous dispersion optical filter
Yin, B.; Shay, T. M.
1991-01-01
A model for the Faraday anomalous dispersion optical filter is presented. The model predicts a bandwidth of 0.6 GHz and a transmission peak of 0.98 for a filter operating on the Cs (D2) line. The model includes hyperfine effects and is valid for arbitrary magnetic fields.
M$^2$I Communication: From Theoretical Modeling to Practical Design
Guo, Hongzhi
2015-01-01
Wireless communications in complex environments are constrained by lossy media and complicated structures. Magnetic Induction (MI) has been proved to be an efficient solution to extend the communication range. Due to the small coil antenna's physical limitation, however, MI's communication range is still very limited. To this end, Metamaterial-enhanced Magnetic Induction (M$^2$I) communication has been proposed and the theoretical results suggest that it can significantly increase the communication performance, namely, data rate and communication range. Nevertheless, currently, the real implementation of M$^2$I is still a challenge and there is no guideline on design and fabrication of spherical metamaterial. In this paper, we propose a practical design by using a spherical coil array to realize M$^2$I and we prove that it can achieve negative permeability and there exists a resonance condition where the radiated magnetic field can be significantly amplified. The radiation and communication performance are ev...
Theoretical models for NO decomposition in Cu-exchanged zeolites
Tsekov, R
2015-01-01
A unified description of the catalytic effect of Cu-exchanged zeolites is proposed for the decomposition of NO. A general expression for the rate constant of NO decomposition is obtained by assuming that the rate-determining step consists of the transferring of a single atom associated with breaking of the N-O bond. The analysis is performed on the base of the generalized Langevin equation and takes into account both the potential interactions in the system and the memory effects due to the zeolite vibrations. Two different mechanisms corresponding to monomolecular and bimolecular NO decomposition are discussed. The catalytic effect in the monomolecular mechanism is related to both the Cu+ ions and zeolite O-vacancies, while in the case of the bimolecular mechanism the zeolite contributes through dissipation only. The comparison of the theoretically calculated rate constants with experimental results reveals additional information about the geometric and energetic characteristics of the active centers and con...
A graph theoretical perspective of a drug abuse epidemic model
Nyabadza, F.; Mukwembi, S.; Rodrigues, B. G.
2011-05-01
A drug use epidemic can be represented by a finite number of states and transition rules that govern the dynamics of drug use in each discrete time step. This paper investigates the spread of drug use in a community where some users are in treatment and others are not in treatment, citing South Africa as an example. In our analysis, we consider the neighbourhood prevalence of each individual, i.e., the proportion of the individual’s drug user contacts who are not in treatment amongst all of his or her contacts. We introduce parameters α∗, β∗ and γ∗, depending on the neighbourhood prevalence, which govern the spread of drug use. We examine how changes in α∗, β∗ and γ∗ affect the system dynamics. Simulations presented support the theoretical results.
The theoretical foundations for size spectrum models of fish communities
Andersen, Ken Haste; Jacobsen, Nis Sand; Farnsworth, K.D.
2016-01-01
assessment of fisheries. We describe the fundamental concepts in size-based models about food encounter and the bioenergetics budget of individuals. Within the general framework three model types have emerged that differs in their degree of complexity: the food-web, the trait-based and the community model....... We demonstrate the differences between the models through examples of their response to fishing and their dynamic behavior. We review implementations of size spectrum models and describe important variations concerning the functional response, whether growth is food-dependent or fixed...
Theoretical and experimental modeling of a rail gun accelerator
Zheleznyj, V. B.; Zagorskij, A. V.; Katsnel'Son, S. S.; Kudryavtsev, A. V.; Plekhanov, A. V.
1993-04-01
Results of a series of experiments in the acceleration of macrobodies are analyzed using an integral model of a current arc and a quasi-1D magnetic gasdynamic model. The integral model uses gasdynamic equations averaged by the size of a plasma pump and equations based on the second Kirchhoff's law for electrical current. The quasi-1D model is based on 1D magnetic gasdynamic equations for mean values of density, pressure, velocity, and internal power. Electromagnetic parameters are determined from Maxwell integral equations. It is concluded that the proposed models take into account the major mechanisms of momentum loss and are capable of adequately describing electromagnetic rail accelerators.
Using Graph and Vertex Entropy to Compare Empirical Graphs with Theoretical Graph Models
Tomasz Kajdanowicz
2016-09-01
Full Text Available Over the years, several theoretical graph generation models have been proposed. Among the most prominent are: the Erdős–Renyi random graph model, Watts–Strogatz small world model, Albert–Barabási preferential attachment model, Price citation model, and many more. Often, researchers working with real-world data are interested in understanding the generative phenomena underlying their empirical graphs. They want to know which of the theoretical graph generation models would most probably generate a particular empirical graph. In other words, they expect some similarity assessment between the empirical graph and graphs artificially created from theoretical graph generation models. Usually, in order to assess the similarity of two graphs, centrality measure distributions are compared. For a theoretical graph model this means comparing the empirical graph to a single realization of a theoretical graph model, where the realization is generated from the given model using an arbitrary set of parameters. The similarity between centrality measure distributions can be measured using standard statistical tests, e.g., the Kolmogorov–Smirnov test of distances between cumulative distributions. However, this approach is both error-prone and leads to incorrect conclusions, as we show in our experiments. Therefore, we propose a new method for graph comparison and type classification by comparing the entropies of centrality measure distributions (degree centrality, betweenness centrality, closeness centrality. We demonstrate that our approach can help assign the empirical graph to the most similar theoretical model using a simple unsupervised learning method.
Towards Increased Relevance: Context-Adapted Models of the Learning Organization
Örtenblad, Anders
2015-01-01
Purpose: The purposes of this paper are to take a closer look at the relevance of the idea of the learning organization for organizations in different generalized organizational contexts; to open up for the existence of multiple, context-adapted models of the learning organization; and to suggest a number of such models.…
Towards Increased Relevance: Context-Adapted Models of the Learning Organization
Örtenblad, Anders
2015-01-01
Purpose: The purposes of this paper are to take a closer look at the relevance of the idea of the learning organization for organizations in different generalized organizational contexts; to open up for the existence of multiple, context-adapted models of the learning organization; and to suggest a number of such models.…
Thomas E. Dilts; Peter J. Weisberg; Camie M. Dencker; Jeanne C. Chambers
2015-01-01
We have three goals. (1) To develop a suite of functionally relevant climate variables for modelling vegetation distribution on arid and semi-arid landscapes of the Great Basin, USA. (2) To compare the predictive power of vegetation distribution models based on mechanistically proximate factors (water deficit variables) and factors that are more mechanistically removed...
Control-relevant modeling and simulation of a SOFC-GT hybrid system
Rambabu Kandepu
2006-07-01
Full Text Available In this paper, control-relevant models of the most important components in a SOFC-GT hybrid system are described. Dynamic simulations are performed on the overall hybrid system. The model is used to develop a simple control structure, but the simulations show that more elaborate control is needed.
The transtheoretical model and substance dependence: theoretical and practical aspects
2009-01-01
OBJECTIVE: This paper aims to present and discuss the Transtheoretical Model and its importance for the treatment of substance abuse disorders. METHOD: A literature review was made based on articles from the last 10 years in substance use with human subjects found in PubMed (Medline) and the Scientific Electronic Library Online, as well as on the main books written by the creators of the model. From the initial collection of articles related to the Transtheoretical Model, the University of Rh...
Jones, Ant
2015-01-01
The construction of viable and physically-realistic interstellar dust models is only possible if the constraints imposed by laboratory data on interstellar dust analogue materials are respected and used within a meaningful theoretical framework. These physical dust models can then be directly compared to observations without the need for any tuning to fit the observations. Such models will generally fail to achieve the excellent fits to observations that empirical models are able to achieve. However, the physically-realistic approach will necessarily lead to a deeper insight and a fuller understanding of the nature and evolution of interstellar dust. The THEMIS modelling approach, based on (hydrogenated) amorphous carbons and amorphous silicates with metallic Fe and/or FeS nano-inclusions appears to be a promising move in this direction.
Theoretical modeling of sliding vane compressor with leakage
Al-Hawaj, Osama [Department of Mechanical Engineering, University of Kuwait, P.O. Box 5969, Safat 13060 (Kuwait)
2009-11-15
Performance of a sliding vane compressor is significantly influenced by the leakage effect occurring between adjacent cells during the compression phase of the cycle. In this paper, thermodynamic and dynamical mathematical models were formulated for a double action sliding vane compressor including leakage effect modeling. The leakage modeling is incorporated through an analytic pressure model with a single tunable parameter to be adjusted to correspond with specific compressor leakage characteristics. The effect of leakage on the cell pressure, temperature, mass, and work, and total vane torque variations were qualitatively investigated. The study illustrated the significant effect of leakage on power input requirement, discharge pressure and mass delivery, and less significant effect on mechanical efficiency and specific mass delivery. The validity of the simulation results is made by comparing the pressure work calculated from both the thermodynamic and the dynamic models. (author)
Munoz-Carpena, R.; Muller, S. J.; Chu, M.; Kiker, G. A.; Perz, S. G.
2014-12-01
Model Model complexity resulting from the need to integrate environmental system components cannot be understated. In particular, additional emphasis is urgently needed on rational approaches to guide decision making through uncertainties surrounding the integrated system across decision-relevant scales. However, in spite of the difficulties that the consideration of modeling uncertainty represent for the decision process, it should not be avoided or the value and science behind the models will be undermined. These two issues; i.e., the need for coupled models that can answer the pertinent questions and the need for models that do so with sufficient certainty, are the key indicators of a model's relevance. Model relevance is inextricably linked with model complexity. Although model complexity has advanced greatly in recent years there has been little work to rigorously characterize the threshold of relevance in integrated and complex models. Formally assessing the relevance of the model in the face of increasing complexity would be valuable because there is growing unease among developers and users of complex models about the cumulative effects of various sources of uncertainty on model outputs. In particular, this issue has prompted doubt over whether the considerable effort going into further elaborating complex models will in fact yield the expected payback. New approaches have been proposed recently to evaluate the uncertainty-complexity-relevance modeling trilemma (Muller, Muñoz-Carpena and Kiker, 2011) by incorporating state-of-the-art global sensitivity and uncertainty analysis (GSA/UA) in every step of the model development so as to quantify not only the uncertainty introduced by the addition of new environmental components, but the effect that these new components have over existing components (interactions, non-linear responses). Outputs from the analysis can also be used to quantify system resilience (stability, alternative states, thresholds or tipping
Experimental observations and theoretical models for beam-beam phenomena
Kheifets, S.
1981-03-01
The beam-beam interaction in storage rings exhibits all the characteristics of nonintegrable dynamical systems. Here one finds all kinds of resonances, closed orbits, stable and unstable fixed points, stochastic layers, chaotic behavior, diffusion, etc. The storage ring itself being an expensive device nevertheless while constructed and put into operation presents a good opportunity of experimentally studying the long-time behavior of both conservative (proton machines) and nonconservative (electron machines) dynamical systems - the number of bunch-bunch interactions routinely reaches values of 10/sup 10/-10/sup 11/ and could be increased by decreasing the beam current. At the same time the beam-beam interaction puts practical limits for the yield of the storage ring. This phenomenon not only determines the design value of main storage ring parameters (luminosity, space charge parameters, beam current), but also in fact prevents many of the existing storage rings from achieving design parameters. Hence, the problem has great practical importance along with its enormous theoretical interest. A brief overview of the problem is presented.
Rigorous theoretical derivation of lumped models to transmission line systems
Zhao Jixiang
2012-01-01
By virtue of the negative electric parameter concept,i.e.negative lumped resistance,inductance,conductance and capacitance (N-RLGC),the lumped equivalent models of transmission line systems,including the circuit model,two-port π-network and T-network,are given.We start from the N-segment-ladder-like equivalent networks composed distributed parameters,and achieve the input impedance in the form of a continued fraction.Utilizing the continued fraction theory,the expressions of input impedance are obtained under three kinds of extreme cases,i.e.the load impedances are equal to zero,infinity and characteristic impedance,respectively.When the number of segment N is limited to infinity,they are transformed to lumped elements.Comparison between the distributed model and lumped model of transmission lines,the expression of tanh yd,which is the key term in the transmission line equations,are obtained by RLGC,furthermore,according to input admittance,admittance matrix and ABCD matrix of transmission lines,the lumped equivalent circuit models,π-networks and T-networks have been given.The models are verified in the frequency and time domain,respectively,showing that the models are accurate and efficient.
Transdiagnostic models of anxiety disorder: Theoretical and empirical underpinnings.
Norton, Peter J; Paulus, Daniel J
2017-08-01
Despite the increasing development, evaluation, and adoption of transdiagnostic cognitive behavioral therapies, relatively little has been written to detail the conceptual and empirical psychopathology framework underlying transdiagnostic models of anxiety and related disorders. In this review, the diagnostic, genetic, neurobiological, developmental, behavioral, cognitive, and interventional data underlying the model are described, with an emphasis on highlighting elements that both support and contradict transdiagnostic conceptualizations. Finally, a transdiagnostic model of anxiety disorder is presented and key areas of future evaluation and refinement are discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.
Membrane Phospholipid Redistribution in Cytokinesis: A Theoretical Model
Mei-Wen AN; Wen-Zhou WU; Wei-Yi CHEN
2005-01-01
In cell mitosis, cytokinesis is a major deformation process, during which the site of the contractile ring is determined by the biochemical stimulus from asters of the mitotic apparatus, actin and myosin assembly is related to the motion of membrane phospholipids, and local distribution and arrangement of the microfilament cytoskeleton are different at different cytokinesis stages. Based on the Zinemanas-Nir model, a new model is proposed in this study to simulate the entire process by coupling the biochemical stimulus with the mechanical actions. There were three assumptions in this model: the movements of phospholipid proteins are driven by gradients of biochemical stimulus on the membrane surface; the local assembly of actin and myosin filament depends on the amount of phospholipid proteins at the same location;and the surface tension includes membrane tensions due to both the passive deformation of the membrane and the active contraction of actin filament, which is determined by microfilament redistribution and rearrangement. This model could explain the dynamic movement of microfilaments during cytokinesis and predict cell deformation. The calculated results from this model demonstrated that the reorientation of phospholipid proteins and the redistribution and reorientation of microfilaments may play a crucial role in cell division. This model may better represent the cytokinesis process by the introduction of biochemical stimulus.
Theoretic models for recommendation and implementation of assistive technology
Ana Cristina de Jesus Alves
2016-07-01
Full Text Available Introduction: The latest international researches seek to understand the factors affecting the successful use of assistive technology devices through studies regarding the assessments systematizing; abandonment of devices; or theoric models that consider the aspects of those devices implementation. In Brazil the researches are focused on developing new technologies and there are still not sufficient studies related to the successful use of devices and ways of assistive technology implementation. Objective: To identify conceptual models used for indication and implementation of assistive technology devices. Method: Literature review. The survey was conducted in six databases: CINAHAL, Eric, GALE, LILACS, MEDLINE e PsycInfo. A critical analysis described by Grant and Booth was used. Results: There are no records of a Brazilian survey and among 29 selected articles, 17 conceptual models used in the area of AT were found; of these, 14 were specific to AT. The results showed that the new conceptual models of TA are under development and the conceptual model “Matching Person and Technology – MPT” was the most mentioned. Conclusion: We can observe that the practices related to TA area in international context shows a correlation with conceptual models, thus, we hope this study might have the capacity to contribute for the propagation of this precepts at national level
Design theoretic analysis of three system modeling frameworks.
McDonald, Michael James
2007-05-01
This paper analyzes three simulation architectures from the context of modeling scalability to address System of System (SoS) and Complex System problems. The paper first provides an overview of the SoS problem domain and reviews past work in analyzing model and general system complexity issues. It then identifies and explores the issues of vertical and horizontal integration as well as coupling and hierarchical decomposition as the system characteristics and metrics against which the tools are evaluated. In addition, it applies Nam Suh's Axiomatic Design theory as a construct for understanding coupling and its relationship to system feasibility. Next it describes the application of MATLAB, Swarm, and Umbra (three modeling and simulation approaches) to modeling swarms of Unmanned Flying Vehicle (UAV) agents in relation to the chosen characteristics and metrics. Finally, it draws general conclusions for analyzing model architectures that go beyond those analyzed. In particular, it identifies decomposition along phenomena of interaction and modular system composition as enabling features for modeling large heterogeneous complex systems.
Overview of Threats and Failure Models for Safety-Relevant Computer-Based Systems
Torres-Pomales, Wilfredo
2015-01-01
This document presents a high-level overview of the threats to safety-relevant computer-based systems, including (1) a description of the introduction and activation of physical and logical faults; (2) the propagation of their effects; and (3) function-level and component-level error and failure mode models. These models can be used in the definition of fault hypotheses (i.e., assumptions) for threat-risk mitigation strategies. This document is a contribution to a guide currently under development that is intended to provide a general technical foundation for designers and evaluators of safety-relevant systems.
A theoretical model for the associative nature of conference participation
Smiljanić, Jelena; Kauppinen, Tomi; Dankulov, Marija Mitrović
2015-01-01
Participation in conferences is an important part of every scientific career. Conferences provide an opportunity for a fast dissemination of latest results, discussion and exchange of ideas, and broadening of scientists' collaboration network. The decision to participate in a conference depends on several factors like the location, cost, popularity of keynote speakers, and the scientists' association with the community. Here we discuss and formulate the problem of discovering how a scientists' previous participation affects her/his future participations in the same conference series. We develop a stochastic model to examine scientists' participation patterns in conferences and compare our model with data from six conferences across various scientific fields and communities. Our model shows that the probability for a scientist to participate in a given conference series strongly depends on the balance between the number of participations and non-participations during his/her early connections with the communit...
Theoretical model for ultracold molecule formation via adaptive feedback control
Poschinger, U; Wester, R; Weidemüller, M; Koch, C P; Kosloff, R; Poschinger, Ulrich; Salzmann, Wenzel; Wester, Roland; Weidemueller, Matthias; Koch, Christiane P.; Kosloff, Ronnie
2006-01-01
We investigate pump-dump photoassociation of ultracold molecules with amplitude- and phase-modulated femtosecond laser pulses. For this purpose a perturbative model for the light-matter interaction is developed and combined with a genetic algorithm for adaptive feedback control of the laser pulse shapes. The model is applied to the formation of 85Rb2 molecules in a magneto-optical trap. We find for optimized pulse shapes an improvement for the formation of ground state molecules by more than a factor of 10 compared to unshaped pulses at the same pump-dump delay time, and by 40% compared to unshaped pulses at the respective optimal pump-dump delay time. Since our model yields directly the spectral amplitudes and phases of the optimized pulses, the results are directly applicable in pulse shaping experiments.
A control theoretic model of driver steering behavior
Donges, E.
1977-01-01
A quantitative description of driver steering behavior such as a mathematical model is presented. The steering task is divided into two levels: (1) the guidance level involving the perception of the instantaneous and future course of the forcing function provided by the forward view of the road, and the response to it in an anticipatory open-loop control mode; (2) the stabilization level whereby any occuring deviations from the forcing function are compensated for in a closed-loop control mode. This concept of the duality of the driver's steering activity led to a newly developed two-level model of driver steering behavior. Its parameters are identified on the basis of data measured in driving simulator experiments. The parameter estimates of both levels of the model show significant dependence on the experimental situation which can be characterized by variables such as vehicle speed and desired path curvature.
Gonzálvez, Alicia G; González Ureña, Ángel
2012-10-01
A laser spectroscopic technique is described that combines transmission and resonance-enhanced Raman inelastic scattering together with low laser power (view, a model for the Raman signal dependence on the sample thickness is also presented. Essentially, the model considers the sample to be homogeneous and describes the underlying physics using only three parameters: the Raman cross-section, the laser-radiation attenuation cross-section, and the Raman signal attenuation cross-section. The model was applied successfully to describe the sample-size dependence of the Raman signal in both β-carotene standards and carrot roots. The present technique could be useful for direct, fast, and nondestructive investigations in food quality control and analytical or physiological studies of animal and human tissues.
Turbulent convection model in the overshooting region: II. Theoretical analysis
Zhang, S Q
2012-01-01
Turbulent convection models are thought to be good tools to deal with the convective overshooting in the stellar interior. However, they are too complex to be applied in calculations of stellar structure and evolution. In order to understand the physical processes of the convective overshooting and to simplify the application of turbulent convection models, a semi-analytic solution is necessary. We obtain the approximate solution and asymptotic solution of the turbulent convection model in the overshooting region, and find some important properties of the convective overshooting: I. The overshooting region can be partitioned into three parts: a thin region just outside the convective boundary with high efficiency of turbulent heat transfer, a power law dissipation region of turbulent kinetic energy in the middle, and a thermal dissipation area with rapidly decreasing turbulent kinetic energy. The decaying indices of the turbulent correlations $k$, $\\bar{u_{r}'T'}$, and $\\bar{T'T'}$ are only determined by the ...
Verifying a theoretical model of loads on an asymmetric disk
Krauze, K.
1985-02-01
The results are evaluated of testing a single asymmetric disk cutter used for coal cutting under operational conditions in an underground mine. The tests were aimed at verifying a mathematical model of coal cutting. The mean conventional pressure, a term used by the author, was determined. Forces acting on an asymmetric cutting disk calculated by mathematical modeling were compared to those determined in the tests. Comparisons showed that the model accurately describes coal cutting: in the case of tangential force error was not higher than 18%, in the case of lateral force it was not higher than 46% and in the case of compression force it was not higher than 15%. The method for calculating loads on an asymmetric disk cutter was characterized by reduced labor consumption and low number of tests. 1 reference.
Impression Formation and Modifiability: Testing a Theoretical Model
Mrug, Sylvie; Hoza, Betsy
2007-01-01
This study proposed and tested a developmental model of impression formation based on observed behavior, prior expectancies, and additional incongruent information. Participants were 51 kindergartners, 53 second graders, and 104 college students who provided trait and liking judgments after watching a child actor engage in behaviors from three…
Voronoi Cell Patterns: theoretical model and application to submonolayer growth
González, Diego Luis; Einstein, T. L.
2012-02-01
We use a simple fragmentation model to describe the statistical behavior of the Voronoi cell patterns generated by a homogeneous and isotropic set of points in 1D and in 2D. In particular, we are interested in the distribution of sizes of these Voronoi cells. Our model is completely defined by two probability distributions in 1D and again in 2D, the probability to add a new point inside an existing cell and the probability that this new point is at a particular position relative to the preexisting point inside this cell. In 1D the first distribution depends on a single parameter while the second distribution is defined through a fragmentation kernel; in 2D both distributions depend on a single parameter. The fragmentation kernel and the control parameters are closely related to the physical properties of the specific system under study. We apply our model to describe the Voronoi cell patterns of island nucleation for critical island sizes i=0,1,2,3. Experimental results for the Voronoi cells of InAs/GaAs quantum dots are also described by our model.
Photoabsorption spectrum of helium trimer cation—Theoretical modeling
Kalus, René [Centre of Excellence IT4Innovations and Department of Applied Mathematics, VSB-Technical University of Ostrava, 17. listopadu 15, 708 33 Ostrava (Czech Republic); Karlický, František [Regional Centre of Advanced Technologies and Materials and Department of Physical Chemistry, Faculty of Science, Palacký University, Tř. 17. listopadu 12, 771 46 Olomouc (Czech Republic); Lepetit, Bruno [Laboratoire Collisions Agrégats Réactivité, IRSAMC and UMR5589 du CNRS, Université de Toulouse, UPS, 118 route de Narbonne, 31062 Toulouse Cedex (France); Paidarová, Ivana [J. Heyrovský Institute of Physical Chemistry, ASCR, v.v.i., Dolejškova 3, 182 23 Praha (Czech Republic); Gadea, Florent Xavier [Laboratoire de Chimie et de Physique Quantiques, IRSAMC and UMR5626 du CNRS, Université de Toulouse, UPS, 118 route de Narbonne, 31062 Toulouse Cedex (France)
2013-11-28
The photoabsorption spectrum of He{sub 3}{sup +} is calculated for two semiempirical models of intracluster interactions and compared with available experimental data reported in the middle UV range [H. Haberland and B. von Issendorff, J. Chem. Phys. 102, 8773 (1995)]. Nuclear delocalization effects are investigated via several approaches comprising quantum samplings using either exact or approximate (harmonic) nuclear wavefunctions, as well as classical samplings based on the Monte Carlo methodology. Good agreement with the experiment is achieved for the model by Knowles et al., [Mol. Phys. 85, 243 (1995); Mol. Phys. 87, 827 (1996)] whereas the model by Calvo et al., [J. Chem. Phys. 135, 124308 (2011)] exhibits non-negligible deviations from the experiment. Predictions of far UV absorption spectrum of He{sub 3}{sup +}, for which no experimental data are presently available, are reported for both models and compared to each other as well as to the photoabsorption spectrum of He{sub 2}{sup +}. A simple semiempirical point-charge approximation for calculating transition probabilities is shown to perform well for He{sub 3}{sup +}.
Model United Nations and Deep Learning: Theoretical and Professional Learning
Engel, Susan; Pallas, Josh; Lambert, Sarah
2017-01-01
This article demonstrates that the purposeful subject design, incorporating a Model United Nations (MUN), facilitated deep learning and professional skills attainment in the field of International Relations. Deep learning was promoted in subject design by linking learning objectives to Anderson and Krathwohl's (2001) four levels of knowledge or…
Theoretical biology: Comparing models of species abundance - Brief Communications Arising
Chave, J.; Alonso, D.; Etienne, R.S.
2006-01-01
Ecologists are struggling to explain how so many tropical tree species can coexist in tropical forests, and several empirical studies have demonstrated that negative density dependence is an important mechanism of tree-species coexistence1, 2. Volkov et al.3 compare a model incorporating negative de
Theoretical Modeling of Mechanical Behavior and Release Properties of Microcapsules
Sagis, L.M.C.
2015-01-01
Microcapsules in food often have a shell with a complex microstructure; the mechanical and structural properties of these shells affect the response of the capsules to deforming forces and the release kinetics of encapsulated components. In this chapter we will discuss a number of models which are t
Accelerator simulation and theoretical modelling of radiation effects (SMoRE)
2018-01-01
This publication summarizes the findings and conclusions of the IAEA coordinated research project (CRP) on accelerator simulation and theoretical modelling of radiation effects, aimed at supporting Member States in the development of advanced radiation-resistant structural materials for implementation in innovative nuclear systems. This aim can be achieved through enhancement of both experimental neutron-emulation capabilities of ion accelerators and improvement of the predictive efficiency of theoretical models and computer codes. This dual approach is challenging but necessary, because outputs of accelerator simulation experiments need adequate theoretical interpretation, and theoretical models and codes need high dose experimental data for their verification. Both ion irradiation investigations and computer modelling have been the specific subjects of the CRP, and the results of these studies are presented in this publication which also includes state-ofthe- art reviews of four major aspects of the project...
Motility of a model bristle-bot: A theoretical analysis
Cicconofri, Giancarlo; DeSimone, Antonio
2015-11-01
Bristle-bots are legged robots that can be easily made out of a toothbrush head and a small vibrating engine. Despite their simple appearance, the mechanism enabling them to propel themselves by exploiting friction with the substrate is far from trivial. Numerical experiments on a model bristle-bot have been able to reproduce such a mechanism revealing, in addition, the ability to switch direction of motion by varying the vibration frequency. This paper provides a detailed account of these phenomena through a fully analytical treatment of the model. The equations of motion are solved through an expansion in terms of a properly chosen small parameter. The convergence of the expansion is rigorously proven. In addition, the analysis delivers formulas for the average velocity of the robot and for the frequency at which the direction switch takes place. A quantitative description of the mechanism for the friction modulation underlying the motility of the bristle-bot is also provided.
Model-theoretical foundation of action and progression
田启家; 史忠植
1997-01-01
Action is one of the most important concepts in computer science, and situation calculus is the standard formalism for representing and reasoning about actions and their effects. Situation calculus essentially could be presented in a logic framework. Based on the framework LR, such a logic framework is given. Minimal action theory is proposed and studied from the point of view of model theory. By theorems of mathematical logic, some results about the definability about the progression in minimal action theory are obtained.
Hybrid empirical--theoretical approach to modeling uranium adsorption
Hull, Larry C.; Grossman, Christopher; Fjeld, Robert A.; Coates, John T.; Elzerman, Alan W
2004-05-01
An estimated 330 metric tons of U are buried in the radioactive waste Subsurface Disposal Area (SDA) at the Idaho National Engineering and Environmental Laboratory (INEEL). An assessment of U transport parameters is being performed to decrease the uncertainty in risk and dose predictions derived from computer simulations of U fate and transport to the underlying Snake River Plain Aquifer. Uranium adsorption isotherms were measured for 14 sediment samples collected from sedimentary interbeds underlying the SDA. The adsorption data were fit with a Freundlich isotherm. The Freundlich n parameter is statistically identical for all 14 sediment samples and the Freundlich K{sub f} parameter is correlated to sediment surface area (r{sup 2}=0.80). These findings suggest an efficient approach to material characterization and implementation of a spatially variable reactive transport model that requires only the measurement of sediment surface area. To expand the potential applicability of the measured isotherms, a model is derived from the empirical observations by incorporating concepts from surface complexation theory to account for the effects of solution chemistry. The resulting model is then used to predict the range of adsorption conditions to be expected in the vadose zone at the SDA based on the range in measured pore water chemistry. Adsorption in the deep vadose zone is predicted to be stronger than in near-surface sediments because the total dissolved carbonate decreases with depth.
A Theoretical Model for the Associative Nature of Conference Participation.
Jelena Smiljanić
Full Text Available Participation in conferences is an important part of every scientific career. Conferences provide an opportunity for a fast dissemination of latest results, discussion and exchange of ideas, and broadening of scientists' collaboration network. The decision to participate in a conference depends on several factors like the location, cost, popularity of keynote speakers, and the scientist's association with the community. Here we discuss and formulate the problem of discovering how a scientist's previous participation affects her/his future participations in the same conference series. We develop a stochastic model to examine scientists' participation patterns in conferences and compare our model with data from six conferences across various scientific fields and communities. Our model shows that the probability for a scientist to participate in a given conference series strongly depends on the balance between the number of participations and non-participations during his/her early connections with the community. An active participation in a conference series strengthens the scientist's association with that particular conference community and thus increases the probability of future participations.
A THEORETICAL MODEL OF SOCIO-PSYCHOLOGICAL SUPPORT WORK PROCESSES FOR MANAGEMENT OF PRODUCTION TEAM
Tatyana Gennadevna Pronyushkina
2015-01-01
This article discusses the management of production team, in particular the developed theoretical model of socio-psychological support work processes for management of production team. The author of the research are formulated the purpose and objectives of social-psychological work on management of the production team. Developed in the study a theoretical model aimed at determining the conditions and the identification of features of effective management of the enterprise taking into account ...
The LAILAPS search engine: a feature model for relevance ranking in life science databases.
Lange, Matthias; Spies, Karl; Colmsee, Christian; Flemming, Steffen; Klapperstück, Matthias; Scholz, Uwe
2010-03-25
Efficient and effective information retrieval in life sciences is one of the most pressing challenge in bioinformatics. The incredible growth of life science databases to a vast network of interconnected information systems is to the same extent a big challenge and a great chance for life science research. The knowledge found in the Web, in particular in life-science databases, are a valuable major resource. In order to bring it to the scientist desktop, it is essential to have well performing search engines. Thereby, not the response time nor the number of results is important. The most crucial factor for millions of query results is the relevance ranking. In this paper, we present a feature model for relevance ranking in life science databases and its implementation in the LAILAPS search engine. Motivated by the observation of user behavior during their inspection of search engine result, we condensed a set of 9 relevance discriminating features. These features are intuitively used by scientists, who briefly screen database entries for potential relevance. The features are both sufficient to estimate the potential relevance, and efficiently quantifiable. The derivation of a relevance prediction function that computes the relevance from this features constitutes a regression problem. To solve this problem, we used artificial neural networks that have been trained with a reference set of relevant database entries for 19 protein queries. Supporting a flexible text index and a simple data import format, this concepts are implemented in the LAILAPS search engine. It can easily be used both as search engine for comprehensive integrated life science databases and for small in-house project databases. LAILAPS is publicly available for SWISSPROT data at http://lailaps.ipk-gatersleben.de.
Radhakrishnan, Mala L; Tidor, Bruce
2008-05-01
Drug resistance is a significant obstacle in the effective treatment of diseases with rapidly mutating targets, such as AIDS, malaria, and certain forms of cancer. Such targets are remarkably efficient at exploring the space of functional mutants and at evolving to evade drug binding while still maintaining their biological role. To overcome this challenge, drug regimens must be active against potential target variants. Such a goal may be accomplished by one drug molecule that recognizes multiple variants or by a drug "cocktail"--a small collection of drug molecules that collectively binds all desired variants. Ideally, one wants the smallest cocktail possible due to the potential for increased toxicity with each additional drug. Therefore, the task of designing a regimen for multiple target variants can be framed as an optimization problem--find the smallest collection of molecules that together "covers" the relevant target variants. In this work, we formulate and apply this optimization framework to theoretical model target ensembles. These results are analyzed to develop an understanding of how the physical properties of a target ensemble relate to the properties of the optimal cocktail. We focus on electrostatic variation within target ensembles, as it is one important mechanism by which drug resistance is achieved. Using integer programming, we systematically designed optimal cocktails to cover model target ensembles. We found that certain drug molecules covered much larger regions of target space than others, a phenomenon explained by theory grounded in continuum electrostatics. Molecules within optimal cocktails were often dissimilar, such that each drug was responsible for binding variants with a certain electrostatic property in common. On average, the number of molecules in the optimal cocktails correlated with the number of variants, the differences in the variants' electrostatic properties at the binding interface, and the level of binding affinity
GSTARS computer models and their applications, part I: theoretical development
无
2008-01-01
GSTARS is a series of computer models developed by the U.S. Bureau of Reclamation for alluvial river and reservoir sedimentation studies while the authors were employed by that agency. The first version of GSTARS was released in 1986 using Fortran IV for mainframe computers. GSTARS 2.0 was released in 1998 for personal computer application with most of the code in the original GSTARS revised, improved, and expanded using Fortran IV/77. GSTARS 2.1 is an improved and revised GSTARS 2.0 with graphical user interface. The unique features of all GSTARS models are the conjunctive use of the stream tube concept and of the minimum stream power theory. The application of minimum stream power theory allows the determination of optimum channel geometry with variable channel width and cross-sectional shape. The use of the stream tube concept enables the simulation of river hydraulics using one-dimensional numerical solutions to obtain a semi-two-dimensional presentation of the hydraulic conditions along and across an alluvial channel. According to the stream tube concept, no water or sediment particles can cross the walls of stream tubes, which is valid for many natural rivers. At and near sharp bends, however, sediment particles may cross the boundaries of stream tubes. GSTARS3, based on FORTRAN 90/95, addresses this phenomenon and further expands the capabilities of GSTARS 2.1 for cohesive and non-cohesive sediment transport in rivers and reservoirs. This paper presents the concepts, methods, and techniques used to develop the GSTARS series of computer models, especially GSTARS3.
Graph theoretical analysis of the energy landscape of model polymers.
Baiesi, Marco; Bongini, Lorenzo; Casetti, Lapo; Tattini, Lorenzo
2009-07-01
In systems characterized by a rough potential-energy landscape, local energetic minima and saddles define a network of metastable states whose topology strongly influences the dynamics. Changes in temperature, causing the merging and splitting of metastable states, have nontrivial effects on such networks and must be taken into account. We do this by means of a recently proposed renormalization procedure. This method is applied to analyze the topology of the network of metastable states for different polypeptidic sequences in a minimalistic polymer model. A smaller spectral dimension emerges as a hallmark of stability of the global energy minimum and highlights a nonobvious link between dynamic and thermodynamic properties.
Wiesen, S.; Fundamenski, W.; Wischmeier, M.
2011-01-01
A revised formulation of the perpendicular diffusive transport model in 2D multi-fluid edge codes is proposed. Based on theoretical predictions and experimental observations a dependence on collisionality is introduced into the transport model of EDGE2D–EIRENE. The impact on time-dependent JET ga...
Preterm piglets are a clinically relevant model of pediatric GI disease
The goal of our research is to establish how nutritional support, enteral versus parenteral, affects gut function and susceptibility to disease in early development. We and others have used the neonatal pig to establish unique models of clinically relevant problems in pediatric gastroenterology, esp...
YANG Jing
2014-01-01
Taken discourse production as the research objective, it holds that discourse production is dynamic in human communi-cation. It attempts to analyze the dynamics on the basis of Relevance-adaption model from the perspective of cognitive pragmat-ics and explain the role of the context dynamics that plays in the discourse production.
A theoretical design for learning model addressing the networked society
Levinsen, Karin; Nielsen, Janni; Sørensen, Birgitte Holm
2010-01-01
is continuously decreasing. We teach for deep learning but are confronted by students' cost-benefit strategies when they navigate through the study programme under time pressure. To meet these challenges a Design for Learning Model has been developed. The aim is to provide a scaffold that ensures students......The transition from the industrial to the networked society produces contradictions that challenges the educational system and force it to adapt to new conditions. In a Danish virtual Master in Information and Communication Technologies and Learning (MIL) these contradictions appear as a field...... of tension between time resources and the demand for educational quality. Our approach is based on constructivist and social constructivist traditions but we are required to measure students according to a list of learning goals. The size of curriculum is growing while the time available for learning...
Theoretical models for polarimetric microwave remote sensing of earth terrain
Borgeaud, M.; Nghiem, S. V.; Shin, R. T.; Kong, J. A.
1989-01-01
Using the two-layer anisotropic random medium, a mathematically rigorous, fully polarimetric model is developed to compute the Mueller and covariance matrices in the backscattering direction for various kinds of earth terrain. The electric field is first written in the form of an integral equation involving the unperturbed dyadic Green's function in the absence of the permittivity fluctuations. The integral equation is then solved by an iterative series known as the Born series. With only the first term of the series, which physically describes a single scattering process, the fully polarimetric backscattering coefficients are derived. Four different kinds of upgoing and downgoing waves exist due to the excitation of both ordinary and extraordinary waves in the anisotropic random medium. An averaging scheme over the azimuthal direction is used to simulate the effects on the radar backscattering due to the azimuthal randomness in the growth direction of leaves in tree and grass fields.
Theoretical model for assessing properties of local structures in metalloprotein
Koyimatu, M.; Shimahara, H.; Iwayama, M.; Sugimori, K.; Kawaguchi, K.; Saito, H.; Nagao, H.
2013-02-01
For model structures containing two aromatic rings such as the indole of Trp5 and the imidazole of His64 in human carbonic anhydrase (hCAII), the location and orientation of the rings with regard to each other contribute to the magnitude of the entire interaction energy. Here the energetic contribution of the indole ring of Trp5 on the imidazole ring of the "out" conformation of His64 were calculated to compare with that of the alternative "in" conformation of His64 by using the MP2/6-311++G(d,p)//B3LYP/6-31G(d,p) method. We suggest that 1) Trp5 and the "out" conformation of His64 are predicted to form a stack of planar parallel rings via π-stacking interaction and 2) the energy is 1.73-1.83 kcal/mol to stabilize the "out" conformation, compared with the "in" conformation.
Theoretical models for fluid thermodynamics based on the quasi-Gaussian entropy theory
Amadei, Andrea
1998-01-01
Summary The theoretical modeling of fluid thermodynamics is one of the most challenging fields in physical chemistry. In fact the fluid behavior, except at very low density conditions, is still extremely difficult to be modeled from a statistical mechanical point of view, as for any realistic model
Lise, W.; Linderhof, V.G.M.; Kuik, O.; Kemfert, C.; Ostling, R.; Heinzow, T.
2006-01-01
This paper develops a static computational game theoretic model. Illustrative results for the liberalising European electricity market are given to demonstrate the type of economic and environmental results that can be generated with the model. The model is empirically calibrated to eight
Lise, W.; Linderhof, V.G.M.; Kuik, O.; Kemfert, C.; Ostling, R.; Heinzow, T.
2006-01-01
This paper develops a static computational game theoretic model. Illustrative results for the liberalising European electricity market are given to demonstrate the type of economic and environmental results that can be generated with the model. The model is empirically calibrated to eight Northweste
THEORETICAL FLOW MODEL THROUGH A CENTRIFUGAL PUMP USED FOR WATER SUPPLY IN AGRICULTURE IRRIGATION
SCHEAUA Fanel Dorel
2017-05-01
motion of the rotor. A theoretical model for calculating the flow of the working fluid through the interior of a centrifugal pump model is presented in this paper as well as the numerical analysis on the virtual model performed with the ANSYS CFX software in order to highlight the flow parameters and flow path-lines that are formed during centrifugal pump operation.
Theoretical model of the helium zone plate microscope
Salvador Palau, Adrià; Bracco, Gianangelo; Holst, Bodil
2017-01-01
Neutral helium microscopy is a new technique currently under development. Its advantages are the low energy, charge neutrality, and inertness of the helium atoms, a potential large depth of field, and the fact that at thermal energies the helium atoms do not penetrate into any solid material. This opens the possibility, among others, for the creation of an instrument that can measure surface topology on the nanoscale, even on surfaces with high aspect ratios. One of the most promising designs for helium microscopy is the zone plate microscope. It consists of a supersonic expansion helium beam collimated by an aperture (skimmer) focused by a Fresnel zone plate onto a sample. The resolution is determined by the focal spot size, which depends on the size of the skimmer, the optics of the system, and the velocity spread of the beam through the chromatic aberrations of the zone plate. An important factor for the optics of the zone plate is the width of the outermost zone, corresponding to the smallest opening in the zone plate. The width of the outermost zone is fabrication limited to around 10 nm with present-day state-of-the-art technology. Due to the high ionization potential of neutral helium atoms, it is difficult to build efficient helium detectors. Therefore, it is crucial to optimize the microscope design to maximize the intensity for a given resolution and width of the outermost zone. Here we present an optimization model for the helium zone plate microscope. Assuming constant resolution and width of the outermost zone, we are able to reduce the problem to a two-variable problem (zone plate radius and object distance) and we show that for a given beam temperature and pressure, there is always a single intensity maximum. We compare our model with the highest-resolution zone plate focusing images published and show that the intensity can be increased seven times. Reducing the width of the outermost zone to 10 nm leads to an increase in intensity of more than 8000
T3 and cardiac myocyte cell: a theoretical model.
Athanasios, Tsatsaris; Antonios, Baldoukas; Antonios, Loumousiotis; Eustathios, Koukounaris; Maria, Giota; Despina, Perrea
2013-08-01
In the last decades, the outstanding role of Thyroid gland in regulating both physiological and pathological operation of cardiovascular system has been acknowledged worldwide. Three main domains of Thyroid function, that is to say, euthyroidism -hyperthyroidism-hypothyroidism, have a direct impact on cardiac response through a variety of mechanisms. Cellular pathways mediate in cardiac contractility, cardiac output, cardiac rhythm, arterial blood pressure and peripheral vessel resistance. Particular biochemical algorithms exist not only between Thyroid hormones' serum concentration and thyroid gland but also between the hormones' serum level and heart muscle genes. These biochemical pathways primarily regulate the appropriate secretion of levothyroxine (T4) and triiodothyronine(T3) via Thyroid- Stimulating-Hormone(TSH) pituitary system, and secondly adjust the cardiac function. In this study, a mathematic model has been developed describing significant aspects of positive or negative feedback mechanisms of THYRO-CARDIAC (THY-CAR) system along with potential applications of novel up-to-date patents in this area of research.
A beginner's guide to writing the nursing conceptual model-based theoretical rationale.
Gigliotti, Eileen; Manister, Nancy N
2012-10-01
Writing the theoretical rationale for a study can be a daunting prospect for novice researchers. Nursing's conceptual models provide excellent frameworks for placement of study variables, but moving from the very abstract concepts of the nursing model to the less abstract concepts of the study variables is difficult. Similar to the five-paragraph essay used by writing teachers to assist beginning writers to construct a logical thesis, the authors of this column present guidelines that beginners can follow to construct their theoretical rationale. This guide can be used with any nursing conceptual model but Neuman's model was chosen here as the exemplar.
Ogawa, Yutaro; Yamaguchi, Ikuhiro; Kotani, Kiyoshi; Jimbo, Yasuhiko
2017-02-24
Cognitive functions such as sensory processing and memory processes lead to phase synchronization in the electroencephalogram or local field potential between different brain regions. There are a lot of computational researches deriving phase locking values (PLVs), which are an index of phase synchronization intensity, from neural models. However, these researches derive PLVs numerically. To the best of our knowledge, there have been no reports on the derivation of a theoretical PLV. In this study, we propose an analytical method for deriving theoretical PLVs from a cortico-thalamic neural mass model described by a delay differential equation. First, the model for generating neural signals is transformed into a normal form of the Hopf bifurcation using center manifold reduction. Second, the normal form is transformed into a phase model that is suitable for analyzing synchronization phenomena. Third, the Fokker-Planck equation of the phase model is derived and the phase difference distribution is obtained. Finally, the PLVs are calculated from the stationary distribution of the phase difference. The validity of the proposed method is confirmed via numerical simulations. Furthermore, we apply the proposed method to a working memory process, and discuss the neurophysiological basis behind the phase synchronization phenomenon. The results demonstrate the importance of decreasing the intensity of independent noise during the working memory process. The proposed method will be of great use in various experimental studies and simulations relevant to phase synchronization, because it enables the effect of neurophysiological changes on PLVs to be analyzed from a mathematical perspective.
Theoretical mean-variance relationship of IP network traffic based on ON/OFF model
JIN Yi; ZHOU Gang; JIANG DongChen; YUAN Shuai; WANG LiLi; CAO JianTing
2009-01-01
Mean-variance relationship (MVR), nowadays agreed in power law form, is an important function. It Is currently used by traffic matrix estimation as a basic statistical assumption. Because all the existing papers obtain MVR only through empirical ways, they cannot provide theoretical support to power law MVR or the definition of its power exponent. Furthermore, because of the lack of theoretical model, all traffic matrix estimation methods based on MVR have not been theoretically supported yet. By observ-ing both our laboratory and campus network for more than one year, we find that such an empirical MVR is not sufficient to describe actual network traffic. In this paper, we derive a theoretical MVR from ON/OFF model. Then we prove that current empirical power law MVR is generally reasonable by the fact that it is an approximate form of theoretical MVR under specific precondition, which can theoretically support those traffic matrix estimation algorithms of using MVR. Through verifying our MVR by actual observation and public DECPKT traces, we verify that our theoretical MVR Is valid and more capable of describing actual network traffic than power law MVR.
A retroductive theoretical model of the pathway to chemical dependency in nurses.
Burns, C M
1998-02-01
Much of the research on chemical dependency in nurses over the past 25 years has been a-theoretical and has tended to focus on descriptive characteristics of nurses. This field of study lacks systematic knowledge building and a useful theoretical base. This article focuses on the development of a middle range theory that begins to explicate the transactions of the chemically dependent nurse with the environment and the process through which nurses become addicted. Steiner's theory models approach using retroductive inference was the method selected to develop the theory. Theoretical work from Bandura, Jessor, and Pender were used as source theories to develop the middle range theory presented.
Animal models of Parkinson's disease: limits and relevance to neuroprotection studies.
Bezard, Erwan; Yue, Zhenyu; Kirik, Deniz; Spillantini, Maria Grazia
2013-01-01
Over the last two decades, significant strides has been made toward acquiring a better knowledge of both the etiology and pathogenesis of Parkinson's disease (PD). Experimental models are of paramount importance to obtain greater insights into the pathogenesis of the disease. Thus far, neurotoxin-based animal models have been the most popular tools employed to produce selective neuronal death in both in vitro and in vivo systems. These models have been commonly referred to as the pathogenic models. The current trend in modeling PD revolves around what can be called the disease gene-based models or etiologic models. The value of utilizing multiple models with a different mechanism of insult rests on the premise that dopamine-producing neurons die by stereotyped cascades that can be activated by a range of insults, from neurotoxins to downregulation and overexpression of disease-related genes. In this position article, we present the relevance of both pathogenic and etiologic models as well as the concept of clinically relevant designs that, we argue, should be utilized in the preclinical development phase of new neuroprotective therapies before embarking into clinical trials.
Bugaev, Edgar; Petkov, Valery
2007-01-01
Possibilities of an experimental search for gamma-ray bursts from primordial black hole (PBH) evaporations in space are reconsidered. It is argued that the corresponding constraints which can be obtained in experiments with cosmic ray detectors strongly depend on theoretical approach used for a description of the PBH evaporation process. Predictions of several theoretical models for gamma-ray spectra from final stages of PBH life (integrated over time) are given.
The relevance of non-human primate and rodent malaria models for humans
Riley Eleanor
2011-02-01
Full Text Available Abstract At the 2010 Keystone Symposium on "Malaria: new approaches to understanding Host-Parasite interactions", an extra scientific session to discuss animal models in malaria research was convened at the request of participants. This was prompted by the concern of investigators that skepticism in the malaria community about the use and relevance of animal models, particularly rodent models of severe malaria, has impacted on funding decisions and publication of research using animal models. Several speakers took the opportunity to demonstrate the similarities between findings in rodent models and human severe disease, as well as points of difference. The variety of malaria presentations in the different experimental models parallels the wide diversity of human malaria disease and, therefore, might be viewed as a strength. Many of the key features of human malaria can be replicated in a variety of nonhuman primate models, which are very under-utilized. The importance of animal models in the discovery of new anti-malarial drugs was emphasized. The major conclusions of the session were that experimental and human studies should be more closely linked so that they inform each other, and that there should be wider access to relevant clinical material.
Open forward and inverse problems in theoretical modeling of bone tissue adaptation.
Zadpoor, Amir Abbas
2013-11-01
Theoretical modeling of bone tissue adaptation started several decades ago. Many important problems have been addressed in this area of research during the last decades. However, many important questions remain unanswered. In this paper, an overview of open problems in theoretical modeling of bone tissue adaptation is presented. First, the principal elements of bone tissue adaptation models are defined and briefly reviewed. Based on these principal elements, four categories of open problems are identified. Two of these categories primarily include forward problems, while two others include inverse problems. In every one of the identified categories, important open problems are highlighted and their importance is discussed. It is shown that most of previous studies on the theoretical modeling of bone tissue adaptation have been focused on the problems of the first category and not much is done in three other categories. The paper tries to highlight these potentially important problems that have been so far largely overlooked and to inspire new avenues of research.
Theoretical modeling on the laser induced effect of liquid crystal optical phased beam steering
He, Xiaoxian; Wang, Xiangru; Wu, Liang; Tan, Qinggui; Li, Man; Shang, Jiyang; Wu, Shuanghong; Huang, Ziqiang
2017-01-01
Non-mechanical laser beam steering has been reported previously in liquid crystal array devices. To be one of the most promising candidates to be practical non-mechanical laser deflector, its laser induced effect still has few theoretical model. In this paper, we propose a theoretical model to analyze this laser induced effect of LC-OPA to evaluate the deterioration on phased beam steering. The model has three parts: laser induced thermal distribution; temperature dependence of material parameters and beam steering deterioration. After these three steps, the far field of laser beam is obtained to demonstrate the steering performance with the respect to the incident laser beam power and beam waist.
Dobbs-Dixon, Ian
numerous published papers, further work is needed to couple them self-consistently. Our theoretical studies focus on a number of objectives. We will start by incorporating our kinetic, non-equilibrium cloud model within BART, allowing us to obtain a consistent solution for cloud characteristics. We will further test simple parameterizations against the full solution to explore the reliability of simpler models. Utilizing Drift-RHD, we will explore the role of horizontal advection on cloud distribution, investigate the validity of 1D retrievals by comparing them to selfconsistently generated 3D models, and develop a retrieval framework for wavelengthdependent phase-curves. TEA will be enhanced with additional databases and the inclusion of condensates, providing realistic initial cloudy-model for retrievals. To explore the importance of equilibrium chemistry and exclude non-plausible chemical compositions (often the outcome of many retrieval approaches) we will relax the assumption of non-equilibrium chemistry by utilizing an analytical chemical equilibrium approach in BART. To address observations, our OBS suit for generating synthetic observations will be adapted to interface with our models, allowing us to both compare to existing observations and make predictions for future observations. With these tools, we are particularly well suited to understand discriminants between classes of models and identifying which particular set of observations could most readily distinguish cloud constituents and temperature features. The proposed research is directly relevant to the Planetary Science and Astrophysics goals through furthering our understanding of compositions, dynamics, energetics, and chemical behaviors of exoplanetary atmospheres. In addition, to maximize NASA's investment and encourage open access, we have and will continue to make all of our codes public and available to the community throughout the course of the research.
THEORETICAL-MODEL FOR THE SCATTERING OF LIGHT BY DENTIN AND COMPARISON WITH MEASUREMENTS
ZIJP, [No Value; TENBOSCH, JJ
1993-01-01
A theoretical model of the scattering of light by dentin is presented. The model that results is a superposition of several scattering contributions, i.e., scattering by mineral crystals, collagen fibrils, and dentinal tubules. These tubules are oriented so that they cause an asymmetrical scattering
Lind, M. [Oersted - DTU, Kgs. Lyngby (Denmark)
2005-10-01
Multilevel Flow Modeling (MFM) has proven to be an effective modeling tool for reasoning about plant failure and control strategies and is currently exploited for operator support in diagnosis and on-line alarm analysis. Previous MFM research was focussed on representing goals and functions of process plants which generate, transform and distribute mass and energy. However, only a limited consideration has been given to the problems of modeling the control systems. Control functions are indispensable for operating any industrial plant. But modeling of control system functions has proven to be a more challenging problem than modeling functions of energy and mass processes. The problems were discussed by Lind and tentative solutions has been proposed but have not been investigated in depth until recently, partly due to the lack of an appropriate theoretical foundation. The purposes of the present report are to show that such a theoretical foundation for modeling goals and functions of control systems can be built from concepts and theories of action developed by Von Wright and to show how the theoretical foundation can be used to extend MFM with concepts for modeling control systems. The theoretical foundations has been presented in detail elsewhere by the present author without the particular focus on modeling control actions and MFM adopted here. (au)
Achievement Goals and Discrete Achievement Emotions: A Theoretical Model and Prospective Test
Pekrun, Reinhard; Elliot, Andrew J.; Maier, Markus A.
2006-01-01
A theoretical model linking achievement goals to discrete achievement emotions is proposed. The model posits relations between the goals of the trichotomous achievement goal framework and 8 commonly experienced achievement emotions organized in a 2 (activity/outcome focus) x 2 (positive/negative valence) taxonomy. Two prospective studies tested…
By-product mutualism and the ambiguous effects of harsher environments - A game-theoretic model
De Jaegher, Kris; Hoyer, Britta
2016-01-01
We construct two-player two-strategy game-theoretic models of by-product mutualism, where our focus lies on the way in which the probability of cooperation among players is affected by the degree of adversity facing the players. In our first model, cooperation consists of the production of a public
Model Predictive Engine Air-Ratio Control Using Online Sequential Relevance Vector Machine
Hang-cheong Wong
2012-01-01
Full Text Available Engine power, brake-specific fuel consumption, and emissions relate closely to air ratio (i.e., lambda among all the engine variables. An accurate and adaptive model for lambda prediction is essential to effective lambda control for long term. This paper utilizes an emerging technique, relevance vector machine (RVM, to build a reliable time-dependent lambda model which can be continually updated whenever a sample is added to, or removed from, the estimated lambda model. The paper also presents a new model predictive control (MPC algorithm for air-ratio regulation based on RVM. This study shows that the accuracy, training, and updating time of the RVM model are superior to the latest modelling methods, such as diagonal recurrent neural network (DRNN and decremental least-squares support vector machine (DLSSVM. Moreover, the control algorithm has been implemented on a real car to test. Experimental results reveal that the control performance of the proposed relevance vector machine model predictive controller (RVMMPC is also superior to DRNNMPC, support vector machine-based MPC, and conventional proportional-integral (PI controller in production cars. Therefore, the proposed RVMMPC is a promising scheme to replace conventional PI controller for engine air-ratio control.
Archer, Daniel E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hornback, Donald Eric [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Johnson, Jeffrey O. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Nicholson, Andrew D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Patton, Bruce W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Peplow, Douglas E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Miller, Thomas Martin [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Ayaz-Maierhafer, Birsen [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
2015-01-01
This report summarizes the findings of a two year effort to systematically assess neutron and gamma backgrounds relevant to operational modeling and detection technology implementation. The first year effort focused on reviewing the origins of background sources and their impact on measured rates in operational scenarios of interest. The second year has focused on the assessment of detector and algorithm performance as they pertain to operational requirements against the various background sources and background levels.
Lambert, C.; Virgili, A.; Pettex, E.; Delavenne, J.; Toison, V.; Blanck, A.; Ridoux, V.
2017-07-01
According to the European Union Habitats and Birds Directives, EU Member States must extend the Natura 2000 network to marine ecosystems, through the designation of Marine Protected Areas (MPAs). However, the initial status of cetacean and seabird communities across European waters is often poorly understood. It is assumed that an MPA is justified where at least 1% of the ;national population; of a species is present during at least part of its biological cycle. The aim of the present work was to use model-based cetacean and seabird distribution to assess the networks of existing Natura 2000 sites and offshore proposed areas of biological interest. The habitat models used here were Generalised Additive Models computed from aerial surveys observational data collected during the winter 2011-2012 and the summer 2012 across the English Channel, Bay of Biscay and north-western Mediterranean Sea. Based on these models, a ratio between species relative abundance predicted within each MPA and the total relative abundance predicted over the French Atlantic or Mediterranean marine regions was computed and compared to the 1% threshold. This assessment was conducted for winter and summer independently, providing information for assessing the relevance of individual MPAs and MPA networks at a seasonal scale. Our results showed that the existing network designed for coastal seabird species was relevant in both marine regions. In contrast, a clear shortfall was identified for offshore seabird species in the Atlantic region and for cetaceans in both regions. Moreover, the size of MPAs appeared to be a crucial feature, with larger MPAs being relevant for more species. Finally, we showed that the proposed large offshore areas of interest would constitute a highly relevant network for all offshore species, with e.g. up to 61% of the Globicephalinae population in the Atlantic French waters being present within these areas.
Can a snow structure model estimate snow characteristics relevant to reindeer husbandry?
Sirpa Rasmus
2014-02-01
Full Text Available Snow affects foraging conditions of reindeer e.g. by increasing the energy expenditures for moving and digging work or, in contrast, by making access of arboreal lichen easier. Still the studies concentrating on the role of the snow pack structure on reindeer population dynamics and reindeer management are few. We aim to find out which of the snow characteristics are relevant for reindeer in the northern boreal zone according to the experiences of reindeer herders and is this relevance seen also in reproduction rate of reindeer in this area. We also aim to validate the ability of the snow model SNOWPACK to reliably estimate the relevant snow structure characteristics. We combined meteorological observations, snow structure simulations by the model SNOWPACK and annual reports by reindeer herders during winters 1972-2010 in the Muonio reindeer herding district, northern Finland. Deep snow cover and late snow melt were the most common unfavorable conditions reported. Problematic conditions related to snow structure were icy snow and ground ice or unfrozen ground below the snow, leading to mold growth on ground vegetation. Calf production percentage was negatively correlated to the measured annual snow depth and length of the snow cover time and to the simulated snow density. Winters with icy snow could be distinguished in three out of four reported cases by SNOWPACK simulations and we could detect reliably winters with conditions favorable for mold growth. Both snow amount and also quality affects the reindeer herding and reindeer reproduction rate in northern Finland. Model SNOWPACK can relatively reliably estimate the relevant structural properties of snow. Use of snow structure models could give valuable information about grazing conditions, especially when estimating the possible effects of warming winters on reindeer populations and reindeer husbandry. Similar effects will be experienced also by other arctic and boreal species.
Cusack, Lynette; Smith, Morgan; Hegney, Desley; Rees, Clare S.; Breen, Lauren J.; Witt, Regina R.; Rogers, Cath; Williams, Allison; Cross, Wendy; Cheung, Kin
2016-01-01
Building nurses' resilience to complex and stressful practice environments is necessary to keep skilled nurses in the workplace and ensuring safe patient care. A unified theoretical framework titled Health Services Workplace Environmental Resilience Model (HSWERM), is presented to explain the environmental factors in the workplace that promote nurses' resilience. The framework builds on a previously-published theoretical model of individual resilience, which identified the key constructs of psychological resilience as self-efficacy, coping and mindfulness, but did not examine environmental factors in the workplace that promote nurses' resilience. This unified theoretical framework was developed using a literary synthesis drawing on data from international studies and literature reviews on the nursing workforce in hospitals. The most frequent workplace environmental factors were identified, extracted and clustered in alignment with key constructs for psychological resilience. Six major organizational concepts emerged that related to a positive resilience-building workplace and formed the foundation of the theoretical model. Three concepts related to nursing staff support (professional, practice, personal) and three related to nursing staff development (professional, practice, personal) within the workplace environment. The unified theoretical model incorporates these concepts within the workplace context, linking to the nurse, and then impacting on personal resilience and workplace outcomes, and its use has the potential to increase staff retention and quality of patient care. PMID:27242567
Cusack, Lynette; Smith, Morgan; Hegney, Desley; Rees, Clare S; Breen, Lauren J; Witt, Regina R; Rogers, Cath; Williams, Allison; Cross, Wendy; Cheung, Kin
2016-01-01
Building nurses' resilience to complex and stressful practice environments is necessary to keep skilled nurses in the workplace and ensuring safe patient care. A unified theoretical framework titled Health Services Workplace Environmental Resilience Model (HSWERM), is presented to explain the environmental factors in the workplace that promote nurses' resilience. The framework builds on a previously-published theoretical model of individual resilience, which identified the key constructs of psychological resilience as self-efficacy, coping and mindfulness, but did not examine environmental factors in the workplace that promote nurses' resilience. This unified theoretical framework was developed using a literary synthesis drawing on data from international studies and literature reviews on the nursing workforce in hospitals. The most frequent workplace environmental factors were identified, extracted and clustered in alignment with key constructs for psychological resilience. Six major organizational concepts emerged that related to a positive resilience-building workplace and formed the foundation of the theoretical model. Three concepts related to nursing staff support (professional, practice, personal) and three related to nursing staff development (professional, practice, personal) within the workplace environment. The unified theoretical model incorporates these concepts within the workplace context, linking to the nurse, and then impacting on personal resilience and workplace outcomes, and its use has the potential to increase staff retention and quality of patient care.
Xiaojin Li
2013-01-01
Full Text Available Previous studies have investigated both structural and functional brain networks via graph-theoretical methods. However, there is an important issue that has not been adequately discussed before: what is the optimal theoretical graph model for describing the structural networks of human brain? In this paper, we perform a comparative study to address this problem. Firstly, large-scale cortical regions of interest (ROIs are localized by recently developed and validated brain reference system named Dense Individualized Common Connectivity-based Cortical Landmarks (DICCCOL to address the limitations in the identification of the brain network ROIs in previous studies. Then, we construct structural brain networks based on diffusion tensor imaging (DTI data. Afterwards, the global and local graph properties of the constructed structural brain networks are measured using the state-of-the-art graph analysis algorithms and tools and are further compared with seven popular theoretical graph models. In addition, we compare the topological properties between two graph models, namely, stickiness-index-based model (STICKY and scale-free gene duplication model (SF-GD, that have higher similarity with the real structural brain networks in terms of global and local graph properties. Our experimental results suggest that among the seven theoretical graph models compared in this study, STICKY and SF-GD models have better performances in characterizing the structural human brain network.
Theoretical Models of Light Scattering Applied in Sizing Particles in Coal Water Slurry
王仁哲; 张荣曾; 徐志强
2004-01-01
Advantges and disadvantage of Mie scattering model and Fraunhofer diffraction model are discussed. The result shows that 1) the Fraunhofer diffraction model is simple in design and fast in operation, which is quite suitable for on-line control and 2) the intensity and energy distribution of diffracted light of both the Mie scattering model and the Fraunhofer theoretical model are compared and researched. Feasibility of using the Fraunhofer diffraction model to replace the Mie scattering model in measuring particles in coal water slurry is demonstrated.
Johnson, Marcus L.; Taasoobshirazi, Gita; Kestler, Jessica L.; Cordova, Jackie R.
2015-01-01
We tested a theoretical model of college students' ratings of messengers of resilience and models of resilience, students' own perceived resilience, regulatory strategy use and achievement. A total of 116 undergraduates participated in this study. The results of a path analysis indicated that ratings of models of resilience had a direct effect on…
Jennings, Karen M
2017-08-18
Using a nursing theoretical framework to understand, elucidate, and propose nursing research is fundamental to knowledge development. This article presents the Roy Adaptation Model as a theoretical framework to better understand individuals with anorexia nervosa during acute treatment, and the role of nursing assessments and interventions in the promotion of weight restoration. Nursing assessments and interventions situated within the Roy Adaptation Model take into consideration how weight restoration does not occur in isolation but rather reflects an adaptive process within external and internal environments, and has the potential for more holistic care.
Algebraic Specifications, Higher-order Types and Set-theoretic Models
Kirchner, Hélène; Mosses, Peter David
2001-01-01
In most algebraic specification frameworks, the type system is restricted to sorts, subsorts, and first-order function types. This is in marked contrast to the so-called model-oriented frameworks, which provide higer-order types, interpreted set-theoretically as Cartesian products, function spaces......, and power-sets. This paper presents a simple framework for algebraic specifications with higher-order types and set-theoretic models. It may be regarded as the basis for a Horn-clause approximation to the Z framework, and has the advantage of being amenable to prototyping and automated reasoning. Standard...
The theoretical development of the cascade model excimer laser irradiation on the organ of vision
V. N. Trubilin
2012-01-01
Full Text Available Authors analyzed the baseline (Pershin K. B., 2000 and advanced (trubilin V. N Pozharitskii M. D., 2011 theoretical model of the cascade excimer laser effects on eyesight.the analysis indicates a lack of elaboration of issues related to the cascade of «a priori measures» aimed at medical and psycho- logical prediction «quality of life» and post-operative rehabilitation. In theory, authors suggest further improvement of the cascade model of excimer laser irradiation on the organ of vision. the proposed theoretical concepts will provide a practical matter, improvefunctional and subjective results of the excimer laser correction of refractive errors.
Romain Morlhon
2015-01-01
Full Text Available Building Information Modeling (BIM has become a widely accepted tool to overcome the many hurdles that currently face the Architecture, Engineering and Construction industries. However, implementing such a system is always complex and the recent introduction of BIM does not allow organizations to build their experience on acknowledged standards and procedures. Moreover, data on implementation projects is still disseminated and fragmentary. The objective of this study is to develop an assistance model for BIM implementation. Solutions that are proposed will help develop BIM that is better integrated and better used, and take into account the different maturity levels of each organization. Indeed, based on Critical Success Factors, concrete activities that help in implementation are identified and can be undertaken according to the previous maturity evaluation of an organization. The result of this research consists of a structured model linking maturity, success factors and actions, which operates on the following principle: once an organization has assessed its BIM maturity, it can identify various weaknesses and find relevant answers in the success factors and the associated actions.
2016-06-01
Modeling Relevant to Safe Operations of U.S. Navy Vessels in Arctic Conditions.” The program manager was Dr. Paul Hess in Code 331, Structural...of Ice–Structure Interaction. Engineering Fracture Mechanics 68:1923–60. Jordaan, I. J., M. A. Maes, P. W. Brown, and I. P. Hermans . 1993
A Theoretical Extension of the Technology Acceptance Model: Four Longitudinal Field Studies
Viswanath Venkatesh; Fred D. Davis
2000-01-01
The present research develops and tests a theoretical extension of the Technology Acceptance Model (TAM) that explains perceived usefulness and usage intentions in terms of social influence and cognitive instrumental processes. The extended model, referred to as TAM2, was tested using longitudinal data collected regarding four different systems at four organizations (N = 156), two involving voluntary usage and two involving mandatory usage. Model constructs were measured at three points in ti...
Theoretical Model of User Acceptance: In the View of Measuring Success in Web Personalization
Amin, Mohd Afandi Md; Nayak, Richi
2010-01-01
International audience; This paper attempts to develop a theoretical acceptance model for measuring Web personalization success. Key factors impacting Web personalization acceptance are identified from a detailed literature review. The final model is then cast in a structural equation modeling (SEM) framework comprising nineteen manifest variables, which are grouped into three focal behaviors of Web users. These variables could provide a framework for better understanding of numerous factors ...
A theoretical extraction scheme of transport information based on exclusion models
Chen Hua; Du Lei; Qu Cheng-Li; Li Wei-Hua; He Liang; Chen Wen-Hao; Sun Peng
2010-01-01
In order to explore how to extract more transport information from current fluctuation, a theoretical extraction scheme is presented in a single barrier structure based on exclusion models, which include counter-flows model and tunnel model. The first four cumulants of these two exclusion models are computed in a single barrier structure, and their characteristics are obtained. A scheme with the help of the first three cumulants is devised to check a transport process to follow the counter-flows model, the tunnel model or neither of them. Time series generated by Monte Carlo techniques is adopted to validate the abstraction procedure, and the result is reasonable.
Two Models Relevant to the Interaction of a Point Charge and a Magnetic Moment
Boyer, Timothy H
2012-01-01
An understanding of the interaction of a point charge and a magnetic moment is crucial for understanding the experiments involving electromagnetic momentum carried by permeable materials as well as the experimentally-observed Aharonov-Bohm and Aharonov-Casher phase shifts. Here we present two simple models for a magnetic moment which have vastly different interactions with a distant point charge. It is suggested that a satisfactory theoretical understanding of the interaction is still lacking and that the "hidden momentum" interpretation has been introduced into the textbook literature prematurely.
Theoretical results on the tandem junction solar cell based on its Ebers-Moll transistor model
Goradia, C.; Vaughn, J.; Baraona, C. R.
1980-01-01
A one-dimensional theoretical model of the tandem junction solar cell (TJC) with base resistivity greater than about 1 ohm-cm and under low level injection has been derived. This model extends a previously published conceptual model which treats the TJC as an npn transistor. The model gives theoretical expressions for each of the Ebers-Moll type currents of the illuminated TJC and allows for the calculation of the spectral response, I(sc), V(oc), FF and eta under variation of one or more of the geometrical and material parameters and 1MeV electron fluence. Results of computer calculations based on this model are presented and discussed. These results indicate that for space applications, both a high beginning of life efficiency, greater than 15% AM0, and a high radiation tolerance can be achieved only with thin (less than 50 microns) TJC's with high base resistivity (greater than 10 ohm-cm).
A theoretical model to describe progressions and regressions for exercise rehabilitation.
Blanchard, Sam; Glasgow, Phil
2014-08-01
This article aims to describe a new theoretical model to simplify and aid visualisation of the clinical reasoning process involved in progressing a single exercise. Exercise prescription is a core skill for physiotherapists but is an area that is lacking in theoretical models to assist clinicians when designing exercise programs to aid rehabilitation from injury. Historical models of periodization and motor learning theories lack any visual aids to assist clinicians. The concept of the proposed model is that new stimuli can be added or exchanged with other stimuli, either intrinsic or extrinsic to the participant, in order to gradually progress an exercise whilst remaining safe and effective. The proposed model maintains the core skills of physiotherapists by assisting clinical reasoning skills, exercise prescription and goal setting. It is not limited to any one pathology or rehabilitation setting and can adapted by any level of skilled clinician.
Lee, Robert Mkw; Dickhout, Jeffrey G; Sandow, Shaun L
2017-04-01
Essential hypertension is a complex multifactorial disease process that involves the interaction of multiple genes at various loci throughout the genome, and the influence of environmental factors such as diet and lifestyle, to ultimately determine long-term arterial pressure. These factors converge with physiological signaling pathways to regulate the set-point of long-term blood pressure. In hypertension, structural changes in arteries occur and show differences within and between vascular beds, between species, models and sexes. Such changes can also reflect the development of hypertension, and the levels of circulating humoral and vasoactive compounds. The role of perivascular adipose tissue in the modulation of vascular structure under various disease states such as hypertension, obesity and metabolic syndrome is an emerging area of research, and is likely to contribute to the heterogeneity described in this review. Diversity in structure and related function is the norm, with morphological changes being causative in some beds and states, and in others, a consequence of hypertension. Specific animal models of hypertension have advantages and limitations, each with factors influencing the relevance of the model to the human hypertensive state/s. However, understanding the fundamental properties of artery function and how these relate to signalling mechanisms in real (intact) tissues is key for translating isolated cell and model data to have an impact and relevance in human disease etiology. Indeed, the ultimate aim of developing new treatments to correct vascular dysfunction requires understanding and recognition of the limitations of the methodologies used.
Walz, Yvonne; Wegmann, Martin; Leutner, Benjamin; Dech, Stefan; Vounatsou, Penelope; N'Goran, Eliézer K; Raso, Giovanna; Utzinger, Jürg
2015-01-01
Schistosomiasis is a widespread water-based disease that puts close to 800 million people at risk of infection with more than 250 million infected, mainly in sub-Saharan Africa. Transmission is governed by the spatial distribution of specific freshwater snails that act as intermediate hosts and the frequency, duration and extent of human bodies exposed to infested water sources during human water contact. Remote sensing data have been utilized for spatially explicit risk profiling of schistosomiasis. Since schistosomiasis risk profiling based on remote sensing data inherits a conceptual drawback if school-based disease prevalence data are directly related to the remote sensing measurements extracted at the location of the school, because the disease transmission usually does not exactly occur at the school, we took the local environment around the schools into account by explicitly linking ecologically relevant environmental information of potential disease transmission sites to survey measurements of disease prevalence. Our models were validated at two sites with different landscapes in Côte d'Ivoire using high- and moderate-resolution remote sensing data based on random forest and partial least squares regression. We found that the ecologically relevant modelling approach explained up to 70% of the variation in Schistosoma infection prevalence and performed better compared to a purely pixel-based modelling approach. Furthermore, our study showed that model performance increased as a function of enlarging the school catchment area, confirming the hypothesis that suitable environments for schistosomiasis transmission rarely occur at the location of survey measurements.
Hygge, S; Ohman, A
1978-03-01
Fear-relevant (snakes, spiders, and rats) and fear-irrelevant (flowers, mushrooms, and berries) pictures were compared as conditioned and instigating stimuli in a vicarious classical conditioning paradigm with skin conductance responses as the dependent variable. A female confederate model and subject watched the pictures side by side. A female stimulus presentations, the experimenter interrupted to investigate alleged overreactions of the model to one of the stimulus classes. The model then vividly described a phobia for this object, which was to serve as a vicarious instigating stimulus. The experiment continued for a few conditioning trials, and then the experimenter announced that the disturbing stimulus would be omitted before the second part of the experiment. There was no effect of stimulus content on vicariously instigated responses, although significant overall instigation was observed. However, the responses to the stimulus that was paired with the model's phobic stimulus, that is, the vicariously conditioned responses, failed to extinguish during the second part of the experiment when it was fear-relevant but extinguished immediately when it was fear-irrelevant.
A Physically Based Theoretical Model of Spore Deposition for Predicting Spread of Plant Diseases.
Isard, Scott A; Chamecki, Marcelo
2016-03-01
A physically based theory for predicting spore deposition downwind from an area source of inoculum is presented. The modeling framework is based on theories of turbulence dispersion in the atmospheric boundary layer and applies only to spores that escape from plant canopies. A "disease resistance" coefficient is introduced to convert the theoretical spore deposition model into a simple tool for predicting disease spread at the field scale. Results from the model agree well with published measurements of Uromyces phaseoli spore deposition and measurements of wheat leaf rust disease severity. The theoretical model has the advantage over empirical models in that it can be used to assess the influence of source distribution and geometry, spore characteristics, and meteorological conditions on spore deposition and disease spread. The modeling framework is refined to predict the detailed two-dimensional spatial pattern of disease spread from an infection focus. Accounting for the time variations of wind speed and direction in the refined modeling procedure improves predictions, especially near the inoculum source, and enables application of the theoretical modeling framework to field experiment design.
Piper, Llewellyn E
2006-01-01
This article proposes a theoretical model for leaders to use to address organizational human conflict and disruptive behavior in health care organizations. Leadership is needed to improve interpersonal relationships within the workforce. A workforce with a culture of internal conflict will be unable to achieve its full potential to delivery quality patient care.
Theoretical analysis of an iron mineral-based magnetoreceptor model in birds
Solov'yov, Ilia; Greiner, Walter
2007-01-01
involves two types of iron minerals (magnetite and maghemite) that were found in subcellular compartments within sensory dendrites of the upper beak of several bird species. But so far a quantitative evaluation of the proposed receptor is missing. In this article, we develop a theoretical model...
How Career Variety Promotes the Adaptability of Managers: A Theoretical Model
Karaevli, Ayse; Tim Hall, Douglas T.
2006-01-01
This paper presents a theoretical model showing how managerial adaptability develops from career variety over the span of the person's career. By building on the literature of career theory, adult learning and development, and career adjustment, we offer a new conceptualization of managerial adaptability by identifying its behavioral, cognitive,…
Validation of a Theoretical Model of Diagnostic Classroom Assessment: A Mixed Methods Study
Koh, Nancy
2012-01-01
The purpose of the study was to validate a theoretical model of diagnostic, formative classroom assessment called, "Proximal Assessment for Learner Diagnosis" (PALD). To achieve its purpose, the study employed a two-stage, mixed-methods design. The study utilized multiple data sources from 11 elementary level mathematics teachers who…
Toward a Theoretical Model of Learning As It Relates To Simulation Games With Discussion.
Chartier, Myron Raymond
In order for research on the educational utility of simultation games to advance, there must be some stipulation of a set of significant variables. This, in turn, requires the building of testable theoretical models and the formulation of strategic propositions to test their validity. An example of the process involved is as follows. Focusing upon…
INTELLIGENT CAR STYLING TECHNIQUE AND SYSTEM BASED ON A NEW AERODYNAMIC-THEORETICAL MODEL
无
2002-01-01
Car styling technique based on a new theoretical model of automotive aerodynamics is introduced, which is proved to be feasible and effective by wind tunnel tests. Development of a multi-module software system from this technique, including modules of knowledge processing, referential styling and ANN aesthetic evaluation etc, capable of assisting car styling works in an intelligent way, is also presented and discussed.
Balmer, Dorene F.; Richards, Boyd F.; Varpio, Lara
2015-01-01
Using Bourdieu's theoretical model as a lens for analysis, we sought to understand how students experience the undergraduate medical education (UME) milieu, focusing on how they navigate transitions from the preclinical phase, to the major clinical year (MCY), and to the preparation for residency phase. Twenty-two medical students participated in…
Unconscious Determinants of Career Choice and Burnout: Theoretical Model and Counseling Strategy.
Malach-Pines, Ayala; Yafe-Yanai, Oreniya
2001-01-01
Proposes a psychodynamic-existential perspective as a theoretical model that explains career burnout and serves as a basis for a counseling strategy. According to existential theory, the root of career burnout lies in people's need to find existential significance in their life and their sense that their work does not provide it. (Contains 40…
On the Grammar and Model-Theoretic Semantics of Children's Noun Phrases.
Suppes, Patrick
The paper shows informally how model-theoretical semantics may be used by a computer to give a straight-forward analysis of the meaning of children's language. This approach to semantics grows out of the main thrust of work in mathematical logic. It is discussed in the framework of generative grammar and is based on the application of the…
Briggs, Michele Kielty; Shoffner, Marie F.
2006-01-01
Overall spiritual wellness, as well as 4 individual components of spiritual wellness, has been theoretically and empirically linked with depression. Prior to this investigation, no study has examined the relationship between spiritual wellness and depression by using a 4-component measurement model of spiritual wellness. In this study of older…
E-Learning Systems Support of Collaborative Agreements: A Theoretical Model
Aguirre, Sandra; Quemada, Juan
2012-01-01
This paper introduces a theoretical model for developing integrated degree programmes through e-learning systems as stipulated by a collaboration agreement signed by two universities. We have analysed several collaboration agreements between universities at the national, European, and transatlantic level as well as various e-learning frameworks. A…
Models of the Bilingual Lexicon and Their Theoretical Implications for CLIL
Heine, Lena
2014-01-01
Although many advances have been made in recent years concerning the theoretical dimensions of content and language integrated learning (CLIL), research still has to meet the necessity to come up with integrative models that adequately map the interrelation between content and language learning in CLIL contexts. This article will suggest that…
Suggestion for a Theoretical Model for Secondary-Tertiary Transition in Mathematics
Clark, Megan; Lovric, Miroslav
2008-01-01
One of most notable features of existing body of research in transition seems to be the absence of a theoretical model. The suggestion we present in this paper--to view and understand the high school to university transition in mathematics as a modern-day rite of passage--is an attempt at defining such framework. Although dominantly reflecting…
Improvements on Calculation Model of Theoretical Combustion Temperature in a Blast Furnace
WU Sheng-li; LIU Cheng-song; FU Chang-liang; XU Jian; KOU Ming-yin
2011-01-01
On the basis of the existing originally modified calculation models of theoretical combustion temperature（TCT）,some factors,such as the combustion ratio of pulverized coal injection（PCI）,the decomposition heat of PCI and the heat consumption of SiO2 in ash reduced in high temperature environment,were amended and improved to put forward a more comprehensive model for calculating TCT.The influences of each improvement on TCT were studied and the results were analyzed compared with those of traditional model and originally modified model,which showed that the present model could reflect the thermal state of a hearth more effectively.
Gabere MN
2016-06-01
Full Text Available Musa Nur Gabere,1 Mohamed Aly Hussein,1 Mohammad Azhar Aziz2 1Department of Bioinformatics, King Abdullah International Medical Research Center/King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; 2Colorectal Cancer Research Program, Department of Medical Genomics, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia Purpose: There has been considerable interest in using whole-genome expression profiles for the classification of colorectal cancer (CRC. The selection of important features is a crucial step before training a classifier.Methods: In this study, we built a model that uses support vector machine (SVM to classify cancer and normal samples using Affymetrix exon microarray data obtained from 90 samples of 48 patients diagnosed with CRC. From the 22,011 genes, we selected the 20, 30, 50, 100, 200, 300, and 500 genes most relevant to CRC using the minimum-redundancy–maximum-relevance (mRMR technique. With these gene sets, an SVM model was designed using four different kernel types (linear, polynomial, radial basis function [RBF], and sigmoid.Results: The best model, which used 30 genes and RBF kernel, outperformed other combinations; it had an accuracy of 84% for both ten fold and leave-one-out cross validations in discriminating the cancer samples from the normal samples. With this 30 genes set from mRMR, six classifiers were trained using random forest (RF, Bayes net (BN, multilayer perceptron (MLP, naïve Bayes (NB, reduced error pruning tree (REPT, and SVM. Two hybrids, mRMR + SVM and mRMR + BN, were the best models when tested on other datasets, and they achieved a prediction accuracy of 95.27% and 91.99%, respectively, compared to other mRMR hybrid models (mRMR + RF, mRMR + NB, mRMR + REPT, and mRMR + MLP. Ingenuity pathway analysis was used to analyze the functions of the 30 genes selected for this model and their potential association with CRC: CDH3, CEACAM7, CLDN1, IL8, IL6R, MMP1
A theoretical model for Reynolds-stress and dissipation-rate budgets in near-wall region
陆利蓬; 陈矛章
2000-01-01
A 3-D wave model for the turbulent coherent structures in near-wall region is proposed. The transport nature of the Reynolds stresses and dissipation rate of the turbulence kinetic energy are shown via computation based on the theoretical model. The mean velocity profile is also computed by using the same theoretical model. The theoretical results are in good agreement with those found from DNS, indicating that the theoretical model proposed can correctly describe the physical mechanism of turbulence in near wail region and it thus possibly opens a new way for turbulence modeling in this region.
A theoretical model for Reynolds-stress and dissipation-rate budgets in near-wall region
无
2000-01-01
A 3-D wave model for the turbulent coherent structures in near-wall region is proposed. The transport nature of the Reynolds stresses and dissipation rate of the turbulence kinetic energy are shown via computation based on the theoretical model. The mean velocity profile is also computed by using the same theoretical model. The theoretical results are in good agreement with those found from DNS, indicating that the theoretical model proposed can correctly describe the physical mechanism of turbulence in near wall region and it thus possibly opens a new way for turbulence modeling in this region.
Stem cell therapy for joint problems using the horse as a clinically relevant animal model
Koch, Thomas Gadegaard; Betts, Dean H.
2007-01-01
of the developmental biology of synovial joints and their pathologies. Before human clinical trials are undertaken, stem cell-based therapies for non-life-threatening disorders should be evaluated for their safety and efficacy using animal models of spontaneous disease and not solely by the existing laboratory models...... of experimentally induced lesions. The horse lends itself as a good animal model of spontaneous joint disorders that are clinically relevant to similar human disorders. Equine stem cell and tissue engineering studies may be financially feasible to principal investigators and small biotechnology companies......Research into articular cartilage is a surprisingly recent endeavour and much remains to be learned about the normal development of the synovial joint and its components that interplay in osteoarthritis and focal cartilage defects. Stem cell research is likely to contribute to the understanding...
A clinically relevant mouse model of canine osteosarcoma with spontaneous metastasis.
Chaffee, Beth K; Allen, Matthew J
2013-01-01
Many patients with osteosarcoma (OS) will succumb to distant metastasis, often involving the lungs. Effective therapies for treating lung metastases depend on the availability of a clinically relevant pre-clinical model. Mice were surgically implanted with OS tumor fragments. The time course of primary tumor growth and subsequent spread to the lung were determined. Following development of a lytic and proliferative primary bone lesion, tumor metastasized to the lung in the majority of mice. There was no evidence of tumor at three weeks, but 10 out of 11 mice ultimately developed secondary OS in the lung within 12 weeks. Implantation of OS tumor fragments leads to the development of primary bone tumors and secondary lung metastases, recapitulating the clinical behavior of OS. This model offers an advantage over cell suspension injection models by precluding initial seeding of the lung with tumor cells.
Tosini, Gianluca; Owino, Sharon; Guillaume, Jean-Luc; Jockers, Ralf
2014-08-01
Melatonin, the neuro-hormone synthesized during the night, has recently seen an unexpected extension of its functional implications toward type 2 diabetes development, visual functions, sleep disturbances, and depression. Transgenic mouse models were instrumental for the establishment of the link between melatonin and these major human diseases. Most of the actions of melatonin are mediated by two types of G protein-coupled receptors, named MT1 and MT2 , which are expressed in many different organs and tissues. Understanding the pharmacology and function of mouse MT1 and MT2 receptors, including MT1 /MT2 heteromers, will be of crucial importance to evaluate the relevance of these mouse models for future therapeutic developments. This review will critically discuss these aspects, and give some perspectives including the generation of new mouse models.
Relevant Criteria for Testing the Quality of Models for Turbulent Wind Speed Fluctuations
Frandsen, Sten Tronæs; Ejsing Jørgensen, Hans; Sørensen, John Dalsgaard
2008-01-01
-size wind turbines when seeking wind characteristics that correspond to one blade and the entire rotor, respectively. For heights exceeding 50-60 m, the gust factor increases with wind speed. For heights larger than 60-80 m, present assumptions on the value of the gust factor are significantly......Seeking relevant criteria for testing the quality of turbulence models, the scale of turbulence and the gust factor have been estimated from data and compared with predictions from first-order models of these two quantities. It is found that the mean of the measured length scales is approximately...... 10% smaller than the IEC model for wind turbine hub height levels. The mean is only marginally dependent on trends in time series. It is also found that the coefficient of variation of the measured length scales is about 50%. 3 s and 10 s preaveraging of wind speed data are relevant for megawatt...
GRAPH THEORETICAL AND NETWORKS APPROACH FOR THE DEVELOPMENT OF A LEARNING MODEL – A CASE STUDY
PROF. DR. P. K. SRIMANI
2012-08-01
Full Text Available This paper deals with the graph theoretical approach for developing a framework for the Learning model used to optimise the Mathematical Pathway in children at the elementary level and verifying it by usingNetworks model. Data collected pertaining to the mathematical concepts a child needs to learn at elementary level [Class I to VII] is represented by using Concept Flow Graphs and are optimized by using graph theory techniques and algorithms by rearranging nodes as per the learning progression, partitioning the graphs into subgraphsto represent levels of learning, optimizing the sub-graphs using merging and elimination technique and identifying / marking the optional nodes. The design of the framework by using the graph theoretical approach is validated by the application of the Networks approach and this is used to design the Mathematical Pathwaydriver which is the core component of the Learning model. This approach is novel and the Learning model developed is highly accurate.
Study on Theoretical Modeling of Semi-Active Electro-Rheological Fluid Damper
饶柱石; 傅志方; 张华良
2003-01-01
This paper emphases on analyzing and investigating the mechanical behavior of electro-rheological fluid (ERF) semi-active damper. Theoretical model was developed to describe the relationship between electric field and the resistance force of ERF flowing through two parallel plane electrodes. In the model, the pressure drop along electrodes was supposed to consist of two parts: one related with viscosity and the other related with dynamic yield shear stress. The concept of yield stress in fluence factor was developed inderiving the theoretical formula for calculating the pressure drop in the damper. The influences of some other factors, such as, nonideal Newtonian fluid and temperature have also been taken into account. Numerical and experimental work have been performed to prove the validity of the proposed model. The comparison of both results shows that the developed model is quite effective and practicable.
Agha Mohammad Ali Kermani, Mehrdad; Fatemi Ardestani, Seyed Farshad; Aliahmadi, Alireza; Barzinpour, Farnaz
2017-01-01
Influence maximization deals with identification of the most influential nodes in a social network given an influence model. In this paper, a game theoretic framework is developed that models a competitive influence maximization problem. A novel competitive influence model is additionally proposed that incorporates user heterogeneity, message content, and network structure. The proposed game-theoretic model is solved using Nash Equilibrium in a real-world dataset. It is shown that none of the well-known strategies are stable and at least one player has the incentive to deviate from the proposed strategy. Moreover, violation of Nash equilibrium strategy by each player leads to their reduced payoff. Contrary to previous works, our results demonstrate that graph topology, as well as the nodes' sociability and initial tendency measures have an effect on the determination of the influential node in the network.
Monsivais, Diane B
2011-06-01
This article reviews the culture of biomedicine and current practices in pain management education, which often merge to create a hostile environment for effective chronic pain care. Areas of cultural tensions in chronic pain frequently involve the struggle to achieve credibility regarding one's complaints of pain (or being believed that the pain is real) and complying with pain medication protocols. The clinically relevant continuum model is presented as a framework allowing providers to approach care from an evidence-based, culturally appropriate (patient centered) perspective that takes into account the highest level of evidence available, provider expertise, and patient preferences and values. Copyright © 2011 Elsevier Inc. All rights reserved.
Theoretic model of myocardial revascularization by far Infrared laser and experimental validation
LUO Le; CHEN Xing; ZHANG Ting; ZONG Ren-he; DENG Shan-xi
2009-01-01
A theoretic model of myocardial revascularization by a far infrared laser has been established and a quantificational rela-tionship between the aperture of laser channel and parameters of laser has been concluded according to thermodynamics and the law of mteraction of far infrared laser and myocardium. The experiment of a carbon dioxide laser revascularization in porcine myocardinm has been done for different laser powers and irradiation time. The relative errors between experi-mental result and theoretic computation are from 13% to 22%. The reasons that cause the errors have been studied in detail.
Rational Design of Lanthanoid Single-Ion Magnets: Predictive Power of the Theoretical Models.
Baldoví, José J; Duan, Yan; Morales, Roser; Gaita-Ariño, Alejandro; Ruiz, Eliseo; Coronado, Eugenio
2016-09-12
We report two new single-ion magnets (SIMs) of a family of oxydiacetate lanthanide complexes with D3 symmetry to test the predictive capabilities of complete active space ab initio methods (CASSCF and CASPT2) and the semiempirical radial effective charge (REC) model. Comparison of the theoretical predictions of the energy levels, wave functions and magnetic properties with detailed spectroscopic and magnetic characterisation is used to critically discuss the limitations of these theoretical approaches. The need for spectroscopic information for a reliable description of the properties of lanthanide SIMs is emphasised.
Evarestov, RA
2015-01-01
This book deals with the theoretical and computational simulation of monoperiodic nanostructures for different classes of inorganic substances. These simulations are related to their synthesis and experimental studies. A theoretical formalism is developed to describe 1D nanostructures with symmetric shapes and morphologies. Three types of models are considered for this aim: (i) nanotubes (rolled from 2D nanolayers and described within the formalism of line symmetry groups); (ii) nanoribbons (obtained from 2D nanolayers by their cutting along the chosen direction of translation); (iii) nanowire
Adams, Matthew P.; Collier, Catherine J.; Uthicke, Sven; Ow, Yan X.; Langlois, Lucas; O’Brien, Katherine R.
2017-01-01
When several models can describe a biological process, the equation that best fits the data is typically considered the best. However, models are most useful when they also possess biologically-meaningful parameters. In particular, model parameters should be stable, physically interpretable, and transferable to other contexts, e.g. for direct indication of system state, or usage in other model types. As an example of implementing these recommended requirements for model parameters, we evaluated twelve published empirical models for temperature-dependent tropical seagrass photosynthesis, based on two criteria: (1) goodness of fit, and (2) how easily biologically-meaningful parameters can be obtained. All models were formulated in terms of parameters characterising the thermal optimum (Topt) for maximum photosynthetic rate (Pmax). These parameters indicate the upper thermal limits of seagrass photosynthetic capacity, and hence can be used to assess the vulnerability of seagrass to temperature change. Our study exemplifies an approach to model selection which optimises the usefulness of empirical models for both modellers and ecologists alike.
Rodent models of ischemic stroke lack translational relevance... are baboon models the answer?
Kwiecien, Timothy D; Sy, Christopher; Ding, Yuchuan
2014-05-01
Rodent models of ischemic stroke are associated with many issues and limitations, which greatly diminish the translational potential of these studies. Recent studies demonstrate that significant differences exist between rodent and human ischemic stroke. These differences include the physical characteristics of the stroke, as well as changes in the subsequent inflammatory and molecular pathways following the acute ischemic insult. Non-human primate (NHP) models of ischemic stroke, however, are much more similar to humans. In addition to evident anatomical similarities, the physiological responses that NHPs experience during ischemic stroke are much more applicable to the human condition and thus make it an attractive model for future research. The baboon ischemic stroke model, in particular, has been studied extensively in comparison to other NHP models. Here we discuss the major shortcomings associated with rodent ischemic stroke models and provide a comparative overview of baboon ischemic stroke models. Studies have shown that baboons, although more difficult to obtain and handle, are more representative of ischemic events in humans and may have greater translational potential that can offset these deficiencies. There remain critical issues within these baboon stroke studies that need to be addressed in future investigations. The most critical issue revolves around the size and the variability of baboon ischemic stroke. Compared to rodent models, however, issues such as these can be addressed in future studies. Importantly, baboon models avoid many drawbacks associated with rodent models including vascular variability and inconsistent inflammatory responses - issues that are inherent to the species and cannot be avoided.
Identifying Tipping Points in a Decision-Theoretic Model of Network Security
Heimann, C. F. Larry; Nochenson, Alan
2012-01-01
Although system administrators are frequently urged to protect the machines in their network, the fact remains that the decision to protect is far from universal. To better understand this decision, we formulate a decision-theoretic model of a system administrator responsible for a network of size n against an attacker attempting to penetrate the network and infect the machines with a virus or similar exploit. By analyzing the model we are able to demonstrate the cost sensitivity of smaller n...
A Theoretical Approach to Financial Therapy: The Development of the Ford Financial Empowerment Model
Kristy L. Archuleta; Joyce A. Baptist; Megan R. Ford
2012-01-01
The purpose of this paper is to introduce an integrative approach to working with clients experiencing problems related to financial disempowerment. The multi-phase model integrates three theoretically-driven psychotherapy approaches, including cognitive behavioral, narrative, and Virginia Satir’s experiential therapies, and financial counseling techniques to increase one’s sense of financial empowerment. A case study is included to demonstrate the applicability and effectiveness of the model...
Family Leadership: Constructing and Testing a Theoretical Model of Family Well-Being
Galbraith, Kevin A.
2000-01-01
Leadership in organizational contexts has received considerable attention through the years. Although much is known about what constitutes effective leadership in an organizational setting, little is known about leadership as it pertains to the family. To address this limitation, a theoretical model of family leadership was developed. This model draws on transformational leadership and proposes five areas in which leadership could be carried out to lead and strengthen the family unit. These f...
Experiments to test theoretical models of the polarization of light by rough surfaces
Geake, J. E.; Geake, M.; Zellner, B. H.
1984-01-01
A number of attempts have been made to provide theoretical models of the physical processes involved in the polarization of light scattered by a rough surface, such as the regolith of an atmosphereless planet. Some laboratory experiments designed to test different aspects of these models are described. It is concluded that double Fresnel reflection is usually the dominant process in producing negative polarization, but that diffraction effects may play a significant part in double events involving small-scale surface features.
A Theoretical Approach to Financial Therapy: The Development of the Ford Financial Empowerment Model
Kristy L. Archuleta; Joyce A. Baptist; Megan R. Ford
2012-01-01
The purpose of this paper is to introduce an integrative approach to working with clients experiencing problems related to financial disempowerment. The multi-phase model integrates three theoretically-driven psychotherapy approaches, including cognitive behavioral, narrative, and Virginia Satir’s experiential therapies, and financial counseling techniques to increase one’s sense of financial empowerment. A case study is included to demonstrate the applicability and effectiveness of the model...
Dias, Natália Martins; Gomes,Cristiano Mauro Assis; Reppold, Caroline Tozzi; Fioravanti-Bastos, Ana Carolina; Pires,Emmy Uehara; Carreiro, Luiz Renato Rodrigues; SEABRA,Alessandra Gotuzo
2015-01-01
Despite relative consensus on the existence of three basic executive functions (EF) (inhibition, working memory and cognitive flexibility) there is narrower knowledge on its organization and contribution to task solution. The study tested different theoretical models about the structure and composition of EF. The correlation matrix of Miyake et al. (2000), which evaluated university students in a set of 15 EF tasks, was adopted. Model 1 displays a general factor and specific components. In mo...
Yarkony, D.R. [Johns Hopkins Univ., Baltimore, MD (United States)
1993-12-01
This research program focusses on studies of spin-forbidden and electronically nonadiabatic processes involving radical species relevant to combustion reactions and combustion diagnostics. To study the electronic structure aspects of these processes a unique and powerful system of electronic structure programs, developed over the past nine years, the BROOKLYN codes, is employed. These programs enable the authors to address questions basic to the understanding of elementary combustion processes not tractable using more standard quantum chemistry codes.
Timpka, T; Eriksson, H; Holm, E; Strömgren, M; Ekberg, J; Spreco, A; Dahlström, Ö
2016-07-01
Workplaces are one of the most important regular meeting places in society. The aim of this study was to use simulation experiments to examine the impact of different workplace cultures on influenza dissemination during pandemics. The impact is investigated by experiments with defined social-mixing patterns at workplaces using semi-virtual models based on authentic sociodemographic and geographical data from a North European community (population 136 000). A simulated pandemic outbreak was found to affect 33% of the total population in the community with the reference academic-creative workplace culture; virus transmission at the workplace accounted for 10·6% of the cases. A model with a prevailing industrial-administrative workplace culture generated 11% lower incidence than the reference model, while the model with a self-employed workplace culture (also corresponding to a hypothetical scenario with all workplaces closed) produced 20% fewer cases. The model representing an academic-creative workplace culture with restricted workplace interaction generated 12% lower cumulative incidence compared to the reference model. The results display important theoretical associations between workplace social-mixing cultures and community-level incidence rates during influenza pandemics. Social interaction patterns at workplaces should be taken into consideration when analysing virus transmission patterns during influenza pandemics.
Burns, B.A.
1980-11-01
This report reviews social and behavioral science models and techniques for their possible use in understanding and predicting consumer energy decision making and behaviors. A number of models and techniques have been developed that address different aspects of the decision process, use different theoretical bases and approaches, and have been aimed at different audiences. Three major areas of discussion were selected: (1) models of adaptation to social change, (2) decision making and choice, and (3) diffusion of innovation. Within these three areas, the contributions of psychologists, sociologists, economists, marketing researchers, and others were reviewed. Five primary components of the models were identified and compared. The components are: (1) situational characteristics, (2) product characteristics, (3) individual characteristics, (4) social influences, and (5) the interaction or decision rules. The explicit use of behavioral and social science models in energy decision-making and behavior studies has been limited. Examples are given of a small number of energy studies which applied and tested existing models in studying the adoption of energy conservation behaviors and technologies, and solar technology.
A Relevance-Theoretic Analysis to Metonymy:An Issue of Pragmatic Interpretation%从关联理论看转喻的语用阐释
毛峻凌
2016-01-01
认知语言学从概念结构的角度研究转喻，对其概念化本质和指称功能做出了比较系统的描述和解读。文章在关联理论的指导下，以语言形式和关联性之间的内在关系为基础，从认知语用视角探讨动态语境中转喻的语用特征和推理过程，揭示言语交际过程中转喻的关联阐释及其体现的创造性。%In the framework of cognitive linguistics,metonymy is explored with regard to conceptual structure.The conceptualized nature and referential function are described and explained systematically.With relevance theory,the pragmatic features and the process of inference of metonymy in the dynamic contexts are analyzed from a cognitive pragmatic view,based on the interior relation between language form and relevance.It aims to reveal the relevant interpretation in verbal communication and the creativity it presents.
Greenwood-Van Meerveld, Beverley; Prusator, Dawn K; Johnson, Anthony C
2015-06-01
Visceral pain describes pain emanating from the thoracic, pelvic, or abdominal organs. In contrast to somatic pain, visceral pain is generally vague, poorly localized, and characterized by hypersensitivity to a stimulus such as organ distension. Animal models have played a pivotal role in our understanding of the mechanisms underlying the pathophysiology of visceral pain. This review focuses on animal models of visceral pain and their translational relevance. In addition, the challenges of using animal models to develop novel therapeutic approaches to treat visceral pain will be discussed. Copyright © 2015 the American Physiological Society.
无
2002-01-01
In this paper, a theoretical and numerical as-sessment of the validity of Eulerian truncation in stochastic modeling is presented. Specifically, we analyze and compare theoretically various existing Eulerian-based first-order tech-niques with and without invoking "Eulerian truncation" and quantify the terms truncated and retained in the stochastic per-turbation equations using high resolution Monte Carlo simula-tions. We also analyze and compare numerically various exist-ing Eulerian-based first-order techniques and Monte Carlo simulation. The obtained results have demonstrated theoreti-cally and numerically that existing Eulerian-based stochastic perturbation techniques are equivalent. The terms truncated are indeed one order higher than those retained. Therefore,we conclude that "Eulerian truncation" is mathematically con-sistent and asymptotic.
Okawada, Manabu; Wilson, Michael W; Larsen, Scott D; Lipka, Elke; Hillfinger, John; Teitelbaum, Daniel H
2016-12-01
Blockade of the renin-angiotensin system (RAS) has been shown to alleviate inflammatory processes in the gastrointestinal tract. The aim of this study was to determine if blockade of the RAS would be effective in an immunologically relevant colitis model, and to compare outcome with an acute colitis model. A losartan analog, CCG-203025 (C23H26ClN3O5S) containing a highly polar sulfonic acid moiety that we expected would allow localized mucosal antagonism with minimal systemic absorption was selected as an angiotensin II type 1a receptor antagonist (AT1aR-A). Two colitis models were studied: (1) Acute colitis was induced in 8- to 10-week-old C57BL/6J mice by 2.5 % dextran sodium sulfate (DSS, in drinking water) for 7 days. (2) IL10-/-colitis Piroxicam (200 ppm) was administered orally in feed to 5-week-old IL-10-/-mice (C57BL/6J background) for 14 days followed by enalaprilat (ACE-I), CCG-203025 or PBS administered transanally for 14 days. In the DSS model, weight loss and histologic score for CCG-203025 were better than with placebo. In the IL10-/-model, ACE-I suppressed histologic damage better than CCG-203025. Both ACE-I and CCG-203025 reduced pro-inflammatory cytokines and chemokines. This study demonstrated the therapeutic efficacy of both ACE-I and AT1aR-A for preventing the development of both acute and immunologically relevant colitis.
Budhwani, Karim Ismail
The tremendous quality of life impact notwithstanding, cardiovascular diseases and Cancer add up to over US$ 700bn each year in financial costs alone. Aging and population growth are expected to further expand the problem space while drug research and development remain expensive. However, preclinical costs can be substantially mitigated by substituting animal models with in vitro devices that accurately model human cardiovascular transport. Here we present a novel physiologically relevant lab-on-a-brane that simulates in vivo pressure, flow, strain, and shear waveforms associated with normal and pathological conditions in large and small blood vessels for studying molecular transport across the endothelial monolayer. The device builds upon previously demonstrated integrated microfluidic loop design by: (a) introducing nanoscale pores in the substrate membrane to enable transmembrane molecular transport, (b) transforming the substrate membrane into a nanofibrous matrix for 3D smooth muscle cell (SMC) tissue culture, (c) integrating electrospinning fabrication methods, (d) engineering an invertible sandwich cell culture device architecture, and (e) devising a healthy co-culture mechanism for human arterial endothelial cell (HAEC) monolayer and multiple layers of human smooth muscle cells (HSMC) to accurately mimic arterial anatomy. Structural and mechanical characterization was conducted using confocal microscopy, SEM, stress/strain analysis, and infrared spectroscopy. Transport was characterized using FITC-Dextran hydraulic permeability protocol. Structure and transport characterization successfully demonstrate device viability as a physiologically relevant arterial mimic for testing transendothelial transport. Thus, our lab-on-a-brane provides a highly effective and efficient, yet considerably inexpensive, physiologically relevant alternative for pharmacokinetic evaluation; possibly reducing animals used in pre-clinical testing, clinical trials cost from false
Establishment and Validation for the Theoretical Model of the Vehicle Airbag
ZHANG Junyuan; JIN Yang; XIE Lizhe; CHEN Chao
2015-01-01
The current design and optimization of the occupant restralnt system (ORS) are based on numerous actual tests and mathematic simulations. These two methods are overly time-consuming and complex for the concept design phase of the ORS, though they’re quite effective and accurate. Therefore, a fast and directive method of the design and optimization is needed in the concept design phase of the ORS. Since the alrbag system is a crucial part of the ORS, in this paper, a theoretical model for the vehicle alrbag is established in order to clarify the interaction between occupants and alrbags, and further a fast design and optimization method of alrbags in the concept design phase is made based on the proposed theoretical model. First, the theoretical expression of the simplified mechanical relationship between the alrbag’s design parameters and the occupant response is developed based on classical mechanics, then the momentum theorem and the ideal gas state equation are adopted to illustrate the relationship between alrbag’s design parameters and occupant response. By using MATLAB software, the iterative algorithm method and discrete variables are applied to the solution of the proposed theoretical model with a random input in a certaln scope. And validations by MADYMO software prove the validity and accuracy of this theoretical model in two principal design parameters, the inflated gas mass and vent diameter, within a regular range. This research contributes to a deeper comprehension of the relation between occupants and alrbags, further a fast design and optimization method for alrbags’ principal parameters in the concept design phase, and provides the range of the alrbag’s initial design parameters for the subsequent CAE simulations and actual tests.
Establishment and validation for the theoretical model of the vehicle airbag
Zhang, Junyuan; Jin, Yang; Xie, Lizhe; Chen, Chao
2015-05-01
The current design and optimization of the occupant restraint system (ORS) are based on numerous actual tests and mathematic simulations. These two methods are overly time-consuming and complex for the concept design phase of the ORS, though they're quite effective and accurate. Therefore, a fast and directive method of the design and optimization is needed in the concept design phase of the ORS. Since the airbag system is a crucial part of the ORS, in this paper, a theoretical model for the vehicle airbag is established in order to clarify the interaction between occupants and airbags, and further a fast design and optimization method of airbags in the concept design phase is made based on the proposed theoretical model. First, the theoretical expression of the simplified mechanical relationship between the airbag's design parameters and the occupant response is developed based on classical mechanics, then the momentum theorem and the ideal gas state equation are adopted to illustrate the relationship between airbag's design parameters and occupant response. By using MATLAB software, the iterative algorithm method and discrete variables are applied to the solution of the proposed theoretical model with a random input in a certain scope. And validations by MADYMO software prove the validity and accuracy of this theoretical model in two principal design parameters, the inflated gas mass and vent diameter, within a regular range. This research contributes to a deeper comprehension of the relation between occupants and airbags, further a fast design and optimization method for airbags' principal parameters in the concept design phase, and provides the range of the airbag's initial design parameters for the subsequent CAE simulations and actual tests.
A review of game-theoretic models of road user behaviour.
Elvik, Rune
2014-01-01
This paper reviews game-theoretic models that have been developed to explain road user behaviour in situations where road users interact with each other. The paper includes the following game-theoretic models: 1.A general model of the interaction between road users and their possible reaction to measures improving safety (behavioural adaptation).2.Choice of vehicle size as a Prisoners’ dilemma game.3.Speed choice as a co-ordination game.4.Speed compliance as a game between drivers and the police.5.Merging into traffic from an acceleration lane as a mixed-strategy game.6.Choice of level of attention in following situations as an evolutionary game.7.Choice of departure time to avoid congestion as variant of a Prisoners’ dilemma game.8.Interaction between cyclists crossing the road and car drivers.9.Dipping headlights at night well ahead of the point when glare becomes noticeable.10.Choice of evasive action in a situation when cars are on collision course. The models reviewed are different in many respects, but a common feature of the models is that they can explain how informal norms of behaviour can develop among road users and be sustained even if these informal norms violate the formal regulations of the traffic code. Game-theoretic models are not applicable to every conceivable interaction between road users or to situations in which road users choose behaviour without interacting with other road users. Nevertheless, it is likely that game-theoretic models can be applied more widely than they have been until now.
Sharma, S. K.
2012-12-01
A number of experimental elastic light scattering studies have been performed in the past few years with the aim of developing automated in vivo tools for differentiating a healthy red blood cell from a Plasmodium falciparum infected cell. This paper examines some theoretical aspects of the problem. An attempt has been made to simulate the scattering patterns of healthy as well as infected individual red blood cells. Two models, namely, a homogeneous sphere model and a coated sphere model have been considered. The scattering patterns predicted by these models are examined. A possible method for discriminating infected red blood cells from healthy ones has been suggested.
Theoretical models of pentamidine analogs activity based on their DNA minor groove complexes.
Zołek, Teresa; Maciejewska, Dorota
2010-05-01
The B-DNA binding property of pentamidine analogs was analyzed employing molecular dynamic simulations and UV-vis absorption spectroscopy. Their AATT and ATAT sequence preferences were also examined. In theoretical energy computations, we considered two solvation models: the implicit model I, where the solvent is characterized by a dielectric constant and the explicit model E, where water molecules are treated as discrete entities. The binding energy correlates well with the increase of melting temperature of the 5'-d(CGCGAATTCGCG)(2)-3' and 5'-d(CGCGATATCGCG)(2)-3' dodecamers after complexation with ligands (DeltaTm), and deduced models predicted adequately the DNA affinities of the studied diamidines.
Scarinci, Isabel C; Bandura, Lisa; Hidalgo, Bertha; Cherrington, Andrea
2012-01-01
The development of efficacious theory-based, culturally relevant interventions to promote cervical cancer prevention among underserved populations is crucial to the elimination of cancer disparities. The purpose of this article is to describe the development of a theory-based, culturally relevant intervention focusing on primary (sexual risk reduction) and secondary (Pap smear) prevention of cervical cancer among Latina immigrants using intervention mapping (IM). The PEN-3 and Health Belief Model provided theoretical guidance for the intervention development and implementation. IM provides a logical five-step framework in intervention development: delineating proximal program objectives, selecting theory-based intervention methods and strategies, developing a program plan, planning for adoption in implementation, and creating evaluation plans and instruments. We first conducted an extensive literature review and qualitatively examined the sociocultural factors associated with primary and secondary prevention of cervical cancer. We then proceeded to quantitatively validate the qualitative findings, which led to development matrices linking the theoretical constructs with intervention objectives and strategies as well as evaluation. IM was a helpful tool in the development of a theory-based, culturally relevant intervention addressing primary and secondary prevention among Latina immigrants.
Minodora Maria PASARE
2014-05-01
Full Text Available In this paper is about of the Hays-Kendall theoretical model of testing the microhardness of the composites materials of NiP/SiC type. We used an indenter to establish the microhardness of the composite and different types of loads. The microhardness can be interpreted using a theoretical model Hays-Kendall and the Kick model.
Gerhards, Helene; Jongsma, Karin; Schicktanz, Silke
2017-07-11
Trust within organizations is important for ensuring members' acceptance of the organization's activities and to expand their scope of action. Remarkably, Patient Organizations (POs) that often both function as a forum for self-help and represent patients on the health-political level, have been understudied in this respect. This paper analyzes the relation between trust and representation in POs. We distinguish between two models of representation originating from political theory: the trustee and delegate model and between two types of trust: horizontal and vertical trust. Our theoretical approach is illustrated with an analysis of 13 interviews with representatives of German POs. We have found that the delegate model requires horizontal trust and the trustee model vertical trust. Both models: horizontal/delegate and vertical/trustee exist within single POs. The representation process within POs demands a balancing act between inclusion of affected persons and strategically aggregating a clear-cut political claim. Trust plays in that process of coming from individual wishes to collective and political standpoints a major role both in terms of horizontal as well as vertical trust. Horizontal trust serves the communication between affected members, and vertical trust allows representatives to be decisive.
周又和; 郑晓静
1999-01-01
The quantitative analysis shows that no theoretical model for 3-d magnetoelastic bodies, in literatures to date, can commonly simulate two kinds of distinct experimental phenomena on magnetoelastic interaction of ferromagnetic structures. This makes it difficult to effectively discribe the magnetoelastic mechanical behavior of structures with complex geometry, such as shells. Therefore, it is a key step for simulating magnetoelastic mechanical characteristics of structures with complex geometry to establish a 3-d model which also can commonly characterize the two distinct experimental phenomena. A theoretical model for three dimension magnetizable elastic bodies, which is commonly suitable for the two kinds of experimental phenomena on magnetoelastic interaction of ferromagnetic plates, is presented by the variational principle for the total energy functional of the coupling system of the 3-d ferromagnetic bodies. It is found that for the case of linear isotropic magnetic materials, the magnetic forces
Ahlroth, S.
2001-01-01
This licentiate thesis tries to bridge the gap between the theoretical and the practical studies in the field of environmental accounting. In the paper, 1 develop an optimal control theory model for adjusting NDP for the effects Of SO{sub 2} and NO{sub x} emissions, and subsequently insert empirically estimated values. The model includes correction entries for the effects on welfare, real capital, health and the quality and quantity of renewable natural resources. In the empirical valuation study, production losses were estimated with dose-response functions. Recreational and other welfare values were estimated by the contingent valuation (CV) method. Effects on capital depreciation are also included. For comparison, abatement costs and environmental protection expenditures for reducing sulfur and nitrogen emissions were estimated. The theoretical model was then utilized to calculate the adjustment to NDP in a consistent manner.
A THEORETICAL MODEL OF SUPPORTING OPEN SOURCE FRONT END INNOVATION THROUGH IDEA MANAGEMENT
Aagaard, Annabeth
2013-01-01
Abstract: Most industries face continuing pressures from rising R&D costs, shortening product lifecycles and global competition. These challenges have increased the focus on shortening development times, which again puts pressure on the efficiency of front end innovation (FEI). In the attempt...... to overcome these various challenges companies are looking for new models to support FEI. This theoretical paper explores in what way idea management may be applied as a tool in facilitation of front end innovation and how this facilitation may be captured in a conceptual model. First, I show through...... a literature study, how idea management and front end innovation are related and how they may support each other. Secondly, I present a theoretical model of how idea management may be applied in support of the open source front end of new product innovations. Thirdly, I present different venues of further...
Sub-millimeter Spatial Oscillations of Newton's Constant: Theoretical Models and Laboratory Tests
Perivolaropoulos, Leandros
2016-01-01
We investigate the viability of sub-millimeter wavelength oscillating deviations from the Newtonian potential at both the theoretical and the experimental/observational level. At the theoretical level such deviations are generic predictions in a wide range of extensions of General Relativity (GR) including $f(R)$ theories, massive Brans-Dicke (BD)- scalar tensor theories, compactified extra dimension models and nonlocal extensions of GR. However, the range of parameters associated with such oscillating deviations is usually connected with instabilities present at the perturbative level. An important exception emerges in nonlocal gravity theories where oscillating deviations from Newtonian potential occur naturally on sub-millimeter scales without any instabilities. As an example of a model with unstable Newtonian oscillations we review an $f(R)$ expansion around General Relativity of the form $f(R)=R+\\frac{1}{6 m^2} R^2$ with $m^2<0$ pointing out possible stabilization mechanisms. As an example of a model ...
Barbosa, Marco Aurélio A; de Araújo, Antônio F Pereira
2003-05-01
The relevance of inside-outside segregation and chain compaction for the thermodynamics of folding of a hydrophobic protein model is probed by complete enumeration of two-dimensional chains of up to 18 monomers in the square lattice. The exact computation of Z scores for uniquely designed sequences confirms that Z tends to decrease linearly with sigma square root of N, as previously suggested by theoretical analysis and Monte Carlo simulations, where sigma, the standard deviation of the number of contacts made by different monomers in the target structure, is a measure of structural segregation and N is the chain length. The probability that the target conformation is indeed the unique global energy minimum of the designed sequence is found to increase dramatically with sigma, approaching unity at maximal segregation. However, due to the huge number of conformations with sub-maximal values of sigma, which correspond to intermediate, only mildly discriminative, values of Z, in addition to significant oscillations of Z around its estimated value, the probability that a correctly designed sequence corresponds to a maximally segregated conformation is small. This behavior of Z also explains the observed relation between sigma and different measures of folding cooperativity of correctly designed sequences.
Theoretical and Statistical Models for Predicting Flux in Direct Contact Membrane Distillation
Atia E. Khalifa
2014-06-01
Full Text Available Theoretical modelhas been applied to predict the performance of Direct Contact Membrane Distillation (DCMD based on the analysis of heat and mass transfer through the membrane. The performance of DCMD on the account of different operating parameters had been predicted. Feed inlet temperature, coolant inlet temperature, feed flow rate and coolant flow rate are the considered performance variables. Based on the data obtained from theoretical model, statistical analysis of variance (ANOVA was then performed to determine the significant effect of each operating factors on the DCMD system performance. A new regression model was subsequently developed for predicting the performance of the DCMD system. Resultsrevealed that both theoretical and regression models were in good agreement with each other and also with the selected experimental data used for validation. The maximum percentage error between the two models was found to be1.098%. Hence, the developed regression model is adequate for predict the performance of DCMD system within the domain of the considered analysis.
Impact relevance and usability of high resolution climate modeling and data
Arnott, James C. [Aspen Global Change Inst., Basalt, CO (United States)
2016-10-30
The Aspen Global Change Institute hosted a technical science workshop entitled, “Impact Relevance and Usability of High-Resolution Climate Modeling and Datasets,” on August 2-7, 2015 in Aspen, CO. Kate Calvin (Pacific Northwest National Laboratory), Andrew Jones (Lawrence Berkeley National Laboratory) and Jean-François Lamarque (NCAR) served as co-chairs for the workshop. The meeting included the participation of 29 scientists for a total of 145 participant days. Following the workshop, workshop co-chairs authored a meeting report published in Eos on April 27, 2016. Insights from the workshop directly contributed to the formation of a new DOE-supported project co-led by workshop co-chair Andy Jones. A subset of meeting participants continue to work on a publication on institutional innovations that can support the usability of high resolution modeling, among other sources of climate information.
Sharma, Sakshi; Brahmachari, Goutam; Banerjee, Bubun; Nurjamal, Khondekar; Kumar, Abhishek; Srivastava, Ambrish Kumar; Misra, Neeraj; Pandey, Sarvesh Kumar; Rajnikant; Gupta, Vivek K.
2016-08-01
The present communication deals with the eco-friendly synthesis, spectral properties and X-ray crystal structure of an indole derivative - Ethyl 2'-amino-3'-cyano-6'-methyl-5-nitro-2-oxospiro [indoline-3,4'-pyran]-5'-carboxylate. The title compound was synthesized in 87% yield. The crystal structure of the molecule is stabilized by intermolecular Nsbnd H … N, Nsbnd H … O and Csbnd H … π interactions. The molecule is organized in the crystal lattice forming sheet like structure. To interpret the experimental data, ab initio computations of the vibrational frequencies were carried out using the Gaussian 09 program followed by the full optimizations done using Density Functional Theory (DFT) at B3LYP/6-31 + G(d,p) level. The combined use of experiments and computations allowed a firm assignment of the majority of observed bands for the compound. The calculated highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) with frontier orbital gap were presented. The electronic and charge transfer properties have been explained on the basis of highest occupied molecular orbitals (HOMOs), lowest unoccupied molecular orbitals (LUMOs) and density of states (DOS). From the optimized geometry of the molecule, molecular electrostatic potential (MEP) distribution, frontier molecular orbitals (FMOs) of the title compound have been calculated in the ground state theoretically. The theoretical results showed good agreement with the experimental values. First hyperpolarizability values have been calculated to describe the nonlinear optical (NLO) property of the synthesized compound.
Statistical Models of Fracture Relevant to Nuclear-Grade Graphite: Review and Recommendations
Nemeth, Noel N.; Bratton, Robert L.
2011-01-01
The nuclear-grade (low-impurity) graphite needed for the fuel element and moderator material for next-generation (Gen IV) reactors displays large scatter in strength and a nonlinear stress-strain response from damage accumulation. This response can be characterized as quasi-brittle. In this expanded review, relevant statistical failure models for various brittle and quasi-brittle material systems are discussed with regard to strength distribution, size effect, multiaxial strength, and damage accumulation. This includes descriptions of the Weibull, Batdorf, and Burchell models as well as models that describe the strength response of composite materials, which involves distributed damage. Results from lattice simulations are included for a physics-based description of material breakdown. Consideration is given to the predicted transition between brittle and quasi-brittle damage behavior versus the density of damage (level of disorder) within the material system. The literature indicates that weakest-link-based failure modeling approaches appear to be reasonably robust in that they can be applied to materials that display distributed damage, provided that the level of disorder in the material is not too large. The Weibull distribution is argued to be the most appropriate statistical distribution to model the stochastic-strength response of graphite.
Fragmentation and monomer lengthening of rod-like polymers, a relevant model for prion proliferation
Ciuperca, Ionel Sorin; Palade, Liviu Iulian; Pujo-Menjouet, Laurent
2011-01-01
The Greer, Pujo-Menjouet andWebb model [Greer et al., J. Theoret. Biol., 242 (2006), 598-606] for prion dynamics was found to be in good agreement with experimental observations under no-flow conditions. The objective of this work is to generalize the problem to the framework of general polymerization-fragmentation under flow motion, motivated by the fact that laboratory work often involves prion dynamics under flow conditions in order to observe faster processes. Moreover, understanding and modelling the microstructure influence of macroscopically monitored non-Newtonian behaviour is crucial for sensor design, with the goal to provide practical information about ongoing molecular evolution. This paper's results can then be considered as one step in the mathematical understanding of such models, namely the proof of positivity and existence of solutions in suitable functional spaces. To that purpose, we introduce a new model based on the rigid-rod polymer theory to account for the polymer dynamics under flow c...
Effect of differentiation of self on adolescent risk behavior: test of the theoretical model.
Knauth, Donna G; Skowron, Elizabeth A; Escobar, Melicia
2006-01-01
Innovative theoretical models are needed to explain the occurrence of high-risk sexual behaviors, alcohol and other-drug (AOD) use, and academic engagement among ethnically diverse, inner-city adolescents. The aim of this study was to test the credibility of a theoretical model based on the Bowen family systems theory to explain adolescent risk behavior. Specifically tested was the relationship between the predictor variables of differentiation of self, chronic anxiety, and social problem solving and the dependent variables of high-risk sexual behaviors, AOD use, and academic engagement. An ex post facto cross-sectional design was used to test the usefulness of the theoretical model. Data were collected from 161 racially/ethnically diverse, inner-city high school students, 14 to 19 years of age. Participants completed self-report written questionnaires, including the Differentiation of Self Inventory, State-Trait Anxiety Inventory, Social Problem Solving for Adolescents, Drug Involvement Scale for Adolescents, and the Sexual Behavior Questionnaire. Consistent with the model, higher levels of differentiation of self related to lower levels of chronic anxiety (p relationship between differentiation of self and social problem solving (p < .001), indicating that differentiation influences social problem solving through chronic anxiety. Higher levels of social problem solving were related to less drug use (p < .05), less high-risk sexual behaviors (p < .01), and an increase in academic engagement (p < .01). Findings support the theoretical model's credibility and provide evidence that differentiation of self is an important cognitive factor that enables adolescents to manage chronic anxiety and motivates them to use effective problem solving, resulting in less involvement in health-comprising behaviors and increased academic engagement.
A note on Black-Scholes pricing model for theoretical values of stock options
Edeki, S. O.; Ugbebor, O. O.; Owoloko, E. A.
2016-02-01
In this paper, we consider some conditions that transform the classical Black-Scholes Model for stock options valuation from its partial differential equation (PDE) form to an equivalent ordinary differential equation (ODE) form. In addition, we propose a relatively new semi-analytical method for the solution of the transformed Black-Scholes model. The obtained solutions via this method can be used to find the theoretical values of the stock options in relation to their fair prices. In considering the reliability and efficiency of the models, we test some cases and the results are in good agreement with the exact solution.
AN Zhi-Wu; WANG Xiao-Min; LI Ming-Xuan; DENG Ming-Xi; MAO Jie
2009-01-01
Based on the exact solutions for the second-harmonic generations of the fundamental longitudinal and transverse waves propagating normally through a thin elastic layer between two solids, the approximate representations termed as 'nonlinear spring models' relating the stresses and displacements on both sides of the interface are rigorously developed by asymptotic expansions of the wave fields for an elastic layer in the limit of small thickness to wavelength ratio. The applicability for the so-called nonlinear spring models is numerically analyzed by comparison with exact solutions for the second harmonic wave reflections. The present nonlinear spring models lay a theoretical foundation to evaluate the interracial properties by nonlinear acoustic waves.
From research excellence to brand relevance: A model for higher education reputation building
Nina Overton-de Klerk
2016-05-01
Full Text Available In this article we propose a novel approach to reputation development at higher education institutions. Global reputation development at higher education institutions is largely driven by research excellence, is predominantly measured by research output, and is predominantly reflected in hierarchical university rankings. The ranking becomes equated with brand equity. We argue that the current approach to reputation development in higher education institutions is modernist and linear. This is strangely out-of-kilter with the complexities of a transforming society in flux, the demands of a diversity of stakeholders, and the drive towards transdisciplinarity, laterality, reflexivity and relevance in science. Good research clearly remains an important ingredient of a university's brand value. However, a case can be made for brand relevance, co-created in collaboration with stakeholders, as an alternative and non-linear way of differentiation. This approach is appropriate in light of challenges in strategic science globally as well as trends and shifts in the emerging paradigm of strategic communication. In applying strategic communication principles to current trends and issues in strategic science and the communication thereof, an alternative model for strategic reputation building at higher education institutions is developed.
A proposed theoretical model to explain relative age effects in sport.
Hancock, David J; Adler, Ashley L; Côté, Jean
2013-01-01
Exemplary scientific methods describe concepts and provide theories for further testing. For the field of relative age effects (RAEs) in sport, the scientific method appears to be limited to description. The purpose of this paper is to provide a theoretical model to explain RAEs in sport, which researchers can use to test the effects, as well as to generate new hypotheses and recommendations. Herein, we argue that social agents have the largest influence on RAEs. Specifically, we propose that parents influence RAEs through Matthew effects, coaches influence RAEs through Pygmalion effects and athletes influence RAEs through Galatea effects. Integrating these three theories, we propose a model that explains RAEs through these various social agents. This paper provides a theoretical foundation from which researchers can further understand, explain and eventually use to create policies aimed at limiting the negative effect of relative age in sport.
A theoretical model of turbulent fiber suspension and its application to the channel flow
无
2010-01-01
A theoretical model of turbulent fiber suspension is developed by deriving the equations of Reynolds averaged Navier-Stokes,turbulence kinetic energy and turbulence dissipation rate with the additional term of fibers.In order to close the above equations,the equation of probability distribution function for mean fiber orientation is also derived.The theoretical model is applied to the turbulent channel flow and the corresponding equations are solved numerically.The numerical results are verified by comparisons with the experimental ones.The effects of Reynolds number,fiber concentration and fiber aspect-ratio on the velocity profile,turbulent kinetic energy and turbulent dissipation rate are analyzed.Based on the numerical data,the expression for the velocity profile in the turbulent fiber suspension channel flow,which includes the effect of Reynolds number,fiber concentration and aspect-ratio,is proposed.
Model and Set-Theoretic Aspects of Exotic Smoothness Structures on $\\mathbb{R}^4$
Król, Jerzy
2016-01-01
Model-theoretic aspects of exotic smoothness were studied long ago uncovering unexpected relations to noncommutative spaces and quantum theory. Some of these relations were worked out in detail in later work. An important point in the argumentation was the forcing construction of Cohen but without a direct application to exotic smoothness. In this article we assign the set-theoretic forcing on trees to Casson handles and characterize small exotic smooth $R^4$ from this point of view. Moreover, we show how models in some Grothendieck toposes can help describing such differential structures in dimension 4. These results can be used to obtain the deformation of the algebra of usual complex functions to the noncommutative algebra of operators on a Hilbert space. We also discuss the results in the context of the Epstein-Glaser renormalization in QFT.
Theoretical model and optimal design of silicon micromachined ultrasonic imaging transducers
GE; LiFeng
2007-01-01
A theoretical model and mathematical description for silicon micromachined electrostatic or capacitive ultrasonic imaging transducers have been developed. According to the model the basic performance parameters of such a transducer, such as natural frequencies, eigenfunctions, resonance and anti-resonance frequencies, and the mechanical impedance of the diaphragm can be predicted from the geometry of the transducer and property parameters of materials used. The paper reveals that this type of transducers has two basic operation modes, corresponding to the resonance of a mass-spring oscillator comprised of the diaphragm and the air cushion, and the first-order bending mode of the diaphragm itself respectively, and presents an optimal method for extending the bandwidth by making the two modes coupled, and thereby provides a theoretical basis for the optimal design.
Ultraviolet Properties of Primeval Galaxies Theoretical Models from Stellar Population Synthesis
Buzzoni, A
2002-01-01
The ultraviolet luminosity evolution of star-forming galaxies is explored from the theoretical point of view, especially focusing on the theory of UV energetics in simple and composite stellar populations and its relationship to the star formation rate and other main evolutionary parameters. Galaxy emission below 3000 Angstroms directly correlates with actual star formation, not depending on the total mass of the system. A straightforward calibration is obtained, in this sense, from the theoretical models at 1600, 2000 and 2800 Angstroms, and a full comparison is carried out with IUE data and other balloon-borne observations for local galaxies. The claimed role of late-type systems as prevailing contributors to the cosmic UV background is reinforced by our results; at 2000 Angstroms Im irregulars are found in fact nearly four orders of magnitude brighter than ellipticals, per unit luminous mass. The role of dust absorption in the observation of high-redshift galaxies is assessed, comparing model output and ob...
Bulitta, Jurgen B; Landersdorfer, Cornelia B; Forrest, Alan; Brown, Silvia V; Neely, Michael N; Tsuji, Brian T; Louie, Arnold
2011-12-01
Efficacious therapy is of utmost importance to save lives and prevent bacterial resistance in critically ill patients. This review summarizes pharmacokinetic (PK) and pharmacodynamic (PD) modeling methods to optimize clinical care of critically ill patients in empiric and individualized therapy. While these methods apply to all therapeutic areas, we focus on antibiotics to highlight important applications, as emergence of resistance is a significant problem. Nonparametric and parametric population PK modeling, multiple-model dosage design, Monte Carlo simulations, and Bayesian adaptive feedback control are the methods of choice to optimize therapy. Population PK can estimate between patient variability and account for potentially increased clearances and large volumes of distribution in critically ill patients. Once patient- specific PK data become available, target concentration intervention and adaptive feedback control algorithms can most precisely achieve target goals such as clinical cure of an infection or resistance prevention in stable and unstable patients with rapidly changing PK parameters. Many bacterial resistance mechanisms cause PK/PD targets for resistance prevention to be usually several-fold higher than targets for near-maximal killing. In vitro infection models such as the hollow fiber and one-compartment infection models allow one to study antibiotic-induced bacterial killing and emergence of resistance of mono- and combination therapies over clinically relevant treatment durations. Mechanism-based (and empirical) PK/PD modeling can incorporate effects of the immune system and allow one to design innovative dosage regimens and prospective validation studies. Mechanism-based modeling holds great promise to optimize mono- and combination therapy of anti-infectives and drugs from other therapeutic areas for critically ill patients.
Relevance of the Lin's and Host hydropedological models to predict grape yield and wine quality
Costantini, E. A. C.; Pellegrini, S.; Bucelli, P.; Storchi, P.; Vignozzi, N.; Barbetti, R.; Campagnolo, S.
2009-09-01
The adoption of precision agriculture in viticulture could be greatly enhanced by the diffusion of straightforward and easy to be applied hydropedological models, able to predict the spatial variability of available soil water. The Lin's and Host hydropedological models were applied to standard soil series descriptions and hillslope position, to predict the distribution of hydrological functional units in two vineyard and their relevance for grape yield and wine quality. A three-years trial was carried out in Chianti (Central Italy) on Sangiovese. The soils of the vineyards differentiated in structure, porosity and related hydropedological characteristics, as well as in salinity. Soil spatial variability was deeply affected by earth movement carried out before vine plantation. Six plots were selected in the different hydrological functional units of the two vineyards, that is, at summit, backslope and footslope morphological positions, to monitor soil hydrology, grape production and wine quality. Plot selection was based upon a cluster analysis of local slope, topographic wetness index (TWI), and cumulative moisture up to the root limiting layer, appreciated by means of a detailed combined geophysical survey. Water content, redox processes and temperature were monitored, as well as yield, phenological phases, and chemical analysis of grapes. The isotopic ratio δ13C was measured in the wine ethanol upon harvesting to evaluate the degree of stress suffered by vines. The grapes in each plot were collected for wine making in small barrels. The wines obtained were analysed and submitted to a blind organoleptic testing. The results demonstrated that the combined application of the two hydropedological models can be used for the prevision of the moisture status of soils cultivated with grape during summertime in Mediterranean climate. As correctly foreseen by the models, the amount of mean daily transpirable soil water (TSW) during the growing season differed
Relevance of the Lin's and Host hydropedological models to predict grape yield and wine quality
E. A. C. Costantini
2009-09-01
Full Text Available The adoption of precision agriculture in viticulture could be greatly enhanced by the diffusion of straightforward and easy to be applied hydropedological models, able to predict the spatial variability of available soil water. The Lin's and Host hydropedological models were applied to standard soil series descriptions and hillslope position, to predict the distribution of hydrological functional units in two vineyard and their relevance for grape yield and wine quality. A three-years trial was carried out in Chianti (Central Italy on Sangiovese. The soils of the vineyards differentiated in structure, porosity and related hydropedological characteristics, as well as in salinity. Soil spatial variability was deeply affected by earth movement carried out before vine plantation. Six plots were selected in the different hydrological functional units of the two vineyards, that is, at summit, backslope and footslope morphological positions, to monitor soil hydrology, grape production and wine quality. Plot selection was based upon a cluster analysis of local slope, topographic wetness index (TWI, and cumulative moisture up to the root limiting layer, appreciated by means of a detailed combined geophysical survey. Water content, redox processes and temperature were monitored, as well as yield, phenological phases, and chemical analysis of grapes. The isotopic ratio δ^{13}C was measured in the wine ethanol upon harvesting to evaluate the degree of stress suffered by vines. The grapes in each plot were collected for wine making in small barrels. The wines obtained were analysed and submitted to a blind organoleptic testing.
The results demonstrated that the combined application of the two hydropedological models can be used for the prevision of the moisture status of soils cultivated with grape during summertime in Mediterranean climate. As correctly foreseen by the models, the amount of mean daily transpirable soil water (TSW during
How career variety promotes the adaptability of managers: a theoretical model
Karaevli, Ayşe; Karaevli, Ayse; Hall, Douglas T. Tim
2006-01-01
This paper presents a theoretical model showing how managerial adaptability develops from career variety over the span of the person’s career. By building on the literature of career theory, adult learning and development, and career adjustment, we oVer a new conceptualization of managerial adaptability by identifying its behavioral, cognitive, and socio-emotional dimensions, discuss how these competencies can develop from the variety of managers’ cumulative career experiences, and propose se...
Theoretical Calculation of Rotational Bands of 179Pt in the Particle-Triaxial-Rotor Model
CHEN Guo-Jie; SONG Hui-Chao; LIU Yu-Xin
2005-01-01
Theoretical calculations have been performed for nucleus 179Pt in the particle-triaxial-rotor model with variable moment of inertia. The obtained energy spectrum agrees with the experimental data quite well. The calculated results indicate that the bands 1/2- and 7/2+ are triaxial deformation bands and originate mainly from the v[521]1/2- and v[633]7/2+ configurations respectively.
Control Theoretic Modeling and Generated Flow Patterns of a Fish-Tail Robot
Massey, Brian; Morgansen, Kristi; Dabiri, Dana
2003-11-01
Many real-world engineering problems involve understanding and manipulating fluid flows. One of the challenges to further progress in the area of active flow control is the lack of appropriate models that are amenable to control-theoretic studies and algorithm design and also incorporate reasonably realistic fluid dynamic effects. We focus here on modeling and model-verification of bio-inspired actuators (fish-fin type structures) used to control fluid dynamic artifacts that will affect speed, agility, and stealth of Underwater Autonomous Vehicles (UAVs). Vehicles using fish-tail type systems are more maneuverable, can turn in much shorter and more constrained spaces, have lower drag, are quieter and potentially more efficient than those using propellers. We will present control-theoretic models for a simple prototype coupled fluid and mechanical actuator where fluid effects are crudely modeled by assuming only lift, drag, and added mass, while neglecting boundary effects. These models will be tested with different control input parameters on an experimental fish-tail robot with the resulting flow captured with DPIV. Relations between the model, the control function choices, the obtained thrust and drag, and the corresponding flow patterns will be presented and discussed.
A theoretical approach to room acoustic simulations based on a radiative transfer model
Ruiz-Navarro, Juan-Miguel; Jacobsen, Finn; Escolano, José
2010-01-01
A theoretical approach to room acoustic simulations based on a radiative transfer model is developed by adapting the classical radiative transfer theory from optics to acoustics. The proposed acoustic radiative transfer model expands classical geometrical room acoustic modeling algorithms...... by incorporating a propagation medium that absorbs and scatters radiation, handling both diffuse and non-diffuse reflections on boundaries and objects in the room. The main scope of this model is to provide a proper foundation for a wide number of room acoustic simulation models, in order to establish and unify...... their principles. It is shown that this room acoustic modeling technique establishes the basis of two recently proposed algorithms, the acoustic diffusion equation and the room acoustic rendering equation. Both methods are derived in detail using an analytical approximation and a simplified integral equation...
Petrov, Blagovest; Vink, Jorick S.; Gräfener, Götz
2016-05-01
Luminous blue variables (LBVs) have been suggested to be the direct progenitors of supernova Types IIb and IIn, with enhanced mass loss prior to explosion. However, the mechanism of this mass loss is not yet known. Here, we investigate the qualitative behaviour of theoretical stellar wind mass loss as a function of Teff across two bi-stability jumps in blue supergiant regime and also in proximity to the Eddington limit, relevant for LBVs. To investigate the physical ingredients that play a role in the radiative acceleration we calculate blue supergiant wind models with the CMFGEN non-local thermodynamic equilibrium model atmosphere code over an effective temperature range between 30 000 and 8800 K. Although our aim is not to provide new mass-loss rates for BA supergiants, we study and confirm the existence of two bi-stability jumps in mass-loss rates predicted by Vink et al. However, they are found to occur at somewhat lower Teff (20 000 and 9000 K, respectively) than found previously, which would imply that stars may evolve towards lower Teff before strong mass loss is induced by the bi-stability jumps. When the combined effects of the second bi-stability jump and the proximity to Eddington limit are accounted for, we find a dramatic increase in the mass-loss rate by up to a factor of 30. Further investigation of both bi-stability jumps is expected to lead to a better understanding of discrepancies between empirical modelling and theoretical mass-loss rates reported in the literature, and to provide key inputs for the evolution of both normal AB supergiants and LBVs, as well as their subsequent supernova Type II explosions.
Meta-Theoretical Contributions to the Constitution of a Model-Based Didactics of Science
Ariza, Yefrin; Lorenzano, Pablo; Adúriz-Bravo, Agustín
2016-10-01
There is nowadays consensus in the community of didactics of science (i.e. science education understood as an academic discipline) regarding the need to include the philosophy of science in didactical research, science teacher education, curriculum design, and the practice of science education in all educational levels. Some authors have identified an ever-increasing use of the concept of `theoretical model', stemming from the so-called semantic view of scientific theories. However, it can be recognised that, in didactics of science, there are over-simplified transpositions of the idea of model (and of other meta-theoretical ideas). In this sense, contemporary philosophy of science is often blurred or distorted in the science education literature. In this paper, we address the discussion around some meta-theoretical concepts that are introduced into didactics of science due to their perceived educational value. We argue for the existence of a `semantic family', and we characterise four different versions of semantic views existing within the family. In particular, we seek to contribute to establishing a model-based didactics of science mainly supported in this semantic family.
Theoretical modeling and experimental analysis of solar still integrated with evacuated tubes
Panchal, Hitesh; Awasthi, Anuradha
2016-12-01
In this present research work, theoretical modeling of single slope, single basin solar still integrated with evacuated tubes has been performed based on energy balance equations. Major variables like water temperature, inner glass cover temperature and distillate output has been computed based on theoretical modeling. The experimental setup has been made from locally available materials and installed at Gujarat Power Engineering and Research Institute, Mehsana, Gujarat, India (23.5880°N, 72.3693°E) with 0.04 m depth during 6 months of time interval. From the series of experiments, it is found considerable increment in average distillate output of a solar still when integrated with evacuated tubes not only during daytime but also from night time. In all experimental cases, the correlation of coefficient (r) and root mean square percentage deviation of theoretical modeling and experimental study found good agreement with 0.97 < r < 0.98 and 10.22 < e < 38.4% respectively.
Meta-Theoretical Contributions to the Constitution of a Model-Based Didactics of Science
Ariza, Yefrin; Lorenzano, Pablo; Adúriz-Bravo, Agustín
2016-07-01
There is nowadays consensus in the community of didactics of science (i.e. science education understood as an academic discipline) regarding the need to include the philosophy of science in didactical research, science teacher education, curriculum design, and the practice of science education in all educational levels. Some authors have identified an ever-increasing use of the concept of `theoretical model', stemming from the so-called semantic view of scientific theories. However, it can be recognised that, in didactics of science, there are over-simplified transpositions of the idea of model (and of other meta-theoretical ideas). In this sense, contemporary philosophy of science is often blurred or distorted in the science education literature. In this paper, we address the discussion around some meta-theoretical concepts that are introduced into didactics of science due to their perceived educational value. We argue for the existence of a `semantic family', and we characterise four different versions of semantic views existing within the family. In particular, we seek to contribute to establishing a model-based didactics of science mainly supported in this semantic family.
Prasai, Binay; Wilson, A. R.; Wiley, B. J.; Ren, Y.; Petkov, Valeri
2015-10-01
The extent to which current theoretical modeling alone can reveal real-world metallic nanoparticles (NPs) at the atomic level was scrutinized and demonstrated to be insufficient and how it can be improved by using a pragmatic approach involving straightforward experiments is shown. In particular, 4 to 6 nm in size silica supported Au100-xPdx (x = 30, 46 and 58) explored for catalytic applications is characterized structurally by total scattering experiments including high-energy synchrotron X-ray diffraction (XRD) coupled to atomic pair distribution function (PDF) analysis. Atomic-level models for the NPs are built by molecular dynamics simulations based on the archetypal for current theoretical modeling Sutton-Chen (SC) method. Models are matched against independent experimental data and are demonstrated to be inaccurate unless their theoretical foundation, i.e. the SC method, is supplemented with basic yet crucial information on the length and strength of metal-to-metal bonds and, when necessary, structural disorder in the actual NPs studied. An atomic PDF-based approach for accessing such information and implementing it in theoretical modeling is put forward. For completeness, the approach is concisely demonstrated on 15 nm in size water-dispersed Au particles explored for bio-medical applications and 16 nm in size hexane-dispersed Fe48Pd52 particles explored for magnetic applications as well. It is argued that when ``tuned up'' against experiments relevant to metals and alloys confined to nanoscale dimensions, such as total scattering coupled to atomic PDF analysis, rather than by mere intuition and/or against data for the respective solids, atomic-level theoretical modeling can provide a sound understanding of the synthesis-structure-property relationships in real-world metallic NPs. Ultimately this can help advance nanoscience and technology a step closer to producing metallic NPs by rational design.The extent to which current theoretical modeling alone can
Boscá, A., E-mail: alberto.bosca@upm.es [Instituto de Sistemas Optoelectrónicos y Microtecnología, Universidad Politécnica de Madrid, Madrid 28040 (Spain); Dpto. de Ingeniería Electrónica, E.T.S.I. de Telecomunicación, Universidad Politécnica de Madrid, Madrid 28040 (Spain); Pedrós, J. [Instituto de Sistemas Optoelectrónicos y Microtecnología, Universidad Politécnica de Madrid, Madrid 28040 (Spain); Campus de Excelencia Internacional, Campus Moncloa UCM-UPM, Madrid 28040 (Spain); Martínez, J. [Instituto de Sistemas Optoelectrónicos y Microtecnología, Universidad Politécnica de Madrid, Madrid 28040 (Spain); Dpto. de Ciencia de Materiales, E.T.S.I de Caminos, Canales y Puertos, Universidad Politécnica de Madrid, Madrid 28040 (Spain); Calle, F. [Instituto de Sistemas Optoelectrónicos y Microtecnología, Universidad Politécnica de Madrid, Madrid 28040 (Spain); Dpto. de Ingeniería Electrónica, E.T.S.I. de Telecomunicación, Universidad Politécnica de Madrid, Madrid 28040 (Spain); Campus de Excelencia Internacional, Campus Moncloa UCM-UPM, Madrid 28040 (Spain)
2015-01-28
Due to its intrinsic high mobility, graphene has proved to be a suitable material for high-speed electronics, where graphene field-effect transistor (GFET) has shown excellent properties. In this work, we present a method for extracting relevant electrical parameters from GFET devices using a simple electrical characterization and a model fitting. With experimental data from the device output characteristics, the method allows to calculate parameters such as the mobility, the contact resistance, and the fixed charge. Differentiated electron and hole mobilities and direct connection with intrinsic material properties are some of the key aspects of this method. Moreover, the method output values can be correlated with several issues during key fabrication steps such as the graphene growth and transfer, the lithographic steps, or the metalization processes, providing a flexible tool for quality control in GFET fabrication, as well as a valuable feedback for improving the material-growth process.
The big seven model of personality and its relevance to personality pathology.
Simms, Leonard J
2007-02-01
Proponents of the Big Seven model of personality have suggested that Positive Valence (PV) and Negative Valence (NV) are independent of the Big Five personality dimensions and may be particularly relevant to personality disorder. These hypotheses were tested with 403 undergraduates who completed a Big Seven measure and markers of the Big Five and personality pathology. Results revealed that PV and NV incrementally predicted personality pathology dimensions beyond those predicted by multiple markers of the Big Five. However, factor analyses suggested that PV and NV might be best understood as specific, maladaptive aspects of positive emotionality and low agreeableness, respectively, as opposed to independent factors of personality. Implications for the description of normal and abnormal personality are discussed.
Hense, Inga; Stemmler, Irene; Sonntag, Sebastian
2017-01-01
The current generation of marine biogeochemical modules in Earth system models (ESMs) considers mainly the effect of marine biota on the carbon cycle. We propose to also implement other biologically driven mechanisms in ESMs so that more climate-relevant feedbacks are captured. We classify these mechanisms in three categories according to their functional role in the Earth system: (1) biogeochemical pumps, which affect the carbon cycling; (2) biological gas and particle shuttles, which affect the atmospheric composition; and (3) biogeophysical mechanisms, which affect the thermal, optical, and mechanical properties of the ocean. To resolve mechanisms from all three classes, we find it sufficient to include five functional groups: bulk phyto- and zooplankton, calcifiers, and coastal gas and surface mat producers. We strongly suggest to account for a larger mechanism diversity in ESMs in the future to improve the quality of climate projections.
Marasulov, Akhmat; Saipov, Amangeldi; ?rymbayeva, Kulimkhan; Zhiyentayeva, Begaim; Demeuov, Akhan; Konakbaeva, Ulzhamal; Bekbolatova, Akbota
2016-01-01
The aim of the study is to examine the methodological-theoretical construction bases for development mechanism of an integrated model for a specialist's training and teacher's conceptual-theoretical activity. Using the methods of generalization of teaching experience, pedagogical modeling and forecasting, the authors determine the urgent problems…
Hansson, Lena; Hansson, Örjan; Juter, Kristina; Redfors, Andreas
2015-01-01
This article discusses the role of mathematics during physics lessons in upper-secondary school. Mathematics is an inherent part of theoretical models in physics and makes powerful predictions of natural phenomena possible. Ability to use both theoretical models and mathematics is central in physics. This paper takes as a starting point that the…
Grace, J.B.; Bollen, K.A.
2008-01-01
Structural equation modeling (SEM) holds the promise of providing natural scientists the capacity to evaluate complex multivariate hypotheses about ecological systems. Building on its predecessors, path analysis and factor analysis, SEM allows for the incorporation of both observed and unobserved (latent) variables into theoretically-based probabilistic models. In this paper we discuss the interface between theory and data in SEM and the use of an additional variable type, the composite. In simple terms, composite variables specify the influences of collections of other variables and can be helpful in modeling heterogeneous concepts of the sort commonly of interest to ecologists. While long recognized as a potentially important element of SEM, composite variables have received very limited use, in part because of a lack of theoretical consideration, but also because of difficulties that arise in parameter estimation when using conventional solution procedures. In this paper we present a framework for discussing composites and demonstrate how the use of partially-reduced-form models can help to overcome some of the parameter estimation and evaluation problems associated with models containing composites. Diagnostic procedures for evaluating the most appropriate and effective use of composites are illustrated with an example from the ecological literature. It is argued that an ability to incorporate composite variables into structural equation models may be particularly valuable in the study of natural systems, where concepts are frequently multifaceted and the influence of suites of variables are often of interest. ?? Springer Science+Business Media, LLC 2007.
Software for energy modelling: a theoretical basis for improvements in the user interface
Siu, Y.L.
1989-09-01
A philosophical critique of the relationships between theory, knowledge and practice for a range of existing energy modelling styles is presented. In particular, Habermas's ideas are invoked regarding the three spheres of cognitive interest (i.e. technical, practical and emancipatory) and three levels of understanding of knowledge, the construction of an 'ideal speech situation', and the theory of communicative competence and action. These are adopted as a basis for revealing shortcomings of a representative selection of existing computer-based energy modelling styles, and as a springboard for constructing a new theoretical approach. (author).
Team Resilience as a Second-Order Emergent State: A Theoretical Model and Research Directions
Bowers, Clint; Kreutzer, Christine; Cannon-Bowers, Janis; Lamb, Jerry
2017-01-01
Resilience has been recognized as an important phenomenon for understanding how individuals overcome difficult situations. However, it is not only individuals who face difficulties; it is not uncommon for teams to experience adversity. When they do, they must be able to overcome these challenges without performance decrements.This manuscript represents a theoretical model that might be helpful in conceptualizing this important construct. Specifically, it describes team resilience as a second-order emergent state. We also include research propositions that follow from the model. PMID:28861013
Saunders, James A
2015-03-01
Fundamental Christianity and psychology are frequently viewed as incompatible pursuits. However, proponents of the integrationist movement posit that pastoral counselors can utilize principles from psychology if they adopt the premise that all truth is God's truth. Assuming this perspective, Cognitive-Existential Family Therapy (CEFT) - a theoretical integration model compatible with Christian fundamentalism - is proposed. The philosophical assumptions and models of personality, health, and abnormality are explored. Additionally, the article provides an overview of the therapeutic process. © The Author(s) 2015 Reprints and permissions:sagepub.co.uk/journalsPermissions.nav.
Team Resilience as a Second-Order Emergent State: A Theoretical Model and Research Directions
Clint Bowers
2017-08-01
Full Text Available Resilience has been recognized as an important phenomenon for understanding how individuals overcome difficult situations. However, it is not only individuals who face difficulties; it is not uncommon for teams to experience adversity. When they do, they must be able to overcome these challenges without performance decrements.This manuscript represents a theoretical model that might be helpful in conceptualizing this important construct. Specifically, it describes team resilience as a second-order emergent state. We also include research propositions that follow from the model.
Yang, H -Y K; Ricker, P M
2012-01-01
Cosmological constraints derived from galaxy clusters rely on accurate predictions of cluster observable properties, in which feedback from active galactic nuclei (AGN) is a critical component. In order to model the physical effects due to supermassive black holes (SMBH) on cosmological scales, subgrid modeling is required, and a variety of implementations have been developed in the literature. However, theoretical uncertainties due to model and parameter variations are not yet well understood, limiting the predictive power of simulations including AGN feedback. By performing a detailed parameter sensitivity study in a single cluster using several commonly-adopted AGN accretion and feedback models with FLASH, we quantify the model uncertainties in predictions of cluster integrated properties. We find that quantities that are more sensitive to gas density have larger uncertainties (~20% for Mgas and a factor of ~2 for Lx at R500), whereas Tx, Ysz, and Yx are more robust (~10-20% at R500). To make predictions b...
A theoretical model for ionospheric electric fields at mid- and low-latitudes
YU; Tao(余涛); WAN; Weixing(万卫星); LIU; Libo(刘立波)
2003-01-01
A theoretical model for ionospheric electric fields at mid- and Iow-latitudes is developed.In the geomagnetic dipolar coordinate system, we deduce a partial differential equation of electricpotential from the ionospheric dynamo theory. The deduced equation is taken as the fundamentalequation for the present model. The principal parameters for the model input, the thermosphericneutral winds, the densities and temperatures of electrons, ions and neutral atoms and molecules,are obtained from the empirical models HWM93, IRI90 and MSISE90, respectively. In terms of therelaxation iteration method, the partial equations for electric potential are solved successfully, andthen, the ionospheric electric potential, fields, and currents are derived. Our model can reproducethe main features of the ionospheric electrodynamical processes such as the equatorial electric jet(EEJ), so it will be a useful tool for studying the upper atmosphere and ionosphere.
Prasai, Binay; Wilson, A R; Wiley, B J; Ren, Y; Petkov, Valeri
2015-11-14
The extent to which current theoretical modeling alone can reveal real-world metallic nanoparticles (NPs) at the atomic level was scrutinized and demonstrated to be insufficient and how it can be improved by using a pragmatic approach involving straightforward experiments is shown. In particular, 4 to 6 nm in size silica supported Au(100-x)Pd(x) (x = 30, 46 and 58) explored for catalytic applications is characterized structurally by total scattering experiments including high-energy synchrotron X-ray diffraction (XRD) coupled to atomic pair distribution function (PDF) analysis. Atomic-level models for the NPs are built by molecular dynamics simulations based on the archetypal for current theoretical modeling Sutton-Chen (SC) method. Models are matched against independent experimental data and are demonstrated to be inaccurate unless their theoretical foundation, i.e. the SC method, is supplemented with basic yet crucial information on the length and strength of metal-to-metal bonds and, when necessary, structural disorder in the actual NPs studied. An atomic PDF-based approach for accessing such information and implementing it in theoretical modeling is put forward. For completeness, the approach is concisely demonstrated on 15 nm in size water-dispersed Au particles explored for bio-medical applications and 16 nm in size hexane-dispersed Fe48Pd52 particles explored for magnetic applications as well. It is argued that when "tuned up" against experiments relevant to metals and alloys confined to nanoscale dimensions, such as total scattering coupled to atomic PDF analysis, rather than by mere intuition and/or against data for the respective solids, atomic-level theoretical modeling can provide a sound understanding of the synthesis-structure-property relationships in real-world metallic NPs. Ultimately this can help advance nanoscience and technology a step closer to producing metallic NPs by rational design.
José A. F. O. Correia
2016-01-01
Full Text Available Structural design taking into account fatigue damage requires a thorough knowledge of the behaviour of materials. In addition to the monotonic behaviour of the materials, it is also important to assess their cyclic response and fatigue crack propagation behaviour under constant and variable amplitude loading. Materials whenever subjected to fatigue cracking may exhibit mean stress effects as well as crack closure effects. In this paper, a theoretical model based on the same initial assumptions of the analytical models proposed by Hudak and Davidson and Ellyin is proposed to estimate the influence of the crack closure effects. This proposal based further on Walker’s propagation law was applied to the P355NL1 steel using an inverse analysis (back-extrapolation of experimental fatigue crack propagation results. Based on this proposed model it is possible to estimate the crack opening stress intensity factor, Kop, the relationship between U=ΔKeff/ΔK quantity and the stress intensity factor, the crack length, and the stress ratio. This allows the evaluation of the influence of the crack closure effects for different stress ratio levels, in the fatigue crack propagation rates. Finally, a good agreement is found between the proposed theoretical model and the analytical models presented in the literature.
Dong, Ren G.; Welcome, Daniel E.; McDowell, Thomas W.; Wu, John Z.
2015-01-01
While simulations of the measured biodynamic responses of the whole human body or body segments to vibration are conventionally interpreted as summaries of biodynamic measurements, and the resulting models are considered quantitative, this study looked at these simulations from a different angle: model calibration. The specific aims of this study are to review and clarify the theoretical basis for model calibration, to help formulate the criteria for calibration validation, and to help appropriately select and apply calibration methods. In addition to established vibration theory, a novel theorem of mechanical vibration is also used to enhance the understanding of the mathematical and physical principles of the calibration. Based on this enhanced understanding, a set of criteria was proposed and used to systematically examine the calibration methods. Besides theoretical analyses, a numerical testing method is also used in the examination. This study identified the basic requirements for each calibration method to obtain a unique calibration solution. This study also confirmed that the solution becomes more robust if more than sufficient calibration references are provided. Practically, however, as more references are used, more inconsistencies can arise among the measured data for representing the biodynamic properties. To help account for the relative reliabilities of the references, a baseline weighting scheme is proposed. The analyses suggest that the best choice of calibration method depends on the modeling purpose, the model structure, and the availability and reliability of representative reference data. PMID:26740726
Mutarelli, Rita de Cassia; Lima, Ana Cecilia de Souza; Sabundjian, Gaiane, E-mail: rmutarelli@gmail.com, E-mail: aclima@ipen.br, E-mail: gdjian@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)
2015-07-01
Social responsibility has been one of the great discussions in institutional management, and that is an important variable in the strategy and performance of the institutions. The Instituto de Pesquisas Energeticas e Nucleares (IPEN) has worked for the development of environmental and social issues, converging mainly to the benefit of the population. The theory that guides the social responsibility practices is always difficult to measure for several reasons. One reason for this difficulty is that social responsibility involves a variety of issues that are converted in rights, obligations and expectations of different audiences that could be internal and external to the organization. In addition, the different understanding of the institutions about social and environmental issues is another source of complexity. Based on the study context including: the topic being researched, the chosen institute and the questions resulting from the research, the aim of this paper is to propose a theoretical model to describe and analyze the social responsibility of IPEN. The main contribution of this study is to develop a model that integrates the dimensions of social responsibility. These dimensions - also called constructs - are composed of indexes and indicators that were previously used in various contexts of empirical research, combined with the theoretical and conceptual review of social responsibility. The construction of the proposed theoretical model was based on the research of various methodologies and various indicators for measuring social responsibility. This model was statistically tested, analyzed, adjusted, and the end result is a consistent model to measure the perceived value of social responsibility of IPEN. This work could also be applied to other institutions. Moreover, it may be improved and become a tool that will serve as a thermometer to measure social and environmental issues, and will support decision making in various management processes. (author)
INTRODUCTION: Theoretical Models as Mass Media Practice: Perspectives from the West
2007-01-01
at Reuters Institute in May 2007, from which this collection of papers has been selected. As with the other workshops during the conference, the majority of our panellists were themselves once media practitioners. It is my opinion that this background and inside knowledge of the field in itself can provide......What is journalism? How does it exist and why? How does journalism define itself and in what ways can we make use of looking theoretically at the practice of it? These were the central themes of our workshop; Theoretical Models as Mass Media Practice held at the ‘Minding the Gap’ conference...... an exceptional framework for understanding the workings of mass media while helping the press reflect over these workings too. In a time of change for the journalistic profession, when media convergence is growing; the media is marked by deregulation and fewer journalists are being asked to do more...
Sample correlations of infinite variance time series models: an empirical and theoretical study
Jason Cohen
1998-01-01
Full Text Available When the elements of a stationary ergodic time series have finite variance the sample correlation function converges (with probability 1 to the theoretical correlation function. What happens in the case where the variance is infinite? In certain cases, the sample correlation function converges in probability to a constant, but not always. If within a class of heavy tailed time series the sample correlation functions do not converge to a constant, then more care must be taken in making inferences and in model selection on the basis of sample autocorrelations. We experimented with simulating various heavy tailed stationary sequences in an attempt to understand what causes the sample correlation function to converge or not to converge to a constant. In two new cases, namely the sum of two independent moving averages and a random permutation scheme, we are able to provide theoretical explanations for a random limit of the sample autocorrelation function as the sample grows.
Jun, Xu; Bo, You; Xin, Li; Juan, Cui
2007-12-01
To accurately measure temperatures, a novel temperature sensor based on a quartz tuning fork resonator has been designed. The principle of the quartz tuning fork temperature sensor is that the resonant frequency of the quartz resonator changes with the variation in temperature. This type of tuning fork resonator has been designed with a new doubly rotated cut work at flexural vibration mode as temperature sensor. The characteristics of the temperature sensor were evaluated and the results sufficiently met the target of development for temperature sensor. The theoretical model for temperature sensing has been developed and built. The sensor structure was analysed by finite element method (FEM) and optimized, including tuning fork geometry, tine electrode pattern and the sensor's elements size. The performance curve of output versus measured temperature is given. The results from theoretical analysis and experiments indicate that the sensor's sensitivity can reach 60 ppm °C-1 with the measured temperature range varying from 0 to 100 °C.
Theoretical Calculation Model of Single Rip Tearing Strength for the Nonwoven Composites
QIAN Cheng
2005-01-01
The nonwoven composites have sandwich structure, with the first and third layers being nonwovens and the middle layer of woven fabric. On the basis of tests of the single rip tearing strength and drawing out resistances of both the nonwoven composites and the woven fabric, the single rip tearing failure mechanism of the composites were analyzed.Then theoretical calculation model for the single rip tearing strength was established, which indicates that the breaking strength of warp and weft yarns in the nonwoven composites, the density of warp and weft yarns and drawing out resistances are the main influencing factors. In the end,experimental verification was made, which shows that theoretical values conform to the measured values well.
Designing m-learning for junior registrars--activation of a theoretical model of clinical knowledge.
Kanstrup, Anne Marie; Boye, Niels; Nøhr, Christian
2007-01-01
The MINI-project aims at supporting junior registrars in the learning process of how to utilize their theoretical knowledge from Medical School in everyday clinical reasoning and practice. Due to the nature of the work--concurrent moving, learning and producing--we designed an m-learning application. This paper introduces the possibilities and challenges for design of the m-learning application based on a) analytical findings on learning and mobility as derived from the design case--an emergency medical ward b) theoretical perspectives on medical knowledge, and c) presentation of the design of an m-learning application. The design process was based on user-driven innovation and the paper discusses considerations on how to combine user-drive and generic models.
Theoretical Standard Model Rates of Proton to Neutron Conversions Near Metallic Hydride Surfaces
Widom, A
2006-01-01
The process of radiation induced electron capture by protons or deuterons producing new ultra low momentum neutrons and neutrinos may be theoretically described within the standard field theoretical model of electroweak interactions. For protons or deuterons in the neighborhoods of surfaces of condensed matter metallic hydride cathodes, such conversions are determined in part by the collective plasma modes of the participating charged particles, e.g. electrons and protons. The radiation energy required for such low energy nuclear reactions may be supplied by the applied voltage required to push a strong charged current across a metallic hydride surface employed as a cathode within a chemical cell. The electroweak rates of the resulting ultra low momentum neutron production are computed from these considerations.
Particle model of full-size ITER-relevant negative ion source.
Taccogna, F; Minelli, P; Ippolito, N
2016-02-01
This work represents the first attempt to model the full-size ITER-relevant negative ion source including the expansion, extraction, and part of the acceleration regions keeping the mesh size fine enough to resolve every single aperture. The model consists of a 2.5D particle-in-cell Monte Carlo collision representation of the plane perpendicular to the filter field lines. Magnetic filter and electron deflection field have been included and a negative ion current density of j(H(-)) = 660 A/m(2) from the plasma grid (PG) is used as parameter for the neutral conversion. The driver is not yet included and a fixed ambipolar flux is emitted from the driver exit plane. Results show the strong asymmetry along the PG driven by the electron Hall (E × B and diamagnetic) drift perpendicular to the filter field. Such asymmetry creates an important dis-homogeneity in the electron current extracted from the different apertures. A steady state is not yet reached after 15 μs.
Particle model of full-size ITER-relevant negative ion source
Taccogna, F., E-mail: francesco.taccogna@nanotec.cnr.it; Minelli, P. [CNR-Nanotec, Bari 70126 (Italy); INFN, Bari 70126 (Italy); Ippolito, N. [INFN, Bari 70126 (Italy)
2016-02-15
This work represents the first attempt to model the full-size ITER-relevant negative ion source including the expansion, extraction, and part of the acceleration regions keeping the mesh size fine enough to resolve every single aperture. The model consists of a 2.5D particle-in-cell Monte Carlo collision representation of the plane perpendicular to the filter field lines. Magnetic filter and electron deflection field have been included and a negative ion current density of j{sub H{sup −}} = 660 A/m{sup 2} from the plasma grid (PG) is used as parameter for the neutral conversion. The driver is not yet included and a fixed ambipolar flux is emitted from the driver exit plane. Results show the strong asymmetry along the PG driven by the electron Hall (E × B and diamagnetic) drift perpendicular to the filter field. Such asymmetry creates an important dis-homogeneity in the electron current extracted from the different apertures. A steady state is not yet reached after 15 μs.
Immune Memory and Exhaustion: Clinically Relevant Lessons from the LCMV Model.
Zehn, D; Wherry, E J
2015-01-01
The development of dysfunctional or exhausted T cells is characteristic of immune responses to chronic viral infections and cancer. Exhausted T cells are defined by reduced effector function, sustained upregulation of multiple inhibitory receptors, an altered transcriptional program and perturbations of normal memory development and homeostasis. This review focuses on (a) illustrating milestone discoveries that led to our present understanding of T cell exhaustion, (b) summarizing recent developments in the field, and (c) identifying new challenges for translational research. Exhausted T cells are now recognized as key therapeutic targets in human infections and cancer. Much of our knowledge of the clinically relevant process of exhaustion derives from studies in the mouse model of Lymphocytic choriomeningitis virus (LCMV) infection. Studies using this model have formed the foundation for our understanding of human T cell memory and exhaustion. We will use this example to discuss recent advances in our understanding of T cell exhaustion and illustrate the value of integrated mouse and human studies and will emphasize the benefits of bi-directional mouse-to-human and human-to-mouse research approaches.
Particle model of full-size ITER-relevant negative ion source
Taccogna, F.; Minelli, P.; Ippolito, N.
2016-02-01
This work represents the first attempt to model the full-size ITER-relevant negative ion source including the expansion, extraction, and part of the acceleration regions keeping the mesh size fine enough to resolve every single aperture. The model consists of a 2.5D particle-in-cell Monte Carlo collision representation of the plane perpendicular to the filter field lines. Magnetic filter and electron deflection field have been included and a negative ion current density of jH- = 660 A/m2 from the plasma grid (PG) is used as parameter for the neutral conversion. The driver is not yet included and a fixed ambipolar flux is emitted from the driver exit plane. Results show the strong asymmetry along the PG driven by the electron Hall (E × B and diamagnetic) drift perpendicular to the filter field. Such asymmetry creates an important dis-homogeneity in the electron current extracted from the different apertures. A steady state is not yet reached after 15 μs.
Gefen, Amit
2010-02-01
The extrapolation of biological damage from a biomechanical model requires that a closed-form mathematical damage threshold function (DTF) be included in the model. A DTF typically includes a generic load variable, being the critical load (e.g., pressure, strain, temperature) causing irreversible tissue or cell damage, and a generic time variable, which represents the exposure to the load (e.g., duration, strain rate). Despite the central role that DTFs play in biomechanical studies, there is no coherent literature on how to formulate a DTF, excluding the field of heat-induced damage studies. This technical note describes six mathematical function types (Richards, Boltzmann, Morgan-Mercer-Flodin, Gompertz, Weibull, Bertalanffy) that are suitable for formulating a wide range of DTFs. These functions were adapted from the theory of restricted growth, and were fitted herein to describe biomechanical damage phenomena. Relevant properties of each adapted function type were extracted to allow efficient fitting of its parameters to empirical biomechanical data, and some practical examples are provided.
Cheryl M. McCormick
2017-02-01
Full Text Available Elevations in glucocorticoids that result from environmental stressors can have programming effects on brain structure and function when the exposure occurs during sensitive periods that involve heightened neural development. In recent years, adolescence has gained increasing attention as another sensitive period of development, a period in which pubertal transitions may increase the vulnerability to stressors. There are similarities in physical and behavioural development between humans and rats, and rats have been used effectively as an animal model of adolescence and the unique plasticity of this period of ontogeny. This review focuses on benefits and challenges of rats as a model for translational research on hypothalamic-pituitary-adrenal (HPA function and stressors in adolescence, highlighting important parallels and contrasts between adolescent rats and humans, and we review the main stress procedures that are used in investigating HPA stress responses and their consequences in adolescence in rats. We conclude that a greater focus on timing of puberty as a factor in research in adolescent rats may increase the translational relevance of the findings.
Is tail vein injection a relevant breast cancer lung metastasis model?
Rashid, Omar M.; Nagahashi, Masayuki; Ramachandran, Suburamaniam; Dumur, Catherine I.; Schaum, Julia C.; Yamada, Akimitsu; Aoyagi, Tomoyoshi; Milstien, Sheldon; Spiegel, Sarah
2013-01-01
Background Two most commonly used animal models for studying breast cancer lung metastasis are: lung metastasis after orthotopic implantation of cells into the mammary gland, and lung implantations produced after tail vein (TV) injection of cells. Tail vein injection can produce lung lesions faster, but little has been studied regarding the differences between these tumors, thus, we examined their morphology and gene expression profiles. Methods Syngeneic murine mammary adenocarcinoma, 4T1-luc2 cells, were implanted either subcutaneously (Sq), orthotopically (OS), or injected via TV in Balb/c mice. Genome-wide microarray analyses of cultured 4T1 cells, Sq tumor, OS tumor, lung metastases after OS (LMet), and lung tumors after TV (TVt) were performed 10 days after implantation. Results Bioluminescence analysis demonstrated different morphology of metastases between LMet and TVt, confirmed by histology. Gene expression profile of cells were significantly different from tumors, OS, Sq, TVt or LMet (10,350 probe sets; FDR≤1%; P1.5-fold-change; P<0.01), with no significant difference between TVt and LMet. Conclusions There were significant differences between the gene profiles of cells in culture and OS versus LMet, but there were no differences between LMet versus TVt. Therefore, the lung tumor generated by TVt can be considered genetically similar to those produced after OS, and thus TVt is a relevant model for breast cancer lung metastasis. PMID:23991292
A clinically relevant model of perinatal global ischemic brain damage in rats.
Yang, Ting; Zhuang, Lei; Terrando, Niccolò; Wu, Xinmin; Jonhson, Mark R; Maze, Mervyn; Ma, Daqing
2011-04-06
We have designed a clinically relevant model of perinatal asphyxia providing intrapartum hypoxia in rats. On gestation day 22 SD rats were anesthetized and the uterine horns were exteriorized and placed in a water bath at 37°C for up to 20min. After this, pups were delivered from the uterus and manually stimulated to initiate breathing in an incubator at 37°C for 1 h in air. Brains were harvested and stained with cresyl violet, caspase-3, and TUNEL to detect morphological and apoptotic changes on postnatal days (PND) 1, 3, and 7. Separate cohorts were maintained until PND 50 and tested for learning and memory using Morris water maze (WM). Survival rate was decreased with longer hypoxic time, and 100% mortality was noted when hypoxia time was beyond 18min. Apoptosis was increased with the duration of hypoxia with neuronal loss and cell shrinkage in the CA1 of hippocampus. The time taken for the juveniles to locate the hidden platform during WM was increased in animals subjected to hypoxia. These data demonstrate that perinatal ischemic injury leads to neuronal death in the hippocampus and long-lasting cognitive dysfunction. This model mimics hypoxic ischemic encephalopathy in humans and may be appropriate for investigating therapeutic interventions. Copyright © 2011 Elsevier B.V. All rights reserved.
Utilisation of theoretical models and frameworks in the process of evidence synthesis.
Godfrey, Christina M; Harrison, Margaret B; Graham, Ian D; Ross-White, Amanda
2010-01-01
A systematic review is a comprehensive enquiry or study of secondary data sources. There is a research question, an a priori articulation of methods and a set of procedures to focus the investigation. Despite these rigorous structures to guide the review, synthesising evidence is a challenging, resource intense and time consuming process. Large volumes of information complicate not only the search functions, but also the conceptualisation of the evidence needed to create the concise and integrated results. Use of a theoretical model or framework could serve as an essential element in effectively focusing the review and designing the methods to respond to the knowledge question. This scoping review sought to confirm the value of models or frameworks used by authors working within traditional methodologies for evidence synthesis. Types of participants The focus of this review was on the context of health care.Types of intervention(s)/phenomena of interest All studies that discussed models or frameworks used specifically to address the process of synthesis were included.Types of studies Discussion, scholarship or methodology papers and reviews were included.Types of outcome All theoretical models or frameworks were described, with specific attention to the purpose of the framework for each study, and the contribution of the framework to the process of synthesis. The search strategy aimed to find both published and unpublished studies. A three-step search strategy was utilised. The databases for published material included CINAHL; Medline; EMBASE; PsycINFO; AMED; Cochrane; Biomed Central; Scirus; and Mednar. Databases for unpublished material included Dissertation Abstracts; Sociological Abstracts; Conference proceedings. The review was a focused scoping review to locate and describe the contribution of theoretical models or frameworks to the process of synthesis. The methodological quality of the discussion papers was therefore not assessed. Data was extracted from
R. Du Preez
2003-10-01
Full Text Available This article is based on the conceptual theoretical model developed in Part 1 of this series of articles. The objective of this research is to identify female apparel consumer market segments on the basis of differentiating lifestyles, shopping orientation, cultural consciousness, store patronage and demographics. These profiles are discussed in full and the implications thereof for retailers, marketers and researchers are highlighted. A new conceptual model is proposed and recommendations are made for further research. Opsomming Hierdie artikel word gebaseer op die konseptuele teoretiese model wat reeds in Deel 1 van hierdie artikelreeks ontwikkel is. Die doel van hierdie navorsing is om marksegmente van vroue klere-kopers te identifiseer na aanleiding van hulle lewenstyle, kooporiëntasie, kulturele bewustheid, winkelvoorkeurgedrag en demografie. Hierdie profiele word volledig beskryf en die implikasies van die verskillende profiele vir kleinhandelaars, bemarkers en navorsers word uitgelig. ’n Nuwe konseptuele model word voorgestel en aanbevelings vir verdere navorsing word gemaak.
A theoretical adaptive model of thermal comfort - Adaptive Predicted Mean Vote (aPMV)
Yao, Runming [School of Construction Management and Engineering, The University of Reading (United Kingdom); Faculty of Urban Construction and Environmental Engineering, Chongqing University (China); Li, Baizhan [Key Laboratory of the Three Gorges Reservoir Region' s Eco-Environment (Ministry of Education), Chongqing University (China); Faculty of Urban Construction and Environmental Engineering, Chongqing University (China); Liu, Jing [School of Construction Management and Engineering, The University of Reading (United Kingdom)
2009-10-15
This paper presents in detail a theoretical adaptive model of thermal comfort based on the ''Black Box'' theory, taking into account factors such as culture, climate, social, psychological and behavioural adaptations, which have an impact on the senses used to detect thermal comfort. The model is called the Adaptive Predicted Mean Vote (aPMV) model. The aPMV model explains, by applying the cybernetics concept, the phenomena that the Predicted Mean Vote (PMV) is greater than the Actual Mean Vote (AMV) in free-running buildings, which has been revealed by many researchers in field studies. An Adaptive coefficient ({lambda}) representing the adaptive factors that affect the sense of thermal comfort has been proposed. The empirical coefficients in warm and cool conditions for the Chongqing area in China have been derived by applying the least square method to the monitored onsite environmental data and the thermal comfort survey results. (author)
Theoretical Framework and Model Design for Beautiful Countryside Construction in China
ZHENG Xiang-qun
2015-04-01
Full Text Available In the context of China today, the process of beautiful countryside construction mainly imitates the patterns of‘urbanization’construction. However, this approach leads to the loss of countryside characteristics and the separation of agricultural culture. Therefore, it's urgent to carry out research of the theoretical framework and model design for beautiful countryside construction. In this paper, based on the analysis of the beautiful countryside construction connotation, the basic theory of beautiful countryside construction was summarized in three aspects: rural complex ecosystem model, multi-functionality of rural model and sustainable development evaluation model. The basic idea of the beautiful countryside construction mode was studied. The design method of beautiful countryside construction mode was proposed in three levels: planning, scheming and evaluating. The research results might offer scientific reference for improving the scientific and operational nature of beautiful countryside construction.
Constraints on field theoretical models for variation of the fine structure constant
Steinhardt, Charles L.
2005-02-01
Recent theoretical ideas and observational claims suggest that the fine structure constant α may be variable. We examine a spectrum of models in which α is a function of a scalar field. Specifically, we consider three scenarios: oscillating α, monotonic time variation of α, and time-independent α that is spatially varying. We examine the constraints imposed upon these theories by cosmological observations, particle detector experiments, and “fifth force” experiments. These constraints are very strong on models involving oscillation but cannot compete with bounds from the Oklo subnuclear reactor on models with monotonic timelike variation of α. One particular model with spatial variation is consistent with all current experimental and observational measurements, including those from two seemingly conflicting measurements of the fine structure constant using the many multiplet method on absorption lines.
A thematic analysis of theoretical models for translational science in nursing: mapping the field.
Mitchell, Sandra A; Fisher, Cheryl A; Hastings, Clare E; Silverman, Leanne B; Wallen, Gwenyth R
2010-01-01
The quantity and diversity of conceptual models in translational science may complicate rather than advance the use of theory. This paper offers a comparative thematic analysis of the models available to inform knowledge development, transfer, and utilization. Literature searches identified 47 models for knowledge translation. Four thematic areas emerged: (1) evidence-based practice and knowledge transformation processes, (2) strategic change to promote adoption of new knowledge, (3) knowledge exchange and synthesis for application and inquiry, and (4) designing and interpreting dissemination research. This analysis distinguishes the contributions made by leaders and researchers at each phase in the process of discovery, development, and service delivery. It also informs the selection of models to guide activities in knowledge translation. A flexible theoretical stance is essential to simultaneously develop new knowledge and accelerate the translation of that knowledge into practice behaviors and programs of care that support optimal patient outcomes.
F. T. Ademiluyi
2013-01-01
Full Text Available A mathematical model was developed for predicting the drying kinetics of spherical particles in a rotary dryer. Drying experiments were carried out by drying fermented ground cassava particles in a bench scale rotary dryer at inlet air temperatures of 115–230°C, air velocities of 0.83 m/s–1.55 m/s, feed mass of 50–500 g, drum drive speed of 8 rpm, and feed drive speed of 100 rpm to validate the model. The data obtained from the experiments were used to calculate the experimental moisture ratio which compared well with the theoretical moisture ratio calculated from the newly developed Abowei-Ademiluyi model. The comparisons and correlations of the results indicate that validation and performance of the established model are rather reasonable.
Rolling force prediction for strip casting using theoretical model and artificial intelligence
CAO Guang-ming; LI Cheng-gang; ZHOU Guo-ping; LIU Zhen-yu; WU Di; WANG Guo-dong; LIU Xiang-hua
2010-01-01
Rolling force for strip casting of 1Cr17 ferritic stainless steel was predicted using theoretical model and artificial intelligence.Solution zone was classified into two parts by kiss point position during casting strip.Navier-Stokes equation in fluid mechanics and stream function were introduced to analyze the rheological property of liquid zone and mushy zone,and deduce the analytic equation of unit compression stress distribution.The traditional hot rolling model was still used in the solid zone.Neural networks based on feedforward training algorithm in Bayesian regularization were introduced to build model for kiss point position.The results show that calculation accuracy for verification data of 94.67% is in the range of+7.0%,which indicates that the predicting accuracy of this model is very high.
Schuwirth, Nele; Reichert, Peter
2013-02-01
For the first time, we combine concepts of theoretical food web modeling, the metabolic theory of ecology, and ecological stoichiometry with the use of functional trait databases to predict the coexistence of invertebrate taxa in streams. We developed a mechanistic model that describes growth, death, and respiration of different taxa dependent on various environmental influence factors to estimate survival or extinction. Parameter and input uncertainty is propagated to model results. Such a model is needed to test our current quantitative understanding of ecosystem structure and function and to predict effects of anthropogenic impacts and restoration efforts. The model was tested using macroinvertebrate monitoring data from a catchment of the Swiss Plateau. Even without fitting model parameters, the model is able to represent key patterns of the coexistence structure of invertebrates at sites varying in external conditions (litter input, shading, water quality). This confirms the suitability of the model concept. More comprehensive testing and resulting model adaptations will further increase the predictive accuracy of the model.
Ng, Maggie; Mok, Daniel K W; Lee, Edmond P F; Dyke, John M
2015-03-21
The reaction between atomic chlorine (Cl) and methyl nitrate (CH3ONO2) is significant in the atmosphere, as Cl is a key oxidant, especially in the marine boundary layer, and alkyl nitrates are important nitrogen-containing organic compounds, which are temporary reservoirs of the reactive nitrogen oxides NO, NO2 and NO3 (NOx). Four reaction channels HCl + CH2ONO2, CH3OCl + NO2, CH3Cl + NO3 and CH3O + ClNO2 were considered. The major channel is found to be the H abstraction channel, to give the products HCl + CH2ONO2. For all channels, geometry optimization and frequency calculations were carried out at the M06-2X/6-31+G** level, while relative electronic energies were improved to the UCCSD(T*)-F12/CBS level. The reaction barrier (ΔE(‡)0K) and reaction enthalpy (ΔH(RX)298K) of the H abstraction channel were computed to be 0.61 and -2.30 kcal mol(-1), respectively, at the UCCSD(T*)-F12/CBS//M06-2X/6-31+G** level. Reaction barriers (ΔE(‡)0K) for the other channels are more positive and these pathways do not contribute to the overall reaction rate coefficient in the temperature range considered (200-400 K). Rate coefficients were calculated for the H-abstraction channel at various levels of variational transition state theory (VTST) including tunnelling. Recommended ICVT/SCT rate coefficients in the temperature range 200-400 K are presented for the first time for this reaction. The values obtained in the 200-300 K region are particularly important as they will be valuable for atmospheric modelling calculations involving reactions with methyl nitrate. The implications of the results to atmospheric chemistry are discussed. Also, the enthalpies of formation, ΔHf,298K, of CH3ONO2 and CH2ONO2 were computed to be -29.7 and 19.3 kcal mol(-1), respectively, at the UCCSD(T*)-F12/CBS level.
Theoretical Hill-Type Muscle and Stability: Numerical Model and Application
S. Schmitt
2013-01-01
Full Text Available The construction of artificial muscles is one of the most challenging developments in today’s biomedical science. The application of artificial muscles is focused both on the construction of orthotics and prosthetics for rehabilitation and prevention purposes and on building humanoid walking machines for robotics research. Research in biomechanics tries to explain the functioning and design of real biological muscles and therefore lays the fundament for the development of functional artificial muscles. Recently, the hyperbolic Hill-type force-velocity relation was derived from simple mechanical components. In this contribution, this theoretical yet biomechanical model is transferred to a numerical model and applied for presenting a proof-of-concept of a functional artificial muscle. Additionally, this validated theoretical model is used to determine force-velocity relations of different animal species that are based on the literature data from biological experiments. Moreover, it is shown that an antagonistic muscle actuator can help in stabilising a single inverted pendulum model in favour of a control approach using a linear torque generator.
Prediction of the amount of urban waste solids by applying a gray theoretical model
无
2003-01-01
Urban waste solids are now becoming one of the most crucial environmental problems. There are several different kinds of technologies normally used for waste solids disposal, among which landfill is more favorable in China than others, especially for urban waste solids. Most of the design works up to now are based on a roughly estimation of the amount of urban waste solids without any theoretical support, which lead to a series problems. To meet the basic information requirements for the design work, the amount of the urban waste solids was predicted in this research by applying the gray theoretical model GM (1,1) through non-linear differential equation simulation. The model parameters were estimated with the least square method (LSM) by running a certain MATALAB program, and the hypothesis test results show that the residual between the prediction value and the actual value approximately comply with the normal distribution , and the probability of the residual within the range (-0.17, 0.19) is more than 95%, which indicate obviously that the model can be well used for the prediction of the amount of waste solids and those had been already testified by the latest two years data about the urban waste solids from Loudi City of China. With this model, the predicted amount of the waste solids produced in Loudi City in the next 30 years is 8049000 ton in total.
A P-value model for theoretical power analysis and its applications in multiple testing procedures
Fengqing Zhang
2016-10-01
Full Text Available Abstract Background Power analysis is a critical aspect of the design of experiments to detect an effect of a given size. When multiple hypotheses are tested simultaneously, multiplicity adjustments to p-values should be taken into account in power analysis. There are a limited number of studies on power analysis in multiple testing procedures. For some methods, the theoretical analysis is difficult and extensive numerical simulations are often needed, while other methods oversimplify the information under the alternative hypothesis. To this end, this paper aims to develop a new statistical model for power analysis in multiple testing procedures. Methods We propose a step-function-based p-value model under the alternative hypothesis, which is simple enough to perform power analysis without simulations, but not too simple to lose the information from the alternative hypothesis. The first step is to transform distributions of different test statistics (e.g., t, chi-square or F to distributions of corresponding p-values. We then use a step function to approximate each of the p-value’s distributions by matching the mean and variance. Lastly, the step-function-based p-value model can be used for theoretical power analysis. Results The proposed model is applied to problems in multiple testing procedures. We first show how the most powerful critical constants can be chosen using the step-function-based p-value model. Our model is then applied to the field of multiple testing procedures to explain the assumption of monotonicity of the critical constants. Lastly, we apply our model to a behavioral weight loss and maintenance study to select the optimal critical constants. Conclusions The proposed model is easy to implement and preserves the information from the alternative hypothesis.
Petrov, Blagovest; Gräfener, Götz
2016-01-01
Luminous Blue Variables have been suggested to be the direct progenitors of supernova types IIb and IIn, with enhanced mass loss prior to explosion. However, the mechanism of this mass loss is not yet known. Here, we investigate the qualitative behaviour of theoretical stellar wind mass-loss as a function of Teff across two bi-stability jumps in blue supergiant regime and also in proximity to the Eddington limit, relevant for LBVs. To investigate the physical ingredients that play a role in the radiative acceleration we calculate blue supergiant wind models with the CMFGEN non-LTE model atmosphere code over an effective temperature range between 30000 and 8800 K. Although our aim is not to provide new mass-loss rates for BA supergiants, we study and confirm the existence of two bi-stability jumps in mass-loss rates predicted by Vink, de Koter, & Lamers (1999). However, they are found to occur at somewhat lower Teff (20000 and 9000 K, respectively) than found previously, which would imply that stars may ev...
Irina IOSUB
2016-06-01
Full Text Available In the context of increasingly accelerated development of technology and particularly of the Internet, mass communication acquires new meanings. This article proposes a brief theoretical approach to the study of mass communication as it was treated in the specific literature of the 50s and 60s, when there was little talk about new technologies. However, many features identified since then still retain their topicality and for this reason it is interesting to note the evolution over time of the main communication models that were and some of them still are used for the study of mass communication. They are relevant to the context in which a complete study of mass communication is required, not only from the perspective of the present, but also from the period in which it was outlined. Thus, this article is divided into three main sections: the first part represents the meaning of communication in a general sense, so that the second part to represent the mass communication process and its characteristics, and the last part to represent the main models of communication in the order in which they have occurred, and especially aiming at new features that each of them brought.
Staub, Isabelle; Fredriksson, Anders; Outters, Nils [Golder Associates AB, Uppsala (Sweden)
2002-05-01
In the purpose of studying the possibilities of a Deep Repository for spent fuel, the Swedish Nuclear and Fuel Management Company (SKB) is currently planning for Site Investigations. Data collected from these Site Investigations are interpreted and analysed to achieve the full Site Description, which is built up of models from all the disciplines that are considered of importance for the Site Description. One of these models is the Rock Mechanical Descriptive Model,which would be developed for any site in hard crystalline rock, and is a combination and evaluation of the characterisation of rock mass by means of empirical relationships and a theoretical approach based on numerical modelling. The present report describes the theoretical approach. The characterisation of the mechanical properties of the rock mass, viewed as a unit consisting of intact rock and fractures, is achieved by numerical simulations with following input parameters: initial stresses, fracture geometry, distribution of rock mechanical properties, such as deformation and strength parameters, for the intact rock and for the fractures. The numerical modelling was performed with the two-dimensional code UDEC, and the rock block models were generated from 2D trace sections extracted from the 3D Discrete Fracture Network (DFN) model. Assumptions and uncertainties related to the set-up of the model are considered. The numerical model was set-up to simulate a plain strain-loading test. Different boundary conditions were applied on the model for simulating stress conditions (I) in the undisturbed rock mass, and (II) at the proximity of a tunnel. In order to assess the reliability of the model sensitivity analyses have been conducted on some rock block models for defining the dependency of mechanical properties to in situ stresses, the influence of boundary conditions, rock material and joint constitutive models used to simulate the behaviour of intact rock and fractures, domain size and anisotropy. To
Meyer, Jerrold S; Hamel, Amanda F
2014-01-01
Stressful life events have been linked to the onset of severe psychopathology and endocrine dysfunction in many patients. Moreover, vulnerability to the later development of such disorders can be increased by stress or adversity during development (e.g., childhood neglect, abuse, or trauma). This review discusses the methodological features and results of various models of stress in nonhuman primates in the context of their potential relevance for human psychopathology and endocrine dysfunction, particularly mood disorders and dysregulation of the hypothalamic-pituitary-adrenocortical (HPA) system. Such models have typically examined the effects of stress on the animals' behavior, endocrine function (primarily the HPA and hypothalamic-pituitary-gonadal systems), and, in some cases, immune status. Manipulations such as relocation and/or removal of an animal from its current social group or, alternatively, formation of a new social group can have adverse effects on all of these outcome measures that may be either transient or more persistent depending on the species, sex, and other experimental conditions. Social primates may also experience significant stress associated with their rank in the group's dominance hierarchy. Finally, stress during prenatal development or during the early postnatal period may have long-lasting neurobiological and endocrine effects that manifest in an altered ability to cope behaviorally and physiologically with later challenges. Whereas early exposure to severe stress usually results in deficient coping abilities, certain kinds of milder stressors can promote subsequent resilience in the animal. We conclude that studies of stress in nonhuman primates can model many features of stress exposure in human populations and that such studies can play a valuable role in helping to elucidate the mechanisms underlying the role of stress in human psychopathology and endocrine dysfunction.
Khalilian, Morteza; Navidbakhsh, Mahdi; Valojerdi, Mojtaba Rezazadeh; Chizari, Mahmoud; Yazdi, Poopak Eftekhari
2010-04-06
The zona pellucida (ZP) is the spherical layer that surrounds the mammalian oocyte. The physical hardness of this layer plays a crucial role in fertilization and is largely unknown because of the lack of appropriate measuring and modelling methods. The aim of this study is to measure the biomechanical properties of the ZP of human/mouse ovum and to test the hypothesis that Young's modulus of the ZP varies with fertilization. Young's moduli of ZP are determined before and after fertilization by using the micropipette aspiration technique, coupled with theoretical models of the oocyte as an elastic incompressible half-space (half-space model), an elastic compressible bilayer (layered model) or an elastic compressible shell (shell model). Comparison of the models shows that incorporation of the layered geometry of the ovum and the compressibility of the ZP in the layered and shell models may provide a means of more accurately characterizing ZP elasticity. Evaluation of results shows that although the results of the models are different, all confirm that the hardening of ZP will increase following fertilization. As can be seen, different choices of models and experimental parameters can affect the interpretation of experimental data and lead to differing mechanical properties.
The coupled effects of carbon and nitrogen on soil decomposition: A theoretical model
Darby, B.; Finzi, A.
2013-12-01
Soil organic matter (SOM) plays a crucial role in the carbon (C) cycle, holding 2.5 times more carbon than plant biomass. Ecosystem models predict that climate warming will stimulate decomposition of soil carbon stocks, in turn leading to positive feedbacks on warming. Recent empirical studies and modeling work has revealed the importance of microbial physiology and exoenzyme kinetics in driving SOM decomposition. Existing mathematical models describe the microbial processes and biophysics involved in the decomposition. However, although decomposition by nitrogen-degrading enzymes is included in some models, nitrogen (N) does not drive model behavior and there are no reaction kinetics associated with the depolymerization or uptake of N. Additionally, very few empirically measured kinetic values exist for N-degrading enzymes or the uptake of N by microbes. This study proposes a theoretical model of SOM decomposition based on the principles of exoenzyme kinetics and microbial biophysics that explicitly links C and N through microbial uptake and SOM decomposition kinetics and by placing stoichiometric constraints on microbial growth and exoenzyme production. After constructing the model framework, the model was then used to test soil-carbon responses to warming, and to explore the importance of N uptake and depolymerization kinetics in driving decomposition. The model predictions suggest that the response of kinetics to temperature are more important than microbial responses in determining decomposition rates. Additionally, variations in the kinetics of N depolymerization affected decomposition rates, whereas N uptake kinetics and their effect on enzyme production had almost no effect. The model outputs were also compared to a C-only model framework in order to assess the effects of N on model behavior. The incorporation of N into a SOM decomposition model produced different, and in some cases, contradictory results as compared to a C-only model. Overall, these
Ursino, Mauro; Cuppini, Cristiano; Magosso, Elisa
2017-03-01
Recent theoretical and experimental studies suggest that in multisensory conditions, the brain performs a near-optimal Bayesian estimate of external events, giving more weight to the more reliable stimuli. However, the neural mechanisms responsible for this behavior, and its progressive maturation in a multisensory environment, are still insufficiently understood. The aim of this letter is to analyze this problem with a neural network model of audiovisual integration, based on probabilistic population coding-the idea that a population of neurons can encode probability functions to perform Bayesian inference. The model consists of two chains of unisensory neurons (auditory and visual) topologically organized. They receive the corresponding input through a plastic receptive field and reciprocally exchange plastic cross-modal synapses, which encode the spatial co-occurrence of visual-auditory inputs. A third chain of multisensory neurons performs a simple sum of auditory and visual excitations. The work includes a theoretical part and a computer simulation study. We show how a simple rule for synapse learning (consisting of Hebbian reinforcement and a decay term) can be used during training to shrink the receptive fields and encode the unisensory likelihood functions. Hence, after training, each unisensory area realizes a maximum likelihood estimate of stimulus position (auditory or visual). In cross-modal conditions, the same learning rule can encode information on prior probability into the cross-modal synapses. Computer simulations confirm the theoretical results and show that the proposed network can realize a maximum likelihood estimate of auditory (or visual) positions in unimodal conditions and a Bayesian estimate, with moderate deviations from optimality, in cross-modal conditions. Furthermore, the model explains the ventriloquism illusion and, looking at the activity in the multimodal neurons, explains the automatic reweighting of auditory and visual inputs