The endosymbiotic bacterium Wolbachia induces resistance to dengue virus in Aedes aegypti.

Directory of Open Access Journals (Sweden)

Guowu Bian

2010-04-01

Full Text Available Genetic strategies that reduce or block pathogen transmission by mosquitoes have been proposed as a means of augmenting current control measures to reduce the growing burden of vector-borne diseases. The endosymbiotic bacterium Wolbachia has long been promoted as a potential vehicle for introducing disease-resistance genes into mosquitoes, thereby making them refractory to the human pathogens they transmit. Given the large overlap in tissue distribution and intracellular localization between Wolbachia and dengue virus in mosquitoes, we conducted experiments to characterize their interactions. Our results show that Wolbachia inhibits viral replication and dissemination in the main dengue vector, Aedes aegypti. Moreover, the virus transmission potential of Wolbachia-infected Ae. aegypti was significantly diminished when compared to wild-type mosquitoes that did not harbor Wolbachia. At 14 days post-infection, Wolbachia completely blocked dengue transmission in at least 37.5% of Ae. aegypti mosquitoes. We also observed that this Wolbachia-mediated viral interference was associated with an elevated basal immunity and increased longevity in the mosquitoes. These results underscore the potential usefulness of Wolbachia-based control strategies for population replacement.

The Public Sector and Obligation to Contract

DEFF Research Database (Denmark)

Olesen, Karsten Naundrup; Indén, Tobias

2016-01-01

The paper concerns the situation where public sector bodies are forced to enter into contracts. These obligations to contract are analysed from two angles. First, the paper offers an analysis of the reasons for imposing such obligations to contract under Swedish and Danish law. Secondly the paper...... discusses some consequences of the public entities’ obligations to contract, more specific consequences for the use of rules that usually regulate contracts and the fact that obligations to contract imposed on public entities establish a new market and at the same time the obligations deprive the entities...... of the freedom to contract which is a fundamental to market behaviour. Finally attention is drawn to the fact that obligations to contract are also imposed on private entities. The paper takes Swedish and Danish regulations as a point of departure and provides an insight into regulations from these two countries...

Eye-like ocelloids are built from different endosymbiotically acquired components

KAUST Repository

Gavelis, Gregory S.; Hayakawa, Shiho; White, Richard A.; Gojobori, Takashi; Suttle, Curtis A.; Keeling, Patrick J.; Leander, Brian S.

2015-01-01

Multicellularity is often considered a prerequisite for morphological complexity, as seen in the camera-type eyes found in several groups of animals. A notable exception exists in single-celled eukaryotes called dinoflagellates, some of which have an eye-like 'ocelloid' consisting of subcellular analogues to a cornea, lens, iris, and retina. These planktonic cells are uncultivated and rarely encountered in environmental samples, obscuring the function and evolutionary origin of the ocelloid. Here we show, using a combination of electron microscopy, tomography, isolated-organelle genomics, and single-cell genomics, that ocelloids are built from pre-existing organelles, including a cornea-like layer made of mitochondria and a retinal body made of anastomosing plastids. We find that the retinal body forms the central core of a network of peridinin-type plastids, which in dinoflagellates and their relatives originated through an ancient endosymbiosis with a red alga. As such, the ocelloid is a chimaeric structure, incorporating organelles with different endosymbiotic histories. The anatomical complexity of single-celled organisms may be limited by the components available for differentiation, but the ocelloid shows that pre-existing organelles can be assembled into a structure so complex that it was initially mistaken for a multicellular eye. Although mitochondria and plastids are acknowledged chiefly for their metabolic roles, they can also be building blocks for greater structural complexity.

Eye-like ocelloids are built from different endosymbiotically acquired components

KAUST Repository

Gavelis, Gregory S.

2015-07-01

Multicellularity is often considered a prerequisite for morphological complexity, as seen in the camera-type eyes found in several groups of animals. A notable exception exists in single-celled eukaryotes called dinoflagellates, some of which have an eye-like \\'ocelloid\\' consisting of subcellular analogues to a cornea, lens, iris, and retina. These planktonic cells are uncultivated and rarely encountered in environmental samples, obscuring the function and evolutionary origin of the ocelloid. Here we show, using a combination of electron microscopy, tomography, isolated-organelle genomics, and single-cell genomics, that ocelloids are built from pre-existing organelles, including a cornea-like layer made of mitochondria and a retinal body made of anastomosing plastids. We find that the retinal body forms the central core of a network of peridinin-type plastids, which in dinoflagellates and their relatives originated through an ancient endosymbiosis with a red alga. As such, the ocelloid is a chimaeric structure, incorporating organelles with different endosymbiotic histories. The anatomical complexity of single-celled organisms may be limited by the components available for differentiation, but the ocelloid shows that pre-existing organelles can be assembled into a structure so complex that it was initially mistaken for a multicellular eye. Although mitochondria and plastids are acknowledged chiefly for their metabolic roles, they can also be building blocks for greater structural complexity.

29 CFR 500.100 - Vehicle safety obligations.

Science.gov (United States)

2010-07-01

... safety standards. Prima facie evidence that safety standards have been met will be shown by the presence... 29 Labor 3 2010-07-01 2010-07-01 false Vehicle safety obligations. 500.100 Section 500.100 Labor... § 500.100 Vehicle safety obligations. (a) General obligations. Each farm labor contractor, agricultural...

7 CFR 1724.71 - Borrower contractual obligations.

Science.gov (United States)

2010-01-01

... 7 Agriculture 11 2010-01-01 2010-01-01 false Borrower contractual obligations. 1724.71 Section... Contract Forms § 1724.71 Borrower contractual obligations. (a) Loan agreement. As a condition of a loan or... obligation is contained in section 5.16 of the loan contract. To comply with the provisions of the loan...

7 CFR 1726.301 - Borrower contractual obligations.

Science.gov (United States)

2010-01-01

... 7 Agriculture 11 2010-01-01 2010-01-01 false Borrower contractual obligations. 1726.301 Section... Borrower contractual obligations. (a) Loan agreement. As a condition of a loan or loan guarantee under the... obligation is contained in section 5.16 of the loan contract. To comply with the provisions of the loan...

Cancer Moonshot Funding Obligations FY 2017

Science.gov (United States)

NCI reports Cancer Moonshot obligations by funding mechanism. See obligations for Moonshot grants, intramural research, and contracts, including the number of grant awards, funding amounts, and percentages by mechanism of the total Cancer Moonshot budget.

7 CFR 400.167 - Limitations on Corporation's obligations.

Science.gov (United States)

2010-01-01

... 7 Agriculture 6 2010-01-01 2010-01-01 false Limitations on Corporation's obligations. 400.167... INSURANCE CORPORATION, DEPARTMENT OF AGRICULTURE GENERAL ADMINISTRATIVE REGULATIONS Reinsurance Agreement... Corporation's obligations. The Agreement will include the following among the limitations on the obligations...

On the obligation to obey the law

Directory of Open Access Journals (Sweden)

Zekavica Radomir G.

2016-01-01

Full Text Available The paper considers the question of a general obligation to obey the law. The author presents and analyzes the most significant views and arguments in support of the thesis that there is a general obligation to obey the law, as well as those understandings which are refuse this thesis. In concluding remarks the author presents a critical review of some key issues about general obligation to obey the law. In addition, the author outlines a hypothetical model of society and the legal system under which such an obligation is possible and has also asserted the basic assumptions and principles upon which it can be justified and reasonable. .

12 CFR 208.101 - Obligations concerning institutional customers.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Obligations concerning institutional customers...) Interpretations § 208.101 Obligations concerning institutional customers. (a) As a result of broadened authority... on their suitability obligations when making recommendations to institutional customers. (b) The...

NCI & Division Obligations

Science.gov (United States)

Displays obligations for grants, contracts, training fellowships, intramural research, and management and support, including the number of grant awards, funding amounts, and percent of the total NCI budget.

The economics of a landing obligation

DEFF Research Database (Denmark)

Andersen, Peder; Ståhl, Lisa

By 2015 The European Common Fisheries Policy Reform includes a landing obligation in some fisheries and over the next few years all EU fisheries will be facing the obligation to land all catches. In spite of that, there is a lack of theoretical as well as empirical analyses of the consequences...... of a landing obligation. The paper includes an empirical analysis of the landing obligation’s impact on the Danish fishery in the short run. In the first part of the paper, we survey the fisheries economics literature for theoretical findings regarding behavioural aspects of a discard ban and we exploring gaps...... things, the analysis shows that the fisheries will suffer economic losses under the landing obligation if quotas are not increased with the historical discard rate. With quota top-ups however fisheries can experience economic gains which increase with reduced minimum sizes or by increasing selectivity....

47 CFR 27.1168 - Triggering a Reimbursement Obligation.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Triggering a Reimbursement Obligation. 27.1168... a Reimbursement Obligation. (a) The clearinghouse will apply the following test to determine when an... reimbursement obligation exists, the clearinghouse will calculate the reimbursement amount in accordance with...

47 CFR 24.247 - Triggering a reimbursement obligation.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Triggering a reimbursement obligation. 24.247... Mhz Band § 24.247 Triggering a reimbursement obligation. (a) Licensed PCS. The clearinghouse will... the Proximity Threshold test indicates that a reimbursement obligation exists, the clearinghouse will...

45 CFR 2400.65 - Teaching obligation.

Science.gov (United States)

2010-10-01

... FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Special Conditions § 2400.65 Teaching obligation. Upon receiving a Master's degree, each Fellow must teach American history, American government, social studies, or... 45 Public Welfare 4 2010-10-01 2010-10-01 false Teaching obligation. 2400.65 Section 2400.65...

Where to place the saving obligation: Energy end-users or suppliers?

International Nuclear Information System (INIS)

Bertoldi, Paolo; Labanca, Nicola; Rezessy, Silvia; Steuwer, Sibyl; Oikonomou, Vlasis

2013-01-01

Obligations to save energy differentiate, among other features, by obliged parties. These are obligations on energy suppliers and energy end-users. Supplier obligations have been introduced in North America, Europe and Australia. Under supplier obligations energy suppliers have to comply with mandatory energy saving targets and thus they implement (directly or via third parties) energy efficiency projects on their clients’ premises, or they decide to trade certified project savings if this option is envisaged by their obligation scheme. In several emerging schemes such as the UK Carbon Reduction Commitment (CRC) Energy Efficiency Scheme, the Tokyo Emission Trading Scheme or the Perform Achieve and Trade (PAT) Scheme in India, the obligation to reduce energy consumption is placed on large end-users directly and end-users are allowed to trade emissions allowances or energy saving certificates. The paper starts with presenting these two conceptually different ways for introducing energy saving obligations. Then it analyses advantages and disadvantages of end-users obligations compared to suppliers obligations. The preliminary conclusion of the paper is that supplier obligations seem to be well-suited for the residential sector, but end-user saving obligations may offer advantages when it comes to the industrial and commercial sectors. - Highlights: • We present different ways for introducing energy saving obligations. • We analyse energy end-users obligations vs. supplier obligations. • Supplier obligations seem to be well-suited for the residential sector. • End-user obligations offer advantages in the industrial and commercial sectors

Obligation target for sustainable energy

International Nuclear Information System (INIS)

Lensink, S.M.; Hekkenberg, M.

2012-01-01

The Dutch Ministry of Economic Affairs, Agriculture and Innovation asked ECN several questions about the development of a supplier's obligation. These questions addressed the volume of the certificates market. The questions are worded as follows by ECN: What is a realistic level to be set for the obligation for sustainable energy or for renewable electricity (in percentage of delivered electricity or TWh/year)? How far into the future should these obligations minimally be set? Is it desirable to limit the certificate issuance time to for example the economic life of an installation? This memo addresses the questions, knowing that the entire policy development process will still take considerable time. At the time of publication of this memo, large uncertainties still existed about the eventual shaping of future policy. [nl

47 CFR 27.1184 - Triggering a reimbursement obligation.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Triggering a reimbursement obligation. 27.1184... reimbursement obligation. (a) The clearinghouse will apply the following test to determine when an AWS entity... paragraphs (a)(3)(i) and (ii) of this section, indicates that a reimbursement obligation exists, the...

24 CFR 891.755 - Obligations of the family.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Obligations of the family. 891.755... the Elderly and Persons with Disabilities Section 202 Projects for the Nonelderly Handicapped Families and Individuals-Section 162 Assistance § 891.755 Obligations of the family. The obligations of the...

Constitutional obligations of a person and a citizen

Directory of Open Access Journals (Sweden)

Alexey Yu. Ogurtsov

2011-01-01

Full Text Available The constitution of the Russian Federation does not contain the list of obligations, but theoretically each legal right is supposed to correspond to a legal obligation. Such conformity is achieved by means of attaching obligations not only by Constitution, but by the branch legislation either.

12 CFR 997.5 - Termination of the obligation.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Termination of the obligation. 997.5 Section 997.5 Banks and Banking FEDERAL HOUSING FINANCE BOARD NON-BANK SYSTEM ENTITIES RESOLUTION FUNDING CORPORATION OBLIGATIONS OF THE BANKS § 997.5 Termination of the obligation. (a) Generally. The Banks...

24 CFR 891.615 - Obligations of the family.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Obligations of the family. 891.615 Section 891.615 Housing and Urban Development Regulations Relating to Housing and Urban Development... 8 Assistance § 891.615 Obligations of the family. The obligations of the family are provided in...

47 CFR 27.1239 - Reimbursement obligation.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Reimbursement obligation. 27.1239 Section 27... Policies Governing the Transition of the 2500-2690 Mhz Band for Brs and Ebs § 27.1239 Reimbursement obligation. (a) A proponent may request reimbursement from BRS licensees and lessees, EBS lessees, and...

Revising Sangiovanni's reciprocity-based internationalism: towards international egalitarian obligations

Directory of Open Access Journals (Sweden)

Conor Heaney

2016-06-01

Full Text Available To whom do we owe obligations of socio-economic justice? How are such obligations generated? Internationalism denotes a range of approaches to these questions. This paper examines Andrea Sangiovanni's—an internationalist—response to these questions. Sangiovanni argues that we owe egalitarian obligations only to those in the state, and that egalitarian obligations are generated through relationships of ‘reciprocity’. His is a ‘reciprocity-based internationalism’ (RBI. RBI has two components—one normative and another empirical. In this paper, I will assume the normative component, but reject its empirical component. My rejection of the empirical component has normative implications for RBI, which generate egalitarian obligations beyond the state. In other words, my revision of RBI is an argument in favour of international egalitarian obligations not generated through cosmopolitanism, but through internationalism.

5 CFR 2635.809 - Just financial obligations.

Science.gov (United States)

2010-01-01

... obligations. Employees shall satisfy in good faith their obligations as citizens, including all just financial... employee or reduced to judgment by a court. In good faith means an honest intention to fulfill any just...

Social categories as markers of intrinsic interpersonal obligations.

Science.gov (United States)

Rhodes, Marjorie; Chalik, Lisa

2013-06-01

Social categorization is an early-developing feature of human social cognition, yet the role that social categories play in children's understanding of and predictions about human behavior has been unclear. In the studies reported here, we tested whether a foundational functional role of social categories is to mark people as intrinsically obligated to one another (e.g., obligated to protect rather than harm). In three studies, children (aged 3-9, N = 124) viewed only within-category harm as violating intrinsic obligations; in contrast, they viewed between-category harm as violating extrinsic obligations defined by explicit rules. These data indicate that children view social categories as marking patterns of intrinsic interpersonal obligations, suggesting that a key function of social categories is to support inferences about how people will relate to members of their own and other groups.

Is there a moral obligation not to infect others?

Science.gov (United States)

Harris, J; Holm, S

1995-11-04

The emergence of HIV infection and AIDS has refocused concern on the obligations surrounding the carrying and transmission of communicable diseases. This article asks three related questions: Is there a general duty not to spread contagion? Are there special obligations not to communicate disease in the workplace? And does the mode of transmission of the disease affect the ethics of transmission and, if so, how and to what extent? There seems to be a strong prima facie obligation not to harm others by making them ill where this is avoidable, and this obligation not to communicate disease applies as much to relatively trivial diseases like the common cold as it does to HIV disease. The reasonableness of expecting people to live up to this obligation, however, depends on society reciprocating the obligation in the form of providing protection and compensation.

Lessee's obligations under the oil and gas lease

International Nuclear Information System (INIS)

Malcolm, R.T.

1998-01-01

Obligations of a lessee under the present day freehold petroleum and natural gas lease are described. The effect of recent cases relating to fiduciary and good faith duties on the lessee's obligations are also examined. Every lease under the Canadian Association of Petroleum Landmen (CAPL) must specifically deal with rights to be granted, the obligations to drill, royalties, the length of the primary term, the amount of the rental rights, rights to pool, and offset obligations. In Alberta, the most accepted petroleum and natural gas lease form is the CAPL 91. This form is presently being revised to create the 1998 version. The contents of this discussion included: (1) historical lease interpretation, (2) fiduciary obligations, (3) the definition of the doctrine of good faith, (4) implied and express covenants, (5) application of the default clause and (6) force majeur provisions. Although Alberta law does not recognize the doctrine of good faith, nevertheless the court will review the obligations of the lessee and if they do not feel that the lessee has acted fairly with respect to the lessor and damages have resulted, the court will find for the lessor

Whistleblowing and the bioethicist's public obligations.

Science.gov (United States)

MacDougall, D Robert

2014-10-01

Bioethicists are sometimes thought to have heightened obligations by virtue of the fact that their professional role addresses ethics or morals. For this reason it has been argued that bioethicists ought to "whistleblow"--that is, publicly expose the wrongful or potentially harmful activities of their employer--more often than do other kinds of employees. This article argues that bioethicists do indeed have a heightened obligation to whistleblow, but not because bioethicists have heightened moral obligations in general. Rather, the special duties of bioethicists to act as whistleblowers are best understood by examining the nature of the ethical dilemma typically encountered by private employees and showing why bioethicists do not encounter this dilemma in the same way. Whistleblowing is usually understood as a moral dilemma involving conflicting duties to two parties: the public and a private employer. However, this article argues that this way of understanding whistleblowing has the implication that professions whose members identify their employer as the public-such as government employees or public servants--cannot consider whistleblowing a moral dilemma, because obligations are ultimately owed to only one party: the public. The article contends that bioethicists--even when privately employed--are similar to government employees in the sense that they do not have obligations to defer to the judgments of those with private interests. Consequently, bioethicists may be considered to have a special duty to whistleblow, although for different reasons than those usually cited.

Displacement and gratitude: accounting for the political obligation of refugees

Directory of Open Access Journals (Sweden)

Jason D'Cruz

2014-03-01

Full Text Available On what basis, and to what extent, are refugees obligated to obey the laws of their host countries? Consideration of the specific case of asylum-seekers generates, I think, two competing intuitions: (1 the refugee has a prima facie obligation to obey the laws of her host country and (2 none of the popularly canvassed substrates of political obligation—consent, tacit consent, fairness, or social role—is at all apt to explain the presence of this obligation. I contend that the unfashionable gratitude account of political obligation does the best job of accounting for the intuitions. As has been noticed by other commentators, obligations of gratitude are difficult to specify and subject to numerous cancelling conditions. I analyze these conditions in detail and conclude that if one accepts that gratitude is the basis of the political obligation of the refugee, then one must face up to just how frangible the obligation is. In particular, the obligation is conditional on the fair and generous treatment of refugees that is consistent with their dignity as human beings.

Bystander Obligations at the Domestic and International Level Compared

NARCIS (Netherlands)

Spijkers, Otto|info:eu-repo/dai/nl/328454559

2014-01-01

This article examines whether States have a legal obligation to assist victims of serious breaches of fundamental obligations owed to the international community as a whole. This so-called ‘bystander State responsibility’ is compared with a similar legal obligation to assist victims at the domestic

24 CFR 266.415 - Mortgage lien and other obligations.

Science.gov (United States)

2010-04-01

... determine, that all contractual obligations in connection with the mortgage transaction, including the... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Mortgage lien and other obligations... Mortgage and Closing Requirements; HUD Endorsement § 266.415 Mortgage lien and other obligations. (a) Liens...

Is there a moral obligation not to infect others?

Science.gov (United States)

Harris, J.; Holm, S.

1995-01-01

The emergence of HIV infection and AIDS has refocused concern on the obligations surrounding the carrying and transmission of communicable diseases. This article asks three related questions: Is there a general duty not to spread contagion? Are there special obligations not to communicate disease in the workplace? And does the mode of transmission of the disease affect the ethics of transmission and, if so, how and to what extent? There seems to be a strong prima facie obligation not to harm others by making them ill where this is avoidable, and this obligation not to communicate disease applies as much to relatively trivial diseases like the common cold as it does to HIV disease. The reasonableness of expecting people to live up to this obligation, however, depends on society reciprocating the obligation in the form of providing protection and compensation. Images p1216-a p1216-b p1217-a PMID:7488907

Inability and Obligation in Moral Judgment

Science.gov (United States)

Buckwalter, Wesley; Turri, John

2015-01-01

It is often thought that judgments about what we ought to do are limited by judgments about what we can do, or that “ought implies can.” We conducted eight experiments to test the link between a range of moral requirements and abilities in ordinary moral evaluations. Moral obligations were repeatedly attributed in tandem with inability, regardless of the type (Experiments 1–3), temporal duration (Experiment 5), or scope (Experiment 6) of inability. This pattern was consistently observed using a variety of moral vocabulary to probe moral judgments and was insensitive to different levels of seriousness for the consequences of inaction (Experiment 4). Judgments about moral obligation were no different for individuals who can or cannot perform physical actions, and these judgments differed from evaluations of a non-moral obligation (Experiment 7). Together these results demonstrate that commonsense morality rejects the “ought implies can” principle for moral requirements, and that judgments about moral obligation are made independently of considerations about ability. By contrast, judgments of blame were highly sensitive to considerations about ability (Experiment 8), which suggests that commonsense morality might accept a “blame implies can” principle. PMID:26296206

7 CFR 1755.27 - Borrower contractual obligations.

Science.gov (United States)

2010-01-01

... 7 Agriculture 11 2010-01-01 2010-01-01 false Borrower contractual obligations. 1755.27 Section 1755.27 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE... CONTRACT FORMS § 1755.27 Borrower contractual obligations. (a) Loan agreement. As a condition of a loan or...

Review of International Experience with Renewable Energy Obligation Support Mechanisms

Energy Technology Data Exchange (ETDEWEB)

Wiser, R.

2005-06-01

The main policy instruments currently used in the EU Member States to achieve the targets set for electricity produced from renewable energy sources are: (1) the quota obligation system; (2) the feed-in tariff system; and (3) the tendering system. The current study aims to review the experience gained with the quota obligation system. The report provides an overview of the regions where obligation systems have been implemented and contains a detailed evaluation of the performance of the obligation systems in the USA, the UK and in Sweden. The obligation systems in these countries have been evaluated based on the following criteria: Effectiveness; Market efficiency; Certainty for the renewable energy industry; Cost effectiveness; Stakeholder support for the obligation system; and Equity. The evaluation of international experiences with the obligation system gives rise to a mixed picture. Although an obligation in theory is effective and cost effective, it seems too early to conclude that the system delivers these promises in practice. On the one hand this is due to the limited period of implementation that makes it hard to distinguish between the direct effect of the system and some teething problems that will be solved in due time. On the other hand, the conclusion can be drawn that the obligation is a complex system, which will only function well if designed carefully. It does seem worthwhile, however, to continue monitoring the experiences with the obligation system abroad, because this will further reveal whether the system is indeed effective and cost effective in practice. In the longer term, e.g. beyond 2010, the introduction of an obligation system in the Netherlands could be considered. Finally, as the design of support schemes is being improved, it appears that the basic concepts of both the obligation system and the feed in system have been refined in such a way that the two systems are gradually converging. An important difference between the two systems

Effectiveness of qualitative and quantitative security obligations

NARCIS (Netherlands)

Pieters, Wolter; Padget, J.; Dechesne, F.; Dignum, V.; Aldewereld, H.

Security policies in organisations typically take the form of obligations for the employees. However, it is often unclear what the purpose of such obligations is, and how these can be integrated in the operational processes of the organisation. This can result in policies that may be either too

Morphology and Phylogeny of a New Species of Anaerobic Ciliate, Trimyema finlayi n. sp., with Endosymbiotic Methanogens.

Science.gov (United States)

Lewis, William H; Sendra, Kacper M; Embley, T Martin; Esteban, Genoveva F

2018-01-01

Many anaerobic ciliated protozoa contain organelles of mitochondrial ancestry called hydrogenosomes. These organelles generate molecular hydrogen that is consumed by methanogenic Archaea, living in endosymbiosis within many of these ciliates. Here we describe a new species of anaerobic ciliate, Trimyema finlayi n. sp., by using silver impregnation and microscopy to conduct a detailed morphometric analysis. Comparisons with previously published morphological data for this species, as well as the closely related species, Trimyema compressum , demonstrated that despite them being similar, both the mean cell size and the mean number of somatic kineties are lower for T. finlayi than for T. compressum , which suggests that they are distinct species. This was also supported by analysis of the 18S rRNA genes from these ciliates, the sequences of which are 97.5% identical (6 substitutions, 1479 compared bases), and in phylogenetic analyses these sequences grouped with other 18S rRNA genes sequenced from previous isolates of the same respective species. Together these data provide strong evidence that T. finlayi is a novel species of Trimyema , within the class Plagiopylea. Various microscopic techniques demonstrated that T. finlayi n. sp. contains polymorphic endosymbiotic methanogens, and analysis of the endosymbionts' 16S rRNA gene showed that they belong to the genus Methanocorpusculum , which was confirmed using fluorescence in situ hybridization with specific probes. Despite the degree of similarity and close relationship between these ciliates, T. compressum contains endosymbiotic methanogens from a different genus, Methanobrevibacter . In phylogenetic analyses of 16S rRNA genes, the Methanocorpusculum endosymbiont of T. finlayi n. sp. grouped with sequences from Methanomicrobia, including the endosymbiont of an earlier isolate of the same species, ' Trimyema sp.,' which was sampled approximately 22 years earlier, at a distant (∼400 km) geographical location

Morphology and Phylogeny of a New Species of Anaerobic Ciliate, Trimyema finlayi n. sp., with Endosymbiotic Methanogens

Directory of Open Access Journals (Sweden)

William H. Lewis

2018-02-01

Full Text Available Many anaerobic ciliated protozoa contain organelles of mitochondrial ancestry called hydrogenosomes. These organelles generate molecular hydrogen that is consumed by methanogenic Archaea, living in endosymbiosis within many of these ciliates. Here we describe a new species of anaerobic ciliate, Trimyema finlayi n. sp., by using silver impregnation and microscopy to conduct a detailed morphometric analysis. Comparisons with previously published morphological data for this species, as well as the closely related species, Trimyema compressum, demonstrated that despite them being similar, both the mean cell size and the mean number of somatic kineties are lower for T. finlayi than for T. compressum, which suggests that they are distinct species. This was also supported by analysis of the 18S rRNA genes from these ciliates, the sequences of which are 97.5% identical (6 substitutions, 1479 compared bases, and in phylogenetic analyses these sequences grouped with other 18S rRNA genes sequenced from previous isolates of the same respective species. Together these data provide strong evidence that T. finlayi is a novel species of Trimyema, within the class Plagiopylea. Various microscopic techniques demonstrated that T. finlayi n. sp. contains polymorphic endosymbiotic methanogens, and analysis of the endosymbionts’ 16S rRNA gene showed that they belong to the genus Methanocorpusculum, which was confirmed using fluorescence in situ hybridization with specific probes. Despite the degree of similarity and close relationship between these ciliates, T. compressum contains endosymbiotic methanogens from a different genus, Methanobrevibacter. In phylogenetic analyses of 16S rRNA genes, the Methanocorpusculum endosymbiont of T. finlayi n. sp. grouped with sequences from Methanomicrobia, including the endosymbiont of an earlier isolate of the same species, ‘Trimyema sp.,’ which was sampled approximately 22 years earlier, at a distant (∼400 km

Antibiotic-resistant obligate anaerobes during exacerbations of cystic fibrosis patients.

Science.gov (United States)

Worlitzsch, D; Rintelen, C; Böhm, K; Wollschläger, B; Merkel, N; Borneff-Lipp, M; Döring, G

2009-05-01

Pseudomonas aeruginosa and Staphylococcus aureus are thought to cause the majority of lung infections in patients with cystic fibrosis (CF). However, other bacterial pathogens may contribute to the pathophysiology of lung disease. Here, obligate anaerobes were identified in a cross-sectional study, and cell numbers and antibiotic susceptibilities of facultative and obligate anaerobes from 114 sputum samples from nine children and 36 adults with CF were determined. Furthermore, in 12 CF patients, we investigated whether conventional intravenous antibiotic therapy, administered during acute exacerbations, would affect the numbers of obligate anaerobes. Fifteen genera of obligate anaerobes were identified in 91% of the CF patients. Cell numbers (mean: 2.2 x 10(7) +/- standard deviation 6.9 x 10(7) CFU/mL of sputum sample) were comparable to those of P. aeruginosa and S. aureus. Staphylococcus saccharolyticus and Peptostreptococcus prevotii were most prevalent. Infection with P. aeruginosa did not increase the likelihood that obligate anaerobes are present in sputum specimens. Single obligate anaerobic species persisted for up to 11 months in sputum plugs in vivo. Patients with and without obligate anaerobes in sputum specimens did not differ in lung function. Intravenous therapy directed against P. aeruginosa during acute exacerbations increased lung function, but did not reduce the numbers of obligate anaerobes. Obligate anaerobic species differed widely in their patterns of resistance against meropenem, piperacillin-tazobactam, clindamycin, metronidazole and ceftazidime. In 58% of patients with acute exacerbations, obligate anaerobes were detected that were resistant to the antibiotics used for treatment. Antibiotic therapy, optimized to target anaerobes in addition to P. aeruginosa, may improve the management of CF lung disease.

Singer's Utilitarian Account of Cosmopolitan Obligations: A Critical ...

African Journals Online (AJOL)

based conception of cosmopolitan obligations. Singer's thesis, simply put, is that from the perspective of utilitarian and cosmopolitan considerations, the affluent owe a moral obligation to provide aid to the masses of the poor irrespective of whether ...

Regular periodical public disclosure obligations of public companies

Directory of Open Access Journals (Sweden)

Marjanski Vladimir

2011-01-01

Full Text Available Public companies in the capacity of capital market participants have the obligation to inform the public on their legal and financial status, their general business operations, as well as on the issuance of securities and other financial instruments. Such obligations may be divided into two groups: The first group consists of regular periodical public disclosures, such as the publication of financial reports (annual, semi-annual and quarterly, and the management's reports on the public company's business operations. The second group comprises the obligation of occasional (ad hoc public disclosure. The thesis analyses the obligation of public companies to inform the public in course of their regular reporting. The new Capital Market Law based on two EU Directives (the Transparency Directive and the Directive on Public Disclosure of Inside Information and the Definition of Market Manipulation regulates such obligation of public companies in substantially more detail than the prior Law on the Market of Securities and Other Financial Instruments (hereinafter: ZTHV. Due to the above the ZTHV's provisions are compared to the new solutions within the domain of regular periodical disclosure of the Capital Market Law.

The obligation to contract in British law

Directory of Open Access Journals (Sweden)

Verena Klappstein

2014-06-01

Full Text Available Nowadays the obligation to contract is rarely looked upon. Without reason though, because it is neither outdated nor inoperable. Based on three common law doctrines the obligation to contract goes back to the Middle Ages. It has not lost its relevance, as it can still be found in modern statutory law, such as in the electricity and mail sector. What is more, it is a fundamental institution with a great impact. The analysis showed that the five chosen forms of obligations to contract bear analogical requirements but very similar rationales and economic consequences. It sets impaired market power right and it overstrikes irrational behaviour of market participants. As overall achievement it aligns the range of property, freedom of contract and freedom of competition.

Few Considerations on the Maintenance Obligation in the Romanian Civil Law

Directory of Open Access Journals (Sweden)

Mirela Costache

2017-08-01

Full Text Available Objectives: Recently entered into force, the Romanian Civil Code, systematized on the stable and steady values of the former civil law, reforms the matter of the maintenance obligation, regardless of the source and the legal nature of this obligation. Prior Work: This is the reason why we have chosen this topic and the analysis of the typology to which such an obligation adapts and, of course, the correlative right to which it gives birth. Approach: In our current system of law there are provided different forms of exercising this obligation, preserving, improving, but also innovating, in some aspects, the previous regulation. Specifically, we will relate in this study to a brief analysis of all types of maintenance obligations, generated by two distinct sources: the law and the will of the parties (contract, in this case we are speaking of an obligation based on the law or a contractual obligation. The angle from which we are analyzing this type of obligational relationship between the maintenance creditor and the maintenance debtor also allows us to recall both the passive or active patrimonial side, and also the analysis of the legal characters that it presupposes each of the two above-mentioned generic types of maintenance obligations. Value: Starting from the conceptualization of the maintenance obligation, the present study will be oriented towards the analysis in the current legal context of the doctrinal points of view expressed in the specialized literature, using as a method the documentary research, the interpretative method and the comparative method.

ACCESSORIES OF FISCAL OBLIGATION. LEGAL REGIME

Directory of Open Access Journals (Sweden)

RADA POSTOLACHE

2012-05-01

Full Text Available The interest – which is an institution typical to private law, has been taken over by the fiscal field and adapted to the specific features of fiscal obligation – being defined by its imperative legal regime, which has at the least the following characteristic elements: unitary character, imposed legal percentage, compulsory demand of interest, automatic application. In order to render responsible fiscal debtors, the lawmaker has reintroduced, as an accessory of fiscal obligation, delayed payment penalties, which have a distinct nature and legal regime, but without the principle non bis in idem being transgressed. Our study aims to establish the legal regime ofaccessories typical to fiscal obligation, from the perspective of special normative acts, but also of the common law within the field – Civil Code and Government Ordinance No. 13/2011 – by pointing out at the same time both the particular circumstances and procedural ones regulated by the Fiscal Procedure Code, shedding light upon the controversial legal nature of accessories.

12 CFR 13.100 - Obligations concerning institutional customers.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Obligations concerning institutional customers... GOVERNMENT SECURITIES SALES PRACTICES Interpretations § 13.100 Obligations concerning institutional customers... to institutional customers. (b) The OCC's suitability rule (§ 13.4) is fundamental to fair dealing...

7 CFR 400.166 - Obligations of the Corporation.

Science.gov (United States)

2010-01-01

... 7 Agriculture 6 2010-01-01 2010-01-01 false Obligations of the Corporation. 400.166 Section 400... CORPORATION, DEPARTMENT OF AGRICULTURE GENERAL ADMINISTRATIVE REGULATIONS Reinsurance Agreement-Standards for... Corporation. The Agreement will include the following among the obligations of the Corporation. (a) The...

Endosymbiotic copepods may feed on zooxanthellae from their coral host, Pocillopora damicornis

Science.gov (United States)

Cheng, Y.-R.; Dai, C.-F.

2010-03-01

The Xarifiidae is one of the most common families of endosymbiotic copepods that live in close association with scleractinian corals. Previous studies on xarifiids primarily focused on their taxonomy and morphology, while their influence on corals is still unknown. In this study, we collected a total of 1,579 individuals belonging to 6 species of xarifiids from 360 colonies of Pocillopora damicornis at Nanwan Bay, southern Taiwan from July 2007 to May 2008. Furthermore, using optical and electron microscopic observations, we examined the gut contents of Xarifia fissilis, the most abundant species of the Xarifiidae that we collected. We found that the gut of X. fissilis was characterized by a reddish-brown color due to the presence of numerous unicellular algae with diameters of 5-10 μm. TEM observations indicated that the unicellular algae possessed typical characteristics of Symbiodinium including a peripheral chloroplast, stalked pyrenoids, starch sheaths, mesokaryotic nuclei, amphiesmas, an accumulation body, and mitochondria. After starving the isolated X. fissilis in the light and dark (light intensity: 140 μmol photon m-2 s-1; photoperiod: 12 h light/12 h dark) for 2 weeks, fluorescence was clearly visible in its gut and fecal pellets under fluorescent microscopic observations. The cultivation experiment supports the hypothesis that the unicellular algae were beneficial to the survival of X. fissilis under light conditions, possibly through transferring photosynthates to the hosts. These results suggest that X. fissilis may consume and retain unicellular algae for further photosynthesis.

The impact of regulatory obligations on fishers’ income

DEFF Research Database (Denmark)

Hadjimichael, Maria; J. Kaiser, Michel; Edwards-Jones, Gareth

2013-01-01

as a marketing tool to identify fishers’ most and least preferred regulatory obligations in terms of the impact these obligations have on their income. Significant differences were identified in fishers’ preferences that depended on the regulatory measures fishers operated under at the time of the study (which...

16 CFR 436.2 - Obligation to furnish documents.

Science.gov (United States)

2010-01-01

... AND PROHIBITIONS CONCERNING FRANCHISING Franchisors' Obligations § 436.2 Obligation to furnish documents. In connection with the offer or sale of a franchise to be located in the United States of America... to the address specified by the prospective franchisee by first-class United States mail at least...

Is there a moral obligation not to infect others?

OpenAIRE

Harris, J.; Holm, S.

1995-01-01

The emergence of HIV infection and AIDS has refocused concern on the obligations surrounding the carrying and transmission of communicable diseases. This article asks three related questions: Is there a general duty not to spread contagion? Are there special obligations not to communicate disease in the workplace? And does the mode of transmission of the disease affect the ethics of transmission and, if so, how and to what extent? There seems to be a strong prima facie obligation not to harm ...

The Obligations of States towards Refugees under International Law

DEFF Research Database (Denmark)

Skordas, Achilles

The main purpose of the current study is to discuss the obligations of States towards refugees under international law, and to argue that States have obligations towards refugees regardless of the ratification of the Geneva Convention....

Deconfounding Distance Effects in Judgments of Moral Obligation

Science.gov (United States)

Nagel, Jonas; Waldmann, Michael R.

2013-01-01

A heavily disputed question of moral philosophy is whether spatial distance between agent and victim is normatively relevant for the degree of obligation to help strangers in need. In this research, we focus on the associated descriptive question whether increased distance does in fact reduce individuals' sense of helping obligation. One problem…

In the Nick of Time: Proactive Prevention of Obligation Violations

DEFF Research Database (Denmark)

Basin, David; Debois, Søren; Hildebrandt, Thomas

2016-01-01

We present a system model, an enforcement mechanism, and a policy language for the proactive enforcement of timed provisions and obligations. Our approach improves upon existing formalisms in two ways: (1) we exploit the target system's existing functionality to avert policy violations proactively...... declaratively express timed provisions and obligations as causal relationships between events, and DCR states explicitly represent pending obligations. As key technical results, we show that enforceability of DCR policies is decidable, we give a sufficient polynomial time verifiable condition for a policy...... to be enforceable, and we give an algorithm for determining from a DCR state a sequence of actions that discharge impending obligations....

Novation as a method of termination of obligations

Directory of Open Access Journals (Sweden)

Perović Marko

2017-01-01

Full Text Available The paper presents an analysis of the issue of novation in contract law. Novation is a contract between the creditor and debtor in order to replace its existing obligation with a new one. Unlike the other methods of termination of obligations (e.g. fulfillment, compensation, remission of debt, novation extinguishes existing contractual relationship between the creditor and the debtor, so that among them arise a new contractual relationship, which in relation to the previous one, differs on the case or legal basis. In most of the modern codifications of civil law, novation obtained a particular use in relation to the classical Roman law, which included a change of persons in obligations. In Serbian law, novation also has took the particular use and it takes an important place among many other termination methods of obligations. The analysis made in this paper, focused to the theoretical arguments and practical significance of the novation, brings the author to the conclusions and recommendations relevant to the novation in the theory and practices of contract law.

19 CFR 4.94 - Yacht privileges and obligations.

Science.gov (United States)

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Yacht privileges and obligations. 4.94 Section 4... THE TREASURY VESSELS IN FOREIGN AND DOMESTIC TRADES General § 4.94 Yacht privileges and obligations...) A cruising license may be issued to a yacht of a foreign country only if it has been made to appear...

Engineering of obligate intracellular bacteria: progress, challenges and paradigms

Science.gov (United States)

Over twenty years have passed since the first report of genetic manipulation of an obligate intracellular bacterium. Through progress interspersed by bouts of stagnation, microbiologists and geneticists have developed approaches to genetically manipulate obligates. A brief overview of the current ge...

Obligations of low income countries in ensuring equity in global health financing.

Science.gov (United States)

Barugahare, John; Lie, Reidar K

2015-09-08

Despite common recognition of joint responsibility for global health by all countries particularly to ensure justice in global health, current discussions of countries' obligations for global health largely ignore obligations of developing countries. This is especially the case with regards to obligations relating to health financing. Bearing in mind that it is not possible to achieve justice in global health without achieving equity in health financing at both domestic and global levels, our aim is to show how fulfilling the obligation we propose will make it easy to achieve equity in health financing at both domestic and international levels. Achieving equity in global health financing is a crucial step towards achieving justice in global health. Our general view is that current discussions on global health equity largely ignore obligations of Low Income Country (LIC) governments and we recommend that these obligations should be mainstreamed in current discussions. While we recognise that various obligations need to be fulfilled in order to ultimately achieve justice in global health, for lack of space we prioritise obligations for health financing. Basing on the evidence that in most LICs health is not given priority in annual budget allocations, we propose that LIC governments should bear an obligation to allocate a certain minimum percent of their annual domestic budget resources to health, while they await external resources to supplement domestic ones. We recommend and demonstrate a mechanism for coordinating this obligation so that if the resulting obligations are fulfilled by both LIC and HIC governments it will be easy to achieve equity in global health financing. Although achieving justice in global health will depend on fulfillment of different categories of obligations, ensuring inter- and intra-country equity in health financing is pivotal. This can be achieved by requiring all LIC governments to allocate a certain optimal per cent of their domestic

Value, obligation and the asymmetry question.

Science.gov (United States)

Tooley, Michael

1998-04-01

Is there a prima facie obligation to produce additional individuals whose lives would be worth living? In his paper 'Is it good to make happy people?', Stuart Rachels argues not only that there is, but, also, that precisely as much weight should be assigned to the quality of life that would be enjoyed by such potential persons, if they were to be actualized, as to the quality of life enjoyed by actually existing persons. In response, I shall argue, first, that Rachels' view is exposed to very serious objections, and secondly, that his arguments in support of his position involve a crucial assumption, which cannot be sustained, concerning the relation between, on the one hand, propositions about good-making and bad-making properties, and, on the other, propositions about right-making and wrong-making ones. I shall then argue that there is a very plausible position concerning the conditions under which an action can be morally wrong which entails the following asymmetry: there is a prima facie obligation not to bring into existence individuals whose lives are not worth living, but there is no corresponding obligation to create additional individuals whose lives would be worth living.

Controls Over Unliquidated Obligations in the Iraq Relief and Reconstruction Fund

National Research Council Canada - National Science Library

Bowen, Stuart W

2007-01-01

.... Funds no longer needed may be deobligated. The purpose of this audit was to determine the amount of IRRF unliquidated obligations retained by DoD, DoS, and USAID and whether those agencies have established adequate management controls over their unliquidated obligations. This audit focused on annual reviews of unliquidated obligations that agencies should have completed for fiscal year 2006.

18 CFR 367.22 - Accounting for asset retirement obligations.

Science.gov (United States)

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Accounting for asset... GAS ACT General Instructions § 367.22 Accounting for asset retirement obligations. (a) An asset... measurement changes to the initial liability for the legal obligation recorded in account 230, Asset...

THE RELATIONSHIPBETWEEN NEUROTICISM AND JOB SATISFACTION

Directory of Open Access Journals (Sweden)

Numanovic Almedina

2013-12-01

Full Text Available Objective: In the narrowest sense job satisfaction is related with positive, emotional attachment of an individual to work. Greater number of researches consider that the job satisfaction include greater number of factors. On the other side the results of several studies show that there is a tendency towards higher positive correlations between different factors of job satisfaction suggesting the existence of one general factor towards work environment. Aim: The aim of the study was to determine the correlation between neoroticism and job satisfaction of teachers. Socio-demographics characzeristisc were also compared. Material andMethod: The study included 90 teachers, 44 (48,89% male and 46 (51,11% female, of primary school in Novi Pazar. The degree of neuroticism was measured using the test of general neuroticism, Cornell index, and job satisfaction using Questionnaire to test satisfaction with workplace and organization. Results: The obtained results show that there is moderate connection between neoroticism and job satisfaction. On the test of neuroticism, men showed far greater degree of neuroticism, both men and women showed the same degree of job satisfaction. On the CI-N4 test the older employees showed the higher degree of neuroticism than younger employees. Conclusion: It was discovered that there is a positive correlation between neuroticism and job satisfactions, in other words, as the person is more satisfied with job, neurotic symptoms are more expressed.

[Long-term storage of obligate anaerobic microorganisms in glycerol].

Science.gov (United States)

Briukhanov, A I; Netrusov, A I

2006-01-01

We evaluated the possibility of storing the cultures of obligate anaerobic microorganisms (clostridia. acetogenic and sulfate-reducing bacteria, and methanogenic archaea) in 25% glycerol at -70 degrees C for a long time (up to 3 years). This method of storage is adequate to preserve cell viability in most obligate anaerobes.

49 CFR 371.10 - Duties and obligations of brokers.

Science.gov (United States)

2010-10-01

... 49 Transportation 5 2010-10-01 2010-10-01 false Duties and obligations of brokers. 371.10 Section... SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS BROKERS OF PROPERTY § 371.10 Duties and obligations of brokers. Where the broker acts on behalf of a person bound by...

Collateralized debt obligations (CDOs

Directory of Open Access Journals (Sweden)

Dragosavac Miloš

2012-01-01

Full Text Available Collateralized debt obligations (CDOs were issued in 1987 by bankers at Drexel Burnham Lambert Inc. A decade later, CDOs became the leading power on the credit derivative markets, on which the value of derivative assets was derived from the value of other assets. However, unlike options and credit swamps, CDOs are not real, which means that they are constructed, and sometimes even the construction of their construction. CDOs were made to satisfy different types of investors, at one end, there is low-risk with low-income, and at the other, high-risk with high-income. By 2007, following the bubble burst on the US real estate market, losses on the CDO market started to expand. By 2008, the crisis on the CDO market turned into what we call today 'the global financial crisis.' CDOs are 'in the heart' of the crisis, and even wider. Our attempt is to reveal the mechanism of collateralized debt obligations (CDOs and the way in which CDOs expanded the negative effects of the present global financial crisis.

Advances in genetic manipulation of obligate intracellular bacterial pathogens

Directory of Open Access Journals (Sweden)

Paul eBeare

2011-05-01

Full Text Available Infections by obligate intracellular bacterial pathogens result in significant morbidity and mortality worldwide. These bacteria include Chlamydia spp., which causes millions of cases of sexually transmitted disease and blinding trachoma annually, and members of the α-proteobacterial genera Anaplasma, Ehrlichia, Orientia and Rickettsia, agents of serious human illnesses including epidemic typhus. Coxiella burnetii, the agent of human Q fever, has also been considered a prototypical obligate intracellular bacterium, but recent host cell-free (axenic growth has rescued it from obligatism. The historic genetic intractability of obligate intracellular bacteria has severely limited molecular dissection of their unique lifestyles and virulence factors involved in pathogenesis. Host cell restricted growth is a significant barrier to genetic transformation that can make simple procedures for free-living bacteria, such as cloning, exceedingly difficult. Low transformation efficiency requiring long term culture in host cells to expand small transformant populations is another obstacle. Despite numerous technical limitations, the last decade has witnessed significant gains in genetic manipulation of obligate intracellular bacteria including allelic exchange. Continued development of genetic tools should soon enable routine mutation and complementation strategies for virulence factor discovery and stimulate renewed interest in these refractory pathogens. In this review, we discuss the technical challenges associated with genetic transformation of obligate intracellular bacteria and highlight advances made with individual genera.

29 CFR 4.146 - Contract obligations after award, generally.

Science.gov (United States)

2010-07-01

... 29 Labor 1 2010-07-01 2010-07-01 true Contract obligations after award, generally. 4.146 Section 4.146 Labor Office of the Secretary of Labor LABOR STANDARDS FOR FEDERAL SERVICE CONTRACTS Application of the McNamara-O'Hara Service Contract Act Period of Coverage § 4.146 Contract obligations after...

Transience after disturbance: Obligate species recovery dynamics depend on disturbance duration.

Science.gov (United States)

Singer, Alexander; Johst, Karin

2017-06-01

After a disturbance event, population recovery becomes an important species response that drives ecosystem dynamics. Yet, it is unclear how interspecific interactions impact species recovery from a disturbance and which role the disturbance duration (pulse or press) plays. Here, we analytically derive conditions that govern the transient recovery dynamics from disturbance of a host and its obligately dependent partner in a two-species metapopulation model. We find that, after disturbance, species recovery dynamics depend on the species' role (i.e. host or obligately dependent species) as well as the duration of disturbance. Host recovery starts immediately after the disturbance. In contrast, for obligate species, recovery depends on disturbance duration. After press disturbance, which allows dynamics to equilibrate during disturbance, obligate species immediately start to recover. Yet, after pulse disturbance, obligate species continue declining although their hosts have already begun to increase. Effectively, obligate species recovery is delayed until a necessary host threshold occupancy is reached. Obligates' delayed recovery arises solely from interspecific interactions independent of dispersal limitations, which contests previous explanations. Delayed recovery exerts a two-fold negative effect, because populations continue declining to even smaller population sizes and the phase of increased risk from demographic stochastic extinction in small populations is prolonged. We argue that delayed recovery and its determinants -species interactions and disturbance duration - have to be considered in biodiversity management. Copyright © 2017 Elsevier Inc. All rights reserved.

Slovenia and Kyoto Obligation

International Nuclear Information System (INIS)

Tirsek, A.; Jevsek, F.; Plavcak, V.-P.

1998-01-01

The paper gives the possibilities of emission reduction as an obligation from Kyoto Protocol. The Slovenia environmental and energy strategies are regulated to implement the agreement to reduce the emissions of greenhouse gases by 8% to the year 2012 as regard the basic year 1986 in energy, transportation, industrial and other sectors, especially focused on electric power sector. (author)

21 CFR 312.52 - Transfer of obligations to a contract research organization.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Transfer of obligations to a contract research... and Investigators § 312.52 Transfer of obligations to a contract research organization. (a) A sponsor may transfer responsibility for any or all of the obligations set forth in this part to a contract...

USAID Dollars Obligated and Dollars Spent

Data.gov (United States)

US Agency for International Development — Displays obligations and disbursements by operating unit (OU) and sector, beginning with Fiscal Years 2009. The data was pulled from USAID's financial accounting...

Isolation of obligate and facultative anaerobic bacteria from feline subcutaneous abscesses.

Science.gov (United States)

Hoshuyama, S; Kanoe, M; Amimoto, A

1996-03-01

A total of 113 specimens collected from purulent skin lesions of household cats was examined bacteriologically. Ninety seven isolates obtained from 74 specimens (65.5%). Of these, 11 specimens (9.7%) contained obligate anaerobes only, 18 specimens (15.9%) yielded both obligate and facultative anaerobes. In the obligate anaerobes detected, genus Fusobacterium was the most frequently observed and F. nucleatum was most common species. Pasteurella multocida was the facultative anaerobe which was most frequently detected.

Filial anxiety and sense of obligation among offspring of Holocaust survivors.

Science.gov (United States)

Shrira, Amit; Menashe, Ravit; Bensimon, Moshe

2018-03-13

Much is known about adult children caring for their aging parents, yet the potentially unique experience of offspring caring for traumatized parents is underexplored. Therefore, the current studies assessed filial anxiety and sense of obligation among offspring of Holocaust survivors (OHS) in caring for their parents. In Study 1, we interviewed 10 OHS (mean age = 61.0) in order to extract themes of filial anxiety. Based on Study 1's data, a newly constructed scale of filial anxiety was administered in Study 2 to 59 adult offspring (mean age = 56.4): 28 OHS and 31 comparisons. Study 3 included 143 dyads of parents and offspring (mean age = 55.4 and 81.7, respectively): 86 Holocaust dyads and 57 comparison dyads. Parents reported posttraumatic stress disorder (PTSD) symptoms and offspring reported filial anxiety and sense of obligation. In Study 1, interviewees referred to concerns about parent experiencing decline alongside caregiving difficulties. In Study 2, OHS reported higher filial anxiety and sense of obligation relative to comparisons. This group difference was mediated by sense of obligation. In Study 3, OHS with parental PTSD reported higher filial anxiety and sense of obligation relative to comparisons. Once more, filial sense of obligation served as a mediator. In Studies 2-3, results remained significant after adjusting for offspring symptoms. Parental exposure to the Holocaust, and especially parental PTSD, related to higher filial obligation, which in turn was related to higher filial anxiety. These findings bear important implications for practitioners working with survivors' families.

Novation as a method of termination of obligations

OpenAIRE

Perović Marko

2017-01-01

The paper presents an analysis of the issue of novation in contract law. Novation is a contract between the creditor and debtor in order to replace its existing obligation with a new one. Unlike the other methods of termination of obligations (e.g. fulfillment, compensation, remission of debt), novation extinguishes existing contractual relationship between the creditor and the debtor, so that among them arise a new contractual relationship, which in relation to the previous one, differs on t...

The Endosymbiotic Bacterium Wolbachia Selectively Kills Male Hosts by Targeting the Masculinizing Gene.

Directory of Open Access Journals (Sweden)

Takahiro Fukui

2015-07-01

Full Text Available Pathogens are known to manipulate the reproduction and development of their hosts for their own benefit. Wolbachia is an endosymbiotic bacterium that infects a wide range of insect species. Wolbachia is known as an example of a parasite that manipulates the sex of its host's progeny. Infection of Ostrinia moths by Wolbachia causes the production of all-female progeny, however, the mechanism of how Wolbachia accomplishes this male-specific killing is unknown. Here we show for the first time that Wolbachia targets the host masculinizing gene of Ostrinia to accomplish male-killing. We found that Wolbachia-infected O. furnacalis embryos do not express the male-specific splice variant of doublesex, a gene which acts at the downstream end of the sex differentiation cascade, throughout embryonic development. Transcriptome analysis revealed that Wolbachia infection markedly reduces the mRNA level of Masc, a gene that encodes a protein required for both masculinization and dosage compensation in the silkworm Bombyx mori. Detailed bioinformatic analysis also elucidated that dosage compensation of Z-linked genes fails in Wolbachia-infected O. furnacalis embryos, a phenomenon that is extremely similar to that observed in Masc mRNA-depleted male embryos of B. mori. Finally, injection of in vitro transcribed Masc cRNA into Wolbachia-infected embryos rescued male progeny. Our results show that Wolbachia-induced male-killing is caused by a failure of dosage compensation via repression of the host masculinizing gene. Our study also shows a novel strategy by which a pathogen hijacks the host sex determination cascade.

Different Endosymbiotic Interactions in Two Hydra Species Reflect the Evolutionary History of Endosymbiosis

KAUST Repository

Ishikawa, Masakazu

2016-06-19

Endosymbiosis is an important evolutionary event for organisms, and there is widespread interest in understanding the evolution of endosymbiosis establishment. Hydra is one of the most suitable organisms for studying the evolution of endosymbiosis. Within the genus Hydra, H. viridissima and H. vulgaris show endosymbiosis with green algae. Previous studies suggested that the endosymbiosis in H. vulgaris took place much more recently than that in H. viridissima, noting that the establishment of the interaction between H. vulgaris and its algae is not as stable as in H. viridissima. To investigate the on-going process of endosymbiosis, we first compared growth and tolerance to starvation in symbiotic and aposymbiotic polyps of both species. The results revealed that symbiotic H. viridissima had a higher growth rate and greater tolerance to starvation than aposymbiotic polyps. By contrast, growth of symbiotic H. vulgaris was identical to that of aposymbiotic polyps, and symbiotic H. vulgaris was less tolerant to starvation. Moreover, our gene expression analysis showed a pattern of differential gene expression in H. viridissima similar to that in other endosymbiotically established organisms, and contrary to that observed in H. vulgaris. We also showed that H. viridissima could cope with oxidative stress that caused damage, such as cell death, in H. vulgaris. These observations support the idea that oxidative stress related genes play an important role in the on-going process of endosymbiosis evolution. The different evolutionary stages of endosymbiosis studied here provide a deeper insight into the evolutionary processes occurring toward a stable endosymbiosis.

Different Endosymbiotic Interactions in Two Hydra Species Reflect the Evolutionary History of Endosymbiosis

KAUST Repository

Ishikawa, Masakazu; Yuyama, Ikuko; Shimizu, Hiroshi; Nozawa, Masafumi; Ikeo, Kazuho; Gojobori, Takashi

2016-01-01

Endosymbiosis is an important evolutionary event for organisms, and there is widespread interest in understanding the evolution of endosymbiosis establishment. Hydra is one of the most suitable organisms for studying the evolution of endosymbiosis. Within the genus Hydra, H. viridissima and H. vulgaris show endosymbiosis with green algae. Previous studies suggested that the endosymbiosis in H. vulgaris took place much more recently than that in H. viridissima, noting that the establishment of the interaction between H. vulgaris and its algae is not as stable as in H. viridissima. To investigate the on-going process of endosymbiosis, we first compared growth and tolerance to starvation in symbiotic and aposymbiotic polyps of both species. The results revealed that symbiotic H. viridissima had a higher growth rate and greater tolerance to starvation than aposymbiotic polyps. By contrast, growth of symbiotic H. vulgaris was identical to that of aposymbiotic polyps, and symbiotic H. vulgaris was less tolerant to starvation. Moreover, our gene expression analysis showed a pattern of differential gene expression in H. viridissima similar to that in other endosymbiotically established organisms, and contrary to that observed in H. vulgaris. We also showed that H. viridissima could cope with oxidative stress that caused damage, such as cell death, in H. vulgaris. These observations support the idea that oxidative stress related genes play an important role in the on-going process of endosymbiosis evolution. The different evolutionary stages of endosymbiosis studied here provide a deeper insight into the evolutionary processes occurring toward a stable endosymbiosis.

Physicians' strikes and the competing bases of physicians' moral obligations.

Science.gov (United States)

MacDougall, D Robert

2013-09-01

Many authors have addressed the morality of physicians' strikes on the assumption that medical practice is morally different from other kinds of occupations. This article analyzes three prominent theoretical accounts that attempt to ground such special moral obligations for physicians--practice-based accounts, utilitarian accounts, and social contract accounts--and assesses their applicability to the problem of the morality of strikes. After critiquing these views, it offers a fourth view grounding special moral obligations in voluntary commitments, and explains why this is a preferable basis for understanding physicians' moral obligations in general and especially as pertaining to strikes.

Observer perceptions of moral obligations in groups with a history of victimization.

Science.gov (United States)

Warner, Ruth H; Branscombe, Nyla R

2012-07-01

The authors investigated when observers assign contemporary group members moral obligations based on their group's victimization history. In Experiment 1, Americans perceived Israelis as obligated to help Sudanese genocide victims and as guiltworthy for not helping if reminded of the Holocaust and its descendants were linked to this history. In Experiment 2, participants perceived Israelis as more obligated to help and guiltworthy for not helping when the Holocaust was presented as a unique victimization event compared with when genocide was presented as pervasive. Experiments 3 and 4 replicated the effects of Experiment 1 with Cambodians as the victimized group. Experiment 5 demonstrated that participants perceived Cambodians as having more obligations under high just world threat compared with low just world threat. Perceiving victimized groups as incurring obligations is one just world restoration method of providing meaning to collective injustice.

The moral obligation to be vaccinated: utilitarianism, contractualism, and collective easy rescue.

Science.gov (United States)

Giubilini, Alberto; Douglas, Thomas; Savulescu, Julian

2018-02-10

We argue that individuals who have access to vaccines and for whom vaccination is not medically contraindicated have a moral obligation to contribute to the realisation of herd immunity by being vaccinated. Contrary to what some have claimed, we argue that this individual moral obligation exists in spite of the fact that each individual vaccination does not significantly affect vaccination coverage rates and therefore does not significantly contribute to herd immunity. Establishing the existence of a moral obligation to be vaccinated (both for adults and for children) despite the negligible contribution each vaccination can make to the realisation of herd immunity is important because such moral obligation would strengthen the justification for coercive vaccination policies. We show that two types of arguments-namely a utilitarian argument based on Parfit's Principle of Group Beneficence and a contractualist argument-can ground an individual moral obligation to be vaccinated, in spite of the imperceptible contribution that any single vaccination makes to vaccine coverage rates. We add a further argument for a moral obligation to be vaccinated that does not require embracing problematic comprehensive moral theories such as utilitarianism or contractualism. The argument is based on a "duty of easy rescue" applied to collectives, which grounds a collective moral obligation to realise herd immunity, and on a principle of fairness in the distribution of the burdens that must be borne to realise herd immunity.

Should Social Value Obligations be Local or Global?

Science.gov (United States)

Nayak, Rahul; Shah, Seema K

2017-02-01

According to prominent bioethics scholars and international guidelines, researchers and sponsors have obligations to ensure that the products of their research are reasonably available to research participants and their communities. In other words, the claim is that research is unethical unless it has local social value. In this article, we argue that the existing conception of reasonable availability should be replaced with a social value obligation that extends to the global poor (and not just research participants and host communities). To the extent the social value requirement has been understood as geographically constrained to the communities that host research and the countries that can afford the products of research, it has neglected to include the global poor as members of the relevant society. We argue that a new conception of social value obligations is needed for two reasons. First, duties of global beneficence give reason for researchers, sponsors, and institutions to take steps to make their products more widely accessible. Second, public commitments made by many institutions acknowledge and engender responsibilities to make the products of research more accessible to the global poor. Future research is needed to help researchers and sponsors discharge these obligations in ways that unlock their full potential. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.

Misleading by Omission: Rethinking the Obligation to Inform Research Subjects about Funding Sources.

Science.gov (United States)

Manson, Neil C

2017-11-15

Informed consent requirements for medical research have expanded over the past half-century. The Declaration of Helsinki now includes an explicit positive obligation to inform subjects about funding sources. This is problematic in a number of ways and seems to oblige researchers to disclose information irrelevant to most consent decisions. It is argued here that such a problematic obligation involves an "informational fallacy." The aim in the second part of the paper is to provide a better approach to making sense of how a failure to inform about funding sources wrongs subjects: by making appeals to obligations to refrain from misleading by omission. This alternative approach-grounded in a general obligation to refrain from misleading, an obligation that is independent of informed consent-provides a basis for a norm that protects subjects' interests, without the informational fallacy. The approach developed here avoids the problems identified with the currently specified general obligation to inform about funding sources. © The Author 2017. Published by Oxford University Press, on behalf of the Journal of Medicine and Philosophy Inc. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

25 CFR 163.42 - Obligated service and breach of contract.

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Obligated service and breach of contract. 163.42 Section... breach of contract. (a) Obligated service. (1) Individuals completing forestry education programs with an... request for waiver. (b) Breach of contract. Any individual who has participated in and accepted financial...

Informed consent: Enforcing pharmaceutical companies' obligations abroad.

Science.gov (United States)

Lee, Stacey B

2010-06-15

The past several years have seen an evolution in the obligations of pharmaceutical companies conducting clinical trials abroad. Key players, such as international human rights organizations, multinational pharmaceutical companies, the United States government and courts, and the media, have played a significant role in defining these obligations. This article examines how such obligations have developed through the lens of past, present, and future recommendations for informed consent protections. In doing so, this article suggests that, no matter how robust obligations appear, they will continue to fall short of providing meaningful protection until they are accompanied by a substantive enforcement mechanism that holds multinational pharmaceutical companies accountable for their conduct. Issues of national sovereignty, particularly in the United States, will continue to prevent meaningful enforcement by an international tribunal or through one universally adopted code of ethics. This article argues that, rather than continuing to pursue an untenable international approach, the Alien Torts Statute (ATS) offers a viable enforcement mechanism, at least for US-based pharmaceutical companies. Recent federal appellate court precedent interpreting the ATS provides the mechanism for granting victims redress and enforcing accountability of sponsors (usually pharmaceutical companies and research and academic institutions) for informed consent misconduct. Substantive human rights protections are vital in order to ensure that every person can realize the "right to health." This article concludes that by building on the federal appellate court's ATS analysis, which grants foreign trial participants the right to pursue claims of human rights violations in US courts, a mechanism can be created for enforcing not only substantive informed consent, but also human rights protections.

Family obligation values as a protective and vulnerability factor among low-income adolescent girls.

Science.gov (United States)

Milan, Stephanie; Wortel, Sanne

2015-06-01

Adolescents' beliefs about family obligation often reflect cultural variations in their family context, and thus are important for understanding development among diverse youth. In this study, we test hypotheses about the role of family obligation values in risk behavior and mental health in a sample of 194 low-income adolescent girls (mean age = 15.2; 58% Latina, 28% African-American/Black). We hypothesized that family obligation values can be both a protective and vulnerability factor, depending on the type of outcome and the presence of other risk factors. Across the sample, higher family obligation values tended to occur with indicators of positive family functioning (e.g., more frequent communication, less maternal hostility) based on mother and adolescent reports. As hypothesized, family obligation values moderated the relationship between established risk factors and adjustment in distinct ways, such that high family obligation values decreased risk in some domains (i.e., a protective factor) but increased risk in other domains (i.e., a vulnerability factor). Specifically, high family obligation values diminished the relationship between peer norms for risky behavior (sex and substance use) and individual engagement in those behaviors. At the same time, high family obligation values magnified the relationship between exposure to negative life events and poor mental health (PTSD and depressive symptoms). The results suggest that family obligation is an important but complex aspect of development among diverse adolescent girls.

Family Obligation Values as a Protective and Vulnerability Factor among Low-Income Adolescent Girls

Science.gov (United States)

Milan, Stephanie; Wortel, Sanne

2014-01-01

Adolescents’ beliefs about family obligation often reflect cultural variations in their family context, and thus are important for understanding development among diverse youth. In this study, we test hypotheses about the role of family obligation values in risk behavior and mental health in a sample of 194 low-income adolescent girls (Mean age = 15.2; 58% Latina, 28% African-American/Black). We hypothesized that family obligation values can be both a protective and vulnerability factor, depending on the type of outcome and the presence of other risk factors. Across the sample, higher family obligation values tended to occur with indicators of positive family functioning (e.g., more frequent communication, less maternal hostility) based on mother and adolescent reports. As hypothesized, family obligation values moderated the relationship between established risk factors and adjustment in distinct ways, such that high family obligation values decreased risk in some domains (i.e., a protective factor) but increased risk in other domains (i.e., a vulnerability factor). Specifically, high family obligation values diminished the relationship between peer norms for risky behavior (sex and substance use) and individual engagement in those behaviors. At the same time, high family obligation values magnified the relationship between exposure to negative life events and poor mental health (PTSD and depressive symptoms). The results suggest that family obligation is an important but complex aspect of development among diverse adolescent girls. PMID:25351163

[The right to self-determination versus the obligation to protect one's health].

Science.gov (United States)

Höfling, Wolfram

2009-01-01

"Individual responsibility" and the abidance by any "health-related obligations" are key words of the present political and legal German healthcare debate. In the process of adjusting the German welfare state by focussing the ideal allocation of common health resources patients who do not meet their "health-related obligations" are thus expected to accept cutbacks in medical care services. However, from the perspective of constitutional law there is no "health-related obligation" deriving from the German constitution - the right to self-determination guaranteed in Art. 2 Sect. 2 Sent. 1 of the German constitution has not been amended to impose a corresponding duty. Hence, health-related obligations may only refer to indirect ways of exercising individual responsibility, no more and no less. The present article highlights the few possibilities which the German constitution provides for the implementation of "health-related obligations" and reminds us of the conceptual aspects which have to be considered by the legislator.

Family Obligations in Denmark

DEFF Research Database (Denmark)

Koch-Nielsen, Inger

How is the balance in obligations between the Family and the Danish Welfare State? Can we observe a trend to shift the responsibility back to the family? This booklet intends to sketch the legal framework around the division of responsibilities between the Family and the state and to analyse...... to what extent and where the unit of rights and obliagations is the individual and where it is the family or household....

Contractual and non-contractuall obligations in private international Law

OpenAIRE

Čejková, Martina

2010-01-01

67 8 Summary 8.1 Contractual and Non-contractual Obligations in Private International Law This thesis deals with the European international private law and discusses the current law-crash modification of contractual and non-contractual obligations. Characteristic of the European community is the absence of unification of the substantive law, which is compensated, by the unification of conflict standards. The unification of conflict standards, as an instrument of the international private law,...

30 CFR 717.11 - General obligations.

Science.gov (United States)

2010-07-01

... construction, operation, and reclamation of shafts, adits, underground support facilities, underground mining... Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR INITIAL PROGRAM REGULATIONS UNDERGROUND MINING GENERAL PERFORMANCE STANDARDS § 717.11 General obligations. (a...

Manipulation of Host Cholesterol by Obligate Intracellular Bacteria

Directory of Open Access Journals (Sweden)

Dhritiman Samanta

2017-05-01

Full Text Available Cholesterol is a multifunctional lipid that plays important metabolic and structural roles in the eukaryotic cell. Despite having diverse lifestyles, the obligate intracellular bacterial pathogens Chlamydia, Coxiella, Anaplasma, Ehrlichia, and Rickettsia all target cholesterol during host cell colonization as a potential source of membrane, as well as a means to manipulate host cell signaling and trafficking. To promote host cell entry, these pathogens utilize cholesterol-rich microdomains known as lipid rafts, which serve as organizational and functional platforms for host signaling pathways involved in phagocytosis. Once a pathogen gains entrance to the intracellular space, it can manipulate host cholesterol trafficking pathways to access nutrient-rich vesicles or acquire membrane components for the bacteria or bacteria-containing vacuole. To acquire cholesterol, these pathogens specifically target host cholesterol metabolism, uptake, efflux, and storage. In this review, we examine the strategies obligate intracellular bacterial pathogens employ to manipulate cholesterol during host cell colonization. Understanding how obligate intracellular pathogens target and use host cholesterol provides critical insight into the host-pathogen relationship.

The levels of disclosure relating to mine closure obligations by platinum mining companies

Directory of Open Access Journals (Sweden)

Joline Sturdy

2017-06-01

Aim: The aim of this study is to establish the extent to which platinum mines listed on the Johannesburg Stock Exchange (JSE comply with a recommended disclosure framework. Setting: South Africa is the largest producer of platinum in the world. The study covers all platinum mines listed on the JSE. Methods: Using a framework, a census of the annual financial statements, integrated annual reports and sustainability reports or websites was conducted to determine the level of compliance of disclosure relating to mine closure obligations to the recommended disclosure framework. Results: The results show disclosure relating to mine closure obligations of platinum mines listed on the JSE is inconsistent and not sufficient for stakeholders to understand the scope, key assumptions, parameters or reliability of the assessment and calculation of mine closure obligations. Conclusion: The assumptions used to determine mine closure obligations are specialised and multi-disciplinary. The accuracy and reliability of mine closure obligations will improve dramatically through greater transparency and access to information. It is recommended that the JSE listings for mining companies should require a competent person’s report to provide disclosure on assumptions, key values and processes applied to determine the mine closure obligations. Furthermore, it is recommended that the Department of Mineral Resources implements a mechanism of independent assessment of mine closure obligations by experts on an ongoing basis.

[Analysis of DNA-DNA homologies in obligate methylotrophic bacteria].

Science.gov (United States)

Doronina, N V; Govorukhina, N I; Lysenko, A M; Trotsenko, Iu A

1988-01-01

The genotypic affinity of 19 bacterial strains obligately dependent on methanol or methylamine as carbon and energy sources was studied by techniques of molecular DNA hybridization. The high homology level (35-88%) between motile strain Methylophilus methanolovorus V-1447D and nonmotile strain Methylobacillus sp. VSB-792 as well as other motile strains (Pseudomonas methanolica ATCC 21704, Methylomonas methanolica NRRL 5458, Pseudomonas sp. W6, strain A3) indicates that all of them belong to one genus. Rather high level of homology (62-63%) was found between Methylobacillus glycogenes ATCC 29475 and Pseudomonas insueta ATCC 21276 and strain G-10. The motile strain Methylophilus methylotrophus NCIB 10515 has a low homology (below 20%) to other of the studied obligate methylobacteria. Therefore, at least two genetically different genera of obligate methylobacteria can be distinguished, namely Methylophilus and Methylobacillus, the latter being represented by both motile and nonmotile forms.

Post-trial obligations in the Declaration of Helsinki 2013: classification, reconstruction and interpretation.

Science.gov (United States)

Mastroleo, Ignacio

2016-08-01

The general aim of this article is to give a critical interpretation of post-trial obligations towards individual research participants in the Declaration of Helsinki 2013. Transitioning research participants to the appropriate health care when a research study ends is a global problem. The publication of a new version of the Declaration of Helsinki is a great opportunity to discuss it. In my view, the Declaration of Helsinki 2013 identifies at least two clearly different types of post-trial obligations, specifically, access to care after research and access to information after research. The agents entitled to receive post-trial access are the individual participants in research studies. The Declaration identifies the sponsors, researchers and host country governments as the main agents responsible for complying with the post-trial obligations mentioned above. To justify this interpretation of post-trial obligations, I first introduce a classification of post-trial obligations and illustrate its application with examples from post-trial ethics literature. I then make a brief reconstruction of the formulations of post-trial obligations of the Declaration of Helsinki from 2000 to 2008 to correlate the changes with some of the most salient ethical arguments. Finally I advance a critical interpretation of the latest formulation of post-trial obligations. I defend the view that paragraph 34 of 'Post-trial provisions' is an improved formulation by comparison with earlier versions, especially for identifying responsible agents and abandoning ambiguous 'fair benefit' language. However, I criticize the disappearance of 'access to other appropriate care' present in the Declaration since 2004 and the narrow scope given to obligations of access to information after research. © 2015 John Wiley & Sons Ltd.

SLDP: a novel protein related to caleosin is associated with the endosymbiotic Symbiodinium lipid droplets from Euphyllia glabrescens.

Science.gov (United States)

Pasaribu, Buntora; Lin, I-Ping; Tzen, Jason T C; Jauh, Guang-Yuh; Fan, Tung-Yung; Ju, Yu-Min; Cheng, Jing-O; Chen, Chii-Shiarng; Jiang, Pei-Luen

2014-10-01

Intracellular lipid droplets (LDs) have been proposed to play a key role in the mutualistic endosymbiosis between reef-building corals and the dinoflagellate endosymbiont Symbiodinium spp. This study investigates and identifies LD proteins in Symbiodinium from Euphyllia glabrescens. Discontinuous Percoll gradient centrifugation was used to separate Symbiodinium cells from E. glabrescens tentacles. Furthermore, staining with a fluorescent probe, Nile red, indicated that lipids accumulated in that freshly isolated Symbiodinium cells and lipid analyses further showed polyunsaturated fatty acids (PUFA) was abundant. The stable LDs were purified from endosymbiotic Symbiodinium cells. The structural integrity of the Symbiodinium LDs was maintained via electronegative repulsion and steric hindrance possibly provided by their surface proteins. Protein extracts from the purified LDs revealed a major protein band with a molecular weight of 20 kDa, which was termed Symbiodinium lipid droplet protein (SLDP). Interestingly, immunological cross-recognition analysis revealed that SLDP was detected strongly by the anti-sesame and anti-cycad caleosin antibodies. It was suggested that the stable Symbiodinium LDs were sheltered by this unique structural protein and was suggested that SLDP might be homologous to caleosin to a certain extent.

Parental responses to child support obligations

DEFF Research Database (Denmark)

Rossin-Slater, Maya; Wüst, Miriam

find that larger obligations are associated with higher new-partner fertility among both parents. The maternal fertility response is consistent with a positive income-fertility relationship, while the paternal fertility response may reflect increased demand for new offspring as a result of reduced...

THEORETICAL ASPECTS REGARDING THE OBLIGATION AS PROVIDED BY THE ROMANIAN LEGISLATION AND THE DOCTRINE

Directory of Open Access Journals (Sweden)

Bogdan NAZAT

2015-07-01

Full Text Available Taking into consideration the latest amendments of the Romanian civil legislation performed through the Civil code of 2009, as further amended, I consider useful to provide the lecturers with a theoretical overview over one of the most important institution in our legal environment, i.e. the obligation. The analyse will start with an introduction comprising the definition of the obligation as provided by the Civil code aand the doctrina, will continue with the structure of the obligation and, further, will offer an overview of its sources, identifying, inter alia, the articles in the Civil code where such sources are regulated (e.g. contract, law. In the end, the paper will provide a doctrinaire classification of the obligation, outlining the main categories of the obligations.

18 CFR 346.3 - Asset retirement obligations.

Science.gov (United States)

2010-04-01

... related to asset retirement obligations that would impact the calculation of rate base, such as carrier property and related accumulated depreciation and accumulated deferred income taxes, may not be reflected...

18 CFR 35.18 - Asset retirement obligations.

Science.gov (United States)

2010-04-01

... related to asset retirement obligations that would impact the calculation of rate base, such as electric plant and related accumulated depreciation and accumulated deferred income taxes, may not be reflected...

18 CFR 37.5 - Obligations of Transmission Providers and Responsible Parties.

Science.gov (United States)

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Obligations of Transmission Providers and Responsible Parties. 37.5 Section 37.5 Conservation of Power and Water Resources... ACCESS SAME-TIME INFORMATION SYSTEMS § 37.5 Obligations of Transmission Providers and Responsible Parties...

29 CFR 4.177 - Discharging fringe benefit obligations by equivalent means.

Science.gov (United States)

2010-07-01

... 29 Labor 1 2010-07-01 2010-07-01 true Discharging fringe benefit obligations by equivalent means... CONTRACTS Compensation Standards Compliance with Compensation Standards § 4.177 Discharging fringe benefit obligations by equivalent means. (a) In general. (1) Section 2(a)(2) of the Act, which provides for fringe...

Competition law and the obligation to supply

DEFF Research Database (Denmark)

Bergqvist, Christian

2015-01-01

While accepted in theory and practice that an obligation to supply, ser-vice or license can emerge under competition law, the scope of this is subject to many, if not lacunas, at least ambiguities, and no general ob-li¬gations of such nature can, no should, be identified. Further, and equally...... important, the narrow set of circumstances warranting inter-vention against refusals is defined by competition law in accordance with its underlying principles of a predominantly economic nature. Hence, competition law should not be relied upon as a corrective in-strument to lacunas in other areas of law, e.......g. compulsory licenses un-der IP law. Below, some considerations regarding the obligation to supply under competition law are offered for the purpose of correcting the misunderstandings....

Post-trial obligations - DOI: 10.3395/reciis.v2.Sup1.210en

Directory of Open Access Journals (Sweden)

Doris Schroeder

2008-12-01

Full Text Available In its essence, post-trial obligations describe a duty by research sponsors to provide a successfully tested drug to research participants who took part in the relevant clinical trials after the trial has been concluded. In some instances, this duty is extended beyond the research participants. This article is divided into three main parts. The first part outlines the legal basis for post-trial obligations by looking at international guidelines, including those issued by the World Medical Association. National legislation is exemplified through resolutions and guidelines issued by Brazil and South Africa respectively. The second part analyses the ethical foundation for post-trial obligations, in particular the attempt to minimize exploitation of research subjects. The third part raises obstacles and challenges for the implementation of post-trial obligations. The jury is still out on whether post-trial obligations in the form of access to drugs for clinical trial participants is the best, or even a good way, to avoid exploitation in medical research.

28 CFR 43.2 - Obligations of persons receiving care and treatment.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Obligations of persons receiving care and treatment. 43.2 Section 43.2 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) RECOVERY OF COST OF HOSPITAL AND MEDICAL CARE AND TREATMENT FURNISHED BY THE UNITED STATES § 43.2 Obligations of persons...

The logic of actual obligation. An alternative approach to deontic logic

NARCIS (Netherlands)

Voorbraak, F.

In this paper we develop a system of deontic logic (LAO, the logic of actual obligation) with a rather limited scope: we are, only interested in obligations as far as they: are relevant for deciding what actions actually ought to be done in a particular situation, given some normative system N.

Effectiveness of Nigeria's international obligations in curbing ...

African Journals Online (AJOL)

Effectiveness of Nigeria's international obligations in curbing domestic violence. ... Nnamdi Azikiwe University Journal of International Law and Jurisprudence ... This paper examines the issue of domestic violence in Nigeria to determine the ...

18 CFR 154.315 - Asset retirement obligations.

Science.gov (United States)

2010-04-01

... retirement obligations that would impact the calculation of rate base, such as gas plant and related accumulated depreciation and accumulated deferred income taxes, may not be reflected in rates and must be...

Report on the installations of cogeneration under obligation to buy; Rapport sur les installations de cogeneration sous obligation d'achat

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-01-15

Facing the problem of the climatic change and the increase of the fossil energies prices, the government policy of the cogeneration development follows many objectives. Among these objectives it is necessary of implement a new tariff of obligation to buy of the electricity from cogeneration and allow the existing installations to reaffirm their obligation to buy contract. The first part of this report defines the necessary conditions to better use the ecological and economical interest of the natural gas cogeneration and shows that these conditions are not favorable in France. The second part preconizes to modify the actual tariff device in order to maintain the existing park to 2015 in acceptable economical and ecological conditions. (A.L.B.)

SDC Supplier Obligation project : household energy from 2011 : final report

OpenAIRE

Sustainable Development Commission

2008-01-01

This report is based on 'SDC Supplier Obligation engagement project : process plan'. Evaluation of the engagement process used in this report can be found in 'SDC Supplier Obligation project : an evaluation of the Sustainable Development Commission's stakeholder and public engagement process'. This report presents the findings of the Sustainable Development Commission’s stakeholder and public engagement process and informs the development of Department for Environment, Food and Rural Af...

The 'special obligations' of the modern Hippocratic Oath for 21st century medicine.

Science.gov (United States)

Holmboe, Eric; Bernabeo, Elizabeth

2014-01-01

Profound advances and discoveries in medicine have markedly improved the lives of many over the 50 years since the modern Hippocratic Oath was written. Regrettably, these advances were and continue to be implemented suboptimally and inequitably across the globe. 'Special obligations to all my fellow humans' is an important theme of the modern Oath. From this perspective, we reflect on the special obligations of the medical profession, and examine how these obligations have changed over the past 50 years. We draw from perspectives of the social contract, professionalism, quality improvement, patient safety and a group of 31 international colleagues involved in medical education as we examine these obligations for individual doctors, health care institutions and medical education systems. The perspectives of the 31 clinician-educators helped us to situate the meaning of the theme of 'special obligations' in the context of challenges facing medical education and health care in the 21st century. Improving the quality of care and patient safety, and reducing health care disparities are now paramount as 'special obligations' for doctors, health care systems and medical education organisations, and require us to work collectively and collaboratively in an increasingly interconnected world. In our view, traditions such as the Hippocratic Oath will be worthy of public support only when the medical profession demonstrates in meaningful and transparent ways that it is meeting its social and civic obligations to make the world, not just health care, a better place. © 2013 John Wiley & Sons Ltd.

47 CFR 76.56 - Signal carriage obligations.

Science.gov (United States)

2010-10-01

... qualified local NCE station affiliated with a State public television network shall not be required to carry... stations in fulfillment of these must-carry obligations may do so, subject to approval by the franchising...

Why patients have a moral obligation to give care to clinicians.

Science.gov (United States)

Buetow, Stephen

2014-12-01

Progress is being made in transitioning from clinicians who are torn between caring for patients and populations, to clinicians who are partnering with patients to care for patients as people. However, the focus is still on what patients and others can do for patients, however defined. For clinicians whose interests must be similarly respected for their own sake and because they are integrally related to those of patients, what can and should patients do? Patients can be exempted from some normal social roles but are generally recognized to have moral obligations in health care. One of these obligations is caregiving to clinicians within the limits of each patient's capability. My paper moves this obligation beyond the ceremonial order of etiquette characterizing public statements on how patients should relate to others. It goes beyond a patient-centred ethic that is consumerist in nature, to a person-centred one that recognizes patients typically as moral agents who are dignified by recognizing the obligation to give as well as receive care as sincere benevolence. This obligation derives objective justification from divine command. It is also consistent, however, both with what people, if ignorant of their social role, would objectively produce for a hypothetical social contract, and with virtues constitutive of human nature and a relational and communitarian understanding of what it is to be a person. Including sentiment (intuition) and personal conscience, this relational identity makes caregiving intrinsically meaningful, yet caregiving also has an instrumental value to patients and clinicians. Its self-enforcement by patients will depend on their moral code and on society making caregiving achievable for them. A moral obligation for patient caregiving may then be specified to require patients to reflect on and invest in relationships in which they can feel and show care for others sincerely and respectfully. © 2014 John Wiley & Sons, Ltd.

29 CFR 500.60 - Farm labor contractors' recruitment, contractual and general obligations.

Science.gov (United States)

2010-07-01

... labor contractors' recruitment, contractual and general obligations. The Act imposes certain specific recruitment, contractual and general obligations on farm labor contractors and farm labor contractor employees... 29 Labor 3 2010-07-01 2010-07-01 false Farm labor contractors' recruitment, contractual and...

Assignments of rights and obligations under a gas sales contract

International Nuclear Information System (INIS)

Kowch, J.R.M.

1996-01-01

A general overview of the principles of assignment in a gas sales contract was presented. Assignment is a process wherein the rights or obligations under a contract are transferred from one of the contracting parties to a third party. It is, in other words, the introduction of a new party to the original contractual relationship. Under the rights and obligations of a gas sales contract, the most important right of the seller is to have its gas taken and to be paid. Likewise, the most important obligation of the buyer is to take the gas and pay for it. An assignment by either party has the potential to alter the original expectations of the parties or the basis of which they committed to the contract in the first place. Prior to deregulation and unbundling initiatives, gas sellers and buyers could enter a 20 year sales contract and deal exclusively with each other over the entire 20 year term. Since deregulation, there are more players, and a higher level of corporate acquisitions, divestitures, rationalizations, and restructuring. Today, there are greater chances than ever before that the original party to a contract may change, or that certain rights and obligations may be assigned to a third party and affect the expectations under the contract

Material obligations: Forms and content

International Nuclear Information System (INIS)

Johnson, L.

1998-01-01

This paper includes a detailed legal framework of the IAEA safeguards agreements, namely basic articles of the IAEA Statute, Treaty and Supply Agreement obligations and basic documents concerning decisions and practices of the Board of Governors. It describes as well the initiation process of the negotiation of safeguards agreements, contents comparison and implementation of the safeguards agreements, protocols to safeguards agreements, subsidiary arrangements, amendments and renegotiation documents

Global Redistributive Obligations in the Face of Severe Poverty

DEFF Research Database (Denmark)

Axelsen, David Vestergaard

? In the debate on global justice, a number of theorists argue that this discrepancy can indeed be justified (so-called anti-cosmopolitans). Thus, to bring us closer to answer regarding our redistributive obligations towards foreigners, I analyze and evaluate such arguments. My critical examination reveals...... comprehensive obligations to foreigners and compatriots simultaneously. Thus, even if we are duty-bound to redistribute comprehensively to compatriots, this does not entail that we could not also do so towards non-compatriots. Hence, their arguments are incomplete. Thirdly, I show that anti...

The landing obligation in view of different management regimes

DEFF Research Database (Denmark)

Frost, Hans Staby; Hoff, Ayoe

2017-01-01

The European Union adopted a landing obligation in 2015 implying that all catches of fish subject to quota management must be landed. We compare and contrast the economic consequences for fisheries of the landing obligation in view of the management system on which it is super-imposed. Four types...... the strongest influence on both industry profitability and catch of unwanted species in the case of management with shared non-transferable quotas. In addition, the move from management with shared quotas to individual transferable quotas (ITQ) increases industry profitability and reduces unwanted catches...

45 CFR 660.11 - What are the Director's obligations in interstate situations?

Science.gov (United States)

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false What are the Director's obligations in interstate... SCIENCE FOUNDATION INTERGOVERNMENTAL REVIEW OF THE NATIONAL SCIENCE FOUNDATION PROGRAMS AND ACTIVITIES § 660.11 What are the Director's obligations in interstate situations? (a) The Director is responsible...

A cross-cultural study of noblesse oblige in economic decision-making.

Science.gov (United States)

Fiddick, Laurence; Cummins, Denise Dellarosa; Janicki, Maria; Lee, Sean; Erlich, Nicole

2013-09-01

A cornerstone of economic theory is that rational agents are self-interested, yet a decade of research in experimental economics has shown that economic decisions are frequently driven by concerns for fairness, equity, and reciprocity. One aspect of other-regarding behavior that has garnered attention is noblesse oblige, a social norm that obligates those of higher status to be generous in their dealings with those of lower status. The results of a cross-cultural study are reported in which marked noblesse oblige was observed on a reciprocal-contract decision-making task. Participants from seven countries that vary along hierarchical and individualist/collectivist social dimensions were more tolerant of non-reciprocation when they adopted a high-ranking perspective compared with a low-ranking perspective.

THE SELLER'S OBLIGATION TO DELIVER THE GOODS ACCORDING TO CISG

Directory of Open Access Journals (Sweden)

Dan VELICU

2017-05-01

Full Text Available This article aims to analyze the seller's obligations under the Convention on International Sale of Goods (CISG and in particular the obligation to deliver the goods showing the main issues that arise in an international sale. We also wish to point the major innovations or improvements brought by the CISG in comparison to the European civil codes regulation and to conclude if the CSIG managed to revolutionize the tradition view on this issue.

Energy supplier obligations and white certificate schemes: Comparative analysis of experiences in the European Union

Energy Technology Data Exchange (ETDEWEB)

Bertoldi, Paolo, E-mail: paolo.bertoldi@ec.europa.e [European Commission, Joint Research Centre, Institute for Energy, Via E. Fermi 1, TP 450, 21027 Ispra (Vatican City State, Holy See) (Italy); Rezessy, Silvia, E-mail: silvia.rezessy@ec.europa.e [European Commission, Joint Research Centre, Institute for Energy, Via E. Fermi 1, TP 450, 21027 Ispra (Vatican City State, Holy See) (Italy); Lees, Eoin, E-mail: eoin@eoinleesenergy.co [Eoin Lees Energy, 4 Silver Lane, West Challow, Wantage, Oxon OX12 9TX (United Kingdom); Baudry, Paul, E-mail: paul.baudry@edf.f [EDF R and D, Centre des Renardieres, 77818 Moret sur Loing (France); Jeandel, Alexandre, E-mail: alexandre.jeandel@gdfsuez.co [GDF SUEZ, 16, rue Ville L' Eveque, 75008 Paris (France); Labanca, Nicola, E-mail: nicola.labanca@polimi.i [eERG, Politecnico di Milano, Via Lambruschini n. 4, 20156 Milano (Italy)

2010-03-15

A number of Member States of the European Union (EU) have introduced market-based policy portfolios based on quantified energy savings obligations on energy distributors or suppliers, possibly coupled with certification of project-based energy savings (via white certificates), and the option to trade the certificates or obligations. The paper provides an up-to-date review and analysis of results to date of white certificate schemes in the EU. In the EU supplier obligations and white certificate schemes have delivered larger savings than originally expected with obliged companies exceeding targets and, in some cases, at cost below what policy makers have anticipated. Supplier obligations foster the uptake of standardised energy efficiency actions often targeting smaller energy users (residential sector), lowering the transaction costs and contributing to market transformation. The role of certificate trading is more ambiguous. Trading can bring benefits where the target is set sufficiently high with respect to the energy-saving potential in the sectors covered. Theoretically trading may be better suited for broader systems with comprehensive coverage, but even in smaller schemes trading may reduce the transaction costs of compliance for obliged actors without sufficient expertise on end-use energy efficiency. Yet, trading increases the administrative cost ratio of energy-saving obligations.

Energy supplier obligations and white certificate schemes: Comparative analysis of experiences in the European Union

International Nuclear Information System (INIS)

Bertoldi, Paolo; Rezessy, Silvia; Lees, Eoin; Baudry, Paul; Jeandel, Alexandre; Labanca, Nicola

2010-01-01

A number of Member States of the European Union (EU) have introduced market-based policy portfolios based on quantified energy savings obligations on energy distributors or suppliers, possibly coupled with certification of project-based energy savings (via white certificates), and the option to trade the certificates or obligations. The paper provides an up-to-date review and analysis of results to date of white certificate schemes in the EU. In the EU supplier obligations and white certificate schemes have delivered larger savings than originally expected with obliged companies exceeding targets and, in some cases, at cost below what policy makers have anticipated. Supplier obligations foster the uptake of standardised energy efficiency actions often targeting smaller energy users (residential sector), lowering the transaction costs and contributing to market transformation. The role of certificate trading is more ambiguous. Trading can bring benefits where the target is set sufficiently high with respect to the energy-saving potential in the sectors covered. Theoretically trading may be better suited for broader systems with comprehensive coverage, but even in smaller schemes trading may reduce the transaction costs of compliance for obliged actors without sufficient expertise on end-use energy efficiency. Yet, trading increases the administrative cost ratio of energy-saving obligations.

Report on the installations of cogeneration under obligation to buy; Rapport sur les installations de cogeneration sous obligation d'achat

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-01-15

Facing the problem of the climatic change and the increase of the fossil energies prices, the government policy of the cogeneration development follows many objectives. Among these objectives it is necessary of implement a new tariff of obligation to buy of the electricity from cogeneration and allow the existing installations to reaffirm their obligation to buy contract. The first part of this report defines the necessary conditions to better use the ecological and economical interest of the natural gas cogeneration and shows that these conditions are not favorable in France. The second part preconizes to modify the actual tariff device in order to maintain the existing park to 2015 in acceptable economical and ecological conditions. (A.L.B.)

Support Seeking or Familial Obligation: An Investigation of Motives for Disclosing Genetic Test Results.

Science.gov (United States)

Greenberg, Marisa; Smith, Rachel A

2016-01-01

Genetic test results reveal not only personal information about a person's likelihood of certain medical conditions but also information about the person's genetic relatives. Given the familial nature of genetic information, one's obligation to protect family members may be a motive for disclosing genetic test results, but this claim has not been methodically tested. Existing models of disclosure decision making presume self-interested motives, such as seeking social support, instead of other-interested motives, like familial obligation. This study investigated young adults' (N = 173) motives to share a genetic-based health condition, alpha-1 antitrypsin deficiency, after reading a hypothetical vignette. Results show that social support and familial obligation were both reported as motives for disclosure. In fact, some participants reported familial obligation as their primary motivator for disclosure. Finally, stronger familial obligation predicted increased likelihood of disclosing hypothetical genetic test results. Implications of these results were discussed in reference to theories of disclosure decision-making models and the practice of genetic disclosures.

Les contextes de l’obligation de reclassement Contexts of the reclassification obligation Los contextos de la obligación a la reclasificación

Directory of Open Access Journals (Sweden)

Serge Frossard

2010-02-01

Full Text Available En droit français, le reclassement des salariés a émergé dans des hypothèses précises et, dans la plupart des cas, sous l’impulsion des hautes juridictions, Cour de cassation ou Conseil d’État. Le législateur est intervenu a posteriori pour consacrer une obligation de reclassement déjà dégagée en jurisprudence ou en germe. Le contexte dans lequel cette obligation s’est construite permet d’expliquer ce qui caractérise son champ d’application. L’emploi, plus exactement la préservation du lien d’emploi, y joue un rôle central et fédérateur. Mais à la différence du droit québécois, la discrimination reste distincte et même si son champ recoupe celui de l’obligation de reclassement, on ne peut intégrer celle-ci dans celle-là. Ces constats permettent d’orienter la recherche des fondements juridiques de l’obligation de reclassement. Plus que sur une analyse de droit des contrats, quand bien même celle-ci serait renouvelée, l’obligation de reclassement peut s’appuyer sur un droit de valeur constitutionnel : le droit d’obtenir un emploi. À l’échelle des règles internationales, ce dernier peut également s’adosser à plusieurs textes, dont un s’est vu reconnaître une portée considérable en droit français.In French law, worker reclassification emerged under precise assumptions and, in most cases, under the impetus of the high jurisdictions, the Cour de Cassation or the Conseil d’Etat. The legislator intervened a posteriori to legitimize a reclassification obligation already emerging in jurisprudence or in the process of being created. The context in which this obligation was built makes it possible to explain what characterizes its field of application. Employment, or more exactly the safeguarding of employment, plays a central and federator role in it. But unlike Quebec law, discrimination remains distinct and even if its field transects that of the reclassification obligation, it cannot

A de-novo-assembly-based Data Analysis Pipeline for Plant Obligate Parasite Metatranscriptomic Studies

Directory of Open Access Journals (Sweden)

Li Guo

2016-07-01

Full Text Available Current and emerging plant diseases caused by obligate parasitic microbes such as rusts, downy mildews, and powdery mildews threaten worldwide crop production and food safety. These obligate parasites are typically unculturable in the laboratory, posing technical challenges to characterize them at the genetic and genomic level. Here we have developed a data analysis pipeline integrating several bioinformatic software programs. This pipeline facilitates rapid gene discovery and expression analysis of a plant host and its obligate parasite simultaneously by next generation sequencing of mixed host and pathogen RNA (i.e. metatranscriptomics. We applied this pipeline to metatranscriptomic sequencing data of sweet basil (Ocimum basilicum and its obligate downy mildew parasite Peronospora belbahrii, both lacking a sequenced genome. Even with a single data point, we were able to identify both candidate host defense genes and pathogen virulence genes that are highly expressed during infection. This demonstrates the power of this pipeline for identifying genes important in host-pathogen interactions without prior genomic information for either the plant host or the obligate biotrophic pathogen. The simplicity of this pipeline makes it accessible to researchers with limited computational skills and applicable to metatranscriptomic data analysis in a wide range of plant-obligate-parasite systems.

Changes in perceived filial obligation norms among coresident family caregivers in Japan.

Science.gov (United States)

Tsutsui, Takako; Muramatsu, Naoko; Higashino, Sadanori

2014-10-01

Japan introduced a nationwide long-term care insurance (LTCI) system in 2000, making long-term care (LTC) a right for older adults regardless of income and family availability. To shed light on its implications for family caregiving, we investigated perceived filial obligation norms among coresident primary family caregivers before and after the policy change. Descriptive and multiple regression analyses were conducted to examine changes in perceived filial obligation norms and its subdimensions (financial, physical, and emotional support), using 2-wave panel survey data of coresident primary family caregivers (N = 611) in 1 city. The baseline survey was conducted in 1999, and a follow-up survey 2 years later. On average, perceived filial obligation norms declined (p family caregivers. In particular, physical support, which Japan's LTC reform targeted, declined significantly among daughters and daughters-in-law (p perceived filial obligation norms after the policy introduction than sons and daughters (p < .01 and p < .05, respectively), controlling for the baseline filial obligation and situational factors. Our research indicates declining roles of daughters-in-law in elder care during Japan's LTCI system implementation period. Further international efforts are needed to design and implement longitudinal studies that help promote understanding of the interplay among national LTC policies, social changes, and caregiving norms and behaviors. © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America.

78 FR 46418 - Proposed Information Collection (Obligation To Report Factors Affecting Entitlement) Activity...

Science.gov (United States)

2013-07-31

... (Obligation To Report Factors Affecting Entitlement) Activity; Comment Request AGENCY: Veterans Benefits... use of other forms of information technology. Title: Obligation to Report Factors Affecting... entitlement factors. Individual factors such as income, marital status, and the beneficiary's number of...

The social ascription of obligations to engineers

NARCIS (Netherlands)

Busby, J.S.; Coeckelbergh, Mark

2003-01-01

Discovering obligations that are ascribed to them by others is potentially an important element in the development of the moral imagination of engineers. Moral imagination cannot reasonably be developed by contemplating oneself and one’s task alone: there must be some element of discovering the

45 CFR 1226.13 - Obligations of sponsors.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false Obligations of sponsors. 1226.13 Section 1226.13 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE PROHIBITIONS ON ELECTORAL AND LOBBYING ACTIVITIES Sponsor Employee Activities § 1226.13...

The relationship between family obligation and religiosity on caregiving.

Science.gov (United States)

Epps, Fayron

2014-01-01

The purpose of this study was to examine the relationship between family obligation and religiosity on the positive appraisal of caregiving among African-American, Hispanic and non-Hispanic Caucasian family caregivers of older adults. Roy's adaptation model guided formulation of the aims and study design. A cross-sectional, correlational study design was employed to examine the relationship amongst variables for the family caregiver participants. Study participants (N = 69) completed a demographic tool and four instruments the: (1) Katz index, (2) obligation scale, (3) Duke University religion index, and (4) positive appraisal of care scale. There was a significant correlation between family obligation and positive appraisal of caregiving. However, there was no relationship between the family caregiver's religiosity and positive appraisal of caregiving overall. Demographic variables were also examined to show a higher marginal mean for Hispanic primary caregivers in relation to the positive appraisal of caregiving. Future studies should consider replicating these findings in a larger sample to provide health care professionals with substantial evidence to incorporate culturally sensitive interventions aimed at promoting positive outcomes and healthy family behaviors. Copyright © 2014 Mosby, Inc. All rights reserved.

34 CFR 611.44 - Under what circumstances may the Secretary defer a scholarship recipient's service obligation?

Science.gov (United States)

2010-07-01

... a scholarship recipient's service obligation? (a) Upon written request, the Secretary may defer a service obligation for a scholarship recipient who— (1) Has not begun teaching in a high-need school of a... scholarship recipient's service obligation? 611.44 Section 611.44 Education Regulations of the Offices of the...

Pricing in quota obligation schemes for renewable energy. A stochastic model with reference to the Swedish quota obligation; Preisbildung in Quotenmodellen zur Foerderung Erneuerbarer Energien. Modellierung mit stochastischem Ansatz am Beispiel des schwedischen Quotenmodells

Energy Technology Data Exchange (ETDEWEB)

Dees, Philipp

2013-12-11

The PhD thesis develops a stochastic model to explain pricing in Quota Obligation schemes for renewable energy (RE). It is based on the fact that electricity production from RE is depending on weather and other conditions, which leads to a random fluctuation. In the developed model the price for RE is depending on the probability of a lack of certificates at the end of an obligation period. In contrast to deterministic models, the stochastic model has a direct link between the price for RE and their high investment costs. Moreover, the stochastic model can be used to describe the development of prices over an obligation period. The model is adopted to the Swedish quota obligation. It is shown that the real RE prices there are much higher than the estimated prices derived from the model. This result is consistent to the fact that installed RE capacity in Sweden is much higher than necessary to fulfill the quota obligation.

Development of a personal obligation to shift electricity use: Initial determinants and maintenance over time

Energy Technology Data Exchange (ETDEWEB)

Linz, D.; Heberlein, T.

1984-03-01

The present study is an attempt to determine if the beliefs which underly the formation of an obligation to shift electricity use among household consumers also contribute to maintenance of the obligation over time. Utility customer beliefs about and obligation toward shifting electricity use in their households from on-peak to off-peak times were examined in 1977, when the customers had no behavioral experience with electricity shifting. In 1979, after two years of experience with shifting appliance use from on-peak to off-peak times, customers were again surveyed and the same variables measured. The results indicated that the formation of a feeling of obligation to shift electricity in 1977 use was marginally dependent on other beliefs. By 1979, these variables were completely supplanted by the subjects' self-perception of their shifting behavior. While cognitive variables are important in the initial formation of a personal obligation to engage in shifting electricity use, the perpetuation of a feeling of obligation to shift over a period of years depends on perception of how often electricity shifting was undertaken and how much electricity had been shifted from on- to off-peak times.

24 CFR 206.131 - Contract rights and obligations for mortgages on individual dwelling units in a condominium.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Contract rights and obligations for... MORTGAGE INSURANCE Contract Rights and Obligations Condominiums § 206.131 Contract rights and obligations...] Termination of Insurance Contract ...

Obligation de reclassement et obligation de sécurité : quelle articulation en matière de santé au travail ? Obligation for reclassification and obligation for safety: what is the link in occupational health and safety? Obligación de reclasificación y obligación de seguridad : qué articulación en materia de salud laboral ?

Directory of Open Access Journals (Sweden)

Isabelle Desbarats

2010-05-01

Full Text Available Dans un contexte marqué par le souci croissant de protéger la santé des travailleurs ainsi que leur emploi, on observe que deux obligations patronales - de sécurité et de reclassement - jouent, en Droit Français, un rôle majeur dans la construction d’un droit à la sécurité au travail comme dans celle d’un droit de l’emploi. Certes, il est vrai qu’opérer un rapprochement entre ces deux obligations semble hasardeux, tant leur domaine et leur logique paraissent différents. Pour autant, un tel rapprochement est, non seulement possible, mais vraisemblablement fructueux : possible en premier lieu, car ces deux obligations ont en commun le fait d’entraîner une restriction du pouvoir patronal de direction ; enrichissant également parce que tout porte à croire que l’obligation de reclassement peut - voire doit - s’analyser comme le prolongement de l’obligation de sécurité.In a context marked by increasing concern to protect the health of workers as well as their employment, it is observed that two employers’ obligations—safety and reclassification—play, in French law, a major role in the construction of a right to safety in the workplace and a right to employment. Actually, a comparison of these two obligations seems hazardous, because their field and logic appear to be different. However, such a connection is not only possible, but probably beneficial : possible first, because these two obligations both involve a restriction of the employers’ management power, and also beneficial because everything leads to the belief that the obligation of reclassification can—and even must—be considered as an extension of the obligation of safety.En un contexto marcado por la constante preocupación de proteger la salud de los trabajadores y su empleo, se observa que dos obligaciones patronales- aquella de seguridad y aquella de reclasificación- desempeñan, en el derecho francés, un papel importante en la construcci

Life-Long Learning and Social Responsibility Obligations

Science.gov (United States)

Mayes, Robin

2013-01-01

The literature affirms that widespread lapses in corporate social responsibility obligations (unethical behaviors) have periodically brought about extensive forfeitures of economic wealth and countless job losses leaving the world economy in recession or depression. Put forth as a resolution to unemployment issues the academic literature champions…

Obligation of information and nuclear medicine after the law of march 4. 2002; Obligation d'information en medecine nucleaire apres la loi du 4 mars 2002

Energy Technology Data Exchange (ETDEWEB)

Bloch, L. [Universite Montesquieu, ATER, 33 - Bordeaux (France)

2002-06-01

The default of the obligation of information, which should only be a deontological fault, had begun to intrude on the area of responsibility, whether it be criminal or indeed civil. 'Ethical' responsibility took over a 'technical' responsibility limited by the primacy of fault. The law of March 4, 2002 prepared the ground for a return of this sword of Damocles towards its natural area, that is to say deontological fault which comes within ordinal jurisdictions. Thus the main contribution of this law is to be found in the definition of medical responsibility which, by limiting responsibility to a technical fault, seems to rule out the default of the obligation of information. The law of March 4, 2002 has not stirred up the content of the obligation of information for all that. The question of the information on exceptional risks is the only one to have noticeably evolved, since information now concerns only predictable risks. Therefore, the law of March 4, 2002, in no way leads to the death of the obligation of information, quite the reverse: the quality requirements in the information of the patient are even reinforced in some of their aspects, but in compensation for these requirements, there is no exacerbated responsibility anymore. (author)

Law and Behaviours in Social Dilemmas : Testing the Effect of Obligations on Cooperation

NARCIS (Netherlands)

Galbiati, R.; Vertova, P.

2005-01-01

Laws consist of two components: the 'obligations' they express and the 'incentives' designed to enforce them.In this paper we run a public good experiment to test whether or not obligations have any independent effect on cooperation in social dilemmas.The results show that, for given marginal

Epidemiology and antimicrobial susceptibilities of wound isolates of obligate anaerobes from combat casualties.

Science.gov (United States)

White, Brian K; Mende, Katrin; Weintrob, Amy C; Beckius, Miriam L; Zera, Wendy C; Lu, Dan; Bradley, William; Tribble, David R; Schnaubelt, Elizabeth R; Murray, Clinton K

2016-02-01

Data from recent conflicts related to war wounds and obligate anaerobes are limited. We define the epidemiology and antimicrobial susceptibility of obligate anaerobes from Iraq and Afghanistan casualties (6/2009-12/2013), as well as their association with clinical outcomes. Susceptibility against eleven antibiotics (7 classes) was tested. Overall, 59 patients had 119 obligate anaerobes identified (83 were first isolates). Obligate anaerobes were isolated 7-13 days post-injury, primarily from lower extremity wounds (43%), and were largely Bacteroides spp. (42%) and Clostridium spp. (19%). Patients with pelvic wounds were more likely to have Bacteroides spp. and concomitant resistant gram-negative aerobes. Seventy-three percent of isolates were resistant to ≥1 antimicrobials. Bacteroides spp. demonstrated the most resistance (16% of first isolates). Patients with resistant isolates had similar outcomes to those with susceptible strains. Serial recovery of isolates occurred in 15% of patients and was significantly associated with isolation of Bacteroides spp., along with resistant gram-negative aerobes. Published by Elsevier Inc.

Mothers', fathers' and children's perceptions of parents' expectations about children's family obligations in nine countries.

Science.gov (United States)

Lansford, Jennifer E; Godwin, Jennifer; Alampay, Liane Peña; Uribe Tirado, Liliana Maria; Zelli, Arnaldo; Al-Hassan, Suha M; Bacchini, Dario; Bombi, Anna Silvia; Bornstein, Marc H; Chang, Lei; Deater-Deckard, Kirby; Di Giunta, Laura; Dodge, Kenneth A; Malone, Patrick S; Oburu, Paul; Pastorelli, Concetta; Skinner, Ann T; Sorbring, Emma; Tapanya, Sombat

2016-10-01

Children's family obligations involve assistance and respect that children are expected to provide to immediate and extended family members and reflect beliefs related to family life that may differ across cultural groups. Mothers, fathers and children (N = 1432 families) in 13 cultural groups in 9 countries (China, Colombia, Italy, Jordan, Kenya, Philippines, Sweden, Thailand and United States) reported on their expectations regarding children's family obligations and parenting attitudes and behaviours. Within families, mothers and fathers had more concordant expectations regarding children's family obligations than did parents and children. Parenting behaviours that were warmer, less neglectful and more controlling as well as parenting attitudes that were more authoritarian were related to higher expectations regarding children's family obligations between families within cultures as well as between cultures. These international findings advance understanding of children's family obligations by contextualising them both within families and across a number of diverse cultural groups in 9 countries. © 2015 International Union of Psychological Science.

22 CFR 231.07 - Fiscal Agent obligations.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Fiscal Agent obligations. 231.07 Section 231.07 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

The pipeline service obligation under changing LDC purchasing practices

International Nuclear Information System (INIS)

Neff, S.J.

1990-01-01

Historically, interstate natural gas pipelines served as aggregators and transporters of gas supplies from the producing fields to the city-gate. In turn, local distribution companies (LDCs) bought gas from pipelines at the city-gate under long-term sales contracts and resold the gas to retail customers. Once a pipeline/LDC sales relationship was established through a regulated certificate process, the LDC was assured of gas supply up to the level of its contract demand (CD) at just and reasonable rates until abandonment of the pipeline's sales service obligation was granted by the Federal Energy Regulatory Commission (FERC). During the years of regulated wellhead pricing and limited gas deliverability, pipelines signed long-term take-or-pay contracts with producers to induce them to develop and commit new gas supplies. Those supply cost obligations were reflected in tariff minimum bill provisions. For years, this pipeline/LDC arrangement was mutually beneficial and provided assured firm service. With the load diversity on large interstate pipeline systems and the make-up provisions under take-or-pay clauses, these gas purchase contracts provided supply reliability without negative economic consequence to the pipelines. Then, with the issuance of FERC Order Nos. 380, 436, and 500, LDCs' obligations to purchase gas from pipeline suppliers according to the terms of those long term sales agreements were irrevocably altered. The impacts of those long term sales agreements were irrevocably altered. The impacts of those orders the elimination of minimum bills and the advent of open access transportation caused a serious erosion of the mutual obligations between pipelines and their LDC customers. The result has been a significant loss of pipeline sales markets as LDC customers have chosen alternative supplied, often at the urging of state public utility commissions (PUCs) to lower short-term costs

Newcomer Psychological Contracts and Employee Socialization Activities: Does Perceived Balance in Obligations Matter?

Science.gov (United States)

Payne, Stephanie C.; Culbertson, Satoris S.; Boswell, Wendy R.; Barger, Eric J.

2008-01-01

We sought to determine the extent to which one's beliefs about the relationship between an employee and an organization at the start of employment influence subsequent socialization activities. The balance of employee exchange relationships, employee perceptions of both their own obligations and the employers' obligations, were collected from 120…

13 CFR 500.213 - Termination of obligations.

Science.gov (United States)

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Termination of obligations. 500.213 Section 500.213 Business Credit and Assistance EMERGENCY OIL AND GAS GUARANTEED LOAN BOARD... the Application, the Guarantee or the Loan Documents; (5) A Lender fails to make a demand for payment...

Modeling and analysis of renewable energy obligations and technology bandings in the UK electricity market

International Nuclear Information System (INIS)

Gürkan, Gül; Langestraat, Romeo

2014-01-01

In the UK electricity market, generators are obliged to produce part of their electricity with renewable energy resources in accordance with the Renewable Obligation Order. Since 2009 technology banding has been added, meaning that different technologies are rewarded with a different number of certificates. We analyze these two different renewable obligation policies in a mathematical representation of an electricity market with random availabilities of renewable generation outputs and random electricity demand. We also present another, alternative, banding policy. We provide revenue adequate pricing schemes for the three obligation policies. We carry out a simulation study via sampling. A key finding is that the UK banding policy cannot guarantee that the original obligation target is met, hence potentially resulting in more pollution. Our alternative provides a way to make sure that the target is met while supporting less established technologies, but it comes with a significantly higher consumer price. Furthermore, as an undesirable side effect, we observe that a cost reduction in a technology with a high banding (namely offshore wind) leads to more CO 2 emissions under the UK banding policy and to higher consumer prices under the alternative banding policy. - Highlights: • We model and analyze three renewable obligation policies in a mathematical framework. • We provide revenue adequate pricing schemes for the three policies. • We carry out a simulation study via sampling. • The UK policy cannot guarantee that the original obligation target is met. • Cost reductions can lead to more pollution or higher prices under banding policies

UK ignores treaty obligations

International Nuclear Information System (INIS)

Roche, P.

1995-01-01

A detailed critique is offered of United Kingdom (UK) political policy with respect to the Non-Proliferation Treaty, an interim agreement valid while nuclear disarmament was supposed to occur, by a representative of Greenpeace, the anti-nuclear campaigning group. The author argues that the civil and military nuclear programmes are still firmly linked, and emphasises his opinions by quoting examples of how UK politicians have broken treaty obligations in order to pursue their own political, and in some cases financial, goals. It is argued that the treaty has failed to force nuclear countries to disarm because of its promoted civil nuclear power programmes. (U.K.)

12 CFR 987.5 - Obligations of the Banks and the Office of Finance; no Adverse Claims.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Obligations of the Banks and the Office of Finance; no Adverse Claims. 987.5 Section 987.5 Banks and Banking FEDERAL HOUSING FINANCE BOARD OFFICE OF FINANCE BOOK-ENTRY PROCEDURE FOR CONSOLIDATED OBLIGATIONS § 987.5 Obligations of the Banks and the Office of Finance; no Adverse Claims. (a) Except...

Obligations to power supply and Antitrust Law of the European Community; Strombezugsverpflichtungen und EG-Kartellverbot

Energy Technology Data Exchange (ETDEWEB)

Lerch, Dirk

2008-07-01

In the European electricity supply industry, a change to competition-oriented national markets under development of a common European electricity market is observed for some years. Under this aspect, the author of the contribution under consideration reports on obligations to the current power supply and on the trust prohibition in the European Community. The contribution under consideration consists of the following three chapters: (a) Discussion of fundamental questions regarding to cartel legal evaluation of obligations to power supply; (b) Conditions of the art. 81 sect. 1 EEC and application to obligations for power supply; (c) Exemption from the obligation to power supply according to art. 1 sect. 3 EEC. In particular, the regulation of the group exemption for vertical agreements of 22nd December, 1999, is considered.

Resolving Conflicts between Beliefs, Obligations, Intentions, and Desires

NARCIS (Netherlands)

Broersen, J.M.; Dastani, M.M.; Torre, L. van der

2001-01-01

This paper provides a logical analysis of conflicts between informational, motivational and deliberative attitudes such as beliefs, obligations, intentions, and desires. The contributions are twofold. First, conflict resolutions are classi ed based on agent types, and formalized in an extension

Collateralised loan obligations (CLOs): A primer

OpenAIRE

Jobst, Andreas A.

2002-01-01

The following descriptive paper surveys the various types of loan securitisation and provides a working definition of so-called collateralised loan obligations (CLOs). Free of the common rhetoric and slogans, which sometimes substitute for understanding of the complex nature of structured finance, this paper describes the theoretical foundations of this specialised form of loan securitisation. Not only the distinctive properties of CLOs, but also the information economics inherent in the tran...

Electricity generation sectors under purchase obligation: support arrangement analysis

International Nuclear Information System (INIS)

2013-04-01

This report aims at assessing the operation of the support arrangement by which currently benefit some electricity production sectors in France (renewable energies, co-generation) with respect to the evolution of the energy mix within the frame of energy transition. Other support arrangements presently adopted in Europe are also addressed as lessons to be learned. Criteria are established for any support arrangement. The report presents the French and European context regarding such support arrangement with purchasing obligation, and addresses the future evolutions of the European Commission. It highlights challenges for the electric system and for the energy market (impact on investments, optimization of market operation), describes and assesses the French purchasing obligation arrangement, and describes and assesses other existing support arrangements

NSF Obligations for Top 200 Institutions by Fiscal Year

Data.gov (United States)

National Science Foundation — An text/xml file containing FY 2001 through FY 2015 National Science Foundation (NSF) obligations by institution for the top 200 recipients defined in terms of total...

Conditions applying to Australian uranium exports - safeguards obligations under NPT

International Nuclear Information System (INIS)

Rotsey, W.B.

1975-08-01

The Australian Government's expressed desire to inhibit the spread of nuclear weapons and its wish to prevent Australia's uranium exports being used for manufacture of nuclear explosives are underwritten by Australia's formal international obligations. Australia is not free to export its material without paying due regard to supra-national requirements. This paper defines two safeguards regimes, one applying to countries such as Australia which are party to the Treaty on Non-Proliferation of Nuclear Weapons (NPT), the other to those which are not parties. The application of safeguards and the role of the International Atomic Energy Agency (IAEA) are briefly explained. Australia's obligations under the NPT and those stemming from specific undertakings to the IAEA are stated. The latter require Australia to ensure that Non-Nuclear Weapons States not party to the NPT give assurances that Australian uranium will not be used for the manufacture of nuclear explosives and that they will permit verification by the IAEA. These obligations give rise to a set of minimum conditions applying to exports of Australian uranium which vary according to the NPT status of the importing countries. (author)

Kant's assessment of motivation in the fulfillment of social obligations.

Science.gov (United States)

Knupp, Jackie

2006-01-01

This paper explores the motivations of physicians who promote the health of their communities through the fulfillment of social obligations beyond the boundaries of their own patients. Based on the assumption that physicians do not have social obligations, this paper looks at the normative, motivational question, namely "How should physicians be motivated to fulfill social obligations?" The paper traces the Kantian view of morality and motivation. The distinctions between required, merely permissible, and forbidden actions is drawn. Furthermore, Kant's view that required actions done in accordance with duty are of no moral worth is critiqued from three stand points. First, it is argued that just because motivations outside of Kantian-based duty are not as good, it does not follow that these motivations are of no moral worth. Second, it is argued that there are some motivations behind required actions that are clearly better than other motivations. Third, it is argued that required actions done in accordance with duty are clearly better than those actions done without relevance to duty. The paper concludes that many required actions done in accordance with duty are performed from motivations that do have moral worth.

24 CFR 236.755 - Housing owner's obligation under contract to report tenant income increase.

Science.gov (United States)

2010-04-01

... FOR RENTAL PROJECTS Rental Assistance Payments § 236.755 Housing owner's obligation under contract to... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Housing owner's obligation under contract to report tenant income increase. 236.755 Section 236.755 Housing and Urban Development...

Specific prisoners' rights and their obligations as forms of human rights restrictions

Directory of Open Access Journals (Sweden)

В. О. Човган

2014-12-01

Full Text Available This article examines such forms of restrictions on rights of prisoners as an obligation and a specific subjective right. Examples of how these forms of restrictions may appear in legislation are disclosed. It is shown that obligations of prisoners should be always considered as restriction of prisoners' rights. The cases in which a specific right can be recognized as a form of restriction on rights of prisoners are described.

41 CFR 102-75.950 - Who has the responsibility for paying property-related obligations pending transfer or disposal...

Science.gov (United States)

2010-07-01

... responsibility for paying property-related obligations pending transfer or disposal of the property? 102-75.950... property-related obligations pending transfer or disposal of the property? Except as otherwise provided in... or other property-related obligations pending transfer or disposal of the property. Decontamination ...

Obama states obligation to act on climate change

Science.gov (United States)

Showstack, Randy

2012-11-01

Obama states obligation to act on climate change Noting increased global temperatures, Arctic ice melt, and severe weather events, President Barack Obama said that climate change is real and called for a conversation across the country to determine what can be done about it.

Obligation for renewable electricity in the Netherlands. Outline of options and preconditions

International Nuclear Information System (INIS)

Van Tilburg, X.; Jansen, J.C.; Uyterlinde, M.A.; Lensink, S.M.

2006-12-01

In August 2006, the MEP feed-in system was suspended to prevent excess budget claims while the 2010 target is expected to be met. A number of politicians suggest the time is right to change the feed-in system to an obligation scheme. On assignment of the Dutch Ministry of Economic Affairs ECN has reviewed whether The Netherlands could be ready for a successful introduction of an obligation-based support scheme for renewable electricity in the Netherlands. This report is not a detailed study, but offers a survey of possibilities and preconditions. The question whether The Netherlands is ready for a successful introduction can be yes only when two conditions are met. Firstly, the government has to pursue a strategy of long term policy stability, essential for establishing a favourable investment climate. Secondly, a certificate market has to be set up that is able to function properly and efficiently (i.e. sufficient market liquidity). Excessive producers' surplus, under certain circumstances a side effect of an obligation based system, may be reduced using a hybrid approach combining direct subsidies and a quota obligation. This report describes that careful planning is required and hence a possible switch cannot be implemented before 2009 or 2010. The government plays an important role in establishing a.positive and stable investment climate. At the introduction of an obligation based scheme, the government should present an ambitious and broadly supported long term target. Commitment to maintain the obligation for at least fifteen to twenty years ahead is of key importance. In addition to a stable investment climate, it is also important to have a sufficiently transparent and liquid market for tradable green certificates. Whether this is achievable in the Netherlands remains open to investigation. The government has limited means at its disposal for providing sufficient market efficiency. Harmonisation of support schemes at the EU level is not to be expected in

Arcobacter halophilus sp nov., the first obligate halophile in the genus Arcobacter

DEFF Research Database (Denmark)

Donachie, S.P.; Bowman, J.P.; On, Stephen L.W.

2005-01-01

. Most notably, LA31B(T) was found to be an obligate halophile, a hitherto undescribed feature among recognized Arcobacter species. These data indicate that LA31B(T) should be considered to represent a novel species in the genus Arcobacter, for which the name Arcobacter halophilus sp. nov. is proposed....... This is the first obligately halophilic member of the genus. The type strain is LA31B(T) (= ATCC BAA- 102 2 T=CIP 108450(T))....

22 CFR 211.5 - Obligations of cooperating sponsor.

Science.gov (United States)

2010-04-01

... USE IN DISASTER RELIEF, ECONOMIC DEVELOPMENT AND OTHER ASSISTANCE § 211.5 Obligations of cooperating... of books and records maintained by recipient agencies that receive monetized proceeds and/or program..., reported and accounted for as provided in this Regulation, with special reference to paragraphs (k) and (l...

31 CFR 223.18 - Performance of agency obligations.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Performance of agency obligations. 223.18 Section 223.18 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE SURETY COMPANIES DOING BUSINESS...

31 CFR 203.6 - Obligations of TT&L depositaries.

Science.gov (United States)

2010-07-01

... TREASURY TAX AND LOAN PROGRAM General Information § 203.6 Obligations of TT&L depositaries. A TT&L depositary must: (a) Administer a TIP main account balance, SDI account balance, or TIO account balance, as...

The Bali Firewall and Member States’ Future Obligations within the Climate Change Regime

Directory of Open Access Journals (Sweden)

Christopher Smith

2010-12-01

Full Text Available At the 13th Conference of the Parties to the United Nations Framework Convention on Climate Change, held in Bali in 2007, the COP decided to launch a process to reach an agreed outcome at its 15th session held in Copenhagen in 2009. This decision, known as the Bali Action Plan, contains two subparagraphs that set out broadly the parameters within which future possible legal obligations pertaining to developed and developing nations regarding the mitigation of climate change are to be addressed as part of this process as per the decision. The purpose of addressing these obligations is to enable the implementation of the Convention, so the subparagraphs should have a basis in the Convention. One subparagraph deals with future possible legal obligations pertaining to developed country Parties and the other deals with those pertaining to developing country Parties. The content of each subparagraph differs and therefore a fundamental difference in the future possible legal obligations pertaining to developed and developing country Parties is pre-defined within the Bali Action Plan. This difference, as it is perceived by most developing country Parties, has become known colloquially as the Bali firewall. This article will set out the content of the pre-defined sets of parameters and investigate the basis for this content, and difference in content in relation to the other, in the provisions and principles set out in the Convention. It will then conclude on the validity of the Bali firewall in terms of the content of the Convention. Additionally it will analyse whether the ‘outcome’ of the 15th Conference of the Parties falls in line with the future legal obligations of member states within the climate regime as perceived by most developing country Parties in terms of the Bali firewall. Lastly it will analyse member states’ future legal obligations within the climate change regime in the context of the overall objective of the Convention and the

12 CFR 611.1270 - Repayment of obligations-terminating bank.

Science.gov (United States)

2010-01-01

...-wide obligations in a method that we deem acceptable. Before we make a final decision on your proposal... respect to financing and disclosure. (2) If you and the other Farm Credit banks are unable to reach...

Motivation Counts: Autonomous But Not Obligated Sharing Promotes Happiness in Preschoolers.

Science.gov (United States)

Wu, Zhen; Zhang, Zhen; Guo, Rui; Gros-Louis, Julie

2017-01-01

Research has demonstrated that prosocial sharing is emotionally rewarding, which leads to further prosocial actions; such a positive feedback loop suggests a proximal mechanism of human's tendency to act prosocially. However, it leaves open a question as to how the emotional benefits from sharing develop in young children and whether sharing under pressure promotes happiness as well. The current study directly compared 3- and 5-year-old Chinese children's happiness when sharing was autonomous (the recipient did not contribute to getting the reward) with when sharing was obligated (the recipient and the actor jointly earned the reward). We found that children shared more items overall when sharing was obligated than autonomous, demonstrating their conformity to social norms of merit-based sharing. In children who eventually shared with others, 5-year-olds gave out more stickers in the obligated sharing condition than in the autonomous sharing condition, but 3-year-olds shared the same amount between the conditions, suggesting that 5-year-olds adhered to the merit-based sharing norm more strictly than 3-year-olds. Moreover, in the autonomous sharing condition, children displayed greater happiness when they shared with the recipient than when they kept stickers for themselves, suggesting that costly prosocial giving benefited children with positive mood; however, children did not gain happiness when they shared with the recipient in the obligated sharing condition. These findings demonstrate that children's affective benefits depend on the motivation underlying their prosocial behavior, and further imply that normative force and emotional gains may independently drive preschoolers' prosocial behaviors.

Motivation Counts: Autonomous But Not Obligated Sharing Promotes Happiness in Preschoolers

Directory of Open Access Journals (Sweden)

Zhen Wu

2017-05-01

Full Text Available Research has demonstrated that prosocial sharing is emotionally rewarding, which leads to further prosocial actions; such a positive feedback loop suggests a proximal mechanism of human’s tendency to act prosocially. However, it leaves open a question as to how the emotional benefits from sharing develop in young children and whether sharing under pressure promotes happiness as well. The current study directly compared 3- and 5-year-old Chinese children’s happiness when sharing was autonomous (the recipient did not contribute to getting the reward with when sharing was obligated (the recipient and the actor jointly earned the reward. We found that children shared more items overall when sharing was obligated than autonomous, demonstrating their conformity to social norms of merit-based sharing. In children who eventually shared with others, 5-year-olds gave out more stickers in the obligated sharing condition than in the autonomous sharing condition, but 3-year-olds shared the same amount between the conditions, suggesting that 5-year-olds adhered to the merit-based sharing norm more strictly than 3-year-olds. Moreover, in the autonomous sharing condition, children displayed greater happiness when they shared with the recipient than when they kept stickers for themselves, suggesting that costly prosocial giving benefited children with positive mood; however, children did not gain happiness when they shared with the recipient in the obligated sharing condition. These findings demonstrate that children’s affective benefits depend on the motivation underlying their prosocial behavior, and further imply that normative force and emotional gains may independently drive preschoolers’ prosocial behaviors.

Modeling and analysis of renewable energy obligations and technology bandings in the UK electricity market

NARCIS (Netherlands)

Gurkan, G.; Langestraat, R.

In the UK electricity market, generators are obliged to produce part of their electricity with renewable energy resources in accordance with the Renewable Obligation Order. Since 2009 technology banding has been added, meaning that different technologies are rewarded with a different number of

14 CFR 272.8 - Obligation to continue service.

Science.gov (United States)

2010-01-01

... PROCEEDINGS) ECONOMIC REGULATIONS ESSENTIAL AIR SERVICE TO THE FREELY ASSOCIATED STATES § 272.8 Obligation to... eligible Freely Associated State place below the level of essential air service to such place, whether or not the Department has previously determined the level of essential air service to such place, the...

Short communications : Are wild African lungfish obligate air ...

African Journals Online (AJOL)

Laboratory studies have resulted in classification of the marbled African lungfish, Protopterus aethiopicus, as an obligate air-breather. However, there have been no investigations of the extent of dependence on aerial respiration by this species in the wild. We used radio telemetry to obtain quantitative information on the ...

The Obligation to Provide Free Basic Education in South Africa: An International Law Perspective

Directory of Open Access Journals (Sweden)

L Arendse

2011-10-01

Full Text Available In South Africa many learners are denied the right to basic education because of the levying of school fees and other educational charges, in spite of the international obligation imposed on government to provide free primary education. This article examines the exact nature and extent of this obligation by exploring the concept of "free" basic education. The applicable international instruments and their interpretation as well as the significance of the right to education as a central, facilitative right are examined in order to establish the content of the right to basic education and the legal obligations that ensue. Against this background, the implications of the South African Constitutional Court's approach to the realisation of socio-economic rights and the possibility of the establishment of a core minimum obligation are analysed. It is argued that learners in South Africa may come from different socio-economic backgrounds but as learners in the same public school domain and as equal bearers of their constitutional right to basic education all of them are entitled to the same type and quality of free basic education.

Social physique anxiety, obligation to exercise, and exercise choices among college students.

Science.gov (United States)

Chu, Hui-Wen; Bushman, Barbara A; Woodard, Rebecca J

2008-01-01

The authors examined relationships among social physique anxiety, obligation to exercise, and exercise choices. College students (N = 337; 200 women, 137 men) volunteered to complete 3 questionnaires: the Social Physique Anxiety Scale (SPAS), Obligatory Exercise Questionnaire (OEQ), and Physical Activity Specification Survey (PASS). On the SPAS, men (M score = 31.9 +/- 8.8) differed from women (M score = 37.3 +/- 8.3; p = .001). Men (M score = 43.0 +/- 9.9) and women (M score = 43.0 +/- 9.6) responded similarly (p = .94) on the OEQ. There was no interaction between sex and exercise level on the SPAS or OEQ. When separated by low, medium, and high SPAS scores, neither OEQ nor exercise scores differed. Obligation to exercise appears to be similar for both sexes. Women, however, appear to have higher levels of anxiety regarding how others evaluate their physique than do men. The combination of level of activity and sex do not appear to be associated with social physique anxiety or obligation to exercise.

Mothers’, Fathers’, and Children’s Perceptions of Parents’ Expectations about Children’s Family Obligations in Nine Countries

Science.gov (United States)

Lansford, Jennifer E.; Godwin, Jennifer; Alampay, Liane Peña; Tirado, Liliana Maria Uribe; Zelli, Arnaldo; Al-Hassan, Suha M.; Bacchini, Dario; Bombi, Anna Silvia; Bornstein, Marc H.; Chang, Lei; Deater-Deckard, Kirby; Di Giunta, Laura; Dodge, Kenneth A.; Malone, Patrick S.; Oburu, Paul; Pastorelli, Concetta; Skinner, Ann T.; Sorbring, Emma; Tapanya, Sombat

2016-01-01

Children’s family obligations involve assistance and respect that children are expected to provide to immediate and extended family members and reflect beliefs related to family life that may differ across cultural groups. Mothers, fathers, and children (N = 1,432 families) in 13 cultural groups in nine countries (China, Colombia, Italy, Jordan, Kenya, Philippines, Sweden, Thailand, and United States) reported on their expectations regarding children’s family obligations and parenting attitudes and behaviors. Within families, mothers and fathers had more concordant expectations regarding children’s family obligations than did parents and children. Parenting behaviors that were warmer, less neglectful, and more controlling as well as parenting attitudes that were more authoritarian were related to higher expectations regarding children’s family obligations between families within cultures as well as between cultures. These international findings advance understanding of children’s family obligations by contextualizing them both within families and across a number of diverse cultural groups in nine countries. PMID:26104262

34 CFR 76.707 - When obligations are made.

Science.gov (United States)

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false When obligations are made. 76.707 Section 76.707 Education Office of the Secretary, Department of Education STATE-ADMINISTERED PROGRAMS What Are the... subgrantee receives the services. (f) Travel When the travel is taken. (g) Rental of real or personal...

Genetic Information, the Principle of Rescue, and Special Obligations.

Science.gov (United States)

Liao, S Matthew; Mackenzie, Jordan

2018-05-01

In "Genetic Privacy, Disease Prevention, and the Principle of Rescue," Madison Kilbride argues that patients have a duty to warn biological family members about clinically actionable adverse genetic findings. The duty does not stem from the special obligations that we may have to family members, she argues, but rather follows from the principle of rescue, which she understands as the idea that one ought to prevent, reduce, or mitigate the risk of harm to another person when the expected harm is serious and the cost or risk to oneself is sufficiently moderate. We doubt, however, whether the principle of rescue can ground a duty to warn in the cases Kilbride envisages, and we suggest that Kilbride may have underappreciated the role that special obligations could play in generating a duty to warn family members. © 2018 The Hastings Center.

45 CFR 660.5 - What is the Director's obligation with respect to Federal interagency coordination?

Science.gov (United States)

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false What is the Director's obligation with respect to... Welfare (Continued) NATIONAL SCIENCE FOUNDATION INTERGOVERNMENTAL REVIEW OF THE NATIONAL SCIENCE FOUNDATION PROGRAMS AND ACTIVITIES § 660.5 What is the Director's obligation with respect to Federal...

Obligation of information and nuclear medicine after the law of march 4. 2002

International Nuclear Information System (INIS)

Bloch, L.

2002-01-01

The default of the obligation of information, which should only be a deontological fault, had begun to intrude on the area of responsibility, whether it be criminal or indeed civil. 'Ethical' responsibility took over a 'technical' responsibility limited by the primacy of fault. The law of March 4, 2002 prepared the ground for a return of this sword of Damocles towards its natural area, that is to say deontological fault which comes within ordinal jurisdictions. Thus the main contribution of this law is to be found in the definition of medical responsibility which, by limiting responsibility to a technical fault, seems to rule out the default of the obligation of information. The law of March 4, 2002 has not stirred up the content of the obligation of information for all that. The question of the information on exceptional risks is the only one to have noticeably evolved, since information now concerns only predictable risks. Therefore, the law of March 4, 2002, in no way leads to the death of the obligation of information, quite the reverse: the quality requirements in the information of the patient are even reinforced in some of their aspects, but in compensation for these requirements, there is no exacerbated responsibility anymore. (author)

Understanding how commensal obligate anaerobic bacteria regulate immune functions in the large intestine.

Science.gov (United States)

Maier, Eva; Anderson, Rachel C; Roy, Nicole C

2014-12-24

The human gastrointestinal tract is colonised by trillions of commensal bacteria, most of which are obligate anaerobes residing in the large intestine. Appropriate bacterial colonisation is generally known to be critical for human health. In particular, the development and function of the immune system depends on microbial colonisation, and a regulated cross-talk between commensal bacteria, intestinal epithelial cells and immune cells is required to maintain mucosal immune homeostasis. This homeostasis is disturbed in various inflammatory disorders, such as inflammatory bowel diseases. Several in vitro and in vivo studies indicate a role for Faecalibacterium prausnitzii, Bacteroides thetaiotaomicron, Bacteroides fragilis, Akkermansia muciniphila and segmented filamentous bacteria in maintaining intestinal immune homeostasis. These obligate anaerobes are abundant in the healthy intestine but reduced in several inflammatory diseases, suggesting an association with protective effects on human health. However, knowledge of the mechanisms underlying the effects of obligate anaerobic intestinal bacteria remains limited, in part due to the difficulty of co-culturing obligate anaerobes together with oxygen-requiring human epithelial cells. By using novel dual-environment co-culture models, it will be possible to investigate the effects of the unstudied majority of intestinal microorganisms on the human epithelia. This knowledge will provide opportunities for improving human health and reducing the risk of inflammatory diseases.

Understanding How Commensal Obligate Anaerobic Bacteria Regulate Immune Functions in the Large Intestine

Science.gov (United States)

Maier, Eva; Anderson, Rachel C.; Roy, Nicole C.

2014-01-01

The human gastrointestinal tract is colonised by trillions of commensal bacteria, most of which are obligate anaerobes residing in the large intestine. Appropriate bacterial colonisation is generally known to be critical for human health. In particular, the development and function of the immune system depends on microbial colonisation, and a regulated cross-talk between commensal bacteria, intestinal epithelial cells and immune cells is required to maintain mucosal immune homeostasis. This homeostasis is disturbed in various inflammatory disorders, such as inflammatory bowel diseases. Several in vitro and in vivo studies indicate a role for Faecalibacterium prausnitzii, Bacteroides thetaiotaomicron, Bacteroides fragilis, Akkermansia muciniphila and segmented filamentous bacteria in maintaining intestinal immune homeostasis. These obligate anaerobes are abundant in the healthy intestine but reduced in several inflammatory diseases, suggesting an association with protective effects on human health. However, knowledge of the mechanisms underlying the effects of obligate anaerobic intestinal bacteria remains limited, in part due to the difficulty of co-culturing obligate anaerobes together with oxygen-requiring human epithelial cells. By using novel dual-environment co-culture models, it will be possible to investigate the effects of the unstudied majority of intestinal microorganisms on the human epithelia. This knowledge will provide opportunities for improving human health and reducing the risk of inflammatory diseases. PMID:25545102

34 CFR 75.707 - When obligations are made.

Science.gov (United States)

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false When obligations are made. 75.707 Section 75.707 Education Office of the Secretary, Department of Education DIRECT GRANT PROGRAMS What Are the Administrative... services. (f) Travel When the travel is taken. (g) Rental of real or personal property When the grantee...

Family Obligations in Micronesian Cultures: Implications for Educators

Science.gov (United States)

Ratliffe, Katherine T.

2010-01-01

Micronesian people, a new group of immigrants to the USA, have a strong system of responsibilities to family members that guides their priorities and actions. When family obligations clash with school priorities, conflicts can occur. I interviewed 26 adults to learn about the relationships and responsibilities of family members to each other in…

\\"Forgotten\\" Humanitarian Obligations: The case of the Saharawi ...

African Journals Online (AJOL)

... lay at the bar of international justice to call the international community to account for failures of performance on humanitarian obligations. It is their case that I take up here, as a problem of ethics in international affairs, as the minimum of a philosopher's recompense owed this people today. African Studies Monograph Vol.

Filial obligations today : moral practice, perception and ethical theory

NARCIS (Netherlands)

Stuifbergen, M.C.

2011-01-01

This thesis is about the meaning of filial obligations in Dutch society today. The thesis consists of a general introduction, two quantitative sociological studies, two qualitative studies, an ethical analysis and a general discussion. In the introduction, the background for the research questions

25 CFR 226.9 - Rental and drilling obligations.

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Rental and drilling obligations. 226.9 Section 226.9... RESERVATION LANDS FOR OIL AND GAS MINING Leasing Procedure, Rental and Royalty § 226.9 Rental and drilling... in the lease terms, or 12 months from the date the Superintendent consents to drilling on any...

Molecular genetic studies on obligate anaerobic bacteria

International Nuclear Information System (INIS)

Woods, D.R.

1982-01-01

Molecular genetic studies on obligate anaerobic bacteria have lagged behind similar studies in aerobes. However, the current interest in biotechnology, the involvement of anaerobes in disease and the emergence of antibioticresistant strains have focused attention on the genetics of anaerobes. This article reviews molecular genetic studies in Bacteroides spp., Clostridium spp. and methanogens. Certain genetic systems in some anaerobes differ from those in aerobes and illustrate the genetic diversity among bacteria

Coping with the Obligation Dilemma: Prototypes of Social Workers in the Nursing Home

OpenAIRE

Lev, Sagit; Ayalon, Liat

2015-01-01

We examined the ways in which the social worker is coping with obligation dilemma in an Israeli nursing home. The research was conducted using semi-structured, in-depth interviews carried out with fifteen social workers employed in nursing homes. The interviews were analysed thematically, using constant comparisons. The three themes were concerned with the social worker's place in the nursing home, her relationship with the management and staff, and her coping with the obligation dilemma. The...

Obligations, internalization, and excuse making: integrating the triangle model and self-determination theory.

Science.gov (United States)

Sheldon, Kennon M; Schachtman, Todd R

2007-04-01

Schlenker's triangle model (Schlenker, Britt, Pennington, Murphy, & Doherty, 1994, Schlenker, Pontari, & Christopher, 2001) identifies three excuses people use to avoid taking responsibility after failure: that one had no control in the situation, that the obligation was unclear, and that it was not really one's obligation. Three retrospective studies tested the presumed negative association between excuse making and responsibility taking. The studies also examined the effects of self-determination theory's concept of motivational internalization (Deci & Ryan, 2000) upon these variables. A complex but replicable pattern emerged, such that responsibility taking and motivational internalization correlated with adaptive outcomes such as future commitment and positive expectancy and excuse making did not. Of particular interest, perceiving that the person levying the obligation internalized motivation predicted responsibility taking, in all three studies. Implications for the triangle model, as well as for theories of maturity and personality development, are considered.

Protecting the Minor by Guardianship. Guardian’s Rights and Obligations and Parental Rights and Obligations. Comparative Aspects

OpenAIRE

Gavrilescu, Alin-Gheorghe

2010-01-01

The minor’s guardianship is a juridical institution by means of which the person called guardian provides the protection of the child’s person and patrimony, because the child does not have temporarily or irrevocably his parents’ protection or, in order to accomplish his interests, the child cannot be let in their care. As the content of protecting the minor by parents, the one of protecting him or her by guardianship is formed by a personal side, composed of the rights and the obligations ha...

Consequence in Law of the Original Contract Obligation in Case of Recovery of Losses Incurred by Nonfulfillment or Improper Fulfillment of the Contract

Directory of Open Access Journals (Sweden)

Popov I. V.

2012-11-01

Full Text Available The issue of the obligations structure concerning the breach of a contract is considered in the article. According to the author’s opinion there simultaneously exists the initial obligation in conformity with the contract and obligation of losses compensation for the contract breach. Such an approach allows to recover damages before the moment when the initial obligation is discontinued by law or by a contract provision. The correlation between the initial obligation and the obligation to compensate losses because of the contract breach is being analyzed here.

Fulfilment of administrative and professional organisational obligations and nurses' customer-oriented behaviours.

Science.gov (United States)

Trybou, Jeroen; Gemmel, Paul

2016-07-01

The aim of the study was to examine the relationship between the perceived quality of organisational exchange and nurses' customer-oriented behaviours. Hospitals face increasing competitive market conditions. Registered nurses interact closely with patients and therefore play an important front-office role towards patients. A cross-sectional study was conducted. Registered nurses (n = 151) of a Belgian hospital received a questionnaire to assess the fulfilment of administrative and professional organisational obligations and their customer-oriented behaviours. We found a positive relationship between psychological contract fulfilment and nurses' customer-oriented behaviours. More precisely administrative and professional psychological contract fulfilment relates significantly to nurses' service delivery and external representation. In case of internal influence only administrative psychological contract fulfilment was significantly related. Nurses' perceptions of the fulfilment of administrative and professional obligations are important to their customer-oriented behaviours. Nurse managers must be aware of the impact of fulfilling both administrative and professional obligations of registered nurses in order to optimise their customer-oriented behaviours. © 2016 John Wiley & Sons Ltd.

Ad hoc public disclosure obligations of public companies on the capital market

Directory of Open Access Journals (Sweden)

Marjanski Vladimir

2012-01-01

Full Text Available The author gives a comprehensive analysis of the obligations of public companies regarding the provision of periodical (ad hoc information to the public on the capital market. Ad hoc disclosure is to achieve a number of aims. It is one of the devices to secure the market's functional abilities. By means of regularly fulfilling this obligation, the market is provided with all the relevant information necessary to form adequate prices of market materials - i.e. securities and other financial instruments (the function of market protection. Investors are thus being able to aptly respond to modified circumstances and deliver investment decisions whether to buy or sell market materials the price of which are being changed (the function of investor protection. Due to the fact that the duty of ad hoc disclosure encompasses the obligation to reveal insider information directly affecting the emitter, ad hoc disclosure serves as a preventive measure, i.e. as a protection against illicit trade with insider information (the function of prevention against the abuse of insider information.

28 CFR 811.6 - Duration of the obligation to register.

Science.gov (United States)

2010-07-01

... section. (c) Reversal, vacation, or pardon. A person's obligation to register terminates if the person's conviction, finding of not guilty by reason of insanity, or finding that the person is a sexual psychopath is...

28 CFR 30.5 - What is the Attorney General's obligation with respect to Federal interagency coordination?

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false What is the Attorney General's obligation... the Attorney General's obligation with respect to Federal interagency coordination? The Attorney General, to the extent practicable, consults with and seeks advice from all other substantially affected...

34 CFR 686.43 - Obligation to repay the grant.

Science.gov (United States)

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false Obligation to repay the grant. 686.43 Section 686.43 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION TEACHER EDUCATION ASSISTANCE FOR COLLEGE AND HIGHER EDUCATION (TEACH...

15 CFR 711.4 - Assistance in determining your obligations.

Science.gov (United States)

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Assistance in determining your obligations. 711.4 Section 711.4 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS...

DEFINITION OF PUBLIC SERVICE OBLIGATION POTENTIAL IN THE NEW EU MEMBER STATES

Directory of Open Access Journals (Sweden)

Martin HROMÁDKA

2017-04-01

Full Text Available This paper deals with public service obligation, a form of state aid that applies to air services. The paper first provides general information on the European legislation applying to this form of state aid, and elaborates the legal framework and general principles. The second part is dedicated to a comparison of a similar subsidizing programme in the USA and Australia. An examination of current imposed public service obligation routes in Europe is provided in the following section. The coefficients defining the number of imposed PSO routes per various geo-economic variables have been defined.

A six-well plate method: less laborious and effective method for cultivation of obligate anaerobic microorganisms.

Science.gov (United States)

Nakamura, Kohei; Tamaki, Hideyuki; Kang, Myung Suk; Mochimaru, Hanako; Lee, Sung-Taik; Nakamura, Kazunori; Kamagata, Yoichi

2011-01-01

We developed a simple, less laborious method to cultivate and isolate obligate anaerobic microorganisms using a six-well plate together with the AnaeroPack System, designated as the six-well plate method. The cultivation efficiency of this method, based on colony-forming units, colony formation time, and colony size, was evaluated with four authentic obligate anaerobes (two methanogenic archaea and two sulfate-reducing bacteria). The method was found to be comparable to or even better than the roll tube method, a technique that is commonly used at present for the cultivation of obligate anaerobes. Further experiments using 21 representative obligate anaerobes demonstrated that all examined anaerobes (11 methanogens, 5 sulfate- or thiosulfate-reducing bacteria, and 5 syntrophs) could form visible colonies on the six-well plate and that these colonies could be successfully subcultured in fresh liquid media. Using this method, an unidentified sulfate-reducing bacterium was successfully isolated from an environmental sample.

Contractual obligations and the sharing of confidential health information in sport.

Science.gov (United States)

Anderson, L

2008-09-01

As an employee, a sports doctor has obligations to their employer, but also professional and widely accepted obligations of a doctor to the patient (in this case the individual team member). The conflict is evident when sports doctors are asked by an athlete to keep personal health information confidential from the coach and team management, and yet both doctor and athlete have employment contracts specifying that such information shall be shared. Recent research in New Zealand shows that despite the presence of an employment contract, there appears to be a wide range of behaviours among sports doctors when an athlete requests that information about them be kept from team management. Many seem willing to honour requests to keep health information about the athlete confidential, thereby being in breach of the employment contract, while others insist on informing team management against the wishes of the athlete. There are a number of potential solutions to this dilemma from forcing doctors to meet their contractual obligations, to limiting the expectations of the employment contract. This paper suggests that at times it may be appropriate to do both, making the position of the doctor clearer and supporting the ability of this group to resist pressure by coaches and management through having a robust code of ethics.

Trust in Supervisor and Job Engagement: Mediating Effects of Psychological Safety and Felt Obligation.

Science.gov (United States)

Basit, Ameer A

2017-11-17

In the social context of job engagement, the role of trust in supervisor in predicting engagement of employees has received attention in research. Very limited research, however, has investigated the mechanisms mediating this dynamic relationship. To address this important gap in knowledge, the aim of this study was to examine psychological safety and felt obligation as two psychological mechanisms mediating the effect of trust in supervisor on job engagement. Drawing from job engagement and social exchange theories, the mediating roles of psychological safety and felt obligation in the trust-engagement relationship were empirically investigated in the Malaysian context. Using self-report questionnaires, data were collected from 337 nurses employed in a public hospital located near Kuala Lumpur, Malaysia. Results fully supported the proposed serial multiple mediator model. Trust in supervisor was indirectly related to job engagement via psychological safety followed by felt obligation. This study provides empirical evidence that trust in supervisor makes employees feel psychologically safe to employ and express their selves in their job roles. This satisfaction of the psychological safety need is interpreted by employees as an important socioemotional benefit that, in turn, makes them feel obligated to pay back to their organization through their enhanced level of job engagement. Implications for theory and practice were discussed.

Institutional review board perspectives on obligations to disclose genetic incidental findings to research participants.

Science.gov (United States)

Gliwa, Catherine; Yurkiewicz, Ilana R; Lehmann, Lisa Soleymani; Hull, Sara Chandros; Jones, Nathan; Berkman, Benjamin E

2016-07-01

Researchers' obligations to disclose genetic incidental findings (GIFs) have been widely debated, but there has been little empirical study of the engagement of institutional review boards (IRBs) with this issue. This article presents data from the first extensive (n = 796) national survey of IRB professionals' understanding of, experience with, and beliefs surrounding GIFs. Most respondents had dealt with questions about GIFs (74%), but only a minority (47%) felt prepared to address them. Although a majority believed that there is an obligation to disclose GIFs (78%), there is still not consensus about the supporting ethical principles. Respondents generally did not endorse the idea that researchers' additional time and effort (7%), and lack of resources (29%), were valid reasons for diminishing a putative obligation. Most (96%) supported a right not to know, but this view became less pronounced (63%) when framed in terms of specific case studies. IRBs are actively engaged with GIFs but have not yet reached consensus. Respondents were uncomfortable with arguments that could be used to limit an obligation to return GIFs. This could indicate that IRBs are providing some of the impetus for the trend toward returning GIFs, although questions remain about the relative contribution of other stakeholders.Genet Med 18 7, 705-711.

Relation between Teachers' Demographic and Professional Profile and Their Attitude towards Ethical Obligations of Teaching Profession

Science.gov (United States)

Goswami, I; Ranjith, L.

2010-01-01

Teachers in higher education are not contrastingly different from the primary and secondary school teachers in terms of their ethical obligations to their stakeholders. However in higher education teachers' professionalism and their attitude towards ethical obligations are believed to be more important for ensuring quality education services. The…

Yucca aloifolia (Asparagaceae) opts out of an obligate pollination mutualism.

Science.gov (United States)

Rentsch, Jeremy D; Leebens-Mack, Jim

2014-12-01

• According to Cope's 'law of the unspecialized' highly dependent species interactions are 'evolutionary dead ends,' prone to extinction because reversion to more generalist interactions is thought to be unlikely. Cases of extreme specialization, such as those seen between obligate mutualists, are cast as evolutionarily inescapable, inevitably leading to extinction rather than diversification of participating species. The pollination mutualism between Yucca plants and yucca moths (Tegeticula and Parategeticula) would seem to be locked into such an obligate mutualism. Yucca aloifolia populations, however, can produce large numbers of fruit lacking moth oviposition scars. Here, we investigate the pollination ecology of Y. aloifolia, in search of the non-moth pollination of a Yucca species.• We perform pollinator exclusion studies on Yucca aloifolia and a sympatric yucca species, Y. filamentosa. We then perform postvisit exclusion treatments, an analysis of dissected fruits, and a fluorescent dye transfer experiment.• As expected, Yucca filamentosa plants set fruit only when inflorescences were exposed to crepuscular and nocturnal pollinating yucca moths. In contrast, good fruit set was observed when pollinators were excluded from Y. aloifolia inflorescences from dusk to dawn, and no fruit set was observed when pollinators were excluded during the day. Follow up experiments indicated that European honeybees (Apis mellifera) were passively yet effectively pollinating Y. aloifolia flowers.• These results indicate that even highly specialized mutualisms may not be entirely obligate interactions or evolutionary dead ends. © 2014 Botanical Society of America, Inc.

To what do we have moral obligations and why? II.

Science.gov (United States)

Gillon, R

1985-06-08

Following up on his 1 June 1985 article on moral obligations to living human beings versus other sentient beings, Gillon focuses on arguments for and against prohuman "speciesism," the claim that "viability" is a justifiable criterion for differentiating between humans that may be killed and those that may not, and claims that "personhood" is a morally relevant differentiating concept. He discusses the positions taken by Peter Singer and Dame Mary Warnock on "speciesism," and the theories of such philosphers as John Locke, Immanuel Kant, and Michael Tooley regarding the essence of personhood. He sees no solid basis for grounding the scope of moral obligations on simple sentience, membership in the human species, or technical differentia such as viability, and concludes that medical ethics still suffers from the lack of an adequate theory on which to base a right to life.

[Between obligation and duty--on deontological codes in medical professions].

Science.gov (United States)

Bartkowiak, Leszek E

2006-01-01

The social role of medical occupations is changing, along with their professional ethics. It could be argued that the role of ethical regulation (ethical codes) in these professions is diminishing. It could be due to ethical standards increasingly taking on character of legal norms. The notion of "moral obligation" is thus subject to transformation, as it progressively denotes legal duty, i.e., coercion. Legal validity of ethical standards is defined by lawyers. The continual tendency of occupational ethics to resemble rules of law may thus question the effect of ethical regulation in medical professions. The latter are performed not only because of official or economical compulsion but also because of moral obligation and the medic's desire to do well. The standing of occupational ethics in the work ofphysician, nurse and pharmacist is a prerequisite for maintaining the high social prestige of these professions.

STATE OBLIGATION ON VIRUS SAMPLE SHARING;FROM COMMON HERITAGE OF MANKIND TO STATE’S SOVEREIGN RIGHT

Directory of Open Access Journals (Sweden)

Nurul Barizah

2015-06-01

Full Text Available The tradition of free international exchange of viruses have been developed by the World Health Organization (WHO probably based on the principle of “Common Heritage of Mankind”.  This tradition lead to legal uncertainty and unfairness in the movement of resources among states and provides an opportunity for developed countries to obtain easy access to viruses of developing countries. Then, International Law has introduced a new regime of “State’s Sovereign Right.” This research focuses on whether Member States have an obligation to share pathogen materials, including viruses for preventing global public health emergency, and whether WHO Collaborating Centers has a right to  share viruses to private sectors. It examines the reason why States should apply that principle. This research is normative legal research by using conceptual approach and  statute approach. This research finds that viruses are part of genetic resources under the meaning of CBD Convention. Accordingly, there is no state obligation under International Law to share it. However, if there is an international human rights obligation to share virus, there should also be an international human rights obligation to assure the access of affordability of drugs and vaccines. Thus, each state will have an equal obligation to enhance the global public health.Key Words : Intellectual Property, Virus Sample Sharing, Common Heritage of Mankind, and State’s Sovereign Right

Controls Over Unliquidated Obligations in the Iraq Relief and Reconstruction Fund

National Research Council Canada - National Science Library

Bowen, Stuart W

2007-01-01

...) are the major recipients of IRRF funds. Obligations are recorded when an authorized agent of the federal government enters into a legally binding agreement to purchase specific goods or services...

Socioeconomic stress and academic adjustment among Asian American adolescents: the protective role of family obligation.

Science.gov (United States)

Kiang, Lisa; Andrews, Kandace; Stein, Gabriela L; Supple, Andrew J; Gonzalez, Laura M

2013-06-01

Socioeconomic stress has long been found to place youth at risk, with low family income conferring disadvantages in adolescents' school achievement and success. This study investigates the role of socioeconomic stress on academic adjustment, and pinpoints family obligation as a possible buffer of negative associations. We examined direct and interactive effects at two time points in the same sample of Asian American adolescents-early high school (N = 180 9th-10th graders; 60 % female) and 2 years later in late high school (N = 156 11th-12th graders; 87% of original sample). Results suggest that socioeconomic stress is indeed associated with poor academic adjustment, measured broadly through self-reported GPA, importance of academic success, and educational aspirations and expectations. Family obligation was positively related to adjustment, and also was found to buffer the negative effects of socioeconomic stress, but only during adolescents' later high school years. Adolescents reporting more family obligation experienced less of the negative effects of financial stress on academic outcomes than those reporting lower obligation. Cultural and developmental implications are discussed in light of these direct and moderating effects.

What are the moral obligations of the traveller in relation to vaccination?

Science.gov (United States)

Dawson, Angus

2007-03-01

More and more people each year are involved in international travel for reasons of business and pleasure. Such travel brings great economic and social benefits but it also has serious potential medical costs because it creates greater opportunities for the spread of infectious disease. In this paper, I discuss the ethical issues relating to a traveller's responsibility to be vaccinated against infectious diseases (where such vaccinations exist). What are the relevant moral obligations, in this situation? What are the boundaries of legitimate restrictions that can be placed upon an individual for the sake of protecting others from disease? Do we have extra special obligations to protect others from harm when we choose to travel abroad (beyond those we might have to other people in our own country)? I explore two different arguments suggesting that we do have an obligation to be vaccinated in this case. The first argument is built upon the potential harm to other people that might arise in the case of vaccination-refusal, and the second argument looks at the need to contribute to the preservation of public goods, such as herd protection.

Are Physicians Obliged to Lead Environmental Sustainability Efforts in Health Care Organizations?

Science.gov (United States)

Macpherson, Cheryl C; Hill, Jonathan

2017-12-01

Climate change threatens health, health care, and the industries and resources upon which these depend. The growing prevalence and severity of its health consequences and economic costs are alarming health professionals and organizations as their professional obligations, grounded in the core value of health, include protecting against these harms. One means of fulfilling these obligations is to lead or support sustainability initiatives that are built upon current, reliable, accurate, and unbiased evidence and collaboratively tailored to meet specific needs and respond to specific contexts. We consider why and how health professionals and organizations should lead or support such initiatives. © 2017 American Medical Association. All Rights Reserved.

Considerations regarding the constitutional obligation determining the financing source for budgetary expenditures

Directory of Open Access Journals (Sweden)

Florentina Camelia Stoica

2016-12-01

Full Text Available This study examines the relation between constitutionality and opportunity in order to adopt regulations in matters of economy and finance. The analysis concerns in particular the regulation process on budgetary expenditures, respectively the constitutional obligation to indicate the source of financing for these expenses. The legal and jurisprudential landmarks identified are likely to reveal the delicate issues of balancing the concurring interests, as well as the constitutionalisation tendency of certain obligations imposed by the law of public finances and, respectively, the Fiscal Responsibility Law in the sense of transforming them into “constitutional criteria” through the application of Article 138 (5 of the Constitution.

Directed graph based carbon flow tracing for demand side carbon obligation allocation

DEFF Research Database (Denmark)

Sun, Tao; Feng, Donghan; Ding, Teng

2016-01-01

In order to achieve carbon emission abatement, some researchers and policy makers have cast their focus on demand side carbon abatement potentials. This paper addresses the problem of carbon flow calculation in power systems and carbon obligation allocation at demand side. A directed graph based...... method for tracing carbon flow is proposed. In a lossy network, matrices such as carbon losses, net carbon intensity (NCI) and footprint carbon intensity (FCI) are obtained with the proposed method and used to allocate carbon obligation at demand side. Case studies based on realistic distribution...... and transmission systems are provided to demonstrate the effectiveness of the proposed method....

Political Obligation, Dirty Hands and Torture; A Moral Evaluation ...

African Journals Online (AJOL)

Political Obligation, Dirty Hands and Torture; A Moral Evaluation. H van Erp. Abstract. The example of a political leader who has to decide whether he would allow the torture of a suspect in order to get information about a ticking bomb has become notorious in ethical discussions concerning the tension between moral ...

International obligations through collective rights: Moving from foreign health assistance to global health governance.

Science.gov (United States)

Meier, Benjamin Mason; Fox, Ashley M

2010-06-15

This article analyzes the growing chasm between international power and state responsibility in health rights, proposing an international legal framework for collective rights - rights that can reform international institutions and empower developing states to realize the determinants of health structured by global forces. With longstanding recognition that many developing state governments cannot realize the health of their peoples without international cooperation, scholars have increasingly sought to codify international obligations under the purview of an evolving human right to health, applying this rights-based approach as a foundational framework for reducing global health inequalities through foreign assistance. Yet the inherent limitations of the individual human rights framework stymie the right to health in impacting the global institutions that are most crucial for realizing underlying determinants of health through the strengthening of primary health care systems. Whereas the right to health has been advanced as an individual right to be realized by a state duty-bearer, the authors find that this limited, atomized right has proven insufficient to create accountability for international obligations in global health policy, enabling the deterioration of primary health care systems that lack the ability to address an expanding set of public health claims. For rights scholars to advance disease protection and health promotion through national primary health care systems - creating the international legal obligations necessary to spur development supportive of the public's health - the authors conclude that scholars must look beyond the individual right to health to create collective international legal obligations commensurate with a public health-centered approach to primary health care. Through the development and implementation of these collective health rights, states can address interconnected determinants of health within and across countries

Duty of care is underpinned by a range of obligations.

Science.gov (United States)

Griffith, Richard

The courts have long established that nurses are in a duty situation and owe a duty of care to their patients (Kent v Griffiths [2001]). Traditionally, the profession set the standard of care and nurses were required to act in accordance with a practice accepted by a responsible body of their peers (Bolam v Friern HMC [1957]).The introduction of the Human Rights Act 1998 gave rise to a positive obligation on government to ensure that laws, policies and procedures are in place to protect violations of human rights. Nurses must now inform their practice with relevant statute law, common law and professional standards in order to properly discharge their duty of care. Richard Griffith considers the law that now underpins a nurse's duty of care and uses a recent report from the Health Service Ombudsman for England to illustrate the obligations that underpin the nurse-patient relationship.

Obligations and responsibilities in radiation protection in the medical field; Obligations et responsabilites en radioprotection dans le domaine medical

Energy Technology Data Exchange (ETDEWEB)

NONE

2011-07-01

This document briefly presents the various obligations and responsibilities of the various actors involved in or concerned by radiation protection in the medical field: the hospital administration (with respect to workers and patients), the physician (authorization and declaration, justification, optimization), the medical electro-radiology operator, the person with expertise in medical radio-physics (PSRPM), the radio-pharmacist (he is required in nuclear medicine with internal use of pharmaceutical product), the personnel with expertise in radiation protection (PCR), and other health professionals

Economic Game Theory to Model the Attenuation of Virulence of an Obligate Intracellular Bacterium.

Science.gov (United States)

Tago, Damian; Meyer, Damien F

2016-01-01

Diseases induced by obligate intracellular pathogens have a large burden on global human and animal health. Understanding the factors involved in the virulence and fitness of these pathogens contributes to the development of control strategies against these diseases. Based on biological observations, a theoretical model using game theory is proposed to explain how obligate intracellular bacteria interact with their host. The equilibrium in such a game shows that the virulence and fitness of the bacterium is host-triggered and by changing the host's defense system to which the bacterium is confronted, an evolutionary process leads to an attenuated strain. Although, the attenuation procedure has already been conducted in practice in order to develop an attenuated vaccine (e.g., with Ehrlichia ruminantium), there was a lack of understanding of the theoretical basis behind this process. Our work provides a model to better comprehend the existence of different phenotypes and some underlying evolutionary mechanisms for the virulence of obligate intracellular bacteria.

Asperger syndrome and the supposed obligation not to bring disabled lives into the world.

Science.gov (United States)

Walsh, Pat

2010-09-01

Asperger syndrome (AS) is an autistic spectrum condition that shares the range of social impairments associated with classic autism widely regarded as disabling, while also often giving rise to high levels of ability in areas such as maths, science, engineering and music. The nature of this striking duality of disability and ability is examined, along with its implications for our thinking about disability and the relevance of levels and kinds of disability to reproductive choices. In particular, it may be seen as posing a challenge to John Harris's influential position in reproductive ethics relating to disability. The paper argues that if, as Harris maintains, there is a quite general moral obligation to avoid bringing disabled lives into the world regardless of the level of disability, then AS must be seen as having a strong claim to be exempt from such an obligation. However, a broader critique of Harris's position leads to the conclusion that, in fact, this putative obligation does not exist.

Do doctors have a moral duty to work in the public health sector? Ethical considerations regarding the social obligations of medicine.

Science.gov (United States)

Aguilera Dreyse, Bernardo; López Gaete, Gonzalo

2017-12-22

This article discusses whether physicians have social obligations and whether these obligations imply a moral duty to work in the public sector. The article focuses on the context of the Chilean health system, which has an unequal distribution of physicians to the detriment of the public sector, thus making the issue a particularly pressing one. After addressing arguments from different ethical theories and some empirical evidence, the article concludes that the physician has some social obligations in relation to a fair distribution of health resources, and that professional excellence should incorporate cultivating virtues related to social justice. In addition, it is argued that the moral duty to work in the public sector can be placed in the context of prima facie obligations which admit exceptions and allow the possibility of conflict with other professional obligations.

Asset retirement obligations: a reporting concern for healthcare facilities.

Science.gov (United States)

Berg, Gary G; Bayes, Paul E; Morgan, Robert G

2008-11-01

FASB statements and SEC guidelines give direction as to how healthcare organizations should account for their asset retirement obligations (AROs) where environmental issues are concerned. A key consideration is that current costs associated with environmental problems, such as encapsulating asbestos, are to be accounted for as part of an asset's cost and depreciated over the asset's remaining life.

Global War on Terrorism: Reported Obligations for the Department of Defense

National Research Council Canada - National Science Library

Pickup, Sharon

2008-01-01

... based on DOD's monthly Supplemental and Cost of War Execution Reports. This report, which responds to this requirement, contains our analysis of DOD's reported obligations for military operations in support of GWOT through September 2008...

The Establishment and Enforcement of Maintenance Obligations in the Relations between Divorced Parents and their Minor Children

Directory of Open Access Journals (Sweden)

Vǎleanu Maricica

2014-08-01

Full Text Available The entry into force of the new Civil Code has, among other merits, that of calling into question the main institutions of private law. The maintenance obligations occupy in its end a central place in the economic relations between parents and children, whereas it was primarily established to ensure good material conditions of growth and education of minors. Through the clearer marking within the present Civil code of the execution of maintenance obligation in nature, in practice the way in which the sentences regarding the establishment of the maintenance obligation in the relations between divorced parents and their underage children are requested and arranged will have to adapt.

42 CFR 411.22 - Reimbursement obligations of primary payers and entities that received payment from primary payers.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Reimbursement obligations of primary payers and... Provisions § 411.22 Reimbursement obligations of primary payers and entities that received payment from... reimburse CMS for any payment if it is demonstrated that the primary payer has or had a responsibility to...

Uranium mine tailings and obligations to future generations

International Nuclear Information System (INIS)

Brook, A.

1980-01-01

Low-level wastes from uranium mine/mill operations, because of their huge volume, are a serious problem, yet relatively little attention has been paid to them. Management of tailings piles and waste liquids in the short term is fairly effective. However these management techniques involve continuous, active treatment of the wastes, which may not continue after operations shut down, and rely on containment structures with a short effective life. Tailings can probably be rendered safe for future generations if sufficient resources are devoted to the task. The central moral question is whether we are obligated to assume the costs of tailings management, or whether it is permissible to pass them on to future generations. The basic moral principle that each person has the same value as any other implies that the generation that reaps the benefits of nuclear power must assume the costs of managing mine tailings and not discriminate in favour of one group of persons, our own generation. The argument that people who may exist in the future have intrinsically less value than people currently alive is not accepted by the author. The methodology for determining obligations to future generations which has been applied to mine/mill wastes could be applied to other nuclear issues, too. (LL)

Obligation of the host state to act transparently towards the foreign investor

Directory of Open Access Journals (Sweden)

Đundić Petar M.

2016-01-01

Full Text Available Provisions on obligation of a host state to act transparently towards foreign investors increasingly often find their way into bilateral investment treaties. Their goal is to provide the investor with all information concerning the investment's legal framework and which he needs in order to make an informed decision with regard to his investment. Certain provisions on transparency are so broad in their scope that they demand from the host state to provide an investor with a possibility to participate in the process of adoption of a state measure that could affect his interest. On the other hand, in arbitral practice the obligation to act transparently is traditionally seen as one of the elements of the fair and equitable treatment standard, although the practice has not so far provided a clear answer as to what is the exact role of this element and what is its relationship with other elements of the standard. The paper contains an analysis of transparency provisions from bilateral investment treaties concluded by the Republic of Serbia. The second part of the paper is dedicated to analysis of arbitral awards in which tribunals considered the transparency obligation as a part of the fair and equitable treatment standard.

42 CFR 23.10 - Under what circumstances may a National Health Service Corps site's reimbursement obligation to...

Science.gov (United States)

2010-10-01

... Service Corps site's reimbursement obligation to the Federal Government be waived? 23.10 Section 23.10... National Health Service Corps site's reimbursement obligation to the Federal Government be waived? (a) The Secretary may waive in whole or in part the reimbursement requirements of section 334(a)(3) of the Act if he...

24 CFR 891.415 - Obligations of the household or family.

Science.gov (United States)

2010-04-01

... family. 891.415 Section 891.415 Housing and Urban Development Regulations Relating to Housing and Urban... Project Management § 891.415 Obligations of the household or family. This section shall apply to capital... E of this part. (a) Requirements. The household (or family, as applicable) shall: (1) Pay amounts...

Compliance with annual obligation 2011 for renewable energy transport and obligation with regard to fuels and air pollution; Naleving jaarverplichting 2011 hernieuwbare energie vervoer en verplichting brandstoffen luchtverontreiniging

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-06-15

The renewable energy transport regulation is to ensure that an increasing percentage of the fuels used for road transport and mobile machinery consists of renewable energy. In the year 2011 the renewable energy obligation was 4.25% (biofuels) on an energy basis. The fuels air pollution regulation is to ensure that less CO2 is emitted throughout the chain from fuel production to combustion in the engine. For 2011 there is a reporting obligation, but is no emission reduction obligation. The year 2011 was the first year in which companies have submitted data to the Dutch Emissions Authority (NEA) on biofuels. This report was prepared on the basis of these submitted data [Dutch] De regelgeving hernieuwbare energie vervoer is erop gericht dat een steeds groter percentage van de brandstoffen die worden ingezet voor het wegverkeer en mobiele machines bestaat uit hernieuwbare energie. In 2011 bedroeg de jaarverplichting hernieuwbare energie 4,25% op energiebasis. De regelgeving brandstoffen luchtverontreiniging is erop gericht dat er steeds minder CO2 wordt uitgestoten in de gehele keten vanaf de productie van de brandstof tot en met de verbranding in de motor. Voor 2011 is er een rapportageplicht, er is geen emissiereductieverplichting. Het jaar 2011 was het eerste jaar waarin bedrijven de gegevens over hun uitgeslagen biobrandstoffen bij de NEa hebben ingediend. Dit rapport is opgesteld op basis van deze ingediende gegevens.

Students Computer Skills in Faculty of Education

Directory of Open Access Journals (Sweden)

Mehmet Caglar

2010-09-01

Full Text Available Nowadays; the usage of technology is not a privilege but an obligation. Technological developments influence structures andfunctions of educational institutions. It is also expected from the teachers that they integrate technology in their lessons inorder to educate the individuals of information society. This research has covered 145(68 female, 78 male students, studying inNear East University Faculty of Education. The Computer Skills Scale developed by Güçlü (2010 was used as a data collectingtool. Data were analysed using SPSS software program. In this study, students’ computer skills were investigated; the variationsin the relationships between computer skills and (a gender, (b family’s net monthly income, (c presence of computers athome, (d presence of a computer laboratory at school and (e parents’ computer skills were examined. Frequency analysis,percentage and mean calculations were used. In addition, t-test and multi-variate analysis were used to look at the relationshipbetween different variables. As a result of this study, a statistically significant relationship between computer skills of studentswho had a computer at home and computer skills of those who didn’t have a computer at home were found.

High hydrostatic pressure adaptive strategies in an obligate piezophile Pyrococcus yayanosii

KAUST Repository

Michoud, Gregoire; Jebbar, Mohamed

2016-01-01

Pyrococcus yayanosii CH1, as the first and only obligate piezophilic hyperthermophilic microorganism discovered to date, extends the physical and chemical limits of life on Earth. It was isolated from the Ashadze hydrothermal vent at 4,100 m depth. Multi-omics analyses were performed to study the mechanisms used by the cell to cope with high hydrostatic pressure variations. In silico analyses showed that the P. yayanosii genome is highly adapted to its harsh environment, with a loss of aromatic amino acid biosynthesis pathways and the high constitutive expression of the energy metabolism compared with other non-obligate piezophilic Pyrococcus species. Differential proteomics and transcriptomics analyses identified key hydrostatic pressure-responsive genes involved in translation, chemotaxis, energy metabolism (hydrogenases and formate metabolism) and Clustered Regularly Interspaced Short Palindromic Repeats sequences associated with Cellular apoptosis susceptibility proteins.

High hydrostatic pressure adaptive strategies in an obligate piezophile Pyrococcus yayanosii

KAUST Repository

Michoud, Gregoire

2016-06-02

Pyrococcus yayanosii CH1, as the first and only obligate piezophilic hyperthermophilic microorganism discovered to date, extends the physical and chemical limits of life on Earth. It was isolated from the Ashadze hydrothermal vent at 4,100 m depth. Multi-omics analyses were performed to study the mechanisms used by the cell to cope with high hydrostatic pressure variations. In silico analyses showed that the P. yayanosii genome is highly adapted to its harsh environment, with a loss of aromatic amino acid biosynthesis pathways and the high constitutive expression of the energy metabolism compared with other non-obligate piezophilic Pyrococcus species. Differential proteomics and transcriptomics analyses identified key hydrostatic pressure-responsive genes involved in translation, chemotaxis, energy metabolism (hydrogenases and formate metabolism) and Clustered Regularly Interspaced Short Palindromic Repeats sequences associated with Cellular apoptosis susceptibility proteins.

Green obligations at the service of the energy and ecological transition

International Nuclear Information System (INIS)

Laville, Dorine; Phantharangsi, Maryvonne; Monnoyer-Smith, Laurence; Besson, Leo

2016-09-01

Green obligations are an important lever for the financing of energy transition as they allow enterprises and public bodies to finance their environmental projects, notably their investments and infrastructures. They comprise a reporting on financed investments and the description of the green characteristic of the financed projects. This publication proposes an overview of this arrangement which has been introduced in 2007 and has been displaying a strong development since 2013, and was also boosted by the COP21. The market diversification and internationalisation are outlined, and concern large companies, private banks, and local and regional communities, with rather well identified objectives. The publication outlines that the precise definition of green obligations is however still missing, that private and public initiatives are emerging to structure this market. It finally outlines the need for a harmonisation of reporting standards

Developing a cultural model of caregiving obligations for elderly Chinese wives.

Science.gov (United States)

Holroyd, Eleanor

2005-06-01

This article addresses the dilemmas of elderly Chinese women as spousal caregivers in Hong Kong in the 1990s. An in-depth ethnographic approach was used to draw on a convenience sample of 20 elderly wives who were caregivers from Hong Kong. At the conceptual level, the discussion highlights how caregiving is rooted in complex, culturally-based models of contemporary practices, sociohistoric patterns, and gender-specific obligations. The key themes identified were marital duty-bound roles and responsibilities, reciprocity and burden, public guidelines and upholding reputations as Chinese wives, monetary restrictions, affection as an emotional force to sustain caregiving, effects of the caregiving role, and the creation of self-identity through caregiving. The model proposed for interpreting elderly Chinese wives' caregiving obligations highlights the tension-filled links between Confucianism and government guidelines, early and ongoing socializing experiences, and self-identity.

High hydrostatic pressure adaptive strategies in an obligate piezophile Pyrococcus yayanosii

Science.gov (United States)

Michoud, Grégoire; Jebbar, Mohamed

2016-01-01

Pyrococcus yayanosii CH1, as the first and only obligate piezophilic hyperthermophilic microorganism discovered to date, extends the physical and chemical limits of life on Earth. It was isolated from the Ashadze hydrothermal vent at 4,100 m depth. Multi-omics analyses were performed to study the mechanisms used by the cell to cope with high hydrostatic pressure variations. In silico analyses showed that the P. yayanosii genome is highly adapted to its harsh environment, with a loss of aromatic amino acid biosynthesis pathways and the high constitutive expression of the energy metabolism compared with other non-obligate piezophilic Pyrococcus species. Differential proteomics and transcriptomics analyses identified key hydrostatic pressure-responsive genes involved in translation, chemotaxis, energy metabolism (hydrogenases and formate metabolism) and Clustered Regularly Interspaced Short Palindromic Repeats sequences associated with Cellular apoptosis susceptibility proteins. PMID:27250364

Constant Proportion Debt Obligations (CPDOs)

DEFF Research Database (Denmark)

Cont, Rama; Jessen, Cathrine

2012-01-01

be made arbitrarily small—and thus the credit rating arbitrarily high—by increasing leverage, but the ratings obtained strongly depend on assumptions on the credit environment (high spread or low spread). More importantly, CPDO loss distributions are found to exhibit a wide range of tail risk measures......Constant Proportion Debt Obligations (CPDOs) are structured credit derivatives that generate high coupon payments by dynamically leveraging a position in an underlying portfolio of investment-grade index default swaps. CPDO coupons and principal notes received high initial credit ratings from...... the major rating agencies, based on complex models for the joint transition of ratings and spreads for all names in the underlying portfolio. We propose a parsimonious model for analysing the performance of CPDO strategies using a top-down approach that captures the essential risk factors of the CPDO. Our...

The moral division of labor and obligations of citizens at war

DEFF Research Database (Denmark)

Dige, Morten

Contemporary just war thinking has focused primarily on the roles of three agents in war: governments, soldiers and civilians considered as potential non-combatant victims of military attack: what are the responsibilities, permissions, rights and obligations of these? Relatively little has been s...

The heme biosynthetic pathway of the obligate Wolbachia endosymbiont of Brugia malayi as a potential anti-filarial drug target.

Directory of Open Access Journals (Sweden)

Bo Wu

2009-07-01

Full Text Available Filarial parasites (e.g., Brugia malayi, Onchocerca volvulus, and Wuchereria bancrofti are causative agents of lymphatic filariasis and onchocerciasis, which are among the most disabling of neglected tropical diseases. There is an urgent need to develop macro-filaricidal drugs, as current anti-filarial chemotherapy (e.g., diethylcarbamazine [DEC], ivermectin and albendazole can interrupt transmission predominantly by killing microfilariae (mf larvae, but is less effective on adult worms, which can live for decades in the human host. All medically relevant human filarial parasites appear to contain an obligate endosymbiotic bacterium, Wolbachia. This alpha-proteobacterial mutualist has been recognized as a potential target for filarial nematode life cycle intervention, as antibiotic treatments of filarial worms harboring Wolbachia result in the loss of worm fertility and viability upon antibiotic treatments both in vitro and in vivo. Human trials have confirmed this approach, although the length of treatments, high doses required and medical counter-indications for young children and pregnant women warrant the identification of additional anti-Wolbachia drugs.Genome sequence analysis indicated that enzymes involved in heme biosynthesis might constitute a potential anti-Wolbachia target set. We tested different heme biosynthetic pathway inhibitors in ex vivo B. malayi viability assays and report a specific effect of N-methyl mesoporphyrin (NMMP, which targets ferrochelatase (FC, the last step. Our phylogenetic analysis indicates evolutionarily significant divergence between Wolbachia heme genes and their human homologues. We therefore undertook the cloning, overexpression and analysis of several enzymes of this pathway alongside their human homologues, and prepared proteins for drug targeting. In vitro enzyme assays revealed a approximately 600-fold difference in drug sensitivities to succinyl acetone (SA between Wolbachia and human 5

Civil Law Obligations in the Financial Law Regulations A seminar at the Faculty of Law and Administration, Torun, 24 March 2015

Directory of Open Access Journals (Sweden)

Mirosław Bączyk

2015-06-01

Full Text Available The problem, which is examined in the study, is the legal way of creation of civil law obligations. Civil law obligations are created by civil law transactions (especially by contracts. There is the question, if civil law obligations can be created directly by the legal regulations? This issue is important for the legal and financial relations between the Treasury, local government and other legal persons.

"You Can See How Things Will End by the Way They Begin": The Contribution of Early Mutual Obligations for the Development of the Psychological Contract.

Science.gov (United States)

Farnese, Maria Luisa; Livi, Stefano; Barbieri, Barbara; Schalk, René

2018-01-01

This study explores dynamic processes in the development of the psychological contract, focusing on the interaction of obligations related to the two parties (i.e., employees' perceptions of both their own and the organization's obligations fulfillment) on attitudinal outcomes (organizational commitment and turnover intention) during the initial stage of the employment relationship. In a twofold cross-sectional and two-wave study on newly hired correctional police officers, we examined: (a) whether perception of organizational obligations fulfillment moderates the relationship between employee obligations and their attitudes (Study 1, n.500); (b) the direct and moderated influence of perceived obligations at the entrance stage on those in the following months (Study 2, n.223). Results confirmed that, in the eyes of the newcomer, the obligations fulfillment of each of the two parties interact, having an additional effect beyond the main direct effects, in influencing both subsequent obligations perceptions and, through this, the outcome variables. Theoretical and practical implications of the findings are discussed.

Under the (legal radar screen: global health initiatives and international human rights obligations

Directory of Open Access Journals (Sweden)

Hammonds Rachel

2012-11-01

Full Text Available Abstract Background Given that many low income countries are heavily reliant on external assistance to fund their health sectors the acceptance of obligations of international assistance and cooperation with regard to the right to health (global health obligations is insufficiently understood and studied by international health and human rights scholars. Over the past decade Global Health Initiatives, like the Global Fund to fight AIDS, Tuberculosis and Malaria (Global Fund have adopted novel approaches to engaging with stakeholders in high and low income countries. This article explores how this experience impacted on acceptance of the international obligation to (help fulfil the right to health beyond borders. Methods The authors conducted an extensive review of international human rights law literature, transnational legal process literature, global public health literature and grey literature pertaining to Global Health Initiatives. To complement this desk work and deepen their understanding of how and why different legal norms evolve the authors conducted 19 in-depth key informant interviews with actors engaged with three stakeholders; the European Union, the United States and Belgium. The authors then analysed the interviews through a transnational legal process lens. Results Through according value to the process of examining how and why different legal norms evolve transnational legal process offers us a tool for engaging with the dynamism of developments in global health suggesting that operationalising global health obligations could advance the right to health for all. Conclusions In many low-income countries the health sector is heavily dependent on external assistance to fulfil the right to health of people thus it is vital that policies and tools for delivering reliable, long-term assistance are developed so that the right to health for all becomes more than a dream. Our research suggests that the Global Fund experience offers

Under the (legal) radar screen: global health initiatives and international human rights obligations

Science.gov (United States)

2012-01-01

Background Given that many low income countries are heavily reliant on external assistance to fund their health sectors the acceptance of obligations of international assistance and cooperation with regard to the right to health (global health obligations) is insufficiently understood and studied by international health and human rights scholars. Over the past decade Global Health Initiatives, like the Global Fund to fight AIDS, Tuberculosis and Malaria (Global Fund) have adopted novel approaches to engaging with stakeholders in high and low income countries. This article explores how this experience impacted on acceptance of the international obligation to (help) fulfil the right to health beyond borders. Methods The authors conducted an extensive review of international human rights law literature, transnational legal process literature, global public health literature and grey literature pertaining to Global Health Initiatives. To complement this desk work and deepen their understanding of how and why different legal norms evolve the authors conducted 19 in-depth key informant interviews with actors engaged with three stakeholders; the European Union, the United States and Belgium. The authors then analysed the interviews through a transnational legal process lens. Results Through according value to the process of examining how and why different legal norms evolve transnational legal process offers us a tool for engaging with the dynamism of developments in global health suggesting that operationalising global health obligations could advance the right to health for all. Conclusions In many low-income countries the health sector is heavily dependent on external assistance to fulfil the right to health of people thus it is vital that policies and tools for delivering reliable, long-term assistance are developed so that the right to health for all becomes more than a dream. Our research suggests that the Global Fund experience offers lessons to build on. PMID

Under the (legal) radar screen: global health initiatives and international human rights obligations.

Science.gov (United States)

Hammonds, Rachel; Ooms, Gorik; Vandenhole, Wouter

2012-11-15

Given that many low income countries are heavily reliant on external assistance to fund their health sectors the acceptance of obligations of international assistance and cooperation with regard to the right to health (global health obligations) is insufficiently understood and studied by international health and human rights scholars. Over the past decade Global Health Initiatives, like the Global Fund to fight AIDS, Tuberculosis and Malaria (Global Fund) have adopted novel approaches to engaging with stakeholders in high and low income countries. This article explores how this experience impacted on acceptance of the international obligation to (help) fulfil the right to health beyond borders. The authors conducted an extensive review of international human rights law literature, transnational legal process literature, global public health literature and grey literature pertaining to Global Health Initiatives. To complement this desk work and deepen their understanding of how and why different legal norms evolve the authors conducted 19 in-depth key informant interviews with actors engaged with three stakeholders; the European Union, the United States and Belgium. The authors then analysed the interviews through a transnational legal process lens. Through according value to the process of examining how and why different legal norms evolve transnational legal process offers us a tool for engaging with the dynamism of developments in global health suggesting that operationalising global health obligations could advance the right to health for all. In many low-income countries the health sector is heavily dependent on external assistance to fulfil the right to health of people thus it is vital that policies and tools for delivering reliable, long-term assistance are developed so that the right to health for all becomes more than a dream. Our research suggests that the Global Fund experience offers lessons to build on.

The Obligation to Provide Free Basic Education in South Africa: An ...

African Journals Online (AJOL)

Potchefstroom Electronic Law Journal/Potchefstroomse Elektroniese Regsblad ... In South Africa many learners are denied the right to basic education because of the levying of school fees and other educational charges, in spite of the international obligation imposed on government to provide free primary education.

Amino acid transporter expansions associated with the evolution of obligate endosymbiosis in sap-feeding insects (Hemiptera: sternorrhyncha).

Science.gov (United States)

Dahan, Romain A; Duncan, Rebecca P; Wilson, Alex C C; Dávalos, Liliana M

2015-03-25

Mutualistic obligate endosymbioses shape the evolution of endosymbiont genomes, but their impact on host genomes remains unclear. Insects of the sub-order Sternorrhyncha (Hemiptera) depend on bacterial endosymbionts for essential amino acids present at low abundances in their phloem-based diet. This obligate dependency has been proposed to explain why multiple amino acid transporter genes are maintained in the genomes of the insect hosts. We implemented phylogenetic comparative methods to test whether amino acid transporters have proliferated in sternorrhynchan genomes at rates grater than expected by chance. By applying a series of methods to reconcile gene and species trees, inferring the size of gene families in ancestral lineages, and simulating the null process of birth and death in multi-gene families, we uncovered a 10-fold increase in duplication rate in the AAAP family of amino acid transporters within Sternorrhyncha. This gene family expansion was unmatched in other closely related clades lacking endosymbionts that provide essential amino acids. Our findings support the influence of obligate endosymbioses on host genome evolution by both inferring significant expansions of gene families involved in symbiotic interactions, and discovering increases in the rate of duplication associated with multiple emergences of obligate symbiosis in Sternorrhyncha.

The Scope of the Obligation to Respect and to Ensure Respect for International Humanitarian Law

Directory of Open Access Journals (Sweden)

Tomasz Zych

2009-10-01

Full Text Available This article disputes what seems to have become the dominant interpretation of the obligation to respect and to ensure respect for International Humanitarian Law, as codified in common Article 1 of the Geneva Conventions and in Article 1(1 of Additional Protocol I. According to this dominant interpretation, States are required to take all appropriate measures to ensure that IHL is observed universally, including by other States and by non-State actors operating in other States. It is argued that the intention of the High Contracting Parties, coupled with their subsequent practice, calls for a much more narrow interpretation of that obligation. Cet article conteste ce qui semble être devenue l’interprétation dominante de l’obligation de respecter et de faire respecter le Droit International Humanitaire, tel que codifiée à l’article 1 commun aux Conventions de Genève et à l’article 1(1 du Protocole additionnel I. Selon cette interprétation dominante, les États doivent prendre toutes les mesures appropriées pour assurer que le DIH soit observé de façon universelle, y compris par d’autres États ainsi que par des acteurs non étatiques qui opèrent à l’intérieur d’autres États. On soutient que l’intention des Hautes Parties contractantes, en conjonction avec leur pratique subséquentes, laisse entendre une interprétation beaucoup plus étroite de cette obligation.

20 CFR 1002.261 - Who is responsible for funding any plan obligation to provide the employee with pension benefits?

Science.gov (United States)

2010-04-01

... obligation to provide the employee with pension benefits? 1002.261 Section 1002.261 Employees' Benefits... and Benefits Pension Plan Benefits § 1002.261 Who is responsible for funding any plan obligation to provide the employee with pension benefits? With the exception of multiemployer plans, which have separate...

12 CFR 995.4 - Book-entry procedure for Financing Corporation obligations.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Book-entry procedure for Financing Corporation... FINANCING CORPORATION OPERATIONS § 995.4 Book-entry procedure for Financing Corporation obligations. (a) Authority. Any Federal Reserve Bank shall have authority to apply book-entry procedure to Financing...

Exploiter la Littérature en Classe du Fle: Allah N'est Pas Obligé D ...

African Journals Online (AJOL)

Prof

allons exploiter un extrait d'un texte littéraire: Allah n'est pas obligé d'Ahmadou. Kourouma au niveau A1/A2 du CECR. Dans Allah n'est pas obligé l'écrivain ivoirien dépeint le phénomène d'enfant soldat à travers la vie et les pérégrinations de Birahima le protagoniste. Etat de lieu. Pour se tirer de la situation ci-dessus, ...

12 CFR 714.9 - Are indirect leasing arrangements subject to the purchase of eligible obligation limit set forth...

Science.gov (United States)

2010-01-01

... the purchase of eligible obligation limit set forth in § 701.23 of this chapter? 714.9 Section 714.9....9 Are indirect leasing arrangements subject to the purchase of eligible obligation limit set forth... underwriting decision and that the lease contract is assigned to you very soon after it is signed by the member...

“You Can See How Things Will End by the Way They Begin”: The Contribution of Early Mutual Obligations for the Development of the Psychological Contract

Science.gov (United States)

Farnese, Maria Luisa; Livi, Stefano; Barbieri, Barbara; Schalk, René

2018-01-01

This study explores dynamic processes in the development of the psychological contract, focusing on the interaction of obligations related to the two parties (i.e., employees’ perceptions of both their own and the organization’s obligations fulfillment) on attitudinal outcomes (organizational commitment and turnover intention) during the initial stage of the employment relationship. In a twofold cross-sectional and two-wave study on newly hired correctional police officers, we examined: (a) whether perception of organizational obligations fulfillment moderates the relationship between employee obligations and their attitudes (Study 1, n.500); (b) the direct and moderated influence of perceived obligations at the entrance stage on those in the following months (Study 2, n.223). Results confirmed that, in the eyes of the newcomer, the obligations fulfillment of each of the two parties interact, having an additional effect beyond the main direct effects, in influencing both subsequent obligations perceptions and, through this, the outcome variables. Theoretical and practical implications of the findings are discussed. PMID:29719521

Employers' Occupational Health and Safety Training Obligations in Framework Directive and Training Procedure and Rules in Turkey

OpenAIRE

Nuray Gökçek Karaca; Berrin Gökçek

2015-01-01

Employers occupational safety and health training obligations are regulated in 89/391/EEC Framework Directive and also in 6331 numbered Occupational Health and Safety Law in Turkey. The main objective of this research is to determine and evaluate the employers’ occupational health and safety training obligations in Framework Directive in comparison with the 6331 numbered Occupational Health and Safety Law and to examine training principles in Turkey. For this purpose, ...

Inclusive governance: the role of knowledge in fulfilling the obligations of citizens

CSIR Research Space (South Africa)

Karar, E

2016-08-01

Full Text Available Inclusive governance and citizen engagement in governing water is important in enhancing service delivery. Good citizens endorse their obligations alongside their respective rights. To date, much focus has been on the rights approach to fulfil basic...

24 CFR 1000.418 - Can grant funds be used to pay costs incurred when issuing notes or other obligations?

Science.gov (United States)

2010-04-01

... costs incurred when issuing notes or other obligations? 1000.418 Section 1000.418 Housing and Urban... to pay costs incurred when issuing notes or other obligations? Yes. Other costs that can be paid using grant funds include but are not limited to the costs of servicing and trust administration, and...

On A Recent Theory of 'Legal Obligation'

Directory of Open Access Journals (Sweden)

Bruno Leoni

2009-02-01

Full Text Available This paper, by the late Bruno Leoni, was originally published in the Italian journal Il Politico in 1966. In the article, Leoni reviews H.L.A. Hart’s The Concept of Law (1961. Hart first analyzes the concept of law by resorting to the classical concept of “obligation.” But he later tries a “fresh start” by resorting to the concept of “secondary rules.” In his review, Leoni argues that the former attempt is confronted with serious difficulties, and that the latter attempt (to which professor Hart possibly resorts in view of overcoming some of said difficulties is ultimately inconsistent with the former

Obligation de rendre compte | CRDI - Centre de recherches pour le ...

International Development Research Centre (IDRC) Digital Library (Canada)

Les mécanismes qui appuient l'obligation de rendre compte, comme les comités spéciaux, les unités organisationnelles spécialisées et les pratiques administratives quotidiennes, englobent la gestion du risque, les audits, les évaluations, l'accès à l'information, la production de rapports à l'intention du Parlement et la ...

Dominant obligate anaerobes revealed in lower respiratory tract infection in horses by 16S rRNA gene sequencing.

Science.gov (United States)

Kinoshita, Yuta; Niwa, Hidekazu; Katayama, Yoshinari; Hariu, Kazuhisa

2014-04-01

Obligate anaerobes are important etiological agents in pneumonia or pleuropneumonia in horses, because they are isolated more commonly from ill horses that have died or been euthanized than from those that survive. We performed bacterial identification and antimicrobial susceptibility testing for obligate anaerobes to establish effective antimicrobial therapy. We used 16S rRNA gene sequencing to identify 58 obligate anaerobes and compared the results with those from a phenotypic identification kit. The identification results of 16S rRNA gene sequencing were more reliable than those of the commercial kit. We concluded that genera Bacteroides and Prevotella-especially B. fragilis and P. heparinolytica-are dominant anaerobes in lower respiratory tract infection in horses; these organisms were susceptible to metronidazole, imipenem and clindamycin.

Poor energy poor: Energy saving obligations, distributional effects, and the malfunction of the priority group

International Nuclear Information System (INIS)

Moser, Simon

2013-01-01

The European Union’s Energy Efficiency Directive forces the Member States to install energy efficiency obligation schemes. In a first step, this paper identifies the distributional effects caused by this policy instrument which occur when energy efficiency measures are implemented (phase of delivery) and when its costs are passed on to the society (phase of financing). In the phase of delivery, suppliers prefer to implement measures at the property of those customers which enable them to minimise their costs, i.e. enterprises with large energy savings potentials and high-income households who can contribute a greater share of the costs. In the phase of financing, distributional effects occur when the costs of the scheme are passed on from the obliged suppliers to their customers, primarily affecting less competitive customers, i.e. households and small enterprises. In the British scheme, the so-called priority group was installed in order to decrease distributional effects and to support energy poor households. In a second step, this paper evaluates approaches to reduce energy poverty and indicates ineffectiveness, high transaction costs and incoherency with the aims of the obligation scheme. Alternative approaches to tackle energy poverty are briefly described. - Highlights: • The paper discusses distributional effects of energy efficiency obligations. • Significant distributional effects occur when measures are implemented. • Significant distributional effects occur when costs are passed on to the customers. • Suppliers face problems to identify energy poor households. • The priority group contradicts the scheme’s intention of cost minimisation

Host-microbe and microbe-microbe interactions in the evolution of obligate plant parasitism.

Science.gov (United States)

Kemen, Ariane C; Agler, Matthew T; Kemen, Eric

2015-06-01

Research on obligate biotrophic plant parasites, which reproduce only on living hosts, has revealed a broad diversity of filamentous microbes that have independently acquired complex morphological structures, such as haustoria. Genome studies have also demonstrated a concerted loss of genes for metabolism and lytic enzymes, and gain of diversity of genes coding for effectors involved in host defense suppression. So far, these traits converge in all known obligate biotrophic parasites, but unexpected genome plasticity remains. This plasticity is manifested as transposable element (TE)-driven increases in genome size, observed to be associated with the diversification of virulence genes under selection pressure. Genome expansion could result from the governing of the pathogen response to ecological selection pressures, such as host or nutrient availability, or to microbial interactions, such as competition, hyperparasitism and beneficial cooperations. Expansion is balanced by alternating sexual and asexual cycles, as well as selfing and outcrossing, which operate to control transposon activity in populations. In turn, the prevalence of these balancing mechanisms seems to be correlated with external biotic factors, suggesting a complex, interconnected evolutionary network in host-pathogen-microbe interactions. Therefore, the next phase of obligate biotrophic pathogen research will need to uncover how this network, including multitrophic interactions, shapes the evolution and diversity of pathogens. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

Mechanisms of Funding for Universal Service Obligations: the Electricity Case

International Nuclear Information System (INIS)

Mirabel, Francois; Poudou, Jean-Christophe

2001-06-01

The transition towards a more competitive regime in network industries (and specially in electricity sector) raises the relevant question of funding for the Universal Service Obligations (USOs). Our paper focuses on two ways of funding for universal service and equal treatment obligations (?Ubiquity and Non Discrimination constraints?): the funding through access charge (CS regime) or taxation (T regime). Using a network model including competition between an historical monopoly (in charge for the USOs) and an entrant, we obtain some results concerning gains and losses of social welfare due to those mechanisms. We show that most of the time it is socially better to let the historical monopoly be active whatever the type of funding for USOs applying, and whatever profitability of the firms is. However, when the entrant is active, we can highlight that the introduction of the T regime (compared to the CS one) implies either welfare deterioration or an entry prevention strategy by the historical firm. Therefore, the T regime could not be an argument for the regulator to promote vertical separation of the historical firm (according to the European community line). (authors)

Mechanisms of funding for Universal Service Obligations: the electricity case

International Nuclear Information System (INIS)

Mirabel, F.; Poudou, J.C.

2004-01-01

The transition towards a more competitive regime in network industries (and specially in electricity sector) raises the relevant question of funding for the Universal Service Obligations (USOs). Our paper focuses on two ways of funding for universal service and equal treatment obligations ''Ubiquity and Nondiscrimination constraints, UND'': the funding through access charge (CS regime) or taxation (T regime). Using a network model including competition between a historical monopoly (in charge for the USOs) and an entrant, we obtain some results concerning gains and losses of social welfare due to those mechanisms. We show that most of the time it is socially better to let the historical monopoly be active whatever the type of funding for USOs applying, and whatever profitability of the firms is. However, when the entrant is active, we can highlight that the introduction of the T regime (compared to the CS one) implies either welfare deterioration or an entry prevention strategy by the historical firm. Therefore, the T regime could not be an argument for the regulator to promote vertical separation of the historical firm (according to the European community line). (author)

Mechanisms of funding for Universal Service Obligations. The electricity case

International Nuclear Information System (INIS)

Mirabel, Francois; Poudou, Jean-Christophe

2004-01-01

The transition towards a more competitive regime in network industries (and specially in electricity sector) raises the relevant question of funding for the Universal Service Obligations (USOs). Our paper focuses on two ways of funding for universal service and equal treatment obligations ('Ubiquity and Nondiscrimination constraints, UND'): the funding through access charge (CS regime) or taxation (T regime). Using a network model including competition between a historical monopoly (in charge for the USOs) and an entrant, we obtain some results concerning gains and losses of social welfare due to those mechanisms. We show that most of the time it is socially better to let the historical monopoly be active whatever the type of funding for USOs applying, and whatever profitability of the firms is. However, when the entrant is active, we can highlight that the introduction of the T regime (compared to the CS one) implies either welfare deterioration or an entry prevention strategy by the historical firm. Therefore, the T regime could not be an argument for the regulator to promote vertical separation of the historical firm (according to the European community line)

31 CFR 354.5 - Obligations of Sallie Mae; no adverse claims.

Science.gov (United States)

2010-07-01

...-ENTRY SECURITIES OF THE STUDENT LOAN MARKETING ASSOCIATION (SALLIE MAE) § 354.5 Obligations of Sallie... a Federal Reserve Bank or otherwise as provided in § 354.4(c)(1), for the purposes of this part 354, Sallie Mae and the Federal Reserve Banks shall treat the Participant to whose Securities Account an...

Nitric oxide is an obligate bacterial nitrification intermediate produced by hydroxylamine oxidoreductase.

Science.gov (United States)

Caranto, Jonathan D; Lancaster, Kyle M

2017-08-01

Ammonia (NH 3 )-oxidizing bacteria (AOB) emit substantial amounts of nitric oxide (NO) and nitrous oxide (N 2 O), both of which contribute to the harmful environmental side effects of large-scale agriculture. The currently accepted model for AOB metabolism involves NH 3 oxidation to nitrite (NO 2 - ) via a single obligate intermediate, hydroxylamine (NH 2 OH). Within this model, the multiheme enzyme hydroxylamine oxidoreductase (HAO) catalyzes the four-electron oxidation of NH 2 OH to NO 2 - We provide evidence that HAO oxidizes NH 2 OH by only three electrons to NO under both anaerobic and aerobic conditions. NO 2 - observed in HAO activity assays is a nonenzymatic product resulting from the oxidation of NO by O 2 under aerobic conditions. Our present study implies that aerobic NH 3 oxidation by AOB occurs via two obligate intermediates, NH 2 OH and NO, necessitating a mediator of the third enzymatic step.

From a pluralism of grounds to proto-legal relations: accounting for the grounds of obligations of justice

OpenAIRE

Pavlakos, Georgios

2017-01-01

In this paper I discuss critically Mathias Risse's paper “Responsibility and Global Justice.” First, I argue that for Risse's pluralist account of the grounds of justice to hold together, there is need to presuppose a monist standpoint which ultimately contributes to grounding principles of justice. Second, I point out that Risse's understanding of obligations of accountability and justification is rather narrow in that it functions as an addendum to obligations of justice. Conversely, I will...

Social Physique Anxiety, Obligation to Exercise, and Exercise Choices among College Students

Science.gov (United States)

Chu, Hui-Wen; Bushman, Barbara A.; Woodard, Rebecca J.

2008-01-01

Objective: The authors examined relationships among social physique anxiety, obligation to exercise, and exercise choices. Participants and Methods: College students (N = 337; 200 women, 137 men) volunteered to complete 3 questionnaires: the Social Physique Anxiety Scale (SPAS), Obligatory Exercise Questionnaire (OEQ), and Physical Activity…

25 CFR 141.58 - Records, reports, and obligations of reservation business owners.

Science.gov (United States)

2010-04-01

... shall keep records in accordance with generally accepted accounting principles. (b) Each reservation... 25 Indians 1 2010-04-01 2010-04-01 false Records, reports, and obligations of reservation business... ACTIVITIES BUSINESS PRACTICES ON THE NAVAJO, HOPI AND ZUNI RESERVATIONS Enforcement Powers, Procedures and...

16 CFR 240.11 - Wholesaler or third party performance of seller's obligations.

Science.gov (United States)

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Wholesaler or third party performance of seller's obligations. 240.11 Section 240.11 Commercial Practices FEDERAL TRADE COMMISSION GUIDES AND TRADE PRACTICE RULES GUIDES FOR ADVERTISING ALLOWANCES AND OTHER MERCHANDISING PAYMENTS AND SERVICES...

The National Guard Meeting Its Obligation to Provide Capable Forces for Homeland Security

National Research Council Canada - National Science Library

Sellars, Thomas J

2006-01-01

... (warfighting versus domestic support/homeland security) be harmonized to best posture the Guard to meet both its state obligations and at the same time continue to play a pivotal role in joint warfighting and stability operations...

49 CFR 17.11 - What are the Secretary's obligations in interstate situations?

Science.gov (United States)

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false What are the Secretary's obligations in interstate situations? 17.11 Section 17.11 Transportation Office of the Secretary of Transportation INTERGOVERNMENTAL REVIEW OF DEPARTMENT OF TRANSPORTATION PROGRAMS AND ACTIVITIES § 17.11 What are the Secretary's...

Utilities' ''obligation to serve'' under deregulation

International Nuclear Information System (INIS)

Alexander, C.B.

1997-01-01

The utility no longer has protected status, and the traditional franchise concept is under attack. Exclusive rights once conveyed to the utilities are being denied and not just in the area of gas sales. Exclusive rights once conveyed to utilities will be denied in more areas. State by state, the utilities' franchise is being examined to see which, if any, of its provisions are necessary in a deregulated environment. Can the free market provide everything that's been provided for many years under monopolistic arrangements? Some of the most critical and difficult of these provisions concern the obligation to serve, which utilities, in most states, have assumed as part of their franchise agreement. Regulators, courts, utilities, marketers and others are busy sorting through these issues, but resolution could take years. The paper discusses deregulation, universal service fee, representation without taxation, suppliers and marketer restrictions

Oxygen-dependent growth of the obligate anaerobe Desulfovibrio vulgaris Hildenborough.

OpenAIRE

Johnson, M S; Zhulin, I B; Gapuzan, M E; Taylor, B L

1997-01-01

Desulfovibrio vulgaris Hildenborough, a sulfate-reducing bacterium classified as an obligate anaerobe, swam to a preferred oxygen concentration of 0.02 to 0.04% (0.24 to 0.48 microM), a level which also supported growth. Oxygen concentrations of 0.08% and higher arrested growth. We propose that in zones of transition from an oxic to an anoxic environment, D. vulgaris protects anoxic microenvironments from intrusion of oxygen.

18 CFR 1314.4 - Law governing the rights and obligations of TVA and Reserve Banks; law governing the rights of...

Science.gov (United States)

2010-04-01

... rights and obligations of TVA and Reserve Banks; law governing the rights of any Person against TVA and... FEDERAL RESERVE BANKS § 1314.4 Law governing the rights and obligations of TVA and Reserve Banks; law governing the rights of any Person against TVA and Reserve Banks; law governing other interests. (a) Except...

The Law Applicable to Contractual Obligations: The Rome I Regulation in Comparative Perspective

OpenAIRE

De Miguel Asensio, Pedro Alberto

2014-01-01

The Law Applicable to Contractual Obligations: The Rome I Regulation in Comparative Perspective I. Introduction II. Party Autonomy III. Applicable Law in the Absence of Choice IV. Protection of Weaker Parties V. Overriding Mandatory Rules and Public Policy

76 FR 81421 - Eligible Obligations, Charitable Contributions, Nonmember Deposits, Fixed Assets, Investments...

Science.gov (United States)

2011-12-28

.... We may not consider comments received after the above date in making our decision on the proposed... (FCUs) because they would no longer need to engage in any process for a RegFlex designation. In addition... provides an additional flexibility by specifically authorizing the purchase of obligations from federally...

One after the other : Effects of sequence patterns of breaches and overfulfilled obligations

NARCIS (Netherlands)

de Jong, Jeroen; Rigotti, Thomas; Mulder, J.

2017-01-01

To date, the study of psychological contracts has primarily centred on the question how retrospective evaluations of the psychological contract impact employee attitudes and behaviours, and/or focus on individual coping processes in explaining responses to breached or overfulfilled obligations. In

42 CFR 64a.105 - What are the conditions of obligated service?

Science.gov (United States)

2010-10-01

... under the Mental Health Systems Act or the Community Mental Health Centers Act; (iii) A psychiatric... FELLOWSHIPS, INTERNSHIPS, TRAINING OBLIGATED SERVICE FOR MENTAL HEALTH TRAINEESHIPS § 64a.105 What are the... alcohol, drug abuse or mental health services to one or more of the priority population groups listed in...

The reform of the French Law of Obligations: les jeux sont faits

NARCIS (Netherlands)

Smits, Jan; Calomme, Caroline

2016-01-01

1 October 2016 was a historic date for French law. For the first time since the introduction of the French Civil Code in 1804, a fundamental reform of the codified law of obligations took place. This contribution discusses both the motives for and the contents of this reform. Particular attention is

77 FR 31981 - Eligible Obligations, Charitable Contributions, Nonmember Deposits, Fixed Assets, Investments...

Science.gov (United States)

2012-05-31

... not consider comments received after the above date in making any decision whether to amend the... federal credit unions (FCUs) because they will no longer need to engage in any process for a RegFlex... specifically authorizing the purchase of obligations from federally insured credit unions beyond those an FCU...

Legal Responsibilities and Contractual Obligations Imposed on a University by Its Catalog.

Science.gov (United States)

Peterson, Erlend D.

The college catalog is discussed with regard to its contractual obligations and applicable federal legislation, and court cases are examined. Historical developments, elements of a contract, and student rights are also addressed. It is suggested that although the university is contractually bound by its published policies and procedures, it can…

Satisfaction, discomfort, obligations, and concerns in population-based breast cancer screening: cross-sectional study in a Danish population.

Science.gov (United States)

Gabel, Pernille; Larsen, Mette Bach; Nielsen, Pernille Bjørnholt; Svendstrup, Dorte Brandt; Andersen, Berit

2017-07-14

Potential barriers to breast cancer screening adherence include patient satisfaction, as well as pain, feeling obliged to participate, and other concerns that might compromise the level of satisfaction. The present study aimed to assess the overall satisfaction of Danish citizens with their breast cancer screening experiences, as well as their level of discomfort, concerns, and feelings of obligation to participate. Furthermore, we analyzed the associations between overall satisfaction and the remaining outcomes. Questionnaires were mailed to 3000 women in the Central Denmark Region who received screening examination results in the fall of 2013. The questionnaire assessed satisfaction (overall, telephone hot-line, and web-based self-service), discomfort (pain and boundaries of modesty), concerns (at invitation, while waiting for results, and after receiving results), and feelings of obligation to participate. Background information was retrieved from Statistics Denmark. Pearson's chi-square test was used to test differences in outcomes and demographic characteristic distributions between respondents and non-respondents and highly satisfied vs. less satisfied participants. Prevalence ratios (PR) with 95% CI were assessed using Poisson regression with robust variance, to estimate associations between satisfaction and the remaining outcomes. Among the participants, 70.3% and 29.4%, respectively, reported really good and good impressions of the screening program. Lower satisfaction was associated with feeling pain (prevalence ratio (PR), 0.82), feeling that modesty boundaries were transgressed (PR, 0.79), experiencing screening-induced concerns (PR, 0.84), and feeling obliged to participate (PR, 0.96). Of the participants, 36.2% and 12.9%, respectively, felt very much and moderately obliged to participate. A total of 72.6% reported no screening-induced concerns, including 73.3% of those with negative screening results and 38.1% of those with positive screening results

Study of obligations defined in agreements between parties involved in clinical trials of medicinal products in Bulgaria.

Science.gov (United States)

N Getov, Ilko; Gocheva-Hristova, Tanya; Lebanova, Hristina V; Grigorov, Evgeni E

2012-08-01

To analyse and assess the legislative and contractual obligations of the parties involved in the conduct of clinical trials, with identification of the needs for comprehensive contractual regulation of their rights and responsibilities. This survey has been carried out by means of review, analysis of comprehensiveness, comparative legislative analysis and assessment of compliance with the legislation of sample of investigator and site agreements governing the process of conducting clinical trials. The survey comprises analyses of contractual relations between the sponsor of the study and the investigator, and between the sponsor of the study and the trial site, respectively, relevant to clinical trials which are actually conducted in Bulgaria at the time of and following the survey. Comparative method based on pre-defined structured indices was employed to outline the major variances in the volume of responsibilities and obligations of the said parties to the clinical trial, as regulated by the investigator and site agreements. The analysis of comprehensiveness showed evident omissions in the regulation of relations and interactions between the parties to the agreements. The detailed contractual regulation providing for the statutory obligations and responsibilities of the parties involved in the conduct of clinical trials is a good guarantee for proper understanding of the obligations of each party and for compliance with their relevant responsibilities in view of protecting the rights of the participants in the clinical trials - patients or healthy volunteers.

[Modification of the Hungate vessel for cultivation of facultative and obligate anaerobic bacteria].

Science.gov (United States)

Chernyshenko, D V

2000-01-01

Modified Hungate vessel made of native penicillinum bottles and chemical vessels has been created and experimentally studied. The vessels can be used for cultivation of facultative and obligate anaerobe microorganisms on liquid and solid nutrient media. Locking devices of the vessel are described.

77 FR 7108 - Affirmative Action and Nondiscrimination Obligations of Contractors and Subcontractors Regarding...

Science.gov (United States)

2012-02-10

... DEPARTMENT OF LABOR Office of Federal Contract Compliance Programs 41 CFR Part 60-741 RIN 1250-AA02 Affirmative Action and Nondiscrimination Obligations of Contractors and Subcontractors Regarding Individuals With Disabilities AGENCY: Office of Federal Contract Compliance Programs, Labor. ACTION: Notice of...

76 FR 36482 - Affirmative Action and Nondiscrimination Obligations of Contractors and Subcontractors Regarding...

Science.gov (United States)

2011-06-22

... DEPARTMENT OF LABOR Office of Federal Contract Compliance Programs 41 CFR Parts 60-250 and 60-300 RIN 1250-AA00 Affirmative Action and Nondiscrimination Obligations of Contractors and Subcontractors Regarding Protected Veterans AGENCY: Office of Federal Contract Compliance Programs, Labor. ACTION: Notice...

'Candidatus pasteuria usgae' sp. nov., an obligate endoparasite of the phytoparasitic nematode Belonolaimus longicaudatus.

Science.gov (United States)

Giblin-Davis, R M; Williams, D S; Bekal, S; Dickson, D W; Brito, J A; Becker, J O; Preston, J F

2003-01-01

Taxonomically relevant characteristics of a fastidiously Gram-positive, obligately endoparasitic prokaryote (strain S-1) that uses the phytoparasitic sting nematode Belonolaimus longicaudatus as its host are reviewed. 16S rDNA sequence similarity (> or = 93%) confirms its congeneric ranking with other Pasteuria species and strains from nematodes and cladocerans and corroborates morphological, morphometric and host range evidence suggesting a novel taxon. The 16S rDNA sequence of strain S-1 has greatest similarity (96%) to the 16S rDNA sequences of both Pasteuria penetrans from root-knot nematodes (Meloidogyne species) and the recently reported strain of Pasteuria isolated from the soybean cyst nematode Heterodera glycines. Because the obligately endoparasitic nature of prokaryotes in the genus Pasteuria prevents isolation of definitive type strains, strain S-1 is proposed as 'Candidatus Pasteuria usgae' sp. nov.

Expectations of filial obligation and their impact on preferences for future living arrangements of middle-aged and older Asian Indian immigrants.

Science.gov (United States)

Diwan, Sadhna; Lee, Sang E; Sen, Soma

2011-03-01

Filial obligation, described as culturally-defined rights and duties that prescribe how family members are expected to care for and provide support to each other, is an important variable that influences older immigrants' preferences for living and care arrangements. This exploratory study examined variables associated with expectations of filial obligation among middle-aged and older, Asian Indian, first generation immigrants and explored the relationship between variations in expectations of filial obligation and expressed preferences for future living arrangements. Data were collected through telephone surveys of 226 English-speaking immigrants in Atlanta, GA. Although no significant relationships were observed between filial obligation expectations and length of residence in the U.S., respondents indicated a variety of preferred future living arrangements. Contrary to current living arrangement patterns found among older immigrants, very few respondents preferred to move in with their children. The most popular preference was to "move closer to children," followed by "moving to a retirement community" with the majority preferring a retirement community geared to Asian Indians. Other preferences included "not moving" and "returning to India." Variations in expectations of filial obligation, length of residence in the U.S., and self-rated health were significantly associated with these preferences. Implications are discussed for building capacity within ethnic communities to address living arrangement preferences and their repercussions for caregiving in ethnic families and in communities.

Warranty obligations for the management and underground disposal of radioactive waste

International Nuclear Information System (INIS)

Jauho, P.; Silvennoinen, P.

1980-01-01

The need for financial assurances and institutional arrangements for waste management and disposal is discussed from the viewpoint of public interest. The basic principles stated in the paper include the requirement of accumulating funds for future contingencies during the active lifetime of the reactors and the fuel cycle facilities. A governmental role is seen as indispensable in assuming responsibility over at least the surveillance of underground repositories. The stage at which the operational responsibility is transferred from the plant operator to the government is determined in general by the status of the waste conditioning and disposal technology. A brief survey is presented of the current situation and technical issues.The need for special funds is discussed as well. For the part of waste management and disposal that will be taken over by the government an escrow fund should be established. Parallel to this public fund the plant operator would be obliged to reserve funds and provide guarantees within the company to cover liabilities for the remaining part of waste management and disposal obligations. A case study is presented in the paper covering the estimation of the escrow charges for spent fuel or high-level waste. (author)

Community liberalisation of the electric power market and public service obligations

International Nuclear Information System (INIS)

Cristoforetti, Brice

2008-06-01

After an overview of original economic and social objectives at the basis of the creation of the European common market, the author examines whether the Community liberalisation of the European domestic electricity market has been an opportunity to acknowledge public service obligations in the European law, and more particularly examines the existence or relevance of the notion of electric power public service. This discussion addresses a period extending from the beginning of the 1960's to the Lisbon Treaty prepared in 2007. The author analyses rules of the European law, and the modalities and consequences of their adoption in the French law, as he considers that the evolution of French administrative legal evolution is the most relevant framework for this study on public service and electric power market. Thus, he first shows that the sector liberalisation, through the conflict between competition and defence of the general interest, actually allowed the existence of public service obligations for State members to be consecrated by the Community law. However, through the study of the electric power public service, the author shows that ambitions which had been initially put forward, are hardly compatible with some modalities of opening to competition

Unliquidated Obligations for Air Force-Funded Projects Administered by The Naval Facilities Engineering Command

National Research Council Canada - National Science Library

2001-01-01

... consolidated financial statements. The Air Force Audit Agency requested us to assist in its review of the Statement of Budgetary Resources for the Air Force General Fund by reviewing unliquidated obligations for Air Force-funded...

Minamata Convention on Mercury. Reporting obligations of the Parties to the Convention and the sources of data existing in Poland

Directory of Open Access Journals (Sweden)

Strzelecka-Jastrząb Ewa

2018-01-01

Full Text Available After that, when more than 60 years ago in the Japanese city of Minamata there was caused a mass poisoning of residents by seafood contaminated with mercury, Minamata Convention on Mercury came into force on August 16, 2017. To date, the Convention has been signed by 128 States, the signatories of the Convention and ratified by 83 States - Parties to the Convention. The Convention imposes a number of obligations on the Parties to the Convention, including the reporting obligation. The paper analyses the reporting obligations of the Parties to the Convention, which are in force after the entry into force of the Convention, pursuant to the provisions contained therein. In addition, the existing sources of quantitative data on mercury in Poland are characterized.

Balancing work and family obligations in Pakistan and the Netherlands : A comparative study

NARCIS (Netherlands)

Syed, S.; Arain, G.A.; Schalk, Rene; Freese, C.

2015-01-01

A study of 486 banking employees in Pakistan and the Netherlands investigated the effect of work-family conflict on psychological contract breach of work-family balance obligations. The results showed that 127 Dutch respondents were more likely to experience work interference with family than

28 CFR 30.11 - What are the Attorney General's obligations in interstate situations?

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false What are the Attorney General's... INTERGOVERNMENTAL REVIEW OF DEPARTMENT OF JUSTICE PROGRAMS AND ACTIVITIES § 30.11 What are the Attorney General's obligations in interstate situations? (a) The Attorney General is responsible for: (1) Identifying proposed...

76 FR 49477 - Termination of Federal Home Loan Bank Resolution Funding Corporation Obligation

Science.gov (United States)

2011-08-10

... FEDERAL HOUSING FINANCE AGENCY [No. 2011-N-08] Termination of Federal Home Loan Bank Resolution... Banks (Banks) have satisfied their statutory obligation to contribute a percentage of their annual net earnings toward the interest payments due on bonds issued by the Resolution Funding Corporation (RefCorp...

Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites

KAUST Repository

Woo, Yong

2015-07-15

The eukaryotic phylum Apicomplexa encompasses thousands of obligate intracellular parasites of humans and animals with immense socio-economic and health impacts. We sequenced nuclear genomes of Chromera velia and Vitrella brassicaformis, free-living non-parasitic photosynthetic algae closely related to apicomplexans. Proteins from key metabolic pathways and from the endomembrane trafficking systems associated with a free-living lifestyle have been progressively and non-randomly lost during adaptation to parasitism. The free-living ancestor contained a broad repertoire of genes many of which were repurposed for parasitic processes, such as extracellular proteins, components of a motility apparatus, and DNA- and RNA-binding protein families. Based on transcriptome analyses across 36 environmental conditions, Chromera orthologs of apicomplexan invasion-related motility genes were co-regulated with genes encoding the flagellar apparatus, supporting the functional contribution of flagella to the evolution of invasion machinery. This study provides insights into how obligate parasites with diverse life strategies arose from a once free-living phototrophic marine alga. © Woo et al.

Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites

KAUST Repository

Woo, Yong; Ansari, Hifzur Rahman; Otto, Thomas D.; Linger, Christen M K; Olisko, Martin K.; Michá lek, Jan; Saxena, Alka; Shanmugam, Dhanasekaran; Tayyrov, Annageldi; Veluchamy, Alaguraj; Ali, Shahjahan; Bernal, Axel; Del Campo, Javier; Cihlá ř, Jaromí r; Flegontov, Pavel; Gornik, Sebastian G.; Hajdušková , Eva; Horá k, Aleš; Janouškovec, Jan; Katris, Nicholas J.; Mast, Fred D.; Miranda-Saavedra, Diego; Mourier, Tobias; Naeem, Raeece; Nair, Mridul; Panigrahi, Aswini Kumar; Rawlings, Neil D.; Padron Regalado, Eriko; Ramaprasad, Abhinay; Samad, Nadira; Tomčala, Aleš; Wilkes, Jon; Neafsey, Daniel E.; Doerig, Christian; Bowler, Chris; Keeling, Patrick J.; Roos, David S.; Dacks, Joel B.; Templeton, Thomas J.; Waller, Ross F.; Lukeš, Julius; Oborní k, Miroslav; Pain, Arnab

2015-01-01

The eukaryotic phylum Apicomplexa encompasses thousands of obligate intracellular parasites of humans and animals with immense socio-economic and health impacts. We sequenced nuclear genomes of Chromera velia and Vitrella brassicaformis, free-living non-parasitic photosynthetic algae closely related to apicomplexans. Proteins from key metabolic pathways and from the endomembrane trafficking systems associated with a free-living lifestyle have been progressively and non-randomly lost during adaptation to parasitism. The free-living ancestor contained a broad repertoire of genes many of which were repurposed for parasitic processes, such as extracellular proteins, components of a motility apparatus, and DNA- and RNA-binding protein families. Based on transcriptome analyses across 36 environmental conditions, Chromera orthologs of apicomplexan invasion-related motility genes were co-regulated with genes encoding the flagellar apparatus, supporting the functional contribution of flagella to the evolution of invasion machinery. This study provides insights into how obligate parasites with diverse life strategies arose from a once free-living phototrophic marine alga. © Woo et al.

Coping with the Obligation Dilemma: Prototypes of Social Workers in the Nursing Home.

Science.gov (United States)

Lev, Sagit; Ayalon, Liat

2016-07-01

We examined the ways in which the social worker is coping with obligation dilemma in an Israeli nursing home. The research was conducted using semi-structured, in-depth interviews carried out with fifteen social workers employed in nursing homes. The interviews were analysed thematically, using constant comparisons. The three themes were concerned with the social worker's place in the nursing home, her relationship with the management and staff, and her coping with the obligation dilemma. These themes highlighted the difference between the interviewees. On the background of this difference, four prototypes of nursing home's social workers were defined: the managerial, the contented, the fighter and the frustrated. From analysing the findings, the significant place of the personal and environmental factors that influence the ways in which the social worker deals with these four themes emerges. Our findings suggest that the strengthening, empowerment and support of social workers in institutions can directly enhance the health, security, emotional well-being and quality of life of nursing home residents.

Modernizing international maintenance obligations in Serbia

Directory of Open Access Journals (Sweden)

Bordaš Bernadet

2013-01-01

Full Text Available The paper deals with the modernization of private international law of maintenance in Serbia in the light of the two newest international instruments drawn up by the Hague Conference on Private International Law. As Serbia has ratified the Hague Protocol on the Law Applicable to Maintenance Obligations in January 2013 introducing modern rules to the legal system of Serbia, the issue of ratification of the Hague Convention on the International Recovery of Child Support and Other Forms of Family Maintenance has arisen, in order to modernize this aspect of the international maintenance as well. In order to establish a position on the issue, the paper presents and analyzes the essential provisions of the Convention (scope of application, administrative cooperation, recognition and enforcement of decisions, stricto sensu enforcement. Based on the analyses, the concluding remarks offers some elements on the bases of which the competent authorities could form an opinion on the necessity and desirability of the ratification of the Convention.

Legal regulation of the obligations in old romanian law, greek and roman

Directory of Open Access Journals (Sweden)

Ion Tutuianu

2012-12-01

Full Text Available Legal history shows that those who are defined obligation Romans definition valid today as a relationship as we submit to a benefit from a third party. Their importance lies in the fact that although rooted in ancient as it spread in all legal systems, across time and still keeping the same legal and economic importance.

Real-Time Molecular Monitoring of Chemical Environment in ObligateAnaerobes during Oxygen Adaptive Response

Energy Technology Data Exchange (ETDEWEB)

Holman, Hoi-Ying N.; Wozei, Eleanor; Lin, Zhang; Comolli, Luis R.; Ball, David. A.; Borglin, Sharon; Fields, Matthew W.; Hazen, Terry C.; Downing, Kenneth H.

2009-02-25

Determining the transient chemical properties of the intracellular environment canelucidate the paths through which a biological system adapts to changes in its environment, for example, the mechanisms which enable some obligate anaerobic bacteria to survive a sudden exposure to oxygen. Here we used high-resolution Fourier Transform Infrared (FTIR) spectromicroscopy to continuously follow cellular chemistry within living obligate anaerobes by monitoring hydrogen bonding in their cellular water. We observed a sequence of wellorchestrated molecular events that correspond to changes in cellular processes in those cells that survive, but only accumulation of radicals in those that do not. We thereby can interpret the adaptive response in terms of transient intracellular chemistry and link it to oxygen stress and survival. This ability to monitor chemical changes at the molecular level can yield important insights into a wide range of adaptive responses.

Obligations and responsibilities in radiation protection in the medical field

International Nuclear Information System (INIS)

2011-01-01

This document briefly presents the various obligations and responsibilities of the various actors involved in or concerned by radiation protection in the medical field: the hospital administration (with respect to workers and patients), the physician (authorization and declaration, justification, optimization), the medical electro-radiology operator, the person with expertise in medical radio-physics (PSRPM), the radio-pharmacist (he is required in nuclear medicine with internal use of pharmaceutical product), the personnel with expertise in radiation protection (PCR), and other health professionals

Biolistic transformation of the obligate plant pathogenic fungus, Erysiphe graminis f.sp. hordei

DEFF Research Database (Denmark)

Christiansen, S.K.; Knudsen, S.; Giese, H.

1995-01-01

Particle gun acceleration appears to be a possible way to transform mycelium cells of obligate plant parasites growing on host surfaces, GUS expression was obtained in E. graminis f.sp. hordei cells after bombardment with the GUS gene under the control of the E. graminis f.sp. hordei beta...

Implementation of State Obligations and Responsibility Ensuring the Availability of Clean Water in Karimunjawa Islands

Science.gov (United States)

Rahayu; Soeprobowati, Tri Retnaningsih

2018-02-01

This article aims to analyze the implementation of state obligations and responsibility ensuring the availability of clean water as part of human rights in Karimunjawa islands. The analysis based on principle of the State obligations and responsibility to fulfill their citizen right. Water sources in Karimunjawa Islands is very limited. It depend on forest conservation. Around 9.600 peoples live in Karimunjawa Islands, but Karimunjawa is non groundwater basin region. It means, Karimunjawa doesn't have groundwater potential. The quantity of water depends on the season. The solution to maintain the sustainability of clean water is piping from water reservoir to residential areas. The problem is there are so many hotels in Karimunjawa islands, it disrupted the fulfillment of clean water. Besides utilizing water from reservoir, many hotels drilled the ground to get water. It had impact to the availibity of water in dry season and affected to fulfillment of water supply for Karimunjawa people. There is no specific regulation and policy to solve this problem. Clean water management is doing by Karimunjawa's people. Meanwhile, based on Mahkamah Konstitusi Decree number 85/PUU-XI/2013, state is a rights holder to dominate the water in accordance with the Articles 33 paragraph (2) and (3) UUD NRI 1945, so the government has an obligation to make a policy, regulations, management, and supervision.

An obligately aerobic soil bacterium activates fermentative hydrogen production to survive reductive stress during hypoxia.

Science.gov (United States)

Berney, Michael; Greening, Chris; Conrad, Ralf; Jacobs, William R; Cook, Gregory M

2014-08-05

Oxygen availability is a major factor and evolutionary force determining the metabolic strategy of bacteria colonizing an environmental niche. In the soil, conditions can switch rapidly between oxia and anoxia, forcing soil bacteria to remodel their energy metabolism accordingly. Mycobacterium is a dominant genus in the soil, and all its species are obligate aerobes. Here we show that an obligate aerobe, the soil actinomycete Mycobacterium smegmatis, adopts an anaerobe-type strategy by activating fermentative hydrogen production to adapt to hypoxia. This process is controlled by the two-component system DosR-DosS/DosT, an oxygen and redox sensor that is well conserved in mycobacteria. We show that DosR tightly regulates the two [NiFe]-hydrogenases: Hyd3 (MSMEG_3931-3928) and Hyd2 (MSMEG_2719-2718). Using genetic manipulation and high-sensitivity GC, we demonstrate that Hyd3 facilitates the evolution of H2 when oxygen is depleted. Combined activity of Hyd2 and Hyd3 was necessary to maintain an optimal NAD(+)/NADH ratio and enhanced adaptation to and survival of hypoxia. We demonstrate that fermentatively-produced hydrogen can be recycled when fumarate or oxygen become available, suggesting Mycobacterium smegmatis can switch between fermentation, anaerobic respiration, and aerobic respiration. Hydrogen metabolism enables this obligate aerobe to rapidly meet its energetic needs when switching between microoxic and anoxic conditions and provides a competitive advantage in low oxygen environments.

Hong Kong Chinese daughters' intergenerational caregiving obligations: a cultural model approach.

Science.gov (United States)

Holroyd, E

2001-11-01

This paper, based on a study carried out in Hong Kong, outlines the caregiving obligations of Hong Kong Chinese daughters towards their frail elderly parents. A cultural model approach drawn from cognitive anthropology is taken to focus on how Chinese caregiving daughters develop a sense of what is right and emotionally fulfilling and acquire the motivation to care for their parents. An ethnographic approach was used in the study and techniques included guided and open-ended interviews and non-participatory observations. A total of 20 co-residential caregiving daughters were interviewed in their homes on average twice over the course of one year. All interviews were conducted in Cantonese. Although the sample was small, daughters' accounts are structured by reference to cultural models and this structure provides the common basis for generalisability of results. Concepts of Confucian antecedents, reciprocity and personhood and other modern ideas of filial duty are explored. Conclusions are drawn about the shifting rights and obligations of Chinese caregiving daughters within the contemporary urban realities of Hong Kong. The findings of this study have relevance for the development of welfare policy for older Chinese persons and the chronically ill, and to all services involving women. The findings will also serve to inform family caregiver education programs.

Consequences of reductive evolution for gene expression in an obligate endosymbiont.

Science.gov (United States)

Wilcox, Jennifer L; Dunbar, Helen E; Wolfinger, Russell D; Moran, Nancy A

2003-06-01

The smallest cellular genomes are found in obligate symbiotic and pathogenic bacteria living within eukaryotic hosts. In comparison with large genomes of free-living relatives, these reduced genomes are rearranged and have lost most regulatory elements. To test whether reduced bacterial genomes incur reduced regulatory capacities, we used full-genome microarrays to evaluate transcriptional response to environmental stress in Buchnera aphidicola, the obligate endosymbiont of aphids. The 580 genes of the B. aphidicola genome represent a subset of the 4500 genes known from the related organism, Escherichia coli. Although over 20 orthologues of E. coli heat stress (HS) genes are retained by B. aphidicola, only five were differentially expressed after near-lethal heat stress treatments, and only modest shifts were observed. Analyses of upstream regulatory regions revealed loss or degradation of most HS (sigma32) promoters. Genomic rearrangements downstream of an intact HS promoter yielded upregulation of a functionally unrelated and an inactivated gene. Reanalyses of comparable experimental array data for E. coli and Bacillus subtilis revealed that genome-wide differential expression was significantly lower in B. aphidicola. Our demonstration of a diminished stress response validates reports of temperature sensitivity in B. aphidicola and suggests that this reduced bacterial genome exhibits transcriptional inflexibility.

24 CFR 811.110 - Refunding of obligations issued to finance Section 8 projects.

Science.gov (United States)

2010-04-01

... finance Section 8 projects. 811.110 Section 811.110 Housing and Urban Development Regulations Relating to... RELATED AMENDMENTS § 811.110 Refunding of obligations issued to finance Section 8 projects. (a) This... refunding which generate the McKinney Act savings and, if necessary, HUD will finance in refunding bond debt...

BRIEF CONSIDERATIONS REGARDING THE PROPERTY TRANSFERRING OR ENGENDERING OF OBLIGATIONS CHARACTER OF THE SALES CONTRACT

Directory of Open Access Journals (Sweden)

Vlad-Victor OCHEA

2016-05-01

Full Text Available I herein want to emphasize the main aspects regarding the property/real estate transferring or engendering of obligations character of the sales contract governed by the Romanian Civil Code of 2009.

Financial conflicts of interest and the ethical obligations of medical school faculty and the profession.

Science.gov (United States)

Austad, Kirsten; Brendel, David H; Brendel, Rebecca W

2010-01-01

Despite their potential benefits, relationships linking medical school faculty and the pharmaceutical and device industries may also challenge the professional value of primacy of patient welfare, a point highlighted in a recent Institute of Medicine report. Academic medical centers and professors have the added professional obligation to ensure the unbiased, evidence-based education of future doctors. This essay argues that faculty financial conflicts of interest may threaten this obligation by propagating the bias introduced by these relationships to students. This could occur directly through the process of curriculum determination and delivery, and also indirectly through the "hidden curriculum," which deserves particular attention, as its lessons may conflict with those professed in the formal curriculum. The essay concludes with guiding principles to consider when developing a conflict of interest policy at academic medical centers.

Overview of the IAEA Joint Convention and Implementation Status of the Obligation as the Contracting Party of the 5th Joint Convention

International Nuclear Information System (INIS)

Lee, Jeong Ken; Lee, Youn Keun; Ahn, Sang Myeon

2016-01-01

The Joint Convention on the Safety of Spent Fuel Management and on the Safety of Radioactive Waste Management (Joint Convention) was adopted on 5 September 1997 by a Diplomatic Conference convened by the International Atomic Energy Agency (IAEA). The Joint Convention was opened for signature at Vienna in September 1997 and will remain open for signature until its entry into force. Korean government signed the Joint Convention in 1997 and this Convention was effective in 2002 as the Convention No. 1612. This paper will show overview of the Joint Convention and implementation status of the obligation as a Contracting Party of the 5th Joint Convention. The Joint Convention is the inter-national convention organized by the IAEA. All contracting parties shall comply with rules of the Joint Convention and conduct the obligation of this convention. Korean government successfully conducted all obligation (attending Organization Meeting and Review Meeting, submitting paper including National Report, question paper and answer paper) of the 5th Joint Convention from May 2014 to May 2015, and will prepare the obligation of the 6th Joint Convention

The Pricing puzzle: The default term structure of collateralised loan obligations

OpenAIRE

Jobst, Andreas A.

2002-01-01

Ambivalence in the regulatory definition of capital adequacy for credit risk has recently stirred the financial services industry to collateral loan obligations (CLOs) as an important balance sheet management tool. CLOs represent a specialised form of Asset-Backed Securitisation (ABS), with investors acquiring a structured claim on the interest proceeds generated from a portfolio of bank loans in the form of tranches with different seniority. By way of modelling Merton-type risk-neutral asset...

26 CFR 1.453-9 - Gain or loss on disposition of installment obligations.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 6 2010-04-01 2010-04-01 false Gain or loss on disposition of installment...-9 Gain or loss on disposition of installment obligations. (a) In general. Subject to the exceptions contained in section 453(d)(4) and paragraph (c) of this section, the entire amount of gain or loss...

Attitudes toward Family Obligations among American Adolescents with Asian, Latin American, and European Backgrounds.

Science.gov (United States)

Fuligni, Andrew J.; Tseng, Vivian; Lam, May

1999-01-01

Examined attitudes toward family obligations in American tenth and twelfth graders from Filipino, Chinese, Mexican, Central and South American, and European backgrounds. Found that even within a society emphasizing adolescent autonomy and independence, youths from families with collectivistic traditions retain their parents' familial values and…

Revisiting the theoretical basis of the endosymbiotic origin of plastids in the original context of Lynn Margulis on the origin of mitosing, eukaryotic cells.

Science.gov (United States)

Sato, Naoki

2017-12-07

Fifty years ago, Lynn Margulis proposed a comprehensive hypothesis on the origin of eukaryotic cells with an emphasis on the origin of mitosis. This hypothesis postulated that the eukaryotic cell is a composite of different parts as a result of the symbiosis of various different bacteria. In this hypothesis, she integrated previously proposed ideas that mitochondria and chloroplasts were descendants of endosymbionts that originated from aerobic bacteria and blue-green algae (now cyanobacteria), respectively. However, the major part of her hypothesis, which she believed to be original, was the origin of mitosis. The core of her postulate involved a chromosome partition mechanism dependent on DNA-microtubule binding, which originated from a hypothetical centriole-DNA complex, with an ability to replicate. Surprisingly, her complete lack of real experimental works in the cytoskeleton, cell motility, or paleontology did not prevent this 29-year-old junior scientist from assembling archival knowledge and constructing a narrative on the evolution of all organisms. Whether the centriole-DNA complex originated from a spirochete or not was a minor anecdote in this initial postulate. Unfortunately, this hypothesis on the origin of mitosis, which she believed to be a holistic unity, testable by experiments, was entirely refuted. Despite falsification of her original narrative as a whole, her success as a founder of endosymbiotic theory on the origin of mitochondria and chloroplasts is undoubted. We will discuss the reasons for her success in terms of the historical situation in the latter half of the 20th century. Copyright © 2017 Elsevier Ltd. All rights reserved.

[Characteristic of clinical strains of gram-negative obligate anaerobes].

Science.gov (United States)

Kadzielska, Joanna; Kierzkowska, Marta; Sawicka-Grzelak, Anna; Rokosz, Alicja; Łuczak, Mirosław

2007-01-01

The aim of the study was to assess prevalence and antibiotic susceptibility profiles ofGram-negative strictly anaerobic bacteria isolated from clinical specimens taken from hospitalized patients in 2005-2006. Biochemical identification and antibiotic susceptibility were done in an automated system ATB Expression (bioMerieux sa). From 12262 specimens examined 867 strains of obligate anaerobes were isolated. Gram-negative strictly anaerobic bacteria were cultured in number of 138 strains (15,9%). All cultures were performed on Columbia agar and Schaedler agar media (bioMerieux sa) supplemented with 5% sheep blood and incubated at 37 degrees C for 48-120 h in 85% N2, 10% H2, 5% CO2. Most frequently isolated was Bacteroides spp. (41,3%). For this group beta-lactamase activity was evaluated by using nitrocefin disc test (Cefinase BBL, Becton Dickinson and Co., Cockeysville, MD, USA). Production of ESBLs was detected with the use of two disc diffusion methods: the double-disc synergy test (DDST) according to Jarlier et al. and the diagnostic disc (DD) test according to Appleton. ESBLs were produced by 5,3% strains of Bacteroides spp. For all Bacteroides spp. strains MIC values were determined by gradient diffusion method Etest (AB BIODISK, Sweden). ESBLs and MIC were performed on Wilkins-Chalgren solid medium supplemented with 5% sheep blood (Difco Lab., USA) and all plates were incubated at 35 degrees C for 48 hours in 85% N2, 10% H2, 5% CO2. Most Gram-negative obligate anaerobes isolated from clinical specimens are still susceptible to imipenem (100%), metronidazole (99,3%) and beta-lactam antibiotics with beta-lactamase inhibitors: piperacillin/tazobactam (99,3%), ticarcillin/clavulanate (99.3%), amoxicillin/clavulanate (97.8%).

Photosynthesis of amphibious and obligately submerged plants in CO2-rich lowland streams.

Science.gov (United States)

Sand-Jensen, Kaj; Frost-Christensen, Henning

1998-11-01

Small unshaded streams in lowland regions receive drainage water with high concentrations of free␣CO 2 , and they support an abundant growth of amphibious and obligately submerged plants. Our first objective was to measure the CO 2 regime during summer in a wide range of small alkaline Danish streams subject to wide variation in temperature, O 2 and CO 2 during the day. The second objective was to determine the effect of these variations on daily changes in light-saturated photosynthesis in water of a homophyllous and a heterophyllous amphibious species that only used CO 2 , and an obligately submerged species capable of using both HCO - 3 and CO 2 . We found that the median CO 2 concentrations of the streams were 11 and 6 times above air saturation in the morning and the afternoon, respectively, but stream sites with dense plant growth had CO 2 concentrations approaching air saturation in the afternoon. In contrast, outlets from lakes had low CO 2 concentrations close to, or below, air saturation. The amphibious species showed a reduction of photosynthesis in water from morning to afternoon along with the decline in CO 2 concentrations, while increasing temperature and O 2 had little effect on photosynthesis. Photosynthesis of the obligately submerged species varied little with the change of CO 2 because of HCO 3 - - use, and variations were mostly due to changes in O 2 concentration. Independent measurements showed that changes in temperature, O 2 and CO 2 could account for the daily variability of photosynthesis of all three species in water. The results imply that CO 2 supersaturation in small lowland streams is important for the rich representation of amphibious species and their contribution to system photosynthesis.

The {open_quotes}obligation to serve{close_quotes} and a competitive electric industry

Energy Technology Data Exchange (ETDEWEB)

Colton, R.D. [Fisher, Sheehan and Colton (United States)

1997-11-01

This report presents an assessment of what the ``obligation to serve`` might look like in a competitive electric industry. Broadly, this research has three objectives: to define the ``duty to serve`` of a competitive electric industry; to identify those companies to whom that duty applies; and to explain how that duty protects residual classes.

Service and obligations of public service in the electrical sector law; Servicio universal y obligaciones de servicio publico en la Ley del Sector Electrico

Energy Technology Data Exchange (ETDEWEB)

Cuetara Martinez, J.M. de la; Gonzalez Sanfiel, A.

1998-12-01

Our article starts from the need of reconsidering the traditional public service concept; to this goal, the new categories universal service and public service obligations are useful instruments. After defining its notes, we identify them as different kinds of a common gender and separate then from other next categories, as are general interest services and policy obligations. Finally, we applied the obtained findings to the Electricity Sector, identifying an universal service in the supply of electrical energy to all the claimants and various concrete public service obligations in its principal sub sectors (production, transportation, distribution, trading and supply). (Author)

Strengthening of Organizational Infrastructure for Meeting IAEA Nuclear Safeguards Obligations: Bangladesh Perspective

International Nuclear Information System (INIS)

Mollah, A.S.

2010-01-01

Safeguards are arrangements to account for and control the use of nuclear materials. This verification is a key element in the international system which ensures that uranium in particular is used only for peaceful purposes. The only nuclear reactor in Bangladesh achieved critically on September 14, 1986. Reactor Operation and Maintenance Unit routinely carries out certain international obligations which need to undertake as signatory of different treaties, agreements and protocols in the international safeguards regime. Pursuant to the relevant articles of these agreements/protocols, the reactor and associated facilities of Bangladesh (Facility code: BDA- and BDZ-) are physically inspected by the designated IAEA safeguards inspectors. The Bangladesh Atomic Energy Commission (BAEC) has recently created a new division called 'Nuclear Safeguards and Security Division' for enhancing the safeguards activities as per international obligations. This division plays a leading role in the planning, implementation, and evaluation of the BAEC's nuclear safeguards and nuclear security activities. This division is actively working with USDOE, IAEA and EU to enhance the nuclear safeguards and security activities in the following areas: - Analysis of nuclear safeguards related reports of 3 MW TRIGA Mark-II research reactor; - Upgrading of physical protection system of 3 MW TRIGA Mark-II research reactor, gamma irradiation facilities, central radioactive storage and processing facility and different radiation oncology facilities of Bangladesh under GTRI programme; - Supervision for installation of radiation monitoring system of the Chittagong port under USDOE Megaports Initiative Programmes for detection of illicit trafficking of nuclear and radioactive materials; - Development of laboratory capabilities for analysis of nuclear safeguards related samples; - Planning for development of organizational infrastructure to carry out safeguards related activities under IAEA different

Multi locus sequence typing of Chlamydiales: clonal groupings within the obligate intracellular bacteria Chlamydia trachomatis

NARCIS (Netherlands)

Pannekoek, Yvonne; Morelli, Giovanna; Kusecek, Barica; Morré, Servaas A.; Ossewaarde, Jacobus M.; Langerak, Ankie A.; van der Ende, Arie

2008-01-01

BACKGROUND: The obligate intracellular growing bacterium Chlamydia trachomatis causes diseases like trachoma, urogenital infection and lymphogranuloma venereum with severe morbidity. Several serovars and genotypes have been identified, but these could not be linked to clinical disease or outcome.

Abrupt fire regime change may cause landscape-wide loss of mature obligate seeder forests.

Science.gov (United States)

Bowman, David M J S; Murphy, Brett P; Neyland, Dominic L J; Williamson, Grant J; Prior, Lynda D

2014-03-01

Obligate seeder trees requiring high-severity fires to regenerate may be vulnerable to population collapse if fire frequency increases abruptly. We tested this proposition using a long-lived obligate seeding forest tree, alpine ash (Eucalyptus delegatensis), in the Australian Alps. Since 2002, 85% of the Alps bioregion has been burnt by several very large fires, tracking the regional trend of more frequent extreme fire weather. High-severity fires removed 25% of aboveground tree biomass, and switched fuel arrays from low loads of herbaceous and litter fuels to high loads of flammable shrubs and juvenile trees, priming regenerating stands for subsequent fires. Single high-severity fires caused adult mortality and triggered mass regeneration, but a second fire in quick succession killed 97% of the regenerating alpine ash. Our results indicate that without interventions to reduce fire severity, interactions between flammability of regenerating stands and increased extreme fire weather will eliminate much of the remaining mature alpine ash forest. © 2013 John Wiley & Sons Ltd.

Secretome of obligate intracellular Rickettsia

Science.gov (United States)

Gillespie, Joseph J.; Kaur, Simran J.; Rahman, M. Sayeedur; Rennoll-Bankert, Kristen; Sears, Khandra T.; Beier-Sexton, Magda; Azad, Abdu F.

2014-01-01

The genus Rickettsia (Alphaproteobacteria, Rickettsiales, Rickettsiaceae) is comprised of obligate intracellular parasites, with virulent species of interest both as causes of emerging infectious diseases and for their potential deployment as bioterrorism agents. Currently, there are no effective commercially available vaccines, with treatment limited primarily to tetracycline antibiotics, although others (e.g. josamycin, ciprofloxacin, chloramphenicol, and azithromycin) are also effective. Much of the recent research geared toward understanding mechanisms underlying rickettsial pathogenicity has centered on characterization of secreted proteins that directly engage eukaryotic cells. Herein, we review all aspects of the Rickettsia secretome, including six secretion systems, 19 characterized secretory proteins, and potential moonlighting proteins identified on surfaces of multiple Rickettsia species. Employing bioinformatics and phylogenomics, we present novel structural and functional insight on each secretion system. Unexpectedly, our investigation revealed that the majority of characterized secretory proteins have not been assigned to their cognate secretion pathways. Furthermore, for most secretion pathways, the requisite signal sequences mediating translocation are poorly understood. As a blueprint for all known routes of protein translocation into host cells, this resource will assist research aimed at uniting characterized secreted proteins with their apposite secretion pathways. Furthermore, our work will help in the identification of novel secreted proteins involved in rickettsial ‘life on the inside’. PMID:25168200

[Facultative and obligate aerobic methylobacteria synthesize cytokinins].

Science.gov (United States)

Ivanova, E G; Doronina, N V; Shepeliakovskaia, A O; Laman, A G; Brovko, F A; Trotsenko, Iu A

2000-01-01

The presence and expression of genes controlling the synthesis and secretion of cytokinins by the pink-pigmented facultative methylotroph Methylobacterium mesophilicum VKM B-2143 with the serine pathway and nonpigmented obligate methylotroph Methylovorus mays VKM B-2221 with the ribulose monophosphate pathway of C1 metabolism were shown using the polymerase chain reaction (PCR) and reverse transcription-PCR methods. The presence of the corresponding mRNA in M. mesophilicum cells grown on methanol or succinate suggests that the expression of these genes is constitutive. The cytokinin activity of culture liquid and its fractions was determined by a biotest with Amarantus caudatus L. seedlings. Using enzyme-linked immunosorbent analysis, we detected zeatin (riboside) in the culture liquid of both bacteria studied. The data obtained show that the aerobic methylobacteria are phytosymbionts that are able to utilize the single- and polycarbon compounds secreted by symbiotic plants and to synthesize cytokinins.

48 CFR 819.7111 - Obligations under the Mentor-Protégé Program.

Science.gov (United States)

2010-10-01

... Mentor-Protégé Program. 819.7111 Section 819.7111 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS VA Mentor-Protégé Program 819.7111 Obligations under the Mentor-Protégé Program. (a) A mentor or protégé may voluntarily withdraw from the...

EXPLORING THE RELATIONSHIP BETWEEN CDS AND RATINGANNOUNCEMENTS: A LITERATURE REVIEW AND FUTURERESEARCH DIRECTIONS

Directory of Open Access Journals (Sweden)

Rosella Carè

2013-01-01

Full Text Available This paper proposes a systematic literature review for exploring the relationshipbetween CDS and rating announcements. To achieve this purpose, we haveisolated and explored the primary relevantfields in the literature and discussed thefindings. The value added of this preliminary work can be identified in the effortto identify new and promising research areas for future work.

47 CFR 25.278 - Additional coordination obligation for non-geostationary and geostationary satellite systems in...

Science.gov (United States)

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Additional coordination obligation for non-geostationary and geostationary satellite systems in frequencies allocated to the fixed-satellite service. 25.278 Section 25.278 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER...

20 CFR 726.207 - Discharge by the carrier of obligations and duties of operator.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Discharge by the carrier of obligations and duties of operator. 726.207 Section 726.207 Employees' Benefits EMPLOYMENT STANDARDS ADMINISTRATION, DEPARTMENT OF LABOR FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, AS AMENDED BLACK LUNG BENEFITS...

26 CFR 46.4701-1 - Tax on issuer of registration-required obligation not in registered form.

Science.gov (United States)

2010-04-01

.... (2) Obligation. The term “obligation” includes bonds debentures, notes, certificates and other... 10, 1982. See section 310(d)(3) of the Tax Equity and Fiscal Responsibility Act of 1982. [T.D. 8102...

The State’s obligation to protect the individuals lives from the consequences of domestic violence: Kosovo case

Directory of Open Access Journals (Sweden)

MSc. Vilard Bytyqi

2016-07-01

Full Text Available The aim of this paper is to treat the important aspects, which deal with State’s obligations to protect individuals’ lives from the consequences of the domestic violence. Thus, domestic violence is a concerning issue, which derives many consequences that sometimes are irreparable. In many cases, the State is obliged to save individuals’ lives from the effects of the domestic violence. The State will not be held responsible in all the cases for the consequences of the domestic violence. Due to the scarcity of the regulation of all the situations in the normative terms, the judicial practice that considers the cases of the right to live has evolved greatly, such that it has set many standards in case of increased institutional responsibility towards the consequences caused by the domestic violence. Due to a practical elaboration, the paper as such will focus in the treatment of cases from the judicial practice in the context of the State’s obligation to save individual’s life, whose life is endangered. Furthermore, there will also be an emphasis in the protection of the right to life and the State’s responsibility in relation to the consequences caused by the actions of the third parties.

Feeling Moral Obligation and Living in an Organic Unity: Virginia Woolf’s response to G. E. Moore

Directory of Open Access Journals (Sweden)

Rohini Shukla

2015-11-01

Full Text Available This paper explores the precise influence of Moore’s thought on Woolf’s novel To the Lighthouse. I begin with a brief exposition of Moore’s notion of ‘the good’ as experiencing moral obligation within an organic community. In doing so, I highlight a crucial loophole within his conceptual framework - he does not theorize the conditions for the possibility of experiencing moral obligation, and therefore renders the good ultimately ineffective in taking moral decisions. In the second section, drawing on Martin ?telf’s work, I read To the Lighthouse as conceptualising precisely the conditions for the possibility of moral obligation lacking in Moore’s framework, in explicitly epistemological terms - Mrs Ramsay’s ability to experience states of heightened perceptive intensity. Woolf thereby partakes in the anti-metaphysicalist and anti-naturalist rebellion characteristic of Moore’s ethical theory. In contrast to writers like Heidi Storl however, who consider Woolf’s works as mere literary embodiments or instantiations of what other ‘philosophers’ have said, I further argue that Woolf’s systematic philosophical intervention lies in the new kind of materialism she espouses, which is at once logically continuous with Moore’s realism and critical of the subject–object dichotomy he upholds.

77 FR 24252 - Notice of Release From Federal Grant Assurance Obligations for Sacramento International Airport...

Science.gov (United States)

2012-04-23

... Assurance Obligations for Sacramento International Airport (SMF), Sacramento, CA AGENCY: Federal Aviation... of land comprising approximately 6.50 acres of airport property at the Sacramento International Airport, California. The County of Sacramento proposes to release the 6.50 acres for sale to the...

40 CFR 29.5 - What is the Administrator's obligation with respect to Federal interagency coordination?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false What is the Administrator's obligation with respect to Federal interagency coordination? 29.5 Section 29.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL INTERGOVERNMENTAL REVIEW OF ENVIRONMENTAL PROTECTION AGENCY PROGRAMS AND...

The Development of Children's Ethnic Identity in Immigrant Chinese Families in Canada: The Role of Parenting Practices and Children's Perceptions of Parental Family Obligation Expectations

Science.gov (United States)

Su, Tina F.; Costigan, Catherine L.

2009-01-01

Parents' role in children's ethnic identity development was examined among 95 immigrant Chinese families with young adolescents living in Canada. Children reported their feelings of ethnic identity and perceptions of parental family obligation expectations. Parents reported their family obligation expectations; parents and children reported on…

Exometabolomics Assisted Design and Validation of Synthetic Obligate Mutualism.

Science.gov (United States)

Kosina, Suzanne M; Danielewicz, Megan A; Mohammed, Mujahid; Ray, Jayashree; Suh, Yumi; Yilmaz, Suzan; Singh, Anup K; Arkin, Adam P; Deutschbauer, Adam M; Northen, Trent R

2016-07-15

Synthetic microbial ecology has the potential to enhance the productivity and resiliency of biotechnology processes compared to approaches using single isolates. Engineering microbial consortia is challenging; however, one approach that has attracted significant attention is the creation of synthetic obligate mutualism using auxotrophic mutants that depend on each other for exchange or cross-feeding of metabolites. Here, we describe the integration of mutant library fitness profiling with mass spectrometry based exometabolomics as a method for constructing synthetic mutualism based on cross-feeding. Two industrially important species lacking known ecological interactions, Zymomonas mobilis and Escherichia coli, were selected as the test species. Amino acid exometabolites identified in the spent medium of Z. mobilis were used to select three corresponding E. coli auxotrophs (proA, pheA and IlvA), as potential E. coli counterparts for the coculture. A pooled mutant fitness assay with a Z. mobilis transposon mutant library was used to identify mutants with improved growth in the presence of E. coli. An auxotroph mutant in a gene (ZMO0748) with sequence similarity to cysteine synthase A (cysK), was selected as the Z. mobilis counterpart for the coculture. Exometabolomic analysis of spent E. coli medium identified glutathione related metabolites as potentially available for rescue of the Z. mobilis cysteine synthase mutant. Three sets of cocultures between the Z. mobilis auxotroph and each of the three E. coli auxotrophs were monitored by optical density for growth and analyzed by flow cytometry to confirm high cell counts for each species. Taken together, our methods provide a technological framework for creating synthetic mutualisms combining existing screening based methods and exometabolomics for both the selection of obligate mutualism partners and elucidation of metabolites involved in auxotroph rescue.

Safety Training: a right or an obligation?

CERN Multimedia

HSE Unit

2014-01-01

CERN’s Safety Training programme currently offers around 50 classroom courses and 17 e-learning courses. Although anyone can attend any of these courses, some are compulsory for everyone working at CERN. In particular, “CERN Safety Introduction” and “Safety during LS1” are compulsory for all new arrivals.   The "Self-Rescue Mask" training course. Photo: Christoph Balle. However, depending on the type of activities, the type of workstation, the role you have been assigned (TSO, project leader, etc.) and/or the area where you will be working (e.g. confined spaces), you might be required to follow additional safety training provided by CERN. In accordance with the provisions of the CERN Safety Policy, members of the personnel must keep themselves informed of their obligations in terms of safety training and of the actions they must take to keep up to date. Most training courses are valid for three years, and as they reach the ...

[Suicidal behavior: a psychiatric emergency situation, suicide prevention: a psychiatric obligation].

Science.gov (United States)

Wolfersdorf, M; Schneider, B; Schmidtke, A

2015-09-01

In German psychiatry suicidal behavior is seen as sign of a psychiatric crisis in a person in the context of psychopathology, psychodynamics and psychosocial situation. Psychiatric disorders are found in up to 90% of people who commit suicide and the time span following the decision to commit suicide is often very short, within 24 h. Suicide prevention is a central duty and obligation in psychiatry and psychotherapy. This article gives an overview on the current state of knowledge on suicide from a clinical point of view.

Differential Transcriptional Activation of Genes Encoding Soluble Methane Monooxygenase in a Facultative Versus an Obligate Methanotroph.

Science.gov (United States)

Smirnova, Angela V; Dunfield, Peter F

2018-03-06

Methanotrophs are a specialized group of bacteria that can utilize methane (CH₄) as a sole energy source. A key enzyme responsible for methane oxidation is methane monooxygenase (MMO), of either a soluble, cytoplasmic type (sMMO), or a particulate, membrane-bound type (pMMO). Methylocella silvestris BL2 and Methyloferula stellata AR4 are closely related methanotroph species that oxidize methane via sMMO only. However, Methyloferula stellata is an obligate methanotroph, while Methylocella silvestris is a facultative methanotroph able to grow on several multicarbon substrates in addition to methane. We constructed transcriptional fusions of the mmo promoters of Methyloferula stellata and Methylocella silvestris to a promoterless gfp in order to compare their transcriptional regulation in response to different growth substrates, in the genetic background of both organisms. The following patterns were observed: (1) The mmo promoter of the facultative methanotroph Methylocella silvestris was either transcriptionally downregulated or repressed by any growth substrate other than methane in the genetic background of Methylocella silvetris ; (2) Growth on methane alone upregulated the mmo promoter of Methylocella silvetris in its native background but not in the obligate methanotroph Methyloferula stellata ; (3) The mmo promoter of Methyloferula stellata was constitutive in both organisms regardless of the growth substrate, but with much lower promoter activity than the mmo promoter of Methylocella silvetris . These results support a conclusion that a different mode of transcriptional regulation of sMMO contributes to the facultative lifestyle of Methylocella silvetris compared to the obligate methanotroph Methyloferula stellata .

The legitimacy of raising aquilian claim in the case of destruction of an obligation relation object

Directory of Open Access Journals (Sweden)

Aličić Samir

2011-01-01

Full Text Available If an object which should be submitted on the basis of obligation is unlawfully destroyed, Aquilian claim belongs to the debtor as the owner of the object, regardless of whether it was destroyed by a creditor or a third party, and the debtor is relieved of the obligation. The claim does not belong to him only if the creditor destroys the object while the debtor is delayed, or if a third party destroys the object with the intent to harm the creditor. In the latter case, actio doli belongs to the creditor. Also in cases in which he was denied Aquilian claim, the debtor is freed from liability obligations, if the destroyed object was individually determined. Aquilian claim also belongs to the debtor in case of damage to the object which should be submitted, but if the object is damaged by a third party, the creditor is entitled to require from the debtor Aquilian claim to be left to him. If the detentor destroys or damages the object he that keeps under contract , the creditor can sue him with contract suit or suit for unlawful damage. And if the object is destroyed by a third party, Aquilian claim on the value of the object belongs exclusively to the creditor as the owner of the object, while the detentor can only have the right to Aquilian claim on the value of results of the object, as their owner.

Identification and antimicrobial susceptibility of obligate anaerobic bacteria from clinical samples of animal origin.

Science.gov (United States)

Mayorga, Melissa; Rodríguez-Cavallini, Evelyn; López-Ureña, Diana; Barquero-Calvo, Elías; Quesada-Gómez, Carlos

2015-12-01

The etiology of veterinary infectious diseases has been the focus of considerable research, yet relatively little is known about the causative agents of anaerobic infections. Susceptibility studies have documented the emergence of antimicrobial resistance and indicate distinct differences in resistance patterns related to veterinary hospitals, geographic regions, and antibiotic-prescribing regimens. The aim of the present study was to identify the obligate anaerobic bacteria from veterinary clinical samples and to determinate the in vitro susceptibility to eight antimicrobials and their resistance-associated genes. 81 clinical specimens obtained from food-producing animals, pets and wild animals were examined to determine the relative prevalence of obligate anaerobic bacteria, and the species represented. Bacteroides spp, Prevotella spp and Clostridium spp represented approximately 80% of all anaerobic isolates. Resistance to metronidazole, clindamycin, tetracycline and fluoroquinolones was found in strains isolated from food-producing animals. Ciprofloxacin, enrofloxacin and cephalotin showed the highest resistance in all isolates. In 17%, 4% and 14% of tetracycline-resistant isolates, the resistance genes tetL, tetM and tetW were respectively amplified by PCR whereas in 4% of clindamycin-resistant strains the ermG gene was detected. 26% of the isolates were positive for cepA, while only 6% harbored the cfxA (resistance-conferring genes to beta-lactams). In this study, the obligate anaerobic bacteria from Costa Rica showed a high degree of resistance to most antimicrobials tested. Nevertheless, in the majority of cases this resistance was not related to the resistance acquired genes usually described in anaerobes. It is important to address and regulate the use of antimicrobials in the agricultural industry and the empirical therapy in anaerobic bacterial infections in veterinary medicine, especially since antibiotics and resistant bacteria can persist in the

26 CFR 1.551-3 - Deduction for obligations of the United States and its instrumentalities.

Science.gov (United States)

2010-04-01

... shareholder, his proportionate share of whatever interest on obligations of the United States or its...) Each United States shareholder required to return his distributive share of undistributed foreign... the company for such taxable year, with the exception of any such interest as may be so included by...

49 CFR 17.5 - What is the Secretary's obligation with respect to Federal interagency coordination?

Science.gov (United States)

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false What is the Secretary's obligation with respect to Federal interagency coordination? 17.5 Section 17.5 Transportation Office of the Secretary of Transportation INTERGOVERNMENTAL REVIEW OF DEPARTMENT OF TRANSPORTATION PROGRAMS AND ACTIVITIES § 17.5 What is...

Impacts of renewables obligation with recycling of the buy-out fund

International Nuclear Information System (INIS)

Zhou Huizhong

2012-01-01

Tradable green certificate (TGC) or renewables obligation (RO) programs typically include a buy-out option, but only in the UK the buy-out fund is redistributed back to the suppliers who have submitted the certificates. We show that when the buy-out fund is redistributed, the supply of renewable energy responds positively to the market conditions and renewables target. Without it, the buy-out rate is equivalent to a maximum price. However, redistribution of the buy-out fund may induce strategic behavior from producers who have market power. We analyze the impacts of market power and integration on the supply of conventional and renewable energy under the RO program with the buy-out fund recycled, and devise some empirical tests to predict these impacts. Policy implications of this study are discussed with special reference to the new FiT CfD system. - Highlights: ► The renewables obligation (RO) program in UK redistributes the buy-out fund to those who have submitted ROCs. ► Price of ROCs and hence the renewable energy output increases with the shortfall of renewable energy relative to the RO target. ► Empirical tests suggest that RO in the UK is likely to increase renewables output. ► Integration between conventional and renewables production is unlikely to affect the performance of RO program. ► RO with redistribution is more responsive to market and social preferences than FiT programs.

[Self endangerment to save life--competing Jewish legal and moral obligations].

Science.gov (United States)

Gesundheit, Benjamin; Zlotnick, Eitan; Wygoda, Michael; Rosenzweig, Joshua P; Steinberg, Avraham

2014-11-01

The obligation to help others often involves personal risk. Consequently, the scope and boundaries of this obligation can present a complex dilemma, which has practical and moral implications, even in the world of medicine. In Jewish medical ethics, the dilemma stems from a confrontation between the duty to help others according to the biblical commandment: "Do not stand idly by your fellow's blood" on the one hand, and between the right and duty of man to defend himself, which is anchored in Jewish law. This article surveys the sources of this quandary in Jewish texts throughout the ages such as the Bible, Mishnah, Talmud, and responsa literature in various contexts. The discussion highlights the essential difference between the formal demands of the law, which protects human rights of self-preservation, and the moral requirement to help others even if it may include personal risk. The sources suggest distinguishing between various levels of risk ranging from high-risk to reasonable or low risk. In this way, the classic sources, provide the foundation and the tools for grappling with modern contemporary Halachic questions such as organ transplantation, and generate a Torah value-based framework to deal with new situations that may arise in the future. It is critical to assess the level of risk and the chances for success, along with other subjective considerations, in order to ensure the optimal ethical course of action.

Isolation of obligate anaerobic bacteria from ulcerative keratitis in domestic animals.

Science.gov (United States)

Ledbetter, Eric C; Scarlett, Janet M

2008-01-01

To determine the frequency of obligate anaerobic bacterial isolation from corneal samples of domestic animals with ulcerative keratitis and to characterize the historical, clinical, cytological, and microbiological features of culture-positive cases. Three hundred and thirty domestic animals with ulcerative keratitis. Anaerobic bacteriologic culture and Gram stain were performed on corneal samples from consecutive animals examined with suspect septic ulcerative keratitis. Additional corneal diagnostics included: aerobic bacteriologic culture for all species; fungal culture for ungulates; Mycoplasma culture and virus isolation or feline herpesvirus-1 (FHV-1) polymerase chain reaction (PCR) for cats. Historical, clinical, and cytological findings were correlated with microbiologic data. Anaerobic bacteria were isolated from 13.0% of corneal samples (dogs: 14.0%; horses: 12.9%; cats: 7.9%; alpacas: 18.8%). The most frequent isolates were Clostridium, Peptostreptococcus, Actinomyces, Fusobacterium, and Bacteroides species. The majority of these infections were mixed anaerobic and aerobic bacteria, unless antimicrobial therapy had been administered prior to presentation. The clinical appearance of anaerobic bacterial culture-positive cases was highly variable. Ocular trauma, pre-existing corneal disease, previous corneal surgery, and chronic dermatological disease were significantly (P anaerobic cultures in one or more species. The results of the present study demonstrate that obligate anaerobic bacteria are present within the intralesional flora of ulcerative keratitis in domestic animals. In most species evaluated, these bacteria were identified infrequently. Anaerobic bacterial infection of the cornea most frequently occurs in association with other ocular pathogens and previous corneal abnormalities.

Effects of different temperature regimes on survival of Diaphorina citri and its endosymbiotic bacterial communities.

Science.gov (United States)

Hussain, Mubasher; Akutse, Komivi Senyo; Ravindran, Keppanan; Lin, Yongwen; Bamisile, Bamisope Steve; Qasim, Muhammad; Dash, Chandra Kanta; Wang, Liande

2017-09-01

The Asian citrus psyllid, Diaphorina citri, is a major pest of citrus and vector of citrus greening (huanglongbing) in Asian. In our field-collected psyllid samples, we discovered that Fuzhou (China) and Faisalabad (Pakistan), populations harbored an obligate primary endosymbiont Candidatus Carsonella (gen. nov.) with a single species, Candidatus Carsonella ruddii (sp. nov.) and a secondary endosymbiont, Wolbachia surface proteins (WSP) which are intracellular endosymbionts residing in the bacteriomes. Responses of these symbionts to different temperatures were examined and their host survival assessed. Diagnostic PCR assays showed that the endosymbionts infection rates were not significantly reduced in both D. citri populations after 24 h exposure to cold or heat treatments. Although quantitative PCR assays showed significant reduction of WSP relative densities at 40°C for 24 h, a substantial decrease occurred as the exposure duration increased beyond 3 days. Under the same temperature regimes, Ca. C. ruddii density was initially less affected during the first exposure day, but rapidly reduced at 3-5 days compared to WSP. However, the mortality of the psyllids increased rapidly as exposure time to heat treatment increased. The responses of the two symbionts to unfavorable temperature regimes highlight the complex host-symbionts interactions between D. citri and its associated endosymbionts. © 2017 Society for Applied Microbiology and John Wiley & Sons Ltd.

Considerations on post-production obligations in terms of Atomic Energy Law

International Nuclear Information System (INIS)

Rebentisch, M.

1992-01-01

The article describes and evaluates the laws concerning the decommissioning and dismantling of nuclear power plants and offers suggestions for possible new regulations. The contribution examines fundamental legal aspects, the instrumentalization of post-production obligations in terms of atomic energy laws, especially the question as to how to bring the Atomic Energy Law into accord with the Federal Emission Control Law within the realm of decommissioning laws, licences for safe confinement and dismantling of a plant, and in addition questions on making financial provisions for decommissioning. (orig./HSCH) [de

The transition to non-lead rifle ammunition in Denmark: national obligations and policy considerations

DEFF Research Database (Denmark)

Kanstrup, Niels; Thomas, Vernon G.; Krone, Oliver

2016-01-01

The issue of Denmark regulating use of lead-free rifle ammunition because of potential risks of lead exposure in wildlife and humans was examined from a scientific and objective policy perspective. The consequences of adopting or rejecting such regulation were identified. Denmark is obliged to ex......-contaminated wild game meat. Opposition from hunting organizations would be expected....

Universal Service Obligations: The Role of Subsidization Schemes and the Consequences of Accounting Separation

International Nuclear Information System (INIS)

Mirabel, F.; Poudou, J.C.; Roland, M.

2007-01-01

This paper (i) highlights the role that unit subsidies can play in the compensation scheme of a Universal Service Obligation (USO), and (ii) shows that welfare may be reduced when regulation requires accounting separation of network activities for vertically integrated USO providers. This suggests that accounting separation should be avoided when a USO is implemented. (authors)

Socioeconomic Stress and Academic Adjustment among Asian American Adolescents: The Protective Role of Family Obligation

Science.gov (United States)

Kiang, Lisa; Andrews, Kandace; Stein, Gabriela L.; Supple, Andrew J.; Gonzalez, Laura M.

2013-01-01

Socioeconomic stress has long been found to place youth at risk, with low family income conferring disadvantages in adolescents' school achievement and success. This study investigates the role of socioeconomic stress on academic adjustment, and pinpoints family obligation as a possible buffer of negative associations. We examined direct and…

77 FR 55896 - Notice of Release Effecting Federal Grant Assurance Obligations Due to Airport Layout Plan...

Science.gov (United States)

2012-09-11

... Grant Assurance Obligations Due to Airport Layout Plan Revision at Mather Airport, Sacramento, CA AGENCY... Airport Boulevard, Sacramento, CA 95837. SUPPLEMENTARY INFORMATION: In accordance with the Wendell H. Ford... Mather Airport, Sacramento, California, which will provide for a release from the Grant Agreement...

25 CFR 166.910 - What happens if I do not fulfill my obligation to the BIA?

Science.gov (United States)

2010-04-01

... GRAZING PERMITS Agriculture Education, Education Assistance, Recruitment, and Training § 166.910 What... under agriculture education programs with an obligated service requirement, and who does not accept employment or unreasonably terminates employment must repay us in accordance with the following table: If you...

The Status of Thailand's Implementation of International Treaty Obligations Regarding Linguistic Human Rights in Education

Science.gov (United States)

Draper, John

2013-01-01

Given the recent consideration by the Thai government of a national language policy, this article considers the status of Thailand's treaty obligations regarding linguistic human rights in education. It presents a general background, a brief linguistic profile of Thailand, a concise summary of the concept and importance of linguicide, and a…

12 CFR 1510.5 - How does the Funding Corporation make interest payments on its obligations?

Science.gov (United States)

2010-01-01

... four sources. The Funding Corporation must pay the interest due on its obligations with funds it obtains from the following sources and in the following order: (1) Earnings on assets of the Funding... payment to be paid by the Funding Corporation from sources other than the Secretary and the amounts...

Differential Transcriptional Activation of Genes Encoding Soluble Methane Monooxygenase in a Facultative Versus an Obligate Methanotroph

Directory of Open Access Journals (Sweden)

Angela V. Smirnova

2018-03-01

Full Text Available Methanotrophs are a specialized group of bacteria that can utilize methane (CH4 as a sole energy source. A key enzyme responsible for methane oxidation is methane monooxygenase (MMO, of either a soluble, cytoplasmic type (sMMO, or a particulate, membrane-bound type (pMMO. Methylocella silvestris BL2 and Methyloferula stellata AR4 are closely related methanotroph species that oxidize methane via sMMO only. However, Methyloferula stellata is an obligate methanotroph, while Methylocella silvestris is a facultative methanotroph able to grow on several multicarbon substrates in addition to methane. We constructed transcriptional fusions of the mmo promoters of Methyloferula stellata and Methylocella silvestris to a promoterless gfp in order to compare their transcriptional regulation in response to different growth substrates, in the genetic background of both organisms. The following patterns were observed: (1 The mmo promoter of the facultative methanotroph Methylocella silvestris was either transcriptionally downregulated or repressed by any growth substrate other than methane in the genetic background of Methylocella silvetris; (2 Growth on methane alone upregulated the mmo promoter of Methylocella silvetris in its native background but not in the obligate methanotroph Methyloferula stellata; (3 The mmo promoter of Methyloferula stellata was constitutive in both organisms regardless of the growth substrate, but with much lower promoter activity than the mmo promoter of Methylocella silvetris. These results support a conclusion that a different mode of transcriptional regulation of sMMO contributes to the facultative lifestyle of Methylocella silvetris compared to the obligate methanotroph Methyloferula stellata.

Extending Justice: a rights-based account of our obligations to distant people

OpenAIRE

Fitzgerald, John

2012-01-01

This thesis examines a prima facie tension between the narrow scope of social justice proposed by many liberal, rights-based accounts, and the intuition that we have a strong obligation to help distant people who are in great need. 'Distant people' in this instance are people who do not share our nationality, or those who will come to exist as members of future generations. Ways in which liberal, right-based theories of political philosophy can resolve this tension are examined, and the thesi...

Moving Towards Inclusive Education as a Human Right, An analysis of international legal obligations to implement inclusive education in law and policy

OpenAIRE

Waddington, L.B.; Toepke, C

2014-01-01

Children with disabilities experience ongoing segregation in special education classes or are otherwise excluded from education. This is in spite of the fact that States have a legal obligation to offer an accessible and inclusive education to all learners. Exclusion of any child from education is a violation of international law and a breach of human rights. The provision of inclusive education is an obligation under international law, as well as the means by which to fulfil the additional l...

The International Obligations of the European Union and its Member States with regard to Economic Relations with Israeli Settlements, CNCD, FIDH, 71 p.

OpenAIRE

Dubuisson, François

2014-01-01

The report will demonstrate that under existing international law the EU and its member states have the obligation to refrain from any form of trade or economic relations with Israeli companies established or conducting activities in Palestinian territories. This obligation arises from customary principles that govern States’ international responsibilities and set out the consequences, for third States, of serious breaches of peremptory norms of international law. We will first describe how t...

Reflections on the Maintenance Obligations from the Perspective of the European Law Enforcement

Directory of Open Access Journals (Sweden)

Gabriela LUPŞAN

2014-08-01

Full Text Available As stated, maintaining and developing an area of freedom, security and justice by the European Union, within which it is ensured the free movement of persons, requires the adoption of, among others, the measures relating to judicial cooperation in civil matters which have cross-border implications. These measures are designed to promote the compatibility of the rules applicable in the Member States concerning the conflict of laws and of jurisdiction. Based on the mobility of persons within the European Union, from the desire to protect both debtors of the maintenance, most often children, and the interest to favor a proper administration of justice within the European Union, there were adopted a number of community instruments relating to maintenance, which has provisions on conflicts of jurisdiction, conflict of laws, recognition and enforceability, enforcement of judgments, judicial assistance and cooperation between central authorities. In the first part of the study we analyzed the rules of jurisdiction according to which it is established the jurisdiction of the court hearing a claim for maintenance, when maintenance obligations arise from a family relationship, parentage, marriage or affinity. In the second part of the study, we limited the analysis to the choice of law applicable on in the case of the obligation between parents and their children.

Fulfillment of administrative and professional obligations of hospitals and mission motivation of physicians.

Science.gov (United States)

Trybou, Jeroen; Gemmel, Paul; Desmidt, Sebastian; Annemans, Lieven

2017-01-13

To be successful, hospitals must increasingly collaborate with their medical staff. One strategic tool that plays an important role is the mission statement of hospitals. The goal of this research was to study the relationship between the fulfillment of administrative and professional obligations of hospitals on physicians' motivation to contribute to the mission of the hospital. Furthermore the mediating role of the physicians' emotional attachment to the hospital and moderation effect of the exchange with the head physicians were considered. Self-employed physicians of six hospitals participated in a survey. Descriptive analyses and linear regression were used to analyse the data. The results indicate that affective commitment mediated the relationship between psychological contract fulfillment and mission statement motivation. In addition, the quality of exchange with the Chief Medical Officer moderated the relationship between the fulfillment of administrative obligations and affective commitment positively. This study extends our understanding of social exchange processes and mission statement motivation of physicians. We showed that when physicians perceive a high level of fulfillment of their psychological contract they are more committed and more motivated to contribute to the mission statement. A high quality relationship between physician and Chief Medical Officer can enhance this reciprocity dynamic.

20 CFR 1002.266 - What are the obligations of a multiemployer pension benefit plan under USERRA?

Science.gov (United States)

2010-04-01

... pension benefit plan under USERRA? 1002.266 Section 1002.266 Employees' Benefits OFFICE OF THE ASSISTANT... SERVICES EMPLOYMENT AND REEMPLOYMENT RIGHTS ACT OF 1994 Reemployment Rights and Benefits Pension Plan Benefits § 1002.266 What are the obligations of a multiemployer pension benefit plan under USERRA? A...

An integrated moral obligation model for landowner conservation norms

Science.gov (United States)

Pradhananga, Amit K.; Davenport, Mae A.; Fulton, David C.; Maruyama, Geoffrey M.; Current, Dean

2017-01-01

This study applies an integrated moral obligation model to examine the role of environmental and cultural values, and beliefs in the activation of landowner conservation norms. Data for this study were collected through a self-administered survey of riparian landowners in two Minnesota watersheds: Sand Creek and Vermillion River watersheds. Study findings suggest that collectivistic and biospheric–altruistic values form the bases for the activation of personal norms. Further, beliefs about local responsibility and ability to act influence personal norms to protect water resources. Findings suggest that landowners’ personal norms of water conservation are more likely to be activated by conservation strategies that appeal to biospheric–altruistic and collectivistic values, emphasize adverse consequences of water pollution, highlight water resource protection as a local responsibility, and provide the resources needed to protect water resources.

THE RIGHTS AND OBLIGATIONS OF THE MAIN STAKEHOLDERS IN CLOUD COMPUTING SERVICES

Directory of Open Access Journals (Sweden)

Marioara Maxim

2015-11-01

Full Text Available The current technological progress triggers a new approach in the way the personal data are collected, processed or stored, by a multitude of data controllers or processors involved in the chain of trophic relations in the delivering of cloud computing services. In this circumstances, it is our objective to examine the rights and obligations of the contractual parties involved in the cloud computing agreements according to the European Union law and national legislation, and their legal consequences for the data subjects.

Two-step evolution of endosymbiosis between hydra and algae.

Science.gov (United States)

Ishikawa, Masakazu; Shimizu, Hiroshi; Nozawa, Masafumi; Ikeo, Kazuho; Gojobori, Takashi

2016-10-01

In the Hydra vulgaris group, only 2 of the 25 strains in the collection of the National Institute of Genetics in Japan currently show endosymbiosis with green algae. However, whether the other non-symbiotic strains also have the potential to harbor algae remains unknown. The endosymbiotic potential of non-symbiotic strains that can harbor algae may have been acquired before or during divergence of the strains. With the aim of understanding the evolutionary process of endosymbiosis in the H. vulgaris group, we examined the endosymbiotic potential of non-symbiotic strains of the H. vulgaris group by artificially introducing endosymbiotic algae. We found that 12 of the 23 non-symbiotic strains were able to harbor the algae until reaching the grand-offspring through the asexual reproduction by budding. Moreover, a phylogenetic analysis of mitochondrial genome sequences showed that all the strains with endosymbiotic potential grouped into a single cluster (cluster γ). This cluster contained two strains (J7 and J10) that currently harbor algae; however, these strains were not the closest relatives. These results suggest that evolution of endosymbiosis occurred in two steps; first, endosymbiotic potential was gained once in the ancestor of the cluster γ lineage; second, strains J7 and J10 obtained algae independently after the divergence of the strains. By demonstrating the evolution of the endosymbiotic potential in non-symbiotic H. vulgaris group strains, we have clearly distinguished two evolutionary steps. The step-by-step evolutionary process provides significant insight into the evolution of endosymbiosis in cnidarians. Copyright © 2016 Elsevier Inc. All rights reserved.

Two-Step Evolution of Endosymbiosis between Hydra and Algae

KAUST Repository

Ishikawa, Masakazu

2016-07-09

In the Hydra vulgaris group, only 2 of the 25 strains in the collection of the National Institute of Genetics in Japan currently show endosymbiosis with green algae. However, whether the other non-symbiotic strains also have the potential to harbor algae remains unknown. The endosymbiotic potential of non-symbiotic strains that can harbor algae may have been acquired before or during divergence of the strains. With the aim of understanding the evolutionary process of endosymbiosis in the H. vulgaris group, we examined the endosymbiotic potential of non-symbiotic strains of the H. vulgaris group by artificially introducing endosymbiotic algae. We found that 12 of the 23 non-symbiotic strains were able to harbor the algae until reaching the grand-offspring through the asexual reproduction by budding. Moreover, a phylogenetic analysis of mitochondrial genome sequences showed that all the strains with endosymbiotic potential grouped into a single cluster (cluster γ). This cluster contained two strains (J7 and J10) that currently harbor algae; however, these strains were not the closest relatives. These results suggest that evolution of endosymbiosis occurred in two steps; first, endosymbiotic potential was gained once in the ancestor of the cluster γ lineage; second, strains J7 and J10 obtained algae independently after the divergence of the strains. By demonstrating the evolution of the endosymbiotic potential in non-symbiotic H. vulgaris group strains, we have clearly distinguished two evolutionary steps. The step-by-step evolutionary process provides significant insight into the evolution of endosymbiosis in cnidarians.

Nitrous Oxide Reduction by an Obligate Aerobic Bacterium, Gemmatimonas aurantiaca Strain T-27.

Science.gov (United States)

Park, Doyoung; Kim, Hayeon; Yoon, Sukhwan

2017-06-15

N 2 O-reducing organisms with nitrous oxide reductases (NosZ) are known as the only biological sink of N 2 O in the environment. Among the most abundant nosZ genes found in the environment are nosZ genes affiliated with the understudied Gemmatimonadetes phylum. In this study, a unique regulatory mechanism of N 2 O reduction in Gemmatimonas aurantiaca strain T-27, an isolate affiliated with the Gemmatimonadetes phylum, was examined. Strain T-27 was incubated with N 2 O and/or O 2 as the electron acceptor. Significant N 2 O reduction was observed only when O 2 was initially present. When batch cultures of strain T-27 were amended with O 2 and N 2 O, N 2 O reduction commenced after O 2 was depleted. In a long-term incubation with the addition of N 2 O upon depletion, the N 2 O reduction rate decreased over time and came to an eventual stop. Spiking of the culture with O 2 resulted in the resuscitation of N 2 O reduction activity, supporting the hypothesis that N 2 O reduction by strain T-27 required the transient presence of O 2 The highest level of nosZ transcription (8.97 nosZ transcripts/ recA transcript) was observed immediately after O 2 depletion, and transcription decreased ∼25-fold within 85 h, supporting the observed phenotype. The observed difference between responses of strain T-27 cultures amended with and without N 2 O to O 2 starvation suggested that N 2 O helped sustain the viability of strain T-27 during temporary anoxia, although N 2 O reduction was not coupled to growth. The findings in this study suggest that obligate aerobic microorganisms with nosZ genes may utilize N 2 O as a temporary surrogate for O 2 to survive periodic anoxia. IMPORTANCE Emission of N 2 O, a potent greenhouse gas and ozone depletion agent, from the soil environment is largely determined by microbial sources and sinks. N 2 O reduction by organisms with N 2 O reductases (NosZ) is the only known biological sink of N 2 O at environmentally relevant concentrations (up to ∼1

Joint responsibility between the EU and Member States for non-performance of obligations under multilateral environmental agreements

NARCIS (Netherlands)

Nollkaemper, A.; Morgera, E.

2012-01-01

This chapter explores the basis and manifestations of joint responsibility between the European Union (EU) and its Member States for non-performance of obligations contained in multilateral environmental agreements (MEAs). Joint responsibility has often been advanced as an attractive solution where

Joint Responsibility between the EU and Member States for Non-Performance of Obligations under Multilateral Environmental Agreements

NARCIS (Netherlands)

Nollkaemper, A.

2011-01-01

This chapter explores the basis and manifestations of joint responsibility between the European Union (EU) and its Member States for non-performance of obligations contained in multilateral environmental agreements (MEAs). Joint responsibility has often been advanced as an attractive solution where

48 CFR 719.273-9 - Obligations under the Mentor-Protégé Program.

Science.gov (United States)

2010-10-01

... Mentor-Protégé Program. 719.273-9 Section 719.273-9 Federal Acquisition Regulations System AGENCY FOR... Development (USAID) Mentor-Protégé Program 719.273-9 Obligations under the Mentor-Protégé Program. (a) A Mentor or Protégé may voluntarily withdraw from the Program. However, in no event shall such withdrawal...

14 CFR 382.95 - What are carriers' general obligations with respect to boarding and deplaning assistance?

Science.gov (United States)

2010-01-01

... respect to boarding and deplaning assistance? 382.95 Section 382.95 Aeronautics and Space OFFICE OF THE... BASIS OF DISABILITY IN AIR TRAVEL Boarding, Deplaning, and Connecting Assistance § 382.95 What are carriers' general obligations with respect to boarding and deplaning assistance? (a) As a carrier, you must...

78 FR 37946 - Loan Participations; Purchase, Sale and Pledge of Eligible Obligations; Purchase of Assets and...

Science.gov (United States)

2013-06-25

... purchasing credit union may have years of experience dealing with only one or a few originators. These credit...; Purchase, Sale and Pledge of Eligible Obligations; Purchase of Assets and Assumption of Liabilities AGENCY... reorganize the loan participation rule and focus on the purchase side of loan participation transactions. The...

Unproven stem cell-based interventions & physicians' professional obligations; a qualitative study with medical regulatory authorities in Canada.

Science.gov (United States)

Zarzeczny, Amy; Clark, Marianne

2014-10-14

The pursuit of unproven stem cell-based interventions ("stem cell tourism") is an emerging issue that raises various concerns. Physicians play different roles in this market, many of which engage their legal, ethical and professional obligations. In Canada, physicians are members of a self-regulated profession and their professional regulatory bodies are responsible for regulating the practice of medicine and protecting the public interest. They also provide policy guidance to their members and discipline members for unprofessional conduct. We conducted semi-structured telephone interviews with representatives from six different provincial Colleges of Physicians and Surgeons in Canada to discuss their experiences and perspectives regarding stem cell tourism. Our focus was on exploring how different types of physician involvement in this market would be viewed by physicians' professional regulatory bodies in Canada. When considering physicians' professional obligations, participants drew analogies between stem cell tourism and other areas of medical tourism as well as with some aspects of complementary alternative medicine where existing policies, codes of ethics and regulations provide some guidance. Canadian physicians are required to act in the best interests of their patients, respect patient autonomy, avoid conflicts of interest and pursue evidence-based practice in accordance with accepted standards of care. Physicians who provide unproven treatments falling outside the standard of care, not in the context of an approved research protocol, could be subject to professional discipline. Other types of problematic conduct include referrals involving financial conflict of interest and failure to provide urgent medically necessary care. Areas of ambiguity include physicians' obligations when asked for information and advice about seeking unproven medical treatments, in terms of providing non-urgent follow-up care, and when asked to support efforts to go abroad by

Climate paradox of the G-8: legal obligations, policy declarations and implementation gap

Directory of Open Access Journals (Sweden)

Hans Guenter Brauch

2012-01-01

Full Text Available This article analyzes the climate policy performance of the G-8 from 1992 to 2012 based on their legal commitments (Annex-1 and Annex-B countries under the UNFCCC (1992 and the Kyoto Protocol (1997 and their policy declarations on their GHG reduction goals until 2050. A climate paradox has emerged due to a growing implementation gap in Canada, USA and Japan, while Russia, Germany, UK, France and Italy fulfilled their GHG reduction obligation.

Human Rights, Positive Obligations, and Measures to Prevent Human Trafficking in the UK

OpenAIRE

Turner, Ian David

2015-01-01

Article 4 of the European Convention on Human Rights is freedom from slavery. A key feature of this right is the obligation it imposes on states such as the UK to prevent violations of the freedom, such as the trafficking in human beings, by third parties. This piece finds that the UK’s response to its duties in preventing human trafficking is patchy but concludes that this will be much improved with its new Modern Slavery Bill 2014-15.

Decree no. 2004-251 from March 19, 2004 relative to public utility obligations in the gas sector

International Nuclear Information System (INIS)

2004-03-01

This decree defines the public utility obligations that gas suppliers and gas facility operators (transportation and distribution networks, underground storage facilities, LNG facilities) have to fulfill in order to ensure without interruption the continuity of gas supplies to their clients. (J.S.)

Legal Obligation in the Global Context. Some Remarks on the Boundaries and Allegiances Among Persons Beyond the State

Czech Academy of Sciences Publication Activity Database

Pavlakos, George

-, č. 16 (2012) ISSN 1028-3625 Institutional support: RVO:68378122 Keywords : global legal order * legal obligation * coercion Subject RIV: AG - Legal Sciences http://cadmus.eui.eu/bitstream/handle/1814/21758/RSCAS_2012_16.pdf?sequence=1

Arrest of cytoplasmic streaming induces algal proliferation in green paramecia.

Directory of Open Access Journals (Sweden)

Toshiyuki Takahashi

Full Text Available A green ciliate Paramecium bursaria, bearing several hundreds of endosymbiotic algae, demonstrates rotational microtubule-based cytoplasmic streaming, in which cytoplasmic granules and endosymbiotic algae flow in a constant direction. However, its physiological significance is still unknown. We investigated physiological roles of cytoplasmic streaming in P. bursaria through host cell cycle using video-microscopy. Here, we found that cytoplasmic streaming was arrested in dividing green paramecia and the endosymbiotic algae proliferated only during the arrest of cytoplasmic streaming. Interestingly, arrest of cytoplasmic streaming with pressure or a microtubule drug also induced proliferation of endosymbiotic algae independently of host cell cycle. Thus, cytoplasmic streaming may control the algal proliferation in P. bursaria. Furthermore, confocal microscopic observation revealed that a division septum was formed in the constricted area of a dividing paramecium, producing arrest of cytoplasmic streaming. This is a first report to suggest that cytoplasmic streaming controls proliferation of eukaryotic cells.

10 CFR 2.906 - Obligation of parties to avoid introduction of restricted data or national security information.

Science.gov (United States)

2010-01-01

... data or national security information. 2.906 Section 2.906 Energy NUCLEAR REGULATORY COMMISSION RULES... to Adjudicatory Proceedings Involving Restricted Data and/or National Security Information § 2.906 Obligation of parties to avoid introduction of restricted data or national security information. It is the...

From a Pluralism of Grounds to Proto-Legal Relations: Accounting for the Grounds of Obligations of Justice

Czech Academy of Sciences Publication Activity Database

Pavlakos, George

2017-01-01

Roč. 30, č. 1 (2017), s. 59-74 ISSN 1467-9337 R&D Projects: GA ČR GA15-23955S Institutional support: RVO:68378122 Keywords : responsibility of justice * pluralism * obligation of justice * Mathias Risse Subject RIV: AG - Legal Sciences OBOR OECD: Law

Significant Pre-Accession Factors Predicting Success or Failure During a Marine Corps Officer’s Initial Service Obligation

Science.gov (United States)

2015-12-01

30 grams or less) CO MCD level waiver 317 Prostitution or solicitation for prostitution . 318 Reckless driving, careless, or imprudent (considered...property. 432 Public record; altering, concealing, destroying, mutilating, obligation, or removing. 433 Rape , sexual abuse, sexual assault

Considering mortage as one of the means of securing the execution of obligations recognized in the current Albanian legislation

Directory of Open Access Journals (Sweden)

Neritan Cena

2017-07-01

Full Text Available The mortgage is one of the safest means to guarantee the execution of obligations. The definition of a mortgage is given in the article 560 of the Albanian Civil Code. A mortgage is a defined as concrete right placed on the wealth of a debtor or of a third party, on behalf of the creditor, in order to accomplish an obligation. Nonetheless, despite this initial definition seems to superficially imply that any wealth of the debtor or of a third party can be placed as a mortgage, this is not true because according to the article 561 of the Civil Code, the wealth or properties that can be used as mortgage are the following: Immobile property; Usufructes of these objects (of immobile property apart from the legal usufruct of the parents, as well as other emphiteotic rights over these objects. In any case, the person who places a mortgage on a property must be the owner or when this person is a third party, consent must be given so that a mortgage can be placed on a property to guarantee the accomplishment of obligations on behalf of the debtor. A mortgage can be placed on properties that are already existing at the time of the contract or properties that are about to exist in the future.

A comparative study on the energy policies in Japan and Malaysia in fulfilling their nations' obligations towards the Kyoto Protocol

International Nuclear Information System (INIS)

Lau, Lee Chung; Tan, Kok Tat; Lee, Keat Teong; Mohamed, Abdul Rahman

2009-01-01

Global warming and the associated changes in the world climate pattern have been accepted world wide as the gravest threat to humanity in the 20th century. To mitigate the impacts of global warming, the Kyoto Protocol was established in 1997 with the objective of reducing global greenhouse gases (GHGs) emission, in particular carbon dioxide (CO 2 ), by 5.2% below 1990 levels. Developed nations that ratified the Protocol are committed to GHG reduction targets while developing nations are encouraged to reduce GHG emissions on a voluntary basis. Since most of the GHGs emissions come from the energy sector, energy policy plays an important role in fulfilling the Kyoto Protocol obligations. This year marks the beginning of the commitment period for the 2012 Kyoto Protocol. In this case, it would be worthwhile to compare the energy policies in Malaysia and Japan as these nations move towards fulfilling their obligations towards the Kyoto Protocol; bearing in mind that both countries ratified the Protocol, but that Japan commits a reduction target of 6% while Malaysia bears no obligation. Based on the comparison, recommendations were made on how a developing nation like Malaysia could adopt the policies implemented in Japan to suit local conditions and contribute significantly to GHG reduction.

POSTED WORKERS IN THE TRANSNATIONAL PROVISION OF SERVICES – TREATMENT AND OBLIGATIONS OF EMPLOYERS

Directory of Open Access Journals (Sweden)

Mihaela Catană

2013-11-01

Full Text Available This study aims to clarify some issues concerning the rules applicable to posted workers within the framework of the transnational provision of services and obligations incumbent upon employers, both of those the post and the provision of services to beneficiaries , issues raises a number of practical problems with regard to the distinction in regulating the notion of posting, relative to the internal regulation of the Labour Code (Act 53/2003 - republished on the one hand and the European legislation by the other hand. Thus, the contractual relationships between the employer post their workers to perform work for the benefit of its contractual partner, must be very defined very clearly the relationships between employees and employer posted in Romania and that to which they are posted abroad and the obligations each of them. In preparing this paper were used qualitative and quantitative research methods specific depth research of legal sciences, the sociological method, deductive method on regulations, concepts and theories, comparative method. Expected results of the study consist of a summary of the main regulations, solutions and doctrinal views on the development of an suggestions of law, clarification of the regulations with significance implications for business, citizens in their capacity as workers and also for legal practitioners.

Uso de avisos para la explotación y la trata de jóvenes en América Latina

OpenAIRE

Castillo Murillejo, Norma Constanza; Fundación Universitaria Los Libertadores

2015-01-01

This article presents an interpretative analysis of the resultsof the investigations carried out from the organizations ofcivil society, the State and the academy in Mexico, Argentina,Bolivia, and Colombia, whose object of study has been noticeswith and without sexual content used to attract young peopleto the exploitation and trafficking. It shows answers to basicquestions from the functionalist models, and structuralismcritic of social communication, such as: What is the relationshipbetween...

A method to analyze, sort, and retain viability of obligate anaerobic microorganisms from complex microbial communities.

Science.gov (United States)

Thompson, Anne W; Crow, Matthew J; Wadey, Brian; Arens, Christina; Turkarslan, Serdar; Stolyar, Sergey; Elliott, Nicholas; Petersen, Timothy W; van den Engh, Ger; Stahl, David A; Baliga, Nitin S

2015-10-01

A high speed flow cytometric cell sorter was modified to maintain a controlled anaerobic environment. This technology enabled coupling of the precise high-throughput analytical and cell separation capabilities of flow cytometry to the assessment of cell viability of evolved lineages of obligate anaerobic organisms from cocultures. Copyright © 2015. Published by Elsevier B.V.

Economic-technical effects of electric power quality obligation on the commitments related to the Emeraude contract; Impacts technico-economiques de l`obligation de qualite du courant sur les engagements lies au ``contrat Emeraude``

Energy Technology Data Exchange (ETDEWEB)

Irani, J. [Centre Technique des Industries Mecaniques (CETIM), (France)

1996-12-31

Quality of electric current is guaranteed to its high-voltage clients by the Electricite de France`s Emeraude contract; the main problem is due to the fact that an industrial client does not know the nature of perturbations that its plant generates nor that they may propagate on the EDF distribution system. In that case, these clients will likely be obliged to contribute to EDF`s investments for improving the line quality

'Relief of oppression': an organizing principle for researchers' obligations to participants in observational studies in the developing world.

Science.gov (United States)

Lavery, James V; Bandewar, Sunita V S; Kimani, Joshua; Upshur, Ross E G; Plummer, Frances A; Singer, Peter A

2010-06-30

A central question in the debate about exploitation in international research is whether investigators and sponsors from high-income countries (HIC) have obligations to address background conditions of injustice in the communities in which they conduct their research, beyond the healthcare and other research-related needs of participants, to aspects of their basic life circumstances. In this paper, we describe the Majengo sexually transmitted disease (STD) Cohort study, a long-term prospective, observational cohort of sex workers in Nairobi, Kenya. Despite important scientific contributions and a wide range of benefits to the women of the cohort, most of the women have remained in the sex trade during their long-standing participation in the cohort, prompting allegations of exploitation. The Majengo STD cohort case extends the debate about justice in international research ethics beyond clinical trials into long-term observational research. We sketch the basic features of a new approach to understanding and operationalizing obligations of observational researchers, which we call 'relief of oppression'. 'Relief of oppression' is an organizing principle, analogous to the principle of harm reduction that is now widely applied in public health practice. Relief of oppression aims to help observational researchers working in conditions of injustice and deprivation to clarify their ethical obligations to participants. It aims to bridge the gap between a narrow, transaction-oriented account of avoiding exploitation and a broad account emphasizing obligations of reparation for historic injustices. We propose that relief of oppression might focus researchers' consideration of benefits on those that have some relevance to background conditions of injustice, and so elevate the priority of these benefits, in relation to others that might be considered and negotiated with participants, according to the degree to which the participating communities are constrained in their

Transfer of Rights and Obligations Under DCFR and CESL

DEFF Research Database (Denmark)

Beale, Hugh; Ringe, Georg

The rules on assignment and transfer of rights and obligations are currently outside the scope of the proposed CESL. In contrast, the original DCFR from 2009 includes a chapter on these issues. Questions outside the scope of CESL are left to be solved by the ‘domestic’ provisions of the national....... This concerns above all other areas of law, for example the rules that apply upon the insolvency of one of the parties (in particular that of the assignor) and the rules on public policy. Key differences between the jurisdictions include, inter alia, the proprietary aspects of the assignor’s insolvency where...... the assignor is paid by the debtor, the priority rule for competing assignments, and the effects of a non-assignment clause. Here, the choice of the optional instrument rather than either English or German law will lead to diverging results and may therefore prejudice any of the parties involved....

Preserving children's fertility: two tales about children's right to an open future and the margins of parental obligations.

Science.gov (United States)

Cutas, Daniela; Hens, Kristien

2015-05-01

The sources, extent and margins of parental obligations in taking decisions regarding their children's medical care are subjects of ongoing debates. Balancing children's immediate welfare with keeping their future open is a delicate task. In this paper, we briefly present two examples of situations in which parents may be confronted with the choice of whether to authorise or demand non-therapeutic interventions on their children for the purpose of fertility preservation. The first example is that of children facing cancer treatment, and the second of children with Klinefelter syndrome. We argue that, whereas decisions of whether to preserve fertility may be prima facie within the limits of parental discretion, the right to an open future does not straightforwardly put parents under an obligation to take actions that would detect or relieve future infertility in their children-and indeed in some cases taking such actions is problematic.

THE PRE-CONTRACT OBLIGATIONS REGARDING THE FRANCHISING AGREEMENT

Directory of Open Access Journals (Sweden)

DAN-ALEXANDRU SITARU

2013-05-01

Full Text Available The current paper puts into context the Government Ordinance no. 52/1997 regarding franchising with the new concepts of the Civil Code. Thus, under the old Civil Code there were no specific regulations that could be applied to a pre-contractual obligation of the parties. During any negotiation, because the parties sent each other a series of offers, counter offers, and in the end decided whether to agree or not, some parts of a professional secret, know-how, or any other important information for one or both might be revealed to the other. Under international laws, such as the one in France, or by using internationally established unwritten law, such as the Franchising Model Contract by the International Chamber of Commerce and Arbitration in Paris, such a disclosure of important or secret information is protected from future unauthorized usage by any party or affiliate if the contract is not signed. In the view of the new Civil Code, this stage in the development of an agreement, not yet binding, is now regulated and protected.

Cyber-Dilemmas in the New Millennium: School Obligations to Provide Student Safety in a Virtual School Environment

Science.gov (United States)

Shariff, Shaheen

2005-01-01

Cyber-bullying is a psychologically devastating form of social cruelty among adolescents. This paper reviews the current policy vacuum as it relates to the legal obligations and reasonable expectations of schools to monitor and supervise on-line discourse, while balancing student safety, education, and interaction in virtual space. The paper opens…

Systemwide Report on Value of Supplemental Pension Obligations and Cost of Post-Employment Benefits Other Than Pensions.

Science.gov (United States)

Oklahoma State Regents for Higher Education, Oklahoma City.

This report provides financial data on the value of obligations of any supplemental pension plans and the annual cost of any post-employment benefits for employees of state universities, colleges, and community colleges in Oklahoma. Attachment 1 summarizes information on supplemental pension plans that have been reported by state system…

[Exists an Obligation to be Healthy? Ethical Limits of Medical Prevention].

Science.gov (United States)

Arntz, K

2016-02-01

An obligation to be healthy in the sauce of a categorical imperative "You shall change your life!" (P. Sloterdijk) does not exist. There is however a moral responsibility to shape ones own life in such a way that the resulting potentials for development can be realized within one owns possibilities (I. Kant). The example of predictive medicine illustrates, why the right not to know can be a responsible way of self governance when dealing with the knowledge of modern biomedicine. This allows the setting of limits within prevention, which preserve the quality of life of the exposed as well as enabling the individual the "acceptance of self" (R. Guardini). © Georg Thieme Verlag KG Stuttgart · New York.

Mid and later life care work migration: Patterns of re-organising informal care obligations in Central and Eastern Europe.

Science.gov (United States)

Bauer, Gudrun; Österle, August

2016-04-01

Many women in mid or later life from Central and Eastern Europe commute for live-in 24-hour care work to Austria. In addition to paid care work abroad, the majority of women in this age group is confronted with informal (family) care obligations towards children, towards older relatives or towards grandchildren. This study aims to explore the patterns of re-organising these informal care obligations (childcare, long-term care and domestic work) in the respective home country and to analyse the factors that determine the re-organisation. The study builds on qualitative interviews with 20 migrant care workers aged 40years and over, 9 Romanian and 11 Slovakian women providing 24-hour care work in Austria. All interviewees commute in 2- to 4-weekly shifts between the home country and Austria and report multiple informal care obligations towards family members in the respective home country. In most cases, members of the nuclear and extended family, and in many cases husbands or partners of migrant care workers, act as the main substitute caregivers. Institutional care provision plays a more important role for child care as against for older people in need of care for whom care services are hardly available or accessible in the countries observed. While re-organisation depends much on the specific family constellations, strong assumptions towards family care, the limitations in (monetary) resources and the lack of public welfare provisions strongly co-determine the arrangements. Copyright © 2016 Elsevier Inc. All rights reserved.

Wither Aut Dedere? The Obligation to Extradite or Prosecute after the ICJ's Judgment in Belgium v. Senegal

NARCIS (Netherlands)

Nollkaemper, A.

2013-01-01

In this article I explore a narrow question that was raised, but not fully addressed, in the Questions relating to the Obligation to Prosecute or Extradite (Belgium v Senegal) case: does a state that has custody over a person who is suspected of the crime of torture, but that is unwilling or unable

Wither Aut Dedere? The Obligation to Extradite or Prosecute after the ICJ's Judgment in Belgium v Senegal

NARCIS (Netherlands)

Nollkaemper, A.

2013-01-01

In this article I explore a narrow question that was raised, but not fully addressed, in the Questions relating to the Obligation to Prosecute or Extradite (Belgium v Senegal) case: does a state that has custody over a person who is suspected of the crime of torture, but that is unwilling or unable

The Analysis of the Carrier’s Obligations during the Movement of Goods in Terms of Dual Perspective of the Budapest Convention and the Settlement of the New Civil Code

Directory of Open Access Journals (Sweden)

Ion IORGA

2012-08-01

Full Text Available In the present study we have analyzed one of the most important, but at the same time conflicting, the carrier’s obligations arise under the contract of carriage, that is the compliance of the itinerary while traveling goods to their destination, safely without delay. Using content analysis, through a descriptive documentary research and jurisprudence analysis, this study aims at identifying both the content of the obligation of complying the itinerary established in the contract or the usages that derive from, and particular aspects of this obligation which modifies the original terms of the carriage contract. Also, the paper discusses the texts of the New Civil Code and the Budapest Convention on the carriage contract on inland waterways. To what extent the carrier is entitled to invoke the exemption causes of liability? What are these causes? The paper is in the interest of legal practitioners that confront with the compliance issue of the carrier’s obligations and attracting the liability of the carrier for all damages of the goods, during and after the route deviation from the itinerary in given situation.

77 FR 76356 - Disclosure to Investors in System-wide and Consolidated Bank Debt Obligations of the Farm Credit...

Science.gov (United States)

2012-12-28

... FARM CREDIT ADMINISTRATION 12 CFR Part 630 RIN 3052-AC77 Disclosure to Investors in System-wide and Consolidated Bank Debt Obligations of the Farm Credit System; System Audit Committee; Effective... Corporation System Audit Committee and the Farm Credit System annual report to investors. In accordance with...

Scientists' Ethical Obligations and Social Responsibility for Nanotechnology Research.

Science.gov (United States)

Corley, Elizabeth A; Kim, Youngjae; Scheufele, Dietram A

2016-02-01

Scientists' sense of social responsibility is particularly relevant for emerging technologies. Since a regulatory vacuum can sometimes occur in the early stages of these technologies, individual scientists' social responsibility might be one of the most significant checks on the risks and negative consequences of this scientific research. In this article, we analyze data from a 2011 mail survey of leading U.S. nanoscientists to explore their perceptions the regarding social and ethical responsibilities for their nanotechnology research. Our analyses show that leading U.S. nanoscientists express a moderate level of social responsibility about their research. Yet, they have a strong sense of ethical obligation to protect laboratory workers (in both universities and industry) from unhealthy exposure to nanomaterials. We also find that there are significant differences in scientists' sense of social and ethical responsibility depending on their demographic characteristics, job affiliation, attention to media content, risk perceptions and benefit perceptions. We conclude with some implications for future research.

Thioredoxin system in obligate anaerobe Desulfovibrio desulfuricans: Identification and characterization of a novel thioredoxin 2.

Science.gov (United States)

Sarin, Ritu; Sharma, Yagya D

2006-07-05

Metal corroding sulfate reducing bacteria have been poorly characterized at molecular level due to difficulties pertaining to isolation and handling of anaerobes. We report here for the first time the presence and characterization of thioredoxin 2 in an obligate anaerobic dissimilatory sulfate reducing bacterium Desulfovibrio desulfuricans. In silico analysis of the D. desulfuricans genome revealed the presence of thioredoxin 1 (dstrx1), thioredoxin 2 (dstrx2) and thioredoxin reductase (dstrxR) genes. These genes were found to be actively expressed by the bacteria under the anaerobic growth conditions. We have overexpressed the anaerobic thioredoxin genes in E. coli to produce functionally active recombinant proteins. Recombinant DsTrxR recognized both DsTrx1 and DsTrx2 as its substrate. Mutation studies revealed that the activity of DsTrx2 can be completely abolished with a single amino acid mutation (C69A) in the signature motif 'WCGPC'. Furthermore, the N-terminal domain of DsTrx2 containing two extra CXXC motifs was found to have a negative regulation on its biochemical activity. In conclusion, we have shown the presence of thioredoxin 2 for the first time in an obligate anaerobe which in this anaerobe may be required for its survival under either oxidative stress conditions or metal ion hemostasis.

Dynamic Acquisition and Loss of Dual-Obligate Symbionts in the Plant-Sap-Feeding Adelgidae (Hemiptera: Sternorrhyncha: Aphidoidea)

Science.gov (United States)

Carol D. von Dohlen; Usha Spaulding; Kistie B. Patch; Kathryn M. Weglarz; Robert G. Foottit; Nathan P. Havill; Gaelen R. Burke

2017-01-01

Sap-sucking insects typically engage in obligate relationships with symbiotic bacteria that play nutritional roles in synthesizing nutrients unavailable or in scarce supply from the plant-sap diets of their hosts. Adelgids are sap-sucking insects with complex life cycles that involve alternation between conifer tree species. While all adelgid species feed on spruce...

Family obligation values and family assistance behaviors: protective and risk factors for Mexican-American adolescents' substance use.

Science.gov (United States)

Telzer, Eva H; Gonzales, Nancy; Fuligni, Andrew J

2014-02-01

Adolescent substance use is one of today's most important social concerns, with Latino youth exhibiting the highest overall rates of substance use. Recognizing the particular importance of family connection and support for families from Mexican backgrounds, the current study seeks to examine how family obligation values and family assistance behaviors may be a source of protection or risk for substance use among Mexican-American adolescents. Three hundred and eighty-five adolescents (51% female) from Mexican backgrounds completed a questionnaire and daily diary for 14 consecutive days. Results suggest that family obligation values are protective, relating to lower substance use, due, in part, to the links with less association with deviant peers and increased adolescent disclosure. In contrast, family assistance behaviors are a source of risk within high parent-child conflict homes, relating to higher levels of substance use. These findings suggest that cultural values are protective against substance use, but the translation of these values into behaviors can be a risk factor depending upon the relational context of the family.

Family Obligation Values and Family Assistance Behaviors: Protective and Risk Factors for Mexican-American Adolescents’ Substance Use

Science.gov (United States)

2014-01-01

Adolescent substance use is one of today’s most important social concerns, with Latino youth exhibiting the highest overall rates of substance use. Recognizing the particular importance of family connection and support for families from Mexican backgrounds, the current study seeks to examine how family obligation values and family assistance behaviors may be a source of protection or risk for substance use among Mexican-American adolescents. Three hundred and eighty-five adolescents (51% female) from Mexican backgrounds completed a questionnaire and daily diary for 14 consecutive days. Results suggest that family obligation values are protective, relating to lower substance use, due, in part, to the links with less association with deviant peers and increased adolescent disclosure. In contrast, family assistance behaviors are a source of risk within high parent-child conflict homes, relating to higher levels of substance use. These findings suggest that cultural values are protective against substance use, but the translation of these values into behaviors can be a risk factor depending upon the relational context of the family. PMID:23532598

Serratia symbiotica from the aphid Cinara cedri: a missing link from facultative to obligate insect endosymbiont.

Directory of Open Access Journals (Sweden)

Araceli Lamelas

2011-11-01

Full Text Available The genome sequencing of Buchnera aphidicola BCc from the aphid Cinara cedri, which is the smallest known Buchnera genome, revealed that this bacterium had lost its symbiotic role, as it was not able to synthesize tryptophan and riboflavin. Moreover, the biosynthesis of tryptophan is shared with the endosymbiont Serratia symbiotica SCc, which coexists with B. aphidicola in this aphid. The whole-genome sequencing of S. symbiotica SCc reveals an endosymbiont in a stage of genome reduction that is closer to an obligate endosymbiont, such as B. aphidicola from Acyrthosiphon pisum, than to another S. symbiotica, which is a facultative endosymbiont in this aphid, and presents much less gene decay. The comparison between both S. symbiotica enables us to propose an evolutionary scenario of the transition from facultative to obligate endosymbiont. Metabolic inferences of B. aphidicola BCc and S. symbiotica SCc reveal that most of the functions carried out by B. aphidicola in A. pisum are now either conserved in B. aphidicola BCc or taken over by S. symbiotica. In addition, there are several cases of metabolic complementation giving functional stability to the whole consortium and evolutionary preservation of the actors involved.

Occurrence and molecular characterization of cultivable mesophilic and thermophilic obligate anaerobic bacteria isolated from paper mills.

Science.gov (United States)

Suihko, Maija-Liisa; Partanen, Laila; Mattila-Sandholm, Tiina; Raaska, Laura

2005-08-01

The aim of this work was to characterize the cultivable obligate anaerobic bacterial population in paper mill environments. A total of 177 anaerobically grown bacterial isolates were screened for aerotolerance, from which 67 obligate anaerobes were characterized by automated ribotyping and 41 were further identified by partial 16S rDNA sequencing. The mesophilic isolates indicated 11 different taxa (species) within the genus Clostridium and the thermophilic isolates four taxa within the genus Thermoanaerobacterium and one within Thermoanaerobacter (both formerly Clostridium). The most widespread mesophilic bacterium was closely related to C. magnum and occurred in three of four mills. One mill was contaminated with a novel mesophilic bacterium most closely related to C. thiosulfatireducens. The most common thermophile was T. thermosaccharolyticum, occurring in all four mills. The genetic relationships of the mill isolates to described species indicated that most of them are potential members of new species. On the basis of identical ribotypes clay could be identified to be the contamination source of thermophilic bacteria. Automated ribotyping can be a useful tool for the identification of clostridia as soon as comprehensive identification libraries are available.

Epidemiology of asexuality induced by the endosymbiotic Wolbachia across phytophagous wasp species: host plant specialization matters.

Science.gov (United States)

Boivin, T; Henri, H; Vavre, F; Gidoin, C; Veber, P; Candau, J-N; Magnoux, E; Roques, A; Auger-Rozenberg, M-A

2014-05-01

Among eukaryotes, sexual reproduction is by far the most predominant mode of reproduction. However, some systems maintaining sexuality appear particularly labile and raise intriguing questions on the evolutionary routes to asexuality. Thelytokous parthenogenesis is a form of spontaneous loss of sexuality leading to strong distortion of sex ratio towards females and resulting from mutation, hybridization or infection by bacterial endosymbionts. We investigated whether ecological specialization is a likely mechanism of spread of thelytoky within insect communities. Focusing on the highly specialized genus Megastigmus (Hymenoptera: Torymidae), we first performed a large literature survey to examine the distribution of thelytoky in these wasps across their respective obligate host plant families. Second, we tested for thelytoky caused by endosymbionts by screening in 15 arrhenotokous and 10 thelytokous species for Wolbachia, Cardinium, Arsenophonus and Rickettsia endosymbionts and by performing antibiotic treatments. Finally, we performed phylogenetic reconstructions using multilocus sequence typing (MLST) to examine the evolution of endosymbiont-mediated thelytoky in Megastigmus and its possible connections to host plant specialization. We demonstrate that thelytoky evolved from ancestral arrhenotoky through the horizontal transmission and the fixation of the parthenogenesis-inducing Wolbachia. We find that ecological specialization in Wolbachia's hosts was probably a critical driving force for Wolbachia infection and spread of thelytoky, but also a constraint. Our work further reinforces the hypothesis that community structure of insects is a major driver of the epidemiology of endosymbionts and that competitive interactions among closely related species may facilitate their horizontal transmission. © 2014 John Wiley & Sons Ltd.

Genome-wide analysis of the interaction between the endosymbiotic bacterium Wolbachia and its Drosophila host

Science.gov (United States)

Xi, Zhiyong; Gavotte, Laurent; Xie, Yan; Dobson, Stephen L

2008-01-01

Background Intracellular Wolbachia bacteria are obligate, maternally-inherited, endosymbionts found frequently in insects and other invertebrates. The success of Wolbachia can be attributed in part to an ability to alter host reproduction via mechanisms including cytoplasmic incompatibility (CI), parthenogenesis, feminization and male killing. Despite substantial scientific effort, the molecular mechanisms underlying the Wolbachia/host interaction are unknown. Results Here, an in vitro Wolbachia infection was generated in the Drosophila S2 cell line, and transcription profiles of infected and uninfected cells were compared by microarray. Differentially-expressed patterns related to reproduction, immune response and heat stress response are observed, including multiple genes that have been previously reported to be involved in the Wolbachia/host interaction. Subsequent in vivo characterization of differentially-expressed products in gonads demonstrates that Angiotensin Converting Enzyme (Ance) varies between Wolbachia infected and uninfected flies and that the variation occurs in a sex-specific manner. Consistent with expectations for the conserved CI mechanism, the observed Ance expression pattern is repeatable in different Drosophila species and with different Wolbachia types. To examine Ance involvement in the CI phenotype, compatible and incompatible crosses of Ance mutant flies were conducted. Significant differences are observed in the egg hatch rate resulting from incompatible crosses, providing support for additional experiments examining for an interaction of Ance with the CI mechanism. Conclusion Wolbachia infection is shown to affect the expression of multiple host genes, including Ance. Evidence for potential Ance involvement in the CI mechanism is described, including the prior report of Ance in spermatid differentiation, Wolbachia-induced sex-specific effects on Ance expression and an Ance mutation effect on CI levels. The results support the use of

Genome-wide analysis of the interaction between the endosymbiotic bacterium Wolbachia and its Drosophila host.

Science.gov (United States)

Xi, Zhiyong; Gavotte, Laurent; Xie, Yan; Dobson, Stephen L

2008-01-02

Intracellular Wolbachia bacteria are obligate, maternally-inherited, endosymbionts found frequently in insects and other invertebrates. The success of Wolbachia can be attributed in part to an ability to alter host reproduction via mechanisms including cytoplasmic incompatibility (CI), parthenogenesis, feminization and male killing. Despite substantial scientific effort, the molecular mechanisms underlying the Wolbachia/host interaction are unknown. Here, an in vitro Wolbachia infection was generated in the Drosophila S2 cell line, and transcription profiles of infected and uninfected cells were compared by microarray. Differentially-expressed patterns related to reproduction, immune response and heat stress response are observed, including multiple genes that have been previously reported to be involved in the Wolbachia/host interaction. Subsequent in vivo characterization of differentially-expressed products in gonads demonstrates that Angiotensin Converting Enzyme (Ance) varies between Wolbachia infected and uninfected flies and that the variation occurs in a sex-specific manner. Consistent with expectations for the conserved CI mechanism, the observed Ance expression pattern is repeatable in different Drosophila species and with different Wolbachia types. To examine Ance involvement in the CI phenotype, compatible and incompatible crosses of Ance mutant flies were conducted. Significant differences are observed in the egg hatch rate resulting from incompatible crosses, providing support for additional experiments examining for an interaction of Ance with the CI mechanism. Wolbachia infection is shown to affect the expression of multiple host genes, including Ance. Evidence for potential Ance involvement in the CI mechanism is described, including the prior report of Ance in spermatid differentiation, Wolbachia-induced sex-specific effects on Ance expression and an Ance mutation effect on CI levels. The results support the use of Wolbachia infected cell cultures

A Resistance-Nodulation-Cell Division Family Xenobiotic Efflux Pump in an Obligate Anaerobe, Porphyromonas gingivalis

OpenAIRE

Ikeda, Takeshi; Yoshimura, Fuminobu

2002-01-01

Porphyromonas gingivalis, a gram-negative obligate anaerobe, contains two homologs of an Escherichia coli resistance-nodulation-cell division-type multidrug exporter gene, acrB, in putative operons, together with homologs of membrane fusion protein gene acrA and outer membrane channel gene tolC. MIC determination and accumulation assays with mutants with disruptions of one or more genes showed that one cluster, named xepCAB, pumped out multiple agents including rifampin, puromycin, and ethidi...

Public service obligation in liberalized electricity markets. Who is the provider of last resort?; Jiyuka jidai ni okeru kokyo service gimu. Dare ga last resort kyokyusha to naru k

Energy Technology Data Exchange (ETDEWEB)

Maruyama, M. [Central Research Inst. of Electric Power Industry, Tokyo (Japan)

2000-03-01

Electric power is an asset indispensable to the modern society, and it is needed to secure the universal service. The universal service has been secured by obliging the existing electric utilities operators to supply electric power. However, since the systematical reform in the electric utility business extends down to the liberalization in the retailing sector, it becomes impossible to oblige electric power supply service to supply the same as conventionally. Even under these circumstances, to continuously secure the universal service, a method is considered for obliging special suppliers (last resort suppliers) to supply electric power to users who are unable to be supplied from anyone. This paper studies who should be the last resort supplier using mainly samples from the U.S. (translated by NEDO)

Meteorological and environmental variables affect flight behaviour and decision-making of an obligate soaring bird, the California Condor Gymnogyps californianus

Science.gov (United States)

Poessel, Sharon; Brandt, Joseph; Miller, Tricia A.; Katzner, Todd

2018-01-01

The movements of animals are limited by evolutionary constraints and ecological processes and are strongly influenced by the medium through which they travel. For flying animals, variation in atmospheric conditions is critically influential in movement. Obligate soaring birds depend on external sources of updraft more than do other flying species, as without that updraft they are unable to sustain flight for extended periods. These species are therefore good models for understanding how the environment can influence decisions about movement. We used meteorological and topographic variables to understand the environmental influences on the decision to engage in flight by obligate soaring and critically endangered California Condors Gymnogyps californianus. Condors were more likely to fly, soared at higher altitudes and flew over smoother terrain when weather conditions promoted either thermal or orographic updrafts, for example when turbulence and solar radiation were higher and when winds from the east and north were stronger. However, increased atmospheric stability, which is inconsistent with thermal development but may be associated with orographic updrafts, was correlated with a somewhat higher probability of being in flight at lower altitudes and over rougher terrain. The close and previously undescribed linkages between Condor flight and conditions that support development of thermal and orographic updrafts provide important insight into the behaviour of obligate soaring birds and into the environmental parameters that may define the currently expanding distribution of Condors within and outside the state of California.

Anaerobic oxidation of fatty acids by Clostridium bryantii sp. nov. : a sporeforming, obligately syntrophic bacterium

OpenAIRE

Stieb, Marion; Schink, Bernhard

1985-01-01

From marine and freshwater mud samples strictly anaerobic, Gram-positive, sporeforming bacteria were isolated which oxidized fatty acids in obligately syntrophic association with H2-utilizing bacteria. Even-numbered fatty acids with up to 10 carbon atoms were degraded to acetate and Hz, odd-numbered fatty acids with up to 11 carbon atoms including 2-methylbutyrate were degraded to acetate, propionate and H2. Neither fumarate, sulfate, thiosulfate, sulfur, nor nitrate were reduced. A marine is...

Tsetse immune system maturation requires the presence of obligate symbionts in larvae.

Directory of Open Access Journals (Sweden)

Brian L Weiss

2011-05-01

Full Text Available Beneficial microbial symbionts serve important functions within their hosts, including dietary supplementation and maintenance of immune system homeostasis. Little is known about the mechanisms that enable these bacteria to induce specific host phenotypes during development and into adulthood. Here we used the tsetse fly, Glossina morsitans, and its obligate mutualist, Wigglesworthia glossinidia, to investigate the co-evolutionary adaptations that influence the development of host physiological processes. Wigglesworthia is maternally transmitted to tsetse's intrauterine larvae through milk gland secretions. We can produce flies that lack Wigglesworthia (Gmm(Wgm- yet retain their other symbiotic microbes. Such offspring give rise to adults that exhibit a largely normal phenotype, with the exception being that they are reproductively sterile. Our results indicate that when reared under normal environmental conditions Gmm(Wgm- adults are also immuno-compromised and highly susceptible to hemocoelic E. coli infections while age-matched wild-type individuals are refractory. Adults that lack Wigglesworthia during larval development exhibit exceptionally compromised cellular and humoral immune responses following microbial challenge, including reduced expression of genes that encode antimicrobial peptides (cecropin and attacin, hemocyte-mediated processes (thioester-containing proteins 2 and 4 and prophenoloxidase, and signal-mediating molecules (inducible nitric oxide synthase. Furthermore, Gmm(Wgm- adults harbor a reduced population of sessile and circulating hemocytes, a phenomenon that likely results from a significant decrease in larval expression of serpent and lozenge, both of which are associated with the process of early hemocyte differentiation. Our results demonstrate that Wigglesworthia must be present during the development of immature progeny in order for the immune system to function properly in adult tsetse. This phenomenon provides

Genome of Methylobacillus flagellatus, Molecular Basis for Obligate Methylotrophy, and Polyphyletic Origin of Methylotrophy

Energy Technology Data Exchange (ETDEWEB)

Chistoserdova, L; Lapidus, A; Han, C; Godwin, L; Saunders, L; Brettin, T; Tapia, R; Gilna, P; Lucas, S; Richardson, P M; Lidstrom, M E

2007-07-24

Along with methane, methanol and methylated amines represent important biogenic atmospheric constituents; thus, not only methanotrophs but also nonmethanotrophic methylotrophs play a significant role in global carbon cycling. The complete genome of a model obligate methanol and methylamine utilizer, Methylobacillus flagellatus (strain KT) was sequenced. The genome is represented by a single circular chromosome of approximately 3 Mbp, potentially encoding a total of 2,766 proteins. Based on genome analysis as well as the results from previous genetic and mutational analyses, methylotrophy is enabled by methanol and methylamine dehydrogenases and their specific electron transport chain components, the tetrahydromethanopterin-linked formaldehyde oxidation pathway and the assimilatory and dissimilatory ribulose monophosphate cycles, and by a formate dehydrogenase. Some of the methylotrophy genes are present in more than one (identical or nonidentical) copy. The obligate dependence on single-carbon compounds appears to be due to the incomplete tricarboxylic acid cycle, as no genes potentially encoding alpha-ketoglutarate, malate, or succinate dehydrogenases are identifiable. The genome of M. flagellatus was compared in terms of methylotrophy functions to the previously sequenced genomes of three methylotrophs, Methylobacterium extorquens (an alphaproteobacterium, 7 Mbp), Methylibium petroleiphilum (a betaproteobacterium, 4 Mbp), and Methylococcus capsulatus (a gammaproteobacterium, 3.3 Mbp). Strikingly, metabolically and/or phylogenetically, the methylotrophy functions in M. flagellatus were more similar to those in M. capsulatus and M. extorquens than to the ones in the more closely related M. petroleiphilum species, providing the first genomic evidence for the polyphyletic origin of methylotrophy in Betaproteobacteria.

Human Rights Discourse in the Sustainable Development Agenda Avoids Obligations and Entitlements

Science.gov (United States)

Williams, Carmel; Blaiklock, Alison

2016-01-01

Our commentary on Forman et al paper explores their thesis that right to health language can frame global health policy responses. We examined human rights discourse in the outcome documents from three 2015 United Nations (UN) summits and found rights-related terms are used in all three. However, a deeper examination of the discourse finds the documents do not convey the obligations and entitlements of human rights and international human rights law. The documents contain little that can be used to empower the participation of those already left behind and to hold States and the private sector to account for their human rights duties. This is especially worrying in a neoliberal era. PMID:27285518

Funding for universal service obligations in electricity sector: the case of green power development

International Nuclear Information System (INIS)

Favard, P.; Mirabel, F.; Poudou, J.Ch.

2002-07-01

The process of deregulation in network industries, in particular in the electric sector, raises the problem of financing the Universal Service Obligations (USO) corresponding to the production, transport and distribution operations. In this paper, we study three ways of funding for an USO of production, especially the 'green' electricity development; the financing with cross-subsidies, the implementation of a fund (financing by a tax) and finally a voluntary funding system by direct subscriptions of consumers. We notably show that this last one Pareto dominates mostly, from a welfare point of view, the other scenarios. (authors)

THE EFFECTS OF DIVIDEND POLICY AND OWNERSHIP STRUCTURE TOWARDS DEBT POLICY

Directory of Open Access Journals (Sweden)

Marcella Fransisca Santosa

2014-07-01

Full Text Available This research used multiple regression methods to examine the relationshipbetween the dividend policy, institutional ownership, and insider ownership withthe debt policy. Hypotheses tests of this researchused 64 manufacturingcompanies which were listed in the Indonesian StockExchange (IDX from theyear of 2007 until 2010 as the samples. The resultsof this research show that thedividend policies and the insider ownership had noeffects towards the debtpolicy, while the institutional ownership had a significant negative effect towardsthe debt policy.

Perspectives of Students on Acceptance of Tablets and Self-directed Learning with Technology

OpenAIRE

Gokcearslan, Sahin

2017-01-01

Recent mobile learning technologies offer the opportunity for students to take charge ofthe learning process both inside and outside the classroom. One of these tools is the tabletPC (hereafter ‘tablet’). In parallel with increased access to e-content, the role of tablets inlearning has recently begun to be examined. This study aims to reveal the relationshipbetween the level of acceptance of tablets (TAM) and the level of selfdirectedlearning with technology (SDLT) of students and to differe...

Proton Therapy: Ever Shifting Sands and the Opportunities and Obligations Within

Directory of Open Access Journals (Sweden)

Christine E Hill-Kayser

2011-09-01

Full Text Available Proton therapy is associated with significant benefit in terms of normal tissue sparing and potential radiation dose escalation for many patients with malignant diseases. Due to recognition of these qualities, the availability of this technology is increasing rapidly. Such expansion is associated with increased opportunity to provide this beneficial technology to larger numbers of patients; however, the importance of careful treatment planning and delivery, deliberate patient selection, rigorous scientific investigation, and mindfulness of ethical issues and cost-effectiveness must not be forgotten. The obligation to move forward responsibly rests on the shoulders of radiation oncologists around the world. In this article, we discuss current use of proton therapy worldwide, as well as many of the factors that must be taken into account during rapid expansion of this exciting technology.

Cause of contract: French influence on the Law on Obligations of the Republic of Serbia

Directory of Open Access Journals (Sweden)

Dudaš Atila

2011-01-01

Full Text Available In this paper the author analyzes the influence of the French Civil Code on the effective Serbian Law on Obligations from 1978 in respect of the cause of contract. This is an institution in respect of which the Law conspicuously departs from the Swiss Law on Obligations, which served as its prime legislative model, and follows the path designated in the French code. The author concludes that the Serbian law transcripts almost verbatim the rules of law in the French code pertaining to the cause of contract. However, its provisions are somewhat more detailed than those of the French counterpart, since it explicitly governs the impact of motives on the validity of a contract as well. Analyzing the Serbian case-law, the author concludes that motives gain legal relevance in Serbian contract law in two different ways. On the one hand, courts confirm the proposition adopted in the doctrine that in gratuitous contracts (permitted motives pertain to the notion of cause. On the other hand, illicit, non-permitted motives make gratuitous contracts void regardless whether the other party acted in good faith or not, while they render onerous contracts void only if the other party acted in bad faith, that is, he or she knew or should have known that the first party was guided by illicit motives to conclude the contract.

Clarifying the role of fire heat and daily temperature fluctuations as germination cues for Mediterranean Basin obligate seeders.

Science.gov (United States)

Santana, Victor M; Baeza, M Jaime; Blanes, M Carmen

2013-01-01

This study aims to determine the role that both direct effects of fire and subsequent daily temperature fluctuations play in the seed bank dynamics of obligate seeders from the Mediterranean Basin. The short yet high soil temperatures experienced due to passage of fire are conflated with the lower, but longer, temperatures experienced by daily fluctuations which occur after removing vegetation. These germination cues are able to break seed dormancy, but it is difficult to assess their specific level of influence because they occur consecutively after summer fires, just before the flush of germination in the wet season (autumn). By applying experimental fires, seed treatments were imposed that combined fire exposure/non-fire exposure with exposure to microhabitats under a gradient of disturbance (i.e. gaps opened by fire, mechanical brushing and intact vegetation). The seeds used were representative of the main families of obligate seeders (Ulex parviflorus, Cistus albidus and Rosmarinus officinalis). Specifically, an assessment was made of (1) the proportion of seeds killed by fire, (2) seedling emergence under field conditions and (3) seeds which remained ungerminated in soil. For the three species studied, the factors that most influenced seedling emergence and seeds remaining ungerminated were microhabitats with higher temperature fluctuations after fire (gaps opened by fire and brushing treatments). The direct effect of fire decreased the seedling emergence of U. parviflorus and reduced the proportion of seeds of R. officinalis remaining ungerminated. The relevance of depleting vegetation (and subsequent daily temperature fluctuation in summer) suggests that studies focusing on lower temperature thresholds for breaking seed dormancy are required. This fact also supports the hypothesis that the seeding capacity in Mediterranean Basin obligate seeders may have evolved as a response to a wide range of disturbances, and not exclusively to fire.

STUDY OF THE ANTIMICROBIAL PROPERTIES OF CERTAIN SAPROPHYTIC OBLIGATE MARINE FUNGI

Directory of Open Access Journals (Sweden)

Kalyuzhnaya O.S.

2015-05-01

Full Text Available Today promising area of the development and introduction of new antimicrobial agents is to search for new antibiotics from natural sources, namely among marine organisms - microscopic fungi. Such saprophytic fungi as Ascomycota (families Arenariomyces, Ceriosporopsis, Corollospora, Halosphaeria and Basidiomycota (family Nia, which are widely spreaded in Ukraine (salty estuaries and the coast of the Black Sea, are the objects of the study of this work. These types of marine organisms have been provided by the Odessa Branch of the Institute of Biology of the Southern Seas after collecting samples of water, sediment, cellulose substrates and subsequent isolation and obtain pure cultures by accumulation in the form fruiting bodies of Ascomycetes and Basidiomycetes - ascocarps and basidiocarps that can be stored 3-5 months in sterile seawater. The aim of this study was to investigate the presence of antimicrobial properties of saprophytic fungi obligate marine, which are characteristic for residents in Ukraine, namely the Black Sea. Materials and methods. At this stage the study of antimicrobial activity was performed by agar diffusion method and method of cocultivation of marine fungi with test strains in liquid culture medium. We have used reference strains of microorganisms: Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 25923, Bacillus subtilis ATCC 6633, Proteus vulgaris ATCC 6896, Pseudomonas aeruginosa ATCC 27853 and opportunistic fungus Candida albicans ATCC 885-653. Results and Discussion. Determination of antimicrobial activity by agar diffusion method showed that all samples had antimicrobial activity against the Gram-positive test strains (S. aureus and B. subtilis, effect for the Gramnegative bacteria (E. coli, P. vulgaris, P. aeruginosa was much smaller or non-existent, and it isn’t observed against C. albicans (exclusion Nia vibrissa with zone of growth inhibition – 6.2 mm. The results of the counting of cells test strains

31 CFR 357.13 - Obligations of the United States and the Federal Reserve Banks with respect to Book-entry...

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Obligations of the United States and... 357.13 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL... BONDS, NOTES AND BILLS HELD IN LEGACY TREASURY DIRECT Treasury/Reserve Automated Debt Entry System...

Subcellular trace element distribution in Geosiphon pyriforme

International Nuclear Information System (INIS)

Maetz, Mischa; Schuessler, Arthur; Wallianos, Alexandros; Traxel, Kurt

1999-01-01

Geosiphon pyriforme is a unique endosymbiotic consortium consisting of a soil dwelling fungus and the cyanobacterium Nostoc punctiforme. At present this symbiosis becomes very interesting because of its phylogenetic relationship to the arbuscular mycorrhizal (AM) fungi. Geosiphon pyriforme could be an important model system for these obligate symbiotic fungi, which supply 80-90% of all land plant species with nutrients, in particular phosphorous and trace elements. Combined PIXE and STIM analyses of the various compartments of Geosiphon give hints for the matter exchange between the symbiotic partners and their environment and the kind of nutrient storage and acquisition, in particular related to nitrogen fixation and metabolism. To determine the quality of our PIXE results we analysed several geological and biological standards over a time period of three years. This led to an overall precision of about 6% and an accuracy of 5-10% for nearly all detectable elements. In combination with the correction model for the occurring mass loss during the analyses this holds true even for biological targets

Subcellular trace element distribution in Geosiphon pyriforme

Energy Technology Data Exchange (ETDEWEB)

Maetz, Mischa E-mail: mischa.maetz@mpi-hd.mpg.de; Schuessler, Arthur; Wallianos, Alexandros; Traxel, Kurt

1999-04-02

Geosiphon pyriforme is a unique endosymbiotic consortium consisting of a soil dwelling fungus and the cyanobacterium Nostoc punctiforme. At present this symbiosis becomes very interesting because of its phylogenetic relationship to the arbuscular mycorrhizal (AM) fungi. Geosiphon pyriforme could be an important model system for these obligate symbiotic fungi, which supply 80-90% of all land plant species with nutrients, in particular phosphorous and trace elements. Combined PIXE and STIM analyses of the various compartments of Geosiphon give hints for the matter exchange between the symbiotic partners and their environment and the kind of nutrient storage and acquisition, in particular related to nitrogen fixation and metabolism. To determine the quality of our PIXE results we analysed several geological and biological standards over a time period of three years. This led to an overall precision of about 6% and an accuracy of 5-10% for nearly all detectable elements. In combination with the correction model for the occurring mass loss during the analyses this holds true even for biological targets.

Outsourcing ethical obligations: should the revised common rule address the responsibilities of investigators and sponsors?

Science.gov (United States)

Shah, Seema K

2013-01-01

The Common Rule creates a division of moral labor in research. It implies that investigators and sponsors can outsource their ethical obligations to IRBs and participants, thereby fostering a culture of compliance, rather than one of responsibility. The proposed revisions to the Common Rule are likely to exacerbate this problem. To harness the expressive power of the law, I propose the Common Rule be revised to include the ethical responsibilities of investigators and sponsors. © 2013 American Society of Law, Medicine & Ethics, Inc.

12 CFR 987.2 - Law governing rights and obligations of Banks, Finance Board, Office of Finance, United States...

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Law governing rights and obligations of Banks, Finance Board, Office of Finance, United States and Federal Reserve Banks; rights of any Person against Banks, Finance Board, Office of Finance, United States and Federal Reserve Banks. 987.2 Section 987.2 Banks and Banking FEDERAL HOUSING FINANCE...

17 CFR 270.27d-1 - Reserve requirements for principal underwriters and depositors to carry out the obligations to...

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Reserve requirements for....27d-1 Reserve requirements for principal underwriters and depositors to carry out the obligations to... reserve and as security for the purpose of assuring the refund of charges required by sections 27(d) and...

Convention on Nuclear Safety. Second national report on the implementation by france of the obligations of the Convention; Convention sur la surete nucleaire. Deuxieme rapport national sur la mise en oeuvre par la France des obligations de la Convention

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-09-15

The first national report on the implementation by france of the obligation under the Convention is structured along its Articles. the french Nuclear safety Authority ensured the co ordination of the report, with contributions from other regulators and nuclear operators. this report was distributed at the middle of April 2003 to the other Contracting party (on 3 november to 14, 2003 at the IAEA headquarters. (author)

Antimicrobial resistance and prevalence of resistance genes of obligate anaerobes isolated from periodontal abscesses.

Science.gov (United States)

Xie, Yi; Chen, Jiazhen; He, Junlin; Miao, Xinyu; Xu, Meng; Wu, Xingwen; Xu, Beiyun; Yu, Liying; Zhang, Wenhong

2014-02-01

This study attempts to determine the antimicrobial resistance profiles of obligate anaerobic bacteria that were isolated from a periodontal abscess and to evaluate the prevalence of resistance genes in these bacteria. Forty-one periodontal abscess samples were cultivated on selective and non-selective culture media to isolate the oral anaerobes. Their antibiotic susceptibilities to clindamycin, doxycycline, amoxicillin, imipenem, cefradine, cefixime, roxithromycin, and metronidazole were determined using the agar dilution method, and polymerase chain reaction assays were performed to detect the presence of the ermF, tetQ, nim, and cfxA drug resistance genes. A total of 60 different bacterial colonies was isolated and identified. All of the isolates were sensitive to imipenem. Of the strains, 6.7%, 13.3%, 16.7%, and 25% were resistant to doxycycline, metronidazole, cefixime, and amoxicillin, respectively. The resistance rate for both clindamycin and roxithromycin was 31.7%. Approximately 60.7% of the strains had the ermF gene, and 53.3% of the amoxicillin-resistant strains were found to have the cfxA gene. Two nim genes that were found in eight metronidazole-resistant strains were identified as nimB. In the present study, the Prevotella species are the most frequently isolated obligate anaerobes from periodontal abscesses. The current results show their alarmingly high resistance rate against clindamycin and roxithromycin; thus, the use of these antibiotics is unacceptable for the empirical therapy of periodontal abscesses. A brief prevalence of four resistance genes in the anaerobic bacteria that were isolated was also demonstrated.

Qualité et obligations de résultats

CERN Document Server

Guthapfel, C

1998-01-01

Un contrat de maintenance peut appartenir à deux grands types ; ceux où la prestation est définie par son contenu ou par son résultat. Dans l'exemple retenu, le résultat est exprimé principalement en terme d'état de référence à maintenir ; ce qui nécessite de définir préalablement l'état requis par rapport aux besoins exprimés ou implicites et l'écart toléré d'où une meilleure définition du besoin. Cette approche qualité responsabilise de manière plus complète le contractant par une facilité accrue de mesurer la conformité au besoin et la preuve de manquements aux obligations contractuelles est plus aisée à établir. Il faut toutefois noter un décalage entre les besoins exprimés et ressentis et la difficulté d'apprécier objectivement les résultats, d'où la nécessité d'améliorer et de formaliser les relations client/fournisseur. C'est uniquement sur ces bases que le partenariat, condition indispensable de l'efficience, peut se développer et les besoins être satisfaits au m...

Funding for universal service obligations in electricity sector: the case of green power development

Energy Technology Data Exchange (ETDEWEB)

Favard, P.; Mirabel, F.; Poudou, J.Ch

2002-07-01

The process of deregulation in network industries, in particular in the electric sector, raises the problem of financing the Universal Service Obligations (USO) corresponding to the production, transport and distribution operations. In this paper, we study three ways of funding for an USO of production, especially the 'green' electricity development; the financing with cross-subsidies, the implementation of a fund (financing by a tax) and finally a voluntary funding system by direct subscriptions of consumers. We notably show that this last one Pareto dominates mostly, from a welfare point of view, the other scenarios. (authors)

Differential Transcriptional Activation of Genes Encoding Soluble Methane Monooxygenase in a Facultative Versus an Obligate Methanotroph

OpenAIRE

Angela V. Smirnova; Peter F. Dunfield

2018-01-01

Methanotrophs are a specialized group of bacteria that can utilize methane (CH4) as a sole energy source. A key enzyme responsible for methane oxidation is methane monooxygenase (MMO), of either a soluble, cytoplasmic type (sMMO), or a particulate, membrane-bound type (pMMO). Methylocella silvestris BL2 and Methyloferula stellata AR4 are closely related methanotroph species that oxidize methane via sMMO only. However, Methyloferula stellata is an obligate methanotroph, while Methylocella silv...

Sapwood Area Related to Tree Size, Tree Age, and Leaf Area Index in Cedrus libani

OpenAIRE

Güney, Aylin

2018-01-01

Sapwoodincludes the water conducting part of the stem which transports water andminerals from roots to leaves. Studies using sap flow gauges have to determinethe area of the sapwood in order to scale measured sap flow densities to thetree or stand level. The aim of this study was to investigate the relationshipbetween sapwood area at breast height and other tree parameters which are easyto measure of the montane Mediterranean conifer Cedrus libani, including a total number of 92 study trees o...

Changing International ‘Subjectivity’ and Rights and Obligations under International Law – Status of Corporations

Directory of Open Access Journals (Sweden)

Merja Pentikäinen

2012-01-01

Full Text Available Globalisation, liberation of trade supported by institutions such as the WTO, the unprecedented internationalisation of companies' activities in the global market, the creation of even larger company entities (including multinational corporations and the ensuing growth of business power have radically restructured the equilibrium of companies' relations with state and society. In the contemporary world many companies are de facto stronger and more influential actors than states, and their activities have concrete effects on political, cultural and societal aspects in the countries where they operate or to which they have other business links. These developments have created new kinds of challenges, e.g. for the protection of human rights which may be undermined by business activities. In this situation corporations are increasingly expected to pay due regard to avoiding activities contributing to human rights violations. The doctrine of subjects of international law (international 'subjectivity' considers states as the primary subjects, in addition to which also some other actors have been granted the status as a subject, including even corporations. This article sheds light on the shifts that have taken place in the doctrine of international 'subjectivity' and the paradigm of rights and obligations under international law linked to this 'subjectivity'. Particular attention is paid to the position of corporations, and the exploration is conducted through the prism of the development of rights and obligations in the area of international human rights law.

Treatment of Neuroblastoma with an Engineered "Obligate" Anaerobic Salmonella typhimurium Strain YB1.

Science.gov (United States)

Ning, Bo-Tao; Yu, Bin; Chan, Shing; Chan, Jian-Liang; Huang, Jian-Dong; Chan, Godfrey Chi-Fung

2017-01-01

Purpose Neuroblastoma is an embryonic solid tumor derived from the progenitors of the sympathetic nervous system. More than half of the patients developed metastatic disease at the time of initial diagnosis and had poor outcome with current therapeutic approaches. In recent years, some obligate and facultative anaerobic bacteria were reported to target the hypoxic and necrotic region of solid tumor models and caused tumor regression. We recently successfully constructed an "obligate" anaerobic Salmonella strain YB1 that was applied in breast cancer nude mice model by us. Here, we report the application of YB1 in neuroblastoma treatment. Methods The anti-cancer effect and side-effects of YB1 was examined in both in vitro and in vivo experiment. Previous established orthotopic neuroblastoma SCID/beige murine model using SK-NLP/luciferase cell line was adopted. Results In vitro , YB1 induced apoptosis for up to 31.4% of the neuroblastoma cells under anaerobic condition, three times more than that under aerobic condition (10.9%). The expression of both Toll like Receptor 4 and 5 (TLR4 and TLR5) in cancer cells were significantly up-regulated ( p anaerobic condition. In mouse model, YB1 preferentially accumulated inside the core of the tumors, rather than in normal tissues as our previous reported. This is suggestive of the hypoxic nature of tumor core. Tumor growth was significantly retarded in YB1 treatment group ( n=6, P<0.01 ). Furthermore, there was no long-term organ damage noted in all the organs examined including heart, lung, liver, spleen and brain in the YB1 treated mice. Conclusion The genetic modified Salmonella strain YB1 is a promising anti-tumor strategy against the tumor bulk for neuroblastoma. Future study can be extended to other common cancer types to verify the relative efficacy on different neoplastic cells.

Physicians' obligations to patients infected with Ebola: echoes of acquired immune deficiency syndrome.

Science.gov (United States)

Minkoff, Howard; Ecker, Jeffrey

2015-04-01

Physicians across the United States are engaged in training in the identification, isolation, and initial care of patients with Ebola. Some will be asked to do more. The issue this viewpoint will address is the moral obligation of physicians to participate in these activities. In order to do so the implicit contract between society and its physicians will be considered, as will many of the arguments that are redolent of those that were litigated 30 years ago when acquired immune deficiency syndrome (AIDS) was raising public fears to similar levels, and some physicians were publically proclaiming their unwillingness to render care to those individuals. We will build the case that if steps are taken to reduce risks-optimal personal protective equipment and training-to what is essentially the lowest possible level then rendering care should be seen as obligatory. If not, as in the AIDS era there will be an unfair distribution of risk, with those who take their obligations seriously having to go beyond their fair measure of exposure. It would also potentially undermine patients' faith in the altruism of physicians and thereby degrade the esteem in which our profession is held and the trust that underpins the therapeutic relationship. Finally there is an implicit contract with society. Society gives tremendously to us; we encumber a debt from all society does and offers, a debt for which recompense is rarely sought. The mosaic of moral, historical, and professional imperatives to render care to the infected all echoes the words of medicine's moral leaders in the AIDS epidemic. Arnold Relman perhaps put it most succinctly, "the risk of contracting the patient's disease is one of the risks that is inherent in the profession of medicine. Physicians who are not willing to accept that risk…ought not be in the practice of medicine." Copyright © 2015 Elsevier Inc. All rights reserved.

Diversity of extracellular proteins during the transition from the ‘proto-apicomplexan’ alveolates to the apicomplexan obligate parasites

KAUST Repository

Templeton, Thomas J.; Pain, Arnab

2015-01-01

The recent completion of high-coverage draft genome sequences for several alveolate protozoans – namely, the chromerids, Chromera velia and Vitrella brassicaformis ; the perkinsid Perkinsus marinus ; the apicomplexan, Gregarina niphandrodes , as well as high coverage transcriptome sequence information for several colpodellids, allows for new genome-scale comparisons across a rich landscape of apicomplexans and other alveolates. Genome annotations can now be used to help interpret fine ultrastructure and cell biology, and guide new studies to describe a variety of alveolate life strategies, such as symbiosis or free living, predation, and obligate intracellular parasitism, as well to provide foundations to dissect the evolutionary transitions between these niches. This review focuses on the attempt to identify extracellular proteins which might mediate the physical interface of cell–cell interactions within the above life strategies, aided by annotation of the repertoires of predicted surface and secreted proteins encoded within alveolate genomes. In particular, we discuss what descriptions of the predicted extracellular proteomes reveal regarding a hypothetical last common ancestor of a pre-apicomplexan alveolate – guided by ultrastructure, life strategies and phylogenetic relationships – in an attempt to understand the evolution of obligate parasitism in apicomplexans.

Diversity of extracellular proteins during the transition from the ‘proto-apicomplexan’ alveolates to the apicomplexan obligate parasites

KAUST Repository

Templeton, Thomas J.

2015-11-20

The recent completion of high-coverage draft genome sequences for several alveolate protozoans – namely, the chromerids, Chromera velia and Vitrella brassicaformis ; the perkinsid Perkinsus marinus ; the apicomplexan, Gregarina niphandrodes , as well as high coverage transcriptome sequence information for several colpodellids, allows for new genome-scale comparisons across a rich landscape of apicomplexans and other alveolates. Genome annotations can now be used to help interpret fine ultrastructure and cell biology, and guide new studies to describe a variety of alveolate life strategies, such as symbiosis or free living, predation, and obligate intracellular parasitism, as well to provide foundations to dissect the evolutionary transitions between these niches. This review focuses on the attempt to identify extracellular proteins which might mediate the physical interface of cell–cell interactions within the above life strategies, aided by annotation of the repertoires of predicted surface and secreted proteins encoded within alveolate genomes. In particular, we discuss what descriptions of the predicted extracellular proteomes reveal regarding a hypothetical last common ancestor of a pre-apicomplexan alveolate – guided by ultrastructure, life strategies and phylogenetic relationships – in an attempt to understand the evolution of obligate parasitism in apicomplexans.

Phenotypic and genotypic Characterization of facultative and obligate Alkalophilic Bacillus sp. isolated from Saudi Arabia alkaline soils

Directory of Open Access Journals (Sweden)

Assaeedi Abdulrahman

2014-10-01

Full Text Available Isolation and identification of new alkalophilic Bacillus strains have been increasing interest due to their possessing valuable and commercially interesting enzymes. In the present study, a total six obligate and facultative alkalophilic isolates were isolated from desert soil around the Al-qunfotha city, Saudi Arabia. All isolates were phenotypically and genotypically characterized. Among these isolates; AS3, AS4, AS5 and AS6 could grow at pH 9, 10, 11 and 12, but could not grow at pH 7, indicates that these isolates are obligate alkalophiles. While, isolates AS1 and AS2 grew at pH ranged from 7 to 10, but could not grow at pH 11 and 12, suggesting that they could be facultative alkalophiles. All isolates could hydrolyze casein and starch, indicating that they possess interesting amylase and protease enzymes. Based on 16S rDNA data, the phylogenetic analysis of these strains showed that all six alkalophilic Bacillus belonged to Bacillus cohnii with 99% similarity. The nucleotide sequences of 16S rRNA gene for the six isolates were deposited in a Gene-bank under accession numbers; KP053301, KP053302, KP053303, KP053304, KP053305 and KP053306, respectively.

Genome-wide functional divergence after the symbiosis of proteobacteria with insects unraveled through a novel computational approach.

Directory of Open Access Journals (Sweden)

Christina Toft

2009-04-01

Full Text Available Symbiosis has been among the most important evolutionary steps to generate biological complexity. The establishment of symbiosis required an intimate metabolic link between biological systems with different complexity levels. The strict endo-cellular symbiotic bacteria of insects are beautiful examples of the metabolic coupling between organisms belonging to different kingdoms, a eukaryote and a prokaryote. The host (eukaryote provides the endosymbiont (prokaryote with a stable cellular environment while the endosymbiont supplements the host's diet with essential metabolites. For such communication to take place, endosymbionts' genomes have suffered dramatic modifications and reconfigurations of proteins' functions. Two of the main modifications, loss of genes redundant for endosymbiotic bacteria or the host and bacterial genome streamlining, have been extensively studied. However, no studies have accounted for possible functional shifts in the endosymbiotic proteomes. Here, we develop a simple method to screen genomes for evidence of functional divergence between two species clusters, and we apply it to identify functional shifts in the endosymbiotic proteomes. Despite the strong effects of genetic drift in the endosymbiotic systems, we unexpectedly identified genes to be under stronger selective constraints in endosymbionts of aphids and ants than in their free-living bacterial relatives. These genes are directly involved in supplementing the host's diet with essential metabolites. A test of functional divergence supports a strong relationship between the endosymbiosis and the functional shifts of proteins involved in the metabolic communication with the insect host. The correlation between functional divergence in the endosymbiotic bacterium and the ecological requirements of the host uncovers their intimate biochemical and metabolic communication and provides insights on the role of symbiosis in generating species diversity.

Convention on Nuclear Safety. Second national report on the implementation by france of the obligations of the Convention

International Nuclear Information System (INIS)

2001-09-01

The first national report on the implementation by france of the obligation under the Convention is structured along its Articles. the french Nuclear safety Authority ensured the co ordination of the report, with contributions from other regulators and nuclear operators. this report was distributed at the middle of April 2003 to the other Contracting party (on 3 november to 14, 2003 at the IAEA headquarters. (author)

Image analyzing method to evaluate in situ bioluminescence from an obligate anaerobe cultivated under various dissolved oxygen concentrations.

Science.gov (United States)

Ninomiya, Kazuaki; Yamada, Ryuji; Matsumoto, Masami; Fukiya, Satoru; Katayama, Takane; Ogino, Chiaki; Shimizu, Nobuaki

2013-02-01

An image analyzing method was developed to evaluate in situ bioluminescence expression, without exposing the culture sample to the ambient oxygen atmosphere. Using this method, we investigated the effect of dissolved oxygen concentration on bioluminescence from an obligate anaerobe Bifidobacterium longum expressing bacterial luciferase which catalyzes an oxygen-requiring bioluminescent reaction. Copyright © 2012 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

Obligations and characteristics applicable to the French unit of the 1400 MWe series. Adaptation to the 900 and 1300 MWe series

International Nuclear Information System (INIS)

Conte, M.

1985-10-01

This report presents the directives concerning the obligations and the main characteristics of the nuclear PWR units of 1400 MWe, notified Electricite de France on the 06th of October 1983 by the Industry and Research Department. They reflect the concept of defence in depth [fr

Theories of cause (consideration of contract in the Serbian doctrine of civil law after the adoption of the Law on Obligations

Directory of Open Access Journals (Sweden)

Dudaš Atila

2012-01-01

Full Text Available The adoption of the Law on Obligations in 1978 can certainly be considered as an event of watershed importance in respect to the analysis of various theoretical points of view on the notion of cause (consideration of contract in the Serbian literature. The fact that it had not been explicitly regulated in Serbian positive law until the adoption of Law had a profound impact on the evolution of doctrine in this period. The range of differing theoretical points of view was very wide, covering essentially all the relevant streams in the doctrine of cause, from the ones accepting it (so-called causalistic theories, through the ones explaining it solely by the notion of exchange of assets (so-called economic theories, to the ones denying its legal significance in any sense (so called anticausalistic theories. The most distinguished authorities in Serbian literature of contract law, who studied the notion of cause of contract in the period until the promulgation of the Law, were Dragoljub Aranđelović, Živojin Perić, Lazar Marković, Andrija Gams, Stevan Jakšić, Vladimir Kapor and Mihailo Konstantinović. The Law on Obligations explicitly regulates the notion of cause of contract as one of the preconditions of validity and effect of a contract, which had a substantial impact on the evolution of doctrine. On the one hand, being an institution of positive law, there is hardly an author who had not devoted some attention to the notion of cause of contract. In this paper the author analyzes the points of view of Stojan Cigoj, Ljubiša Milošević, Živomir Đorđević, Boris Vizner, Martin Vedriš, Želimir Šmalcelj, Jakov Radišić, Slobodan Perović, Jožef Salma and Oliver Antić. On the other hand, the scope of various, often conflicting, theories on cause of contract in Serbian literature shrank. One can recognize a tendency of abandonment of points of view disavowing any legal relevance of cause of contract and the majority of contemporary

31 CFR 354.2 - Law governing rights and obligations of Federal Reserve Banks, and Sallie Mae; rights of any...

Science.gov (United States)

2010-07-01

... on the books of a Federal Reserve Bank pursuant to § 354.4(c)(1), is governed by the law (not... recorded on the books of a Federal Reserve Bank pursuant to § 354.14(c)(1), is governed by the law... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Law governing rights and obligations...

Learning from experience? The development of the Renewables Obligation in England and Wales 2002-2010

International Nuclear Information System (INIS)

Woodman, B.; Mitchell, C.

2011-01-01

The UK has enviable renewable resources, both onshore (wind) and offshore (wind, wave and tidal) (). The government has had policy mechanisms in place since 1990 to encourage these resources to be developed. The current mechanism, the Renewables Obligation (RO), was specifically designed to emphasise competition and therefore to fit in with the UK's overall strategic approach to energy policy. However, as yet, it has not delivered the capacity that it was designed to do, and as a result the UK faces a difficult challenge in attempting to meet European-wide renewable energy targets for 2020, as well as longer term decarbonisation targets. This paper explores some of the major reasons why the RO has performed so poorly to date and considers the prospects for improvement up to 2020. It concludes that the strategic emphasis on competition in the support mechanisms has played a key role in limiting renewables development, but that the mechanism has changed significantly since it was introduced. However, these changes, together with proposals for electricity market reform, still do not address important elements of risk in comparison with a standard Feed In Tariff. - Highlights: → We outline the design of the Renewables Obligation and some shortcomings. → The mechanism has performed poorly because of the risks it entails for investors. → It has been subject to several changes which increasingly challenge the original design of the RO. → Future developments may introduce even more fundamental change for supporting renewable. → Over time risks have been reduced but not yet eliminated.

Expression of arsenic resistance genes in the obligate anaerobe Bacteroides vulgatus ATCC 8482, a gut microbiome bacterium

OpenAIRE

Li, Jiaojiao; Mandal, Goutam; Rosen, Barry P.

2016-01-01

The response of the obligate anaerobe Bacteroides vulgatus ATCC 8482, a common human gut microbiota, to arsenic was determined. B. vulgatus ATCC 8482 is highly resistant to pentavalent As(V) and methylarsenate (MAs(V)). It is somewhat more sensitive to trivalent inorganic As(III) but 100-fold more sensitive to methylarsenite (MAs(III)) than to As(III). B. vulgatus ATCC 8482 has eight continuous genes in its genome that we demonstrate form an arsenical-inducible transcriptional unit. The first...

THE GENERAL RULE ON CHOICE OF LAW FOR NON-CONTRACTUAL OBLIGATIONS IN LEGISLATION OF EUROPEAN UNION AND BOSNIA AND HERZEGOVINA

Directory of Open Access Journals (Sweden)

Jasmina Alihodžić

2014-01-01

Full Text Available The project of unification of private international law on the level of European Union encompassed bringing of unique choice of law rules, among others, in the area of non-contractual obligations with international element. A communitarian legislator chose a set of flexible choice of law rules that enable satisfaction of the principle of legal certainty together with the establishment of a balance between persons claiming to be liable and sustaining damage. PIL Act that is being enforced in Bosnia and Herzegovina in relation to the subject of this paper alternatively determines the law applicable to non-contractual obligations, according to the law of the place where the harmful act was done or the law of where the consequence occurred, depending on which of these two laws is more favorable to the person sustaining damage. The author of this paper points out the evident discrepancy in the general rules of determination in EU legislation and Bosnia and Herzegovina, and the need to harmonize legislation in this field with the acquis communautaire, arising from the Stabilization and Association Agreement.

THE GENERAL RULE ON CHOICE OF LAW FOR NON-CONTRACTUAL OBLIGATIONS IN LEGISLATION OF EUROPEAN UNION AND BOSNIA AND HERZEGOVINA

Directory of Open Access Journals (Sweden)

Jasmina Alihodžić

2014-01-01

Full Text Available The project of unification of private international law on the level of European Union encompassed bringing of unique choice of law rules, among others, in the area of non-contractual obligations with international element. A communitarian legislator chose a set of flexible choice of law rules that enable satisfaction of the principle of legal certainty together with the establishment of a balance between persons claiming to be liable and sustaining damage. PIL Act that is being enforced in Bosnia and Herzegovina in relation to the subject of this paper alternatively determines the law applicable to non-contractual obligations, according to the law of the place where the harmful act was done or the law of where the consequence occurred, depending on which of these two laws is more favorable to the person sustaining damage. The author of this paper points out the evident discrepancy in the general rules of determination in EU legislation and Bosnia and Herzegovina, and the need to harmonize legislation in this field with the acquis communautaire, arising from the Stabilization and Association Agreement

Endosymbiotic microorganisms of scale insects

Directory of Open Access Journals (Sweden)

Mónica Rosenblueth

2018-01-01

Full Text Available Parte del éxito evolutivo y ecológico de los insectos se atribuye a las bacterias y hongos asociados a ellos queamplían sus capacidades metabólicas o les permiten resistir estrés o parasitosis. Las asociaciones posiblemente seoriginaron hace cientos de millones de años y el resultado es una interdependencia que, en algunos casos, insectoy bacteria no pueden existir separadamente, lo que ha llevado a una reducción significativa de los genomas de lossimbiontes bacterianos y a la transferencia por vía materna de éstos a la progenie. Recientemente, el estudio delos simbiontes de insectos ha cobrado gran interés y se han identificado algunas de sus funciones biológicas dentrode los hospederos. Los insectos escama o cochinillas se alimentan de la savia de las plantas, por lo que requierensimbiontes para compensar las deficiencias de su dieta, rica en carbono pero pobre en compuestos nitrogenados.Algunas de las plagas más agresivas de los cultivos agrícolas son los insectos escama. En este artículo revisamos lossimbiontes de la cochinilla del carmín y de la laca, de gran interés comercial y artesanal. En las cochinillas que seestudiaron encontramos diversas comunidades microbianas con la capacidad de sintetizar aminoácidos, vitaminas,fijar nitrógeno o reciclar los productos de desecho del metabolismo nitrogenado.

Endosymbiotic microorganisms of scale insects

OpenAIRE

Mónica Rosenblueth; Julio Martínez-Romero; Shamayim Tabita Ramírez-Puebla; Arturo Vera-Ponce de León; Tania Rosas-Pérez; Rafael Bustamante-Brito; Reiner Rincón-Rosales; Esperanza Martínez-Romero

2018-01-01

Parte del éxito evolutivo y ecológico de los insectos se atribuye a las bacterias y hongos asociados a ellos queamplían sus capacidades metabólicas o les permiten resistir estrés o parasitosis. Las asociaciones posiblemente seoriginaron hace cientos de millones de años y el resultado es una interdependencia que, en algunos casos, insectoy bacteria no pueden existir separadamente, lo que ha llevado a una reducción significativa de los genomas de lossimbiontes bacterianos y a la transferencia p...

How dentists account for social responsibility: economic imperatives and professional obligations.

Science.gov (United States)

Dharamsi, Shafik; Pratt, Daniel D; MacEntee, Michael I

2007-12-01

This study explores how dentists explain the concept of social responsibility and its relationship to issues affecting access to oral health care by vulnerable segments of the population. Analysis of open-ended interviews with thirty-four dentists, including dental educators, and administrators and officials of dental public health programs in Canada and the United States revealed that four main themes-economics, professionalism, individual choice, and politics-influenced the respondents' sense of social responsibility in dentistry. There was a belief that social responsibility in dentistry is dominated by economic imperatives that impact negatively on the policies and practices directing access to care. Yet, despite the highly critical stance on dentistry as a business, there was practical recognition of the economic realities of dental practice. Nevertheless, those who focused on social responsibility as a professional obligation highlighted the privileges of self-governance along with the accompanying duty to serve the welfare of everyone and not just those who are socioeconomically advantaged.

Proton Therapy: Ever Shifting Sands and the Opportunities and Obligations within

Energy Technology Data Exchange (ETDEWEB)

Hill-Kayser, Christine E.; Both, Stefan; Tochner, Zelig, E-mail: hill@uphs.upenn.edu [Department of Radiation Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (United States)

2011-09-06

Proton therapy is associated with significant benefit in terms of normal tissue sparing and potential radiation dose escalation for many patients with malignant diseases. Due to recognition of these qualities, the availability of this technology is increasing rapidly, both through increased availability of large centers, and with the possibility of smaller, lower cost proton therapy centers. Such expansion is associated with increased opportunity to provide this beneficial technology to larger numbers of patients; however, the importance of careful treatment planning and delivery, deliberate patient selection, rigorous scientific investigation including comparison to other technologies when possible, and mindfulness of ethical issues and cost effectiveness must not be forgotten. The obligation to move forward responsibly rests on the shoulders of radiation oncologists around the world. In this article, we discuss current use of proton therapy worldwide, as well as many of the factors that must be taken into account during rapid expansion of this exciting technology.

Two New Software Behavioral Design Patterns: Obligation Link and History Reminder

Directory of Open Access Journals (Sweden)

Stefan Andrei

2016-06-01

Full Text Available Finding proper design patterns has always been an important research topic in the software engineering community. One of the main responsibilities of the software developers is to determine which design pattern fits best to solve a particular problem. Design patterns support the effort of exploring the use of artificial intelligence in better management of software development and maintenance process by providing faster, less costly, smarter and on-time decisions (Pena-Mora & Vadhavkar, 1996. There has been a permanent interest in finding new design patterns, especially in the last two decades. Many new design patterns apply in various areas of computer science, such as software security, software parallelism, large-scale software evolving, artificial intelligence, and more. To the best of our knowledge, the “Obligation Link” and “History Reminder” design patterns are new and can be applied in software development in many areas of computer science including artificial intelligence.

Frequency of resistance in obligate anaerobic bacteria isolated from dogs, cats, and horses to antimicrobial agents.

Science.gov (United States)

Lawhon, S D; Taylor, A; Fajt, V R

2013-11-01

Clinical specimens from dogs, cats, and horses were examined for the presence of obligate anaerobic bacteria. Of 4,018 specimens cultured, 368 yielded 606 isolates of obligate anaerobic bacteria (248 from dogs, 50 from cats, and 308 from horses). There were 100 specimens from 94 animals from which only anaerobes were isolated (25 dogs, 8 cats, and 61 horses). The most common sites tested were abdominal fluid (dogs and cats) and intestinal contents (horses). The most common microorganism isolated from dogs, cats, and horses was Clostridium perfringens (75, 13, and101 isolates, respectively). The MICs of amoxicillin with clavulanate, ampicillin, chloramphenicol, metronidazole, and penicillin were determined using a gradient endpoint method for anaerobes. Isolates collected at necropsy were not tested for antimicrobial susceptibility unless so requested by the clinician. There were 1/145 isolates tested that were resistant to amoxicillin-clavulanate (resistance breakpoint ≥ 16/8 μg/ml), 7/77 isolates tested were resistant to ampicillin (resistance breakpoint ≥ 2 μg/ml), 4/242 isolates tested were resistant to chloramphenicol (resistance breakpoint ≥ 32 μg/ml), 12/158 isolates tested were resistant to clindamycin (resistance breakpoint ≥ 8 μg/ml), 10/247 isolates tested were resistant to metronidazole (resistance breakpoint ≥ 32 μg/ml), and 54/243 isolates tested were resistant to penicillin (resistance breakpoint ≥ 2 μg/ml). These data suggest that anaerobes are generally susceptible to antimicrobial drugs in vitro.

Consequences of the quota requirement for energy efficiency. Can a Swedish quota obligation systems give less energy usage?; Konsekvenser av kvotplikt foer energieffektivisering. Kan ett svenskt kvotpliktssystem ge mindre energianvaendning?

Energy Technology Data Exchange (ETDEWEB)

Bjoerkroth, Sara; Bladh, Mats; Holmberg, Rurik; Lock, Anna; Naderi, Ronak; Widerstroem, Glenn

2012-11-01

The Agency has on behalf of the government investigated what the consequences would be of the introduction of a compulsory quota system in Sweden. Under the proposed new EU directive on energy efficiency, all Member States should introduce a compulsory quota system, where energy companies actively initiate measures for energy efficiency among end users. In Sweden, a quota obligation system of this kind would mean energy efficiency of about 3 TWh per year, which can be difficult to achieve. The Swedish Energy Agency suggests that if a compulsory quota system is introduced, the quota obligation should be placed on the network companies. If not, there is a risk of complications in the Swedish and Nordic electricity market. The Energy Markets Inspectorate consider that the quota obligation can not be on the network companies because of their function as regulated monopoly. The Swedish Energy Agency suggests that efficiency measures can be implemented in all sectors, including transport.

Moving Towards Inclusive Education as a Human Right, An analysis of international legal obligations to implement inclusive education in law and policy

NARCIS (Netherlands)

Waddington, L.B.; Toepke, C

2014-01-01

Children with disabilities experience ongoing segregation in special education classes or are otherwise excluded from education. This is in spite of the fact that States have a legal obligation to offer an accessible and inclusive education to all learners. Exclusion of any child from education is a

26 CFR 1.1232-3A - Inclusion as interest of original issue discount on certain obligations issued after May 27, 1969.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Inclusion as interest of original issue discount... Special Rules for Determining Capital Gains and Losses § 1.1232-3A Inclusion as interest of original issue discount on certain obligations issued after May 27, 1969. (a) Ratable inclusion as interest—(1) General...

Investigation On Ethics In Public Sector Necessity Or Obligation Planning A Conceptual Model

Directory of Open Access Journals (Sweden)

N. Ghozat

2015-06-01

Full Text Available Abstract These All the objectives are attainable in line with ethics and if a system is not ethical in spite of scientific and modern facilities it cannot achieve its goals so the main duty of managers is to provide ground for morality since trustworthy morality are the fundamental axes in any system this article has tried to consider ethical issues according Islamic and Iranian values how should be the view point toward ethics in any system is it a necessity or obligation In this article we are to provide a conceptual model base on Iranian situation so our article which is a descriptive one uses multi sources of gathering data questionnaire interview to criticize the theoretical views based on western values and to offer a conceptual model.

Analysis of convergent gene transcripts in the obligate intracellular bacterium Rickettsia prowazekii.

Directory of Open Access Journals (Sweden)

Andrew Woodard

2011-01-01

Full Text Available Termination of transcription is an important component of bacterial gene expression. However, little is known concerning this process in the obligate intracellular pathogen and model for reductive evolution, Rickettsia prowazekii. To assess transcriptional termination in this bacterium, transcripts of convergent gene pairs, some containing predicted intrinsic terminators, were analyzed. These analyses revealed that, rather than terminating at a specific site within the intervening region between the convergent genes, most of the transcripts demonstrated either a lack of termination within this region, which generated antisense RNA, or a putative non-site-specific termination that occurred throughout the intervening sequence. Transcripts terminating at predicted intrinsic terminators, as well as at a putative Rho-dependant terminator, were also examined and found to vary based on the rickettsial host environment. These results suggest that transcriptional termination, or lack thereof, plays a role in rickettsial gene regulation.

Savannah River Site's H-Canyon Facility: Impacts of Foreign Obligations on Special Nuclear Material Disposition

International Nuclear Information System (INIS)

Magoulas, Virginia

2013-01-01

The US has a non-proliferation policy to receive foreign and domestic research reactor returns of spent fuel materials of US origin. These spent fuel materials are returned to the Department of Energy (DOE) and placed in storage in the L-area spent fuel basin at the Savannah River Site (SRS). The foreign research reactor returns fall subject to the 123 agreements for peaceful cooperation. These ''123 agreements'' are named after section 123 of the Atomic Energy Act of 1954 and govern the conditions of nuclear cooperation with foreign partners. The SRS management of these foreign obligations while planning material disposition paths can be a challenge.

Genetic Transformation of an Obligate Anaerobe, P. gingivalis for FMN-Green Fluorescent Protein Expression in Studying Host-Microbe Interaction

OpenAIRE

Choi, Chul Hee; DeGuzman, Jefferson V.; Lamont, Richard J.; Yilmaz, Özlem

2011-01-01

The recent introduction of "oxygen-independent" flavin mononucleotide (FMN)-based fluorescent proteins (FbFPs) is of major interest to both eukaryotic and prokaryotic microbial biologists. Accordingly, we demonstrate for the first time that an obligate anaerobe, the successful opportunistic pathogen of the oral cavity, Porphyromonas gingivalis, can be genetically engineered for expression of the non-toxic green FbFP. The resulting transformants are functional for studying dynamic bacterial pr...

Obligation for the reporting of events and internal organization structure for information of the authorities by the utility

International Nuclear Information System (INIS)

Mueller, H.J.; Scheer, J.

1997-01-01

The obligation of the utilities for the reporting of events to the authorities responsible for nuclear regulation and safety of the public is shown in this report. As an example the nuclear power plants of PreussenElektra Brokdorf and Stade are taken. The internal organization structure and the ways of communication to the authorities are discribed. Furthermore, the outlook and structure of the report which is used for alarm and information of the authorities is shown. (orig.) [de

Swiss legislation on radioactive waste management. Obligations under the state treaty; national legal regulations; roles of the players

International Nuclear Information System (INIS)

Buehlmann, W.

2008-01-01

On December 23, 1959, the Swiss Parliament adopted the ''Federal Act on Atomic Energy and Radiation Protection.'' The Nuclear Power Act of March 21, 2003 constitutes a comprehensive legal regime on radioactive waste. The article outlines the obligations incurred by Switzerland under the state treaty in the ''Joint Agreement on the Safety of Management of Spent Fuel Elements and the Safety of Radioactive Waste Management'' as well as their practical implementation. For the management of radioactive waste, the Nuclear Power Act envisages the concept of underground geologic storage to be transferred into a repository after a phase of observation. The underground geologic store requires a framework permit to be issued by the Federal Council and approved by Parliament. In Switzerland, framework permits are subject to facultative referenda, i.e., there is the possibility of a plebiscite. Article 5 of the Nuclear Power Ordinance regulates the competences in the procedure to build a repository: ''The Federation, in a substantive plan, lays down the objectives and criteria for storing radioactive waste in underground geologic stores in a way binding on the authorities.'' The structure and the duties and obligations of the players involved as set out in the ''Underground Geologic Storage'' plan establish a credible basis of the ongoing site selection procedure and further steps to be taken in building an underground store in Switzerland. (orig.)

The role and obligations of non-executive directors under Maltese law

Directory of Open Access Journals (Sweden)

Emma Grech

2014-01-01

Full Text Available The corporate governance debate has, in the last two decades, reached a stronghold in Europe. Perhaps the most valuable aspect of a company’s governance is the constitution of its boardroom. Nonexecutive directors, in their independent and impartial, supposedly external nature, serve to keep the company’s managerial section in check. Indeed, their function is primarily supervisory, working to ensure that the company’s interests are looked to by the company’s executive guise. Unfortunately, Maltese law does not regulate the post of the non-executive director in a hard and fast manner. Instead, the authorities have chosen to recognise this entity through the inclusion of his role in various non-binding guidelines and soft law mechanisms. The question that shall be tackled in this paper is whether it is acceptable, in this day and age, for the non-executive director is post which deserves a proper defining of its role and obligations within hard law. A brief comparison to foreign jurisdictions has been included for the sake of completeness.

Energy-mediated versus ammonium-regulated gene expression in the obligate ammonia-oxidizing bacterium, Nitrosococcus oceani

Directory of Open Access Journals (Sweden)

Lisa Y Stein

2013-09-01

Full Text Available Ammonia serves as the source of energy and reductant and as a signaling molecule that regulates gene expression in obligate ammonia-oxidizing chemolithotrophic microorganisms. The gammaproteobacterium, Nitrosococcus oceani, was the first obligate ammonia-oxidizer isolated from seawater and is one of the model systems for ammonia chemolithotrophy. We compared global transcriptional responses to ammonium and the catabolic intermediate, hydroxylamine, in ammonium-starved and non-starved cultures of N. oceani to discriminate transcriptional effects of ammonium from a change in overall energy and redox status upon catabolite availability. The most highly expressed genes from ammonium- or hydroxylamine-treated relative to starved cells are implicated in catabolic electron flow, carbon fixation, nitrogen assimilation, ribosome structure and stress tolerance. Catabolic inventory-encoding genes, including electron flow-terminating Complexes IV, FoF1 ATPase, transporters, and transcriptional regulators were among the most highly expressed genes in cells exposed only to ammonium relative to starved cells, although the differences compared to steady-state transcript levels were less pronounced. Reduction in steady-state mRNA levels from hydroxylamine-treated relative to starved-cells were less than five-fold. In contrast, several transcripts from ammonium-treated relative to starved cells were significantly less abundant including those for forward Complex I and a gene cluster of cytochrome c encoding proteins. Identified uneven steady-state transcript levels of co-expressed clustered genes support previously reported differential regulation at the levels of transcription and transcript stability. Our results differentiated between rapid regulation of core genes upon a change in cellular redox status versus those responsive to ammonium as a signaling molecule in N. oceani, both confirming and extending our knowledge of metabolic modules involved in ammonia

Evolution of small prokaryotic genomes

Directory of Open Access Journals (Sweden)

David José Martínez-Cano

2015-01-01

Full Text Available As revealed by genome sequencing, the biology of prokaryotes with reduced genomes is strikingly diverse. These include free-living prokaryotes with ~800 genes as well as endosymbiotic bacteria with as few as ~140 genes. Comparative genomics is revealing the evolutionary mechanisms that led to these small genomes. In the case of free-living prokaryotes, natural selection directly favored genome reduction, while in the case of endosymbiotic prokaryotes neutral processes played a more prominent role. However, new experimental data suggest that selective processes may be at operation as well for endosymbiotic prokaryotes at least during the first stages of genome reduction. Endosymbiotic prokaryotes have evolved diverse strategies for living with reduced gene sets inside a host-defined medium. These include utilization of host-encoded functions (some of them coded by genes acquired by gene transfer from the endosymbiont and/or other bacteria; metabolic complementation between co-symbionts; and forming consortiums with other bacteria within the host. Recent genome sequencing projects of intracellular mutualistic bacteria showed that previously believed universal evolutionary trends like reduced G+C content and conservation of genome synteny are not always present in highly reduced genomes. Finally, the simplified molecular machinery of some of these organisms with small genomes may be used to aid in the design of artificial minimal cells. Here we review recent genomic discoveries of the biology of prokaryotes endowed with small gene sets and discuss the evolutionary mechanisms that have been proposed to explain their peculiar nature.

Joint convention on the safety of spent fuel management and on the safety of radioactive waste management. First national report on the implementation by France of the obligations of the Convention

International Nuclear Information System (INIS)

2003-03-01

The Joint Convention on the safety of spent fuel management and on the safety of radioactive waste management is supplementing the Convention of Nuclear Safety. it was approved by France on february 22, 2000 and it entered into force on June 18,2001. Article 32 obliges each contracting Party to present at the review meetings (every three years) a report on the way in which it implements the obligations of the Convention (full text of the Convention and additional information on the web site of the IAEA, its director General being the depository of the Convention. (author)

Facultative and obligate methanotrophs how to identify and differentiate them.

Science.gov (United States)

Dedysh, Svetlana N; Dunfield, Peter F

2011-01-01

Aerobic methanotrophs are metabolically unique bacteria that are able to utilize methane and some other C1-compounds as sole sources of carbon and energy. A defining characteristic of these organisms is the use of methane monooxygenase (MMO) enzymes to catalyze the oxidation of methane to methanol. For a long time, all methanotrophs were considered to be obligately methylotrophic, that is, unable to grow on compounds containing C-C bonds. This notion has recently been revised. Some members of the genera Methylocella, Methylocystis, and Methylocapsa are now known to be facultative methanotrophs, that is, capable of growing on methane as well as on some multicarbon substrates. The diagnosis of facultative methanotrophy in new isolates requires a great degree of caution since methanotrophic cultures are frequently contaminated by heterotrophic bacteria that survive on metabolic by-products of methanotrophs. The presence of only a few satellite cells in a culture may lead to false conclusions regarding substrate utilization, and several early reports of facultative methanotrophy are likely attributable to impure cultures. Another recurring mistake is the misidentification of nonmethanotrophic facultative methylotrophs as facultative methanotrophs. This chapter was prepared as an aid to avoid both kinds of confusion when examining methanotrophic isolates. Copyright © 2011 Elsevier Inc. All rights reserved.

Climate warming and the potential extinction of fig wasps, the obligate pollinators of figs.

Science.gov (United States)

Jevanandam, Nanthinee; Goh, Alexander G R; Corlett, Richard T

2013-06-23

Figs (Ficus) have a reciprocally obligate mutualism with tiny, short-lived (1-2 days) fig wasps (Agaonidae). The small size and short life of these pollinators is expected to make them more vulnerable to climate change than their larger and longer-lived hosts. We experimentally tested the thermal tolerances of four species of adult female fig wasp from equatorial Singapore. The results suggest that an increase of 3°C or more above the current temperatures experienced across much of the equatorial tropics would markedly decrease the active adult lifespan of all four species. Fig plants are the centre of an intricate web of specialist and generalist animals. Unless fig wasps can acclimate or adapt to warmer temperatures in time, these responses may disrupt the mutualism, potentially affecting multiple trophic levels.

Sustainability requirements in EU public and private procurement – a right or an obligation

DEFF Research Database (Denmark)

Andrecka, Marta; Peterkova, Katerina

2017-01-01

procurement. This is true both for the public and private sectors. However, there is only limited legal regulation of sustainable procurement, which causes many uncertainties in respect to the possibility to include sustainability concerns into procurement processes as well as consequences of (not) doing so...... and private procurement and similarities and differences between the sectors are identified. We find that in both sectors sustainability topics (i) are increasingly considered and implemented into contracts; (ii) deal with similar issues in both contexts; (iii) cover issues that are linked to the subject....... Still, it is found that while there is a right to include sustainability considerations into both public and private procurement processes, there are only contours of the legal obligation to do so. In respect to private procurement, the right to give considerations to sustainability issues...

The Genome Sequence of the Leaf-Cutter Ant Atta cephalotes Reveals Insights into Its Obligate Symbiotic Lifestyle

Science.gov (United States)

Suen, Garret; Holt, Carson; Abouheif, Ehab; Bornberg-Bauer, Erich; Bouffard, Pascal; Caldera, Eric J.; Cash, Elizabeth; Cavanaugh, Amy; Denas, Olgert; Elhaik, Eran; Favé, Marie-Julie; Gadau, Jürgen; Gibson, Joshua D.; Graur, Dan; Grubbs, Kirk J.; Hagen, Darren E.; Harkins, Timothy T.; Helmkampf, Martin; Hu, Hao; Johnson, Brian R.; Kim, Jay; Marsh, Sarah E.; Moeller, Joseph A.; Muñoz-Torres, Mónica C.; Murphy, Marguerite C.; Naughton, Meredith C.; Nigam, Surabhi; Overson, Rick; Rajakumar, Rajendhran; Reese, Justin T.; Scott, Jarrod J.; Smith, Chris R.; Tao, Shu; Tsutsui, Neil D.; Viljakainen, Lumi; Wissler, Lothar; Yandell, Mark D.; Zimmer, Fabian; Taylor, James; Slater, Steven C.; Clifton, Sandra W.; Warren, Wesley C.; Elsik, Christine G.; Smith, Christopher D.; Weinstock, George M.; Gerardo, Nicole M.; Currie, Cameron R.

2011-01-01

Leaf-cutter ants are one of the most important herbivorous insects in the Neotropics, harvesting vast quantities of fresh leaf material. The ants use leaves to cultivate a fungus that serves as the colony's primary food source. This obligate ant-fungus mutualism is one of the few occurrences of farming by non-humans and likely facilitated the formation of their massive colonies. Mature leaf-cutter ant colonies contain millions of workers ranging in size from small garden tenders to large soldiers, resulting in one of the most complex polymorphic caste systems within ants. To begin uncovering the genomic underpinnings of this system, we sequenced the genome of Atta cephalotes using 454 pyrosequencing. One prediction from this ant's lifestyle is that it has undergone genetic modifications that reflect its obligate dependence on the fungus for nutrients. Analysis of this genome sequence is consistent with this hypothesis, as we find evidence for reductions in genes related to nutrient acquisition. These include extensive reductions in serine proteases (which are likely unnecessary because proteolysis is not a primary mechanism used to process nutrients obtained from the fungus), a loss of genes involved in arginine biosynthesis (suggesting that this amino acid is obtained from the fungus), and the absence of a hexamerin (which sequesters amino acids during larval development in other insects). Following recent reports of genome sequences from other insects that engage in symbioses with beneficial microbes, the A. cephalotes genome provides new insights into the symbiotic lifestyle of this ant and advances our understanding of host–microbe symbioses. PMID:21347285

The genome sequence of the leaf-cutter ant Atta cephalotes reveals insights into its obligate symbiotic lifestyle.

Directory of Open Access Journals (Sweden)

Garret Suen

2011-02-01

Full Text Available Leaf-cutter ants are one of the most important herbivorous insects in the Neotropics, harvesting vast quantities of fresh leaf material. The ants use leaves to cultivate a fungus that serves as the colony's primary food source. This obligate ant-fungus mutualism is one of the few occurrences of farming by non-humans and likely facilitated the formation of their massive colonies. Mature leaf-cutter ant colonies contain millions of workers ranging in size from small garden tenders to large soldiers, resulting in one of the most complex polymorphic caste systems within ants. To begin uncovering the genomic underpinnings of this system, we sequenced the genome of Atta cephalotes using 454 pyrosequencing. One prediction from this ant's lifestyle is that it has undergone genetic modifications that reflect its obligate dependence on the fungus for nutrients. Analysis of this genome sequence is consistent with this hypothesis, as we find evidence for reductions in genes related to nutrient acquisition. These include extensive reductions in serine proteases (which are likely unnecessary because proteolysis is not a primary mechanism used to process nutrients obtained from the fungus, a loss of genes involved in arginine biosynthesis (suggesting that this amino acid is obtained from the fungus, and the absence of a hexamerin (which sequesters amino acids during larval development in other insects. Following recent reports of genome sequences from other insects that engage in symbioses with beneficial microbes, the A. cephalotes genome provides new insights into the symbiotic lifestyle of this ant and advances our understanding of host-microbe symbioses.

Transboundary river basin management in Europe
Legal instruments to comply with European water management obligations in case of transboundary water pollution and floods

Directory of Open Access Journals (Sweden)

Andrea M. Keessen

2008-12-01

Full Text Available Although modern European water policy follows a river basin approach where Member States have to cooperate in order to achieve a ‘good status’ of their water bodies, the obligations arising from the European water directives are to be achieved by each Member State individually. This situation creates problems when water pollution and water quantity problems cross borders. It is still unclear whether Member States can be held responsible for not achieving objectives due to causes (partly originating abroad. This article describes some of the legal instruments that water authorities have at their disposal to comply with the European water management obligations in case of transboundary water pollution and floods and thus shape transboundary river management. The article describes instruments to create, implement and enforce transboundary cooperation, and addresses the possibility of transboundary compensation if cooperation fails. Here, the focus is on a civil lawsuit before a domestic court.

Fire management, managed relocation, and land conservation options for long-lived obligate seeding plants under global changes in climate, urbanization, and fire regime.

Science.gov (United States)

Bonebrake, Timothy C; Syphard, Alexandra D; Franklin, Janet; Anderson, Kurt E; Akçakaya, H Resit; Mizerek, Toni; Winchell, Clark; Regan, Helen M

2014-08-01

Most species face multiple anthropogenic disruptions. Few studies have quantified the cumulative influence of multiple threats on species of conservation concern, and far fewer have quantified the potential relative value of multiple conservation interventions in light of these threats. We linked spatial distribution and population viability models to explore conservation interventions under projected climate change, urbanization, and changes in fire regime on a long-lived obligate seeding plant species sensitive to high fire frequencies, a dominant plant functional type in many fire-prone ecosystems, including the biodiversity hotspots of Mediterranean-type ecosystems. First, we investigated the relative risk of population decline for plant populations in landscapes with and without land protection under an existing habitat conservation plan. Second, we modeled the effectiveness of relocating both seedlings and seeds from a large patch with predicted declines in habitat area to 2 unoccupied recipient patches with increasing habitat area under 2 projected climate change scenarios. Finally, we modeled 8 fire return intervals (FRIs) approximating the outcomes of different management strategies that effectively control fire frequency. Invariably, long-lived obligate seeding populations remained viable only when FRIs were maintained at or above a minimum level. Land conservation and seedling relocation efforts lessened the impact of climate change and land-use change on obligate seeding populations to differing degrees depending on the climate change scenario, but neither of these efforts was as generally effective as frequent translocation of seeds. While none of the modeled strategies fully compensated for the effects of land-use and climate change, an integrative approach managing multiple threats may diminish population declines for species in complex landscapes. Conservation plans designed to mitigate the impacts of a single threat are likely to fail if additional

Analisis Budaya Organisasi dan Asimetri Informasi dalam Senjangan Anggaran

Directory of Open Access Journals (Sweden)

Ernawaty Usman

2012-12-01

Full Text Available This study aims to 1 examine the influence of budget participationon budgetary slack. 2 examine the influence organizational culture as anindependent variable, pure or quasi moderation in the relationship between budgetaryparticipation with the budgetary slack. 3 examine the information asymmetryas an independent variable, pure or quasi moderation moderation in the relationshipbetween budgetary participation with the budgetary slack. The method ofanalysis is the field of research and multiple linear regression analysis. The resultsshowed that 1 budget participation has a positive relationship with budgetaryslack. 2. organizational culture is a moderating variable and 3 Information asymmetryas quasi moderating variables.

The first record of a trans-oceanic sister-group relationship between obligate vertebrate troglobites.

Directory of Open Access Journals (Sweden)

Prosanta Chakrabarty

Full Text Available We show using the most complete phylogeny of one of the most species-rich orders of vertebrates (Gobiiformes, and calibrations from the rich fossil record of teleost fishes, that the genus Typhleotris, endemic to subterranean karst habitats in southwestern Madagascar, is the sister group to Milyeringa, endemic to similar subterranean systems in northwestern Australia. Both groups are eyeless, and our phylogenetic and biogeographic results show that these obligate cave fishes now found on opposite ends of the Indian Ocean (separated by nearly 7,000 km are each others closest relatives and owe their origins to the break up of the southern supercontinent, Gondwana, at the end of the Cretaceous period. Trans-oceanic sister-group relationships are otherwise unknown between blind, cave-adapted vertebrates and our results provide an extraordinary case of Gondwanan vicariance.

Reconciling the expectations of community participants with the requirements of non-fossil fuel obligation: the experience of Harlock Hill windfarm

International Nuclear Information System (INIS)

Harrop, J.

1998-01-01

Is it possible to reconcile the aspirations of community participants in a wind energy project with the requirements imposed by the Non-Fossil Fuel Obligation legislation and procedure? This paper considers the practical experience of the framework that was adopted at Harlock Hill wind farm for community participation and the legal structure that were required to ensure that the project retained the full benefit of the premium price arrangements with the Non-Fossil Purchasing Agency Limited. (Author)

Methylobacillus pratensis sp. nov., a novel non-pigmented, aerobic, obligately methylotrophic bacterium isolated from meadow grass.

Science.gov (United States)

Doronina, Nina V; Trotsenko, Yuri A; Kolganova, Tatjana V; Tourova, Tatjana P; Salkinoja-Salonen, Mirja S

2004-09-01

Strain F31T was isolated from meadow grass (Poa trivialis L.) sampled from the city park in Helsinki. Analysis of phenotypic and genotypic properties showed the strain to be related to the group of obligately methylotrophic non-methane utilizing bacteria (methylobacteria) with the ribulose monophosphate pathway of formaldehyde assimilation. Phylogenetic analysis showed the strain to be closely related to the genus Methylobacillus, and analysis of fatty acid composition confirmed this association. Thus, on the basis of its genotypic and phenotypic properties, the isolate is proposed as a novel species of the genus Methylobacillus, Methylobacillus pratensis sp. nov., with F31T as the type strain (= VKM B-2247T = NCIMB 13994T).

DOING BUSINESS IN ROMANIA - PART II: THE PARADIGM OF THE (UNLIMITED LIABILITY OF THE ENTREPRENEUR FOR THE PROFESSIONAL OBLIGATIONS OF THE TYPES OF ENTITIES WITHOUT LEGAL PERSONALITY

Directory of Open Access Journals (Sweden)

Rodica Diana APAN

2014-12-01

Full Text Available The present study focuses on the analysis of the legal status of the affectation patrimony of the registered sole trader authorised to carry out trading activity as well as that of the simple partnership. Representing a distinct part of assets within the individual's own patrimony, the affectation patrimony attract the segregation of the professional creditors who can pursue the assets mainly for the professional obligations. But the effect of constituting the affectation patrimony is not that of preventing the creditors to pursue the other properties within the individual's own assets in the case where they have not been satiated from the affectation patrimony. We conclude that the patrimony of the persons that form a partnership from the individual type of business are exposed up to various degrees to be being pursued for the obligations towards the third parties.