QSPR using MOLGEN-QSPR: the challenge of fluoroalkane boiling points.

Science.gov (United States)

Rücker, Christoph; Meringer, Markus; Kerber, Adalbert

2005-01-01

By means of the new software MOLGEN-QSPR, a multilinear regression model for the boiling points of lower fluoroalkanes is established. The model is based exclusively on simple descriptors derived directly from molecular structure and nevertheless describes a broader set of data more precisely than previous attempts that used either more demanding (quantum chemical) descriptors or more demanding (nonlinear) statistical methods such as neural networks. The model's internal consistency was confirmed by leave-one-out cross-validation. The model was used to predict all unknown boiling points of fluorobutanes, and the quality of predictions was estimated by means of comparison with boiling point predictions for fluoropentanes.

Rationalizing fragment based drug discovery for BACE1: insights from FB-QSAR, FB-QSSR, multi objective (MO-QSPR) and MIF studies.

Science.gov (United States)

Manoharan, Prabu; Vijayan, R S K; Ghoshal, Nanda

2010-10-01

The ability to identify fragments that interact with a biological target is a key step in FBDD. To date, the concept of fragment based drug design (FBDD) is increasingly driven by bio-physical methods. To expand the boundaries of QSAR paradigm, and to rationalize FBDD using In silico approach, we propose a fragment based QSAR methodology referred here in as FB-QSAR. The FB-QSAR methodology was validated on a dataset consisting of 52 Hydroxy ethylamine (HEA) inhibitors, disclosed by GlaxoSmithKline Pharmaceuticals as potential anti-Alzheimer agents. To address the issue of target selectivity, a major confounding factor in the development of selective BACE1 inhibitors, FB-QSSR models were developed using the reported off target activity values. A heat map constructed, based on the activity and selectivity profile of the individual R-group fragments, and was in turn used to identify superior R-group fragments. Further, simultaneous optimization of multiple properties, an issue encountered in real-world drug discovery scenario, and often overlooked in QSAR approaches, was addressed using a Multi Objective (MO-QSPR) method that balances properties, based on the defined objectives. MO-QSPR was implemented using Derringer and Suich desirability algorithm to identify the optimal level of independent variables (X) that could confer a trade-off between selectivity and activity. The results obtained from FB-QSAR were further substantiated using MIF (Molecular Interaction Fields) studies. To exemplify the potentials of FB-QSAR and MO-QSPR in a pragmatic fashion, the insights gleaned from the MO-QSPR study was reverse engineered using Inverse-QSAR in a combinatorial fashion to enumerate some prospective novel, potent and selective BACE1 inhibitors.

Rationalizing fragment based drug discovery for BACE1: insights from FB-QSAR, FB-QSSR, multi objective (MO-QSPR) and MIF studies

Science.gov (United States)

Manoharan, Prabu; Vijayan, R. S. K.; Ghoshal, Nanda

2010-10-01

The ability to identify fragments that interact with a biological target is a key step in FBDD. To date, the concept of fragment based drug design (FBDD) is increasingly driven by bio-physical methods. To expand the boundaries of QSAR paradigm, and to rationalize FBDD using In silico approach, we propose a fragment based QSAR methodology referred here in as FB-QSAR. The FB-QSAR methodology was validated on a dataset consisting of 52 Hydroxy ethylamine (HEA) inhibitors, disclosed by GlaxoSmithKline Pharmaceuticals as potential anti-Alzheimer agents. To address the issue of target selectivity, a major confounding factor in the development of selective BACE1 inhibitors, FB-QSSR models were developed using the reported off target activity values. A heat map constructed, based on the activity and selectivity profile of the individual R-group fragments, and was in turn used to identify superior R-group fragments. Further, simultaneous optimization of multiple properties, an issue encountered in real-world drug discovery scenario, and often overlooked in QSAR approaches, was addressed using a Multi Objective (MO-QSPR) method that balances properties, based on the defined objectives. MO-QSPR was implemented using Derringer and Suich desirability algorithm to identify the optimal level of independent variables ( X) that could confer a trade-off between selectivity and activity. The results obtained from FB-QSAR were further substantiated using MIF (Molecular Interaction Fields) studies. To exemplify the potentials of FB-QSAR and MO-QSPR in a pragmatic fashion, the insights gleaned from the MO-QSPR study was reverse engineered using Inverse-QSAR in a combinatorial fashion to enumerate some prospective novel, potent and selective BACE1 inhibitors.

Random Forest Approach to QSPR Study of Fluorescence Properties Combining Quantum Chemical Descriptors and Solvent Conditions.

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Chen, Chia-Hsiu; Tanaka, Kenichi; Funatsu, Kimito

2018-04-22

The Quantitative Structure - Property Relationship (QSPR) approach was performed to study the fluorescence absorption wavelengths and emission wavelengths of 413 fluorescent dyes in different solvent conditions. The dyes included the chromophore derivatives of cyanine, xanthene, coumarin, pyrene, naphthalene, anthracene and etc., with the wavelength ranging from 250 nm to 800 nm. An ensemble method, random forest (RF), was employed to construct nonlinear prediction models compared with the results of linear partial least squares and nonlinear support vector machine regression models. Quantum chemical descriptors derived from density functional theory method and solvent information were also used by constructing models. The best prediction results were obtained from RF model, with the squared correlation coefficients [Formula: see text] of 0.940 and 0.905 for λ abs and λ em , respectively. The descriptors used in the models were discussed in detail in this report by comparing the feature importance of RF.

2D Quantitative Structure-Property Relationship Study of Mycotoxins by Multiple Linear Regression and Support Vector Machine

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Fereshteh Shiri

2010-08-01

Full Text Available In the present work, support vector machines (SVMs and multiple linear regression (MLR techniques were used for quantitative structure–property relationship (QSPR studies of retention time (tR in standardized liquid chromatography–UV–mass spectrometry of 67 mycotoxins (aflatoxins, trichothecenes, roquefortines and ochratoxins based on molecular descriptors calculated from the optimized 3D structures. By applying missing value, zero and multicollinearity tests with a cutoff value of 0.95, and genetic algorithm method of variable selection, the most relevant descriptors were selected to build QSPR models. MLRand SVMs methods were employed to build QSPR models. The robustness of the QSPR models was characterized by the statistical validation and applicability domain (AD. The prediction results from the MLR and SVM models are in good agreement with the experimental values. The correlation and predictability measure by r2 and q2 are 0.931 and 0.932, repectively, for SVM and 0.923 and 0.915, respectively, for MLR. The applicability domain of the model was investigated using William’s plot. The effects of different descriptors on the retention times are described.

CADASTER QSPR Models for Predictions of Melting and Boiling Points of Perfluorinated Chemicals.

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Bhhatarai, Barun; Teetz, Wolfram; Liu, Tao; Öberg, Tomas; Jeliazkova, Nina; Kochev, Nikolay; Pukalov, Ognyan; Tetko, Igor V; Kovarich, Simona; Papa, Ester; Gramatica, Paola

2011-03-14

Quantitative structure property relationship (QSPR) studies on per- and polyfluorinated chemicals (PFCs) on melting point (MP) and boiling point (BP) are presented. The training and prediction chemicals used for developing and validating the models were selected from Syracuse PhysProp database and literatures. The available experimental data sets were split in two different ways: a) random selection on response value, and b) structural similarity verified by self-organizing-map (SOM), in order to propose reliable predictive models, developed only on the training sets and externally verified on the prediction sets. Individual linear and non-linear approaches based models developed by different CADASTER partners on 0D-2D Dragon descriptors, E-state descriptors and fragment based descriptors as well as consensus model and their predictions are presented. In addition, the predictive performance of the developed models was verified on a blind external validation set (EV-set) prepared using PERFORCE database on 15 MP and 25 BP data respectively. This database contains only long chain perfluoro-alkylated chemicals, particularly monitored by regulatory agencies like US-EPA and EU-REACH. QSPR models with internal and external validation on two different external prediction/validation sets and study of applicability-domain highlighting the robustness and high accuracy of the models are discussed. Finally, MPs for additional 303 PFCs and BPs for 271 PFCs were predicted for which experimental measurements are unknown. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Ant colony optimization as a descriptor selection in QSPR modeling: Estimation of the λmax of anthraquinones-based dyes

OpenAIRE

Morteza Atabati; Kobra Zarei; Azam Borhani

2016-01-01

Quantitative structure–property relationship (QSPR) studies based on ant colony optimization (ACO) were carried out for the prediction of λmax of 9,10-anthraquinone derivatives. ACO is a meta-heuristic algorithm, which is derived from the observation of real ants and proposed to feature selection. After optimization of 3D geometry of structures by the semi-empirical quantum-chemical calculation at AM1 level, different descriptors were calculated by the HyperChem and Dragon softwares (1514 des...

The Interplay between QSAR/QSPR Studiesand Partial Order Ranking and Formal Concept Analyses

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Lars Carlsen

2009-04-01

Full Text Available The often observed scarcity of physical-chemical and well as toxicological data hampers the assessment of potentially hazardous chemicals released to the environment. In such cases Quantitative Structure-Activity Relationships/Quantitative Structure-Property Relationships (QSAR/QSPR constitute an obvious alternative for rapidly, effectively and inexpensively generatng missing experimental values. However, typically further treatment of the data appears necessary, e.g., to elucidate the possible relations between the single compounds as well as implications and associations between the various parameters used for the combined characterization of the compounds under investigation. In the present paper the application of QSAR/QSPR in combination with Partial Order Ranking (POR methodologies will be reviewed and new aspects using Formal Concept Analysis (FCA will be introduced. Where POR constitutes an attractive method for, e.g., prioritizing a series of chemical substances based on a simultaneous inclusion of a range of parameters, FCA gives important information on the implications associations between the parameters. The combined approach thus constitutes an attractive method to a preliminary assessment of the impact on environmental and human health by primary pollutants or possibly by a primary pollutant well as a possible suite of transformation subsequent products that may be both persistent in and bioaccumulating and toxic.The present review focus on the environmental – and human health impact by residuals of the rocket fuel 1,1-dimethyl- hydrazine (heptyl and its transformation products as an illustrative example.

Three-dimensional quantitative structure-property relationship (3D-QSPR) models for prediction of thermodynamic properties of polychlorinated biphenyls (PCBs): enthalpy of vaporization.

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Puri, Swati; Chickos, James S; Welsh, William J

2002-01-01

Three-dimensional Quantitative Structure-Property Relationship (QSPR) models have been derived using Comparative Molecular Field Analysis (CoMFA) to correlate the vaporization enthalpies of a representative set of polychlorinated biphenyls (PCBs) at 298.15 K with their CoMFA-calculated physicochemical properties. Various alignment schemes, such as inertial, as is, and atom fit, were employed in this study. The CoMFA models were also developed using different partial charge formalisms, namely, electrostatic potential (ESP) charges and Gasteiger-Marsili (GM) charges. The most predictive model for vaporization enthalpy (Delta(vap)H(m)(298.15 K)), with atom fit alignment and Gasteiger-Marsili charges, yielded r2 values 0.852 (cross-validated) and 0.996 (conventional). The vaporization enthalpies of PCBs increased with the number of chlorine atoms and were found to be larger for the meta- and para-substituted isomers. This model was used to predict Delta(vap)H(m)(298.15 K) of the entire set of 209 PCB congeners.

QSAR, QSPR and QSRR in Terms of 3-D-MoRSE Descriptors for In Silico Screening of Clofibric Acid Analogues.

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Di Tullio, Maurizio; Maccallini, Cristina; Ammazzalorso, Alessandra; Giampietro, Letizia; Amoroso, Rosa; De Filippis, Barbara; Fantacuzzi, Marialuigia; Wiczling, Paweł; Kaliszan, Roman

2012-07-01

A series of 27 analogues of clofibric acid, mostly heteroarylalkanoic derivatives, have been analyzed by a novel high-throughput reversed-phase HPLC method employing combined gradient of eluent's pH and organic modifier content. The such determined hydrophobicity (lipophilicity) parameters, log kw , and acidity constants, pKa , were subjected to multiple regression analysis to get a QSRR (Quantitative StructureRetention Relationships) and a QSPR (Quantitative Structure-Property Relationships) equation, respectively, describing these pharmacokinetics-determining physicochemical parameters in terms of the calculation chemistry derived structural descriptors. The previously determined in vitro log EC50 values - transactivation activity towards PPARα (human Peroxisome Proliferator-Activated Receptor α) - have also been described in a QSAR (Quantitative StructureActivity Relationships) equation in terms of the 3-D-MoRSE descriptors (3D-Molecule Representation of Structures based on Electron diffraction descriptors). The QSAR model derived can serve for an a priori prediction of bioactivity in vitro of any designed analogue, whereas the QSRR and the QSPR models can be used to evaluate lipophilicity and acidity, respectively, of the compounds, and hence to rational guide selection of structures of proper pharmacokinetics. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Ant colony optimization as a descriptor selection in QSPR modeling: Estimation of the λmax of anthraquinones-based dyes

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Morteza Atabati

2016-09-01

Full Text Available Quantitative structure–property relationship (QSPR studies based on ant colony optimization (ACO were carried out for the prediction of λmax of 9,10-anthraquinone derivatives. ACO is a meta-heuristic algorithm, which is derived from the observation of real ants and proposed to feature selection. After optimization of 3D geometry of structures by the semi-empirical quantum-chemical calculation at AM1 level, different descriptors were calculated by the HyperChem and Dragon softwares (1514 descriptors. A major problem of QSPR is the high dimensionality of the descriptor space; therefore, descriptor selection is the most important step. In this paper, an ACO algorithm was used to select the best descriptors. Then selected descriptors were applied for model development using multiple linear regression. The average absolute relative deviation and correlation coefficient for the calibration set were obtained as 3.3% and 0.9591, respectively, while the average absolute relative deviation and correlation coefficient for the prediction set were obtained as 5.0% and 0.9526, respectively. The results showed that the applied procedure is suitable for prediction of λmax of 9,10-anthraquinone derivatives.

Predictive QSPR Modelling for the Second Virial Coefficient of the Pure Organic Compounds.

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Mokshyna, E; Polishchuk, P G; Nedostup, V I; Kuzmin, V E

2015-01-01

In this article we developed a system of the predictive models for the second virial coefficients of the pure compounds. Second virial coefficient is the property derived from the virial equation of state, and is of particular interest as it describes pair intermolecular interactions. The two-layer QSPR models were developed, which exploited the well-known physical equations and allowed us to include this information into traditional QSPR methodology. This shows some new perspectives for work with temperature-dependent properties. It was shown that 2D descriptors can be successfully used for modeling of complex thermodynamic properties like virial coefficients. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

QSPR study of absorption maxima of organic dyes for dye-sensitized solar cells based on 3D descriptors

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Xu, Jie; Zhang, Hui; Wang, Lei; Liang, Guijie; Wang, Luoxin; Shen, Xiaolin; Xu, Weilin

2010-07-01

A quantitative structure-property relationship (QSPR) study was performed for the prediction of the absorption maxima ( λmax) of organic dyes for dye-sensitized solar cells (DSSCs). The entire set of 70 dyes was divided into a training set of 53 dyes and a test set of 17 dyes according to Kennard and Stones algorithm. Three-dimensional (3D) descriptors were calculated to represent the dye molecules. A ten-descriptor model, with a squared correlation coefficient ( R2) of 0.9543 and a standard error of estimation ( s) of 14.7 nm, was produced by using the stepwise multilinear regression analysis (MLRA) on the training set. The reliability of the proposed model was further illustrated using various evaluation techniques: leave-one-out cross-validation procedure, randomization tests, and validation through the external test set. All descriptors involved in the model were derived solely from the chemical structure of the dye molecules, which makes the model very useful to estimate the λmax of dyes before they are actually synthesized.

Modeling the pH and temperature dependence of aqueousphase hydroxyl radical reaction rate constants of organic micropollutants using QSPR approach.

Science.gov (United States)

Gupta, Shikha; Basant, Nikita

2017-11-01

Designing of advanced oxidation process (AOP) requires knowledge of the aqueous phase hydroxyl radical ( ● OH) reactions rate constants (k OH ), which are strictly dependent upon the pH and temperature of the medium. In this study, pH- and temperature-dependent quantitative structure-property relationship (QSPR) models based on the decision tree boost (DTB) approach were developed for the prediction of k OH of diverse organic contaminants following the OECD guidelines. Experimental datasets (n = 958) pertaining to the k OH values of aqueous phase reactions at different pH (n = 470; 1.4 × 10 6 to 3.8 × 10 10  M -1  s -1 ) and temperature (n = 171; 1.0 × 10 7 to 2.6 × 10 10  M -1  s -1 ) were considered and molecular descriptors of the compounds were derived. The Sanderson scale electronegativity, topological polar surface area, number of double bonds, and halogen atoms in the molecule, in addition to the pH and temperature, were found to be the relevant predictors. The models were validated and their external predictivity was evaluated in terms of most stringent criteria parameters derived on the test data. High values of the coefficient of determination (R 2 ) and small root mean squared error (RMSE) in respective training (> 0.972, ≤ 0.12) and test (≥ 0.936, ≤ 0.16) sets indicated high generalization and predictivity of the developed QSPR model. Other statistical parameters derived from the training and test data also supported the robustness of the models and their suitability for screening new chemicals within the defined chemical space. The developed QSPR models provide a valuable tool for predicting the ● OH reaction rate constants of emerging new water contaminants for their susceptibility to AOPs.

Characterization of Mixtures. Part 2: QSPR Models for Prediction of Excess Molar Volume and Liquid Density Using Neural Networks.

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Ajmani, Subhash; Rogers, Stephen C; Barley, Mark H; Burgess, Andrew N; Livingstone, David J

2010-09-17

In our earlier work, we have demonstrated that it is possible to characterize binary mixtures using single component descriptors by applying various mixing rules. We also showed that these methods were successful in building predictive QSPR models to study various mixture properties of interest. Here in, we developed a QSPR model of an excess thermodynamic property of binary mixtures i.e. excess molar volume (V(E) ). In the present study, we use a set of mixture descriptors which we earlier designed to specifically account for intermolecular interactions between the components of a mixture and applied successfully to the prediction of infinite-dilution activity coefficients using neural networks (part 1 of this series). We obtain a significant QSPR model for the prediction of excess molar volume (V(E) ) using consensus neural networks and five mixture descriptors. We find that hydrogen bond and thermodynamic descriptors are the most important in determining excess molar volume (V(E) ), which is in line with the theory of intermolecular forces governing excess mixture properties. The results also suggest that the mixture descriptors utilized herein may be sufficient to model a wide variety of properties of binary and possibly even more complex mixtures. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

General theory for multiple input-output perturbations in complex molecular systems. 1. Linear QSPR electronegativity models in physical, organic, and medicinal chemistry.

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González-Díaz, Humberto; Arrasate, Sonia; Gómez-SanJuan, Asier; Sotomayor, Nuria; Lete, Esther; Besada-Porto, Lina; Ruso, Juan M

2013-01-01

In general perturbation methods starts with a known exact solution of a problem and add "small" variation terms in order to approach to a solution for a related problem without known exact solution. Perturbation theory has been widely used in almost all areas of science. Bhor's quantum model, Heisenberg's matrix mechanincs, Feyman diagrams, and Poincare's chaos model or "butterfly effect" in complex systems are examples of perturbation theories. On the other hand, the study of Quantitative Structure-Property Relationships (QSPR) in molecular complex systems is an ideal area for the application of perturbation theory. There are several problems with exact experimental solutions (new chemical reactions, physicochemical properties, drug activity and distribution, metabolic networks, etc.) in public databases like CHEMBL. However, in all these cases, we have an even larger list of related problems without known solutions. We need to know the change in all these properties after a perturbation of initial boundary conditions. It means, when we test large sets of similar, but different, compounds and/or chemical reactions under the slightly different conditions (temperature, time, solvents, enzymes, assays, protein targets, tissues, partition systems, organisms, etc.). However, to the best of our knowledge, there is no QSPR general-purpose perturbation theory to solve this problem. In this work, firstly we review general aspects and applications of both perturbation theory and QSPR models. Secondly, we formulate a general-purpose perturbation theory for multiple-boundary QSPR problems. Last, we develop three new QSPR-Perturbation theory models. The first model classify correctly >100,000 pairs of intra-molecular carbolithiations with 75-95% of Accuracy (Ac), Sensitivity (Sn), and Specificity (Sp). The model predicts probabilities of variations in the yield and enantiomeric excess of reactions due to at least one perturbation in boundary conditions (solvent, temperature

QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES.

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Toropov, A A; Toropova, A P; Raska, I

2008-04-01

Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and organic compounds of different classes by optimal descriptors. Statistical characteristics of the best model (vitamins) are the following: n=17, R(2)=0.9841, s=0.634, F=931 (training set); n=7, R(2)=0.9928, s=0.773, F=690 (test set). Using this approach for modeling octanol/water partition coefficient for a set of organic compounds gives a model that is statistically characterized by n=69, R(2)=0.9872, s=0.156, F=5184 (training set) and n=70, R(2)=0.9841, s=0.179, F=4195 (test set).

Multi-target QSPR modeling for simultaneous prediction of multiple gas-phase kinetic rate constants of diverse chemicals

Science.gov (United States)

Basant, Nikita; Gupta, Shikha

2018-03-01

The reactions of molecular ozone (O3), hydroxyl (•OH) and nitrate (NO3) radicals are among the major pathways of removal of volatile organic compounds (VOCs) in the atmospheric environment. The gas-phase kinetic rate constants (kO3, kOH, kNO3) are thus, important in assessing the ultimate fate and exposure risk of atmospheric VOCs. Experimental data for rate constants are not available for many emerging VOCs and the computational methods reported so far address a single target modeling only. In this study, we have developed a multi-target (mt) QSPR model for simultaneous prediction of multiple kinetic rate constants (kO3, kOH, kNO3) of diverse organic chemicals considering an experimental data set of VOCs for which values of all the three rate constants are available. The mt-QSPR model identified and used five descriptors related to the molecular size, degree of saturation and electron density in a molecule, which were mechanistically interpretable. These descriptors successfully predicted three rate constants simultaneously. The model yielded high correlations (R2 = 0.874-0.924) between the experimental and simultaneously predicted endpoint rate constant (kO3, kOH, kNO3) values in test arrays for all the three systems. The model also passed all the stringent statistical validation tests for external predictivity. The proposed multi-target QSPR model can be successfully used for predicting reactivity of new VOCs simultaneously for their exposure risk assessment.

Prediction of boiling points of organic compounds by QSPR tools.

Science.gov (United States)

Dai, Yi-min; Zhu, Zhi-ping; Cao, Zhong; Zhang, Yue-fei; Zeng, Ju-lan; Li, Xun

2013-07-01

The novel electro-negativity topological descriptors of YC, WC were derived from molecular structure by equilibrium electro-negativity of atom and relative bond length of molecule. The quantitative structure-property relationships (QSPR) between descriptors of YC, WC as well as path number parameter P3 and the normal boiling points of 80 alkanes, 65 unsaturated hydrocarbons and 70 alcohols were obtained separately. The high-quality prediction models were evidenced by coefficient of determination (R(2)), the standard error (S), average absolute errors (AAE) and predictive parameters (Qext(2),RCV(2),Rm(2)). According to the regression equations, the influences of the length of carbon backbone, the size, the degree of branching of a molecule and the role of functional groups on the normal boiling point were analyzed. Comparison results with reference models demonstrated that novel topological descriptors based on the equilibrium electro-negativity of atom and the relative bond length were useful molecular descriptors for predicting the normal boiling points of organic compounds. Copyright © 2013 Elsevier Inc. All rights reserved.

Potentialities and limits of QSPR and molecular modeling in the design of the extraction solvents used in hydrometallurgy

International Nuclear Information System (INIS)

Cote, G.; Chagnes, A.

2010-01-01

Due to new challenges, new extraction solvents based on innovative extractants are needed in hydrometallurgy for specific tasks. Thus, the aim of the present paper is to discuss the potentialities and limits of QSPR and molecular modeling for identifying new extractants. QSPR methods may have useful applications in such a complex problem as the design of ligands for metal separation. Nevertheless, the degree of reliability of the predictions is still limited and, in the present state of the art, these techniques are likely more useful for optimization within a given family of extractants than to build in silico new reagents. The molecular modeling techniques provide binding energies between target metals and given ligands, as well as optimized chemical structures of the formed complexes. Thus, in principle, the information which can be deduced from the molecular modeling computations is richer than that provided by QSPR methods. Nevertheless, an effort should be made to establish more tangible links between the calculated binding energies and the physical parameters used by the hydrometallurgists, such as the complexation constants in aqueous phase (β MAn ) or better the extraction constants (K ex ). (author)

Quantitative Structure–Property Relationship (QSPR Models for a Local Quantum Descriptor: Investigation of the 4- and 3-Substituted-Cinnamic Acid Esterification

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Cláudio E. Rodrigues-Santos

2015-09-01

Full Text Available In this work, the theoretical description of the 4- and 3-substituted-cinnamic acid esterification with different electron donating and electron withdrawing groups was performed at the B3LYP and M06-2X levels, as a two-step process: the O-protonation and the nucleophile attack by ethanol. In parallel, an experimental work devoted to the synthesis and characterization of the substituted-cinnamate esters has also been performed. In order to quantify the substituents effects, quantitative structure–property relationship (QSPR models based on the atomic charges, Fukui functions and the Frontier Effective-for-Reaction Molecular Orbitals (FERMO energies were investigated. In fact, the Fukui functions, ƒ+C and ƒ−O, indicated poor correlations for each individual step, and in contrast with the general literature, the O-protonation step is affected both by the FERMO energies and the O-charges of the carbonyl group. Since the process was shown to not be totally described by either charge- or frontier-orbitals, it is proposed to be frontier-charge-miscere controlled. Moreover, the observed trend for the experimental reaction yields suggests that the electron withdrawing groups favor the reaction and the same was observed for Step 2, which can thus be pointed out as the determining step.

Excited States and Photodebromination of Selected Polybrominated Diphenyl Ethers: Computational and Quantitative Structure—Property Relationship Studies

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Jin Luo

2015-01-01

Full Text Available This paper presents a density functional theory (DFT/time-dependent DFT (TD-DFT study on the lowest lying singlet and triplet excited states of 20 selected polybrominateddiphenyl ether (PBDE congeners, with the solvation effect included in the calculations using the polarized continuum model (PCM. The results obtained showed that for most of the brominated diphenyl ether (BDE congeners, the lowest singlet excited state was initiated by the electron transfer from HOMO to LUMO, involving a π–σ* excitation. In triplet excited states, structure of the BDE congeners differed notably from that of the BDE ground states with one of the specific C–Br bonds bending off the aromatic plane. In addition, the partial least squares regression (PLSR, principal component analysis-multiple linear regression analysis (PCA-MLR, and back propagation artificial neural network (BP-ANN approaches were employed for a quantitative structure-property relationship (QSPR study. Based on the previously reported kinetic data for the debromination by ultraviolet (UV and sunlight, obtained QSPR models exhibited a reasonable evaluation of the photodebromination reactivity even when the BDE congeners had same degree of bromination, albeit different patterns of bromination.

Solvent Extraction and QSPR of Catecholamines with a Bis(2-ethlhexyl) Hydrogen Phosphate

Energy Technology Data Exchange (ETDEWEB)

Yoshizuka, Kazuharu.; Fujimoto, Yuko.; Ota, Keisuke.; Inoue, Katsutoshi. [Saga University, Saga (Japan). Dept. of Applied Chemistry

1999-02-01

In order to develop an effective separation recess for catecholamine (CA), a basic investigation on solvent extraction of dopamine (DA), adrenaline (Ad) and noradrenaline (NA) from hydrochloric acid solution and their stripping is conducted at 30 degree C employing bis(2-ethylhexyl) hydrogen phosphate (D2EHPA) in chloroform, n-hexane and toluene as the organic diluents. From the dependencies of the distribution ratios on the concentrations of reactant species, i.e. CA, hydrogen ion and D2EHPA, it is elucidated that CA (RNH{sub 2}) is extracted with D2EHPA (HR`) according to the ion exchange mechanism, as the complex type, RNH{sub 3}R` (HR`){sub 3}, and the equilibrium constants (K{sub ex,CA}) for the extraction reactions are also evaluated. The quantitative structure property relationship (QSPR) of K{sub ex,CA} values for each organic diluent is discussed using molecular modeling with semi-empirical molecular orbital calculations considering the solvent effect. (author)

Field determination and QSPR prediction of equilibrium-status soil/vegetation partition coefficient of PCDD/Fs.

Science.gov (United States)

Li, Li; Wang, Qiang; Qiu, Xinghua; Dong, Yian; Jia, Shenglan; Hu, Jianxin

2014-07-15

Characterizing pseudo equilibrium-status soil/vegetation partition coefficient KSV, the quotient of respective concentrations in soil and vegetation of a certain substance at remote background areas, is essential in ecological risk assessment, however few previous attempts have been made for field determination and developing validated and reproducible structure-based estimates. In this study, KSV was calculated based on measurements of seventeen 2,3,7,8-substituted PCDD/F congeners in soil and moss (Dicranum angustum), and rouzi grass (Thylacospermum caespitosum) of two background sites, Ny-Ålesund of the Arctic and Zhangmu-Nyalam region of the Tibet Plateau, respectively. By both fugacity modeling and stepwise regression of field data, the air-water partition coefficient (KAW) and aqueous solubility (SW) were identified as the influential physicochemical properties. Furthermore, validated quantitative structure-property relationship (QSPR) model was developed to extrapolate the KSV prediction to all 210 PCDD/F congeners. Molecular polarizability, molecular size and molecular energy demonstrated leading effects on KSV. Copyright © 2014 Elsevier B.V. All rights reserved.

Modeling adsorption of brominated, chlorinated and mixed bromo/chloro-dibenzo-p-dioxins on C60 fullerene using Nano-QSPR

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Piotr Urbaszek

2017-03-01

Full Text Available Many technological implementations in the field of nanotechnology have involved carbon nanomaterials, including fullerenes such as the buckminsterfullerene, C60. The unprecedented properties of such organic nanomaterials (in particular their large surface area gained extensive attention for their potential use as organic pollutant sorbents. Sorption interactions can be very hazardous and useful at the same time. This work investigates the influence of halogenation by bromine and/or chlorine in dibenzo-p-dioxins on their sorption ability on the C60 fullerene surface. Halogenated dibenzo-p-dioxins (PXDDs, where X = Br or Cl are ever-present in the environment and accidently produced in many technological processes in only approximately known quantities. If all combinatorial Br and/or Cl dioxin substitution possibilities are present in the environment, the experimental characterization and investigation of sorbent effectiveness is more than difficult. In this work, we have developed a quantitative structure–property relationship (QSPR model (R2 = 0.998, predicting the adsorption energy [kcal/mol] for 1,701 PXDDs adsorbed on C60 (PXDD@C60. Based on the QSPR model reported herein, we concluded that the lowest energy PXDD@C60 complexes are those that the World Health Organization (WHO considers to be less dangerous with respect to the aryl hydrocarbon receptor (AhR toxicity mechanism. Therefore, the effectiveness of fullerenes as sorbent agents may be underestimated as sorption could be less effective for toxic congeners than previously believed.

QSPR models for predicting generator-column-derived octanol/water and octanol/air partition coefficients of polychlorinated biphenyls.

Science.gov (United States)

Yuan, Jintao; Yu, Shuling; Zhang, Ting; Yuan, Xuejie; Cao, Yunyuan; Yu, Xingchen; Yang, Xuan; Yao, Wu

2016-06-01

Octanol/water (K(OW)) and octanol/air (K(OA)) partition coefficients are two important physicochemical properties of organic substances. In current practice, K(OW) and K(OA) values of some polychlorinated biphenyls (PCBs) are measured using generator column method. Quantitative structure-property relationship (QSPR) models can serve as a valuable alternative method of replacing or reducing experimental steps in the determination of K(OW) and K(OA). In this paper, two different methods, i.e., multiple linear regression based on dragon descriptors and hologram quantitative structure-activity relationship, were used to predict generator-column-derived log K(OW) and log K(OA) values of PCBs. The predictive ability of the developed models was validated using a test set, and the performances of all generated models were compared with those of three previously reported models. All results indicated that the proposed models were robust and satisfactory and can thus be used as alternative models for the rapid assessment of the K(OW) and K(OA) of PCBs. Copyright © 2016 Elsevier Inc. All rights reserved.

Prediction of the maximum absorption wavelength of azobenzene dyes by QSPR tools

Science.gov (United States)

Xu, Xuan; Luan, Feng; Liu, Huitao; Cheng, Jianbo; Zhang, Xiaoyun

2011-12-01

The maximum absorption wavelength ( λmax) of a large data set of 191 azobenzene dyes was predicted by quantitative structure-property relationship (QSPR) tools. The λmax was correlated with the 4 molecular descriptors calculated from the structure of the dyes alone. The multiple linear regression method (MLR) and the non-linear radial basis function neural network (RBFNN) method were applied to develop the models. The statistical parameters provided by the MLR model were R2 = 0.893, Radj2=0.893, qLOO2=0.884, F = 1214.871, RMS = 11.6430 for the training set; and R2 = 0.849, Radj2=0.845, qext2=0.846, F = 207.812, RMS = 14.0919 for the external test set. The RBFNN model gave even improved statistical results: R2 = 0.920, Radj2=0.919, qLOO2=0.898, F = 1664.074, RMS = 9.9215 for the training set, and R2 = 0.895, Radj2=0.892, qext2=0.895, F = 314.256, RMS = 11.6427 for the external test set. This theoretical method provides a simple, precise and an alternative method to obtain λmax of azobenzene dyes.

Quantitative relationships for the prediction of the vapor pressure of some hydrocarbons from the van der Waals molecular surface

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Olariu Tudor

2015-01-01

Full Text Available A quantitative structure - property relationship (QSPR modeling of vapor pressure at 298.15 K, expressed as log (VP / Pa was performed for a series of 84 hydrocarbons (63 alkanes and 21 cycloalkanes using the van der Waals (vdW surface area, SW/Å2, calculated by the Monte Carlo method, as the molecular descriptor. The QSPR model developed from the subset of 63 alkanes (C1-C16, deemed as the training set, was successfully used for the prediction of the log (VP / Pa values of the 21 cycloalkanes, which was the external prediction (test subset. A QSPR model was also developed for a series composed of all 84 hydrocarbons. Both QSPR models were statistically tested for their ability to fit the data and for prediction. The results showed that the vdW molecular surface used as molecular descriptor (MD explains the variance of the majority of the log (VP / Pa values in this series of 84 hydrocarbons. This MD describes very well the intermolecular forces that hold neutral molecules together. The clear physical meaning of the molecular surface values, SW/Å2, could explain the success of the QSPR models obtained with a single structural molecular descriptor.

PREDICTING THE BOILING POINT OF PCDD/Fs BY THE QSPR METHOD BASED ON THE MOLECULAR DISTANCE-EDGE VECTOR INDEX

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Long Jiao

2015-05-01

Full Text Available The quantitative structure property relationship (QSPR for the boiling point (Tb of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs was investigated. The molecular distance-edge vector (MDEV index was used as the structural descriptor. The quantitative relationship between the MDEV index and Tb was modeled by using multivariate linear regression (MLR and artificial neural network (ANN, respectively. Leave-one-out cross validation and external validation were carried out to assess the prediction performance of the models developed. For the MLR method, the prediction root mean square relative error (RMSRE of leave-one-out cross validation and external validation was 1.77 and 1.23, respectively. For the ANN method, the prediction RMSRE of leave-one-out cross validation and external validation was 1.65 and 1.16, respectively. A quantitative relationship between the MDEV index and Tb of PCDD/Fs was demonstrated. Both MLR and ANN are practicable for modeling this relationship. The MLR model and ANN model developed can be used to predict the Tb of PCDD/Fs. Thus, the Tb of each PCDD/F was predicted by the developed models.

QSPR Models for Predicting Log Pliver Values for Volatile Organic Compounds Combining Statistical Methods and Domain Knowledge

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Mónica F. Díaz

2012-12-01

Full Text Available Volatile organic compounds (VOCs are contained in a variety of chemicals that can be found in household products and may have undesirable effects on health. Thereby, it is important to model blood-to-liver partition coefficients (log Pliver for VOCs in a fast and inexpensive way. In this paper, we present two new quantitative structure-property relationship (QSPR models for the prediction of log Pliver, where we also propose a hybrid approach for the selection of the descriptors. This hybrid methodology combines a machine learning method with a manual selection based on expert knowledge. This allows obtaining a set of descriptors that is interpretable in physicochemical terms. Our regression models were trained using decision trees and neural networks and validated using an external test set. Results show high prediction accuracy compared to previous log Pliver models, and the descriptor selection approach provides a means to get a small set of descriptors that is in agreement with theoretical understanding of the target property.

3D-QSPR Method of Computational Technique Applied on Red Reactive Dyes by Using CoMFA Strategy

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Shahnaz Perveen

2011-12-01

Full Text Available Cellulose fiber is a tremendous natural resource that has broad application in various productions including the textile industry. The dyes, which are commonly used for cellulose printing, are “reactive dyes” because of their high wet fastness and brilliant colors. The interaction of various dyes with the cellulose fiber depends upon the physiochemical properties that are governed by specific features of the dye molecule. The binding pattern of the reactive dye with cellulose fiber is called the ligand-receptor concept. In the current study, the three dimensional quantitative structure property relationship (3D-QSPR technique was applied to understand the red reactive dyes interactions with the cellulose by the Comparative Molecular Field Analysis (CoMFA method. This method was successfully utilized to predict a reliable model. The predicted model gives satisfactory statistical results and in the light of these, it was further analyzed. Additionally, the graphical outcomes (contour maps help us to understand the modification pattern and to correlate the structural changes with respect to the absorptivity. Furthermore, the final selected model has potential to assist in understanding the charachteristics of the external test set. The study could be helpful to design new reactive dyes with better affinity and selectivity for the cellulose fiber.

3D-QSPR method of computational technique applied on red reactive dyes by using CoMFA strategy.

Science.gov (United States)

Mahmood, Uzma; Rashid, Sitara; Ali, S Ishrat; Parveen, Rasheeda; Zaheer-Ul-Haq; Ambreen, Nida; Khan, Khalid Mohammed; Perveen, Shahnaz; Voelter, Wolfgang

2011-01-01

Cellulose fiber is a tremendous natural resource that has broad application in various productions including the textile industry. The dyes, which are commonly used for cellulose printing, are "reactive dyes" because of their high wet fastness and brilliant colors. The interaction of various dyes with the cellulose fiber depends upon the physiochemical properties that are governed by specific features of the dye molecule. The binding pattern of the reactive dye with cellulose fiber is called the ligand-receptor concept. In the current study, the three dimensional quantitative structure property relationship (3D-QSPR) technique was applied to understand the red reactive dyes interactions with the cellulose by the Comparative Molecular Field Analysis (CoMFA) method. This method was successfully utilized to predict a reliable model. The predicted model gives satisfactory statistical results and in the light of these, it was further analyzed. Additionally, the graphical outcomes (contour maps) help us to understand the modification pattern and to correlate the structural changes with respect to the absorptivity. Furthermore, the final selected model has potential to assist in understanding the characteristics of the external test set. The study could be helpful to design new reactive dyes with better affinity and selectivity for the cellulose fiber.

An approach to the interpretation of backpropagation neural network models in QSAR studies.

Science.gov (United States)

Baskin, I I; Ait, A O; Halberstam, N M; Palyulin, V A; Zefirov, N S

2002-03-01

An approach to the interpretation of backpropagation neural network models for quantitative structure-activity and structure-property relationships (QSAR/QSPR) studies is proposed. The method is based on analyzing the first and second moments of distribution of the values of the first and the second partial derivatives of neural network outputs with respect to inputs calculated at data points. The use of such statistics makes it possible not only to obtain actually the same characteristics as for the case of traditional "interpretable" statistical methods, such as the linear regression analysis, but also to reveal important additional information regarding the non-linear character of QSAR/QSPR relationships. The approach is illustrated by an example of interpreting a backpropagation neural network model for predicting position of the long-wave absorption band of cyane dyes.

QSPR models of n-octanol/water partition coefficients and aqueous solubility of halogenated methyl-phenyl ethers by DFT method.

Science.gov (United States)

Zeng, Xiao-Lan; Wang, Hong-Jun; Wang, Yan

2012-02-01

The possible molecular geometries of 134 halogenated methyl-phenyl ethers were optimized at B3LYP/6-31G(*) level with Gaussian 98 program. The calculated structural parameters were taken as theoretical descriptors to establish two new novel QSPR models for predicting aqueous solubility (-lgS(w,l)) and n-octanol/water partition coefficient (lgK(ow)) of halogenated methyl-phenyl ethers. The two models achieved in this work both contain three variables: energy of the lowest unoccupied molecular orbital (E(LUMO)), most positive atomic partial charge in molecule (q(+)), and quadrupole moment (Q(yy) or Q(zz)), of which R values are 0.992 and 0.970 respectively, their standard errors of estimate in modeling (SD) are 0.132 and 0.178, respectively. The results of leave-one-out (LOO) cross-validation for training set and validation with external test sets both show that the models obtained exhibited optimum stability and good predictive power. We suggests that two QSPR models derived here can be used to predict S(w,l) and K(ow) accurately for non-tested halogenated methyl-phenyl ethers congeners. Copyright © 2011 Elsevier Ltd. All rights reserved.

Quantitative structure-property relationship study of n-octanol-water partition coefficients of some of diverse drugs using multiple linear regression

International Nuclear Information System (INIS)

Ghasemi, Jahanbakhsh; Saaidpour, Saadi

2007-01-01

A quantitative structure-property relationship (QSPR) study was performed to develop models those relate the structures of 150 drug organic compounds to their n-octanol-water partition coefficients (log P o/w ). Molecular descriptors derived solely from 3D structures of the molecular drugs. A genetic algorithm was also applied as a variable selection tool in QSPR analysis. The models were constructed using 110 molecules as training set, and predictive ability tested using 40 compounds. Modeling of log P o/w of these compounds as a function of the theoretically derived descriptors was established by multiple linear regression (MLR). Four descriptors for these compounds molecular volume (MV) (geometrical), hydrophilic-lipophilic balance (HLB) (constitutional), hydrogen bond forming ability (HB) (electronic) and polar surface area (PSA) (electrostatic) are taken as inputs for the model. The use of descriptors calculated only from molecular structure eliminates the need for experimental determination of properties for use in the correlation and allows for the estimation of log P o/w for molecules not yet synthesized. Application of the developed model to a testing set of 40 drug organic compounds demonstrates that the model is reliable with good predictive accuracy and simple formulation. The prediction results are in good agreement with the experimental value. The root mean square error of prediction (RMSEP) and square correlation coefficient (R 2 ) for MLR model were 0.22 and 0.99 for the prediction set log P o/w

Considerations of nano-QSAR/QSPR models for nanopesticide risk assessment within the European legislative framework.

Science.gov (United States)

Villaverde, Juan José; Sevilla-Morán, Beatriz; López-Goti, Carmen; Alonso-Prados, José Luis; Sandín-España, Pilar

2018-09-01

The European market for pesticides is currently legislated through the well-developed Regulation (EC) No. 1107/2009. This regulation promotes the competitiveness of European agriculture, recognizing the necessity of safe pesticides for human and animal health and the environment to protect crops against pests, diseases and weeds. In this sense, nanotechnology can provide a tremendous opportunity to achieve a more rational use of pesticides. However, the lack of information regarding nanopesticides and their fate and behavior in the environment and their effects on human and animal health is inhibiting rapid nanopesticide incorporation into European Union agriculture. This review analyzes the recent state of knowledge on nanopesticide risk assessment, highlighting the challenges that need to be overcame to accelerate the arrival of these new tools for plant protection to European agricultural professionals. Novel nano-Quantitative Structure-Activity/Structure-Property Relationship (nano-QSAR/QSPR) tools for risk assessment are analyzed, including modeling methods and validation procedures towards the potential of these computational instruments to meet the current requirements for authorization of nanoformulations. Future trends on these issues, of pressing importance within the context of the current European pesticide legislative framework, are also discussed. Standard protocols to make high-quality and well-described datasets for the series of related but differently sized nanoparticles/nanopesticides are required. Copyright © 2018 Elsevier B.V. All rights reserved.

Rational Formulation of Alternative Fuels using QSPR Methods: Application to Jet Fuels Développement d’un outil d’aide à la formulation des carburants alternatifs utilisant des méthodes QSPR (Quantitative Structure Property Relationship: application aux carburéacteurs

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Saldana D.A.

2013-06-01

Full Text Available Alternative fuels are a promising solution for road transport but also for aircraft. In the aviation field, a huge amount of work has been done in the past years with the approval to use up to 50 % by volume of SPK (Synthetic Paraffinic Kerosene in blends with conventional fossil Jet A-1. SPK are Fischer-Tropsch (FT fuels but also Hydroprocessed Esters and Fatty Acids (HEFA. However, these alternative fuels can have different chemical properties depending on the process used for their production. These properties include normal to iso paraffin ratio, carbon chain length and level of branching. R&D studies of alternative fuels are based on the evaluation of products coming from identified production processes. However, it appears that a better way of studying them could be firstly to determine the best chemical composition regarding aviation problems and secondly to find the best process and finishing process in order to obtain such a product. The objective of this work is to design a tool that aims to guide the future formulation of alternative fuels for aviation through the prediction of targeted physical properties. Thus, it is proposed to apply a methodology that identifies relationships between the structure and properties of a molecule (QSPR for Quantitative Structure Property Relationship, with the aim of establishing predictive models. These models will be built for hydrocarbons (normal and iso paraffins, naphthenes, aromatics, etc. and oxygenated compounds (esters and alcohols. For aviation, oxygenated compounds are not considered as a drop-in fuel. It could be seen as a disruptive solution in a long term view. There are concerns with oxygenates in aviation that are covered in this paper such as the flash point but others such as the energetic content, the water affinity that are not taken into account in this paper. The properties currently studied are flash point, cetane number, density and viscosity. The data sets will contain data

Power Conversion Efficiency of Arylamine Organic Dyes for Dye-Sensitized Solar Cells (DSSCs Explicit to Cobalt Electrolyte: Understanding the Structural Attributes Using a Direct QSPR Approach

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Supratik Kar

2016-12-01

Full Text Available Post silicon solar cell era involves light-absorbing dyes for dye-sensitized solar systems (DSSCs. Therefore, there is great interest in the design of competent organic dyes for DSSCs with high power conversion efficiency (PCE to bypass some of the disadvantages of silicon-based solar cell technologies, such as high cost, heavy weight, limited silicon resources, and production methods that lead to high environmental pollution. The DSSC has the unique feature of a distance-dependent electron transfer step. This depends on the relative position of the sensitized organic dye in the metal oxide composite system. In the present work, we developed quantitative structure-property relationship (QSPR models to set up the quantitative relationship between the overall PCE and quantum chemical molecular descriptors. They were calculated from density functional theory (DFT and time-dependent DFT (TD-DFT methods as well as from DRAGON software. This allows for understanding the basic electron transfer mechanism along with the structural attributes of arylamine-organic dye sensitizers for the DSSCs explicit to cobalt electrolyte. The identified properties and structural fragments are particularly valuable for guiding time-saving synthetic efforts for development of efficient arylamine organic dyes with improved power conversion efficiency.

Estimating persistence of brominated and chlorinated organic pollutants in air, water, soil, and sediments with the QSPR-based classification scheme.

Science.gov (United States)

Puzyn, T; Haranczyk, M; Suzuki, N; Sakurai, T

2011-02-01

We have estimated degradation half-lives of both brominated and chlorinated dibenzo-p-dioxins (PBDDs and PCDDs), furans (PBDFs and PCDFs), biphenyls (PBBs and PCBs), naphthalenes (PBNs and PCNs), diphenyl ethers (PBDEs and PCDEs) as well as selected unsubstituted polycyclic aromatic hydrocarbons (PAHs) in air, surface water, surface soil, and sediments (in total of 1,431 compounds in four compartments). Next, we compared the persistence between chloro- (relatively well-studied) and bromo- (less studied) analogs. The predictions have been performed based on the quantitative structure-property relationship (QSPR) scheme with use of k-nearest neighbors (kNN) classifier and the semi-quantitative system of persistence classes. The classification models utilized principal components derived from the principal component analysis of a set of 24 constitutional and quantum mechanical descriptors as input variables. Accuracies of classification (based on an external validation) were 86, 85, 87, and 75% for air, surface water, surface soil, and sediments, respectively. The persistence of all chlorinated species increased with increasing halogenation degree. In the case of brominated organic pollutants (Br-OPs), the trend was the same for air and sediments. However, we noticed that the opposite trend for persistence in surface water and soil. The results suggest that, due to high photoreactivity of C-Br chemical bonds, photolytic processes occurring in surface water and soil are able to play significant role in transforming and removing Br-OPs from these compartments. This contribution is the first attempt of classifying together Br-OPs and Cl-OPs according to their persistence, in particular, environmental compartments.

Quantitative Structure-Retention Relationships (QSRR) for Chromatographic Separation of Disazo and Trisazo 4,4'-Diaminobenzanilide-based Dyes

OpenAIRE

Funar-Timofei, Simona; Fabian, Walter M. F.; Simu, Georgeta M.; Suzukic, Takahiro

2006-01-01

For a series of 23 disazo and trisazo 4,4'-diaminobenzanilide-based direct dye molecules, thechromatographic mobilities, extrapolated to modifier-free conditions (RM0 values), were determinedfrom reverse-phase thin-layer chromatography (RP-TLC) experiments. Traditional and rational QSAR/QSPR modelling techniques have been applied to find a quantitative structure-retention relationship (QSRR) for the dyes. Molecular dye structures were energy minimized by both molecular mechanics and quantum c...

Advances in the replacement and enhanced replacement method in QSAR and QSPR theories.

Science.gov (United States)

Mercader, Andrew G; Duchowicz, Pablo R; Fernández, Francisco M; Castro, Eduardo A

2011-07-25

The selection of an optimal set of molecular descriptors from a much greater pool of such regression variables is a crucial step in the development of QSAR and QSPR models. The aim of this work is to further improve this important selection process. For this reason three different alternatives for the initial steps of our recently developed enhanced replacement method (ERM) and replacement method (RM) are proposed. These approaches had previously proven to yield near optimal results with a much smaller number of linear regressions than the full search. The algorithms were tested on four different experimental data sets, formed by collections of 116, 200, 78, and 100 experimental records from different compounds and 1268, 1338, 1187, and 1306 molecular descriptors, respectively. The comparisons showed that one of the new alternatives further improves the ERM, which has shown to be superior to genetic algorithms for the selection of an optimal set of molecular descriptors from a much greater pool. The new proposed alternative also improves the simpler and the lower computational demand algorithm RM.

Wavelet neural network modeling in QSPR for prediction of solubility of 25 anthraquinone dyes at different temperatures and pressures in supercritical carbon dioxide.

Science.gov (United States)

Tabaraki, R; Khayamian, T; Ensafi, A A

2006-09-01

A wavelet neural network (WNN) model in quantitative structure property relationship (QSPR) was developed for predicting solubility of 25 anthraquinone dyes in supercritical carbon dioxide over a wide range of pressures (70-770 bar) and temperatures (291-423 K). A large number of descriptors were calculated with Dragon software and a subset of calculated descriptors was selected from 18 classes of Dragon descriptors with a stepwise multiple linear regression (MLR) as a feature selection technique. Six calculated and two experimental descriptors, pressure and temperature, were selected as the most feasible descriptors. The selected descriptors were used as input nodes in a wavelet neural network (WNN) model. The wavelet neural network architecture and its parameters were optimized simultaneously. The data was randomly divided to the training, prediction and validation sets. The predictive ability of the model was evaluated using validation data set. The root mean squares error (RMSE) and mean absolute errors were 0.339 and 0.221, respectively, for the validation data set. The performance of the WNN model was also compared with artificial neural network (ANN) model and the results showed the superiority of the WNN over ANN model.

Event-based criteria in GT-STAF information indices: theory, exploratory diversity analysis and QSPR applications.

Science.gov (United States)

Barigye, S J; Marrero-Ponce, Y; Martínez López, Y; Martínez Santiago, O; Torrens, F; García Domenech, R; Galvez, J

2013-01-01

Versatile event-based approaches for the definition of novel information theory-based indices (IFIs) are presented. An event in this context is the criterion followed in the "discovery" of molecular substructures, which in turn serve as basis for the construction of the generalized incidence and relations frequency matrices, Q and F, respectively. From the resultant F, Shannon's, mutual, conditional and joint entropy-based IFIs are computed. In previous reports, an event named connected subgraphs was presented. The present study is an extension of this notion, in which we introduce other events, namely: terminal paths, vertex path incidence, quantum subgraphs, walks of length k, Sach's subgraphs, MACCs, E-state and substructure fingerprints and, finally, Ghose and Crippen atom-types for hydrophobicity and refractivity. Moreover, we define magnitude-based IFIs, introducing the use of the magnitude criterion in the definition of mutual, conditional and joint entropy-based IFIs. We also discuss the use of information-theoretic parameters as a measure of the dissimilarity of codified structural information of molecules. Finally, a comparison of the statistics for QSPR models obtained with the proposed IFIs and DRAGON's molecular descriptors for two physicochemical properties log P and log K of 34 derivatives of 2-furylethylenes demonstrates similar to better predictive ability than the latter.

Quantitative structure-property relationships for octanol-water partition coefficients of polybrominated diphenyl ethers.

Science.gov (United States)

Li, Linnan; Xie, Shaodong; Cai, Hao; Bai, Xuetao; Xue, Zhao

2008-08-01

Theoretical molecular descriptors were tested against logK(OW) values for polybrominated diphenyl ethers (PBDEs) using the Partial Least-Squares Regression method which can be used to analyze data with many variables and few observations. A quantitative structure-property relationship (QSPR) model was successfully developed with a high cross-validated value (Q(cum)(2)) of 0.961, indicating a good predictive ability and stability of the model. The predictive power of the QSPR model was further cross-validated. The values of logK(OW) for PBDEs are mainly governed by molecular surface area, energy of the lowest unoccupied molecular orbital and the net atomic charges on the oxygen atom. All these descriptors have been discussed to interpret the partitioning mechanism of PBDE chemicals. The bulk property of the molecules represented by molecular surface area is the leading factor, and K(OW) values increase with the increase of molecular surface area. Higher energy of the lowest unoccupied molecular orbital and higher net atomic charge on the oxygen atom of PBDEs result in smaller K(OW). The energy of the lowest unoccupied molecular orbital and the net atomic charge on PBDEs oxygen also play important roles in affecting the partition of PBDEs between octanol and water by influencing the interactions between PBDEs and solvent molecules.

Molecular structure-adsorption study on current textile dyes.

Science.gov (United States)

Örücü, E; Tugcu, G; Saçan, M T

2014-01-01

This study was performed to investigate the adsorption of a diverse set of textile dyes onto granulated activated carbon (GAC). The adsorption experiments were carried out in a batch system. The Langmuir and Freundlich isotherm models were applied to experimental data and the isotherm constants were calculated for 33 anthraquinone and azo dyes. The adsorption equilibrium data fitted more adequately to the Langmuir isotherm model than the Freundlich isotherm model. Added to a qualitative analysis of experimental results, multiple linear regression (MLR), support vector regression (SVR) and back propagation neural network (BPNN) methods were used to develop quantitative structure-property relationship (QSPR) models with the novel adsorption data. The data were divided randomly into training and test sets. The predictive ability of all models was evaluated using the test set. Descriptors were selected with a genetic algorithm (GA) using QSARINS software. Results related to QSPR models on the adsorption capacity of GAC showed that molecular structure of dyes was represented by ionization potential based on two-dimensional topological distances, chromophoric features and a property filter index. Comparison of the performance of the models demonstrated the superiority of the BPNN over GA-MLR and SVR models.

Adsorption of s-triazines onto polybenzimidazole: A quantitative structure-property relationship investigation

Energy Technology Data Exchange (ETDEWEB)

D' Archivio, Angelo Antonio, E-mail: angeloantonio.darchivio@univaq.it [Dipartimento di Chimica, Ingegneria Chimica e Materiali, Universita degli Studi dell' Aquila, Via Vetoio, 67010 Coppito, L' Aquila (Italy); Incani, Angela; Mazzeo, Pietro; Ruggieri, Fabrizio [Dipartimento di Chimica, Ingegneria Chimica e Materiali, Universita degli Studi dell' Aquila, Via Vetoio, 67010 Coppito, L' Aquila (Italy)

2009-09-21

The adsorption of 25 symmetric triazines (s-triazines) on polybenzimidazole (PBI) beads is investigated under equilibrium (batch) conditions. The observed adsorption isotherms of the selected compounds are accurately described by the Freundlich model, while the agreement between the Langmuir model and the experimental data is moderately worse, which seems to reflect the heterogeneous meso- and micro-porosity of PBI and polydispersion in the interaction mechanism. Methylthio- and methoxytriazines exhibit a greater adsorption tendency as compared with chlorotriazines, moreover, progressive dealkylation of amino groups results in a progressive increase of triazine uptake on PBI. Based on these evidences, the adsorption mechanism seems to be governed by a combination of {pi}-{pi} and hydrogen-bonding interactions. Genetic algorithm (GA) variable selection and multilinear regression (MLR) are combined in order to describe the effect of triazine structure on the extraction performance of PBI according to the quantitative structure-property relationship (QSPR) method. q{sub max}, the amount of triazine adsorbed per weight unit of PBI assuming homogeneous monolayer (Langmuir) mechanism, exhibits a great variability within the set of investigated triazines and is the quantity here modelled by QSPR. On the other hand, the Freundlich constant, K{sub F}, which expresses the adsorption efficiency under multilayer heterogeneous conditions, even if markedly increases passing from chloro- to methylthio- or methoxytriazines, is less noticeably affected by the fine details of the adsorbate structure, as the number or nature of alkyl fragments bound to the amino groups. To quantitatively relate q{sub max} with the triazine structure GA-MLR analysis is performed on the set of 1664 theoretical molecular descriptors provided by the software Dragon. Finally, a four-dimensional QSPR model is selected based on leave-one-out cross-validation and its prediction ability is further tested on

Adsorption of s-triazines onto polybenzimidazole: A quantitative structure-property relationship investigation

International Nuclear Information System (INIS)

D'Archivio, Angelo Antonio; Incani, Angela; Mazzeo, Pietro; Ruggieri, Fabrizio

2009-01-01

The adsorption of 25 symmetric triazines (s-triazines) on polybenzimidazole (PBI) beads is investigated under equilibrium (batch) conditions. The observed adsorption isotherms of the selected compounds are accurately described by the Freundlich model, while the agreement between the Langmuir model and the experimental data is moderately worse, which seems to reflect the heterogeneous meso- and micro-porosity of PBI and polydispersion in the interaction mechanism. Methylthio- and methoxytriazines exhibit a greater adsorption tendency as compared with chlorotriazines, moreover, progressive dealkylation of amino groups results in a progressive increase of triazine uptake on PBI. Based on these evidences, the adsorption mechanism seems to be governed by a combination of π-π and hydrogen-bonding interactions. Genetic algorithm (GA) variable selection and multilinear regression (MLR) are combined in order to describe the effect of triazine structure on the extraction performance of PBI according to the quantitative structure-property relationship (QSPR) method. q max , the amount of triazine adsorbed per weight unit of PBI assuming homogeneous monolayer (Langmuir) mechanism, exhibits a great variability within the set of investigated triazines and is the quantity here modelled by QSPR. On the other hand, the Freundlich constant, K F , which expresses the adsorption efficiency under multilayer heterogeneous conditions, even if markedly increases passing from chloro- to methylthio- or methoxytriazines, is less noticeably affected by the fine details of the adsorbate structure, as the number or nature of alkyl fragments bound to the amino groups. To quantitatively relate q max with the triazine structure GA-MLR analysis is performed on the set of 1664 theoretical molecular descriptors provided by the software Dragon. Finally, a four-dimensional QSPR model is selected based on leave-one-out cross-validation and its prediction ability is further tested on four

Quantitative structure-property relationships of electroluminescent ...

Indian Academy of Sciences (India)

Thus, support vector machine is a good method to build QSPR models to predict the ... For high-quality OLED dis- ... it provides a guide to the development process and speeds up ... The free software ChemSketch 12.0 was used to draw 2-D.

QSPR Calculation of Normal Boiling Points of Organic Molecules Based on the Use of Correlation Weighting of Atomic Orbitals with Extended Connectivity of Zero- and First-Order Graphs of Atomic Orbitals

Directory of Open Access Journals (Sweden)

Eduardo A. Castro

2004-12-01

Full Text Available We report the results of a calculation of the normal boiling points of a representative set of 200 organic molecules through the application of QSPR theory. For this purpose we have used a particular set of flexible molecular descriptors, the so called Correlation Weighting of Atomic Orbitals with Extended Connectivity of Zero- and First-Order Graphs of Atomic Orbitals. Although in general the results show suitable behavior to predict this physical chemistry property, the existence of some deviant behaviors points to a need to complement this index with some other sort of molecular descriptors. Some possible extensions of this study are discussed.

A New Variable Selection Method Based on Mutual Information Maximization by Replacing Collinear Variables for Nonlinear Quantitative Structure-Property Relationship Models

Energy Technology Data Exchange (ETDEWEB)

Ghasemi, Jahan B.; Zolfonoun, Ehsan [Toosi University of Technology, Tehran (Korea, Republic of)

2012-05-15

Selection of the most informative molecular descriptors from the original data set is a key step for development of quantitative structure activity/property relationship models. Recently, mutual information (MI) has gained increasing attention in feature selection problems. This paper presents an effective mutual information-based feature selection approach, named mutual information maximization by replacing collinear variables (MIMRCV), for nonlinear quantitative structure-property relationship models. The proposed variable selection method was applied to three different QSPR datasets, soil degradation half-life of 47 organophosphorus pesticides, GC-MS retention times of 85 volatile organic compounds, and water-to-micellar cetyltrimethylammonium bromide partition coefficients of 62 organic compounds.The obtained results revealed that using MIMRCV as feature selection method improves the predictive quality of the developed models compared to conventional MI based variable selection algorithms.

A New Variable Selection Method Based on Mutual Information Maximization by Replacing Collinear Variables for Nonlinear Quantitative Structure-Property Relationship Models

International Nuclear Information System (INIS)

Ghasemi, Jahan B.; Zolfonoun, Ehsan

2012-01-01

Selection of the most informative molecular descriptors from the original data set is a key step for development of quantitative structure activity/property relationship models. Recently, mutual information (MI) has gained increasing attention in feature selection problems. This paper presents an effective mutual information-based feature selection approach, named mutual information maximization by replacing collinear variables (MIMRCV), for nonlinear quantitative structure-property relationship models. The proposed variable selection method was applied to three different QSPR datasets, soil degradation half-life of 47 organophosphorus pesticides, GC-MS retention times of 85 volatile organic compounds, and water-to-micellar cetyltrimethylammonium bromide partition coefficients of 62 organic compounds.The obtained results revealed that using MIMRCV as feature selection method improves the predictive quality of the developed models compared to conventional MI based variable selection algorithms

Molecular studies and plastic optical fiber device structures for nonlinear optical applications

Science.gov (United States)

Dirk, Carl W.; Nagarur, Aruna R.; Lu, Jin J.; Zhang, Lixia; Kalamegham, Priya; Fonseca, Joe; Gopalan, Saytha; Townsend, Scott; Gonzalez, Gabriel; Craig, Patrick; Rosales, Monica; Green, Leslie; Chan, Karen; Twieg, Robert J.; Ermer, Susan P.; Leung, Doris S.; Lovejoy, Steven M.; Lacroix, Suzanne; Godbout, Nicolas; Monette, Etienne

1995-10-01

Summarized are two project areas: First, the development of a quantitative structure property relationship for analyzing thermal decomposition differential scanning calorimetry data of electro-optic dyes is presented. The QSPR relationship suggest that thermal decomposition can be effectively correlated with structure by considering the kinds of atoms, their hybridization, and their nearest neighbor bonded atoms. Second, the simple preparation of clad plastic optical fibers (POF) is discussed with the intention of use for nonlinear optical applications. We discuss preparation techniques for single core and multiple core POF, and present some recent data on index profiles and the optimization of thermal stability in acrylate-based POF structures.

QUANTITATIVE ANALYSIS OF RELATIONSHIP STRUCTURE AND ANIONIC SURFACTANT MICELLE CONCENTRATION CRITIC WITH SEMIEMPIRIS AM1

Directory of Open Access Journals (Sweden)

Eva Vaulina Yulistia Delsy

2017-05-01

Full Text Available This research determines the mathematical equation which calculate the Concentration Micelle Critic theoretical anionic surfactant. The research was conducted the depiction of each surfactant anionic three-dimensional compound models, followed by optimizing the model structure anionic surfactant by using AM1 calculation method. Furthermore the calculation of descriptors (QSPR method, then it was analyzed statistically using Multiple Linear Regression (MLR. The results of statistical calculations showed that to calculate the theoretical CMC anionic surfactant can use the QSPR equation: log CMC = 4.157+0.118qC1+7.698qC2+0.425α–0.010µ-0.129RD–0.138 log P+0.021BM–0.034Avdw, n = 100 ; r = 0.927 ; r2 = 0.860 ; SE = 0.352 ; F= 30.888 ; PRESS = 23.506

Computational modeling of human oral bioavailability: what will be next?

Science.gov (United States)

Cabrera-Pérez, Miguel Ángel; Pham-The, Hai

2018-06-01

The oral route is the most convenient way of administrating drugs. Therefore, accurate determination of oral bioavailability is paramount during drug discovery and development. Quantitative structure-property relationship (QSPR), rule-of-thumb (RoT) and physiologically based-pharmacokinetic (PBPK) approaches are promising alternatives to the early oral bioavailability prediction. Areas covered: The authors give insight into the factors affecting bioavailability, the fundamental theoretical framework and the practical aspects of computational methods for predicting this property. They also give their perspectives on future computational models for estimating oral bioavailability. Expert opinion: Oral bioavailability is a multi-factorial pharmacokinetic property with its accurate prediction challenging. For RoT and QSPR modeling, the reliability of datasets, the significance of molecular descriptor families and the diversity of chemometric tools used are important factors that define model predictability and interpretability. Likewise, for PBPK modeling the integrity of the pharmacokinetic data, the number of input parameters, the complexity of statistical analysis and the software packages used are relevant factors in bioavailability prediction. Although these approaches have been utilized independently, the tendency to use hybrid QSPR-PBPK approaches together with the exploration of ensemble and deep-learning systems for QSPR modeling of oral bioavailability has opened new avenues for development promising tools for oral bioavailability prediction.

Quantitative structure–reactivity study on sulfonation of amines, alcohols and phenols

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Abolghasem Beheshti

2017-05-01

Full Text Available Quantitative structure–reactivity relationship (QSRR can be considered as a variant of quantitative structure property relationship (QSPR studies, where the chemical reactivity of reactants in a specified chemical reaction is related to chemical structure. As follows, the sulfonation reaction yield of 24 amines, alcohols and phenols with sulfonyl chloride was studied by QSRR. Quantum chemical calculations (b3lyp/6-31+g (d were carried out to obtain the optimized geometry. The suitable set of molecular descriptors was calculated to represent the molecular structures of compounds, such as constitutional, topological, geometrical, electrostatic and quantum-chemical descriptors. The genetic algorithm (GA was applied to select the variables that resulted in the best-fitted models. After the variable selection, multiple linear regression (MLR was utilized to construct linear QSRR models. The maximum relative error in prediction (5.26 showed that the predictive ability of the model was satisfactory and it can be used for designing similar reactants with efficient sulfonation reaction.

Rapid and Accurate Machine Learning Recognition of High Performing Metal Organic Frameworks for CO2 Capture.

Science.gov (United States)

Fernandez, Michael; Boyd, Peter G; Daff, Thomas D; Aghaji, Mohammad Zein; Woo, Tom K

2014-09-04

In this work, we have developed quantitative structure-property relationship (QSPR) models using advanced machine learning algorithms that can rapidly and accurately recognize high-performing metal organic framework (MOF) materials for CO2 capture. More specifically, QSPR classifiers have been developed that can, in a fraction of a section, identify candidate MOFs with enhanced CO2 adsorption capacity (>1 mmol/g at 0.15 bar and >4 mmol/g at 1 bar). The models were tested on a large set of 292 050 MOFs that were not part of the training set. The QSPR classifier could recover 945 of the top 1000 MOFs in the test set while flagging only 10% of the whole library for compute intensive screening. Thus, using the machine learning classifiers as part of a high-throughput screening protocol would result in an order of magnitude reduction in compute time and allow intractably large structure libraries and search spaces to be screened.

Predicting Complexation Thermodynamic Parameters of β-Cyclodextrin with Chiral Guests by Using Swarm Intelligence and Support Vector Machines

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Luckhana Lawtrakul

2009-05-01

Full Text Available The Particle Swarm Optimization (PSO and Support Vector Machines (SVMs approaches are used for predicting the thermodynamic parameters for the 1:1 inclusion complexation of chiral guests with β-cyclodextrin. A PSO is adopted for descriptor selection in the quantitative structure-property relationships (QSPR of a dataset of 74 chiral guests due to its simplicity, speed, and consistency. The modified PSO is then combined with SVMs for its good approximating properties, to generate a QSPR model with the selected features. Linear, polynomial, and Gaussian radial basis functions are used as kernels in SVMs. All models have demonstrated an impressive performance with R2 higher than 0.8.

Structure-retention and mobile phase-retention relationships for reversed-phase high-performance liquid chromatography of several hydroxythioxanthone derivatives in binary acetonitrile-water mixtures

International Nuclear Information System (INIS)

Amiri, Ali Asghar; Hemmateenejad, Bahram; Safavi, Afsaneh; Sharghi, Hashem; Beni, Ali Reza Salimi; Shamsipur, Mojtaba

2007-01-01

The reversed-phase high-performance liquid chromatographic (RP-HPLC) behavior of some newly synthesized hydroxythioxanthone derivatives using binary acetonitrile-water mixtures as mobile phase has been examined. First, the variation in the retention time of each molecule as a function of mobile phase properties was studied by Kamlet-Taft solvatochromic equations. Then, the influences of molecular structure of the hydroxythioxanthone derivatives on their retention time in various mobile phase mixtures were investigated by quantitative structure-property relationship (QSPR) analysis. Finally, a unified model containing both the molecular structure parameters and mobile phase properties was developed to describe the chromatographic behavior of the systems studied. Among the solvent properties, polarity/polarizability parameter (π * ) and hydrogen-bond basicity (β), and among the solute properties, the most positive local charge (MPC), the sum of positive charges on hydrogen atoms contributing in hydrogen bonding (SPCH) and lipophilicity index (log P) were identified as controlling factors in the RP-HPLC behavior of hydroxythioxanthone derivatives in actonitrile-water binary solvents

Models for risk assessment of reactive chemicals in aquatic toxicology

NARCIS (Netherlands)

Freidig, Andreas Peter

2000-01-01

A quantitative structure property relationship (QSPR) for a,b-unsaturated carboxylates (mainly acrylates and methacrylates) was established in chapter 2. Chemical reaction rate constants were measured for 12 different chemicals with three different nucleophiles, namely H 2 O, OH - and glutathione

A quantitative structure- property relationship of gas chromatographic/mass spectrometric retention data of 85 volatile organic compounds as air pollutant materials by multivariate methods

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Sarkhosh Maryam

2012-05-01

Full Text Available Abstract A quantitative structure-property relationship (QSPR study is suggested for the prediction of retention times of volatile organic compounds. Various kinds of molecular descriptors were calculated to represent the molecular structure of compounds. Modeling of retention times of these compounds as a function of the theoretically derived descriptors was established by multiple linear regression (MLR and artificial neural network (ANN. The stepwise regression was used for the selection of the variables which gives the best-fitted models. After variable selection ANN, MLR methods were used with leave-one-out cross validation for building the regression models. The prediction results are in very good agreement with the experimental values. MLR as the linear regression method shows good ability in the prediction of the retention times of the prediction set. This provided a new and effective method for predicting the chromatography retention index for the volatile organic compounds.

Development of Quantitative Structure-Property Relationship Models for Self-Emulsifying Drug Delivery System of 2-Aryl Propionic Acid NSAIDs

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Chen-Wen Li

2011-01-01

Full Text Available We developed the quantative structure-property relationships (QSPRs models to correlate the molecular structures of surfactant, cosurfactant, oil, and drug with the solubility of poorly water-soluble 2-aryl propionic acid nonsteroidal anti-inflammatory drugs (2-APA-NSAIDs in self-emulsifying drug delivery systems (SEDDSs. The compositions were encoded with electronic, geometrical, topological, and quantum chemical descriptors. To obtain reliable predictions, we used multiple linear regression (MLR and artificial neural network (ANN methods for model development. The obtained equations were validated using a test set of 42 formulations and showed a great predictive power, and linear models were found to be better than nonlinear ones. The obtained QSPR models would greatly facilitate fast screening for the optimal formulations of SEDDS at the early stage of drug development and minimize experimental effort.

Prediction of the Formulation Dependence of the Glass Transition Temperature for Amine-Epoxy Copolymers Using a Quantitative Structure-Property Relationship Based on the AM1 Method

National Research Council Canada - National Science Library

Morrill, Jason

2004-01-01

A designer Quantitative Structure-Property Relationsbip (QSPR) based upon molecular properties calculated using the AM1 semi-empirical quantum mechanical metbod was developed to predict the glass transition temperature (Tg...

Computational models for structure-hydrophobicity relationships of 4-carboxyl-2,6-dinitrophenyl azo hydroxynaphthalenes.

Science.gov (United States)

Idowu, Olakunle S; Adegoke, Olajire A; Idowu, Abiola; Olaniyi, Ajibola A

2007-01-01

Some phenyl azo hydroxynaphthalene dyes (e.g., sunset yellow) are certified as approved colorants for food, cosmetics, and drug formulations. The hydrophobicity of 4 newly synthesized azo dyes of the phenyl azo hydroxynaphthalene class was investigated, as a training set, with the goal of developing models for quantitative structure-property relationships (QSPR). Retention behavior of the molecules reversed-phase thin-layer chromatography (RPTLC) was investigated using liquid paraffin-coated silica gel as the stationary phase. Mobile phases consisted of aqueous mixtures of methanol, acetone, and dimethylformamide (DMF). Basic hydrophobicity parameter (Rmw), specific hydrophobic surface area (S), and isocratic chromatographic hydrophobicity index (phio) were computed from the chromatographic data. The hydrophobicity index (Rm) decreased linearly with increasing concentration of organic modifiers. Extrapolated Rmw values obtained by using DMF and acetone differ significantly from the value obtained by using methanol as organic modifier [P dyes and may also play useful roles in computer-assisted molecular discovery of nontoxic azo dyes.

Genetic algorithm as a variable selection procedure for the simulation of 13C nuclear magnetic resonance spectra of flavonoid derivatives using multiple linear regression.

Science.gov (United States)

Ghavami, Raoof; Najafi, Amir; Sajadi, Mohammad; Djannaty, Farhad

2008-09-01

In order to accurately simulate (13)C NMR spectra of hydroxy, polyhydroxy and methoxy substituted flavonoid a quantitative structure-property relationship (QSPR) model, relating atom-based calculated descriptors to (13)C NMR chemical shifts (ppm, TMS=0), is developed. A dataset consisting of 50 flavonoid derivatives was employed for the present analysis. A set of 417 topological, geometrical, and electronic descriptors representing various structural characteristics was calculated and separate multilinear QSPR models were developed between each carbon atom of flavonoid and the calculated descriptors. Genetic algorithm (GA) and multiple linear regression analysis (MLRA) were used to select the descriptors and to generate the correlation models. Analysis of the results revealed a correlation coefficient and root mean square error (RMSE) of 0.994 and 2.53ppm, respectively, for the prediction set.

Modeling the Dispersibility of Single Walled Carbon Nanotubes in Organic Solvents by Quantitative Structure-Activity Relationship Approach

Science.gov (United States)

Yilmaz, Hayriye; Rasulev, Bakhtiyor; Leszczynski, Jerzy

2015-01-01

The knowledge of physico-chemical properties of carbon nanotubes, including behavior in organic solvents is very important for design, manufacturing and utilizing of their counterparts with improved properties. In the present study a quantitative structure-activity/property relationship (QSAR/QSPR) approach was applied to predict the dispersibility of single walled carbon nanotubes (SWNTs) in various organic solvents. A number of additive descriptors and quantum-chemical descriptors were calculated and utilized to build QSAR models. The best predictability is shown by a 4-variable model. The model showed statistically good results (R2training = 0.797, Q2 = 0.665, R2test = 0.807), with high internal and external correlation coefficients. Presence of the X0Av descriptor and its negative term suggest that small size solvents have better SWCNTs solubility. Mass weighted descriptor ATS6m also indicates that heavier solvents (and small in size) most probably are better solvents for SWCNTs. The presence of the Dipole Z descriptor indicates that higher polarizability of the solvent molecule increases the solubility. The developed model and contributed descriptors can help to understand the mechanism of the dispersion process and predictorganic solvents that improve the dispersibility of SWNTs. PMID:28347035

Modeling the Dispersibility of Single Walled Carbon Nanotubes in Organic Solvents by Quantitative Structure-Activity Relationship Approach

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Hayriye Yilmaz

2015-05-01

Full Text Available The knowledge of physico-chemical properties of carbon nanotubes, including behavior in organic solvents is very important for design, manufacturing and utilizing of their counterparts with improved properties. In the present study a quantitative structure-activity/property relationship (QSAR/QSPR approach was applied to predict the dispersibility of single walled carbon nanotubes (SWNTs in various organic solvents. A number of additive descriptors and quantum-chemical descriptors were calculated and utilized to build QSAR models. The best predictability is shown by a 4-variable model. The model showed statistically good results (R2training = 0.797, Q2 = 0.665, R2test = 0.807, with high internal and external correlation coefficients. Presence of the X0Av descriptor and its negative term suggest that small size solvents have better SWCNTs solubility. Mass weighted descriptor ATS6m also indicates that heavier solvents (and small in size most probably are better solvents for SWCNTs. The presence of the Dipole Z descriptor indicates that higher polarizability of the solvent molecule increases the solubility. The developed model and contributed descriptors can help to understand the mechanism of the dispersion process and predictorganic solvents that improve the dispersibility of SWNTs.

Using Combined Computational Techniques to Predict the Glass Transition Temperatures of Aromatic Polybenzoxazines

Science.gov (United States)

Mhlanga, Phumzile; Wan Hassan, Wan Aminah; Hamerton, Ian; Howlin, Brendan J.

2013-01-01

The Molecular Operating Environment software (MOE) is used to construct a series of benzoxazine monomers for which a variety of parameters relating to the structures (e.g. water accessible surface area, negative van der Waals surface area, hydrophobic volume and the sum of atomic polarizabilities, etc.) are obtained and quantitative structure property relationships (QSPR) models are formulated. Three QSPR models (formulated using up to 5 descriptors) are first used to make predictions for the initiator data set (n = 9) and compared to published thermal data; in all of the QSPR models there is a high level of agreement between the actual data and the predicted data (within 0.63–1.86 K of the entire dataset). The water accessible surface area is found to be the most important descriptor in the prediction of Tg. Molecular modelling simulations of the benzoxazine polymer (minus initiator) carried out at the same time using the Materials Studio software suite provide an independent prediction of Tg. Predicted Tg values from molecular modelling fall in the middle of the range of the experimentally determined Tg values, indicating that the structure of the network is influenced by the nature of the initiator used. Hence both techniques can provide predictions of glass transition temperatures and provide complementary data for polymer design. PMID:23326419

Using combined computational techniques to predict the glass transition temperatures of aromatic polybenzoxazines.

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Phumzile Mhlanga

Full Text Available The Molecular Operating Environment software (MOE is used to construct a series of benzoxazine monomers for which a variety of parameters relating to the structures (e.g. water accessible surface area, negative van der Waals surface area, hydrophobic volume and the sum of atomic polarizabilities, etc. are obtained and quantitative structure property relationships (QSPR models are formulated. Three QSPR models (formulated using up to 5 descriptors are first used to make predictions for the initiator data set (n = 9 and compared to published thermal data; in all of the QSPR models there is a high level of agreement between the actual data and the predicted data (within 0.63-1.86 K of the entire dataset. The water accessible surface area is found to be the most important descriptor in the prediction of T(g. Molecular modelling simulations of the benzoxazine polymer (minus initiator carried out at the same time using the Materials Studio software suite provide an independent prediction of T(g. Predicted T(g values from molecular modelling fall in the middle of the range of the experimentally determined T(g values, indicating that the structure of the network is influenced by the nature of the initiator used. Hence both techniques can provide predictions of glass transition temperatures and provide complementary data for polymer design.

Predicting water solubility of congeners: Chloronaphthalenes-A case study

Energy Technology Data Exchange (ETDEWEB)

Puzyn, Tomasz, E-mail: puzi@qsar.eu.org [Faculty of Chemistry, University of Gdansk, Sobieskiego 18, 80-952 Gdansk (Poland); Mostrag, Aleksandra; Falandysz, Jerzy [Faculty of Chemistry, University of Gdansk, Sobieskiego 18, 80-952 Gdansk (Poland); Kholod, Yana; Leszczynski, Jerzy [NSF CREST Nanotoxicity Center, Department of Chemistry, Jackson State University, 1325 Lynch St, Jackson, MS 39217-0510 (United States)

2009-10-30

Since the important physicochemical data for chloronaphtalenes (PCNs) are still scarce, we have predicted water solubility (log S) of all 75 congeners with the Quantitative Structure-Property Relationship (QSPR) scheme. The values of log S, predicted by the most efficient model, varied from 0.01 to 1660 {mu}g dm{sup -3} (2.85 x 10{sup -11}-1.02 x 10{sup -5} mol dm{sup -3}), depending on the number of chlorine atoms present in the molecule and the substitution pattern. We found that the main factor determining relative differences in solubility between the congeners is the solvent accessible volume related to the cavitation process occurring in the solvent. The results are presented as a case study of QSPR modeling for those Persistent Organic Pollutants (POPs) that exist as families of congeners. By investigating the impact of (i) the way of the molecular descriptors' calculation, (ii) the size of applied database and (iii) chemometric method of modeling (Multiple Linear Regression, MLR, and/or Partial Least Squares regression, PLS) on the quality of the models we proposed general recommendations for dealing with congeners. We found that the combination of the B3LYP functional with 6-311++G(d,p) basis set was the most optimal technique of the molecular descriptors' calculation for congeners when comparing with semi-empirical PM3, ab initio Hartee-Fock (HF), and Moller-Pleset 2 (MP2) method carried out with different-size basis sets. Moreover, the model developed with a larger and more general database that includes chloronaphthalenes, polychlorinated dibezno-p-dioxins, furans and biphenyls predicted the values of log S for PCNs noticeable worse than the model calibrated only on PCNs. In the later case it was possible to obtain satisfactory results by employing even the simplest MLR method and only one molecular descriptor. The values of log S were also calculated with the WSKOWIN and COSMO-RS models as the reference techniques and then compared to our

Predicting water solubility of congeners: Chloronaphthalenes-A case study

International Nuclear Information System (INIS)

Puzyn, Tomasz; Mostrag, Aleksandra; Falandysz, Jerzy; Kholod, Yana; Leszczynski, Jerzy

2009-01-01

Since the important physicochemical data for chloronaphtalenes (PCNs) are still scarce, we have predicted water solubility (log S) of all 75 congeners with the Quantitative Structure-Property Relationship (QSPR) scheme. The values of log S, predicted by the most efficient model, varied from 0.01 to 1660 μg dm -3 (2.85 x 10 -11 -1.02 x 10 -5 mol dm -3 ), depending on the number of chlorine atoms present in the molecule and the substitution pattern. We found that the main factor determining relative differences in solubility between the congeners is the solvent accessible volume related to the cavitation process occurring in the solvent. The results are presented as a case study of QSPR modeling for those Persistent Organic Pollutants (POPs) that exist as families of congeners. By investigating the impact of (i) the way of the molecular descriptors' calculation, (ii) the size of applied database and (iii) chemometric method of modeling (Multiple Linear Regression, MLR, and/or Partial Least Squares regression, PLS) on the quality of the models we proposed general recommendations for dealing with congeners. We found that the combination of the B3LYP functional with 6-311++G(d,p) basis set was the most optimal technique of the molecular descriptors' calculation for congeners when comparing with semi-empirical PM3, ab initio Hartee-Fock (HF), and Moller-Pleset 2 (MP2) method carried out with different-size basis sets. Moreover, the model developed with a larger and more general database that includes chloronaphthalenes, polychlorinated dibezno-p-dioxins, furans and biphenyls predicted the values of log S for PCNs noticeable worse than the model calibrated only on PCNs. In the later case it was possible to obtain satisfactory results by employing even the simplest MLR method and only one molecular descriptor. The values of log S were also calculated with the WSKOWIN and COSMO-RS models as the reference techniques and then compared to our results.

CALCULATION OF COEFFICIENT OF SHARING OCTANOL-WATER OF ORGANIC COMPOUNDS USING MOLECULAR DESCRIPTORS

Directory of Open Access Journals (Sweden)

B. Souyei

2010-12-01

Full Text Available A quantitative structure-property relationship (QSPR study is carried out to develop correlations that relate the molecular structures of organic compounds to their Octanol- Water partition coefficients, Kow , using molecular descriptors. The correlations are simple in application with good accuracy, which provide an easy, direct and relatively accurate way to calculate Kow. Such calculation gives us a model that gives results in remarkable correlation with the descriptors of blocks fragments of the atom-centered and functional groups (R2 = 0.949, δ = 0477 (R2 = 0.926,δ = 0,548 respectively.

Brand relationships: A study of five relationship constructs

DEFF Research Database (Denmark)

Bergkvist, Lars; Bech-Larsen, Tino

This study investigates the relationships between the five brand relationship constructs sense of community, brand identification, brand love, brand loyalty, and active engagement. Structural equation modelling with partial least squares showed provided support for six relational hypotheses...

Developing descriptors to predict mechanical properties of nanotubes.

Science.gov (United States)

Borders, Tammie L; Fonseca, Alexandre F; Zhang, Hengji; Cho, Kyeongjae; Rusinko, Andrew

2013-04-22

Descriptors and quantitative structure property relationships (QSPR) were investigated for mechanical property prediction of carbon nanotubes (CNTs). 78 molecular dynamics (MD) simulations were carried out, and 20 descriptors were calculated to build quantitative structure property relationships (QSPRs) for Young's modulus and Poisson's ratio in two separate analyses: vacancy only and vacancy plus methyl functionalization. In the first analysis, C(N2)/C(T) (number of non-sp2 hybridized carbons per the total carbons) and chiral angle were identified as critical descriptors for both Young's modulus and Poisson's ratio. Further analysis and literature findings indicate the effect of chiral angle is negligible at larger CNT radii for both properties. Raman spectroscopy can be used to measure C(N2)/C(T), providing a direct link between experimental and computational results. Poisson's ratio approaches two different limiting values as CNT radii increases: 0.23-0.25 for chiral and armchair CNTs and 0.10 for zigzag CNTs (surface defects <3%). In the second analysis, the critical descriptors were C(N2)/C(T), chiral angle, and M(N)/C(T) (number of methyl groups per total carbons). These results imply new types of defects can be represented as a new descriptor in QSPR models. Finally, results are qualified and quantified against experimental data.

Adsorption of dyes onto activated carbon cloth: using QSPRs as tools to approach adsorption mechanisms.

Science.gov (United States)

Metivier-Pignon, Hélène; Faur, Catherine; Le Cloirec, Pierre

2007-01-01

The present study aimed to investigate the adsorption of dyes onto activated carbon cloths. Kinetics and isotherms were studied based on results of batch reactors to constitute databases for the adsorption rates and capacities of 22 commercial dyes. Added to a qualitative analysis of experimental results, quantitative structure property relationships (QSPRs) were used to determine the structural features that influence most adsorption processes. QSPRs consisted of multiple linear regressions correlating adsorption parameters with molecular connectivity indices (MCIs) as molecular descriptors. Results related to adsorption kinetics showed that the size of molecules was the significant feature, the high order MCIs involved in QSPRs indicating the influence of a critical size on adsorption rate. Improved statistical fits were obtained when the database was divided according to the chemical classes of dyes. As regards to adsorption isotherms, their particular form led to the use of saturation capacity as the adsorption parameter. By contrast with adsorption kinetics, molecular overcrowding seemed to be of less influence on adsorption equilibrium. In this case, MCIs included in the QSPR were more related to details of the molecular structure. The robustness of the QSPR assessed for azo dyes was studied for the other dyes. Although the small size of the database limited predictive ability, features relevant to the influence of the database composition on QSPRs have been highlighted.

Filling the gap: Estimating physicochemical properties of the full array of polybrominated diphenyl ethers (PBDEs)

International Nuclear Information System (INIS)

Yue, Chaoyang; Li, Loretta Y.

2013-01-01

Physicochemical properties of PBDE congeners are important for modeling their transport, but data are often missing. The quantitative structure–property relationship (QSPR) approach is utilized to fill this gap. Individual research groups often report piecemeal properties through experimental measurements or estimation techniques, but these data seldom satisfy fundamental thermodynamic relationships because of errors. The data then lack internal consistency and cannot be used directly in environmental modeling. This paper critically reviews published experimental data to select the best QSPR models, which are then extended to all 209 PBDE congeners. Properties include aqueous solubility, vapor pressure, Henry's law constant, octanol–water partition coefficient and octanol–air partition coefficient. Their values are next adjusted to satisfy fundamental thermodynamic equations. The resulting values then take advantage of all measurements and provide quick references for modeling and PBDE-contaminated site assessment and remediation. PCBs are also compared with respect to their properties and estimation methods. -- Highlights: •Property data of PBDEs and reported experimental and estimation methods were reviewed. •Missing data were estimated for all 209 PBDEs based on selected methods. •All data were adjusted to meet thermodynamic constrains using a VisualBasic program. •The established database provides a quick reference for PBDE environmental modeling. -- Through careful selection of literature data, structure–property estimation and adjustment, key properties of 209 PBDE congeners are estimated with internal consistency

Towards the Development of Global Nano-Quantitative Structure–Property Relationship Models: Zeta Potentials of Metal Oxide Nanoparticles

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Andrey A. Toropov

2018-04-01

Full Text Available Zeta potential indirectly reflects a charge of the surface of nanoparticles in solutions and could be used to represent the stability of the colloidal solution. As processes of synthesis, testing and evaluation of new nanomaterials are expensive and time-consuming, so it would be helpful to estimate an approximate range of properties for untested nanomaterials using computational modeling. We collected the largest dataset of zeta potential measurements of bare metal oxide nanoparticles in water (87 data points. The dataset was used to develop quantitative structure–property relationship (QSPR models. Essential features of nanoparticles were represented using a modified simplified molecular input line entry system (SMILES. SMILES strings reflected the size-dependent behavior of zeta potentials, as the considered quasi-SMILES modification included information about both chemical composition and the size of the nanoparticles. Three mathematical models were generated using the Monte Carlo method, and their statistical quality was evaluated (R2 for the training set varied from 0.71 to 0.87; for the validation set, from 0.67 to 0.82; root mean square errors for both training and validation sets ranged from 11.3 to 17.2 mV. The developed models were analyzed and linked to aggregation effects in aqueous solutions.

Relationship Structure, Relationship Texture: Case Studies in Non/Monogamies Research

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Jessica Joan Kean

2017-05-01

Full Text Available This article develops case studies from qualitative interviews with people in negotiated non-monogamous relationships to ask what discursive or practical factors besides non/monogamy might play a role in assessments of a relationship’s structure or worth. Beginning with an auto-ethnographic reflection on the way the ‘significance’ was recognised and misrecognised in one polyamorous ‘thrupple’, I introduce three case studies of people in negotiated non-monogamous relationships in order to bring a cultural studies method of the particular to the study of intimacy. For the individuals in these case studies, the practice and experience of non/monogamy is inextricably linked to the ideas and practices surrounding gender, sexuality, sex work, friendship, HIV status and ability. Sketching a middle path between the romantic’s dream of love as a state of exception or exemption from the social and the theorist’s map of the patterned effects of hetero- and mono-normativities, this article attends to the contingency, flexibility and incoherence which so often underpins the sense we make of relationships, even as that sense is shaped by the practices, ideals and institutions of intimacy, love and friendship.

Bond-based linear indices of the non-stochastic and stochastic edge-adjacency matrix. 1. Theory and modeling of ChemPhys properties of organic molecules.

Science.gov (United States)

Marrero-Ponce, Yovani; Martínez-Albelo, Eugenio R; Casañola-Martín, Gerardo M; Castillo-Garit, Juan A; Echevería-Díaz, Yunaimy; Zaldivar, Vicente Romero; Tygat, Jan; Borges, José E Rodriguez; García-Domenech, Ramón; Torrens, Francisco; Pérez-Giménez, Facundo

2010-11-01

Novel bond-level molecular descriptors are proposed, based on linear maps similar to the ones defined in algebra theory. The kth edge-adjacency matrix (E(k)) denotes the matrix of bond linear indices (non-stochastic) with regard to canonical basis set. The kth stochastic edge-adjacency matrix, ES(k), is here proposed as a new molecular representation easily calculated from E(k). Then, the kth stochastic bond linear indices are calculated using ES(k) as operators of linear transformations. In both cases, the bond-type formalism is developed. The kth non-stochastic and stochastic total linear indices are calculated by adding the kth non-stochastic and stochastic bond linear indices, respectively, of all bonds in molecule. First, the new bond-based molecular descriptors (MDs) are tested for suitability, for the QSPRs, by analyzing regressions of novel indices for selected physicochemical properties of octane isomers (first round). General performance of the new descriptors in this QSPR studies is evaluated with regard to the well-known sets of 2D/3D MDs. From the analysis, we can conclude that the non-stochastic and stochastic bond-based linear indices have an overall good modeling capability proving their usefulness in QSPR studies. Later, the novel bond-level MDs are also used for the description and prediction of the boiling point of 28 alkyl-alcohols (second round), and to the modeling of the specific rate constant (log k), partition coefficient (log P), as well as the antibacterial activity of 34 derivatives of 2-furylethylenes (third round). The comparison with other approaches (edge- and vertices-based connectivity indices, total and local spectral moments, and quantum chemical descriptors as well as E-state/biomolecular encounter parameters) exposes a good behavior of our method in this QSPR studies. Finally, the approach described in this study appears to be a very promising structural invariant, useful not only for QSPR studies but also for similarity

ADME evaluation in drug discovery. 1. Applications of genetic algorithms to the prediction of blood-brain partitioning of a large set of drugs.

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Hou, Tingjun; Xu, Xiaojie

2002-12-01

In this study, the relationships between the brain-blood concentration ratio of 96 structurally diverse compounds with a large number of structurally derived descriptors were investigated. The linear models were based on molecular descriptors that can be calculated for any compound simply from a knowledge of its molecular structure. The linear correlation coefficients of the models were optimized by genetic algorithms (GAs), and the descriptors used in the linear models were automatically selected from 27 structurally derived descriptors. The GA optimizations resulted in a group of linear models with three or four molecular descriptors with good statistical significance. The change of descriptor use as the evolution proceeds demonstrates that the octane/water partition coefficient and the partial negative solvent-accessible surface area multiplied by the negative charge are crucial to brain-blood barrier permeability. Moreover, we found that the predictions using multiple QSPR models from GA optimization gave quite good results in spite of the diversity of structures, which was better than the predictions using the best single model. The predictions for the two external sets with 37 diverse compounds using multiple QSPR models indicate that the best linear models with four descriptors are sufficiently effective for predictive use. Considering the ease of computation of the descriptors, the linear models may be used as general utilities to screen the blood-brain barrier partitioning of drugs in a high-throughput fashion.

A primer on QSAR/QSPR modeling fundamental concepts

CERN Document Server

Roy, Kunal; Das, Rudra Narayan

2015-01-01

This brief goes back to basics and describes the Quantitative structure-activity/property relationships (QSARs/QSPRs) that represent predictive models derived from the application of statistical tools correlating biological activity (including therapeutic and toxic) and properties of chemicals (drugs/toxicants/environmental pollutants) with descriptors representative of molecular structure and/or properties. It explains how the sub-discipline of Cheminformatics is used for many applications such as risk assessment, toxicity prediction, property prediction and regulatory decisions apart from drug discovery and lead optimization. The authors also present, in basic terms, how QSARs and related chemometric tools are extensively involved in medicinal chemistry, environmental chemistry and agricultural chemistry for ranking of potential compounds and prioritizing experiments. At present, there is no standard or introductory publication available that introduces this important topic to students of chemistry and phar...

The application of feature selection to the development of Gaussian process models for percutaneous absorption.

Science.gov (United States)

Lam, Lun Tak; Sun, Yi; Davey, Neil; Adams, Rod; Prapopoulou, Maria; Brown, Marc B; Moss, Gary P

2010-06-01

The aim was to employ Gaussian processes to assess mathematically the nature of a skin permeability dataset and to employ these methods, particularly feature selection, to determine the key physicochemical descriptors which exert the most significant influence on percutaneous absorption, and to compare such models with established existing models. Gaussian processes, including automatic relevance detection (GPRARD) methods, were employed to develop models of percutaneous absorption that identified key physicochemical descriptors of percutaneous absorption. Using MatLab software, the statistical performance of these models was compared with single linear networks (SLN) and quantitative structure-permeability relationships (QSPRs). Feature selection methods were used to examine in more detail the physicochemical parameters used in this study. A range of statistical measures to determine model quality were used. The inherently nonlinear nature of the skin data set was confirmed. The Gaussian process regression (GPR) methods yielded predictive models that offered statistically significant improvements over SLN and QSPR models with regard to predictivity (where the rank order was: GPR > SLN > QSPR). Feature selection analysis determined that the best GPR models were those that contained log P, melting point and the number of hydrogen bond donor groups as significant descriptors. Further statistical analysis also found that great synergy existed between certain parameters. It suggested that a number of the descriptors employed were effectively interchangeable, thus questioning the use of models where discrete variables are output, usually in the form of an equation. The use of a nonlinear GPR method produced models with significantly improved predictivity, compared with SLN or QSPR models. Feature selection methods were able to provide important mechanistic information. However, it was also shown that significant synergy existed between certain parameters, and as such it

Shared Relationship Efficacy of Dyad Can Increase Life Satisfaction in Close Relationships: Multilevel Study

Science.gov (United States)

Ito, Kenichi; Yoshida, Toshikazu

2016-01-01

Characteristics of relationship itself play an important role in determining well-being of individuals who participate in the relationship. We used efficacy expectations mutually shared between close friends or romantic partners as a characteristic of relationship and investigated its impact on their life satisfaction. In Study 1, we conducted a cross-sectional study among 137 pairs of close same-sex friends to test whether the efficacy expectations shared between friends are associated with levels of life satisfaction. In Study 2, we conducted a longitudinal study among 114 heterosexual romantic couples to test predictive validity of the efficacy expectations shared between couples predict levels of life satisfaction 2 month later. In both studies we found a consistent result that as degrees of the efficacy expectations shared between individuals in a relationship increased, the degree of their life satisfaction also increased. Underlying mechanisms that explain how characteristics of relationship itself increase life satisfaction are discussed. PMID:27437946

Quantitative structure--property relationships for enhancing predictions of synthetic organic chemical removal from drinking water by granular activated carbon.

Science.gov (United States)

Magnuson, Matthew L; Speth, Thomas F

2005-10-01

Granular activated carbon is a frequently explored technology for removing synthetic organic contaminants from drinking water sources. The success of this technology relies on a number of factors based not only on the adsorptive properties of the contaminant but also on properties of the water itself, notably the presence of substances in the water which compete for adsorption sites. Because it is impractical to perform field-scale evaluations for all possible contaminants, the pore surface diffusion model (PSDM) has been developed and used to predict activated carbon column performance using single-solute isotherm data as inputs. Many assumptions are built into this model to account for kinetics of adsorption and competition for adsorption sites. This work further evaluates and expands this model, through the use of quantitative structure-property relationships (QSPRs) to predict the effect of natural organic matter fouling on activated carbon adsorption of specific contaminants. The QSPRs developed are based on a combination of calculated topographical indices and quantum chemical parameters. The QSPRs were evaluated in terms of their statistical predictive ability,the physical significance of the descriptors, and by comparison with field data. The QSPR-enhanced PSDM was judged to give results better than what could previously be obtained.

Relationship intention amongst clothing retail customers: An exploratory study

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Stefanie W. Kuhn

2015-08-01

Full Text Available Orientation: Increasing competition has resulted in clothing retailers placing more emphasis on expensive relationship marketing tactics to retain customers. The retailers often use customers’ loyalty programme membership and the duration of their support to identify and target them in relationship-building efforts. Research purpose: This study determines the viability of relationship intention by measuring and categorising clothing customers according to their relationship intentions. The study also explores the duration of customer support for a clothing retailer, membership of their loyalty programme and the relationship thereof with customers’ relationship intentions towards that retailer. Motivation for the study: Relationship building efforts would be better directed at customers with relationship intentions. Research design, approach and method: Quantitative in nature, this study followed a descriptive research design and used an interviewer-administered survey to collect data from 511 clothing retail customers residing in the greater Pretoria metropolitan area. Main findings: Clothing retailers can effectively determine and categorise customers according to their relationship intentions. The duration customers have supported a clothing retailer and its loyalty programme has no relationship with their relationship intentions. Practical/Managerial implications: Clothing retailers should focus their relationship building on customers with relationship intentions, as they are more likely to respond favourably. They are more likely to be retained by the clothing retailer and provide a return on investment. Contribution/value-add: This study gives clothing retailers a reliable and valid measuring instrument that can be used to identify customers with relationship intentions, rather than relying on the duration of the customers’ support and their loyalty programme membership.

Cheminformatics Modeling of Amine Solutions for Assessing their CO2 Absorption Properties.

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Kuenemann, Melaine A; Fourches, Denis

2017-07-01

As stricter regulations on CO 2 emissions are adopted worldwide, identifying efficient chemical processes to capture and recycle CO 2 is of critical importance for industry. The most common process known as amine scrubbing suffers from the lack of available amine solutions capable of capturing CO 2 efficiently. Tertiary amines characterized by low heats of reaction are considered good candidates but their absorption properties can significantly differ from one analogue to another despite high structural similarity. Herein, after collecting and curating experimental data from the literature, we have built a modeling set of 41 amine structures with their absorption properties. Then we analyzed their chemical composition using molecular descriptors and non-supervised clustering. Furthermore, we developed a series of quantitative structure-property relationships (QSPR) to assess amines' CO 2 absorption properties from their structural characteristics. These models afforded reasonable prediction performances (e. g., Q 2 LOO =0.63 for CO 2 absorption amount) even though they are solely based on 2D chemical descriptors and individual machine learning techniques (random forest and neural network). Overall, we believe the chemical analysis and the series of QSPR models presented in this proof-of-concept study represent new knowledge and innovative tools that could be very useful for screening and prioritizing hypothetical amines to be synthesized and tested experimentally for their CO 2 absorption properties. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Parent-child relationships, partner relationships, and emotional adjustment: a birth-to-maturity prospective study.

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Overbeek, Geertjan; Stattin, Håkan; Vermulst, Ad; Ha, Thao; Engels, Rutger C M E

2007-03-01

This study examined whether detrimental childhood relationships with parents were related to partner relationship quality and emotional adjustment in adulthood. The authors tested a theoretical model in which (a) low-quality parent-child relationships were related to conflict and low-quality communication with parents in adolescence, (b) parent-adolescent conflict and low-quality communication were linked to low-quality partner relationships in young adulthood, and (c) low-quality partner relationships in young adulthood were predictive of low-quality partner relationships as well as depression, anxiety, and dissatisfaction with life at midlife. Multi-informant data were used from 212 Swedish individuals who were followed from birth into adulthood. Results demonstrated that, as hypothesized, negative parent-child bonds were indirectly related to low-quality partner relationships and dissatisfaction with life in adulthood (but not anxiety and depression) through conflictual parent-adolescent communication and low-quality partner relationships in young adulthood.

Artificial evolution of coumarin dyes for dye sensitized solar cells.

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Venkatraman, Vishwesh; Abburu, Sailesh; Alsberg, Bjørn Kåre

2015-11-07

The design and discovery of novel molecular structures with optimal properties has been an ongoing effort for materials scientists. This field has in general been dominated by experiment driven trial-and-error approaches that are often expensive and time-consuming. Here, we investigate if a de novo computational design methodology can be applied to the design of coumarin-based dye sensitizers with improved properties for use in Grätzel solar cells. To address the issue of synthetic accessibility of the designed compounds, a fragment-based assembly is employed, wherein the combination of chemical motifs (derived from the existing databases of structures) is carried out with respect to user-adaptable set of rules. Rather than using computationally intensive density functional theory (DFT)/ab initio methods to screen candidate dyes, we employ quantitative structure-property relationship (QSPR) models (calibrated from empirical data) for rapid estimation of the property of interest, which in this case is the product of short circuit current (Jsc) and open circuit voltage (Voc). Since QSPR models have limited validity, pre-determined applicability domain criteria are used to prevent unacceptable extrapolation. DFT analysis of the top-ranked structures provides supporting evidence of their potential for dye sensitized solar cell applications.

A framework for studying relationship marketing dyads

NARCIS (Netherlands)

Lindgreen, A.

2001-01-01

Although coined more than 15 years ago, relationship marketing remains an ambiguous concept with plenty of rhetoric but few publications on empirical evidence in support of a relationship marketing paradigm shift. A research project is currently studying marketing dyads in the international food

Relationship dissatisfaction and other risk factors for future relationship dissolution: a population-based study of 18,523 couples.

Science.gov (United States)

Røsand, Gun-Mette B; Slinning, Kari; Røysamb, Espen; Tambs, Kristian

2014-01-01

There has been a marked increase in divorce rates in most Western societies over the last 50 years. Relationship dissolution is associated with negative consequences both for adults and children, so it is important to understand the factors that help retain marital stability. The first aim of this prospective study was to identify risk factors for relationship dissolution in 18,523 couples in Norway, with a particular focus on individual dissatisfaction with the relationship. The second aim was to assess interaction effects between relationship dissatisfaction and other predictors of relationship dissolution. Pregnant women and their partners enrolled in the Norwegian Mother and Child Cohort study completed questionnaires during the pregnancy that asked about relationship dissatisfaction, strain, demographics, and other risk factors. The main outcome variable was relationship dissolution in the 39-month period from gestational week 30-36 months postpartum. Associations between the risk factors and relationship dissolution were estimated by logistic regression analysis. Except for younger female age, relationship dissatisfaction in women and lower education in men, were the strongest predictors of relationship dissolution. Another strong factor was women's persistent strain. No significant interaction effects were found between relationship dissatisfaction and the other variables in the analyses. Dissatisfaction with the relationship, in particular in women, and low male education are important predictors of relationship dissolution, although other factors are also related to dissolution. There are only few studies on relationship predictors of dissolution conducted in Europe, and the current study adds to this body of knowledge.

Predicción del volumen molar y la entalpía molar de vaporización de moléculas orgánicas usando variables determinadas mediante el modelo de apantallamiento tipo conductor (COSMO

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José G. Parra

2011-12-01

Full Text Available Using the method of solvation Conductor-like Screening Model (COSMO and the method of Amovilli-Menucci GAMESS program content, we estimated the free energies of van der Waals and electrostatic of organic molecules in their dielectric medium. With these energy and volume of the solute cavity, we designed two models of structure-property relationship (QSPR to determine the molar volume and enthalpy of vaporization to the ebullition temperature of organic molecules. The best obtained model using the molecular volume presents a correlation equal to 0.9949 and the correlation of the model using the enthalpy of vaporization was 0. 9895.

Probabilistic relationships in acceptable risk studies

International Nuclear Information System (INIS)

Benjamin, J.R.

1977-01-01

Acceptable risk studies involve uncertainties in future events; consequences and associated values, the acceptability levels, and the future decision environment. Probabilistic procedures afford the basic analytical tool to study the influence of each of these parameters on the acceptable risk decision, including their interrelationships, and combinations. A series of examples are presented in the paper in increasing complexity to illustrate the principles involved and to quantify the relationships to the acceptable risk decision. The basic objective of such studies is to broaden the scientific basis of acceptable risk decision making. It is shown that rationality and consistency in decision making is facilitated by such studies and that rather simple relationships exist in many situations of interest. The variation in criteria associated with an increase in the state of knowledge or change in the level of acceptability is also discussed. (Auth.)

Probabilistic relationships in acceptable risk studies

International Nuclear Information System (INIS)

Benjamin, J.R.

1977-01-01

Acceptable risk studies involve uncertainties in future events: consequences and associated values, the acceptability levels, and the future decision environment. Probabilistic procedures afford the basic analytical tool to study the influence of each of these parameters on the acceptable risk decision, including their interrelationships, and combinations. A series of examples are presented in the paper in increasing complexity to illustrate the principles involved and to quantify the relationships to the acceptable risk decision. The basic objective of such studies is to broaden the scientific basis of acceptable risk decision making. It is shown that rationality and consistency in decision making is facilitated by such studies and that rather simple relationships exist in many situations of interest. The variation in criteria associated with an increase in the state of knowledge or change in the level of acceptability is also discussed

Prediction of toxicity of nitrobenzenes using ab initio and least squares support vector machines

International Nuclear Information System (INIS)

Niazi, Ali; Jameh-Bozorghi, Saeed; Nori-Shargh, Davood

2008-01-01

A quantitative structure-property relationship (QSPR) study is suggested for the prediction of toxicity (IGC 50 ) of nitrobenzenes. Ab initio theory was used to calculate some quantum chemical descriptors including electrostatic potentials and local charges at each atom, HOMO and LUMO energies, etc. Modeling of the IGC 50 of nitrobenzenes as a function of molecular structures was established by means of the least squares support vector machines (LS-SVM). This model was applied for the prediction of the toxicity (IGC 50 ) of nitrobenzenes, which were not in the modeling procedure. The resulted model showed high prediction ability with root mean square error of prediction of 0.0049 for LS-SVM. Results have shown that the introduction of LS-SVM for quantum chemical descriptors drastically enhances the ability of prediction in QSAR studies superior to multiple linear regression and partial least squares

Derivatives in discrete mathematics: a novel graph-theoretical invariant for generating new 2/3D molecular descriptors. I. Theory and QSPR application.

Science.gov (United States)

Marrero-Ponce, Yovani; Santiago, Oscar Martínez; López, Yoan Martínez; Barigye, Stephen J; Torrens, Francisco

2012-11-01

among different atoms, an atomic weighting scheme (atom-type labels) is used in the formation of the matrix Q or in LOVIs state. The obtained indices were utilized to describe the partition coefficient (Log P) and the reactivity index (Log K) of the 34 derivatives of 2-furylethylenes. In all the cases, our MDs showed better statistical results than those previously obtained using some of the most used families of MDs in chemometric practice. Therefore, it has been demonstrated to that the proposed MDs are useful in molecular design and permit obtaining easier and robust mathematical models than the majority of those reported in the literature. All this range of mentioned possibilities open "the doors" to the creation of a new family of MDs, using the graph derivative, and avail a new tool for QSAR/QSPR and molecular diversity/similarity studies.

On the Development and Use of Large Chemical Similarity Networks, Informatics Best Practices and Novel Chemical Descriptors Towards Materials Quantitative Structure Property Relationships

Science.gov (United States)

Krein, Michael

After decades of development and use in a variety of application areas, Quantitative Structure Property Relationships (QSPRs) and related descriptor-based statistical learning methods have achieved a level of infamy due to their misuse. The field is rife with past examples of overtrained models, overoptimistic performance assessment, and outright cheating in the form of explicitly removing data to fit models. These actions do not serve the community well, nor are they beneficial to future predictions based on established models. In practice, in order to select combinations of descriptors and machine learning methods that might work best, one must consider the nature and size of the training and test datasets, be aware of existing hypotheses about the data, and resist the temptation to bias structure representation and modeling to explicitly fit the hypotheses. The definition and application of these best practices is important for obtaining actionable modeling outcomes, and for setting user expectations of modeling accuracy when predicting the endpoint values of unknowns. A wide variety of statistical learning approaches, descriptor types, and model validation strategies are explored herein, with the goals of helping end users understand the factors involved in creating and using QSPR models effectively, and to better understand relationships within the data, especially by looking at the problem space from multiple perspectives. Molecular relationships are commonly envisioned in a continuous high-dimensional space of numerical descriptors, referred to as chemistry space. Descriptor and similarity metric choice influence the partitioning of this space into regions corresponding to local structural similarity. These regions, known as domains of applicability, are most likely to be successfully modeled by a QSPR. In Chapter 2, the network topology and scaling relationships of several chemistry spaces are thoroughly investigated. Chemistry spaces studied include the

Physiologically Based Pharmacokinetic Modeling in Lead Optimization. 1. Evaluation and Adaptation of GastroPlus To Predict Bioavailability of Medchem Series.

Science.gov (United States)

Daga, Pankaj R; Bolger, Michael B; Haworth, Ian S; Clark, Robert D; Martin, Eric J

2018-03-05

When medicinal chemists need to improve bioavailability (%F) within a chemical series during lead optimization, they synthesize new series members with systematically modified properties mainly by following experience and general rules of thumb. More quantitative models that predict %F of proposed compounds from chemical structure alone have proven elusive. Global empirical %F quantitative structure-property (QSPR) models perform poorly, and projects have too little data to train local %F QSPR models. Mechanistic oral absorption and physiologically based pharmacokinetic (PBPK) models simulate the dissolution, absorption, systemic distribution, and clearance of a drug in preclinical species and humans. Attempts to build global PBPK models based purely on calculated inputs have not achieved the optimization. In this work, local GastroPlus PBPK models are instead customized for individual medchem series. The key innovation was building a local QSPR for a numerically fitted effective intrinsic clearance (CL loc ). All inputs are subsequently computed from structure alone, so the models can be applied in advance of synthesis. Training CL loc on the first 15-18 rat %F measurements gave adequate predictions, with clear improvements up to about 30 measurements, and incremental improvements beyond that.

A study on relationship between organizational climate and creativity

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Ali Akbar Ahmadi

2013-11-01

Full Text Available This study examines the relationship between organizational climate and women employees' creativity of Tabriz Red Crescent Organization. The research method is descriptive correlation performed among 120 women employed at the Red Crescent and 100 cases were selected for the proposed study. For data collection, Hoy and Miskel (2005's organizational climate and Randsyp creativity questionnaires with 0.78 and 0.82 Cronbach's alpha coefficients were used. Pearson correlation and multiple regressions were used to analyze research hypotheses. Results showed that there was a significant relationship between two indices of manager and subordinate behaviors and creativity. In addition, in investigating the relationship between climate and creativity components, findings showed that there was a significant relationship only between cooperation and pretending to job dimensions and creativity. This study also has shown that managers' behavior is closed and employees' behavior is more open than managers are.

Grid-based Continual Analysis of Molecular Interior for Drug Discovery, QSAR and QSPR.

Science.gov (United States)

Potemkin, Andrey V; Grishina, Maria A; Potemkin, Vladimir A

2017-01-01

free-orbital approach AlteQ is proposed. All the functions can be calculated using a quantum approach at a sufficient level of theory and their values can be determined in all lattice points for a molecule. Then, the molecules of a dataset can be superimposed in the lattice for the maximal coincidence (or minimal deviations) of the potentials (i) or the quantum functions (ii). The methods and criteria of the superimposition are discussed. After that a functional relationship between biological activity or property and characteristics of potentials (i) or functions (ii) is created. The methods of the quantitative relationship construction are discussed. New approaches for rational virtual drug design based on the intermolecular potentials and quantum functions are invented. All the invented methods are realized at www.chemosophia.com web page. Therefore, a set of 3D QSAR approaches for continual molecular interior study giving a lot of opportunities for virtual drug discovery, virtual screening and ligand-based drug design are invented. The continual elucidation of molecular structure is performed in the terms of intermolecular interactions potentials and in the terms of quantum functions such as electron density distribution, Laplacian and Hamiltonian of electron density distribution, potential energy distribution, the highest occupied and the lowest unoccupied molecular orbitals distribution and their superposition. To reduce time of calculations using quantum methods based on the first principles, an original quantum free-orbital approach AlteQ is proposed. The methods of the quantitative relationship construction are discussed. New approaches for rational virtual drug design based on the intermolecular potentials and quantum functions are invented. All the invented methods are realized at www.chemosophia.com web page. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

The Study of the Relationship between Mother's Studies with Study Skills and Mathematics Performance of Students

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Behnoush Taheri

2015-07-01

Full Text Available Certainly teaching study skills of mathematics has special importance and plays important role in mathematics performance of students. As mothers spend more times with self-children then they can be effect on study and their mathematics performance. Present research implements to study of the relationship between mothers' studies with study skills and mathematics performance of their children. Population of this research is all girl students of first grade in high school at zone one of Tehran and sample is 97 people. For collecting data of this research through standard questionnaire of mathematics studies skills is used for measuring of study skill of mathematics and questions for studying information related to mothers' studies and a math exam for getting information of mathematics performance of students are used. The results indicated that there is not significant relationship between mothers' studies and study skill of mathematics among students. Also, it is indicated that there is positive significant relationship between mothers' studies and mathematic performance of students.

Sibling relationships in individuals with Angelman syndrome: A comparative study

NARCIS (Netherlands)

Love, V.; Richters, L.P.H.; Didden, H.C.M.; Korzilius, H.P.L.M.; Machalicek, W.A.

2012-01-01

Objective: Investigating the impact of Angelman syndrome on the sibling relationship. Methods: This study explored differences in sibling relationships between children with a typically-developing sibling (n = 55) and children with a sibling with Angelman syndrome (n 44). Sibling relationships were

A study on relationship between emotional maturity and marital satisfaction

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Seyed Esmael Mosavi

2012-04-01

Full Text Available Marriage is one of the most important events of people's lives and when it happens, it could have both positive and negative consequences. In this paper, we present an empirical study to investigate the relationship between emotional maturity and marital satisfaction using a classical questionnaire. The study chooses all people aged 25-35 who live in region 10 of the city of Esfahan, Iran. The proposed study splits the main hypothesis into five detailed questions, which considers the relationship between marital satisfaction with five other components including emotional instability, return emotional, social maladjustment, close character and lack of independence. The results indicate a negative correlation between marital satisfaction and these items and t-student confirmed that there are meaningful relationship between marital satisfaction and emotional instability, return emotional, close character and lack of independence but there is no meaningful relationship between marital satisfaction and social maladjustment. In summary, the survey concluded that there is meaningful relationship between marital satisfaction and emotional maturity.

Relationship of Study Habits with Mathematics Achievement

Science.gov (United States)

Odiri, Onoshakpokaiye E.

2015-01-01

The study examined the relationship of study habits of students and their achievement in mathematics. The method used for the study was correlation design. A sample of 500 students were randomly selected from 25 public secondary schools in Delta Central Senatorial District, Delta State, Nigeria. Questionnaires were drawn to gather data on…

Are Sibling Relationships Protective? A Longitudinal Study

Science.gov (United States)

Gass, Krista; Jenkins, Jennifer; Dunn, Judy

2007-01-01

Background: Although the protective effects of familial and parental support have been studied extensively in the child psychopathology literature, few studies have explored the protective quality of positive sibling relationships. Methods: A two-wave longitudinal design was used to examine the protective effect of positive sibling relationships…

The challenges to intimacy and sexual relationships for gay men in HIV serodiscordant relationships: a pilot study.

Science.gov (United States)

Palmer, R; Bor, R

2001-10-01

Human Immunodeficiency Virus (HIV) infection and disease progression create imbalance in long-term, HIV-serodiscordant, gay male relationships, particularly in sexual relations and issues of physical and emotional intimacy. Stage of disease progression and worldview of the couple both affect the relationship and its survival. To redress imbalance, partners employ a range of coping strategies and techniques. This article explores these issues in the context of HIV serodiscordant gay couples and how they preserve their relationships in the face of these unique challenges. For workers who provide psychotherapeutic and community support for people with HIV and for their partners, the results of this study may be helpful in recognizing stress factors for couples, and tailoring support services to the needs of both partners. Overall, this study provides a basis for further work examining the dynamics of serodiscordant relationships.

A study on relationship between social capital and sustainable development

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Shabnam Fotovvat

2014-09-01

Full Text Available This paper presents an empirical investigation to study the relationship between social capital components, social trust, social cohesion, social participation and social security, and sustainable development in city of Salmas, Iran. The study designs a questionnaire in Likert scale, distributes it among 384 randomly selected people who live in this city. Cronbach alpha has been calculated as 0.92, which is well above the minimum acceptable level. Using regression technique, the study has determined a positive and meaningful relationship between three components of social capital and sustainable development including social cohesion, social participation and social security. However, the study does not confirm the relationship between social trust and sustainable development.

Quality of Sibling Relationship and Substance Misuse: A Comparative Study

OpenAIRE

Anastasia Tsamparli; Elvisa Frrokaj

2016-01-01

The aim of the current study is to examine the quality of sibling relationship in families with a sibling with substance misuse (SSU) and compare the relationship to families with a sibling with no use (SNU). Thirty-six (36) families participated in the study (17 with SSU and 19 with SNU; N = 144). Semi-structured interviews were conducted with 40 siblings (20 SNU and 20 SSU; 18-31 years old) in order to qualitatively investigate the characteristics of the sibling relationship. The siblings w...

A study on relationship between market share and cash flow policy

OpenAIRE

Somayeh Sadeghi Moghaddam; Fateme Zabihi

2014-01-01

This paper presents an empirical investigation to study the relationship between cash flow and market share on selected firms from Tehran Stock Exchange over the period 2007-2011. Using regression analysis, the study has detected a positive and meaningful relationship between cash flow on one side and three other investment opportunities, firm size and operating cash flow. In addition, there is a negative and meaningful relationship between leverage and cash flow. However, the study does not ...

CUSTOMER RELATIONSHIP MANAGEMENT : case study Coca-Cola Company

OpenAIRE

Ling, Xiaojing

2017-01-01

The Coca-Cola Company is an American multinational beverage corporation, a manufacturer, retailer and marketer of non-alcoholic beverage concentrates and syrups with its headquarter in Atlanta, Georgia. This thesis is aimed to affirm the superiority of the Coca-Cola Company and to find out its shortcomings in managing customer relationships based on studying the customer relationship management strategy for Coca-Cola Company and discussing the comparison between Coca-Cola and Pepsi Cola, then...

Multiphase, multicomponent phase behavior prediction

Science.gov (United States)

Dadmohammadi, Younas

Accurate prediction of phase behavior of fluid mixtures in the chemical industry is essential for designing and operating a multitude of processes. Reliable generalized predictions of phase equilibrium properties, such as pressure, temperature, and phase compositions offer an attractive alternative to costly and time consuming experimental measurements. The main purpose of this work was to assess the efficacy of recently generalized activity coefficient models based on binary experimental data to (a) predict binary and ternary vapor-liquid equilibrium systems, and (b) characterize liquid-liquid equilibrium systems. These studies were completed using a diverse binary VLE database consisting of 916 binary and 86 ternary systems involving 140 compounds belonging to 31 chemical classes. Specifically the following tasks were undertaken: First, a comprehensive assessment of the two common approaches (gamma-phi (gamma-ϕ) and phi-phi (ϕ-ϕ)) used for determining the phase behavior of vapor-liquid equilibrium systems is presented. Both the representation and predictive capabilities of these two approaches were examined, as delineated form internal and external consistency tests of 916 binary systems. For the purpose, the universal quasi-chemical (UNIQUAC) model and the Peng-Robinson (PR) equation of state (EOS) were used in this assessment. Second, the efficacy of recently developed generalized UNIQUAC and the nonrandom two-liquid (NRTL) for predicting multicomponent VLE systems were investigated. Third, the abilities of recently modified NRTL model (mNRTL2 and mNRTL1) to characterize liquid-liquid equilibria (LLE) phase conditions and attributes, including phase stability, miscibility, and consolute point coordinates, were assessed. The results of this work indicate that the ϕ-ϕ approach represents the binary VLE systems considered within three times the error of the gamma-ϕ approach. A similar trend was observed for the for the generalized model predictions using

[Study of the relationship between human quality and reliability].

Science.gov (United States)

Long, S; Wang, C; Wang, L i; Yuan, J; Liu, H; Jiao, X

1997-02-01

To clarify the relationship between human quality and reliability, 1925 experiments in 20 subjects were carried out to study the relationship between disposition character, digital memory, graphic memory, multi-reaction time and education level and simulated aircraft operation. Meanwhile, effects of task difficulty and enviromental factor on human reliability were also studied. The results showed that human quality can be predicted and evaluated through experimental methods. The better the human quality, the higher the human reliability.

Romantic Relationship Quality in the Digital Age: A Study with Young Adults.

Science.gov (United States)

Sánchez, Virginia; Muñoz-Fernández, Noelia; Ortega-Ruiz, Rosario

2017-05-03

Recent studies suggest that the online and offline behaviors young people display in romantic relationships are closely related. However, the differential effects of the dimensions of couple quality in the online context have not yet been explored in depth. The aim of this study was to explore online couple quality in young-adult relationships, and its association with romantic relationship satisfaction, also looking at effects of gender, age, and length of the relationship. 431 university students currently in a romantic relationship (68.2% females; mean age = 21.57) participated in this study. They completed different self-report measures to tap the online quality of their romantic relationships (online intimacy, control, jealousy, intrusiveness, cyberdating practices, and communication strategies) and level of satisfaction with those relationships. Results showed that participants more often reported online intimacy (M men = 2.49; M women = 2.38) than the negative scales of online quality (mean ranged from .43 to 1.50), and all the online quality scales decreased with age (correlations ranged from -.12 to -.30) and relationship length (correlations ranged from -.02 to -.20). Linear regression analyses indicated that online intimacy (b = .32, p = .001) and intrusiveness (b = .11, p = .035) were positively related to relationship satisfaction, while cyberdating practices (b = -.20, p = .001) and communication strategies (b = -.34, p = .001) were negatively correlated with relationship satisfaction. Moreover, gender and relationship length moderated some of these associations. Results indicate that while online quality and relationship satisfaction are related, the impact of different online quality dimensions on relationship satisfaction differs depending on a participant's sex, age, and relationship length.

The Close Relationships of People with Intellectual Disabilities: A Qualitative Study.

Science.gov (United States)

Sullivan, Faye; Bowden, Keith; McKenzie, Karen; Quayle, Ethel

2016-03-01

Positive interpersonal relationships have been found to enhance an individual's quality of life. However, people with intellectual disabilities (PWID) often have restricted social networks, and little is known about their views on close social relationships. The study aimed to explore how this group perceives and experiences close relationships. Ten (6 = men 4 = women) PWID participated. Data were collected using semi-structured interviews, and analysed using interpretive phenomenological analysis. The results report on three of five themes drawn from a larger qualitative study: 'Relationships feeling safe and being useful'; 'Who's in charge?' and 'Struggling for an ordinary life'. Close relationships are valued and desired by PWID, but a variety of barriers inhibit their development and maintenance. This includes the failure of others to value, accept and appropriately support the independence and relationships of PWID. Potential ways of addressing these issues are discussed. © 2015 John Wiley & Sons Ltd.

Students′ views on student-teacher relationship: A questionnaire-based study

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Khalid A Bin Abdulrahman

2007-01-01

Full Text Available Aim: The aim of this study is to assess students′ views on student-teacher relationship and its effect on academic grades. Methods: The present cross-sectional study was conducted in the College of Medicine, King Saud University, Riyadh, in 2005. The questionnaires were distributed to 420 students during the examination period in order to obtain a full response. It consisted of items on different aspects of student-teacher relationship for which the responses were measured on a 4-point scale. The response rate was about 83%. Results: The current relationship between the student and the teacher was evaluated as very good and good by 61% of the study sample. The responses were associated with their grades as (X [2] =6.25, p=0.012. Eighty-four point one percent of students with higher and above average grades felt that expulsion from class was an appropriate means of controlling the class. Also (78.2% students felt that the teachers treated them with respect, and their responses were significantly associated with their grades (X [2] =11.8, p=0.003. Eight-four percent of the students with higher and above average grades strongly agreed that teacher′s performance was affected by students′ attendance or absence and the responses were significantly associated with their grades (X [2] =4.35, p=0.037. The responses to most of the items by the students were independent of their grades. Conclusion: This study concludes that student-teacher relationship was good in a medical school and the views of students on this relationship were independent with their academic grades. Further study which includes from 1 st year to 5th year undergraduate students is required to give a broader view of student-teacher relationship in a medical school.

Synthesis of magnetite nanoparticles in the presence of aminoacids

International Nuclear Information System (INIS)

Marinescu, Gabriela; Patron, Luminita; Culita, Daniela C.; Neagoe, Cristian; Lepadatu, Costinel I.; Balint, Ioan; Bessais, Lotfi; Cizmas, Corneliu Bazil

2006-01-01

A new synthesis route to prepare magnetite nanoparticles in only one step is described. The precipitation of magnetite is performed in the presence of aminoacid solution. The experimental protocol is original and the nanomagnetites are characterized by XRD, FTIR, TEM and SQUID magnetometry. A theoretical study of the consistent experimental results was performed using QSPR (Quantitative Structure Property Relationsheep). According with these studies the synthesized nanoparticles seem to be organized into a core-shell system, where the inner-core is formed from unit cells of magnetite. A way to control the self-assembly and the physical properties of the synthesized nanoparticles consists in their correlation with descriptors representing the aminoacid chemical structures. Using quantum chemical as well as the other simplest original descriptors it was found a relationship between the used aminoacids and the magnetization, nanoparticles diameter, magnetite core diameter and the (Fe 3 O 4 ) 8 cells in each nanoparticle core

OPERA models for predicting physicochemical properties and environmental fate endpoints.

Science.gov (United States)

Mansouri, Kamel; Grulke, Chris M; Judson, Richard S; Williams, Antony J

2018-03-08

The collection of chemical structure information and associated experimental data for quantitative structure-activity/property relationship (QSAR/QSPR) modeling is facilitated by an increasing number of public databases containing large amounts of useful data. However, the performance of QSAR models highly depends on the quality of the data and modeling methodology used. This study aims to develop robust QSAR/QSPR models for chemical properties of environmental interest that can be used for regulatory purposes. This study primarily uses data from the publicly available PHYSPROP database consisting of a set of 13 common physicochemical and environmental fate properties. These datasets have undergone extensive curation using an automated workflow to select only high-quality data, and the chemical structures were standardized prior to calculation of the molecular descriptors. The modeling procedure was developed based on the five Organization for Economic Cooperation and Development (OECD) principles for QSAR models. A weighted k-nearest neighbor approach was adopted using a minimum number of required descriptors calculated using PaDEL, an open-source software. The genetic algorithms selected only the most pertinent and mechanistically interpretable descriptors (2-15, with an average of 11 descriptors). The sizes of the modeled datasets varied from 150 chemicals for biodegradability half-life to 14,050 chemicals for logP, with an average of 3222 chemicals across all endpoints. The optimal models were built on randomly selected training sets (75%) and validated using fivefold cross-validation (CV) and test sets (25%). The CV Q 2 of the models varied from 0.72 to 0.95, with an average of 0.86 and an R 2 test value from 0.71 to 0.96, with an average of 0.82. Modeling and performance details are described in QSAR model reporting format and were validated by the European Commission's Joint Research Center to be OECD compliant. All models are freely available as an open

Studying the electronic customer relationship management and its ...

African Journals Online (AJOL)

Studying the electronic customer relationship management and its effect on bank quality outcomes. ... Journal of Fundamental and Applied Sciences ... Keywords: Electronic Banking, Service Quality, Customer Satisfaction, Management of

Sibling relationships in individuals with Angelman syndrome: a comparative study.

Science.gov (United States)

Love, Victoria; Richters, Lotte; Didden, Robert; Korzilius, Hubert; Machalicek, Wendy

2012-01-01

Investigating the impact of Angelman syndrome on the sibling relationship. This study explored differences in sibling relationships between children with a typically-developing sibling (n = 55) and children with a sibling with Angelman syndrome (n = 44). Sibling relationships were compared on four factors and 16 sub-scales of the Sibling Relationship Questionnaire-Revised. Results showed significant differences in mean scores on each of the four factors (i.e. Warmth/Closeness, Conflict, Rivalry and Dominance/Nurturance) and most of the sub-scales. ANCOVAs showed that demographic variables (number of siblings, living in a two-parent vs single parent household, gender, participant's age, place of residence) did not influence significant differences in sibling relationships between the two groups. Having a brother or sister with Angelman syndrome may influence the way in which the sibling perceives the sibling relationship. This may have important implications for family-centred intervention for this population.

Studying the relationship between brand equity and consumer behavior

Directory of Open Access Journals (Sweden)

Satvati Razavi Shadi

2016-01-01

Full Text Available The present study was conducted to investigate the relationship between brand equity and consumer behavior. In today's competitive world, where the consumer is faced with a broad range of products made in different countries, companies should further seek to identify the factors of customers' trends towards products to encourage customers to select and purchase the product. In the model proposed in this study, the relationship between brand equity and the dimensions of consumer behavior including the willingness to pay for extra cost, brand preference and purchase intention is investigated. The research method is a descriptive correlational. Structural equations and descriptive and inferential statistics and factor analysis were used to analyze the data. The statistical population of the study includes the owners of Grand Vitara, Sportage and Santafe from the companies of Iran Khodro, Kia and Hyundai. The population was unlimited including 384 people using Cochran formula; and cluster sampling and endemic questionnaire tool were used. In the marketing literature, the lack of empirical research that seeks to explore the relationship between brand equity and consumer behavior is tangible. This research focuses on those reactions that provide more sales and the ability to grow. According to the results, it seems that there is a relationship between brand equity and consumer behavior including paying extra cost, brand preference and purchase intention.

An empirical study to measure the relationship between management style and conflict management

Directory of Open Access Journals (Sweden)

Saeed Moghaddas Pour

2012-10-01

Full Text Available Leadership plays an important role among five main components of management. These days, many organizations try to resolve any existing conflicts through adapting an appropriate leadership strategy. During the past few years, there are increasing interests in examining the relationship between management style and conflict management. The proposed study of this paper performs an empirical study to find the relationship between relationship-oriented leadership style and solution-oriented strategy as well as between leadership style and conflict management. The proposed study distributed a questionnaire among 43 managers who were in different industries in west part of Iran. Most of the people who participated in our survey were male and they were between 25 to 30 years old. The study considers relationship between leadership style and conflict management, which includes the relationship between relationship-oriented and task-oriented leaderships with avoiding conflict management strategy, solution and control based conflict managements. The results confirmed that there is only a meaningful relationship between relationship-oriented leadership with solution-based conflict management. In other words, our survey indicates that when there is a conflict, management can handle the problem using his/her relationship and find appropriate solution to resolve any possible conflict.

Experiences of Male Counselor Educators: A Study of Relationship Boundaries

Science.gov (United States)

Ray, Dee C.; Huffman, David D.; Christian, David D.; Wilson, Brittany J.

2016-01-01

This study surveyed male counselor educators regarding the impact of being male upon their professional relationships. Participants (N = 163) were surveyed about their attitudes concerning the influence of gender on their relational behavior, as well as their relationship practices with students and colleagues. Mixed-methods analyses revealed a…

Modeling the binding affinity of structurally diverse industrial chemicals to carbon using the artificial intelligence approaches.

Science.gov (United States)

Gupta, Shikha; Basant, Nikita; Rai, Premanjali; Singh, Kunwar P

2015-11-01

Binding affinity of chemical to carbon is an important characteristic as it finds vast industrial applications. Experimental determination of the adsorption capacity of diverse chemicals onto carbon is both time and resource intensive, and development of computational approaches has widely been advocated. In this study, artificial intelligence (AI)-based ten different qualitative and quantitative structure-property relationship (QSPR) models (MLPN, RBFN, PNN/GRNN, CCN, SVM, GEP, GMDH, SDT, DTF, DTB) were established for the prediction of the adsorption capacity of structurally diverse chemicals to activated carbon following the OECD guidelines. Structural diversity of the chemicals and nonlinear dependence in the data were evaluated using the Tanimoto similarity index and Brock-Dechert-Scheinkman statistics. The generalization and prediction abilities of the constructed models were established through rigorous internal and external validation procedures performed employing a wide series of statistical checks. In complete dataset, the qualitative models rendered classification accuracies between 97.04 and 99.93%, while the quantitative models yielded correlation (R(2)) values of 0.877-0.977 between the measured and the predicted endpoint values. The quantitative prediction accuracies for the higher molecular weight (MW) compounds (class 4) were relatively better than those for the low MW compounds. Both in the qualitative and quantitative models, the Polarizability was the most influential descriptor. Structural alerts responsible for the extreme adsorption behavior of the compounds were identified. Higher number of carbon and presence of higher halogens in a molecule rendered higher binding affinity. Proposed QSPR models performed well and outperformed the previous reports. A relatively better performance of the ensemble learning models (DTF, DTB) may be attributed to the strengths of the bagging and boosting algorithms which enhance the predictive accuracies. The

Study on the relationship between participatory management in ...

African Journals Online (AJOL)

Journal of Fundamental and Applied Sciences ... The aim of this study was to examine the relationship between social capital growths with use of ... For the analysis, descriptive and inferential statistical methods (Pearson correlation coefficient, ...

An observational study on the relationship between plasma vitamin ...

African Journals Online (AJOL)

ARTICLE. An observational study on the relationship between plasma ... To study plasma vitamin C, oxidative stress, hyperglycaemia, endothelial dysfunction and outcome in septic shock. ..... with critical illness,[6,7,16] and excess losses of.

Enabling online studies of conceptual relationships between medical terms: developing an efficient web platform.

Science.gov (United States)

Albin, Aaron; Ji, Xiaonan; Borlawsky, Tara B; Ye, Zhan; Lin, Simon; Payne, Philip Ro; Huang, Kun; Xiang, Yang

2014-10-07

The Unified Medical Language System (UMLS) contains many important ontologies in which terms are connected by semantic relations. For many studies on the relationships between biomedical concepts, the use of transitively associated information from ontologies and the UMLS has been shown to be effective. Although there are a few tools and methods available for extracting transitive relationships from the UMLS, they usually have major restrictions on the length of transitive relations or on the number of data sources. Our goal was to design an efficient online platform that enables efficient studies on the conceptual relationships between any medical terms. To overcome the restrictions of available methods and to facilitate studies on the conceptual relationships between medical terms, we developed a Web platform, onGrid, that supports efficient transitive queries and conceptual relationship studies using the UMLS. This framework uses the latest technique in converting natural language queries into UMLS concepts, performs efficient transitive queries, and visualizes the result paths. It also dynamically builds a relationship matrix for two sets of input biomedical terms. We are thus able to perform effective studies on conceptual relationships between medical terms based on their relationship matrix. The advantage of onGrid is that it can be applied to study any two sets of biomedical concept relations and the relations within one set of biomedical concepts. We use onGrid to study the disease-disease relationships in the Online Mendelian Inheritance in Man (OMIM). By crossvalidating our results with an external database, the Comparative Toxicogenomics Database (CTD), we demonstrated that onGrid is effective for the study of conceptual relationships between medical terms. onGrid is an efficient tool for querying the UMLS for transitive relations, studying the relationship between medical terms, and generating hypotheses.

High School Football Players and Their Coaches: A Qualitative Study of Their Relationships

Science.gov (United States)

Skaza, Robert J.

2014-01-01

This basic qualitative study of high school football coach-player relationships explores the players' perceptions of these relationships, specifically the perceptions the players have of how these relationships influenced their lives. This study allowed the researcher to examine the characteristics of high school football coaches as they relate to…

The relationships between work characteristics and mental health: Examining normal, reversed and reciprocal relationships in a 4-wave study

NARCIS (Netherlands)

Lange, A.H. de; Taris, T.W.; Kompier, M.A.J.; Houtman, I.L.D.; Bongers, P.M.

2004-01-01

This longitudinal study examined the causal relationships between job demands, job control and supervisor support on the one hand and mental health on the other. Whereas we assumed that work characteristics affect mental health, we also examined reversed causal relationships (mental health

"If you don't have honesty in a relationship, then there is no relationship": African American girls' characterization of healthy dating relationships, a qualitative study.

Science.gov (United States)

Debnam, Katrina J; Howard, Donna E; Garza, Mary A

2014-12-01

The quality of dating relationships in adolescence can have long lasting effects on identity development, self-esteem, and interpersonal skills, and can shape values and behaviors related to future intimate relationships. The aims of this study were to: (1) investigate how African American adolescent girls characterize healthy relationships; and (2) describe the meanings of these characteristics in the context of the Centers for Disease Control and Prevention's (CDC) 12 healthy dating relationship qualities. We conducted semi-structured one-on-one in-depth interviews with 33 African American high school girls in the mid-Atlantic region. Trained staff transcribed interviews verbatim and entered the data into ATLAS.ti for coding and analysis. Participants' specified and vividly described eight healthy relationship characteristics: good communication, honesty, trust, respect, compromise, understanding, individuality, and self-confidence. Of these characteristics, three (good communication, compromise, and respect) were described in ways discordant with CDC's definitions. Findings highlight a need to better understand how girls develop values and ascribe characteristics of healthy relationships in order to reduce their risk for teen dating violence.

Journalists and Olympic athletes: a Norwegian case study of ambivalent relationship

OpenAIRE

Kristiansen, Elsa; Hanstad, Dag Vidar

2012-01-01

© 2012 Human Kinetics This case study explores the relationship between media and sport. More specifically, it examines the association (i.e., the contact and communication) between Norwegian journalists and athletes during the 2010 Olympic Winter Games in Vancouver, Canada. Ten athletes and three journalists were interviewed about their relationship. To regulate and improve the journalist–athlete relationship during special events like the Olympics, media rules have been formulated. In re...

Relationship satisfaction in women: a longitudinal case-control study about the role of breast cancer, personal assertiveness, and partners' relationship-focused coping.

Science.gov (United States)

Hinnen, Chris; Hagedoorn, Mariët; Ranchor, Adelita V; Sanderman, Robbert

2008-11-01

The aim of this study was to investigate whether a breast cancer diagnosis, personal assertiveness (i.e. frequency of assertive behaviour and tension associated with this behaviour), and partners' relationship-focused coping (i.e. active engagement and protective buffering) were sources of variation in patients' relationship satisfaction, cross-sectionally and over time. This longitudinal case-control study assessed the two dimensions of personal assertiveness and relationship satisfaction in both women with cancer (N=72) and comparison controls (N=62). In addition, patients completed a measure assessing their partners' active engagement and protective buffering. Cases (i.e. women with breast cancer) were not found to report more relationship problems than controls. Women with breast cancer who tended not to express their concerns and feelings and who experienced much tension when they did, reported relatively low marital satisfaction. Moreover, partners' protective buffering was associated with less relationship satisfaction in especially more assertive (i.e. high frequency of assertive behaviour and low tension) women with cancer, while active engagement was associated with more relationship satisfaction, regardless of the women's personal assertiveness. The results of the present study indicate that a breast cancer diagnosis by itself may not be a risk factor for relationship problems. However, in the context of an illness such as cancer, personal assertiveness, and a partner's relationship-focused coping strategies do seem to play a role in maintaining a satisfactory relationship with one's partner.

Newly synthesized benzanthrone derivatives as prospective fluorescent membrane probes

International Nuclear Information System (INIS)

Zhytniakivska, Olga; Trusova, Valeriya; Gorbenko, Galyna; Kirilova, Elena; Kalnina, Inta; Kirilov, Georgiy; Kinnunen, Paavo

2014-01-01

Fluorescence spectral properties of a series of novel benzanthrone derivatives have been explored in lipid bilayers composed of zwitterionic lipid phosphatidylcholine (PC) and its mixtures with cholesterol (Chol) and anionic phospholipid cardiolipin (CL). Analysis of partition coefficients showed that all the examined compounds possess rather high lipid-associating ability, with the amidino derivatives exhibiting stronger membrane partitioning compared with the aminobenzanthrones. To understand how benzanthrone partition properties correlate with their structure, quantitative structure property relationship (QSPR) analysis was performed involving a range of quantum chemical molecular descriptors. -- Highlights: • Benzanthrone partitioning into lipid bilayer correlates with lipophilicity of the dyes. • Partition properties of benzanthrones depend on the dye dipole moment. • Amidino derivatives exhibit higher membrane affinity than aminobenzanthrones

A Study on Marketing Management Tool use of Customer Relationship

Directory of Open Access Journals (Sweden)

Cibele Barsalini Martins

2015-04-01

Full Text Available This paper highlights the relation between management tools of Relationship Marketing (RM with customers. The auxiliary tools in the process of Relationship Marketing were analyzed: Customer Relationship Management (CRM, Loyalty Programs, Endomarketing and Marketing Research. This study presented a multicase comparative in six companies, in which three of them have already deployed the management of Relationship Marketing with their clients, and the other three companies that were in the preliminary phase of deployment of these. The data collection was made from semi-structured interviews with professionals who worked in three hierarchical levels (strategic, tactical, and operational of each participating company, using both the technique of data collection by e-mail and personal interview. The approach was qualitative, with phenomenological analysis. It was found that the deployment of Relationship Marketing by the organizations surveyed takes place in a significant amount of time, where investments have occurred by pressure of the environment, in particular by loss of market share, the need to promote customer loyalty, to improve competitiveness and concern with the customer. It was not clear that the process of deployment of Relationship Marketing originated from the strategic planning and used proactively.

Business-Community Relationships for Extractive Industries: A Case Study in Peru

Directory of Open Access Journals (Sweden)

Jose Ventura

2017-07-01

Full Text Available Natural resource-based economies have long relied on foreign demand to fuel their growth. For instance, the extractive sectors in Peru have experienced a rapid expansion, driven by a rising demand for commodities. Alongside economic growth, extractive operations have triggered social and environmental concerns among the various stakeholders, thus resulting in either social conflict or a deterioration of the relationship between companies in the extractive industries and local communities. In this context, the purpose of this paper is to understand the relationships between companies in the extractive industries and rural families. This research uses the case-study method. The findings show that a trustful relationship is supported by a beneficiary-society approach that builds upon philanthropic and ethical types of relationships. Unlike the type of relationship based on economic or legal interests, a trust-based relationship offers avenues for managing social conflict that have yet to be explored.

A STUDY OF RELATIONSHIP BETWEEN INTERNET USAGE AND SELF-REGULATED LEARNING OF UNDERGRADUATES

OpenAIRE

Dr. Meena Prakash Kute; SadhanaPote-Palsamkar

2017-01-01

The present paper is based on the descriptive correlational research study which aimed to study the relationship between internet usage and self-regulated learning of undergraduates. The survey method was employed to collect the data from commerce, science and arts undergraduates of Mumbai University. The findings of present study showed that, there is significant relationship between internet usage and self-regulated learning of undergraduates. The relationship was found to be positive and n...

Analysis of Relationship between Knowledge Management and Customer Relationship Management with Customer Knowledge Management (Case Study At Azaran Valve Co.)

OpenAIRE

Sayyed Mohsen Allameh; Arash Shahin; Babak Tabanifar

2012-01-01

Knowledge management (KM) and customer relationship management (CRM) are both emphasized on the allocation of resources to business supportive activities in order to gain competitive advantages.. Merging the two concepts of knowledge management and customer relationship management in customer knowledge management (CKM) model can promote the benefits of employing each of them and reduce the risk of implementation failure. This study sought to analyze the relationship between knowledge manageme...

Empirical Study Regarding the Trust Relationships Established in a Community

Directory of Open Access Journals (Sweden)

Florina-Valentina NICOLAE

2016-12-01

Full Text Available The paper that we present aims to address the issue of relationships naturally established in a community through some items that we consider relevant to the proposed topic. In this purpose, we have initiated a quantitative research, developed through a survey, based on questionnaire, self-managed and on line. The recorded answers are statistically interpreted, using IBM SPSS application. The results suggests that the perception of the subjects participating in the study on the relationships established with their communities, on the date of the study, is not clearly contoured.

Measurement and ANN prediction of pH-dependent solubility of nitrogen-heterocyclic compounds.

Science.gov (United States)

Sun, Feifei; Yu, Qingni; Zhu, Jingke; Lei, Lecheng; Li, Zhongjian; Zhang, Xingwang

2015-09-01

Based on the solubility of 25 nitrogen-heterocyclic compounds (NHCs) measured by saturation shake-flask method, artificial neural network (ANN) was employed to the study of the quantitative relationship between the structure and pH-dependent solubility of NHCs. With genetic algorithm-multivariate linear regression (GA-MLR) approach, five out of the 1497 molecular descriptors computed by Dragon software were selected to describe the molecular structures of NHCs. Using the five selected molecular descriptors as well as pH and the partial charge on the nitrogen atom of NHCs (QN) as inputs of ANN, a quantitative structure-property relationship (QSPR) model without using Henderson-Hasselbalch (HH) equation was successfully developed to predict the aqueous solubility of NHCs in different pH water solutions. The prediction model performed well on the 25 model NHCs with an absolute average relative deviation (AARD) of 5.9%, while HH approach gave an AARD of 36.9% for the same model NHCs. It was found that QN played a very important role in the description of NHCs and, with QN, ANN became a potential tool for the prediction of pH-dependent solubility of NHCs. Copyright © 2015 Elsevier Ltd. All rights reserved.

The relationship between obesity and elderly suicide rates: a cross-national study

Directory of Open Access Journals (Sweden)

Ajit Shah

2010-07-01

Full Text Available BACKGROUND: An inverse relationship between obesity and suicide has been observed in younger adults, but this has not been examined in the elderly. METHODS: A cross-national ecological study examined the independent relationship between the prevalence of obesity and elderly suicide rates, by controlling for potentially confounding variables, using data from the World Health Organization and the United Nations. RESULTS: Elderly suicide rates in females were independently associated with the prevalence of obesity. CONCLUSIONS: Caution should be exercised in attributing a causal relationship from this cross-sectional ecological study due to ecological fallacy and requires confirmation in individual-level case-control or cohort studies.

Relationship Contracting: The South Australian Experience - A Case Study

Directory of Open Access Journals (Sweden)

Jian Zou

2012-11-01

Full Text Available The construction industry has long been accusedof poor performance. The confrontational attitudeof its members and the resultant adversarial atmosphere has been identified as a major factor responsible for this poor performance. A cultural change is required to remove these barriers and to promote optimum project outcomes. Relationship contracting is promoted as a way to support the shift from the adversarial culture to the co-operative and collaborative culture within the industry and the project team.The Adelaide Convention Centre Extensions project was the first in South Australia to be procure und r the principles of relationship contract1ng. Usmg the case study approach, this paper reviews the form of relationship contracting used in this milestone project. The paper documents the lessons learned from this project and makes recommendations that can lead to improvements for future projects.

The Close Relationships of People with Intellectual Disabilities: A Qualitative Study

Science.gov (United States)

Sullivan, Faye; Bowden, Keith; McKenzie, Karen; Quayle, Ethel

2016-01-01

Background: Positive interpersonal relationships have been found to enhance an individual's quality of life. However, people with intellectual disabilities (PWID) often have restricted social networks, and little is known about their views on close social relationships. The study aimed to explore how this group perceives and experiences close…

An empirical study to measure the relationship between management style and conflict management

OpenAIRE

Saeed Moghaddas Pour; Alireza Bakhshi Zadeh; Elham Barati

2012-01-01

Leadership plays an important role among five main components of management. These days, many organizations try to resolve any existing conflicts through adapting an appropriate leadership strategy. During the past few years, there are increasing interests in examining the relationship between management style and conflict management. The proposed study of this paper performs an empirical study to find the relationship between relationship-oriented leadership style and solution-oriented strat...

Assessing physician/patient relationships in the presence of HIV/AIDS: an exploratory study.

Science.gov (United States)

Taylor, S A; Madrigal, C

1998-01-01

The following study investigates the nature of the relationship between physicians and HIV/AIDS patients within the context of the rapidly evolving services/relationship marketing literatures. The emerging evidence suggests that service providers generally play a critical role in the development of positive consumer attitudes and behaviors, and that relationship marketing practices can contribute to the delivery of health services. However, to date, there appears little evidence supporting the efficacy of employing relationship marketing practices in relation to a target market of HIV/AIDS patients. This exploratory study contributes to the body of knowledge by more closely investigating the nature of the patient-physician relationship relative to HIV/AIDS patients' attitudes, marketing-related behaviors, and overall quality-of-life/life satisfaction judgments. The results of this study first suggest that HIV/AIDS patients use the expectancy disconfirmation model when evaluating the performance of their physician. A reliance on expectancy disconfirmation suggests the likely prevalent role of service quality perceptions and satisfaction judgments in evaluating their relationship with their physician. Second, the results appear to support the conclusion that the patient's evaluation of their physician relationship and subsequent behaviors (e.g., word-of-mouth) are directly related to the patient's general perception of received health services. Thus, the patient/physician relationship may play a particularly powerful role in determining patient (marketing related) outcomes relative to other health service settings. Third, a direct influence is supported between negative affective reactions by patients and subsequent outcome behaviors. This finding lends support for the potential efficacy of service recovery efforts when rendering treatment to HIV/AIDS patients. Finally, evidence is presented demonstrating the effect of positive perceptions of the patient

Some Formulas for the Polynomials and Topological Indices of Nanostructures

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Soleimani Najmeh

2016-12-01

Full Text Available In this paper, we focus on the structure of Polycyclic Aromatic Hydrocarbons (PAHs and calculate the Omega and its related counting polynomials of nanostructures. Also, the exact expressions for the Theta, Sadhana, Pi, Hyper Zagreb and Forgotten Zagreb indices of linear [n]-Tetracene, V-Tetracenic nanotube, H-Tetracenic nanotube and Tetracenic nanotori were computed for the first time. These indices can be used in QSAR/QSPR studies.

Relationship Between Epistaxis And Hypertension: A Study Of ...

African Journals Online (AJOL)

Both epistaxis and hypertension are common in the general population. This study aimed at determining the prevalence of hypertension among epistaxics, and the relationship between epistaxis and hypertension. Retrospective analysis of 62 adults comprising 31 each of males and females with a mean age of 41.4 ± 16.6 ...

Physician-management relationships at HCA: a case study.

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Campbell, P; Kane, N M

1990-01-01

The questions of whether Hospital Corporation of America (HCA), a for-profit hospital company, fostered an environment detrimental to the physician-patient relationship during the period of implementation of the Medicare Prospective Payment System (PPS) was explored. The transition to PPS provided an opportunity to evaluate whether hospital ownership differences affected responses to a payment system which encouraged institutional intervention in the practice of medicine. A case study approach was used to observe the influence of the then largest for-profit hospital corporation upon physicians' medical practice in four owned hospitals. Findings indicated that HCA hospital managers were most directly influenced by the local competitive environment and their own personal agendas in responding to PPS incentives. Corporate influence actually softened payment system incentives to intervene in medical practice by providing a generous supply of capital, and by fostering a corporate culture conducive to cooperative relationships with physicians. Better public understanding of the determinants of hospital behavior is needed to preserve or enhance important social goals such as the physician-patient relationship; easily measurable characteristics such as ownership or bed size explain little about hospital behavior or motivation.

Machiavellianism, Relationship Satisfaction, and Romantic Relationship Quality

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Gayle Brewer

2017-08-01

Full Text Available Machiavellianism is characterised by a manipulative interpersonal style, willingness to exploit others, and a preference for emotionally detached relationships. The present studies investigate the extent to which Machiavellianism influences relationship satisfaction and romantic relationship quality. In Study 1, 194 heterosexual partnered women completed Machiavellianism and Relationship Satisfaction measures. Women with higher levels of Machiavellianism reported lower levels of relationship satisfaction. In Study 2, 132 heterosexual partnered women completed Machiavellianism, Trust, Commitment, Control, and Emotional Abuse scales. Women with higher levels of Machiavellianism perceived their partners to be less dependable, reported less faith in their partners, and were less willing to persist with the relationship than those with low levels of Machiavellianism. With regards to negative behavior, Machiavellianism predicted each form of control and emotional abuse investigated, such that those with high levels of Machiavellianism were more likely to engage in controlling behavior and emotional abuse. Findings have important implications for the prediction of romantic relationship quality and in particular for negative behavior such as control and abuse.

How to get lost customers back? : a study of antecedents of relationship revival

OpenAIRE

Homburg, Christian; Hoyer, Wayne D.; Stock-Homburg, Ruth

2006-01-01

Most research in the field of customer relationship management has focused on keeping existing customers. However, some companies also systematically address lost customers and try to revive these relationships. This facet of customer relationship management has been largely neglected by academic research. Our study provides a theoretical discussion and an empirical analysis of factors driving the success of relationship revival activities. Drawing on equity theory we find that the cust...

Genetic Thinking in the Study of Social Relationships: Five Points of Entry.

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Reiss, David

2010-09-01

For nearly a generation, researchers studying human behavioral development have combined genetically informed research designs with careful measures of social relationships such as parenting, sibling relationships, peer relationships, marital processes, social class stratifications, and patterns of social engagement in the elderly. In what way have these genetically informed studies altered the construction and testing of social theories of human development? We consider five points of entry where genetic thinking is taking hold. First, genetic findings suggest an alternative scenario for explaining social data. Associations between measures of the social environment and human development may be due to genes that influence both. Second, genetic studies add to other prompts to study the early developmental origins of current social phenomena in midlife and beyond. Third, genetic analyses promise to shed light on understudied social systems, such as sibling relationships, that have an impact on human development independent of genotype. Fourth, genetic analyses anchor in neurobiology individual differences in resilience and sensitivity to both adverse and favorable social environments. Finally, genetic analyses increase the utility of laboratory simulations of human social processes and of animal models. © The Author(s) 2010.

Inter-professional relationships issues among iranian nurses and physicians: A qualitative study

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Samaneh Nakhaee

2017-01-01

Full Text Available Introduction: Nurse–physician inter-professional relationship is an important issue in health care system that can affect job satisfaction and patient care quality. The present study explores the major issues of nurse–physician inter-professional relationships in Iran. Materials and Methods: In this in-depth qualitative content analysis study conducted in 2014, 12 participants (5 physicians and 7 nurses were recruited from two educational hospitals. The data were collected from deep, open, and unstructured interviews, and analyzed based on content analysis. Results: The participants in this study included 12 individuals, 6 females and 6 males, with the age ranging 27–48 years and tenure ranging 4–17 years. Four themes were identified, namely, divergent attitudes, uneven distribution of power, mutual trust destructors, and prudence imposed on nurses. Conclusions: The results revealed some major inter-professional issues and challenges in nurse–physician relationships, some of which are context-specific whereas others should be regarded as universal. It is through a deep knowledge of these issues that nurses and physicians can establish better collaborative inter-professional relationships.

[The relationship study on the relationship between procrastination behaviors and bad personality disposition].

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Wei, Yuan

2006-01-01

To explore the relationship between procrastinate behavior of college students and bad personality disposition. 566 college students were selected and followed through adopting the measurement on the procrastination scale of college students and Personality Disorders Questionnaire (PDQ-4). Results showed that male and female college students did not have remarkable difference in terms of procrastination. High level procrastinators had a higher level of scores on bad personality disposition. In addition, College students' procrastination had close relationship with bad personality disposition (r = 0.341, P College students' procrastination had close relationship with bad personality disposition which did not match the findings from McCown's results on american college students.

The relationship between students’ study habits, happiness and depression

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Bahrami, Susan; Rajaeepour, Saeed; Rizi, Hasan Ashrafi; Zahmatkesh, Monereh; Nematolahi, Zahra

2011-01-01

BACKGROUND: One of the important requirements for cultural, social and even economic development is having a book-loving nation. In order to achieve this, there is a need for purposeful and continuous programming. The purpose of this research was to determine the relationship between students’ study habits, happiness and depression in Isfahan University of Medical Science. METHODS: This research was a kind of descriptive and correlation survey. Statistical population included all MSc and PhD students in the second semester of the Isfahan University of Medical Science (263 students). In this research, stratified and random sampling was used in which a sample of 100 students was selected. Data collection instruments were Beck Depression Inventory (BDI), Oxford Happiness Inventory and a researcher-made questionnaire to determine the amount of students’ study. Validity of this questionnaires was determined by structure and content related validity and its reliability was calculated by Cronbach's alpha coefficient for the first (r = 0.94), second (r = 0.91) and third (r = 0.85) questionnaire. Analysis of research findings was done through descriptive and inferential statistics. RESULTS: Findings showed that 68.8 percent of students study less than 5 hours and only 2.5 percent of students study more than 10 hours. 65 percent of students had high amount of happiness and 35 percent had medium amount of happiness. In 60 percent of students there was no symptom of depression and 7.5 had depression symptoms. Also, there was no significant relationship between happiness and studying but there was a significant and negative relationship between studying and depression and happiness and depression. CONCLUSIONS: The amount of study and tendency for reading are among the most important indices of human growth in terms of potential abilities for achieving a perfect human life and to prevent one-dimensional thinking. Thus, finding ways to encourage students to study is

The relationship between students' study habits, happiness and depression.

Science.gov (United States)

Bahrami, Susan; Rajaeepour, Saeed; Rizi, Hasan Ashrafi; Zahmatkesh, Monereh; Nematolahi, Zahra

2011-01-01

One of the important requirements for cultural, social and even economic development is having a book-loving nation. In order to achieve this, there is a need for purposeful and continuous programming. The purpose of this research was to determine the relationship between students' study habits, happiness and depression in Isfahan University of Medical Science. This research was a kind of descriptive and correlation survey. Statistical population included all MSc and PhD students in the second semester of the Isfahan University of Medical Science (263 students). In this research, stratified and random sampling was used in which a sample of 100 students was selected. Data collection instruments were Beck Depression Inventory (BDI), Oxford Happiness Inventory and a researcher-made questionnaire to determine the amount of students' study. Validity of this questionnaires was determined by structure and content related validity and its reliability was calculated by Cronbach's alpha coefficient for the first (r = 0.94), second (r = 0.91) and third (r = 0.85) questionnaire. Analysis of research findings was done through descriptive and inferential statistics. Findings showed that 68.8 percent of students study less than 5 hours and only 2.5 percent of students study more than 10 hours. 65 percent of students had high amount of happiness and 35 percent had medium amount of happiness. In 60 percent of students there was no symptom of depression and 7.5 had depression symptoms. Also, there was no significant relationship between happiness and studying but there was a significant and negative relationship between studying and depression and happiness and depression. The amount of study and tendency for reading are among the most important indices of human growth in terms of potential abilities for achieving a perfect human life and to prevent one-dimensional thinking. Thus, finding ways to encourage students to study is considered essential to achieve a healthy and developed

Bulimia and Interpersonal Relationships: A Longitudinal Study.

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Thelen, Mark H.; And Others

1990-01-01

Assessed changes in bulimia in female college students (N=44) and in relation between bulimia and interpersonal relationships over time. Found (1) stable symptomology for normals and bulimics; (2) strong negative correlations between bulimia measures and interpersonal relationships with men; and (3) improvement in symptomology and relationships…

A study on relationship between organizational culture and organizational commitment

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Maryam Khalili

2014-07-01

Full Text Available This paper presents an empirical investigation to study the relationship between organizational culture and organization commitment. The study uses two questionnaires, one for measuring organizational commitment originally developed by Meyer and Allen (1991 [Meyer, J. P., & Allen, N. J. (1991. A three-component conceptualization of organizational commitment. Human resource management review, 1(1, 61-89.] and the other one for organizational culture developed by Denison and Spreitzer (1991 [Denison, D. R., & Spreitzer, G. M. (1991. Organizational culture and organizational development: A competing values approach. Research in organizational change and development, 5(1, 1-21.]. The study is accomplished among selected full time employees who work for an Iranian bank named Bank Saderat Iran. Using Pearson correlation test as well as linear regression methods, the study has determined that there were some positive and meaningful relationship between all components of organizational commitment and organizational culture.

Recent Developments in the Study of Social Relationships, Stress Responses, and Physical Health

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Hostinar, Camelia E.

2015-01-01

This selective review aims to highlight some of the most recent empirical or theoretical advancements in the study of social relationships as buffers against stress and as protective factors against risk for disease, focusing on articles published between 2013 and 2015. The review summarizes novel findings showing that social relationships can protect individuals against negative health outcomes associated with chronic adversity and can be associated with reduced cumulative physiological damage (allostatic load). There is also evidence that some relationships can be a source of stress. Additionally, recent findings concerning the psychological and neurobiological mechanisms of action for social support, the developmental patterning of social stress-buffering and recent experimental studies attempting to change relationships to affect health are also reviewed. PMID:26366429

Conference Essay: The Relationship between Gender Studies and Discourse Studies: Synergies, Frictions, and Pitfalls

OpenAIRE

Kleiner, Bettina; Dinsleder, Cornelia

2017-01-01

The interdisciplinary conference "Gender Studies Meets Discourse Studies Meets Gender Studies: Entanglements, Affinities, Tensions, and Open Questions" focused on the relationship between gender studies and discourse studies. On the one hand this essay provides insights into the conference debates, and on the other it critically discusses the contributions. The following three key aspects provide guidelines for reconstructing and developing the arguments: 1. theoretical perspectives on the re...

Intergenerational Transmission Effects on Relationship Satisfaction: A Cross-Cultural Study

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Yoshida, Keitaro; Busby, Dean M.

2012-01-01

Although intergenerational transmission processes have been studied on various aspects of family life, cross-cultural comparisons have rarely been made. In the present study, the authors examine how intergenerational transmission processes on relationship satisfaction differ between individuals with different gender and cultural identities. A…

Social relationships and risk of dementia: a population-based study.

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Sörman, Daniel Eriksson; Rönnlund, Michael; Sundström, Anna; Adolfsson, Rolf; Nilsson, Lars-Göran

2015-08-01

The objective was to examine whether aspects of social relationships in old age are associated with all-cause dementia and Alzheimer's disease (AD). We studied 1,715 older adults (≥ 65 years) who were dementia-free at baseline over a period of up to 16 years. Data on living status, contact/visit frequency, satisfaction with contact frequency, and having/not having a close friend were analyzed using Cox proportional hazards regressions with all-cause dementia or AD as the dependent variable. To control for reverse causality and to identify potential long-term effects, we additionally performed analyses with delayed entry. We identified 373 incident cases of dementia (207 with AD) during follow-up. The variable visiting/visits from friends was associated with reduced risk of all-cause dementia. Further, a higher value on the relationships index (sum of all variables) was associated with reduced risk of all-cause dementia and AD. However, in analyses with delayed entry, restricted to participants with a survival time of three years or more, none of the social relationship variables was associated with all-cause dementia or AD. The results indicate that certain aspects of social relationships are associated with incident dementia or AD, but also that these associations may reflect reverse causality. Future studies aimed at identifying other factors of a person's social life that may have the potential to postpone dementia should consider the effects of reverse causality.

An empirical study on relationship between organizational culture and administrative corruption

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Saeed Sehhat

2012-08-01

Full Text Available Bureaucratic corruption is an organizational phenomenon, which faces the trend of countries’ development with serious problems. In spite of all planning and respects of countries to fight against this phenomenon, we are still observing its growth in various aspects of the community. The basic approach emphasized by present study is that it is necessary to establish a corruption prevention system whose central element is social culture and organizational culture rather than relying upon the trends based on punishment after corruption. To perceive the relationship between organizational culture and bureaucratic health of organizations, we used a field approach and selected four governmental organizations namely “governorship”, “municipality”, “traffic police” and “customs to gather the data. We used two questionnaires A and B to gather the data on organizational culture and the relationship between culture and corruption, respectively. Initially, by distributing questionnaire A, we evaluated all four organizations in a manner that two organizations have bureaucratic culture and two organizations with organic culture. Then, questionnaire B was distributed among employees and clients of studied organizations (to acquire realer information on bureaucratic health rate to study the relationship between the type of organizational culture and bureaucratic health. Research statistical population consists of all employees and clients of bureaucratic organizations in Chabahar province located in south east of Iran. Statistical sample consists of 146 clients and 146 employees of all four studied organizations. The results from data analysis show that there is no significant relationship between organic or mechanic organizational culture and employees’ bureaucratic health.

Social relationships and cognitive decline: a systematic review and meta-analysis of longitudinal cohort studies.

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Kuiper, Jisca S; Zuidersma, Marij; Zuidema, Sytse U; Burgerhof, Johannes Gm; Stolk, Ronald P; Oude Voshaar, Richard C; Smidt, Nynke

2016-08-01

Although poor social relationships are assumed to contribute to cognitive decline, meta-analytic approaches have not been applied. Individual study results are mixed and difficult to interpret due to heterogeneity in measures of social relationships. We conducted a systematic review and meta-analysis to investigate the relation between poor social relationships and cognitive decline. MEDLINE, Embase and PsycINFO were searched for longitudinal cohort studies examining various aspects of social relationships and cognitive decline in the general population. Odds ratios (ORs) with 95% confidence intervals (CIs) were pooled using random effects meta-analysis. Sources of heterogeneity were explored and likelihood of publication bias was assessed. We stratified analyses according to three aspects of social relationships: structural, functional and a combination of these. We identified 43 articles. Poor social relationships predicted cognitive decline; for structural (19 studies): pooled OR: 1.08 (95% CI: 1.05-1.11); functional (8 studies): pooled OR: 1.15 (95% CI: 1.00-1.32); and combined measures (7 studies): pooled OR: 1.12 (95% CI: 1.01-1.24). Meta-regression and subgroup analyses showed that the heterogeneity could be explained by the type of social relationship measurement and methodological quality of included studies. Despite heterogeneity in study design and measures, our meta-analyses show that multiple aspects of social relationships are associated with cognitive decline. As evidence for publication bias was found, the association might be overestimated and should therefore be interpreted with caution. Future studies are needed to better define the mechanisms underlying these associations. Potential causality of this prognostic association should be examined in future randomized controlled studies. © The Author 2016; all rights reserved. Published by Oxford University Press on behalf of the International Epidemiological Association.

A longitudinal study of interpersonal relationships among lesbian, gay, and bisexual adolescents and young adults: Mediational pathways from attachment to romantic relationship quality

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Starks, Tyrel J.; Newcomb, Michael E.; Mustanski, Brian

2016-01-01

The current study examined the potential for mental health to mediate associations between earlier attachment to parents and peers and later relationship adjustment during adolescence and young adulthood in a sample of sexual minority youth. Secondarily, the study examined associations between peer and parental attachment and relationship/dating milestones. Participants included 219 lesbian, gay, and bisexual youth who participated in six waves of data collection over 3.5 years. Parental attachment was associated with an older age of dating initiation, while peer attachment was associated with longer relationship length. Both peer and parental attachment were significantly associated with mental health in later adolescence and young adulthood. Mental health mediated the association between peer attachment and main partner relationship quality. While the total indirect effect of parental attachment on main partner relationship quality was statistically significant, specific indirect effects were not. Implications for the application of attachment theory and integration of interpersonal factors into mental health intervention with sexual minority youth are discussed. PMID:26108898

A Study on the Satisfaction of the Employees in the Internal Customer Relationship Management

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Yavuz Demirel

2008-06-01

Full Text Available In this study, the factors that affect the satisfaction of the workers in the Internal Customer Relationship Management (IntCRM in a X manufacturing-industry operation that has a leading role in the white-goods sector in Turkey are studied. In this context, the direction of the relationships among the dimensions of the Internal Customer Relationship Management (internal customer satisfaction, effective management, internal customer-focused culture and attitude, technological competence, cooperation and communication is examined. The study also deals with the relationship between the socio-demographic characteristics of the workers and internal customer satisfaction dimension, as well as the relationship between socio-demographic characteristics of the workers and cooperation/communication dimension in detail. Additionally, the question whether internal customer satisfaction level varies in accordance with the management style is settled. Besides, various suggestions for the internal customer satisfaction have been made, putting forward the factors that are effective in the internal customer (workers satisfaction

An Empirical Study of the Relationship Among Job Satisfaction, Organizational Commitment and Turnover Intention

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Sinem Aydogdu

2011-01-01

Full Text Available This study conducted on 100 employees from production sector and 82 employees from service provider sector. The relationship among job satisfaction, organizational commitment and turnover intention are investigated to determine statistically significant relations. The results of the study support the hypotheses. Job Satisfaction has a significant and positive relationship with three dimensions of organizational commitment and turnover intention has a significant and negative relationship with job satisfaction and organizational commitment.

Let it go: Relationship autonomy predicts pro-relationship responses to partner transgressions.

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Hadden, Benjamin W; Baker, Zachary G; Knee, C Raymond

2017-11-24

The purpose of the present research is to better understand how relationship autonomy-having more self-determined reasons for being committed to a relationship-contributes to pro-relationship responses to transgressions in romantic relationships (e.g., forgiveness and accommodation). Study 1 employed a cross-sectional design (N = 350) and Study 2 used a weekly diary (N = 121) to test associations between relationship autonomy and pro-relationship responses to transgressions. Studies 3 and 4 utilized dyadic designs (Study 3: N = 200 couples, 400 individuals; Study 4: N = 275 couples, 550 individuals) to determine how both partners' relationship autonomy is associated with pro-relationship responses. Results revealed that relationship autonomy is robustly associated with pro-relationship responses to transgressions, both as general tendencies and as responses to idiosyncratic transgressions. Results of actor-partner interdependence model (APIM) analyses in Studies 3 and 4 provide evidence that one's partner's relationship autonomy is important for promoting pro-relationship responses as well. Study 4 also found that people perceive that partners respond better to transgressions if their partner is high in relationship autonomy. This research provides consistent and compelling evidence that the degree of self-determination underlying commitment is important for understanding how people respond to transgressions in their relationships, beyond their current levels of commitment. © 2017 Wiley Periodicals, Inc.

Open, trusting relationships underpin safety in rural maternity a hermeneutic phenomenology study.

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Crowther, Susan; Smythe, Elizabeth

2016-11-24

There are interwoven personal, professional and organisational relationships to be navigated in maternity in all regions. In rural regions relationships are integral to safe maternity care. Yet there is a paucity of research on how relationships influence safety and nurture satisfying experiences for rural maternity care providers and mothers and families in these regions. This paper draws attention to how these relationships matter. This research is informed by hermeneutic phenomenology drawing on Heidegger and Gadamer. Thirteen participants were recruited via purposeful sampling and asked to share their experiences of rural maternity care in recorded unstructured in-depth interviews. Participants were women and health care providers living and working in rural regions. Recordings were transcribed and data interpretively analysed until a plausible and trustworthy thematic pattern emerged. Throughout the data the relational nature of rural living surfaced as an interweaving tapestry of connectivity. Relationships in rural maternity are revealed in myriad ways: for some optimal relationships, for others feeling isolated, living with discord and professional disharmony. Professional misunderstandings undermine relationships. Rural maternity can become unsustainable and unsettling when relationships break down leading to unsafeness. This study reveals how relationships are an important and vital aspect to the lived-experience of rural maternity care. Relationships are founded on mutual understanding and attuned to trust matter. These relationships are forged over time and keep childbirth safe and enable maternity care providers to work sustainably. Yet hidden unspoken pre-understandings of individuals and groups build tension in relationships leading to discord. Trust builds healthy rural communities of practice within which everyone can flourish, feel accepted, supported and safe. This is facilitated by collaborative learning activities and open respectful

Structure–kinetic relationship study of CDK8/CycC specific compounds

Science.gov (United States)

Schneider, Elisabeth V.; Böttcher, Jark; Huber, Robert; Maskos, Klaus; Neumann, Lars

2013-01-01

In contrast with the very well explored concept of structure–activity relationship, similar studies are missing for the dependency between binding kinetics and compound structure of a protein ligand complex, the structure–kinetic relationship. Here, we present a structure–kinetic relationship study of the cyclin-dependent kinase 8 (CDK8)/cyclin C (CycC) complex. The scaffold moiety of the compounds is anchored in the kinase deep pocket and extended with diverse functional groups toward the hinge region and the front pocket. These variations can cause the compounds to change from fast to slow binding kinetics, resulting in an improved residence time. The flip of the DFG motif (“DMG” in CDK8) to the inactive DFG-out conformation appears to have relatively little influence on the velocity of binding. Hydrogen bonding with the kinase hinge region contributes to the residence time but has less impact than hydrophobic complementarities within the kinase front pocket. PMID:23630251

Healing Relationships: A Qualitative Study of Healers and Their Clients in Germany

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B. M. H. Stöckigt

2015-01-01

Full Text Available Background. The aim of this study was to investigate the nature of the relationships between healers and their clients in Germany. Methods. An interdisciplinary research team performed semistructured interviews with healers and clients and participatory observation of healing sessions. All interviews were digitally recorded, transcribed, and analyzed using content analysis. Results. Fifteen healers and sixteen clients were included. The healer-client relationship was described as a profound and unique experience, which brought forth interpersonal and spiritual connections. The healers were seen as role models for healing to occur and support for being connected spiritually. The clients had to be open-minded and responsible. The importance of the healers’ empathy was emphasized. Discussion. The relationship between healer and client can be seen as a triangular connection between client, healer, and a transcendent source which is not the case in typical patient-doctor relationships. The spiritual connection is also said to enhance the empathetic understanding of the healer. The personality and a partner-like attitude of the healer supported the client in giving a more positive meaning to his life, in reconnecting to his spirituality, and in taking responsibility. Future studies should address the role of spirituality in health care and the development of enduring healer-client relationships.

A study of the relationship between health awareness, lifestyle ...

African Journals Online (AJOL)

Background: The objectives of the study were to determine whether consumers who read food labels, were also more aware of health and lifestyle issues, in terms of nutrition and other health-related lifestyle behaviours, and whether there was a relationship between food-label reading, health awareness and lifestyle ...

Exploring Familial Relationship Growth and Negotiation: A Case Study of Outward Bound Family Courses

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Overholt, Jillisa R.

2013-01-01

This study explored the phenomenon of father-child relationship development within the context of an Outward Bound (OB) family course, an environment that may both disrupt the ordinary aspects of an established relationship, and provide activities to purposefully encourage relationship development through a variety of aspects inherent to the…

Quality of Sibling Relationship and Substance Misuse: A Comparative Study

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Anastasia Tsamparli

2016-03-01

Full Text Available The aim of the current study is to examine the quality of sibling relationship in families with a sibling with substance misuse (SSU and compare the relationship to families with a sibling with no use (SNU. Thirty-six (36 families participated in the study (17 with SSU and 19 with SNU; N = 144. Semi-structured interviews were conducted with 40 siblings (20 SNU and 20 SSU; 18-31 years old in order to qualitatively investigate the characteristics of the sibling relationship. The siblings were not identified with any psychopathology, according to SCL-90R. Moreover, we considered the family cohesion and adaptability, as identified by the FACES III (administered to the whole sample and the family constellation (including number of children, birth order, gender, family size, family structure, years of substance misuse and socioeconomic level. The results of the thematic analysis seem to support Furman and Buhrmester’s (1985 framework, in the context of SNU families. Nevertheless, when considering families with SSU the framework is enriched with a new axis: Loss/mourning. The substance misuse seems to provoke an overturn of the representation of the sibling relationship: the behavioral changes (i.e. disengagement of the sibling with drug use are experienced as a loss by the sibling non user, thus triggering the psychological process of ‘mourning’. Moreover, in these families, the sibling with no drug use seem to experience differential parenting, they feel neglected, angry and they take up a parental role towards the SSU, whom they experience as “sensitive” and “vulnerable”.

A qualitative study of attachment relationships in ASD during middle childhood.

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Keenan, Belinda M; Newman, Louise K; Gray, Kylie M; Rinehart, Nicole J

2017-02-01

Although research has indicated that children with Autism Spectrum Disorder (ASD) display normative attachment behaviours, to date there has been limited qualitative research exploring these relationships. This study aimed to describe qualitative features of the child-caregiver attachment relationship in children with ASD. Primary caregivers to 26 children with ASD (aged 7-14 years) and 23 typically developing children (aged 7-13 years) were administered the Disturbances of Attachment Interview (Smyke & Zeanah, 1999) to elicit descriptions of children's attachment behaviours. Thematic analysis of interview transcripts indicated that while children with ASD demonstrated a range of normative attachment behaviours, they displayed impairments in the use of the caregiver as a secure base and co-regulating agent. ASD-associated impairments in emotion processing, sharing/reciprocity, and emotion co-regulation, as well as the caregiver's experience, were important in understanding attachment relationships in ASD. Findings highlight the need to consider the bidirectional nature of the attachment relationship in ASD.

Relationship Maintenance on Facebook: Development of a Measure, Relationship to General Maintenance, and Relationship Satisfaction

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Dainton, Marianne

2013-01-01

Previous research indicates that the primary reason college students use Facebook is for relationship maintenance. The present study sought to determine the relationship between Facebook maintenance and general maintenance efforts in college student romantic relationships, as well as the impacts of such behaviors on the relationship. Survey data…

Caregiver Self-Esteem as a Predictor of Patient Relationship Satisfaction: A Longitudinal Study.

Science.gov (United States)

Mroz, Emily L; Poulin, Michael J; Grant, Pei C; Depner, Rachel M; Breier, Jennifer; Byrwa, David J; Wright, Scott T

2018-03-01

Longitudinal assessment of patient-caregiver relationships will determine whether caregiver self-esteem determines patient relationship satisfaction at end of life. Research on close relationships and caregiving supports the idea that informal caregivers' self-esteem may influence their relationships with their terminally ill loved ones. However, this connection has not yet been investigated longitudinally, nor has it been applied specifically to care recipients' relationship satisfaction. A sample of 24 caregivers and 24 patients in a hospice home care program were recruited. Multiple patient and caregiver interviews were used to conduct a longitudinal study to measure fluctuations in patient health, changes in patient and caregiver relationship satisfaction, and self-esteem over a three-month period. An interaction between caregiver self-esteem and patient relationship satisfaction demonstrated the role that self-esteem plays between caregivers and patients enrolled in hospice care. Specifically, for patients with caregivers with low self-esteem, patient relationship satisfaction significantly decreased as the patient's physical health decreased, whereas for patients whose caregivers had high self-esteem, patient relationship satisfaction marginally increased during poorer physical health. High self-esteem may allow caregivers to overcome feelings of burden and maladaptive anticipatory grief to remain satisfied in their relationship with the patient. Caregiver self-esteem appears to play a role in fostering patient relationship satisfaction at the end of life.

Topics on study of low dose-effect relationship

Energy Technology Data Exchange (ETDEWEB)

Yamada, Takeshi [Toho Univ., School of Medicine, Tokyo (Japan); Ohyama, Harumi

1999-09-01

It is not exceptional but usually observed that a dose-effect relationship in biosystem is not linear. Sometimes, the low dose-effect relationship appears entirely contrary to the expectation from high dose-effect. This is called a 'hormesis' phenomena. A high dose irradiation inflicts certainly an injury on biosystem. No matter how low the dose may be, an irradiation might inflict some injury on biosystem according to Linear Non-Threshold hypothesis(LNT). On the contrary to the expectation, a low dose irradiation stimulates immune system, and promotes cell proliferation. This is called 'radiation hormesis'. The studies of the radiation hormesis are made on from four points of view as follows: (1) radiation adaptive response, (2) revitalization caused by a low dose stimulation, (3) a low dose response unexpected from the LNT hypothesis, (4) negation of the LNT hypothesis. The various empirical proofs of radiation hormesis are introduced in the report. (M . Suetake)

Topics on study of low dose-effect relationship

International Nuclear Information System (INIS)

Yamada, Takeshi; Ohyama, Harumi

1999-01-01

It is not exceptional but usually observed that a dose-effect relationship in biosystem is not linear. Sometimes, the low dose-effect relationship appears entirely contrary to the expectation from high dose-effect. This is called a 'hormesis' phenomena. A high dose irradiation inflicts certainly an injury on biosystem. No matter how low the dose may be, an irradiation might inflict some injury on biosystem according to Linear Non-Threshold hypothesis(LNT). On the contrary to the expectation, a low dose irradiation stimulates immune system, and promotes cell proliferation. This is called 'radiation hormesis'. The studies of the radiation hormesis are made on from four points of view as follows: (1) radiation adaptive response, (2) revitalization caused by a low dose stimulation, (3) a low dose response unexpected from the LNT hypothesis, (4) negation of the LNT hypothesis. The various empirical proofs of radiation hormesis are introduced in the report. (M . Suetake)

3-alkyl fentanyl analogues: Structure-activity-relationship study

OpenAIRE

Vučković, Sonja; Savić-Vujović, Katarina; Srebro, Dragana; Ivanović, Milovan; Došen-Mićović, Ljiljana; Stojanović, Radan; Prostran, Milica

2012-01-01

Introduction. Fentanyl belongs to 4-anilidopiperidine class of synthetic opioid analgesics. It is characterized by high potency, rapid onset and short duration of action. A large number of fentanyl analogues have been synthesized so far, both to establish the structure-activity-relationship (SAR) and to find novel, clinically useful analgesic drugs. Objective. In this study, newly synthesized 3-alkyl fentanyl analogues were examined for analgesic activity and compared with fentanyl. Methods. ...

Relationship Enhancement Therapy: A Case Study for Treating Vaginismus.

Science.gov (United States)

Harman, Marsha J.; And Others

1994-01-01

A case study of Relationship Enhancement (RE) therapy with a couple, in which the woman was identified as having vaginismus, is presented including excerpts of transcripts from the therapy sessions. RE's effectiveness at improving communication skills and providing structure in which the couple could discuss the intimate issues affecting the…

A study on relationship between abnormal accruals and future profitability: Evidence from Tehran Stock Exchange

Directory of Open Access Journals (Sweden)

Mohammad Khodaei Valahzaghard

2013-11-01

Full Text Available This paper presents an empirical investigation to study the relationship between future profitability and abnormal accruals on selected firms from Tehran Stock Exchange (TSE. The study selects 223 firms from TSE market over the period 2007-2011. Using the regression analysis, the study shows there was no meaningful relationship between abnormal earnings and future profitability when the level of significance is five percent. There are also seven sub-hypotheses associated with the proposed study of this paper. The results indicate that while there were no meaningful relationship between firm size, ratio of book value to equity, capital expenditure, earnings quality, earning forecasted error and book value leverage on one side and future earnings, the study confirms a significance relationship between market leverage and future earnings.

A study on relationship between quality of life and employee performance

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Marziyeh Pourbagher

2014-08-01

Full Text Available This paper studies the relationship between quality of life and its eight components with employee performance in general directorate of youth and sport in province of Golestan, Iran. The study uses a questionnaire developed by Walton (1974 [Walton, R. E. (1974. Improving quality of work life. Harvard Business Review, 52(3, 12.] for quality of life and a standard questionnaire named ACHIEVE consists of 25 questions for measuring the performance. Using Spearman correlation test, the study has determined a positive and meaningful relationship between employee performance and eight components of Walton’s model including adequate and fair compensation, safe and healthy working conditions, development of human competencies, growth and security, social integration, constitutionalization and total life space and social reliance.

A study on relationship between internal auditing and quality of financial statement

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Maryam Abulghasemi Komeleh

2014-09-01

Full Text Available The primary objective of most financial statements is to provide a concentrated as well as categorized reports on financial performance and flexibility to help decision makers reach suitable financial decisions. This paper presents an empirical investigation to study the relationship between internal auditing and quality of financial statements on selected firms listed on Tehran Stock Exchange. The proposed study selects 140 firms over the period 2008-2012. Using some regression technique, the study has determined that there was a positive and meaningful relationship between firms with internal auditing in their activities and quality of financial statements.

Maternal Relationship, Social Skills and Parental Behavior Through Neuroimaging Techniques and Behavioral Studies

OpenAIRE

Serra, Mauro

2015-01-01

Mother child relationship is the first and the most important social relationship as it has implications on psychological and neural development of the individual. Here we investigated mother child relationship focusing on different aspects and using a combination of behavioural and neuroimaging techniques. In the first study we addressed the association between brain connectivity and interpersonal competences which are at the basis of every social interaction including the ones involved in m...

The Relationships of Problem Solving Styles to Parenting Styles: Two Studies

Science.gov (United States)

Neyen, Julia; Volpe, Carolyn Ann; Selby, Edwin C.; Houtz, John C.

2017-01-01

Two independent studies were conducted to examine the relationship of problem solving styles to parenting styles. Both studies used VIEW: An Assessment of Problem Solving Style and the Parental Authority Questionnaire (PAQ). Study 1 included 173 adults recruited using Mechanical Turk and Study 2 included 131 adults recruited using Qualtrics. Data…

Study of the CASAS Relationship to GED 2002. Research Brief

Science.gov (United States)

CASAS - Comprehensive Adult Student Assessment Systems (NJ1), 2003

2003-01-01

CASAS, in cooperation with the CASAS National Consortium Policy Council, conducted a study to provide guidance to program and instructional staff regarding student readiness to take the GED Tests. The study looked at the relationship of CASAS reading and math scores to official 2002 GED test results from five states--California, Hawaii, Iowa,…

The relationship between suicide and Islam: a cross-national study.

Science.gov (United States)

Shah, Ajit; Chandia, Mahmood

2010-06-01

Traditionally, suicide rates were low in Islamic countries. However, the process of modernization can erode the ties of the individual to society and lead to questioning of religion and weakening of faith. Therefore, a cross-national study with the null hypothesis that there will be no relationship between general population suicide rates and the percentage of adherents of Islam was undertaken. The correlation between general population suicide rates and the percentage of people in the general population adherent to Islam, whilst controlling for socioeconomic status and income inequality, was examined using cross-national data from the World Health Organization and the United Nations. There were significant negative correlations between general population suicide rate and the percentage of people adherent to Islam in males and females whilst controlling for socioeconomic status and income inequality. Caution should be exercised in attributing a causal relationship and the direction of causality from this ecological study due to ecological fallacy. However, there is case to study further the impact of Islam on suicide by in-depth study of adherents Islam with and without suicidal ideation and behaviors. ‎

A systematic review of dyadic studies examining relationship quality in couples facing colorectal cancer together.

Science.gov (United States)

Kayser, Karen; Acquati, Chiara; Reese, Jennifer Barsky; Mark, Kristen; Wittmann, Daniela; Karam, Eli

2018-01-01

Despite the adverse effects that treatment for colorectal cancer can have on patients' quality of life and, in particular, their intimate relationships, very little research has been conducted on the psychosocial adjustment for both patients and their partners/spouses. The aim of this systematic review was to examine dyadic studies of adjustment in couples in which one partner has been diagnosed with colorectal cancer. Pub Med, PsychINFO, MEDLINE, Social Sciences Abstracts (EBSCO), and the Cochrane Library were systematically searched for studies reporting quality of life outcomes for colorectal cancer patients and their partners/spouses. Only studies that included dyads in the sample were eligible for inclusion. The Quality Assessment Tool for Quantitative Studies was used to evaluate each study. A total of 277 studies were identified, of which 9 studies met the inclusion criteria (N = 388 couples). The methodological quality of the studies was high in that they used standardized instruments validated with their samples, conducted dyadic data analyses (when appropriate), and used longitudinal designs. A synthesis of the studies revealed that (1) relationship factors (eg, support, communication, dyadic coping, and relationship satisfaction) affect adjustment to cancer; (2) cancer-related distress impacts each partner's adjustment or the relationship; and (3) gender, role (patient/caregiver), and clinical characteristics (treatment, mental health) can mediate adjustment to cancer. The quality of the relationship can influence patients' and their partners' adjustment to colorectal cancer. Psychosocial interventions that address relationship issues may be beneficial to couples facing the challenges of colorectal cancer. Copyright © 2016 John Wiley & Sons, Ltd.

CUSTOMER RELATIONSHIP MANAGEMENT (CRM SUCCESS FACTORS: AN EXPLORATORY STUDY

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Mohammed ALAMGIR

2015-02-01

Full Text Available Customer relationship management (CRM can improve organization’s performance through applying customer knowledge and maintaining relationships with customers. Literature on CRM in an integrative fashion is sparse, rather issues are presented in isolation mostly focusing on technology ignoring other extra-organizational issues like social rapport and customer knowledge. Likewise, CRM success is poorly sketched and social rapport as a facilitator of knowledge generation has received little attention in the previous literature. Therefore, the main purpose of this research is to investigate the role of CRM, customer knowledge and social rapport on CRM success. The present study considers the Resource-based view in developing CRM success framework. A Qualitative research approach has been taken in this study where ten customer-service managers of different telecom operators of Bangladesh have been interviewed. To identify the factors along with their associated variables and also to further develop a research model a content analysis technique has been utilized. The results of the interviews identified three factors affecting CRM success. This paper also highlights the research and managerial implications of the model.  

The influence of social relationships on obesity: sex differences in a longitudinal study.

Science.gov (United States)

Oliveira, Aldair J; Rostila, Mikael; de Leon, Antônio P; Lopes, Claudia S

2013-08-01

To investigate the effect of five dimensions of social relationships on obesity and potential sex differences in these associations. This study used longitudinal data from the Swedish Level of Living Surveys (LNU) in 1991 and 2000. The sample included 3,586 individuals. The dimensions of social relationships examined in this study include emotional support, frequency of visiting friends, marital status, marital status changes, and a Social Relationships Index (SRI). Obesity status was based on BMI (kg/m(2)) and calculated with self-reported measurements. The association between social relationships and the incidence of obesity after 9 years of follow-up was evaluated through Poisson regressions. After controlling for confounders, we found that the lack of emotional support (RR = 1.98; 95% CI, 1.1-4.6) influenced the incidence of obesity among men. In addition, men with the lowest levels of SRI (RR = 2.22; 95% CI, 1.1-4.4) had an increased risk of being obese. Among women, SRI was not significantly associated with obesity. Women who changed their marital status from married to unmarried had lower risk of obesity (RR = 0.39; 95% CI, 0.2-0.9). This study provides evidence for the effect of social relationships on the incidence of obesity, with significant differences by sex. Copyright © 2013 The Obesity Society.

Structure-activity relationship studies of citalopram derivatives

DEFF Research Database (Denmark)

Larsen, M Andreas B; Plenge, Per; Andersen, Jacob

2016-01-01

towards the S2 site. EXPERIMENTAL APPROACH: We performed a systematic structure-activity relationship study based on the scaffold of citalopram and the structurally closely related congener, talopram, that shows low-affinity S1 binding in SERT. The role of the four chemical substituents, which distinguish...... citalopram from talopram in conferring selectivity towards the S1 and S2 site, respectively, was assessed by determining the binding of 14 citalopram/talopram analogous to the S1 and S2 binding sites in SERT using membranes of COS7 cells transiently expressing SERT. KEY RESULTS: The structure-activity...

Externally predictive single-descriptor based QSPRs for physico-chemical properties of polychlorinated-naphthalenes: Exploring relationships of log SW, log KOA, and log KOW with electron-correlation

International Nuclear Information System (INIS)

Chayawan; Vikas

2015-01-01

Highlights: • Aqueous solubility and partition coefficient are modelled using single-parameter. • Electron-correlation observed as a vital predictorof physico-chemical properties. • For octanol-air partition coefficient, energy and polarizability yield best models. • Dipole-moment is found to be worst single-descriptor for the properties analysed. - Abstract: Quantitative structure–property relationships (QSPRs), based only on a single-parameter, are proposed for the prediction of physico-chemical properties, namely, aqueous solubility (log S W ), octanol–water partition coefficient (log K OW ) and octanol–air partition coefficient (log K OA ) of polychloronaphthalenes (PCNs) including all the 75 chloronaphthalene congeners. The QSPR models are developed using molecular descriptors computed through quantum mechanical methods including ab-initio as well as advanced semi-empirical methods. The predictivity of the developed models is tested through state-of-the-art external validation procedures employing an external prediction set of compounds. To analyse the role of instantaneous interactions between electrons (the electron-correlation), the models are also compared with those developed using only the electron-correlation contribution of the quantum chemical descriptor. The electron-correlation contribution towards the chemical hardness and the LUMO energy are observed to be the best predictors for octanol–water partition coefficient, whereas for the octanol–air partition coefficient, the total electronic energy and electron-correlation energy are found to be reliable descriptors, in fact, even better than the polarisability. For aqueous solubility of PCNs, the absolute electronegativity is observed to be the best predictor. This work suggests that the electron-correlation contribution of a quantum-chemical descriptor can be used as a reliable indicator for physico-chemical properties, particularly the partition coefficients

Headquarters Air Force Material Command Customer Relationship Study

Science.gov (United States)

2006-03-01

Abstract Because of the lack of product and price differentiation, many organizations consider Customer Relationship Management ( CRM ) their...8 Customer Relationship Management ……………………………………………....11 Benefits of CRM …………………………………………………………………...17...consider Customer Relationship Management ( CRM ) their primary focus – a focus that attempts to maximize every sales opportunity and optimize every

Job Satisfaction and Teacher-Student Relationships across the Teaching Career: Four Case Studies

Science.gov (United States)

Veldman, Ietje; van Tartwijk, Jan; Brekelmans, Mieke; Wubbels, Theo

2013-01-01

We studied the development of teacher-student relationships and teachers' job satisfaction throughout the careers of four veteran teachers who retained high job satisfaction. Teacher data gathered with the narrative-biographical method were compared with students' perceptions of the teacher-student relationships, using the Questionnaire on Teacher…

Understanding Adolescent–Parent Interpersonal Relationships in Youth Sports: A Mixed-Methods Study

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Ausra Lisinskiene

2018-05-01

Full Text Available The purpose of this study was to examine the relationship between participation in youth sport and adolescent–parent attachment. A mixed-method explanatory sequential study design was applied. In the first phase, 648 adolescent athletes and non-athletes completed the Inventory of Parent and Peer Attachment–Revised (IPPA–R. In the second phase, 15 adolescent athletes took part in semi-structured interviews. In the first, quantitative phase, three factors were predictors of adolescents’ attachment to parents and peers: trust, communication, and alienation. In the qualitative follow-up, three themes emerged: adolescents’ attachment to the sport; adolescent–parent attachment; adolescents’ thoughts about parents. The analysis of the adolescent–parent interpersonal relationship revealed that athlete adolescents’ relations and attachment to parents compared to non-athlete adolescents are more intensively expressed in all scales: trust, communication and alienation. Interviews with adolescent athletes revealed that parent–adolescent interpersonal relationship and attachment to parents is more important at the early period of sporting life, and becomes less appreciable or unwelcome when children gain sporting experience. The study indicated that the form and degree of parental involvement in children’s sporting activities impacts the effectiveness of parent–athlete interpersonal relationships. The degree and the form of parental involvement in children’s sports chosen by the parents are not always appropriate and encouraging, and they are not always supportive of adolescents’ opinions.

Establishing supervisor-students’ relationships through mutual expectation: A study from supervisors’ point of view

Science.gov (United States)

Masek, Alias

2017-08-01

The literature suggests that failure to establish a good relationship in communicating expectations of research supervision is one of the factors contributing to the slow pace of research progress. Moreover, it is not fully understood how students and a supervisor ‘pre-define’ their styles and communicate their expectations through a successful relationship. As a result, the students might lose motivation to do their research during the study period and are not able to complete their research on time. This will subsequently entail an extension of the study period. Without a good relationship between students and the supervisor, miscommunication occurs, leading to mismatched expectations from both parties. This research attempts to explore the establishment of a good supervisor-students’ relationship from supervisor point of views, so that supervision expectations can be clearly delivered and effectively communicated; guidelines will be drawn up for forging the supervisor-students’ relationship basing on mutual expectations of both parties.

A study on the relationship between incoming solar UV radiation and cloud cover

International Nuclear Information System (INIS)

Daoo, V.J.

1992-01-01

In this study an empirical relationship between the incoming solar UV radiation and concurrently measured cloud cover at Bombay (19 o 01'N, 72 o 55'E), based on data pertaining to two year (1986-1987) period is established. It is compared with a similar relationship used elsewhere and found to differ in its form as well as in the regression coefficients. Possible reasons for this discrepancy are discussed. Conditions under which the two relationships agree are also examined. (author)

What is the relationship between free flow and pressure flow studies in women?

Science.gov (United States)

Duckett, Jonathan; Cheema, Katherine; Patil, Avanti; Basu, Maya; Beale, Sian; Wise, Brian

2013-03-01

The relationship between free flow (FFS) and pressure flow (PFS) voiding studies remains uncertain and the effect of a urethral catheter on flow rates has not been determined. The relationship between residuals obtained at FF and PFS has yet to be established. This was a prospective cohort study based on 474 consecutive women undergoing cystometry using different sized urethral catheters at different centres. FFS and PFS data were compared for different conditions and the relationship of residuals analysed for FFS and PFS. The null hypothesis was that urethral catheters do not produce an alteration in maximum flow rates for PFS and FF studies. Urethral catheterisation results in lower flow rates (p flows are corrected for voided volume (p flow rates are lower in women with DO than USI (p flow rates and vice versa. There was no significant difference between the mean residuals of the two groups (FFS vs PFS-two-tailed t = 0.54, p = 0.59). Positive residuals in FFS showed a good association with positive residuals in the PFS (r = 0.53, p flow rates. The relationship can be compared mathematically. The null hypothesis can be rejected.

Relationship transitions and change in health behavior: A four-phase, twelve-year longitudinal study.

Science.gov (United States)

Josefsson, Kim; Elovainio, Marko; Stenholm, Sari; Kawachi, Ichiro; Kauppi, Maarit; Aalto, Ville; Kivimäki, Mika; Vahtera, Jussi

2018-03-19

Extensive scientific evidence shows an association between involvement in social relationships and healthy lifestyle. Prospective studies with many participants and long follow-ups are needed to study the dynamics and change in social factors within individuals over time. Our aim was to determine whether a change in relationship status (single, married, divorced, widow, cohabiting) is followed by a change in health behavior (smoking, alcohol consumption, physical activity, and body mass index). We used data from 81,925 healthy adults participating in the prospective longitudinal Finnish Public Sector Study in the period 2000-2013. We analyzed 327,700 person-observations from four data collection phases. Missing data were multiply imputed. A within-individual methodology was used to minimize the possibility of selection effects affecting the interpretation. All four health behaviors showed associations with relationship status. The effects were very similar and in the same direction in women and men, although there were gender differences in the magnitudes of the effects. The end of a relationship was followed by a decrease in body mass index, increased odds of being a smoker, increase in physical activity, and increase in alcohol consumption (widowed men). The effects were reverse when forming a new relationship. A change in relationship status is associated with a change in health behavior. The association is not explained by socioeconomic status, subjective health status, or anxiety level. People leaving or losing a relationship are at increased risk of unhealthy behavior (smoking and alcohol consumption), but at the same time they have a lower BMI and show higher physical activity compared to the time they were in a relationship. It is not clear if the cumulative health effect of these health behavior changes is positive or negative. Copyright © 2018 Elsevier Ltd. All rights reserved.

Qualitative Study of Relationship With God in Old Age

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Abdolah Motamedi

2017-06-01

Conclusion The final model suggests a wide variation in relation to the quality and quantity of relationship with God. The role of the emotional, cognitive, and social factors in the emergence of this behavior (relationship with God was clear and in accordance with the mediator conditions and the perceived consequences of the relationship.

An Empirical Study to Determine The Relationship between Occupational Self-Efficacy and Organizational Silence

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Cem KAHYA

2015-06-01

Full Text Available The concept of occupational self-efficacy means the efficacy perceptions of employees in their occupational fields, and the concept of organizational silence means the employees avoid to voice their ideas and suggestions about organizational issues. The main aim of this study is to examine the relationship between the concepts of occupational self-efficacy and organizational silence by revealing employees’ perceptions of occupational self-efficacy and organizational silence level. With this aim, the survey study was conducted on total 114 academicians who work in University of Bayburt. As a result of research, while the significant relationship was found between employees’ perceptions of occupational self-efficacy and organizational silence level, there was reached a result that this relationship incurred the negatively relationship between perceptions of occupational self-efficacy and negative silence.

Soil erosion-runoff relationships: insights from laboratory studies

Science.gov (United States)

Mamedov, Amrakh; Warrington, David; Levy, Guy

2016-04-01

Understanding the processes and mechanisms affecting runoff generation and subsequent soil erosion in semi-arid regions is essential for the development of improved soil and water conservation management practices. Using a drip type laboratory rain simulator, we studied runoff and soil erosion, and the relationships between them, in 60 semi-arid region soils varying in their intrinsic properties (e.g., texture, organic matter) under differing extrinsic conditions (e.g., rain properties, and conditions prevailing in the field soil). Both runoff and soil erosion were significantly affected by the intrinsic soil and rain properties, and soil conditions within agricultural fields or watersheds. The relationship between soil erosion and runoff was stronger when the rain kinetic energy was higher rather than lower, and could be expressed either as a linear or exponential function. Linear functions applied to certain limited cases associated with conditions that enhanced soil structure stability, (e.g., slow wetting, amending with soil stabilizers, minimum tillage in clay soils, and short duration exposure to rain). Exponential functions applied to most of the cases under conditions that tended to harm soil stability (e.g., fast wetting of soils, a wide range of antecedent soil water contents and rain kinetic energies, conventional tillage, following biosolid applications, irrigation with water of poor quality, consecutive rain simulations). The established relationships between runoff and soil erosion contributed to a better understanding of the mechanisms governing overland flow and soil loss, and could assist in (i) further development of soil erosion models and research techniques, and (ii) the design of more suitable management practices for soil and water conservation.

Intercultural challenges in offshore software development outsourcing relationship: an empirical study

International Nuclear Information System (INIS)

Khan, S.U.; Azeem, M.I.

2016-01-01

The importance of intercultural challenges is recognized by both the practitioners and researchers in offshore software development outsourcing (OSDO) relationships. These challenges affect almost all the activities involved in offshore software development outsourcing relationships especially communication, mutual understanding, interpretation and decision making processes etc. which in turn leads to project failure. In our previous published study we identified, through systematic literature review (SLR), various intercultural challenges faced by vendors in OSDO relationship. The aim of this study was to validate these findings through industry practitioners and to identify its intensity as well as to identify any other intercultural challenges, faced by vendor organizations in OSDO relationships. We performed questionnaire surveys with 41 experts from different software companies. A seven point likert scale was used to determine the significance of each intercultural challenge. Our findings indicate that all the intercultural challenges are critical for OSDO vendors. We further analyzed these challenges based on different variables, such as company size, company type, expert's job/position etc. We have identified that there is no significant difference in the intercultural challenges based on company type and expert's experience level. We identified that language and language proficiency is the most commonly agreed and difference in social behavior is the most commonly disagreed intercultural challenge in the category of both sizes of company. Similarly language and language proficiency is the most commonly agreed challenge based on experts job positions. (author)

Study the Relationship between Pavement Surface Distress and Roughness Data

Directory of Open Access Journals (Sweden)

Mubaraki Muhammad

2016-01-01

Full Text Available In this paper, pavement sections from the highway connected Jeddah to Jazan were selected and analyzed to investigate the relationship between International Roughness Index (IRI and pavement damage including; cracking, rutting, and raveling. The Ministry of Transport (MOT of Saudi Arabia has been collecting pavement condition data using the Road Surface Tester (RST vehicle. The MOT measures Roughness, Rutting (RUT, Cracking (CRA, raveling (RAV. Roughness measurements are calculated in terms of the International Roughness Index (IRI. The IRI is calculated over equally spaced intervals along the road profile. Roughness measurements are performed at speed between at 80 kilometers per hour. Thus RST vehicle has been used to evaluate highways across the country. The paper shows three relationships including; cracking (CRA verses roughness (IRI, rutting (RUT verses IRI, and raveling (RAV verses IRI. Also, the paper developed two models namely; model relates IRI to the three distress under study, and model relates IRI to ride quality. The results of the analysis claim at 95% confidence that a significant relationship exist between IRI and cracking, and raveling. It’s also shown that rutting did not show significant relationship to IRI values. That’s leads to conclude that the distresses types: cracking and raveling may possibly be described as ride quality distresses at different level of significant. Rutting distress described as non-ride quality type’s distresses.

A Study of the Relationship Between School Leadership and the Condition of School Buildings

OpenAIRE

Brannon, William Lee

2000-01-01

The purpose of this study was to examine the relationship between school leadership and the quality, condition, maintenance, improvements, and renovations of public school buildings. The first question examined the relationship between building conditions and perceptions of school board members, superintendent and central office staff, board of supervisors, and principals. The second question examined the relationship between building conditions and the financial support of leadership positio...

Prediction of ferric iron precipitation in bioleaching process using partial least squares and artificial neural network

Directory of Open Access Journals (Sweden)

Golmohammadi Hassan

2013-01-01

Full Text Available A quantitative structure-property relationship (QSPR study based on partial least squares (PLS and artificial neural network (ANN was developed for the prediction of ferric iron precipitation in bioleaching process. The leaching temperature, initial pH, oxidation/reduction potential (ORP, ferrous concentration and particle size of ore were used as inputs to the network. The output of the model was ferric iron precipitation. The optimal condition of the neural network was obtained by adjusting various parameters by trial-and-error. After optimization and training of the network according to back-propagation algorithm, a 5-5-1 neural network was generated for prediction of ferric iron precipitation. The root mean square error for the neural network calculated ferric iron precipitation for training, prediction and validation set are 32.860, 40.739 and 35.890, respectively, which are smaller than those obtained by PLS model (180.972, 165.047 and 149.950, respectively. Results obtained reveal the reliability and good predictivity of neural network model for the prediction of ferric iron precipitation in bioleaching process.

Performance of Deep and Shallow Neural Networks, the Universal Approximation Theorem, Activity Cliffs, and QSAR.

Science.gov (United States)

Winkler, David A; Le, Tu C

2017-01-01

Neural networks have generated valuable Quantitative Structure-Activity/Property Relationships (QSAR/QSPR) models for a wide variety of small molecules and materials properties. They have grown in sophistication and many of their initial problems have been overcome by modern mathematical techniques. QSAR studies have almost always used so-called "shallow" neural networks in which there is a single hidden layer between the input and output layers. Recently, a new and potentially paradigm-shifting type of neural network based on Deep Learning has appeared. Deep learning methods have generated impressive improvements in image and voice recognition, and are now being applied to QSAR and QSAR modelling. This paper describes the differences in approach between deep and shallow neural networks, compares their abilities to predict the properties of test sets for 15 large drug data sets (the kaggle set), discusses the results in terms of the Universal Approximation theorem for neural networks, and describes how DNN may ameliorate or remove troublesome "activity cliffs" in QSAR data sets. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Prediction of octanol-water partition coefficients of organic compounds by multiple linear regression, partial least squares, and artificial neural network.

Science.gov (United States)

Golmohammadi, Hassan

2009-11-30

A quantitative structure-property relationship (QSPR) study was performed to develop models those relate the structure of 141 organic compounds to their octanol-water partition coefficients (log P(o/w)). A genetic algorithm was applied as a variable selection tool. Modeling of log P(o/w) of these compounds as a function of theoretically derived descriptors was established by multiple linear regression (MLR), partial least squares (PLS), and artificial neural network (ANN). The best selected descriptors that appear in the models are: atomic charge weighted partial positively charged surface area (PPSA-3), fractional atomic charge weighted partial positive surface area (FPSA-3), minimum atomic partial charge (Qmin), molecular volume (MV), total dipole moment of molecule (mu), maximum antibonding contribution of a molecule orbital in the molecule (MAC), and maximum free valency of a C atom in the molecule (MFV). The result obtained showed the ability of developed artificial neural network to prediction of partition coefficients of organic compounds. Also, the results revealed the superiority of ANN over the MLR and PLS models. Copyright 2009 Wiley Periodicals, Inc.

Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye.

Science.gov (United States)

Ramsay, Eva; Del Amo, Eva M; Toropainen, Elisa; Tengvall-Unadike, Unni; Ranta, Veli-Pekka; Urtti, Arto; Ruponen, Marika

2018-07-01

On the surface of the eye, both the cornea and conjunctiva are restricting ocular absorption of topically applied drugs, but barrier contributions of these two membranes have not been systemically compared. Herein, we studied permeability of 32 small molecular drug compounds across an isolated porcine cornea and built a quantitative structure-property relationship (QSPR) model for the permeability. Corneal drug permeability (data obtained for 25 drug molecules) showed a 52-fold range in permeability (0.09-4.70 × 10 -6  cm/s) and the most important molecular descriptors in predicting the permeability were hydrogen bond donor, polar surface area and halogen ratio. Corneal permeability values were compared to their conjunctival drug permeability values. Ocular drug bioavailability and systemic absorption via conjunctiva were predicted for this drug set with pharmacokinetic calculations. Drug bioavailability in the aqueous humour was simulated to be drug across the conjunctiva to the blood circulation restricts significantly ocular drug bioavailability and, therefore, ocular absorption does not increase proportionally with the increasing corneal drug permeability. Copyright © 2018 Elsevier B.V. All rights reserved.

Antecedents and outcomes of satisfaction in buyer–supplier relationships in South Africa: A replication study

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Mornay Roberts-Lombard

2017-10-01

Full Text Available Background: There is a clear difference of opinion amongst researchers on the interrelatedness of the variables trust, commitment, satisfaction, coordination, cooperation and continuity in a business-to-business (B2B environment. The reason is that in previous studies much emphasis has been placed on creating and testing new theories, and not on providing practical generalities. Aim: The aim of this study was to determine how the variable satisfaction is positioned in relation to trust and commitment, and how satisfaction relates to the variables coordination, cooperation and continuity in a South African B2B environment. Setting: This study replicates a similar study conducted in 2013 in a B2B environment in South Africa and hopes to validate the outcome of that study by determining the relationship between the constructs postulated in the current study. The relationships between the different constructs in the proposed model will, therefore, provide a longitudinal perspective which is unique in terms of B2B research in South Africa. Methods: Both the original and replication studies followed a quantitative approach and targeted large companies in South Africa. In the original study, data were collected from 500 large South African companies, while in the replication study data were collected from 250 large companies. Structural equation modelling was used to analyse the data. Results: The findings specifically point to the need for organisations to direct resources towards the establishment of relationships that are founded on trust and commitment. Doing so will help ensure increased satisfaction, which, in turn, will result in greater coordination and cooperation in B2B relationships as well as long-term continuation of the relationship. Conclusion: The foundation for strong B2B relationships is to secure customer satisfaction. Business managers ought to understand that when business customers are dissatisfied, it can result in the

FRANCHISOR-FRANCHISEE RELATIONSHIP QUALITY: TIME OF RELATIONSHIP AND PERFORMANCE

Directory of Open Access Journals (Sweden)

Luís Fernando Varotto

2016-11-01

Full Text Available Franchise literature disputes how the relationship between franchisors and franchisees develops over time. Traditional lifecycle theory views relationships following an ascendant curve, in which relationship quality and performance strengthen over time. Another perspective better reflects the peculiarities of the franchisor-franchisee relationship, indicating that relationship quality in franchise systems follows a U-shaped curve. There is also limited research on the moderating effect of time on the relationship between relational variables and outcomes. This study sheds light on the influence of relationship duration on relationship quality and financial performance in the franchisee-franchisor relationship. Using a self-report survey from a sample of 342 franchisees, mean and regression analyses are conducted to test relationships. Results confirm the time effect on franchisor-franchisee relationship quality and performance, but the hypothesized shape of relationship phases is only partially confirmed. Moreover, time has a positive moderating effect on the impact of relationship quality on financial performance.

Externally predictive quantitative modeling of supercooled liquid vapor pressure of polychlorinated-naphthalenes through electron-correlation based quantum-mechanical descriptors.

Science.gov (United States)

Vikas; Chayawan

2014-01-01

For predicting physico-chemical properties related to environmental fate of molecules, quantitative structure-property relationships (QSPRs) are valuable tools in environmental chemistry. For developing a QSPR, molecular descriptors computed through quantum-mechanical methods are generally employed. The accuracy of a quantum-mechanical method, however, rests on the amount of electron-correlation estimated by the method. In this work, single-descriptor QSPRs for supercooled liquid vapor pressure of chloronaphthalenes and polychlorinated-naphthalenes are developed using molecular descriptors based on the electron-correlation contribution of the quantum-mechanical descriptor. The quantum-mechanical descriptors for which the electron-correlation contribution is analyzed include total-energy, mean polarizability, dipole moment, frontier orbital (HOMO/LUMO) energy, and density-functional theory (DFT) based descriptors, namely, absolute electronegativity, chemical hardness, and electrophilicity index. A total of 40 single-descriptor QSPRs were developed using molecular descriptors computed with advanced semi-empirical (SE) methods, namely, RM1, PM7, and ab intio methods, namely, Hartree-Fock and DFT. The developed QSPRs are validated using state-of-the-art external validation procedures employing an external prediction set. From the comparison of external predictivity of the models, it is observed that the single-descriptor QSPRs developed using total energy and correlation energy are found to be far more robust and predictive than those developed using commonly employed descriptors such as HOMO/LUMO energy and dipole moment. The work proposes that if real external predictivity of a QSPR model is desired to be explored, particularly, in terms of intra-molecular interactions, correlation-energy serves as a more appropriate descriptor than the polarizability. However, for developing QSPRs, computationally inexpensive advanced SE methods such as PM7 can be more reliable than

Social relationships among adolescents as described in an electronic diary: a mixed methods study.

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Anttila, Katriina I; Anttila, Minna J; Kurki, Marjo H; Välimäki, Maritta A

2017-01-01

Social relationships among adolescents with mental disorders are demanding. Adolescents with depressive symptoms may have few relationships and have difficulties sharing their problems. Internet may offer reliable and easy to use tool to collect real-time information from adolescents. The aim of this study is to explore how adolescents describe their social relationships with an electronic diary. Mixed methods were used to obtain a broad picture of adolescents' social relationships with the data gathered from network maps and reflective texts written in an electronic diary. Adolescents who visited an outpatient clinic and used an intervention (N=70) designed for adolescents with signs of depression were invited to use the electronic diary; 29 did so. The quantitative data gathered in the electronic diary were summarized with descriptive statistics, and the qualitative data were categorized using a thematic analysis with an inductive approach. We found that social relationships among adolescents with signs of depression can vary greatly in regards to the number of existing relationships (from lacking to 21) and the quality of the relationships (from trustful to difficult). However, the relationships may change, and the adolescents are also willing to build up their social relationships. Professionals need to be aware of the diversity of adolescents' social relationships and their need for personalized support.

Relationship challenges and relationship maintenance activities following disclosure of transsexualism.

Science.gov (United States)

Alegría, C Aramburu

2010-12-01

• Transsexual persons are increasing their visibility in society, and health care providers and others (such as social workers) will be called upon to help with issues that transsexual persons face. Challenges that face transsexual persons often include issues involving relationships. Psychiatric and mental health nurses and other caregivers can increase their therapeutic skills in working with couples that include transsexual persons by becoming aware of these challenges and subsequent activities that can help with them. • This research study looks at couple relationships in which one partner reveals male-to-female transsexual identity. These are relationships that were established as man-woman and now will transition into relationships that include a male-to-female person and a female partner. • Common challenges for these couples include issues related to: (1) sexual identity and relationship uncertainty; (2) male-to-female transition decision making; and (3) presenting in public. • Relationship maintenance activities that helped the couples in the study maintain and strengthen their relationships through these challenges include: (1) communication; (2) self-talk (for example, putting the situation in perspective); (3) social networks; (4) positive interactions; (5) impression management (for example, managing displays of affection in public); and (6) social activism. This qualitative study describes the relational dynamics that help sustain relationships of couples that include male-to-female transsexual persons (MTF) and their natal female partners (NF) following disclosure of transsexualism. Relationship challenges and relationship maintenance activities are identified. Each partner in 17 MTF-NF couples participated in individual surveys and interviews. The data were coded for themes related to relationship challenges and activities. MTF-NF couples experience challenges within the contexts of their relationships and of society. These challenges

Remembering the Good Times: The Influence of Relationship Nostalgia on Relationship Satisfaction Across Time.

Science.gov (United States)

Mallory, Allen B; Spencer, Chelsea M; Kimmes, Jonathan G; Pollitt, Amanda M

2018-02-11

We conducted two studies to understand if reminiscing about early parts of a romantic relationship can increase positive affect and relationship satisfaction. In Study 1, we examined the psychometrics of an adapted relationship nostalgia measure, if relationship nostalgia changes positive affect, and if relationship nostalgia and relationship satisfaction are associated. In Study 2, we tested the longitudinal link between relationship nostalgia and relationship satisfaction. Rather than increasing positive affect, relationship nostalgia is associated with a movement toward emotional homeostasis. Additionally, relationship nostalgia is positively associated with relationship satisfaction at the same time point but in the short term, the association is negative-long term, this association disappears. Implications for using a relationship history in therapy are discussed. © 2018 American Association for Marriage and Family Therapy.

Relationship characteristics of women in interracial same-sex relationships.

Science.gov (United States)

Jeong, Jae Y; Horne, Sharon G

2009-01-01

The purpose of this study was to examine the relationship characteristics of women in interracial same-sex relationships with respect to their current level of stress, internalized homophobia, perceived relationship equality, relationship satisfaction, and social support. Four groups were compared according to their current type of race relationship (ethnic minority women with White partners, White partners only, both ethnic minority partners, and White women with ethnic minority partners). No significant differences were found in terms of children and income; however, ethnic minority women with ethnic minority partners reported lower education attainment than the other groups. Relationally, there were no significant differences by race relationship for social support, relationship equality, relationship satisfaction, or stress. Internalized homophobia was lowest for interracial partnerships (ethnic minority paired with White partner). These findings are discussed in relationship to minority stress.

Studying the Relationship between Organizational Innovation and System thought in Service Organization

OpenAIRE

Ali Margir; Nahid Tereh Eiduzehi; Zakaria Surizehi; Naser Kamaly Pur

2014-01-01

In this research, we study the relationship and effect of organizational innovation and its dimensions on system thought and the relationship between these two variables have been evaluated in better adaption process of service organizations with the environment and society. To collect data after defining validity and reliability, organizational innovation questionnaire of choopani & et al (2012) and system thought have been used the case statistical society includes all employees of water an...

Breaking Up Is Hard to Do: A Qualitative Interview Study of How and Why Youth Mentoring Relationships End

Science.gov (United States)

Spencer, Renée; Basualdo-Delmonico, Antoinette; Walsh, Jill; Drew, Alison L.

2017-01-01

Endings in youth mentoring relationships have received little empirical attention despite the fact that many relationships do end. The present study utilized qualitative interview data collected from participants in a longitudinal study of community-based mentoring relationships to examine how and why the relationships ended and how participants…

Trial and retribution: a qualitative study of whistleblowing and workplace relationships in nursing.

Science.gov (United States)

Jackson, Debra; Peters, Kathleen; Andrew, Sharon; Edenborough, Michel; Halcomb, Elizabeth; Luck, Lauretta; Salamonson, Yenna; Weaver, Roslyn; Wilkes, Lesley

2010-01-01

This paper reports a study aiming to present and describe the effects of whistleblowing episodes on nurses' workplace relationships. Eighteen participants with direct experience of whistleblowing were recruited into the study, which was informed by a qualitative narrative inquiry design. Findings were clustered into four main themes, namely: Leaving and returning to work-The staff don't like you; Spoiled collegial relationships-Barriers between me and my colleagues; Bullying and excluding-They've just closed ranks; and, Damaged inter-professional relationships-I did lose trust in doctors after that. Findings suggest a need to facilitate a climate in which it is safe for nurses (and others) to raise concerns about patient care or organisational wrongdoing, and to eliminate the existing belief that whistleblowing is a negative act fuelled by revenge or sedition.

Study on the relationship between Islamic leadership style, work ethics, job satisfaction, and employee performance

OpenAIRE

FEBRIANI RIZKI; THOYIB ARMANU; SURACHMAN S.; ROFIATY R.

2017-01-01

There are many studies to examine the relationship of Leadership Style, Work Ethic, Satisfaction and Employee Performance. However, these research more emphasis on study of non-Muslims. In addition, there is no study has comprehensively discussed the Leadership Style, Work Ethic, Satisfaction and Employee Performance. Therefore, this study will examine theoretically the relationship between Leadership Style, Work Ethic, Satisfaction and Employee Performance comprehensively and within Islamic ...

The relationship between elderly suicide rates and the internet: a cross-national study.

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Shah, Ajit

2010-05-01

Suicide rates generally increase with age. Internet websites and chat rooms have been reported both to promote suicides and to have a positive beneficial effect on suicidal individuals. The role of the internet in elderly suicides has not been studied. The relationship between elderly suicide rates and the prevalence of internet users was examined in a cross-national study using data from the World Health Organization and the United Nations website. The prevalence of internet users was significantly and positively correlated with suicide rates in both genders in the age bands 65-74 years and 75+ years. On multiple regression analysis the prevalence of internet users was independently associated with suicide rates in both genders in both age bands. Caution should be exercised in the attribution of a causal relationship and the direction of this relationship because of the cross-sectional and ecological study design whereby the findings are subject to ecological fallacy. However, the findings identify and support a need for further research.

Childhood sibling relationships as a predictor of major depression in adulthood: a 30-year prospective study.

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Waldinger, Robert J; Vaillant, George E; Orav, E John

2007-06-01

The authors examined the quality of sibling relationships in childhood as a predictor of major depression in adulthood. Study subjects were 229 men selected for mental and physical health and followed from ages 20 through 50 and beyond as part of a study of adult psychosocial development. Data were obtained from interviews with participants and their parents at intake and from follow-up interviews and self-report questionnaires completed by participants at regular intervals. These data were used to rate the quality of relationships with siblings, the quality of parenting received in childhood, and family history of depression as well as the occurrence, by age 50, of major depression, alcoholism, and use of mood-altering drugs (tranquilizers, sleeping pills, and stimulants). Poorer relationships with siblings prior to age 20 and a family history of depression independently predicted both the occurrence of major depression and the frequency of use of mood-altering drugs by age 50, even after adjustment for the quality of childhood relationships with parents. Poor relationships with parents in childhood did not predict the occurrence of depression by age 50 when family history of depression and the quality of relationships with siblings were taken into account. Quality of sibling relationships and family history of depression did not predict later alcohol abuse or dependence. Poor sibling relationships in childhood may be an important and specific predictor of major depression in adulthood. Further study of links between childhood sibling relationships and adult depression is warranted.

A Study of the Relationship Between Alcoholism and Character Disorder.

Science.gov (United States)

Wolfley, Virgil L.

Studies have shown that sociopaths and alcoholics tend to come from similar social backgrounds and that they share several characteristics. To investigate the relationship between alcoholism and character disorder syndrome in adult males, 20 males who had a history of alcohol problems and displayed characteristics of character disorder were…

A study on relationship between conflict management styles and organizational agility: A case study of Ilam state University, Iran

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Ardeshir Shiri

2014-01-01

Full Text Available The aim of present study is to explore the relationship between various styles of conflict management and organizational agility in Ilam state university. The study is quantitative one, having developmental orientation and comparative approach, which applies the strategy of survey research with an aim of exploration and description. It is implemented as single point and utilizes questionnaire as data collecting tool. The population and sample of the study include 425 and 205 individuals, respectively. The sample size is determined through Cochran’s formula and random sampling method has been used for sampling. In order to perform the data analysis, descriptive and inferential statistics as well as Spearman and Kendall test in SPSS were utilized. The results of the study reveal that there was a positive and significant relationship among four styles of conflict management (avoiding, forcing, compromising, and yielding, however there was no significant relationship between integrating conflict management and organizational agility.

The relationship between bicycle commuting and perceived stress: a cross-sectional study.

Science.gov (United States)

Avila-Palencia, Ione; de Nazelle, Audrey; Cole-Hunter, Tom; Donaire-Gonzalez, David; Jerrett, Michael; Rodriguez, Daniel A; Nieuwenhuijsen, Mark J

2017-06-23

Active commuting - walking and bicycling for travel to and/or from work or educational addresses - may facilitate daily, routine physical activity. Several studies have investigated the relationship between active commuting and commuting stress; however, there are no studies examining the relationship between solely bicycle commuting and perceived stress, or studies that account for environmental determinants of bicycle commuting and stress. The current study evaluated the relationship between bicycle commuting, among working or studying adults in a dense urban setting, and perceived stress. A cross-sectional study was performed with 788 adults who regularly travelled to work or study locations (excluding those who only commuted on foot) in Barcelona, Spain. Participants responded to a comprehensive telephone survey concerning their travel behaviour from June 2011 through to May 2012. Participants were categorised as either bicycle commuters or non-bicycle commuters, and (based on the Perceived Stress Scale, PSS-4) as either stressed or non-stressed. Multivariate Poisson regression with robust variance models of stress status based on exposures with bicycle commuting were estimated and adjusted for potential confounders. Bicycle commuters had significantly lower risk of being stressed than non-bicycle commuters (Relative Risk; RR (95% CI)=0.73 (0.60 to 0.89), p=0.001). Bicycle commuters who bicycled 4 days per week (RR (95% CI)=0.42 (0.24 to 0.73), p=0.002) and those who bicycled 5 or more days per week (RR (95% CI)=0.57 (0.42 to 0.77), pstressed than those who bicycled less than 4 days. This relationship remained statistically significant after adjusting for individual and environmental confounders and when using different cut-offs of perceived stress. Stress reduction may be an important consequence of routine bicycle use and should be considered by decision makers as another potential benefit of its promotion. © Article author(s) (or their employer

A study on relationship between organizational culture and organizational commitment

OpenAIRE

Maryam Khalili

2014-01-01

This paper presents an empirical investigation to study the relationship between organizational culture and organization commitment. The study uses two questionnaires, one for measuring organizational commitment originally developed by Meyer and Allen (1991) [Meyer, J. P., & Allen, N. J. (1991). A three-component conceptualization of organizational commitment. Human resource management review, 1(1), 61-89.] and the other one for organizational culture developed by Denison and Spreitzer (1991)...

Relationship Drivers in Provider - Consumer Relationships. Empirical Studies of Customer Loyalty Programs (första upplagan slutsåld / first edition sold out, 'print on demand' 60 €)

OpenAIRE

Arantola, Heli

2003-01-01

The study addressed a phenomenon that has become common marketing practice, customer loyalty programs. Although a common type of consumer relationship, there is limited knowledge of its nature. The purpose of the study was to create structured understanding of the nature of customer relationships from both the provider’s and the consumer’s viewpoints by studying relationship drivers and proposing the concept of relational motivation as a provider of a common framework for the analysis of thes...

Relationship outcomes as measurement criteria to assist communication strategists to manage organisational relationships

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E. Botha

2011-06-01

Full Text Available Nonfinancial assets like relationships are increasingly important to managers. Communication managers in particular are focusing on measuring and managing organisational relationships as a means to quantify the return on investment (ROI of public relations and communication strategies. Measuring relationships offers communication managers a way to evaluate its contribution to the organisation. A commonly agreed upon definition of these relationships, however, does not exist. If we consider communication management is a managerial function, it must first refine its instruments of measurement. This study looks at the three-stage model of organisational relationships (relationship antecedents, maintenance strategies and relationship outcomes proposed by Grunig & Huang (2000 to firstly review the development of the model. Secondly, the study takes an in-depth look at each relationship outcomes of trust, commitment, satisfaction and control mutuality. Lastly, we assess the reliability and validity of the use of current relationship outcome measures through a survey of 154 organisational relationships. Previous studies that have utilized these outcomes in the measurement of organisational relationships do not discuss the possible interaction (or relationship among these outcomes. This study contributes to current literature by both providing an improved framework for the measurement of relationship outcomes and hypothesizing about how these outcomes interact with one another. It also discusses the managerial implications of managing relationships through the constant measurement of trust, commitment, satisfaction and control mutuality

How nursing home residents develop relationships with peers and staff: a grounded theory study.

Science.gov (United States)

Roberts, Tonya; Bowers, Barbara

2015-01-01

Social support and social relationships have been repeatedly identified as essential to nursing home resident quality of life. However, little is known about ways residents develop relationships with peers or staff. This study was conducted to explore the ways resident develop relationships with peers and staff in nursing homes. Fifteen cognitively intact nursing home residents from two facilities were interviewed for this grounded theory study. Sampling, interviewing, and analysis occurred in a cyclical process with results at each stage of the study informing decisions about data collection and analysis in the next. Unstructured interviews and field observations were conducted. Data were analyzed with open, axial, and selective coding. Residents developed relationships with peers and staff largely as an unintended consequence of trying to have a life in the nursing home. Having a life was a two-step process. First, life motivations (Being Self and Creating a Positive Atmosphere) influenced resident preferences for daily activities and interaction goals and subsequently their strategies for achieving and establishing both. Second, the strategies residents used for achieving their required daily activities (Passing Time and Getting Needs Met) and interaction goals then influenced the nature of interaction and the subsequent peer or staff response to these interactions. Residents defined relationships as friendly or unfriendly depending on whether peers or staff responded positively or negatively. There was considerable overlap in the ways peer and staff relationships developed and the results highlight the role of peer and staff responsiveness in relationship development. The results provide possible explanations for the success of interventions in the literature designed to improve staff responsiveness to residents. The results suggest that adapting these kinds of interventions for use with peers may also be successful. The conceptual model also presents a number

A Study of the Relationship between Information Technology and Changes in Culture and Social Relationships

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Hosein Ebrahimabadi

2014-03-01

Full Text Available Information technology and its consequent virtual space are opening up a new sphere in psychological, sociological and cultural studies associated with the mutual effect of technology, culture and human beings in general, and the interaction of cyberspace and culture, identity and human relationships. Recent studies in this field should be examined at least to realize whether the psychological and social outcomes and the pathology of virtual spaces are the result of the overflow of problems and issues of society and the real space into virtual space, and to decide if the challenges and the social problems in question are due to the development and growth of electronic media and virtual space? While describing and explaining  the effect of culture, society and their consequent traditions on virtual spaces, relationships and their content, and examining the effect of virtual space on culture, social actions, identity, attitudes and individual and collective behavior, the present article stresses that considering the short history and the little experience of the interaction between human and information technology and virtual space, it seems too soon to speak decisively about the outcomes of information technology and virtual spaces. Therefore, two principles are suggested to be established in cultural and social research on cyberspace. First, in the study of virtual space, priorities should be identified correctly and one should not merely focus on the problems resulting from information and communication technology instead of dealing with fundamental issues. Second, both in the theoretical and the methodological aspects of studies on virtual space, in different social and cultural spheres, one cannot rely merely on traditional theories and method, and new methods, in terms of theory, methodology and tools, should be applied.

Student perceptions of stress, coping, relationships, and academic civility: a longitudinal study.

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Clark, Cynthia M; Nguyen, Danh T; Barbosa-Leiker, Celestina

2014-01-01

Academic incivility can increase student stress, jeopardize learning, damage relationships, and negatively impact the academic environment. This 3-year longitudinal study measured a cohort of prelicensure nursing students' progressive perceptions of stress, coping, student-student and faculty-student relationships, and levels of academic civility. While civility scores remained mild to moderately high overall, there was a slightly declining trend over the 3-year period. Perceived stressors and coping strategies and ways to improve academic civility are identified and discussed.

A Study of the Relationship Between Personality Characteristics and Ethical Sensitivity in Business.

Science.gov (United States)

1992-09-01

Functional Preferences. and Descriptions of the Sixteen Personality Tvyes ISTJ ISFJ INFJ INTJ ISTP ISFP INFP INTP ESTP ESFP ENFP ENTP ESTJ ESFJ ENFJ ENTJ...AD-A258 421lE li(( I U~~l E l iIi - -H AFIT/GCNMLSMI92S-9 A STUDY OF THE RELATIONSHIP BETWEEN PERSONALITY CHARACTERISTICS AND ETHICAL SENSITIVITY IN...Codes Avail and/or Dist Speot8.i AFIT/GCM/LSM/92S-9 A STUDY OF THE RELATIONSHIP BETWEEN PERSONALITY CHARACTERISTICS AND ETHICAL SENSITIVITY IN BUSINESS

Relationship Dissolution and Psychologically Aggressive Dating Relationships: Preliminary Findings From a College-Based Relationship Education Course.

Science.gov (United States)

Negash, Sesen; Cravens, Jaclyn D; Brown, Preston C; Fincham, Frank D

This study evaluated the impact of a relationship education program, delivered as part of a college course, among students (N = 152) who reported experiencing psychological aggression in their exclusive dating relationship. Preliminary results showed that compared to those in the control group, participants receiving relationship education were significantly more likely to end their romantic relationship, even after controlling for relationship satisfaction. Furthermore, when relationship termination occurred, those in the intervention group were significantly more likely to attribute the breakup to their participation in the class as compared to those in the control group. The tentative findings are an important preliminary step in assessing the benefits of relationship education in reducing the risk of psychological aggression among college students.

A Study on the Relationship between Teacher Self Efficacy and Burnout

Science.gov (United States)

Savas, Ahmet Cezmi; Bozgeyik, Yunus; Eser, Ismail

2014-01-01

The major purpose of the study was to examine the relationship between teacher self efficacy and burnout. In order to collect the related data, "Maslach Burnout Inventory" and "Teacher Sense of Efficacy Scale" were used. The sample of the study consisted of 163 randomly chosen teachers who worked in various primary and…

Parenting self-efficacy moderates linkage between partner relationship dissatisfaction and avoidant infant-mother attachment: A Dutch study

NARCIS (Netherlands)

Casse, J.; Oosterman, M.; Schuengel, C.

2016-01-01

The early infant-mother attachment relationship is part of a network of close relationships in which the relationship between parents is especially relevant. Evidence for linkages between maternal satisfaction with the partner relationship and infant-mother attachment is equivocal. The current study

Potential Reciprocal Relationship between Motivation and Achievement: A Longitudinal Study

Science.gov (United States)

Liu, Yuan; Hou, Shumeng

2018-01-01

Among the non-cognitive factors that influence academic achievement, intrinsic motivation has been found to be a potential reciprocal factor. The present study aims to determine the causal relationship between other types of motivation and academic achievement. For this purpose, a large-scale data survey, the National Education Longitudinal Study…

A study on the relationship between organizational structure and organizational agility: A case study of insurance firm

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Javad Sadeghi

2012-09-01

Full Text Available The primary aim of this survey is to study the relationship between organizational structure and organizational agility in an insurance company in Iran. The statistical population includes 300 employees and managers of the proposed insurance company across in Tehran province, Iran and a sample of 73 people are selected, randomly for the survey. Questionnaire is used as a major tool of data collection. Validity of the questionnaire is confirmed through content validity by professors and experts. Reliability of the questionnaire was calculated using Cronbach alpha. SPSS software is used for data analysis. Research findings illustrate there is a significant relationship between organizational agility and two dimensions of organizational structure, i.e. formalization and centralization. No significant relationship was observed between complexity and organizational agility.

The relationship between leadership and organizational culture: a study carried out in an HEI

OpenAIRE

Andressa Gonçalves; Nicole Pasini Trevisol; Mauricio Capobianco Lopes; Joseane da Silva Soethe

2015-01-01

This research aimed to identify leadership styles and the type of organizational culture present in the institution of higher education studied, as well as the relationship between these two artefacts in the educational context studied. To this end, theoretical frameworks were sought as the concept of organizational culture, transformational and transactional leadership and also the relationship between culture and leadership. Data were collected through a “in situ” questionnaire ...

Learning About Love: A Meta-Analytic Study of Individually-Oriented Relationship Education Programs for Adolescents and Emerging Adults.

Science.gov (United States)

Simpson, David M; Leonhardt, Nathan D; Hawkins, Alan J

2018-03-01

Despite recent policy initiatives and substantial federal funding of individually oriented relationship education programs for youth, there have been no meta-analytic reviews of this growing field. This meta-analytic study draws on 17 control-group studies and 13 one-group/pre-post studies to evaluate the effectiveness of relationship education programs on adolescents' and emerging adults' relationship knowledge, attitudes, and skills. Overall, control-group studies produced a medium effect (d = .36); one-group/pre-post studies also produced a medium effect (d = .47). However, the lack of studies with long-term follow-ups of relationship behaviors in the young adult years is a serious weakness in the field, limiting what we can say about the value of these programs for helping youth achieve their aspirations for healthy romantic relationships and stable marriages.

Influence of social relationship domains and their combinations on incident dementia: a prospective cohort study.

Science.gov (United States)

Saito, Tami; Murata, Chiyoe; Saito, Masashige; Takeda, Tokunori; Kondo, Katsunori

2018-01-01

Social relationships consist of mutually related but distinct dimensions. It remains unclear how these domains independently contribute to incident dementia. This large-scale, prospective cohort study examines associations between the social relationship domains as well as their combinations and incident dementia among community-dwelling older adults. We analysed data from 13 984 community-dwelling adults aged 65+ without long-term care needs living in Aichi prefecture in Japan. Incident dementia was assessed based on the Long-term Care Insurance records, followed for 3436 days from the baseline survey conducted in 2003. Three social relationships domains (social support, social networks and social activities) were further divided into a total of eight subdomains. A social relationship diversity score was calculated using the social relationship domains which were significantly related to incident dementia. A Cox proportional hazards model showed that being married, exchanging support with family members, having contact with friends, participating in community groups and engaging in paid work were related to a lower likelihood of developing incident dementia, controlling for covariates and other social relationship domains. The diversity scores, ranging from 0 to 5, were linearly associated with incident dementia (psocial relationship subdomains which were negatively related to incident dementia, suggesting that dementia may potentially be prevented by enhancing these social relationships. Future studies should examine independent pathways between each social relationship domain and incident dementia. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

The Effect of Relationship Marketing towards Customers' Loyalty Mediated by Relationship Quality (Case Study in Priority Bank in Niaga

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Endang Ruswanti

2016-10-01

Full Text Available A large number of banks let people be more free in choosing the best bank for their needs. People can freely switch from one bank to another which makes the loyalty level of bank customers decrease, even though the efforts and cost spent for maintaining the customers is cheaper than the efforts and cost spent on getting new customers. Relationship is one of the answers to the problem, relationship marketing is a marketing principle which emphasizes and takes effort in maintaining good long term relationship with customers. This research aims to, analyze the influence competence, communication, and conflict handling towards relationship quality, mediated by relationship quality, and towards customer loyalty. The research was conducted by collecting quantitative data through questionnaires distributed to 130 respondents. The objects of this research were the priority customers at Niaga Bank, and it used purposive sampling technique. This research conducted by using Structural Equation Model method. The result of this research showed that, (1 relationship marketing which consists of competence component, communication, and conflict handling have significant influence and positively towards relationship quality, partially and simultaneously, (2 relationship marketing have significant influence and positively towards customer loyalty which is mediated by relationship quality, and (3 relationship quality have significant influence and positively towards customer loyalty.

Benchmarking Supplier Development: An Empirical Case Study of Validating a Framework to Improve Buyer-Supplier Relationship

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Shahzad Khuram

2016-03-01

Full Text Available In today’s dynamic business environment, firms are required to utilize efficiently and effectively all the useful resources to gain competitive advantage. Supplier development has evolved as an important strategic instrument to improve buyer supplier relationships. For that reason, this study focuses on providing the strategic significance of supplier development approaches to improve business relationships. By using qualitative research method, an integrated framework of supplier development and buyer-supplier relationship development has been tested and validated in a Finnish case company to provide empirical evidence. It particularly investigates how supplier development approaches can develop buyer-supplier relationships. The study present a set of propositions that identify significant supplier development approaches critical for the development of buyer-supplier relationships and develop a theoretical framework that specifies how these different supplier development approaches support in order to strengthen the relationships. The results are produced from an in-depth case study by implementing the proposed research framework. The findings reveal that supplier development strategies i.e., supplier incentives and direct involvements strongly effect in developing buyer-supplier relationships. Further research may focus on considering in-depth investigation of trust and communication factors along with propositions developed in the study to find out general applicability in dynamic business environment. Proposed integrated framework along with propositions is a unique combination of useful solutions for tactical and strategic management’s decision making and also valid for academic researchers to develop supplier development theories.

An exploratory study of close supplier-manufacturer relationships

OpenAIRE

Goffin, Keith; Lemke, Fred; Szwejczewski, Marek

2006-01-01

Close relationships with selected suppliers can enable manufacturers to reduce costs, improve quality and enhance new product development. Although the advantages of close co-operation are widely acknowledged in the literature, the specific attributes of such relationships are not well understood. To address this gap, 39 managers responsible for purchasing were interviewed using a technique from psychology, which is particularly effective at uncovering the characteristics of...

Providing supportive care to cancer patients: a study on inter-organizational relationships

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Kevin Brazil

2008-02-01

Full Text Available Background: Supportive cancer care (SCC has historically been provided by organizations that work independently and possess limited inter-organizational coordination. Despite the recognition that SCC services must be better coordinated, little research has been done to examine inter-organizational relationships that would enable this goal. Objective: The purpose of this study was to describe relationships among programs that support those affected by cancer. Through this description the study objective was to identify the optimal approach to coordinating SCC in the community. Methods: Senior administrators in programs that provided care to persons and their families living with or affected by cancer participated in a personal interview. Setting: South-central Ontario, Canada. Study population: administrators from 43 (97% eligible programs consented to participate in the study. Results: Network analysis revealed a diffuse system where centralization was greater in operational than administrative activities. A greater number of provider cliques were present at the operational level than the administrative level. Respondents identified several priorities to improve the coordination of cancer care in the community including: improving standards of care; establishing a regional coordinating body; increasing resources; and improving communication between programs. Conclusion: Our results point to the importance of developing a better understanding on the types of relationships that exist among service programs if effective integrated models of care are to be developed.

Can you tell that I'm in a relationship? Attachment and relationship visibility on Facebook.

Science.gov (United States)

Emery, Lydia F; Muise, Amy; Dix, Emily L; Le, Benjamin

2014-11-01

People often attempt to shape others' perceptions of them, but the role of romantic relationships in this process is unknown. The present set of studies investigates relationship visibility, the centrality of relationships in the self-images that people convey to others. We propose that attachment underlies relationship visibility and test this hypothesis across three studies in the context of Facebook. Avoidant individuals showed low desire for relationship visibility, whereas anxious individuals reported high desired visibility (Studies 1 and 2); however, similar motives drove both groups' actual relationship visibility (Study 1). Moreover, both avoidant individuals and their partners were less likely to make their relationships visible (Studies 1 and 3). On a daily basis, when people felt more insecure about their partner's feelings, they tended to make their relationships visible (Study 3). These studies highlight the role of relationships in how people portray themselves to others. © 2014 by the Society for Personality and Social Psychology, Inc.

Characteristics of successful and failed mentoring relationships: a qualitative study across two academic health centers.

Science.gov (United States)

Straus, Sharon E; Johnson, Mallory O; Marquez, Christine; Feldman, Mitchell D

2013-01-01

To explore the mentor-mentee relationship with a focus on determining the characteristics of effective mentors and mentees and understanding the factors influencing successful and failed mentoring relationships. The authors completed a qualitative study through the Departments of Medicine at the University of Toronto Faculty of Medicine and the University of California, San Francisco, School of Medicine between March 2010 and January 2011. They conducted individual, semistructured interviews with faculty members from different career streams and ranks and analyzed transcripts of the interviews, drawing on grounded theory. The authors completed interviews with 54 faculty members and identified a number of themes, including the characteristics of effective mentors and mentees, actions of effective mentors, characteristics of successful and failed mentoring relationships, and tactics for successful mentoring relationships. Successful mentoring relationships were characterized by reciprocity, mutual respect, clear expectations, personal connection, and shared values. Failed mentoring relationships were characterized by poor communication, lack of commitment, personality differences, perceived (or real) competition, conflicts of interest, and the mentor's lack of experience. Successful mentorship is vital to career success and satisfaction for both mentors and mentees. Yet challenges continue to inhibit faculty members from receiving effective mentorship. Given the importance of mentorship on faculty members' careers, future studies must address the association between a failed mentoring relationship and a faculty member's career success, how to assess different approaches to mediating failed mentoring relationships, and how to evaluate strategies for effective mentorship throughout a faculty member's career.

A Study on the Relationship between Human Resource Management Practices and Organizational Performance

OpenAIRE

Özden AKIN; Hayat Ebru ERDOST ÇOLAK

2012-01-01

The main goal of this study is to investigate the relationship between organizational performance variables and Human Resource Management practices. Workforce planning, training and development, performance appraisal, rewarding, firm-employee relationship, and internal communication are used as human resource management practices. Employee turnover rate, employee productivity, and sales are used as organizational performance variables. The results are collected by survey from 108 companies wh...

Natural Mentoring Relationships among Adolescent Mothers: A Study of Resilience

Science.gov (United States)

Hurd, Noelle M.; Zimmerman, Marc A.

2010-01-01

This study focused on natural mentoring relationships between nonparental adults and African American adolescent mothers. Data were collected from 93 adolescent mothers over 5 time points, starting in the adolescent mothers' senior year of high school and ending 5 years after high school. We found that having a natural mentor was related to fewer…

Impact Of The Customer Relationship Management Practices On The Profitability Of Uae Banks. A Comparative Study

OpenAIRE

Agnihotri, Dr Mahesh; Bhavani, Dr.M. Ganga

2015-01-01

Customer Relationship Management (CRM) is a business strategy where by banks builds strong relationships with existing and prospective customers with the goal of increasing organizational profitability. Customer Relationship Management (CRM) Practices provide a competitive edge to any organization including the Banking Sector, this research is an attempt to study the Customer Relationship Management (CRM) Practices in UAE Banks with certain objectives i.e to examine the existing Customer Rela...

Study of relationship between job satisfaction and isolationist (Case study: Road and Urbanization offices of Kurdistan Province

Directory of Open Access Journals (Sweden)

Jamile Ahmadian

2016-10-01

Full Text Available This study examines the relationship between job satisfaction and isolationist behavior in the General Directorate of Roads and Urban's Kurdistan province. The study population included General Directorate of Roads and Urban Development Kurdistan province is limited to the study of the formula for example, Simple random sampling is available to use on the basis of sampling, the number of samples 191 shows. Questionnaires were used to collect data from a questionnaire used in the study were standard. Data with Statistical programs were both descriptive and inferential analysis. The reliability of the questionnaire with Cronbach's alpha coefficient for job satisfaction and isolationist behavior respectively 0.877 and 0.889 was. All assumptions were confirmed at the level of 95% and all relations based on Pearson correlation coefficient test results were confirmed. Based on the findings of job satisfaction Behavior had a significant relationship with isolationist, isolationist behavior to reduce. Finally, this study has provided practical suggestions.

A social work study on relationship between socio-economic factors and mental health

Directory of Open Access Journals (Sweden)

Zeinab Kamrani

2014-07-01

Full Text Available This paper presents a social work study to investigate the effects of employees’ income and age on their mental health. The study has accomplished among a sample of 150 randomly selected employees who worked for Esfahan steel company located in city of Esfahan, Iran. The study uses a standard questionnaire, which is adopted from Goldberg and Williams (2000 [Goldberg, D., & Williams, P. (2000. General health questionnaire (GHQ. Swindon, Wiltshire, UK: NFER Nelson.]. The results of the implementation of ANOVA test have revealed that while there was a significant and positive relationship between employees’ salary and mental health, there was not any meaningful relationship between employees’ age and mental health.

Characteristics of Successful and Failed Mentoring Relationships: A Qualitative Study Across Two Academic Health Centers

Science.gov (United States)

Straus, Sharon E.; Johnson, Mallory O.; Marquez, Christine; Feldman, Mitchell D.

2013-01-01

Purpose To explore the mentor–mentee relationship with a focus on determining the characteristics of effective mentors and mentees and understanding the factors influencing successful and failed mentoring relationships. Method The authors completed a qualitative study through the Departments of Medicine at the University of Toronto Faculty of Medicine and the University of California, San Francisco, School of Medicine between March 2010 and January 2011. They conducted individual, semistructured interviews with faculty members from different career streams and ranks and analyzed transcripts of the interviews, drawing on grounded theory. Results The authors completed interviews with 54 faculty members and identified a number of themes, including the characteristics of effective mentors and mentees, actions of effective mentors, characteristics of successful and failed mentoring relationships, and tactics for successful mentoring relationships. Successful mentoring relationships were characterized by reciprocity, mutual respect, clear expectations, personal connection, and shared values. Failed mentoring relationships were characterized by poor communication, lack of commitment, personality differences, perceived (or real) competition, conflicts of interest, and the mentor’s lack of experience. Conclusions Successful mentorship is vital to career success and satisfaction for both mentors and mentees. Yet challenges continue to inhibit faculty members from receiving effective mentorship. Given the importance of mentorship on faculty members’ careers, future studies must address the association between a failed mentoring relationship and a faculty member’s career success, how to assess different approaches to mediating failed mentoring relationships, and how to evaluate strategies for effective mentorship throughout a faculty member’s career. PMID:23165266

Joys and challenges of relationships in Scotland and New Zealand rural midwifery: A multicentre study.

Science.gov (United States)

Crowther, Susan; Deery, Ruth; Daellenbach, Rea; Davies, Lorna; Gilkison, Andrea; Kensington, Mary; Rankin, Jean

2018-04-21

Globally there are challenges meeting the recruitment and retention needs for rural midwifery. Rural practice is not usually recognised as important and feelings of marginalisation amongst this workforce are apparent. Relationships are interwoven throughout midwifery and are particularly evident in rural settings. However, how these relationships are developed and sustained in rural areas is unclear. To study the significance of relationships in rural midwifery and provide insights to inform midwifery education. Multi-centre study using online surveys and discussion groups across New Zealand and Scotland. Descriptive and template analysis were used to organise, examine and analyse the qualitative data. Rural midwives highlighted how relationships with health organisations, each other and women and their families were both a joy and a challenge. Social capital was a principal theme. Subthemes were (a) working relationships, (b) respectful communication, (c) partnerships, (d) interface tensions, (e) gift of time facilitates relationships. To meet the challenges of rural practice the importance of relationship needs acknowledging. Relationships are created, built and sustained at a distance with others who have little appreciation of the rural context. Social capital for rural midwives is thus characterised by social trust, community solidarity, shared values and working together for mutual benefit. Rural communities generally exhibit high levels of social capital and this is key to sustainable rural midwifery practice. Midwives, educationalists and researchers need to address the skills required for building social capital in rural midwifery practice. These skills are important in midwifery pre- and post-registration curricula. Copyright © 2018 Australian College of Midwives. All rights reserved.

Study of relationship between time overrun and productivity on construction sites

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Ameh, Oko John

2011-12-01

Full Text Available The history of the construction industry worldwide is full of projects that were completed with significant time and cost overruns. In an attempt to reverse this trend, this study aims at establishing the relationship between time overrun and labour productivity on construction sites in Lagos, Nigeria. 43 technical and management staff of some medium and large construction firms based in Lagos, Nigeria were sampled and administered a questionnaire survey. The questionnaire contained 18 causes of project time overrun and 14 causes of low labour productivity which had been identified from the literature reviewed. With these a relationship between project time overrun and low labour productivity was established. Both descriptive and inferential statistics were used in analyzing the data. Results indicate that inadequate funds for the project, inadequate planning before project takeoff, inadequate tools and equipment and delay in delivery of material top the list of major causes of time overrun while the use of wrong construction methods, inadequate construction materials and inaccurate drawing/specification are the key factors causing low labour productivity on construction sites. Significant negative relationship was found between time overrun and labour productivity in construction sites in Nigeria. The study concludes by recommending that early appointment of project managers could ensure proper management of both the human and material resources that could guarantee improved productivity and ultimately save projects from time overrun.

An Investigation of Justice in Supply Chain Trust and Relationship Commitment - An Empirical Study of Pakistan

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Ziaullah Muhammad

2015-03-01

Full Text Available In recent years supply chain integration (SCI has received increasing attention from scholars and practitioners. However, our knowledge of what influences the supply chain integration practice of relationship commitment is still very limited. The objective of this study is to investigate the relationship among supply chain justices (procedural, distributive and interactional, trust and inter-firms relationship commitment in mainland Pakistan. The research variables have considerable importance in the literature of supply chain management (SCM. The conceptual model comprises five hypotheses. Then hypotheses are tested via an empirical study in which data are collected from 170 manufacturers, distributors, suppliers and retailers of main stream spectrum industries in Pakistan. We used exploratory factor analysis (EFA, confirmatory factor analysis (CFA to examine the validity and reliability of the measurement model, and structural equation modeling (SEM to test the hypotheses. The findings delineate that supply chain justices can develop relationship commitment (affective and continuance via establishing trust among supply chain partners. Moreover, this study reveals interesting and useful implications of supply chain justices, trust and relationship commitment for practitioners.

A Study on Sibling Relationships, Life Satisfaction and Loneliness Level of Adolescents

Science.gov (United States)

Soysal, F. Selda Öz

2016-01-01

The purpose of this study was to examine the relation between sibling relationships, life satisfaction, and the loneliness level of adolescents with regard to gender, order of birth, and sibling dyads. The study group consisted of 382 (209 female, 173 male) students in total, who were studying at high schools (regular high school, vocational high…

A study of relationship between emotional intelligence and innovative work behavior of managers

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Mohammad Reza Shojaei

2014-07-01

Full Text Available This paper studies the relationship between emotional intelligence and its components, self-awareness, self-management, social-awareness and relationship-management, with managers’ innovative work behavior. The research statistical population includes 100 managers of private bank branches in the city of Tehran selected with the random sampling method. The research type is descriptive-correlation. The tool for data aggregation is comprised of two questionnaires of emotional intelligence by Bradberry and Greaves (2006 [Bradberry, T., & Greaves, J. (2006. The emotional intelligence quick book: Everything you need to know to put your EQ to work. Simon and Schuster.] and innovative work behavior based on the studies of Janssen (2000 [Janssen, O. (2000. Job demands, perceptions of effort‐reward fairness and innovative work behaviour. Journal of Occupational and organizational psychology, 73(3, 287-302.]. The Pearson correlation coefficient and multiple regression analysis have been used for data analysis. The results indicated that there was a positive and significant relationship between emotional intelligence and its components with innovative work behavior of managers. In addition, regression analysis showed that the self-management variable had the highest effect in estimating the managers’ innovative work behavior followed by relationship-management, self-awareness and social-awareness.

Quantitative Structure-Activity Relationships and Docking Studies of Calcitonin Gene-Related Peptide Antagonists

DEFF Research Database (Denmark)

Jenssen, Håvard; Mehrabian, Mohadeseh; Kyani, Anahita

2012-01-01

Defining the role of calcitonin gene-related peptide in migraine pathogenesis could lead to the application of calcitonin gene-related peptide antagonists as novel migraine therapeutics. In this work, quantitative structure-activity relationship modeling of biological activities of a large range...... of calcitonin gene-related peptide antagonists was performed using a panel of physicochemical descriptors. The computational studies evaluated different variable selection techniques and demonstrated shuffling stepwise multiple linear regression to be superior over genetic algorithm-multiple linear regression....... The linear quantitative structure-activity relationship model revealed better statistical parameters of cross-validation in comparison with the non-linear support vector regression technique. Implementing only five peptide descriptors into this linear quantitative structure-activity relationship model...

Associations between the peer support relationship, service satisfaction and recovery-oriented outcomes: a correlational study.

Science.gov (United States)

Thomas, Elizabeth C; Salzer, Mark S

2017-12-18

The working alliance between non-peer providers and mental health consumers is associated with positive outcomes. It is hypothesized that this factor, in addition to other active support elements, is also positively related to peer support service outcomes. This study evaluates correlates of the peer-to-peer relationship and its unique association with service satisfaction and recovery-oriented outcomes. Participants were 46 adults with serious mental illnesses taking part in a peer-brokered self-directed care intervention. Pearson correlation analyses examined associations among peer relationship factors, services-related variables and recovery-oriented outcomes (i.e. empowerment, recovery and quality of life). Hierarchical multiple regression analyses evaluated associations between relationship factors and outcomes over time, controlling for other possible intervention effects. The peer relationship was not related to number of contacts. There were robust associations between the peer relationship and service satisfaction and some recovery-oriented outcomes at 24-months, but not at 12-months. These associations were not explained by other possible intervention effects. This study contributes to a better understanding of the positive, unique association between the peer-to-peer relationship and outcomes, similar to what is found in non-peer-delivered interventions. Implications for program administrators and policymakers seeking to integrate peer specialists into mental health service systems are discussed.

An empirical study of the relationship between earnings forecasts and risk profile

Directory of Open Access Journals (Sweden)

Malekian Esfandiar

2016-11-01

Full Text Available A new approach to examine the relationship between the excess of forecast based on characteristics toward management forecast and business risk is provided in this research at companies listed on the stock exchange in Tehran.The customary (traditional (approach is based on the regression of management forecast errors of past years. Therefore, the observable and unobservable inputs, such as managements, incentive misalignment, are used to predict management forecast errors. In this study, the future earnings is at first estimated by using characteristics including earnings per share, loss indicator, Neg. accruals per share , Pos. accruals per share ,asset growth , dividend indicator (non-payment of the dividend, Book-to-market value, share price and dividend per share for companies. Based on that, a criterion (CO for estimating the earnings forecast error was developed, which is the alternative forecasted errors. One should notice that, business risk is considered as a measure of company performance. In this study, measures of business risk are volatility of earnings and dividend ratio. Research findings show that, there is a significant relationship between the CO and volatility of earnings, on the contrary there is no significant relationship between this criteria and dividend ratio

Social Relationships and Allostatic Load in the MIDUS Study

Science.gov (United States)

Brooks, Kathryn P.; Gruenwald, Tara; Karlamanga, Arun; Hu, Peifung; Koretz, Brandon; Seeman, Teresa E.

2014-01-01

OBJECTIVE This study examines how the social environment is related to allostatic load (AL), a multi-system index of biological risk. METHODS A national sample of adults (N = 949) aged 34-84 rated their relationships with spouse, family, and friends at two time points 10 years apart. At the second time point, participants completed a biological protocol in which indices of autonomic, hypothalamic-pituitary-adrenal axis, cardiovascular, inflammatory, and metabolic function were obtained and used to create an AL summary score. Generalized estimating equations were used to examine the associations among three aspects of social relationships – social support, social negativity, and frequency of social contact – and AL. RESULTS Higher levels of spouse negativity, family negativity, friend contact, and network level contact were each associated with higher AL, and higher levels of spouse support were associated with lower AL, independent of age, sociodemographic factors, and health covariates. Tests for age interactions suggested that friend support and network support were each associated with higher AL among older adults, but at younger ages there appeared to be no association between friend support and AL and a negative association between network support and AL. For network negativity, there was a marginal interaction such that network negativity was associated with higher AL among younger adults but there was no association among older adults. CONCLUSIONS These findings demonstrate that structural and functional aspects of the social environment are associated with AL, and extend previous work by demonstrating that these associations vary based on the type of relationship assessed and by age. PMID:24447186

Vertical Relationships on the Workplace and their Influence on Employee's Work Motivation: Sociology Case Study

OpenAIRE

Krösslová, Gabriela

2014-01-01

Subject of this bachelor's thesis is "Vertical relationships at the workplace and theirs influence on employee's work motivation". In the theoretical part, I defined key words, such as: Motivation, vertical and horizontal relationships, work sociology etc. I also stated concepts, related to work sociology and motivation. Practical part deals with the qualitative research (case study), which relates to vertical relationships on workplace as one of the key points of work motivation. That resear...

Advances in QSPR/QSTR models of ionic liquids for the design of greener solvents of the future.

Science.gov (United States)

Das, Rudra Narayan; Roy, Kunal

2013-02-01

In order to protect the life of all creatures living in the environment, the toxicity arising from various hazardous chemicals must be controlled. This imposes a serious responsibility on different chemical, pharmaceutical, and other biological industries to produce less harmful chemicals. Among various international initiatives on harmful aspects of chemicals, the 'Green Chemistry' ideology appears to be one of the most highlighted concepts that focus on the use of eco-friendly chemicals. Ionic liquids are a comparatively new addition to the huge garrison of chemical compounds released from the industry. Extensive research on ionic liquids in the past decade has shown them to be highly useful chemicals with a good degree of thermal and chemical stability, appreciable task specificity and minimal environmental release resulting in a notion of 'green chemical'. However, studies have also shown that ionic liquids are not intrinsically non-toxic agents and can pose severe degree of toxicity as well as the risk of bioaccumulation depending upon their structural components. Moreover, ionic liquids possess issues of waste generation during synthesis as well as separation problems. Predictive quantitative structure-activity relationship (QSAR) models constitute a rational opportunity to explore the structural attributes of ionic liquids towards various physicochemical and toxicological endpoints and thereby leading to the design of environmentally more benevolent analogues with higher process selectivity. Such studies on ionic liquids have been less extensive compared to other industrial chemicals. The present review attempts to summarize different QSAR studies performed on these chemicals and also highlights the safety, health and environmental issues along with the application specificity on the dogma of 'green chemistry'.

Preconditions needed for establishing a trusting relationship during health counselling - an interview study.

Science.gov (United States)

Eriksson, Irene; Nilsson, Kerstin

2008-09-01

To examine the preconditions needed by district nurses to build a trusting relationship during health counselling of patients with hypertension. Trust has been found to be an important aspect of the patient-nurse relationship. Little research has focused on how trust is formed in patient-nurse relationships or the conditions the development process requires when working with health counselling; in particular not in relation to hypertension. Qualitative study. Qualitative data were collected through open-ended interviews with all (10) district nurses from three primary health care districts of western Sweden. All interviewees work with the health counselling of patients with hypertension. A latent content analysis was performed with thematic coding of the content of the interviews. The first theme that emerged from the analysis, the nurses' competence, describes the nurses' consciousness of their method of expression, both oral and non-verbal, as well as their pedagogical competence and their ability to be reliable in their profession. The second theme, the patient meeting, describes the continuity in the patient meeting and creating respectful communication. The results show an awareness of preconditions influencing building a trusting relationship. When creating a trusting relationship the communication and pedagogical competences of district nurses have considerable importance. Despite this awareness they state that it is easy to fall into a routinised way of working. The implications of this study might be used as support and guidance for district nurses when developing their competence in health counselling in relations to patients with hypertension. This knowledge is also important when planning for nurse-led clinics for this patient group.

The Viewpoints of Sexually Active Single Women About Premarital Sexual Relationships: A Qualitative Study in the Iranian Context.

Science.gov (United States)

Rahmani, Azam; Merghati-Khoei, Effat; Moghaddam-Banaem, Lida; Hajizadeh, Ebrahim; Montazeri, Ali

2016-03-01

Premarital sexual relationships could harm youth's health in terms of sexually transmitted infections or increased risk of unprotected sexual behaviors. Sexual abstinence has been recommended to prevent young adolescents from adverse outcomes of premarital sexual relationships. The aim of this study was to explore the viewpoints of sexually active single women about premarital sexual relationships in the Iranian context. In this qualitative study, we recruited 41 young women aged 18 to 35 years. Data were collected using focus group discussions and individual interviews. We employed conventional content analysis to analyze the data. Multiple data collection methods, maximum variation sampling, and peer checks were applied to enhance the reliability of the findings. Eight themes emerged from the data analysis: 'acceptance of sexual contact in the context of opposite-sex relationships, 'sexual activity as a guarantee for keeping the boyfriend in the relationship', 'premarital sexual relationship as an undeniable personal right', 'having successful marriage in spite of premarital sexual relationships', 'virginity as an old fashioned phenomenon', 'love as a license for premarital sexual behaviors', 'goal-oriented relationship as a license for premarital sexual behaviors', and 'experiencing premarital sexual relationships in order to gain perfection'. Results of this study could be applied to designing interventions, such as promotion of preventive beliefs or educational programs regarding premarital sexual relationships in conservative societies. These interventions could start within families and continue at schools and universities.

Social relationships and cognitive decline : a systematic review and meta-analysis of longitudinal cohort studies

NARCIS (Netherlands)

Kuiper, Jisca S.; Zuidersma, Marij; Zuidema, Sytse U.; Burgerhof, Johannes G. M.; Stolk, Ronald P.; Oude Voshaar, Richard C.; Smidt, Nynke

Background: Although poor social relationships are assumed to contribute to cognitive decline, meta-analytic approaches have not been applied. Individual study results are mixed and difficult to interpret due to heterogeneity in measures of social relationships. We conducted a systematic review and

Social relationships and cognitive decline: a systematic review and meta-analysis of longitudinal cohort studies

NARCIS (Netherlands)

Kuiper, J.S.; Zuidersma, M.; Zuidema, S.U.; Burgerhof, J.G.; Stolk, R.P.; Oude Voshaar, R.C.; Smidt, N.

2016-01-01

BACKGROUND: Although poor social relationships are assumed to contribute to cognitive decline, meta-analytic approaches have not been applied. Individual study results are mixed and difficult to interpret due to heterogeneity in measures of social relationships. We conducted a systematic review and

Relationship between mechanical sensitivity and postamputation pain: A prospective study

DEFF Research Database (Denmark)

Nikolajsen, Lone; IlKjær, Susanne; Jensen, Troels Staehelin

2000-01-01

of the limb and early (after 1 week) and late (after 6 months) phantom pain. Thirty-five patients scheduled for amputation of the lower limb were examined before, 1 week and 6 months after amputation. On all three examination days pressure-pain thresholds were measured and compared with the simultaneous...... recording of ongoing pain intensity assessed on a visual analogue scale (VAS). There was a weak but significant inverse relationship between preamputation thresholds and early stump and phantom pain. There was no relationship between preamputation thresholds and late stump and phantom pain. One week after...... amputation there was a significant and inverse relationship between mechanical thresholds and phantom pain but no relationship was found after 6 months. The findings suggest that although tenderness of the limb before and after amputation is related to early stump and phantom pain, the relationship is weak...

Resources for work-related well-being: a qualitative study about healthcare employees' experiences of relationships at work.

Science.gov (United States)

Schön Persson, Sophie; Nilsson Lindström, Petra; Pettersson, Pär; Nilsson, Marie; Blomqvist, Kerstin

2018-05-23

The aim of this study was to explore municipal healthcare employees' experiences of relationships with care recipients and colleagues. The specific research questions were when do the relationships enhance well-being, and what prerequisites are needed for such relationships to occur?. Employees in health and social care for older people often depict their work in negative terms, and they often take a high number of sick leaves. Despite the heavy workload, other employees express well-being at work and highlight social relationships as one reason for this. However, a greater understanding of how these relationships can act as resources for workplace well-being is needed. The design of the study was qualitative and exploratory. Qualitative interview studies were conducted with twenty-three healthcare employees in municipal healthcare. Thematic analysis was used to analyse the data. Two themes were identified as resources for promoting relationships between employees and care recipients or colleagues: (i) Being personal - a close interpersonal relationship to a care recipient - and (ii) Colleague belongingness - a sense of togetherness within the working group. Spending quality time together, providing long-term care and providing additional care were antecedents for a close interpersonal relationship with care recipients. Trust, mutual responsibility and cooperation were antecedents for a sense of togetherness within the working group. The findings provide an empirical base to raise awareness of relationships with care recipients and colleagues as health aspects. Relationships among employees in healthcare are vital resources that must be considered to create sustainable workplaces, and consequently improve the quality of care. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Externally predictive single-descriptor based QSPRs for physico-chemical properties of polychlorinated-naphthalenes: Exploring relationships of log S{sub W}, log K{sub OA}, and log K{sub OW} with electron-correlation

Energy Technology Data Exchange (ETDEWEB)

Chayawan; Vikas, E-mail: qlabspu@pu.ac.in

2015-10-15

Highlights: • Aqueous solubility and partition coefficient are modelled using single-parameter. • Electron-correlation observed as a vital predictorof physico-chemical properties. • For octanol-air partition coefficient, energy and polarizability yield best models. • Dipole-moment is found to be worst single-descriptor for the properties analysed. - Abstract: Quantitative structure–property relationships (QSPRs), based only on a single-parameter, are proposed for the prediction of physico-chemical properties, namely, aqueous solubility (log S{sub W}), octanol–water partition coefficient (log K{sub OW}) and octanol–air partition coefficient (log K{sub OA}) of polychloronaphthalenes (PCNs) including all the 75 chloronaphthalene congeners. The QSPR models are developed using molecular descriptors computed through quantum mechanical methods including ab-initio as well as advanced semi-empirical methods. The predictivity of the developed models is tested through state-of-the-art external validation procedures employing an external prediction set of compounds. To analyse the role of instantaneous interactions between electrons (the electron-correlation), the models are also compared with those developed using only the electron-correlation contribution of the quantum chemical descriptor. The electron-correlation contribution towards the chemical hardness and the LUMO energy are observed to be the best predictors for octanol–water partition coefficient, whereas for the octanol–air partition coefficient, the total electronic energy and electron-correlation energy are found to be reliable descriptors, in fact, even better than the polarisability. For aqueous solubility of PCNs, the absolute electronegativity is observed to be the best predictor. This work suggests that the electron-correlation contribution of a quantum-chemical descriptor can be used as a reliable indicator for physico-chemical properties, particularly the partition coefficients.

Relationship stigma and relationship outcomes in interracial and same-sex relationships: Examination of sources and buffers.

Science.gov (United States)

Rosenthal, Lisa; Starks, Tyrel J

2015-12-01

Interracial and same-sex romantic relationships are more common and socially accepted in the United States than ever before; yet, stigmatization of these relationships persists, with consequences for relationship dynamics. We conducted an online survey study with adults living in the United States in interracial and same-sex relationships to examine associations of relationship stigma from family, friends, and public with several relationship outcomes (i.e., investment, satisfaction, intimate partner aggression victimization and perpetration, commitment, intimacy, trust, passion, love, sexual communication, and sexual satisfaction), as well as the potential buffering roles of egalitarianism and dyadic coping. Regression analyses with 480 participants support that above and beyond individually experienced discrimination and other well-known predictors of relationship outcomes, relationship stigma from friends in particular was associated with lower relationship commitment, trust, love, and sexual communication, as well as greater odds of intimate partner aggression victimization. Egalitarianism and dyadic coping moderated some of the associations of relationship stigma from family, friends, and public with relationship outcomes, supporting their potential roles as buffers. These findings suggest many avenues for future research and implications for clinicians working with interracial and same-sex couples, individuals in those couples, and their families. Given increasing prevalence of interracial and same-sex relationships and marriages, more work should continue to explore these couples' experiences and how best to support them. (c) 2015 APA, all rights reserved).

Relationship between indoor radon and lung cancer: a study of feasibility of an epidemiological study. Final report

Energy Technology Data Exchange (ETDEWEB)

Rasmussen, S.; Neuberg, D.; DuMouchel, W.; Kleitman, D.; Chernoff, H.

1981-01-01

This report describes a study to assess the feasibility of an epidemiologic investigation of the relationship between residential radon exposure and lung cancer. Field measurements of residential radon levels in the State of Maine are described. Using these radon measurements and BEIR, 1980 risk assessments, it is estimated that at most 10% of lung cancers in Maine can be considered attributable to residential radon exposure. Calculations are made of sample sizes necessary for a case-control study of radon and lung cancer, for several levels of radon and smoking health effects. The effects of misclassification of exposure variables on the probability of detecting a radon health effect are discussed. A comparison is made of three different mathematical models which could be used for sample size estimation. Dollar cost estimates are given for conducting an epidemiologic case-control study of the relationship between residential radon exposure and lung cancer.

Relationship between indoor radon and lung cancer: a study of feasibility of an epidemiological study. Final report

International Nuclear Information System (INIS)

Rasmussen, S.; Neuberg, D.; DuMouchel, W.; Kleitman, D.; Chernoff, H.

1981-01-01

This report describes a study to assess the feasibility of an epidemiologic investigation of the relationship between residential radon exposure and lung cancer. Field measurements of residential radon levels in the State of Maine are described. Using these radon measurements and BEIR, 1980 risk assessments, it is estimated that at most 10% of lung cancers in Maine can be considered attributable to residential radon exposure. Calculations are made of sample sizes necessary for a case-control study of radon and lung cancer, for several levels of radon and smoking health effects. The effects of misclassification of exposure variables on the probability of detecting a radon health effect are discussed. A comparison is made of three different mathematical models which could be used for sample size estimation. Dollar cost estimates are given for conducting an epidemiologic case-control study of the relationship between residential radon exposure and lung cancer

What is the relationship between diversity and performance? A study about the relationship between the proportion of people with disabilities in the productivity of Brazilian firms

NARCIS (Netherlands)

Ferreira, L.C.M. (Luciana Carvalho de Mesquita); Rais, L.A. (Luciano Aversani)

2016-01-01

textabstractPurpose – This study aims to analyze the relationship between greater participation of people with disabilities in Brazilian firms and productivity as a performance indicator. Design/methodology/approach – To test the relationship between the proportion of PwD and the productivity of

The Association of Externalizing Behavior and Parent-Child Relationships: An Intergenerational Study

Science.gov (United States)

Brook, Judith S.; Lee, Jung Yeon; Finch, Stephen J.; Brown, Elaine N.

2012-01-01

We investigated the influence of the child's behavior on the quality of the mutual parent-child attachment relationships across three generations. We did so using a prospective longitudinal study which spanned 20 years from adolescence through adulthood. Study participants completed in-class questionnaires as students in the East Harlem area of…

The Protective Effects of Adaptability, Study Skills, and Social Skills on Externalizing Student-Teacher Relationships

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Fisher, Sycarah D.; Reynolds, Jennifer L.; Sheehan, Chelsea E.

2016-01-01

Although students with externalizing behaviors inherently exhibit behaviors that contribute to poor teacher relationships, little research has examined the positive characteristics these students may possess that serve to facilitate positive teacher relationships. This study explores the moderating effects of adaptability, social skills, and study…

Chemically Aware Model Builder (camb): an R package for property and bioactivity modelling of small molecules.

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Murrell, Daniel S; Cortes-Ciriano, Isidro; van Westen, Gerard J P; Stott, Ian P; Bender, Andreas; Malliavin, Thérèse E; Glen, Robert C

2015-01-01

In silico predictive models have proved to be valuable for the optimisation of compound potency, selectivity and safety profiles in the drug discovery process. camb is an R package that provides an environment for the rapid generation of quantitative Structure-Property and Structure-Activity models for small molecules (including QSAR, QSPR, QSAM, PCM) and is aimed at both advanced and beginner R users. camb's capabilities include the standardisation of chemical structure representation, computation of 905 one-dimensional and 14 fingerprint type descriptors for small molecules, 8 types of amino acid descriptors, 13 whole protein sequence descriptors, filtering methods for feature selection, generation of predictive models (using an interface to the R package caret), as well as techniques to create model ensembles using techniques from the R package caretEnsemble). Results can be visualised through high-quality, customisable plots (R package ggplot2). Overall, camb constitutes an open-source framework to perform the following steps: (1) compound standardisation, (2) molecular and protein descriptor calculation, (3) descriptor pre-processing and model training, visualisation and validation, and (4) bioactivity/property prediction for new molecules. camb aims to speed model generation, in order to provide reproducibility and tests of robustness. QSPR and proteochemometric case studies are included which demonstrate camb's application.Graphical abstractFrom compounds and data to models: a complete model building workflow in one package.

A social work study on relationship between transactional and laissez-fair leadership style and personality traits: A case study of educational system

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Hajar Jannesari

2013-03-01

Full Text Available Leadership style plays an essential role on personality trait in educational systems. In this paper, we present a study among 180 school principals in city of Khomeinishahr, located in province of Esfahan, Iran. The study selects a sample of 123 principals and examines ten hypotheses including the effects of personality trait neuroticism, extroversion, resilience, participative, conscientiousness on leadership style. The study examined the effects of two groups of leadership, namely transactional leadership and Laissez-fair leadership styles on five personality traits. The results have shown that there were some meaningful relationship between transactional leadership and personality trait extraversion, resilience, participative and consciousness but there was not meaningful relationship between transactional leadership and personality trait neuroticism. In addition, while there were meaningful and positive relationship between Laissez-fair leadership style and personality trait extraversion as well as being resilience, our survey did not find any meaningful relationship between Laissez-fair leadership style and personality trait neuroticism, extraversion and being consciousness.

Studies on Morphological and Phylogenetic Relationship of Salak Pondoh Varieties (Salacca zalacca (Gaert. Voss. at Sleman Highlands

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NUR HIDAYAH

2000-07-01

Full Text Available The objectives of the study were to know the morphological variation of salak-plants (Salacca zalacca (Gaert. Voss. and their relationship. The study was conducted in May to April 2000, at Turi and Pakem of Sleman district, Yogyakarta. Samples were randomly taken, 5 plants of each variety were studied their morphological characters such as stem, leaf, flower and fruit. The data collected were then analyzed descriptive comparatively and their relationships were then determined. The result of the study indicate that there were at least 8 varieties of salak at Sleman district, green-, black-, yellow-, manggala-, red-yellow-, golden-, red-, and red-black pondoh. Morphological differences among varieties were markedly different. The closest relationship was found between variety of red-black- and black pondoh, while the farthest relationship among the varieties was manggala pondoh.

To Study the Relationship between Creativity & Personality among High School Students

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Perveen, Shaheen; Ramzan, Shaikh Imran

2013-01-01

The central dimension of human personality is extroversion and introversion, the present study is therefore focussed on the relationship between creativity and extraversion and introversion personality traits. A teacher can identify extrovertism and introvertism among the students easily on the basis of their behaviour and habits. Teacher can also…

Trust in the context of management relationships: an empirical study.

OpenAIRE

Atkinson, Sally; Butcher, David

2003-01-01

This paper responds to calls for exploration of the dynamics of trust in the embedded context of interpersonal managerial relationships. Building on theoretical distinctions between different types of interpersonal relationships established in social psychology, the paper proposes a generic typology of interpersonal managerial relationships, along with associated hypotheses and implications for trust. The later part of the paper then reports the results from an initial explorat...

A European study of E-business maturity and ICT-benefits: is there a conditional relationship?

NARCIS (Netherlands)

Batenburg, R.; Constantiou, I.

2009-01-01

The present study explores the relationship between the e-business maturity and the perceived benefits from (Information and Communication Technologies) ICT at the firm level. We aim to debunk this relationship in terms of its strength and stability, and to explore the conditions which may influence

Study on functional relationships between ergonomics indexes of manual performance

Science.gov (United States)

Hu, Hui-Min; Ding, Li; Chen, Shou-Ping; Yang, Chun-Xin; Yuan, Xiu-Gan

This paper investigates functional relationships between some of the key ergonomics indexes in manual performance, and attempts to condense the ergonomics appraisal indexes system and thus evaluate hand performance wearing EVA (extravehicular activity) glove, design and improve EVA glove's performance. Four types of ergonomics indexes were studied, i.e., dexterity, tactile sensibility (TS), strength and fatigue. Two test items of insert sticks into a holes-board (ISIHB) and nuts-bolts assembly task (NBAT) were used to measure dexterity, while shape discrimination (SD) was employed for TS, and grip force (GF) for strength and fatigue. The variables measured in this investigation included accomplishing time (AT) of ISIHB and NBAT, correct rate (CR) of SD, maximal grip force (MGF), instant grip force (IGF) and endurance time of grip force (ETGF). Experiments were conducted on 31 undergraduates (eight female and 23 male) with two experiment conditions of bare-hand group and gloved hand group. Results demonstrated that dexterity and TS performance of gloved hand group declined significantly compared with those of bare-hand group (pfatigue between two conditions (p>0.05). Four effective functional relationships were developed between four pairs of ergonomics indexes in bare-hand group. In gloved hand group, in addition to above-mentioned four pairs of relationships, another formula was found, which was y^=0.02061+0.01233x ( p<0.01, dexterity and TS).

Relationship between Organizational Communication Satisfaction and Organizational Justice: An Empirical Study

OpenAIRE

Gök, Sibel; Karatuna, Işıl; Özkılıçcı, Gökçe

2013-01-01

This study aimed to investigate the relationship between organizational communication satisfaction and organizational justice and to explore the impact of communication satisfaction on perceived justice in a group of university employees. Data were obtained through questionnaires among 481 academics working in public and private universities in Turkey. The research measures used in this study were the Communication Satisfaction Questionnaire of Downs and Hazen and the Organizational Justice S...

A study on relationship between knowledge management and organizational change in learning organizations: A case study of cable industry

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Mohammad Emami

2013-10-01

Full Text Available This paper presents an empirical investigation to study the relationship between knowledge management and organizational change in one of Iranian producers of wire and cable. The proposed study of this paper designs a questionnaire consists of 23 questions in Likert scale and distributes it among 76 randomly people who work for this organization. The results of Spearman correlation coefficients show that harvest index, refining, organizing, disseminating and applying knowledge have positive and meaningful relationship with organizational change. Managers need to develop organizational change to integrate the wealth of knowledge in various sectors and having knowledge of internal and external forces.

Fundamental studies, reference values and relationship to menstrual cycle on Prolactin RIA BEAD II

International Nuclear Information System (INIS)

Kobayashi, Midori; Sakai, Rinko; Satoh, Shigekiyo; Maruyama, Kiyoji; Kanai, Masamitsu

1989-01-01

We have tried fundamental studies, reference values and relationship to menstrual cycle on Prolactin RIA BEAD II kit which has a method of IRMA using monocronal antibody. On clinical studies, we investigated change of serum prolactin level during the menstrual cycle and relationship to other hormones (LH, FSH, estradiol, progesterone). It was the result that prolactin level of follicular phase was lower than that of preavulatory phase and luteal phase. We conclude that change of prolactin level during the menstrual cycle is related with change of estradiol level. (author)

Fundamental studies, reference values and relationship to menstrual cycle on Prolactin RIA BEAD II

Energy Technology Data Exchange (ETDEWEB)

Kobayashi, Midori; Sakai, Rinko; Satoh, Shigekiyo; Maruyama, Kiyoji; Kanai, Masamitsu (Shinshu Univ., Matsumoto, Nagano (Japan). Faculty of Medicine)

1989-06-01

We have tried fundamental studies, reference values and relationship to menstrual cycle on Prolactin RIA BEAD II kit which has a method of IRMA using monocronal antibody. On clinical studies, we investigated change of serum prolactin level during the menstrual cycle and relationship to other hormones (LH, FSH, estradiol, progesterone). It was the result that prolactin level of follicular phase was lower than that of preavulatory phase and luteal phase. We conclude that change of prolactin level during the menstrual cycle is related with change of estradiol level. (author).

The caregiving relationship and quality of life among partners of stroke survivors: A cross-sectional study

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Wilson Keith G

2011-05-01

Full Text Available Abstract Background Since the majority of stroke survivors return home following their stroke, families play a pivotal role in their care. Few studies have addressed both positive and negative aspects of this role or the broader construct of health-related quality of life (HRQL. Furthermore, little consideration has been given to the context of care in terms of relationship quality, and reciprocity. The present study examined the relationships between caregiver quality of life (HRQL, caregiver role, relationship satisfaction, balance and reciprocity in caregivers of partners who had experienced a stroke. Specific hypotheses were made based on equity theory in social relations. Methods Fifty-six partner caregivers completed a postal survey that included measures of HRQL (SF-36, caregiver role (negative and positive aspects, relationship satisfaction, reciprocity and balance. Data were also collected on the care recipients' quality of life (Stroke Specific Quality of Life scale. Results Compared to a normative sample, caregivers' HRQL was lower for all SF-36 domains. Care recipient and caregiver age, care recipient quality of life and caregiver role (negative significantly predicted physical component summary scores on the SF-36, while care recipient quality of life and caregiver role (negative significantly correlated with mental component summary scores. Relationship satisfaction and intrinsic rewards of caregiving were found to be important predictors of positive aspects of the caregiver role. Caregivers who viewed their relationship as less balanced in terms of give and take had significantly greater caregiver burden than those who viewed their relationship as more equitable. Conclusions The study highlights the importance of taking a broader approach to examining partner caregiving in the context of stroke, in terms of the caregiving relationship and their influence on the health and well-being of caregivers.

Sexual Behavior and Nonsexual Deviance: A Sibling Study of Their Relationship.

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Rowe, David C.; And Others

1989-01-01

Two studies, one involving college students and the other high school students, found a strong relationship between relatively early sexual intimacy and nonsexual forms of deviance. Siblings were more alike than chance in deviance and in physical sexual behavior. Additionally, an association was found between one sibling's sexual intimacy with a…

Mining for elastic constants of intermetallics from the charge density landscape

Energy Technology Data Exchange (ETDEWEB)

Kong, Chang Sun; Broderick, Scott R. [Department of Materials Science and Engineering, Iowa State University, Ames, IA 50011 (United States); Jones, Travis E. [Molecular Theory Group, Colorado School of Mines, Golden, CO 80401 (United States); Loyola, Claudia [Department of Materials Science and Engineering, Iowa State University, Ames, IA 50011 (United States); Eberhart, Mark E. [Molecular Theory Group, Colorado School of Mines, Golden, CO 80401 (United States); Rajan, Krishna, E-mail: krajan@iastate.edu [Department of Materials Science and Engineering, Iowa State University, Ames, IA 50011 (United States)

2015-02-01

There is a significant challenge in designing new materials for targeted properties based on their electronic structure. While in principle this goal can be met using knowledge of the electron charge density, the relationships between the density and properties are largely unknown. To help overcome this problem we develop a quantitative structure–property relationship (QSPR) between the charge density and the elastic constants for B2 intermetallics. Using a combination of informatics techniques for screening all the potentially relevant charge density descriptors, we find that C{sub 11} and C{sub 44} are determined solely from the magnitude of the charge density at its critical points, while C{sub 12} is determined by the shape of the charge density at its critical points. From this reduced charge density selection space, we develop models for predicting the elastic constants of an expanded number of intermetallic systems, which we then use to predict the mechanical stability of new systems. Having reduced the descriptors necessary for modeling elastic constants, statistical learning approaches may then be used to predict the reduced knowledge-based required as a function of the constituent characteristics.

Detection of patient psychological distress and longitudinal patient-doctor relationships: a cross-sectional study.

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Ridd, Matthew; Lewis, Glyn; Peters, Tim J; Salisbury, Chris

2012-03-01

Psychological distress in patients who attend their GP is thought to be under-recognised. However, it is likely that both disclosure and detection are influenced by how well the patient and doctor know each another. To examine whether patient-doctor depth of relationship is associated with identification of psychological distress. Cross-sectional study in general practices in and around Bristol, England. Patients (aged ≥16 years) were asked to complete a questionnaire and consent to their electronic medical records being reviewed. Study GPs independently assessed patient psychological distress. Multivariable logistic regression was used to look for associations between patient-doctor depth of relationship and GP detection of patient psychological distress (defined according to the 12-item General Health Questionnaire, GHQ-12). There were 643 eligible appointments with 31 GPs. In total, 541 (84.1%) patients returned questionnaires and 490 (76.2%) consented to their records being reviewed. Patient-doctor depth of relationship was not associated with GP detection of mild to severe patient psychological distress (adjusted odds ratio [OR] 0.94, 95% CI = 0.87 to 1.02) but, in secondary analyses, it was associated with the identification of moderate to severe distress (adjusted OR 1.13, 95% CI = 1.02 to 1.26). GPs reported more patient psychological distress in patients who reported a greater depth of relationship but this did not relate to patients' GHQ-12 scores. Evidence to support an association between patient-doctor depth of relationship and improved GP detection of patients with psychological distress was weak, except in those patients who GPs thought were more distressed. GPs may overestimate emotional distress in patients who report deeper patient-doctor relationships.

A social work study on relationship between leadership style and organization change: A case study of Semnan high schools' teachers

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Mohammad Reza Iravani

2012-10-01

Full Text Available The primary objective of this survey is to study the relationship between leadership style among teachers who work in high schools and their orientation on organizational change. The study is performed among students who attended guided schools in province of Semnan, Iran. There are five hypotheses associated with the proposed study of this paper including managers' attitudes on change based on demographic characteristics, the relationship between leadership style and organizational change, the effects of different leadership styles and the organizational change orientation in terms of demographical characteristics. Statistical population includes all teachers who for high schools in city of Semnan, Iran and the study used a sample of 373 people who were randomly selected from three regions of the city. The proposed study used standard leadership questionnaire based on initiating structure and consideration originally developed at Ohio university in two dimensions with 30 questions. The questionnaire also used another type questionnaire consists of 32 questions with three dimensions of structure, technology and employee. The results indicate that there is no meaningful relationship between leadership style and gender, leadership style and job experience, organizational change and gender, management change and gender.

Gender, Emotion Work, and Relationship Quality: A Daily Diary Study

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Curran, Melissa A.; McDaniel, Brandon T.; Pollitt, Amanda M.; Totenhagen, Casey J.

2015-01-01

We use the gender relations perspective from feminist theorizing to investigate how gender and daily emotion work predict daily relationship quality in 74 couples (148 individuals in dating, cohabiting, or married relationships) primarily from the southwest U.S. Emotion work is characterized by activities that enhance others’ emotional well-being. We examined emotion work two ways: trait (individuals’ average levels) and state (individuals’ daily fluctuations). We examined actor and partner effects of emotion work and tested for gender differences. As outcome variables, we included six types of daily relationship quality: love, commitment, satisfaction, closeness, ambivalence, and conflict. This approach allowed us to predict three aspects of relationship quality: average levels, daily fluctuations, and volatility (overall daily variability across a week). Three patterns emerged. First, emotion work predicted relationship quality in this diverse set of couples. Second, gender differences were minimal for fixed effects: Trait and state emotion work predicted higher average scores on, and positive daily increases in, individuals’ own positive relationship quality and lower average ambivalence. Third, gender differences were more robust for volatility: For partner effects, having a partner who reported higher average emotion work predicted lower volatility in love, satisfaction, and closeness for women versus greater volatility in love and commitment for men. Neither gender nor emotion work predicted average levels, daily fluctuations, or volatility in conflict. We discuss implications and future directions pertaining to the unique role of gender in understanding the associations between daily emotion work and volatility in daily relationship quality for relational partners. PMID:26508808

Interpersonal relationship and lay third parties' side-taking preference : A cross-cultural study among Chinese and Dutch

NARCIS (Netherlands)

Yang, Huadong; van de Vliert, Evert; Shi, Kan

In two comparative studies, both conducted in China and in the Netherlands, we investigated the effect of an asymmetric relationship on lay third parties' side-taking preference in an interpersonal dispute. The first study shows that a perceived close relationship with one of the disputants

Interpersonal relationship and lay third parties; side taking preference: A cross-cultural study among Chinese and Dutch

NARCIS (Netherlands)

Yang, H.; van de Vliert, Evert; Shi, Kan

2007-01-01

In two comparative studies, both conducted in China and in the Netherlands, we investigated the effect of an asymmetric relationship on lay third parties' side-taking preference in an interpersonal dispute. The first study shows that a perceived close relationship with one of the disputants

Personality and Sibling Relationships.

Science.gov (United States)

Furman, Wyndol; Lanthier, Richard P.

1996-01-01

This study examined the role personality variables play in sibling relationships. It proposed that the characteristics of sibling relationships are influenced by: family constellation variables such as birth order, gender, and age spacing; parent-child relationships including quality of relationship and parent management of siblings; and the…

Dimensions of quality perceived in B2B relationships: a case study in the public sector

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Gabriel Lara Rodrigues

2015-12-01

Full Text Available The increasing production horizontalization expanded the discussion on quality beyond the border of the organization. Furthermore, the links between buyers and suppliers have now a greater focus, beyond the strictly transactional view of production or service to encompass more dynamic prospects such as relationships and networks. In this context, in the light of the dimensions of Relationship Quality between Companies proposed by Holmlund (1997, the present research aims to identify the specificities which characterize the relationship quality of a public agency and its private suppliers, more specifically in reprography and printing service contracts. The study found that the Quality of Relationship between companies involves different people and functions with different needs and importance. It has been found that the idea of reciprocal, long-term and mutually beneficial relationships, with shared information and resource transfer standards, is discouraged by many legal regulations that limit the government’s relationship with its service providers, especially regarding length of relationship, cost and flexibility.

Sexual relationships among men who have sex with men in Hanoi, Vietnam: a qualitative interview study.

Science.gov (United States)

Bengtsson, Linus; Thorson, Anna; Thanh, Vu Pham Nguyen; Allebeck, Peter; Popenoe, Rebecca

2013-02-05

The prevalence of HIV among men who have sex with men (MSM) in Vietnam's two largest cities, Hanoi and Ho Chi Minh City, may be above 10%. The aim of this study was to explore sexual relationship patterns and experiences among MSM in Hanoi, to inform HIV preventive efforts. Using purposive sampling we recruited 17 MSM in Hanoi, Vietnam, for in-depth interviews. Participants were aged between 19 and 48 years and came from diverse socio-economic backgrounds. Interviews were tape-recorded, transcribed verbatim, and translated into English. Content analysis was used. Almost all men in the study saw their same-sex attraction as part of their "nature". Many informants had secret but rich social lives within the MSM social circles in Hanoi. However, poor men had difficulties connecting to these networks. Lifetime sexual partner numbers ranged from one to 200. Seven participants had at some point in their lives been in relationships lasting from one to four years. For several men, relationships were not primarily centered on romantic feelings but instead intimately connected to economic and practical dependence. Sexual relationships varied greatly in terms of emotional attachment, commitment, trust, relationship ideals, sexual satisfaction and exchange of money or gifts. Faithfulness was highly valued but largely seen as unobtainable. Several informants felt strong family pressure to marry a woman and have children. This study contextualizes sexual relationships among MSM in Hanoi and highlights the extent to which HIV prevention activities need to not only consider HIV prevention in the context of casual sexual encounters but also how to adequately target preventive efforts that can reach MSM in relationships.

The relationship between elderly suicide rates and different components of education: a cross-national study

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Ajit Shah

2012-07-01

Full Text Available BACKGROUND: Two recent studies reported a curvilinear (U-shaped between elderly suicide rates and educational attainment measured by the United Nation’s Education Index. A study examining the curvilinear (U-shaped relationship between elderly suicide rates and the individual components of the Education Index (adult literacy rate, percentage of children of relevant age group enrolled in primary schools and percentage of children of relevant age group enrolled for secondary schools and one other measure of educational attainment (youth literacy rate was undertaken to partial out the effects of the individual components of Education Index on elderly suicides. METHODS: A cross-national study examining the relationship between elderly suicide rates (Y-axis and different measures of educational attainment (X-axis was undertaken using data from the World Health Organization and the United Nations data banks using Curve estimation regression models. RESULTS: The relationship between elderly suicide rates with the adult literacy rate, the percentage of children of relevant age group enrolled for secondary schools and the youth literacy rate was curvilinear (U-shaped curve. This relationship was absent with the percentage of children of relevant age group enrolled in primary schools. CONCLUSIONS: Given the cross-sectional study design, a causal relationship between elderly suicide rates and measures of educational attainment, including the adult literacy rate, the percentage of children of relevant age group enrolled for secondary schools and the youth literacy rate, cannot be assumed. However, the findings suggest that future studies of elderly suicide rates and educational attainment should focus on the adult literacy rate, the percentage of children of relevant age group enrolled for secondary schools and the youth literacy rate as measures of educational attainment.

A longitudinal study on the maternal–fetal relationship and postnatal maternal sensitivity

NARCIS (Netherlands)

Maas, A.J.B.M.; de Cock, E.S.A.; Vreeswijk, C.M.J.M.; Vingerhoets, A.J.J.M.; van Bakel, H.J.A.

2016-01-01

Objective: The present study examined whether early signs of maternal sensitivity can be detected during pregnancy by focusing on the maternal–fetal relationship and postnatal maternal sensitivity. Background: Earlier research has identified maternal sensitive behaviour as an important factor for

The Therapeutic Relationship and Cognitive Behavioural Therapy: A Case Study of an Adolescent Girl With Depression

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Cheryl Joy Easterbrook

2017-02-01

Full Text Available The therapeutic relationship in Cognitive Behavioural Therapy (CBT has been argued to play an essential role in positive outcomes in therapy. However, it is described as necessary and yet, secondary to technique, often receiving little attention in the training of CBT therapists. This case study explores a trainee psychologist’s experience of finding difficulty in feeling authentic and the application of CBT techniques with her client. This difficulty informed the research question; what is the value of the therapeutic relationship in CBT? A hermeneutic approach with a strong emphasis on phenomenology, is used to explore the therapeutic process and the therapeutic relationship that developed between therapist and client. Qualitative descriptions of 11 sessions are divided into themes, these are discussed in relation to what happened in therapy, and are then discussed further regarding discovery and process into the therapeutic relationship. Conclusions from this case study could possibly reveal the value of the therapeutic relationship when working from a CBT approach, and how it seemed to enable the client to achieve her goal in therapy.

A panel study on the relationship between corruption and government size

OpenAIRE

Go, Kotera; Okada, Keisuke; Samreth, Sovannroeun

2010-01-01

Using panel data from 1996 to 2005, this paper shows that the effect of government size on corruption is positive at a low level of democracy, but it is negative at a high level. This finding could fill the gaps in previous studies whose findings on the relationship between corruption and government size are controversial.

Chronic Arsenic Toxicity: Statistical Study of the Relationships Between Urinary Arsenic, Selenium and Antimony

OpenAIRE

Analía Boemo, BS; Irene María Lomniczi, PhD; Elsa Mónica Farfán Torres, PhD

2012-01-01

Background. The groundwater of Argentina’s Chaco plain presents arsenic levels above those suitable for human consumption. Studies suggest skin disorders among local populations caused by arsenic intake. The relationship between urinary arsenic and arsenic in drinking water is well known, but urinary arsenic alone is not enough for risk assessment due to modulating factors such as the intake of selenium and antimony. Objectives. Determining the relationship between urinary arsenic, seleniu...

Relationship satisfaction in lesbian and heterosexual couples before and after assisted reproduction: a longitudinal follow-up study.

Science.gov (United States)

Borneskog, Catrin; Lampic, Claudia; Sydsjö, Gunilla; Bladh, Marie; Svanberg, Agneta Skoog

2014-12-12

More and more lesbian couples are planning parenthood through donor insemination and IVF and the number of planned lesbian families is growing in Sweden and other western countries. Research has shown that lesbian couples report as much overall satisfaction in their relationships as do heterosexual couples. However, although parenthood is highly desired, many parents are unaware of the demands of parenthood and the strain on their relationship that the arrival of the baby might bring. The aim of this study was to compare lesbian and heterosexual couples' perceptions of relationship satisfaction at a three-year follow up after assisted reproduction. The present study is a part of the Swedish study on gamete donation, a prospective longitudinal cohort study. The present study constitutes a three-year follow up assessment of lesbian and heterosexual couples after assisted reproduction. Participants requesting assisted reproduction at all fertility clinics performing gamete donation in Sweden, were recruited consecutively during 2005-2008. A total of 114 lesbian women (57 treated women and 57 partners) and 126 heterosexual women and men (63 women and 63 men) participated. Participants responded to the ENRICH inventory at two time points during 2005-2011; at the commencement of treatment (time point 1) and about three years after treatment termination (time point 3). To evaluate the bivariate relationships between the groups (heterosexual and lesbian) and socio-demographic factors Pearson's Chi- square test was used. Kolmogorov-Smirnov test was used for testing of normality, Mann-Whitney U- test to examine differences in ENRICH between the groups and paired samples t-test to examine scores over time. Lesbian couples reported higher relationship satisfaction than heterosexual couples, however the heterosexual couples satisfaction with relationship quality was not low. Both lesbian and heterosexual couples would be classified accordingly to ENRICH-typology as vitalized or

A study on relationship between audit quality and earnings management in Iranian banking industry

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Mohammad Masihi

2013-12-01

Full Text Available This paper presents an empirical investigation to study the relationship between audit quality and earnings management in Iranian banking industry. The proposed study gathers the necessary information from 18 different Iranian banks over the period 2005-2012. The study considers the effects of three independent variables including type of auditing, tenure of auditing and size of bank on earning managements. The result of our survey has indicated that there was a meaningful and reverse relationship between type of accounting and earnings management. In addition, the longer an auditing firm perform auditing program, the better the firm reports earnings management. Finally, as the size of firm increases, there is a better earnings management.

Development of Adolescent Relationships

OpenAIRE

de Goede, I.H.A.

2009-01-01

This dissertation on “Development of Adolescent Relationships” addresses relationships with parents, friends, and romantic partners in adolescence from a developmental perspective. By studying both parent-adolescent relationships and peer relationships at the same time, as well as interrelations between these types of relationships, this dissertation provides more information on the processes taking place in relationships during adolescence. Findings indicate that parent-adolescent relationsh...

Pengaruh Customer Relationship Marketing Dan Nilai Nasabah Terhadap Loyalitas Nasabah (Studi Kasus: Pada PT Bank Muamalat Cabang Jambi) the Effect of Customer Relationship Marketing and Customer Value to Customer Loyalty (Case Study: Muamalat Bank Ja

OpenAIRE

Harun, Harniza

2011-01-01

This study analyzes of the effect of customer relationship marketing  and customer value to customer loyalty. The object of this study is the Jambi branch of Bank Muamalat Indonesia. Research problem refers to the phenomenon of the business to the criticism and suggestions received from the ministry of consumer behavior refers to rumsan problem How to Influence Customer relationship marketing on customer loyalty. The research objective was formulated to seek answers to the flow that affect cu...

Social relationships and risk of dementia : a systematic review and meta-analysis of longitudinal cohort studies

NARCIS (Netherlands)

Kuiper, J.S.; Zuidersma, M.; Oude Voshaar, R.C.; Zuidema, S.U.; Heuvel, van den E.R.; Stolk, R.P.; Smidt, N.

2015-01-01

It is unclear to what extent poor social relationships are related to the development of dementia. A comprehensive systematic literature search identified 19 longitudinal cohort studies investigating the association between various social relationship factors and incident dementia in the general

Social relationships and risk of dementia : A systematic review and meta-analysis of longitudinal cohort studies

NARCIS (Netherlands)

Kuiper, Jisca S.; Zuidersma, Marij; Oude Voshaar, Richard; Zuidema, Sytse; van den Heuvel, Edwin R.; Stolk, Ronald P.; Smidt, Nynke

It is unclear to what extent poor social relationships are related to the development of dementia. A comprehensive systematic literature search identified 19 longitudinal cohort studies investigating the association between various social relationship factors and incident dementia in the general

Exploring the interpersonal relationships in street-based male sex work: results from an Australian qualitative study.

Science.gov (United States)

Leary, David; Minichiello, Victor

2007-01-01

While the literature on male sex work has increased significantly over the past decade, few studies examine the influence of relational dynamics in the lives of those engaged in male sex work. This qualitative study, conducted with a sample of male street sex workers in Sydney, Australia, explores how relationships color their involvement with sex work. The findings reveal the complexity of their relationships and how their interactions with others shape their engagement in sex work. The data also offer insight into how exit pathways are influenced by money and relationships that occur within this particular male sex work setting. Implications for health policy and intervention are considered.

Detection of patient psychological distress and longitudinal patient–doctor relationships: a cross-sectional study

Science.gov (United States)

Ridd, Matthew; Lewis, Glyn; Peters, Tim J; Salisbury, Chris

2012-01-01

Background Psychological distress in patients who attend their GP is thought to be under-recognised. However, it is likely that both disclosure and detection are influenced by how well the patient and doctor know each another. Aim To examine whether patient–doctor depth of relationship is associated with identification of psychological distress. Design and setting Cross-sectional study in general practices in and around Bristol, England. Method Patients (aged ≥16 years) were asked to complete a questionnaire and consent to their electronic medical records being reviewed. Study GPs independently assessed patient psychological distress. Multivariable logistic regression was used to look for associations between patient–doctor depth of relationship and GP detection of patient psychological distress (defined according to the 12-item General Health Questionnaire, GHQ-12). Results There were 643 eligible appointments with 31 GPs. In total, 541 (84.1%) patients returned questionnaires and 490 (76.2%) consented to their records being reviewed. Patient–doctor depth of relationship was not associated with GP detection of mild to severe patient psychological distress (adjusted odds ratio [OR] 0.94, 95% CI = 0.87 to 1.02) but, in secondary analyses, it was associated with the identification of moderate to severe distress (adjusted OR 1.13, 95% CI = 1.02 to 1.26). GPs reported more patient psychological distress in patients who reported a greater depth of relationship but this did not relate to patients' GHQ-12 scores. Conclusion Evidence to support an association between patient–doctor depth of relationship and improved GP detection of patients with psychological distress was weak, except in those patients who GPs thought were more distressed. GPs may overestimate emotional distress in patients who report deeper patient–doctor relationships. PMID:22429433

A study on relationship between female employees’ organizational citizenship behavior and job satisfaction within organization

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Majid Iranshahi

2013-09-01

Full Text Available This paper presents an investigation to assess the relationship between female employees’ organizational citizenship behavior and job satisfaction within organization. A questionnaire is designed and distributed among employees who work in city of Qom, Iran and after analyzing the responses by SPSS software program, the relationships between variables are assessed by Pearson test after confirming the normality of the data using Kolmogrov-Smirnov test. The results of the studies reflect a strong relationship between citizen-organization behavior of female employees and job satisfaction. In addition, the survey examines six sub-hypotheses and confirms that there are positive and meaningful relationships between female employees’ custom, altruism, work consciousness, mutual coordination, fairness and courtesy on one side and job satisfaction on the other side.

How to estimate exposure when studying the temperature-mortality relationship? A case study of the Paris area.

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Schaeffer, Laura; de Crouy-Chanel, Perrine; Wagner, Vérène; Desplat, Julien; Pascal, Mathilde

2016-01-01

Time series studies assessing the effect of temperature on mortality generally use temperatures measured by a single weather station. In the Paris region, there is a substantial measurement network, and a variety of exposure indicators created from multiple stations can be tested. The aim of this study is to test the influence of exposure indicators on the temperature-mortality relationship in the Paris region. The relationship between temperature and non-accidental mortality was assessed based on a time series analysis using Poisson regression and a generalised additive model. Twenty-five stations in Paris and its three neighbouring departments were used to create four exposure indicators. These indicators were (1) the temperature recorded by one reference station, (2) a simple average of the temperatures of all stations, (3) an average weighted on the departmental population and (4) a classification of the stations based on land use and an average weighted on the population in each class. The relative risks and the Akaike criteria were similar for all the exposure indicators. The estimated temperature-mortality relationship therefore did not appear to be significantly affected by the indicator used, regardless of study zone (departments or region) or age group. The increase in temperatures from the 90(th) to the 99(th) percentile of the temperature distribution led to a significant increase in mortality over 75 years (RR = 1.10 [95% CI, 1.07; 1.14]). Conversely, the decrease in temperature between the 10(th) and 1(st) percentile had a significant effect on the mortality under 75 years (RR = 1.04 [95% CI, 1.01; 1.06]). In the Paris area, there is no added value in taking multiple climatic stations into account when estimating exposure in time series studies. Methods to better represent the subtle temperature variations in densely populated areas in epidemiological studies are needed.

Progress in customer relationship management adoption: a cross-sector study

OpenAIRE

Meadows, Maureen; Dibb, Sally

2012-01-01

Although customer relationship management (CRM) is widely used by organizations to capture and manage customer data, the process of implementation can be problematic. This article takes a multi-sector view of CRM implementation in three areas of the UK services sector: banking and finance; professional services; and the government/public sector. The study captures variations in CRM practice and implementation across these sectors, applying an existing framework of CRM implementation to tease ...

The relationship between socio-economic inequality and criminal victimisation: a prospective study

NARCIS (Netherlands)

Wohlfarth, T.; Winkel, F. W.; Ybema, J. F.; van den Brink, W.

2001-01-01

This study investigates the relationship of socio-economic inequality (SEI) with criminal victimisation. It is hypothesised that disadvantage in terms of SEI is associated with increased risk of being victimised and with increased distress following victimisation. Two concepts of SEI are applied:

The relationship between socio-economic inequality and criminal victimization: a prospective study.

NARCIS (Netherlands)

Wohlfarth, T.D.; Winkel, F.W.

2001-01-01

Background: This study investigates the relationship of socio-economic inequality (SEI) with criminal victimisation. It is hypothesised that disadvantage in terms of SEI is associated with increased risk of being victimised and with increased distress following victimisation. Two concepts of SEI are

Development of Self-Esteem and Relationship Satisfaction in Couples: Two Longitudinal Studies

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Erol, Ruth Yasemin; Orth, Ulrich

2014-01-01

We examined the effects of self-esteem development on the development of relationship satisfaction in 2 samples of couples. Study 1 used data from both partners of 885 couples assessed 5 times over 12 years, and Study 2 used data from both partners of 6,116 couples assessed 3 times over 15 years. The pattern of results was similar across the 2…

Relationship between mental health and spiritual wellbeing among hemodialysis patients: a correlation study.

Science.gov (United States)

Martínez, Beatriz Bertolaccini; Custódio, Rodrigo Pereira

2014-01-01

The stress of living with a terminal disease has a negative impact on the mental health of hemodialysis (HD) patients. Spirituality is a potential coping mechanism for stressful experiences. Studies on the relationship between spirituality and mental health among HD patients are scarce. The purpose of this study was to evaluate the relationship between mental health and spiritual well-being among HD patients. Cross-sectional observational study on hemodialysis patients at a single center in Brazil, between January and December 2011. Mental health was assessed using the General Health Questionnaire and spiritual wellbeing was assessed using the Spiritual Wellbeing Scale; 150 HD patients participated in the study. A significant correlation was found between mental health and spiritual wellbeing (P = 0.001). Spiritual wellbeing was the strongest predictor of mental health, psychological distress, sleep disturbance and psychosomatic complaints. Poor mental health was associated with lower spiritual wellbeing. This has important implications for delivery of palliative care to HD patients.

The Relationship between Food Intake and Bladder Cancer: A Case Control Study

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2015-01-01

Full Text Available Background & aim: Bladder cancer is the second most common cancer of the urinary tract worldwide and the third most common cancer among Iranian males. Despite the relative high incidence of bladder cancer in Iran, no study has examined the relationship between dietary factors and bladder cancer. The aim of the present study was to investigate this relationship. Methods: The present case-control study was carried out on fifty-five patients with bladder cancer and including 110 cancer-free patients as controls. Dietary intake was evaluated using a food frequency questionnaire. To investigate the relationship between food items and bladder cancer, the subjects were classified according to the tertile of food items. The odds ratio was calculated for each tertile and the first tertile was considered as the reference group. Results: Our findings revealed that among food groups, animal fat (OR=19.76, fat (OR=12.92, junk foods (OR=8.1, organ meat (OR=5.47, processed meat (OR=5.34 and sweets (OR=3.62 were involved in the development of bladder cancer. In bladder carcinogenesis, an inverse association was recorded between consumption of low fat dairy products (OR=0.31, yoghurt (OR =0.14, fish (OR = 0.13, specific fruits (OR=0.13 and the development of bladder cancer. Conclusion: Animal products and sources of saturated fat are associated with an increased in risk of bladder cancer. The protective effect of olive oil, specific fruits, vegetables, low-fat dairy fermented was observed to reduce the risk of bladder cancer.

Relationships between moment magnitude and fault parameters: theoretical and semi-empirical relationships

Science.gov (United States)

Wang, Haiyun; Tao, Xiaxin

2003-12-01

Fault parameters are important in earthquake hazard analysis. In this paper, theoretical relationships between moment magnitude and fault parameters including subsurface rupture length, downdip rupture width, rupture area, and average slip over the fault surface are deduced based on seismological theory. These theoretical relationships are further simplified by applying similarity conditions and an unique form is established. Then, combining the simplified theoretical relationships between moment magnitude and fault parameters with seismic source data selected in this study, a practical semi-empirical relationship is established. The seismic source data selected is also to used to derive empirical relationships between moment magnitude and fault parameters by the ordinary least square regression method. Comparisons between semi-empirical relationships and empirical relationships show that the former depict distribution trends of data better than the latter. It is also observed that downdip rupture widths of strike slip faults are saturated when moment magnitude is more than 7.0, but downdip rupture widths of dip slip faults are not saturated in the moment magnitude ranges of this study.

Structures and Relationships between the Business Executive and Information Technology Executive at the University: A Mixed Methods Study

Science.gov (United States)

Hollman, Angela K.

2014-01-01

This study uses an explanatory mixed methods methodology to attempt to determine the reporting relationships between business and IT executives within the university. The study also explores IT and business executives thoughts on these relationships. Supporting research from organizational studies and business-IT alignment is combined in order to…

Empirical Study on the Relationships of Internet Banking Quality, Customer Value, and Customer Satisfaction

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Umbas KRISNANTO

2017-06-01

Full Text Available The purpose of this conducted study was to test the direct and indirect effects of internet banking quality and customer value to customer satisfaction. This study uses descriptive analysis and multiple regression analysis to examine these relationships. The study is based on a survey conducted with respondents who use internet banking in their day-to-day activities, and all questionnaire items are deemed valid and reliable. For data analysis, the descriptive analysis for the indicators, dimensions, and variables proved to be in a good category. Research findings and implications of the regression analysis show that internet banking quality and customer value had a greater direct impact on customer satisfaction, rather the partial relationships of these variables to satisfaction. In the partial relationships, customer value has a higher influence on customer satisfaction, than internet banking quality. As a research recommendation, banks should provide a more humanistic internet banking service for better consumer satisfaction. A major research limitation of the study is that it does not measure service quality of internet banking, and only focuses on customers of internet banking use of one single bank. The originality of this research relies on the insights of internet banking quality leading to customer satisfaction and increasing the value of a bank to its main target markets.

Computational study of the structure-free radical scavenging relationship of procyanidins.

Science.gov (United States)

Mendoza-Wilson, Ana María; Castro-Arredondo, Sergio Ivan; Balandrán-Quintana, René Renato

2014-10-15

Procyanidins (PCs) are effective free radical scavengers, however, their antioxidant ability is variable because they have different degrees of polymerisation, are composed by distinct types of subunits and are very susceptible to changes in conformation. In this work the structure-free radical scavenging relationship of monomers, dimers and trimers of PCs was studied through the hydrogen atom transfer (HAT), sequential proton-loss electron-transfer (SPLET) and single electron transfer followed by proton transfer (SET-PT) mechanisms in aqueous phase, employing the Density Functional Theory (DFT) computational method. The structure-free radical scavenging relationship of PCs showed a very similar behaviour in HAT and SET-PT mechanisms, but very different in the SPLET mechanism. The structural factor that showed more effects on the ability of PCs to scavenge free radicals in aqueous phase was the conformation. Copyright © 2014 Elsevier Ltd. All rights reserved.

The Relationship Between the Customer Relationship Management and Patients' Loyalty to Hospitals.

Science.gov (United States)

Hajikhani, Shadi; Tabibi, Seyed Jamaledin; Riahi, Leila

2015-06-25

Customer Relationship Management (CRM) with its various components has been considered as a tool causing customers' loyalty. The present study aims to investigate the relationship between the various components of customer relationship management and patients' loyalty to the place of their treatment. This cross sectional and descriptive-analytical study was conducted among nurses and hospitalized patients in inpatient wards in selected hospitals in 2014. Using the stratified random sampling method, 224 valid and reliable researcher-drafted questionnaires were completed for CRM by nurses and 359 questionnaires were completed by patients for patients' loyalty in the studied wards. Data were analyzed using the SPSS(20) software. There was no statistically significant relationship between the level of patients' loyalty and organizational indicators, information technology and knowledge management (P Value>0.05). However, there was a statistically significant relationship between loyalty and the dimensions of the service process (P Value=0.04), human resources (P Value=0.002) and CRM (P Value=0.038). The strength of these relationships were 34, 40 and 36 percent, respectively all of which were positive. Customer Relationship Management is a tool for improving influencing factors on patients' satisfaction and loyalty. Therefore, attempts to implement customer relationship management as a process for improving hospitals performance and improving communication between service providers in hospitals and customers leading to enhance patients' loyalty should be taken into account by managers and policy makers in the health sectors.

The Relationship Between the Customer Relationship Management and Patients’ Loyalty to Hospitals

Science.gov (United States)

Hajikhani, Shadi; Tabibi, Seyed Jamaledin; Riahi, Leila

2016-01-01

Background and Aim: Customer Relationship Management (CRM) with its various components has been considered as a tool causing customers’ loyalty. The present study aims to investigate the relationship between the various components of customer relationship management and patients’ loyalty to the place of their treatment. Methods: This cross sectional and descriptive-analytical study was conducted among nurses and hospitalized patients in inpatient wards in selected hospitals in 2014. Using the stratified random sampling method, 224 valid and reliable researcher-drafted questionnaires were completed for CRM by nurses and 359 questionnaires were completed by patients for patients’ loyalty in the studied wards. Data were analyzed using the SPSS20 software. Results: There was no statistically significant relationship between the level of patients’ loyalty and organizational indicators, information technology and knowledge management (P Value>0.05). However, there was a statistically significant relationship between loyalty and the dimensions of the service process (P Value=0.04), human resources (P Value=0.002) and CRM (P Value=0.038). The strength of these relationships were 34, 40 and 36 percent, respectively all of which were positive. Conclusion: Customer Relationship Management is a tool for improving influencing factors on patients’ satisfaction and loyalty. Therefore, attempts to implement customer relationship management as a process for improving hospitals performance and improving communication between service providers in hospitals and customers leading to enhance patients’ loyalty should be taken into account by managers and policy makers in the health sectors. PMID:26493416

The necessary conditions of engagement for the therapeutic relationship in physiotherapy: an interpretive description study.

Science.gov (United States)

Miciak, Maxi; Mayan, Maria; Brown, Cary; Joyce, Anthony S; Gross, Douglas P

2018-01-01

The therapeutic relationship between patient and physiotherapist is a central component of patient-centred care and has been positively associated with better physiotherapy clinical outcomes. Despite its influence, we do not know what conditions enable a physiotherapist and patient to establish and maintain a therapeutic relationship. This knowledge has implications for how clinicians approach their interactions with patients and for the development of an assessment tool that accurately reflects the nature of the therapeutic relationship. Therefore, this study's aim was to identify and provide in-depth descriptions of the necessary conditions of engagement of the therapeutic relationship between physiotherapists and patients. Interpretive description was the qualitative methodological orientation used to identify and describe the conditions that reflect and are practically relevant to clinical practice. Eleven physiotherapists with a minimum 5 years of clinical experience and seven adult patients with musculoskeletal disorders were purposively sampled from private practice clinics in Edmonton, Canada. The in-person, semi-structured interviews were completed in a location of the participant's choice and were audio recorded and transcribed. Qualitative content analysis was used to analyze the textual data and constant comparison techniques were integrated to refine the categories and sub-categories. Rigour strategies used throughout the study were peer debrief, interview notes, reflexive journaling, memoing, member reflections, audit trail, and external audit. Four conditions were identified as necessary for establishing a therapeutic relationship: present , receptive , genuine , and committed . These conditions represent the intentions and attitudes of physiotherapists and patients engaging in the clinical interaction. Although distinct, the conditions appear related as being present and receptive create a foundation for being genuine and committed. These

Study on conversion relationships of compressive strength indexes for recycled lightweight aggregate concrete

Science.gov (United States)

Zhang, Xiang-gang; Yang, Jian-hui; Kuang, Xiao-mei

2017-01-01

In order to study cube compressive strength and axial compressive strength of recycled lightweight aggregate concrete(RLAC), and conversion relationship between the two, with the replacement rate of recycled lightweight coarse aggregate as change parameters, 15 standard cube test specimens and 15 standard prism test specimens were produced to carry out the test. Then compressive strength of test specimens were measured, and the law of different replacement rate of recycled lightweight coarse aggregate influencing compressive strength of RLAC was analyzed, as the method of statistical regression adopted, the conversion relationships between of cube compressive strength and axial compressive strength of RLAC was obtained. It is shown that compressive strength of RLAC are lower than compressive strength of ordinary concrete; and that compressive strength of RLAC gradually decreases as replacement rate of recycled lightweight coarse aggregate increases; as well as, the conversion relationship between axial compressive strength and cube compressive strength of RLAC is different from ordinary concrete; based on the experimental data, conversion relationship formula between compressive strength indexes of RLAC was established. It is suggested that the replacement rate of recycled lightweight aggregate should be controlled within 25%.

A study on relationship between working capital and profitability

Directory of Open Access Journals (Sweden)

Hassan Ghodrati

2014-08-01

Full Text Available This paper studies the relationship between working capital management and profitability of accepted corporations in Tehran Stock Exchange over the period 2008-2012. The study selected 66 firms as a statistical sample based on Cochran formula and simple random selection. In this study, variables including the average period of collecting accordance, periods of circulation of inventories, the average period of debt payment, and cycle of cash conversion on the factories operating profits are studied. The research method is applied and collection of data is solidarity, the Pierson and Regression solidarity are used. Results show that variables of capital investment management and profitability were in opposite direction. If the period of collecting accordance, period of debt payment, period of circulation of inventories and the cycle of cash conversion increase, it decreases the period profitability and the manager can decrease the period of debt payment, period of cash conversion to the least amount of positive value for affiliate.

Relationship between Marketing Strategies and Governance Mechanisms: A Study in Exploration Chain Beef Cattle

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Filipe Quevedo-Silva

2015-09-01

Full Text Available The relationship between actors has been unspoilt by marketing through the bias of Transaction Costs Economics. Some authors suggest that a marketing strategy can directly impact the transactional characteristics and hence the governance mechanisms chosen to coordinate transactions. Studies suggest that future work in the field of marketing include, among other factors, aspects related to the relationship between the actors. In this context, this article aims to analyze how marketing strategies can affect the choice of governance mechanisms. The study object is the chain of beef, view their representation to the national economy. To this end, we conducted a qualitative study using semi-structured interviews with various actors in the chain. It was possible to verify the existence of the relationship between marketing strategy and governance structure. In one of the cases, product differentiation, translated into more specific assets, led the producer to perform a relational contract with the fridge and to distribute your product, make an integration with retailers, through the opening of a boutique of meat. Factor that was not observed in transactions involving producers on products without distinction, for which the transactions via spot market are prevalent.  

Relationships between gastric slow wave frequency, velocity, and extracellular amplitude studied by a joint experimental-theoretical approach.

Science.gov (United States)

Wang, T H-H; Du, P; Angeli, T R; Paskaranandavadivel, N; Erickson, J C; Abell, T L; Cheng, L K; O'Grady, G

2018-01-01

Gastric slow wave dysrhythmias are accompanied by deviations in frequency, velocity, and extracellular amplitude, but the inherent association between these parameters in normal activity still requires clarification. This study quantified these associations using a joint experimental-theoretical approach. Gastric pacing was conducted in pigs with simultaneous high-resolution slow wave mapping (32-256 electrodes; 4-7.6 mm spacing). Relationships between period, velocity, and amplitude were quantified and correlated for each wavefront. Human data from two existing mapping control cohorts were analyzed to extract and correlate these same parameters. A validated biophysically based ICC model was also applied in silico to quantify velocity-period relationships during entrainment simulations and velocity-amplitude relationships from membrane potential equations. Porcine pacing studies identified positive correlations for velocity-period (0.13 mm s -1 per 1 s, r 2 =.63, Prelationships and demonstrated dependence on the slow wave recovery phase. Simulated membrane potential relationships were close to these experimental results (100 μV per 1 mm s -1 ). These data quantify the relationships between slow wave frequency, velocity, and extracellular amplitude. The results from both human and porcine studies were in keeping with biophysical models, demonstrating concordance with ICC biophysics. These relationships are important in the regulation of gastric motility and will help to guide interpretations of dysrhythmias. © 2017 John Wiley & Sons Ltd.

Relationship-contingent self-esteem and the ups and downs of romantic relationships.

Science.gov (United States)

Knee, C Raymond; Canevello, Amy; Bush, Amber L; Cook, Astrid

2008-09-01

Relationship-contingent self-esteem (RCSE) emerges from perspectives on authenticity, need fulfillment, and relationship functioning and is an unhealthy form of self-esteem that depends on one's relationship. Four studies provided evidence of convergent, discriminant, incremental, and predictive validity for RCSE. Study 1 tested associations between RCSE and several conceptually related and unrelated constructs in multiple samples. In Study 2, the authors employed an event-contingent diary procedure to examine reports of self-esteem as a function of everyday relationship events. The association between event valence and changes in self-esteem became stronger with RCSE, and this interaction remained controlling for several parallel interactions by other constructs. Study 3 employed an interval-contingent diary procedure and found support for a mediation model in which the moderating role of RCSE largely occurred through momentary emotions, which in turn predicted momentary self-esteem. Study 4 sampled couples and found that partners who were both higher in RCSE felt more committed but not more satisfied or close.

Relationship satisfaction reduces the risk of maternal infectious diseases in pregnancy: the Norwegian Mother and Child Cohort Study.

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Roger Ekeberg Henriksen

Full Text Available The aims of this study were to explore the degree to which relationship satisfaction predicts the risk of infectious diseases during pregnancy and to examine whether relationship satisfaction moderates the association between stressful life events and the risk of infections.This was a prospective study based on data from the Norwegian Mother and Child Cohort Study (MoBa conducted by the Norwegian Institute of Public Health. Pregnant women (n = 67,244 completed questionnaires concerning relationship satisfaction and nine different categories of infectious diseases as well as socioeconomic characteristics and stressful life events. Associations between the predictor variables and the infectious diseases were assessed by logistic regression analyses. A multiple regression analysis was performed to assess a possible interaction of relationship satisfaction with stressful life events on the risk for infectious diseases.After controlling for marital status, age, education, income, and stressful life events, high levels of relationship satisfaction at week 15 of gestation were found to predict a significantly lower risk for eight categories of infectious diseases at gestational weeks 17-30. No significant interaction effect was found between relationship satisfaction and stressful life events on the risk for infections.

Relationship satisfaction reduces the risk of maternal infectious diseases in pregnancy: the Norwegian Mother and Child Cohort Study.

Science.gov (United States)

Henriksen, Roger Ekeberg; Torsheim, Torbjørn; Thuen, Frode

2015-01-01

The aims of this study were to explore the degree to which relationship satisfaction predicts the risk of infectious diseases during pregnancy and to examine whether relationship satisfaction moderates the association between stressful life events and the risk of infections. This was a prospective study based on data from the Norwegian Mother and Child Cohort Study (MoBa) conducted by the Norwegian Institute of Public Health. Pregnant women (n = 67,244) completed questionnaires concerning relationship satisfaction and nine different categories of infectious diseases as well as socioeconomic characteristics and stressful life events. Associations between the predictor variables and the infectious diseases were assessed by logistic regression analyses. A multiple regression analysis was performed to assess a possible interaction of relationship satisfaction with stressful life events on the risk for infectious diseases. After controlling for marital status, age, education, income, and stressful life events, high levels of relationship satisfaction at week 15 of gestation were found to predict a significantly lower risk for eight categories of infectious diseases at gestational weeks 17-30. No significant interaction effect was found between relationship satisfaction and stressful life events on the risk for infections.

Development of Adolescent Relationships

NARCIS (Netherlands)

de Goede, I.H.A.

2009-01-01

This dissertation on “Development of Adolescent Relationships” addresses relationships with parents, friends, and romantic partners in adolescence from a developmental perspective. By studying both parent-adolescent relationships and peer relationships at the same time, as well as interrelations

Preadolescents' Relationships with Pet Dogs: Relationship Continuity and Associations with Adjustment.

Science.gov (United States)

Kerns, Kathryn A; Koehn, Amanda J; van Dulmen, Manfred H M; Stuart-Parrigon, Kaela L; Coifman, Karin G

2017-01-01

Research on human-animal interaction in children has been studied in isolation rather than integrated with core theories of children's relationships. This study is one of the first to examine how children's relationships with pet dogs are related to their human relationships (parent-child attachments, friendships) and to child adjustment, and to include observational assessment of children's interactions with their pet dog. Children (9 to 11 years old, n = 99) completed questionnaires regarding relationships with pet dogs, parents, and friends. Half the children were observed interacting with their pet dog. Children and teachers reported children's adjustment. Children who felt closer to their dogs were more securely attached to mothers and fathers, and reported more positive qualities and less conflict with friends. Children with more secure attachments to mothers, and greater companionship with dogs, interacted more with their dogs. Parental attachment and friendship quality, but not the pet dog relationship, were related to child adjustment.

Personality Effects on Romantic Relationship Quality through Friendship Quality: A Ten-Year Longitudinal Study in Youths

Science.gov (United States)

Yu, Rongqin; Branje, Susan; Keijsers, Loes; Meeus, Wim H. J.

2014-01-01

This study examined whether individuals with different personality types (i.e., overcontrollers, undercontrollers, resilients) had different friendship quality development throughout adolescence. It also investigated whether personality types were indirectly related to romantic relationship quality in young adulthood, via friendship quality development in adolescence. The study employed six waves of longitudinal questionnaire data from Dutch youths who had a romantic relationship when they were young adults. Two age cohorts were followed, from 12 to 21 years and from 16 to 25 years, respectively. Findings showed that resilients reported higher mean levels of friendship quality during adolescence (i.e., more support from, less negative interaction with and less dominance from their best friend) than both overcontrollers and undercontrollers. Through the mean levels of friendship quality throughout adolescence, resilients indirectly experienced higher romantic relationship quality during young adulthood than both overcontrollers and undercontrollers. Thus, results provide support for a developmental model in which adolescent friendship quality is a mechanism linking personality types with young adulthood romantic relationship quality. PMID:25232964

Gene, Brain, and Behavior Relationships in Fragile X Syndrome: Evidence from Neuroimaging Studies

Science.gov (United States)

Lightbody, Amy A.; Reiss, Allan L.

2009-01-01

Fragile X syndrome (FraX) remains the most common inherited cause of intellectual disability and provides a valuable model for studying gene-brain-behavior relationships. Over the past 15 years, structural and functional magnetic resonance imaging studies have emerged with the goal of better understanding the neural pathways contributing to the…

A study on relationship between quality of work life and job satisfaction

Directory of Open Access Journals (Sweden)

Heydar Mohammadi

2013-10-01

Full Text Available A healthy and good work condition is often involved with other factors such as leadership style, management, etc. In this paper, we present an empirical investigation to study the effects of the quality of work life on job satisfaction. The study uses a standard questionnaire and distributes it among all 86 full time employees of two governmental agencies in Iran, Supreme Audit Court and Interior Ministry, and Cronbach alphas has been calculated as 0.92. The main hypothesis of this survey considers the relationship between job satisfaction and quality of work life and there. There are also eleven sub-hypotheses associated with this survey including fair and sufficient payment, safe and healthy work conditions, equal job opportunities, rule of law, service training, integration and social cohesion, human development capabilities, organizational structure, delegation of authority, job satisfaction and employee participation. The results of survey have confirmed that there were some meaningful relationships between the quality of work life on job satisfaction in both organizations.

Exploring the relationship between convenience and fish consumption: a cross-cultural study.

Science.gov (United States)

Olsen, Svein Ottar; Scholderer, Joachim; Brunsø, Karen; Verbeke, Wim

2007-07-01

The purpose of the present study is to explore cultural differences in the meaning of convenience and the relationships between convenience, attitudes and fish consumption in five European countries. The results suggest that the meaning of meal convenience is not culture specific, whilst the absolute levels of convenience orientation and the perceived inconvenience of fish differ between cultures. Convenience orientation was highest in Poland, followed by Spain, and was lowest in the Netherlands. The relationships between convenience orientation and attitudes towards fish, and convenience orientation and fish consumption, were insignificant in most countries. However, convenience orientation was positively related to the perceived inconvenience of fish. Perceived inconvenience of fish was negatively related to both attitudes towards fish and to fish consumption. Together, these results confirm some earlier findings that fish is generally perceived as a relatively inconvenient type of food. This study suggests that convenience orientation can be crucial to understanding food choice or behaviour only when critical mediating constructs are explored.

Multi-wavelength spectrophotometric determination of acidity constant of some newly synthesized Schiff bases and their QSPR study

Science.gov (United States)

Hemmateenejad, Bahram; Emami, Leila; Sharghi, Hashem

2010-01-01

The acidity constants of some newly synthesized Schiff base derivatives were determined by hard-model based multivariate data analysis of the spectrophotometric data in the course of pH-metric titration in 50% (v/v) methanol-water binary solvent. The employed data analysis method was also able to extract the pure spectra and pH-dependent concentration profiles of the acid-base species. The molecules that possess different substituents (both electron donating and withdrawing) on the ortho-, meta- and para-positions of one of the phenyl ring showed variable acidity constants ranging from 8.77 to 11.07 whereas the parent molecule had an acidity constant of 10.25. To investigate the quantitative effects of changing of substitution pattern on the acidity constant, a quantitative structure-property relation analysis was conducted using substituent constants and molecular descriptor. Some models with high statistical quality (measured by cross-validation Q2) were obtained. It was found that the acidity constant of the studied molecules in the methanol-water mixed solvent not only is affected by electronic features of the solutes but also by the lipophilic interaction between methanol part of solvent and the deprotonated solutes.

Strategic logistics service provider selection influenced by relationships, cost and market dynamics - a multi-factorial case study

DEFF Research Database (Denmark)

Tambo, Torben

2012-01-01

Selection of logistics service providers (LSPs) is regarded critical and complex. Relationships tend to last for many years and have a critical role in the architecting of supply chains. Occasionally, relationships between buyer and LSP come to a crossroad of termination, extension or change......; attrition of relationships can be caused by poor quality, changed market conditions, changed management, changed operational conditions on either side, and moves from competitors. This study uses a case-based methodology to provide an in-depth account of business motivations in relationship development...... in LSP selection. The study presents a tendering process as a fulcrum of "non-conformant‟ behaviour and unexpected outcome. Major findings are that contract-bound services and cost structures seem to drift into less transparent and informal patterns of interactions over time; this is wearing...

A study on relationship between empowering employees and social capital depreciation: A case study of treasury department

Directory of Open Access Journals (Sweden)

Manouchehr Rahmdel

2013-10-01

Full Text Available Empowering employee plays essential role in having sustainable social capital. When social capital is depreciated, we may expect some negative consequences on society and working environment. Therefore, we need to investigate different factors influencing depreciation of social capital as well as empowering employees. The proposed model of this paper designs a questionnaire and distributes it among some randomly selected employees who worked for treasury department in Iran. The study uses two regression models, where empowering employees is a function of four independent variables including being effective, having the right to select, competency and being meaningful. The other regression model studies the relationship between depreciation of employee as dependent variable and four independent variables including job involvement, television, living affairs and generation change. The results of both regression analyses indicate that there were some positive and meaningful relationship between empowering employees as well as depreciation of employees as dependent variable and independent variables.

Constraints and Dedication as Drivers for Relationship Commitment: An Empirical Study in a Health-Care Context

NARCIS (Netherlands)

Odekerken-Schröder, G.J.; Bloemer, J.M.M.

2002-01-01

The objective of this study is to empirically determine the role of constraints and dedication as drivers of relationship commitment as most of the existing work is of a conceptual nature only. We assess how and to which extent these two drivers fit into the established relationships between overall

Project STARS (Studies on Trajectories of Adolescent Relationships and Sexuality) : A longitudinal, multidomain study on sexual development of Dutch adolescents

NARCIS (Netherlands)

Reitz, Ellen; van de Bongardt, Daphne; Baams, Laura; Doornwaard, Suzan; Dalenberg, Wieke; Dubas, Judith; van Aken, Marcel; Overbeek, Geertjan; ter Bogt, Tom; van der Eijnden, Regina; Vanwesenbeeck, Ine; Kunnen, Saskia; Timmerman, Greetje; van Geert, Paul; Dekovic, Maja

2015-01-01

This study gives an overview of Project STARS (Studies on Trajectories of Adolescent Relationships and Sexuality), a four-wave longitudinal study of 1297 Dutch adolescents. First, the sample, measures and four sub-projects are described. Second, hierarchical regression analyses were conducted to

Augmentation index (AI) in a dose-response relationship with smoking habits in males: The Tanushimaru study.

Science.gov (United States)

Tsuru, Tomoko; Adachi, Hisashi; Enomoto, Mika; Fukami, Ako; Kumagai, Eita; Nakamura, Sachiko; Nohara, Yume; Kono, Shoko; Nakao, Erika; Sakaue, Akiko; Morikawa, Nagisa; Fukumoto, Yoshihiro

2016-12-01

We investigated the relationship between augmentation index (AI) and smoking habits in community-dwelling Japanese.This cross-sectional study enrolled 1926 subjects (769 males and 1157 females) aged 40 to 95 years who underwent a health check-up in a Japanese cohort of the Seven Countries Study, in Tanushimaru, a typical farming town in Kyushu Island in 2009. The subjects' medical history, alcohol intake, smoking habit, and current medications for hypertension, dyslipidemia, and diabetes were ascertained by questionnaire. Radial arterial pressure wave analysis was used to obtain AI. We analyzed the data stratified by gender.Age-adjusted means of AI in males showed a clear dose-response relationship in 4 categories of smoking habits (P = 0.010). There was no significant relationship between AI and smoking habits in females (P = 0.127). The significant dose-response relationship (P = 0.036) in males between AI and 4 categories of smoking habits still remained even after adjustment for age, body mass index, systolic blood pressure, estimated glomerular filtration rate, glucose, hypertensive medication, and alcohol intake.The present study demonstrated that AI values were significantly associated with smoking habits in a dose-dependent manner in Japanese males.

Exploring the Relationship between Writing Apprehension and Writing Performance: A Qualitative Study

Science.gov (United States)

Badrasawi, Kamal J. I.; Zubairi, Ainol; Idrus, Faizah

2016-01-01

Writing skill is seen as a cornerstone of university students' success in both academic and career life. This qualitative study was conducted to further explore the teachers' and students' perceptions on the relationship between writing apprehension and writing performance, contributing factors of writing apprehension, and strategies to reduce…

Designing and Maintaining a Communication Consulting Relationship: A Fire Officer Case Study

Science.gov (United States)

Cragan, John F.

2008-01-01

This case study describes a 35-year communication consulting relationship with the Illinois Fire Chiefs' Association. This case explains the fire chiefs' educational problems, the five-step method for creating an educational curriculum for fire officers, and the five-step procedure for continuous evaluation of the curriculum. Finally, an…

The Study of Relationship between Organizational Learning and Organizational Performance

Directory of Open Access Journals (Sweden)

Bisotoon Azizi

2017-01-01

Full Text Available The aim of this study was to investigate the relationship between organizational learning and organizational performance among companies operating in the insurance industry of Tehran in Iran. The present study is a descriptive one in terms of the purpose and the method of data collection. The statistical population of the study was all insurance companies in the city of Tehran and 120 insurance companies were selected due to the lack of detailed statistical reference to their number. For this purpose, people were asked some questions who it was authorized to represent the name. The questionnaire is a tool for collecting data. The Gomez questionnaire et al. (2005 was used to measure organizational learning which includes four factors: management commitment, system perspective, openness and experimentation, transfer and integration of knowledge. To measure the organizational performance, the Yang et al. questionnaire (2004 is used. To determine the validity of data collection, the questionnaire was presented to six professors of management at various universities. The validity of questionnaire through the coordination of jury was about %100. The reliability of the questionnaire was conducted on thirty subjects, Cronbach alpha coefficient was calculated 0.91 and 0.85 for organizational learning and organizational performance, respectively. For data analysis, Pearson correlation coefficient and multiple regressions were used. The results showed that there is a positive relationship between organizational learning and its four dimensions (management commitment, vision systems, open space, and experimentation, transfer and integration of knowledge and organizational performance of Tehran insurance companies.

Uncovering nursing students' views of their relationship with educators in a university context: A descriptive qualitative study.

Science.gov (United States)

Chan, Zenobia C Y; Tong, Chien Wai; Henderson, Saras

2017-02-01

Power dynamics is a key element in the educator-student relationship, and can be influential to the learning outcomes of students. Power relations are inherent in the interaction between educators and students. The educator-student relationship is still an under-explored area of power dynamics. The aim of the study was to investigate nursing students' perceptions of the power dynamics in the educator-student relationship in a university learning context in order to offer educators some understanding of how such a relationship was perceived by students. A descriptive qualitative study using focus group inquiry. Through convenience sampling, a total of 56 students were recruited and eight focus group interviews were conducted. Thematic analysis was adopted to capture the meanings extracted from the student narratives. Four core themes of the educator-student relationship were identified. Referring to these themes, some implications were drawn, such as the significance of the educator-student relationship; an educator's power matters; and polarized views among the students on whether or not an educator should be a friend. The power dynamics varied depending on an educator's personality, communication skills, ability to effectively monitor large classes, and teaching style. More efforts are needed to investigate the preferred conceptions and types of educator-student relationships in order to evaluate the impact that these have on learning. Copyright © 2016 Elsevier Ltd. All rights reserved.

Impact of Relationship Status and Quality (Family Type) on the Mental Health of Mothers and Their Children: A 10-Year Longitudinal Study.

Science.gov (United States)

Hannighofer, Jasmin; Foran, Heather; Hahlweg, Kurt; Zimmermann, Tanja

2017-01-01

Mothers and children of single or unstable relationships have higher rates of mental health problems than those in stable two-parent families. Despite results that mothers and children of conflictual two-parent families also show impairments, most studies do not consider relationship quality. Therefore, the present study combines relationship status and relationship quality to a "family type." The present study compares German mothers and children of two-parent families with high relationship quality to those from two-parent families with a low quality, single mothers, and unstable families. Data of n  = 249 families from a 10-year follow-up longitudinal study show that mothers with a high relationship quality show the highest levels of mental health whereas all other groups show at least a 3.2 times higher probability of mental health symptoms. Children of mothers in unstable relationships show a 8.2 times higher probability to emotional or behavioral problems than children of mothers with high relationship quality. Therefore, not only relationship status but also relationship quality should be combined and this "family type" should be considered in future research.

A Qualitative Study into Dependent Relationships and Voluntary Informed Consent for Research in Pediatric Oncology.

Science.gov (United States)

Dekking, Sara A S; van der Graaf, Rieke; Schouten-van Meeteren, Antoinette Y N; Kars, Marijke C; van Delden, Johannes J M

2016-04-01

In pediatric oncology, many oncologists invite their own patients to participate in research. Inclusion within a dependent relationship is considered to potentially compromise voluntariness of consent. Currently, it is unknown to what extent those involved in pediatric oncology experience the dependent relationship as a threat to voluntary informed consent, and what they see as safeguards to protect voluntary informed consent within a dependent relationship. We performed a qualitative study among key actors in pediatric oncology to explore their experiences with the dependent relationship and voluntary informed consent. We conducted three focus groups and 25 semi-structured, in-depth interviews with pediatric oncologists, research coordinators, Research Ethics Committee members, parents of children with cancer, and adolescents with cancer. Professionals regarded the dependent relationship both as a potential threat to and as a positive influence on voluntary decision making. Parents and adolescents did not feel as though dependency upon the oncologist influenced their decisions. They valued the involvement of their own physician in the informed consent process. The professionals suggested three strategies to protect voluntariness: emphasizing voluntariness; empowering families; involvement of an independent person. Although the dependent relationship between pediatric oncologists, patients and parents may be problematic for voluntary informed consent, this is not necessarily the case. Moreover, the involvement of treating physicians may even have a positive impact on the informed consent process. Although we studied pediatric oncology, our results may also apply to many other fields of pediatric medicine where research and care are combined, for example, pediatric rheumatology, neurology and nephrology. Clinical trials in these fields are inevitably often designed, initiated and conducted by medical specialists closely involved in patient care.

The Viewpoints of Sexually Active Single Women About Premarital Sexual Relationships: A Qualitative Study in the Iranian Context

Science.gov (United States)

Rahmani, Azam; Merghati-Khoei, Effat; Moghaddam-Banaem, Lida; Hajizadeh, Ebrahim; Montazeri, Ali

2016-01-01

Background: Premarital sexual relationships could harm youth’s health in terms of sexually transmitted infections or increased risk of unprotected sexual behaviors. Sexual abstinence has been recommended to prevent young adolescents from adverse outcomes of premarital sexual relationships. Objectives: The aim of this study was to explore the viewpoints of sexually active single women about premarital sexual relationships in the Iranian context. Patients and Methods: In this qualitative study, we recruited 41 young women aged 18 to 35 years. Data were collected using focus group discussions and individual interviews. We employed conventional content analysis to analyze the data. Multiple data collection methods, maximum variation sampling, and peer checks were applied to enhance the reliability of the findings. Results: Eight themes emerged from the data analysis: ‘acceptance of sexual contact in the context of opposite-sex relationships, ‘sexual activity as a guarantee for keeping the boyfriend in the relationship’, ‘premarital sexual relationship as an undeniable personal right’, ‘having successful marriage in spite of premarital sexual relationships’, ‘virginity as an old fashioned phenomenon’, ‘love as a license for premarital sexual behaviors’, ‘goal-oriented relationship as a license for premarital sexual behaviors’, and ‘experiencing premarital sexual relationships in order to gain perfection’. Conclusions: Results of this study could be applied to designing interventions, such as promotion of preventive beliefs or educational programs regarding premarital sexual relationships in conservative societies. These interventions could start within families and continue at schools and universities. PMID:27162757

Early Relationship Quality from Home to School: A Longitudinal Study.

Science.gov (United States)

Vondra, Joan I.; Shaw, Daniel S.; Swearingen, Laure; Owens, Elizabeth B.; Cohen, Meredith

1999-01-01

Examined role of home social relationships as predictors of social functioning in first years of school. Found that the quality of different family relationships provided relatively independent and complementary information about early social functioning in school, with more limited evidence for compensatory or protective processes at work.…

Associations of Bariatric Surgery With Changes in Interpersonal Relationship Status: Results From 2 Swedish Cohort Studies.

Science.gov (United States)

Bruze, Gustaf; Holmin, Tobias E; Peltonen, Markku; Ottosson, Johan; Sjöholm, Kajsa; Näslund, Ingmar; Neovius, Martin; Carlsson, Lena M S; Svensson, Per-Arne

2018-03-28

Bariatric surgery is a life-changing treatment for patients with severe obesity, but little is known about its association with interpersonal relationships. To investigate if relationship status is altered after bariatric surgery. Changes in relationship status after bariatric surgery were examined in 2 cohorts: (1) the prospective Swedish Obese Subjects (SOS) study, which recruited patients undergoing bariatric surgery from September 1, 1987, to January 31, 2001, and compared their care with usual nonsurgical care in matched obese control participants; and (2) participants from the Scandinavian Obesity Surgery Registry (SOReg), a prospective, electronically captured register that recruited patients from January 2007 through December 2012 and selected comparator participants from the general population matched on age, sex, and place of residence. Data was collected in surgical departments and primary health care centers in Sweden. The current analysis includes data collected up until July 2015 (SOS) and December 2012 (SOReg). Data analysis was completed from June 2016 to December 2017. In the SOS study, information on relationship status was obtained from questionnaires. In the SOReg and general population cohort, information on marriage and divorce was obtained from the Swedish Total Population Registry. The SOS study included 1958 patients who had bariatric surgery (of whom 1389 [70.9%] were female) and 1912 matched obese controls (of whom 1354 [70.8%] were female) and had a median (range) follow-up of 10 (0.5-20) years. The SOReg cohort included 29 234 patients who had gastric bypass surgery (of whom 22 131 [75.6%] were female) and 283 748 comparators from the general population (of whom 214 342 [75.5%] were female), and had a median (range) follow-up of 2.9 (0.003-7.0) years. In the SOS study, the surgical patients received gastric banding (n = 368; 18.8%), vertical banded gastroplasty (n = 1331; 68.0%), or gastric bypass (n = 259; 13

Exploring the relationship between convenience and fish consumption: A cross-cultural study

DEFF Research Database (Denmark)

Olsen, Svein Ottar; Scholderer, Joachim; Brunsø, Karen

2007-01-01

The purpose of the present study is to explore cultural differences in the meaning of convenience and the relationships between convenience, attitudes and fish consumption in five European countries. The results suggest that the meaning of meal convenience is not culture specific, whilst...... the absolute levels of convenience orientation and the perceived inconvenience of fish differ between cultures. Convenience orientation was highest in Poland, followed by Spain, and was lowest in the Netherlands. The relationships between convenience orientation and attitudes towards fish, and convenience...... orientation and fish consumption, were insignificant in most countries. However, convenience orientation was positively related to the perceived inconvenience of fish. Perceived inconvenience of fish was negatively related to both attitudes towards fish and to fish consumption. Together, these results confirm...

Study on the relationship between project management and organizational efficacy in nonprofit organizations

Directory of Open Access Journals (Sweden)

Kao I-Chan

2018-01-01

Full Text Available This study treats the members in nonprofit organizations (NPOs as subjects, and explores the origination, planning, control, and completion of project management in NPOs, as well as the general performance of organizational efficacy, such as environmental satisfaction, organizational atmosphere, operational performance, job engagement, and work quality. It also probes into the relationship and effect. By various research methods, such as literature review and questionnaire survey, this study attempts to determine if project management in NPOs can significantly enhance organizational efficacy. This study finds that different NPOs have significant differences in the general performance of project management and organizational efficacy. When the performance of project management in NPOs is more significant, organizational efficacy is higher. Project management in NPOs has a significant path relationship to organizational efficacy; therefore, reinforcement of vocational training in the project management of NPOs could improve performance, which would have significant effect on enhancing organizational efficacy.

Radioactive zinc in soil-plant relationship studies

International Nuclear Information System (INIS)

Karimian, N.

1986-01-01

Zinc is one of the elements whose essentiality for plant growth and development has been proved beyond any doubt. Plant life and consequently the crop yield is impossible without zinc. The results of chemical, greenhouse, and field experiments on soils of Shiraz show that their level of available zinc for some crops is inadequate, despite the fact that the total amount of zinc in these soils may be relatively high. Obtaining the maximum yield, therefore, requires that either supplemental zinc be applied as chemical fertilizers or make the endogenous zinc more available to plants through some management practices. One of the isotopes of zinc, i.e. 65 Zn, is radioactive and has a detectable radiation which makes it suitable for tracer studies of zinc in soil, water, plant and animal. These studies help in understanding the soil plant relationships of zinc which in turn help to determine the optimum conditions of obtaining maximum yield. This paper presents and analyzes the results of some selected experiments to show different techniques of using radioactive zinc in understanding the behavior of zinc in soil and plant. Suggestions are also made of using this radioisotope in understanding the reactions of zinc in soils of Iran

Relationship satisfaction in women: A longitudinal case-control study about the role of breast cancer, personal assertiveness and partner's relationship-focused coping. : A longitudinal case-control study about the role of breast cancer, personal assertiveness, and partners' relationship-focused coping

NARCIS (Netherlands)

Hinnen, C.; Hagedoorn, M.; Ranchor, A.V; Sanderman, R.

2008-01-01

Objective. The aim of this study was to investigate whether a breast cancer diagnosis, personal assertiveness (i.e. frequency of assertive behaviour and tension associated with this behaviour), and partners' relationship-focused coping (i.e. active engagement and protective buffering) were sources

Establishing Respectful Educative Relationships: A Study of Newly Qualified Teachers in Ireland

Science.gov (United States)

O'Grady, Emmanuel

2015-01-01

Interpersonal respect is a fundamental aspect of relating to others. This is especially true for teachers, as cultivating relationships is implicit in effective teaching. This three-year qualitative study examines a developing understanding of respect for pre-service teachers that progresses on to their first year's teaching to examine the…

An empirical study of the relationship between restaurant image and customer loyalty

OpenAIRE

Oh, Heung Chul

1995-01-01

The primary objective of this study was to empirically determine the relationship between restaurant images and loyalties toward seven competing casual dinner house restaurant chains, and to understand the nature of their competition by matching patronage behavior toward alternative restaurant chains with perceptions of alternative restaurants on particular image attributes.

Relationship between mental health and spiritual wellbeing among hemodialysis patients: a correlation study

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Beatriz Bertolaccini Martinez

Full Text Available CONTEXT AND OBJECTIVE: The stress of living with a terminal disease has a negative impact on the mental health of hemodialysis (HD patients. Spirituality is a potential coping mechanism for stressful experiences. Studies on the relationship between spirituality and mental health among HD patients are scarce. The purpose of this study was to evaluate the relationship between mental health and spiritual well-being among HD patients. DESIGN AND SETTING: Cross-sectional observational study on hemodialysis patients at a single center in Brazil, between January and December 2011. METHODS : Mental health was assessed using the General Health Questionnaire and spiritual wellbeing was assessed using the Spiritual Wellbeing Scale; 150 HD patients participated in the study. RESULTS : A significant correlation was found between mental health and spiritual wellbeing (P = 0.001. Spiritual wellbeing was the strongest predictor of mental health, psychological distress, sleep disturbance and psychosomatic complaints. CONCLUSION: Poor mental health was associated with lower spiritual wellbeing. This has important implications for delivery of palliative care to HD patients.

A Study on the Relationship of Earnings and Cash Flows: Evidence of Finance Sector in Iran

OpenAIRE

Mahdi Salehi; Mirsohrab Seyedghorbani

2013-01-01

The present study is investigating the quality of annual accounting earnings in banking firms that have been listed in Tehran Stock Exchange (TSE) and it evaluates the most important information of accounting that is earnings and cash flows. The study also intends to investigate the relationship between earnings and cash flows regarding their relationship with the expected return of stocks and the extent of informing in the analysis of the inevitable return of stocks. The analyses of data dur...

Affctionate Relationships With Brands: Study of the Consequences of Brand Love with Summer Festivals

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Vasco Eiriz

2016-09-01

Full Text Available This article focus on the concept o brand love, a kind of affectionable, deep and lasting relationship established between consumers and brands, which results in beneficial consequences for firms. Having in mind the growing importance of services and the lack of studies on brand love in the service context, this research defined as object of study the summer festivals in Portugal, major music and entertaining events based on strong brands. More specifically, this article diagnosis the concept of brand love and it identifies the consequences of that consumers' love with summer festivals. It was carried out a questionnaire to the consumers of the main summer festivals in Portugal, which obtained 349 responses. The results show that the word-of-mouth and the active participation of consumers are the main consequences of this kind of relationship based on brand love, while loyalty and willingness to pay a premium-price are less evident consequences. The results of this study suggest that it is essential that brands create emotional bonds with consumers aiming at the developing of brand love. This kind of relationship that causes consumers' active participation and word-of-mouth imply that consumers behave as brand ambassadors, allowing brands to strength its competitive position.

Relationships between eating quickly and weight gain in Japanese university students: a longitudinal study.

Science.gov (United States)

Yamane, Mayu; Ekuni, Daisuke; Mizutani, Shinsuke; Kataoka, Kota; Sakumoto-Kataoka, Masami; Kawabata, Yuya; Omori, Chie; Azuma, Tetsuji; Tomofuji, Takaaki; Iwasaki, Yoshiaki; Morita, Manabu

2014-10-01

Many cross-sectional studies have reported a relationship between overweight/obesity and eating quickly, but there have been few longitudinal studies to address this relationship in younger populations. The purpose of this prospective longitudinal study was to investigate whether eating quickly was related to being overweight in Japanese university students. Of 1,396 students who underwent a general examination and completed questionnaires at the start of university and before graduation, 1,314 students (676 male and 638 female) of normal body composition [body mass index (BMI) students whose BMIs were ≥ 25 kg m(-2) were defined as overweight. In this study, 38 participants (2.9%) became overweight. In the logistic regression analysis, the risk of being overweight was increased in males [adjusted odds ratio (OR): 2.77; 95% confidence interval (CI): 1.33-5.79; P university students. Copyright © 2014 The Obesity Society.

The relationship between individualized care and the practice environment: an international study.

Science.gov (United States)

Papastavrou, Evridiki; Acaroglu, Rengin; Sendir, Merdiye; Berg, Agneta; Efstathiou, Georgios; Idvall, Ewa; Kalafati, Maria; Katajisto, Jouko; Leino-Kilpi, Helena; Lemonidou, Chryssoula; da Luz, Maria Deolinda Antunes; Suhonen, Riitta

2015-01-01

Previous research studies have found that the better the quality of practice environments in hospitals, the better the outcomes for nurses and patients. Practice environment may influence nurses' ability to individualize care but the detailed relationship between individualized care and the professional practice environment has not been investigated widely. Some evidence exists about the association of practice environments with the level of individualization of nursing care, but this evidence is based on single national studies. The aim of this study was to determine whether nurses' views of their professional practice environment associate with their views of the level of care individualization in seven countries. This study had an international, multisite, prospective, cross-sectional, exploratory survey design. The study involved acute orthopedic and trauma surgical inpatient wards (n=91) in acute care hospitals (n=34) in seven countries, Cyprus, Finland, Greece, the State of Kansas, USA, Portugal, Sweden, and Turkey. Nurses (n=1163), registered or licensed practical, working in direct patient care, in orthopedic and trauma inpatient units in acute care hospitals in seven countries participated in the study. Self-administered questionnaires, including two instruments, the Revised Professional Practice Environment and the Individualized Care Scale-Nurse (Individualized Care Scale-Nurse A and B) were used for data collection. Data were analyzed statistically using descriptive statistics, simultaneous multiple regression analysis, and generalized linear model. Two regression models were applied to assess the predictive validity of the Revised Professional Practice Environment on the Individualized Care Scale-Nurse-A and B. The results showed that elements of the professional practice environment were associated with care individualization. Internal work motivation, cultural sensitivity, control over practice, teamwork, and staff relationship with physicians were

The influence of length of relationship, gender and age on the relationship intention of short-term insurance clients: an exploratory study

Directory of Open Access Journals (Sweden)

Derik Steyn

2011-09-01

insurance industry completed self-administered questionnaires. Findings indicate that, for a group of high relationship-intention clients of a short-term insurance organisation, no practically significant discrimination exists on any of the relationship-intention constructs for clients’ length of relationship, gender or age.

The Multifold Relationship between Memory and Decision Making: An Individual-Differences Study

Science.gov (United States)

Del Missier, Fabio; Mäntylä, Timo; Hansson, Patrik; Bruine de Bruin, Wändi; Parker, Andrew M.; Nilsson, Lars-Göran

2013-01-01

Several judgment and decision-making tasks are assumed to involve memory functions, but significant knowledge gaps on the memory processes underlying these tasks remain. In a study on 568 adults between 25 and 80 years of age, hypotheses were tested on the specific relationships between individual differences in working memory, episodic memory,…

Impact of Relationship Status and Quality (Family Type on the Mental Health of Mothers and Their Children: A 10-Year Longitudinal Study

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Jasmin Hannighofer

2017-11-01

Full Text Available Mothers and children of single or unstable relationships have higher rates of mental health problems than those in stable two-parent families. Despite results that mothers and children of conflictual two-parent families also show impairments, most studies do not consider relationship quality. Therefore, the present study combines relationship status and relationship quality to a “family type.” The present study compares German mothers and children of two-parent families with high relationship quality to those from two-parent families with a low quality, single mothers, and unstable families. Data of n = 249 families from a 10-year follow-up longitudinal study show that mothers with a high relationship quality show the highest levels of mental health whereas all other groups show at least a 3.2 times higher probability of mental health symptoms. Children of mothers in unstable relationships show a 8.2 times higher probability to emotional or behavioral problems than children of mothers with high relationship quality. Therefore, not only relationship status but also relationship quality should be combined and this “family type” should be considered in future research.

A Study of Online Misrepresentation, Self-Disclosure, Cyber-Relationship Motives, and Loneliness among Teenagers in Taiwan

Science.gov (United States)

Huang, Chiao Ling; Yang, Shu Ching

2013-01-01

The purpose of this study was to investigate the relationships between online misrepresentation (OM), self-disclosure (SD), cyber-relationship motives (CRM), and loneliness in teenagers. A survey was conducted using a sample of 608 Taiwanese teenagers (13 to 18 years of age). The instruments used include scales of loneliness, OM, and SD in real…

The Role of Talent Management in the Relationships between Employee Engagement: A Study of GLCs

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Aizat Ramli Afdzal

2018-01-01

Full Text Available Talent management practice is crucial in relating the potential talent. The GLCs need to have a potential talent in order to continue the value creation for business competitiveness. Moreover, talent that possesses high level of commitment and engagement will add value in the organization. This study aims to examine the relationship between talent management practices and employee engagement of employees at GLCs. The sample included 230 employees, which were selected randomly. For this study the method for data collection uses a structured questionnaire and were analyzed using partial least square. The hypothesis in this study is accepted whereby on the empirical evidences, it proves the relationship between talent management practices and employee engagement‥

Structure-activity relationship studies of the aromatic positions in cyclopentapeptide CXCR4 antagonists

DEFF Research Database (Denmark)

Mungalpara, Jignesh; Zachariassen, Zack G; Thiele, Stefanie

2013-01-01

, and autoimmune diseases. While the structure-activity relationships for Arg(1), Arg(2), and Gly(4) are well established, less is understood about the roles of the aromatic residues 2-Nal(3) and D-Tyr(5). Here we report further structure-activity relationship studies of these two positions, which showed that (i......) the distal aromatic ring of the 2-Nal(3) side chain is required in order to maintain high potency and (ii) replacement of D-Tyr(5) with conformationally constrained analogues results in significantly reduced activity. However, a simplified analogue that contained Gly instead of D-Tyr(5) was only 13-fold less...

Perception of Work, Relationships and Career: A Study with Undergraduate Students

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Fábio Nogueira Pereira

2011-06-01

Full Text Available This study researched how a population of 40 undergraduate students attending a career planning project in a private college perceived work, career and their relation with interpersonal relationships. The questionnaire revealed that most subjects perceived work positively, reported through four different perceptions of work, reported perceiving a social dimension of work, but about half of it reported that they didn’t perceive people in general working in a way that showed being concerned about changing society. When the subjects listed people who worked with the same values they held, reports ranged through parents, bosses and friends; when asked about people that didn’t have the same values, they listed work-mates, peers and siblings; when asked about most important people for their career, they listed their parents separately, teachers and children. Data suggested a wide participation of relationships in processing information and constructing conceptions related to work and career.

Job satisfaction and teacher-student relationships across the teaching career : Four case studies

NARCIS (Netherlands)

Veldman, Ietje; van Tartwijk, Jan; Brekelmans, Mieke; Wubbels, Theo

2013-01-01

We studied the development of teacher-student relationships and teachers' job satisfaction throughout the careers of four veteran teachers who retained high job satisfaction. Teacher data gathered with the narrative-biographical method were compared with students' perceptions of the teacher-student

Study on the relationship between SLE and the related serum hormone

International Nuclear Information System (INIS)

Lu Yun; Deng Shouzhen; Lin Xiangtong; Feng Shufang; Xu Jinhua; He Wanting; Zhang Guangming; Cheng Wei; Gao Quan

1998-01-01

To explore the relationship between PRL, GH(RIA), GH(RRA) serum levels changes and the onset and development of disease in patients with SLE, and to understand the hormonal changes in active and inactive phase of disease, 28 cases and 20 controls were studied. The results showed that anti-ds-DNA serum level in active and inactive phases was higher than those in controls (P 1 2 <0.05). This study indicated that the higher serum level of PRL, GH(RIA), GH(RRA) is correlated with some autoimmune characteristics of SLE, especially in its active phase. Therefore it gives some help for clinical study of SLE

Relationships between body image, sexual satisfaction, and relationship quality in romantic couples.

Science.gov (United States)

van den Brink, Femke; Vollmann, Manja; Smeets, Monique A M; Hessen, David J; Woertman, Liesbeth

2018-03-08

Previous studies found important associations between body image, sexual satisfaction, and perceived romantic relationship quality, but mainly focused on one individual's perceptions rather than both partners. To take the interdependency of romantic partners into account, the present study examined these associations in romantic couples with a dyadic approach. In a cross-sectional design, 151 Dutch heterosexual couples completed an online survey measuring body image, sexual satisfaction, and perceived relationship quality. Hypotheses were tested using the actor-partner interdependence model (APIM) and an APIM extended with a mediator (APIMeM), with couple members' body image as predictors, couple members' sexual satisfaction as mediators, and couple members' relationship quality as outcomes. Results indicated that within individuals, a more positive body image was linked to higher perceived romantic relationship quality through greater sexual satisfaction. No gender differences were found, implying that body image and sexual satisfaction are equally strongly associated with perceived relationship quality in women and men. Results revealed no associations of an individual's body image and sexual satisfaction with the partner's perceived relationship quality. These findings implicate that interventions focusing on developing and maintaining a positive body image may be helpful in building on a more satisfying sex life and higher perceived relationship quality. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Are narcissists more attracted to people in relationships than to people not in relationships?

Science.gov (United States)

Okdie, Bradley M.

2018-01-01

Does grandiose narcissism predict greater attraction for others in relationships? We examined this question by replicating previous work implicating grandiose narcissists as mate poachers (Studies 1 and 2). We then used an experimental paradigm (Studies 3 and 4) to assess the extent to which grandiose narcissists indicate a greater interest in someone who is already in a relationship compared to someone who is single. Results suggest that although grandiose narcissism related to reports of more frequent mate poaching attempts, grandiose narcissists did not appear to be more interested in taking someone away from an existing relationship. Instead, participants took their own relationship status into consideration (rather than the relationship status of a target) when evaluating their interest in a target for a short-term fling or a long-term relationship. Thus, although grandiose narcissists report more frequent mate poaching attempts, they do not appear to be more interested in people in relationships compared to those who are single. PMID:29584747

Are narcissists more attracted to people in relationships than to people not in relationships?

Science.gov (United States)

Brunell, Amy B; Robison, Joshua; Deems, Nicholas P; Okdie, Bradley M

2018-01-01

Does grandiose narcissism predict greater attraction for others in relationships? We examined this question by replicating previous work implicating grandiose narcissists as mate poachers (Studies 1 and 2). We then used an experimental paradigm (Studies 3 and 4) to assess the extent to which grandiose narcissists indicate a greater interest in someone who is already in a relationship compared to someone who is single. Results suggest that although grandiose narcissism related to reports of more frequent mate poaching attempts, grandiose narcissists did not appear to be more interested in taking someone away from an existing relationship. Instead, participants took their own relationship status into consideration (rather than the relationship status of a target) when evaluating their interest in a target for a short-term fling or a long-term relationship. Thus, although grandiose narcissists report more frequent mate poaching attempts, they do not appear to be more interested in people in relationships compared to those who are single.

The Relationship Between Intellectual Capital and Firm Value: A Study in Istanbul Stock Exchange

Directory of Open Access Journals (Sweden)

Selim CENGİZ

2013-06-01

Full Text Available The main purpose of this study is to investigate the relationship between intellectual capital and firm value. The study is significant in that it makes intellectual capital, which is of vital importance in ensuring firms’ sustainability, more apparent and it provides a chance to make comparisons with other studies. The companies operating in energy sector in Borsa Istanbul (abbreviated as BIST, former Istanbul Stock Exchange during the period of 2009-2011, are taken into the scope of analysis. Within this scope, the findings obtained by using “Calculated Intangible Value Management” are compared with firms’ market value/book value practices in order to determine the relationship between intellectual capital and firm value. The findings reveal that energy companies operating in Turkey do not consider their intellectual capital assets important and tangible assets are the main factors affecting business performance.

Prediction of Surfactants’ Properties using Multiscale Molecular Modeling Tools: A Review Prédiction de propriétés des tensioactifs à l’aide d’outils de modélisation moléculaire : une revue

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Creton B.

2013-01-01

Full Text Available During one of the existing Enhanced Oil Recovery (EOR procedures, a mixture of Alkaline/Surfactant/Polymer (ASP is injected into wells in order to move the trapped oil from the reservoir to the wellbores. The conception and/or the tuning of new ASP combinations, structures of surfactants and/or mixtures of surfactants is of primary interest to improve the efficiency of a such procedure. Molecular modeling tools can be used to understand microscopic effects, predict surfactants’ properties and finally to optimize structures and mixtures of surfactants. We propose in this article a review of the literature on the ability of molecular simulation techniques such as Molecular Dynamics (MD, Monte Carlo (MC simulations, Dissipative Particle Dynamics (DPD and upper scale modeling methods such as Quantitative Structure-Property Relationship (QSPR approaches to predict thermo-physical and structural properties of surfactants. Une des voies possibles de récupération assistée du pétrole, l’EOR (Enhanced Oil Recovery, consiste en l’injection d’un fluide ASP (Alkaline/Surfactant/Polymer dans le réservoir dans le but de déplacer le pétrole piégé vers le puits de production. La conception et/ou l’optimisation de mélanges ASP, de tensioactifs ou de mélanges de tensioactifs est donc d’un intérêt premier pour améliorer l’efficacité d’un tel procédé. Les codes de simulation moléculaire développés et largement validés durant ces dernières décennies apparaissent comme des outils incontournables pour la compréhension des effets microscopiques, la prédiction de propriétés de tensioactifs complexes ou encore l’optimisation des structures voire de la composition de mélanges de tensioactifs. Dans cet article, nous présentons une revue des travaux de la littérature sur le potentiel de diverses techniques de simulation moléculaire pour la prédiction de propriétés structurales ou thermophysiques des tensioactifs. Les

Relationship Quality Time: The Validation of a Relationship Quality Scale in Higher Education

Science.gov (United States)

Snijders, Ingrid; Rikers, Remy M. J. P.; Wijnia, Lisette; Loyens, Sofie M. M.

2018-01-01

This study investigated the overall "quality" of the interpersonal relationship students have with faculty and staff, that is, relationship quality (RQ). In relationship management research, RQ is paramount for the creation of bonds with customers, which in turn is necessary for the sustainability of organizations, that is, continuity…

Micro sociological study of family relationships: heuristic potential theoretical principles

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O. P. Zolotnyik

2015-03-01

Full Text Available This article is devoted to demonstrate the heuristic potential of theoretical principles by microsoсiological analysis of one of the indicators of family – family relations. Theoretical analysis of the interaction experience is quite large, but there is the question about it’s possibility to describe the specifics of that relationship that arise in family interaction. The study of family relationships requires an integrated approach to the comprehension of many related components: system of spouses value orientations, family life cycle, socio­economic living conditions of couple. However, the accentuation exactly on action­behavioral aspect allows to make assumptions about correlations between: success of family interaction and microclimate in the family; satisfaction level of interpersonal interaction and overall satisfaction with marriage, familiarity of family interaction and density of childbearing, and so on. The presentation of microsoсiological theoretical achievements will be carried out of sociological schools, orientations and their members that are the most popular references in this area. this paper will presents the theory of exchange, supporters of symbolic interactionism, dramatic and etnometodological approach and family systems theory.

The role of mastery in the relationship between perceived ethnic discrimination and depression: The HELIUS study.

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Slotman, Anne; Snijder, Marieke B; Ikram, Umar Z; Schene, Aart H; Stevens, Gonneke W J M

2017-04-01

This study examined the mediating and moderating role of one's sense of mastery in the relationship between perceived ethnic discrimination and depression. Questionnaire data from participants of the Healthy Life in an Urban Setting (HELIUS) study were used, containing responses from 9,141 Surinamese, Turkish, Moroccan, and Ghanaian immigrant adults, aged 18 to 70, living in Amsterdam, the Netherlands. Results of path modeling indicated that perceptions of ethnic discrimination were positively related to depression symptomatology, and this relationship was moderated and partially mediated by mastery. Results remained fairly robust across sex, educational level, immigrant generation, and ethnicity. This study indicated that mastery may both serve a moderating and mediating role in the relationship between perceived ethnic discrimination and depression, suggestive of a process in which the impact of perceiving discrimination becomes increasingly more deteriorating over time. Thus, interventions focused on mastery may potentially be beneficial to improve ethnic minority mental health. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

The relationship between the Psychopathy Checklist-Revised and the MMPI-2: a pilot study.

Science.gov (United States)

Hansen, Anita L; Stokkeland, Lisa; Johnsen, Bjørn Helge; Pallesen, Ståle; Waage, Leif

2013-04-01

The goal of the study was to investigate the relationship between Hare's four-facet model of psychopathy and the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) in a forensic, culturally homogenous sample. 22 male prisoners from Bergen Prison participated. There was only a statistically significant negative zero-order correlation between the total PCL-R score and the score on the Depression scale of the MMPI-2. However, the results revealed that the four facets had different underlying correlates with negative affectivity. Overall, Facets 1 and 2 showed a tendency toward a negative relationship with the clinical scales on the MMPI-2, while Facets 3 and 4 had a positive relationship. Interestingly, partial correlations showed that Facet 4 of PCL-R was the only facet that correlated statistically significantly with the scores on the Psychopathic Deviate scale of the MMPI-2.

A study on the relationship between operational cash flow and the return of stockholders

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Hassan Ghodrati

2014-07-01

Full Text Available Performance measurement in managerial accounting is normally associated with cash flow and it is executed based on different figures such as testing information content abuse and accounting figures. However, increasing the information content in accrual components of earning and internal performance measurement provides additional informative insights. This paper studies the relationship between operating cash flows and earnings along with total shareholder returns. The study chooses the information of 54 firms from Tehran Stock Exchange. The results show that there were some meaningful relationship between the operating cash flow, profitability and the returns of all stakeholders. However, this happens by increasing profitability and cash flow of information asymmetry proportion to their correlation with the economic efficiency of shareholders’ returns.

An explorative study of the relationship between lifestyle and driving behaviour among young drivers

DEFF Research Database (Denmark)

Møller, Mette

2004-01-01

The high accident risk among young drivers is a well-known and well-documented fact in most countries, including Denmark. Lifestyle has proven to be related to driving behaviour as well as accident risk among young drivers. However, the underlying process through which the relationship between...... the lifestyle and the driving behaviour is established is not yet fully understood. Using focus group interviews divided by sex and education this study explores the psychosocial function of driving as well as the process through which a relationship between lifestyle and driving behaviour is established....... Twenty-nine young drivers living in the Copenhagen area participated in the study. Data were analysed using a modified version of the Editing Analysis Style. (C) 2004 Elsevier Ltd. All rights reserved....

Pengaruh Relationship Marketing Terhadap Kepuasan Dan Loyalitas Nasabah (Studi Pada Nasabah Bank Jatim Cabang Pasuruan)

OpenAIRE

Putri, Ustantia Pratiwi

2014-01-01

This research aims to examine the influence of Relationship Marketing on customer satisfaction and customer loyalty as well as the effect of customer satisfaction on customer loyalty. Therefore the variables used are Mutual benefit, Commitment, Communication and Authencity. The type of the research is explanatory research with quantitative approach. This results of this study indicate that the effect of Relationship Marketing to Customer Loyalty is 25.3% and the inderect effect of Relationshi...

Relationship between Levels of Problematic Internet Usage and Motivation to Study in University Students

Science.gov (United States)

Reed, Phil; Reay, Emma

2015-01-01

This study explored the relationship between problematic levels of Internet use and motivation to study in a university sample. One hundred and sixty-two participants were recruited online and completed four questionnaires: Internet Addiction Test, Hospital Anxiety and Depression Scale, Emotional-Social Loneliness Scale, and the Motivated…

A Relationship Study of Student Satisfaction with Learning Online and Cognitive Load: Initial Results

Science.gov (United States)

Bradford, George R.

2011-01-01

This study sought to explore if a relationship exists between cognitive load and student satisfaction with learning online. The study separates academic performance (a.k.a., "learning") from cognitive load and satisfaction to better distinguish influences on cognition (from cognitive load) and motivation (from satisfaction). Considerations that…

What is the relationship between diversity and performance? A study about the relationship between the proportion of people with disabilities in the productivity of Brazilian firms

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Luciana Carvalho de Mesquita Ferreira

2016-06-01

Full Text Available Purpose – This study aims to analyze the relationship between greater participation of people with disabilities in Brazilian firms and productivity as a performance indicator. Design/methodology/approach – To test the relationship between the proportion of PwD and the productivity of Brazilian firms, we used regression analysis with panel data and a dataset of public information from 46 firms for years 2010 and 2011. Findings – There was no statistical evidence stating that a greater proportion of people with disabilities in the workforce has a negative (or positive relationship with the productivity of Brazilian firms. Conversely, a positive relationship between a greater proportion of people with disabilities and productivity was found amongst firms that present greater social commitment. Originality/value – These results indicate the contingent character associated with diversity management, and that the adoption of social practices by Brazilian firms can be an important mechanism for the management of diversity and inclusion.

Exercise dependence as a mediator of the exercise and eating disorders relationship: a pilot study.

Science.gov (United States)

Cook, Brian; Hausenblas, Heather; Crosby, Ross D; Cao, Li; Wonderlich, Stephen A

2015-01-01

Excessive exercise is a common feature of eating disorders (ED) and is associated with earlier ED onset, more ED symptoms, and higher persistence of ED behavior. Research indicates that exercise amount alone is not associated with ED. The purpose of this study was to investigate pathological attitudes and behaviors related to exercise (e.g., exercise dependence) as a mediator of the exercise and ED relationship. Participants were 43 women with an ED who completed measures of ED symptoms, exercise behavior, and exercise dependence. Analyses were conducted using the indirect bootstrapping method for examining mediation. Exercise dependence mediated the relationship between exercise and ED. This mediation model accounted for 14.34% of the variance in the relationship. Our results extend the literature by offering preliminary evidence of a psychological variable that may be a candidate for future interventions on the exercise and ED relationship. Implications and suggestions for future research are discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.

RELATIONSHIP BETWEEN PLACE ATTACHMENT AND EVENT SATISFACTION: A STUDY ON UNIVERSITY STUDENTS

OpenAIRE

ARGAN, Metin; KAYA, Sabri; TOKAY ARGAN, Mehpare; AKYILDIZ, Müge; KORKMAZ, Tanju

2015-01-01

The aim of the study is to reveal the dimensions of place attachment and to analyze the relationship between event satisfaction and place attachment dimensions. The study involved a quantitative research methodology employing a questionnaire and convenience sampling with a total sample of 300 Anadolu University’s students within Eskişehir of the middle region in Turkey. The first part of the questionnaire contained 16 statements related to place attachment. Second part was related to the scal...

Relationship between Screen-Time and Motor Proficiency in Children: A Longitudinal Study

Science.gov (United States)

Cadoret, Geneviève; Bigras, Nathalie; Lemay, Lise; Lehrer, Joanne; Lemire, Julie

2018-01-01

The objective of this longitudinal study was to examine the relationship between screen time (ST) and children's motor proficiency. The amount of time 113 children spent watching television, using a computer, and playing video games as reported by parents at ages 4, 5, and 7 was measured and children's motor skills were evaluated at age 7 with the…

RELATIONSHIP MARKETING DAN LOYALLITAS NASABAH: STUDI PADA NASABAH BRI SYARIAH MALANG

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Nur Asnawi

2017-03-01

Full Text Available One of strategies used by BRI Syariah Malang in emulation of banking world wasfocusing itself in constructing relationship with customers by applying relationship market-ing. It was hoped to get the customers in the final purpose. Relationship marketing could bedeveloped into three steps, financial benefits, social benefits, and structural benefits. Thisresearch was to know the influence of relationship marketing which consisted of financialbenefits, social benefits, and structural benefits towards customer loyalty in BRI Syariah ofMalang. The total sample was 100 respondents. The analysis system used was the doubleregression model. The result of the double linear regression analysis was that the writerfound out that financial benefit, social benefits and structural benefits influenced customerloyalty at BRI Syariah of Malang simultaneously. Besides, the most influencing variable wassocial benefits.

Detecting biodiversity hotspots by species-area relationships: a case study of Mediterranean beetles.

Science.gov (United States)

Fattorini, Simone

2006-08-01

Any method of identifying hotspots should take into account the effect of area on species richness. I examined the importance of the species-area relationship in determining tenebrionid (Coleoptera: Tenebrionidae) hotspots on the Aegean Islands (Greece). Thirty-two islands and 170 taxa (species and subspecies) were included in this study. I tested several species-area relationship models with linear and nonlinear regressions, including power exponential, negative exponential, logistic, Gompertz, Weibull, Lomolino, and He-Legendre functions. Islands with positive residuals were identified as hotspots. I also analyzed the values of the C parameter of the power function and the simple species-area ratios. Species richness was significantly correlated with island area for all models. The power function model was the most convenient one. Most functions, however identified certain islands as hotspots. The importance of endemics in insular biotas should be evaluated carefully because they are of high conservation concern. The simple use of the species-area relationship can be problematic when areas with no endemics are included. Therefore the importance of endemics should be evaluated according to different methods, such as percentages, to take into account different levels of endemism and different kinds of "endemics" (e.g., endemic to single islands vs. endemic to the archipelago). Because the species-area relationship is a key pattern in ecology, my findings can be applied at broader scales.

No Relationship Between Hamstring Flexibility and Hamstring Injuries in Male Amateur Soccer Players: A Prospective Study.

Science.gov (United States)

van Doormaal, Mitchell C M; van der Horst, Nick; Backx, Frank J G; Smits, Dirk-Wouter; Huisstede, Bionka M A

2017-01-01

In soccer, although hamstring flexibility is thought to play a major role in preventing hamstring injuries, the relationship between hamstring flexibility and hamstring injuries remains unclear. To investigate the relationship between hamstring flexibility and hamstring injuries in male amateur soccer players. Case-control study; Level of evidence, 3. This study included 450 male first-class amateur soccer players (mean age, 24.5 years). Hamstring flexibility was measured by performing the sit-and-reach test (SRT). The relationship between hamstring flexibility and the occurrence of hamstring injuries in the following year, while adjusting for the possible confounding effects of age and previous hamstring injuries, was determined with a multivariate logistic regression analysis. Of the 450 soccer players, 21.8% reported a hamstring injury in the previous year. The mean (±SD) baseline score for the SRT was 21.2 ± 9.2 cm. During the 1-year follow-up period, 23 participants (5.1%) suffered a hamstring injury. In the multivariate analysis, while adjusting for age and previous injuries, no significant relationship was found between hamstring flexibility and hamstring injuries ( P = .493). In this group of soccer players, hamstring flexibility (measured with the SRT) was not related to hamstring injuries. Age and previous hamstring injuries as possible confounders did not appear to influence this relationship. Other etiological factors need to be examined to further elucidate the mechanism of hamstring injuries.

Environmental influence of problematic social relationships on adolescents' daily cortisol secretion: a monozygotic twin-difference study.

Science.gov (United States)

Brendgen, M; Ouellet-Morin, I; Lupien, S J; Vitaro, F; Dionne, G; Boivin, M

2017-02-01

This study investigated the potential environmental effects of peer victimization and the quality of relationships with parents and friends on diurnal cortisol secretion in mid-adolescence. This study used the monozygotic (MZ) twin-difference design to control for genetic effects and thus estimate the unique environmental influences on diurnal cortisol. Participants were 136 MZ twin pairs (74 female pairs) for whom cortisol was assessed four times per day over four collection days grouped in a 2-week period in grade 8 (mean age = 14.07 years). Participants also provided self-reports of peer victimization from grade 4 to grade 8 and of the relationship quality with the mother, father and best friend in grade 8. The expected pattern of diurnal cortisol secretion was observed, with high levels at awakening followed by an increase 30 min later and a progressive decrease subsequently. Controlling for a host of confounders, only within-twin pair differences in peer victimization and a problematic relationship with the mother were significantly linked to twin differences in diurnal cortisol secretion. Specifically, whereas a more problematic mother-child relationship was associated with morning cortisol secretion, peer victimization was linked to cortisol secretion later in the day (diurnal slope). Controlling for genetic influences and other confounders, stressful relationships with peers and the mother exert unique and time-specific environmental influences on the pattern of diurnal cortisol secretion in mid-adolescence.

Study of solar radiation prediction and modeling of relationships between solar radiation and meteorological variables

International Nuclear Information System (INIS)

Sun, Huaiwei; Zhao, Na; Zeng, Xiaofan; Yan, Dong

2015-01-01

Highlights: • We investigate relationships between solar radiation and meteorological variables. • A strong relationship exists between solar radiation and sunshine duration. • Daily global radiation can be estimated accurately with ARMAX–GARCH models. • MGARCH model was applied to investigate time-varying relationships. - Abstract: The traditional approaches that employ the correlations between solar radiation and other measured meteorological variables are commonly utilized in studies. It is important to investigate the time-varying relationships between meteorological variables and solar radiation to determine which variables have the strongest correlations with solar radiation. In this study, the nonlinear autoregressive moving average with exogenous variable–generalized autoregressive conditional heteroscedasticity (ARMAX–GARCH) and multivariate GARCH (MGARCH) time-series approaches were applied to investigate the associations between solar radiation and several meteorological variables. For these investigations, the long-term daily global solar radiation series measured at three stations from January 1, 2004 until December 31, 2007 were used in this study. Stronger relationships were observed to exist between global solar radiation and sunshine duration than between solar radiation and temperature difference. The results show that 82–88% of the temporal variations of the global solar radiation were captured by the sunshine-duration-based ARMAX–GARCH models and 55–68% of daily variations were captured by the temperature-difference-based ARMAX–GARCH models. The advantages of the ARMAX–GARCH models were also confirmed by comparison of Auto-Regressive and Moving Average (ARMA) and neutral network (ANN) models in the estimation of daily global solar radiation. The strong heteroscedastic persistency of the global solar radiation series was revealed by the AutoRegressive Conditional Heteroscedasticity (ARCH) and Generalized Auto

Project STARS (Studies on Trajectories of Adolescent Relationships and Sexuality) : A longitudinal, multi-domain study on sexual development of Dutch adolescents

NARCIS (Netherlands)

Reitz, Ellen; van de Bongardt, Daphne; Baams, Laura; Doornwaard, Suzan; Dalenberg, Wieke; Dubas, Judith; van Aken, Marcel; Overbeek, Geertjan; ter Bogt, Tom; van den Eijnden, Regina; Vanwesenbeeck, Wilhelmina; Kunnen, Saskia; Timmerman, Greetje; van Geert, Paul; Deković, Maja

2015-01-01

This study gives an overview of Project STARS (Studies on Trajectories of Adolescent Relationships and Sexuality), a four-wave longitudinal study of 1297 Dutch adolescents. First, the sample, measures and four sub-projects are described. Second, hierarchical regression analyses were conducted to

Project STARS (Studies on Trajectories of Adolescent Relationships and Sexuality): A longitudinal, multi-domain study on sexual development of Dutch adolescents

NARCIS (Netherlands)

Reitz, E.; van de Bongardt, D.; Baams, L.; Doornwaard, S.; Dalenberg, W.; Dubas, J.; van Aken, M.; Overbeek, G.; ter Bogt, T.; van der Eijnden, R.; Vanwesenbeeck, I.; Kunnen, S.; Timmerman, G.; van Geert, P.; Deković, M.

2015-01-01

This study gives an overview of Project STARS (Studies on Trajectories of Adolescent Relationships and Sexuality), a four-wave longitudinal study of 1297 Dutch adolescents. First, the sample, measures and four sub-projects are described. Second, hierarchical regression analyses were conducted to

Observational study to characterise 24-hour COPD symptoms and their relationship with patient-reported outcomes : results from the ASSESS study

NARCIS (Netherlands)

Miravitlles, Marc; Worth, Heinrich; Soler Cataluna, Juan Jose; Price, David; De Benedetto, Fernando; Roche, Nicolas; Godtfredsen, Nina Skavlan; van der Molen, Thys; Lofdahl, Claes-Goran; Padulles, Laura; Ribera, Anna

2014-01-01

Background: Few studies have investigated the 24-hour symptom profile in patients with COPD or how symptoms during the 24-hour day are inter-related. This observational study assessed the prevalence, severity and relationship between night-time, early morning and daytime COPD symptoms and explored

Gender role attitudes, relationship efficacy, and self-disclosure in intimate relationships.

Science.gov (United States)

Horne, Rebecca M; Johnson, Matthew D

2018-01-01

Drawing from the intimacy process model and data from 5,042 individuals who remained partnered across Waves 1 and 2 of the German Panel Analysis of Intimate Relationships and Family Dynamics (pairfam), this study examined the contributions of traditional gender role attitudes and relationship efficacy in predicting levels of self-disclosure within an intimate relationship. Independent samples t-tests demonstrated females scored higher than males on self-disclosure and relationship efficacy measures but lower on traditional gender role attitudes. An ordinary least squares regression analysis revealed relationship efficacy was a stronger predictor of self-disclosure compared to traditional gender role attitudes, which were not associated with self-disclosure. The findings suggest attitudes with an interpersonal motivational system may be especially important for setting the intimacy process into motion within an intimate union.

“Expectant Parents”: Study protocol of a longitudinal study concerning prenatal (risk factors and postnatal infant development, parenting, and parent-infant relationships

Directory of Open Access Journals (Sweden)

Maas A Janneke BM

2012-06-01

Full Text Available Abstract Background While the importance of the infant-parent relationship from the child’s perspective is acknowledged worldwide, there is still a lack of knowledge about predictors and long-term benefits or consequences of the quality of parent-infant relationships from the parent’s perspective. The purpose of this prospective study is to investigate the quality of parent-infant relationships from parents’ perspectives, both in the prenatal and postpartum period. This study therefore focuses on prenatal (risk factors that may influence the quality of pre- and postnatal bonding, the transition to parenthood, and bonding as a process within families with young children. In contrast to most research concerning pregnancy and infant development, not only the roles and experiences of mothers during pregnancy and the first two years of infants’ lives are studied, but also those of fathers. Methods/design The present study is a prospective longitudinal cohort study, in which pregnant women (N = 466 and their partners (N = 319 are followed from 15 weeks gestation until their child is 24 months old. During pregnancy, midwives register the presence of prenatal risk factors and provide obstetric information after the child’s birth. Parental characteristics are investigated using self-report questionnaires at 15, 26, and 36 weeks gestational age and at 4, 6, 12, and 24 months postpartum. At 26 weeks of pregnancy and at 6 months postpartum, parents are interviewed concerning their representations of the (unborn child. At 6 months postpartum, the mother-child interaction is observed in several situations within the home setting. When children are 4, 6, 12, and 24 months old, parents also completed questionnaires concerning the child’s (social-emotional development and the parent-child relationship. Additionally, at 12 months information about the child’s physical development and well-being during the first year of life is retrieved from

A Study on the Relationship between Human Resource Management Practices and Organizational Performance

Directory of Open Access Journals (Sweden)

Özden AKIN

2012-12-01

Full Text Available The main goal of this study is to investigate the relationship between organizational performance variables and Human Resource Management practices. Workforce planning, training and development, performance appraisal, rewarding, firm-employee relationship, and internal communication are used as human resource management practices. Employee turnover rate, employee productivity, and sales are used as organizational performance variables. The results are collected by survey from 108 companies which are the members of Istanbul Chamber of Industry (ICI. Analyses show that workforce planning has a significant effect on employee productivity and sales, but no significant effect on employee turnover rate. The results also show that employee turnover rate is negatively associated with employee productivity and sales.

Patient relationship management: an overview and study of a follow-up system.

Science.gov (United States)

Oinas-Kukkonen, Harri; Räisänen, Teppo; Hummastenniemi, Niko

2008-01-01

Customer relationship management research is utilized to explain the need for a more patient-oriented support in patient care. This article presents a European study on how various hospital units of a single healthcare organization have utilized a patient relationship management system--in particular a patient treatment follow-up system--and how it affects patient care and the knowledge work performed by the medical staff. Eight physicians were interviewed at a university hospital on whether patient treatment was improved through a follow-up system that had been in use in the case organization for three years. The interviewees represented various hospital units, and all of them had used the system at their own unit. The results indicate that it is possible to improve patient care through more personalized treatment. The follow-up treatment system seems to be a tool to create and maintain better communication with the patients rather than just a technological solution. It may help better understand and analyze both individual patients and patient groups. For individual physicians it provides a way to reflect professional skills. The system was lacking in its support for one-to-one communication with patients. Nevertheless, the system is an example of patient relationship management which may help healthcare units to move towards a more patient-oriented care.

Humor in leader-follower relationships : Humor styles, similarity and relationship quality.

NARCIS (Netherlands)

Wisse, Barbara; Rietzschel, Eric

2014-01-01

The present study focuses on how humor may affect the quality of the relationship between leader and follower (LMX). More specifically, we examined the impact of follower self-reported humor style and leader self-reported humor style on the extent to which followers perceived their relationship with

Caring for adolescent students: a grounded theory study of teachers' perspectives on their relationships with students in secondary schools.

OpenAIRE

Cullingworth, Erin

2014-01-01

This grounded theory study explored secondary teachers’ perspectives on their relationships with their adolescent students: the kinds of relationships they want to create, why they believe such relationships are important, and what obstacles they perceive to their construction. Teachers who felt they were able to create positive, effective relationships with their students tended to work in mini-school programs, to practice a kind of “authoritative” teaching similar to Baumrind’s (1978; 1991...

A Study of the Interrelationships among Service Recovery, Relationship Quality, and Brand Image in Higher Education Industries

Science.gov (United States)

Chen, Yu-Chuan

2015-01-01

This study aims to investigate the direction and strength of the relationships among service recovery, relationship quality, and brand image in higher education industries. This research provides a framework for school managers to understand service recovery from an operations perspective. Structural equation models were used to test the proposed…

Observational study of the relationship between entrainment rate and relative dispersion in deep convective clouds

Science.gov (United States)

Guo, Xiaohao; Lu, Chunsong; Zhao, Tianliang; Liu, Yangang; Zhang, Guang Jun; Luo, Shi

2018-01-01

This study investigates the influence of entrainment rate (λ) on relative dispersion (ε) of cloud droplet size distributions (CDSD) in the 99 growing precipitating deep convective clouds during TOGA-COARE. The results show that entrainment suppresses ε, which is opposite to the traditional understanding that entrainment-mixing broadens CDSD. To examine how the relationship between ε and λ is affected by droplets with different sizes, CDSDs are divided into three portions with droplet radius processes is developed to illustrate the possible scenarios entailing different relationships between ε and λ. The number concentration of small droplets and the degree of evaporation of small droplets are found to be key factors that shift the sign (i.e., positive or negative) of the ε-λ relationship.

The relationship between sleep and wake habits and academic performance in medical students: a cross-sectional study

OpenAIRE

BaHammam Ahmed S; Alaseem Abdulrahman M; Alzakri Abdulmajeed A; Almeneessier Aljohara S; Sharif Munir M

2012-01-01

Abstract Background The relationship between the sleep/wake habits and the academic performance of medical students is insufficiently addressed in the literature. This study aimed to assess the relationship between sleep habits and sleep duration with academic performance in medical students. Methods This study was conducted between December 2009 and January 2010 at the College of Medicine, King Saud University, and included a systematic random sample of healthy medical students in the first ...

A Sectional Study: The Relationship between Perceived Social Support and Depression in Turkish Infertile Women

Directory of Open Access Journals (Sweden)

Kubra Erdem

2014-11-01

Full Text Available Background: Studies conducted on infertile women in the literature investigated some features such as depression, anxiety, loneliness, and social support. However, there has been no study examining the relationship between levels of perceived social support and depression in infertile women. Considering this deficiency, the study was conducted to determine the relationship between perceived social support and depression in infertile women. The purpose of this study is to determine the relationship between perceived social support and depression in infertile women. Materials and Methods: This descriptive and sectional study was conducted between 16 April and 31 October 2012 in in vitro fertilisation (IVF Centre of Fırat University Research Hospital. Sampling formula was used in cases when the number of elements in the population was not known to calculate minimum sample size required to be included in the study. A total of 238 women who applied to the relevant centre between the specified dates constituted the sample group of the study. A Questionnaire Form, Beck Depression Inventory (BDI and the Multidimensional Scale of Perceived Social Support (MSPSS were used to collect the data. A pilot study was carried out on nine infertile women. As a result of the pilot study, we formed the final version of the Questionnaire Form. The data of these nine women were not involved in the research. The data obtained from the study was assessed using Statistical Package for the Social Sciences (SPSS; SPSS Inc., Chicago, IL, USA version 15.0. Percentage distribution, mean, t test, one-way analysis of variance (One-Way ANOVA, and Pearson correlation analysis were used to evaluate the data. Results: The women’s total mean score on the BDI was 12.55 ± 8.07. Scores obtained by women on the MSPSS was 15.75 ± 8.53 for the subscale of friend, 21.52 ± 8.20 for the subscale of family, and 15.62 ± 8.45 for the subscale of significant others. The women’s total

Motivation Mediates the Perfectionism-Burnout Relationship: A Three-Wave Longitudinal Study With Junior Athletes.

Science.gov (United States)

Madigan, Daniel J; Stoeber, Joachim; Passfield, Louis

2016-08-01

Perfectionism in sports has been shown to predict longitudinal changes in athlete burnout. What mediates these changes over time, however, is still unclear. Adopting a self-determination theory perspective and using a three-wave longitudinal design, the current study examined perfectionistic strivings, perfectionistic concerns, autonomous motivation, controlled motivation, and athlete burnout in 141 junior athletes (mean age = 17.3 years) over 6 months of active training. When multilevel structural equation modeling was employed to test a mediational model, a differential pattern of between- and within-person relationships emerged. Whereas autonomous motivation mediated the negative relationship that perfectionistic strivings had with burnout at the between- and within-person level, controlled motivation mediated the positive relationship that perfectionistic concerns had with burnout at the between-persons level only. The present findings suggest that differences in autonomous and controlled motivation explain why perfectionism predicts changes in athlete burnout over time.

Studying the electronic customer relationship management and its ...

African Journals Online (AJOL)

... was returned after distributing of 80 samples. Hypotheses of research have been analyzed using spss software and Spearman correlation test. The results prove all hypotheses of research. Keywords: Electronic Banking, Service Quality, Customer Satisfaction, Management of. Relationship with Customer, Commitment ...

Inter-relationships of haplosporidians deduced from ultrastructural studies

NARCIS (Netherlands)

Hine, P.M.; Carnegie, R.B.; Burreson, E.M.; Engelsma, M.Y.

2009-01-01

We reviewed papers reporting haplosporidian ultrastructure to compare inter-relationships based on ultrastructure with those based on molecular data, to identify features that may be important in haplosporidian taxonomy, and to consider parasite taxonomy in relation to host taxonomy. There were

The relationship of spiritual wellbeing, loneliness, and relationship satisfaction, to life contentment

OpenAIRE

Leeth, Elizabeth M.

1995-01-01

There is an identified need for spirituality to be taught in mental health therapy programs. Spirituality is about the connectedness we feel and the relationships we establish with self, others, and the universe. This study examined the relationship of spiritual well being, loneliness, and relationship satisfaction to life contentment. Each of the eighty-one respondents enrolled at VPI completed the "Spiritual Well being Scale" and "Abbreviated Loneliness Scale" (Paloutzian & E...

Jealousy and Relationship Closeness

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Mark Attridge

2013-02-01

Full Text Available This study confirmed a hypothesis from the Emotion-in-Relationships conceptual model, which predicts that greater interdependence between relationship partners—or closeness—creates the potential for jealousy. The study also sought to better define the positive side of romantic jealousy in addition to its more negative attributes. College students in premarital relationships (N = 229 completed a questionnaire, including 27 different measures and the Multidimensional Jealousy Scale. Select data were obtained from 122 cases at 3-month follow-up. Each jealousy scale was tested for associations with demographic (age, sex, and race, person (life satisfaction, loneliness, romantic attachment styles, love styles, and romantic beliefs, and relationship (affective, closeness, and social exchange theory constructs. Results clearly distinguished emotional/reactive jealousy as mostly “good” and cognitive/suspicious jealousy as “bad.” Behavioral jealousy was associated with few measures. Implications are discussed for the interdependence model of relationships and the transactional model of jealousy.

[Causal relationship between assertiveness and adjustment in children: A short-term longitudinal study].

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Eguchi, Megumi; Hamaguchi, Yoshikazu

2015-08-01

This study examined the causal relationships between assertiveness and both internal and external adjustment in children. Elementary school children in grades four through six (N = 284) participated in the study, which used a short-term longitudinal design. The children completed questionnaires twice during a 6-months period. They responded to assertiveness questionnaires that included two components: "self-expression" and "consideration of others". They also completed a self-esteem scale as an index of internal adjustment, and the Class Life Satisfaction scale as an index of external adjustment. There was a positive causative relationship between "self-expression" and internal adjustment and between "consideration for others" and external adjustment. In addition, the effects on adjustment varied according to the type of assertiveness. Cluster analysis and MANOVA indicated that the group with high "self-expression" and "consideration for others" had high internal and external adjustment, while the children with poor assertiveness showed the lowest degree of adaptivity.

Customer relationship management in the contract pharmaceutical industry: an exploratory study for measuring success.

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Kros, John F; Nadler, Scott; Molis, Justin

2007-01-01

Managing customer relationships is a very important issue in business-to-business markets. This research investigates the growing number of available resources defining Customer Relationship Management (CRM) efforts, and how they are being applied within the Contract Pharmaceutical Manufacturing industry. Exploratory study results using face-to-face and telephone questionnaires based on four criteria for rating a company's CRM efforts are presented. Data was collected from large Contract Pharmaceutical Manufacturing companies in the US market. The results and conclusions are discussed relating how the Contract Pharmaceutical Manufacturing industry is implementing CRM including some potential steps to take when considering a CRM initiative.

Benchmarking Supplier Development: An Empirical Case Study of Validating a Framework to Improve Buyer-Supplier Relationship

OpenAIRE

Shahzad Khuram; Sillanpää Ilkka; Sillanpää Elina; Imeri Shpend

2016-01-01

In today’s dynamic business environment, firms are required to utilize efficiently and effectively all the useful resources to gain competitive advantage. Supplier development has evolved as an important strategic instrument to improve buyer supplier relationships. For that reason, this study focuses on providing the strategic significance of supplier development approaches to improve business relationships. By using qualitative research method, an integrated framework of supplier development...

Governing IT outsourcing relationships

CERN Document Server

Kuhlmann, Daniel

2012-01-01

Hauptbeschreibung The dynamics of the relationship between service recipient and service provider in IS outsourcing relationships recently gained increased attention as relationships are believed to have a considerable influence on IS outsourcing success. This study adds to this growing field of interest by developing an IS outsourcing relationship framework in the form of a process model. Three rather disjointed areas of research, namely contractual governance, relational norms, and control, have been set in a common context by interrelating them as the three main governance modes

An empirical study on human resource competencies and its relationship with productivity

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Hasan Darvish

2012-10-01

Full Text Available This study evaluates the impact of human resource competencies on productivity. The proposed study considers different issues such as different competencies associated with human resources, how we can persuade and strengthen such competencies in organizations and whether human resource competencies impact organizational productivity or not. There are one main hypothesis six minor hypotheses in this study. The proposed study uses descriptive and regression technique to perform the study. The population of this study includes all managers who work for an Iranian petroleum company. This result of this survey shows that that human resource competencies impact organizational productivity. In addition, all dimensions of human resource competencies had significant relationship on organizational productivity.

Relationship status and relationship instability, but not dominance, predict individual differences in baseline cortisol levels.

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Dario Maestripieri

Full Text Available We investigated variation in baseline cortisol levels in relation to relationship status (single or in a relationship, relationship characteristics (length, stability, presence or absence of clear dominance, or individual attributes (dominant or subordinate status, relative physical attractiveness, relationship worries. Study participants were 77 men and 75 women aged between 18 and 38 years. Individuals in romantic relationships had lower cortisol levels than singles. Individuals of African ethnicity, however, showed the opposite pattern. Individuals who perceived their relationship to be highly unstable had higher cortisol levels. Aside from African-Americans, married individuals reported the lowest relationship instability and the lowest cortisol levels, followed by individuals in long-term relationships, and by individuals in short-term relationships. The presence or absence of clear dominance in the relationship, dominance status, or relationship worries did not affect cortisol levels. Therefore relationship status and relationship instability were better predictors of variation in cortisol (presumably through stress-related mechanisms than individual attributes.

Relationship status and relationship instability, but not dominance, predict individual differences in baseline cortisol levels.

Science.gov (United States)

Maestripieri, Dario; Klimczuk, Amanda C E; Seneczko, Marianne; Traficonte, Daniel M; Wilson, M Claire

2013-01-01

We investigated variation in baseline cortisol levels in relation to relationship status (single or in a relationship), relationship characteristics (length, stability, presence or absence of clear dominance), or individual attributes (dominant or subordinate status, relative physical attractiveness, relationship worries). Study participants were 77 men and 75 women aged between 18 and 38 years. Individuals in romantic relationships had lower cortisol levels than singles. Individuals of African ethnicity, however, showed the opposite pattern. Individuals who perceived their relationship to be highly unstable had higher cortisol levels. Aside from African-Americans, married individuals reported the lowest relationship instability and the lowest cortisol levels, followed by individuals in long-term relationships, and by individuals in short-term relationships. The presence or absence of clear dominance in the relationship, dominance status, or relationship worries did not affect cortisol levels. Therefore relationship status and relationship instability were better predictors of variation in cortisol (presumably through stress-related mechanisms) than individual attributes.

Second vowel formant relationship to adduction: A preliminary study

Science.gov (United States)

Hanrahan, Kevin G.

The relationship between the vocal tract and the larynx in the formation of vowels has been debated for decades. Vowels were first thought to have been formed in the larynx; then later it was believed that they were formed solely in the vocal tract. In the 1960s Fant formalized this belief into the Source-Filter Theory of Vowel Formation. The theory was interpreted by voice teachers to mean that the larynx had very little to do with the formation of vowels, and this interpretation has dominated voice teaching for decades. Recent research, however, is now suggesting that the larynx and the vocal tract are interactive with each other, meaning that a change of muscular function in the larynx will create a change of resonator function in the vocal tract, and vice versa. This conclusion is drawn mainly on the work of Titze, Story, Laukkanen, et.al. They have found that a relationship exists between laryngeal function and the first vowel formant (F1). When examining research on the second vowel formant (F2), this author discovered that there may be a relationship between F2 and adduction. Therefore, based on present evidence, it was hypothesized that an elevated frequency of F2 corresponded to an increase in adduction. The hypothesis was examined by comparing the resonance output and glottal closure between vowels where F2 was elevated and vowels without modification of F2. Subjects were asked to sing [i], [a], and [u] at a medium dynamic level on D4, G#4, and D5 for the female subjects and an octave below for the male subjects, once using a "generic" version of the vowel, meaning what they considered a "nice, easy, and generic" version of the vowel to be, and then again modifying the vowel to increase the frequency of the upper harmonics. Electroglottogram, pitch, intensity, and formant data were collected and compared. An increase in the frequency of F2 corresponded to an increase in the Closed Quotient (CQ), the length of time the vocal folds are closed, in a few

IMPACTS OF OWN BRANDS STRATEGY ON MANUFACTURER – RETAILER RELATIONSHIP: CASE STUDIES IN LARGE SIZE COMPANIES

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Renato Telles

2012-05-01

Full Text Available The study of marketing and production strategy of own brand products requires an understanding of both the benefits gained by retailers and manufacturers involved in this activity and also the effects of this strategy on the relationship between these companies. According to this idea, a qualitative and descriptive work was conducted, based on six case studies, three of them on large product manufacturers and three on large retailers. The aim of this study is defined is threefold: (1 to analyze the expectations of manufacturers and retailers with their own brands’ current operations, (2 to analyze the expectations of manufacturers and retailers with their own brands’ future operations, and (3 to analyze the influence of the own brands adoption on the relationship between manufacturers and retailers. The results indicate that (a current operations are primarily based on economic reasons (market share, and use of spare capacity, (b future operations are perceived from a marketing perspective (survival, and (c the adoption of own brand strategy does not harm the relationship between the parties – both manufacturers and retailers –, unlike the earlier studies indicated.