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Sample records for regulations doe orders

  1. NRC regulation of DOE facilities

    International Nuclear Information System (INIS)

    Buhl, A.R.; Edgar, G.; Silverman, D.; Murley, T.

    1997-01-01

    The US Department of Energy (DOE), its contractors, and the Nuclear Regulatory Commission (NRC) are in for major changes if the DOE follows through on its intentions announced December 20, 1996. The DOE is seeking legislation to establish the NRC as the regulatory agency with jurisdiction over nuclear health, safety, and security at a wide range of DOE facilities. At this stage, it appears that as many as 200 (though not all) DOE facilities would be affected. On March 28, 1997, the NRC officially endorsed taking over the responsibility for regulatory oversight of DOE nuclear facilities as the DOE had proposed, contingent upon adequate funding, staffing resources, and a clear delineation of NRC authority. This article first contrasts the ways in which the NRC and the DOE carry out their basic regulatory functions. Next, it describes the NRC's current authority over DOE facilities and the status of the DOE's initiative to expand that authority. Then, it discusses the basic changes and impacts that can be expected in the regulation of DOE facilities. The article next describes key lessons learned from the recent transition of the GDPs from DOE oversight to NRC regulation and the major regulatory issues that arose in that transition. Finally, some general strategies are suggested for resolving issues likely to arise as the NRC assumes regulatory authority over DOE facilities

  2. The DNR Order: What Does it Mean?

    Directory of Open Access Journals (Sweden)

    John Y.C. Tsang Md

    2010-04-01

    Full Text Available As medical science continues to advance, patients nowadays with progressive cardiopulmonary diseases live to older ages. However, they too will eventually reach their unsustainable physiological limit and many die in poor health and discomfort prior to their demise. Regrettably many physicians have not kept pace in dealing with the inevitable end-of- life issues, along with modern technological developments. Without proper guidance, ill-informed patients often face unnecessary anxiety, receive futile resuscitation at the expense of their dignity and public cost which has and will become increasingly overwhelming according to our current demographic trends. In any health care reform, experts often suggest that difficult questions will have to be asked but the solutions are at least partly in the logistical details. From time to time, we see an isolated “Do Not Resuscitate” or DNR order in the chart, which is not always followed by thoughtful discussion on the boundary of care, either simultaneously or known to be followed up soon. This paper attempts to begin asking some of these difficult questions, point out the fallacies of this order and expose the weaknesses in the present state of entitlement by public demand if physicians retreats more from the discussion. The solution does not lie in asking the questions but in changing the practice pattern in real life on a continuous basis, hopefully to be eventually accepted by most, if not all.

  3. Review of orders and regulations requiring environmental protection

    International Nuclear Information System (INIS)

    Kelly, E.; Cunningham, R.; Michael, D.

    1996-01-01

    With the increased awareness of and interest in potential ecological risks associated with past, current, and future Department of Energy (DOE) activities, DOE's Defense Programs (DP) Office of Technical and Environmental Support sponsored a study to (1) evaluate the effectiveness of the current compliance-driven environmental protection and assessment efforts relative to ecological concerns; (2) explore the need for a more focused, integrated approach to address ecological impacts; and (3) identify the requirements for an integrated approach. The study explored four questions. (a) Which federal regulations and DOE orders either explicitly require ecological assessments or implicitly require them through environmental protection language? (b) What currently is being done at selected DOE facilities to implement these regulations and orders? (c) What are private sector industries doing in terms of ecological risk assessments and how do industry approaches and issues compare with those of DOE? (d) What, if anything, in addition to current efforts is needed to ensure the protection of ecological resources associated with DOE facilities, to support defensible decision making, and to improve efficiency? The results of this study are presented in a report titled open-quotes Integrated, Comprehensive Ecological Impact Assessments In Support of Department of Energy Decision Makingclose quotes. This report is a companion document to that report. This report provides a more detailed discussion of the document reviews of the relevant environmental protection regulations and current and pending DOE orders. The main goal of the document reviews was to understand existing requirements for ecological data collection and impact assessments

  4. 300 Area TEDF DOE order compliance applicability assessment

    Energy Technology Data Exchange (ETDEWEB)

    Eacker, J.A.

    1994-11-08

    This report summarizes the results of an effort to determine applicability of Department of Energy Orders at the Hanford 300 Area Treated Effluent Disposal Facility (TEDF). This assessment placed each of the reviewed orders into one of three compliance categories: (A) order applicable at a facility specific level (20 identified); (B) order applicable at a policy level (11 identified); or (C) order not applicable (21 identified). The scope of the assessment from the DOE Order standpoint was the 52 Level 1 Orders of interest to the Defense Nuclear Facility Safety Board (DNFSB). Although the TEDF is a non-nuclear facility, this order basis was chosen as a Best Management Practice to be consistent with ongoing efforts across the Hanford Site. Three tables in the report summarize the DOE order applicability by the compliance categories, with a table for Level A, Level B, and Level C applicability. The attachment to the report documents the compliance applicability assessment for each individual DOE Order.

  5. 300 Area TEDF DOE order compliance applicability assessment

    International Nuclear Information System (INIS)

    Eacker, J.A.

    1994-01-01

    This report summarizes the results of an effort to determine applicability of Department of Energy Orders at the Hanford 300 Area Treated Effluent Disposal Facility (TEDF). This assessment placed each of the reviewed orders into one of three compliance categories: (A) order applicable at a facility specific level (20 identified); (B) order applicable at a policy level (11 identified); or (C) order not applicable (21 identified). The scope of the assessment from the DOE Order standpoint was the 52 Level 1 Orders of interest to the Defense Nuclear Facility Safety Board (DNFSB). Although the TEDF is a non-nuclear facility, this order basis was chosen as a Best Management Practice to be consistent with ongoing efforts across the Hanford Site. Three tables in the report summarize the DOE order applicability by the compliance categories, with a table for Level A, Level B, and Level C applicability. The attachment to the report documents the compliance applicability assessment for each individual DOE Order

  6. The changing Arena: New DOE waste management orders

    International Nuclear Information System (INIS)

    Albenesius, E.L.; Kluk, A.F.

    1988-01-01

    There are five orders that address waste management within the Department of Energy (DOE); three of these orders are being revised, which emphasize the rapidly changing arena in which the department is contending in this field. The need to change the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) Order arose from the Superfund amendments of 1986 (SARA) with its hammer provisions in Section 120 for compliance at Federal facilities. The need to change the Hazardous and Mixed Waste Management Order was accelerated by the promulgation by DOE of the new mixed waste rule on May 1, 1987, (1) and cancellation of the obsolete existing order on October 5, 1987. The new rule requires coregulation of all DOE mixed waste with the Environmental Protection Agency (EPA) and the respective authorized states. 5 refs

  7. Revision of DOE Order 5820.2 Radioactive Waste Management

    International Nuclear Information System (INIS)

    Albenesius, E.L.

    1988-01-01

    The Radioactive Waste Management Order of Department of Energy (DOE), 5820.2 was radically revised to a more prescriptive style with accountable performance objectives. In particular, major changes were required in the low-level radioactive waste (LLW) Management Chapter. These changes will move the Department toward equivalence with Nuclear Regulatory Commission's 10 CFR 61 at arid disposal sites and, because of emphasis on groundwater protection beyond these requirements for DOE disposal sites in humid areas. Formal issue of the Order is expected at the end of September 1988

  8. 21 CFR 1.378 - What criteria does FDA use to order a detention?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false What criteria does FDA use to order a detention? 1.378 Section 1.378 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL GENERAL ENFORCEMENT REGULATIONS Administrative Detention of Food for Human or Animal Consumption...

  9. DOE Order 5480.28 Hanford facilities database

    Energy Technology Data Exchange (ETDEWEB)

    Hayenga, J.L., Westinghouse Hanford

    1996-09-01

    This document describes the development of a database of DOE and/or leased Hanford Site Facilities. The completed database will consist of structure/facility parameters essential to the prioritization of these structures for natural phenomena hazard vulnerability in compliance with DOE Order 5480.28, `Natural Phenomena Hazards Mitigation`. The prioritization process will be based upon the structure/facility vulnerability to natural phenomena hazards. The ACCESS based database, `Hanford Facilities Site Database`, is generated from current Hanford Site information and databases.

  10. Revision to DOE Order 450.1 [1] and How it affects DOE Sites

    International Nuclear Information System (INIS)

    Birchfield, J.W.

    2009-01-01

    On June 4, 2008, DOE finalized the latest technical revision of DOE Order 450.1A. The latest revision of the order contains many new EMS requirements that can have a dramatic effect on what and how activities are conducted at the various DOE sites. The latest revision of the order contains many new Environmental Management System (EMS) requirements that can have a dramatic effect on what and how activities are conducted at the various DOE sites. DOE Order 450.1 contains some major technical revisions that will directly affect each DOE site. The exact extent of the changes to the order will vary at each site depending on the status of EMS implementation utilizing the ISO 14001:2004 (2004 denotes the latest version in effect) Standard and Executive Order 13423. ISO 14001:2004 contains a total of 17 elements (i.e., requirements) that are required for EMS programs. Because the original DOE Order 450.1 did not require conformance to the original ISO 14001:1996 Standard, this is a significant addition to EMS program management. Some EMS program elements will require effort, some significant, depending upon the complexity of the operations conducted at the various DOE sites. Significant EMS elements added include audit programs (e.g., internal and external), operational controls (e.g., procedures, personnel and equipment), monitoring and measurement (e.g., key environmental metrics tracking and equipment calibration), document controls, communication and preventive actions. DOE has also drastically altered its approach to sustainable development and environmental stewardship by specifying departmental goals through: - Reduction or elimination of the toxicity of waste through pollution prevention; - Reduction or elimination of the acquisition, use and release of toxic/hazardous materials and chemicals; - Maximizing the purchase of environmental friendly chemicals and materials in the conduct of operations; - Reduction or elimination of environmental impacts from electronic

  11. Quality Assurance Grading Guidelines for Research and Development at DOE Facilities (DOE Order 5700.6C)

    Energy Technology Data Exchange (ETDEWEB)

    Powell, T.B.

    1992-01-01

    The quality assurance (QA) requirements for the U.S. Department of Energy (DOE) are established in DOE Order 5700.6C. This order is applicable for all DOE departmental elements, management, and maintenance and operating contractors and requires that documented Quality Assurance Programs (QAPs) are prepared at all levels; it has one attachment. The DOE Office of Energy Research (DOE-ER) has issued a standard to ensure implementation of the full intent of this order in the ER community.

  12. Quality assurance grading guidelines for research and development at DOE facilities. DOE Order 5700.6C

    Energy Technology Data Exchange (ETDEWEB)

    Powell, T.B.; Morris, R.N.

    1992-10-01

    The quality assurance (QA) requirements for the US Department of Energy (DOE) are established in DOE Order 5700.6C. This order is applicable for all DOE departmental elements, management, and maintenance and operating contractors and requires that documented Quality Assurance Programs (QAPS) are prepared at all levels; it has one attachment. The DOE Office of Energy Research (DOE-ER) has issued a standard to ensure implementation of the full intent of this order in the ER community. This report discusses order 5700.6C in relation to research with DOE.

  13. Richland Operations Office (DOE-RL) Implementation Plan for DOE Order 435.1

    International Nuclear Information System (INIS)

    FRITZ, D.W.

    2000-01-01

    The U.S. Department of Energy issued U.S. Department of Energy Order 435.1, Radioactive Waste Management, and U.S. Department of Energy Manual 435.1-1, Radioactive Waste Management Manual, on July 9, 1999, to replace U.S. Department of Energy Order 5820.2A. Compliance is required by July 9, 2000, where compliance is defined as ''implementing the requirements, or an approved implementation, or corrective action plan'' (refer to Manual, Introduction, paragraph four). This implementation plan identifies the status of each requirement for U.S. Department of Energy, Richland Operations Office Site contractors, and provides the plan, cost, and length of time required for achieving full implementation. The U.S. Department of Energy, Richland Operations Office contractors (Fluor Hanford, Incorporated, DynCorp Tri-Cities Services, Bechtel Hanford, Inc., and Pacific Northwest National Laboratory) conducted a line-by-line review of DOE Order 435.1 and associated manuals to determine which requirements were new, and which requirements already are used for compliance with the previous DOE Order 5820.2A or other requirements. The Gap Analysis for DOE Order 435.1 (HNF-5465) identified compliance gaps, along with other issues that would impact efforts for achieving compliance. The gap analysis also contained a series of assumptions made by the various projects in determining compliance status. The details and section-by-section analysis are contained in Appendix A. Some of the DOE Order 435.1 requirements invoke sections of other DOE Orders not incorporated in various U.S. Department of Energy, Richland Operations Office contracts (refer to Section 2.0, Table 2-1). Those additional DOE Orders are identified by contractor and will be left for evaluation in accordance with each contractor's requirements. No attempt was made to evaluate all of those orders at this time, although in many cases, contractors follow a similar older DOE Order, which is cited in the Appendix. In some areas

  14. Comparative analysis of DOE Order 5820.2A, NRC, and EPA radioactive and mixed waste management requirements

    International Nuclear Information System (INIS)

    1991-07-01

    As directed by DOE-Headquarters and DOE-Idaho, the Radioactive Waste Technical Support Program (TSP) drafted an analysis of DOE Order 5820. 2A on ''Radioactive Waste Management'' to develop guidelines and criteria for revising the Order. This comparative matrix is a follow up to the earlier analysis. This matrix comparing the requirements of DOE Order 5820.2A with Nuclear Regulatory Commission (NRC) and Environmental Protection Agency (EPA) regulations was prepared at the request of EM-30. The matrix compares DOE Order 5820.2A with the following: NRC regulations in 10 CFR Part 61 on ''Licensing Requirements for Land Disposal of Radioactive Waste''; NRC regulations in 10 CFR Part 60 on ''Disposal of High-Level Radioactive Waste in Geologic Repositories''; EPA regulations in 40 CFR Part 191 on ''Environmental Radiation Protection Standards for Management and Disposal of Spent Nuclear Fuel, High-Level and Transuranic Radioactive Waste''; EPA regulations in 40 FR Part 192 on ''Health and Environmental Protection Standards for Uranium and Thorium Mill Tailing''; and EPA regulations under the Resource Conservation and Recovery Act

  15. Choosing to regulate: does choice enhance craving regulation?

    Science.gov (United States)

    Mobasser, Arian; Zeithamova, Dagmar; Pfeifer, Jennifer H

    2018-01-01

    Abstract Goal-directed behavior and lifelong well-being often depend on the ability to control appetitive motivations, such as cravings. Cognitive reappraisal is an effective way to modulate emotional states, including cravings, but is often studied under explicit instruction to regulate. Despite the strong prediction from Self-Determination Theory that choice should enhance task engagement and regulation success, little is known empirically about whether and how regulation is different when participants choose (vs are told) to exert control. To investigate how choice affects neural activity and regulation success, participants reappraised their responses to images of personally-craved foods while undergoing functional neuroimaging. Participants were either instructed to view or reappraise (‘no-choice’) or chose freely to view or reappraise (‘yes-choice’). Choice increased activity in the frontoparietal control network. We expected this activity would be associated with increased task engagement, resulting in better regulation success. However, contrary to this prediction, choice slightly reduced regulation success. Follow-up multivariate functional neuroimaging analyses indicated that choice likely disrupted allocation of limited cognitive resources during reappraisal. While unexpected, these results highlight the importance of studying upstream processes such as regulation choice, as they may affect the ability to regulate cravings and other emotional states. PMID:29462475

  16. 49 CFR 40.1 - Who does this regulation cover?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Who does this regulation cover? 40.1 Section 40.1 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL... is intended to supersede or conflict with the implementation of the Federal Railroad Administration's...

  17. Parent-Child Quality Time: Does Birth Order Matter?

    Science.gov (United States)

    Price, Joseph

    2008-01-01

    Using data from the American Time Use Survey, I find that a first-born child receives 20-30 more minutes of quality time each day with his or her parent than a second-born child of the same age from a similar family. The birth-order difference results from parents giving roughly equal time to each child at any point in time while the amount of…

  18. Integrating total quality management principles with the requirements of DOE Order 5700.6C

    Energy Technology Data Exchange (ETDEWEB)

    Hedges, D. [Scientific Ecology Group, Inc. (United States)

    1993-03-01

    The Department of Energy has recently required its field offices, contractors, and subcontractors to implement DOE Order 5700.6C, ``Quality Assurance,`` for all work on waste management contracts. The order restructures the 18 criteria of NQA-1 and focuses on the role of management in achieving and assuring quality, performance of activities to achieve and assure quality, and management`s assessment of its performance for the purpose of identifying improvements to be made. The DOE order also introduces elements of the total quality management (TQM) philosophy, which were not present in DOE Order 5700.6B. The research community within DOE has recently issued a document entitled DOE Order 5700.6C Implementation Guide, which is more explicit about the integration of TQM principles with the implementation of DOE Order 5700.6C in research facilities. The Environmental Protection Agency is sponsoring a quality assurance standard (ANSI/ASQC E-4) to replace EPA`s QAMS 005/80. The new standard is consistent with DOE Order 5700.6C, and it also stresses the integration of TQM principles within the quality assurance process. This paper discusses the intent and philosophy of the 10 criteria of the new DOE order, the status of ANSI/ASQC E-4, and how to effectively integrate TQM principles into the quality assurance process as the conversion is made from NQA-1 to DOE Order 5700.6C. The purpose and value of DOE Order 5700.6C Implementation Guide for research will also be discussed.

  19. Regulating Ultrasound Cavitation in order to Induce Reproducible Sonoporation

    Science.gov (United States)

    Mestas, J.-L.; Alberti, L.; El Maalouf, J.; Béra, J.-C.; Gilles, B.

    2010-03-01

    Sonoporation would be linked to cavitation, which generally appears to be a non reproducible and unstationary phenomenon. In order to obtain an acceptable trade-off between cell mortality and transfection, a regulated cavitation generator based on an acoustical cavitation measurement was developed and tested. The medium to be sonicated is placed in a sample tray. This tray is immersed in in degassed water and positioned above the face of a flat ultrasonic transducer (frequency: 445 kHz; intensity range: 0.08-1.09 W/cm2). This technical configuration was admitted to be conducive to standing-wave generation through reflection at the air/medium interface in the well thus enhancing the cavitation phenomenon. Laterally to the transducer, a homemade hydrophone was oriented to receive the acoustical signal from the bubbles. From this spectral signal recorded at intervals of 5 ms, a cavitation index was calculated as the mean of the cavitation spectrum integration in a logarithmic scale, and the excitation power is automatically corrected. The device generates stable and reproducible cavitation level for a wide range of cavitation setpoint from stable cavitation condition up to full-developed inertial cavitation. For the ultrasound intensity range used, the time delay of the response is lower than 200 ms. The cavitation regulation device was evaluated in terms of chemical bubble collapse effect. Hydroxyl radical production was measured on terephthalic acid solutions. In open loop, the results present a great variability whatever the excitation power. On the contrary the closed loop allows a great reproducibility. This device was implemented for study of sonodynamic effect. The regulation provides more reproducible results independent of cell medium and experimental conditions (temperature, pressure). Other applications of this regulated cavitation device concern internalization of different particles (Quantum Dot) molecules (SiRNA) or plasmids (GFP, DsRed) into different

  20. Gaseous diffusion plant transition from DOE to external regulation

    International Nuclear Information System (INIS)

    Dann, R.K.; Crites, T.R.; Rahm-Crites, L.K.

    1997-01-01

    After many years of operation as government-owned/contractor-operated facilities, large portions of the gaseous diffusion plants (GDPs) at Portsmouth, Ohio, and Paducah, Kentucky, were leased to the United States Enrichment Corporation (USEC). These facilities are now certified by the U.S. Nuclear Regulatory Commission (NRC) and subject to oversight by the Occupational Safety and Health Administration (OSHA). The transition from DOE to NRC regulation was more difficult than expected. The original commitment was to achieve NRC certification in October 1995; however, considerably more time was required and transition-related costs escalated. The Oak Ridge Operations Office originally estimated the cost of transition at $60 million; $240 million has been spent to date. The DOE's experience in transitioning the GDPs to USEC operation with NRC oversight provides valuable lessons (both positive and negative) that could be applied to future transitions

  1. Canister storage building compliance assessment DOE Order 6430.1A, General Design Criteria

    International Nuclear Information System (INIS)

    BLACK, D.M.

    1999-01-01

    This document presents the Project's position on compliance with DOE Order 6430.1A ''General Design Criteria.'' No non-compliances are shown. The compliance statements have been reviewed and approved by DOE. Open items are scheduled to be closed prior to project completion

  2. DOE Order 5480.28 natural phenomena hazards mitigation system, structure, component database

    International Nuclear Information System (INIS)

    Conrads, T.J.

    1997-01-01

    This document describes the Prioritization Phase Database that was prepared for the Project Hanford Management Contractors to support the implementation of DOE Order 5480.28. Included within this document are three appendices which contain the prioritized list of applicable Project Hanford Management Contractors Systems, Structures, and Components. These appendices include those assets that comply with the requirements of DOE Order 5480.28, assets for which a waiver will be recommended, and assets requiring additional information before compliance can be ascertained

  3. Fluor Daniel Hanford implementation plan for DOE Order 5480.28. Natural phenomena hazards mitigation

    International Nuclear Information System (INIS)

    Conrads, T.J.

    1997-01-01

    Natural phenomena hazards (NPH) are unexpected acts of nature that pose a threat or danger to workers, the public, or the environment. Earthquakes, extreme winds (hurricane and tornado), snow, flooding, volcanic ashfall, and lightning strikes are examples of NPH that could occur at the Hanford Site. U.S. Department of Energy (DOE) policy requires facilities to be designed, constructed, and operated in a manner that protects workers, the public, and the environment from hazards caused by natural phenomena. DOE Order 5480.28, Natural Phenomena Hazards Mitigation, includes rigorous new natural phenomena criteria for the design of new DOE facilities, as well as for the evaluation and, if necessary, upgrade of existing DOE facilities. The Order was transmitted to Westinghouse Hanford Company in 1993 for compliance and is also identified in the Project Hanford Management Contract, Section J, Appendix C. Criteria and requirements of DOE Order 5480.28 are included in five standards, the last of which, DOE-STD-1023, was released in fiscal year 1996. Because the Order was released before all of its required standards were released, enforcement of the Order was waived pending release of the last standard and determination of an in-force date by DOE Richland Operations Office (DOE-RL). Agreement also was reached between the Management and Operations Contractor and DOE-RL that the Order would become enforceable for new structures, systems, and components (SSCS) 60 days following issue of a new order-based design criteria in HNF-PRO-97, Engineering Design and Evaluation. The order also requires that commitments addressing existing SSCs be included in an implementation plan that is to be issued 1 year following the release of the last standard. Subsequently, WHC-SP-1175, Westinghouse Hanford Company Implementation Plan for DOE Order 5480.28, Natural Phenomena Hazards Mitigation, Rev. 0, was issued in November 1996, and this document, HNF-SP-1175, Fluor Daniel Hanford

  4. Planned revision to DOE Order 5820.2A, Radioactive Waste Management

    Energy Technology Data Exchange (ETDEWEB)

    Duggan, G.J. [Dept. of Energy, Washington, DC (United States); Williams, R.E.; Kudera, D.E. [EG and G Idaho, Inc., Idaho Falls, ID (United States). Idaho National Engineering Lab.; Bailey, D.E. [NJG, Inc. (United States)

    1993-03-01

    US Department of Energy Headquarters initiated efforts to revise DOE Order 5820.2A, ``Radioactive Waste Management``. The purpose of the revision is to enhance DOE waste management requirements, reflect new DOE organizational responsibilities, and consolidate requirements for management of all waste, under the responsibility of Environmental Restoration and Waste Management, into a single order. This paper discusses the revision philosophy, objectives of the revision, and strategy for the revision. Issues being considered for inclusion in the revision and recommended methods of resolving each issue are also discussed.

  5. Improving the regulation of safety at DOE nuclear facilities. Final report: Appendices

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-01

    The report strongly recommends that, with the end of the Cold War, safety and health at DOE facilities should be regulated by outside agencies rather than by any regulatory scheme, DOE must maintain a strong internal safety management system; essentially all aspects of safety at DOE`s nuclear facilities should be externally regulated; and existing agencies rather than a new one should be responsible for external regulation.

  6. Improving the regulation of safety at DOE nuclear facilities. Final report

    International Nuclear Information System (INIS)

    1995-12-01

    The report strongly recommends that, with the end of the Cold War, safety and health at DOE facilities should be regulated by outside agencies rather than by DOE itself. The three major recommendations are: under any regulatory scheme, DOE must maintain a strong internal safety management system; essentially all aspects of safety at DOE's nuclear facilities should be externally regulated; and existing agencies rather than a new one should be responsible for external regulation

  7. Construction safety management guide for use with DOE Order 440.1

    International Nuclear Information System (INIS)

    1997-01-01

    DOE Order (DOE O) 440.1, Worker Protection Management for DOE Federal and Contractor Employees, establishes the framework for an effective worker protection program to reduce or eliminate accidental losses, injuries, and illnesses by providing workers with places of employment free of recognized hazards. In addition to prescribing program requirements applicable to all activities performed by DOE and its contractors, DOE O 440.1 provides specific requirements applicable only to construction activities. The intent of these construction-specific requirements is to compel the proactive management of construction safety on a project-by-project basis and, to the greatest extent possible, integrate the management of safety and health, both in terms of project personnel and management methodologies, with the management of the other primary elements of construction project performance: quality, cost and schedule

  8. Idaho CERCLA Disposal Facility Complex Compliance Demonstration for DOE Order 435.1

    Energy Technology Data Exchange (ETDEWEB)

    Simonds, J.

    2007-11-06

    This compliance demonstration document provides an analysis of the Idaho CERCLA Disposal Facility (ICDF) Complex compliance with DOE Order 435.1. The ICDF Complex includes the disposal facility (landfill), evaporation pond, administration facility, weigh scale, and various staging/storage areas. These facilities were designed and constructed to be compliant with DOE Order 435.1, Resource Conservation and Recovery act Subtitle C, and Toxic Substances Control Act polychlorinated biphenyl design and construction standards. The ICDF Complex is designated as the Idaho National Laboratory (INL) facility for the receipt, staging/storage, treatment, and disposal of INL Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) waste streams.

  9. Improving the regulation of safety at DOE nuclear facilities. Final report: Appendices

    International Nuclear Information System (INIS)

    1995-12-01

    The report strongly recommends that, with the end of the Cold War, safety and health at DOE facilities should be regulated by outside agencies rather than by any regulatory scheme, DOE must maintain a strong internal safety management system; essentially all aspects of safety at DOE's nuclear facilities should be externally regulated; and existing agencies rather than a new one should be responsible for external regulation

  10. 77 FR 2679 - Defense Federal Acquisition Regulation Supplement: Order of Application for Modifications

    Science.gov (United States)

    2012-01-19

    ... following methods: [cir] Regulations.gov : http://www.regulations.gov . Submit comments via the Federal e... contract. In order to determine the sequence of modifications to a contract or order, a method for... the numeric order of the modifications to a contract is not the order in which the changes to the...

  11. BASELINE DEVELOPMENT USING THE CRITICAL DECISION AND DOE ORDER 413.3 FRAMEWORKS: A CASE STUDY

    International Nuclear Information System (INIS)

    Darnell, M.L.; Duffy, M.A.; Gantos, N.J.; Zadeh, B.

    2003-01-01

    From 1943 through 1986, Battelle Memorial Institute performed nuclear research and development on behalf of various Federal government agencies, primarily for the U.S. Department of Energy (DOE) and its predecessor agencies. This work was performed in Battelle's privately owned facilities in Columbus, Ohio, and a research park located at an 11-acre facility 16 miles west of Columbus, in a rural area near the village of West Jefferson, Ohio. Under the Battelle Columbus Laboratories Decommissioning Project (BCLDP), Battelle is now engaged in cleaning up the West Jefferson site on a cost-sharing basis with the DOE. The BCLDP mission is to decontaminate Battelle facilities in a safe, environmentally sound, and cost-effective manner, returning the facilities to a condition suitable for use without radiological restriction. The Columbus Environmental Management Project (CEMP), reporting to the DOE Ohio Field Office, is the DOE organization that is responsible for overseeing the BCLDP. CEMP requested preparation of a technical baseline, suitable for independent validation, establishing the scope, cost, and schedule for completing the project. Concurrent with this request, the DOE Office of Environmental Management issued DOE Order 413.3, Program and Project Management for the Acquisition of Capital Assets, for review and, shortly thereafter, published the first drafts of companion documents titled Program and Project Management Manual and Project Management Practices. These two documents suggest or require the use of a variety of techniques and tools for planning and executing DOE cleanup programs. Accordingly, Battelle successfully developed a project baseline for obtaining approval of Critical Decision 2/3 (CD-2/3) in compliance with the requirements of DOE Order 413.3 and the technical approaches described in the companion documents. This paper addresses three fundamental questions:(1) What were the planned baseline development methodology and its implementation

  12. Guidance document for revision of DOE Order 5820.2A, Radioactive Waste Technical Support Program

    International Nuclear Information System (INIS)

    Kudera, D.E.; McMurtrey, C.D.; Meagher, B.G.

    1993-04-01

    This document provides guidance for the revision of DOE Order 5820.2A, ''Radioactive Waste Management.'' Technical Working Groups have been established and are responsible for writing the revised order. The Technical Working Groups will use this document as a reference for polices and procedures that have been established for the revision process. The overall intent of this guidance is to outline how the order will be revised and how the revision process will be managed. In addition, this document outlines technical issues considered for inclusion by a Department of Energy Steering Committee

  13. Robust Fuzzy Control for Fractional-Order Uncertain Hydroturbine Regulating System with Random Disturbances

    OpenAIRE

    Fengjiao Wu; Guitao Zhang; Zhengzhong Wang

    2016-01-01

    The robust fuzzy control for fractional-order hydroturbine regulating system is studied in this paper. First, the more practical fractional-order hydroturbine regulating system with uncertain parameters and random disturbances is presented. Then, on the basis of interval matrix theory and fractional-order stability theorem, a fuzzy control method is proposed for fractional-order hydroturbine regulating system, and the stability condition is expressed as a group of linear matrix inequalities. ...

  14. A conceptual framework for using DOE 5700.6C and the other DOE orders as an integrated management system; the Fermilab experience

    International Nuclear Information System (INIS)

    Bodnarczuk, M.

    1992-06-01

    In this paper, I describe a conceptual framework that uses DOE Order 5700.6C and more than 140 other DOE Orders as an integrated management system -- but I describe it within the context of the broader sociological and cultural issues of doing research at DOE funded facilities. The conceptual framework has two components. The first involves an interpretation of the 10 criteria of DOE 5700.6C that is tailored for a research environment. The second component involves using the 10 criteria as functional categories that orchestrate and integrate the other DOE Orders into a total management system. The Fermilab approach aims at reducing (or eliminating) the redundancy and overlap within the DOE Orders system at the contractor level

  15. A conceptual framework for using DOE 5700. 6C and the other DOE orders as an integrated management system; the Fermilab experience

    Energy Technology Data Exchange (ETDEWEB)

    Bodnarczuk, M.

    1992-06-01

    In this paper, I describe a conceptual framework that uses DOE Order 5700.6C and more than 140 other DOE Orders as an integrated management system -- but I describe it within the context of the broader sociological and cultural issues of doing research at DOE funded facilities. The conceptual framework has two components. The first involves an interpretation of the 10 criteria of DOE 5700.6C that is tailored for a research environment. The second component involves using the 10 criteria as functional categories that orchestrate and integrate the other DOE Orders into a total management system. The Fermilab approach aims at reducing (or eliminating) the redundancy and overlap within the DOE Orders system at the contractor level.

  16. A conceptual framework for using DOE 5700.6C and the other DOE orders as an integrated management system; the Fermilab experience

    Energy Technology Data Exchange (ETDEWEB)

    Bodnarczuk, M.

    1992-06-01

    In this paper, I describe a conceptual framework that uses DOE Order 5700.6C and more than 140 other DOE Orders as an integrated management system -- but I describe it within the context of the broader sociological and cultural issues of doing research at DOE funded facilities. The conceptual framework has two components. The first involves an interpretation of the 10 criteria of DOE 5700.6C that is tailored for a research environment. The second component involves using the 10 criteria as functional categories that orchestrate and integrate the other DOE Orders into a total management system. The Fermilab approach aims at reducing (or eliminating) the redundancy and overlap within the DOE Orders system at the contractor level.

  17. 30 CFR 285.1000 - What activities does this subpart regulate?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What activities does this subpart regulate? 285.1000 Section 285.1000 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... Activities § 285.1000 What activities does this subpart regulate? (a) This subpart provides the general...

  18. ORNL implementation of new health and safety requirements (DOE Order 5480.11)

    International Nuclear Information System (INIS)

    Abercrombie, J.S.

    1988-01-01

    New mandates in radiological protection outlined in DOE Order 5480. 11, include changes in the methodology for determining total radiation dose, ALARA program accountability, monitoring requirements, and standards for public entrance into controlled areas. The new order places distinct requirements concerning training at all DOE facilities. Radiation protection training requirements are addressed, including the effective communication of operations changes to all employees. This paper details the endeavors underway at ORNL in designing, developing, and delivering the training required by the new mandates. Strategies taken to reach the intended goals are explained. Efforts involve the design and implementation of the above mentioned radiation protection programs, a job-specific ALARA instructional package, and a Risk-Based Philosophy program matched to operational changes. 4 refs., 5 tabs

  19. References for HNF-SD-WM-TRD-007, ''System specification for the double-shell tank system: HNF-PROs, CFRs, DOE Orders, WACs''

    International Nuclear Information System (INIS)

    Shaw, C.P.

    1998-01-01

    HNF-SD-WM-TRD-O07, System Specification for the Double-Shell Tank System, (hereafter referred to as DST Specification), defines the requirements of the double-shell tank system at the Hanford Site for Phase 1 privatization. Many of the sections in this document reference other documents for design guidance and requirements. Referenced documents include Project Hanford Management Contract (PHMC) procedures (HNF-PROS), Codes of Federal Regulation (CFRs), DOE Orders, and Washington Administrative Codes (WACs). This document provides rationale for the selection and inclusion of HNF-PROS, CFRs, DOE Orders and WACs

  20. Does self-regulation of advertisement length improve consumer welfare?

    OpenAIRE

    Matsubae, Taisuke; Matsushima, Noriaki

    2012-01-01

    In Japan, TV platforms regulate themselves as to the length of the advertisements they air. Using modified Hotelling models, we investigate whether such self-regulation improves consumer and social welfare or not. When all consumers choose a single TV program (the utility functions of consumers satisfy the standard 'full-coverage' condition), self-regulation always reduces consumer welfare. It improves social welfare only if the advertisement revenue of each platform is not small and the cost...

  1. 19 CFR 12.10 - Regulations and orders of the Department of Agriculture.

    Science.gov (United States)

    2010-04-01

    ... Agriculture. 12.10 Section 12.10 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND... Regulations and orders of the Department of Agriculture. The importation into the United States of plants and plant products is subject to regulations and orders of the Department of Agriculture restricting or...

  2. 25 CFR 900.50 - What Federal laws, regulations, and Executive Orders apply to subcontractors?

    Science.gov (United States)

    2010-04-01

    ... SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Standards for Tribal or Tribal Organization Management..., regulations, and Executive Orders apply to subcontracts awarded under self-determination contracts. As a... 25 Indians 2 2010-04-01 2010-04-01 false What Federal laws, regulations, and Executive Orders...

  3. Robust Fuzzy Control for Fractional-Order Uncertain Hydroturbine Regulating System with Random Disturbances

    Directory of Open Access Journals (Sweden)

    Fengjiao Wu

    2016-01-01

    Full Text Available The robust fuzzy control for fractional-order hydroturbine regulating system is studied in this paper. First, the more practical fractional-order hydroturbine regulating system with uncertain parameters and random disturbances is presented. Then, on the basis of interval matrix theory and fractional-order stability theorem, a fuzzy control method is proposed for fractional-order hydroturbine regulating system, and the stability condition is expressed as a group of linear matrix inequalities. Furthermore, the proposed method has good robustness which can process external random disturbances and uncertain parameters. Finally, the validity and superiority are proved by the numerical simulations.

  4. Does drug price-regulation affect healthcare expenditures?

    Science.gov (United States)

    Ben-Aharon, Omer; Shavit, Oren; Magnezi, Racheli

    2017-09-01

    Increasing health costs in developed countries are a major concern for decision makers. A variety of cost containment tools are used to control this trend, including maximum price regulation and reimbursement methods for health technologies. Information regarding expenditure-related outcomes of these tools is not available. To evaluate the association between different cost-regulating mechanisms and national health expenditures in selected countries. Price-regulating and reimbursement mechanisms for prescription drugs among OECD countries were reviewed. National health expenditure indices for 2008-2012 were extracted from OECD statistical sources. Possible associations between characteristics of different systems for regulation of drug prices and reimbursement and health expenditures were examined. In most countries, reimbursement mechanisms are part of publicly financed plans. Maximum price regulation is composed of reference-pricing, either of the same drug in other countries, or of therapeutic alternatives within the country, as well as value-based pricing (VBP). No association was found between price regulation or reimbursement mechanisms and healthcare costs. However, VBP may present a more effective mechanism, leading to reduced costs in the long term. Maximum price and reimbursement mechanism regulations were not found to be associated with cost containment of national health expenditures. VBP may have the potential to do so over the long term.

  5. Does business regulation matter for banks in the European Union?

    OpenAIRE

    Kalyvas, Nikolaos Antonios; Mamatzakis, Emmanuel

    2014-01-01

    This paper provides a comprehensive analysis of the impact of business and financial specific regulations on banks in the EU-27 over the 2004–2010 period. We employ a dataset of a wide range of business regulation indices from the “Doing Business” project of the World Bank. Results for the credit regulation indices show that the strength of creditor rights is negatively related to bank performance as measured by cost efficiency, although this effect subdues during the recent crisis period (20...

  6. Waste Cleanup: Status and Implications of Compliance Agreements Between DOE and Its Regulators

    International Nuclear Information System (INIS)

    Jones, G. L.; Swick, W. R.; Perry, T. C.; Kintner-Meyer, N.K.; Abraham, C. R.; Pollack, I. M.

    2003-01-01

    This paper discusses compliance agreements that affect the Department of Energy's (DOE) cleanup program. Compliance agreements are legally enforceable documents between DOE and its regulators, specifying cleanup activities and milestones that DOE has agreed to achieve. Over the years, these compliance agreements have been used to implement much of the cleanup activity at DOE sites, which is carried our primarily under two federal laws - the Comprehensive Environmental Response, Compensation, and Liability Act of 1980, as amended (CERCLA) and the Resource Conservation and Recovery Act of 0f 1976, as amended (RCRA). Our objectives were to determine the types of compliance agreements in effect at DOE cleanup sites, DOE's progress in achieving the milestones contained in the agreements, whether the agreements allowed DOE to prioritize work across sites according to relative risk, and possible implications the agreements have on DOE's efforts to improve the cleanup program

  7. Environmental monitoring guidance for DOE Order 5820.2A, Chapter 3

    International Nuclear Information System (INIS)

    Dolenc, M.R.

    1988-01-01

    The Defense Low-Level Waste Management Program (DLLWMP) is preparing guidance to support the requirements outlined in DOE Order 5820.2A, Chapter 3, Management of Low-Level Waste. One of these documents is the Environmental Monitoring Guidance. Environmental monitoring is required for all operational and nonoperational treatment, storage, and disposal facilities to ensure that the facility conforms to all appropriate DOE orders. An adequate environmental monitoring program must be designed to measure key parameters that may affect both short- and long-term site performance. These parameters include measuring both chemical and radiological releases in surface soil, air, surface water, flora, fauna, and subsurface soil and groundwater, both in the saturated and unsaturated zones. The monitoring program must be capable of detecting performance trends in sufficient time to allow corrective action before the facility exceeds performance objectives. The program should also provide the data input necessary to evaluate the performance assessment of the facility. This paper outlines the approach being planned to accomplish these tasks

  8. Idaho CERCLA Disposal Facility Complex Compliance Demonstration for DOE Order 435.1

    Energy Technology Data Exchange (ETDEWEB)

    J. Simonds

    2006-09-01

    This compliance demonstration document provides an analysis of the Idaho CERCLA Disposal Facility (ICDF) Complex compliance with DOE Order 435.1. The ICDF Complex includes the disposal facility (landfill), evaporation pond, admin facility, weigh scale, decon building, treatment systems, and various staging/storage areas. These facilities were designed and are being constructed to be compliant with DOE Order 435.1, Resource Conservation and Recovery Act Subtitle C, and Toxic Substances Control Act polychlorinated biphenyl design and construction standards. The ICDF Complex is designated as the central Idaho National Laboratory (INL) facilityyy for the receipt, staging/storage, treatment, and disposal of INL Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) waste streams. This compliance demonstration document discusses the conceptual site model for the ICDF Complex area. Within this conceptual site model, the selection of the area for the ICDF Complex is discussed. Also, the subsurface stratigraphy in the ICDF Complex area is discussed along with the existing contamination beneath the ICDF Complex area. The designs for the various ICDF Complex facilities are also included in this compliance demonstration document. These design discussions are a summary of the design as presented in the Remedial Design/Construction Work Plans for the ICDF landfill and evaporation pond and the Staging, Storage, Sizing, and Treatment Facility. Each of the major facilities or systems is described including the design criteria.

  9. 78 FR 18342 - Federal Acquisition Regulation; Submission for OMB Review; Change Order Accounting

    Science.gov (United States)

    2013-03-26

    ...; Submission for OMB Review; Change Order Accounting AGENCY: Department of Defense (DOD), General Services... requirement concerning change order accounting. A notice was published in the Federal Register at 77 FR 51804... Collection 9000- 0026, Change Order Accounting, by any of the following methods: Regulations.gov : http://www...

  10. 77 FR 51804 - Federal Acquisition Regulation; Information Collection; Change Order Accounting

    Science.gov (United States)

    2012-08-27

    ...; Information Collection; Change Order Accounting AGENCY: Department of Defense (DOD), General Services... requirement concerning change order accounting. Public comments are particularly invited on: Whether this... 9000- 0026, Change Order Accounting by any of the following methods: Regulations.gov : http://www...

  11. Environmental regulation and MNEs location : does CSR matter?

    NARCIS (Netherlands)

    Scholtens, B.; Dam, L.

    2008-01-01

    We investigate whether firms with relatively low environmental standards are more often located in countries that are poor, corrupt or have weak environmental regulations. We find new empirical evidence in favor of the Pollution Haven Hypothesis, which states that MNEs are transferring their dirty

  12. Construction and repair of highly ordered 2D covalent networks by chemical equilibrium regulation.

    Science.gov (United States)

    Guan, Cui-Zhong; Wang, Dong; Wan, Li-Jun

    2012-03-21

    The construction of well-ordered 2D covalent networks via the dehydration of di-borate aromatic molecules was successfully realized through introducing a small amount of water into a closed reaction system to regulate the chemical equilibrium.

  13. Notification: Implementation of Executive Order 13771, “Reducing Regulation and Controlling Regulatory Costs”

    Science.gov (United States)

    Project #OA&E-FY18-0177, April 10, 2018. The OIG plans to begin preliminary research on the Office of the Administrator's Office of Policy implementation of Executive Order 13771, Reducing Regulation and Controlling Regulatory Costs.

  14. 77 FR 31549 - Child Labor Regulations, Orders and Statements of Interpretation; Child Labor Violations-Civil...

    Science.gov (United States)

    2012-05-29

    ... DEPARTMENT OF LABOR Wage and Hour Division 29 CFR Parts 570 and 579 RIN 1235-AA06 Child Labor Regulations, Orders and Statements of Interpretation; Child Labor Violations--Civil Money Penalties AGENCY... its [[Page 31550

  15. 29 CFR 790.17 - “Administrative regulation, order, ruling, approval, or interpretation.”

    Science.gov (United States)

    2010-07-01

    ... 1938 Defense of Good Faith Reliance on Administrative Regulations, Etc. § 790.17 “Administrative... in regard to their function under the “good faith” defense. Accordingly, no useful purpose would be... that where the employer's good faith reliance on a regulation, order, ruling, approval or...

  16. 77 FR 38173 - Child Labor Regulations, Orders and Statements of Interpretation

    Science.gov (United States)

    2012-06-27

    ... DEPARTMENT OF LABOR Wage and Hour Division 29 CFR Part 570 Child Labor Regulations, Orders and Statements of Interpretation CFR Correction 0 In Title 29 of the Code of Federal Regulations, Parts 500 to 899, revised as of July 1, 2011, on page 302, the section heading for Sec. 570.65 is corrected to read...

  17. 76 FR 67104 - Child Labor Regulations, Orders and Statements of Interpretation; Child Labor Violations-Civil...

    Science.gov (United States)

    2011-10-31

    ... DEPARTMENT OF LABOR Wage and Hour Division 29 CFR Parts 570 and 579 RIN 1235-AA06 Child Labor Regulations, Orders and Statements of Interpretation; Child Labor Violations--Civil Money Penalties AGENCY... child labor regulations published on September 2, 2011. The Department of Labor (Department or DOL) is...

  18. Development of an analogue multiplexed regulation for periodic 1. order delayed processes

    International Nuclear Information System (INIS)

    Amblard, J.C.

    1967-07-01

    The present note deals with the study regulations of the sampled type, for 1. order process with simple delay. In order to obtain a good stability in such regulations, together with acceptable performances, it is interesting to use polynomial type correctors acting directly on the sampled error signals. The active elements of these correctors can be shared by all the channels to be controlled. Furthermore, the determination of the correction parameters results from an optimal study of the system. In the second part is described the construction of a multiplexed regulation for diffusion ovens. (author) [fr

  19. Royal Order of 5 December 1975 amending the Royal Order of 11 May 1971 embodying the general Military Regulations for Protection Against the Hazards of Ionizing Radiations

    International Nuclear Information System (INIS)

    1975-01-01

    This Royal Order amends the Royal Order on general Military Regulations for Protection against the Hazards of Ionizing Radiations to bring it into line with the Royal Order of 23 December 1970, amending the general Regulations for Protection of the Population and Workers against the Hazards of Ionizing Radiations of 28 February 1963, subject to certain adaptations specific to military activities. (NEA) [fr

  20. Insulin regulates brain function, but how does it get there?

    Science.gov (United States)

    Gray, Sarah M; Meijer, Rick I; Barrett, Eugene J

    2014-12-01

    We have learned over the last several decades that the brain is an important target for insulin action. Insulin in the central nervous system (CNS) affects feeding behavior and body energy stores, the metabolism of glucose and fats in the liver and adipose, and various aspects of memory and cognition. Insulin may even influence the development or progression of Alzheimer disease. Yet, a number of seemingly simple questions (e.g., What is the pathway for delivery of insulin to the brain? Is insulin's delivery to the brain mediated by the insulin receptor and is it a regulated process? Is brain insulin delivery affected by insulin resistance?) are unanswered. Here we briefly review accumulated findings affirming the importance of insulin as a CNS regulatory peptide, examine the current understanding of how peripheral insulin is delivered to the brain, and identify key gaps in the current understanding of this process. © 2014 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

  1. Does Erythropoietin Regulate TRPC Channels in Red Blood Cells?

    Directory of Open Access Journals (Sweden)

    Jens Danielczok

    2017-03-01

    Full Text Available Background: Cation channels play an essential role in red blood cells (RBCs ion homeostasis. One set of ion channels are the transient receptor potential channels of canonical type (TRPC channels. The abundance of these channels in primary erythroblasts, erythroid cell lines and RBCs was associated with an increase in intracellular Ca2+ upon stimulation with Erythropoietin (Epo. In contrast two independent studies on Epo-treated patients revealed diminished basal Ca2+ concentration or reduced phosphatidylserine exposure to the outer membrane leaflet. Methods: To resolve the seemingly conflicting reports we challenged mature human and mouse RBCs of several genotypes with Epo and Prostaglandin E2 (PGE2 and recorded the intracellular Ca2+ content. Next Generation Sequencing was utilised to approach a molecular analysis of reticulocytes. Results/Conclusions: Our results allow concluding that Epo and PGE2 regulation of the Ca2+ homeostasis is distinctly different between murine and human RBCs and that changes in intracellular Ca2+ upon Epo treatment is a primary rather than a compensatory effect. In human RBCs, Epo itself has no effect on Ca2+ fluxes but inhibits the PGE2-induced Ca2+ entry. In murine mature RBCs functional evidence indicates TRPC4/C5 mediated Ca2+ entry activated by Epo whereas PGE2 leads to a TRPC independent Ca2+ entry.

  2. Drak2 Does Not Regulate TGF-β Signaling in T Cells.

    Directory of Open Access Journals (Sweden)

    Tarsha L Harris

    Full Text Available Drak2 is a serine/threonine kinase expressed highest in T cells and B cells. Drak2-/- mice are resistant to autoimmunity in mouse models of type 1 diabetes and multiple sclerosis. Resistance to these diseases occurs, in part, because Drak2 is required for the survival of autoreactive T cells that induce disease. However, the molecular mechanisms by which Drak2 affects T cell survival and autoimmunity are not known. A recent report demonstrated that Drak2 negatively regulated transforming growth factor-β (TGF-β signaling in tumor cell lines. Thus, increased TGF-β signaling in the absence of Drak2 may contribute to the resistance to autoimmunity in Drak2-/- mice. Therefore, we examined if Drak2 functioned as a negative regulator of TGF-β signaling in T cells, and whether the enhanced susceptibility to death of Drak2-/- T cells was due to augmented TGF-β signaling. Using several in vitro assays to test TGF-β signaling and T cell function, we found that activation of Smad2 and Smad3, which are downstream of the TGF-β receptor, was similar between wildtype and Drak2-/- T cells. Furthermore, TGF-β-mediated effects on naïve T cell proliferation, activated CD8+ T cell survival, and regulatory T cell induction was similar between wildtype and Drak2-/- T cells. Finally, the increased susceptibility to death in the absence of Drak2 was not due to enhanced TGF-β signaling. Together, these data suggest that Drak2 does not function as a negative regulator of TGF-β signaling in primary T cells stimulated in vitro. It is important to investigate and discern potential molecular mechanisms by which Drak2 functions in order to better understand the etiology of autoimmune diseases, as well as to validate the use of Drak2 as a target for therapeutic treatment of these diseases.

  3. The Porphyromonas gingivalis ferric uptake regulator orthologue does not regulate iron homeostasis

    Directory of Open Access Journals (Sweden)

    Catherine Butler

    2015-09-01

    Full Text Available Porphyromonas gingivalis is a Gram-negative anaerobic bacterium that has an absolute requirement for iron which it transports from the host as heme and/or Fe2+. Iron transport must be regulated to prevent toxic effects from excess metal in the cell. P. gingivalis has one ferric uptake regulator (Fur orthologue encoded in its genome called Har, which would be expected to regulate the transport and usage of iron within this bacterium. As a gene regulator, inactivation of Har should result in changes in gene expression of several genes compared to the wild-type. This dataset (GEO accession number GSE37099 provides information on expression levels of genes in P. gingivalis in the absence of Har. Surprisingly, these genes do not relate to iron homeostasis.

  4. Does electricity (and heat) network regulation have anything to learn from fixed line telecoms regulation?

    International Nuclear Information System (INIS)

    Pollitt, Michael

    2010-01-01

    The purpose of this paper is to examine the lessons from the recent history of telecoms deregulation for electricity (and by implication heat) network regulation. We do this in the context of Ofgem's RPI-X rate at 20 review of energy regulation in the UK, which considers whether RPI-X-based price regulation is fit for purpose after over 20 years of operation in energy networks. We examine the deregulation of fixed line telecoms in the UK and the lessons which it seems to suggest. We then apply the lessons to electricity networks in the context of a possible increase in distributed generation directly connected to local distribution networks. We conclude that there is the possibility of more parallels over time and suggest several implications of this for the regulation of electricity and heat networks. (author)

  5. Lessons learned in the implementation of Integrated Safety Management at DOE Order Compliance Sites vs Necessary and Sufficient Sites

    International Nuclear Information System (INIS)

    Hill, R.L.

    2000-01-01

    This paper summarizes the development and implementation of Integrated Safety Management (ISM) at an Order Compliance Site (Savannah River Site) and a Necessary and Sufficient Site (Nevada Test Site). A discussion of each core safety function of ISM is followed by an example from an Order Compliance Site and a Necessary and Sufficient Site. The Savannah River Site was the first DOE site to have a DOE Headquarters-validated and approved ISM System. The NTS is beginning the process of verification and validation. This paper defines successful strategies for integrating Environment, Safety, and Health management into work under various scenarios

  6. 78 FR 59165 - Orders: Information Reporting With Respect to Stress Testing of Regulated Entities

    Science.gov (United States)

    2013-09-26

    ... Instructions and Guidance is effective on October 28, 2013. FOR FURTHER INFORMATION CONTACT: Naa Awaa Tagoe, Senior Associate Director, Office of Financial Analysis, Modeling and Simulations, (202) 649-3140... Guidance accompanying each Order provides to the regulated entities general advice concerning the content...

  7. 28 CFR 91.68 - Compliance with other Federal environmental statutes, regulations and executive orders.

    Science.gov (United States)

    2010-07-01

    ... OF JUSTICE (CONTINUED) GRANTS FOR CORRECTIONAL FACILITIES Environmental Impact Review Procedures for VOI/TIS Grant Program Other State and Federal Law Requirements § 91.68 Compliance with other Federal environmental statutes, regulations and executive orders. (a) Other Federal environmental laws. All projects...

  8. Keeping Order: Motor-Car Regulation and the Defeat of Victoria's 1905 Motor-Car Bill

    Directory of Open Access Journals (Sweden)

    Rick Clapton

    2004-10-01

    Full Text Available At the turn of the twentieth century some upper-class Victorians became motorists; consequently, for the first time ever, regulation and policing intersected with this class of society. By 1905 so many concerns had been raised about compromised public order and safety that the Victorian State Government attempted to implement a Motor Car Bill based on its English predecessor (1903. Wealthy motorists possessed power and influence, however, which contributed to the postponement of legislation until 1910. Additionally, parliamentarians were drawn from the same social class as motorists, and, in creating regulation, they were potentially regulating their peers, colleagues and friends. The private motor-car also brought with it new issues of civil liberty and responsibility. Finding a balance between the two continued to be a problem, as private transport gradually became affordable for middle- and working-class people, and both the number of regulations and the power of the motoring lobby increased.

  9. Does regulating others' feelings influence people's own affective well-being?

    Science.gov (United States)

    Niven, Karen; Totterdell, Peter; Holman, David; Headley, Tara

    2012-01-01

    Individuals in a variety of social contexts try to regulate other people's feelings, but how does this process affect the regulators themselves? This research aimed to establish a relationship between people's use of interpersonal affect regulation and their own affective well-being. In a field study, self- and other-reported data were collected from prisoners and staff members in a therapeutic prison using two surveys separated in time. In a laboratory study, a student sample reported their affect before and after attempting to influence the feelings of talent show contestants in a role-play task. The results of both studies indicated congruent associations between the use of affect-improving and affect-worsening interpersonal affect regulation and strategy agents' affective well-being. Our findings highlight that, when performing interpersonal affect regulation, people may not be immune from the effects of their own actions.

  10. Does Who I Am or How I Regulate Matter? Consequences of Manipulation of Emotion Regulation Strategies.

    Science.gov (United States)

    Ali, Sideeka; Alea, Nicole

    2017-07-01

    This study experimentally examined the affective and social consequences of emotion regulation in men and women from young adulthood to old age. Participants were instructed to reappraise, suppress, or given no instructions while recalling a negative memory about their romantic relationship. Participants were 191 adults in a Trinidadian lifespan sample. Engaging in suppression resulted in higher relationship satisfaction, particularly for women, whereas engaging in reappraisal reduced negative affect for middle-aged versus younger adults. Reappraisal was, however, particularly consequential for young women who experienced higher levels of negative affect compared with men of the same age and older aged women. Regardless of instructions, older adults experienced higher relationship satisfaction, higher positive and lower negative affect than younger aged adults. Results are discussed considering the positivity effect for older adults, and how the current and historical climate of Trinidad influences the way women regulate their emotions.

  11. Berkeley Lab Pilot on External Regulation of DOE National Laboratories by the U.S. NRC

    International Nuclear Information System (INIS)

    Zeman, Gary H.

    1999-01-01

    The US Department of Energy and the US Nuclear Regulatory Commission entered into an agreement in November 1997 to pursue external regulation of radiation safety at DOE national laboratories through a Pilot Program of simulated regulation at 6-10 sites over a 2 year period. The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab), the oldest of the DOE national laboratories, volunteered and was selected as the first Pilot site. Based on the similarities and linkages between Berkeley Lab and nearby university research laboratories, Berkeley Lab seemed a good candidate for external regulation and a good first step in familiarizing NRC with the technical and institutional issues involved in regulating laboratories in the DOE complex. NRC and DOE team members visited Berkeley Lab on four occasions between October 1997 and January 1998 to carry out the Pilot. The first step was to develop a detailed Work Plan, then to carry out both a technical review of the radiation safety program and an examination of policy and regulatory issues. The Pilot included a public meeting held in Oakland, CA in December 1997. The Pilot concluded with NRC's assessment that Berkeley Lab has a radiation protection program adequate to protect workers, the public and the environment, and that it is ready to be licensed by the NRC with minor programmatic exceptions. A draft final report of the Pilot was prepared and circulated for comment as a NUREG document (dated May 7, 1998). The report's recommendations include extending NRC regulatory authority to cover all ionizing radiation sources (including accelerators, x-ray units, NARM) at Berkeley Lab. Questions remaining to be resolved include: who should be the licensee (DOE, the Lab, or both)?; dealing with legacy issues and NRC D and D requirements; minimizing dual oversight; quantifying value added in terms of cost savings, enhanced safety, and improved public perception; extrapolating results to other national laboratories; and

  12. Guidance document for revision of DOE Order 5820.2A, Radioactive Waste Technical Support Program. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Kudera, D.E.; McMurtrey, C.D.; Meagher, B.G.

    1993-04-01

    This document provides guidance for the revision of DOE Order 5820.2A, ``Radioactive Waste Management.`` Technical Working Groups have been established and are responsible for writing the revised order. The Technical Working Groups will use this document as a reference for polices and procedures that have been established for the revision process. The overall intent of this guidance is to outline how the order will be revised and how the revision process will be managed. In addition, this document outlines technical issues considered for inclusion by a Department of Energy Steering Committee.

  13. Guidance on meeting DOE order requirements for traceable nondestructive assay measurements

    International Nuclear Information System (INIS)

    1994-05-01

    Purpose of this guide is to facilitate accuracy and precision of nondestructive assay measurements through improvement of the materials and process of traceability. This document provides DOE and its contractor facilities with guidance to establish traceability to the national measurement base for site-prepared NDA working reference materials

  14. Does main clause word order affect attention to change in subordinate clauses?

    DEFF Research Database (Denmark)

    Christensen, Marie Herget; Christensen, Tanya Karoli; Jensen, Torben Juel

    2018-01-01

    ,and in the article we argue that this ‘Main Clause Phenomena’ (cf. Aelbrechtet al. 2012) functions as a foregroundingdevice, signaling that the more important information of the clause complex isto be found in the subordinate clause instead of in its matrix clause. Aprediction from the foregrounding hypothesis...... is that a subordinate clause withVerb>Adverb word order will attract more attention than a clause withAdverb>Verb word order. To test this, we conducted an experiment under the textchange paradigm. 59 students each read 24 constructions twice, each containinga subordinate clause with either Verb>Adverb or Adverb......>Verb word order.Half of the subordinate clauses were governed by a semifactive predicate (opento both word orders) and the other half by a semantically secondary sentence(in itself strongly favoring Verb>Adverb word order). Attention to thesubordinate clause was tested by measuring how disinclined...

  15. Proposed Risk-Informed Seismic Hazard Periodic Reevaluation Methodology for Complying with DOE Order 420.1C

    Energy Technology Data Exchange (ETDEWEB)

    Kammerer, Annie [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-03-01

    Department of Energy (DOE) nuclear facilities must comply with DOE Order 420.1C Facility Safety, which requires that all such facilities review their natural phenomena hazards (NPH) assessments no less frequently than every ten years. The Order points the reader to Standard DOE-STD-1020-2012. In addition to providing a discussion of the applicable evaluation criteria, the Standard references other documents, including ANSI/ANS-2.29-2008 and NUREG-2117. These documents provide supporting criteria and approaches for evaluating the need to update an existing probabilistic seismic hazard analysis (PSHA). All of the documents are consistent at a high level regarding the general conceptual criteria that should be considered. However, none of the documents provides step-by-step detailed guidance on the required or recommended approach for evaluating the significance of new information and determining whether or not an existing PSHA should be updated. Further, all of the conceptual approaches and criteria given in these documents deal with changes that may have occurred in the knowledge base that might impact the inputs to the PSHA, the calculated hazard itself, or the technical basis for the hazard inputs. Given that the DOE Order is aimed at achieving and assuring the safety of nuclear facilities—which is a function not only of the level of the seismic hazard but also the capacity of the facility to withstand vibratory ground motions—the inclusion of risk information in the evaluation process would appear to be both prudent and in line with the objectives of the Order. The purpose of this white paper is to describe a risk-informed methodology for evaluating the need for an update of an existing PSHA consistent with the DOE Order. While the development of the proposed methodology was undertaken as a result of assessments for specific SDC-3 facilities at Idaho National Laboratory (INL), and it is expected that the application at INL will provide a demonstration of the

  16. Proposed Risk-Informed Seismic Hazard Periodic Reevaluation Methodology for Complying with DOE Order 420.1C

    Energy Technology Data Exchange (ETDEWEB)

    Kammerer, Annie [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-10-01

    Department of Energy (DOE) nuclear facilities must comply with DOE Order 420.1C Facility Safety, which requires that all such facilities review their natural phenomena hazards (NPH) assessments no less frequently than every ten years. The Order points the reader to Standard DOE-STD-1020-2012. In addition to providing a discussion of the applicable evaluation criteria, the Standard references other documents, including ANSI/ANS-2.29-2008 and NUREG-2117. These documents provide supporting criteria and approaches for evaluating the need to update an existing probabilistic seismic hazard analysis (PSHA). All of the documents are consistent at a high level regarding the general conceptual criteria that should be considered. However, none of the documents provides step-by-step detailed guidance on the required or recommended approach for evaluating the significance of new information and determining whether or not an existing PSHA should be updated. Further, all of the conceptual approaches and criteria given in these documents deal with changes that may have occurred in the knowledge base that might impact the inputs to the PSHA, the calculated hazard itself, or the technical basis for the hazard inputs. Given that the DOE Order is aimed at achieving and assuring the safety of nuclear facilities—which is a function not only of the level of the seismic hazard but also the capacity of the facility to withstand vibratory ground motions—the inclusion of risk information in the evaluation process would appear to be both prudent and in line with the objectives of the Order. The purpose of this white paper is to describe a risk-informed methodology for evaluating the need for an update of an existing PSHA consistent with the DOE Order. While the development of the proposed methodology was undertaken as a result of assessments for specific SDC-3 facilities at Idaho National Laboratory (INL), and it is expected that the application at INL will provide a demonstration of the

  17. Private ordering and the rise of terms of service as cyber-regulation

    Directory of Open Access Journals (Sweden)

    Luca Belli

    2016-12-01

    Full Text Available Online communications and activities require the intermediation of numerous private entities that unilaterally define and implement their terms of service (ToS. The substantive provisions set in the ToS regulate the relationships between intermediaries and users with a binding force that may be even stronger than the one exercised by the law. Notably, we stress that internet intermediaries privately enforce their contractual regulation by shaping the architecture of the networks and platforms under their control. Such regulation and implementation do not need to rely on “traditional” public law-enforcement mechanisms and may apply in a transnational fashion. This paper argues that internet governance is witnessing the increasing centralisation of power in the hands of internet intermediaries defining private orderings. While acknowledging that ToS are an efficient and well-suited instrument to regulate the online world, we claim that ToS unilaterally impose rules, despite being presented as voluntarily accepted by the involved parties through the expression of free and informed consent. Based on empirical research, we highlight that ToS and their private implementation affect internet users’ capability to enjoy their human rights, with particular regard to freedom of expression (and innovation, the right to privacy and to due process. Lastly, we put forward some recommendations on internet intermediaries’ compliance with human rights standards.

  18. 78 FR 78694 - Orders: Supplemental Orders on Reporting by Regulated Entities of Stress Testing Results as of...

    Science.gov (United States)

    2013-12-27

    ... reporting under section 165(i)(2) of the Dodd-Frank Wall Street Reform and Consumer Protection Act (Dodd... testing. II. Orders For the convenience of the affected parties, the text of the Supplemental Orders... Reform and Consumer Protection Act (``Dodd-Frank Act'') requires certain financial companies with total...

  19. Does cation ordering in omphacite influence development of lattice-referred orientation?

    Czech Academy of Sciences Publication Activity Database

    Ulrich, Stanislav; Mainprice, D.

    2005-01-01

    Roč. 27, č. 3 (2005), s. 419-431 ISSN 0191-8141 R&D Projects: GA ČR GP205/03/P065 Institutional research plan: CEZ:AV0Z30120515 Keywords : clinopyroxene * lattice-preferred orientation * cation ordering Subject RIV: DB - Geology ; Mineralogy Impact factor: 2.109, year: 2005

  20. What does education have to do with the New International Economic Order

    Science.gov (United States)

    Emmerij, Louis

    1982-12-01

    Greater equality in the distribution of incomes, both nationally and internationally, and more intervention to achieve this, both by national governments and international agencies, are identified as the key ideas in the proposed NIEO. Both ideas have provoked a reaction of new conservatism, aided by the current international recession. At least in part, the power of this reaction is the result of a failure in the educational professions and institutions to respond to the requirements of an NIEO in both domestic and global terms. Although the independent effects of education on social change and income distribution have indeed been over-estimated, it remains true, nevertheless, that education does have social and economic effects. Within states, education might be reorganized so as to dissolve the current dichotomy between a `learning' childhood/adolescence and a `non-learning' adulthood. Rather, learning geared to economic activity, change and restructuring might assist both developing and industrialized states to increase incomes and adjust to the requirements of the NIEO. On the international plane, the growth of development studies and of institutions concerned with the domestic effects of international relations and commerce should facilitate a more informed understanding of the balance between self-reliance and interdependence.

  1. A reverse order interview does not aid deception detection regarding intentions.

    Science.gov (United States)

    Fenn, Elise; McGuire, Mollie; Langben, Sara; Blandón-Gitlin, Iris

    2015-01-01

    Promising recent research suggests that more cognitively demanding interviews improve deception detection accuracy. Would these cognitively demanding techniques work in the same way when discriminating between true and false future intentions? In Experiment 1 participants planned to complete a task, but instead were intercepted and interviewed about their intentions. Participants lied or told the truth, and were subjected to high (reverse order) or low (sequential order) cognitive load interviews. Third-party observers watched these interviews and indicated whether they thought the person was lying or telling the truth. Subjecting participants to a reverse compared to sequential interview increased the misidentification rate and the appearance of cognitive load in truth tellers. People lying about false intentions were not better identified. In Experiment 2, a second set of third-party observers rated behavioral cues. Consistent with Experiment 1, truth tellers, but not liars, exhibited more behaviors associated with lying and fewer behaviors associated with truth telling in the reverse than sequential interview. Together these results suggest that certain cognitively demanding interviews may be less useful when interviewing to detect false intentions. Explaining a true intention while under higher cognitive demand places truth tellers at risk of being misclassified. There may be such a thing as too much cognitive load induced by certain techniques.

  2. A reverse order interview does not aid deception detection regarding intentions

    Science.gov (United States)

    Fenn, Elise; McGuire, Mollie; Langben, Sara; Blandón-Gitlin, Iris

    2015-01-01

    Promising recent research suggests that more cognitively demanding interviews improve deception detection accuracy. Would these cognitively demanding techniques work in the same way when discriminating between true and false future intentions? In Experiment 1 participants planned to complete a task, but instead were intercepted and interviewed about their intentions. Participants lied or told the truth, and were subjected to high (reverse order) or low (sequential order) cognitive load interviews. Third-party observers watched these interviews and indicated whether they thought the person was lying or telling the truth. Subjecting participants to a reverse compared to sequential interview increased the misidentification rate and the appearance of cognitive load in truth tellers. People lying about false intentions were not better identified. In Experiment 2, a second set of third-party observers rated behavioral cues. Consistent with Experiment 1, truth tellers, but not liars, exhibited more behaviors associated with lying and fewer behaviors associated with truth telling in the reverse than sequential interview. Together these results suggest that certain cognitively demanding interviews may be less useful when interviewing to detect false intentions. Explaining a true intention while under higher cognitive demand places truth tellers at risk of being misclassified. There may be such a thing as too much cognitive load induced by certain techniques PMID:26379610

  3. Structural transitions in conserved, ordered Beclin 1 domains essential to regulating autophagy

    Energy Technology Data Exchange (ETDEWEB)

    Glover, Karen; Li, Yue; Mukhopadhyay, Shreya; Leuthner, Zoe; Chakravarthy, Srinivas; Colbert, Christopher L.; Sinha, Sangita C. (NDSU); (IIT)

    2017-08-10

    Beclin 1 (BECN1) is a key regulator of autophagy, a critical catabolic homeostasis pathway that involves sequestration of selected cytoplasmic components by multilayered vesicles called autophagosomes, followed by lysosomal fusion and degradation. BECN1 is a core component of class III phosphatidylinositol-3-kinase complexes responsible for autophagosome nucleation. Without heterologous binding partners, BECN1 forms an antiparallel homodimer via its coiled-coil domain (CCD). However, the last 16 CCD residues, composing an “overlap helix” (OH), have been crystallized in two mutually exclusive states: either as part of the CCD or packed against the C-terminal β-α repeated, autophagy-specific domain (BARAD). Here, using CD spectroscopy, isothermal titration calorimetry, and small-angle X-ray scattering, we show that in the homodimeric state, the OH transitions between these two different packing states, with the predominant state comprising the OH packed against the BARAD, contrary to expectations based on known BECN1 interactions with heterologous partners. We confirmed this observation by comparing the impact of mutating four residues that mediate packing of the OH against both the CCD and BARAD on structure and stability of the CCD, the OH+BARAD, and the two-domain CCD–BARAD. Last, we used cellular assays to demonstrate that mutation of these OH-interface residues abrogates starvation-induced up-regulation of autophagy but does not affect basal autophagy. In summary, we have identified a BECN1 helical region that transitions between packing as part of either one of two conserved domains (i.e. the CCD or the BARAD). Our findings have important implications for the relative stability of autophagy-inactive and autophagy-active BECN1 complexes.

  4. Does the order of invasive species removal matter? The case of the eagle and the pig.

    Directory of Open Access Journals (Sweden)

    Paul W Collins

    2009-09-01

    Full Text Available Invasive species are recognized as a primary driver of native species endangerment and their removal is often a key component of a conservation strategy. Removing invasive species is not always a straightforward task, however, especially when they interact with other species in complex ways to negatively influence native species. Because unintended consequences may arise if all invasive species cannot be removed simultaneously, the order of their removal is of paramount importance to ecological restoration. In the mid-1990s, three subspecies of the island fox Urocyon littoralis were driven to near extinction on the northern California Channel Islands owing to heightened predation by golden eagles Aquila chrysaetos. Eagles were lured to the islands by an abundant supply of feral pigs Sus scrofa and through the process of apparent competition pigs indirectly facilitated the decline in foxes. As a consequence, both pigs and eagles had to be removed to recover the critically endangered fox. Complete removal of pigs was problematic: removing pigs first could force eagles to concentrate on the remaining foxes, increasing their probability of extinction. Removing eagles first was difficult: eagles are not easily captured and lethal removal was politically distasteful.Using prey remains collected from eagle nests both before and after the eradication of pigs, we show that one pair of eagles that eluded capture did indeed focus more on foxes. These results support the premise that if the threat of eagle predation had not been mitigated prior to pig removal, fox extinction would have been a more likely outcome.If complete eradication of all interacting invasive species is not possible, the order in which they are removed requires careful consideration. If overlooked, unexpected consequences may result that could impede restoration.

  5. Does the order of invasive species removal matter? The case of the eagle and the pig.

    Science.gov (United States)

    Collins, Paul W; Latta, Brian C; Roemer, Gary W

    2009-09-14

    Invasive species are recognized as a primary driver of native species endangerment and their removal is often a key component of a conservation strategy. Removing invasive species is not always a straightforward task, however, especially when they interact with other species in complex ways to negatively influence native species. Because unintended consequences may arise if all invasive species cannot be removed simultaneously, the order of their removal is of paramount importance to ecological restoration. In the mid-1990s, three subspecies of the island fox Urocyon littoralis were driven to near extinction on the northern California Channel Islands owing to heightened predation by golden eagles Aquila chrysaetos. Eagles were lured to the islands by an abundant supply of feral pigs Sus scrofa and through the process of apparent competition pigs indirectly facilitated the decline in foxes. As a consequence, both pigs and eagles had to be removed to recover the critically endangered fox. Complete removal of pigs was problematic: removing pigs first could force eagles to concentrate on the remaining foxes, increasing their probability of extinction. Removing eagles first was difficult: eagles are not easily captured and lethal removal was politically distasteful. Using prey remains collected from eagle nests both before and after the eradication of pigs, we show that one pair of eagles that eluded capture did indeed focus more on foxes. These results support the premise that if the threat of eagle predation had not been mitigated prior to pig removal, fox extinction would have been a more likely outcome. If complete eradication of all interacting invasive species is not possible, the order in which they are removed requires careful consideration. If overlooked, unexpected consequences may result that could impede restoration.

  6. 77 FR 5385 - Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Revision of...

    Science.gov (United States)

    2012-02-03

    ... the ``order.'' The order is effective under the Agricultural Marketing Agreement Act of 1937, as... DEPARTMENT OF AGRICULTURE Agricultural Marketing Service 7 CFR Part 985 [Doc. Nos. AMS-FV-10-0094; FV11-985-1A FIR] Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West...

  7. 78 FR 23673 - Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Revision of...

    Science.gov (United States)

    2013-04-22

    ... the ``order.'' The order is effective under the Agricultural Marketing Agreement Act of 1937, as... DEPARTMENT OF AGRICULTURE Agricultural Marketing Service 7 CFR Part 985 [Doc. Nos. AMS-FV-11-0088; FV12-985-1A FIR] Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West...

  8. 75 FR 55292 - Amendment to Egg Research and Promotion Order and Regulations To Increase the Rate of Assessment...

    Science.gov (United States)

    2010-09-10

    ...] Amendment to Egg Research and Promotion Order and Regulations To Increase the Rate of Assessment and.... SUMMARY: This proposed rule would amend the Egg Research and Promotion Order (Order) to increase the assessment rate on egg producers paying assessments to the American Egg Board (AEB) from 10 cents to 15 cents...

  9. Assessing preferences about the DNR order: does it depend on how you ask?

    Science.gov (United States)

    Percy, M E; Llewellyn-Thomas, H

    1995-01-01

    Despite increasing emphasis on advance directives, there has been little methodologic work to assess preferences about the "do not resuscitate" (DNR) order. This developmental work assessed, in a non-patient group, the performance of a probability-trade-off task designed to assess DNR attitudes, in terms of framing effects and stability of preferences. 105 female nursing students each completed one of two versions of the task. In version I (n = 58), the trade-off moved to increasingly negative descriptions of the outcomes of resuscitation (decreasing chance of survival and increasing risk of brain death), whereas in version II (n = 47), the trade-off moved to increasingly positive descriptions. One week later, repeat assessments were obtained for versions I (n = 35) and II (n = 28). The DNR preference scores were lower and more stable when the task moved to increasingly positive descriptions; perhaps this version of the task tends to weaken risk aversion. These results imply that care should be used in applying a probability trade-off task to the assessment of DNR preferences, since artefactual effects could be induced.

  10. Getting in (and out of) the loop: regulating higher order telomere structures.

    Science.gov (United States)

    Luke-Glaser, Sarah; Poschke, Heiko; Luke, Brian

    2012-01-01

    The DNA at the ends of linear chromosomes (the telomere) folds back onto itself and forms an intramolecular lariat-like structure. Although the telomere loop has been implicated in the protection of chromosome ends from nuclease-mediated resection and unscheduled DNA repair activities, it potentially poses an obstacle to the DNA replication machinery during S-phase. Therefore, the coordinated regulation of telomere loop formation, maintenance, and resolution is required in order to establish a balance between protecting the chromosome ends and promoting their duplication prior to cell division. Until recently, the only factor known to influence telomere looping in human cells was TRF2, a component of the shelterin complex. Recent work in yeast and mouse cells has uncovered additional regulatory factors that affect the loop structure at telomeres. In the following "perspective" we outline what is known about telomere looping and highlight the latest results regarding the regulation of this chromosome end structure. We speculate about how the manipulation of the telomere loop may have therapeutic implications in terms of diseases associated with telomere dysfunction and uncontrolled proliferation.

  11. Getting in (and out of the loop: regulating higher order telomere structures

    Directory of Open Access Journals (Sweden)

    Sarah eLuke-Glaser

    2012-11-01

    Full Text Available The DNA at the ends of linear chromosomes (the telomere folds back onto itself and forms an intramolecular lariat-like structure. Although the telomere loop has been implicated in the protection of chromosome ends from nuclease-mediated resection and unscheduled DNA repair activities, it potentially poses an obstacle to the DNA replication machinery during S phase. Therefore, the coordinated regulation of telomere loop formation, maintenance and resolution is required in order to establish a balance between protecting the chromosome ends and promoting their duplication prior to cell division. Until recently, the only factor know to influence telomere looping in human cells was TRF2, a component of the shelterin complex. Recent work in yeast and mouse cells has uncovered additional regulatory factors that affect the loop structure at telomeres. In the following perspective we will outline what is known about telomere looping and highlight the latest results regarding the regulation of this chromosome end structure. We will speculate about how the manipulation of the telomere loop may have therapeutic implications in terms of diseases associated with telomere dysfunction and uncontrolled proliferation.

  12. Effects of the Ordering of Natural Selection and Population Regulation Mechanisms on Wright-Fisher Models.

    Science.gov (United States)

    He, Zhangyi; Beaumont, Mark; Yu, Feng

    2017-07-05

    We explore the effect of different mechanisms of natural selection on the evolution of populations for one- and two-locus systems. We compare the effect of viability and fecundity selection in the context of the Wright-Fisher model with selection under the assumption of multiplicative fitness. We show that these two modes of natural selection correspond to different orderings of the processes of population regulation and natural selection in the Wright-Fisher model. We find that under the Wright-Fisher model these two different orderings can affect the distribution of trajectories of haplotype frequencies evolving with genetic recombination. However, the difference in the distribution of trajectories is only appreciable when the population is in significant linkage disequilibrium. We find that as linkage disequilibrium decays the trajectories for the two different models rapidly become indistinguishable. We discuss the significance of these findings in terms of biological examples of viability and fecundity selection, and speculate that the effect may be significant when factors such as gene migration maintain a degree of linkage disequilibrium. Copyright © 2017 He et al.

  13. Does enhanced regulation improve EIA report quality? Lessons from South Africa

    Energy Technology Data Exchange (ETDEWEB)

    Sandham, L.A., E-mail: luke.sandham@nwu.ac.za [Environmental Assessment Research Group, School of Geo and Spatial Sciences, North-West University, Private Bag X6001, Potchefstroom, 2520 (South Africa); Heerden, A.J. van [Environmental Assessment Research Group, School of Geo and Spatial Sciences, North-West University, Private Bag X6001, Potchefstroom, 2520 (South Africa); Jones, C.E. [School of Environment and Development, University of Manchester, Oxford Road, Manchester, M13 9PL (United Kingdom); Retief, F.P.; Morrison-Saunders, A.N. [Environmental Assessment Research Group, School of Geo and Spatial Sciences, North-West University, Private Bag X6001, Potchefstroom, 2520 (South Africa)

    2013-01-15

    Recently, various EIA systems have been subjected to system review processes with a view to improve performance. Many of these reviews resulted in some form of legislative reform. The South African Environmental Impact Assessment (EIA) regulations were modified in 2006 with the express intent to improve EIA effectiveness. In order to evaluate to what extent the desired outcome was achieved, the quality of EIA reports produced under the 2006 regulations was investigated for comparative analysis with the preceding regime. A sample of EIA reports from the two legislative regimes was reviewed using an adapted version of a well established method known colloquially as the 'Lee and Colley' review package. Despite some improvements in certain aspects, overall report quality has decreased slightly from the 1997 EIA regime. It therefore appears that the modifications to the regulations, often heralded as the solution to improvements in performance have not resulted in improved quality of EIA reports. - Highlights: Black-Right-Pointing-Pointer EIA regulations in South Africa were revised and became more comprehensive in 2006. Black-Right-Pointing-Pointer The report quality of a sample of EIAs was reviewed using the Lee and Colley review package. Black-Right-Pointing-Pointer Report quality showed a slight decline from the previous regulatory regime. Black-Right-Pointing-Pointer EIA good practice needs flexibility rather than over-detailed regulation.

  14. Does enhanced regulation improve EIA report quality? Lessons from South Africa

    International Nuclear Information System (INIS)

    Sandham, L.A.; Heerden, A.J. van; Jones, C.E.; Retief, F.P.; Morrison-Saunders, A.N.

    2013-01-01

    Recently, various EIA systems have been subjected to system review processes with a view to improve performance. Many of these reviews resulted in some form of legislative reform. The South African Environmental Impact Assessment (EIA) regulations were modified in 2006 with the express intent to improve EIA effectiveness. In order to evaluate to what extent the desired outcome was achieved, the quality of EIA reports produced under the 2006 regulations was investigated for comparative analysis with the preceding regime. A sample of EIA reports from the two legislative regimes was reviewed using an adapted version of a well established method known colloquially as the “Lee and Colley” review package. Despite some improvements in certain aspects, overall report quality has decreased slightly from the 1997 EIA regime. It therefore appears that the modifications to the regulations, often heralded as the solution to improvements in performance have not resulted in improved quality of EIA reports. - Highlights: ► EIA regulations in South Africa were revised and became more comprehensive in 2006. ► The report quality of a sample of EIAs was reviewed using the Lee and Colley review package. ► Report quality showed a slight decline from the previous regulatory regime. ► EIA good practice needs flexibility rather than over-detailed regulation.

  15. How does the tobacco industry attempt to influence marketing regulations? A systematic review.

    Directory of Open Access Journals (Sweden)

    Emily Savell

    Full Text Available The Framework Convention on Tobacco Control makes a number of recommendations aimed at restricting the marketing of tobacco products. Tobacco industry political activity has been identified as an obstacle to Parties' development and implementation of these provisions. This study systematically reviews the existing literature on tobacco industry efforts to influence marketing regulations and develops taxonomies of 1 industry strategies and tactics and 2 industry frames and arguments.Searches were conducted between April-July 2011, and updated in March 2013. Articles were included if they made reference to tobacco industry efforts to influence marketing regulations; supported claims with verifiable evidence; were written in English; and concerned the period 1990-2013. 48 articles met the review criteria. Narrative synthesis was used to combine the evidence.56% of articles focused on activity in North America, Europe or Australasia, the rest focusing on Asia (17%, South America, Africa or transnational activity. Six main political strategies and four main frames were identified. The tobacco industry frequently claims that the proposed policy will have negative unintended consequences, that there are legal barriers to regulation, and that the regulation is unnecessary because, for example, industry does not market to youth or adheres to a voluntary code. The industry primarily conveys these arguments through direct and indirect lobbying, the promotion of voluntary codes and alternative policies, and the formation of alliances with other industrial sectors. The majority of tactics and arguments were used in multiple jurisdictions.Tobacco industry political activity is far more diverse than suggested by existing taxonomies of corporate political activity. Tactics and arguments are repeated across jurisdictions, suggesting that the taxonomies of industry tactics and arguments developed in this paper are generalisable to multiple jurisdictions and can

  16. 25 CFR 518.8 - Does a tribe that holds a certificate of self-regulation have a continuing duty to advise the...

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Does a tribe that holds a certificate of self-regulation... NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS SELF REGULATION OF CLASS II GAMING § 518.8 Does a tribe that holds a certificate of self-regulation have a continuing duty to...

  17. Does Training in How to Regulate One's Learning Affect How Students Report Self-Regulated Learning in Diary Tasks?

    Science.gov (United States)

    Costa Ferreira, P.; Veiga Simão, A. M.; Lopes da Silva, A.

    2015-01-01

    The processes and perceptions of students' self-regulated learning are not easily measured. Thus, research has presented and suggested numerous ways in which these processes and perceptions of self-regulated learning can be investigated and assessed. Accordingly, this study aims to assess whether training in how to regulate one's learning is…

  18. 77 FR 51957 - Defense Federal Acquisition Regulation Supplement: Clarification of “F” Orders in the Procurement...

    Science.gov (United States)

    2012-08-28

    ... multi-agency contracts, or basic ordering agreements. The proposed text also directs that a... agreements, or blanket purchase agreements. As a result of the proposed rule, new awards under the AbilityOne... Part 204 Government procurement. Manuel Quinones, Editor, Defense Acquisition Regulations System...

  19. 77 FR 13019 - Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Salable...

    Science.gov (United States)

    2012-03-05

    ... DEPARTMENT OF AGRICULTURE Agricultural Marketing Service 7 CFR Part 985 [Doc. No. AMS-FV-11-0088; FV12-985-1 PR] Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Salable Quantities and Allotment Percentages for the 2012-2013 Marketing Year AGENCY: Agricultural...

  20. 78 FR 32070 - Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Salable...

    Science.gov (United States)

    2013-05-29

    ... DEPARTMENT OF AGRICULTURE Agricultural Marketing Service 7 CFR Part 985 [Doc. No. AMS-FV-12-0064; FV13-985-1 FR] Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Salable Quantities and Allotment Percentages for the 2013-2014 Marketing Year AGENCY: Agricultural...

  1. 76 FR 27852 - Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Salable...

    Science.gov (United States)

    2011-05-13

    ... DEPARTMENT OF AGRICULTURE Agricultural Marketing Service 7 CFR Part 985 [Doc. No. AMS-FV-10-0094; FV11-985-1 FR] Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Salable Quantities and Allotment Percentages for the 2011-2012 Marketing Year AGENCY: Agricultural...

  2. 76 FR 61933 - Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Revision of...

    Science.gov (United States)

    2011-10-06

    ..., 733,877 pounds of Scotch spearmint oil have already been sold or committed, which leaves just 186,505... of essential oils and the products of essential oils. In addition, the Committee estimates that 8 of...-1A IR] Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Revision of...

  3. 78 FR 9575 - Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Change to...

    Science.gov (United States)

    2013-02-11

    ... reserve oil in such manner as to accurately account for its receipt, storage, and disposition. In a rule... FR] Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Change to Administrative Rules Regarding the Transfer and Storage of Excess Spearmint Oil AGENCY: Agricultural Marketing...

  4. 77 FR 57037 - Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Change to...

    Science.gov (United States)

    2012-09-17

    ... Service 7 CFR Part 985 [Doc. No. AMS-FV-12-0014; FV12-985-2 PR] Marketing Order Regulating the Handling of... Excess Spearmint Oil AGENCY: Agricultural Marketing Service, USDA. ACTION: Proposed rule. SUMMARY: This... Act (RFA), the Agricultural Marketing Service (AMS) has considered the economic impact of this action...

  5. 75 FR 60690 - Defense Federal Acquisition Regulation Supplement (DFARS); Electronic Ordering Procedures (DFARS...

    Science.gov (United States)

    2010-10-01

    ... event of conflict between a delivery order or task order and this contract, the contract shall control.... This change will ultimately help improve the management and promotion of electronic Government services... impose any information collection requirements that require the approval of the Office of Management and...

  6. 75 FR 48276 - Defense Federal Acquisition Regulation Supplement; Management of Unpriced Change Orders

    Science.gov (United States)

    2010-08-10

    ... to make requirements for DoD management and oversight of unpriced change orders consistent with those... management and oversight of undefinitized contract actions (UCAs). In the current DFARS, unpriced change... procedures. The rule makes requirements for DoD management and oversight of unpriced change orders consistent...

  7. Exercise training during normobaric hypoxic confinement does not alter hormonal appetite regulation.

    Directory of Open Access Journals (Sweden)

    Tadej Debevec

    Full Text Available Both exposure to hypoxia and exercise training have the potential to modulate appetite and induce beneficial metabolic adaptations. The purpose of this study was to determine whether daily moderate exercise training performed during a 10-day exposure to normobaric hypoxia alters hormonal appetite regulation and augments metabolic health.Fourteen healthy, male participants underwent a 10-day hypoxic confinement at ∼ 4000 m simulated altitude (FIO2 = 0.139 ± 0.003% either combined with daily moderate intensity exercise (Exercise group; N = 8, Age = 25.8 ± 2.4 yrs, BMI = 22.9 ± 1.2 kg · m(-2 or without any exercise (Sedentary group; N = 6 Age = 24.8 ± 3.1 yrs, BMI = 22.3 ± 2.5 kg · m(-2. A meal tolerance test was performed before (Pre and after the confinement (Post to quantify fasting and postp randial concentrations of selected appetite-related hormones and metabolic risk markers. 13C-Glucose was dissolved in the test meal and 13CO2 determined in breath samples. Perceived appetite ratings were obtained throughout the meal tolerance tests.While body mass decreased in both groups (-1.4 kg; p = 0.01 following the confinement, whole body fat mass was only reduced in the Exercise group (-1.5 kg; p = 0.01. At Post, postprandial serum insulin was reduced in the Sedentary group (-49%; p = 0.01 and postprandial plasma glucose in the Exercise group (-19%; p = 0.03. Fasting serum total cholesterol levels were reduced (-12%; p = 0.01 at Post in the Exercise group only, secondary to low-density lipoprotein cholesterol reduction (-16%; p = 0.01. No differences between groups or testing periods were noted in fasting and/or postprandial concentrations of total ghrelin, peptide YY, and glucagon-like peptide-1, leptin, adiponectin, expired 13CO2 as well as perceived appetite ratings (p>0.05.These findings suggest that performing daily moderate intensity exercise training during continuous hypoxic exposure does not alter hormonal appetite regulation but

  8. Exercise training during normobaric hypoxic confinement does not alter hormonal appetite regulation.

    Science.gov (United States)

    Debevec, Tadej; Simpson, Elizabeth J; Macdonald, Ian A; Eiken, Ola; Mekjavic, Igor B

    2014-01-01

    Both exposure to hypoxia and exercise training have the potential to modulate appetite and induce beneficial metabolic adaptations. The purpose of this study was to determine whether daily moderate exercise training performed during a 10-day exposure to normobaric hypoxia alters hormonal appetite regulation and augments metabolic health. Fourteen healthy, male participants underwent a 10-day hypoxic confinement at ∼ 4000 m simulated altitude (FIO2 = 0.139 ± 0.003%) either combined with daily moderate intensity exercise (Exercise group; N = 8, Age = 25.8 ± 2.4 yrs, BMI = 22.9 ± 1.2 kg · m(-2)) or without any exercise (Sedentary group; N = 6 Age = 24.8 ± 3.1 yrs, BMI = 22.3 ± 2.5 kg · m(-2)). A meal tolerance test was performed before (Pre) and after the confinement (Post) to quantify fasting and postp randial concentrations of selected appetite-related hormones and metabolic risk markers. 13C-Glucose was dissolved in the test meal and 13CO2 determined in breath samples. Perceived appetite ratings were obtained throughout the meal tolerance tests. While body mass decreased in both groups (-1.4 kg; p = 0.01) following the confinement, whole body fat mass was only reduced in the Exercise group (-1.5 kg; p = 0.01). At Post, postprandial serum insulin was reduced in the Sedentary group (-49%; p = 0.01) and postprandial plasma glucose in the Exercise group (-19%; p = 0.03). Fasting serum total cholesterol levels were reduced (-12%; p = 0.01) at Post in the Exercise group only, secondary to low-density lipoprotein cholesterol reduction (-16%; p = 0.01). No differences between groups or testing periods were noted in fasting and/or postprandial concentrations of total ghrelin, peptide YY, and glucagon-like peptide-1, leptin, adiponectin, expired 13CO2 as well as perceived appetite ratings (p>0.05). These findings suggest that performing daily moderate intensity exercise training during continuous hypoxic exposure does not alter hormonal appetite regulation but can

  9. 76 FR 61289 - Public Hearing on Child Labor Regulations, Orders and Statements of Interpretation; Child Labor...

    Science.gov (United States)

    2011-10-04

    ... address, telephone number, e-mail addresses and medical data in the submission, the Department urges... working youth that are healthy, safe, and not detrimental to their education. (76 FR 54836). As mentioned... regulation for 14- and 15-year-olds to work in suitable occupations other than manufacturing or mining, and...

  10. 78 FR 43785 - Exemptive Order Regarding Compliance With Certain Swap Regulations

    Science.gov (United States)

    2013-07-22

    .... bank that is an SD or MSP, and which is located in Australia, Canada, the European Union, Hong Kong... Derivatives Supervisors' Group (``ODSG''), the Federal Reserve Bank of New York led an effort along with the... Commission's regulations.\\1\\ \\1\\ See 17 CFR 145.9. The Commission reserves the right, but shall have no...

  11. 76 FR 25566 - Defense Federal Acquisition Regulation Supplement (DFARS); Electronic Ordering Procedures (DFARS...

    Science.gov (United States)

    2011-05-05

    ... officials to specify e-mail as an ``electronic commerce method'' so long as it is authorized in the schedule... recognized electronic commerce method. The respondent recommended, in the alternative, that the Government... stated that electronic commerce is a term specifically identified in Federal Acquisition Regulation (FAR...

  12. 75 FR 39625 - Elimination of Flash Order Exception From Rule 602 of Regulation NMS

    Science.gov (United States)

    2010-07-09

    ... reduction in access fees, such as through an impact on spreads or order book liquidity? If so, how much..., Professor of Finance and Business Economics, USC Marshall School of Business, dated December 4, 2009...

  13. How Does Environmental Regulation Affect Industrial Transformation? A Study Based on the Methodology of Policy Simulation

    Directory of Open Access Journals (Sweden)

    Wei Liu

    2016-01-01

    Full Text Available The difference of factor input structure determines different response to environmental regulation. This paper constructs a theoretical model including environmental regulation, factor input structure, and industrial transformation and conducts a policy simulation based on the difference of influencing mechanism of environmental regulation considering industrial heterogeneity. The findings show that the impact of environmental regulation on industrial transformation presents comparison of distortion effect of resource allocation and technology effect. Environmental regulation will promote industrial transformation when technology effect of environmental regulation is stronger than distortion effect of resource allocation. Particularly, command-control environmental regulation has a significant incentive effect and spillover effect of technological innovation on cleaning industries, but these effects do not exist in pollution-intensive industries. Command-control environmental regulation promotes industrial transformation. The result of simulation showed that environmental regulation of market incentives is similar to that of command-control.

  14. 1994 annual report on waste generation and waste minimization progress as required by DOE Order 5400.1

    International Nuclear Information System (INIS)

    Irwin, E.F.; Poligone, S.E.

    1995-01-01

    The Y-12 Plant serves as a key manufacturing technology center for the development and demonstration of unique materials, components, and services of importance to the Department of Energy (DOE) and the nation. This is accomplished through the reclamation and storage of nuclear materials, manufacture of nuclear materials, manufacture of components for the nation's defense capabilities, support to national security programs, and services provided to other customers as approved by DOE. We are recognized by our people, the community, and our customers as innovative, responsive, and responsible. We are a leader in worker health and safety, environmental protection, and stewardship of our national resources. As a DOE facility, Y-12 also supports DOE's waste minimization mission. Data contained in this report represents waste generation in Tennessee

  15. Presentation note of the order project related to the general technical regulation applicable to INBs

    International Nuclear Information System (INIS)

    2010-01-01

    This document presents the scope of the order project which defines the main requirements applicable to INBs (base nuclear installations) in terms of protection of people and of the environment in front of risks of accident, of pollutions and other nuisances. More precisely, the document explains the scope of the several specific aspects addressed by this order: safety policy and management, accident risk management, management of nuisance and of the installation impact on population and on the environment, management and elimination of wastes and fuels spent by a base nuclear installation, management of emergency situations, population information, authorization request procedures, and other provisions

  16. How Does Self-Regulation Affect Computer-Programming Achievement in a Blended Context?

    Science.gov (United States)

    Cigdem, Harun

    2015-01-01

    This study focuses on learners' self-regulation which is one of the essential skills for student achievement in blended courses. Research on learners' self-regulation skills in blended learning environments has gained popularity in recent years however only a few studies investigating the correlation between self-regulation skills and student…

  17. The Legal Structure of Commercial Banks and Financial Regulation : does organizational form matter for the design of bank regulation?

    NARCIS (Netherlands)

    V.L.E. Cedeno-Brea (Enmanuel)

    2017-01-01

    markdownabstractDo the different ways that commercial banks are legally organized matter for the design of financial regulation? It is often assumed that most commercial banks are setup as investor owned business corporations. However, this is not always the case In many jurisdictions, banks are

  18. Royal Order of 18 May 1971 regulating Ministerial competences in atomic energy

    International Nuclear Information System (INIS)

    1971-01-01

    This Order suppresses the office of Commissioner for Atomic Energy and lays down that questions relating to the peaceful use of atomic energy and to nuclear research centres fall within the competence of the Minister for Economic Affairs. The Prime Minister, responsible for co-ordinating scientific policy, is competent for the organization and programming of nuclear research activities financed by the State. (NEA) [fr

  19. The Legal Structure of Commercial Banks and Financial Regulation : does organizational form matter for the design of bank regulation?

    OpenAIRE

    Cedeno-Brea, Enmanuel

    2017-01-01

    markdownabstractDo the different ways that commercial banks are legally organized matter for the design of financial regulation? It is often assumed that most commercial banks are setup as investor owned business corporations. However, this is not always the case In many jurisdictions, banks are legally organized using a plethora of organizational forms, which include: co-operatives, mutual associations and even nonprofit entities. Thus, some of the distinctive legal attributes and features o...

  20. The Fat-Dachsous signaling pathway regulates growth of horns in Trypoxylus dichotomus, but does not affect horn allometry.

    Science.gov (United States)

    Hust, James; Lavine, Mark D; Worthington, Amy M; Zinna, Robert; Gotoh, Hiroki; Niimi, T; Lavine, Laura

    Males of the Asian rhinoceros beetle, Trypoxylus dichotomus, possess exaggerated head and thoracic horns that scale dramatically out of proportion to body size. While studies of insulin signaling suggest that this pathway regulates nutrition-dependent growth including exaggerated horns, what regulates disproportionate growth has yet to be identified. The Fat signaling pathway is a potential candidate for regulating disproportionate growth of sexually-selected traits, a hypothesis we advanced in a previous paper (Gotoh et al., 2015). To investigate the role of Fat signaling in the growth and scaling of the sexually dimorphic, condition-dependent traits of the in the Asian rhinoceros beetle T. dichotomus, we used RNA interference to knock down expression of fat and its co-receptor dachsous. Knockdown of fat, and to a lesser degree dachsous, caused shortening and widening of appendages, including the head and thoracic horns. However, scaling of horns to body size was not affected. Our results show that Fat signaling regulates horn growth in T. dichotomus as it does in appendage growth in other insects. However, we provide evidence that Fat signaling does not mediate the disproportionate, positive allometric growth of horns in T. dichotomus. Copyright © 2018 Elsevier Ltd. All rights reserved.

  1. Does Emotion Regulation Change in Treatment? An Investigation of cognitive-oriented therapies.

    OpenAIRE

    Finsrud, Ingvild

    2016-01-01

    Objective: Recently, there has been increased interest in the study of emotion regulation difficulties in psychopathology. Anxiety disorders are among the most common mental illnesses, and growing research suggests that emotion regulation difficulties function as a maintaining factor in these disorders. A common characteristic of the various types of anxiety disorders is the use of inhibited emotion regulation strategies such as worry, suppression, and avoidance. Hence, our understanding of t...

  2. 10 CFR 603.125 - Applicability of other parts of the DOE Assistance Regulations.

    Science.gov (United States)

    2010-01-01

    ... Regulations. 603.125 Section 603.125 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY...: (1) 10 CFR part 601—lobbying restrictions apply by law (31 U.S.C. 1352) to a TIA that is a... nonprocurement instruments in general; and (3) 10 CFR part 607—drug-free work-place (financial assistance...

  3. Considerations for State Regulators and Policymakers in a Post-FERC Order 745 World

    Energy Technology Data Exchange (ETDEWEB)

    Cappers, Peter [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Satchwell, Andy [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-02-01

    By vacating the Federal Energy Commission's (FERC) Order 745 in Electric Power Supply Association vs. FERC (EPSA, 2014) the U.S. Court of Appeals for the D.C Circuit injected uncertainty into the future of demand response (DR) resources in U.S. wholesale markets. Many possible future scenarios in which DR continues to be available to provide capacity for resource adequacy would need to rely on a potential checkerboard of policies promulgated by state utility commissions. However, the states that will be most directly impacted by the potential implications from the EPSA ruling are precisely those that have the fewest policies currently in place to promote retail program development.

  4. Supporting the self-regulatory resource: does conscious self-regulation incidentally prime nonconscious support processes?

    Science.gov (United States)

    Dorris, Derek C

    2009-11-01

    Ego-depletion (depletion of self-regulatory strength) can impair conscious efforts at self-regulation. Research into nonconscious self-regulation has demonstrated that preconscious automaticity and implementation intentions can automatically carry out regulatory tasks during times of ego-depletion. However, preconscious automaticity can only emerge during well-practiced tasks while implementation intentions can only support tasks that have been explicitly planned. Thus, when it comes to supporting the conscious self-regulation of nonroutine and unplanned behaviour during times of ego-depletion these processes should be ineffective. However, it is argued here that because the conscious self-regulation of nonroutine and unplanned behaviour can incidentally prime the underlying mental representations those primed representations can be postconsciously re-activated to support that behaviour during times of ego-depletion. Postconscious self-regulation might, therefore, support a type of self-regulatory behaviour that has, thus far, not been associated with any form of support.

  5. Does Preschool Self-Regulation Predict Later Behavior Problems in General or Specific Problem Behaviors?

    Science.gov (United States)

    Lonigan, Christopher J; Spiegel, Jamie A; Goodrich, J Marc; Morris, Brittany M; Osborne, Colleen M; Lerner, Matthew D; Phillips, Beth M

    2017-11-01

    Findings from prior research have consistently indicated significant associations between self-regulation and externalizing behaviors. Significant associations have also been reported between children's language skills and both externalizing behaviors and self-regulation. Few studies to date, however, have examined these relations longitudinally, simultaneously, or with respect to unique clusters of externalizing problems. The current study examined the influence of preschool self-regulation on general and specific externalizing behavior problems in early elementary school and whether these relations were independent of associations between language, self-regulation, and externalizing behaviors in a sample of 815 children (44% female). Additionally, given a general pattern of sex differences in the presentations of externalizing behavior problems, self-regulation, and language skills, sex differences for these associations were examined. Results indicated unique relations of preschool self-regulation and language with both general externalizing behavior problems and specific problems of inattention. In general, self-regulation was a stronger longitudinal correlate of externalizing behavior for boys than it was for girls, and language was a stronger longitudinal predictor of hyperactive/impulsive behavior for girls than it was for boys.

  6. Order for execution of the law concerning regulations of nuclear source materials, nuclear fuel materials and reactors

    International Nuclear Information System (INIS)

    1981-01-01

    This ordinance is stipulated under the law concerning the regulation of nuclear raw materials, nuclear fuel materials and reactors. The designation for refining and processing businesses under the law shall be obtained for each works or enterprise where these operations are to be practiced. Persons who intend to accept the designation shall file applications attaching business plans and the other documents specified by the ordinances of the Prime Minister's Office and other ministry orders. The permission for the installation of nuclear reactors under the law shall be received for each works or enterprise where reactors are to be set up. Persons who intend to get the permission shall file applications attaching the financing plans required for the installation of reactors and the other documents designated by the orders of the competent ministry. The permission concerning the reactors installed on foreign ships shall be obtained for each ship which is going to enter into the Japanese waters. Persons who ask for the permission shall file applications attaching the documents which explain the safety of reactor facilities and the other documents defined by the orders of the Ministry of Transportation. The designation for reprocessing business and the application for it are provided for, respectively. The usage of nuclear fuel materials, nuclear raw materials and internationally regulated goods is ruled in detail.(Okada, K.)

  7. Order for execution of the law concerning regulations of nuclear source materials, nuclear fuel materials and reactors

    International Nuclear Information System (INIS)

    1985-01-01

    This ordinance is stipulated under the law concerning the regulation of nuclear raw materials, nuclear fuel materials and reactors. The designation for refining and processing businesses under the law shall be obtained for each works or enterprise where these operations are to be practiced. Persons who intend to accept the designation shall file applications attaching business plans and the other documents specified by the ordinances of the Prime Minister's Office and other ministry orders. The permission for the installation of nuclear reactors under the law shall be received for each works or enterprise where reactors are to be set up. Persons who intend to get the permission shall file applications attaching the financing plans required for the installation of reactors and the other documents designated by the orders of the competent ministry. The permission concerning the reactors installed on foreign ships shall be obtained for each ship which is going to enter into the Japanese waters. Persons who ask for the permission shall file applications attaching the documents which explain the safety of reactor facilities and the other documents defined by the orders of the Ministry of Transportation. The designation for reprocessing business and the application for it are provided for, respectively. The usage of nuclear fuel materials, nuclear raw materials and internationally regulated goods is ruled in detail. (Kubozone, M.)

  8. Bank regulation and financial fragility in developing countries: Does bank structure matter?

    Directory of Open Access Journals (Sweden)

    Jeroen Klomp

    2015-12-01

    Full Text Available Using data for 1238 banks located in 94 developing and emerging countries, we explore whether the impact of bank regulation and supervision on banking risk (measured by the banks’ Z-scores depends on bank structure. Our findings suggest that stricter regulation and supervision increases the banks’ Z-scores. Notably capital requirements and supervisory control diminish banking risk. However, the effectiveness of other dimensions of regulation and supervision depends on the organizational structure of banks. Notably activity restrictions reduce risk of large and foreign owned banks, while liquidity restrictions have most effect on the Z-scores of unlisted and commercial banks.

  9. One size does not fit all: On how Markov model order dictates performance of genomic sequence analyses

    Science.gov (United States)

    Narlikar, Leelavati; Mehta, Nidhi; Galande, Sanjeev; Arjunwadkar, Mihir

    2013-01-01

    The structural simplicity and ability to capture serial correlations make Markov models a popular modeling choice in several genomic analyses, such as identification of motifs, genes and regulatory elements. A critical, yet relatively unexplored, issue is the determination of the order of the Markov model. Most biological applications use a predetermined order for all data sets indiscriminately. Here, we show the vast variation in the performance of such applications with the order. To identify the ‘optimal’ order, we investigated two model selection criteria: Akaike information criterion and Bayesian information criterion (BIC). The BIC optimal order delivers the best performance for mammalian phylogeny reconstruction and motif discovery. Importantly, this order is different from orders typically used by many tools, suggesting that a simple additional step determining this order can significantly improve results. Further, we describe a novel classification approach based on BIC optimal Markov models to predict functionality of tissue-specific promoters. Our classifier discriminates between promoters active across 12 different tissues with remarkable accuracy, yielding 3 times the precision expected by chance. Application to the metagenomics problem of identifying the taxum from a short DNA fragment yields accuracies at least as high as the more complex mainstream methodologies, while retaining conceptual and computational simplicity. PMID:23267010

  10. Does It Help to Use Mathematically Superfluous Brackets When Teaching the Rules for the Order of Operations?

    Science.gov (United States)

    Gunnarsson, Robert; Sönnerhed, Wang Wei; Hernell, Bernt

    2016-01-01

    The hypothesis that mathematically superfluous brackets can be useful when teaching the rules for the order of operations is challenged. The idea of the hypothesis is that with brackets it is possible to emphasize the order priority of one operation over another. An experiment was conducted where expressions with mixed operations were studied,…

  11. Influence of Rabbit Sire Genetic Origin, Season of Birth and Parity Order on Doe and Litter Performance in an Organic Production System

    Directory of Open Access Journals (Sweden)

    Antonella Dalle Zotte

    2013-01-01

    Full Text Available The aim of this study was to compare both the performance of litters derived from two sire genetic origins (SGO, Vienna Blue (VB and Burgundy Fawn (BF, along successive seasons of birth (SB; winter, spring, summer and autumn, and doe reproductive performance in an organic production system. A total of fifty-eight does consisting of a mixture of crosses of several medium-large size breeds at different parity order (P, 1 = nulliparous; 2 = primiparous; ≥3 = multiparous and twelve males (6 VB and 6 BF were housed indoors at environmental conditions that followed seasonality. An extensive reproductive rhythm was used and kits were weaned at 46±6 d of age. Doe reproductive performance and the data of 105 litters (55 from VB and 50 from BF SGO were recorded throughout the SB. No statistically significant differences related to SGO effect were observed. As regards parity order, multiparous does showed higher live weights (LW (p<0.05, total born (p<0.01, total born alive (p<0.05 per delivery, and litter weight of born alive (p<0.05, but lower milk output at 21st d than primiparous does (p<0.05. The extensive reproductive rhythm mainly increased litter performance at birth in multiparous does but was not sufficient to permit a complete recovery of body reserves lost during lactation. Autumn SB negatively affected doe LW variation between deliveries. The number of pups born and born alive per delivery (p<0.05 and litter size at 21 d of age and at weaning (p<0.01 were lower during hot SB. Due to the lower litter size of pups born in summer and autumn, their individual weight at 21st d of age and daily individual growth rate 0 to 21 d were higher than those of pups born in winter (p<0.001. Litter performance at 21st d of age and individual pup pre-weaning growth rate were poorer for those born in spring than in other seasons due to the harmful effects of increased environmental temperatures. SB affected most of the performance traits of does and young

  12. Small Area Estimate Maps: Does the FDA Regulate Tobacco? - Small Area Estimates

    Science.gov (United States)

    This metric is defined as a person 18 years of age or older who must have reported that he/she believes that the United States Food and Drug Administration (FDA) regulates tobacco products in the U.S.

  13. Emotion regulation as the foundation of political attitudes: does reappraisal decrease support for conservative policies?

    Directory of Open Access Journals (Sweden)

    Jooa Julia Lee

    Full Text Available Cognitive scientists, behavior geneticists, and political scientists have identified several ways in which emotions influence political attitudes, and psychologists have shown that emotion regulation can have an important causal effect on physiology, cognition, and subjective experience. However, no work to date explores the possibility that emotion regulation may shape political ideology and attitudes toward policies. Here, we conduct four studies that investigate the role of a particular emotion regulation strategy--reappraisal in particular. Two observational studies show that individual differences in emotion regulation styles predict variation in political orientations and support for conservative policies. In the third study, we experimentally induce disgust as the target emotion to be regulated and show that use of reappraisal reduces the experience of disgust, thereby decreasing moral concerns associated with conservatism. In the final experimental study, we show that use of reappraisal successfully attenuates the relationship between trait-level disgust sensitivity and support for conservative policies. Our findings provide the first evidence of a critical link between emotion regulation and political attitudes.

  14. Emotion Regulation as the Foundation of Political Attitudes: Does Reappraisal Decrease Support for Conservative Policies?

    Science.gov (United States)

    Lee, Jooa Julia; Sohn, Yunkyu; Fowler, James H.

    2013-01-01

    Cognitive scientists, behavior geneticists, and political scientists have identified several ways in which emotions influence political attitudes, and psychologists have shown that emotion regulation can have an important causal effect on physiology, cognition, and subjective experience. However, no work to date explores the possibility that emotion regulation may shape political ideology and attitudes toward policies. Here, we conduct four studies that investigate the role of a particular emotion regulation strategy – reappraisal in particular. Two observational studies show that individual differences in emotion regulation styles predict variation in political orientations and support for conservative policies. In the third study, we experimentally induce disgust as the target emotion to be regulated and show that use of reappraisal reduces the experience of disgust, thereby decreasing moral concerns associated with conservatism. In the final experimental study, we show that use of reappraisal successfully attenuates the relationship between trait-level disgust sensitivity and support for conservative policies. Our findings provide the first evidence of a critical link between emotion regulation and political attitudes. PMID:24367583

  15. Social Regulation of Learning During Collaborative Inquiry Learning in Science: How does it emerge and what are its functions?

    Science.gov (United States)

    Ucan, Serkan; Webb, Mary

    2015-10-01

    Students' ability to regulate their learning is considered important for the quality of collaborative inquiry learning. However, there is still limited understanding about how students engage in social forms of regulation processes and what roles these regulatory processes may play during collaborative learning. The purpose of this study was to identify when and how co- and shared regulation of metacognitive, emotional and motivational processes emerge and function during collaborative inquiry learning in science. Two groups of three students (aged 12) from a private primary school in Turkey were videotaped during collaborative inquiry activities in a naturalistic classroom setting over a seven-week period, and the transcripts were analysed in order to identify their use of regulation processes. Moreover, this was combined with the analysis of stimulated-recall interviews with the student groups. Results indicated that co- and shared regulation processes were often initiated by particular events and played a crucial role in the success of students' collaborative inquiry learning. Co-regulation of metacognitive processes had the function of stimulating students to reflect upon and clarify their thinking, as well as facilitating the construction of new scientific understanding. Shared regulation of metacognitive processes helped students to build a shared understanding of the task, clarify and justify their shared perspective, and sustain the ongoing knowledge co-construction. Moreover, the use of shared emotional and motivational regulation was identified as important for sustaining reciprocal interactions and creating a positive socio-emotional atmosphere within the groups. In addition, the findings revealed links between the positive quality of group interactions and the emergence of co- and shared regulation of metacognitive processes. This study highlights the importance of fostering students' acquisition and use of regulation processes during collaborative

  16. DOE ORDER 435.1, IMPLEMENTATION AND COMPLIANCE DECLARATION AT THE SAVANNAH RIVER SITE AND ACROSS THE DOE COMPLEX IN CONTRAST TO CURRENT PUSHBACK EFFORTS FROM THE ''TOP-TO-BOTTOM'' REVIEW

    International Nuclear Information System (INIS)

    GOLDSTON, WELFORD T.; SMITH, WINCHESTER IV.

    2003-01-01

    DOE issued Order 435.1, ''Radioactive Waste Management,'' on July 9, 1999 for immediate implementation. The requirements for Low Level Mixed, Transuranic, and High Level Waste have been completely rewritten. The entire DOE complex has been struggling with how to implement these new requirements within the one year required timeframe. This paper will chronicle the implementation strategy and actual results of the work to carry out that strategy at the Savannah River Site. DOE-SR and the site contractors worked closely together to implement each of the new requirements across the SRS, crossing many barriers and providing innovative solutions to the many problems that surfaced throughout the year. The results are that SRS declared compliance with all of the requirements of the Order within the prescribed timeframe. The challenge included all waste types in SRS facilities and programs that handle LLW, MLLW, TRU, and HLW. This paper will describe the implementation details for development of Radioactive Waste Management Basis for each facility, Identification of Wastes with No Path to Disposal, Waste Incidental to Reprocessing Determinations, Low Level Waste 90-Day Staging and One Year Limits for Storage Programs, to name a few of the requirements that were addressed by the SRS 435.1 Implementation Team. This paper will trace the implementation, problems (both technical and administrative), and the current pushback efforts associated with the DOE ''Top-to-Bottom'' review

  17. How does the alcohol industry attempt to influence marketing regulations? A systematic review

    Science.gov (United States)

    Fooks, Gary; Gilmore, Anna B.

    2016-01-01

    Abstract Aim To systematically review, using a qualitative, narrative synthesis approach, papers examining alcohol industry efforts to influence alcohol marketing policy, and compare with those used by the tobacco industry. Methods Literature searches were conducted between April and July 2011, and updated in March 2013. Papers were included if they: made reference to alcohol industry efforts to influence (a) policy debates concerning marketing regulations, (b) new specific marketing policies or (c) broad alcohol policy which included marketing regulations; were written in English; and concerned the period 1990–2013. Alcohol industry political activity was categorized into strategies/tactics and frames/arguments. Data extraction was undertaken by the lead author and 100% of the papers were fully second‐reviewed. Seventeen papers met the review criteria. Results Five main political strategies and five main frames were identified. The alcohol industry argues against marketing regulation by emphasizing industry responsibility and the effectiveness of self‐regulation, questioning the effectiveness of statutory regulation and by focusing on individual responsibility. Arguments relating to industry responsibility are often reinforced through corporate social responsibility activities. The industry primarily conveys its arguments through manipulating the evidence base and by promoting ineffective voluntary codes and non‐regulatory initiatives. Conclusions The alcohol industry's political activity is more varied than existing models of corporate political activity suggest. The industry's opposition to marketing regulation centres on claims that the industry is responsible and that self regulation is effective. There are considerable commonalities between tobacco and alcohol industry political activity, with differences due potentially to differences in policy contexts and perceived industry legitimacy. PMID:26173765

  18. How does the alcohol industry attempt to influence marketing regulations? A systematic review.

    Science.gov (United States)

    Savell, Emily; Fooks, Gary; Gilmore, Anna B

    2016-01-01

    To systematically review, using a qualitative, narrative synthesis approach, papers examining alcohol industry efforts to influence alcohol marketing policy, and compare with those used by the tobacco industry. Literature searches were conducted between April and July 2011, and updated in March 2013. Papers were included if they: made reference to alcohol industry efforts to influence (a) policy debates concerning marketing regulations, (b) new specific marketing policies or (c) broad alcohol policy which included marketing regulations; were written in English; and concerned the period 1990-2013. Alcohol industry political activity was categorized into strategies/tactics and frames/arguments. Data extraction was undertaken by the lead author and 100% of the papers were fully second-reviewed. Seventeen papers met the review criteria. Five main political strategies and five main frames were identified. The alcohol industry argues against marketing regulation by emphasizing industry responsibility and the effectiveness of self-regulation, questioning the effectiveness of statutory regulation and by focusing on individual responsibility. Arguments relating to industry responsibility are often reinforced through corporate social responsibility activities. The industry primarily conveys its arguments through manipulating the evidence base and by promoting ineffective voluntary codes and non-regulatory initiatives. The alcohol industry's political activity is more varied than existing models of corporate political activity suggest. The industry's opposition to marketing regulation centres on claims that the industry is responsible and that self regulation is effective. There are considerable commonalities between tobacco and alcohol industry political activity, with differences due potentially to differences in policy contexts and perceived industry legitimacy. © 2015 The Authors. Addiction published by John Wiley & Sons Ltd on behalf of Society for the Study of

  19. Valuing Health Using Time Trade-Off and Discrete Choice Experiment Methods: Does Dimension Order Impact on Health State Values?

    Science.gov (United States)

    Mulhern, Brendan; Shah, Koonal; Janssen, Mathieu F Bas; Longworth, Louise; Ibbotson, Rachel

    2016-01-01

    Health states defined by multiattribute instruments such as the EuroQol five-dimensional questionnaire with five response levels (EQ-5D-5L) can be valued using time trade-off (TTO) or discrete choice experiment (DCE) methods. A key feature of the tasks is the order in which the health state dimensions are presented. Respondents may use various heuristics to complete the tasks, and therefore the order of the dimensions may impact on the importance assigned to particular states. To assess the impact of different EQ-5D-5L dimension orders on health state values. Preferences for EQ-5D-5L health states were elicited from a broadly representative sample of members of the UK general public. Respondents valued EQ-5D-5L health states using TTO and DCE methods across one of three dimension orderings via face-to-face computer-assisted personal interviews. Differences in mean values and the size of the health dimension coefficients across the arms were compared using difference testing and regression analyses. Descriptive analysis suggested some differences between the mean TTO health state values across the different dimension orderings, but these were not systematic. Regression analysis suggested that the magnitude of the dimension coefficients differs across the different dimension orderings (for both TTO and DCE), but there was no clear pattern. There is some evidence that the order in which the dimensions are presented impacts on the coefficients, which may impact on the health state values provided. The order of dimensions is a key consideration in the design of health state valuation studies. Copyright © 2016. Published by Elsevier Inc.

  20. Order short-term memory is not specifically impaired in dyslexia and does not affect orthographic learning

    Directory of Open Access Journals (Sweden)

    Eva eStaels

    2014-09-01

    Full Text Available This article reports two studies that investigate short-term memory (STM deficits in dyslexic children and explores the relationship between short-term memory and reading acquisition. In the first experiment, thirty-six dyslexic children and sixty-one control children performed an item STM task and a serial order STM task. The results of this experiment show that dyslexic children do not suffer from a specific serial order STM deficit. In addition, the results demonstrate that phonological processing skills are as closely related to both item STM and serial order STM. However, nonverbal intelligence was more strongly involved in serial order STM than in item STM. In the second experiment, the same two STM tasks were administered and reading acquisition was assessed by measuring orthographic learning in a group of one hundred and eighty-eight children. The results of this study show that orthographic learning is exclusively related to item STM and not to order STM. It is concluded that serial order STM is not the right place to look for a causal explanation of reading disability, nor for differences in word reading acquisition.

  1. Does rumination mediate the relationship between emotion regulation ability and posttraumatic stress disorder?

    Directory of Open Access Journals (Sweden)

    Thomas Ehring

    2014-08-01

    Full Text Available Background and objectives: Trauma-related rumination has been suggested to be involved in the maintenance of posttraumatic stress disorder (PTSD. This view has empirically been supported by extensive evidence using cross-sectional, prospective, and experimental designs. However, it is unclear why trauma survivors engage in rumination despite its negative consequences. The current study aimed to explore the hypothesis that low emotion regulation ability underlies trauma-related rumination. Methods: Emotion regulation ability and trauma-related rumination were assessed in 93 road traffic accident survivors 2 weeks post-trauma. In addition, symptom levels of PTSD were assessed at 2 weeks as well as 1, 3, and 6 months follow-up. Results: Emotion regulation ability was significantly related to trauma-related rumination as well as levels of PTSD symptoms. In addition, the association between low emotion regulation ability and PTSD was mediated by rumination. Conclusions: The findings support the view that rumination is used as a dysfunctional emotion regulation strategy by trauma survivors.

  2. Does self-regulation capacity predict psychological well-being in physicians?

    Science.gov (United States)

    Simon, Christopher R; Durand-Bush, Natalie

    2015-01-01

    Despite increasing research on physician well-being, factors appearing to account for individual variation in levels of optimal functioning are largely unclear. One such factor could be self-regulation, which reflects how individuals effectively manage their thoughts, emotions and behaviours, and cope with adversity in their environment. The purpose of this study was to determine if self-regulation capacity could significantly predict psychological well-being in a sample of Canadian physicians. A total of 132 physicians completed the Scales of Psychological Well-Being and the short form of the Self-Regulation Questionnaire. Regression analyses confirmed the hypothesis that a significant amount of variance in levels of psychological well-being would be explained by self-regulation capacity. There was a particularly strong relationship between self-regulation capacity and the dimensions of purpose in life and environmental mastery, which suggests that physicians who effectively self-manage may be better able to preserve a sense of purpose and an adequate work-life balance in their daily life. Physicians today face consistently growing demands stemming from increasingly challenging work environments. Results of this study mark an important step in increasing our understanding of a potentially valuable skill that may help physicians to achieve well-being.

  3. Bank Risk-Taking Abroad : Does Home-Country Regulation and Supervision Matter

    NARCIS (Netherlands)

    Ongena, S.; Popov, A.; Udell, G.F.

    2011-01-01

    This paper provides the first empirical evidence on how home-country regulation and supervision affects bank risk-tailing in host-country markets. We analyze lending by 136 banks to 8,253 firms in 1,513 different localities across 13 countries. We find strong evidence that laxer regulatory

  4. Bank Risk-Taking Abroad : Does Home-Country Regulation and Supervision Matter

    NARCIS (Netherlands)

    Ongena, S.; Popov, A.; Udell, G.F.

    2011-01-01

    This paper provides the first empirical evidence on how home-country regulation and supervision affects bank risk-tailing in hostr-country markets. We analyze lending by 136 banks to 8,253 firms in 1,513 different localities across 13 countries. We find strong evidence that laxer regulatory

  5. How Does Self-Regulated Learning Relate to Active Procrastination and Other Learning Behaviors?

    Science.gov (United States)

    Yamada, Masanori; Goda, Yoshiko; Matsuda, Takeshi; Saito, Yutaka; Kato, Hiroshi; Miyagawa, Hiroyuki

    2016-01-01

    This research investigates the relationship between self-regulated learning awareness, procrastination, and learning behaviors in a blended learning environment. Participants included 179 first-grade university students attending a blended learning-style class that used a learning management system. Data were collected using questionnaires on…

  6. Does Using E-Portfolios for Reflective Writing Enhance High School Students' Self-Regulated Learning?

    Science.gov (United States)

    Chang, Chi-Cheng; Liang, Chaoyun; Shu, Kuen-Ming; Tseng, Kuo-Hung; Lin, Chun-Yu

    2016-01-01

    The study aims to examine whether reflective writing using e-portfolios enhances high school students' self-regulated learning. Participants included two classes of eighth-graders majoring in Information Processing and taking a course called "Website Design" at a vocational high school in Taiwan. There were 41 students, with 18 males and…

  7. Does Education Empower Women? The Regulated Empowerment of "Parhi Likhi" Women in Pakistan

    Science.gov (United States)

    Khurshid, Ayesha

    2017-01-01

    Through employing ethnographic data collected with female teachers from rural and low-income communities in Pakistan, this paper examines how parhi likhi (educated) women's access to valuable opportunities in public domains is contingent upon them becoming subject to new regulations, especially regarding their sexuality. This gendered process of…

  8. Neonatal immune challenge does not affect body weight regulation in rats.

    Science.gov (United States)

    Spencer, Sarah J; Mouihate, Abdeslam; Galic, Michael A; Ellis, Shaun L; Pittman, Quentin J

    2007-08-01

    The perinatal environment plays a crucial role in programming many aspects of adult physiology. Myriad stressors during pregnancy, from maternal immune challenge to nutritional deficiency, can alter long-term body weight set points of the offspring. In light of the increasing concern over body weight issues, such as obesity and anorexia, in modern societies and accumulating evidence that developmental stressors have long-lasting effects on other aspects of physiology (e.g., fever, pain), we explored the role of immune system activation during neonatal development and its impact on body weight regulation in adulthood. Here we present a thorough evaluation of the effects of immune system activation (LPS, 100 microg/kg ip) at postnatal days 3, 7, or 14 on long-term body weight, adiposity, and body weight regulation after a further LPS injection (50 microg/kg ip) or fasting and basal and LPS-induced circulating levels of the appetite-regulating proinflammatory cytokine leptin. We show that neonatal exposure to LPS at various times during the neonatal period has no long-term effects on growth, body weight, or adiposity. We also observed no effects on body weight regulation in response to a short fasting period or a further exposure to LPS. Despite reductions in circulating leptin levels in response to LPS during the neonatal period, no long-term effects on leptin were seen. These results convincingly demonstrate that adult body weight and weight regulation are, unlike many other aspects of adult physiology, resistant to programming by a febrile-dose neonatal immune challenge.

  9. KOREKSI ANGGAPAN BAZAAR ECONOMY, ORDER DAN REGULATION THEORY PADA ORIENTASI USAHA PKL KOTA SURAKARTA PASCA KRISIS MONETER

    Directory of Open Access Journals (Sweden)

    Joko Suwandi

    2013-06-01

    Full Text Available The particular objective of this research is to describe the orientation shift trend of vendor sellers business in Surakarta city prior, during and post the monetary crisis in order to obtain rectification of Bazaar Economy of Clifford Geertz, and Order Theory and Regulation Theory of Evers. H.D. This qualitative research of case study tried to describe the condition, activity and the development of vendor sellers’ orientation in Surakarta before (<1997, during (1997 to 2004 and after monetary crisis (2004-recently occurred in Indonesia, particularly in Surakarta city. The place of the research is in Surakarta city with the following data source; vendor sellers with all their activities, all the former public officials and officials associated to vendor sellers during and after the monetary crisis. The participants are selected through purposive sampling integrated with snowball sampling using key informant. The data are analyzed using interactive analysis from Miles and Huberman, through three stages activity namely, data reduction, data display, and conclusion drawing/verification. The conclusions of this research are as follows; 1 the vendor sellers’ orientation prior and during the monetary crisis comply to the informal sectors characteristics according to Clifford Geertz’s Bazaar Economy and Order Theory and Regulation Theory of Hans-Dieter Evers but the characteristics on post-monetary crisis have altered; 2 The vendor sellers’ characteristics after the monetary crisis can be classified into two namely the static group and dynamic group. The first group is dominated by vendor sellers, who have capital, management limitation and their business as subsistence. The later group is dominated by vendor sellers who have big capital, administered using modern management and have become the business to increase welfare. The inclination of orientation shift of vendor sellers in Surakarta city is developing slowly and developmental.

  10. Does lower birth order amplify the association between high socioeconomic status and central adiposity in young adult Filipino males?

    Science.gov (United States)

    Dahly, D L; Adair, L S

    2010-04-01

    To test the hypothesis that lower birth order amplifies the positive association between socioeconomic status and central adiposity in young adult males from a lower income, developing country context. The Cebu Longitudinal Health and Nutrition Survey is an ongoing community-based, observational study of a 1-year birth cohort (1983). 970 young adult males, mean age 21.5 years (2005). Central adiposity measured by waist circumference; birth order; perinatal maternal characteristics including height, arm fat area, age and smoking behavior; socioeconomic status at birth and in young adulthood. Lower birth order was associated with higher waist circumference and increased odds of high waist circumference, even after adjustment for socioeconomic status in young adulthood and maternal characteristics that could impact later offspring adiposity. Furthermore, the positive association between socioeconomic status and central adiposity was amplified in individuals characterized by lower birth order. This research has failed to reject the mismatch hypothesis, which posits that maternal constraint of fetal growth acts to program developing physiology in a manner that increases susceptibility to the obesogenic effects of modern environments.

  11. How often does the operating list follow the planned order? An analysis of elective maxillofacial operating lists.

    Science.gov (United States)

    Islam, Shofiq; Taylor, Christopher J; Ahmed, Siddiq; Ormiston, Ian W; Hayter, Jonathan P

    2015-12-01

    The authors explored consistency of the observed running order in operating sequence compared with prior scheduled listing. We analysed potential variables felt to be predictive in the chances of a patient having their procedure as previously scheduled. Data were retrospectively collected for a consecutive group of patients who underwent elective maxillofacial procedures over a four week period. The consistency of scheduled and observed running order was documented. We considered four independent variables (original list position, day of week, morning or afternoon list, seniority of surgeon) and analysed their relationship to the probability of a patient undergoing their operation as per listing. Logistic regression analysis was used to determine significant associations between predictor variables with an altered list order. Data were available for 35 lists (n = 133). 49% of lists were found to run according to prior given order, the remainder subject to some alteration. Logistic regression analysis showed a statistically significant association between original scheduled position and day of week, with list position consistency. Patients listed first were twelve times more likely to have their operation as listed compared to those placed fourth (OR 12.7, 95% CI 3.7-43, p lists at the start of a week were subject to less alteration (p lists showed some alteration to the previously printed order. It appears that being first on an elective list offers the greatest guarantee that a patient will have their operation as per prior schedule. It may be reasonable for clinicians to be mindful of potential operating list alterations when preparing their patients for elective surgery. Copyright © 2014 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

  12. Striking a balance: does nitrate uptake and metabolism regulate both NO generation and scavenging?

    DEFF Research Database (Denmark)

    Mur, Luis A J; Hebelstrup, Kim; Gupta, Kapuganti J

    2013-01-01

    Nitric oxide (NO) influences many aspects of plant development and responses to stress.The concentration of NO can play an important role in influencing its action (for example, in stomatal regulation; Wilson et al., 2009) so that the mechanisms through which NO content is modulated must...... be an important facet of NO research. Whilst NO generation mechanisms are clearly important, NO removal is of equal relevance, especially as plants will be continually exposed to NOx (NO + NO2) gases derived from soil microbial activity (Mur et al., 2013). Establishing and regulating a poise between NO generation......, NO fumigation from external sources and NO scavenging, which also needs to be flexible enough to change in response to a variety of physiological cues, is an under-considered aspect of plant NO biology...

  13. Water Services in the Buenos Aires Metropolitan Area: How Does State Regulation Work?

    Directory of Open Access Journals (Sweden)

    Mariela Verónica Rocca

    2014-08-01

    Full Text Available This article deals with the State regulation of drinking water and sanitation services in the Metropolitan Area of Buenos Aires. Its main objective is to identify the continuities and ruptures in State regulation during the transition from private management (1993-2006 to renationalisation and State management (2006 onwards. The concept of “State capacities” (both administrative and relational is used to assess regulatory performance. For the administrative capacities, the correspondence between the design and resources of the agencies, as well as the differences between their formal functions and actual practices, is examined. For the relational capacities, the policies of the National Government and its interaction with both the water and sanitation companies and the regulatory and control agencies are considered. The analysis is based on official documents, legislation and statistics, company balance sheets and reports, newspaper articles and semi-structured interviews.

  14. Does the intensity of prudential regulation affect banks? Evidence from the 2007-2009 crises

    Directory of Open Access Journals (Sweden)

    Isabel Argimon

    2012-08-01

    Full Text Available The main objective of this research is to gather empirical evidence on the effects of more or less stringency and more or less risk sensitivity in regulatory capital requirements on the observed behaviour of European banks during the initial years of the financial crisis. To do so, we use the indices built in Argimón and Ruiz (2010, which capture such characteristics of capital regulation. We test their incidence using changes in yearly data for individual banks for 25 countries of the European Union covering the period 2007-2009. Our results show that more stringency and risk sensitivity in capital regulation resulted in higher capital increases, with limited effect on risk taking. However, for well capitalized banks, higher risk sensitivity resulted in higher capital and higher risk, thus requiring striking the right balance, so as to lead to increased stability.

  15. Does a short self-compassion intervention for students increase healthy self-regulation?

    DEFF Research Database (Denmark)

    Dundas, Ingrid; Binder, Per Einar; Hansen, Tia G.B.

    2017-01-01

    negative self-directed thinking; as well as for self-compassion, anxiety and depression. Concluding, a short self-compassion course seems an effective method of increasing self-compassion and perceived control over one's life for university students, as well as increasing mental health.......The primary aim of this study was to examine the effects of a two-week self-compassion course on healthy self-regulation (personal growth self-efficacy and healthy impulse control) and unhealthy self-regulation (self-judgment and habitual negative self-directed thinking) in university students. We...... also examined the effects on self-compassion, anxiety and depression. Students (N = 158, 85% women, mean age = 25 years) were randomized to an intervention group and a waiting-list control group in a multi-baseline randomized control trial. Healthy self-control was measured by the Personal Growth...

  16. The Case of Dr. Oz: Ethics, Evidence, and Does Professional Self-Regulation Work?

    Science.gov (United States)

    Tilburt, Jon C; Allyse, Megan; Hafferty, Frederic W

    2017-02-01

    Dr. Mehmet Oz is widely known not just as a successful media personality donning the title "America's Doctor ® ," but, we suggest, also as a physician visibly out of step with his profession. A recent, unsuccessful attempt to censure Dr. Oz raises the issue of whether the medical profession can effectively self-regulate at all. It also raises concern that the medical profession's self-regulation might be selectively activated, perhaps only when the subject of professional censure has achieved a level of public visibility. We argue here that the medical profession must look at itself with a healthy dose of self-doubt about whether it has sufficient knowledge of or handle on the less visible Dr. "Ozes" quietly operating under the profession's presumptive endorsement. © 2017 American Medical Association. All Rights Reserved.

  17. Does quasi-long-range order in the two-dimensional XY model really survive weak random phase fluctuations?

    International Nuclear Information System (INIS)

    Mudry, Christopher; Wen Xiaogang

    1999-01-01

    Effective theories for random critical points are usually non-unitary, and thus may contain relevant operators with negative scaling dimensions. To study the consequences of the existence of negative-dimensional operators, we consider the random-bond XY model. It has been argued that the XY model on a square lattice, when weakly perturbed by random phases, has a quasi-long-range ordered phase (the random spin wave phase) at sufficiently low temperatures. We show that infinitely many relevant perturbations to the proposed critical action for the random spin wave phase were omitted in all previous treatments. The physical origin of these perturbations is intimately related to the existence of broadly distributed correlation functions. We find that those relevant perturbations do enter the Renormalization Group equations, and affect critical behavior. This raises the possibility that the random XY model has no quasi-long-range ordered phase and no Kosterlitz-Thouless (KT) phase transition

  18. Does interoceptive awareness affect the ability to regulate unfair treatment by others?

    Directory of Open Access Journals (Sweden)

    Mascha eVan 't Wout

    2013-11-01

    Full Text Available In this study we aimed to investigate how awareness of bodily responses, referred to as interoceptive awareness, influences decision-making in a social interactive context. Interoceptive awareness is thought to be crucial for adequate regulation of one’s emotions. However, there is a dearth of studies that examine the association between interoceptive awareness and the ability to regulate emotions during interpersonal decision-making. Here, we quantified interoceptive awareness with a heartbeat detection task in which we measured the difference between subjective self-reports and an objective psychophysiological measurement of participant heart rates. Social decision-making was quantified using a two-round Ultimatum Game. Participants were asked to first reject or accept an unfair division of money proposed by a partner. In turn, participants could then make an offer on how to divide an amount of money with the same partner. Participants performed 20 rounds of the two-round Ultimatum Game twice, once during baseline condition and once while asked to reappraise emotional reactions when confronted with unfair offers from partners. Results showed that after reappraisal participants 1 accepted more unfair offers and 2 offered higher return divisions, as compared to baseline. With respect to interoceptive awareness, participants with better heartbeat detection scores tended to report less emotional involvement when they applied reappraisal while playing the Ultimatum Game. However, there was no reliably significant relationship between heartbeat detection and the acceptance of unfair offers. Similarly, heartbeat detection accuracy was not related to return offers made in the second round of the Ultimatum Game or the habitual use of emotion regulation. These preliminary findings suggest that the relationship between interoceptive awareness and behavioral changes due to emotion regulation in a social decision-making context appears to be complex.

  19. Does body mass play a role in the regulation of food intake?

    Science.gov (United States)

    Speakman, John R; Stubbs, R James; Mercer, Julian G

    2002-11-01

    It is widely believed that body fatness (and hence total body mass) is regulated by a lipostatic feedback system. This system is suggested to involve at least one peripheral signalling compound, which signals to the brain the current size of body fat stores. In the brain the level of the signal is compared with a desirable target level, and food intake and energy expenditure are then regulated to effect changes in the size of body fat stores. There is considerable support for this theory at several different levels of investigation. Patterns of body-mass change in subjects forced into energy imbalance seem to demonstrate homeostasis, and long-term changes in body mass are minor compared with the potential changes that might result from energy imbalance. Molecular studies of signalling compounds have suggested a putative lipostatic signal (leptin) and a complex network of downstream processing events in the brain, polymorphisms of which lead to disruption of body-mass regulation. This network of neuropeptides provides a rich seam of potential pharmaceutical targets for the control of obesity. Despite this consistent explanation for the observed phenomena at several different levels of enquiry, there are alternative explanations. In the present paper we explore the possibility that the existence of lipostatic regulation of body fatness is an illusion generated by the links between body mass and energy expenditure and responses to energy imbalance that are independent of body mass. Using computer-based models of temporal patterns in energy balance we show that common patterns of change in body mass following perturbation can be adequately explained by this 'non-lipostatic' model. This model has some important implications for the interpretations that we place on the molecular events in the brain, and ultimately in the search for pharmaceutical agents for alleviation of obesity.

  20. Does rumination mediate the relationship between emotion regulation ability and posttraumatic stress disorder?

    OpenAIRE

    Ehring, Thomas; Ehlers, Anke

    2014-01-01

    Background and objectives: Trauma-related rumination has been suggested to be involved in the maintenance of posttraumatic stress disorder (PTSD). This view has empirically been supported by extensive evidence using cross-sectional, prospective, and experimental designs. However, it is unclear why trauma survivors engage in rumination despite its negative consequences. The current study aimed to explore the hypothesis that low emotion regulation ability underlies trauma-related rumination.Met...

  1. Does legal institutionalism rule out legal pluralism?
    Schmitt’s institutional theory and the problem of the concrete order

    Directory of Open Access Journals (Sweden)

    Mariano Croce

    2011-04-01

    Full Text Available The present paper explores the background of the institutional perspective of law that Carl Schmitt develops in On The Three Types of Juristic Thought (1934, and draws a comparison between this view and the institutional theory of Santi Romano (explicitly recalled by Schmitt. In doing so, I will shed some light on the complex relation between law and pluralism. While Schmitt portrays the law as a political means for preserving identity and excluding diversity within a homogeneous community, Romano depicts law as a form of organisation which inevitably reflects the plurality of social life.To this end, I will attend to some crucial problems of social and legal theory, such as the relation between norms and normality, the role of institutions in human life, and the way the law affects and is affected by the dynamics of its social surroundings.My final goal is to show that the law does not exclude pluralism at all, but is in itself a plural phenomenon.

  2. Sliding Mode Disturbance Observer-Based Fractional Second-Order Nonsingular Terminal Sliding Mode Control for PMSM Position Regulation System

    Directory of Open Access Journals (Sweden)

    Hong-Ru Li

    2015-01-01

    Full Text Available This paper investigates the position regulation problem of permanent magnet synchronous motor (PMSM subject to parameter uncertainties and external disturbances. A novel fractional second-order nonsingular terminal sliding mode control (F2NTSMC is proposed and the finite time stability of the closed-loop system is ensured. A sliding mode disturbance observer (SMDO is developed to estimate and make feedforward compensation for the lumped disturbances of the PMSM system. Moreover, the finite-time convergence of estimation errors can be guaranteed. The control scheme combining F2NTSMC and SMDO can not only improve performance of the closed-loop system and attenuate disturbances, but also reduce chattering effectively. Simulation results show that the proposed control method can obtain satisfactory position tracking performance and strong robustness.

  3. Does Being a Forerunner Give an Additional Survival Advantage? Gendered Order of Migration and Survival among Immigrant Women in Denmark

    DEFF Research Database (Denmark)

    Oksuzyan, Anna; Carollo, Angela; Mussino, Eleonora

    A substantial body of research has indicated that migrants enjoy better health and lower mortality compared to those born in the destination countries, the so called healthy migrant effect. Mortality differences in immigrants versus host population, however, differ by cause of death, country...... health outcomes compared to those who migrate for family reasons or as refugees, another aspect of migratory patterns, then order of migration is likely to be important to take into account when studying differences in health and survival across migrant groups and between the two genders. It has been...

  4. Does DNA methylation regulate metamorphosis? The case of the sea lamprey (Petromyzon marinus) as an example.

    Science.gov (United States)

    Covelo-Soto, Lara; Saura, María; Morán, Paloma

    2015-07-01

    Lampreys represent one of the most ancient vertebrate lineages enclosing a special interest for genetic and epigenetic studies. The sea lamprey (Petromyzon marinus) is an anadromous species that experiences metamorphosis all the way up to the adult stage. Although representing a gradual process, metamorphosis in this species involves dramatic conversions with regard to physiological together with structural body changes preparing individuals for a marine and parasitic life; in consequence, multiple gene expression modifications are expected. The implications of thyroid hormones and HOX gene expression changes have previously been reported in this species and also in other vertebrate species. Nonetheless, information lacks on how these genes are regulated in lampreys. We here report about the existence of methylation pattern differences between the adult and the larvae sea lamprey life cycle stages making use of the Methylation-Sensitive Amplified Polymorphism (MSAP) technique. Differentially methylated fragment sequencing allowed to establish homologous identities with HOX genes involved in morphogenesis, along with genes related to the water balance and to the osmotic homoeostasis, all associated to a marine environment adaptation. These results provide evidences revealing that DNA methylation plays a role in the epigenetic regulation of the P. marinus post-natal development representing a starting point for future studies. To the best of our knowledge, this is the first study which detects DNA methylation changes associated with metamorphosis in lampreys. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Does energy-price regulation benefit China's economy and environment? Evidence from energy-price distortions

    International Nuclear Information System (INIS)

    Ju, Keyi; Su, Bin; Zhou, Dequn; Wu, Junmin

    2017-01-01

    China's energy prices have long been regulated due to the critical role energy plays in economic growth and social development, which leads to energy-price distortion to some extent. To figure out whether energy-price regulations will benefit China's economy (measured by GDP growth) and environment (measured by carbon emissions), we conducted an in-depth simulation using path analysis, where five energy products (natural gas, gasoline, fuel oil, steam coal, and coking coal) are selected and three measurements (absolute, relative, and moving) of energy-price distortions are calculated. The results indicate that, with a series of energy pricing policies, the price distortion for a single type of energy has gradually transformed, while the energy pricing system in China is not fully market-oriented yet. Furthermore, China's economy benefits from relative and moving distortions, while the absolute distortions of energy prices have negative impacts on economic growth. Finally, with regard to the environment, carbon emissions call for fewer distortions. - Highlights: • Price distortion for a single type of energy has gradually transformed. • Energy pricing system in China is not yet fully market-oriented. • China's economy benefits from relative and moving distortions. • Absolute distortions of energy prices have negative effects on economic growth. • Carbon emissions call for less pricing distortions.

  6. How much does a regulator have to communicate, how and when?

    International Nuclear Information System (INIS)

    Dyers, J.E.; Boyle, M.L.; Gwozdecky, M.

    2006-01-01

    The conclusions and recommendations of this session can be summarized this way. - Challenges in communications can be directly due to the structure and politics of government at different levels.- A basic tenet is that journalists are different from the regulator and the industry, they may have a basic suspicion of technology and those who use it. - Two golden rules when communicating with the media: Always give them too much information and never miss a deadline. - Be true to the three basics of communication: Message - what you say. Myself - how you say it. Media - who you are talking to. Also, repetition can be an effective tool to stress the message that you are trying to convey.- Unfortunately, times change, the limits of full disclosure of information to the general public can be adversely affected by the actions of a few. Currently, the challenge in communications is the delivering the message of adequate level of safety and security without being able to discuss in detail why. - On emerging issues like risk of aircraft strikes after 9/11. Through a timely analysis and release of information, it makes easier to satisfy the needs of the public as evidenced by the short time span that this issue appeared in the media. - Implementation of a commitments document (with the help of consultant analyses, adoption of the European Foundation for Quality Management and its own soon to be effective FOI regulation and others) with those that it serve, is a challenging and effective way for improvement. (author)

  7. How does the regulator effectively involve the public in its activities?

    International Nuclear Information System (INIS)

    Sato, K.; Degueldre, D.

    2006-01-01

    As a variety of viewpoints and subjects were given in the different representations. The following is a summary: - Regulator commitments regarding public participation and experience gained in terms of effectiveness, visibility and credibility. The way the public hearings/meetings are organised and how they are used in the regulatory process. - How public participation is expected to be in the frame of the new proposed site selection procedure for radioactive waste disposal facility. This new process expects stakeholder involvement from the very beginning, even during the development of the site selection procedure itself, consisting of steps very precisely structured. - Regulator experience on responding to sensitive or 'high emotional' situations reminding the three main key-principles: (1) preparation to have an opportunity to have success; (2) always being honest, even during an 'emergency'; (3) start by understanding correctly the issue. - On how to speak about radioactivity to school children in the frame of an issue of a specific newspaper dedicated for children (8-12 years). Additional local actions in schools were also mentioned. (author)

  8. Eye Absence Does Not Regulate Planarian Stem Cells during Eye Regeneration.

    Science.gov (United States)

    LoCascio, Samuel A; Lapan, Sylvain W; Reddien, Peter W

    2017-02-27

    Dividing cells called neoblasts contain pluripotent stem cells and drive planarian flatworm regeneration from diverse injuries. A long-standing question is whether neoblasts directly sense and respond to the identity of missing tissues during regeneration. We used the eye to investigate this question. Surprisingly, eye removal was neither sufficient nor necessary for neoblasts to increase eye progenitor production. Neoblasts normally increase eye progenitor production following decapitation, facilitating regeneration. Eye removal alone, however, did not induce this response. Eye regeneration following eye-specific resection resulted from homeostatic rates of eye progenitor production and less cell death in the regenerating eye. Conversely, large head injuries that left eyes intact increased eye progenitor production. Large injuries also non-specifically increased progenitor production for multiple uninjured tissues. We propose a model for eye regeneration in which eye tissue production by planarian stem cells is not directly regulated by the absence of the eye itself. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. Does Birth Order and Academic Proficiency Influence Perfectionistic Self-presentation Among Undergraduate Engineering Students? A Descriptive Analysis.

    Science.gov (United States)

    Louis, Preeti Tabitha; Kumar, Navin

    2016-01-01

    Perfectionism is a multifaceted concept. It had both advantages and disadvantages. Perfectionistic traits have been associated with leadership and very intellectual people. The present study is an attempt to understand if engineering students possess perfectionistic orientation and whether it influences self-efficacy, social connectedness, and achievement motivation. The present study adopts a random sampling design to evaluate the presence of perfectionism as a personality trait among undergraduate engineering students ( N = 320). Standardized inventories such as Almost Perfect Scale-Revised were administered first to identify perfectionists and second to differentiate the adaptive from the maladaptive perfectionists. Scheduled interviews were conducted with students to obtain information regarding birth order and family functioning. Findings from the study reveal that there were a significant number of maladaptive perfectionists and that they experienced higher levels of personal and societal demands leading to a negative emotional well-being in comparison to the adaptive perfectionists. We also observed that first-born children were more likely to display a perfectionistic self-presentation and from scheduled interviews, we understood that paternal influences were stronger when it came to decision-making and display of conscientiousness. The study draws on important implications for helping students to understand perfectionism and to respond to demands of the family and societal subsystems in a positive and an adaptive manner.

  10. Does Birth Order and Academic Proficiency Influence Perfectionistic Self-presentation Among Undergraduate Engineering Students? A Descriptive Analysis

    Science.gov (United States)

    Louis, Preeti Tabitha; Kumar, Navin

    2016-01-01

    Background: Perfectionism is a multifaceted concept. It had both advantages and disadvantages. Perfectionistic traits have been associated with leadership and very intellectual people. The present study is an attempt to understand if engineering students possess perfectionistic orientation and whether it influences self-efficacy, social connectedness, and achievement motivation. Materials and Methods: The present study adopts a random sampling design to evaluate the presence of perfectionism as a personality trait among undergraduate engineering students (N = 320). Standardized inventories such as Almost Perfect Scale-Revised were administered first to identify perfectionists and second to differentiate the adaptive from the maladaptive perfectionists. Scheduled interviews were conducted with students to obtain information regarding birth order and family functioning. Results: Findings from the study reveal that there were a significant number of maladaptive perfectionists and that they experienced higher levels of personal and societal demands leading to a negative emotional well-being in comparison to the adaptive perfectionists. We also observed that first-born children were more likely to display a perfectionistic self-presentation and from scheduled interviews, we understood that paternal influences were stronger when it came to decision-making and display of conscientiousness. Conclusion: The study draws on important implications for helping students to understand perfectionism and to respond to demands of the family and societal subsystems in a positive and an adaptive manner. PMID:27833225

  11. TREE CANOPY PRUNING DOES NOT REGULATE BIENNIAL BEARING IN ”ELSTAR” APPLE (Malus domestica Borkh.

    Directory of Open Access Journals (Sweden)

    Nikola Pavičić

    2004-12-01

    Full Text Available Four alternative pruning strategies (A– 25 generative buds, B– 50 generative buds, C– 75 generative buds and D–100 generative buds per tree for Elstar apple cultivar and their possible impact on improvement in productivity were examined in 1999 and 2000. Year was significant factor for all traits, except yield. The pruning strategy is significant for number of fruits per flower cluster and fruit mass. Interaction year and pruning strategy is significant only for number of fruits per flower cluster. Fruit mass was larger for pruning strategy A compared to the pruning strategies C and D. Yield efficiency and biennial bearing index were not affected by pruning strategies. The biennial bearing index variance was the lowest for the pruning strategy B. Trunk cross sectional area (TCSA had negative impact on fruit mass in pruning strategy C. Correlation between the flower and crop density was positive in pruning strategy A. Flower density was in positive correlation with yield in pruning strategy C. The research shows that tree pruning alone will not result in adequate yield regulation in ‘Elstar’ apple.

  12. Why does it matter how we regulate the use of human body parts?

    Science.gov (United States)

    Goold, Imogen

    2014-01-01

    Human tissue and body parts have been used in one way or another for millennia. They have been preserved and displayed, both in museums and public shows. Real human hair is used for wigs, while some artists even use human tissue in their works. Blood, bone marrow, whole organs and a host of other structures and human substances are all transplanted into living persons to treat illness. New life can be created from gametes through in vitro fertilisation (IVF), while the creation of cell lines keeps tissue alive indefinitely. These uses create significant challenges for the legal system in the UK. The major challenge for the law is to balance the competing demands of those groups who have vested interests in human tissue-researchers, medical practitioners, patients, families, the community and the police, among many others. It must provide sufficient control to users of tissue, but also take account of the fact that our bodies hold psychological importance for us while we live and, after we die, for those we leave behind. To some degree the law has been successful, but we still lack a comprehensive, coherent approach to the regulation of human tissue. Partially as a reaction to this lack of a comprehensive approach, some commentators have turned to applying the concept of property to human tissue means to achieve regulatory outcomes they support.

  13. Does dietary iodine regulate oxidative stress and adiponectin levels in human breast milk?

    Science.gov (United States)

    Gutiérrez-Repiso, Carolina; Velasco, Inés; Garcia-Escobar, Eva; Garcia-Serrano, Sara; Rodríguez-Pacheco, Francisca; Linares, Francisca; Ruiz de Adana, Maria Soledad; Rubio-Martin, Elehazara; Garrido-Sanchez, Lourdes; Cobos-Bravo, Juan Francisco; Priego-Puga, Tatiana; Rojo-Martinez, Gemma; Soriguer, Federico; García-Fuentes, Eduardo

    2014-02-10

    Little is known about the association between iodine and human milk composition. In this study, we investigated the association between iodine and different markers of oxidative stress and obesity-related hormones in human breast milk. This work is composed of two cross-sectional studies (in lactating women and in the general population), one prospective and one in vitro. In the cross-sectional study in lactating women, the breast milk iodine correlated negatively with superoxide dismutase (SOD), catalase, and glutathione peroxidase (GSH-Px) activities, and with adiponectin levels. An in vitro culture of human adipocytes with 1 μM potassium iodide (KI, dose similar to the human breast milk iodine concentration) produced a significant decrease in adiponectin, GSH-Px, SOD1, and SOD2 mRNA expression. However, after 2 months of treatment with KI in the prospective study, a positive correlation was found between 24-h urinary iodine and serum adiponectin. Our observations lead to the hypothesis that iodine may be a factor directly involved in the regulation of oxidative stress and adiponectin levels in human breast milk.

  14. The Nlrp3 Inflammasome Does Not Regulate Alloimmunization to Transfused Red Blood Cells in Mice

    Directory of Open Access Journals (Sweden)

    David R. Gibb

    2016-07-01

    Full Text Available Red blood cell (RBC transfusions are essential for patients with hematological disorders and bone marrow failure syndromes. Despite ABO matching, RBC transfusions can lead to production of alloantibodies against “minor” blood group antigens. Non-ABO alloimmunization is a leading cause of transfusion-associated mortality in the U.S. Despite its clinical importance, little is known about the immunological factors that promote alloimmunization. Prior studies indicate that inflammatory conditions place patients at higher risk for alloimmunization. Additionally, co-exposure to pro-inflammatory pathogen associated molecular patterns (PAMPs promotes alloimmunization in animal models, suggesting that RBC alloimmunization depends on innate immune cell activation. However, the specific innate immune stimuli and sensors that induce a T cell-dependent alloantibody response to transfused RBCs have not been identified. The NLRP3 inflammasome senses chemically diverse PAMPs and damage associated molecular patterns (DAMPs, including extracellular ATP and iron-containing heme. We hypothesized that activation of the NLRP3 inflammasome by endogenous DAMPs from RBCs promotes the alloimmune response to a sterile RBC transfusion. Using genetically modified mice lacking either NLRP3 or multiple downstream inflammasome response elements, we ruled out a role for the NLRP3 inflammasome or any Caspase-1 or -11 dependent inflammasome in regulating RBC alloantibody production to a model antigen.

  15. Ministerial Order of 24 April 1964 on the approval of types of devices containing radioactive substances, made in implementation of Section 3.1 d/2 of the Royal Order of 28 February 1963 embodying the General Regulations for the Protection of the Population and Workers against the Hazards of Ionizing Radiations

    International Nuclear Information System (INIS)

    1964-01-01

    This Order lays down that approval of devices containing radioactive substances and referred to in the Royal Order of 28 February 1963 embodying the General Regulations on Protection of the Population and Workers against the Hazards of Ionizing Radiations will only be granted if the total quantity of radioisotopes contained therein does not exceed certain values laid down by the 1963 Royal Order, and the radioactive substances are adequately shielded. It also lays down the procedure to be complied with for obtaining such approval and the conditions the applicant must meet to obtain the certificate of approval, which is valid for six years and may be renewed. The Ministry of Employment and Labour, Institute of Hygiene and Epidemiology, and the Ministry of Public Health and the Family are the competent authorities in respect of applications for a certificate of approval. Finally, suspension or withdrawal of the certificate or confiscation of the radioactive substances or devices do not give rise to compensation. (NEA) [fr

  16. Carbachol does not down-regulate substance P receptors in pancreatic acini.

    Science.gov (United States)

    Patto, R J; Vinayek, R; Jensen, R T; Gardner, J D

    1992-01-01

    In a previous study, we found that first incubating guinea pig pancreatic acini with carbachol caused desensitization of the enzyme secretory response to cholecystokinin-octapeptide (CCK-8), bombesin, and carbachol but not that to substance P. This carbachol-induced desensitization could be accounted for by carbachol-induced down-regulation of receptors for CCK-8, bombesin, and carbachol. Although carbachol did not desensitize the enzyme secretory response to substance P, an effect of carbachol on substance P receptors was not examined. In the present study, in dispersed acini from guinea pig pancreas, substance P caused a twofold increase in amylase secretion. Stimulation was half-maximal at 0.7 nM and was maximal at 10 nM. Analysis of the ability of substance P to inhibit binding of 125I-substance P to substance P receptors indicated that acini possess a single class of receptors for substance P (Kd = 0.8 +/- 0.1 nM; Bmax = 1,037 +/- 145 fmol/mg of DNA). There was a close correlation between the relative potency with which substance P stimulated amylase secretion (0.7 nM) and the potency for inhibiting binding of 125I-substance P (Kd = 0.8 nM). First incubating pancreatic acini with carbachol did not alter either substance P-stimulated enzyme secretion or binding of 125I-substance P to substance P receptors, whereas in the same experiments, carbachol reduced binding of 125I-CCK-8 to cholecystokinin receptors by 50% and decreased in CCK-8-stimulated enzyme secretion by 50%.(ABSTRACT TRUNCATED AT 250 WORDS)

  17. Order for execution of the law concerning regulations of nuclear source materials, nuclear fuel materials and reactors

    International Nuclear Information System (INIS)

    1979-01-01

    The order is enacted under the law for the regulations of nuclear source materials, nuclear fuel materials and reactors. Any person who engages in refining business shall get designation for each works or place of enterprise. The application shall be filed through the director of International Trade and Industry Office in charge of the location of the works or the enterprise with a business program and other specified documents attached. Any person who undertakes processing business shall get permission for each works or place of enterprise. The application shall be submitted with a business program and other documents defined by the Ordinance of the Prime Minister's Office. Any person who sets up reactor shall get permission for each works or place of enterprise. The application shall be presented with a financial project and other documents stipulated by the ordinance. Fast breeding reactor, heavy-water moderated boiling water reactor and light-water moderated pressurized water reactor are designated as reactor in the phase of research and development. Each foreign nuclear ship equipped with reactor which enters into Japanese waters shall get permission of the Minister of Transport. The application shall be presented with the papers explaining safety of reactor facilities and other documents provided by the ordinance of the ministry concerned. (Okada, K.)

  18. Deducing the temporal order of cofactor function in ligand-regulated gene transcription: theory and experimental verification.

    Science.gov (United States)

    Dougherty, Edward J; Guo, Chunhua; Simons, S Stoney; Chow, Carson C

    2012-01-01

    Cofactors are intimately involved in steroid-regulated gene expression. Two critical questions are (1) the steps at which cofactors exert their biological activities and (2) the nature of that activity. Here we show that a new mathematical theory of steroid hormone action can be used to deduce the kinetic properties and reaction sequence position for the functioning of any two cofactors relative to a concentration limiting step (CLS) and to each other. The predictions of the theory, which can be applied using graphical methods similar to those of enzyme kinetics, are validated by obtaining internally consistent data for pair-wise analyses of three cofactors (TIF2, sSMRT, and NCoR) in U2OS cells. The analysis of TIF2 and sSMRT actions on GR-induction of an endogenous gene gave results identical to those with an exogenous reporter. Thus new tools to determine previously unobtainable information about the nature and position of cofactor action in any process displaying first-order Hill plot kinetics are now available.

  19. A linguistic representation of the regulation of transcription initiation. I. An ordered array of complex symbols with distinctive features.

    Science.gov (United States)

    Collado-Vides, J

    1993-01-01

    The inadequacy of context-free grammars in the description of regulatory information contained in DNA gave the formal justification for a linguistic approach to the study of gene regulation. Based on that result, we have initiated a linguistic formalization of the regulatory arrays of 107 sigma 70 E. coli promoters. The complete sequences of promoter (Pr), operator (Op) and activator binding sites (I) have previously been identified as the smallest elements, or categories, for a combinatorial analysis of the range of transcription initiation of sigma 70 promoters. These categories are conceptually equivalent to phonemes of natural language. Several features associated with these categories are required in a complete description of regulatory arrays of promoters. We have to select the best way to describe the properties that are pertinent for the description of such regulatory regions. In this paper we define distinctive features of regulatory regions based on the following criteria: identification of subclasses of substitutable elements, simplicity, selection of the most directly related information, and distinction of one array among the whole set of promoters. Alternative ways to represent distances in between regulatory sites are discussed, permitting, together with a principle of precedence, the identification of an ordered set of complex symbols as a unique representation for a promoter and its associated regulatory sites. In the accompanying paper additional distinctive features of promoters and regulatory sites are identified.

  20. 75 FR 27631 - Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Salable...

    Science.gov (United States)

    2010-05-18

    ..., Marketing Specialist or Gary D. Olson, Regional Manager, Northwest Marketing Field Office, Marketing Order... creation of the marketing order, can create liquidity problems for some producers. The marketing order was...

  1. 75 FR 13445 - Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Salable...

    Science.gov (United States)

    2010-03-22

    ... Manager, Northwest Marketing Field Office, Marketing Order Administration Branch, Fruit and Vegetable... creation of the marketing order, can create liquidity problems for some producers. The marketing order was... 22, 2010 / Proposed Rules#0;#0; [[Page 13445

  2. 76 FR 11971 - Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Salable...

    Science.gov (United States)

    2011-03-04

    ... Manager, Northwest Marketing Field Office, Marketing Order Administration Branch, Fruit and Vegetable... create liquidity problems for some producers. The marketing order was designed to reduce the price... 4, 2011 / Proposed Rules#0;#0; [[Page 11971

  3. 78 FR 78165 - Orders: Reporting by Regulated Entities of Stress Testing Results as of September 30, 2013...

    Science.gov (United States)

    2013-12-26

    ... Instructions and Guidance AGENCY: Federal Housing Finance Agency. ACTION: Orders. SUMMARY: In this document... is amending the Summary Instructions and Guidance, which accompanied the Orders. DATES: Each Order is effective November 26, 2013. FOR FURTHER INFORMATION CONTACT: Naa Awaa Tagoe, Senior Associate Director...

  4. SNF project's MCO compliance assessment with DOE ''general design criteria,'' order 6430.1A and ''SNF project MCO additional NRC requirements,'' HNF-SD-SNF-DB-005

    International Nuclear Information System (INIS)

    GOLDMANN, L.H.

    1999-01-01

    This document is presented to demonstrate the MCOs compliance to the major design criteria invoked on the MCO. This document is broken down into a section for the MCO's evaluation against DOE Order 6430.1A General Design Criteria sixteen divisions and then the evaluation of the MCO against HNF-SD-SNF-DB-005 ''Spent Nuclear Fuel Project Multi-Canister Overpack Additional NRC Requirements.'' The compliance assessment is presented as a matrix in tabular form. The MCO is the primary container for the K-basin's spent nuclear fuel as it leaves the basin pools and through to the 40 year interim storage at the Canister Storage Building (CSB). The MCO and its components interface with; the K basins, shipping cask and transportation system, Cold Vacuum Drying facility individual process bays and equipment, and CSB facility including the MCO handling machine (MHM), the storage tubes, and the MCO work stations where sampling, welding, and inspection of the MCO is performed. As the MCO is the primary boundary for handling, process, and storage, its main goals are to minimize the spread of its radiological contents to the outside of the MCO and provide for nuclear criticality control. The MCO contains personnel radiation shielding only on its upper end, in the form of a shield plug, where the process interfaces are located. Shielding beyond the shield plug is the responsibility of the using facilities. The design of the MCO and its components is depicted in drawings H-2-828040 through H-2-828075. Not every drawing number in the sequence is used. The first drawing number, H-2-828040, is the drawing index for the MCO. The design performance specification for the MCO is HW-S-0426, and was reviewed and approved by the interfacing design authorities, the safety, regulatory, and operations groups, and the local DOE office. The current revision for the design performance specification is revision 5. The designs of the MCO have been reviewed and approved in a similar way and the reports

  5. Royal Order of 24 May 1977 amending the Royal Order of 28 February 1963 on General Regulations for Protection of the Population and Workers against the Hazards of Ionizing Radiations

    International Nuclear Information System (INIS)

    1977-01-01

    This Royal Order amends the Royal Order of 28 February 1963, as revised, embodying the General Regulations for the Protection of the Population and Workers against the Hazards of Ionizing Radiations. The amendment refers in particular to the conditions for the direct supply by manufacturers or importers of unsealed radioactive substances, radioisotopes or preparations containing them, to duly authorized physicians, veterinary surgeons and chemists. It also refers to the conditions of use of devices and substances emitting ionizing radiations, as well as to the licensing conditions for holders of isotopes and the qualifications of users. (NEA) [fr

  6. Royal Order of 22 April 1974 on Establishment of Fees in Implementation of Regulations on Protection at Work, Protection against Hazardous Equipment and Ionizing Radiations and amending the General Regulations on Protection at Work

    International Nuclear Information System (INIS)

    1974-01-01

    This Order was made in implementation of the Act of 3 December 1969 empowering the King to establish fees in application of regulations on protection at work, dangerous equipment and ionizing radiations. In particular, it sets fees for the licensing procedure for establishment classified according to the General Regulations for the Protection of the Population and Workers against the Hazards of Ionizing Radiations of 28 February 1963. (NEA) [fr

  7. Order no. 53/71 of 3 February 1971 - Approval of the General Regulations on Health and Safety at Work in Industrial Establishments

    International Nuclear Information System (INIS)

    1971-01-01

    This Order approves the General Regulations for Health and Safety at Work in Industrial Establishments. Section V which concerns ionizing radiations lays down that radiation protection measures currently in force must be observed in all premises where radioactive substances are stored, handled or used and where devices producing ionizing radiations are operated. (NEA) [fr

  8. Improving CS regulations.

    Energy Technology Data Exchange (ETDEWEB)

    Nesse, R.J.; Scheer, R.M.; Marasco, A.L.; Furey, R.

    1980-10-01

    President Carter issued Executive Order 12044 (3/28/78) that required all Federal agencies to distinguish between significant and insignificant regulations, and to determine whether a regulation will result in major impacts. This study gathered information on the impact of the order and the guidelines on the Office of Conservation and Solar Energy (CS) regulatory practices, investigated problems encountered by the CS staff when implementing the order and guidelines, and recommended solutions to resolve these problems. Major tasks accomplished and discussed are: (1) legislation, Executive Orders, and DOE Memoranda concerning Federal administrative procedures relevant to the development and analysis of regulations within CS reviewed; (2) relevant DOE Orders and Memoranda analyzed and key DOE and CS staff interviewed in order to accurately describe the current CS regulatory process; (3) DOE staff from the Office of the General Counsel, the Office of Policy and Evaluation, the Office of the Environment, and the Office of the Secretary interviewed to explore issues and problems encountered with current CS regulatory practices; (4) the regulatory processes at five other Federal agencies reviewed in order to see how other agencies have approached the regulatory process, dealt with specific regulatory problems, and responded to the Executive Order; and (5) based on the results of the preceding four tasks, recommendations for potential solutions to the CS regulatory problems developed. (MCW)

  9. Order for execution of the law concerning regulations of nuclear source materials, nuclear fuel materials and reactors

    International Nuclear Information System (INIS)

    1987-01-01

    Chapeter 1 specifies regulations concerning business management for refining and processing, which cover application for designation of refining operation, application for permission for processing operation, and approval of personnel responsible for handling nuclear fuel. Chapter 2 specifies regulations concerning construction and operation of nuclear reactors, which cover application for construction of nuclear reactors, reactors in a research and development stage, application for permission concerning nuclear reactors mounted on foreign nuclear powered ships, application for permission for alteration concerning construction of nuclear reactors, application for permission for alteration concerning nuclear reactors mounted on foreign nuclear powered ships, nuclear reactor facilities to be subjected to regular inspection, nuclear reactor for which submission of operation plan is not required, and application for permission for transfer of nuclear reactor. Chapter 2 also specifies regulations concerning business management for reprocessing and waste disposal. Chapter 3 stipulates regulations concerning use of nuclear fuel substances, nuclear material substances and other substances covered by international regulations, which include rules for application for permission for use of nuclear fuel substances, etc. Supplementary provisions are provided in Chapter 4. (Nogami, K.)

  10. 10 CFR Appendix A to Part 603 - Applicable Federal Statutes, Executive Orders, and Government-wide Regulations

    Science.gov (United States)

    2010-01-01

    ... REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Pt. 603, App. A Appendix A to Part 603—Applicable Federal.... Prohibitions on discrimination on the basis of race, color, or national origin in Title VI of the Civil Rights... origin. 2. If the RD&D involves human subjects or animals, it is subject to the requirements codified by...

  11. 21 CFR 10.50 - Promulgation of regulations and orders after an opportunity for a formal evidentiary public hearing.

    Science.gov (United States)

    2010-04-01

    ... public hearing. (2) The person requesting the hearing has a right to an opportunity for a hearing and... action an opportunity for a formal evidentiary public hearing as listed below. The list imparts no right...) on regulations for animal antibiotic drugs and certification requirements. (13) Section 721 (b) and...

  12. The Research on Second-Order ADRC Algorithm of Using Wind Turbine Virtual Inertia to Participate in Primary Frequency Regulation in a Small Stand-Alone Microgrid

    Directory of Open Access Journals (Sweden)

    Wang Yi

    2018-01-01

    Full Text Available In order to improve the transient stability of frequency in a small stand-alone microgrid (SSM, this paper takes a SSM composed of a direct-drive permanent magnet synchronous generator (D-PMSG and a micro gas turbine (MGT as the background and uses wind turbine generator (WTG virtual inertia (VI to participate in the primary (short-term system frequency regulation. First of all, this paper constructs a grid-connected model composed of a WTG and a MGT, analyzes the WTG virtual inertia frequency regulation mechanism, and explains the principle of proportional-differentiation (PD virtual inertia control (VIC and its shortcomings. Secondly, the paper introduces the structure principle of n-order active disturbance rejection control (ADRC and deduces the design process of second-order ADRC-VIC. Finally, through the simulation and experimental verification, comparing the frequency perturbation of without-VIC, PD-VIC, and ADRC-VIC, it is concluded that PD-VIC and ADRC-VIC both can use the WTG virtual inertia to participate in the primary frequency regulation. The frequency regulation effect of ADRC-VIC is better than PD-VIC, ADRC-VIC can extend the rotor speed recovery time and avoid overshoot, and its frequency fluctuation amplitude and settling time are obviously improved, and ADRC-VIC can effectively avoid the overshoot phenomenon of the MGT output power.

  13. 78 FR 22202 - Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Salable...

    Science.gov (United States)

    2013-04-15

    ... is produced outside of the U.S., with China and India being the largest global competitors of... entities, the volume control feature of this order has small entity orientation. This proposed rule would...

  14. 77 FR 33076 - Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Salable...

    Science.gov (United States)

    2012-06-05

    ... competitors of domestic Scotch spearmint oil production. The Far West's share of total global Scotch spearmint... entities, the volume control feature of this order has small entity orientation. This final rule...

  15. The new Portuguese law on surrogacy - The story of how a promising law does not really regulate surrogacy arrangements.

    Science.gov (United States)

    Raposo, Vera Lúcia

    2017-09-01

    Since 2006, surrogacy arrangements have been expressly forbidden within the Portuguese legal order, in any one of its forms, and in some situations, it has even been criminalised. However, since August 2016, surrogacy has been allowed under certain restrictive scenarios, providing it follows several prerequisites. In spite of this progress, the 2016 amendment to the law has not been immune to criticism. One of its most debatable aspects is the lack of the surrogate's right to regret, although it is doubtful that surrogacy contracts will be enforced against a surrogate's wishes. But the weakest point of the new law is its failure to address some of the nuclear issues of surrogacy contracts, leaving solutions either to general contract law or to the clauses stipulated by the parties. Furthermore, it is unclear which clauses are allowed and which are forbidden under the law. This study describes the content of the new Portuguese surrogacy law, exposes its main fragilities and suggests solutions for matters not covered by the law. The conclusion is that a law full of promise fails regarding the issues it is supposed to regulate.

  16. Fractional order nonlinear variable speed and current regulation of a permanent magnet synchronous generator wind turbine system

    Directory of Open Access Journals (Sweden)

    Anitha Karthikeyan

    2018-03-01

    Full Text Available In this paper we derived the fractional order model of the Permanent Magnet Synchronous Generator (PMSG from its integer model. The PMSG was employing a shaft sensor for the speed sensing and control. But this sensor would increase the hardware complexity as well as the cost of the system. Hence we have developed a Fractional order Nonlinear adaptive control method for speed and current tracking of the PMSG. The objective of an adaptive controller is to first define a virtual control state and force it to become a stabilizing function in accordance with a corresponding error dynamics. In order to study the Lyapunov exponents of the fractional order controller, we proposed a new method which would remove the complexity of finding the sign of the Lyapunov first derivative. The Fractional order control scheme is implemented in LabVIEW for simulation results. The simulation results indicated that the estimated rotor position and speed correspond to their actual values well. Keywords: Chaos suppression, Fractional order systems, Permanent magnet synchronous generator, Speed and current control, Lyapunov stability

  17. Development of an analogue multiplexed regulation for periodic 1. order delayed processes; Etude et realisation d'une regulation analogique multiplexee pour processus aperiodiques du 1. ordre avec retard pur

    Energy Technology Data Exchange (ETDEWEB)

    Amblard, J C [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1967-07-15

    The present note deals with the study regulations of the sampled type, for 1. order process with simple delay. In order to obtain a good stability in such regulations, together with acceptable performances, it is interesting to use polynomial type correctors acting directly on the sampled error signals. The active elements of these correctors can be shared by all the channels to be controlled. Furthermore, the determination of the correction parameters results from an optimal study of the system. In the second part is described the construction of a multiplexed regulation for diffusion ovens. (author) [French] La presente note concerne l'etude des regulations de type echantillonne, pour processus du 1. ordre avec retard pur. Pour obtenir une bonne stabilite de telles regulations, ainsi que des performances correcte il est interessant d'utiliser des correcteurs de type polynomial, agissant directement sur les signaux d'erreur echantillonnes. Les elements actifs de ces correcteurs peuvent etre pris communs a toutes les voies a controler. D'autre part, la determination des parametres de correction decoula d'une etude optimale du systeme. Dans une seconde partie on decrit la realisation d'une regulation multiplexee de fours a diffusion. (auteur)

  18. Development of an analogue multiplexed regulation for periodic 1. order delayed processes; Etude et realisation d'une regulation analogique multiplexee pour processus aperiodiques du 1. ordre avec retard pur

    Energy Technology Data Exchange (ETDEWEB)

    Amblard, J.C. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1967-07-15

    The present note deals with the study regulations of the sampled type, for 1. order process with simple delay. In order to obtain a good stability in such regulations, together with acceptable performances, it is interesting to use polynomial type correctors acting directly on the sampled error signals. The active elements of these correctors can be shared by all the channels to be controlled. Furthermore, the determination of the correction parameters results from an optimal study of the system. In the second part is described the construction of a multiplexed regulation for diffusion ovens. (author) [French] La presente note concerne l'etude des regulations de type echantillonne, pour processus du 1. ordre avec retard pur. Pour obtenir une bonne stabilite de telles regulations, ainsi que des performances correcte il est interessant d'utiliser des correcteurs de type polynomial, agissant directement sur les signaux d'erreur echantillonnes. Les elements actifs de ces correcteurs peuvent etre pris communs a toutes les voies a controler. D'autre part, la determination des parametres de correction decoula d'une etude optimale du systeme. Dans une seconde partie on decrit la realisation d'une regulation multiplexee de fours a diffusion. (auteur)

  19. Does Self-Regulated Learning-Skills Training Improve High-School Students' Self-Regulation, Math Achievement, and Motivation While Using an Intelligent Tutor?

    Science.gov (United States)

    Barrus, Angela

    2013-01-01

    This study empirically evaluated the effectiveness of the instructional design, learning tools, and role of the teacher in three versions of a semester-long, high-school remedial Algebra I course to determine what impact self-regulated learning skills and learning pattern training have on students' self-regulation, math achievement, and…

  20. How it can assist in compliance with the DOE`S new 10 CFR 835 and the NRC`S 10 CFR 20 regulation

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, W.H. [NFS Radiation Protection Systems, Inc., Erwin, TN (United States)

    1995-02-01

    With new government regulations on the horizon, advanced technology will become a necessity for the accurate assessment of air sampling data and maintaining internal dose ALARA. Bar coding is one advanced technology which has provided significant improvements in radiological air sampling. When combined with specific hardware and software, bar code technology can be used to automate procedures and enhance the data accuracy associated with air sampling in the workplace. This paper discusses some of the regulatory issues regarding radiological air sampling and describes how improved bar coded accountability techniques can assist in regulatory compliance.

  1. 78 FR 30231 - Defense Federal Acquisition Regulation Supplement: Clarification of “F” Orders in the Procurement...

    Science.gov (United States)

    2013-05-22

    ... supplementary procurement instrument identification numbers. DATES: Effective: May 22, 2013. FOR FURTHER... the use of ``F'' in the 9th position of the PIIN to those orders and calls issued by DoD under... by an ``F'' in the 9th position of the PIIN, field activities would no longer be able to pull data...

  2. 17 June 1992 - Royal Order amending the Royal Order of 28 February 1963 laying down the General Regulations for protection of the population and workers against the hazards of ionizing radiation

    International Nuclear Information System (INIS)

    1992-01-01

    This Royal Order replaces certain provisions of the General Regulations for protection of the population and workers against the hazards of ionizing radiations. The new provisions concern the monitoring of radioactivity in the national territory and population dose, as well as monitoring of the population as a whole. The purpose of this amendment is to conform without delay to the Opinion of the Commission of the European Communities; the amendment concerns mainly the monitoring of doses received by the population and the technical conditions for such monitoring. (NEA)

  3. Regulation of Blood Glucose Concentration in Type 1 Diabetics Using Single Order Sliding Mode Control Combined with Fuzzy On-line Tunable Gain, a Simulation Study

    OpenAIRE

    Dinani, Soudabeh Taghian; Zekri, Maryam; Kamali, Marzieh

    2015-01-01

    Diabetes is considered as a global affecting disease with an increasing contribution to both mortality rate and cost damage in the society. Therefore, tight control of blood glucose levels has gained significant attention over the decades. This paper proposes a method for blood glucose level regulation in type 1 diabetics. The control strategy is based on combining the fuzzy logic theory and single order sliding mode control (SOSMC) to improve the properties of sliding mode control method and...

  4. Order for execution of the law concerning regulations of nuclear source materials, nuclear fuel materials and reactors

    International Nuclear Information System (INIS)

    1978-01-01

    Under the above mentioned law this order prescribes the procedures of controls given to the persons who wish to conduct refining and fabricating businesses, to construct and operate reactors, and to use nuclear source materials, nuclear fuel materials and internationally controlled materials. The common controlling principle prescribed is that the permission or authorization necessary for above listed businesses should be applied for at each factory or each place of business. Based on the principle, the order prescribes: the procedures to apply for the authorization of the refining business, the permission of the change thereof, and the permission of the fabricating business and the change, thereof (the 1st chapter); the procedures to apply for the permission of the construction of reactors and of the change of the construction, as well as the procedure to do periodic inspections of reactor facilities (the 2nd chapter); the procedures to apply for the permission to use nuclear fuel materials and to change the use thereof, the submission of the report to use nuclear source materials, as well as the procedure to apply for the permission to use internationally controlled materials. In the 4th chapter the order lists up the items on which the competent Ministers may require reports from the person who carries on the relevant business. (Matsushima, A.)

  5. Self-regulation and the problem of human autonomy: does psychology need choice, self-determination, and will?

    Science.gov (United States)

    Ryan, Richard M; Deci, Edward L

    2006-12-01

    The term autonomy literally refers to regulation by the self. Its opposite, heteronomy, refers to controlled regulation, or regulation that occurs without self-endorsement. At a time when philosophers and economists are increasingly detailing the nature of autonomy and recognizing its social and practical significance, many psychologists are questioning the reality and import of autonomy and closely related phenomena such as will, choice, and freedom. Using the framework of self-determination theory (Ryan & Deci, 2000), we review research concerning the benefits of autonomous versus controlled regulation for goal performance, persistence, affective experience, quality of relationships, and well-being across domains and cultures. We also address some of the controversies and terminological issues surrounding the construct of autonomy, including critiques of autonomy by biological reductionists, cultural relativists, and behaviorists. We conclude that there is a universal and cross-developmental value to autonomous regulation when the construct is understood in an exacting way.

  6. Design of a fractional order PID controller for hydraulic turbine regulating system using chaotic non-dominated sorting genetic algorithm II

    International Nuclear Information System (INIS)

    Chen, Zhihuan; Yuan, Xiaohui; Ji, Bin; Wang, Pengtao; Tian, Hao

    2014-01-01

    Highlights: • Multi-objective optimization based fractional order controller is designed for HTRS. • NSGAII is improved by iterative chaotic map with infinite collapses (ICMIC) operator. • ISE and ITSE are as chosen as objective functions in tuning parameters of HTRS. • FOPID controller outperforms the PID controller under various running conditions. • Trade-off between speed of reference tracking and damping of oscillation are shown. - Abstract: Fractional-order PID (FOPID) controller is a generalization of traditional PID controller using fractional calculus. Compared to the traditional PID controller, in FOPID controller, the order of derivative portion and integral portion is not integer, which provides more flexibility in achieving control objectives. Design stage of such an FOPID controller consists of determining five parameters, i.e. proportional, integral and derivative gains {Kp, Ki, Kd}, and extra integration and differentiation orders {λ,μ}, which has a large difference comparing with the conventional PID tuning rules, thus a suitable optimization algorithm is essential to the parameters tuning of FOPID controller. This paper focuses on the design of the FOPID controller using chaotic non-dominated sorting genetic algorithm II (NSGAII) for hydraulic turbine regulating system (HTRS). The parameters chosen of the FOPID controller is formulated as a multi-objective optimization problem, in which the objective functions are composed by the integral of the squared error (ISE) and integral of the time multiplied squared error (ITSE). The chaotic NSGAII algorithm, which is an incorporation of chaotic behaviors into NSGAII, is used as the optimizer to search true Pareto-front of the FOPID controller and designers can implement each of them based on objective functions priority. The designed chaotic NSGAII based FOPID controller procedure is applied to a HTRS system. A comparison study between the optimum integer order PID controller and optimum

  7. Inferring microRNA regulation of mRNA with partially ordered samples of paired expression data and exogenous prediction algorithms.

    Directory of Open Access Journals (Sweden)

    Brian Godsey

    Full Text Available MicroRNAs (miRs are known to play an important role in mRNA regulation, often by binding to complementary sequences in "target" mRNAs. Recently, several methods have been developed by which existing sequence-based target predictions can be combined with miR and mRNA expression data to infer true miR-mRNA targeting relationships. It has been shown that the combination of these two approaches gives more reliable results than either by itself. While a few such algorithms give excellent results, none fully addresses expression data sets with a natural ordering of the samples. If the samples in an experiment can be ordered or partially ordered by their expected similarity to one another, such as for time-series or studies of development processes, stages, or types, (e.g. cell type, disease, growth, aging, there are unique opportunities to infer miR-mRNA interactions that may be specific to the underlying processes, and existing methods do not exploit this. We propose an algorithm which specifically addresses [partially] ordered expression data and takes advantage of sample similarities based on the ordering structure. This is done within a Bayesian framework which specifies posterior distributions and therefore statistical significance for each model parameter and latent variable. We apply our model to a previously published expression data set of paired miR and mRNA arrays in five partially ordered conditions, with biological replicates, related to multiple myeloma, and we show how considering potential orderings can improve the inference of miR-mRNA interactions, as measured by existing knowledge about the involved transcripts.

  8. 31 March 1992 - Royal Order amending Section 133(1) of the General Regulation on safety at Work concerning protection of workers against the hazards of ionizing radiation

    International Nuclear Information System (INIS)

    1992-01-01

    A Royal Order of 31 March 1992 amends certain provisions of the Regulations on safety at work with respect to protection of workers against the hazards of ionizing radiation, amended in 1990. The purpose of the amendment is to avoid that certain international and national civil servants be hindered in their control duties. The following inspectors are concerned: the International Atomic Energy Agency inspectors; the persons designated as responsible for surveillance under the Euratom Treaty and the Act of 1955 on State security in the nuclear field; the inspectors designated by the Act of 1972 on inspections at work. (NEA)

  9. 5th December 1990 - Royal Order amending the provisions of the General Regulations for protection at work, concerning the protection of workers against the hazards of ionizing radiation

    International Nuclear Information System (INIS)

    1990-01-01

    This Royal Order amending the 1946 General Regulations for the protection of workers against the hazards of ionizing radiation implements on a national level the European Community Directives No. 80/836 Euratom of 15 July 1980 laying down basic safety standards for the health protection of the general public and workers against the hazards of ionizing radiations and No. 84/466 Euratom of 3 September 1984 laying down basic measures for the radiation protection of persons undergoing medical examination or treatment [fr

  10. Does the regulation of the insurance industry have a pernicious effect on innovation by the sector in South Africa?

    Directory of Open Access Journals (Sweden)

    Elton Zingwevu

    2015-07-01

    Full Text Available Financial regulation could be a double edged sword in that despite its major thrust being that to secure the financial sector and bring about financial stability; it might have the unintended consequence of stifling innovation by the sector. We investigate the nexus between financial regulation and innovation by specifically focusing on the insurance industry in South Africa. We demonstrate that there are plethora pieces of legislation that govern the insurance industry in South Africa. As such this has driven the cost of compliance to unsustainable levels thereby curtailing the spending by companies on innovation. We thus would like to caution the policy makers’ that this “heavy-touch” regulatory mode is having a pernicious effect on research and development by the insurance sector. As such we encourage them to embrace the “light-touch” regulatory mode whereby self-regulation and moral suasion are other avenues to be considered.

  11. Does regulation stimulate productivity? The effect of air quality policies on the efficiency of US power plants

    International Nuclear Information System (INIS)

    Fleishman, Rachel; Alexander, Rob; Bretschneider, Stuart; Popp, David

    2009-01-01

    This research examines the effect of air quality regulations on the productivity of US power plants based on both economic and environmental outputs. Using data envelopment analysis (DEA) to estimate an efficiency measure incorporating both economic and environmental outcomes, we look at changes in efficiency in US power plants over an eleven-year time period (1994-2004) during which several different regulations were implemented for the control of nitrogen oxides (NO x ) and sulfur dioxide (SO 2 ). The paper then models how estimated efficiency behaves over time as a function of regulatory changes. Findings suggest mixed effects of regulations on power plant efficiency when pollution abatement and electricity generation are both included as outputs.

  12. When the cat’s away the mice will play" : Does regulation at home affect bank risk-taking abroad?

    NARCIS (Netherlands)

    Ongena, S.; Popov, A.; Udell, G.F.

    2013-01-01

    This paper provides the first empirical evidence that bank regulation is associated with cross-border spillover effects through the lending activities of large multinational banks. We analyze business lending by 155 banks to 9,613 firms in 1,976 different localities across 16 countries. We find that

  13. Self-Regulation and Metacognition in Young Children: Does It Matter if Adults Are Present or Not?

    Science.gov (United States)

    Robson, Sue

    2016-01-01

    This paper brings together two areas of considerable interest to researchers, practitioners and policy makers: young children's developing self-regulation and metacognition, and the impact of adult (practitioner) presence or absence on their behaviour and learning. One hundred and twenty-eight observations of 29 children aged 4-5 years in a…

  14. Does Self-Licensing Benefit Self- Regulation Over Time? An Ecological Momentary Assessment Study of Food Temptations

    NARCIS (Netherlands)

    Prinsen, S.|info:eu-repo/dai/nl/369408217; Evers, C.|info:eu-repo/dai/nl/280594232; Wijngaards, Leoniek; van Vliet, Renee; de Ridder, D.T.D.|info:eu-repo/dai/nl/070706174

    2018-01-01

    Self-licensing, employing reasons to justify indulgence, may help resolve the conflict between immediate temptations and long-term goals in favor of the former. It was hypothesized that this conflict-resolving potential of self-licensing may benefit self-regulation over time. With a momentary

  15. Regulation of Blood Glucose Concentration in Type 1 Diabetics Using Single Order Sliding Mode Control Combined with Fuzzy On-line Tunable Gain, a Simulation Study.

    Science.gov (United States)

    Dinani, Soudabeh Taghian; Zekri, Maryam; Kamali, Marzieh

    2015-01-01

    Diabetes is considered as a global affecting disease with an increasing contribution to both mortality rate and cost damage in the society. Therefore, tight control of blood glucose levels has gained significant attention over the decades. This paper proposes a method for blood glucose level regulation in type 1 diabetics. The control strategy is based on combining the fuzzy logic theory and single order sliding mode control (SOSMC) to improve the properties of sliding mode control method and to alleviate its drawbacks. The aim of the proposed controller that is called SOSMC combined with fuzzy on-line tunable gain is to tune the gain of the controller adaptively. This merit causes a less amount of control effort, which is the rate of insulin delivered to the patient body. As a result, this method can decline the risk of hypoglycemia, a lethal phenomenon in regulating blood glucose level in diabetics caused by a low blood glucose level. Moreover, it attenuates the chattering observed in SOSMC significantly. It is worth noting that in this approach, a mathematical model called minimal model is applied instead of the intravenously infused insulin-blood glucose dynamics. The simulation results demonstrate a good performance of the proposed controller in meal disturbance rejection and robustness against parameter changes. In addition, this method is compared to fuzzy high-order sliding mode control (FHOSMC) and the superiority of the new method compared to FHOSMC is shown in the results.

  16. 20 CFR 1002.33 - Does the employee have to prove that the employer discriminated against him or her in order to be...

    Science.gov (United States)

    2010-04-01

    ... employer discriminated against him or her in order to be eligible for reemployment? 1002.33 Section 1002.33... have to prove that the employer discriminated against him or her in order to be eligible for reemployment? No. The employee is not required to prove that the employer discriminated against him or her...

  17. Regulation

    International Nuclear Information System (INIS)

    Ballereau, P.

    1999-01-01

    The different regulations relative to nuclear energy since the first of January 1999 are given here. Two points deserve to be noticed: the decree of the third august 1999 authorizing the national Agency for the radioactive waste management to install and exploit on the commune of Bures (Meuse) an underground laboratory destined to study the deep geological formations where could be stored the radioactive waste. The second point is about the uranium residues and the waste notion. The judgment of the administrative tribunal of Limoges ( 9. july 1998) forbidding the exploitation of a storage installation of depleted uranium considered as final waste and qualifying it as an industrial waste storage facility has been annulled bu the Court of Appeal. It stipulated that, according to the law number 75663 of the 15. july 1965, no criteria below can be applied to depleted uranium: production residue (possibility of an ulterior enrichment), abandonment of a personal property or simple intention to do it ( future use aimed in the authorization request made in the Prefecture). This judgment has devoted the primacy of the waste notion on this one of final waste. (N.C.)

  18. Does lower birth order amplify the association between high socio-economic status and central adiposity in young adult Filipino males?

    OpenAIRE

    Dahly, Darren L; Adair, Linda S

    2010-01-01

    Objective To test the hypothesis that lower birth order amplifies the positive association between socioeconomic status and central adiposity in young adult males from a lower-income, developing country context. Design The Cebu Longitudinal Health and Nutrition Survey is an ongoing community-based, observational study of a one year birth cohort (1983). Subjects 970 young adult males, mean age 21.5 y (2005). Measurements Central adiposity measured by waist circumference; birth order; perinatal...

  19. Fractional-Order Control of a Nonlinear Time-Delay System: Case Study in Oxygen Regulation in the Heart-Lung Machine

    Directory of Open Access Journals (Sweden)

    S. J. Sadati

    2012-01-01

    Full Text Available A fractional-order controller will be proposed to regulate the inlet oxygen into the heart-lung machine. An analytical approach will be explained to satisfy some requirements together with practical implementation of some restrictions for the first time. Primarily a nonlinear single-input single-output (SISO time-delay model which was obtained previously in the literature is introduced for the oxygen generation process in the heart-lung machine system and we will complete it by adding some new states to control it. Thereafter, the system is linearized using the state feedback linearization approach to find a third-order time-delay dynamics. Consequently classical PID and fractional order controllers are gained to assess the quality of the proposed technique. A set of optimal parameters of those controllers are achieved through the genetic algorithm optimization procedure through minimizing a cost function. Our design method focuses on minimizing some famous performance criterions such as IAE, ISE, and ITSE. In the genetic algorithm, the controller parameters are chosen as a random population. The best relevant values are achieved by reducing the cost function. A time-domain simulation signifies the performance of controller with respect to a traditional optimized PID controller.

  20. Does industry self-regulation protect young people from exposure to alcohol marketing? A review of compliance and complaint studies.

    Science.gov (United States)

    Noel, Jonathan K; Babor, Thomas F

    2017-01-01

    Exposure to alcohol marketing is considered to be potentially harmful to adolescents. In addition to statutory regulation, industry self-regulation is a common way to protect adolescents from alcohol marketing exposures. This paper critically reviews research designed to evaluate the effectiveness of the alcohol industry's compliance procedures to manage complaints when alcohol marketing is considered to have violated a self-regulatory code. Peer-reviewed papers were identified through four literature search engines: PubMed, SCOPUS, PsychINFO and CINAHL. Non-peer-reviewed reports produced by public health agencies, alcohol research centers, non-governmental organizations, government research centers and national industry advertising associations were also included. The search process yielded three peer-reviewed papers, seven non-peer reviewed reports published by academic institutes and non-profit organizations and 20 industry reports. The evidence indicates that the complaint process lacks standardization across countries, industry adjudicators may be trained inadequately or biased and few complaints are upheld against advertisements pre-determined to contain violations of a self-regulatory code. The current alcohol industry marketing complaint process used in a wide variety of countries may be ineffective at removing potentially harmful content from the market-place. The process of determining the validity of complaints employed by most industry groups appears to suffer from serious conflict of interest and procedural weaknesses that could compromise objective adjudication of even well-documented complaints. In our opinion the current system of self-regulation needs major modifications if it is to serve public health objectives, and more systematic evaluations of the complaint process are needed. © 2016 Society for the Study of Addiction.

  1. The Influence of Prosodic Input in the Second Language Classroom: Does It Stimulate Child Acquisition of Word Order and Function Words?

    Science.gov (United States)

    Campfield, Dorota E.; Murphy, Victoria A.

    2017-01-01

    This paper reports on an intervention study with young Polish beginners (mean age: 8 years, 3 months) learning English at school. It seeks to identify whether exposure to rhythmic input improves knowledge of word order and function words. The "prosodic bootstrapping hypothesis", relevant in developmental psycholinguistics, provided the…

  2. Does the Order of Item Difficulty of the Addenbrooke's Cognitive Examination Add Anything to Subdomain Scores in the Clinical Assessment of Dementia?

    Science.gov (United States)

    McGrory, Sarah; Starr, John M; Shenkin, Susan D; Austin, Elizabeth J; Hodges, John R

    2015-01-01

    The Addenbrooke's Cognitive Examination (ACE) is used to measure cognition across a range of domains in dementia. Identifying the order in which cognitive decline occurs across items, and whether this varies between dementia aetiologies could add more information to subdomain scores. ACE-Revised data from 350 patients were split into three groups: Alzheimer's type (n = 131), predominantly frontal (n = 119) and other frontotemporal lobe degenerative disorders (n = 100). Results of factor analysis and Mokken scaling analysis were compared. Principal component analysis revealed one factor for each group. Confirmatory factor analysis found that the one-factor model fit two samples poorly. Mokken analyses revealed different item ordering in terms of difficulty for each group. The different patterns for each diagnostic group could aid in the separation of these different types of dementia.

  3. Does the Order of Item Difficulty of the Addenbrooke's Cognitive Examination Add Anything to Subdomain Scores in the Clinical Assessment of Dementia

    Directory of Open Access Journals (Sweden)

    Sarah McGrory

    2015-04-01

    Full Text Available Background: The Addenbrooke's Cognitive Examination (ACE is used to measure cognition across a range of domains in dementia. Identifying the order in which cognitive decline occurs across items, and whether this varies between dementia aetiologies could add more information to subdomain scores. Method: ACE-Revised data from 350 patients were split into three groups: Alzheimer's type (n = 131, predominantly frontal (n = 119 and other frontotemporal lobe degenerative disorders (n = 100. Results of factor analysis and Mokken scaling analysis were compared. Results: Principal component analysis revealed one factor for each group. Confirmatory factor analysis found that the one-factor model fit two samples poorly. Mokken analyses revealed different item ordering in terms of difficulty for each group. Conclusion: The different patterns for each diagnostic group could aid in the separation of these different types of dementia.

  4. Summary of the Special Analysis of Savannah River Depleted Uranium Trioxide Demonstrating the Before and After Impacts on the DOE Order 435.1 Performance Objective and the Peak Dose

    International Nuclear Information System (INIS)

    Shott, G.J.

    2011-01-01

    This report summarizes the special analysis (SA) of the Savannah River Depleted Uranium Trioxide waste stream (SVRSURANIUM03, Revision 1) demonstrating the before and after impacts of the waste stream to the DOE Order 435.1 performance objective at the disposal facility, and the peak dose. The Nevada Division of Environmental Protection (NDEP) requested this SA and asked the Nevada Site Office (NSO) to run the SA deterministically and assume that all the model conditions remain the same regardless of the length of time to the peak dose. Although the NDEP accepts that DOE Order 435.1 requires a compliance period of 1,000 years, it also requested to know what year, if any, the specific DOE performance objectives will be exceeded. Given the NDEP's requested model conditions, the SA demonstrates the Rn-222 peak dose will occur in about 2 million years and will exceed the performance objective in about 6,000 years. The 0.25 mSv y-1 all-pathway performance objective was not exceeded for the resident scenario after reaching the 4 million year peak dose.

  5. Great Big Hairy Bees! Regulating the European Bumblebee, Bombus Terrestris L. What does it say about the Precautionary Principle?

    Directory of Open Access Journals (Sweden)

    Cameron Alastair Moore

    2012-06-01

    Full Text Available The previous Commonwealth Minister for the Environment, Mr Garrett, recently rejected a request to allow the importation of live bumblebees (Bombus terrestris L. to mainland Australia. New South Wales and Victoria had already listed the introduction of bumblebees as, respectively, a key threatening process and a potentially threatening process. The Commonwealth, however, had previously declined an application to list the introduction of bumblebees as a key threatening process, although its Threatened Species Scientific Committee urged ‘that extreme caution be shown in considering any proposal to introduce this species to the mainland.’ The potential threat from bumblebees would appear to beg the questions posed by the precautionary principle. Would the presence of bumblebees to mainland Australia pose a threat of serious or irreversible environmental damage? Should a lack of full scientific certainty be used as a reason for postponing measures to prevent environmental degradation? This paper considers the role of the precautionary principle in regulatory approaches to the bumblebee. It seeks to establish the application of the precautionary principle to this particular potential environmental threat, including its relationship to the principle of conservation of biological diversity. It concludes that, despite widespread adoption of the precautionary principle in policy, legislation and case law in Australia, its impact on regulating bumblebees has not been consistent.

  6. Cold-water acclimation does not modify whole-body fluid regulation during subsequent cold-water immersion.

    Science.gov (United States)

    Stocks, J M; Patterson, M J; Hyde, D E; Jenkins, A B; Mittleman, K D; Taylor, N A S

    2004-06-01

    We investigated the impact of cold-water acclimation on whole-body fluid regulation using tracer-dilution methods to differentiate between the intracellular and extracellular fluid compartments. Seven euhydrated males [age 24.7 (8.7) years, mass 74.4 (6.4) kg, height 176.8 (7.8) cm, sum of eight skinfolds 107.4 (20.4) mm; mean (SD)] participated in a 14-day cold-water acclimation protocol, with 60-min resting cold-water stress tests [CWST; 18.1 (0.1) degrees C] on days 1, 8 and 15, and 90-min resting cold-water immersions [18.4 (0.4) degrees C] on intervening days. Subjects were immersed to the 4th intercostal space. Intracellular and extracellular fluid compartments, and plasma protein, electrolyte and hormone concentrations were investigated. During the first CWST, the intracellular fluid (5.5%) and plasma volumes were reduced (6.1%), while the interstitial fluid volume was simultaneously expanded (5.4%). This pattern was replicated on days 8 and 15, but did not differ significantly among test days. Acclimation did not produce significant changes in the pre-immersion distribution of total body water, or changes in plasma osmolality, total protein, electrolyte, atrial natriuretic peptide or aldosterone concentrations. Furthermore, a 14-day cold-water acclimation regimen did not elicit significant changes in body-fluid distribution, urine production, or the concentrations of plasma protein, electrolytes or the fluid-regulatory hormones. While acclimation trends were not evident, we have confirmed that fluid from extravascular cells is displaced into the interstitium during acute cold-water immersion, both before and after cold acclimation.

  7. The order of exercise during concurrent training for rehabilitation does not alter acute genetic expression, mitochondrial enzyme activity or improvements in muscle function.

    Directory of Open Access Journals (Sweden)

    Lauren G MacNeil

    Full Text Available Concurrent exercise combines different modes of exercise (e.g., aerobic and resistance into one training protocol, providing stimuli meant to increase muscle strength, aerobic capacity and mass. As disuse is associated with decrements in strength, aerobic capacity and muscle size concurrent training is an attractive modality for rehabilitation. However, interference between the signaling pathways may result in preferential improvements for one of the exercise modes. We recruited 18 young adults (10 ♂, 8 ♀ to determine if order of exercise mode during concurrent training would differentially affect gene expression, protein content and measures of strength and aerobic capacity after 2 weeks of knee-brace induced disuse. Concurrent exercise sessions were performed 3x/week for 6 weeks at gradually increasing intensities either with endurance exercise preceding (END>RES or following (RES>END resistance exercise. Biopsies were collected from the vastus lateralis before, 3 h after the first exercise bout and 48 h after the end of training. Concurrent exercise altered the expression of genes involved in mitochondrial biogenesis (PGC-1α, PRC, PPARγ, hypertrophy (PGC-1α4, REDD2, Rheb and atrophy (MuRF-1, Runx1, increased electron transport chain complex protein content, citrate synthase and mitochondrial cytochrome c oxidase enzyme activity, muscle mass, maximum isometric strength and VO 2peak. However, the order in which exercise was completed (END>RES or RES>END only affected the protein content of mitochondrial complex II subunit. In conclusion, concurrent exercise training is an effective modality for the rehabilitation of the loss of skeletal muscle mass, maximum strength, and peak aerobic capacity resulting from disuse, regardless of the order in which the modes of exercise are performed.

  8. The Effect Of A Provisional Sequestration Order - Does It Impose A Limitation To My Right To Be A Member Of Parliament?

    Directory of Open Access Journals (Sweden)

    Leonie Stander

    2015-12-01

    Full Text Available The question asked in this article is inspired by the recent case of Mr Julius Malema. Why the matter is so important and has enjoyed so much attention, is the fact that it was widely suggested that a final order of sequestration would affect Mr Malema's political career in that it would not be possible for him to continue to serve as Member of Parliament. The question that immediately comes to the fore is whether the provisional order of sequestration would not already result in such an outcome. As stipulated by the Constitution of the Republic of South Africa, 1996, an unrehabilitated insolvent may not become a member of the National Assembly, National Council of Provinces, or a Provincial Legislator. Do the words "unrehabilitated insolvent" also include a person who is under provisional sequestration? The purpose of this article is to investigate the effect of a provisional order of sequestration and the focus will be on the ability of an insolvent to act as a Member of Parliament. The legal position in the South African law will be compared with the legal position in the United States of America – which is, with regard to the insolvency law, recognized as a very successful, modern, progressive and dynamic legal system. Voluminous changes to the American bankruptcy law system, to adapt to current practical situations and the current economic climate, have been effected as recently as in 2005. Brief reference will also be made to the legal position in the United Kingdom, due to South Africa's historical ties with the UK and the reliance in the past on the English insolvency law and the Bankruptcy Act, 1986.

  9. The PorX response regulator of the Porphyromonas gingivalis PorXY two-component system does not directly regulate the Type IX secretion genes but binds the PorL subunit.

    Directory of Open Access Journals (Sweden)

    Maxence S Vincent

    2016-08-01

    Full Text Available The Type IX secretion system (T9SS is a versatile multi-protein complex restricted to bacteria of the Bacteriodetes phylum and responsible for the secretion of surface attachment of diverse proteins that participate to S-layer formation, gliding motility or pathogenesis. The T9SS is poorly characterized but a number of proteins involved in the assembly of the secretion apparatus in the oral pathogen Porphyromonas gingivalis have been identified based on genome substractive analyses. Among these proteins, PorY and PorX encode typical two-component system (TCS sensor and CheY-like response regulator respectively. Although the porX and porY genes do not localize at the same genetic locus, it has been proposed that PorXY form a bona fide TCS. Deletion of the porX in P. gingivalis causes a slight decrease of the expression of a number of other T9SS genes, including sov, porT, porP, porK, porL, porM, porN and porY. Here, we show that PorX and the soluble cytoplasmic domain of PorY interact. Using electrophoretic mobility shift, DNA-protein co-purification and heterologous host expression assays, we showed that PorX does not bind and does not directly regulate expression of the T9SS genes. Finally, we show that PorX interacts with the cytoplasmic domain of PorL, a component of the T9SS membrane core complex and propose that the CheY-like PorX protein might be involved in the dynamics of the T9SS.

  10. The PorX Response Regulator of the Porphyromonas gingivalis PorXY Two-Component System Does Not Directly Regulate the Type IX Secretion Genes but Binds the PorL Subunit

    Science.gov (United States)

    Vincent, Maxence S.; Durand, Eric; Cascales, Eric

    2016-01-01

    The Type IX secretion system (T9SS) is a versatile multi-protein complex restricted to bacteria of the Bacteriodetes phylum and responsible for the secretion or cell surface exposition of diverse proteins that participate to S-layer formation, gliding motility or pathogenesis. The T9SS is poorly characterized but a number of proteins involved in the assembly of the secretion apparatus in the oral pathogen Porphyromonas gingivalis have been identified based on genome substractive analyses. Among these proteins, PorY, and PorX encode typical two-component system (TCS) sensor and CheY-like response regulator respectively. Although the porX and porY genes do not localize at the same genetic locus, it has been proposed that PorXY form a bona fide TCS. Deletion of porX in P. gingivalis causes a slight decrease of the expression of a number of other T9SS genes, including sov, porT, porP, porK, porL, porM, porN, and porY. Here, we show that PorX and the soluble cytoplasmic domain of PorY interact. Using electrophoretic mobility shift, DNA-protein co-purification and heterologous host expression assays, we demonstrate that PorX does not bind T9SS gene promoters and does not directly regulate expression of the T9SS genes. Finally, we show that PorX interacts with the cytoplasmic domain of PorL, a component of the T9SS membrane core complex and propose that the CheY-like PorX protein might be involved in the dynamics of the T9SS. PMID:27630829

  11. Ministerial Order of 16 October 1980 supplementing the Ministerial Order of 16 July 1980 providing for regulation of the treatment by ionizing radiation of foodstuffs for human or animal consumption

    International Nuclear Information System (INIS)

    1980-01-01

    This Order which supplements the Order of 16 July 1980 concerning the same subject adds further foodstuffs to the authorized list, together with the related licensing requirements and technical specifications. (NEA) [fr

  12. Does Naming Therapy Make Ordering in a Restaurant Easier? Dynamics of Co-Occurring Change in Cognitive-Linguistic and Functional Communication Skills in Aphasia

    Science.gov (United States)

    Johnson, Jeffrey P.; Villard, Sarah; Kiran, Swathi

    2017-01-01

    Purpose This study was conducted to investigate the static and dynamic relationships between impairment-level cognitive-linguistic abilities and activity-level functional communication skills in persons with aphasia (PWA). Method In Experiment 1, a battery of standardized assessments was administered to a group of PWA (N = 72) to examine associations between cognitive-linguistic ability and functional communication at a single time point. In Experiment 2, impairment-based treatment was administered to a subset of PWA from Experiment 1 (n = 39) in order to examine associations between change in cognitive-linguistic ability and change in function and associations at a single time point. Results In both experiments, numerous significant associations were found between scores on tests of cognitive-linguistic ability and a test of functional communication at a single time point. In Experiment 2, significant treatment-induced gains were seen on both types of measures in participants with more severe aphasia, yet cognitive-linguistic change scores were not significantly correlated with functional communication change scores. Conclusions At a single time point, cognitive-linguistic and functional communication abilities are associated in PWA. However, although changes on standardized assessments reflecting improvements in both types of skills can occur following an impairment-based therapy, these changes may not be significantly associated with each other. PMID:28196373

  13. Modern requirements of legal regulations for transport in the cities and necessity for making sector strategy in order to harmonize with other modes of transport

    Directory of Open Access Journals (Sweden)

    Aleksandra VASILJ

    2010-01-01

    Full Text Available Crucial problem of transport in the cities, as a source of pollution of the environment, are uncontrolled individual motorization, permanently increasing number of motor vehicles on the roads and streets that expels human primary need for walking.Reduced social area is also loaded with vibrations and increased sound pressure which often exceeds recommended 80 dB/A.Accent is on ecological problems caused by: polluted air, which comes from gas emissions (full of aerosol, metals, dust, soot, smoke, cutting and disappearance of green areas in order to provide space for transport, making huge amount of secondary waste (e. g. tyres, metal, used oil, liquids.To improve present sequences and reduce negative effects in the future it is necessary to take different measures: fiscal, administrative, educational, which will restrict use of individual, particularly car traffic. Same measures should be used to encourage users to use public transportation.Transport in the cities, with all weaknesses and comparative advantages, should be separately analyzed mode of road transport and also be an individual part in strategic documents.The most important questions that such strategy of transport in the cities should include are: regulation, privatization or other more efficient mode of organization in public transport of passengers, as well as urban elements of sustainable development of the urban areas and transport.

  14. "Does anger regulation mediate the discrimination-mental health link among Mexican-origin adolescents? A longitudinal mediation analysis using multilevel modeling": Correction to Park et al. (2016).

    Science.gov (United States)

    2017-02-01

    Reports an error in "Does Anger Regulation Mediate the Discrimination-Mental Health Link Among Mexican-Origin Adolescents? A Longitudinal Mediation Analysis Using Multilevel Modeling" by Irene J. K. Park, Lijuan Wang, David R. Williams and Margarita Alegría ( Developmental Psychology , Advanced Online Publication, Nov 28, 2016, np). In the article, there were several typographical errors in the Recruitment and Procedures section. The percentage of mothers who responded to survey items should have been 99.3%. Additionally, the youths surveyed at T2 and T3 should have been n=246 . Accordingly, the percentage of youths surveyed in T2 and T3 should have been 91.4% and the percentage of mothers surveyed at T2 and T3 should have been 90.7%. Finally, the youths missing at T2 should have been n= 23, and therefore the attrition rate for youth participants should have been 8.6. All versions of this article have been corrected. (The following abstract of the original article appeared in record 2016-57671-001.) Although prior research has consistently documented the association between racial/ethnic discrimination and poor mental health outcomes, the mechanisms that underlie this link are still unclear. The present 3-wave longitudinal study tested the mediating role of anger regulation in the discrimination-mental health link among 269 Mexican-origin adolescents ( M age = 14.1 years, SD = 1.6; 57% girls), 12 to 17 years old. Three competing anger regulation variables were tested as potential mediators: outward anger expression, anger suppression, and anger control. Longitudinal mediation analyses were conducted using multilevel modeling that disaggregated within-person effects from between-person effects. Results indicated that outward anger expression was a significant mediator; anger suppression and anger control were not significant mediators. Within a given individual, greater racial/ethnic discrimination was associated with more frequent outward anger expression. In turn

  15. Royal Order of 11 February 1987 amending the Royal Order of 28 February 1987 laying down General Regulations concerning Protection of the Public and Workers against the Hazards of Ionizing Radiation

    International Nuclear Information System (INIS)

    1987-01-01

    This Order implements European Community legislation on radiation protection. It refers to the 1980 Community Directive (as amended in 1984) and concerns standards for liquid or gaseous radioactive effluent releases to the environment. (NEA) [fr

  16. Royal Order of 21 August 1985 amending the Royal Order of 28 February 1963 enacting General Regulations for Protection of the Population and Workers against the Hazards of Ionizing Radiation

    International Nuclear Information System (INIS)

    1985-01-01

    The amendments to the 1963 Royal Order aim to improve the prior licensing procedure for products containing radioisotopes to be used as unsealed sources in human or veterinary medicine for ''in vivo'' or ''in vitro'' diagnostic purposes and for therapy. They concern, in particular, the preparation of the licensing file, quality control procedures and the laboratories approved to perform such controls. The Ministerial Order of 13th April 1984 which contained similar provisions is revoked. (NEA) [fr

  17. Order of 15 September 1992 concerning the Regulations for the transport of dangerous goods (provisions on road transport and alphabetical list of goods) (Dangerous Goods 1992 No. 1)

    International Nuclear Information System (INIS)

    1992-01-01

    The specific provisions of the 1945 Order concerning the transport of dangerous goods by road have been repealed by this 1992 Order, with few exceptions. The provisions covering both road and other transport by land no longer apply to road transport, except for Appendix 6 which concerns flexible lead and equipment for pumping hydrocarbons. The repealed provisions have been replaced by provisions annexed to the 1992 Order. The Annexes concern materials and their mode of transport, transport equipment and the alphabetical list of materials which include radioactive materials. (NEA)

  18. Avoiding dual regulation of the Civilian Radioactive Waste Management Program

    International Nuclear Information System (INIS)

    Vlahakis, J.G.; Palabrica, R.J.

    1994-01-01

    The Office of Civilian Radioactive Waste Management (RW) has successfully negotiated the issuance of a Department of Energy (DOE) Headquarters Order that provides for exemption of RW from certain DOE directives. This exemption assures precedence of Nuclear Regulatory Commission (NRC) requirements in radiation protection, nuclear safety (including quality assurance), and safeguards and security of nuclear materials. This Order is necessary to avoid the unwarranted cost and potential confusion resulting from dual regulation of RW facilities and activities by DOE and NRC. Development of this Order involved a systematic review of applicable DOE directives and NRC requirements to identify potential overlaps and duplication when applied to the RW program. Following this review and extensive negotiations with appropriate DOE organizations responsible for directives development, this Order was issued as HQ 1321.1 on December 22, 1993

  19. Benefits from flywheel energy storage for area regulation in California - demonstration results : a study for the DOE Energy Storage Systems program.

    Energy Technology Data Exchange (ETDEWEB)

    Eyer, James M. (Distributed Utility Associates, Livermore, CA)

    2009-10-01

    This report documents a high-level analysis of the benefit and cost for flywheel energy storage used to provide area regulation for the electricity supply and transmission system in California. Area regulation is an 'ancillary service' needed for a reliable and stable regional electricity grid. The analysis was based on results from a demonstration, in California, of flywheel energy storage developed by Beacon Power Corporation (the system's manufacturer). Demonstrated was flywheel storage systems ability to provide 'rapid-response' regulation. Flywheel storage output can be varied much more rapidly than the output from conventional regulation sources, making flywheels more attractive than conventional regulation resources. The performance of the flywheel storage system demonstrated was generally consistent with requirements for a possible new class of regulation resources - 'rapid-response' energy-storage-based regulation - in California. In short, it was demonstrated that Beacon Power Corporation's flywheel system follows a rapidly changing control signal (the ACE, which changes every four seconds). Based on the results and on expected plant cost and performance, the Beacon Power flywheel storage system has a good chance of being a financially viable regulation resource. Results indicate a benefit/cost ratio of 1.5 to 1.8 using what may be somewhat conservative assumptions. A benefit/cost ratio of one indicates that, based on the financial assumptions used, the investment's financial returns just meet the investors target.

  20. Order of blood draw

    DEFF Research Database (Denmark)

    Cornes, Michael; van Dongen-Lases, Edmée; Grankvist, Kjell

    2017-01-01

    does occur if order of draw is not followed during blood collection and when performing venipuncture under less than ideal circumstances, thus putting patient safety at risk. Moreover, given that order of draw is not difficult to follow and knowing that ideal phlebotomy conditions and protocols...... Medicine Working Group for the Preanalytical Phase (EFLM WG-PRE) provides an overview and summary of the literature with regards to order of draw in venous blood collection. Given the evidence presented in this article, the EFLM WG-PRE herein concludes that a significant frequency of sample contamination...

  1. 7 CFR 1206.13 - Order.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... INFORMATION Mango Promotion, Research, and Information Order Definitions § 1206.13 Order. Order means an order..., research, and information regarding agricultural commodities authorized under the Act. ...

  2. Does Anger Regulation Mediate the Discrimination-Mental Health Link among Mexican-Origin Adolescents? A Longitudinal Mediation Analysis Using Multilevel Modeling

    Science.gov (United States)

    Park, Irene J. K.; Wang, Lijuan; Williams, David R.; Alegría, Margarita

    2017-01-01

    Although prior research has consistently documented the association between racial/ethnic discrimination and poor mental health outcomes, the mechanisms that underlie this link are still unclear. The present 3-wave longitudinal study tested the mediating role of anger regulation in the discrimination-mental health link among 269 Mexican-origin…

  3. Neuro Emotional Literacy Program: Does Teaching the Function of Affect and Affect Regulation Strategies Improve Affect Management and Well-Being?

    Science.gov (United States)

    Patten, Kathryn E.; Campbell, Stephen R.

    2016-01-01

    Although research on Emotion Regulation (ER) is developing at a rapid rate, much of it lacks a clear theoretical framework and most focuses on a narrow set of ER strategies. This work presents the details of a pilot project, the Neuro Emotional Literacy Program (NELP), designed for parents and based on the Somatic Appraisal Model of Affect (SAMA).…

  4. Soft Regulators, though judges

    NARCIS (Netherlands)

    de Geest, G.G.A.; Dari Mattiacci, G.

    Judges have a tendency to be more demanding than regulators. In the United States, a majority of the courts has adopted the rule that the unexcused violation of a statutory standard is negligence per se. However, the converse does not hold: compliance with regulation does not relieve the injurer of

  5. DOE standard: Radiological control

    Energy Technology Data Exchange (ETDEWEB)

    1999-07-01

    The Department of Energy (DOE) has developed this Standard to assist line managers in meeting their responsibilities for implementing occupational radiological control programs. DOE has established regulatory requirements for occupational radiation protection in Title 10 of the Code of Federal Regulations, Part 835 (10 CFR 835), ``Occupational Radiation Protection``. Failure to comply with these requirements may lead to appropriate enforcement actions as authorized under the Price Anderson Act Amendments (PAAA). While this Standard does not establish requirements, it does restate, paraphrase, or cite many (but not all) of the requirements of 10 CFR 835 and related documents (e.g., occupational safety and health, hazardous materials transportation, and environmental protection standards). Because of the wide range of activities undertaken by DOE and the varying requirements affecting these activities, DOE does not believe that it would be practical or useful to identify and reproduce the entire range of health and safety requirements in this Standard and therefore has not done so. In all cases, DOE cautions the user to review any underlying regulatory and contractual requirements and the primary guidance documents in their original context to ensure that the site program is adequate to ensure continuing compliance with the applicable requirements. To assist its operating entities in achieving and maintaining compliance with the requirements of 10 CFR 835, DOE has established its primary regulatory guidance in the DOE G 441.1 series of Guides. This Standard supplements the DOE G 441.1 series of Guides and serves as a secondary source of guidance for achieving compliance with 10 CFR 835.

  6. DOE standard: Radiological control

    International Nuclear Information System (INIS)

    1999-07-01

    The Department of Energy (DOE) has developed this Standard to assist line managers in meeting their responsibilities for implementing occupational radiological control programs. DOE has established regulatory requirements for occupational radiation protection in Title 10 of the Code of Federal Regulations, Part 835 (10 CFR 835), ''Occupational Radiation Protection''. Failure to comply with these requirements may lead to appropriate enforcement actions as authorized under the Price Anderson Act Amendments (PAAA). While this Standard does not establish requirements, it does restate, paraphrase, or cite many (but not all) of the requirements of 10 CFR 835 and related documents (e.g., occupational safety and health, hazardous materials transportation, and environmental protection standards). Because of the wide range of activities undertaken by DOE and the varying requirements affecting these activities, DOE does not believe that it would be practical or useful to identify and reproduce the entire range of health and safety requirements in this Standard and therefore has not done so. In all cases, DOE cautions the user to review any underlying regulatory and contractual requirements and the primary guidance documents in their original context to ensure that the site program is adequate to ensure continuing compliance with the applicable requirements. To assist its operating entities in achieving and maintaining compliance with the requirements of 10 CFR 835, DOE has established its primary regulatory guidance in the DOE G 441.1 series of Guides. This Standard supplements the DOE G 441.1 series of Guides and serves as a secondary source of guidance for achieving compliance with 10 CFR 835

  7. Transnational Normative Orders

    DEFF Research Database (Denmark)

    Kjaer, Poul F.

    2013-01-01

    No weakening, but rather an expansion, of statehood can be observed in the contemporary world. This does not, on the other hand, imply that extensive forms of constitutional ordering do not exist outside the realm of states. Instead, the evolution of world society has been characterized by a prot......No weakening, but rather an expansion, of statehood can be observed in the contemporary world. This does not, on the other hand, imply that extensive forms of constitutional ordering do not exist outside the realm of states. Instead, the evolution of world society has been characterized...... as represented by the constitutional subject. Third, constitutionalism denotes the institutionalization of a double function, in the form of a principle-based and legally fortified striving toward universal inclusion, providing a sense of direction in time through an articulated form of constitutional...

  8. Transnational Normative Orders

    DEFF Research Database (Denmark)

    Kjær, Poul F.

    2017-01-01

    No weakening, but rather an expansion, of statehood can be observed in the contemporary world. This does not, on the other hand, imply that extensive forms of constitutional ordering do not exist outside the realm of states. Instead, the evolution of world society has been characterized by a prot......No weakening, but rather an expansion, of statehood can be observed in the contemporary world. This does not, on the other hand, imply that extensive forms of constitutional ordering do not exist outside the realm of states. Instead, the evolution of world society has been characterized...... as represented by the constitutional subject. Third, constitutionalism denotes the institutionalization of a double function, in the form of a principle-based and legally fortified striving toward universal inclusion, providing a sense of direction in time through an articulated form of constitutional...

  9. 16 July 1985: Royal Order amending the Royal Order of 24 April 1964 on approval of a certain type of apparatus containing radioactive substances, made in implementation of Section 3.1.d/2 of the Royal Order of 28 February 1963 enacting General Regulations for Protection of the Population and Workers against the Hazards of Ionizing Radiation

    International Nuclear Information System (INIS)

    1985-01-01

    The amendments made by this Order mainly concern additional information to be supplied in the context of the approval procedure for certain types of devices containing radioactive substances which are in current use. (NEA) [fr

  10. Plain packaging and indirect expropriation of trademark rights under BITs: does FCTC help to establish a right to regulate tobacco products?

    Science.gov (United States)

    Lo, Chang-Fa

    2012-12-01

    Recently the giant tobacco company Philip Morris served its notice to launch an investor-to-state dispute settlement proceeding against the Australian Government for its introduction of plain packaging requirements on tobacco products. It is an important event in the field of intellectual property, investment and international health law. The fundamental questions involved are whether the restriction of trademark rights as a result of the plain packaging requirement is a compensable indirect expropriation under BITs or whether it falls within the scope of government's right to regulate and thus become not compensable. This paper is of the view that the requirement of plain packaging will deprive the essential value or core function of trademark rights and thus constitutes an indirect expropriation under BITs. However, such indirect expropriation meets the public interest requirement and the necessity requirement. The paper further argues that sovereign States have an inherent right to regulate domestic economic activities. Since the pain packaging requirements provided in the FCTC Guidelines are expected to protect the value of human lives and health, the protected values clearly outweigh the affected commercial interests of tobacco companies. Also the justification for host States to adopt a plain packaging policy is strong. Thus, the interpreters of BITs need to pay higher respect to the host State's sovereign power concerning its right to regulate tobacco products for a legitimate purpose. The conclusion of the paper is that the host States should enjoy a defense of the right to regulate to refuse compensation. The author believes that this is the only reasonable conclusion to avoid possible conflicts between different treaty systems (BITs and the FCTC) and between different legal systems and fields (trademark law, investment law and international health law).

  11. Issues facing the management of radioactively contaminated lead within the DOE system

    International Nuclear Information System (INIS)

    Gilmore, M.C.; Kent, S.H.

    1993-01-01

    The purpose of this paper is to discuss and evaluate the issues that managing and operating contractors in the US DOE system should consider that are associated with management of radioactively contaminated elemental lead. There are many instances where DOE contaminated lead fall within Resource Conservation and Recovery Act (RCRA) regulation. In light of the Federal Facilities Compliance Act (FFCA), it is becoming increasingly important for additional regulatory options to be explored in order to facilitate proper treatment, storage and disposal of RCRA regulated lead. Various DOE facilities have initiated processes to reuse or recycle contaminated lead. Technologies such as melt-refining, surface blasting, and electromigration are being explored. One or more of these technologies may be the key to reducing contaminated lead inventories in the DOE system. Many DOE facilities are finding that these efforts need to have stringent regulatory evaluation since some alternatives have proven to be environmentally desirable but not economically feasible

  12. DOE Fire Protection Handbook, Volume I

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-08-01

    The Department of Energy (DOE) Fire Protection Program is delineated in a number of source documents including; the Code of Federal Regulations (CFR), DOE Policy Statements and Orders, DOE and national consensus standards (such as those promulgated by the National Fire Protection Association), and supplementary guidance, This Handbook is intended to bring together in one location as much of this material as possible to facilitate understanding and ease of use. The applicability of any of these directives to individual Maintenance and Operating Contractors or to given facilities and operations is governed by existing contracts. Questions regarding applicability should be directed to the DOE Authority Having Jurisdiction for fire safety. The information provided within includes copies of those DOE directives that are directly applicable to the implementation of a comprehensive fire protection program. They are delineated in the Table of Contents. The items marked with an asterisk (*) are included on the disks in WordPerfect 5.1 format, with the filename noted below. The items marked with double asterisks are provided as hard copies as well as on the disk. For those using MAC disks, the files are in Wordperfect 2.1 for MAC.

  13. Nuclear energy: Environmental issues at DOE's nuclear defense facilities

    International Nuclear Information System (INIS)

    1986-01-01

    GAO's review of nine Department of Energy defense facilities identified a number of significant environmental issues: (1) eight facilities have groundwater contaminated with radioactive and/or hazardous substances to high levels; (2) six facilities have soil contamination in unexpected areas, including offsite locations; (3) four facilities are not in full compliance with the Clean Water Act; and (4) all nine facilities are significantly changing their waste disposal practices to obtain a permit under the Resource Conservation and Recovery Act. GAO is recommending that DOE develop and overall groundwater and soil protection strategy that would provide a better perspective on the environmental risks and impacts associated with operating DOE's nuclear defense facilities. GAO also recommends that DOE allow outside independent inspections of the disposal practices used for any waste DOE self-regulates and revise its order governing the management of hazardous and mixed waste

  14. Aperiodic order

    CERN Document Server

    Grimm, Uwe

    2017-01-01

    Quasicrystals are non-periodic solids that were discovered in 1982 by Dan Shechtman, Nobel Prize Laureate in Chemistry 2011. The mathematics that underlies this discovery or that proceeded from it, known as the theory of Aperiodic Order, is the subject of this comprehensive multi-volume series. This second volume begins to develop the theory in more depth. A collection of leading experts, among them Robert V. Moody, cover various aspects of crystallography, generalising appropriately from the classical case to the setting of aperiodically ordered structures. A strong focus is placed upon almost periodicity, a central concept of crystallography that captures the coherent repetition of local motifs or patterns, and its close links to Fourier analysis. The book opens with a foreword by Jeffrey C. Lagarias on the wider mathematical perspective and closes with an epilogue on the emergence of quasicrystals, written by Peter Kramer, one of the founders of the field.

  15. Arteriolar hyalinosis does not interfere with the local veno-arteriolar reflex regulation of subcutaneous blood flow in insulin-dependent diabetic patients

    DEFF Research Database (Denmark)

    Kastrup, J; Nørgaard, T; Parving, H H

    1987-01-01

    The function of the local nervous veno-arteriolar reflex regulation of blood flow in subcutaneous tissue of the lower leg was studied in diabetic patients. The material comprised 11 long-term insulin-dependent diabetic (IDDM) patients with retinopathy and nephropathy and eight short-term IDDM...... patients without retinopathy or nephropathy and 11 non-diabetic subjects. The diabetic patients had no or a slight to moderate degree of peripheral autonomic and sensoric neuropathy. Blood flow was measured by the local 133Xe wash-out technique. Blood flow was determined before, during and after...

  16. Yes-associated protein and WW-containing transcription regulator 1 regulate the expression of sex-determining genes in Sertoli cells, but their inactivation does not cause sex reversal.

    Science.gov (United States)

    Levasseur, Adrien; Paquet, Marilène; Boerboom, Derek; Boyer, Alexandre

    2017-07-01

    Yes-associated protein (YAP) and WW-containing transcription regulator 1 (WWTR1) are two functionally redundant transcriptional regulators that are downstream effectors of the Hippo signaling pathway, and that act as major regulators of cell growth and differentiation. To elucidate their role in Sertoli cells, primary Sertoli cell culture from Yapflox/flox; Wwtr1flox/flox animals were infected with a Cre recombinase-expressing adenovirus. Concomitant inactivation of Yap and Wwtr1 resulted in a decrease in the mRNA levels of the male sex differentiation genes Dhh, Dmrt1, Sox9, and Wt1, whereas those of genes involved in female differentiation (Wnt4, Rspo1, and Foxl2) were induced. SOX9, FOXL2, and WNT4 proteins were regulated in the same manner as their mRNAs in response to loss of YAP and WWTR1. To further characterize the role of YAP and WWTR1 in Sertoli cells, we generated a mouse model (Yapflox/flox; Wwtr1flox/flox; Amhcre/+) in which Yap and Wwtr1 were conditionally deleted in Sertoli cells. An increase in the number of apoptotic cells was observed in the seminiferous tubules of 4 dpp mutant mice, leading to a reduction in testis weights and a decrease in the number of Sertoli cells in adult animals. Gene expression analyses of testes from 4 dpp Yapflox/flox; Wwtr1flox/flox; Amhcre/+ mice showed that Sertoli cell differentiation is initially altered, as Dhh, Dmrt1, and Sox9 mRNA levels were downregulated, whereas Wnt4 mRNA levels were increased. However, expression of these genes was not changed in older animals. Together, these results suggest a novel role of the Hippo signaling pathway in the mechanisms of sex differentiation. © The Authors 2017. Published by Oxford University Press on behalf of Society for the Study of Reproduction. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  17. Does environmental regulation affect energy efficiency in China's thermal power generation? Empirical evidence from a slacks-based DEA model

    International Nuclear Information System (INIS)

    Bi, Gong-Bing; Song, Wen; Zhou, P.; Liang, Liang

    2014-01-01

    Data envelopment analysis (DEA) has gained much popularity in performance measurement of power industry. This paper presents a slack-based measure approach to investigating the relationship between fossil fuel consumption and the environmental regulation of China's thermal power generation. We first calculate the total-factor energy efficiency without considering environmental constraints. An environmental performance indicator is proposed through decomposing the total-factor energy efficiency. The proposed approach is then employed to examine whether environmental regulation affects the energy efficiency of China's thermal power generation. We find that the environmental efficiency plays a significant role in affecting energy performance of China's thermal generation sector. Decreasing the discharge of major pollutants can improve both energy performance and environmental efficiency. Besides, we also have three main findings: (1) The energy efficiency and environmental efficiency were relatively low. (2) The energy and environmental efficiency scores show great variations among provinces. (3) Both energy efficiency and environmental efficiency are of obvious geographical characteristics. According to our findings, we suggest some policy implications. - Highlights: • We assess the energy efficiency and the environmental efficiency of China's thermal power generation simultaneously. • The energy efficiency and the environmental efficiency were relatively low during 2007–2009. • The energy efficiency and environmental efficiency show obvious geographic characters. • The environmental performance of a DMU plays a decisive role in the energy performance

  18. VHL genetic alteration in CCRCC does not determine de-regulation of HIF, CAIX, hnRNP A2/B1 and osteopontin.

    LENUS (Irish Health Repository)

    Nyhan, Michelle J

    2012-01-31

    BACKGROUND: von Hippel-Lindau (VHL) tumour suppressor gene inactivation is associated with clear cell renal cell carcinoma (CCRCC) development. The VHL protein (pVHL) has been proposed to regulate the expression of several proteins including Hypoxia Inducible Factor-alpha (HIF-alpha), carbonic anhydrase (CA)IX, heterogeneous nuclear ribonucleoprotein (hnRNP) A2\\/B1 and osteopontin. pVHL has been characterized in vitro, however, clinical studies are limited. We evaluated the impact of VHL genetic alterations on the expression of several pVHL protein targets in paired normal and tumor tissue. METHODS: The VHL gene was sequenced in 23 CCRCC patients and VHL transcript levels were evaluated by real-time RT-PCR. Expression of pVHL\\'s protein targets were determined by Western blotting in 17 paired patient samples. RESULTS: VHL genetic alterations were identified in 43.5% (10\\/23) of CCRCCs. HIF-1alpha, HIF-2alpha and CAIX were up-regulated in 88.2% (15\\/17), 100% (17\\/17) and 88.2% (15\\/17) of tumors respectively and their expression is independent of VHL status. hnRNP A2\\/B1 and osteopontin expression was variable in CCRCCs and had no association with VHL genetic status. CONCLUSION: As expression of these proposed pVHL targets can be achieved independently of VHL mutation (and possibly by hypoxia alone), these data suggests that other pVHL targets may be more crucial in renal carcinogenesis.

  19. The down-regulation of the mitogenic fibrinogen receptor (MFR) in serum-containing medium does not occur in defined medium.

    Science.gov (United States)

    Levesque, J P; Hatzfeld, A; Domart, I; Hatzfeld, J

    1990-02-01

    Normal human hemopoietic cells such as early bone marrow progenitors, or lymphoma-derived cell lines such as Raji or JM cells, possess a low-affinity receptor specific for fibrinogen. This receptor triggers a mitogenic effect. It differs from the glycoprotein IIb-IIIa which is involved in fibrinogen-induced platelet aggregation. We demonstrate here that this mitogenic fibrinogen receptor (MFR) can be internalized or reexpressed, depending on culture conditions. Internalization was temperature-dependent. At 37 degrees C in the presence of cycloheximide or actinomycin D, the half-life of cell surface MFRs was 2 h, independent of receptor occupancy. Binding of fibrinogen to the MFR resulted in a down-regulation which was fibrinogen dose-dependent. This occurred in serum-supplemented medium but not in defined medium supplemented with fatty acids. Reexpression of MFRs could be induced in 28 to 42 h by serum removal. The down-regulation of mitogenic receptors in plasma or serum could explain why normal cells do not proliferate in the peripheral blood.

  20. 77 FR 8095 - Technical Corrections to Commission Regulations

    Science.gov (United States)

    2012-02-14

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission 18 CFR Part 2 [Docket No. RM11-30-000; Order No. 756] Technical Corrections to Commission Regulations Issued February 8, 2012. AGENCY: Federal Energy Regulatory Commission, DOE. ACTION: Final rule: correcting amendment. SUMMARY: This document adds...

  1. Market, Regulation, Market, Regulation

    DEFF Research Database (Denmark)

    Frankel, Christian; Galland, Jean-Pierre

    2015-01-01

    barriers to trade in Europe, realized the free movement of products by organizing progressively several orders of markets and regulation. Based on historical and institutional documents, on technical publications, and on interviews, this article relates how the European Commission and the Member States had......This paper focuses on the European Regulatory system which was settled both for opening the Single Market for products and ensuring the consumers' safety. It claims that the New Approach and Standardization, and the Global Approach to conformity assessment, which suppressed the last technical...... alternatively recourse to markets and to regulations, at the three main levels of the New Approach Directives implementation. The article focuses also more specifically on the Medical Devices sector, not only because this New Approach sector has long been controversial in Europe, and has recently been concerned...

  2. Considering an Affect Regulation Framework for Examining the Association Between Body Dissatisfaction and Positive Body Image in Black Older Adolescent Females: Does Body Mass Index Matter?

    Science.gov (United States)

    Butler-Ajibade, Phoebe; Robinson, Seronda A.

    2014-01-01

    The present study provided an initial evaluation of an affect regulation model describing the association between body dissatisfaction and two contemporary measures of positive body image among 247 Black college-bound older adolescent females. We further tested whether possessing a higher body mass index (BMI) would strengthen these associations. Self-reported height and weight were used to calculate BMI. Respondents also completed a culturally-sensitive figure rating scale along with assessments of body appreciation and body image flexibility. Results indicated a robust positive association between the two measures of positive body image; BMI was the strongest predictor of both body appreciation and body image flexibility with body size discrepancy (current minus ideal) contributing incremental variance to both models tested. Implications for improving our understanding of the association between positive and negative body image and bolstering positive body image to promote health-protective behaviors among Black young women at this developmental juncture are discussed. PMID:25079011

  3. DOE 2012 occupational radiation exposure

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-10-01

    The U.S. Department of Energy (DOE) Office of Analysis within the Office of Health, Safety and Security (HSS) publishes the annual DOE Occupational Radiation Exposure Report to provide an overview of the status of radiation protection practices at DOE (including the National Nuclear Security Administration [NNSA]). The DOE 2012 Occupational Radiation Exposure Report provides an evaluation of DOE-wide performance regarding compliance with Title 10, Code of Federal Regulations (C.F.R.), Part 835, Occupational Radiation Protection dose limits and as low as reasonably achievable (ALARA) process requirements. In addition, the report provides data to DOE organizations responsible for developing policies for protection of individuals from the adverse health effects of radiation. The report provides a summary and an analysis of occupational radiation exposure information from the monitoring of individuals involved in DOE activities. Over the past 5-year period, the occupational radiation exposure information is analyzed in terms of aggregate data, dose to individuals, and dose by site.

  4. DOE 2011 occupational radiation exposure

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2012-12-01

    The U.S. Department of Energy (DOE) Office of Analysis within the Office of Health, Safety and Security (HSS) publishes the annual DOE Occupational Radiation Exposure Report to provide an overview of the status of radiation protection practices at DOE (including the National Nuclear Security Administration [NNSA]). The DOE 2011 Occupational Radiation Exposure Report provides an evaluation of DOE-wide performance regarding compliance with Title 10, Code of Federal Regulations (C.F.R.), Part 835, Occupational Radiation Protection dose limits and as low as reasonably achievable (ALARA) process requirements. In addition, the report provides data to DOE organizations responsible for developing policies for protection of individuals from the adverse health effects of radiation. The report provides a summary and an analysis of occupational radiation exposure information from the monitoring of individuals involved in DOE activities. The occupational radiation exposure information is analyzed in terms of aggregate data, dose to individuals, and dose by site over the past five years.

  5. Culture and emotion regulation.

    Science.gov (United States)

    Ford, Brett Q; Mauss, Iris B

    2015-06-01

    While anthropological research has long emphasized cultural differences in whether emotions are viewed as beneficial versus harmful, psychological science has only recently begun to systematically examine those differences and their implications for emotion regulation and well-being. Underscoring the pervasive role of culture in people's emotions, we summarize research that has examined links between culture, emotion regulation, and well-being. Specifically, we focus on two questions. First, how does culture lead individuals to regulate their emotions? And second, how does culture modulate the link between emotion regulation and well-being? We finish by suggesting directions for future research to advance the study of culture and emotion regulation.

  6. Fisheries regulation

    DEFF Research Database (Denmark)

    Jensen, Frank; Frost, Hans Staby; Abildtrup, Jens

    2017-01-01

    Economists normally claim that a stock externality arises within fisheries because each individual fisherman does not take the effect on stock size into account when making harvest decisions. Due to the stock externality, it is commonly argued that fisheries regulation is necessary, but regulatory...... decisions are complicated by a tremendous amount of uncertainty and asymmetric information. This paper provides an overview of selected parts of the literature on the regulation of fisheries under uncertainty and asymmetric information, and possible areas for future research are identified. Specifically...

  7. Closeout technical report for DOE award number DE-FG02-97ER62332 [Nitrogen budget under elevated CO{sub 2} levels: regulation by absorption and assimilation

    Energy Technology Data Exchange (ETDEWEB)

    BassiriRad, Hormoz; Gutschick, Vincent

    2001-10-01

    This entire project was conducted between 1995 and 1999, during which two postdocs and numerous undergraduate students received training in research. Furthermore, the funds from this grant contributed either totally or partially to the publication of 14 refereed journal articles. The focus of this research was to investigate plant nitrogen budget under elevated CO{sub 2} concentration. Of particular interest were the following: (1) Does elevated CO{sub 2} increase root carbohydrate availability? (2) Does such an enhancement increase kinetics of root nitrogen acquisition? (3) Does the effect on kinetics differ between NH{sub 4}{sup +} and NO{sub 3}{sup -}? (4) If there are interspecific differences in (1)-(3), could those variations lead to changes in community composition? This report shows that, although root carbohydrate availability often increases in response to elevated CO{sub 2}, such an increase is neither necessary nor directly related to changes in root N uptake kinetics . The data also show that, depending on species, the effects of elevated CO{sub 2} on root nitrogen uptake kinetics ranges from down regulation to no changes to up regulation. Furthermore, the effects on NH{sub 4}{sup +} are not always similar to the effects on NO{sub 3}{sup -}. Perhaps the most critical finding is the fact that in many instances a change in root N uptake kinetics alone does not provide a reliable prediction of plant N acquisition in response to elevated CO{sub 2}. It is shown that a better examination of whether plant N uptake responds to CO{sub 2} level and whether such a response can be scaled up to community level processes would require integration of knowledge of other root system characteristics. For example, it is well established that mycorrhizal fungi are important regulators of plant N uptake. The data suggest that, while elevated CO{sub 2} affects root N uptake capacity, this effect is highly dependent on the type and level of the mycorrhizal infection. Another

  8. Does anger regulation mediate the discrimination-mental health link among Mexican-origin adolescents? A longitudinal mediation analysis using multilevel modeling.

    Science.gov (United States)

    Park, Irene J K; Wang, Lijuan; Williams, David R; Alegría, Margarita

    2017-02-01

    [Correction Notice: An Erratum for this article was reported in Vol 53(2) of Developmental Psychology (see record 2017-04475-001). In the article, there were several typographical errors in the Recruitment and Procedures section. The percentage of mothers who responded to survey items should have been 99.3%. Additionally, the youths surveyed at T2 and T3 should have been n 246. Accordingly, the percentage of youths surveyed in T2 and T3 should have been 91.4% and the percentage of mothers surveyed at T2 and T3 should have been 90.7%. Finally, the youths missing at T2 should have been n 23, and therefore the attrition rate for youth participants should have been 8.6. All versions of this article have been corrected.] Although prior research has consistently documented the association between racial/ethnic discrimination and poor mental health outcomes, the mechanisms that underlie this link are still unclear. The present 3-wave longitudinal study tested the mediating role of anger regulation in the discrimination-mental health link among 269 Mexican-origin adolescents ( M age = 14.1 years, SD = 1.6; 57% girls), 12 to 17 years old. Three competing anger regulation variables were tested as potential mediators: outward anger expression, anger suppression, and anger control. Longitudinal mediation analyses were conducted using multilevel modeling that disaggregated within-person effects from between-person effects. Results indicated that outward anger expression was a significant mediator; anger suppression and anger control were not significant mediators. Within a given individual, greater racial/ethnic discrimination was associated with more frequent outward anger expression. In turn, more frequent outward anger expression was associated with higher levels of anxiety and depression at a given time point. Gender, age, and nativity status were not significant moderators of the hypothesized mediation models. By identifying outward anger expression as an explanatory

  9. Does the conceptus of the viviparous lizard Barisia imbricata imbricata participates in the regulation of progesterone production and the control of luteolysis?

    Science.gov (United States)

    Martínez-Torres, Martín; Salcedo-Álvarez, Martha; Alvarez-Rodríguez, Carmen; Cárdenas-León, Mario; Luis, Juana; Moreno-Fierros, Leticia

    2014-08-01

    It is generally accepted that progesterone is necessary to maintain gestation; however, the mechanisms that control the production of this steroid remain unknown. The corpus luteum has been assigned a central role in the maintenance of gestation based on its capacity to produce progesterone. A pseudopregnancy model was performed in a viviparous lizard, Barisia imbricata imbricata, to determine whether the absence of embryos would affect the pattern of progesterone production or the corpus luteum histology. Blood samples were obtained prior to ovulation and at 8, 16, and 24 weeks after ovulation (pseudopregnant and pregnant lizards), as well as one day after parturition (pregnant lizards) or 32 weeks after ovulation (pseudopregnant lizards). The corpus luteum was surgically removed one day after blood samples were obtained. Blood aliquots from nongravid females were obtained at similar timepoints. We found a significant reduction in plasma progesterone concentrations at 24 and 32 weeks post-ovulation in pseudopregnant lizards compared with those observed at similar times in intact pregnant lizards, whereas the progesterone levels in non-gestant lizards remained significantly lower than in either pseudopregnant or pregnant lizards. Moreover, we observed that the histological appearance of the corpus luteum from pseudogestational females (obtained 24 and 32 weeks post-ovulation) differed from the corpora lutea from lizards in late gestation and intact parturient lizards. These observations suggest that the conceptus participates in the regulation of progesterone production in late gestation and also in luteolysis control. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. Considering an affect regulation framework for examining the association between body dissatisfaction and positive body image in Black older adolescent females: does body mass index matter?

    Science.gov (United States)

    Webb, Jennifer B; Butler-Ajibade, Phoebe; Robinson, Seronda A

    2014-09-01

    The present study provided an initial evaluation of an affect regulation model describing the association between body dissatisfaction and two contemporary measures of positive body image among 247 Black college-bound older adolescent females. We further tested whether possessing a higher body mass index (BMI) would strengthen these associations. Self-reported height and weight were used to calculate BMI. Respondents also completed a culturally-sensitive figure rating scale along with assessments of body appreciation and body image flexibility. Results indicated a robust positive association between the two measures of positive body image; BMI was the strongest predictor of both body appreciation and body image flexibility with body size discrepancy (current minus ideal) contributing incremental variance to both models tested. Implications for improving our understanding of the association between positive and negative body image and bolstering positive body image to promote health-protective behaviors among Black young women at this developmental juncture are discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. Regulated underground storage tanks

    International Nuclear Information System (INIS)

    1992-06-01

    This guidance package is designed to assist DOE Field operations by providing thorough guidance on the underground storage tank (UST) regulations. [40 CFR 280]. The guidance uses tables, flowcharts, and checklists to provide a ''roadmap'' for DOE staff who are responsible for supervising UST operations. This package is tailored to address the issues facing DOE facilities. DOE staff should use this guidance as: An overview of the regulations for UST installation and operation; a comprehensive step-by-step guidance for the process of owning and operating an UST, from installation to closure; and a quick, ready-reference guide for any specific topic concerning UST ownership or operation

  12. DOE management

    International Nuclear Information System (INIS)

    Rezendes, V.S.

    1991-07-01

    This paper reports that GAO, as well as the Department of Energy's Inspector General, have pointed out the need for major improvement in the University of California's management of the three DOE laboratories-Lawrence Livermore, Los Alamos, and Lawrence Berkeley- and DOE oversight of that management effort. GAO found problems with University of California controls over laboratory operations, such as managing property, protecting classified documents, and ensuring that subcontractors are not subject to foreign influence, which might lead to transfers of nuclear technology to foreign influence, which might lead to transfers of nuclear technology or materials to foreign countries. In addition, clauses in the University of California contracts hamper DOE's ability to effectively manage the laboratories. DOE has addressed many of the specific problems that GAO identified and has tried to improve overall contract management. Negotiations with the University of California to extend the laboratory contracts will present another opportunity for DOE to take a firm stance on the need for management improvements. Having appropriate procedures and resources in place would also help DOE carry out its administration of contracts

  13. C. difficile 630Δerm Spo0A regulates sporulation, but does not contribute to toxin production, by direct high-affinity binding to target DNA.

    Directory of Open Access Journals (Sweden)

    Katharina E Rosenbusch

    Full Text Available Clostridium difficile is a Gram positive, anaerobic bacterium that can form highly resistant endospores. The bacterium is the causative agent of C. difficile infection (CDI, for which the symptoms can range from a mild diarrhea to potentially fatal pseudomembranous colitis and toxic megacolon. Endospore formation in Firmicutes, including C. difficile, is governed by the key regulator for sporulation, Spo0A. In Bacillus subtilis, this transcription factor is also directly or indirectly involved in various other cellular processes. Here, we report that C. difficile Spo0A shows a high degree of similarity to the well characterized B. subtilis protein and recognizes a similar binding sequence. We find that the laboratory strain C. difficile 630Δerm contains an 18bp-duplication near the DNA-binding domain compared to its ancestral strain 630. In vitro binding assays using purified C-terminal DNA binding domain of the C. difficile Spo0A protein demonstrate direct binding to DNA upstream of spo0A and sigH, early sporulation genes and several other putative targets. In vitro binding assays suggest that the gene encoding the major clostridial toxin TcdB may be a direct target of Spo0A, but supernatant derived from a spo0A negative strain was no less toxic towards Vero cells than that obtained from a wild type strain, in contrast to previous reports. These results identify for the first time direct (putative targets of the Spo0A protein in C. difficile and make a positive effect of Spo0A on production of the large clostridial toxins unlikely.

  14. Lack of conventional oxygen-linked proton and anion binding sites does not impair allosteric regulation of oxygen binding in dwarf caiman hemoglobin

    Science.gov (United States)

    Fago, Angela; Malte, Hans; Storz, Jay F.; Gorr, Thomas A.

    2013-01-01

    In contrast to other vertebrate hemoglobins (Hbs) whose high intrinsic O2 affinities are reduced by red cell allosteric effectors (mainly protons, CO2, organic phosphates, and chloride ions), crocodilian Hbs exhibit low sensitivity to organic phosphates and high sensitivity to bicarbonate (HCO3−), which is believed to augment Hb-O2 unloading during diving and postprandial alkaline tides when blood HCO3− levels and metabolic rates increase. Examination of α- and β-globin amino acid sequences of dwarf caiman (Paleosuchus palpebrosus) revealed a unique combination of substitutions at key effector binding sites compared with other vertebrate and crocodilian Hbs: β82Lys→Gln, β143His→Val, and β146His→Tyr. These substitutions delete positive charges and, along with other distinctive changes in residue charge and polarity, may be expected to disrupt allosteric regulation of Hb-O2 affinity. Strikingly, however, P. palpebrosus Hb shows a strong Bohr effect, and marked deoxygenation-linked binding of organic phosphates (ATP and DPG) and CO2 as carbamate (contrasting with HCO3− binding in other crocodilians). Unlike other Hbs, it polymerizes to large complexes in the oxygenated state. The highly unusual properties of P. palpebrosus Hb align with a high content of His residues (potential sites for oxygenation-linked proton binding) and distinctive surface Cys residues that may form intermolecular disulfide bridges upon polymerization. On the basis of its singular properties, P. palpebrosus Hb provides a unique opportunity for studies on structure-function coupling and the evolution of compensatory mechanisms for maintaining tissue O2 delivery in Hbs that lack conventional effector-binding residues. PMID:23720132

  15. Final Report for DOE Grant DE-FG02-03ER25579; Development of High-Order Accurate Interface Tracking Algorithms and Improved Constitutive Models for Problems in Continuum Mechanics with Applications to Jetting

    Energy Technology Data Exchange (ETDEWEB)

    Puckett, Elbridge Gerry [U.C. Davis, Department of Mathematics; Miller, Gregory Hale [.C. Davis, Department of Chemical Engineering

    2012-10-14

    Much of the work conducted under the auspices of DE-FG02-03ER25579 was characterized by an exceptionally close collaboration with researchers at the Lawrence Berkeley National Laboratory (LBNL). For example, Andy Nonaka, one of Professor Miller's graduate students in the Department of Applied Science at U. C. Davis (UCD) wrote his PhD thesis in an area of interest to researchers in the Applied Numerical Algorithms Group (ANAG), which is a part of the National Energy Research Supercomputer Center (NERSC) at LBNL. Dr. Nonaka collaborated closely with these researchers and subsequently published the results of this collaboration jointly with them, one article in a peer reviewed journal article and one paper in the proceedings of a conference. Dr. Nonaka is now a research scientist in the Center for Computational Sciences and Engineering (CCSE), which is also part of the National Energy Research Supercomputer Center (NERSC) at LBNL. This collaboration with researchers at LBNL also included having one of Professor Puckett's graduate students in the Graduate Group in Applied Mathematics (GGAM) at UCD, Sarah Williams, spend the summer working with Dr. Ann Almgren, who is a staff scientist in CCSE. As a result of this visit Sarah decided work on a problem suggested by the head of CCSE, Dr. John Bell, for her PhD thesis. Having finished all of the coursework and examinations required for a PhD, Sarah stayed at LBNL to work on her thesis under the guidance of Dr. Bell. Sarah finished her PhD thesis in June of 2007. Writing a PhD thesis while working at one of the University of California (UC) managed DOE laboratories is long established tradition at UC and Professor Puckett has always encouraged his students to consider doing this. Another one of Professor Puckett's graduate students in the GGAM at UCD, Christopher Algieri, was partially supported with funds from DE-FG02-03ER25579 while he wrote his MS thesis in which he analyzed and extended work originally

  16. Ordering within Moral Orders to Manage Classroom Trouble

    Science.gov (United States)

    Doherty, Catherine; McGregor, Rowena; Shield, Paul

    2016-01-01

    This paper demonstrates how classroom trouble warranting teacher intervention can stem from transgressions in different layers of the complex moral order regulating classroom interactions. The paper builds from Durkheim's treatment of schooling as the institution responsible for the inculcation of a shared moral order, Bernstein's distinction…

  17. Hazardous Substance Release Reporting Under CERCLA, EPCR {section}304 and DOE Emergency Management System (EMS) and DOE Occurrence Reporting Requirements. Environmental Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Traceski, T.T.

    1994-06-01

    Releases of various substances from DOE facilities may be subject to reporting requirements under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) and the Emergency Planning and Community Right-to-Know Act (EPCRA), as well as DOE`s internal ``Occurrence Reporting and Processing of Operations Information`` and the ``Emergency Management System`` (EMS). CERCLA and EPCPA are Federal laws that require immediate reporting of a release of a Hazardous Substance (HS) and an Extremely Hazardous Substance (EHS), respectively, in a Reportable Quantity (RQ) or more within a 24-hour period. This guidance uses a flowchart, supplemental information, and tables to provide an overview of the process to be followed, and more detailed explanations of the actions that must be performed, when chemical releases of HSs, EHSs, pollutants, or contaminants occur at DOE facilities. This guidance should be used in conjunction with, rather than in lieu of, applicable laws, regulations, and DOE Orders. Relevant laws, regulations, and DOE Orders are referenced throughout this guidance.

  18. Dancing with the regulations - Part Deux

    International Nuclear Information System (INIS)

    Nitschke, R.L.

    1995-01-01

    The disposal of low-level radioactive waste (LLW) in the United States has long been subjected to two very similar regulations depending upon the location. Disposal sites located on Department of Energy (DOE) Reservations are subject to DOE Order 5820.2A open-quotes Radioactive Waste Management,close quotes while disposal sites located elsewhere are subject to the Nuclear Regulatory Commission regulation 10 CFR 61 open-quotes Licensing Requirements for Land Disposal of Radioactive Waste.close quotes While life was not necessarily good, there was only one sheet of music to dance to. Recently a new player, named CERCLA (Comprehensive Environmental Response, Compensation, and Liability Act), has ridden into those DOE towns, and for those whose disposal facilities lie within or adjacent to Superfund sites, she has brought along a different drum to dance to. This paper discusses the differences and similarities between the different dance partners and their associated musical scores (i.e., the performance assessment (PA) required by the DOE order and the baseline risk assessment (BRA) required by CERCLA). The paper then provides a brief discussion on the latest dancer to cut in: the Defense Nuclear Facilities Safety Board (DNFSB). This discussion should help to alleviate the confusion while dancing on the LLW disposal regulatory ballroom floor

  19. Dancing with the regulations - Part Deux

    Energy Technology Data Exchange (ETDEWEB)

    Nitschke, R.L. [Lockheed Martin Idaho Technologies, Idaho Falls, ID (United States)

    1995-12-31

    The disposal of low-level radioactive waste (LLW) in the United States has long been subjected to two very similar regulations depending upon the location. Disposal sites located on Department of Energy (DOE) Reservations are subject to DOE Order 5820.2A {open_quotes}Radioactive Waste Management,{close_quotes} while disposal sites located elsewhere are subject to the Nuclear Regulatory Commission regulation 10 CFR 61 {open_quotes}Licensing Requirements for Land Disposal of Radioactive Waste.{close_quotes} While life was not necessarily good, there was only one sheet of music to dance to. Recently a new player, named CERCLA (Comprehensive Environmental Response, Compensation, and Liability Act), has ridden into those DOE towns, and for those whose disposal facilities lie within or adjacent to Superfund sites, she has brought along a different drum to dance to. This paper discusses the differences and similarities between the different dance partners and their associated musical scores (i.e., the performance assessment (PA) required by the DOE order and the baseline risk assessment (BRA) required by CERCLA). The paper then provides a brief discussion on the latest dancer to cut in: the Defense Nuclear Facilities Safety Board (DNFSB). This discussion should help to alleviate the confusion while dancing on the LLW disposal regulatory ballroom floor.

  20. Regulative environmental policy. Regulative Umweltpolitik

    Energy Technology Data Exchange (ETDEWEB)

    Goerlitz, A; Voigt, R [Universitaet der Bundeswehr Muenchen, Neubiberg (Germany, F.R.). Fakultaet fuer Sozialwissenschaften; eds.

    1991-01-01

    Regulative policy means those governmental attempts to steer the course of things which can fall back on a certain repertoire of instruments for actions in order to warrant the causal and temporal connection between the making available and the employment of means. The fact that environmental protection needs regulative policy is substantiated by the thesis that the market has failed; consequently only government can manage the public goods 'environment' in a suitable way, and it is a matter of fact that environmental protection at present is operated preferably via regulative policy. The problems of regulative enviromental policy are manifold. Its implementation often miscarries because of limited administrative resources on the one hand - making sufficient control impossible for instance -, and because of poor quality regulative instruments on the other hand. One way out would be to increase the efficiency of regulative policy by sophisticating judicial techniques. Other ways out point to the executing level and aim at improving implementation strategies or are concerned with post-regulative law. The latter refers to a new legal quality which demonstrates itself already in corporatistical crisis regulation or in induction programs such as pollution limits. A final way out favours deregulation strategies which includes the introduction of environmental levies or the allocation of environmental licences. An interdisciplinary discourse is to find out what would happen if these ways were taken. Pointers to solutions from varying scientific disciplines resulting from this discourse are to be found in this volume. (orig./HSCH).

  1. Regulation Development for Drinking Water Contaminants

    Science.gov (United States)

    To explain what process and information underlies regulations including how the Safe Drinking Water Act applies to regulation development i.e. how does the drinking water law translate into regulations.

  2. Gender Orders Unbound?

    DEFF Research Database (Denmark)

    During the last thirty years, the modernisation of gender relations has been dynamic and comprehensive, shaped by the conflicting forces of globalisation as well as women's movements around the world. As the patterns of segregation and discrimination of the classical industrial gender order erode......, new complexities and contentions in gender relations emerge at various sites such as politics, work and families. The main aim of the book is to trace formal as well as informal gender contracts as they emerge in everyday life and also in new norms and regulations set by state and enterprises. Core...... issues are the chances and the barriers for equality and new forms of gender reciprocity and solidarity....

  3. States consider suit if DOE refuses spent fuel

    International Nuclear Information System (INIS)

    Zeyher, A.

    1994-01-01

    Michigan, Florida, and Minnesota were joined by Wisconsin on April 21 in the Nuclear Waste Strategy Coalition (NWSC), a group of utilities, state regulators, and state attorneys general that have banded together to decide what to do about the Department of Energy's apparent intention to renege on its obligation to begin taking title to spent nuclear fuel by January 31, 1998. According to Ronald Russell, a commissioner on the Michigan Public Service Commission and cofounder of the NWSC, another six states have expressed interest in joining the coalition. open-quotes We're looking at encouraging the DOE to step up to its legal responsibility to take nuclear spent fuel by 1998,close quotes Russell said. The objectives of the coalition include asking the DOE to support privatization of nuclear storage, to review the management of the final repository program in order to make it more efficient, and to identify legislative changes that the DOE might feel are necessary for it to accomplish its charge. The NWSC is also considering filing a lawsuit in response to the DOE's open-quotes anticipatory breach of an executory contract.close quotes The NWSC and others feel that the Nuclear Waste Policy Act of 1982 and the related standard contracts between the DOE and the utilities form a legal contract for the DOE to take the spent fuel on the agreed upon date

  4. 77 FR 4887 - DOE Patent Licensing Regulations

    Science.gov (United States)

    2012-02-01

    ... administered by the National Nuclear Security Administration (NNSA) for NNSA facilities. The NNSA Deputy... issue a Family Policymaking Assessment for any rule or policy that may affect family well being. This rule will have no impact on family, the autonomy or integrity of the family as an institution...

  5. DOE standard: Firearms safety

    International Nuclear Information System (INIS)

    1996-02-01

    Information in this document is applicable to all DOE facilities, elements, and contractors engaged in work that requires the use of firearms as provided by law or contract. The standard in this document provides principles and practices for implementing a safe and effective firearms safety program for protective forces and for non-security use of firearms. This document describes acceptable interpretations and methods for meeting Order requirements

  6. DOE standard: Firearms safety

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-01

    Information in this document is applicable to all DOE facilities, elements, and contractors engaged in work that requires the use of firearms as provided by law or contract. The standard in this document provides principles and practices for implementing a safe and effective firearms safety program for protective forces and for non-security use of firearms. This document describes acceptable interpretations and methods for meeting Order requirements.

  7. DOE wants Hanford change

    International Nuclear Information System (INIS)

    Anon.

    1994-01-01

    Nine months ago, Energy Secretary Hazel O'Leary promised local officials running the agency's huge Hanford, Washington, weapon complex more control in directing its projected $57-billion waste cleanup. Earlier this month, she returned to the site for a follow-on open-quotes summit,close quotes this time ordering teamwork with contractors, regulators and local activities

  8. Order Aggressiveness and Order Book Dynamics

    OpenAIRE

    Anthony D. Hall; Nikolaus Hautsch

    2004-01-01

    In this paper, we study the determinants of order aggressiveness and traders' order submission strategy in an open limit order book market. Using order book data from the Australian Stock Exchange, we model traders' aggressiveness in market trading, limit order trading as well as in order cancellations on both sides of the market using a six-dimensional autoregressive intensity model. The information revealed by the open order book plays an important role in explaining the degree of order agg...

  9. Notification of the French Energy Regulator the 5 june 2001 on the order fixing the purchase conditions of the electricity produced by installations using the wind energy; Avis de la commission de regulation de l'electricite en date du 5 juin 2001 sur l'arrete fixant les conditions d'achat de l'electricite produite par les installations utilisant l'energie mecanique du vent

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-06-01

    This document presents the economic analysis realized by the CRE, French Energy Regulator, to give its opinion on the order concerning the purchase conditions of the electricity produced by wind energy. An operating costs comparison with other energies forms shows that the proposed tariff will lead to a significant increase of the electric power. In consequence, the CRE is opposed to this order. (A.L.B.)

  10. Radiation exposures for DOE and DOE contractor employees, 1989

    International Nuclear Information System (INIS)

    Smith, M.H.; Eschbach, P.A.; Harty, R.; Millet, W.H.; Scholes, V.A.

    1992-12-01

    All US Department of Energy (DOE) and DOE contractors, are required to submit occupational radiation exposure records to a central depository. In 1989, data were required to be submitted for all employees who were required to be monitored in accordance with DOE Order 5480.11 and for all visitors who had a positive exposure. The data required included the external penetrating whole-body dose equivalent, the shallow dose equivalent, and a summary of internal depositions of radioactive material above specified limits. Data regarding the exposed individuals included the individual's age, sex, and occupational category. This report is a summary of the external penetrating whole-body dose equivalents and shallow dose equivalents reported by DOE and DOE contractors for the calendar year 1989. A total of 90,882 DOE and DOE contractor employees were reported to have been monitored for whole-body ionizing radiation exposure during 1989. This represents 53.6% of all DOE and DOE contractor employees and is an increase (4.3 %) from the number of monitored employees for 1988. In addition to the employees, 12,643 visitors were monitored

  11. Licensed reactor nuclear safety criteria applicable to DOE reactors

    International Nuclear Information System (INIS)

    1991-04-01

    The Department of Energy (DOE) Order DOE 5480.6, Safety of Department of Energy-Owned Nuclear Reactors, establishes reactor safety requirements to assure that reactors are sited, designed, constructed, modified, operated, maintained, and decommissioned in a manner that adequately protects health and safety and is in accordance with uniform standards, guides, and codes which are consistent with those applied to comparable licensed reactors. This document identifies nuclear safety criteria applied to NRC [Nuclear Regulatory Commission] licensed reactors. The titles of the chapters and sections of USNRC Regulatory Guide 1.70, Standard Format and Content of Safety Analysis Reports for Nuclear Power Plants, Rev. 3, are used as the format for compiling the NRC criteria applied to the various areas of nuclear safety addressed in a safety analysis report for a nuclear reactor. In each section the criteria are compiled in four groups: (1) Code of Federal Regulations, (2) US NRC Regulatory Guides, SRP Branch Technical Positions and Appendices, (3) Codes and Standards, and (4) Supplemental Information. The degree of application of these criteria to a DOE-owned reactor, consistent with their application to comparable licensed reactors, must be determined by the DOE and DOE contractor

  12. Order aggressiveness and order book dynamics

    DEFF Research Database (Denmark)

    Hall, Anthony D.; Hautsch, Nikolaus

    2006-01-01

    In this paper, we study the determinants of order aggressiveness and traders’ order submission strategy in an open limit order book market. Applying an order classification scheme, we model the most aggressive market orders, limit orders as well as cancellations on both sides of the market...... employing a six-dimensional autoregressive conditional intensity model. Using order book data from the Australian Stock Exchange, we find that market depth, the queued volume, the bid-ask spread, recent volatility, as well as recent changes in both the order flow and the price play an important role...... in explaining the determinants of order aggressiveness. Overall, our empirical results broadly confirm theoretical predictions on limit order book trading. However, we also find evidence for behavior that can be attributed to particular liquidity and volatility effects...

  13. DOE 2013 occupational radiation exposure

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2014-11-01

    The Office of Analysis within the U.S. Department of Energy (DOE) Office of Environment, Health, Safety and Security (EHSS) publishes the annual DOE Occupational Radiation Exposure Report to provide an overview of the status of radiation protection practices at DOE (including the National Nuclear Security Administration [NNSA]). The DOE 2013 Occupational Radiation Exposure Report provides an evaluation of DOE-wide performance regarding compliance with Title 10, Code of Federal Regulations (C.F.R.), Part 835, Occupational Radiation Protection dose limits and as low as reasonably achievable (ALARA) process requirements. In addition, the report provides data to DOE organizations responsible for developing policies for protection of individuals from the adverse health effects of radiation. The report provides a summary and an analysis of occupational radiation exposure information from the monitoring of individuals involved in DOE activities. Over the past five-year period, the occupational radiation exposure information has been analyzed in terms of aggregate data, dose to individuals, and dose by site.

  14. Issues related to EM management of DOE spent nuclear fuel

    International Nuclear Information System (INIS)

    Abbott, D.G.; Abashian, M.S.; Chakraborti, S.; Roberson, K.; Meloin, J.M.

    1993-07-01

    This document is a summary of the important issues involved in managing spent nuclear fuel (SNF) owned by the Department of Energy (DOE). Issues related to civilian SNF activities are not discussed. DOE-owned SNF is stored primarily at the Hanford Site, Idaho National Engineering Laboratory (INEL), Savannah River Site (SRS), Oak Ridge National Laboratory (ORNL), and West Valley Demonstration Project. Smaller quantities of SNF are stored at Brookhaven National Laboratory, Sandia National Laboratories, and Los Alamos National Laboratory (LANL). There is a wide variety of fuel types, including both low and high enrichment fuels from weapons production, DOE reactors, research and development programs, naval programs, and universities. Most fuel is stored in pools associated with reactor or reprocessing facilities. Smaller quantities are in dry storage. Physical conditions of the fuel range from excellent to poor or severely damaged. An issue is defined as an important question that must be answered or decision that must be made on a topic or subject relevant to achieving the complimentary objectives of (a) storing SNF in compliance with applicable regulations and orders until it can be disposed, and (b) safely disposing of DOE's SNF. The purpose of this document is to define the issues; no recommendations are made on resolutions. As DOE's national SNF management program is implemented, a system of issues identification, documentation, tracking, and resolution will be implemented. This document is an initial effort at issues identification. The first section of this document is an overview of issues that are common to several or all DOE facilities that manage SNF. The common issues are organized according to specific aspects of spent fuel management. This is followed by discussions of management issues that apply specifically to individual DOE facilities. The last section provides literature references

  15. 10 CFR 820.33 - Default order.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Default order. 820.33 Section 820.33 Energy DEPARTMENT OF ENERGY PROCEDURAL RULES FOR DOE NUCLEAR ACTIVITIES Enforcement Process § 820.33 Default order. (a) Default. The Presiding Officer, upon motion by a party or the filing of a Notice of Intent to issue a...

  16. 19 CFR 4.74 - Transportation orders.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Transportation orders. 4.74 Section 4.74 Customs... VESSELS IN FOREIGN AND DOMESTIC TRADES Foreign Clearances § 4.74 Transportation orders. Clearance shall... voyage would be in violation of any provision of any transportation order, regulation, or restriction...

  17. Regulated prices: for how long more?

    International Nuclear Information System (INIS)

    Pauron, M.

    2008-01-01

    Does a government has to intervene in a liberalize market? Between the purchasing power of consumers, the rise of raw materials price and the opening of markets, each announcement by the French government of an increase of the tariffs of Gaz de France (GDF: the historical French gas utility) irritates the ones and the others: the consumer considers it as another attack to its purchasing power, while the gas operators, GDF and its competitors, consider that the gas prices remain below the market prices, does not reflect the real increase of costs, and disturbs the good operation of the competitive market. This paper put the question of what must be the position of a government in a de-regulated energy market in order to implement sustainable economic measures and protect the low-income consumers. (J.S.)

  18. Implementation guide for use with suspect/counterfeit items: Requirements of DOE O 440.1, worker protection management; 10 CFR 830.120; and DOE 5700.6C, quality assurance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    Department of Energy (DOE) Order (O) 440.1, Worker Protection Management For DOE Federal and Contractors Employees, [7] sets forth requirements for DOE and its contractors to implement suspect and counterfeit items (S/CI) controls as part of the quality assurance (QA) programs required by 10 Code of Federal Regulations (CFR) 830.120 [8] or DOE 5700.6C, Quality Assurance [9]. DOE G-830.120, Implementation Guide for Use with 10 CFR Part 830.120, Quality Assurance, [10] provides additional guidance on establishing and implementing effective QA processes to control S/CIs. DOE O 232.1, Occurrence Reporting and Processing of Operations, [11] specifies requirements for reporting S/CIs under the DOE Occurrence Reporting and Processing System (ORPS). DOE promulgated the requirements and guidance to control or eliminate the hazards posed by S/CIs, which can lead to unexpected equipment failures and undue risks to the DOE mission, the environment, and personnel. This Guide is a compendium of information contained in the referenced DOE directives and other documents concerning S/CI controls. It incorporates, updates, and supersedes earlier guidance issued in Plan for the Suspect/Counterfeit Products Issue in the Department of Energy, dated October 1993, [4] and in memoranda issued by Defense Programs (DP) [12-16] and other DOE program offices. This guidance was developed to strengthen the procurement process, identify and eliminate S/CIs, and improve the reporting of S/CIs. The information in this Guide, when implemented by DOE and its contractors, will satisfy the S/CI requirements contained in the referenced DOE directives.

  19. Implementation guide for use with suspect/counterfeit items: Requirements of DOE O 440.1, worker protection management; 10 CFR 830.120; and DOE 5700.6C, quality assurance

    International Nuclear Information System (INIS)

    1997-06-01

    Department of Energy (DOE) Order (O) 440.1, Worker Protection Management For DOE Federal and Contractors Employees, [7] sets forth requirements for DOE and its contractors to implement suspect and counterfeit items (S/CI) controls as part of the quality assurance (QA) programs required by 10 Code of Federal Regulations (CFR) 830.120 [8] or DOE 5700.6C, Quality Assurance [9]. DOE G-830.120, Implementation Guide for Use with 10 CFR Part 830.120, Quality Assurance, [10] provides additional guidance on establishing and implementing effective QA processes to control S/CIs. DOE O 232.1, Occurrence Reporting and Processing of Operations, [11] specifies requirements for reporting S/CIs under the DOE Occurrence Reporting and Processing System (ORPS). DOE promulgated the requirements and guidance to control or eliminate the hazards posed by S/CIs, which can lead to unexpected equipment failures and undue risks to the DOE mission, the environment, and personnel. This Guide is a compendium of information contained in the referenced DOE directives and other documents concerning S/CI controls. It incorporates, updates, and supersedes earlier guidance issued in Plan for the Suspect/Counterfeit Products Issue in the Department of Energy, dated October 1993, [4] and in memoranda issued by Defense Programs (DP) [12-16] and other DOE program offices. This guidance was developed to strengthen the procurement process, identify and eliminate S/CIs, and improve the reporting of S/CIs. The information in this Guide, when implemented by DOE and its contractors, will satisfy the S/CI requirements contained in the referenced DOE directives

  20. Education, Birth Order, and Family Size

    OpenAIRE

    Bagger, Jesper; Birchenall, Javier A.; Mansour, Hani; Urzua, Sergio

    2013-01-01

    We introduce a general framework to analyze the trade-off between education and family size. Our framework incorporates parental preferences for birth order and delivers theoretically consistent birth order and family size effects on children's educational attainment. We develop an empirical strategy to identify these effects. We show that the coefficient on family size in a regression of educational attainment on birth order and family size does not identify the family size effect as defined...

  1. 78 FR 61953 - Order Denying Export Privileges

    Science.gov (United States)

    2013-10-08

    ... counsel, Gormley has indicated that he does not intend to contest BIS's decision to deny his export..., selling, delivering, storing, disposing of, forwarding, transporting, financing, or otherwise servicing in... Regulations that has been or will be exported from the United States, including financing or other support...

  2. Royal Order of 28 February 1963 embodying the general Regulations for the Protection of the Population against the Hazards of Ionizing Radiations, as amended by Royal Orders of 17 May 1966, 22 May 1967, 23 December 1970 and 23 May 1972

    International Nuclear Information System (INIS)

    1972-06-01

    This Royal Order embodying successive amendments lays down all the provisions to be complied with to protect workers and the population against the hazards of ionizing radiations. It applies to nuclear trade, including transport, to facilities containing substances emitting ionizing radiations and to operations involving handling, storage and disposal of radioactive substances or waste. It lays down the maximum permissible dose for the different categories of workers and the population and classifies nuclear establishments into four classes in descending order of importance, according to the activity of the radionuclides contained therein. Radiation protection measures are provided for all classes, as are medical check-ups of workers by approved doctors. Special commissions are set up to supervise compliance with the radiation protection measures. The Order also lists the activities requiring licences and the procedures for obtaining them. Finally, as regards maximum permissible dose rates, the Order is supplemented by schedules giving the numerical values of radionuclides. (NEA) [fr

  3. Certified higher-order recursive path ordering

    NARCIS (Netherlands)

    Koprowski, A.; Pfenning, F.

    2006-01-01

    The paper reports on a formalization of a proof of wellfoundedness of the higher-order recursive path ordering (HORPO) in the proof checker Coq. The development is axiom-free and fully constructive. Three substantive parts that could be used also in other developments are the formalizations of the

  4. 7 CFR 29.6005 - Case (order).

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Case (order). 29.6005 Section 29.6005 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... content. ...

  5. 78 FR 45497 - Final Decision and Order

    Science.gov (United States)

    2013-07-29

    ...)) (Act).\\6\\ In accordance with Section 766.7 of the Regulations, BIS moved for the issuance of an Order... Docket Clerk, United States Coast Guard, ALJ Dockering Center, 40 S. Gay Street, Room 414, Baltimore, MD...

  6. Environmental regulations and their effects on the nuclear regulator

    International Nuclear Information System (INIS)

    McManus, J.G.

    1994-01-01

    Environmental regulations are discussed from the point of view of the Canadian Atomic Energy Control Board (AECB). The AECB's mission includes the environment, namely 'to ensure that the use of nuclear energy in Canada does not pose any undue risk to health, safety, security or the environment'. The regulatory process was governed by the Atomic Energy Control Act, which at the time of the conference was outdated and due for replacement by a new version, and by the Environmental Assessment and Review Process Guidelines Order, which was due to be replaced by the Canadian Environmental Assessment Act, still not in force at the time of the conference. Through court decisions, the Guidelines Order had effectively acquired statutory authority. Public hearings and review can result in some considerable delay to the approval of a project, yet the AECB has no choice but to ensure that the requirements of the Guidelines Order are fulfilled. Collaboration between the federal and provincial governments is very evident in Saskatchewan. Of six mining projects being considered by the AECB, five were being reviewed by a joint federal provincial panel. For the future, it was hoped that the new Atomic Energy Control Act would increase fines and the powers of inspectors, require financial guarantees for decommissioning, regularize cooperation with the provinces, and empower the AECB to hold hearings that could effectively substitute for those prescribed by the Canadian Environmental Assessment Act

  7. Wetting transitions: First order or second order

    International Nuclear Information System (INIS)

    Teletzke, G.F.; Scriven, L.E.; Davis, H.T.

    1982-01-01

    A generalization of Sullivan's recently proposed theory of the equilibrium contact angle, the angle at which a fluid interface meets a solid surface, is investigated. The generalized theory admits either a first-order or second-order transition from a nonzero contact angle to perfect wetting as a critical point is approached, in contrast to Sullivan's original theory, which predicts only a second-order transition. The predictions of this computationally convenient theory are in qualitative agreement with a more rigorous theory to be presented in a future publication

  8. DOE Waste Treatability Group Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Kirkpatrick, T.D.

    1995-01-01

    This guidance presents a method and definitions for aggregating U.S. Department of Energy (DOE) waste into streams and treatability groups based on characteristic parameters that influence waste management technology needs. Adaptable to all DOE waste types (i.e., radioactive waste, hazardous waste, mixed waste, sanitary waste), the guidance establishes categories and definitions that reflect variations within the radiological, matrix (e.g., bulk physical/chemical form), and regulated contaminant characteristics of DOE waste. Beginning at the waste container level, the guidance presents a logical approach to implementing the characteristic parameter categories as part of the basis for defining waste streams and as the sole basis for assigning streams to treatability groups. Implementation of this guidance at each DOE site will facilitate the development of technically defined, site-specific waste stream data sets to support waste management planning and reporting activities. Consistent implementation at all of the sites will enable aggregation of the site-specific waste stream data sets into comparable national data sets to support these activities at a DOE complex-wide level.

  9. DOE Waste Treatability Group Guidance

    International Nuclear Information System (INIS)

    Kirkpatrick, T.D.

    1995-01-01

    This guidance presents a method and definitions for aggregating U.S. Department of Energy (DOE) waste into streams and treatability groups based on characteristic parameters that influence waste management technology needs. Adaptable to all DOE waste types (i.e., radioactive waste, hazardous waste, mixed waste, sanitary waste), the guidance establishes categories and definitions that reflect variations within the radiological, matrix (e.g., bulk physical/chemical form), and regulated contaminant characteristics of DOE waste. Beginning at the waste container level, the guidance presents a logical approach to implementing the characteristic parameter categories as part of the basis for defining waste streams and as the sole basis for assigning streams to treatability groups. Implementation of this guidance at each DOE site will facilitate the development of technically defined, site-specific waste stream data sets to support waste management planning and reporting activities. Consistent implementation at all of the sites will enable aggregation of the site-specific waste stream data sets into comparable national data sets to support these activities at a DOE complex-wide level

  10. Does competition influence safety?

    International Nuclear Information System (INIS)

    Pamme, H.

    2000-01-01

    Competition in the deregulated electricity market does not leave nuclear power plants unaffected. Operators seek to run their plants at maximum availability and with optimized cost structures so that specific generating costs are minimized. The 'costs of safety', with their fixed-cost character, are elements of this cost structure. Hence the question whether safety is going to suffer under the cost pressure on the market. The study shows that the process of economic optimization does not permit cost minimization for its own sake in the area of operating costs which can be influenced by management or are 'avoidable'. The basis of assessment rather must be potential risks which could entail losses of availability. Prophylactic investments made in order to avoid losses of availability to a large extent also imply unchanged or even higher levels of safety. Economic viability and safety thus are closely correlated. Competition in a deregulated marekt so far has not done any direct harm to plant safety. An even more efficient use of scarce funds and, hopefully, a tolerable political environment should allow the safety level of nuclear power plants to be upheld, and safety culture to be maintained, also in the future. (orig.) [de

  11. DOE regulation of mixed waste. Hearing before the Subcommittee on Energy Conservation and Power and the Subcommittee on Commerce, Transportation, and Tourism of the Committee on Energy and Commerce, House of Representatives, Ninety-Ninth Congress, Second Session on H. R. 2009 and H. R. 2593, April 10, 1986

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    Testimony by representatives of the Environmental Protection Agency, citizen environmental organizations, DOE, and universities on the Mixed Hazardous Waste Amendment Act of 1985 (H.R. 2009) and the Military Radioactive Emissions Control Act of 1985 (H.R. 2593) focused on safety aspects of mixed wastes at DOE facilities from the point of view of the general public and the implications for tourism and recreation in affected areas. H.R. 2593 calls for standards and continuous independent monitoring, while H.R. 2009 ensures that wastes the Solid Waste Management Act covers solid wastes containing radioactive material. The testimony covered definitions and interpretations by byproduct material and the problems associated with self-regulation. The testimony of the 10 witnesses follows the text of the two bills.

  12. DOE regulation of mixed waste. Hearing before the Subcommittee on Energy Conservation and Power and the Subcommittee on Commerce, Transportation, and Tourism of the Committee on Energy and Commerce, House of Representatives, Ninety-Ninth Congress, Second Session on H.R. 2009 and H.R. 2593, April 10, 1986

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    Testimony by representatives of the Environmental Protection Agency, citizen environmental organizations, DOE, and universities on the Mixed Hazardous Waste Amendment Act of 1985 (H.R. 2009) and the Military Radioactive Emissions Control Act of 1985 (H.R. 2593) focused on safety aspects of mixed wastes at DOE facilities from the point of view of the general public and the implications for tourism and recreation in affected areas. H.R. 2593 calls for standards and continuous independent monitoring, while H.R. 2009 ensures that wastes the Solid Waste Management Act covers solid wastes containing radioactive material. The testimony covered definitions and interpretations by byproduct material and the problems associated with self-regulation. The testimony of the 10 witnesses follows the text of the two bills

  13. Regulating the Regulator

    Energy Technology Data Exchange (ETDEWEB)

    1992-08-26

    The article reports on a challenge to the UK electricity regulator to defend his record by the Coalition for Fair Electricity Regulation (COFFER). The challenge centres on whether the obligation for the regional electric companies (REC) to purchase power from the cheapest source is being enforced. This is related to the wider issue of whether the REC's support of combined-cycle gas turbine (CCGT) is economic. COFFER considers that uneconomic gas-fired power plants are being allowed to displace economic coal-fired stations. Aspects discussed include the background to the dispute and the costs of CCGT and coal fired power generation. 1 fig., 1 tab.

  14. Overview of the DOE-EM Packaging Certification Program

    International Nuclear Information System (INIS)

    Feldman, M.R.; Bennett, M.E.; Shuler, J.M.

    2009-01-01

    The U.S. Department of Transportation, in 49 CFR 173.7(d) grants the U.S. Department of Energy (DOE) the power to use 'packagings made by or under the direction of the U.S. Department of Energy... for the transportation of Class 7 materials when evaluated, approved and certified by the Department of Energy against packaging standards equivalent to those specified in 10 CFR part 71'. Via DOE Order 460.1B, DOE has established the DOE Packaging Certification Program (PCP) within the Department of Environmental Management for purposes including the certification of radioactive materials packages for DOE use. This paper will provide an overview of the programs and activities currently undertaken by the PCP in support of the safe transport of radioactive materials, including technical review of Safety Analysis Reports for Packaging, development of guidance documents and training courses, a quality assurance audit and field assessment program, database and docket management, and testing and test methodology development. The paper will also highlight the various organizations currently utilized by the PCP to meet the requirements of DOE O 460.1B, as well as some creative and effective methods that are being used to meet program objectives. The DOE Package Certification Program's primary function is to perform technical reviews of SARPs in support of the packaging certification process to ensure that the maximum protection is afforded to the public, all federal regulations are met, and the process is as time-effective and cost-effective as possible. Five additional specific functions are also supported by the PCP: development of guidance documents, training courses, a QA audit and field assessment program, database and docket management, and testing methods development. Each of these functions individually contributes to the overall mission of the PCP as defined in DOE O 460.1B. Taken as a whole, these functions represent a robust program to ensure the safety of workers

  15. Material control and accountability orders

    International Nuclear Information System (INIS)

    Jewell, D.L.

    1988-01-01

    The Department of Energy's (DOE) Material Control and Accountability (MC and A) Orders were revised during this past year. The primary focus of the revision process was to eliminate any policy gaps that existed between current orders and the standards and criteria and to examine current policy where questions of completeness or effectiveness may be of concern. The MC and A Subtask Group identified the following three major areas for change: (1) the need to expand the graded safeguards concept; (2) the need to provide for defense in depth; and (3) the need to include system performance requirements. Operational and cost impacts were of primary consideration in these changes. The subtask group accomplished its goal as directed and within the required time frames. The revision process benefitted tremendously from the earlier works of the numerous standards and criteria committees and the Operation Cerberus Committees

  16. First order electroweak phase transition

    International Nuclear Information System (INIS)

    Buchmueller, W.; Fodor, Z.

    1993-01-01

    In this work, the authors have studied the phase transition in the SU(2)gauge theory at finite temperature. The authors' improved perturbative approach does not suffer from the infrared problems appearing in the ordinary loop expansion. The authors have calculated the effective potential up to cubic terms in the couplings. The higher order terms suggest that the method is reliable for Higgs masses smaller than 80 GeV. The authors have obtained a non-vanishing magnetic mass which further weakens the transitions. By use of Langer's theory of metastability, the authors have calculated the nucleation rate for critical bubbles and have discussed some cosmological consequences. For m H <80 GeV the phase transition is first order and proceeds via bubble nucleation and growth. The thin wall approximation is only marginally applicable. Since the phase transition is quite weak SM baryogenesis is unlikely. 8 refs., 5 figs

  17. Large-order perturbation theory

    International Nuclear Information System (INIS)

    Wu, T.T.

    1982-01-01

    The original motivation for studying the asymptotic behavior of the coefficients of perturbation series came from quantum field theory. An overview is given of some of the attempts to understand quantum field theory beyond finite-order perturbation series. At least is the case of the Thirring model and probably in general, the full content of a relativistic quantum field theory cannot be recovered from its perturbation series. This difficulty, however, does not occur in quantum mechanics, and the anharmonic oscillator is used to illustrate the methods used in large-order perturbation theory. Two completely different methods are discussed, the first one using the WKB approximation, and a second one involving the statistical analysis of Feynman diagrams. The first one is well developed and gives detailed information about the desired asymptotic behavior, while the second one is still in its infancy and gives instead information about the distribution of vertices of the Feynman diagrams

  18. DOE Standard: Fire protection design criteria

    International Nuclear Information System (INIS)

    1999-07-01

    The development of this Standard reflects the fact that national consensus standards and other design criteria do not comprehensively or, in some cases, adequately address fire protection issues at DOE facilities. This Standard provides supplemental fire protection guidance applicable to the design and construction of DOE facilities and site features (such as water distribution systems) that are also provided for fire protection. It is intended to be used in conjunction with the applicable building code, National Fire Protection Association (NFPA) Codes and Standards, and any other applicable DOE construction criteria. This Standard replaces certain mandatory fire protection requirements that were formerly in DOE 5480.7A, ''Fire Protection'', and DOE 6430.1A, ''General Design Criteria''. It also contains the fire protection guidelines from two (now canceled) draft standards: ''Glove Box Fire Protection'' and ''Filter Plenum Fire Protection''. (Note: This Standard does not supersede the requirements of DOE 5480.7A and DOE 6430.1A where these DOE Orders are currently applicable under existing contracts.) This Standard, along with the criteria delineated in Section 3, constitutes the basic criteria for satisfying DOE fire and life safety objectives for the design and construction or renovation of DOE facilities

  19. Operational accidents and radiation exposures at DOE facilities. Fiscal year 1978

    International Nuclear Information System (INIS)

    1978-01-01

    Comprehensive safety programs are maintained at DOE facilities in order to protect both personnel and property from accidents. To ensure compliance with safety standards and regulations and maximize effectiveness of the safety programs, an extensive inspection and appraisal program is conducted at the contractor and field office levels by both DOE field and Headquarters safety personnel. When accidents do occur, investigations are conducted to identify causes and determine managerial or safety actions needed to prevent similar occurrences. DOE safety requirements include the reporting of personnel injury, property and motor vehicle losses on a quarterly basis, and radiation doses on an annual basis. The radiation dose data for CY 1978 are presented and reviewed in this report. All other data in this report are for FY 1978

  20. 75 FR 21157 - Milk in the Northeast and Other Marketing Areas; Order Amending the Orders

    Science.gov (United States)

    2010-04-23

    ... INFORMATION: This final rule amends the producer-handler provisions of all Federal milk marketing orders to... producer-handlers under the Federal milk marketing order system to the same terms as other fully regulated... considered producer-handlers under the Federal order system, the impact is offset by the benefit to other...

  1. 20 CFR 355.24 - Protective order.

    Science.gov (United States)

    2010-04-01

    ... REGULATIONS UNDER THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 355.24 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by... more of the following: (1) That the discovery not be had; (2) That the discovery may be had only on...

  2. 77 FR 12205 - Mevinphos; Order Revoking Tolerances

    Science.gov (United States)

    2012-02-29

    ... readers regarding entities likely to be affected by this action. Other types of entities not listed in... commodities listed in the regulatory text of this document that are treated with the pesticide subject to this... Executive Orders 13132, and 13175 This order directly regulates growers, food processors, food handlers and...

  3. Accident analysis and DOE criteria

    International Nuclear Information System (INIS)

    Graf, J.M.; Elder, J.C.

    1982-01-01

    In analyzing the radiological consequences of major accidents at DOE facilities one finds that many facilities fall so far below the limits of DOE Order 6430 that compliance is easily demonstrated by simple analysis. For those cases where the amount of radioactive material and the dispersive energy available are enough for accident consequences to approach the limits, the models and assumptions used become critical. In some cases the models themselves are the difference between meeting the criteria or not meeting them. Further, in one case, we found that not only did the selection of models determine compliance but the selection of applicable criteria from different chapters of Order 6430 also made the difference. DOE has recognized the problem of different criteria in different chapters applying to one facility, and has proceeded to make changes for the sake of consistency. We have proposed to outline the specific steps needed in an accident analysis and suggest appropriate models, parameters, and assumptions. As a result we feed DOE siting and design criteria will be more fairly and consistently applied

  4. Prevention of triplets and higher order multiples: trends in reproductive medicine.

    Science.gov (United States)

    Armour, Kim L; Callister, Lynn Clark

    2005-01-01

    In the United States and throughout the world, today's healthcare providers are challenged by the risks of multiple gestation pregnancy. Assisted reproductive technologies (ARTs) often used to treat infertility raise ethical issues including informed consent, veracity, and nonmalificence. In the United States, there is the need to improve maternal and fetal/neonatal mortality and morbidity by proposing legislation regulating ART and supporting single embryo transfers with no more than 2 such transfers. Beginning with the diagnosis of infertility, providers have a responsibility to educate, inform, and treat infertile couples. From the moment pregnancy with multiples is confirmed, these families are faced with incredible stressors including decision making on multifetal or selective reduction. Full disclosure of risks involved throughout the course of care should be discussed and documented in the record and plan of care. Currently in the United States, legislation does not regulate ART, including ovulation induction/enhancement and in vitro fertilization. Although the United States does have self-regulation via limited reporting through their professional organization and the Centers for Disease Control and Prevention, an unlimited number of embryos may be transferred. Unfortunately, many healthcare providers have not recognized the responsibility and burden placed on families and society as a whole. Lack of regulation means women may become pregnant with high order multiples, which raises serious moral and ethical issues.

  5. Quality assurance grading guidelines for research and development at DOE facilities

    Energy Technology Data Exchange (ETDEWEB)

    Powell, T.B.; Morris, R.N.

    1993-01-01

    The quality assurance (QA) requirements for the US Department of Energy (DOE) are established in DOE Order 5700.6C. This order is applicable for all DOE departmental elements, management, and maintenance and operating contractors and requires that documented Quality Assurance Programs (QAPs) are prepared at all levels; it has one attachment. The DOE Office of Energy Research (DOE-ER) has issued a standard to ensure implementation of the full intent of this order in the ER community.

  6. First-order inflation

    International Nuclear Information System (INIS)

    Kolb, E.W.

    1991-01-01

    In the original proposal, inflation occurred in the process of a strongly first-order phase transition. This model was soon demonstrated to be fatally flawed. Subsequent models for inflation involved phase transitions that were second-order, or perhaps weakly first-order; some even involved no phase transition at all. Recently the possibility of inflation during a strongly first-order phase transition has been reviewed. In this talk I will discuss some models for first-order inflation, and emphasize unique signatures that result if inflation is realized in a first-order transition. Before discussing first-order inflation, I will briefly review some of the history of inflation to demonstrate how first-order inflation differs from other models. (orig.)

  7. First-order inflation

    International Nuclear Information System (INIS)

    Kolb, E.W.; Chicago Univ., IL

    1990-09-01

    In the original proposal, inflation occurred in the process of a strongly first-order phase transition. This model was soon demonstrated to be fatally flawed. Subsequent models for inflation involved phase transitions that were second-order, or perhaps weakly first-order; some even involved no phase transition at all. Recently the possibility of inflation during a strongly first-order phase transition has been revived. In this talk I will discuss some models for first-order inflation, and emphasize unique signatures that result in inflation is realized in a first-order transition. Before discussing first-order inflation, I will briefly review some of the history of inflation to demonstrate how first-order inflation differs from other models. 58 refs., 3 figs

  8. 10 CFR 820.41 - Compliance order.

    Science.gov (United States)

    2010-01-01

    .... The Secretary may issue to any person involved in a DOE nuclear activity a Compliance Order that: (a) Identifies a situation that violates, potentially violates, or otherwise is inconsistent with the Act, a...) States the reasons for the remedy or other action. ...

  9. The practical outfall of DOE compliance agreements

    International Nuclear Information System (INIS)

    Smith, Leanne; Henrie, Gregory O.

    1992-01-01

    Perhaps the significant regulatory issue facing the Department of Energy (DOE or the Department) is the compliant treatment, storage, and disposal of mixed (radioactive and hazardous) waste. Since DOE'S By-Product Rulemaking in 1987, when the Department acknowledged that the Resource Conservation and Recovery Act (RCRA) applied to the hazardous component of mixed waste, DOE has repeatedly communicated to the Environmental Protection Agency (EPA) and host States that, for mixed waste, DOE is not always able to strictly comply with RCRA standards and that bringing treatment on-line in an expeditious manner is proving very difficult. One of the most effective methods used between DOE and its regulators to address mixed waste management issues is the negotiation of compliance agreements. These agreements establish formal mile stones for bringing DOE sites into compliance. The milestones are not completed without overcoming technical roadblocks and a struggle for funding. However, agreements can establish technically attainable compliance methods that take into account the special problems radiation introduces into RCRA waste management. Compliance agreements help promote a cooperative relationship within the Department and between DOE and its regulators in that all parties have reached agreement and have a stake in attaining the same goal. Where agreements exist, mixed waste compliance efforts can proceed in a situation where all parties have a full understanding of each other's needs and expectations. (author)

  10. 77 FR 36119 - Pistachios Grown in California, Arizona, and New Mexico; Order Amending Marketing Order No. 983

    Science.gov (United States)

    2012-06-18

    ...; FV11-983-1 FR] Pistachios Grown in California, Arizona, and New Mexico; Order Amending Marketing Order... amends Marketing Agreement and Order No. 983 (order), which regulates the handling of pistachios grown in... Committee for Pistachios (Committee), which is responsible for local administration of the order. The...

  11. Ordered bulk degradation via autophagy

    DEFF Research Database (Denmark)

    Dengjel, Jörn; Kristensen, Anders Riis; Andersen, Jens S

    2008-01-01

    During amino acid starvation, cells undergo macroautophagy which is regarded as an unspecific bulk degradation process. Lately, more and more organelle-specific autophagy subtypes such as reticulophagy, mitophagy and ribophagy have been described and it could be shown, depending on the experimental...... at proteasomal and lysosomal degradation ample cross-talk between the two degradation pathways became evident. Degradation via autophagy appeared to be ordered and regulated at the protein complex/organelle level. This raises several important questions such as: can macroautophagy itself be specific and what...

  12. Status of DOE defense waste management policy

    International Nuclear Information System (INIS)

    Oertel, K.G.; Scott, R.S.

    1983-01-01

    This paper very briefly traces the statutory basis for DOE management of atomic energy defense activity wastes, touches on the authority of the Federal agencies involved in the regulation of defense nuclear waste management, and addresses the applicable regulations and their status. This background sets the stage for a fairly detailed discussion of management and disposal strategies of the Defense Waste and Byproducts Management Program

  13. 7 CFR 987.48 - Container regulation.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Container regulation. 987.48 Section 987.48... IN RIVERSIDE COUNTY, CALIFORNIA Order Regulating Handling Container Regulation § 987.48 Container regulation. Whenever the Committee deems it advisable to establish a container regulation for any variety of...

  14. Using GIS to develop socio-economic profiles of areas adjacent to DOE facilities

    International Nuclear Information System (INIS)

    Stewart, J.C.; Saraswatula, S.

    1994-01-01

    The objective of the research addressed in this paper is to identify and analyze the offsite effects of DOE activities at the Savannah River Site. The paper presents the socio-economic conditions of the areas surrounding the site in order to evaluate the possible effects of DOE activities. The study employed a geographic information system (GIS) in order to evaluate spatial relationships between otherwise unrelated factors. Socio-economic data used in the study are publicly available and were obtained mainly from the Bureau of the Census. The Department of Energy (DOE), currently dealing with the environmental management of a large number of sites throughout the United States, must consider the effects of its activities on surrounding populations and ensure compliance with the various federal regulations, such as the executive order on environmental justice. Environmental justice is the process of studying and achieving equal distribution of the effects of environmental pollution on populations across social and economic lines. An executive order signed by the President has directed federal agencies, including the Department of Energy, to make achieving environmental justice a part of the agency's mission by identifying and addressing disproportionately high and adverse human health or environmental effects of its programs, policies, and activities on minority and low-income populations

  15. Quantitative framework for ordered degradation of APC/C substrates.

    Science.gov (United States)

    Lu, Dan; Girard, Juliet R; Li, Weihan; Mizrak, Arda; Morgan, David O

    2015-11-16

    During cell-cycle progression, substrates of a single master regulatory enzyme can be modified in a specific order. Here, we used experimental and computational approaches to dissect the quantitative mechanisms underlying the ordered degradation of the substrates of the ubiquitin ligase APC/C(Cdc20), a key regulator of chromosome segregation in mitosis. We show experimentally that the rate of catalysis varies with different substrates of APC/C(Cdc20). Using a computational model based on multi-step ubiquitination, we then show how changes in the interaction between a single substrate and APC/C(Cdc20) can alter the timing of degradation onset relative to APC/C(Cdc20) activation, while ensuring a fast degradation rate. Degradation timing and dynamics depend on substrate affinity for the enzyme as well as the catalytic rate at which the substrate is modified. When two substrates share the same pool of APC/C(Cdc20), their relative enzyme affinities and rates of catalysis influence the partitioning of APC/C(Cdc20) among substrates, resulting in substrate competition. Depending on how APC/C(Cdc20) is partitioned among its substrates, competition can have minor or major effects on the degradation of certain substrates. We show experimentally that increased expression of the early APC/C(Cdc20) substrate Clb5 does not delay the degradation of the later substrate securin, arguing against a role for competition with Clb5 in establishing securin degradation timing. The degradation timing of APC/C(Cdc20) substrates depends on the multi-step nature of ubiquitination, differences in substrate-APC/C(Cdc20) interactions, and competition among substrates. Our studies provide a conceptual framework for understanding how ordered modification can be established among substrates of the same regulatory enzyme, and facilitate our understanding of how precise temporal control is achieved by a small number of master regulators to ensure a successful cell division cycle.

  16. Fractional-order devices

    CERN Document Server

    Biswas, Karabi; Caponetto, Riccardo; Mendes Lopes, António; Tenreiro Machado, José António

    2017-01-01

    This book focuses on two specific areas related to fractional order systems – the realization of physical devices characterized by non-integer order impedance, usually called fractional-order elements (FOEs); and the characterization of vegetable tissues via electrical impedance spectroscopy (EIS) – and provides readers with new tools for designing new types of integrated circuits. The majority of the book addresses FOEs. The interest in these topics is related to the need to produce “analogue” electronic devices characterized by non-integer order impedance, and to the characterization of natural phenomena, which are systems with memory or aftereffects and for which the fractional-order calculus tool is the ideal choice for analysis. FOEs represent the building blocks for designing and realizing analogue integrated electronic circuits, which the authors believe hold the potential for a wealth of mass-market applications. The freedom to choose either an integer- or non-integer-order analogue integrator...

  17. Order Management - Today's focus

    DEFF Research Database (Denmark)

    Barfod, Ari

    1996-01-01

    Small and mid-range companies throughout the world have moved towards customer-specific production during the last few years, but often, the order flow has not changed to meet new demands. Customer orders pass through a laarge number of departments, such as sales, construction, pre...... to the final product.In the paper, a new method for improving order flow is presented, including an extended use of activity chain models....

  18. Color ordering in QCD

    OpenAIRE

    Schuster, Theodor

    2013-01-01

    We derive color decompositions of arbitrary tree and one-loop QCD amplitudes into color ordered objects called primitive amplitudes. Furthermore, we derive general fermion flip and reversion identities spanning the null space among the primitive amplitudes and use them to prove that all color ordered tree amplitudes of massless QCD can be written as linear combinations of color ordered tree amplitudes of $\\mathcal{N}=4$ super Yang-Mills theory.

  19. Does calcium influx regulate melatonin production through the circadian pacemaker in chick pineal cells? Effects of nitrendipine, Bay K 8644, Co2+, Mn2+, and low external Ca2+.

    Science.gov (United States)

    Zatz, M; Mullen, D A

    1988-11-01

    We have recently described a system, using dispersed chick pineal cells in static culture, which displays a persistent, photosensitive, circadian rhythm of melatonin production and release. Here, we describe the effects of nitrendipine (NTR) (a dihydropyridine 'antagonist' of L-type calcium channels), Bay K 8644 (BK) (a dihydropyridine calcium channel 'agonist'), cobalt and manganese ions (both inorganic calcium channel blockers), and low external calcium concentrations, on the melatonin rhythm. NTR inhibited and BK stimulated melatonin output; they were potent and effective. Co2+, Mn2+, and low external Ca2+ markedly inhibited melatonin output. These results support a role for calcium influx through voltage-dependent calcium channels (L-type) in the regulation of melatonin production. Four or 8 h pulses of white light or darkness, in otherwise constant red light, cause, in addition to acute effects, phase-dependent phase shifts of the melatonin rhythm in subsequent cycles. Such phase shifts indicate an effect on (proximal to) the pacemaker generating the rhythm. Four or 8 h pulses of NTR, BK, Co2+, or low Ca2+, however, did not appreciably alter the phase of subsequent melatonin cycles. Neither did BK interfere with phase shifts induced by light pulses. Mn2+ pulses did induce phase-dependent phase shifts, but, unlike those evoked by light or dark pulses, these were all delays. Such effects of Mn2+ in other systems have been attributed to, and are characteristic of, 'metabolic inhibitors'. On balance, the results fail to support a prominent role for calcium influx in regulating the pacemaker underlying the circadian rhythm in chick pineal cells. Rather, calcium influx appears to regulate melatonin production primarily by acting on the melatonin-synthesizing apparatus, distal to the pacemaker.

  20. Moving from self-regulation to external regulation of Department of Energy facilities

    International Nuclear Information System (INIS)

    Wishau, R.J.; Dawson, J.; Lee, D.W.

    1999-01-01

    This paper discusses the initiative to transfer the regulation of Department of Energy (DOE) nuclear facilities to the US Nuclear Regulatory Commission (NRC). The paper gives an overview of some of the major technical, policy and legal issues that accompany this initiative. The paper focuses on specific issues and how they may be affected by external regulation of occupational radiation protection at DOE facilities. Differences between the NRC and the DOE approach to regulating nuclear safety are compared and contrasted. Some projected impacts from this transition are examined. Finally, recommendations are provided that may enhance the transition, increasing the likelihood of successful external NRC regulation

  1. Program management strategies for following EPA guidance for remedial design/remedial action at DOE sites

    International Nuclear Information System (INIS)

    Hopper, J.P.; Chew, J.R.; Kowalski, T.E.

    1991-01-01

    At the US Department of Energy (DOE) facilities, environmental restoration is being conducted in accordance with Federal Facilities Compliance Agreements (or Interagency Agreements). These agreements establish a cooperative working relationship and often define roles, responsibilities and authorities for conduct and oversight of the Remedial Action Programs. The US Environmental Protection Agency (EPA) has guidelines on how to initiate and perform remedial actions for sites they are remediating under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) as amended by the Superfund Amendments and Re-Authorization Act (SARA). This paper addresses some of the difference and commonalities between the DOE project management procedures and EPA guidance documents. This report covers only the RD/RA phase of environmental restoration. On the surface, there are many apparent differences between the DOE and EPA project management processes. Upon closer review, however, many of the differences are the result of applying different terminology to the same phase of a project. By looking for the similarities in the two processes rather than hunting for differences, many communication problems are avoided. Understanding both processes also aids in figuring out when, how and to what extent EPA should participate in the RD/RA phase for DOE lead cleanup activities. The DOE Remedial Design and Remedial Action process is discussed in a stepwise manner and compared to the EPA process. Each element of the process is defined. Activities common to both the EPA and DOE are correlated. The annual DOE budget cycle for remediation projects and the four-year cycle for appropriation of remediation funds are discussed, and the constraints of this process examined. DOE orders as well as other requirements for RD/RA activities are summarized and correlated to EPA regulations where this is possible

  2. DOE site performance assessment activities

    International Nuclear Information System (INIS)

    1990-07-01

    Information on performance assessment capabilities and activities was collected from eight DOE sites. All eight sites either currently dispose of low-level radioactive waste (LLW) or plan to dispose of LLW in the near future. A survey questionnaire was developed and sent to key individuals involved in DOE Order 5820.2A performance assessment activities at each site. The sites surveyed included: Hanford Site (Hanford), Idaho National Engineering Laboratory (INEL), Los Alamos National Laboratory (LANL), Nevada Test Site (NTS), Oak Ridge National Laboratory (ORNL), Paducah Gaseous Diffusion Plant (Paducah), Portsmouth Gaseous Diffusion Plant (Portsmouth), and Savannah River Site (SRS). The questionnaire addressed all aspects of the performance assessment process; from waste source term to dose conversion factors. This report presents the information developed from the site questionnaire and provides a comparison of site-specific performance assessment approaches, data needs, and ongoing and planned activities. All sites are engaged in completing the radioactive waste disposal facility performance assessment required by DOE Order 5820.2A. Each site has achieved various degrees of progress and have identified a set of critical needs. Within several areas, however, the sites identified common needs and questions

  3. Order in Chaos

    DEFF Research Database (Denmark)

    Hansen, Bertel Teilfeldt; Olsen, Asmus Leth

    2014-01-01

    Ballot order effects are well documented in established democracies, but less so in fragile post-conflict settings. We test for the presence of ballot order effects in the 2010 parliamentary election in Afghanistan. Turning out for the 2010 election was a potentially life-threatening endeavor for...

  4. Put order picking system

    Directory of Open Access Journals (Sweden)

    Đurđević Dragan D.

    2014-01-01

    Full Text Available Nowadays the warehouse is very important logistic component of the supply chain, where order-picking systems have important role. Due to the significant impact on logistics performance permanent goals are to increase efficiency and reduce the cost of these systems. To achieve these goals, there are different researches, and their success is determined by the achieved performances. Performances order picking process are dependent on the applied technology concepts of order-picking system, as well as the ways in which it is organized and managed. In addition to the standard conceptions (the man to good and good to the man is one of the newer, so-called. 'put' system - the inverse order-picking. The aim of this paper is to describe this concept, point out its core strengths and weaknesses and provide a basis that may be of importance in the development of warehouse technological solutions and application of this order-picking systems concept.

  5. Narcissism and birth order.

    Science.gov (United States)

    Eyring, W E; Sobelman, S

    1996-04-01

    The purpose of this investigation was to clarify the relationship between birth-order position and the development of narcissism, while refining research and theory. The relationship between birth-order status and narcissism was examined with a sample of 79 undergraduate students (55 women and 24 men). These subjects were placed in one of the four following birth-order categories of firstborn, second-born, last-born, and only children. These categories were chosen given their significance in Adlerian theory. Each subject completed the Narcissistic Personality Inventory and a demographic inventory. Based on psychodynamic theory, it was hypothesized that firstborn children were expected to score highest, but statistical significance was not found for an association between narcissism and birth order. Further research is urged to investigate personality theory as it relates to parenting style and birth order.

  6. Symbols of a cosmic order

    Science.gov (United States)

    Madjid, F. Hadi; Myers, John M.

    2016-10-01

    The world runs on networks over which signals communicate sequences of symbols, e.g. numerals. Examining both engineered and natural communications networks reveals an unsuspected order that depends on contact with an unpredictable entity. This order has three roots. The first is a proof within quantum theory that no evidence can ever determine its explanation, so that an agent choosing an explanation must do so unpredictably. The second root is the showing that clocks that step computers do not "tell time" but serve as self-adjusting symbol-handling agents that regulate "logically synchronized" motion in response to unpredictable disturbances. Such a clock-agent has a certain independence as well as the capacity to communicate via unpredictable symbols with other clock-agents and to adjust its own tick rate in response to that communication. The third root is the noticing of unpredictable symbol exchange in natural systems, including the transmission of symbols found in molecular biology. We introduce a symbol-handling agent as a role played in some cases by a person, for example a physicist who chooses an explanation of given experimental outcomes, and in other cases by some other biological entity, and in still other cases by an inanimate device, such as a computer-based detector used in physical measurements. While we forbear to try to explain the propensity of agents at all levels from cells to civilizations to form and operate networks of logically synchronized symbol-handling agents, we point to this propensity as an overlooked cosmic order, an order structured by the unpredictability ensuing from the proof. Appreciating the cosmic order leads to a conception of agency that replaces volition by unpredictability and reconceives the notion of objectivity in a way that makes a place for agency in the world as described by physics. Some specific implications for physics are outlined.

  7. Robust Stabilization of Fractional-Order Systems with Interval Uncertainties via Fractional-Order Controllers

    Directory of Open Access Journals (Sweden)

    Mohammadtaghi Hamidi Beheshti

    2010-01-01

    Full Text Available We propose a fractional-order controller to stabilize unstable fractional-order open-loop systems with interval uncertainty whereas one does not need to change the poles of the closed-loop system in the proposed method. For this, we will use the robust stability theory of Fractional-Order Linear Time Invariant (FO-LTI systems. To determine the control parameters, one needs only a little knowledge about the plant and therefore, the proposed controller is a suitable choice in the control of interval nonlinear systems and especially in fractional-order chaotic systems. Finally numerical simulations are presented to show the effectiveness of the proposed controller.

  8. Regulating nuclear fuel waste

    International Nuclear Information System (INIS)

    1995-01-01

    When Parliament passed the Atomic Energy Control Act in 1946, it erected the framework for nuclear safety in Canada. Under the Act, the government created the Atomic Energy Control Board and gave it the authority to make and enforce regulations governing every aspect of nuclear power production and use in this country. The Act gives the Control Board the flexibility to amend its regulations to adapt to changes in technology, health and safety standards, co-operative agreements with provincial agencies and policy regarding trade in nuclear materials. This flexibility has allowed the Control Board to successfully regulate the nuclear industry for more than 40 years. Its mission statement 'to ensure that the use of nuclear energy in Canada does not pose undue risk to health, safety, security and the environment' concisely states the Control Board's primary objective. The Atomic Energy Control Board regulates all aspects of nuclear energy in Canada to ensure there is no undue risk to health, safety, security or the environment. It does this through a multi-stage licensing process

  9. DOE handbook electrical safety

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-01

    Electrical Safety Handbook presents the Department of Energy (DOE) safety standards for DOE field offices or facilities involved in the use of electrical energy. It has been prepared to provide a uniform set of electrical safety guidance and information for DOE installations to effect a reduction or elimination of risks associated with the use of electrical energy. The objectives of this handbook are to enhance electrical safety awareness and mitigate electrical hazards to employees, the public, and the environment.

  10. Mathematics of aperiodic order

    CERN Document Server

    Lenz, Daniel; Savinien, Jean

    2015-01-01

    What is order that is not based on simple repetition, that is, periodicity? How must atoms be arranged in a material so that it diffracts like a quasicrystal? How can we describe aperiodically ordered systems mathematically? Originally triggered by the – later Nobel prize-winning – discovery of quasicrystals, the investigation of aperiodic order has since become a well-established and rapidly evolving field of mathematical research with close ties to a surprising variety of branches of mathematics and physics. This book offers an overview of the state of the art in the field of aperiodic order, presented in carefully selected authoritative surveys. It is intended for non-experts with a general background in mathematics, theoretical physics or computer science, and offers a highly accessible source of first-hand information for all those interested in this rich and exciting field. Topics covered include the mathematical theory of diffraction, the dynamical systems of tilings or Delone sets, their cohomolog...

  11. Order-Disorder Theory

    International Nuclear Information System (INIS)

    Kasteleyn, P.W.

    1971-01-01

    Apology. 1. Order-disorder transitions; 2. The Ising model; 3. The classical theories; 4. The exact analysis of the Ising model; 5. Series expansions; 6. Relations between critical indices; 7. Other models; 8. Concluding remarks. (author)

  12. Ordered groups and topology

    CERN Document Server

    Clay, Adam

    2016-01-01

    This book deals with the connections between topology and ordered groups. It begins with a self-contained introduction to orderable groups and from there explores the interactions between orderability and objects in low-dimensional topology, such as knot theory, braid groups, and 3-manifolds, as well as groups of homeomorphisms and other topological structures. The book also addresses recent applications of orderability in the studies of codimension-one foliations and Heegaard-Floer homology. The use of topological methods in proving algebraic results is another feature of the book. The book was written to serve both as a textbook for graduate students, containing many exercises, and as a reference for researchers in topology, algebra, and dynamical systems. A basic background in group theory and topology is the only prerequisite for the reader.

  13. Mobile food ordering application

    OpenAIRE

    Yang, Fan

    2014-01-01

    The purpose of this thesis was to build a food ordering client server application for Tom Yum Thai Oy, which is a Thai restaurant in Vaasa. For the customer, this application provides a view of current food information (category, name, image,price, description etc.) on the website and Android application. The customer can order food from these two platforms. For the administrator in restaurant, this application offers a series of operations to add, update, delete and query the information of ...

  14. Operator ordering and causality

    OpenAIRE

    Plimak, L. I.; Stenholm, S. T.

    2011-01-01

    It is shown that causality violations [M. de Haan, Physica 132A, 375, 397 (1985)], emerging when the conventional definition of the time-normal operator ordering [P.L.Kelley and W.H.Kleiner, Phys.Rev. 136, A316 (1964)] is taken outside the rotating wave approximation, disappear when the amended definition [L.P. and S.S., Annals of Physics, 323, 1989 (2008)] of this ordering is used.

  15. Ordered Consumer Search

    OpenAIRE

    Armstrong, Mark

    2016-01-01

    The paper discusses situations in which consumers search through their options in a deliberate order, in contrast to more familiar models with random search. Topics include: network effects (consumers may be better off following the same search order as other consumers); the use of price and non-price advertising to direct search; the impact of consumers starting a new search with their previous supplier; the incentive sellers have to merge or co-locate with other sellers; and the incentive a...

  16. 16 CFR 460.23 - Other laws, rules, and orders.

    Science.gov (United States)

    2010-01-01

    ... Desist Order applies to you but differs from the rules given here, you can petition to amend to order. (b) State and local laws and regulations that are inconsistent with, or frustrate the purposes of, the provisions of this regulation are preempted. However, a State or local government may petition the Commission...

  17. 29 CFR 102.116 - Signature of orders.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Signature of orders. 102.116 Section 102.116 Labor Regulations Relating to Labor NATIONAL LABOR RELATIONS BOARD RULES AND REGULATIONS, SERIES 8 Certification and Signature of Documents § 102.116 Signature of orders. The executive secretary or the associate executive...

  18. 17 CFR 242.604 - Display of customer limit orders.

    Science.gov (United States)

    2010-04-01

    ... such security; and (ii) The full size of each customer limit order held by the OTC market maker that... in relation to the size associated with the OTC market maker's bid or offer. (b) Exceptions. The... Regulation Nms-Regulation of the National Market System § 242.604 Display of customer limit orders. (a...

  19. 7 CFR 1001.85 - Assessment for order administration.

    Science.gov (United States)

    2010-01-01

    ... 1001.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE NORTHEAST MARKETING AREA Order Regulating Handling Administrative Assessment and Marketing Service Deduction § 1001.85...

  20. 7 CFR 1033.85 - Assessment for order administration.

    Science.gov (United States)

    2010-01-01

    ... 1033.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE MIDEAST MARKETING AREA Order Regulating Handling Administrative Assessment and Marketing Service Deduction § 1033.85...

  1. 7 CFR 1032.85 - Assessment for order administration.

    Science.gov (United States)

    2010-01-01

    ... 1032.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE CENTRAL MARKETING AREA Order Regulating Handling Administrative Assessment and Marketing Service Deduction § 1032.85...

  2. 7 CFR 1126.85 - Assessment for order administration.

    Science.gov (United States)

    2010-01-01

    ... 1126.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHWEST MARKETING AREA Order Regulating Handling Administrative Assessment and Marketing Service Deduction § 1126.85...

  3. 7 CFR 1124.85 - Assessment for order administration.

    Science.gov (United States)

    2010-01-01

    ... 1124.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE PACIFIC NORTHWEST MARKETING AREA Order Regulating Handling Administrative Assessment and Marketing Service Deduction § 1124.85...

  4. 7 CFR 1006.85 - Assessment for order administration.

    Science.gov (United States)

    2010-01-01

    ... 1006.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE FLORIDA MARKETING AREA Order Regulating Handling Administrative Assessment and Marketing Service Deduction § 1006.85...

  5. 7 CFR 1007.85 - Assessment for order administration.

    Science.gov (United States)

    2010-01-01

    ... 1007.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHEAST MARKETING AREA Order Regulating Handling Administrative Assessment and Marketing Service Deduction § 1007.85...

  6. 7 CFR 1131.85 - Assessment for order administration.

    Science.gov (United States)

    2010-01-01

    ... 1131.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE ARIZONA MARKETING AREA Order Regulating Handling Administrative Assessment and Marketing Service Deduction § 1131.85...

  7. 7 CFR 1005.85 - Assessment for order administration.

    Science.gov (United States)

    2010-01-01

    ... 1005.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE APPALACHIAN MARKETING AREA Order Regulating Handling Administrative Assessment and Marketing Service Deduction § 1005.85...

  8. Interpersonal emotion regulation.

    Science.gov (United States)

    Zaki, Jamil; Williams, W Craig

    2013-10-01

    Contemporary emotion regulation research emphasizes intrapersonal processes such as cognitive reappraisal and expressive suppression, but people experiencing affect commonly choose not to go it alone. Instead, individuals often turn to others for help in shaping their affective lives. How and under what circumstances does such interpersonal regulation modulate emotional experience? Although scientists have examined allied phenomena such as social sharing, empathy, social support, and prosocial behavior for decades, there have been surprisingly few attempts to integrate these data into a single conceptual framework of interpersonal regulation. Here we propose such a framework. We first map a "space" differentiating classes of interpersonal regulation according to whether an individual uses an interpersonal regulatory episode to alter their own or another person's emotion. We then identify 2 types of processes--response-dependent and response-independent--that could support interpersonal regulation. This framework classifies an array of processes through which interpersonal contact fulfills regulatory goals. More broadly, it organizes diffuse, heretofore independent data on "pieces" of interpersonal regulation, and identifies growth points for this young and exciting research domain.

  9. 2 CFR 801.10 - What does this part do?

    Science.gov (United States)

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false What does this part do? 801.10 Section 801.10 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF VETERANS AFFAIRS NONPROCUREMENT DEBARMENT AND SUSPENSION § 801.10 What does this part do? This part adopts the...

  10. Clinical research involving minors in international and serbian regulations.

    Science.gov (United States)

    Planojević, Nina; Zivojinović, Dragica

    2013-07-01

    Participation in clinical trials can be useful for the health of a person, in who it is conducted, but it does not have to be - it can even be harmful. Therefore, primary motive to accept such risk is humanity and human wish to contribute to the progress of medicine; this is expressed by personal consent. The consent, however, can be an expression of personal humanity, and for this, it is not logical that someone can give consent on behalf of someone else, as it is done by a legally authorized representative on behalf of a minor. Therefore, authors raise 3 questions: What are the reasons to consider representative's consent acceptable? How should a model of regulations look like in order to provide the most complete possible protection to a minor? Is actual regulation of minors' position within international and Serbian law, analyzed here by authors for their specific solutions, acceptable? Representative's consent is acceptable only for therapeutic research, because these can bring benefits to everyone's health, including a minor in which those are conducted - this is an acceptable (secondary) motive of participation in the research. Expression of humanity on other's behalf, typical for non-therapeutic research, is not acceptable; this makes ban of minors' participation in non-therapeutic research more appropriate regulation model. International regulations are not in accordance to results presented in the paper for allowing participation of minors both in therapeutic and non-therapeutic research. Serbian regulation is closer to the most acceptable regulation model.

  11. ORDERED WEIGHTED DISTANCE MEASURE

    Institute of Scientific and Technical Information of China (English)

    Zeshui XU; Jian CHEN

    2008-01-01

    The aim of this paper is to develop an ordered weighted distance (OWD) measure, which is thegeneralization of some widely used distance measures, including the normalized Hamming distance, the normalized Euclidean distance, the normalized geometric distance, the max distance, the median distance and the min distance, etc. Moreover, the ordered weighted averaging operator, the generalized ordered weighted aggregation operator, the ordered weighted geometric operator, the averaging operator, the geometric mean operator, the ordered weighted square root operator, the square root operator, the max operator, the median operator and the min operator axe also the special cases of the OWD measure. Some methods depending on the input arguments are given to determine the weights associated with the OWD measure. The prominent characteristic of the OWD measure is that it can relieve (or intensify) the influence of unduly large or unduly small deviations on the aggregation results by assigning them low (or high) weights. This desirable characteristic makes the OWD measure very suitable to be used in many actual fields, including group decision making, medical diagnosis, data mining, and pattern recognition, etc. Finally, based on the OWD measure, we develop a group decision making approach, and illustrate it with a numerical example.

  12. Arguments from Developmental Order.

    Science.gov (United States)

    Stöckle-Schobel, Richard

    2016-01-01

    In this article, I investigate a special type of argument regarding the role of development in theorizing about psychological processes and cognitive capacities. Among the issues that developmental psychologists study, discovering the ontogenetic trajectory of mechanisms or capacities underpinning our cognitive functions ranks highly. The order in which functions are developed or capacities are acquired is a matter of debate between competing psychological theories, and also philosophical conceptions of the mind - getting the role and the significance of the different steps in this order right could be seen as an important virtue of such theories. Thus, a special kind of strategy in arguments between competing philosophical or psychological theories is using developmental order in arguing for or against a given psychological claim. In this article, I will introduce an analysis of arguments from developmental order, which come in two general types: arguments emphasizing the importance of the early cognitive processes and arguments emphasizing the late cognitive processes. I will discuss their role in one of the central tools for evaluating scientific theories, namely in making inferences to the best explanation. I will argue that appeal to developmental order is, by itself, an insufficient criterion for theory choice and has to be part of an argument based on other core explanatory or empirical virtues. I will end by proposing a more concerted study of philosophical issues concerning (cognitive) development, and I will present some topics that also pertain to a full-fledged 'philosophy of development.'

  13. Birth order and psychopathology.

    Science.gov (United States)

    Risal, Ajay; Tharoor, Hema

    2012-07-01

    Ordinal position the child holds within the sibling ranking of a family is related to intellectual functioning, personality, behavior, and development of psychopathology. To study the association between birth order and development of psychopathology in patients attending psychiatry services in a teaching hospital. Hospital-based cross-sectional study. Retrospective file review of three groups of patients was carried out. Patient-related variables like age of onset, birth order, family type, and family history of mental illness were compared with psychiatry diagnosis (ICD-10) generated. SPSS 13; descriptive statistics and one-way analysis of variance (ANOVA) were used. Mean age of onset of mental illness among the adult general psychiatry patients (group I, n = 527) was found to be 33.01 ± 15.073, while it was 11.68 ± 4.764 among the child cases (group II, n = 47) and 26.74 ± 7.529 among substance abuse cases (group III, n = 110). Among group I patients, commonest diagnosis was depression followed by anxiety and somatoform disorders irrespective of birth order. Dissociative disorders were most prevalent in the first born child (36.7%) among group II patients. Among group III patients, alcohol dependence was maximum diagnosis in all birth orders. Depression and alcohol dependence was the commonest diagnosis in adult group irrespective of birth order.

  14. Birth Order and Psychopathology

    Directory of Open Access Journals (Sweden)

    Ajay Risal

    2012-01-01

    Full Text Available Context: Ordinal position the child holds within the sibling ranking of a family is related to intellectual functioning, personality, behavior, and development of psychopathology. Aim: To study the association between birth order and development of psychopathology in patients attending psychiatry services in a teaching hospital. Settings and Design: Hospital-based cross-sectional study. Materials and Methods: Retrospective file review of three groups of patients was carried out. Patient-related variables like age of onset, birth order, family type, and family history of mental illness were compared with psychiatry diagnosis (ICD-10 generated. Statistical Analysis: SPSS 13; descriptive statistics and one-way analysis of variance (ANOVA were used. Results: Mean age of onset of mental illness among the adult general psychiatry patients (group I, n = 527 was found to be 33.01 ± 15.073, while it was 11.68 ± 4.764 among the child cases (group II, n = 47 and 26.74 ± 7.529 among substance abuse cases (group III, n = 110. Among group I patients, commonest diagnosis was depression followed by anxiety and somatoform disorders irrespective of birth order. Dissociative disorders were most prevalent in the first born child (36.7% among group II patients. Among group III patients, alcohol dependence was maximum diagnosis in all birth orders. Conclusions: Depression and alcohol dependence was the commonest diagnosis in adult group irrespective of birth order.

  15. The birth order puzzle.

    Science.gov (United States)

    Zajonc, R B; Markus, H; Markus, G B

    1979-08-01

    Studies relating intellectual performance to birth order report conflicting results, some finding intellectual scores to increase, others to decrease with birth order. In contrast, the relationship between intellectual performance and family size is stable and consistently replicable. Why do these two highly related variables generate such divergent results? This birth order puzzle is resolved by means of the confluence model that quantifies the influences upon intellectual growth arising within the family context. At the time of a new birth, two opposing influences act upon intellectual growth of the elder sibling: (a) his or her intellectual environment is "diluted" and (b) he or she loses the "last-born's handicap" and begins serving as an intellectual resource to the younger sibling. Since these opposite effects are not equal in magnitude, the differences in intellectual performance among birth ranks are shown to be age dependent. While elder children may surpass their younger siblings in intellectual performance at some ages, they may be overtaken by them at others. Thus when age is taken into consideration, the birth order literature loses its chaotic character and an orderly pattern of results emerges.

  16. Arguments from Developmental Order

    Directory of Open Access Journals (Sweden)

    Richard eStöckle-Schobel

    2016-05-01

    Full Text Available In this article, I investigate a special type of argument regarding the role of development in theorising about psychological processes and cognitive capacities. Among the issues that developmental psychologists study, discovering the ontogenetic trajectory of mechanisms or capacities underpinning our cognitive functions ranks highly. The order in which functions are developed or capacities are acquired is a matter of debate between competing psychological theories, and also philosophical conceptions of the mind – getting the role and the significance of the different steps in this order right could be seen as an important virtue of such theories.Thus, a special kind of strategy in arguments between competing philosophical or psychological theories is using developmental order in arguing for or against a given psychological claim. In this article, I will introduce an analysis of arguments from developmental order, which come in two general types: arguments emphasising the importance of the early cognitive processes and arguments emphasising the late cognitive processes. I will discuss their role in one of the central tools for evaluating scientific theories, namely in making inferences to the best explanation. I will argue that appeal to developmental order is, by itself, an insufficient criterion for theory choice and has to be part of an argument based on other core explanatory or empirical virtues. I will end by proposing a more concerted study of philosophical issues concerning (cognitive development, and I will present some topics that also pertain to a full-fledged ‘philosophy of development’.

  17. DOE-2 basics

    Energy Technology Data Exchange (ETDEWEB)

    1991-08-01

    DOE-2 provides the building design and research communities with an up-to-date, unbiased, well-documented public-domain computer program for building energy analysis. DOE-2 predicts the hourly energy use and energy cost of a building given hourly weather information and a description of the building and its HVAC equipment and utility rate structure. DOE-2 is a portable FORTRAN program that can be used on a large variety of computers, including PC's. Using DOE-2, designers can determine the choice of building parameters that improve energy efficiency while maintaining thermal comfort. The purpose of DOE-2 is to aid in the analysis of energy usage in buildings; it is not intended to be the sole source of information relied upon for the design of buildings. The judgment and experience of the architect/engineer still remain the most important elements of building design.

  18. DOE-2 basics

    Energy Technology Data Exchange (ETDEWEB)

    1991-08-01

    DOE-2 provides the building design and research communities with an up-to-date, unbiased, well-documented public-domain computer program for building energy analysis. DOE-2 predicts the hourly energy use and energy cost of a building given hourly weather information and a description of the building and its HVAC equipment and utility rate structure. DOE-2 is a portable FORTRAN program that can be used on a large variety of computers, including PC`s. Using DOE-2, designers can determine the choice of building parameters that improve energy efficiency while maintaining thermal comfort. The purpose of DOE-2 is to aid in the analysis of energy usage in buildings; it is not intended to be the sole source of information relied upon for the design of buildings. The judgment and experience of the architect/engineer still remain the most important elements of building design.

  19. DOE Hazardous Waste Program

    International Nuclear Information System (INIS)

    Eyman, L.D.; Craig, R.B.

    1985-01-01

    The goal of the DOE Hazardous Waste Program is to support the implementation and improvement of hazardous-chemical and mixed-radioactive-waste management such that public health, safety, and the environment are protected and DOE missions are effectively accomplished. The strategy for accomplishing this goal is to define the character and magnitude of hazardous wastes emanating from DOE facilities, determine what DOE resources are available to address these problems, define the regulatory and operational constraints, and develop programs and plans to resolve hazardous waste issues. Over the longer term the program will support the adaptation and application of technologies to meet hazardous waste management needs and to implement an integrated, DOE-wide hazardous waste management strategy. 1 reference, 1 figure

  20. Why does Safety Culture Matter?

    International Nuclear Information System (INIS)

    Dahlgren-Persson, Kerstin

    2008-01-01

    Dr. Kerstin Dahlgren-Persson, from the IAEA presented a plenary paper on 'Why does safety culture matter?'. The paper discussed the main conclusions of a 1998 IAEA conference on shortcomings in safety management. The conference included case studies of TVA, Cooper, Peach Bottom, Millstone, Ontario Hydro, Barsebaeck and Oskarshamn. Common symptoms included insularity; disproportionate focus on technical issues, high initial performance, lack of corporate oversight, changing management direction and cost cutting, repeat problems, and regulatory dissatisfaction. Behind these symptoms was lack of senior utility leadership with the insight, knowledge and ability to manage the unique interaction between the technology, economics, human factors and safety in a changing nuclear environment. Shortcomings relating to the regulator included lack of criteria for when regulatory actions should be taken in response to degradations in safety management, and the inability of some regulators to influence at the senior utility management level. The paper also made the following key points: - Human error is not always symptomatic of a poor safety culture. Effective root cause analysis (such as that carried out for the Columbia accident investigation) is essential to correctly differentiate between situational issues at a point in time and those rooted in organizational culture. - Leaders change culture by holding different assumptions and by making them visible through their words and action. - Regulators should consider how their regulatory strategy influences licensees. For example, a prescriptive strategy can foster a compliance based approach

  1. Pre- and post-natal melatonin administration partially regulates brain oxidative stress but does not improve cognitive or histological alterations in the Ts65Dn mouse model of Down syndrome.

    Science.gov (United States)

    Corrales, Andrea; Parisotto, Eduardo B; Vidal, Verónica; García-Cerro, Susana; Lantigua, Sara; Diego, Marian; Wilhem Filho, Danilo; Sanchez-Barceló, Emilio J; Martínez-Cué, Carmen; Rueda, Noemí

    2017-09-15

    Melatonin administered during adulthood induces beneficial effects on cognition and neuroprotection in the Ts65Dn (TS) mouse model of Down syndrome. Here, we investigated the effects of pre- and post-natal melatonin treatment on behavioral and cognitive abnormalities and on several neuromorphological alterations (hypocellularity, neurogenesis impairment and increased oxidative stress) that appear during the early developmental stages in TS mice. Pregnant TS females were orally treated with melatonin or vehicle from the time of conception until the weaning of the offspring, and the pups continued to receive the treatment from weaning until the age of 5 months. Melatonin administered during the pre- and post-natal periods did not improve the cognitive impairment of TS mice as measured by the Morris Water maze or fear conditioning tests. Histological alterations, such as decreased proliferation (Ki67+ cells) and hippocampal hypocellularity (DAPI+ cells), which are typical in TS mice, were not prevented by melatonin. However, melatonin partially regulated brain oxidative stress by modulating the activity of the primary antioxidant enzymes (superoxide dismutase in the cortex and catalase in the cortex and hippocampus) and slightly decreasing the levels of lipid peroxidation in the hippocampus of TS mice. These results show the inability of melatonin to prevent cognitive impairment in TS mice when it is administered at pre- and post-natal stages. Additionally, our findings suggest that to induce pro-cognitive effects in TS mice during the early stages of development, in addition to attenuating oxidative stress, therapies should aim to improve other altered processes, such as hippocampal neurogenesis and/or hypocellularity. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Nuclear order in copper

    DEFF Research Database (Denmark)

    Annila, A.J.; Clausen, K.N.; Lindgård, P-A.

    1990-01-01

    A new ordering vector k=(2π/a)(0, 2/3, 2/3) for fcc antiferromagnets has been found by neutron-diffraction experiments at nanokelvin temperatures in the nuclear-spin system of a 65Cu single crystal. The corresponding reflection together with the previously observed (100) Bragg peak show the prese......A new ordering vector k=(2π/a)(0, 2/3, 2/3) for fcc antiferromagnets has been found by neutron-diffraction experiments at nanokelvin temperatures in the nuclear-spin system of a 65Cu single crystal. The corresponding reflection together with the previously observed (100) Bragg peak show...

  3. 'Good Order and Police'

    DEFF Research Database (Denmark)

    Mührmann-Lund, Jørgen

    2016-01-01

    The emergence of police ordinances and police authorities in the early modern period has traditionally been seen as a way to discipline society in order to increase the power of the absolutist state. However, recent investigations of early modern policing in German and French regions show...... focused on local needs even after the creation of a royal police office in 1682. Policing mainly concerned the welfare and privileges of burghers in market towns until the introduction of a country police in 1791, when agrarian reforms began to erode the patriarchal order in the countryside. As a new way...

  4. Higher-Order Hierarchies

    DEFF Research Database (Denmark)

    Ernst, Erik

    2003-01-01

    This paper introduces the notion of higher-order inheritance hierarchies. They are useful because they provide well-known benefits of object-orientation at the level of entire hierarchies-benefits which are not available with current approaches. Three facets must be adressed: First, it must be po...

  5. The Ordered Apology

    NARCIS (Netherlands)

    van Dijck, Gijs

    2017-01-01

    Psychological research has demonstrated that an apology can contribute to the well-being of the receiver of the apology. However, the legal community has only cautiously embraced the idea of claiming and ordering apologies in a legal procedure. The conventional wisdom is that apologies that are

  6. Even order snake resonances

    International Nuclear Information System (INIS)

    Lee, S.Y.

    1993-01-01

    We found that the perturbed spin tune due to the imperfection resonance plays an important role in beam depolarization at snake resonances. We also found that even order snake resonances exist in the overlapping intrinsic and imperfection resonances. Due to the perturbed spin tune shift of imperfection resonances, each snake resonance splits into two

  7. On Todorcevic orderings

    Czech Academy of Sciences Publication Activity Database

    Balcar, Bohuslav; Pazák, Tomáš; Thümmel, E.

    2015-01-01

    Roč. 228, č. 2 (2015), s. 173-192 ISSN 0016-2736 Institutional support: RVO:67985840 ; RVO:67985556 Keywords : partial ordering * countable chain condition * forcing Subject RIV: BA - General Mathematics Impact factor: 0.553, year: 2015 http://library.utia.cas.cz/separaty/2015/SI/pazak-0437623.pdf

  8. Birth Order Debate Resolved?

    Science.gov (United States)

    Zajonc, R. B.

    2001-01-01

    Critiques Rodgers et al.'s June 2000 research on the relation between birth order and intelligence, which suggests that it is a methodological illusion. Explains how the intellectual environment and the teaching function (whereby older children tutor younger ones) contribute to the growth of intellectual maturity, the first negatively and the…

  9. Partially ordered models

    NARCIS (Netherlands)

    Fernandez, R.; Deveaux, V.

    2010-01-01

    We provide a formal definition and study the basic properties of partially ordered chains (POC). These systems were proposed to model textures in image processing and to represent independence relations between random variables in statistics (in the later case they are known as Bayesian networks).

  10. Order Division Automated System.

    Science.gov (United States)

    Kniemeyer, Justin M.; And Others

    This publication was prepared by the Order Division Automation Project staff to fulfill the Library of Congress' requirement to document all automation efforts. The report was originally intended for internal use only and not for distribution outside the Library. It is now felt that the library community at-large may have an interest in the…

  11. The Birth Order Puzzle.

    Science.gov (United States)

    Zajonc, R. B.; And Others

    1979-01-01

    Discusses the controversy of the relationship between birth order and intellectual performance through a detailed evaluation of the confluence model which assumes that the rate of intellectual growth is a function of the intellectual environment within the family and associated with the special circumstances of last children. (CM)

  12. The 'final order' problem

    NARCIS (Netherlands)

    Teunter, RH; Haneveld, WKK

    1998-01-01

    When the service department of a company selling machines stops producing and supplying spare parts for certain machines, customers are offered an opportunity to place a so-called final order for these spare parts. We focus on one customer with one machine. The customer plans to use this machine up

  13. Computational fitness landscape for all gene-order permutations of an RNA virus.

    Directory of Open Access Journals (Sweden)

    Kwang-il Lim

    2009-02-01

    Full Text Available How does the growth of a virus depend on the linear arrangement of genes in its genome? Answering this question may enhance our basic understanding of virus evolution and advance applications of viruses as live attenuated vaccines, gene-therapy vectors, or anti-tumor therapeutics. We used a mathematical model for vesicular stomatitis virus (VSV, a prototype RNA virus that encodes five genes (N-P-M-G-L, to simulate the intracellular growth of all 120 possible gene-order variants. Simulated yields of virus infection varied by 6,000-fold and were found to be most sensitive to gene-order permutations that increased levels of the L gene transcript or reduced levels of the N gene transcript, the lowest and highest expressed genes of the wild-type virus, respectively. Effects of gene order on virus growth also depended upon the host-cell environment, reflecting different resources for protein synthesis and different cell susceptibilities to infection. Moreover, by computationally deleting intergenic attenuations, which define a key mechanism of transcriptional regulation in VSV, the variation in growth associated with the 120 gene-order variants was drastically narrowed from 6,000- to 20-fold, and many variants produced higher progeny yields than wild-type. These results suggest that regulation by intergenic attenuation preceded or co-evolved with the fixation of the wild type gene order in the evolution of VSV. In summary, our models have begun to reveal how gene functions, gene regulation, and genomic organization of viruses interact with their host environments to define processes of viral growth and evolution.

  14. The proposed combustion standards and DOE thermal treatment systems

    International Nuclear Information System (INIS)

    McFee, J.; Hinman, M.B.; Eaton, D.; NcNeel, K.

    1997-01-01

    Under the provisions of the Clean Air Act (CAA) concerning emission of hazardous air pollutants (HAPs), the Environmental Protection Agency (EPA) published the proposed Revised Standards for Hazardous Waste Combustors on April 19, 1996 (EPA, 1996). These standards would apply to the existing Department of Energy (DOE) radioactive and mixed waste incinerators, and may be applied to several developing alternatives to incineration. The DOE has reviewed the basis for these regulations and prepared extensive comments to present concerns about the bases and implications of the standards. DOE is now discussing compliance options with the EPA for regulation of radioactive and mixed waste thermal treatment systems

  15. Nuclear safety regulations

    International Nuclear Information System (INIS)

    1998-01-01

    The Departmental Rules and The Safety Guides were issued by the NNSA in 1998. The NNSA performed the activities of propagation and implementation of nuclear safety regulations at QTNPP in order to improve the nuclear safety culture of operating organization and construct and contract organizations

  16. Maintenance and regulations

    International Nuclear Information System (INIS)

    Noel, R.

    1984-01-01

    Description of the main regulations concerning the processes tied with maintenance and in service supervision of the pressure vessels in classical or nuclear power plants or of their accessories (essentially in order to fix the time-table of the hydraulic test procedures and the inspection chronology [fr

  17. Radiation regulation

    International Nuclear Information System (INIS)

    Braithwaite, J.; Grabosky, P.

    1985-01-01

    The five main areas of radiation regulation considered are radiation exposure in the mining of uranium and other minerals, exposure in the use of uranium in nuclear reactors, risks in the transport of radioactive materials and hazards associated with the disposal of used materials. In Australia these problems are regulated by mines departments, the Australian Atomic Energy Commission and radiation control branches in state health departments. Each of these instutional areas of regulation is examined

  18. DOE groundwater protection strategy

    International Nuclear Information System (INIS)

    Lichtman, S.

    1988-01-01

    EH is developing a DOE-wide Groundwater Quality Protection Strategy to express DOE's commitment to the protection of groundwater quality at or near its facilities. This strategy responds to a September 1986 recommendation of the General Accounting Office. It builds on EPA's August 1984 Ground-Water Protection Strategy, which establishes a classification system designed to protect groundwater according to its value and vulnerability. The purposes of DOE's strategy are to highlight groundwater protection as part of current DOE programs and future Departmental planning, to guide DOE managers in developing site-specific groundwater protection practices where DOE has discretion, and to guide DOE's approach to negotiations with EPA/states where regulatory processes apply to groundwater protection at Departmental facilities. The strategy calls for the prevention of groundwater contamination and the cleanup of groundwater commensurate with its usefulness. It would require long-term groundwater protection with reliance on physical rather than institutional control methods. The strategy provides guidance on providing long-term protection of groundwater resources; standards for new remedial actions;guidance on establishing points of compliance; requirements for establishing classification review area; and general guidance on obtaining variances, where applicable, from regulatory requirements. It also outlines management tools to implement this strategy

  19. Guide for effluent radiological measurements at DOE installations

    International Nuclear Information System (INIS)

    Corley, J.P.; Corbit, C.D.

    1983-07-01

    Effluent monitoring and reporting programs are maintained at all US Department of Energy (DOE) facilities that may: (1) discharge significant concentrations of radioactivity in relation to applicable standards, or (2) discharge quantities of radioactivity that have potential health and safety or other environmental significance. This Guide is intended to provide supplemental guidance to DOE Orders on methods, procedures, and performance criteria to bring more comparable rationale to DOE facility effluent measurement programs and promote compliance with applicable standards and provide the DOE Office of Operational Safety (OOS) and Operations Offices with an additional tool for evaluating effluent measurement programs at DOE facilities

  20. 76 FR 62630 - Information Security Regulations

    Science.gov (United States)

    2011-10-11

    ... CENTRAL INTELLIGENCE AGENCY 32 CFR Part 1902 Information Security Regulations AGENCY: Central... information security regulations which have become outdated. The Executive Order upon which the regulations... CFR Part 1902 Information security regulations. PART 1902 [REMOVED AND RESERVED] Sec. 1902.13 [Removed...

  1. 7 CFR 1900.7 - Effect on other regulations.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Effect on other regulations. 1900.7 Section 1900.7 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... REGULATIONS GENERAL Delegations of Authority § 1900.7 Effect on other regulations. This subpart does not...

  2. DOE methods compendium

    International Nuclear Information System (INIS)

    Leasure, C.S.

    1992-01-01

    The Department of Energy (DOE) has established an analytical methods compendium development program to integrate its environmental analytical methods. This program is administered through DOE's Laboratory Management Division (EM-563). The primary objective of this program is to assemble a compendium of analytical chemistry methods of known performance for use by all DOE Environmental Restoration and Waste Management program. This compendium will include methods for sampling, field screening, fixed analytical laboratory and mobile analytical laboratory analyses. It will also include specific guidance on the proper selection of appropriate sampling and analytical methods in using specific analytical requirements

  3. 29 CFR 578.1 - What does this part cover?

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false What does this part cover? 578.1 Section 578.1 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS MINIMUM WAGE... repeatedly or willfully violates the minimum wage (section 6) or overtime provisions (section 7) of the Act...

  4. BLACK HOLE-GALAXY CORRELATIONS WITHOUT SELF-REGULATION

    International Nuclear Information System (INIS)

    Anglés-Alcázar, Daniel; Özel, Feryal; Davé, Romeel

    2013-01-01

    Recent models of black hole growth in a cosmological context have forwarded a paradigm in which the growth is self-regulated by feedback from the black hole itself. Here we use cosmological zoom simulations of galaxy formation down to z = 2 to show that such strong self-regulation is required in the popular spherical Bondi accretion model, but that a plausible alternative model in which black hole growth is limited by galaxy-scale torques does not require self-regulation. Instead, this torque-limited accretion model yields black holes and galaxies evolving on average along the observed scaling relations by relying only on a fixed, 5% mass retention rate onto the black hole from the radius at which the accretion flow is fed. Feedback from the black hole may (and likely does) occur, but does not need to couple to galaxy-scale gas in order to regulate black hole growth. We show that this result is insensitive to variations in the initial black hole mass, stellar feedback, or other implementation details. The torque-limited model allows for high accretion rates at very early epochs (unlike the Bondi case), which if viable can help explain the rapid early growth of black holes, while by z ∼ 2 it yields Eddington factors of ∼1%-10%. This model also yields a less direct correspondence between major merger events and rapid phases of black hole growth. Instead, growth is more closely tied to cosmological disk feeding, which may help explain observational studies showing that, at least at z ∼> 1, active galaxies do not preferentially show merger signatures.

  5. Robert's rules of order

    CERN Document Server

    Robert, Henry M; Balch, Thomas J; Seabold, Daniel E; Gerber, Shmuel

    2011-01-01

    The only authorized edition of the classic work on parliamentary procedure, with new and enhanced features, including how to conduct electronic meetings. Robert's Rules of Order is the book on parliamentary procedure for parliamentarians and anyone involved in an organization, association, club, or group and the authoritative guide to smooth, orderly, and fairly conducted meetings and assemblies. This newly revised edition is the only book on parliamentary procedure to have been updated since 1876 under the continuing program of review established by General Henry M. Robert himself, in cooperation with the official publisher of Robert's Rules. The eleventh edition has been thoroughly revised to address common inquiries and incorporate new rules, interpretations, and procedures made necessary by the evolution of parliamentary procedure, including new material relating to electronic communication and "electronic meetings."

  6. Fragile Thermodynamic Order

    International Nuclear Information System (INIS)

    Bernhoeft, N.; Lander, G.H.; Colineau, E.

    2003-01-01

    An asymmetric shift in the position of the magnetic Bragg peak with respect to the fiducial lattice has been observed by resonant X-ray scattering in a diverse series of antiferromagnetic compounds. This apparent violation of Bragg's law is interpreted in terms of a dynamically phased order parameter. We demonstrate the use of this effect as a novel probe of fragile or dynamic thermodynamic order in strongly correlated electronic systems. In particular, fresh light is shed on the paradoxical situation encountered in URu 2 Si 2 where the measured entropy gain on passing through T Neel is incompatible with the ground state moment estimated by neutron diffraction. The intrinsic space-time averaging of the probe used to characterise the thermodynamic macroscopic state may play a crucial and previously neglected role. In turn, this suggests the further use of resonant X-ray scattering in investigations of systems dominated by quantum fluctuations. (author)

  7. Ordered cones and approximation

    CERN Document Server

    Keimel, Klaus

    1992-01-01

    This book presents a unified approach to Korovkin-type approximation theorems. It includes classical material on the approximation of real-valuedfunctions as well as recent and new results on set-valued functions and stochastic processes, and on weighted approximation. The results are notonly of qualitative nature, but include quantitative bounds on the order of approximation. The book is addressed to researchers in functional analysis and approximation theory as well as to those that want to applythese methods in other fields. It is largely self- contained, but the readershould have a solid background in abstract functional analysis. The unified approach is based on a new notion of locally convex ordered cones that are not embeddable in vector spaces but allow Hahn-Banach type separation and extension theorems. This concept seems to be of independent interest.

  8. Ordering in classical Coulombic systems

    International Nuclear Information System (INIS)

    Schiffer, J. P.

    1998-01-01

    The author discusses the properties of classical Coulombic matter at low temperatures. It has been well known for some time [1,2] that infinite Coulombic matter will crystallize in body-centered cubic form when the quantity Λ (the dimensionless ratio of the average two-particle Coulomb energy to the kinetic energy per particle) is larger than approximately175. But the systems of such particles that have been produced in the laboratory in ion traps, or ion beams, are finite with surfaces defined by the boundary conditions that have to be satisfied. This results in ion clouds with sharply defined curved surfaces, and interior structures that show up as a set of concentric layers that are parallel to the outer surface. The ordering does not appear to be cubic, but the charges on each shell exhibit a ''hexatic'' pattern of equilateral triangles that is the characteristic of liquid crystals. The curvature of the surfaces prevents the structures on successive shells from interlocking in any simple fashion. This class of structures was first found in simulations [3] and later in experiments [4

  9. Are Limit Orders Rational?

    Czech Academy of Sciences Publication Activity Database

    Šmíd, Martin

    2007-01-01

    Roč. 14, č. 4 (2007), s. 32-38 ISSN 0572-3043 R&D Projects: GA ČR(CZ) GA402/06/1417; GA ČR GA402/04/1294; GA ČR GD402/03/H057 Institutional research plan: CEZ:AV0Z10750506 Keywords : market microstructure * limit order market * portfolio selection Subject RIV: AH - Economics

  10. Birth Order and Psychopathology

    OpenAIRE

    Risal, Ajay; Tharoor, Hema

    2012-01-01

    Context: Ordinal position the child holds within the sibling ranking of a family is related to intellectual functioning, personality, behavior, and development of psychopathology. Aim: To study the association between birth order and development of psychopathology in patients attending psychiatry services in a teaching hospital. Settings and Design: Hospital-based cross-sectional study. Materials and Methods: Retrospective file review of three groups of patients was carried out. Patient-relat...

  11. Testing hypotheses in order

    OpenAIRE

    Paul R. Rosenbaum

    2008-01-01

    In certain circumstances, one wishes to test one hypothesis only if certain other hypotheses have been rejected. This ordering of hypotheses simplifies the task of controlling the probability of rejecting any true hypothesis. In an example from an observational study, a treated group is shown to be further from both of two control groups than the two control groups are from each other. Copyright 2008, Oxford University Press.

  12. Hierarchical partial order ranking

    International Nuclear Information System (INIS)

    Carlsen, Lars

    2008-01-01

    Assessing the potential impact on environmental and human health from the production and use of chemicals or from polluted sites involves a multi-criteria evaluation scheme. A priori several parameters are to address, e.g., production tonnage, specific release scenarios, geographical and site-specific factors in addition to various substance dependent parameters. Further socio-economic factors may be taken into consideration. The number of parameters to be included may well appear to be prohibitive for developing a sensible model. The study introduces hierarchical partial order ranking (HPOR) that remedies this problem. By HPOR the original parameters are initially grouped based on their mutual connection and a set of meta-descriptors is derived representing the ranking corresponding to the single groups of descriptors, respectively. A second partial order ranking is carried out based on the meta-descriptors, the final ranking being disclosed though average ranks. An illustrative example on the prioritisation of polluted sites is given. - Hierarchical partial order ranking of polluted sites has been developed for prioritization based on a large number of parameters

  13. Fourteenth annual report radiation exposures for DOE and DOE contractor employees - 1981

    International Nuclear Information System (INIS)

    1983-03-01

    All Department of Energy (DOE) and DOE contractors are required by DOE Order 5484.1, Chapter IV, to submit occupational exposure records to a central repository. The data required includes a summary of whole-body exposures to ionizing radiation, a summary of internal depositions of radioactive materials above specified limits, and occupational exposure reports for terminating employees. This report is a summary of the data submitted by DOE and DOE contractors for 1981. A total of 82,873 DOE and DOE contractor employees were monitored for whole-body ionizing radiation exposures in 1981. In addition to the employees, 84,343 visitors were monitored. Of all employees monitored, 54.43% received a dose equivalent that was less than measurable, 44.04% a measurable exposure less than 1 rem, and 1.53% an exposure granter than 1 rem. the exposure received by 88.14% of the visitors to DOE facilities was less than measurable. Only 11.85% of the visitors received a measurable exposure less than 1 rem, and 0.0% of the visitors received an exposure greater than 1 rem. No employees or visitors received a dose equivalent greater than 5 rem. The collective dose equivalent for DOE and DOE contractors employees was 6,902 person-rem. The collective dose equivalent for visitors was 579 person-rem. The total dose equivalent for employees and visitors combined was 7,481 person-rem. The average dose equivalent for all individuals (employees and visitors) monitored was 45 mrem and the average dose equivalent for all individuals who received a measurable exposure was 157 mrem. The highest average dose equivalent was observed for employees monitored at fuel processing facilities (342 mrem) and the lowest among visitors (7 mrem) to DOE facilities. These averages are significantly less than the DOE 5-rem/year radiation protection standard for whole-body exposures

  14. DOE Robotics Project

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    This document provide the bimonthly progress reports on the Department of Energy (DOE) Robotics Project by the University of Michigan. Reports are provided for the time periods of December 90/January 91 through June 91/July 91. (FI)

  15. The Nordic Model in a Global Company Situated in Norway. Challenging Institutional Orders?

    Directory of Open Access Journals (Sweden)

    Elin Kvande

    2012-11-01

    Full Text Available In this article, we explore the impact of internationalization as organizational processes where institutional actors meet in local contexts and negotiate the institutional order. The internationalization of working life implies that different traditions and practices meet and challenge each other. The focus is on how important elements of the Nordic micro model like cooperation between employees and employers and regulation of working hours are implemented in a global company situated in Norway. In general, it seems that employees and employers cooperate in line with this tradition in the Nordic micro model. Norwegian manager’s practices are described to be in accordance with Scandinavian management traditions, while managers from the United States appear to practice management consistent with the liberal working life model. The findings show a tension-filled clash between two different management practices, which indicates that the Nordic micro model in this field might be under pressure. Manager’s recommendation to the employees was not to become members of the trade union. The absence of trade unions in the organization implies that employees and employers are not cooperating on a collective level. This means that only parts of the regulatory arrangement related to participation and cooperation are implemented. Findings concerning working time and the relation to the institutional order represented by the Norwegian Work Environment Act indicate a clear tension between different institutional traditions in the organization. The company does not respect the Norwegian in working time regulations. These regulations are seen as counterproductive for a company that competes in the international market. This devaluation of the regulations in the Nordic model implies that the institutional order represented in the Nordic micro model is challenged.

  16. 48 CFR 52.243-6 - Change Order Accounting.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Change Order Accounting....243-6 Change Order Accounting. As prescribed in 43.205(f), the contracting officer may insert a clause, substantially the same as follows: Change Order Accounting (APR 1984) The Contracting Officer may require change...

  17. 48 CFR 43.203 - Change order accounting procedures.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Change order accounting... CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders 43.203 Change order accounting procedures. (a) Contractors' accounting systems are seldom designed to segregate the costs of performing changed work...

  18. Regulatory decision with EPA/NRC/DOE/State Session (Panel)

    Energy Technology Data Exchange (ETDEWEB)

    O`Donnell, E.

    1995-12-31

    This panel will cover the Nuclear Regulatory Commission`s (NRC) proposed radiation limits in the Branch Technical Position on Low-Level Radioactive Waste Performance Assessment and the Environmental Protection Agency`s (EPA) draft regulation in Part 193. Representatives from NRC and EPA will discuss the inconsistencies in these two regulations. DOE and state representatives will discuss their perspective on how these regulations will affect low-level radioactive waste performance assessments.

  19. Fractional Order Generalized Information

    Directory of Open Access Journals (Sweden)

    José Tenreiro Machado

    2014-04-01

    Full Text Available This paper formulates a novel expression for entropy inspired in the properties of Fractional Calculus. The characteristics of the generalized fractional entropy are tested both in standard probability distributions and real world data series. The results reveal that tuning the fractional order allow an high sensitivity to the signal evolution, which is useful in describing the dynamics of complex systems. The concepts are also extended to relative distances and tested with several sets of data, confirming the goodness of the generalization.

  20. Partially ordered algebraic systems

    CERN Document Server

    Fuchs, Laszlo

    2011-01-01

    Originally published in an important series of books on pure and applied mathematics, this monograph by a distinguished mathematician explores a high-level area in algebra. It constitutes the first systematic summary of research concerning partially ordered groups, semigroups, rings, and fields. The self-contained treatment features numerous problems, complete proofs, a detailed bibliography, and indexes. It presumes some knowledge of abstract algebra, providing necessary background and references where appropriate. This inexpensive edition of a hard-to-find systematic survey will fill a gap i

  1. Ordering, materiality and multiplicity

    DEFF Research Database (Denmark)

    van der Duim, René; Ren, Carina Bregnholm; Jóhannesson, Gunnar Thór

    2013-01-01

    In this article we discuss how ANT has been translated into tourism research and show how it has impacted the field by presenting three concepts integral to the ANT approach: ordering, materiality and multiplicity. We first introduce ANT and draw attention to current ANT studies in tourism......, followed by a discussion of how newer approaches within post-ANT urge us to face the ontological politics, which we engage in when performing tourism research. In conclusion we argue that ANT enables a radical new way at looking at tourism, tourism destinations and objects and investigations...... into the ontological condition of tourism....

  2. Deceptive Business Practices: Federal Regulations.

    Science.gov (United States)

    Rohrer, Daniel Morgan

    Federal regulations to prevent deceptive advertising seek to balance the advertiser's freedom of speech with protection of the consumer. This paper discusses what the Federal Trade Commission (FTC) has done to regulate advertising and evaluates the adequacy of its controls. The commission uses cease-and-desist orders, affirmative disclosure,…

  3. Meeting the requirements for a DOE environmental restoration project. The Fernald strategy

    International Nuclear Information System (INIS)

    Vanoss, R.L.; Risenhoover, G.M.

    1994-01-01

    Environmental Restoration (ER) of five Operable Units (OU) at Fernald Environmental Management Project (FEMP) includes compliance with the requirements of Comprehensive Environmental Response, Compensation and Liability Act (CERCLA), Resource Conservation Recovery Act (RCRA), National Environmental Policy Act (NEPA), and DOE Orders. Each regulatory driver has differing procedural requirements for documenting calculations, decisions, and actions involved in site cleanup. Integration of documentation and avoidance of duplication can save time and money. Such savings are being achieved by OU specific application of supporting studies, revised procedures, and guidance documents. Each OU is seeking appropriate opportunities to produce single documents that simultaneously fulfill the important requirements of the other regulations and DOE orders. These opportunities are evaluated at all phases of decision making, remedial design, and remedial action. Three essential processes precede environmental restoration/remedial action at a DOE site/project: 1. Completion of decision-making documents required by governing or applicable statutes. 2. Completion of important scientific and engineering analyses of remedial alternatives, and design and implementation of the remedial solution established in the CERCLA Record of Decision (ROD). 3. Preparation of DOE-mandated documentation to record engineering evaluations and cost estimates required for budgeting, decision making, and project management. Methodology and requirements for each process have developed from long, successful practice, but independently of each other. FERMCO, as new DOE contractor at Fernald and first Environmental Restoration Management Contractor (ERMC), is committed to a process of Continuous Performance Improvement (CPI). A major reevaluation of documentation and processes for support of environmental decision-making and design of cleanup activities to remediate the five OUs at the FEMP is being undertaken

  4. 78 FR 35195 - Acquisition Regulations: Export Control

    Science.gov (United States)

    2013-06-12

    ... DEPARTMENT OF ENERGY 48 CFR Parts 925, 952, and 970 RIN 1991-AB99 Acquisition Regulations: Export... Energy (DOE) is proposing to amend the Department of Energy Acquisition Regulation (DEAR) to add export... comments, identified by ``DEAR: Export Control and RIN 1991-AB99,'' by any of the following methods...

  5. Ordered photonic microstructures

    Science.gov (United States)

    Chen, Kevin Ming

    2001-09-01

    This thesis examines novel photonic materials systems possessing order in the atomic, microscopic, and macroscopic dimensional regimes. In the atomic order regime, a structure-property investigation is done for Er2O3 in which the first report of room temperature photoluminescence (PL) is provided. Thin films of the rare earth oxide were deposited via reactive sputtering of Er metal in an Ar/O2 ambient, and subsequently annealed to promote grain growth. Heat treatment consisting of a 650°C followed by 1000°C anneal produces maximum crystallinity as measured by glancing angle x-ray diffraction. These films show characteristic PL at λ = 1.54 μm. In the microscopic order regime, omnidirectional reflectors and thin film microcavities are demonstrated using sol-gel and solid-state materials. A first demonstration of omnidirectional reflectivity in sol-gel structures was accomplished using a dielectric stack consisting of 12 spin-on SiO 2/TiO2 quarterwave sol-gel films. Similarly, solid-state dielectric stacks consisting of 6 Si/SiO2 sputtered films were used to demonstrate the same principle. Microcavities were formed using solgel structures, producing a low quality factor Q = 35 due to limitations in film thickness control and lossy interfaces from stress-induced cracks. The high index contrast Si/SiO2 microcavities enabled Q ~ 1000 using 17 total layers following hydrogenation of dangling bonds within the amorphous Si films. Combining fabrication processes for the solid-state microcavity and Er2O3 films, a device was fabricated to demonstrate photoluminescence enhancement of an Er2O3 film embedded in a microcavity. The structure consisted of 3-bilayer mirrors on either side of an SiO2/Er2O3/SiO2 cavity. The Q ~ 300 was near the theoretical value for such a structure. At room temperature, PL of Er2O3 was enhanced by a factor of 1000 in the microcavity compared to a single thin film. In the macroscopic order regime, self-assembly of micron- sized SiO 2 and

  6. Strategic parenting, birth order, and school performance.

    Science.gov (United States)

    Hotz, V Joseph; Pantano, Juan

    2015-10-01

    Fueled by new evidence, there has been renewed interest about the effects of birth order on human capital accumulation. The underlying causal mechanisms for such effects remain unsettled. We consider a model in which parents impose more stringent disciplinary environments in response to their earlier-born children's poor performance in school in order to deter such outcomes for their later-born offspring. We provide robust empirical evidence that school performance of children in the National Longitudinal Study Children (NLSY-C) declines with birth order as does the stringency of their parents' disciplinary restrictions. When asked how they will respond if a child brought home bad grades, parents state that they would be less likely to punish their later-born children. Taken together, these patterns are consistent with a reputation model of strategic parenting.

  7. A DOE Perspective

    Science.gov (United States)

    Bennett, Kristin

    2004-03-01

    As one of the lead agencies for nanotechnology research and development, the Department of Energy (DOE) is revolutionizing the way we understand and manipulate materials at the nanoscale. As the Federal government's single largest supporter of basic research in the physical sciences in the United States, and overseeing the Nation's cross-cutting research programs in high-energy physics, nuclear physics, and fusion energy sciences, the DOE guides the grand challenges in nanomaterials research that will have an impact on everything from medicine, to energy production, to manufacturing. Within the DOE's Office of Science, the Office of Basic Energy Sciences (BES) leads research and development at the nanoscale, which supports the Department's missions of national security, energy, science, and the environment. The cornerstone of the program in nanoscience is the establishment and operation of five new Nanoscale Science Research Centers (NSRCs), which are under development at six DOE Laboratories. Throughout its history, DOE's Office of Science has designed, constructed and operated many of the nation's most advanced, large-scale research and development user facilities, of importance to all areas of science. These state-of-the art facilities are shared with the science community worldwide and contain technologies and instruments that are available nowhere else. Like all DOE national user facilities, the new NSRCs are designed to make novel state-of-the-art research tools available to the world, and to accelerate a broad scale national effort in basic nanoscience and nanotechnology. The NSRCs will be sited adjacent to or near existing DOE/BES major user facilities, and are designed to enable national user access to world-class capabilities for the synthesis, processing, fabrication, and analysis of materials at the nanoscale, and to transform the nation's approach to nanomaterials.

  8. Procedure for Prioritization of Natural Phenomena Hazards Evaluations for Existing DOE Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Conrads, T.J., Westinghouse Hanford

    1996-05-07

    This document describes the procedure to be used for the prioritization for natural phenomena hazards evaluations of existing DOE facilities in conformance with DOE Order 5480.28, `Natural Phenomena Hazards Mitigation.`

  9. Use of experience data for DOE seismic evaluations

    International Nuclear Information System (INIS)

    Barlow, M.W.; Budnitz, R.; Eder, S.J.; Eli, M.W.

    1993-01-01

    As dictated by DOE Order 5480.28, seismic evaluations of essential systems and components at DOE facilities will be conducted over the next several years. For many of these systems and components, few, if any, seismic requirements applied to the original design, procurement, installation, and maintenance process. Thus the verification of the seismic adequacy of existing systems and components presents a difficult challenge. DOE has undertaken development of the criteria and procedures for these seismic evaluations that will maximize safety benefits in a timely and cost effective manner. As demonstrated in previous applications at DOE facilities and by the experience from the commercial nuclear power industry, use of experience data for these evaluations is the only viable option for most existing systems and components. This paper describes seismic experience data, the needs at DOE facilities, the precedent of application at nuclear power plants and DOE facilities, and the program being put in place for the seismic verification task ahead for DOE

  10. 48 CFR 952.219-70 - DOE Mentor-Protege program.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false DOE Mentor-Protege program... FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 952.219-70 DOE Mentor.... DOE Mentor-Protege Program (MAY 2000) The Department of Energy has established a Mentor-Protege...

  11. 76 FR 33967 - Irish Potatoes Grown in Southeastern States; Suspension of Marketing Order Provisions

    Science.gov (United States)

    2011-06-10

    ... IR] Irish Potatoes Grown in Southeastern States; Suspension of Marketing Order Provisions AGENCY... suspends the marketing order for Irish potatoes grown in Southeastern states (order), and the rules and regulations implemented thereunder, through March 1, 2014. The order regulates the handling of Irish potatoes...

  12. The Emerging World Order

    Directory of Open Access Journals (Sweden)

    PETER COLLECOTT

    2014-05-01

    Full Text Available It is common ground amongst almost all commentators that the world has changed radically over the past 25 years – the 25 years since the fall of the Berlin Wall heralded the ending of the Cold War, the reunification of a tragically divided Europe, and the acceleration of the process of globalisation which has its only comparable period in the decades leading up to the First World War in 1914. When analyzing the Emerging World Order it is important to cover more than Brazil economy or any other individual BRICs or other Emerging Powers. Instead, our analysis will provide a global view about the economic and political global power structures which are evolving and forming before our eyes, and then to talk about the challenges these emerging realities pose for us in Europe, and in the West in general.

  13. The new Wuergassen order

    International Nuclear Information System (INIS)

    Anon.

    1975-01-01

    In the contentious administrative matter concerning the contestation of several partial licenses for the Wuergassen nuclear power station, the Supreme Court of Administration for Nordrhein-Westfalen, has also dismissed the appeal of the plaintiff from the dismissal of the action delivered by the Minden administrative court. The order was passed on 20th February, 1975 - VII A 911/69 - and agrees with the dismissal by the Federal Administrative Court. The plaintiff was a private person. The defendants were the licensing authorities, the Minister for Economy, and the Minister fuer Wirtschaft, Mittelstand und Verkehr of Nordrhein-Westfalen. Also summoned was the Preussische Elektrizitaets-AG, Hannover, to whom the contested licenses had been issued. The value in litigation was fixed at DM 10,000. One half of the extra-judicial costs of the summoned was declared repayable. Some of the grounds upon which the judgment was based are presented in detail. (orig./AK) [de

  14. Higher Order Mode Fibers

    DEFF Research Database (Denmark)

    Israelsen, Stine Møller

    This PhD thesis considers higher order modes (HOMs) in optical fibers. That includes their excitation and characteristics. Within the last decades, HOMs have been applied both for space multiplexing in optical communications, group velocity dispersion management and sensing among others......-radial polarization as opposed to the linear polarization of the LP0X modes. The effect is investigated numerically in a double cladding fiber with an outer aircladding using a full vectorial modesolver. Experimentally, the bowtie modes are excited using a long period grating and their free space characteristics...... and polarization state are investigated. For this fiber, the onset of the bowtie effect is shown numerically to be LP011. The characteristics usually associated with Bessel-likes modes such as long diffraction free length and selfhealing are shown to be conserved despite the lack of azimuthal symmetry...

  15. Birth order and myopia.

    Science.gov (United States)

    Guggenheim, Jeremy A; McMahon, George; Northstone, Kate; Mandel, Yossi; Kaiserman, Igor; Stone, Richard A; Lin, Xiaoyu; Saw, Seang Mei; Forward, Hannah; Mackey, David A; Yazar, Seyhan; Young, Terri L; Williams, Cathy

    2013-12-01

    An association between birth order and reduced unaided vision (a surrogate for myopia) has been observed previously. We examined the association between birth order and myopia directly in four subject groups. Subject groups were participants in (1) the Avon Longitudinal Study of Parents and Children (ALSPAC; UK; age 15 years; N = 4401), (2) the Singapore Cohort Study of Risk Factors for Myopia (SCORM; Singapore; age 13 years; N = 1959), (3) the Raine Eye Health Study (REHS; Australia; age 20 years; N = 1344), and (4) Israeli Defense Force Pre-recruitment Candidates (IDFC; Israel; age 16-22 years; N = 888,277). The main outcome was odds ratios (OR) for myopia in first-born versus non-first-born individuals after adjusting for potential risk factors. The prevalence of myopia was numerically higher in first-born versus non-first-born individuals in all study groups, but the strength of evidence varied widely. Adjusted ORs (95% confidence intervals, CIs) were: ALSPAC, 1.31 (1.05-1.64); SCORM, 1.25 (0.89-1.77); REHS, 1.18 (0.90-1.55); and IDFC, 1.04 (1.03-1.06). In the large IDFC sample, the effect size was greater (a) for the first-born versus fourth- or higher-born comparison than for the first-born versus second/third-born comparison (p 4000 participants provided strong statistical support for the association. The available evidence suggested the relationship was independent of established risk factors such as time outdoors/reading, and thus may arise through a different causal mechanism.

  16. Site characterization criteria (DOE-STD-1022-94) for natural phenomena hazards at DOE sites

    International Nuclear Information System (INIS)

    Chen, J.C.; Ueng, T.S.; Boissonnade, A.C.

    1995-12-01

    This paper briefly summarizes requirements of site characterization for Natural Phenomena Hazards (NPH) at DOE sites. In order to comply with DOE Order 5480.28, site characterization criteria has been developed to provide site-specific information needed for development of NPH assessment criteria. Appropriate approaches are outlined to ensure that the current state-of-the-art methodologies and procedures are used in the site characterization. General and detailed site characterization requirements are provided in the areas of meteorology, hydrology, geology, seismology and geotechnical studies

  17. Incentive-based regulation of CO2 emissions from international aviation

    International Nuclear Information System (INIS)

    Carlsson, F.; Hammar, H.

    2002-01-01

    We explore the possibilities of using incentive-based environmental regulations of CO 2 emissions from international civil aviation. In theory incentive-based instruments such as an emission charge or a tradable emission permit system are better regulations than so-called command-and-control regulations such as emission limits or technology standards. However, the implementation of these instruments is a complex issue. We therefore describe and discuss how an emission charge and a tradable emission permit system for international aviation should be designed in order to improve efficiency. We also compare these two types of regulations. In brief, we find that an emission charge and a tradable emission permit system in which the permits are auctioned have more or less the same characteristics. The main advantage of a tradable emission permit system is that the effect, in terms of emission reductions, is known. On the other hand, we show that under uncertainty an emission charge is preferred. The choice of regulation is a political decision and it does not seem likely that an environmental charge or a tradable emission permit system would be implemented without consideration of the costs of the regulation. Revenue-neutral charges or gratis distribution of permits would, for this reason, be realistic choices of regulations. However, such actions are likely to result in less stringent regulations and other negative welfare effects.(author)

  18. Nil Bohr-sets and almost automorphy of higher order

    CERN Document Server

    Huang, Wen; Ye, Xiangdong

    2016-01-01

    Two closely related topics, higher order Bohr sets and higher order almost automorphy, are investigated in this paper. Both of them are related to nilsystems. In the first part, the problem which can be viewed as the higher order version of an old question concerning Bohr sets is studied: for any d\\in \\mathbb{N} does the collection of \\{n\\in \\mathbb{Z}: S\\cap (S-n)\\cap\\ldots\\cap (S-dn)\

  19. 29 CFR 570.67 - Occupations in roofing operations and on or about a roof (Order 16).

    Science.gov (United States)

    2010-07-01

    ..., DEPARTMENT OF LABOR REGULATIONS CHILD LABOR REGULATIONS, ORDERS AND STATEMENTS OF INTERPRETATION Occupations... servicing of television and communication equipment such as cable and satellite dishes; the installation and...

  20. Second DOE natural phenomena hazards mitigation conference

    International Nuclear Information System (INIS)

    1989-01-01

    This conference has been organized into ten presentation sessions which include an overview of the DOE Natural Phenomena Guidelines, Seismic Analysis, Seismic Design, Modifying Existing Facilities, DOE Orders, Codes, and Standards (2 sessions), Seismic Hazard (2 sessions), and Probabilistic Risk Assessment (2 sessions). Two poster sessions were also included in the program to provide a different forum for communication of ideas. Over the past fourteen years, Lawrence Livermore National Laboratory, Nuclear Systems Safety Program, has been working with the US Department of Energy, Office of Safety Appraisals and their predecessors in the area of natural phenomena hazards. During this time we have developed seismic, extreme wind/tornado, and flood hazard models for DOE sites in the United States. Guidelines for designing and evaluating DOE facilities for natural phenomena have been developed and are in interim use throughout the DOE community. A series of state-of-the practice manuals have also been developed to aid the designers. All of this material is listed in the Natural Phenomena Hazards Bibliography included in these proceedings. This conference provides a mechanism to disseminate current information on natural phenomena hazards and their mitigation. It provides an opportunity to bring together members of the DOE community to discuss current projects, to share information, and to hear practicing members of the structural engineering community discuss their experiences from past natural phenomena, future trends, and any changes to building codes. Each paper or poster presented is included in these proceedings. We have also included material related to the luncheon and dinner talks

  1. Reproductive activity and welfare of rabbit does

    Directory of Open Access Journals (Sweden)

    C. Castellini

    2010-04-01

    Full Text Available This paper reviews the relationships between reproductive performance and welfare of the rabbit does. In the last 10 years the profitability of rabbit farms has increased mainly due to improvements in management and genetic selection but several problems mainly related to animal welfare have also occurred. The mortality and rates of female replacement per year are very high and the replaced females often show poor body condition and low performance. The effect of kindling order, litter size, genetic strain, weaning age and reproduction rhythm on the reproductive performance and welfare of females and some mechanisms implicated in these effects are discussed. Modern rabbit does produce a lot of milk which have a high energetic value which leads to a mobilization of body fat which results in an energy deficit. In the current reproductive rhythms, there is an extensive overlap between lactation and gestation. The resulting energetic and hormonal antagonism reduces the fertility rate and lifespan of the doe. Strategies to improve the fertility, lifespan and welfare of does are discussed. An approach which combines various strategies seems to be required to meet these objectives. Since the factors involved in this productive system are fixed (genetic strain, environment the most powerful way to improve doe welfare is to choose a reproductive rhythm that is adapted to the physiology of the does.

  2. DOE headquarters publications

    International Nuclear Information System (INIS)

    1978-09-01

    This bibliography provides listings of (mainly policy and programmatic) publications issued from the U.S. Department of Energy, Washington, D.C. The listings are arranged by the ''report code'' assigned to each of the major organizations at DOE Headquarters, followed by the three categories of environmental reports issued from DOE Headquarters. All of the publications listed, except for those shown as still ''in preparation,'' may be seen in the Energy Library. A title index arranged by title keywords follows the listings. Certain publications are omitted. They include such items as pamphlets, ''fact sheets,'' bulletins and weekly/monthly issuances of DOE's Energy Information Administration and Economic Regulatory Administration, and employee bulletins and newsletters. Omitted from the bibliography altogether are headquarters publications assigned other types of report codes--e.g., ''HCP'' (Headquarters Contractor Publication) and ''CONF'' (conference proceedings)

  3. DOE goals: Excellence, openness

    International Nuclear Information System (INIS)

    Isaacs, T.H.

    1989-01-01

    The author feels that the benefit of the experience and programmatic resources it has developed since passage of the Nuclear Waste Policy Act in 1982 and of the sound and flexible policy framework provided by the amendments, DOE is confident that program objectives can be met on a schedule that balances the needs for technical excellence, institutional openness, and timely acceptance. As the program evolves, DOE will continue to assess how effectively policies are serving program objectives. The need for flexibility in developing a first-of-a-kind system is essential. But flexibility does not alter the need for program stability, which, in turn, requires a commonly shared commitment to realizing the program's goals. This commitment must rest upon a pragmatic understanding of the realities of waste-management system development

  4. Thermally assisted ordering in Mott insulators

    Science.gov (United States)

    Sims, Hunter; Pavarini, Eva; Koch, Erik

    2017-08-01

    Landau theory describes phase transitions as the competition between energy and entropy: The ordered phase has lower energy, while the disordered phase has larger entropy. When heating the system, ordering is reduced entropically until it vanishes at the critical temperature. This picture implicitly assumes that the energy difference between the ordered and disordered phases does not change with temperature. We show that for orbital ordering in the Mott insulator KCuF3, this assumption fails qualitatively: entropy plays a negligible role, while thermal expansion energetically stabilizes the orbitally ordered phase to such an extent that no phase transition is observed. To understand this strong dependence on the lattice constant, we need to take into account the Born-Mayer repulsion between the ions. It is the latter, and not the Jahn-Teller elastic energy, which determines the magnitude of the distortion. This effect will be seen in all materials where the distortion expected from the Jahn-Teller mechanism is so large that the ions would touch. Our mechanism explains not only the absence of a phase transition in KCuF3, but even suggests the possibility of an inverted transition in closed-shell systems, where the ordered phase emerges only at high temperatures.

  5. Third DOE natural phenomena hazards mitigation conference

    International Nuclear Information System (INIS)

    1991-01-01

    This conference on Natural Phenomena Hazards Mitigation has been organized into 15 presentation, panel, and poster sessions. The sessions included an overview of activities at DOE Headquarters; natural phenomena hazards tasks underway for DOE; two sessions on codes, standards, orders, criteria, and guidelines; two sessions on seismic hazards; equipment qualification; wind; PRA and margin assessments; modifications, retrofit, and restart; underground structures with a panel discussion; seismic analysis; seismic evaluation and design; and a poster session. Individual projects are processed separately for the data bases

  6. Recursive belief manipulation and second-order false-beliefs

    DEFF Research Database (Denmark)

    Braüner, Torben; Blackburn, Patrick Rowan; Polyanskaya, Irina

    2016-01-01

    it indicate that a more fundamental *conceptual change* has taken place? In this paper we extend Braüner's hybrid-logical analysis of first-order false-belief tasks to the second-order case, and argue that our analysis supports a version of the conceptual change position.......The literature on first-order false-belief is extensive, but less is known about the second-order case. The ability to handle second-order false-beliefs correctly seems to mark a cognitively significant step, but what is its status? Is it an example of *complexity only* development, or does...

  7. Does immunity regulate ejaculate quality and fertility in humans?

    OpenAIRE

    Philip A. Skau; Ivar Folstad

    2005-01-01

    The production of high-quality ejaculates may represent significant costs during male reproduction. Spermatozoa are perceived as nonself by the immune system and are exposed to immunological attacks in the male reproductive tract. Autoimmunity to spermatozoa results in the production of antisperm antibodies that reduce sperm quality and hence fertility. Thus, males are dependent on the testis being an immunoprivileged site to reduce immunological reactions against their own sperm, and immunop...

  8. Does Apoptosis Regulate the Function of Retinal Photoreceptors?

    OpenAIRE

    Halaby, Reginald

    2012-01-01

    Apoptosis, or programmed cell death, is an integral component of developmental biology, embryology, and anatomy. All eukaryotic cells possess the molecular machinery necessary to execute apoptosis. However, dysregulated apoptosis in the form of too much or too little cell death results in diseases such as Alzheimer’s disease, autoimmune disorders, and cancer. It is postulated that apoptosis of the photoreceptors in the retina plays a vital role in mediating vision, and evidence is presented h...

  9. 15 CFR 700.12 - Elements of a rated order.

    Science.gov (United States)

    2010-01-01

    ...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE NATIONAL SECURITY INDUSTRIAL BASE REGULATIONS DEFENSE PRIORITIES AND ALLOCATIONS SYSTEM Industrial Priorities § 700.12 Elements of a rated order. Each...

  10. 15 CFR 700.17 - Use of rated orders.

    Science.gov (United States)

    2010-01-01

    ...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE NATIONAL SECURITY INDUSTRIAL BASE REGULATIONS DEFENSE PRIORITIES AND ALLOCATIONS SYSTEM Industrial Priorities § 700.17 Use of rated orders. (a) A person...

  11. Deciphering Transcriptional Regulation

    DEFF Research Database (Denmark)

    Valen, Eivind

    The myriad of cells in the human body are all made from the same blueprint: the human genome. At the heart of this diversity lies the concept of gene regulation, the process in which it is decided which genes are used where and when. Genes do not function as on/off buttons, but more like a volume...... mostly near the start of the gene known as the promoter. This region contains patterns scattered in the DNA that the TFs can recognize and bind to. Such binding can prompt the assembly of the pre-initiation complex which ultimately leads to transcription of the gene. In order to achieve the regulation...... on what characterizes a hippocampus promoter. Pairing CAGE with TF binding site prediction we identi¿ed a likely key regulator of hippocampus. Finally, we developed a method for CAGE exploration. While the DeepCAGE library characterized a full 1.4 million transcription initiation events it did not capture...

  12. First order correction to quasiclassical scattering amplitude

    International Nuclear Information System (INIS)

    Kuz'menko, A.V.

    1978-01-01

    First order (with respect to h) correction to quasiclassical with the aid of scattering amplitude in nonrelativistic quantum mechanics is considered. This correction is represented by two-loop diagrams and includes the double integrals. With the aid of classical equations of motion, the sum of the contributions of the two-loop diagrams is transformed into the expression which includes one-dimensional integrals only. The specific property of the expression obtained is that the integrand does not possess any singularities in the focal points of the classical trajectory. The general formula takes much simpler form in the case of one-dimensional systems

  13. DOE's Phytoremediation Program

    International Nuclear Information System (INIS)

    Levine, R.S.

    1996-01-01

    This presentation contains an outline of the US DOE's phytoremediation program. A brief overview of the goals, infrastructure, and results of the program is presented. Environmental contaminants addressed include chlorinated hydrocarbons, metals, radionuclides, inorganic wastes, and mixed hazardous and radioactive wastes. Studies of soil remediation using phytoextraction and water remediation using rhizofiltration are briefly described

  14. DOE tries new approaches

    International Nuclear Information System (INIS)

    Kramer, D.; Barber, J.

    1995-01-01

    The US Department of Energy has finally unveiled details of its plan to have a private sector vendor treat and process liquid nuclear wastes at the Hanford weapons site in Washington state. While the document is not the official request for proposals that potential bidders had hoped for, DOE says it is planning a two-phase program under which one or more companies would build and operate a privately financed pretreatment and vitrification facility. In the first phase, a proof-of-concept to begin this year and end in 2002, one or two vendors would be selected to vitrify about 2 million gal of the wastes. DOE says the first-phase waste would be representative of 80% of the total wastes in Hanford's 177 underground tanks. In the second phase, to run through 2028, DOE would choose a vendor to scale up its operations to treat the rest of the 57 million gal at Hanford. a DOE official says facilities that have been built for the initial phase could be used in the subsequent stage, although it is not clear yet technically whether pretreatment and vitrification plants could be built in a modular fashion

  15. Selected DOE headquarters publications

    International Nuclear Information System (INIS)

    1979-04-01

    This publication provides listings of (mainly policy and programmatic) publications which have been issued by headquarters organizations of the Department of Energy; assigned a DOE/XXX- type report number code, where XXX is the 1- to 4-letter code for the issuing headquarters organization; received by the Energy Library; and made available to the public

  16. Robust Stabilization of Fractional-Order Systems with Interval Uncertainties via Fractional-Order Controllers

    Directory of Open Access Journals (Sweden)

    Sayyad Delshad Saleh

    2010-01-01

    Full Text Available Abstract We propose a fractional-order controller to stabilize unstable fractional-order open-loop systems with interval uncertainty whereas one does not need to change the poles of the closed-loop system in the proposed method. For this, we will use the robust stability theory of Fractional-Order Linear Time Invariant (FO-LTI systems. To determine the control parameters, one needs only a little knowledge about the plant and therefore, the proposed controller is a suitable choice in the control of interval nonlinear systems and especially in fractional-order chaotic systems. Finally numerical simulations are presented to show the effectiveness of the proposed controller.

  17. Feedback regulation between autophagy and PKA.

    Science.gov (United States)

    Torres-Quiroz, Francisco; Filteau, Marie; Landry, Christian R

    2015-01-01

    Protein kinase A (PKA) controls diverse cellular processes and homeostasis in eukaryotic cells. Many processes and substrates of PKA have been described and among them are direct regulators of autophagy. The mechanisms of PKA regulation and how they relate to autophagy remain to be fully understood. We constructed a reporter of PKA activity in yeast to identify genes affecting PKA regulation. The assay systematically measures relative protein-protein interactions between the regulatory and catalytic subunits of the PKA complex in a systematic set of genetic backgrounds. The candidate PKA regulators we identified span multiple processes and molecular functions (autophagy, methionine biosynthesis, TORC signaling, protein acetylation, and DNA repair), which themselves include processes regulated by PKA. These observations suggest the presence of many feedback loops acting through this key regulator. Many of the candidate regulators include genes involved in autophagy, suggesting that not only does PKA regulate autophagy but that autophagy also sends signals back to PKA.

  18. NORM regulations

    Energy Technology Data Exchange (ETDEWEB)

    Gray, P. [ed.

    1997-02-01

    The author reviews the question of regulation for naturally occuring radioactive material (NORM), and the factors that have made this a more prominent concern today. Past practices have been very relaxed, and have often involved very poor records, the involvment of contractors, and the disposition of contaminated equipment back into commercial service. The rationale behind the establishment of regulations is to provide worker protection, to exempt low risk materials, to aid in scrap recycling, to provide direction for remediation and to examine disposal options. The author reviews existing regulations at federal and state levels, impending legislation, and touches on the issue of site remediation and potential liabilities affecting the release of sites contaminated by NORM.

  19. 41 CFR 101-26.501-4 - Submission of orders.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Submission of orders. 101-26.501-4 Section 101-26.501-4 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 26-PROCUREMENT SOURCES AND...

  20. 41 CFR 109-26.501-4 - Submission of orders.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Submission of orders. 109-26.501-4 Section 109-26.501-4 Public Contracts and Property Management Federal Property Management Regulations System (Continued) DEPARTMENT OF ENERGY PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 26...

  1. 41 CFR 101-26.310 - Ordering errors.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Ordering errors. 101-26.310 Section 101-26.310 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 26-PROCUREMENT SOURCES AND...

  2. 29 CFR 500.232 - Consent findings and order.

    Science.gov (United States)

    2010-07-01

    ... Administrative Law Judge; and (4) A waiver of any right to challenge or contest the validity of the findings and... 29 Labor 3 2010-07-01 2010-07-01 false Consent findings and order. 500.232 Section 500.232 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS MIGRANT AND...

  3. 48 CFR 217.7103-3 - Solicitations for job orders.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Solicitations for job... REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Master Agreement for Repair and Alteration of Vessels 217.7103-3 Solicitations for job orders. (a) When a...

  4. DOE Patents Available for Licensing

    International Nuclear Information System (INIS)

    Stuber, C.

    1981-01-01

    DOE Patents Available for Licensing (DOE PAL) provides abstracting and indexing coverage of the DOE patent literature, including patent applications, that concerns any apsect of energy production, conservation, and utilization. The citations are arranged by subject category. DOE is prepared to grant exclusive or nonexclusive, revocable licenses under DOE-owned US patents and patent applications in accordance with the provisions of 10CFR781

  5. Court orders on procreation.

    Science.gov (United States)

    Matevosyan, Naira R

    2016-01-01

    The aim of this study is to empirically evaluate judgments entered from 1913 to 2013 in the matters of compulsory sterilization. Holdings and dispositions at the U.S. Appellate and Supreme courts are randomly located in LexisNexis using Shepard's symbols. Continuous variables are processed with the Mantel-Haenszel method. Court orders are used as units of analysis. The majority of cases (56.4 %) concern minors at a mean age of 11.7 years. Forty-four (80 %) petitions are filed by the parents or guardians; 11 (20 %) are parens patriae. Petitions for female sterilization are denied in 56.4 % cases under the Federal Laws (2 U.S.C. 431; 28 U.S.C; 29 U.S.C; 42 U.S.C; 424 U.S.), Procedural due process clause of the 14th Amendment, statutes, and common law precedents. Petitions for female sterilization are granted in 36.4 % cases under the statutory penal codes, the Law of the land, precedents, and the dicta. No significant associations are found between the parity and degree of mental impairment (r = 0.342). Substantial correlations are met between the gender, degree of impairment (r (2) = 0.724), and dispositions (r (2) = 802). The mean age of women is 20.78 years; the mean age of men is 30.25 years. Correlations fail to establish reasoning between the age of the subjects and the entered judgments (r (2) = 0. 356). (1) The female/male ratio (8:1) and age gap of the respondents indicate on a disproportionate impact of the statutes. (2) The procedure of sterilization in itself is incommensurate with equality, as the volume of surgery is uneven in males and females. (3) The case law is instructive with respect to which arguments have not been advanced. (4) Lastly, due to the etiological intricacy of mental impairment, with genetic transmission strikingly different in men and women, expert-witnesses ought to act in a medical vacuum because there is no mathematical certainty as to the transmission mode of the traits in question (exon and intron mutations, triplet repeat

  6. Working with Indian Tribal Nations. A guide for DOE employees

    Energy Technology Data Exchange (ETDEWEB)

    None

    2000-12-31

    U.S. Department of Energy (DOE) employees and contractors frequently work with Indian tribes or nations as part of their jobs. The purpose of this guide is to help DOE employees and contractors initiate contact with tribes and build effective relationships. DOE maintains a unique government-to government relationship with tribal nations. This guide presents an overview of the history of the relationship between the tribes and the Federal government, as well as the laws and Executive Orders that define that relationship. The guide discusses the Federal government’s trust responsibility to the tribes, tribal treaty rights, and the Department of Energy’s American Indian policy. The guide also discusses important cultural differences that could lead to communication problems if not understood and provides examples of potential cultural misunderstandings. In particular the guide discusses tribal environmental beliefs that shape tribal responses to DOE actions. The guide also provides pointers on tribal etiquette during meetings and cultural ceremonies and when visiting tribal reservations. Appendix 1 gives examples of the tribal nations with whom DOE currently has Memoranda of Understanding. While this guide provides an introduction and overview of tribal relations for DOE staff and contractors, DOE has also designated Tribal Issues Points of Contacts at each of its facilities. A list of these Points of Contact for all DOE facilities is provided in Appendix 2. DOE staff and contractors should consult with the appropriate tribal representatives at their site before initiating contact with a tribal nation, because many tribes have rules and procedures that must be complied with before DOE staff or contractors may go on tribal lands or conduct interviews with tribal members. Appendix 3 is the complete DOE American Indian Policy. Appendices 4-6 are Executive Orders that govern the relationship of all federal agencies with tribal nations. DOE employees and staff are

  7. Aggressive Orders and the Resiliency of a Limit Order Market

    NARCIS (Netherlands)

    Degryse, H.A.; de Jong, F.C.J.M.; van Ravenswaaij, M.; Wuyts, G.

    2002-01-01

    We analyze the resiliency of a pure limit order market for large and small capitalization stocks as well as stocks with different tick sizes.We explore the issue of resiliency by investigating the order flow around aggressive orders that move prices.The impact of aggressive orders is gauged in three

  8. A high performance totally ordered multicast protocol

    Science.gov (United States)

    Montgomery, Todd; Whetten, Brian; Kaplan, Simon

    1995-01-01

    This paper presents the Reliable Multicast Protocol (RMP). RMP provides a totally ordered, reliable, atomic multicast service on top of an unreliable multicast datagram service such as IP Multicasting. RMP is fully and symmetrically distributed so that no site bears un undue portion of the communication load. RMP provides a wide range of guarantees, from unreliable delivery to totally ordered delivery, to K-resilient, majority resilient, and totally resilient atomic delivery. These QoS guarantees are selectable on a per packet basis. RMP provides many communication options, including virtual synchrony, a publisher/subscriber model of message delivery, an implicit naming service, mutually exclusive handlers for messages, and mutually exclusive locks. It has commonly been held that a large performance penalty must be paid in order to implement total ordering -- RMP discounts this. On SparcStation 10's on a 1250 KB/sec Ethernet, RMP provides totally ordered packet delivery to one destination at 842 KB/sec throughput and with 3.1 ms packet latency. The performance stays roughly constant independent of the number of destinations. For two or more destinations on a LAN, RMP provides higher throughput than any protocol that does not use multicast or broadcast.

  9. Character order processing in Chinese reading.

    Science.gov (United States)

    Gu, Junjuan; Li, Xingshan; Liversedge, Simon P

    2015-02-01

    We explored how character order information is encoded in isolated word processing or Chinese sentence reading in 2 experiments using a masked priming paradigm and a gaze-contingent display-change paradigm. The results showed that response latencies in the lexical decision task and reading times on the target word region were longer in the unrelated condition (the prime or the preview was unrelated with the target word) than the transposed-character condition (the prime or the preview was a transposition of the 2 characters of the target word), which were respectively longer than in the identity condition (the prime or preview was identical to the target word). These results show that character order is encoded at an early stage of processing in Chinese reading, but character position encoding was not strict. We also found that character order encoding was similar for single-morpheme and multiple-morpheme words, suggesting that morphemic status does not affect character order encoding. The current results represent an early contribution to our understanding of character order encoding during Chinese reading.

  10. Boundary-bulk relation in topological orders

    Directory of Open Access Journals (Sweden)

    Liang Kong

    2017-09-01

    Full Text Available In this paper, we study the relation between an anomaly-free n+1D topological order, which are often called n+1D topological order in physics literature, and its nD gapped boundary phases. We argue that the n+1D bulk anomaly-free topological order for a given nD gapped boundary phase is unique. This uniqueness defines the notion of the “bulk” for a given gapped boundary phase. In this paper, we show that the n+1D “bulk” phase is given by the “center” of the nD boundary phase. In other words, the geometric notion of the “bulk” corresponds precisely to the algebraic notion of the “center”. We achieve this by first introducing the notion of a morphism between two (potentially anomalous topological orders of the same dimension, then proving that the notion of the “bulk” satisfies the same universal property as that of the “center” of an algebra in mathematics, i.e. “bulk = center”. The entire argument does not require us to know the precise mathematical description of a (potentially anomalous topological order. This result leads to concrete physical predictions.

  11. Synthesis of the panel information principles for nuclear regulators: the journalist's view

    International Nuclear Information System (INIS)

    Lippman, T.W.

    1994-01-01

    The four journalists who participated in the OECD Nuclear Energy Agency seminar were M. Thomas Lippman, United States; Ms. Anna Schytt, Sweden; M. Michel Lemeret, Belgium; and M. Francis Sorin, France. Although the nuclear industry is structured differently in each of these countries, the journalists who have written about it for many years agreed on certain basic points. In order to have the confidence of the public, nuclear regulators must function openly, provide accurate and dispassionate information, have a reservoir of available technical knowledge and be independent of government and politics. Their purpose should be to regulate, rather than to promote the nuclear energy industry. The participants agreed that it is part of the regulators' role to provide information to the public on a regular basis, to forestall misunderstanding and potential panic. But this must be done in a way that does not appear to be promoting the nuclear power industry as such. (author)

  12. ASPECTS CONCERNING THE JOINT VENTURE UNDER THE REGULATION OF THE NEW CIVIL CODE

    Directory of Open Access Journals (Sweden)

    Ana-Maria Lupulescu

    2013-11-01

    Full Text Available The New Civil Code makes the transition, for the first time in the Romanian legal system, from the duality to the unity of private law. Consequently, the Civil Code contains a legal regulation more structured and comprehensive, although not entirely safe from any criticism, in relation to the company, with particular reference to the simple company, regulation that expressly characterizes itself as the common law in this field. Within these general provisions, the legislator has considered the joint venture, to which, however, as in the previous regulation contained in the old Commercial Code – now repealed –, it does not devote too many legal provisions, in order to maintain the flexibility of this form of company. Therefore, this approach appears particularly useful for analysts in law and, especially, for practitioners, since it aims to achieve a comprehensive analysis of the joint venture, form of company with practical incidence.

  13. Social cost-efficient service quality-Integrating customer valuation in incentive regulation: Evidence from the case of Norway

    International Nuclear Information System (INIS)

    Growitsch, Christian; Jamasb, Tooraj; Mueller, Christine; Wissner, Matthias

    2010-01-01

    In order to overcome the perverse incentives of excessive maintenance reductions and insufficient network investments arising with incentive regulation of electricity distribution companies, regulators throughout Europe have started regulating service quality. In this paper, we explore the impact of incorporating customers' willingness-to-pay for service quality in benchmarking models on cost efficiency of distribution networks. Therefore, we examine the case of Norway, which features this approach to service quality regulation. We use the data envelopment analysis technique to analyse the effectiveness of such regulatory instruments. Moreover, we discuss the extent to which this indirect regulatory instrument motivates a socially desired service quality level. The results indicate that internalising external or social cost of service quality does not seem to have played an important role in improving cost efficiency in Norwegian distribution utilities.

  14. Social cost-efficient service quality. Integrating customer valuation in incentive regulation. Evidence from the case of Norway

    Energy Technology Data Exchange (ETDEWEB)

    Growitsch, Christian; Mueller, Christine; Wissner, Matthias [WIK, Department Energy Markets and Energy Regulation, Rhoendorfer Str. 68, 53604 Bad Honnef (Germany); Jamasb, Tooraj [University of Cambridge, Faculty of Economics (United Kingdom)

    2010-05-15

    In order to overcome the perverse incentives of excessive maintenance reductions and insufficient network investments arising with incentive regulation of electricity distribution companies, regulators throughout Europe have started regulating service quality. In this paper, we explore the impact of incorporating customers' willingness-to-pay for service quality in benchmarking models on cost efficiency of distribution networks. Therefore, we examine the case of Norway, which features this approach to service quality regulation. We use the data envelopment analysis technique to analyse the effectiveness of such regulatory instruments. Moreover, we discuss the extent to which this indirect regulatory instrument motivates a socially desired service quality level. The results indicate that internalising external or social cost of service quality does not seem to have played an important role in improving cost efficiency in Norwegian distribution utilities. (author)

  15. Social cost-efficient service quality-Integrating customer valuation in incentive regulation: Evidence from the case of Norway

    Energy Technology Data Exchange (ETDEWEB)

    Growitsch, Christian, E-mail: c.growitsch@wik.or [WIK, Department Energy Markets and Energy Regulation, Rhoendorfer Str. 68, 53604 Bad Honnef (Germany); Jamasb, Tooraj [University of Cambridge, Faculty of Economics (United Kingdom); Mueller, Christine; Wissner, Matthias [WIK, Department Energy Markets and Energy Regulation, Rhoendorfer Str. 68, 53604 Bad Honnef (Germany)

    2010-05-15

    In order to overcome the perverse incentives of excessive maintenance reductions and insufficient network investments arising with incentive regulation of electricity distribution companies, regulators throughout Europe have started regulating service quality. In this paper, we explore the impact of incorporating customers' willingness-to-pay for service quality in benchmarking models on cost efficiency of distribution networks. Therefore, we examine the case of Norway, which features this approach to service quality regulation. We use the data envelopment analysis technique to analyse the effectiveness of such regulatory instruments. Moreover, we discuss the extent to which this indirect regulatory instrument motivates a socially desired service quality level. The results indicate that internalising external or social cost of service quality does not seem to have played an important role in improving cost efficiency in Norwegian distribution utilities.

  16. [New theory of holistic integrative physiology and medicine. I: New insight of mechanism of control and regulation of breathing].

    Science.gov (United States)

    Sun, Xing-guo

    2015-07-01

    The modern systemic physiology, based on limit-understand functional classification, has significant limitation and one-sidedness. Human being is organic; we should approach the mechanism of control and regulation of breathing integrating all the systems. We use new theory of holistic integrative physiology and medicine to explain the mechanism of control and regulation of breathing. Except the mean level information, the up-down "W" waveform information of arterial blood gas (ABG) is core signal to control and regulate breathing. In order to do so, we must integrate all systems together. New theory will help to explain some unanswered questions in physiology and medicine, for example: fetal does not breathing; how first breath generate; how respiratory rhythm and frequency generate, etc. Breathing is the sign of life. Mechanism of control and regulation of breathing has to integrate respiration, circulation, nerves, metabolism, exercise, sleep and digestion, absorption and elimination and etc altogether.

  17. High order corrections to the renormalon

    International Nuclear Information System (INIS)

    Faleev, S.V.

    1997-01-01

    High order corrections to the renormalon are considered. Each new type of insertion into the renormalon chain of graphs generates a correction to the asymptotics of perturbation theory of the order of ∝1. However, this series of corrections to the asymptotics is not the asymptotic one (i.e. the mth correction does not grow like m.). The summation of these corrections for the UV renormalon may change the asymptotics by a factor N δ . For the traditional IR renormalon the mth correction diverges like (-2) m . However, this divergence has no infrared origin and may be removed by a proper redefinition of the IR renormalon. On the other hand, for IR renormalons in hadronic event shapes one should naturally expect these multiloop contributions to decrease like (-2) -m . Some problems expected upon reaching the best accuracy of perturbative QCD are also discussed. (orig.)

  18. DOE standard: The Department of Energy Laboratory Accreditation Program administration

    International Nuclear Information System (INIS)

    1998-12-01

    This technical standard describes the US Department of Energy Laboratory Accreditation Program (DOELAP), organizational responsibilities, and the accreditation process. DOELAP evaluates and accredits personnel dosimetry and radiobioassay programs used for worker monitoring and protection at DOE and DOE contractor sites and facilities as required in Title 10, Code of Federal Regulations, Part 835, Occupational Radiation Protection. The purpose of this technical standard is to establish procedures for administering DOELAP and acquiring accreditation

  19. French regulations

    International Nuclear Information System (INIS)

    Ballereau, P.

    1998-01-01

    In this issue are given the new French regulations relative to radiation protection of temporary personnel, the licensing to release gaseous and liquid wastes and the licensing granted to thirty two laboratories using beta and gamma decay radioisotopes. (N.C.)

  20. 76 FR 28193 - Amendments to Material Control and Accounting Regulations

    Science.gov (United States)

    2011-05-16

    ...] Amendments to Material Control and Accounting Regulations AGENCY: Nuclear Regulatory Commission. ACTION... amendments to the material control and accounting (MC&A) regulations. These regulations apply to NRC... ``accounting,'' and thus does not fully describe the accounting aspects that MC&A programs must include...

  1. 1979 DOE statistical symposium

    Energy Technology Data Exchange (ETDEWEB)

    Gardiner, D.A.; Truett T. (comps. and eds.)

    1980-09-01

    The 1979 DOE Statistical Symposium was the fifth in the series of annual symposia designed to bring together statisticians and other interested parties who are actively engaged in helping to solve the nation's energy problems. The program included presentations of technical papers centered around exploration and disposal of nuclear fuel, general energy-related topics, and health-related issues, and workshops on model evaluation, risk analysis, analysis of large data sets, and resource estimation.

  2. 1979 DOE statistical symposium

    International Nuclear Information System (INIS)

    Gardiner, D.A.; Truett, T.

    1980-09-01

    The 1979 DOE Statistical Symposium was the fifth in the series of annual symposia designed to bring together statisticians and other interested parties who are actively engaged in helping to solve the nation's energy problems. The program included presentations of technical papers centered around exploration and disposal of nuclear fuel, general energy-related topics, and health-related issues, and workshops on model evaluation, risk analysis, analysis of large data sets, and resource estimation

  3. DOE headquarters publications

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-09-01

    This bibliography provides listings of (mainly policy and programmatic) publications issued from the U.S. Department of Energy, Washington, D.C. The listings are arranged by the ''report code'' assigned to each of the major organizations at DOE Headquarters, followed by the three categories of environmental reports issued from DOE Headquarters. All of the publications listed, except for those shown as still ''in preparation,'' may be seen in the Energy Library. A title index arranged by title keywords follows the listings. Certain publications are omitted. They include such items as pamphlets, ''fact sheets,'' bulletins and weekly/monthly issuances of DOE's Energy Information Administration and Economic Regulatory Administration, and employee bulletins and newsletters. Omitted from the bibliography altogether are headquarters publications assigned other types of report codes--e.g., ''HCP'' (Headquarters Contractor Publication) and ''CONF'' (conference proceedings). (RWR)

  4. Current DOE direction in low-level waste management

    International Nuclear Information System (INIS)

    Wilhite, E.L.; Dolenc, M.R.; Shupe, M.W.; Waldo, L.C.

    1989-01-01

    The U.S. Department of Energy (DOE) is implementing revised DOE Order 5820.2A Radioactive Waste Management. Chapter III of the revised order provides prescriptive requirements for managing low-level waste and is the subject of this paper. The revised order requires that all DOE low-level radioactive and mixed waste be systematically managed, using an approach that considers the combination of waste management practices used in waste generation reduction, segregation, treatment, packaging, storage, and disposal. The Order defines performance objectives for protecting groundwater, for protecting against intrusion, and for maintaining adequate operational practices. A performance assessment will be required to ensure that waste management operations comply with these performance objectives. DOE implementation of the revised Order includes work in the areas of leach testing, waste stabilization, waste certification, facility monitoring, and management of unique waste streams. This paper summarizes the status of this work and the current direction DOE is taking in managing low-level waste under DOE 5820.2A

  5. Why Does Well

    Science.gov (United States)

    Sartorius, Tara Cady

    2010-01-01

    There is something disappointing about life. It is messy and out of control. It seems the more one tries to put life in order, the more ordering there is to do. The more one seeks explanations, the more confusing things become. Life's an impossible task. Maybe one should just give up. Or, then again, one might as well keep trying. It's this…

  6. Does "g" Exist?

    Science.gov (United States)

    Detterman, Douglas K.

    1982-01-01

    In an argument for orthogonal variables to explain intelligence, higher-order constructs, including "g" as a single thing in intelligence, are suggested to inevitably result from complex systems with interrelated parts. Biological reductionism and other arguments for the higher-order constructs as explanations of intellectual functioning…

  7. Achieving RCRA compliance in DOE defense waste management operations

    International Nuclear Information System (INIS)

    Frankhauser, W.A.; Shepard, M.D.

    1989-01-01

    The U.S. Department of Energy (DOE) generates significant volumes of radioactive mixed waste (RMW) through its defense-related activities. Defense RMW is co-regulated by DOE and the U.S. Environmental Protection Agency/State agencies in accordance with requirements of the Resource Conservation and Recovery Act (RCRA) and the Atomic Energy Act (AEA). This paper highlights some of the problems encountered in co-regulation and discusses achievements of the defense waste management program in integrating RCRA requirements into RMW operations. Defense waste sites are planning facility modifications and major new construction projects to develop treatment, storage and disposal capacity for existing RMW inventories and projected needs

  8. DOE enforcement program roles and responsibilities: DOE handbook

    International Nuclear Information System (INIS)

    1995-08-01

    The Price-Anderson Act provides indemnification to DOE contractors who manage and conduct nuclear activities in the DOE complex. The government acts as an insurer for these contractors against any findings of liability from the nuclear activities of the contractor within the scope of its contract. 10 CFR Part 820 establishes the legal framework for implementing DOE's Nuclear Safety Enforcement Program. Integration with other DOE organizations and programs would assure that the enforcement process properly considers the actual or potential safety significance of a violation when determining an appropriate enforcement sanction. Achieving a proactive contractor compliance assurance rather than a heavy enforcement hand, will require a foundation of cooperation and teamwork across DOE organizations. This handbook identifies the areas of interface for the DOE Enforcement Program and provides guidance on roles and responsibilities for the key DOE organizational areas. It complements DOE-HDBK-1087-95 and 1089-95

  9. Building strong brands – does it matter?

    OpenAIRE

    Aure, Kristin Gaaseide; Nervik, Kristine Dybvik

    2014-01-01

    Brand equity has proven, through several decades of research, to be a primary source of competitive advantage and future earnings (Yoo & Donthu, 2001). Building strong brands has therefore become a priority for many organizations, with the presumption that building strong brands yields these advantages (Yasin et al., 2007). A quantitative survey was conducted at Sunnmøre in Norway in order to answer the two developed research questions. - Does the brand equity dimensions; brand...

  10. Impact of occupational issues on DOE's environmental restoration program

    International Nuclear Information System (INIS)

    Siegel, M.R.; Lesperance, A.M.; Smith, D.

    1992-01-01

    The U.S. Department of Energy (DOE) is in the midst of a 30-yr, multi-billion-dollar environmental restoration program for most of the facilities included in its nuclear weapons complex. Long-term planning efforts are under way to identify strategies and approaches for carrying out this extraordinarily complicated task. The DOE has already entered into interagency agreements with the U.S. Environmental Protection Agency and states for many of its environmental restoration sites. These agreements set legally enforceable deadlines for cleanup activities at these sites. In addition, DOE has made other commitments to Congress and the public regarding its environmental restoration schedule. Thousands of workers will be directly involved in environmental restoration activities at DOE sites. Cleanup activity will be carried out in environments involving potential exposure to highly toxic chemical substances and radionuclides. It is inevitable that occupational safety and health (OSH) issues will become both critical and highly visible to DOE. The OSH issues associated with cleanup activities will likely attract the attention of workers, unions, the media, regulators, and the public. This paper reviews three case studies describing OSH activities in DOE's environmental restoration program. These case studies will help alert DOE officials to ways that various OSH issues should be considered when planning environmental restoration activities. This activity is being coordinated with other DOE work to identify occupational requirements that are applicable to DOE cleanup work

  11. Licensed reactor nuclear safety criteria applicable to DOE reactors

    International Nuclear Information System (INIS)

    1993-11-01

    This document is a compilation and source list of nuclear safety criteria that the Nuclear Regulatory Commission (NRC) applies to licensed reactors; it can be used by DOE and DOE contractors to identify NRC criteria to be evaluated for application to the DOE reactors under their cognizance. The criteria listed are those that are applied to the areas of nuclear safety addressed in the safety analysis report of a licensed reactor. They are derived from federal regulations, USNRC regulatory guides, Standard Review Plan (SRP) branch technical positions and appendices, and industry codes and standards

  12. Commercial Decommissioning at DOE's Rocky Flats

    International Nuclear Information System (INIS)

    Freiboth, C.; Sandlin, N.; Schubert, A.; Hansen, S.

    2002-01-01

    Due in large part to the number of nuclear facilities that make up the DOE complex, DOE-EM work has historically been paperwork intensive and driven by extensive regulations. Requirements for non-nuclear facilities are often grouped with those of nuclear facilities, driving up costs. Kaiser-Hill was interested in applying a commercial model to demolition of these facilities and wanted to apply necessary and sufficient standards to the work activities, but avoid applying unnecessary requirements. Faced with demolishing hundreds of uncontaminated or non-radiologically contaminated facilities, Kaiser-Hill has developed a subcontracting strategy to drastically reduce the cost of demolishing these facilities at Rocky Flats. Aiming to tailor the demolition approach of such facilities to more closely follow commercial practices, Kaiser-Hill recently released a Request for Proposals (RFP) for the demolition of the site's former central administration facility. The RFP significantly reduced requirements for compliance with specific DOE directives. Instead, the RFP required subcontractors to comply with health and safety requirements commonly found in the demolition of similar facilities in a commercial setting. This resulted in a number of bids from companies who have normally not bid on DOE work previously and at a reduced cost over previous approaches. This paper will discuss the details of this subcontracting strategy

  13. DOE technical standards list: Directory of DOE and contractor personnel involved in non-government standards activities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-08-01

    The body of this document contains a listing of DOE employees and DOE contractors who have submitted form DOE F 1300.2, Record of Non-Government Standards Activity, which is attached to the end of this document and to DOE Order 1300.2A. Additional names were added from rosters supplied by non-Government standards bodies. The committees or governing bodies in which the person participates is listed after each name. An asterisk preceding the committee notation indicates that the person has identified himself or herself as the DOE representative on that committee. Appendices to this document are also provided to sort the information by the parent employment organization, by non-Government standards activity, and by the proper names of the non-Government standards organizations and committees. DOE employees and contractors listed in this TSL are those recorded as of July 1, 1996.

  14. 29 CFR 1921.8 - Consent findings and order.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Consent findings and order. 1921.8 Section 1921.8 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... WORKERS' COMPENSATION ACT Prehearing Procedures § 1921.8 Consent findings and order. (a) General. At any...

  15. 22 CFR 128.17 - Availability of orders.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Availability of orders. 128.17 Section 128.17 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS ADMINISTRATIVE PROCEDURES..., probationary periods, and interim suspension orders are available for public inspection in the Public Reading...

  16. 8 CFR 1241.20 - Aliens ordered excluded.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Aliens ordered excluded. 1241.20 Section 1241.20 Aliens and Nationality EXECUTIVE OFFICE FOR IMMIGRATION REVIEW, DEPARTMENT OF JUSTICE IMMIGRATION REGULATIONS APPREHENSION AND DETENTION OF ALIENS ORDERED REMOVED Deportation of Excluded Aliens...

  17. 8 CFR 1241.30 - Aliens ordered deported.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Aliens ordered deported. 1241.30 Section 1241.30 Aliens and Nationality EXECUTIVE OFFICE FOR IMMIGRATION REVIEW, DEPARTMENT OF JUSTICE IMMIGRATION REGULATIONS APPREHENSION AND DETENTION OF ALIENS ORDERED REMOVED Deportation of Aliens in the...

  18. 7 CFR 1000.85 - Assessment for order administration.

    Science.gov (United States)

    2010-01-01

    ... Federal milk order each handler shall pay to the market administrator its pro rata share of the expense of administration of the order at a rate specified by the market administrator that is no more than 5 cents per... disposition in the marketing area from a partially regulated distributing plant that exceeds the skim milk and...

  19. Service order execution procedure (in terms of labour law

    Directory of Open Access Journals (Sweden)

    Ana VIDAT

    2015-06-01

    Full Text Available From the perspective of labor law, it is understood that the execution of the order of service, the essence of labor discipline, has in principle lawful purpose and, consequently, can not attract liability. It requires, however, the regulation mechanism by which theoretical assertions regarding order execution service materializes from a procedural standpoint.

  20. Radiation exposures for DOE and DOE contractor employees, 1987

    International Nuclear Information System (INIS)

    1989-10-01

    This report is one of series of annual reports provided by the US Department of Energy (DOE) summarizing occupational radiation exposures received by DOE and DOE contractor employees. These reports provide an overview of radiation exposures received each year, as well as identification of trends in exposures being experienced over the years. 5 figs., 30 tabs