WorldWideScience

Sample records for registration current controlled

  1. Image registration with auto-mapped control volumes

    International Nuclear Information System (INIS)

    Schreibmann, Eduard; Xing Lei

    2006-01-01

    inhale and exhale phases of a lung 4D CT. Algorithm convergence was confirmed by starting the registration calculations from a large number of initial transformation parameters. An accuracy of ∼2 mm was achieved for both deformable and rigid registration. The proposed image registration method greatly reduces the complexity involved in the determination of homologous control points and allows us to minimize the subjectivity and uncertainty associated with the current manual interactive approach. Patient studies have indicated that the two-step registration technique is fast, reliable, and provides a valuable tool to facilitate both rigid and nonrigid image registrations

  2. Drug Establishments Current Registration Site

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Drug Establishments Current Registration Site (DECRS) is a database of current information submitted by drug firms to register establishments (facilities) which...

  3. Signal shape registration in the JINR synchrophasotron slowly extracted beam parameter control system

    International Nuclear Information System (INIS)

    Volkov, V.I.; Kulikov, I.I.; Romanov, S.V.

    1982-01-01

    Signal shape registration in the JINR synchrophasotron slowly estracted beam parameter control system on-line with the ES-1010 computer is described. 32 input signals can be connected to the registrator. The maximum measurement rate of signal shape registration is about 38 kHz. The registrator consists of 32-channel analog multiplexer, 10-bit analog-to-digital converter, 1024-word buffer memory and control circuits. For information representation the colour TV monitor is used

  4. Victoria's review of registration for health practitioners.

    Science.gov (United States)

    Scotts, H; Carter, M

    1988-01-01

    This article discusses some of the issues raised in the Interim Report of the current Review of Registration of Health Practitioners being conducted for the Victorian Health Department. The Report attempts to develop the framework in which the registration Boards will operate as part of a cohesive registration system. It proposed a mechanism and criteria for the registration of new groups as well as principles which can be applied to the ongoing review of each existing Board. The Review takes the perspective that registration of health practitioners carries with it both advantages and disadvantages for the general community. Under the proposed new system the controls exercised over health care providers by Registration Boards would be evaluated on the basis of to what extent the benefits to the public outweighed the potential costs. It is in this context that the Report addresses issues such as consumer complaints handling, registration of individual practitioners and controls over professional advertising and other business practices.

  5. Image registration assessment in radiotherapy image guidance based on control chart monitoring.

    Science.gov (United States)

    Xia, Wenyao; Breen, Stephen L

    2018-04-01

    Image guidance with cone beam computed tomography in radiotherapy can guarantee the precision and accuracy of patient positioning prior to treatment delivery. During the image guidance process, operators need to take great effort to evaluate the image guidance quality before correcting a patient's position. This work proposes an image registration assessment method based on control chart monitoring to reduce the effort taken by the operator. According to the control chart plotted by daily registration scores of each patient, the proposed method can quickly detect both alignment errors and image quality inconsistency. Therefore, the proposed method can provide a clear guideline for the operators to identify unacceptable image quality and unacceptable image registration with minimal effort. Experimental results demonstrate that by using control charts from a clinical database of 10 patients undergoing prostate radiotherapy, the proposed method can quickly identify out-of-control signals and find special cause of out-of-control registration events.

  6. TU-B-19A-01: Image Registration II: TG132-Quality Assurance for Image Registration

    International Nuclear Information System (INIS)

    Brock, K; Mutic, S

    2014-01-01

    AAPM Task Group 132 was charged with a review of the current approaches and solutions for image registration in radiotherapy and to provide recommendations for quality assurance and quality control of these clinical processes. As the results of image registration are always used as the input of another process for planning or delivery, it is important for the user to understand and document the uncertainty associate with the algorithm in general and the Result of a specific registration. The recommendations of this task group, which at the time of abstract submission are currently being reviewed by the AAPM, include the following components. The user should understand the basic image registration techniques and methods of visualizing image fusion. The disclosure of basic components of the image registration by commercial vendors is critical in this respect. The physicists should perform end-to-end tests of imaging, registration, and planning/treatment systems if image registration is performed on a stand-alone system. A comprehensive commissioning process should be performed and documented by the physicist prior to clinical use of the system. As documentation is important to the safe implementation of this process, a request and report system should be integrated into the clinical workflow. Finally, a patient specific QA practice should be established for efficient evaluation of image registration results. The implementation of these recommendations will be described and illustrated during this educational session. Learning Objectives: Highlight the importance of understanding the image registration techniques used in their clinic. Describe the end-to-end tests needed for stand-alone registration systems. Illustrate a comprehensive commissioning program using both phantom data and clinical images. Describe a request and report system to ensure communication and documentation. Demonstrate an clinically-efficient patient QA practice for efficient evaluation of image

  7. Nursing philosophy: A review of current pre registration curricula in the UK.

    Science.gov (United States)

    Mackintosh-Franklin, Carolyn

    2016-02-01

    Nursing in the UK has been subject to criticism for failing to provide care and compassion in practice, with a series of reports highlighting inadequacies in care. This scrutiny provides nursing with an ideal opportunity to evaluate the underpinning philosophy of nursing practice, and for nurse educators to use this philosophy as the basis for programmes which can inculcate neophyte student nurses with a fundamental understanding of the profession, whilst providing other health care professionals and service users with a clear representation of professional nursing practice. The key word philosophy was used in a systematic stepwise descriptive content analysis of the programme specifications of 33 current undergraduate programme documents, leading to an undergraduate award and professional registration as a nurse. The word philosophy featured minimally in programme specification documents, with 12 (36%) documents including it. Its use was superficial in 3 documents and focused on educational philosophy in a further 3 documents. 2 programme specifications identified their philosophy as the NMC (2010) standards for pre-registration nurse education. 2 programme specifications articulated a philosophy specific to that programme and HEI, focusing on caring, and 2 made reference to underpinning philosophies present in nursing literature; the Relationship Centred Care Approach, and The Humanising Care Philosophy. The philosophy of nursing practice is not clearly articulated in pre-registration curricula. This failure to identify the fundamental nature of nursing is detrimental to the development of the profession, and given this lack of direction it is not surprising that some commentators feel nursing has lost its way. Nurse educators must review their current curricula to ensure that there is clear articulation of nursing's professional philosophical stance, and use this as the framework for pre-registration curricula to support the development of neophyte nursing

  8. A fast alignment method for breast MRI follow-up studies using automated breast segmentation and current-prior registration

    Science.gov (United States)

    Wang, Lei; Strehlow, Jan; Rühaak, Jan; Weiler, Florian; Diez, Yago; Gubern-Merida, Albert; Diekmann, Susanne; Laue, Hendrik; Hahn, Horst K.

    2015-03-01

    In breast cancer screening for high-risk women, follow-up magnetic resonance images (MRI) are acquired with a time interval ranging from several months up to a few years. Prior MRI studies may provide additional clinical value when examining the current one and thus have the potential to increase sensitivity and specificity of screening. To build a spatial correlation between suspicious findings in both current and prior studies, a reliable alignment method between follow-up studies is desirable. However, long time interval, different scanners and imaging protocols, and varying breast compression can result in a large deformation, which challenges the registration process. In this work, we present a fast and robust spatial alignment framework, which combines automated breast segmentation and current-prior registration techniques in a multi-level fashion. First, fully automatic breast segmentation is applied to extract the breast masks that are used to obtain an initial affine transform. Then, a non-rigid registration algorithm using normalized gradient fields as similarity measure together with curvature regularization is applied. A total of 29 subjects and 58 breast MR images were collected for performance assessment. To evaluate the global registration accuracy, the volume overlap and boundary surface distance metrics are calculated, resulting in an average Dice Similarity Coefficient (DSC) of 0.96 and root mean square distance (RMSD) of 1.64 mm. In addition, to measure local registration accuracy, for each subject a radiologist annotated 10 pairs of markers in the current and prior studies representing corresponding anatomical locations. The average distance error of marker pairs dropped from 67.37 mm to 10.86 mm after applying registration.

  9. System composition and operation of exposure dose registration and control system (Final report)

    International Nuclear Information System (INIS)

    1978-01-01

    Since November, 1976, the committee concerning the investigation of exposure dose registration and control system for employees in nuclear industries has discussed on the exposure dose registration and control system, issued the interim report (outline) in April, 1977, and continued to investigate the details organizing the working group. Here, the final report is presented. It describes first on the definition of the terms used and the basic concept of the exposure dose registration and control system, in which the name of that organization is decided as ''Central Registration Office for Radiation Works'', Radiation Influence Association, the foundational juridical person. Next, the works to be performed in the Center and nuclear energy enterprises are explained. The items concerning the business management at the time of practical execution are the major part of the report, and are over 22 items. These include the registration business, the official reporting business, inquiry and answer business about career, change and revision, and computer processing system. As the temporary measures for transfer ring to the new system, 10 items are also provided. Supplementary explanation of 9 important items is given in the appendix. (Wakatsuki, Y.)

  10. Control over structure-specific flexibility improves anatomical accuracy for point-based deformable registration in bladder cancer radiotherapy.

    Science.gov (United States)

    Wognum, S; Bondar, L; Zolnay, A G; Chai, X; Hulshof, M C C M; Hoogeman, M S; Bel, A

    2013-02-01

    Future developments in image guided adaptive radiotherapy (IGART) for bladder cancer require accurate deformable image registration techniques for the precise assessment of tumor and bladder motion and deformation that occur as a result of large bladder volume changes during the course of radiotherapy treatment. The aim was to employ an extended version of a point-based deformable registration algorithm that allows control over tissue-specific flexibility in combination with the authors' unique patient dataset, in order to overcome two major challenges of bladder cancer registration, i.e., the difficulty in accounting for the difference in flexibility between the bladder wall and tumor and the lack of visible anatomical landmarks for validation. The registration algorithm used in the current study is an extension of the symmetric-thin plate splines-robust point matching (S-TPS-RPM) algorithm, a symmetric feature-based registration method. The S-TPS-RPM algorithm has been previously extended to allow control over the degree of flexibility of different structures via a weight parameter. The extended weighted S-TPS-RPM algorithm was tested and validated on CT data (planning- and four to five repeat-CTs) of five urinary bladder cancer patients who received lipiodol injections before radiotherapy. The performance of the weighted S-TPS-RPM method, applied to bladder and tumor structures simultaneously, was compared with a previous version of the S-TPS-RPM algorithm applied to bladder wall structure alone and with a simultaneous nonweighted S-TPS-RPM registration of the bladder and tumor structures. Performance was assessed in terms of anatomical and geometric accuracy. The anatomical accuracy was calculated as the residual distance error (RDE) of the lipiodol markers and the geometric accuracy was determined by the surface distance, surface coverage, and inverse consistency errors. Optimal parameter values for the flexibility and bladder weight parameters were determined

  11. Control over structure-specific flexibility improves anatomical accuracy for point-based deformable registration in bladder cancer radiotherapy

    International Nuclear Information System (INIS)

    Wognum, S.; Chai, X.; Hulshof, M. C. C. M.; Bel, A.; Bondar, L.; Zolnay, A. G.; Hoogeman, M. S.

    2013-01-01

    Purpose: Future developments in image guided adaptive radiotherapy (IGART) for bladder cancer require accurate deformable image registration techniques for the precise assessment of tumor and bladder motion and deformation that occur as a result of large bladder volume changes during the course of radiotherapy treatment. The aim was to employ an extended version of a point-based deformable registration algorithm that allows control over tissue-specific flexibility in combination with the authors’ unique patient dataset, in order to overcome two major challenges of bladder cancer registration, i.e., the difficulty in accounting for the difference in flexibility between the bladder wall and tumor and the lack of visible anatomical landmarks for validation. Methods: The registration algorithm used in the current study is an extension of the symmetric-thin plate splines-robust point matching (S-TPS-RPM) algorithm, a symmetric feature-based registration method. The S-TPS-RPM algorithm has been previously extended to allow control over the degree of flexibility of different structures via a weight parameter. The extended weighted S-TPS-RPM algorithm was tested and validated on CT data (planning- and four to five repeat-CTs) of five urinary bladder cancer patients who received lipiodol injections before radiotherapy. The performance of the weighted S-TPS-RPM method, applied to bladder and tumor structures simultaneously, was compared with a previous version of the S-TPS-RPM algorithm applied to bladder wall structure alone and with a simultaneous nonweighted S-TPS-RPM registration of the bladder and tumor structures. Performance was assessed in terms of anatomical and geometric accuracy. The anatomical accuracy was calculated as the residual distance error (RDE) of the lipiodol markers and the geometric accuracy was determined by the surface distance, surface coverage, and inverse consistency errors. Optimal parameter values for the flexibility and bladder weight

  12. Control over structure-specific flexibility improves anatomical accuracy for point-based deformable registration in bladder cancer radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Wognum, S.; Chai, X.; Hulshof, M. C. C. M.; Bel, A. [Department of Radiotherapy, Academic Medical Center, Meiberdreef 9, 1105 AZ Amsterdam (Netherlands); Bondar, L.; Zolnay, A. G.; Hoogeman, M. S. [Department of Radiation Oncology, Daniel den Hoed Cancer Center, Erasmus Medical Center, Groene Hilledijk 301, 3075 EA Rotterdam (Netherlands)

    2013-02-15

    Purpose: Future developments in image guided adaptive radiotherapy (IGART) for bladder cancer require accurate deformable image registration techniques for the precise assessment of tumor and bladder motion and deformation that occur as a result of large bladder volume changes during the course of radiotherapy treatment. The aim was to employ an extended version of a point-based deformable registration algorithm that allows control over tissue-specific flexibility in combination with the authors' unique patient dataset, in order to overcome two major challenges of bladder cancer registration, i.e., the difficulty in accounting for the difference in flexibility between the bladder wall and tumor and the lack of visible anatomical landmarks for validation. Methods: The registration algorithm used in the current study is an extension of the symmetric-thin plate splines-robust point matching (S-TPS-RPM) algorithm, a symmetric feature-based registration method. The S-TPS-RPM algorithm has been previously extended to allow control over the degree of flexibility of different structures via a weight parameter. The extended weighted S-TPS-RPM algorithm was tested and validated on CT data (planning- and four to five repeat-CTs) of five urinary bladder cancer patients who received lipiodol injections before radiotherapy. The performance of the weighted S-TPS-RPM method, applied to bladder and tumor structures simultaneously, was compared with a previous version of the S-TPS-RPM algorithm applied to bladder wall structure alone and with a simultaneous nonweighted S-TPS-RPM registration of the bladder and tumor structures. Performance was assessed in terms of anatomical and geometric accuracy. The anatomical accuracy was calculated as the residual distance error (RDE) of the lipiodol markers and the geometric accuracy was determined by the surface distance, surface coverage, and inverse consistency errors. Optimal parameter values for the flexibility and bladder weight

  13. 77 FR 5848 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2012-02-06

    ... October 7, 2011, 76 FR 62449, Johnson Matthey Inc., Custom Pharmaceuticals Department, 2003 Nolte Drive... substance listed in schedule II. The company plans to manufacture the listed controlled substance for sale... registration of Johnson Matthey Inc. to manufacture the listed basic class of controlled substance is...

  14. 78 FR 30331 - Importer of Controlled Substances; Notice of Registration; Meridian Medical Technologies

    Science.gov (United States)

    2013-05-22

    ... Registration; Meridian Medical Technologies By Notice dated March 7, 2012, and published in the Federal Register on March 13, 2013, 78 FR 15974, Meridian Medical Technologies, 2555 Hermelin Drive, St. Louis... that the registration of Meridian Medical Technologies to import the basic class of controlled...

  15. 17 CFR 274.13 - Form N-8B-3, registration statement of unincorporated management investment companies currently...

    Science.gov (United States)

    2010-04-01

    ... statement of unincorporated management investment companies currently issuing periodic payment plan...-8B-3, registration statement of unincorporated management investment companies currently issuing..., pursuant to section 8(b) of the Investment Company Act of 1940, by unincorporated management investment...

  16. 77 FR 31388 - Importer of Controlled Substances; Notice of Registration; Capricorn Pharma, Inc.

    Science.gov (United States)

    2012-05-25

    ... Registration; Capricorn Pharma, Inc. By Notice dated March 8, 2012, and published in the Federal Register on March 20, 2012, 77 FR 16262, Capricorn Pharma, Inc., 6900 English Muffin Way, Unit A, Frederick... registration of Capricorn Pharma, Inc., to import the basic class of controlled substance is consistent with...

  17. 78 FR 64020 - Manufacturer of Controlled Substances; Notice of Registration; Siegfried USA, LLC

    Science.gov (United States)

    2013-10-25

    ...; Notice of Registration; Siegfried USA, LLC By Notice dated May 22, 2013, and published in the Federal Register on May 30, 2013, 78 FR 32458, Siegfried USA, LLC., 33 Industrial Park Road, Pennsville, New Jersey... determined that the registration of Siegfried USA, LLC., to manufacture the listed basic class of controlled...

  18. 75 FR 69462 - Importer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2010-11-12

    ... 36683), Boehringer Ingelheim Chemicals, Inc., 2820 N. Normandy Drive, Petersburg, Virginia 23805, made... registration of Boehringer Ingelheim Chemicals, Inc. to import the basic class of controlled substance is..., conventions, or protocols in effect on [[Page 69463

  19. EL CONTROL DE LA ACTIVIDAD REGISTRAL COOPERATIVA: ESTUDIO CRÍTICO SOBRE SUS DIFICULTADES E INCÓGNITAS/THE CONTROL OF THE REGISTRAL ACTIVITY ON CO-OPERATIVES: A CRITICAL STUDY OF ITS DIFFICULTIES AND ENIGMAS

    Directory of Open Access Journals (Sweden)

    María BURZACO SAMPER

    2009-09-01

    Full Text Available La configuración de los Registros de Cooperativas como instrumentos de carácter administrativo con eficacia jurídica encierra una serie de dificultades de indudable trascendencia práctica entre los que destaca el control de la actividad registral. En este sentido, la multiplicidad normativa característica del actual escenario jurídico cooperativo propicia la existencia de soluciones divergentes que, al margen de los problemas que plantean sobre un eventual exceso competencial, pueden tener incidencia tanto en la seguridad jurídica como en el tipo y alcance de la fiscalización judicial. Por otro lado, la naturaleza híbrida de los Registros de Cooperativas provoca distorsiones cuya salida no siempre es clara, en cuanto las previsiones legales y reglamentarias chocan con ciertas limitaciones de la normativa administrativa general aplicable: así ocurre singularmente con el principio registral de legitimación en relación con aquellos mecanismos de control en vía administrativa cuya puesta en marcha corresponde de oficio a la propia Administración Pública./The configuration of the Registries of Cooperatives as administrative instruments withlegal effect, raises a series of difficulties of doubtless practical importance. Out of them, wecan underline one: the control behind the registration activity.In this sense, the multiplying number of norms that shape current legal cooperativescene, may involve many divergent resolutions that, on top of the issues caused behind apotential excess of competence, may also has consequences on both the legal security as wellas on the nature and reach of the judicial control.On the other hand, the hybrid character of the Registries of Cooperatives may needsome adjustments whose solution is not always clear, due to the legal and legitimateassessments mismatching some restrictions of the applicable general administrative norm.This can be illustrated behind the registry principle of legitimacy, related to

  20. 77 FR 75670 - Importer of Controlled Substances; Notice of Registration; Fisher Clinical Services,Inc.

    Science.gov (United States)

    2012-12-21

    ... Registration; Fisher Clinical Services,Inc. By Notice dated September 20, 2012, and published in the Federal Register on October 2, 2012, 77 FR 60143, Fisher Clinical Services, Inc., 7554 Schantz Road, Allentown... that the registration of Fisher Clinical Services, Inc., to import the basic class of controlled...

  1. 78 FR 23958 - Importer of Controlled Substances: Notice of Registration; Fisher Clinical Services, Inc.

    Science.gov (United States)

    2013-04-23

    ... Registration; Fisher Clinical Services, Inc. By Notice dated November 27, 2012, and published in the Federal Register on December 5, 2012, 77 FR 72409, Fisher Clinical Services, Inc., 7554 Schantz Road, Allentown... the registration of Fisher Clinical Services, Inc., to import the basic class of controlled substance...

  2. 78 FR 5497 - Importer of Controlled Substances; Notice of Registration; Fisher Clinical Services, Inc.

    Science.gov (United States)

    2013-01-25

    ... Registration; Fisher Clinical Services, Inc. By Notice dated November 1, 2012, and published in the Federal Register on November 9, 2012, 77 FR 67396, Fisher Clinical Services, Inc., 7554 Schantz Road, Allentown... the registration of Fisher Clinical Services, Inc., to import the basic class of controlled substance...

  3. 77 FR 50162 - Importer of Controlled Substances; Notice of Registration; Almac Clinical Services, Inc.

    Science.gov (United States)

    2012-08-20

    ... Register on April 26, 2012, 77 FR 24985, Almac Clinical Services, Inc., (ACSI), 25 Fretz Road, Souderton... that the registration of Almac Clinical Services, Inc. (ACSI) to import the basic classes of controlled..., Inc. (ACSI) to ensure that the company's registration is consistent with the public interest. The...

  4. 76 FR 17969 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2011-03-31

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration By Notice dated November 1, 2010, and published in the Federal Register on November 12, 2010, 75 FR 69464, Cerilliant Corporation, 811 Paloma Drive, Suite A, Round Rock, Texas 78665...

  5. 75 FR 10314 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2010-03-05

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration By Notice dated September 17, 2009, and published in the Federal Register on September 25, 2009, (74 FR 49020), Cerilliant Corporation, 811 Paloma Drive, Suite A, Round Rock, Texas...

  6. 76 FR 10069 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2011-02-23

    ... time. DEA has investigated Johnson Matthey Inc. to ensure that the company's registration is consistent... 26, 2010, 75 FR 65659, Johnson Matthey Inc., Custom Pharmaceuticals Department, 2003 Nolte Drive... Sufentanil (9740) II Fentanyl (9801) II The company plans to manufacture the listed controlled substances in...

  7. 76 FR 7234 - Importer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2011-02-09

    ... 64743, Johnson Matthey, Inc., Pharmaceutical Materials, 2003 Nolte Drive, West Deptford, New Jersey... Concentrate of Poppy Straw (9670) II The company plans to import the listed controlled substances as raw...), and determined that the registration of Johnson Matthey, Inc. to import the basic classes of...

  8. 75 FR 32505 - Importer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2010-06-08

    ... Johnson Matthey, Inc. to ensure that the company's registration is consistent with the public interest... 55858), Johnson Matthey, Inc., Pharmaceutical Materials, 2003 Nolte Drive, West Deptford, New Jersey... Poppy Straw Concentrate (9670) II The company plans to import the listed controlled substances as raw...

  9. 75 FR 9615 - Manufacturer of Controlled Substances Notice of Registration

    Science.gov (United States)

    2010-03-03

    .... DEA has investigated Johnson Matthey Inc. to ensure that the company's registration is consistent with..., 2009, (74 FR 55588), Johnson Matthey Inc., Custom Pharmaceuticals Department, 2003 Nolte Drive, West... Sufentanil (9740) II Fentanyl (9801) II The company plans to manufacture the listed controlled substances in...

  10. 75 FR 10313 - Importer of Controlled Substances Notice of Registration

    Science.gov (United States)

    2010-03-05

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Importer of Controlled Substances Notice of Registration By Notice dated October 21, 2009, and published in the Federal Register on October 28, 2009 (74 FR 55584), Cerilliant Corporation, 811 Paloma Drive, Suite A, Round Rock, Texas 78665-2402, made...

  11. 76 FR 8776 - Importer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2011-02-15

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Importer of Controlled Substances; Notice of Registration By Notice dated November 1, 2010, and published in the Federal Register on November 12, 2010, 75 FR 69459, Cerilliant Corporation, 811 Paloma Drive, Suite A, Round Rock, Texas 78665-2402, made...

  12. 75 FR 10312 - Importer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2010-03-05

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Importer of Controlled Substances; Notice of Registration By Notice dated October 20, 2009, and published in the Federal Register on October 28, 2009 (74 FR 55583), Formulation Technologies LLC., 11501 Domain Drive, Suite 130, Austin, Texas 78758, made...

  13. 76 FR 8775 - Importer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2011-02-15

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Importer of Controlled Substances; Notice of Registration By Notice dated November 1, 2010, and published in the Federal Register on November 12, 2010, 75 FR 69459, Formulation Technologies LLC., 11501 Domain Drive, Suite 130, Austin, Texas 78758, made...

  14. 75 FR 69462 - Importer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2010-11-12

    ... 53718), Cambrex Charles City, Inc., 1205 11th Street, Charles City, Iowa 50616, made application by... bulk intermediate which will be distributed in bulk to the company's customers. No comments or... that the registration of Cambrex Charles City, Inc. to import the basic classes of controlled...

  15. 75 FR 69461 - Importer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2010-11-12

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Importer of Controlled Substances; Notice of Registration By Notice dated June 17, 2010, and published in the Federal Register on June 28, 2010 (75 FR 36684), Cerilliant Corporation, 811 Paloma Drive, Suite A, Round Rock, Texas 78665-2402, made application by letter...

  16. 76 FR 36578 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2011-06-22

    ... firm plans to manufacture the listed controlled substances for internal use and for sale to other companies. No comments or objections have been received. DEA has considered the factors in 21 U.S.C. 823(a..., Inc., to ensure that the company's registration is consistent with the public interest. The...

  17. 75 FR 44287 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2010-07-28

    ... firm plans to manufacture the listed controlled substances for internal use and for sale to other companies. No comments or objections have been received. DEA has considered the factors in 21 U.S.C. 823(a..., Inc., to ensure that the company's registration is consistent with the public interest. The...

  18. 76 FR 17968 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2011-03-31

    ... 1, 2010, (75 FR 53720), Austin Pharma LLC., 811 Paloma Drive, Suite A, Round Rock, Texas 78665-2402...) and determined that the registration of Austin Pharma LLC. to manufacture the listed basic classes of controlled substances is consistent with the public interest at this time. DEA has investigated Austin Pharma...

  19. 77 FR 2324 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2012-01-17

    ..., 2011, 76 FR 51401, Austin Pharma LLC., 811 Paloma Drive, Suite C, Round Rock, Texas 78665-2402, made...) and determined that the registration of Austin Pharma LLC. to manufacture the listed basic classes of controlled substances is consistent with the public interest at this time. DEA has investigated Austin Pharma...

  20. 78 FR 64016 - Importer of Controlled Substances, Notice of Registration, Akorn, Inc.

    Science.gov (United States)

    2013-10-25

    ...), a basic class of controlled substance listed in schedule II. The company plans to import Remifentanil in bulk for use in dosage form manufacturing. No comments or objections have been received. DEA... granted registration as an importer of the basic class of controlled substance listed. Dated: September 27...

  1. 77 FR 5849 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2012-02-06

    ... October 7, 2011, 76 FR 62449, Cambrex Charles City, Inc., 1205 11th Street, Charles City, Iowa 50616, made... Sufentanil (9740) II Fentanyl (9801) II The company will manufacture the listed controlled substances in bulk... factors in 21 U.S.C. 823(a) and determined that the registration of Cambrex Charles City, Inc. to...

  2. Registration of Space Objects

    Science.gov (United States)

    Schmidt-Tedd, Bernhard

    2017-07-01

    Space objects are subject to registration in order to allocate "jurisdiction and control" over those objects in the sovereign-free environment of outer space. This approach is similar to the registration of ships in view of the high sea and for aircrafts with respect to the international airspace. Registration is one of the basic principles of space law, starting with UN General Assembly Resolution 1721 B (XVI) of December 20, 1961, followed by Resolution 1962 (XVIII) of December 13, 1963, then formulated in Article VIII of the Outer Space Treaty of 1967 and as specified in the Registration Convention of 1975. Registration of space objects can be seen today as a principle of customary international law, relevant for each spacefaring state. Registration is divided into a national and an international level. The State Party establishes a national registry for its space objects, and those registrations have to be communicated via diplomatic channel to the UN Register of space objects. This UN Register is handled by the UN Office for Outer Space Affairs (UNOOSA) and is an open source of information for space objects worldwide. Registration is linked to the so-called launching state of the relevant space object. There might be more than one launching state for the specific launch event, but only one state actor can register a specific space object. The state of registry gains "jurisdiction and control" over the space object and therefore no double registration is permissible. Based on the established UN Space Law, registration practice was subject to some adaptions due to technical developments and legal challenges. After the privatization of the major international satellite organizations, a number of non-registrations had to be faced. The state actors reacted with the UN Registration Practice Resolution of 2007 as elaborated in the Legal Subcommittee of UNCOPUOS, the Committee for the Peaceful Use of Outer Space. In this context an UNOOSA Registration Information

  3. State registration and inspection programs for particle accelerators

    International Nuclear Information System (INIS)

    Bailey, E.D.

    1976-01-01

    The Suggested State Regulations for Control of Radiation(SSRCR) are recommended by the Council of State Governments and the National Conference of Radiation Control Program Directors as the model regulations which states should adopt in order to have adequate regulation and uniformity from state to state. These regulations are used as a basis for reviewing the current status of accelerator regulation in each state. The SSRCR does contain a separate part for registration (Part B--Registration of Radiation Machine Facilities and Services) and a separate part (Part I--Radiation Safety Requirements for Particle Accelerators) with specific requirements for the possession and use of accelerators. In addition, medical accelerators have additional requirements in Part F--X-Rays in The Heating Acts. These regulations specify requirements related to limitations of use, shielding and safety design requirements, control and interlock systems, warning devices, operating procedures, radiation monitoring, and calibration of medical accelerators

  4. Higher Mortality in registrants with sudden model for end-stage liver disease increase: Disadvantaged by the current allocation policy.

    Science.gov (United States)

    Massie, Allan B; Luo, Xun; Alejo, Jennifer L; Poon, Anna K; Cameron, Andrew M; Segev, Dorry L

    2015-05-01

    Liver allocation is based on current Model for End-Stage Liver Disease (MELD) scores, with priority in the case of a tie being given to those waiting the longest with a given MELD score. We hypothesized that this priority might not reflect risk: registrants whose MELD score has recently increased receive lower priority but might have higher wait-list mortality. We studied wait-list and posttransplant mortality in 69,643 adult registrants from 2002 to 2013. By likelihood maximization, we empirically defined a MELD spike as a MELD increase ≥ 30% over the previous 7 days. At any given time, only 0.6% of wait-list patients experienced a spike; however, these patients accounted for 25% of all wait-list deaths. Registrants who reached a given MELD score after a spike had higher wait-list mortality in the ensuing 7 days than those with the same resulting MELD score who did not spike, but they had no difference in posttransplant mortality. The spike-associated wait-list mortality increase was highest for registrants with medium MELD scores: specifically, 2.3-fold higher (spike versus no spike) for a MELD score of 10, 4.0-fold higher for a MELD score of 20, and 2.5-fold higher for a MELD score of 30. A model incorporating the MELD score and spikes predicted wait-list mortality risk much better than a model incorporating only the MELD score. Registrants with a sudden MELD increase have a higher risk of short-term wait-list mortality than is indicated by their current MELD score but have no increased risk of posttransplant mortality; allocation policy should be adjusted accordingly. © 2015 American Association for the Study of Liver Diseases.

  5. Language proficiency and nursing registration.

    Science.gov (United States)

    Müller, Amanda

    2016-02-01

    This discussion paper focuses on English proficiency standards for nursing registration in Australia, how Australia has dealt with the issue of language proficiency, and the factors which have led to the establishment of the current language standards. Also, this paper will provide a comparison of the two language tests that are currently accepted in Australia (OET and IELTS), including the appropriateness of these tests and the minimum standards used. The paper will also examine the use of educational background as an indicator of language proficiency. Finally, communication-based complaints in the post-registration environment will be explored, and some discussion will be provided about why pre-registration measures might have failed to prevent such problematic situations from occurring. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. 78 FR 5501 - Manufacturer of Controlled Substances; Notice of Registration; Cerilliant Corporation

    Science.gov (United States)

    2013-01-25

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration; Cerilliant Corporation By Notice dated August 17, 2012, and published in the Federal Register on August 29, 2012, 77 FR 52366, Cerilliant Corporation, 811 Paloma Drive, Suite A, Round...

  7. 77 FR 40087 - Manufacturer of Controlled Substances; Notice of Registration; Cerilliant Corporation

    Science.gov (United States)

    2012-07-06

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration; Cerilliant Corporation By Notice dated March 23, 2012, and published in the Federal Register on April 2, 2012, 77 FR 19717, Cerilliant Corporation, 811 Paloma Drive, Suite A, Round...

  8. 78 FR 33442 - Manufacturer of Controlled Substances; Notice of Registration; Cerilliant Corporation

    Science.gov (United States)

    2013-06-04

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration; Cerilliant Corporation By Notice dated January 14, 2013, and published in the Federal Register on January 25, 2013, 78 FR 5499, Cerilliant Corporation, 811 Paloma Drive, Suite A, Round...

  9. 77 FR 24987 - Manufacturer of Controlled Substances; Notice of Registration; Cerilliant Corporation

    Science.gov (United States)

    2012-04-26

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration; Cerilliant Corporation By Notice dated January 5, 2012, and published in the Federal Register on January 17, 2012, 77 FR 2321, Cerilliant Corporation, 811 Paloma Drive, Suite A, Round...

  10. 78 FR 32459 - Manufacturer of Controlled Substances; Notice of Registration; Mallinckrodt, LLC.

    Science.gov (United States)

    2013-05-30

    ... plans to manufacture the listed controlled substances for internal use and for sale to other companies... ensure that the company's registration is consistent with the public interest. The investigation has included inspection and testing of the company's physical security systems, verification of the company's...

  11. 77 FR 70186 - Importer Of Controlled Substances; Notice Of Registration; Cerilliant Corporation

    Science.gov (United States)

    2012-11-23

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Importer Of Controlled Substances; Notice Of Registration; Cerilliant Corporation By Notice dated August 17, 2012, and published in the Federal Register on August 20, 2012, 77 FR 50162, Cerilliant Corporation, 811 Paloma Drive, Suite A, Round Rock, Texas 78665...

  12. 77 FR 31389 - Importer of Controlled Substances; Notice of Registration; Cerilliant Corporation

    Science.gov (United States)

    2012-05-25

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Importer of Controlled Substances; Notice of Registration; Cerilliant Corporation By Notice dated March 8, 2012, and published in the Federal Register on March 20, 2012, 77 FR 16261, Cerilliant Corporation, 811 Paloma Drive, Suite A, Round Rock, Texas 78665...

  13. 77 FR 21999 - Importer of Controlled Substances; Notice Of Registration; Cerilliant Corporation

    Science.gov (United States)

    2012-04-12

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Importer of Controlled Substances; Notice Of Registration; Cerilliant Corporation By Notice dated January 6, 2012, and published in the Federal Register on January 17, 2012, 77 FR 2321, Cerilliant Corporation, 811 Paloma Drive, Suite A, Round Rock, Texas 78665...

  14. 78 FR 64021 - Manufacturer of Controlled Substances; Notice of Registration; Chemtos, LLC

    Science.gov (United States)

    2013-10-25

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration; Chemtos, LLC By Notice dated June 18, 2013, and published in the Federal Register on July 1, 2013, 78 FR 39340, Chemtos, LLC., 14101 W. Highway 290, Building 2000B, Austin, Texas...

  15. 77 FR 75671 - Manufacturer of Controlled Substances; Notice of Registration; Chemtos, LLC

    Science.gov (United States)

    2012-12-21

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration; Chemtos, LLC By Notice dated July 30, 2012, and published in the Federal Register on August 7, 2012, 77 FR 47116, Chemtos, LLC, 14101 W. Highway 290, Building 2000B, Austin, Texas...

  16. Image Registration: A Necessary Evil

    Science.gov (United States)

    Bell, James; McLachlan, Blair; Hermstad, Dexter; Trosin, Jeff; George, Michael W. (Technical Monitor)

    1995-01-01

    Registration of test and reference images is a key component of nearly all PSP data reduction techniques. This is done to ensure that a test image pixel viewing a particular point on the model is ratioed by the reference image pixel which views the same point. Typically registration is needed to account for model motion due to differing airloads when the wind-off and wind-on images are taken. Registration is also necessary when two cameras are used for simultaneous acquisition of data from a dual-frequency paint. This presentation will discuss the advantages and disadvantages of several different image registration techniques. In order to do so, it is necessary to propose both an accuracy requirement for image registration and a means for measuring the accuracy of a particular technique. High contrast regions in the unregistered images are most sensitive to registration errors, and it is proposed that these regions be used to establish the error limits for registration. Once this is done, the actual registration error can be determined by locating corresponding points on the test and reference images, and determining how well a particular registration technique matches them. An example of this procedure is shown for three transforms used to register images of a semispan model. Thirty control points were located on the model. A subset of the points were used to determine the coefficients of each registration transform, and the error with which each transform aligned the remaining points was determined. The results indicate the general superiority of a third-order polynomial over other candidate transforms, as well as showing how registration accuracy varies with number of control points. Finally, it is proposed that image registration may eventually be done away with completely. As more accurate image resection techniques and more detailed model surface grids become available, it will be possible to map raw image data onto the model surface accurately. Intensity

  17. 77 FR 16264 - Manufacturer of Controlled Substances, Notice of Registration; Johnson Matthey Pharmaceutical...

    Science.gov (United States)

    2012-03-20

    ..., Notice of Registration; Johnson Matthey Pharmaceutical Materials Inc. By Notice dated November 18, 2011... Pharmaceutical Materials Inc., Pharmaceutical Service, 25 Patton Road, Devens, Massachusetts 01434, made... Matthey Pharmaceutical Materials Inc. to manufacture the listed basic classes of controlled substances is...

  18. 77 FR 30025 - Importer of Controlled Substances; Notice of Registration; Formulation Technologies, LLC

    Science.gov (United States)

    2012-05-21

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Importer of Controlled Substances; Notice of Registration; Formulation Technologies, LLC By Notice dated January 26, 2012, and published in the Federal..., Austin, Texas 78758, made application by renewal to the Drug Enforcement Administration (DEA) to be...

  19. 78 FR 15975 - Manufacturer of Controlled Substances, Notice of Registration; Johnson Matthey, Inc...

    Science.gov (United States)

    2013-03-13

    ..., Notice of Registration; Johnson Matthey, Inc., Pharmaceuticals Materials By Notice dated November 1, 2012, and published in the Federal Register on November 9, 2012, 77 FR 67397, Johnson Matthey, Inc...) II The company plans to manufacture the listed controlled substances in bulk for distribution and...

  20. 77 FR 30028 - Manufacturer of Controlled Substances; Notice of Registration; Johnson Matthey, Inc...

    Science.gov (United States)

    2012-05-21

    ...; Notice of Registration; Johnson Matthey, Inc., Pharmaceuticals Materials By Notice dated January 6, 2012, and published in the Federal Register on January 17, 2012, 77 FR 2324, Johnson Matthey, Inc... (9333) II The company plans to manufacture the listed controlled substances in bulk for sale to its...

  1. 78 FR 5499 - Manufacturer of Controlled Substances; Notice of Registration; Johnson Matthey, Inc.

    Science.gov (United States)

    2013-01-25

    ...; Notice of Registration; Johnson Matthey, Inc. By Notice dated May 9, 2012, and published in the Federal Register on May 21, 2012, 77 FR 30026, Johnson Matthey, Inc., Custom Pharmaceuticals Department, 2003 Nolte... substance listed in schedule II. The company plans to manufacture the listed controlled substance for sale...

  2. 78 FR 19016 - Importer of Controlled Substances; Notice of Registration; Johnson Matthey, Inc.

    Science.gov (United States)

    2013-03-28

    ... Registration; Johnson Matthey, Inc. By Notice dated November 19, 2012, and published in the Federal Register on November 27, 2012, 77 FR 70824, Johnson Matthey, Inc., Pharmaceutical Materials, 2003 Nolte Drive, West... Concentrate (9670) II The company plans to import the listed controlled substances as raw materials, to be...

  3. 77 FR 16262 - Importer of Controlled Substances, Notice of Registration; Johnson Matthey, Inc., Pharmaceutical...

    Science.gov (United States)

    2012-03-20

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Importer of Controlled Substances, Notice of Registration; Johnson Matthey, Inc., Pharmaceutical Materials By Notice dated December 2, 2011, and published in the Federal Register on December 12, 2011, 76 FR 77253, Johnson Matthey, Inc., Pharmaceutical...

  4. 75 FR 76756 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2010-12-09

    ..., 2010, (75 FR 47029), Johnson Matthey Pharma Services, 70 Flagship Drive, North Andover, Massachusetts... that the registration of Johnson Matthey Pharma Services to manufacture the listed basic classes of... Matthey Pharma Services to ensure that the company's registration is consistent with the public interest...

  5. 76 FR 51402 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2011-08-18

    ..., 2011, 76 FR 25376, Johnson Matthey Pharma Services, 70 Flagship Drive, North Andover, Massachusetts... that the registration of Johnson Matthey Pharma Services to manufacture the listed basic classes of... Matthey Pharma Services to ensure that the company's registration is consistent with the public interest...

  6. 77 FR 55503 - Importer of Controlled Substances; Notice of Registration; Cambrex Charles City, Inc.

    Science.gov (United States)

    2012-09-10

    ... company plans to import the listed controlled substances for internal use, and to manufacture bulk... company's registration is consistent with the public interest. The investigation has included inspection and testing of the company's physical security systems, verification of the company's compliance with...

  7. 77 FR 50163 - Importer of Controlled Substances; Notice of Registration; Catalent Pharma Solutions, Inc.

    Science.gov (United States)

    2012-08-20

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Importer of Controlled Substances; Notice of Registration; Catalent Pharma Solutions, Inc. Correction In notice document 2012-19202 appearing on page 47114 in the issue of Tuesday, August 7, 2012, make the following correction: On page 47114, in the first...

  8. CO-REGISTRATION OF PHOTOGRAMMETRIC AND LIDAR DATA: METHODOLOGY AND CASE STUDY

    Directory of Open Access Journals (Sweden)

    Mwafag Ghanma

    2004-07-01

    Full Text Available Registration activities combine data from different sources in order to attain higher accuracy and derive more information than available from one source. The increasing availability of a wide variety of sensors capable of capturing high quality and complementary data requires parallel efforts for developing accurate and robust registration techniques. Currently, photogrammetric and LIDAR systems are being incorporated in a wide spectrum of mapping applica¬tions such as city modeling, surface reconstruction, and object recognition. Photogrammetric processing of overlapping imagery provides accurate information regarding object space break-lines in addition to an explicit semantic description of the photographed objects. On the other hand, LIDAR systems supply dense geometric surface information in the form of non-selective points. Considering the properties of photogrammetric and LIDAR data, it is clear that the two technologies provide complementary information. However, the synergic characteristics of both systems can be fully utilized only after successful registration of the photogrammetric and LIDAR data relative to a common reference frame. The registration methodology has to deal with three issues: registration primitives, transformation function, and similarity measure. This paper presents two methodologies for utilizing straight-line features derived from both datasets as the registration primitives. The first methodology directly incorporates the LIDAR lines as control information in the photogrammetric triangulation. The second methodology starts by generating a photogrammetric model relative to an arbitrary datum. Then, LIDAR features are used as control information for the absolute orientation of the photogram¬metric model. In addition to the registration methodologies, the paper presents a comparative analysis between two approaches for extracting linear features from raw and processed/interpolated LIDAR data. Also, a comparative

  9. 78 FR 12104 - Manufacturer of Controlled Substances; Notice of Registration; INB Hauser Pharmaceutical Services...

    Science.gov (United States)

    2013-02-21

    ...; Notice of Registration; INB Hauser Pharmaceutical Services, Inc. By Notice dated November 1, 2012, and published in the Federal Register on November 9, 2012, 77 FR 67398, InB Hauser Pharmaceutical Services, Inc... Hauser Pharmaceutical Services, Inc., to manufacture the listed basic class of controlled substance is...

  10. Real-time CT-video registration for continuous endoscopic guidance

    Science.gov (United States)

    Merritt, Scott A.; Rai, Lav; Higgins, William E.

    2006-03-01

    Previous research has shown that CT-image-based guidance could be useful for the bronchoscopic assessment of lung cancer. This research drew upon the registration of bronchoscopic video images to CT-based endoluminal renderings of the airway tree. The proposed methods either were restricted to discrete single-frame registration, which took several seconds to complete, or required non-real-time buffering and processing of video sequences. We have devised a fast 2D/3D image registration method that performs single-frame CT-Video registration in under 1/15th of a second. This allows the method to be used for real-time registration at full video frame rates without significantly altering the physician's behavior. The method achieves its speed through a gradient-based optimization method that allows most of the computation to be performed off-line. During live registration, the optimization iteratively steps toward the locally optimal viewpoint at which a CT-based endoluminal view is most similar to a current bronchoscopic video frame. After an initial registration to begin the process (generally done in the trachea for bronchoscopy), subsequent registrations are performed in real-time on each incoming video frame. As each new bronchoscopic video frame becomes available, the current optimization is initialized using the previous frame's optimization result, allowing continuous guidance to proceed without manual re-initialization. Tests were performed using both synthetic and pre-recorded bronchoscopic video. The results show that the method is robust to initialization errors, that registration accuracy is high, and that continuous registration can proceed on real-time video at >15 frames per sec. with minimal user-intervention.

  11. 78 FR 46371 - Importer of Controlled Substances; Notice of Registration; Almac Clinical Services, Inc.

    Science.gov (United States)

    2013-07-31

    ... Register on April 19, 2013, 78 FR 23594, Almac Clinical Services, Inc., (ACSI), 25 Fretz Road, Souderton... registration of Almac Clinical Services, Inc., (ACSI) to import the basic classes of controlled substances is..., conventions, or protocols in effect on May 1, 1971. DEA has investigated Almac Clinical Services, Inc., (ACSI...

  12. Registration of Laser Scanning Point Clouds: A Review

    Science.gov (United States)

    Cheng, Liang; Chen, Song; Xu, Hao; Wu, Yang; Li, Manchun

    2018-01-01

    The integration of multi-platform, multi-angle, and multi-temporal LiDAR data has become important for geospatial data applications. This paper presents a comprehensive review of LiDAR data registration in the fields of photogrammetry and remote sensing. At present, a coarse-to-fine registration strategy is commonly used for LiDAR point clouds registration. The coarse registration method is first used to achieve a good initial position, based on which registration is then refined utilizing the fine registration method. According to the coarse-to-fine framework, this paper reviews current registration methods and their methodologies, and identifies important differences between them. The lack of standard data and unified evaluation systems is identified as a factor limiting objective comparison of different methods. The paper also describes the most commonly-used point cloud registration error analysis methods. Finally, avenues for future work on LiDAR data registration in terms of applications, data, and technology are discussed. In particular, there is a need to address registration of multi-angle and multi-scale data from various newly available types of LiDAR hardware, which will play an important role in diverse applications such as forest resource surveys, urban energy use, cultural heritage protection, and unmanned vehicles.

  13. 75 FR 55671 - Financial Assistance Use of Universal Identifier and Central Contractor Registration

    Science.gov (United States)

    2010-09-14

    ... of Universal Identifier and Central Contractor Registration AGENCY: Office of Federal Financial...) numbers and maintain current registrations in the Central Contractor Registration (CCR) database. An... CONTRACTOR REGISTRATION Sec. Subpart A--General 25.100 Purposes of this part. 25.105 Types of awards to which...

  14. Fiducial registration error as a statistical process control metric in image-guided radiotherapy with prostatic markers

    International Nuclear Information System (INIS)

    Ung, M.N.; Wee, Leonard

    2010-01-01

    Full text: Portal imaging of implanted fiducial markers has been in use for image-guided radiotherapy (TORT) of prostate cancer, with ample attention to localization accuracy and organ motion. The geometric uncertainties in point-based rigid-body (PBRB) image registration during localization of prostate fiducial markers can be quantified in terms of a fiducial registration error (FRE). Statistical process control charts for individual patients can be designed to identify potentially significant deviation of FRE from expected behaviour. In this study, the aim was to retrospectively apply statistical process control methods to FREs in 34 individuals to identify parameters that may impact on the process stability in image-based localization. A robust procedure for estimating control parameters, control lim its and fixed tolerance levels from a small number of initial observations has been proposed and discussed. Four distinct types of qualitative control chart behavior have been observed. Probable clinical factors leading to IORT process instability are discussed in light of the control chart behaviour. Control charts have been shown to be a useful decision-making tool for detecting potentially out-of control processes on an individual basis. It can sensitively identify potential problems that warrant more detailed investigation in the 10RT of prostate cancer.

  15. Clinical trial registration in oral health journals.

    Science.gov (United States)

    Smaïl-Faugeron, V; Fron-Chabouis, H; Durieux, P

    2015-03-01

    Prospective registration of randomized controlled trials (RCTs) represents the best solution to reporting bias. The extent to which oral health journals have endorsed and complied with RCT registration is unknown. We identified journals publishing RCTs in dentistry, oral surgery, and medicine in the Journal Citation Reports. We classified journals into 3 groups: journals requiring or recommending trial registration, journals referring indirectly to registration, and journals providing no reference to registration. For the 5 journals with the highest 2012 impact factors in each group, we assessed whether RCTs with results published in 2013 had been registered. Of 78 journals examined, 32 (41%) required or recommended trial registration, 19 (24%) referred indirectly to registration, and 27 (35%) provided no reference to registration. We identified 317 RCTs with results published in the 15 selected journals in 2013. Overall, 73 (23%) were registered in a trial registry. Among those, 91% were registered retrospectively and 32% did not report trial registration in the published article. The proportion of trials registered was not significantly associated with editorial policies: 29% with results in journals that required or recommended registration, 15% in those that referred indirectly to registration, and 21% in those providing no reference to registration (P = 0.05). Less than one-quarter of RCTs with results published in a sample of oral health journals were registered with a public registry. Improvements are needed with respect to how journals inform and require their authors to register their trials. © International & American Associations for Dental Research.

  16. Development of the cancer registration system in Belarus

    International Nuclear Information System (INIS)

    Okeanov, A.E.; Polyakov, S.M.; Sobolev, A.V.; Winkelmann, R.A.; Storm, H.H.

    1996-01-01

    Cancer registration was established in Belarus in 1953, however was not complete until the 1970's. In 1973 a computerized central cancer registry was established (files available only from 1978) based on coded and anonymous information received from each of the 12 oncological dispensaries in the country. In 1985 a computer system of dispensary control for cancer patients was set up in the oncological dispensaries in Belarus, whereby identification of individual cancer patients in the cancer registry was made possible. The Belarussian cancer registry records all cases of cancer including those of the lymph-hematopoietic system, and carcinoma in situ. The registry is person-based with information on all tumors and their treatment in a given individual. Coding and classification is carried out in accordance with ICD-9. For histology a local classification is used. Currently the registration system is under modernization in order to achieve full correspondence with internationally accepted standards and for the purpose of easy linkage to the Belarussian Chernobyl Registry

  17. Surface-based prostate registration with biomechanical regularization

    Science.gov (United States)

    van de Ven, Wendy J. M.; Hu, Yipeng; Barentsz, Jelle O.; Karssemeijer, Nico; Barratt, Dean; Huisman, Henkjan J.

    2013-03-01

    Adding MR-derived information to standard transrectal ultrasound (TRUS) images for guiding prostate biopsy is of substantial clinical interest. A tumor visible on MR images can be projected on ultrasound by using MRUS registration. A common approach is to use surface-based registration. We hypothesize that biomechanical modeling will better control deformation inside the prostate than a regular surface-based registration method. We developed a novel method by extending a surface-based registration with finite element (FE) simulation to better predict internal deformation of the prostate. For each of six patients, a tetrahedral mesh was constructed from the manual prostate segmentation. Next, the internal prostate deformation was simulated using the derived radial surface displacement as boundary condition. The deformation field within the gland was calculated using the predicted FE node displacements and thin-plate spline interpolation. We tested our method on MR guided MR biopsy imaging data, as landmarks can easily be identified on MR images. For evaluation of the registration accuracy we used 45 anatomical landmarks located in all regions of the prostate. Our results show that the median target registration error of a surface-based registration with biomechanical regularization is 1.88 mm, which is significantly different from 2.61 mm without biomechanical regularization. We can conclude that biomechanical FE modeling has the potential to improve the accuracy of multimodal prostate registration when comparing it to regular surface-based registration.

  18. Deformable Registration for Longitudinal Breast MRI Screening.

    Science.gov (United States)

    Mehrabian, Hatef; Richmond, Lara; Lu, Yingli; Martel, Anne L

    2018-04-13

    MRI screening of high-risk patients for breast cancer provides very high sensitivity, but with a high recall rate and negative biopsies. Comparing the current exam to prior exams reduces the number of follow-up procedures requested by radiologists. Such comparison, however, can be challenging due to the highly deformable nature of breast tissues. Automated co-registration of multiple scans has the potential to aid diagnosis by providing 3D images for side-by-side comparison and also for use in CAD systems. Although many deformable registration techniques exist, they generally have a large number of parameters that need to be optimized and validated for each new application. Here, we propose a framework for such optimization and also identify the optimal input parameter set for registration of 3D T 1 -weighted MRI of breast using Elastix, a widely used and freely available registration tool. A numerical simulation study was first conducted to model the breast tissue and its deformation through finite element (FE) modeling. This model generated the ground truth for evaluating the registration accuracy by providing the deformation of each voxel in the breast volume. An exhaustive search was performed over various values of 7 registration parameters (4050 different combinations of parameters were assessed) and the optimum parameter set was determined. This study showed that there was a large variation in the registration accuracy of different parameter sets ranging from 0.29 mm to 2.50 mm in median registration error and 3.71 mm to 8.90 mm in 95 percentile of the registration error. Mean registration errors of 0.32 mm, 0.29 mm, and 0.30 mm and 95 percentile errors of 3.71 mm, 5.02 mm, and 4.70 mm were obtained by the three best parameter sets. The optimal parameter set was applied to consecutive breast MRI scans of 13 patients. A radiologist identified 113 landmark pairs (~ 11 per patient) which were used to assess registration accuracy. The results demonstrated that

  19. Automatic block-matching registration to improve lung tumor localization during image-guided radiotherapy

    Science.gov (United States)

    Robertson, Scott Patrick

    To improve relatively poor outcomes for locally-advanced lung cancer patients, many current efforts are dedicated to minimizing uncertainties in radiotherapy. This enables the isotoxic delivery of escalated tumor doses, leading to better local tumor control. The current dissertation specifically addresses inter-fractional uncertainties resulting from patient setup variability. An automatic block-matching registration (BMR) algorithm is implemented and evaluated for the purpose of directly localizing advanced-stage lung tumors during image-guided radiation therapy. In this algorithm, small image sub-volumes, termed "blocks", are automatically identified on the tumor surface in an initial planning computed tomography (CT) image. Each block is independently and automatically registered to daily images acquired immediately prior to each treatment fraction. To improve the accuracy and robustness of BMR, this algorithm incorporates multi-resolution pyramid registration, regularization with a median filter, and a new multiple-candidate-registrations technique. The result of block-matching is a sparse displacement vector field that models local tissue deformations near the tumor surface. The distribution of displacement vectors is aggregated to obtain the final tumor registration, corresponding to the treatment couch shift for patient setup correction. Compared to existing rigid and deformable registration algorithms, the final BMR algorithm significantly improves the overlap between target volumes from the planning CT and registered daily images. Furthermore, BMR results in the smallest treatment margins for the given study population. However, despite these improvements, large residual target localization errors were noted, indicating that purely rigid couch shifts cannot correct for all sources of inter-fractional variability. Further reductions in treatment uncertainties may require the combination of high-quality target localization and adaptive radiotherapy.

  20. 78 FR 33443 - Manufacturer of Controlled Substances; Notice of Registration; Norac, Inc.

    Science.gov (United States)

    2013-06-04

    ... Register on November 27, 2012, 77 FR 70825, Norac, Inc., DBA: Norac Pharma, 405 S. Motor Avenue, Azusa... the registration of Norac, Inc., DBA: Norac Pharma, to manufacture the listed basic classes of...., DBA: Norac Pharma, to ensure that the company's registration is consistent with the public interest...

  1. Study of national registration systems for health records of radiation workers. National radiation dose registration system

    International Nuclear Information System (INIS)

    Nakagawa, Haruo; Kanda, Keiji

    1999-01-01

    A national radiation dose registration system is proposed in this paper. In Japan, only one radiation dose registration system is partly effective. It is applied for workers in nuclear power plants which are under control of regulatory laws for nuclear reactors. The total system was proposed previously by the Committee for Compensation Claims of Nuclear Accidents. The reason for the delay in establishing a registration system for all radiation workers is supposedly a lack of effort to adjust differences among items in radiation protection laws and the promotion of public acceptance to atomic power. Items about dose recordings, record keeping and dose-record reporting in all of the radiation regulatory laws are compared to each other, and items were extracted for revision. (author)

  2. Propagation of registration uncertainty during multi-fraction cervical cancer brachytherapy

    Science.gov (United States)

    Amir-Khalili, A.; Hamarneh, G.; Zakariaee, R.; Spadinger, I.; Abugharbieh, R.

    2017-10-01

    Multi-fraction cervical cancer brachytherapy is a form of image-guided radiotherapy that heavily relies on 3D imaging during treatment planning, delivery, and quality control. In this context, deformable image registration can increase the accuracy of dosimetric evaluations, provided that one can account for the uncertainties associated with the registration process. To enable such capability, we propose a mathematical framework that first estimates the registration uncertainty and subsequently propagates the effects of the computed uncertainties from the registration stage through to the visualizations, organ segmentations, and dosimetric evaluations. To ensure the practicality of our proposed framework in real world image-guided radiotherapy contexts, we implemented our technique via a computationally efficient and generalizable algorithm that is compatible with existing deformable image registration software. In our clinical context of fractionated cervical cancer brachytherapy, we perform a retrospective analysis on 37 patients and present evidence that our proposed methodology for computing and propagating registration uncertainties may be beneficial during therapy planning and quality control. Specifically, we quantify and visualize the influence of registration uncertainty on dosimetric analysis during the computation of the total accumulated radiation dose on the bladder wall. We further show how registration uncertainty may be leveraged into enhanced visualizations that depict the quality of the registration and highlight potential deviations from the treatment plan prior to the delivery of radiation treatment. Finally, we show that we can improve the transfer of delineated volumetric organ segmentation labels from one fraction to the next by encoding the computed registration uncertainties into the segmentation labels.

  3. Registration Service

    CERN Multimedia

    GS Department

    2010-01-01

    Following a reorganization in Building 55, please note that the Registration Service is now organised as follows :  Ground floor: access cards (76903). 1st floor : registration of external firms’ personnel (76611 / 76622); car access stickers (76633); biometric registration (79710). Opening hours: 07-30 to 16-00 non-stop. GS-SEM Group General Infrastructure Services Department

  4. 77 FR 30027 - Manufacturer of Controlled Substances; Notice of Registration; Siegfried (USA)

    Science.gov (United States)

    2012-05-21

    ...; Notice of Registration; Siegfried (USA) By Notice dated January 6, 2012, and published in the Federal Register on January 17, 2012, 77 FR 2323, Siegfried (USA), 33 Industrial Park Road, Pennsville, New Jersey... U.S.C. 823(a) and determined that the registration of Siegfried (USA), to manufacture the listed...

  5. 21 CFR 1301.13 - Application for registration; time for application; expiration date; registration for independent...

    Science.gov (United States)

    2010-04-01

    ... dispose any substance or class for which not registered. Schedules II-V: except a person registered to... to manufacture a basic class of controlled substance listed in Schedule II shall include the... registration to conduct research with any basic class of controlled substance listed in Schedule II shall...

  6. 78 FR 23595 - Importer of Controlled Substances; Notice of Registration; GE Healthcare

    Science.gov (United States)

    2013-04-19

    ... Registration; GE Healthcare By Notice dated January 31, 2013, and published in the Federal Register on February 6, 2013, 78 FR 8583, GE Healthcare, 3350 North Ridge Avenue, Arlington Heights, Illinois 60004-1412... considered the factors in 21 U.S.C. 823(a) and 952(a) and determined that the registration of GE Healthcare...

  7. 78 FR 54914 - Importer of Controlled Substances; Notice of Registration; GE Healthcare

    Science.gov (United States)

    2013-09-06

    ... Registration; GE Healthcare By Notice dated June 7, 2013, and published in the Federal Register on June 18, 2013, 78 FR 36594, GE Healthcare, 3350 North Ridge Avenue, Arlington Heights, Illinois 60004-1412, made... factors in 21 U.S.C. 823(a) and 952(a) and determined that the registration of GE Healthcare to import the...

  8. Overlay improvement by exposure map based mask registration optimization

    Science.gov (United States)

    Shi, Irene; Guo, Eric; Chen, Ming; Lu, Max; Li, Gordon; Li, Rivan; Tian, Eric

    2015-03-01

    Along with the increased miniaturization of semiconductor electronic devices, the design rules of advanced semiconductor devices shrink dramatically. [1] One of the main challenges of lithography step is the layer-to-layer overlay control. Furthermore, DPT (Double Patterning Technology) has been adapted for the advanced technology node like 28nm and 14nm, corresponding overlay budget becomes even tighter. [2][3] After the in-die mask registration (pattern placement) measurement is introduced, with the model analysis of a KLA SOV (sources of variation) tool, it's observed that registration difference between masks is a significant error source of wafer layer-to-layer overlay at 28nm process. [4][5] Mask registration optimization would highly improve wafer overlay performance accordingly. It was reported that a laser based registration control (RegC) process could be applied after the pattern generation or after pellicle mounting and allowed fine tuning of the mask registration. [6] In this paper we propose a novel method of mask registration correction, which can be applied before mask writing based on mask exposure map, considering the factors of mask chip layout, writing sequence, and pattern density distribution. Our experiment data show if pattern density on the mask keeps at a low level, in-die mask registration residue error in 3sigma could be always under 5nm whatever blank type and related writer POSCOR (position correction) file was applied; it proves random error induced by material or equipment would occupy relatively fixed error budget as an error source of mask registration. On the real production, comparing the mask registration difference through critical production layers, it could be revealed that registration residue error of line space layers with higher pattern density is always much larger than the one of contact hole layers with lower pattern density. Additionally, the mask registration difference between layers with similar pattern density

  9. 21 CFR 710.6 - Notification of registrant; cosmetic product establishment registration number.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Notification of registrant; cosmetic product... OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.6 Notification of registrant; cosmetic product establishment registration number. The...

  10. Block assembly for global registration of building scans

    KAUST Repository

    Yan, Feilong; Nan, Liangliang; Wonka, Peter

    2016-01-01

    We propose a framework for global registration of building scans. The first contribution of our work is to detect and use portals (e.g., doors and windows) to improve the local registration between two scans. Our second contribution is an optimization based on a linear integer programming formulation. We abstract each scan as a block and model the blocks registration as an optimization problem that aims at maximizing the overall matching score of the entire scene. We propose an efficient solution to this optimization problem by iteratively detecting and adding local constraints. We demonstrate the effectiveness of the proposed method on buildings of various styles and that our approach is superior to the current state of the art.

  11. Block assembly for global registration of building scans

    KAUST Repository

    Yan, Feilong

    2016-11-11

    We propose a framework for global registration of building scans. The first contribution of our work is to detect and use portals (e.g., doors and windows) to improve the local registration between two scans. Our second contribution is an optimization based on a linear integer programming formulation. We abstract each scan as a block and model the blocks registration as an optimization problem that aims at maximizing the overall matching score of the entire scene. We propose an efficient solution to this optimization problem by iteratively detecting and adding local constraints. We demonstrate the effectiveness of the proposed method on buildings of various styles and that our approach is superior to the current state of the art.

  12. 16 CFR 1130.8 - Requirements for Web site registration or alternative e-mail registration.

    Science.gov (United States)

    2010-01-01

    ... registration. (a) Link to registration page. The manufacturer's Web site, or other Web site established for the... web page that goes directly to “Product Registration.” (b) Purpose statement. The registration page... registration page. The Web site registration page shall request only the consumer's name, address, telephone...

  13. Industry's View on Using Quality Control, Biorelevant, and Clinically Relevant Dissolution Tests for Pharmaceutical Development, Registration, and Commercialization.

    Science.gov (United States)

    Grady, Haiyan; Elder, David; Webster, Gregory K; Mao, Yun; Lin, Yiqing; Flanagan, Talia; Mann, James; Blanchard, Andy; Cohen, Michael J; Lin, Judy; Kesisoglou, Filippos; Hermans, Andre; Abend, Andreas; Zhang, Limin; Curran, David

    2018-01-01

    This article intends to summarize the current views of the IQ Consortium Dissolution Working Group, which comprises various industry companies, on the roles of dissolution testing throughout pharmaceutical product development, registration, commercialization, and beyond. Over the past 3 decades, dissolution testing has evolved from a routine and straightforward test as a component of end-product release into a comprehensive set of tools that the developer can deploy at various stages of the product life cycle. The definitions of commonly used dissolution approaches, how they relate to one another and how they may be applied in modern drug development, and life cycle management is described in this article. Specifically, this article discusses the purpose, advantages, and limitations of quality control, biorelevant, and clinically relevant dissolution methods. Copyright © 2018 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  14. 78 FR 64016 - Importer of Controlled Substances, Notice of Registration, Boehringer Ingelheim Chemicals

    Science.gov (United States)

    2013-10-25

    ... Registration, Boehringer Ingelheim Chemicals By Notice dated June 18, 2013, and published in the Federal Register on July 1, 2013, 78 FR 39337, Boehringer Ingelheim Chemicals, 2820 N. Normandy Drive, Petersburg...) and determined that the registration of Boehringer Ingelheim Chemicals is consistent with the public...

  15. Summer Camp July 2017 - Registration

    CERN Multimedia

    EVE et École

    2017-01-01

    The CERN Staff Association’s Summer Camp will be open for children from 4 to 6 years old during four weeks, from 3 to 28 July. Registration is offered on a weekly basis for 450 CHF, lunch included. This year, the various activities will revolve around the theme of the Four Elements. Registration opened on 20 March 2017 for children currently attending the EVE and School of the Association. It will be open from 3 April for children of CERN Members of Personnel, and starting from 24 April for all other children. The general conditions are available on the website of the EVE and School of CERN Staff Association: http://nurseryschool.web.cern.ch. For further questions, please contact us by email at Summer.Camp@cern.ch.

  16. Variable current speed controller for eddy current motors

    Science.gov (United States)

    Gerth, H.L.; Bailey, J.M.; Casstevens, J.M.; Dixon, J.H.; Griffith, B.O.; Igou, R.E.

    1982-03-12

    A speed control system for eddy current motors is provided in which the current to the motor from a constant frequency power source is varied by comparing the actual motor speed signal with a setpoint speed signal to control the motor speed according to the selected setpoint speed. A three-phase variable voltage autotransformer is provided for controlling the voltage from a three-phase power supply. A corresponding plurality of current control resistors is provided in series with each phase of the autotransformer output connected to inputs of a three-phase motor. Each resistor is connected in parallel with a set of normally closed contacts of plurality of relays which are operated by control logic. A logic circuit compares the selected speed with the actual motor speed obtained from a digital tachometer monitoring the motor spindle speed and operated the relays to add or substract resistance equally in each phase of the motor input to vary the motor current to control the motor at the selected speed.

  17. 77 FR 24988 - Manufacturer of Controlled Substances; Notice of Registration; Johnson Matthey Inc.

    Science.gov (United States)

    2012-04-26

    .... DEA has investigated Johnson Matthey Inc. to ensure that the company's registration is consistent with...; Notice of Registration; Johnson Matthey Inc. By Notice dated November 21, 2011, and published in the Federal Register on November 29, 2011, 76 FR 73679, Johnson Matthey Inc., Pharmaceuticals Materials, 900...

  18. 77 FR 31388 - Importer of Controlled Substances; Notice of Registration; Meridian Medical Technologies

    Science.gov (United States)

    2012-05-25

    ... Registration; Meridian Medical Technologies By Notice dated March 23, 2012, and published in the Federal Register on April 2, 2012, 77 FR 19716, Meridian Medical Technologies, 2555 Hermelin Drive, St. Louis...) and 952(a), and determined that the registration of Meridian Medical Technologies to import the basic...

  19. Constrained non-rigid registration for whole body image registration: method and validation

    Science.gov (United States)

    Li, Xia; Yankeelov, Thomas E.; Peterson, Todd E.; Gore, John C.; Dawant, Benoit M.

    2007-03-01

    3D intra- and inter-subject registration of image volumes is important for tasks that include measurements and quantification of temporal/longitudinal changes, atlas-based segmentation, deriving population averages, or voxel and tensor-based morphometry. A number of methods have been proposed to tackle this problem but few of them have focused on the problem of registering whole body image volumes acquired either from humans or small animals. These image volumes typically contain a large number of articulated structures, which makes registration more difficult than the registration of head images, to which the vast majority of registration algorithms have been applied. To solve this problem, we have previously proposed an approach, which initializes an intensity-based non-rigid registration algorithm with a point based registration technique [1, 2]. In this paper, we introduce new constraints into our non-rigid registration algorithm to prevent the bones from being deformed inaccurately. Results we have obtained show that the new constrained algorithm leads to better registration results than the previous one.

  20. Mass preserving image registration

    DEFF Research Database (Denmark)

    Gorbunova, Vladlena; Sporring, Jon; Lo, Pechin Chien Pau

    2010-01-01

    The paper presents results the mass preserving image registration method in the Evaluation of Methods for Pulmonary Image Registration 2010 (EMPIRE10) Challenge. The mass preserving image registration algorithm was applied to the 20 image pairs. Registration was evaluated using four different...

  1. 77 FR 75672 - Manufacturer of Controlled Substances, Notice of Registration, Halo Pharmaceutical, Inc.

    Science.gov (United States)

    2012-12-21

    ..., Notice of Registration, Halo Pharmaceutical, Inc. By Notice dated July 30, 2012, and published in the Federal Register on August 7, 2012, 77 FR 47114, Halo Pharmaceutical, Inc., 30 North Jefferson Road... 21 U.S.C. 823(a), and determined that the registration of Halo Pharmaceutical, Inc., to manufacture...

  2. Fractional Regularization Term for Variational Image Registration

    Directory of Open Access Journals (Sweden)

    Rafael Verdú-Monedero

    2009-01-01

    Full Text Available Image registration is a widely used task of image analysis with applications in many fields. Its classical formulation and current improvements are given in the spatial domain. In this paper a regularization term based on fractional order derivatives is formulated. This term is defined and implemented in the frequency domain by translating the energy functional into the frequency domain and obtaining the Euler-Lagrange equations which minimize it. The new regularization term leads to a simple formulation and design, being applicable to higher dimensions by using the corresponding multidimensional Fourier transform. The proposed regularization term allows for a real gradual transition from a diffusion registration to a curvature registration which is best suited to some applications and it is not possible in the spatial domain. Results with 3D actual images show the validity of this approach.

  3. 78 FR 30333 - Manufacturer of Controlled Substances; Notice of Registration; Siegfried (Usa), Llc.

    Science.gov (United States)

    2013-05-22

    ...; Notice of Registration; Siegfried (Usa), Llc. By Notice dated November 19, 2012, and published in the Federal Register on November 27, 2012, 77 FR 70825, Siegfried (USA), LLC., 33 Industrial Park Road... 21 U.S.C. 823(a) and determined that the registration of Siegfried (USA), LLC., to manufacture the...

  4. 77 FR 16264 - Manufacturer of Controlled Substances, Notice of Registration; Halo Pharmaceutical Inc.

    Science.gov (United States)

    2012-03-20

    ..., Notice of Registration; Halo Pharmaceutical Inc. By Notice dated December 2, 2011, and published in the Federal Register on December 14, 2011, 76 FR 77850, Halo Pharmaceutical Inc., 30 North Jefferson Road... considered the factors in 21 U.S.C. 823(a) and determined that the registration of Halo Pharmaceutical Inc...

  5. 21 CFR 1301.36 - Suspension or revocation of registration; suspension of registration pending final order...

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Suspension or revocation of registration; suspension of registration pending final order; extension of registration pending final order. 1301.36... registration pending final order; extension of registration pending final order. (a) For any registration...

  6. Event Registration System for INR Linac

    International Nuclear Information System (INIS)

    Grekhov, O.V.; Drugakov, A.N.; Kiselev, Yu.V.

    2006-01-01

    The software of the Event registration system for the linear accelerators is described. This system allows receiving of the information on changes of operating modes of the accelerator and supervising of hundreds of key parameters of various systems of the accelerator. The Event registration system consists of the source and listeners of events. The sources of events are subroutines built in existing ACS Linac. The listeners of events are software Supervisor and Client ERS. They are used for warning the operator about change controlled parameter of the accelerator

  7. 21 CFR 710.8 - Misbranding by reference to registration or to registration number.

    Science.gov (United States)

    2010-04-01

    ... HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.8 Misbranding by reference to registration or to registration number. Registration of a cosmetic product... products by the Food and Drug Administration. Any representation in labeling or advertising that creates an...

  8. [Consideration about chemistry, manufacture and control (CMC) key problems in simplified registration of classical traditional Chinese medicine excellent prescriptions].

    Science.gov (United States)

    Wang, Zhi-Min; Liu, Ju-Yan; Liu, Xiao-Qian; Wang, De-Qin; Yan, Li-Hua; Zhu, Jin-Jin; Gao, Hui-Min; Li, Chun; Wang, Jin-Yu; Li, Chu-Yuan; Ni, Qing-Chun; Huang, Ji-Sheng; Lin, Juan

    2017-05-01

    As an outstanding representative of traditional Chinese medicine(TCM) prescriptions accumulated from famous TCM doctors' clinical experiences in past dynasties, classical TCM excellent prescriptions (cTCMeP) are the most valuable part of TCM system. To support the research and development of cTCMeP, a series of regulations and measures were issued to encourage its simplified registration. There is still a long-way to go because many key problems and puzzles about technology, registration and administration in cTCMeP R&D process are not resolved. Based on the analysis of registration and management regulations of botanical drug products in FDA of USA and Japan, and EMA of Europe, the possible key problems and countermeasures in chemistry, manufacture and control (CMC) of simplified registration of cTCMeP were analyzed on the consideration of its actual situation. The method of "reference decoction extract by traditional prescription" (RDETP) was firstly proposed as standard to evaluate the quality and preparation uniformity between the new developing product under simplified registration and traditional original usages of cTCMeP, instead of Standard Decoction method in Japan. "Totality of the evidence" approach, mass balance and bioassay/biological assay of cTCMeP were emphatically suggested to introduce to the quality uniformity evaluation system in the raw drug material, drug substance and final product between the modern product and traditional decoction. Copyright© by the Chinese Pharmaceutical Association.

  9. Anger, frustration, boredom and the Department of Motor Vehicles: Can negative emotions impede organ donor registration?

    Science.gov (United States)

    Siegel, Jason T; Tan, Cara N; Rosenberg, Benjamin D; Navarro, Mario A; Thomson, Andrew L; Lyrintzis, Elena A; Alvaro, Eusebio M; Jones, Natalie D

    2016-03-01

    The IIFF Model (Information, Immediate and Complete Registration Mechanism, Focused Engagement, Favorable Activation) offers a checklist of considerations for interventions seeking to influence organ donor registration behavior. One aspect of the model, favorable activation, recommends considering the emotional and motivational state of a potential donor registrant. Given that most donor registrations occur at the Department of Motor Vehicles (DMV), we considered whether emotions experienced while at the DMV could influence registration rates. The current research effort investigated the emotions people experience while visiting the DMV, explored whether these emotions are associated with donor registration intentions, and experimentally assessed whether DMV experiences influence donor registration. Three studies were conducted through Amazon's Mechanical Turk. In Study 1, we randomly assigned participants to either recall a prior DMV experience or to a comparison condition. Emotions associated with the recalled experiences were the dependent variable. Study 2 assessed the correlations between nine different emotions and donor registration intentions. Study 3 randomly assigned participants to recall a prior frustrating DMV experience or to a comparison condition. Intention to register to donate was the dependent variable. Study 1 found that recalling a prior DMV experience was associated with more negative and less positive emotions than the comparison condition. Study 2 found that increased levels of negative emotion could be problematic, as negative emotions were associated with decreased donor intentions. Study 3 found that recalling a frustrating DMV experience resulted in significantly lower intentions to register as an organ donor (vs. a control condition). Although not all DMV experiences are negative, these data indicated a relationship between the DMV and negative emotions; an association between negative emotions and lower donor registration intentions

  10. 78 FR 17231 - Importer of Controlled Substances, Notice of Registration, Watson Pharma, Inc.

    Science.gov (United States)

    2013-03-20

    ... Registration, Watson Pharma, Inc. By Notice dated November 5, 2012, and published in the Federal Register on November 13, 2012, 77 FR 67675, Watson Pharma, Inc., 2455 Wardlow Road, Corona, California 92880-2882, made.... 823(a) and Sec. 952(a) and determined that the registration of Watson Pharma, Inc., to import the...

  11. 78 FR 64019 - Manufacturer of Controlled Substances, Notice of Registration, Austin Pharma, LLC.

    Science.gov (United States)

    2013-10-25

    ..., Notice of Registration, Austin Pharma, LLC. By Notice dated May 14, 2013, and published in the Federal Register on May 22, 2013, 78 FR 30332, Austin Pharma, LLC., 811 Paloma Drive, Suite C, Round Rock, Texas... this drug code is authorized for this registration. On August 9, 2013, Austin Pharma, LLC., withdrew...

  12. CMOS current controlled fully balanced current conveyor

    International Nuclear Information System (INIS)

    Wang Chunhua; Zhang Qiujing; Liu Haiguang

    2009-01-01

    This paper presents a current controlled fully balanced second-generation current conveyor circuit (CF-BCCII). The proposed circuit has the traits of fully balanced architecture, and its X-Y terminals are current controllable. Based on the CFBCCII, two biquadratic universal filters are also proposed as its applications. The CFBCCII circuits and the two filters were fabricated with chartered 0.35-μm CMOS technology; with ±1.65 V power supply voltage, the total power consumption of the CFBCCII circuit is 3.6 mW. Comparisons between measured and HSpice simulation results are also given.

  13. 78 FR 64016 - Importer of Controlled Substances; Notice of Registration; Watson Pharma, Inc.

    Science.gov (United States)

    2013-10-25

    ... Registration; Watson Pharma, Inc. By Notice dated May 24, 2013, and published in the Federal Register on June 4, 2013, 78 FR 33440, Watson Pharma, Inc., 2455 Wardlow Road, Corona, California 92880-2882, made... in 21 U.S.C. 823(a) and 952(a) and determined that the registration of Watson Pharma, Inc., to import...

  14. Registration of eye reflection and scene images using an aspherical eye model.

    Science.gov (United States)

    Nakazawa, Atsushi; Nitschke, Christian; Nishida, Toyoaki

    2016-11-01

    This paper introduces an image registration algorithm between an eye reflection and a scene image. Although there are currently a large number of image registration algorithms, this task remains difficult due to nonlinear distortions at the eye surface and large amounts of noise, such as iris texture, eyelids, eyelashes, and their shadows. To overcome this issue, we developed an image registration method combining an aspherical eye model that simulates nonlinear distortions considering eye geometry and a two-step iterative registration strategy that obtains dense correspondence of the feature points to achieve accurate image registrations for the entire image region. We obtained a database of eye reflection and scene images featuring four subjects in indoor and outdoor scenes and compared the registration performance with different asphericity conditions. Results showed that the proposed approach can perform accurate registration with an average accuracy of 1.05 deg by using the aspherical cornea model. This work is relevant for eye image analysis in general, enabling novel applications and scenarios.

  15. Non-rigid image registration using bone growth model

    DEFF Research Database (Denmark)

    Bro-Nielsen, Morten; Gramkow, Claus; Kreiborg, Sven

    1997-01-01

    Non-rigid registration has traditionally used physical models like elasticity and fluids. These models are very seldom valid models of the difference between the registered images. This paper presents a non-rigid registration algorithm, which uses a model of bone growth as a model of the change...... between time sequence images of the human mandible. By being able to register the images, this paper at the same time contributes to the validation of the growth model, which is based on the currently available medical theories and knowledge...

  16. Investigation of the Process for Registration of Squoxin for Squawfish Control, Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    Rulifson, Robert L.

    1984-12-01

    Squawfish are a predator on downstream migrant salmon and steelhead. Squoxin, 1,1'-methylenedi-2-naphthol, is a specific toxin for squawfish. This report addresses the requirements and deficiencies in data necessary for squoxin registration as a pesticide. It includes an annotated bibliography, keyword index from published and unpublished sources covering information on squawfish, squoxin, state and federal regulations for pesticide registration. Squoxin is 100% lethal to squawfish at concentrations as low as 10 ppB for at least 2 hours. The recommended rate for field application is 100 ppB for 12 hours. At 100 ppB, the maximum LC/sub 0/ for the least squoxin tolerant salmonids is 7 to 17 times greater than the minimum LC/sub 100/ for northern squawfish. Squoxin is excreted in aquatic biota and mammals primarily via the bile. Squoxin shows little tendency to accumulate in animal tissues. A petition to register squoxin was submitted to EPA in 1977. EPA noted deficiencies in data including testing for residues in meat, milk, poultry, eggs, potable water, and irrigated crops; aquatic metabolism; mutagenicity; avian oral LC/sub 50/; acute LD/sub 50/ for freshwater invertebrates; freshwater fish LC/sub 50/; and acute LC/sub 50/ for marine organisms. Cost estimates for conducting the squoxin data research range from $436,600 to $2,070,000. Squawfish control with squoxin would represent an annual savings to the commercial and sports fishing industry of $20 to 25 million based on the value of the Columbia River salmon and steelhead lost to predation. The cost for registration of squoxin and initial treatment of the Columbia is far less than the value of returning adults from the smolts lost to predation in one year. 7 figs., 13 tabs.

  17. 77 FR 52368 - Manufacturer of Controlled Substances; Notice of Registration; Austin Pharma, LLC.

    Science.gov (United States)

    2012-08-29

    ...; Notice of Registration; Austin Pharma, LLC. By Notice dated May 9, 2012, and published in the Federal Register on May 21, 2012, 77 FR 30027, Austin Pharma LLC., 811 Paloma Drive, Suite C, Round Rock, Texas... factors in 21 U.S.C. 823(a) and determined that the registration of Austin Pharma LLC., to manufacture the...

  18. Registration of Vibro-acoustography Images and X-ray Mammography.

    Science.gov (United States)

    Gholam Hosseini, H; Fatemi, M; Alizad, A

    2005-01-01

    Image registration has been widely used for generating more diagnostic and clinical values in medical imaging. On the other hand, inaccurate image registration and incorrect localization of region of interest risks a potential impact on patients. Vibro-acoustography (VA) is a new imaging modality that has been applied to both medical and industrial imaging. Combining unique diagnostic information of VA with other medical imaging is one of our research interests. In this work, we studied the VA and x-ray image pairs and adopted a flexible control-point selection technique for image registration. A modified second-order polynomial, which leads to a scale/rotation/translation invariant registration, was used. The results of registration were used to spatially transform the breast VA images to map with the x-ray mammography with a registration error of less than 1.65 mm. These two completely different modalities were combined to generate an image including a ratio of each image pixel value. Therefore, the proposed technique allows clinicians to maximize their insight by combining the information from x-ray mammogram and VA modalities into a single image.

  19. 32 CFR 1615.1 - Registration.

    Science.gov (United States)

    2010-07-01

    ... registration card or other method of registration prescribed by the Director of Selective Service by a person... the records (master computer file) of the Selective Service System. Registration is completed when... Director include completing a Selective Service Registration Card at a classified Post Office, registration...

  20. Registration performance on EUV masks using high-resolution registration metrology

    Science.gov (United States)

    Steinert, Steffen; Solowan, Hans-Michael; Park, Jinback; Han, Hakseung; Beyer, Dirk; Scherübl, Thomas

    2016-10-01

    Next-generation lithography based on EUV continues to move forward to high-volume manufacturing. Given the technical challenges and the throughput concerns a hybrid approach with 193 nm immersion lithography is expected, at least in the initial state. Due to the increasing complexity at smaller nodes a multitude of different masks, both DUV (193 nm) and EUV (13.5 nm) reticles, will then be required in the lithography process-flow. The individual registration of each mask and the resulting overlay error are of crucial importance in order to ensure proper functionality of the chips. While registration and overlay metrology on DUV masks has been the standard for decades, this has yet to be demonstrated on EUV masks. Past generations of mask registration tools were not necessarily limited in their tool stability, but in their resolution capabilities. The scope of this work is an image placement investigation of high-end EUV masks together with a registration and resolution performance qualification. For this we employ a new generation registration metrology system embedded in a production environment for full-spec EUV masks. This paper presents excellent registration performance not only on standard overlay markers but also on more sophisticated e-beam calibration patterns.

  1. Endorsement of the CONSORT guidelines, trial registration, and the quality of reporting randomised controlled trials in leading nursing journals: A cross-sectional analysis.

    Science.gov (United States)

    Jull, Andrew; Aye, Phyu Sin

    2015-06-01

    To establish the reporting quality of trials published in leading nursing journals and investigate associations between CONSORT Statement or trial registration endorsment and reporting of design elements. The top 15 nursing journals were searched using Medline for randomised controlled trials published in 2012. Journals were categorised as CONSORT and trial registration promoting based on requirements of submitting authors or the journal's webpage as at January 2014. Data on sequence generation, allocation concealment, follow up, blinding, baseline equivalence and sample size calculation were extracted by one author and independently verified by the second author against source data. Seven journals were CONSORT promoting and three of these journals were also trial registration promoting. 114 citations were identified and 83 were randomised controlled trials. Eighteen trials (21.7%) were registered and those published in trial registration promoting journals were more likely to be registered (RR 2.64 95%CI 1.14-6.09). We assessed 68.7% of trials to be low risk of bias for sequence generation, 20.5% for allocation concealment, 38.6% for blinding, 55.4% for completeness of follow up and 79.5% for baseline equivalence. Trials published in CONSORT promoting journals were more likely to be at low risk of bias for blinding (RR 2.33, 95%CI 1.01-5.34) and completeness of follow up (RR 1.77, 95%CI 1.02-3.10), but journal endorsement of the CONSORT Statement or trial registration otherwise had no significant effect. Trials published in CONSORT and trial registration promoting journals were more likely to have high quality sample size calculations (RR 2.91, 95%CI 1.18-7.19 and RR 1.69, 95%CI 1.08-2.64, respectively). Simple endorsement of the CONSORT Statement and trials registration is insufficient action to encourage improvement of the quality of trial reporting across the most important of trial design elements. Copyright © 2014 Elsevier Ltd. All rights reserved.

  2. 78 FR 33441 - Importer of Controlled Substances; Notice of Registration; Caraco Pharmaceutical Laboratories, LTD

    Science.gov (United States)

    2013-06-04

    ... Registration; Caraco Pharmaceutical Laboratories, LTD By Notice dated February 8, 2013, and published in the Federal Register on February 21, 2013, 78 FR 12101, Caraco Pharmaceutical Laboratories, Ltd., 270 Prospect... 952(a), and determined that the registration of Caraco Pharmaceutical Laboratories, Ltd., to import...

  3. Information from the Registration Service

    CERN Multimedia

    GS Department

    2011-01-01

    Please note that the Registration Service (Bldg 55-1st floor) will be exceptionally open during the annual end of year closure from 10:00 to 12:00 on the following days: 22, 23, 26, 27,28, 29 et 30 December 2011 and 2,3, et 4 January 2012. All the activities related to the Registration Service will be operational: registration for contractors’ personnel; registrations for professional visits; access cards; car stickers; biometric registration. The Registration Service

  4. 77 FR 67397 - Importer Of Controlled Substances; Notice of Registration; Boehringer Ingelheim Chemicals, Inc.

    Science.gov (United States)

    2012-11-09

    ... Registration; Boehringer Ingelheim Chemicals, Inc. By Notice dated July 17, 2012, and published in the Federal Register on July 26, 2012, 77 FR 43861, Boehringer Ingelheim Chemicals, Inc., 2820 N. Normandy Drive...), and determined that the registration of Boehringer Ingelheim Chemicals, Inc., to import the basic...

  5. 77 FR 47114 - Manufacturer of Controlled Substances; Notice of Registration; Catalent Pharma Solutions, Inc.

    Science.gov (United States)

    2012-08-07

    ...; Notice of Registration; Catalent Pharma Solutions, Inc. By Notice dated April 17, 2012, and published in the Federal Register on April 26, 2012, 77 FR 24984, Catalent Pharma Solutions, Inc., 10381 Decatur...) and 952(a) and determined that the registration of Catalent Pharma Solutions, Inc. to import the basic...

  6. 78 FR 64018 - Manufacturer of Controlled Substances; Notice of Registration; Boehringer Ingelheim Chemicals, Inc.

    Science.gov (United States)

    2013-10-25

    ...; Notice of Registration; Boehringer Ingelheim Chemicals, Inc. By Notice dated June 18, 2013, and published in the Federal Register on July 1, 2013, 78 FR 39340, Boehringer Ingelheim Chemicals, Inc., 2820 N... 21 U.S.C. 823(a) and determined that the registration of Boehringer Ingelheim Chemicals, Inc., to...

  7. Automated landmark-guided deformable image registration.

    Science.gov (United States)

    Kearney, Vasant; Chen, Susie; Gu, Xuejun; Chiu, Tsuicheng; Liu, Honghuan; Jiang, Lan; Wang, Jing; Yordy, John; Nedzi, Lucien; Mao, Weihua

    2015-01-07

    The purpose of this work is to develop an automated landmark-guided deformable image registration (LDIR) algorithm between the planning CT and daily cone-beam CT (CBCT) with low image quality. This method uses an automated landmark generation algorithm in conjunction with a local small volume gradient matching search engine to map corresponding landmarks between the CBCT and the planning CT. The landmarks act as stabilizing control points in the following Demons deformable image registration. LDIR is implemented on graphics processing units (GPUs) for parallel computation to achieve ultra fast calculation. The accuracy of the LDIR algorithm has been evaluated on a synthetic case in the presence of different noise levels and data of six head and neck cancer patients. The results indicate that LDIR performed better than rigid registration, Demons, and intensity corrected Demons for all similarity metrics used. In conclusion, LDIR achieves high accuracy in the presence of multimodality intensity mismatch and CBCT noise contamination, while simultaneously preserving high computational efficiency.

  8. Automated landmark-guided deformable image registration

    International Nuclear Information System (INIS)

    Kearney, Vasant; Chen, Susie; Gu, Xuejun; Chiu, Tsuicheng; Liu, Honghuan; Jiang, Lan; Wang, Jing; Yordy, John; Nedzi, Lucien; Mao, Weihua

    2015-01-01

    The purpose of this work is to develop an automated landmark-guided deformable image registration (LDIR) algorithm between the planning CT and daily cone-beam CT (CBCT) with low image quality. This method uses an automated landmark generation algorithm in conjunction with a local small volume gradient matching search engine to map corresponding landmarks between the CBCT and the planning CT. The landmarks act as stabilizing control points in the following Demons deformable image registration. LDIR is implemented on graphics processing units (GPUs) for parallel computation to achieve ultra fast calculation. The accuracy of the LDIR algorithm has been evaluated on a synthetic case in the presence of different noise levels and data of six head and neck cancer patients. The results indicate that LDIR performed better than rigid registration, Demons, and intensity corrected Demons for all similarity metrics used. In conclusion, LDIR achieves high accuracy in the presence of multimodality intensity mismatch and CBCT noise contamination, while simultaneously preserving high computational efficiency. (paper)

  9. Quality Assurance of Serial 3D Image Registration, Fusion, and Segmentation

    International Nuclear Information System (INIS)

    Sharpe, Michael; Brock, Kristy K.

    2008-01-01

    Radiotherapy relies on images to plan, guide, and assess treatment. Image registration, fusion, and segmentation are integral to these processes; specifically for aiding anatomic delineation, assessing organ motion, and aligning targets with treatment beams in image-guided radiation therapy (IGRT). Future developments in image registration will also improve estimations of the actual dose delivered and quantitative assessment in patient follow-up exams. This article summarizes common and emerging technologies and reviews the role of image registration, fusion, and segmentation in radiotherapy processes. The current quality assurance practices are summarized, and implications for clinical procedures are discussed

  10. 75 FR 43166 - Information Collection; OMB Control No. 3090-00XX; FSRS Registration and Prime Awardee Entity...

    Science.gov (United States)

    2010-07-23

    ... ``Information Collection 3090-XXXX, FSRS Registration and Prime Awardee Entity- Related Information [[Page 43167... ``Submit a Comment'' that corresponds with ``Information Collection 3090-XXXX, FSRS Registration and Prime... 3090-XXXX, FSRS Registration and Prime Awardee Entity- Related Information Reporting Requirements'' on...

  11. 77 FR 24988 - Manufacturer of Controlled Substances; Notice of Registration; Johnson Matthey Pharma Services

    Science.gov (United States)

    2012-04-26

    ...; Notice of Registration; Johnson Matthey Pharma Services By Notice dated December 5, 2011, and published in the Federal Register on December 12, 2011, 76 FR 77257, Johnson Matthey Pharma Services, 70... factors in 21 U.S.C. 823(a) and determined that the registration of Johnson Matthey Pharma Services to...

  12. 77 FR 70188 - Manufacturer of Controlled Substances; Notice of Registration; Boehringer Ingelheim Chemicals, Inc.

    Science.gov (United States)

    2012-11-23

    ...; Notice of Registration; Boehringer Ingelheim Chemicals, Inc. By Notice dated July 17, 2012, and published in the Federal Register on July 26, 2012, 77 FR 43863, Boehringer Ingelheim Chemicals, Inc., 2820 N... has considered the factors in 21 U.S.C. 823(a) and determined that the registration of Boehringer...

  13. 75 FR 76756 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2010-12-09

    ... Johnson Matthey Pharmaceutical Materials, Inc. to ensure that the company's registration is consistent..., 2010, (75 FR 44285), Johnson Matthey Pharmaceutical Materials, Inc., Pharmaceuticals Service, 25 Patton... (9740) II Remifentanil (9739) II Hydrocodone (9193) II The company plans to utilize this facility to...

  14. Analysis of the utilization of existing test data for phase-in substance registration under the Act on the Registration and Evaluation, etc. of Chemical Substances.

    Science.gov (United States)

    Choi, Bong-In; Kwak, Yeong-Don; Jung, Yu-Mi; Ryu, Byung-Taek; Kim, Chang Gyun

    2015-01-01

    Approximately 2000 phase-in substances are subject to registration according to the Act on the Registration and Evaluation, etc. of Chemical Substances (KREACH), and the expected testing cost is 2.06 trillion Korean won assuming all the test data required for registration are acquired. The extent to which these enormous test costs can be reduced depends on the availability of existing data that can be used to meet the requirements of the K-REACH we examined the current availability of test data that can be used for chemical substance registration. We analyzed the possibility of utilizing the existing test data obtained from 16 reference databases for 369 of 518 kinds of phase-in substances subject to registration that were reported in last October 2014. The physical and chemical properties were available for 57.1% of substances, whereas data regarding human hazards and environmental hazards were available at considerably lower rates, 8.5% and 11.8%, respectively. Physical and chemical properties were available for a fairly high proportion, whereas human hazards and environmental hazards were reported for considerably fewer substances.

  15. Assessment of rigid multi-modality image registration consistency using the multiple sub-volume registration (MSR) method

    International Nuclear Information System (INIS)

    Ceylan, C; Heide, U A van der; Bol, G H; Lagendijk, J J W; Kotte, A N T J

    2005-01-01

    Registration of different imaging modalities such as CT, MRI, functional MRI (fMRI), positron (PET) and single photon (SPECT) emission tomography is used in many clinical applications. Determining the quality of any automatic registration procedure has been a challenging part because no gold standard is available to evaluate the registration. In this note we present a method, called the 'multiple sub-volume registration' (MSR) method, for assessing the consistency of a rigid registration. This is done by registering sub-images of one data set on the other data set, performing a crude non-rigid registration. By analysing the deviations (local deformations) of the sub-volume registrations from the full registration we get a measure of the consistency of the rigid registration. Registration of 15 data sets which include CT, MR and PET images for brain, head and neck, cervix, prostate and lung was performed utilizing a rigid body registration with normalized mutual information as the similarity measure. The resulting registrations were classified as good or bad by visual inspection. The resulting registrations were also classified using our MSR method. The results of our MSR method agree with the classification obtained from visual inspection for all cases (p < 0.02 based on ANOVA of the good and bad groups). The proposed method is independent of the registration algorithm and similarity measure. It can be used for multi-modality image data sets and different anatomic sites of the patient. (note)

  16. 21 CFR 1301.52 - Termination of registration; transfer of registration; distribution upon discontinuance of business.

    Science.gov (United States)

    2010-04-01

    ... discontinues business or professional practice. Any registrant who ceases legal existence or discontinues... registration; distribution upon discontinuance of business. 1301.52 Section 1301.52 Food and Drugs DRUG... of registration; transfer of registration; distribution upon discontinuance of business. (a) Except...

  17. Reforming birth registration law in England and Wales?

    Directory of Open Access Journals (Sweden)

    Julie McCandless

    2017-06-01

    Full Text Available The Law Commission of England and Wales is considering what its 13th Programme of Law Reform should address. During the consultation process, a project on birth registration law has been mooted. This is a very welcome proposal given that civil birth registration in England and Wales is a compulsory procedure that not only finds its roots in the early Victorian era, but also remains very similar, at least in terms of form and the information that is recorded. I first use two recent legal challenges to illustrate why the current system is coming under increasing pressure. I further use these examples to caution against a law reform agenda that is narrowly focused on the precise information recorded, without a preliminary and wider examination of what the role and purpose of birth registration is, and should be, in society. I argue that this needs to be addressed before the state can justify the parameters of the information recorded. I then use an outline of historical reforms relating to the registration of births outside of marriage to highlight the normative two-parent family model that underpins the birth registration system. I argue that legal reform must be cognizant of the tenacity of this normative family model, particularly in relation to reform proposals surrounding donor conception and the annotation of birth certificates. Finally, I draw attention to wider developments in family law that cast birth registration as a social policy tool for the facilitation of parent–child relationships, particularly unmarried fathers.

  18. 78 FR 23958 - Manufacturer of Controlled Substances; Notice of Registration; S & B Pharma Inc.

    Science.gov (United States)

    2013-04-23

    ...; Notice of Registration; S & B Pharma Inc. By Notice dated May 31, 2012, and published in the Federal Register on June 8, 2012, 77 FR 34073, S & B Pharma Inc., 405 South Motor Avenue, Azusa, California 91702... 21 U.S.C. 823(a), and determined that the registration of S & B Pharma Inc., to manufacture the...

  19. Personal protective equipment for registration purposes of pesticides

    NARCIS (Netherlands)

    Gerritsen-Ebben, M.G.; Brouwer, D.H.; Hemmen, J.J. van

    2007-01-01

    Regulatory authorities in North America, Europe and Australia use different approaches for the estimation of exposure reduction effectiveness of personal protective equipment (PPE) in registration processes of agrochemical pesticides. TNO has investigated current views and facts for the use of

  20. Pydpiper: A Flexible Toolkit for Constructing Novel Registration Pipelines

    Directory of Open Access Journals (Sweden)

    Miriam eFriedel

    2014-07-01

    Full Text Available Using neuroimaging technologies to elucidate the relationship between genotype and phenotype and brain and behavior will be a key contribution to biomedical research in the twenty-first century. Among the many methods for analyzing neuroimaging data, image registration deserves particular attention due to its wide range of applications. Finding strategies to register together many images and analyze the differences between them can be a challenge, particularly given that different experimental designs require different registration strategies. Moreover, writing software that can handle different types of image registration pipelines in a flexible, reusable and extensible way can be challenging. In response to this challenge, we have created Pydpiper, a neuroimaging registration toolkit written in Python. Pydpiper is an open-source, freely available pipeline framework that provides multiple modules for various image registration applications. Pydpiper offers five key innovations. Specifically: (1 a robust file handling class that allows access to outputs from all stages of registration at any point in the pipeline; (2 the ability of the framework to eliminate duplicate stages; (3 reusable, easy to subclass modules; (4 a development toolkit written for non-developers; (5 four complete applications that run complex image registration pipelines ``out-of-the-box.'' In this paper, we will discuss both the general Pydpiper framework and the various ways in which component modules can be pieced together to easily create new registration pipelines. This will include a discussion of the core principles motivating code development and a comparison of Pydpiper with other available toolkits. We also provide a comprehensive, line-by-line example to orient users with limited programming knowledge and highlight some of the most useful features of Pydpiper. In addition, we will present the four current applications of the code.

  1. Pydpiper: a flexible toolkit for constructing novel registration pipelines.

    Science.gov (United States)

    Friedel, Miriam; van Eede, Matthijs C; Pipitone, Jon; Chakravarty, M Mallar; Lerch, Jason P

    2014-01-01

    Using neuroimaging technologies to elucidate the relationship between genotype and phenotype and brain and behavior will be a key contribution to biomedical research in the twenty-first century. Among the many methods for analyzing neuroimaging data, image registration deserves particular attention due to its wide range of applications. Finding strategies to register together many images and analyze the differences between them can be a challenge, particularly given that different experimental designs require different registration strategies. Moreover, writing software that can handle different types of image registration pipelines in a flexible, reusable and extensible way can be challenging. In response to this challenge, we have created Pydpiper, a neuroimaging registration toolkit written in Python. Pydpiper is an open-source, freely available software package that provides multiple modules for various image registration applications. Pydpiper offers five key innovations. Specifically: (1) a robust file handling class that allows access to outputs from all stages of registration at any point in the pipeline; (2) the ability of the framework to eliminate duplicate stages; (3) reusable, easy to subclass modules; (4) a development toolkit written for non-developers; (5) four complete applications that run complex image registration pipelines "out-of-the-box." In this paper, we will discuss both the general Pydpiper framework and the various ways in which component modules can be pieced together to easily create new registration pipelines. This will include a discussion of the core principles motivating code development and a comparison of Pydpiper with other available toolkits. We also provide a comprehensive, line-by-line example to orient users with limited programming knowledge and highlight some of the most useful features of Pydpiper. In addition, we will present the four current applications of the code.

  2. 75 FR 75498 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2010-12-03

    ..., (75 FR 32506), Boehringer Ingelheim Chemicals, Inc., 2820 N. Normandy Drive, Petersburg, Virginia... has considered the factors in 21 U.S.C. 823(a) and determined that the registration of Boehringer... with the public interest at this time. DEA has investigated Boehringer Ingelheim Chemicals, Inc. to...

  3. Performance evaluation of 2D image registration algorithms with the numeric image registration and comparison platform

    International Nuclear Information System (INIS)

    Gerganov, G.; Kuvandjiev, V.; Dimitrova, I.; Mitev, K.; Kawrakow, I.

    2012-01-01

    The objective of this work is to present the capabilities of the NUMERICS web platform for evaluation of the performance of image registration algorithms. The NUMERICS platform is a web accessible tool which provides access to dedicated numerical algorithms for registration and comparison of medical images (http://numerics.phys.uni-sofia.bg). The platform allows comparison of noisy medical images by means of different types of image comparison algorithms, which are based on statistical tests for outliers. The platform also allows 2D image registration with different techniques like Elastic Thin-Plate Spline registration, registration based on rigid transformations, affine transformations, as well as non-rigid image registration based on Mobius transformations. In this work we demonstrate how the platform can be used as a tool for evaluation of the quality of the image registration process. We demonstrate performance evaluation of a deformable image registration technique based on Mobius transformations. The transformations are applied with appropriate cost functions like: Mutual information, Correlation coefficient, Sum of Squared Differences. The accent is on the results provided by the platform to the user and their interpretation in the context of the performance evaluation of 2D image registration. The NUMERICS image registration and image comparison platform provides detailed statistical information about submitted image registration jobs and can be used to perform quantitative evaluation of the performance of different image registration techniques. (authors)

  4. Evaluation of body-wise and organ-wise registrations for abdominal organs

    Science.gov (United States)

    Xu, Zhoubing; Panjwani, Sahil A.; Lee, Christopher P.; Burke, Ryan P.; Baucom, Rebeccah B.; Poulose, Benjamin K.; Abramson, Richard G.; Landman, Bennett A.

    2016-03-01

    Identifying cross-sectional and longitudinal correspondence in the abdomen on computed tomography (CT) scans is necessary for quantitatively tracking change and understanding population characteristics, yet abdominal image registration is a challenging problem. The key difficulty in solving this problem is huge variations in organ dimensions and shapes across subjects. The current standard registration method uses the global or body-wise registration technique, which is based on the global topology for alignment. This method (although producing decent results) has substantial influence of outliers, thus leaving room for significant improvement. Here, we study a new image registration approach using local (organ-wise registration) by first creating organ-specific bounding boxes and then using these regions of interest (ROIs) for aligning references to target. Based on Dice Similarity Coefficient (DSC), Mean Surface Distance (MSD) and Hausdorff Distance (HD), the organ-wise approach is demonstrated to have significantly better results by minimizing the distorting effects of organ variations. This paper compares exclusively the two registration methods by providing novel quantitative and qualitative comparison data and is a subset of the more comprehensive problem of improving the multi-atlas segmentation by using organ normalization.

  5. Hierarchical and successive approximate registration of the non-rigid medical image based on thin-plate splines

    Science.gov (United States)

    Hu, Jinyan; Li, Li; Yang, Yunfeng

    2017-06-01

    The hierarchical and successive approximate registration method of non-rigid medical image based on the thin-plate splines is proposed in the paper. There are two major novelties in the proposed method. First, the hierarchical registration based on Wavelet transform is used. The approximate image of Wavelet transform is selected as the registered object. Second, the successive approximation registration method is used to accomplish the non-rigid medical images registration, i.e. the local regions of the couple images are registered roughly based on the thin-plate splines, then, the current rough registration result is selected as the object to be registered in the following registration procedure. Experiments show that the proposed method is effective in the registration process of the non-rigid medical images.

  6. Designing single phase Current-Programmed-Controlled rectifiers by harmonic currents

    DEFF Research Database (Denmark)

    Andersen, Gert Karmisholt; Blaabjerg, Frede

    2002-01-01

    The grid current harmonics of a Current-Programmed-Controlled (CPC) pfc rectifier strongly depends on the choice of switching frequency and switching inductance. This paper describes a new simple and vert fast method to calculate the grid current of a CPC controlled pfc converter. The method...

  7. X-ray tube current control

    International Nuclear Information System (INIS)

    Dupuis, W.A.; Resnick, T.A.

    1982-01-01

    A closed loop feedback system for controlling the current output of an x-ray tube. The system has circuitry for improving the transient response and stability of the x-ray tube current over a substantial nonlinear portion of the tube current production characteristic. The system includes a reference generator for applying adjustable step function reference signals representing desired tube currents. The system also includes means for instantaneous sensing of actual tube current. An error detector compares the value of actual and reference tube current and produces an error signal as a function of their difference. The system feedback loop includes amplification circuitry for controlling x-ray tube filament dc voltage to regulate tube current as a function of the error signal value. The system also includes compensation circuitry, between the reference generator and the amplification circuitry, to vary the loop gain of the feedback control system as a function of the reference magnitude

  8. Image registration with uncertainty analysis

    Science.gov (United States)

    Simonson, Katherine M [Cedar Crest, NM

    2011-03-22

    In an image registration method, edges are detected in a first image and a second image. A percentage of edge pixels in a subset of the second image that are also edges in the first image shifted by a translation is calculated. A best registration point is calculated based on a maximum percentage of edges matched. In a predefined search region, all registration points other than the best registration point are identified that are not significantly worse than the best registration point according to a predetermined statistical criterion.

  9. 77 FR 5849 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2012-02-06

    ... company plans to manufacture a radioactive product to diagnose Parkinson's disease, and to manufacture a... physical security systems, verification of the company's compliance with state and local laws, and a review.... DEA has considered the factors in 21 U.S.C. 823(a) and determined that the registration of GE...

  10. A Remote Registration Based on MIDAS

    Science.gov (United States)

    JIN, Xin

    2017-04-01

    We often need for software registration to protect the interests of the software developers. This article narrated one kind of software long-distance registration technology. The registration method is: place the registration information in a database table, after the procedure starts in check table registration information, if it has registered then the procedure may the normal operation; Otherwise, the customer must input the sequence number and registers through the network on the long-distance server. If it registers successfully, then records the registration information in the database table. This remote registration method can protect the rights of software developers.

  11. Robust surface registration using salient anatomical features for image-guided liver surgery: Algorithm and validation

    OpenAIRE

    Clements, Logan W.; Chapman, William C.; Dawant, Benoit M.; Galloway, Robert L.; Miga, Michael I.

    2008-01-01

    A successful surface-based image-to-physical space registration in image-guided liver surgery (IGLS) is critical to provide reliable guidance information to surgeons and pertinent surface displacement data for use in deformation correction algorithms. The current protocol used to perform the image-to-physical space registration involves an initial pose estimation provided by a point based registration of anatomical landmarks identifiable in both the preoperative tomograms and the intraoperati...

  12. 76 FR 8777 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2011-02-15

    ... radioactive product used in diagnostic imaging in the diagnosis of Parkinson's Disease and for manufacture in... laws, and a review of the company's background and history. Therefore, pursuant to 21 U.S.C. 823(a... been received. DEA has considered the factors in 21 U.S.C. 823(a) and determined that the registration...

  13. Increasing the automation of a 2D-3D registration system.

    Science.gov (United States)

    Varnavas, Andreas; Carrell, Tom; Penney, Graeme

    2013-02-01

    Routine clinical use of 2D-3D registration algorithms for Image Guided Surgery remains limited. A key aspect for routine clinical use of this technology is its degree of automation, i.e., the amount of necessary knowledgeable interaction between the clinicians and the registration system. Current image-based registration approaches usually require knowledgeable manual interaction during two stages: for initial pose estimation and for verification of produced results. We propose four novel techniques, particularly suited to vertebra-based registration systems, which can significantly automate both of the above stages. Two of these techniques are based upon the intraoperative "insertion" of a virtual fiducial marker into the preoperative data. The remaining two techniques use the final registration similarity value between multiple CT vertebrae and a single fluoroscopy vertebra. The proposed methods were evaluated with data from 31 operations (31 CT scans, 419 fluoroscopy images). Results show these methods can remove the need for manual vertebra identification during initial pose estimation, and were also very effective for result verification, producing a combined true positive rate of 100% and false positive rate equal to zero. This large decrease in required knowledgeable interaction is an important contribution aiming to enable more widespread use of 2D-3D registration technology.

  14. Transparency of Outcome Reporting and Trial Registration of Randomized Controlled Trials Published in the Journal of Consulting and Clinical Psychology.

    Science.gov (United States)

    Azar, Marleine; Riehm, Kira E; McKay, Dean; Thombs, Brett D

    2015-01-01

    Confidence that randomized controlled trial (RCT) results accurately reflect intervention effectiveness depends on proper trial conduct and the accuracy and completeness of published trial reports. The Journal of Consulting and Clinical Psychology (JCCP) is the primary trials journal amongst American Psychological Association (APA) journals. The objectives of this study were to review RCTs recently published in JCCP to evaluate (1) adequacy of primary outcome analysis definitions; (2) registration status; and, (3) among registered trials, adequacy of outcome registrations. Additionally, we compared results from JCCP to findings from a recent study of top psychosomatic and behavioral medicine journals. Eligible RCTs were published in JCCP in 2013-2014. For each RCT, two investigators independently extracted data on (1) adequacy of outcome analysis definitions in the published report, (2) whether the RCT was registered prior to enrolling patients, and (3) adequacy of outcome registration. Of 70 RCTs reviewed, 12 (17.1%) adequately defined primary or secondary outcome analyses, whereas 58 (82.3%) had multiple primary outcome analyses without statistical adjustment or undefined outcome analyses. There were 39 (55.7%) registered trials. Only two trials registered prior to patient enrollment with a single primary outcome variable and time point of assessment. However, in one of the two trials, registered and published outcomes were discrepant. No studies were adequately registered as per Standard Protocol Items: Recommendation for Interventional Trials guidelines. Compared to psychosomatic and behavioral medicine journals, the proportion of published trials with adequate outcome analysis declarations was significantly lower in JCCP (17.1% versus 32.9%; p = 0.029). The proportion of registered trials in JCCP (55.7%) was comparable to behavioral medicine journals (52.6%; p = 0.709). The quality of published outcome analysis definitions and trial registrations in JCCP is

  15. Transparency of Outcome Reporting and Trial Registration of Randomized Controlled Trials Published in the Journal of Consulting and Clinical Psychology.

    Directory of Open Access Journals (Sweden)

    Marleine Azar

    Full Text Available Confidence that randomized controlled trial (RCT results accurately reflect intervention effectiveness depends on proper trial conduct and the accuracy and completeness of published trial reports. The Journal of Consulting and Clinical Psychology (JCCP is the primary trials journal amongst American Psychological Association (APA journals. The objectives of this study were to review RCTs recently published in JCCP to evaluate (1 adequacy of primary outcome analysis definitions; (2 registration status; and, (3 among registered trials, adequacy of outcome registrations. Additionally, we compared results from JCCP to findings from a recent study of top psychosomatic and behavioral medicine journals.Eligible RCTs were published in JCCP in 2013-2014. For each RCT, two investigators independently extracted data on (1 adequacy of outcome analysis definitions in the published report, (2 whether the RCT was registered prior to enrolling patients, and (3 adequacy of outcome registration.Of 70 RCTs reviewed, 12 (17.1% adequately defined primary or secondary outcome analyses, whereas 58 (82.3% had multiple primary outcome analyses without statistical adjustment or undefined outcome analyses. There were 39 (55.7% registered trials. Only two trials registered prior to patient enrollment with a single primary outcome variable and time point of assessment. However, in one of the two trials, registered and published outcomes were discrepant. No studies were adequately registered as per Standard Protocol Items: Recommendation for Interventional Trials guidelines. Compared to psychosomatic and behavioral medicine journals, the proportion of published trials with adequate outcome analysis declarations was significantly lower in JCCP (17.1% versus 32.9%; p = 0.029. The proportion of registered trials in JCCP (55.7% was comparable to behavioral medicine journals (52.6%; p = 0.709.The quality of published outcome analysis definitions and trial registrations in JCCP is

  16. Unified voxel- and tensor-based morphometry (UVTBM) using registration confidence.

    Science.gov (United States)

    Khan, Ali R; Wang, Lei; Beg, Mirza Faisal

    2015-01-01

    Voxel-based morphometry (VBM) and tensor-based morphometry (TBM) both rely on spatial normalization to a template and yet have different requirements for the level of registration accuracy. VBM requires only global alignment of brain structures, with limited degrees of freedom in transformation, whereas TBM performs best when the registration is highly deformable and can achieve higher registration accuracy. In addition, the registration accuracy varies over the whole brain, with higher accuracy typically observed in subcortical areas and lower accuracy seen in cortical areas. Hence, even the determinant of Jacobian of registration maps is spatially varying in their accuracy, and combining these with VBM by direct multiplication introduces errors in VBM maps where the registration is inaccurate. We propose a unified approach to combining these 2 morphometry methods that is motivated by these differing requirements for registration and our interest in harnessing the advantages of both. Our novel method uses local estimates of registration confidence to determine how to weight the influence of VBM- and TBM-like approaches. Results are shown on healthy and mild Alzheimer's subjects (N = 150) investigating age and group differences, and potential of differential diagnosis is shown on a set of Alzheimer's disease (N = 34) and frontotemporal dementia (N = 30) patients compared against controls (N = 14). These show that the group differences detected by our proposed approach are more descriptive than those detected from VBM, Jacobian-modulated VBM, and TBM separately, hence leveraging the advantages of both approaches in a unified framework. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. [Non-rigid medical image registration based on mutual information and thin-plate spline].

    Science.gov (United States)

    Cao, Guo-gang; Luo, Li-min

    2009-01-01

    To get precise and complete details, the contrast in different images is needed in medical diagnosis and computer assisted treatment. The image registration is the basis of contrast, but the regular rigid registration does not satisfy the clinic requirements. A non-rigid medical image registration method based on mutual information and thin-plate spline was present. Firstly, registering two images globally based on mutual information; secondly, dividing reference image and global-registered image into blocks and registering them; then getting the thin-plate spline transformation according to the shift of blocks' center; finally, applying the transformation to the global-registered image. The results show that the method is more precise than the global rigid registration based on mutual information and it reduces the complexity of getting control points and satisfy the clinic requirements better by getting control points of the thin-plate transformation automatically.

  18. 12 CFR 584.1 - Registration, examination and reports.

    Science.gov (United States)

    2010-01-01

    ... Section 584.1 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SAVINGS AND LOAN... loan holding company, each savings and loan holding company shall register with the OTS by filing a registration statement H-(b)10. (2) Filing of annual/current reports. Each registered savings and loan holding...

  19. The hidden KPI registration accuracy.

    Science.gov (United States)

    Shorrosh, Paul

    2011-09-01

    Determining the registration accuracy rate is fundamental to improving revenue cycle key performance indicators. A registration quality assurance (QA) process allows errors to be corrected before bills are sent and helps registrars learn from their mistakes. Tools are available to help patient access staff who perform registration QA manually.

  20. Current control of PMSM based on maximum torque control reference frame

    Science.gov (United States)

    Ohnuma, Takumi

    2017-07-01

    This study presents a new method of current controls of PMSMs (Permanent Magnet Synchronous Motors) based on a maximum torque control reference frame, which is suitable for high-performance controls of the PMSMs. As the issues of environment and energy increase seriously, PMSMs, one of the AC motors, are becoming popular because of their high-efficiency and high-torque density in various applications, such as electric vehicles, trains, industrial machines, and home appliances. To use the PMSMs efficiently, a proper current control of the PMSMs is necessary. In general, a rotational coordinate system synchronizing with the rotor is used for the current control of PMSMs. In the rotating reference frame, the current control is easier because the currents on the rotating reference frame can be expressed as a direct current in the controller. On the other hand, the torque characteristics of PMSMs are non-linear and complex; the PMSMs are efficient and high-density though. Therefore, a complicated control system is required to involve the relation between the torque and the current, even though the rotating reference frame is adopted. The maximum torque control reference frame provides a simpler way to control efficiently the currents taking the torque characteristics of the PMSMs into consideration.

  1. 12 CFR 583.18 - Registrant.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Registrant. 583.18 Section 583.18 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY DEFINITIONS FOR REGULATIONS AFFECTING SAVINGS AND LOAN HOLDING COMPANIES § 583.18 Registrant. The term registrant means a savings and loan...

  2. Proportional-Integral-Resonant AC Current Controller

    Directory of Open Access Journals (Sweden)

    STOJIC, D.

    2017-02-01

    Full Text Available In this paper an improved stationary-frame AC current controller based on the proportional-integral-resonant control action (PIR is proposed. Namely, the novel two-parameter PIR controller is applied in the stationary-frame AC current control, accompanied by the corresponding parameter-tuning procedure. In this way, the proportional-resonant (PR controller, common in the stationary-frame AC current control, is extended by the integral (I action in order to enable the AC current DC component tracking, and, also, to enable the DC disturbance compensation, caused by the voltage source inverter (VSI nonidealities and by nonlinear loads. The proposed controller parameter-tuning procedure is based on the three-phase back-EMF-type load, which corresponds to a wide range of AC power converter applications, such as AC motor drives, uninterruptible power supplies, and active filters. While the PIR controllers commonly have three parameters, the novel controller has two. Also, the provided parameter-tuning procedure needs only one parameter to be tuned in relation to the load and power converter model parameters, since the second controller parameter is directly derived from the required controller bandwidth value. The dynamic performance of the proposed controller is verified by means of simulation and experimental runs.

  3. 77 FR 66920 - Registration of Claims to Copyright: Group Registration of Serial Issues Filed Electronically

    Science.gov (United States)

    2012-11-08

    ... registered on a single application and for a single fee. The group registration privilege is contingent upon... was limited to basic registrations, i.e., claims in single works, while the capacity to process online... of related serials. Revisions to the electronic registration system will upgrade the capacity of the...

  4. 78 FR 3646 - Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for...

    Science.gov (United States)

    2013-01-16

    ... proposing to revise certain definitions in FDA's current regulation for Registration of Food Facilities to.... Proposed Revisions for Consistency With the Definition of ``Food'' F. Proposed Revisions To Address... globalization, which has resulted in approximately 15 percent of the U.S. food supply being imported, including...

  5. INVITED REVIEW--IMAGE REGISTRATION IN VETERINARY RADIATION ONCOLOGY: INDICATIONS, IMPLICATIONS, AND FUTURE ADVANCES.

    Science.gov (United States)

    Feng, Yang; Lawrence, Jessica; Cheng, Kun; Montgomery, Dean; Forrest, Lisa; Mclaren, Duncan B; McLaughlin, Stephen; Argyle, David J; Nailon, William H

    2016-01-01

    The field of veterinary radiation therapy (RT) has gained substantial momentum in recent decades with significant advances in conformal treatment planning, image-guided radiation therapy (IGRT), and intensity-modulated (IMRT) techniques. At the root of these advancements lie improvements in tumor imaging, image alignment (registration), target volume delineation, and identification of critical structures. Image registration has been widely used to combine information from multimodality images such as computerized tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET) to improve the accuracy of radiation delivery and reliably identify tumor-bearing areas. Many different techniques have been applied in image registration. This review provides an overview of medical image registration in RT and its applications in veterinary oncology. A summary of the most commonly used approaches in human and veterinary medicine is presented along with their current use in IGRT and adaptive radiation therapy (ART). It is important to realize that registration does not guarantee that target volumes, such as the gross tumor volume (GTV), are correctly identified on the image being registered, as limitations unique to registration algorithms exist. Research involving novel registration frameworks for automatic segmentation of tumor volumes is ongoing and comparative oncology programs offer a unique opportunity to test the efficacy of proposed algorithms. © 2016 American College of Veterinary Radiology.

  6. A first step toward uncovering the truth about weight tuning in deformable image registration

    Science.gov (United States)

    Pirpinia, Kleopatra; Bosman, Peter A. N.; Sonke, Jan-Jakob; van Herk, Marcel; Alderliesten, Tanja

    2016-03-01

    Deformable image registration is currently predominantly solved by optimizing a weighted linear combination of objectives. Successfully tuning the weights associated with these objectives is not trivial, leading to trial-and-error approaches. Such an approach assumes an intuitive interplay between weights, optimization objectives, and target registration errors. However, it is not known whether this always holds for existing registration methods. To investigate the interplay between weights, optimization objectives, and registration errors, we employ multi-objective optimization. Here, objectives of interest are optimized simultaneously, causing a set of multiple optimal solutions to exist, called the optimal Pareto front. Our medical application is in breast cancer and includes the challenging prone-supine registration problem. In total, we studied the interplay in three different ways. First, we ran many random linear combinations of objectives using the well-known registration software elastix. Second, since the optimization algorithms used in registration are typically of a local-search nature, final solutions may not always form a Pareto front. We therefore employed a multi-objective evolutionary algorithm that finds weights that correspond to registration outcomes that do form a Pareto front. Third, we examined how the interplay differs if a true multi-objective (i.e., weight-free) image registration method is used. Results indicate that a trial-and-error weight-adaptation approach can be successful for the easy prone to prone breast image registration case, due to the absence of many local optima. With increasing problem difficulty the use of more advanced approaches can be of value in finding and selecting the optimal registration outcomes.

  7. Automatic registration using implicit shape representations: applications in intraoperative 3D rotational angiography to preoperative CTA registration

    International Nuclear Information System (INIS)

    Subramanian, Navneeth; Pichon, Eric; Solomon, Stephen B.

    2009-01-01

    A solution for automatic registration of 3D rotational angiography (XA) to CT/MR of the liver. Targeted for use in treatment planning of liver interventions. A shape-based approach to registration is proposed that does not require specification of landmarks nor is it prone to local minima like purely intensity-based registration methods. Through the use of vessel characteristics, accurate registration is possible even in the presence of deformations induced by catheters and respiratory motion. Registration was performed on eight pairs of multiphase CT angiography and 3D rotational digital angiography datasets. Quantitative validation of the registration accuracy using vessel landmarks was performed on these datasets. The validation study showed that the method has a registration error of 9.41±4.13 mm. In addition, the computation time is well below 60 s making it attractive for clinical application. A new method for fully automatic 3DXA to CT/MR image registration was developed and found to be efficient and accurate using clinically realistic datasets. (orig.)

  8. Registration for the Hanford Site: Sources of radioactive emissions

    International Nuclear Information System (INIS)

    Silvia, M.J.

    1993-04-01

    This Registration Application serves to renew the registration for all Hanford Site sources of radioactive air emissions routinely reported to the State of Washington Department of Health (DOH). The current registration expires on August 15, 1993. The Application is submitted pursuant to the Washington Administrative Code (WAC) Chapter 246--247, and is consistent with guidance provided by DOH for renewal. The Application subdivides the Hanford Site into six major production, processing or research areas. Those six areas are in the 100 Area, 200 East Area, 200 West Area, 300 Area, 400 Area, and 600 Area. Each major group of point sources within the six areas listed above is represented by a Source Registration for Radioactive Air Emissions form. Annual emissions. for the sources are listed in the ''Radionuclide Air Emissions Report for the Hanford Site,'' published annually. It is a requirement that the following Statement of Compliance be provided: ''The radioactive air emissions from the above sources do meet the emissions standards contained in Chapter 173-480-040 WAC, Ambient Air Quality Standards and Emissions Limits for Radionuclides. As the Statement of Compliance pertains to this submittal, the phrase ''above sources'' is to be understood as meaning the combined air emissions from all sources registered by this submittal

  9. Complexity and accuracy of image registration methods in SPECT-guided radiation therapy

    Energy Technology Data Exchange (ETDEWEB)

    Yin, L S; Duzenli, C; Moiseenko, V [Physics and Astronomy, University of British Columbia, 6224 Agricultural Road, Vancouver, BC, V6T 1Z1 (Canada); Tang, L; Hamarneh, G [Computing Science, Simon Fraser University, 9400 TASC1, Burnaby, BC, V5A 1S6 (Canada); Gill, B [Medical Physics, Vancouver Cancer Centre, BC Cancer Agency, 600 West 10th Ave, Vancouver, BC, V5Z 4E6 (Canada); Celler, A; Shcherbinin, S [Department of Radiology, University of British Columbia, 828 West 10th Ave, Vancouver, BC, V5Z 1L8 (Canada); Fua, T F; Thompson, A; Sheehan, F [Radiation Oncology, Vancouver Cancer Centre, BC Cancer Agency, 600 West 10th Ave, Vancouver, BC, V5Z 4E6 (Canada); Liu, M [Radiation Oncology, Fraser Valley Cancer Centre, BC Cancer Agency, 13750 9th Ave, Surrey, BC, V3V 1Z2 (Canada)], E-mail: lyin@bccancer.bc.ca

    2010-01-07

    The use of functional imaging in radiotherapy treatment (RT) planning requires accurate co-registration of functional imaging scans to CT scans. We evaluated six methods of image registration for use in SPECT-guided radiotherapy treatment planning. Methods varied in complexity from 3D affine transform based on control points to diffeomorphic demons and level set non-rigid registration. Ten lung cancer patients underwent perfusion SPECT-scans prior to their radiotherapy. CT images from a hybrid SPECT/CT scanner were registered to a planning CT, and then the same transformation was applied to the SPECT images. According to registration evaluation measures computed based on the intensity difference between the registered CT images or based on target registration error, non-rigid registrations provided a higher degree of accuracy than rigid methods. However, due to the irregularities in some of the obtained deformation fields, warping the SPECT using these fields may result in unacceptable changes to the SPECT intensity distribution that would preclude use in RT planning. Moreover, the differences between intensity histograms in the original and registered SPECT image sets were the largest for diffeomorphic demons and level set methods. In conclusion, the use of intensity-based validation measures alone is not sufficient for SPECT/CT registration for RTTP. It was also found that the proper evaluation of image registration requires the use of several accuracy metrics.

  10. Efficient nonrigid registration using ranked order statistics

    DEFF Research Database (Denmark)

    Tennakoon, Ruwan B.; Bab-Hadiashar, Alireza; de Bruijne, Marleen

    2013-01-01

    of research. In this paper we propose a fast and accurate non-rigid registration method for intra-modality volumetric images. Our approach exploits the information provided by an order statistics based segmentation method, to find the important regions for registration and use an appropriate sampling scheme......Non-rigid image registration techniques are widely used in medical imaging applications. Due to high computational complexities of these techniques, finding appropriate registration method to both reduce the computation burden and increase the registration accuracy has become an intense area...... to target those areas and reduce the registration computation time. A unique advantage of the proposed method is its ability to identify the point of diminishing returns and stop the registration process. Our experiments on registration of real lung CT images, with expert annotated landmarks, show...

  11. Beating-heart registration for organ-mounted robots.

    Science.gov (United States)

    Wood, Nathan A; Schwartzman, David; Passineau, Michael J; Moraca, Robert J; Zenati, Marco A; Riviere, Cameron N

    2018-03-06

    Organ-mounted robots address the problem of beating-heart surgery by adhering to the heart, passively providing a platform that approaches zero relative motion. Because of the quasi-periodic deformation of the heart due to heartbeat and respiration, registration must address not only spatial registration but also temporal registration. Motion data were collected in the porcine model in vivo (N = 6). Fourier series models of heart motion were developed. By comparing registrations generated using an iterative closest-point approach at different phases of respiration, the phase corresponding to minimum registration distance is identified. The spatiotemporal registration technique presented here reduces registration error by an average of 4.2 mm over the 6 trials, in comparison with a more simplistic static registration that merely averages out the physiological motion. An empirical metric for spatiotemporal registration of organ-mounted robots is defined and demonstrated using data from animal models in vivo. Copyright © 2018 John Wiley & Sons, Ltd.

  12. Study on Huizhou architecture of point cloud registration based on optimized ICP algorithm

    Science.gov (United States)

    Zhang, Runmei; Wu, Yulu; Zhang, Guangbin; Zhou, Wei; Tao, Yuqian

    2018-03-01

    In view of the current point cloud registration software has high hardware requirements, heavy workload and moltiple interactive definition, the source of software with better processing effect is not open, a two--step registration method based on normal vector distribution feature and coarse feature based iterative closest point (ICP) algorithm is proposed in this paper. This method combines fast point feature histogram (FPFH) algorithm, define the adjacency region of point cloud and the calculation model of the distribution of normal vectors, setting up the local coordinate system for each key point, and obtaining the transformation matrix to finish rough registration, the rough registration results of two stations are accurately registered by using the ICP algorithm. Experimental results show that, compared with the traditional ICP algorithm, the method used in this paper has obvious time and precision advantages for large amount of point clouds.

  13. 78 FR 18586 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Acts

    Science.gov (United States)

    2013-03-27

    ...With this document, EPA is opening the public comment period for several registration reviews. Registration review is EPA's periodic review of pesticide registrations to ensure that each pesticide continues to satisfy the statutory standard for registration, that is, the pesticide can perform its intended function without unreasonable adverse effects on human health or the environment. Registration review dockets contain information that will assist the public in understanding the types of information and issues that the Agency may consider during the course of registration reviews. Through this program, EPA is ensuring that each pesticide's registration is based on current scientific and other knowledge, including its effects on human health and the environment. This document also announces the Agency's intent not to open registration review dockets for iodomethane or ethametsulfuron-methyl. Iodomethane and ethametsulfuron-methyl are undergoing phase-outs of all U.S. pesticide registrations. The cancellations of the iodomethane end use registrations became effective on December 31, 2012, and the cancellation of the sole technical product registration will become effective on December 1, 2015. The cancellations of all ethametsulfuron-methyl product registrations became effective on February 20, 2013. Therefore, iodomethane and ethametsulfuron-methyl are not scheduled for review under the registration review program. This document also announces the registration review case closures for the pesticides alkyl amine hydrochloride (case 3051) and halofenozide (case 7425), and the availability of their respective Case Closure Documents. The cancellation of all alkyl amine hydrochloride registrations became effective on October 17, 2012. The cancellation of all U.S. halofenozide registrations became effective December 21, 2012. These case closure are being announced herein with no comment period.

  14. Improving fluid registration through white matter segmentation in a twin study design

    Science.gov (United States)

    Chou, Yi-Yu; Lepore, Natasha; Brun, Caroline; Barysheva, Marina; McMahon, Katie; de Zubicaray, Greig I.; Wright, Margaret J.; Toga, Arthur W.; Thompson, Paul M.

    2010-03-01

    Robust and automatic non-rigid registration depends on many parameters that have not yet been systematically explored. Here we determined how tissue classification influences non-linear fluid registration of brain MRI. Twin data is ideal for studying this question, as volumetric correlations between corresponding brain regions that are under genetic control should be higher in monozygotic twins (MZ) who share 100% of their genes when compared to dizygotic twins (DZ) who share half their genes on average. When these substructure volumes are quantified using tensor-based morphometry, improved registration can be defined based on which method gives higher MZ twin correlations when compared to DZs, as registration errors tend to deplete these correlations. In a study of 92 subjects, higher effect sizes were found in cumulative distribution functions derived from statistical maps when performing tissue classification before fluid registration, versus fluidly registering the raw images. This gives empirical evidence in favor of pre-segmenting images for tensor-based morphometry.

  15. Installed Base Registration of Decentralised Solar Panels with Applications in Crisis Management

    Science.gov (United States)

    Aarsen, R.; Janssen, M.; Ramkisoen, M.; Biljecki, F.; Quak, W.; Verbree, E.

    2015-08-01

    In case of a calamity in the Netherlands - e.g. a dike breach - parts of the nationwide electric network can fall out. In these occasions it would be useful if decentralised energy sources of the Smart Grid would contribute to balance out the fluctuations of the energy network. Decentralised energy sources include: solar energy, wind energy, combined heat and power, and biogas. In this manner, parts of the built environment - e.g. hospitals - that are in need of a continuous power flow, could be secured of this power. When a calamity happens, information about the Smart Grid is necessary to control the crisis and to ensure a shared view on the energy networks for both the crisis managers and network operators. The current situation of publishing, storing and sharing data of solar energy has been shown a lack of reliability about the current number, physical location, and capacity of installed decentralised photovoltaic (PV) panels in the Netherlands. This study focuses on decentralised solar energy in the form of electricity via PV panels in the Netherlands and addresses this challenge by proposing a new, reliable and up-to-date database. The study reveals the requirements for a registration of the installed base of PV panels in the Netherlands. This new database should serve as a replenishment for the current national voluntary registration, called Production Installation Register of Energy Data Services Netherland (EDSN-PIR), of installed decentralised PV panel installations in the Smart Grid, and provide important information in case of a calamity.

  16. INSTALLED BASE REGISTRATION OF DECENTRALISED SOLAR PANELS WITH APPLICATIONS IN CRISIS MANAGEMENT

    Directory of Open Access Journals (Sweden)

    R. Aarsen

    2015-08-01

    Full Text Available In case of a calamity in the Netherlands - e.g. a dike breach - parts of the nationwide electric network can fall out. In these occasions it would be useful if decentralised energy sources of the Smart Grid would contribute to balance out the fluctuations of the energy network. Decentralised energy sources include: solar energy, wind energy, combined heat and power, and biogas. In this manner, parts of the built environment - e.g. hospitals - that are in need of a continuous power flow, could be secured of this power. When a calamity happens, information about the Smart Grid is necessary to control the crisis and to ensure a shared view on the energy networks for both the crisis managers and network operators. The current situation of publishing, storing and sharing data of solar energy has been shown a lack of reliability about the current number, physical location, and capacity of installed decentralised photovoltaic (PV panels in the Netherlands. This study focuses on decentralised solar energy in the form of electricity via PV panels in the Netherlands and addresses this challenge by proposing a new, reliable and up-to-date database. The study reveals the requirements for a registration of the installed base of PV panels in the Netherlands. This new database should serve as a replenishment for the current national voluntary registration, called Production Installation Register of Energy Data Services Netherland (EDSN-PIR, of installed decentralised PV panel installations in the Smart Grid, and provide important information in case of a calamity.

  17. 77 FR 74278 - Proposed Information Collection (Internet Student CPR Web Registration Application); Comment Request

    Science.gov (United States)

    2012-12-13

    ... (Internet Student CPR Web Registration Application); Comment Request AGENCY: Veterans Health Administration.... Title: Internet Student CPR Web Registration Application, VA Form 10-0468. OMB Control Number: 2900-0746... Minneapolis VA Medical Center Education Service. Students will be able to identify and register for a training...

  18. Why and how to make a REACH registration of combustion ash; Moejligheter vid REACH-registrering av energiaskor

    Energy Technology Data Exchange (ETDEWEB)

    Loevgren, Linnea; Wik, Ola

    2009-10-15

    The new chemical regulation, REACH (1997/2006/EC), Registration, Evaluation, Authorization and restriction of Chemicals, took effect the 1st of June 2007. The background to this report was the introduction of REACH and the difficulties to understand the implications for ash. The most important consequence of REACH is that all chemical substances that are manufactured, handled and used above one tonne per annum per legal entity shall be registered according to this regulation. The registration includes specifying the chemical, physical, toxicity and ecotoxicity properties of the substance and risk assessing the identified areas of use. The report describes the use of ash in connection to the waste legislation and its planned end-of-waste-criteria, the chemical legislation and the Construction Products Directive. The target audience of this report is companies producing ashes and having a use or seeing a use for its ash. The report describes how to make a REACH registration of ash independent if a company did or did not pre-register ash during 2008. It describes how to change from one ash registration into another if the pre-registration was done for one type of ash but the company changes opinion during the sameness check, i.e. changing SIEF (Appendix A). Taking part in REACH registration projects during 2009-2010 can be advantageous since knowledge and financing are shared. Ash can be REACH registered also in the future but it is important to know that the registration have to be done prior the production and marketing starts. If ash is consider to be a waste the handling is covered by the community and national waste legislation. In Sweden ashes are by and large being regarded as waste, and recycling is risk assessed and permits are given case by case. End-of-waste criteria for different waste material are being elaborated within the EU. Such criteria will among other details cover chemical safety. When a material fulfils the end-of-waste criteria such material

  19. Challenging an immediate suspension of a DEA registration: is it time for a new tact?

    Science.gov (United States)

    Behr, Douglas J

    2014-01-01

    A Drug Enforcement Administration ("DEA") registration is not only a necessity, but also an invaluable commodity for doctors, pharmacists, hospitals and drug wholesalers who prescribe, stock, and distribute controlled substances. While the DEA may only suspend a registration by issuing an immediate suspension order ("ISO) after an ex parte finding of "imminent danger to the public health or safety," the law fails to explicitly protect the registrant by way of a post-suspension hearing on the ISO, despite the registrant's constitutionally protected property interest in the registration. A registrant has only two procedural options--which are often unsuccessful--to challenge the ISO: endure a long and arduous administrative review proceeding or petition the court for a "not-so-easily proven" injunction, all the while the suspension remains in effect and the controlled substance business operations cease. Accordingly, a suspension of the registration may be certain death to doctors and pharmacists without the financial means to operate the business in the absence of the registration. Because the DEA registration is a constitutionally-protected interest, there is a better way to challenge the suspension. The Supreme Court has held that once a license is issued, the continued possession of it is essential to the registrant's livelihood. Therefore suspension or revocation of such a protected interest requires due process. Due-process hearings, while varied, will provide the necessary avenues of review to provide a fair review of the justification of the suspension and its continuance, i.e., whether there truly is imminent danger to public health or safety and whether the suspension is overbroad and should be limited. To date, this thesis remains to be tested and awaits a petitioner with a justiciable claim and the financial resources to challenge the DEA in court. But in the field of DEA ISO challenges, it is time for a new tact!

  20. Localization and registration accuracy in image guided neurosurgery: a clinical study

    Energy Technology Data Exchange (ETDEWEB)

    Shamir, Reuben R.; Joskowicz, Leo [Hebrew University of Jerusalem, School of Engineering and Computer Science, Jerusalem (Israel); Spektor, Sergey; Shoshan, Yigal [Hadassah University Hospital, Department of Neurosurgery, School of Medicine, Jerusalem (Israel)

    2009-01-15

    To measure and compare the clinical localization and registration errors in image-guided neurosurgery, with the purpose of revising current assumptions. Twelve patients who underwent brain surgeries with a navigation system were randomly selected. A neurosurgeon localized and correlated the landmarks on preoperative MRI images and on the intraoperative physical anatomy with a tracked pointer. In the laboratory, we generated 612 scenarios in which one landmark pair was defined as the target and the remaining ones were used to compute the registration transformation. Four errors were measured: (1) fiducial localization error (FLE); (2) target registration error (TRE); (3) fiducial registration error (FRE); (4) Fitzpatrick's target registration error estimation (F-TRE). We compared the different errors and computed their correlation. The image and physical FLE ranges were 0.5-2.0 and 1.6-3.0 mm, respectively. The measured TRE, FRE and F-TRE were 4.1{+-}1.6, 3.9{+-}1.2, and 3.7{+-}2.2 mm, respectively. Low correlations of 0.19 and 0.37 were observed between the FRE and TRE and between the F-TRE and the TRE, respectively. The differences of the FRE and F-TRE from the TRE were 1.3{+-}1.0 mm (max=5.5 mm) and 1.3{+-}1.2 mm (max=7.3 mm), respectively. Contrary to common belief, the FLE presents significant variations. Moreover, both the FRE and the F-TRE are poor indicators of the TRE in image-to-patient registration. (orig.)

  1. Performance of the IEEE 802.3 EPON registration scheme under high load

    Science.gov (United States)

    Bhatia, Swapnil P.; Bartos, Radim

    2004-09-01

    The proposed standard for the IEEE 802.3 Ethernet Passive Optical Network includes a random delayed transmission scheme for registration of new nodes. Although the scheme performs well on low loads, our simulation demonstrates the degraded and undesirable performance of the scheme at higher loads. We propose a simple modification to the current scheme that increases its range of operation and is compatible with the IEEE draft standard. We demonstrate the improvement in performance gained without any significant increase in registration delay.

  2. Electrolytic tritium enrichment: Current control using current-stabilised Kepco Type JQE modular supplies

    International Nuclear Information System (INIS)

    1976-01-01

    This note describes the principles, design and operation of a current-stabilised power source for tritium electrolytic enrichment cells. A Kepoo Tpe JE, modular supply is current-stabilised by controlled current feedback. The accompanying control unit incorporates a temperature sensor or the cooling unit of the electrolysis cells, a line monitor to register current shut-off due to temporary power failure, a time-of-day clock, a current control potentiometer and a digital voltmeter providing current reading to an accuracy of 0.01A

  3. Electrolytic tritium enrichment: Current control using current-stabilised Kepco Type JQE modular supplies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1976-07-12

    This note describes the principles, design and operation of a current-stabilised power source for tritium electrolytic enrichment cells. A Kepoo Tpe JE, modular supply is current-stabilised by controlled current feedback. The accompanying control unit incorporates a temperature sensor or the cooling unit of the electrolysis cells, a line monitor to register current shut-off due to temporary power failure, a time-of-day clock, a current control potentiometer and a digital voltmeter providing current reading to an accuracy of 0.01A.

  4. An accelerated image matching technique for UAV orthoimage registration

    Science.gov (United States)

    Tsai, Chung-Hsien; Lin, Yu-Ching

    2017-06-01

    Using an Unmanned Aerial Vehicle (UAV) drone with an attached non-metric camera has become a popular low-cost approach for collecting geospatial data. A well-georeferenced orthoimage is a fundamental product for geomatics professionals. To achieve high positioning accuracy of orthoimages, precise sensor position and orientation data, or a number of ground control points (GCPs), are often required. Alternatively, image registration is a solution for improving the accuracy of a UAV orthoimage, as long as a historical reference image is available. This study proposes a registration scheme, including an Accelerated Binary Robust Invariant Scalable Keypoints (ABRISK) algorithm and spatial analysis of corresponding control points for image registration. To determine a match between two input images, feature descriptors from one image are compared with those from another image. A "Sorting Ring" is used to filter out uncorrected feature pairs as early as possible in the stage of matching feature points, to speed up the matching process. The results demonstrate that the proposed ABRISK approach outperforms the vector-based Scale Invariant Feature Transform (SIFT) approach where radiometric variations exist. ABRISK is 19.2 times and 312 times faster than SIFT for image sizes of 1000 × 1000 pixels and 4000 × 4000 pixels, respectively. ABRISK is 4.7 times faster than Binary Robust Invariant Scalable Keypoints (BRISK). Furthermore, the positional accuracy of the UAV orthoimage after applying the proposed image registration scheme is improved by an average of root mean square error (RMSE) of 2.58 m for six test orthoimages whose spatial resolutions vary from 6.7 cm to 10.7 cm.

  5. 40 CFR 164.21 - Contents of a denial of registration, notice of intent to cancel a registration, or notice of...

    Science.gov (United States)

    2010-07-01

    ..., notice of intent to cancel a registration, or notice of intent to change a classification. 164.21 Section... denial of registration, notice of intent to cancel a registration, or notice of intent to change a classification. (a) Contents. The denial of registration or a notice of intent to cancel a registration or to...

  6. System for Earth Sample Registration SESAR: Services for IGSN Registration and Sample Metadata Management

    Science.gov (United States)

    Chan, S.; Lehnert, K. A.; Coleman, R. J.

    2011-12-01

    SESAR, the System for Earth Sample Registration, is an online registry for physical samples collected for Earth and environmental studies. SESAR generates and administers the International Geo Sample Number IGSN, a unique identifier for samples that is dramatically advancing interoperability amongst information systems for sample-based data. SESAR was developed to provide the complete range of registry services, including definition of IGSN syntax and metadata profiles, registration and validation of name spaces requested by users, tools for users to submit and manage sample metadata, validation of submitted metadata, generation and validation of the unique identifiers, archiving of sample metadata, and public or private access to the sample metadata catalog. With the development of SESAR v3, we placed particular emphasis on creating enhanced tools that make metadata submission easier and more efficient for users, and that provide superior functionality for users to manage metadata of their samples in their private workspace MySESAR. For example, SESAR v3 includes a module where users can generate custom spreadsheet templates to enter metadata for their samples, then upload these templates online for sample registration. Once the content of the template is uploaded, it is displayed online in an editable grid format. Validation rules are executed in real-time on the grid data to ensure data integrity. Other new features of SESAR v3 include the capability to transfer ownership of samples to other SESAR users, the ability to upload and store images and other files in a sample metadata profile, and the tracking of changes to sample metadata profiles. In the next version of SESAR (v3.5), we will further improve the discovery, sharing, registration of samples. For example, we are developing a more comprehensive suite of web services that will allow discovery and registration access to SESAR from external systems. Both batch and individual registrations will be possible

  7. Effectiveness of transcranial direct current stimulation preceding cognitive behavioural management for chronic low back pain: sham controlled double blinded randomised controlled trial.

    Science.gov (United States)

    Luedtke, Kerstin; Rushton, Alison; Wright, Christine; Jürgens, Tim; Polzer, Astrid; Mueller, Gerd; May, Arne

    2015-04-16

    .Trial registration Current controlled trials ISRCTN89874874. © Luedtke et al 2015.

  8. [Study on the reform and improvement of the medical device registration system in China].

    Science.gov (United States)

    Wang, Lanming

    2012-11-01

    Based on the theories of the Government Regulation and Administrative Licensure, aiming at the current situations of medical device registration system in China, some policy suggestions for future reform and improvement were provided as follows. (1) change the concepts of medical device registration administration. (2) perfect the regulations of medical device registration administration. (3) reform the medical device review organizational system. (4) Optimize the procedure of review and approval. (5) set up and maintain a professional team of review and approval staff. (6) reinforce the post-marketing supervision of medical devices. (7) foster and bring into play of the role of non-government organizations.

  9. 46 CFR 402.220 - Registration of pilots.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Registration of pilots. 402.220 Section 402.220 Shipping... ORDERS Registration of Pilots § 402.220 Registration of pilots. (a) Each applicant pilot must complete the number of round trips specified in this section prior to registration as a U.S. registered pilot...

  10. A novel 3D volumetric voxel registration technique for volume-view-guided image registration of multiple imaging modalities

    International Nuclear Information System (INIS)

    Li Guang; Xie Huchen; Ning, Holly; Capala, Jacek; Arora, Barbara C.; Coleman, C. Norman; Camphausen, Kevin; Miller, Robert W.

    2005-01-01

    Purpose: To provide more clinically useful image registration with improved accuracy and reduced time, a novel technique of three-dimensional (3D) volumetric voxel registration of multimodality images is developed. Methods and Materials: This technique can register up to four concurrent images from multimodalities with volume view guidance. Various visualization effects can be applied, facilitating global and internal voxel registration. Fourteen computed tomography/magnetic resonance (CT/MR) image sets and two computed tomography/positron emission tomography (CT/PET) image sets are used. For comparison, an automatic registration technique using maximization of mutual information (MMI) and a three-orthogonal-planar (3P) registration technique are used. Results: Visually sensitive registration criteria for CT/MR and CT/PET have been established, including the homogeneity of color distribution. Based on the registration results of 14 CT/MR images, the 3D voxel technique is in excellent agreement with the automatic MMI technique and is indicatory of a global positioning error (defined as the means and standard deviations of the error distribution) using the 3P pixel technique: 1.8 deg ± 1.2 deg in rotation and 2.0 ± 1.3 (voxel unit) in translation. To the best of our knowledge, this is the first time that such positioning error has been addressed. Conclusion: This novel 3D voxel technique establishes volume-view-guided image registration of up to four modalities. It improves registration accuracy with reduced time, compared with the 3P pixel technique. This article suggests that any interactive and automatic registration should be safeguarded using the 3D voxel technique

  11. Brief Comment on the Draft Land Administration, Use, Registration ...

    African Journals Online (AJOL)

    D_Behailu

    The draft 'Land Administration, Use, Registration and Plan Proclamation (2007. EC)' has been in circulation for a while now. One of the prime objectives of the draft law is to address various counterproductive restrictions in the current federal land proclamation. According to its preamble, the draft aspires to expand the rights ...

  12. Automatic vertebral identification using surface-based registration

    Science.gov (United States)

    Herring, Jeannette L.; Dawant, Benoit M.

    2000-06-01

    This work introduces an enhancement to currently existing methods of intra-operative vertebral registration by allowing the portion of the spinal column surface that correctly matches a set of physical vertebral points to be automatically selected from several possible choices. Automatic selection is made possible by the shape variations that exist among lumbar vertebrae. In our experiments, we register vertebral points representing physical space to spinal column surfaces extracted from computed tomography images. The vertebral points are taken from the posterior elements of a single vertebra to represent the region of surgical interest. The surface is extracted using an improved version of the fully automatic marching cubes algorithm, which results in a triangulated surface that contains multiple vertebrae. We find the correct portion of the surface by registering the set of physical points to multiple surface areas, including all vertebral surfaces that potentially match the physical point set. We then compute the standard deviation of the surface error for the set of points registered to each vertebral surface that is a possible match, and the registration that corresponds to the lowest standard deviation designates the correct match. We have performed our current experiments on two plastic spine phantoms and one patient.

  13. Spherical Demons: Fast Surface Registration

    Science.gov (United States)

    Yeo, B.T. Thomas; Sabuncu, Mert; Vercauteren, Tom; Ayache, Nicholas; Fischl, Bruce; Golland, Polina

    2009-01-01

    We present the fast Spherical Demons algorithm for registering two spherical images. By exploiting spherical vector spline interpolation theory, we show that a large class of regularizers for the modified demons objective function can be efficiently implemented on the sphere using convolution. Based on the one parameter subgroups of diffeomorphisms, the resulting registration is diffeomorphic and fast – registration of two cortical mesh models with more than 100k nodes takes less than 5 minutes, comparable to the fastest surface registration algorithms. Moreover, the accuracy of our method compares favorably to the popular FreeSurfer registration algorithm. We validate the technique in two different settings: (1) parcellation in a set of in-vivo cortical surfaces and (2) Brodmann area localization in ex-vivo cortical surfaces. PMID:18979813

  14. Accelerated gradient-based free form deformable registration for online adaptive radiotherapy

    International Nuclear Information System (INIS)

    Yu, Gang; Yang, Guanyu; Shu, Huazhong; Li, Baosheng; Liang, Yueqiang; Yin, Yong; Li, Dengwang

    2015-01-01

    The registration of planning fan-beam computed tomography (FBCT) and daily cone-beam CT (CBCT) is a crucial step in adaptive radiation therapy. The current intensity-based registration algorithms, such as Demons, may fail when they are used to register FBCT and CBCT, because the CT numbers in CBCT cannot exactly correspond to the electron densities. In this paper, we investigated the effects of CBCT intensity inaccuracy on the registration accuracy and developed an accurate gradient-based free form deformation algorithm (GFFD). GFFD distinguishes itself from other free form deformable registration algorithms by (a) measuring the similarity using the 3D gradient vector fields to avoid the effect of inconsistent intensities between the two modalities; (b) accommodating image sampling anisotropy using the local polynomial approximation-intersection of confidence intervals (LPA-ICI) algorithm to ensure a smooth and continuous displacement field; and (c) introducing a ‘bi-directional’ force along with an adaptive force strength adjustment to accelerate the convergence process. It is expected that such a strategy can decrease the effect of the inconsistent intensities between the two modalities, thus improving the registration accuracy and robustness. Moreover, for clinical application, the algorithm was implemented by graphics processing units (GPU) through OpenCL framework. The registration time of the GFFD algorithm for each set of CT data ranges from 8 to 13 s. The applications of on-line adaptive image-guided radiation therapy, including auto-propagation of contours, aperture-optimization and dose volume histogram (DVH) in the course of radiation therapy were also studied by in-house-developed software. (paper)

  15. Localization and registration accuracy in image guided neurosurgery: a clinical study

    International Nuclear Information System (INIS)

    Shamir, Reuben R.; Joskowicz, Leo; Spektor, Sergey; Shoshan, Yigal

    2009-01-01

    To measure and compare the clinical localization and registration errors in image-guided neurosurgery, with the purpose of revising current assumptions. Twelve patients who underwent brain surgeries with a navigation system were randomly selected. A neurosurgeon localized and correlated the landmarks on preoperative MRI images and on the intraoperative physical anatomy with a tracked pointer. In the laboratory, we generated 612 scenarios in which one landmark pair was defined as the target and the remaining ones were used to compute the registration transformation. Four errors were measured: (1) fiducial localization error (FLE); (2) target registration error (TRE); (3) fiducial registration error (FRE); (4) Fitzpatrick's target registration error estimation (F-TRE). We compared the different errors and computed their correlation. The image and physical FLE ranges were 0.5-2.0 and 1.6-3.0 mm, respectively. The measured TRE, FRE and F-TRE were 4.1±1.6, 3.9±1.2, and 3.7±2.2 mm, respectively. Low correlations of 0.19 and 0.37 were observed between the FRE and TRE and between the F-TRE and the TRE, respectively. The differences of the FRE and F-TRE from the TRE were 1.3±1.0 mm (max=5.5 mm) and 1.3±1.2 mm (max=7.3 mm), respectively. Contrary to common belief, the FLE presents significant variations. Moreover, both the FRE and the F-TRE are poor indicators of the TRE in image-to-patient registration. (orig.)

  16. 32 CFR 634.19 - Registration policy.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Registration policy. 634.19 Section 634.19 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Motor Vehicle Registration § 634.19 Registration policy. (a) Motor vehicles will be...

  17. Nonrigid registration with tissue-dependent filtering of the deformation field

    International Nuclear Information System (INIS)

    Staring, Marius; Klein, Stefan; Pluim, Josien P W

    2007-01-01

    In present-day medical practice it is often necessary to nonrigidly align image data. Current registration algorithms do not generally take the characteristics of tissue into account. Consequently, rigid tissue, such as bone, can be deformed elastically, growth of tumours may be concealed, and contrast-enhanced structures may be reduced in volume. We propose a method to locally adapt the deformation field at structures that must be kept rigid, using a tissue-dependent filtering technique. This adaptive filtering of the deformation field results in locally linear transformations without scaling or shearing. The degree of filtering is related to tissue stiffness: more filtering is applied at stiff tissue locations, less at parts of the image containing nonrigid tissue. The tissue-dependent filter is incorporated in a commonly used registration algorithm, using mutual information as a similarity measure and cubic B-splines to model the deformation field. The new registration algorithm is compared with this popular method. Evaluation of the proposed tissue-dependent filtering is performed on 3D computed tomography (CT) data of the thorax and on 2D digital subtraction angiography (DSA) images. The results show that tissue-dependent filtering of the deformation field leads to improved registration results: tumour volumes and vessel widths are preserved rather than affected

  18. A pivotal registration phase III, multicenter, randomized tuberculosis controlled trial: design issues and lessons learnt from the Gatifloxacin for TB (OFLOTUB project

    Directory of Open Access Journals (Sweden)

    Merle Corinne SC

    2012-05-01

    Full Text Available Abstract Background There have been no major advances in tuberculosis (TB drug development since the first East African/British Medical Research Council short course chemotherapy trial 35 years ago. Since then, the landscape for conducting TB clinical trials has profoundly changed with the emergence of HIV infection, the spread of resistant TB bacilli strains, recent advances in mycobacteriological capacity, and drug discovery. As a consequence questions have arisen on the most appropriate approach to design and conduct current TB trials. To highlight key issues discussed: Is a superiority, equivalence, or non-inferiority design most appropriate? What should be the primary efficacy outcome? How to consider re-infections in the definition of the outcome? What is the optimal length of patient follow-up? Is blinding appropriate when treatment duration in test arm is shorter? What are the appropriate assumptions for sample size calculation? Methods Various drugs are currently in the development pipeline. We are presenting in this paper the design of the most recently completed phase III TB trial, the OFLOTUB project, which is the pivotal trial of a registration portfolio for a gatifloxacin-containing TB regimen. It is a randomized, open-label, multicenter, controlled trial aiming to evaluate the efficacy and safety of a gatifloxacin-containing 4-month regimen (trial registration: ClinicalTrial.gov database: NCT00216385. Results In the light of the recent scientific and regulatory discussions, we discuss some of the design issues in TB clinical trials and more specifically the reasons that guided our choices, in order to best answer the trial objectives, while at the same time satisfying regulatory authority requirements. Conclusion When shortening TB treatment, we are advocating for a non-inferiority, non-blinded design, with a composite unfavorable endpoint assessed 12 months post treatment completion, and added trial procedures specifically

  19. The First 500 Registrations to the Research Registry®: Advancing Registration of Under-registered Study Types

    Directory of Open Access Journals (Sweden)

    Riaz Agha

    2016-09-01

    Full Text Available The Declaration of Helsinki 2013 encourages the registration of all research studies involving human participants. However, emphasis has been placed on prospective clinical trials, and it is estimated that only 10% of observational studies are registered. In response, Research Registry® was launched in February 2015; a retrospectively curated registry that is free and easy to use. Research Registry® enables prospective or retrospective registration of studies, including those study types that cannot be registered on existing registries. In this study, we describe the first 500 registrations on Research Registry®.Since the launch of Research Registry® in February 2015, data of registrations have been collected, including type of studies registered, country of origin and data curation activity. Inappropriate registrations, such as duplicates, were identified by the data curation process. These were removed from the database or modified as required. A quality score was assigned for each registration, based on Bradford-Hill’s criteria on what research studies should convey. Changes in quality scores over time were assessed. 500 studies were registered on Research Registry® from February 2015 to October 2015, with a total of 1.7 million patients enrolled. The most common study types were retrospective cohort studies (37.2%, case series (14.8% and first-in-man case reports (10.4%. Registrations were received from 57 different countries; the most submissions were received from Turkey, followed by China and the United Kingdom. Retrospective data curation identified 80 studies that were initially registered as the incorrect study type, and were subsequently correct. The Kruskal-Wallis test identified a significant improvement in quality scores for registrations from February 2015 to October 2015 (p < 0.0001.Since its conception in February 2015, Research Registry® has established itself as a new registry that is free, easy to use and enables the

  20. The First 500 Registrations to the Research Registry®: Advancing Registration of Under-Registered Study Types.

    Science.gov (United States)

    Agha, Riaz; Fowler, Alexander J; Limb, Christopher; Al Omran, Yasser; Sagoo, Harkiran; Koshy, Kiron; Jafree, Daniyal J; Anwar, Mohammed Omer; McCullogh, Peter; Orgill, Dennis Paul

    2016-01-01

    The Declaration of Helsinki 2013 encourages the registration of all research studies involving human participants. However, emphasis has been placed on prospective clinical trials, and it is estimated that only 10% of observational studies are registered. In response, Research Registry ® was launched in February 2015; a retrospectively curated registry that is free and easy to use. Research Registry ® enables prospective or retrospective registration of studies, including those study types that cannot be registered on existing registries. In this study, we describe the first 500 registrations on Research Registry ® . Since the launch of Research Registry ® in February 2015, data of registrations have been collected, including type of studies registered, country of origin, and data curation activity. Inappropriate registrations, such as duplicates, were identified by the data curation process. These were removed from the database or modified as required. A quality score was assigned for each registration, based on Sir Austin Bradford Hill's criteria on what research studies should convey. Changes in quality scores over time were assessed. A total of 500 studies were registered on Research Registry ® from February 2015 to October 2015, with a total of 1.7 million patients enrolled. The most common study types were retrospective cohort studies (37.2%), case series (14.8%), and first-in-man case reports (10.4%). Registrations were received from 57 different countries; the most submissions were received from Turkey, followed by China and the United Kingdom. Retrospective data curation identified 80 studies that were initially registered as the incorrect study type, and were subsequently correct. The Kruskal-Wallis test identified a significant improvement in quality scores for registrations from February 2015 to October 2015 ( p  < 0.0001). Since its conception in February 2015, Research Registry ® has established itself as a new registry that is free, easy to

  1. Registration factors that limit international mobility of people holding physiotherapy qualifications: A systematic review.

    Science.gov (United States)

    Foo, Jonathan S; Storr, Michael; Maloney, Stephen

    2016-06-01

    There is no enforced international standardisation of the physiotherapy profession. Thus, registration is used in many countries to maintain standards of care and to protect the public. However, registration may also limit international workforce mobility. What is known about the professional registration factors that may limit the international mobility of people holding physiotherapy qualifications? Systematic review using an electronic database search and hand searching of the World Confederation for Physical Therapy and International Network of Physiotherapy Regulatory Authorities websites. Analysis was conducted using thematic analysis. 10 articles and eight websites were included from the search strategy. Data is representative of high-income English speaking countries. Four themes emerged regarding limitations to professional mobility: practice context, qualification recognition, verification of fitness to practice, and incidental limitations arising from the registration process. Professional mobility is limited by differences in physiotherapy education programmes, resulting in varying standards of competency. Thus, it is often necessary to verify clinical competencies through assessments, as well as determining professional attributes and ability to apply competencies in a different practice context, as part of the registration process. There has been little evaluation of registration practices, and at present, there is a need to re-evaluate current registration processes to ensure they are efficient and effective, thereby enhancing workforce mobility. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  2. Nonlinear Deadbeat Current Control of a Switched Reluctance Motor

    OpenAIRE

    Rudolph, Benjamin

    2009-01-01

    High performance current control is critical to the success of the switched reluctance motor (SRM). Yet high motor phase nonlinearities in the SRM place extra burden on the current controller, rendering it the weakest link in SRM control. In contrast to linear motor control techniques that respond to current error, the deadbeat controller calculates the control voltage by the current command, phase current, rotor position and applied phase voltage. The deadbeat controller has demonstrated sup...

  3. Registration of Urban Aerial Image and LiDAR Based on Line Vectors

    Directory of Open Access Journals (Sweden)

    Qinghong Sheng

    2017-09-01

    Full Text Available In a traditional registration of a single aerial image with airborne light detection and ranging (LiDAR data using linear features that regard line direction as a control or linear features as constraints in the solution, lacking the constraint of linear position leads to the error propagation of the adjustment model. To solve this problem, this paper presents a line vector-based registration mode (LVR in which image rays and LiDAR lines are expressed by a line vector that integrates the line direction and the line position. A registration equation of line vector is set up by coplanar imaging rays and corresponding control lines. Three types of datasets consisting of synthetic, theInternational Society for Photogrammetry and Remote Sensing (ISPRS test project, and real aerial data are used. A group of progressive experiments is undertaken to evaluate the robustness of the LVR. Experimental results demonstrate that the integrated line direction and the line position contributes a great deal to the theoretical and real accuracies of the unknowns, as well as the stability of the adjustment model. This paper provides a new suggestion that, for a single image and LiDAR data, registration in urban areas can be accomplished by accommodating rich line features.

  4. Comparison of carina-based versus bony anatomy-based registration for setup verification in esophageal cancer radiotherapy.

    Science.gov (United States)

    Machiels, Mélanie; Jin, Peng; van Gurp, Christianne H; van Hooft, Jeanin E; Alderliesten, Tanja; Hulshof, Maarten C C M

    2018-03-21

    To investigate the feasibility and geometric accuracy of carina-based registration for CBCT-guided setup verification in esophageal cancer IGRT, compared with current practice bony anatomy-based registration. Included were 24 esophageal cancer patients with 65 implanted fiducial markers, visible on planning CTs and follow-up CBCTs. All available CBCT scans (n = 236) were rigidly registered to the planning CT with respect to the bony anatomy and the carina. Target coverage was visually inspected and marker position variation was quantified relative to both registration approaches; the variation of systematic (Σ) and random errors (σ) was estimated. Automatic carina-based registration was feasible in 94.9% of the CBCT scans, with an adequate target coverage in 91.1% compared to 100% after bony anatomy-based registration. Overall, Σ (σ) in the LR/CC/AP direction was 2.9(2.4)/4.1(2.4)/2.2(1.8) mm using the bony anatomy registration compared to 3.3(3.0)/3.6(2.6)/3.9(3.1) mm for the carina. Mid-thoracic placed markers showed a non-significant but smaller Σ in CC and AP direction when using the carina-based registration. Compared with a bony anatomy-based registration, carina-based registration for esophageal cancer IGRT results in inadequate target coverage in 8.9% of cases. Furthermore, large Σ and σ, requiring larger anisotropic margins, were seen after carina-based registration. Only for tumors entirely confined to the mid-thoracic region the carina-based registration might be slightly favorable.

  5. Locally orderless registration code

    DEFF Research Database (Denmark)

    2012-01-01

    This is code for the TPAMI paper "Locally Orderless Registration". The code requires intel threadding building blocks installed and is provided for 64 bit on mac, linux and windows.......This is code for the TPAMI paper "Locally Orderless Registration". The code requires intel threadding building blocks installed and is provided for 64 bit on mac, linux and windows....

  6. Image-guided radiotherapy quality control: Statistical process control using image similarity metrics.

    Science.gov (United States)

    Shiraishi, Satomi; Grams, Michael P; Fong de Los Santos, Luis E

    2018-05-01

    , respectively. Patient-specific control charts using NCC evaluated daily variation and identified statistically significant deviations. This study also showed that subjective evaluations of the images were not always consistent. Population control charts identified a patient whose tracking metrics were significantly lower than those of other patients. The patient-specific action limits identified registrations that warranted immediate evaluation by an expert. When effective displacements in the anterior-posterior direction were compared to 3DoF couch displacements, the agreement was ±1 mm for seven of 10 patients for both C-spine and mandible RTVs. Qualitative review alone of IGRT images can result in inconsistent feedback to the IGRT process. Registration tracking using NCC objectively identifies statistically significant deviations. When used in conjunction with the current image review process, this tool can assist in improving the safety and consistency of the IGRT process. © 2018 American Association of Physicists in Medicine.

  7. Current control system for superconducting coils of LHD

    International Nuclear Information System (INIS)

    Chikaraishi, H.; Yamada, S.; Inoue, T.

    1996-01-01

    This paper introduce a coil current control system of the LHD. The main part of this system consists of two VME based real time computers and a risc based work station which are connected by optical fiber link. In this computer system, a coil current controller for steady state operation of LHD which based on a state variable control theory is installed. Also advanced current control scheme, which are now developing for dynamic current control in phase II operation of LHD, are introduced. (author)

  8. Feasibility analysis of high resolution tissue image registration using 3-D synthetic data

    Directory of Open Access Journals (Sweden)

    Yachna Sharma

    2011-01-01

    Full Text Available Background: Registration of high-resolution tissue images is a critical step in the 3D analysis of protein expression. Because the distance between images (~4-5μm thickness of a tissue section is nearly the size of the objects of interest (~10-20μm cancer cell nucleus, a given object is often not present in both of two adjacent images. Without consistent correspondence of objects between images, registration becomes a difficult task. This work assesses the feasibility of current registration techniques for such images. Methods: We generated high resolution synthetic 3-D image data sets emulating the constraints in real data. We applied multiple registration methods to the synthetic image data sets and assessed the registration performance of three techniques (i.e., mutual information (MI, kernel density estimate (KDE method [1], and principal component analysis (PCA at various slice thicknesses (with increments of 1μm in order to quantify the limitations of each method. Results: Our analysis shows that PCA, when combined with the KDE method based on nuclei centers, aligns images corresponding to 5μm thick sections with acceptable accuracy. We also note that registration error increases rapidly with increasing distance between images, and that the choice of feature points which are conserved between slices improves performance. Conclusions: We used simulation to help select appropriate features and methods for image registration by estimating best-case-scenario errors for given data constraints in histological images. The results of this study suggest that much of the difficulty of stained tissue registration can be reduced to the problem of accurately identifying feature points, such as the center of nuclei.

  9. 78 FR 33442 - Manufacturer of Controlled Substances; Notice of Registration; GE Healthcare

    Science.gov (United States)

    2013-06-04

    ... II. The company plans to manufacture a radioactive product to diagnose Parkinson's disease; and to... physical security systems, verification of the company's compliance with state and local laws, and a review... received. DEA has considered the factors in 21 U.S.C. 823(a), and determined that the registration of GE...

  10. A comparison of publicly available linear MRI stereotaxic registration techniques.

    Science.gov (United States)

    Dadar, Mahsa; Fonov, Vladimir S; Collins, D Louis

    2018-07-01

    Linear registration to a standard space is one of the major steps in processing and analyzing magnetic resonance images (MRIs) of the brain. Here we present an overview of linear stereotaxic MRI registration and compare the performance of 5 publicly available and extensively used linear registration techniques in medical image analysis. A set of 9693 T1-weighted MR images were obtained for testing from 4 datasets: ADNI, PREVENT-AD, PPMI, and HCP, two of which have multi-center and multi-scanner data and three of which have longitudinal data. Each individual native image was linearly registered to the MNI ICBM152 average template using five versions of MRITOTAL from MINC tools, FLIRT from FSL, two versions of Elastix, spm_affreg from SPM, and ANTs linear registration techniques. Quality control (QC) images were generated from the registered volumes and viewed by an expert rater to assess the quality of the registrations. The QC image contained 60 sub-images (20 of each of axial, sagittal, and coronal views at different levels throughout the brain) overlaid with contours of the ICBM152 template, enabling the expert rater to label the registration as acceptable or unacceptable. The performance of the registration techniques was then compared across different datasets. In addition, the effect of image noise, intensity non-uniformity, age, head size, and atrophy on the performance of the techniques was investigated by comparing differences between age, scaling factor, ventricle volume, brain volume, and white matter hyperintensity (WMH) volumes between passed and failed cases for each method. The average registration failure rate among all datasets was 27.41%, 27.14%, 12.74%, 13.03%, 0.44% for the five versions of MRITOTAL techniques, 8.87% for ANTs, 11.11% for FSL, 12.35% for Elastix Affine, 24.40% for Elastix Similarity, and 30.66% for SPM. There were significant effects of signal to noise ratio, image intensity non-uniformity estimates, as well as age, head size, and

  11. Medical Image Registration and Surgery Simulation

    DEFF Research Database (Denmark)

    Bro-Nielsen, Morten

    1996-01-01

    This thesis explores the application of physical models in medical image registration and surgery simulation. The continuum models of elasticity and viscous fluids are described in detail, and this knowledge is used as a basis for most of the methods described here. Real-time deformable models......, and the use of selective matrix vector multiplication. Fluid medical image registration A new and faster algorithm for non-rigid registration using viscous fluid models is presented. This algorithm replaces the core part of the original algorithm with multi-resolution convolution using a new filter, which...... growth is also presented. Using medical knowledge about the growth processes of the mandibular bone, a registration algorithm for time sequence images of the mandible is developed. Since this registration algorithm models the actual development of the mandible, it is possible to simulate the development...

  12. Medical image registration for analysis

    International Nuclear Information System (INIS)

    Petrovic, V.

    2006-01-01

    Full text: Image registration techniques represent a rich family of image processing and analysis tools that aim to provide spatial correspondences across sets of medical images of similar and disparate anatomies and modalities. Image registration is a fundamental and usually the first step in medical image analysis and this paper presents a number of advanced techniques as well as demonstrates some of the advanced medical image analysis techniques they make possible. A number of both rigid and non-rigid medical image alignment algorithms of equivalent and merely consistent anatomical structures respectively are presented. The algorithms are compared in terms of their practical aims, inputs, computational complexity and level of operator (e.g. diagnostician) interaction. In particular, the focus of the methods discussion is placed on the applications and practical benefits of medical image registration. Results of medical image registration on a number of different imaging modalities and anatomies are presented demonstrating the accuracy and robustness of their application. Medical image registration is quickly becoming ubiquitous in medical imaging departments with the results of such algorithms increasingly used in complex medical image analysis and diagnostics. This paper aims to demonstrate at least part of the reason why

  13. Sliding Mode Control of Induction Motor Phase Currents

    DEFF Research Database (Denmark)

    Hansen, R.B.; Hattel, T.; Bork, J

    1995-01-01

    Sliding mode control of induction motor phase currents are investigated through development of two control concepts.......Sliding mode control of induction motor phase currents are investigated through development of two control concepts....

  14. 40 CFR 68.160 - Registration.

    Science.gov (United States)

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Risk Management Plan § 68.160 Registration. (a) The owner or operator shall... substances handled in covered processes. (b) The registration shall include the following data: (1...

  15. Historical Image Registration and Land-Use Land-Cover Change Analysis

    Directory of Open Access Journals (Sweden)

    Fang-Ju Jao

    2014-12-01

    Full Text Available Historical aerial images are important to retain past ground surface information. The land-use land-cover change in the past can be identified using historical aerial images. Automatic historical image registration and stitching is essential because the historical image pose information was usually lost. In this study, the Scale Invariant Feature Transform (SIFT algorithm was used for feature extraction. Subsequently, the present study used the automatic affine transformation algorithm for historical image registration, based on SIFT features and control points. This study automatically determined image affine parameters and simultaneously transformed from an image coordinate system to a ground coordinate system. After historical aerial image registration, the land-use land-cover change was analyzed between two different years (1947 and 1975 at the Tseng Wen River estuary. Results show that sandbars and water zones were transformed into a large number of fish ponds between 1947 and 1975.

  16. Stator Current Harmonic Control with Resonant Controller for Doubly Fed Induction Generator

    DEFF Research Database (Denmark)

    Liu, Changjin; Blaabjerg, Frede; Chen, Wenjie

    2012-01-01

    rotor current control loop for harmonic suppression. The overall control scheme is implemented in dq frame. Based on a mathematical model of the DFIG control system, the effects on system stability using the resonant controller, an analysis of the steady-state error, and the dynamic performance......, are discussed in this paper. Taking these effects into account, the parameters of the resonant controller can be designed and effectively damp the influence from the grid voltage harmonics. As a result, the impacts of the negative sequence fifth- and positive sequence seventh-order voltage harmonics...... harmonics, especially low-order harmonics. This paper proposes a stator current harmonic suppression method using a sixth-order resonant controller to eliminate negative sequence fifth- and positive sequence seventh-order current harmonics. A stator current harmonic control loop is added to the conventional...

  17. Stability analysis of direct current control in current source rectifier

    DEFF Research Database (Denmark)

    Lu, Dapeng; Wang, Xiongfei; Blaabjerg, Frede

    2017-01-01

    Current source rectifier with high switching frequency has a great potential for improving the power efficiency and power density in ac-dc power conversion. This paper analyzes the stability of direct current control based on the time delay effect. Small signal model including dynamic behaviors...

  18. Optical registration of spaceborne low light remote sensing camera

    Science.gov (United States)

    Li, Chong-yang; Hao, Yan-hui; Xu, Peng-mei; Wang, Dong-jie; Ma, Li-na; Zhao, Ying-long

    2018-02-01

    For the high precision requirement of spaceborne low light remote sensing camera optical registration, optical registration of dual channel for CCD and EMCCD is achieved by the high magnification optical registration system. System integration optical registration and accuracy of optical registration scheme for spaceborne low light remote sensing camera with short focal depth and wide field of view is proposed in this paper. It also includes analysis of parallel misalignment of CCD and accuracy of optical registration. Actual registration results show that imaging clearly, MTF and accuracy of optical registration meet requirements, it provide important guarantee to get high quality image data in orbit.

  19. Registrering af postoperative sårkomplikationer på en karkirurgisk afdeling

    DEFF Research Database (Denmark)

    Jensen, Leif Panduro; Lorentzen, J E; Schroeder, T V

    1991-01-01

    During the period 1 March 1987 to 31 December 1988, current registration of all vascular surgical operations in the Department of Vascular Surgery RK, Rigshospitalet, was undertaken employing a PC-based programme (DANOP-DATA). A total of 1,898 primary vascular surgical operations were performed...

  20. Skull registration for prone patient position using tracked ultrasound

    Science.gov (United States)

    Underwood, Grace; Ungi, Tamas; Baum, Zachary; Lasso, Andras; Kronreif, Gernot; Fichtinger, Gabor

    2017-03-01

    PURPOSE: Tracked navigation has become prevalent in neurosurgery. Problems with registration of a patient and a preoperative image arise when the patient is in a prone position. Surfaces accessible to optical tracking on the back of the head are unreliable for registration. We investigated the accuracy of surface-based registration using points accessible through tracked ultrasound. Using ultrasound allows access to bone surfaces that are not available through optical tracking. Tracked ultrasound could eliminate the need to work (i) under the table for registration and (ii) adjust the tracker between surgery and registration. In addition, tracked ultrasound could provide a non-invasive method in comparison to an alternative method of registration involving screw implantation. METHODS: A phantom study was performed to test the feasibility of tracked ultrasound for registration. An initial registration was performed to partially align the pre-operative computer tomography data and skull phantom. The initial registration was performed by an anatomical landmark registration. Surface points accessible by tracked ultrasound were collected and used to perform an Iterative Closest Point Algorithm. RESULTS: When the surface registration was compared to a ground truth landmark registration, the average TRE was found to be 1.6+/-0.1mm and the average distance of points off the skull surface was 0.6+/-0.1mm. CONCLUSION: The use of tracked ultrasound is feasible for registration of patients in prone position and eliminates the need to perform registration under the table. The translational component of error found was minimal. Therefore, the amount of TRE in registration is due to a rotational component of error.

  1. Progressive attenuation fields: Fast 2D-3D image registration without precomputation

    International Nuclear Information System (INIS)

    Rohlfing, Torsten; Russakoff, Daniel B.; Denzler, Joachim; Mori, Kensaku; Maurer, Calvin R. Jr.

    2005-01-01

    Computation of digitally reconstructed radiograph (DRR) images is the rate-limiting step in most current intensity-based algorithms for the registration of three-dimensional (3D) images to two-dimensional (2D) projection images. This paper introduces and evaluates the progressive attenuation field (PAF), which is a new method to speed up DRR computation. A PAF is closely related to an attenuation field (AF). A major difference is that a PAF is constructed on the fly as the registration proceeds; it does not require any precomputation time, nor does it make any prior assumptions of the patient pose or limit the permissible range of patient motion. A PAF effectively acts as a cache memory for projection values once they are computed, rather than as a lookup table for precomputed projections like standard AFs. We use a cylindrical attenuation field parametrization, which is better suited for many medical applications of 2D-3D registration than the usual two-plane parametrization. The computed attenuation values are stored in a hash table for time-efficient storage and access. Using clinical gold-standard spine image data sets from five patients, we demonstrate consistent speedups of intensity-based 2D-3D image registration using PAF DRRs by a factor of 10 over conventional ray casting DRRs with no decrease of registration accuracy or robustness

  2. Non-rigid CT/CBCT to CBCT registration for online external beam radiotherapy guidance

    Science.gov (United States)

    Zachiu, Cornel; de Senneville, Baudouin Denis; Tijssen, Rob H. N.; Kotte, Alexis N. T. J.; Houweling, Antonetta C.; Kerkmeijer, Linda G. W.; Lagendijk, Jan J. W.; Moonen, Chrit T. W.; Ries, Mario

    2018-01-01

    Image-guided external beam radiotherapy (EBRT) allows radiation dose deposition with a high degree of accuracy and precision. Guidance is usually achieved by estimating the displacements, via image registration, between cone beam computed tomography (CBCT) and computed tomography (CT) images acquired at different stages of the therapy. The resulting displacements are then used to reposition the patient such that the location of the tumor at the time of treatment matches its position during planning. Moreover, ongoing research aims to use CBCT-CT image registration for online plan adaptation. However, CBCT images are usually acquired using a small number of x-ray projections and/or low beam intensities. This often leads to the images being subject to low contrast, low signal-to-noise ratio and artifacts, which ends-up hampering the image registration process. Previous studies addressed this by integrating additional image processing steps into the registration procedure. However, these steps are usually designed for particular image acquisition schemes, therefore limiting their use on a case-by-case basis. In the current study we address CT to CBCT and CBCT to CBCT registration by the means of the recently proposed EVolution registration algorithm. Contrary to previous approaches, EVolution does not require the integration of additional image processing steps in the registration scheme. Moreover, the algorithm requires a low number of input parameters, is easily parallelizable and provides an elastic deformation on a point-by-point basis. Results have shown that relative to a pure CT-based registration, the intrinsic artifacts present in typical CBCT images only have a sub-millimeter impact on the accuracy and precision of the estimated deformation. In addition, the algorithm has low computational requirements, which are compatible with online image-based guidance of EBRT treatments.

  3. Image registration in the brain: a test of clinical accuracy

    International Nuclear Information System (INIS)

    Rosenman, Julian; Miller, Elizabeth P.; Rinker, Lillian; Mukherji, Suresh; Tracton, Gregg; Cullip, Tim J.; Muller, Keith E.; DeLuca, Marla C.; Major, Stacey A.; Sailer, Scott; Varia, Mahesh

    1997-01-01

    Purpose/Objective: Accurate localization of tumor and normal structures is a critical step in the radiation treatment planning processes and has direct implications for tumor control success as well as normal tissue morbidity. We conducted a study to determine the accuracy of transferring tumor information from diagnostic images to the simulation films and planning CT with conventional methods using the best clinical judgment and compared that to tumor localization using 3D registration software. Materials and Methods: We measured the accuracy with which experienced clinicians could localize tumor volume from diagnostic images to either simulation films or a planning CT, with and without 3D registration software. To obtain absolute registration truth we used the method of identical pairs wherein a CT data set was duplicated and one copy resliced along a different plane than the original while maintaining the exact mathematical transformation between them. A tumor was then added to the resliced CT which became the surrogate diagnostic image. Because we were concerned that a CT/CT pair might be too easy to register, a simulated MR made by re-colorizing the resliced CT (to become a facsimile MR or fMR) was also used as a surrogate diagnostic image. Finally we studied the registration accuracy when a CT/(real)MR pair was used. The registration in this case could not be guaranteed to be exact, but the studies were obtained under carefully controlled conditions and were registered from bony landmarks using commercial radiosurgery software. A team of experts then placed the tumor from the resliced CT, fMR, or real MR to an AP and lateral 'isocenter simulation film' (a digitally reconstructed radiograph made from the unmarked CT) and to the 'planning CT' - also the unmarked CT. A registration of the data sets (CT/CT, CT/fMR and CT/MR) was also done using our 3D registration software. A total of thirty-six tasks on four subjects were performed. Four analyses (each with

  4. 78 FR 46373 - Manufacturer of Controlled Substances; Notice of Registration; Johnson Matthey Pharmaceutical...

    Science.gov (United States)

    2013-07-31

    ...; Notice of Registration; Johnson Matthey Pharmaceutical Materials, Inc. By Notice dated March 20, 2013, and published in the Federal Register on March 28, 2013, 78 FR 19017, Johnson Matthey Pharmaceutical Materials, Inc., Pharmaceutical Services, 25 Patton Road, Devens, Massachusetts 01434, made application by...

  5. 78 FR 23503 - Hazardous Materials; Temporary Reduction of Registration Fees

    Science.gov (United States)

    2013-04-19

    ... those shipments, availability of current emergency response plans, etc.). Training at more advanced... fees will be applied to any registrations paid in advance at the higher levels in effect at the time of... taxation under 26 U.S.C. 501(a). (3) Other than a small business or not-for-profit organization. Each...

  6. Solid Mesh Registration for Radiotherapy Treatment Planning

    DEFF Research Database (Denmark)

    Noe, Karsten Østergaard; Sørensen, Thomas Sangild

    2010-01-01

    We present an algorithm for solid organ registration of pre-segmented data represented as tetrahedral meshes. Registration of the organ surface is driven by force terms based on a distance field representation of the source and reference shapes. Registration of internal morphology is achieved usi...

  7. Improved image registration by sparse patch-based deformation estimation.

    Science.gov (United States)

    Kim, Minjeong; Wu, Guorong; Wang, Qian; Lee, Seong-Whan; Shen, Dinggang

    2015-01-15

    employ thin-plate splines (TPS) to interpolate a dense initial deformation field by considering all key points as the control points. Thus, the conventional image registration problem becomes much easier in the sense that we only need to compute the remaining small deformation for completing the registration of the subject to the template. Experimental results on both simulated and real data show that the registration performance can be significantly improved after integrating our patch-based deformation prediction framework into the existing registration algorithms. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. [Ideas about registration for sodium hyaluronate facial derma fillers].

    Science.gov (United States)

    Zhao, Peng; Shi, Xinli; Liu, Wenbo; Lu, Hong

    2012-09-01

    To review the registration and technical data for sodium hyaluronate facial derma fillers. Recent literature concerning registration for sodium hyaluronate facial derma fillers was reviewed and analyzed. The aspects on registration for sodium hyaluronate facial derma fillers include nominating the product, dividing registration unit, filling in a registration application form, preparing the technical data, developing the standard, and developing a registration specification. The main difficulty in registration is how to prepare the research data of that product, so the manufacturers need to enhance their basic research ability and work out a scientific technique routing which could ensure the safety and effectiveness of the product, also help to set up the supportive documents to medical device registration.

  9. Pro Forma Registration of Companies

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2010-01-01

    The article analyses the view taken by Community law on companies' pro forma registration in another EU or EEA country. Community law recognises pro forma registration under company law, i.e. a brass plate is sufficient, whereas it does not recognise pro forma registration under tax law, i.......e. a brass plate is not sufficient. The article provides reasons for the differential treatment of the two contexts and clarifies the difference on the basis of the Hubbard criterion, in which it was ruled that the effectiveness of Community law cannot vary according to the various branches of national law....

  10. Quality of registration for clinical trials published in emergency medicine journals.

    Science.gov (United States)

    Jones, Christopher W; Platts-Mills, Timothy F

    2012-10-01

    In 2005, the International Committee of Medical Journal Editors established clinical trial registration as a requirement for articles submitted to member journals, with the goal of improving the transparency of clinical research. The objective of this study is to characterize the registration of clinical trials published in emergency medicine journals. Randomized trials involving human subjects and published between June 1, 2008, and May 31, 2011 in the 5 emergency medicine journals with the highest impact factors were included. We assessed the clarity of registered primary outcomes, timing of registration relative to patient enrollment, and consistency between registered and published outcomes. Of the 123 trials included, registry entries were identified for 57 (46%). Of the 57 registered studies, 45 (79%) were registered after the initiation of subject enrollment, 9 (16%) had registered outcomes that were unclear, and 26 (46%) had discrepancies between registered and published outcomes. Only 5 studies were registered before patient enrollment with a clear primary outcome that was consistent with the published primary outcome. Annals of Emergency Medicine was the only journal in which the majority of trials were registered. Current compliance with clinical trial registration guidelines is poor among trials published in emergency medicine journals. Copyright © 2012. Published by Mosby, Inc.

  11. Lung tumor reproducibility with active breath control (ABC) in image-guided radiotherapy based on cone-beam computed tomography with two registration methods

    International Nuclear Information System (INIS)

    Wang Xin; Zhong Renming; Bai Sen; Xu Qingfeng; Zhao Yaqin; Wang Jin; Jiang Xiaoqin; Shen Yali; Xu Feng; Wei Yuquan

    2011-01-01

    Purpose: To study the inter- and intrafraction tumor reproducibility with active breath control (ABC) utilizing cone-beam computed tomography (CBCT), and compare validity of registration with two different regions of interest (ROI). Methods and materials: Thirty-one lung tumors in 19 patients received conventional or stereotactic body radiotherapy with ABC. During each treatment, patients had three CBCT scanned before and after online position correction and after treatment. These CBCT images were aligned to the planning CT using the gray scale registration of tumor and bony registration of the thorax, and tumor position uncertainties were then determined. Results: The interfraction systematic and random translation errors in the left-right (LR), superior-inferior (SI) and anterior-posterior (AP) directions were 3.6, 4.8, and 2.9 mm; 2.5, 4.5, and 3.5 mm, respectively, with gray scale alignment; 1.9, 4.3, 2.0 mm and 2.5, 4.4, 2.9 mm, respectively, with bony alignment. The interfraction systematic and random rotation errors with gray scale and bony alignment groups ranged from 1.4 o to 3.0 o and 0.8 o to 2.3 o , respectively. The intrafraction systematic and random errors with gray scale registration in LR, SI, AP directions were 0.9, 2.0, 1.8 mm and 1.5, 1.7, 2.9 mm, respectively, for translation; 1.5 o , 0.9 o , 1.0 o and 1.2 o , 2.2 o , 1.8 o , respectively, for rotation. The translational errors in SI direction with bony alignment were significantly larger than that of gray scale (p < 0.05). Conclusions: With CBCT guided online correction the interfraction positioning errors can be markedly reduced. The intrafraction errors were not diminished by the use of ABC. Rotation errors were not very remarkable both inter- and intrafraction. Gray scale alignment of tumor may provide a better registration in SI direction.

  12. Fiducial-based registration with a touchable region model.

    Science.gov (United States)

    Kim, Sungmin; Kazanzides, Peter

    2017-02-01

    Image-guided surgery requires registration between an image coordinate system and an intraoperative coordinate system that is typically referenced to a tracking device. In fiducial-based registration methods, this is achieved by localizing points (fiducials) in each coordinate system. Often, both localizations are performed manually, first by picking a fiducial point in the image and then by using a hand-held tracked pointer to physically touch the corresponding fiducial on the patient. These manual procedures introduce localization error that is user-dependent and can significantly decrease registration accuracy. Thus, there is a need for a registration method that is tolerant of imprecise fiducial localization in the preoperative and intraoperative phases. We propose the iterative closest touchable point (ICTP) registration framework, which uses model-based localization and a touchable region model. This method consists of three stages: (1) fiducial marker localization in image space, using a fiducial marker model, (2) initial registration with paired-point registration, and (3) fine registration based on the iterative closest point method. We perform phantom experiments with a fiducial marker design that is commonly used in neurosurgery. The results demonstrate that ICTP can provide accuracy improvements compared to the standard paired-point registration method that is widely used for surgical navigation and surgical robot systems, especially in cases where the surgeon introduces large localization errors. The results demonstrate that the proposed method can reduce the effect of the surgeon's localization performance on the accuracy of registration, thereby producing more consistent and less user-dependent registration outcomes.

  13. 40 CFR 152.115 - Conditions of registration.

    Science.gov (United States)

    2010-07-01

    ... specify any provisions for sale and distribution of existing stocks of the pesticide product. (3) The... PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Agency Review of Applications § 152.115 Conditions of registration. (a) Substantially similar products and new uses. Each registration issued under § 152.113 shall...

  14. The whereabouts of Migrants : A comparison of Dutch migrant registration systems

    NARCIS (Netherlands)

    van Faassen, M.

    2017-01-01

    The whereabouts of migrants: a comparison of Dutch migrant registration systems. Today, one way of visualising the current refugee and migrant crisis on the outer borders of Europe is by showing a bottleneck in the processing of migrant flows: large groups of people waiting endlessly for their

  15. 78 FR 16298 - Manufacturer of Controlled Substances, Notice of Registration; Johnson Matthey, Inc.

    Science.gov (United States)

    2013-03-14

    ... interest at this time. DEA has investigated Johnson Matthey, Inc., to ensure that the company's..., Notice of Registration; Johnson Matthey, Inc. By Notice dated November 5, 2012, and published in the Federal Register on November 13, 2012, 77 FR 67676, Johnson Matthey, Inc., Custom Pharmaceuticals...

  16. Disturbance observer based current controller for vector controlled IM drives

    DEFF Research Database (Denmark)

    Teodorescu, Remus; Dal, Mehmet

    2008-01-01

    induction motor (IM) drives. The control design, based on synchronously rotating d-q frame model of the machine, has a simple structure that combines the proportional portion of a conventional PI control and output of the observer. The observer is predicted to estimate the disturbances caused by parameters...... coupling effects and increase robustness against parameters change without requiring any other compensation strategies. The experimental implementation results are provided to demonstrate validity and performance of the proposed control scheme.......In order to increase the accuracy of the current control loop, usually, well known parameter compensation and/or cross decoupling techniques are employed for advanced ac drives. In this paper, instead of using these techniques an observer-based current controller is proposed for vector controlled...

  17. Vertical dimensional stability and rigidity of occlusal registration materials.

    Science.gov (United States)

    Walker, Mary P; Wu, Edis; Heckman, M Elizabeth; Alderman, Nicholas

    2009-01-01

    Dimensionally accurate occlusal registration records are essential for restorative dentistry; moreover, since records are not used immediately or may be used more than once, the registration material should exhibit accuracy over time (a concept known as dimensional stability). It has been speculated that materials with increased hardness or rigidity should produce more accurate registration records due to an increased resistance to distortion. This study compared the rigidity and associated dimensional accuracy of a recently marketed bisacrylic occlusal registration material and a vinyl polysiloxane (VPS). Maxillary and mandibular typodont arches were mounted on a plasterless articulator from which teeth No. 3, 13, and 15 had been removed to simulate edentulous spaces. After preparing teeth No. 2, 4, 12, and 14 as bridge abutments, the remaining teeth were equilibrated selectively to produce even anterior contact. Four digital photographs were taken to make vertical interarch measurements at four locations (teeth No. 3, 7, 10, and 14). Following initial photos (controls), 10 interocclusal records were made using each registration material, with material placed only in the segments in which teeth were prepared. The records were used for mounting the maxillary arch against the mandibular arch after 48, 72, and 120 hours. There were significant effects on vertical dimensional change related to arch location, material, and mounting time. Both materials demonstrated significantly larger posterior vertical openings than anterior vertical openings, while the bisacrylate produced a larger posterior opening than VPS at 48 and 72 hours and a larger anterior opening at all mounting times. There also was a significant difference in hardness/rigidity due to material and measurement time; at all measurement times, bisacrylate exhibited a significantly higher hardness number.

  18. Magnetoelectric control of spin currents

    Energy Technology Data Exchange (ETDEWEB)

    Gómez, J. E.; Vargas, J. M.; Avilés-Félix, L.; Butera, A. [Centro Atómico Bariloche, Instituto de Nanociencia y Nanotecnología (CNEA) and Conicet, 8400 Bariloche, Río Negro (Argentina)

    2016-06-13

    The ability to control the spin current injection has been explored on a hybrid magnetoelectric system consisting of a (011)-cut ferroelectric lead magnesium niobate-lead titanate (PMNT) single crystal, a ferromagnetic FePt alloy, and a metallic Pt. With this PMNT/FePt/Pt structure we have been able to control the magnetic field position or the microwave excitation frequency at which the spin pumping phenomenon between FePt and Pt occurs. We demonstrate that the magnetoelectric heterostructure operating in the L-T (longitudinal magnetized-transverse polarized) mode couples the PMNT crystal to the magnetostrictive FePt/Pt bilayer, displaying a strong magnetoelectric coefficient of ∼140 Oe cm kV{sup −1}. Our results show that this mechanism can be effectively exploited as a tunable spin current intensity emitter and open the possibility to create an oscillating or a bistable switch to effectively manipulate spin currents.

  19. 32 CFR 635.27 - Vehicle Registration System.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Vehicle Registration System. 635.27 Section 635.27 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS LAW ENFORCEMENT REPORTING Offense Reporting § 635.27 Vehicle Registration System. The Vehicle Registration System (VR...

  20. 37 CFR 1.293 - Statutory invention registration.

    Science.gov (United States)

    2010-07-01

    ... the date of publication of the statutory invention registration; (2) The required fee for filing a request for publication of a statutory invention registration as provided for in § 1.17 (n) or (o); (3) A... application. (b) Any request for publication of a statutory invention registration must include the following...

  1. 77 FR 16263 - Manufacturer of Controlled Substances, Notice of Registration; Johnson Matthey Inc.

    Science.gov (United States)

    2012-03-20

    ... the public interest at this time. DEA has investigated Johnson Matthey Inc. to ensure that the company..., Notice of Registration; Johnson Matthey Inc. By Notice dated November 18, 2011, and published in the Federal Register on November 28, 2011, 76 FR 72974, Johnson Matthey Inc., Custom Pharmaceuticals...

  2. Complexities of policy-driven pre-registration nursing curricula.

    Science.gov (United States)

    McCarthy, Jilian; Holt, Maxine

    This article discusses the challenges faced by two nurse educators when incorporating current health policy into a new pre-registration nursing curriculum, using public health and e-learning as examples. The article, which features the results of preliminary work from the authors' doctoral studies, includes summaries of students' discourses about e-learning and public health and how these subject areas are perceived by learners. Practical solutions to the challenges encountered are suggested.

  3. Registration of the cancer

    International Nuclear Information System (INIS)

    Morales, F.; Campos, X.

    2002-01-01

    A database for the registration of the cancer was designed in ambient access, of the Microsoft Office, to take the registrations at national level. With this database the statistics will be obtained about the incidence of the cancer in the population, evaluation of the sanitary services of prevention, diagnose and treatment of the illness, etc. The used codes are according to the listings of code of the Ministry of Health (MINSA) and OPS

  4. 46 CFR 401.220 - Registration of pilots.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Registration of pilots. 401.220 Section 401.220 Shipping... Registration of Pilots § 401.220 Registration of pilots. (a) The Director shall determine the number of pilots... waters of the Great Lakes and to provide for equitable participation of United States Registered Pilots...

  5. A Novel Sliding Mode Control Technique for Indirect Current Controlled Active Power Filter

    Directory of Open Access Journals (Sweden)

    Juntao Fei

    2012-01-01

    Full Text Available A novel sliding mode control (SMC method for indirect current controlled three-phase parallel active power filter is presented in this paper. There are two designed closed loops in the system: one is the DC voltage controlling loop and the other is the reference current tracking loop. The first loop with a PI regulator is used to control the DC voltage approximating to the given voltage of capacitor, and the output of PI regulator through a low-pass filter is applied as the input of the power supply reference currents. The second loop implements the tracking of the reference currents using integral sliding mode controller, which can improve the harmonic treating performance. Compared with the direct current control technique, it is convenient to be implemented with digital signal processing system because of simpler system structure and better harmonic treating property. Simulation results verify that the generated reference currents have the same amplitude with the load currents, demonstrating the superior harmonic compensating effects with the proposed shunt active power filter compared with the hysteresis method.

  6. Registration of 3-dimensional facial photographs for clinical use.

    Science.gov (United States)

    Maal, Thomas J J; van Loon, Bram; Plooij, Joanneke M; Rangel, Frits; Ettema, Anke M; Borstlap, Wilfred A; Bergé, Stefaan J

    2010-10-01

    To objectively evaluate treatment outcomes in oral and maxillofacial surgery, pre- and post-treatment 3-dimensional (3D) photographs of the patient's face can be registered. For clinical use, it is of great importance that this registration process is accurate (photographs were captured at 3 different times: baseline (T(0)), after 1 minute (T(1)), and 3 weeks later (T(2)). Furthermore, a 3D photograph of the volunteer laughing (T(L)) was acquired to investigate the effect of facial expression. Two different registration methods were used to register the photographs acquired at all different times: surface-based registration and reference-based registration. Within the surface-based registration, 2 different software packages (Maxilim [Medicim NV, Mechelen, Belgium] and 3dMD Patient [3dMD LLC, Atlanta, GA]) were used to register the 3D photographs acquired at the various times. The surface-based registration process was repeated with the preprocessed photographs. Reference-based registration (Maxilim) was performed twice by 2 observers investigating the inter- and intraobserver error. The mean registration errors are small for the 3D photographs at rest (0.39 mm for T(0)-T(1) and 0.52 mm for T(0)-T(2)). The mean registration error increased to 1.2 mm for the registration between the 3D photographs acquired at T(0) and T(L). The mean registration error for the reference-based method was 1.0 mm for T(0)-T(1), 1.1 mm for T(0)-T(2), and 1.5 mm for T(0) and T(L). The mean registration errors for the preprocessed photographs were even smaller (0.30 mm for T(0)-T(1), 0.42 mm for T(0)-T(2), and 1.2 mm for T(0) and T(L)). Furthermore, a strong correlation between the results of both software packages used for surface-based registration was found. The intra- and interobserver error for the reference-based registration method was found to be 1.2 and 1.0 mm, respectively. Surface-based registration is an accurate method to compare 3D photographs of the same individual at

  7. 78 FR 64020 - Manufacturer of Controlled Substances, Notice of Registration, Siegfried USA, LLC

    Science.gov (United States)

    2013-10-25

    ..., Notice of Registration, Siegfried USA, LLC The Notice dated July 23, 2013, and published in the Federal Register on August 1, 2013, 78 FR 46613, page 18338, Siegfried (USA), LLC., 33 Industrial Park Road...), and Poppy Straw Concentrate (9670). On August 6, 2013, Siegfried (USA), LLC., subsequently withdrew...

  8. Automated registration of multispectral MR vessel wall images of the carotid artery

    Energy Technology Data Exchange (ETDEWEB)

    Klooster, R. van ' t; Staring, M.; Reiber, J. H. C.; Lelieveldt, B. P. F.; Geest, R. J. van der, E-mail: rvdgeest@lumc.nl [Department of Radiology, Division of Image Processing, Leiden University Medical Center, 2300 RC Leiden (Netherlands); Klein, S. [Department of Radiology and Department of Medical Informatics, Biomedical Imaging Group Rotterdam, Erasmus MC, Rotterdam 3015 GE (Netherlands); Kwee, R. M.; Kooi, M. E. [Department of Radiology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht 6202 AZ (Netherlands)

    2013-12-15

    moving image after registration. Results: The average required manual translation per image slice was 1.33 mm. Translations were larger as the patient was longer inside the scanner. Manual alignment took 187.5 s per patient resulting in a mean surface distance of 0.271 ± 0.127 mm. After minimal user interaction to generate the mask in the fixed image, the remaining sequences are automatically registered with a computation time of 52.0 s per patient. The optimal registration strategy used a circular mask with a diameter of 10 mm, a 3D B-spline transformation model with a control point spacing of 15 mm, mutual information as image similarity metric, and the precontrast T1W TSE as fixed image. A mean surface distance of 0.288 ± 0.128 mm was obtained with these settings, which is very close to the accuracy of the manual alignment procedure. The exact registration parameters and software were made publicly available. Conclusions: An automated registration method was developed and optimized, only needing two mouse clicks to mark the start and end point of the artery. Validation on a large group of patients showed that automated image registration has similar accuracy as the manual alignment procedure, substantially reducing the amount of user interactions needed, and is multiple times faster. In conclusion, the authors believe that the proposed automated method can replace the current manual procedure, thereby reducing the time to analyze the images.

  9. Automated registration of multispectral MR vessel wall images of the carotid artery

    International Nuclear Information System (INIS)

    Klooster, R. van 't; Staring, M.; Reiber, J. H. C.; Lelieveldt, B. P. F.; Geest, R. J. van der; Klein, S.; Kwee, R. M.; Kooi, M. E.

    2013-01-01

    moving image after registration. Results: The average required manual translation per image slice was 1.33 mm. Translations were larger as the patient was longer inside the scanner. Manual alignment took 187.5 s per patient resulting in a mean surface distance of 0.271 ± 0.127 mm. After minimal user interaction to generate the mask in the fixed image, the remaining sequences are automatically registered with a computation time of 52.0 s per patient. The optimal registration strategy used a circular mask with a diameter of 10 mm, a 3D B-spline transformation model with a control point spacing of 15 mm, mutual information as image similarity metric, and the precontrast T1W TSE as fixed image. A mean surface distance of 0.288 ± 0.128 mm was obtained with these settings, which is very close to the accuracy of the manual alignment procedure. The exact registration parameters and software were made publicly available. Conclusions: An automated registration method was developed and optimized, only needing two mouse clicks to mark the start and end point of the artery. Validation on a large group of patients showed that automated image registration has similar accuracy as the manual alignment procedure, substantially reducing the amount of user interactions needed, and is multiple times faster. In conclusion, the authors believe that the proposed automated method can replace the current manual procedure, thereby reducing the time to analyze the images

  10. Central research registration at Technical University of Denmark (DTU)

    DEFF Research Database (Denmark)

    Sand, Ane Ahrenkiel

    Some five years ago, DTU switched from decentralized research registration, where researchers entered their publications into the DTU research repository themselves to centralized research registration, whereby library staff upload academic publications to the repository on behalf...... up the registration team, the configuration of the repository platform (Pure), the registration workflow and last but not least the results since DTU switched to centralized research registration....

  11. Central Research Registration at Technical University of Denmark (DTU)

    DEFF Research Database (Denmark)

    Sand, Ane Ahrenkiel

    Some five years ago, DTU switched from decentralized research registration, where researchers entered their publications into the DTU research repository themselves to centralized research registration, whereby library staff upload academic publications to the repository on behalf...... up the registration team, the configuration of the repository platform (Pure), the registration workflow and last but not least the results since DTU switched to centralized research registration....

  12. Fuels Registration, Reporting, and Compliance Help

    Science.gov (United States)

    Information about the requirements for registration and health effects testing of new fuels or fuel additives and mandatory registration for fuels reporting and about mandatory reporting forms for parties regulated under EPA fuel programs.

  13. A MRI-CT prostate registration using sparse representation technique

    Science.gov (United States)

    Yang, Xiaofeng; Jani, Ashesh B.; Rossi, Peter J.; Mao, Hui; Curran, Walter J.; Liu, Tian

    2016-03-01

    technique was validated with a clinical study of 10 patients. The accuracy of our approach was assessed using some identified landmarks in both MRI and CT images. Our proposed registration was compared with the current free-form-deformation (FFD)-based registration method. The accuracy of the proposed method was significantly higher than the commonly used FFD-based registration utilizing normalized mutual information (NMI). Conclusions: We have developed a new prostate MR-CT registration approach based on patch-deformation dictionary, demonstrated its clinical feasibility, and validated its accuracy with some identified landmarks. The proposed registration method may provide an accurate and robust means of estimating prostate-gland deformation between MRI and CT scans, and is therefore well-suited for a number of MR-targeted CT-based prostate radiotherapy.

  14. The cadastral registration of the property right

    Directory of Open Access Journals (Sweden)

    D.-G. IONAȘ

    2017-12-01

    Full Text Available Real rights are subjective patrimonial rights which provide the holder with the right to directly exercise certain prerogatives over a determined good. Real rights over immobile goods, registered in the cadastral register are called tabular rights. Cadastral registration is that certain form of registration by which a real right over an immobile good is acquired, changed or ended, from the time de registration request is filed. At this time, registration in the cadastral register provides the opposability effect, as the constitutive effect is suspended until the cadastral works are finalized and new cadastral registers are created for each administrative unit.

  15. TU-A-19A-01: Image Registration I: Deformable Image Registration, Contour Propagation and Dose Mapping: 101 and 201

    Energy Technology Data Exchange (ETDEWEB)

    Kessler, M [The University of Michigan, Ann Arbor, MI (United States)

    2014-06-15

    Deformable image registration, contour propagation and dose mapping have become common, possibly essential tools for modern image-guided radiation therapy. Historically, these tools have been largely developed at academic medical centers and used in a rather limited and well controlled fashion. Today these tools are now available to the radiotherapy community at large, both as stand-alone applications and as integrated components of both treatment planning and treatment delivery systems. Unfortunately, the details of how these tools work and their limitations are not generally documented or described by the vendors that provide them. Although “it looks right”, determining that unphysical deformations may have occurred is crucial. Because of this, understanding how and when to use, and not use these tools to support everyday clinical decisions is far from straight forward. The goal of this session will be to present both the theory (basic and advanced) and practical clinical use of deformable image registration, contour propagation and dose mapping. To the extent possible, the “secret sauce” that different vendor use to produce reasonable/acceptable results will be described. A detailed explanation of the possible sources of errors and actual examples of these will be presented. Knowing the underlying principles of the process and understanding the confounding factors will help the practicing medical physicist be better able to make decisions (about making decisions) using these tools available. Learning Objectives: Understand the basic (101) and advanced (201) principles of deformable image registration, contour propagation and dose mapping data mapping. Understand the sources and impact of errors in registration and data mapping and the methods for evaluating the performance of these tools. Understand the clinical use and value of these tools, especially when used as a “black box”.

  16. Promoting deceased organ and tissue donation registration in family physician waiting rooms (RegisterNow-1 trial): study protocol for a pragmatic, stepped-wedge, cluster randomized controlled registry.

    Science.gov (United States)

    Li, Alvin H; Garg, Amit X; Prakash, Versha; Grimshaw, Jeremy M; Taljaard, Monica; Mitchell, Joanna; Matti, Danny; Linklater, Stefanie; Naylor, Kyla L; Dixon, Stephanie; Faulds, Cathy; Bevan, Rachel; Getchell, Leah; Knoll, Greg; Kim, S Joseph; Sontrop, Jessica; Bjerre, Lise M; Tong, Allison; Presseau, Justin

    2017-12-21

    There is a worldwide shortage of organs available for transplant, leading to preventable mortality associated with end-stage organ disease. While most citizens in many countries with an intent-to-donate "opt-in" system support organ donation, registration rates remain low. In Canada, most Canadians support organ donation but less than 25% in most provinces have registered their desire to donate their organs when they die. The family physician office is a promising yet underused setting in which to promote organ donor registration and address known barriers and enablers to registering for deceased organ and tissue donation. We developed a protocol to evaluate an intervention to promote registration for organ and tissue donation in family physician waiting rooms. This protocol describes a planned, stepped-wedge, cluster randomized registry trial in six family physician offices in Ontario, Canada to evaluate the effectiveness of reception staff providing patients with a pamphlet that addresses barriers and enablers to registration including a description of how to register for organ donation. An Internet-enabled tablet will also be provided in waiting rooms so that interested patients can register while waiting for their appointments. Family physicians and reception staff will be provided with training and/or materials to support any conversations about organ donation with their patients. Following a 2-week control period, the six offices will cross sequentially into the intervention arm in randomized sequence at 2-week intervals until all offices deliver the intervention. The primary outcome will be the proportion of patients visiting the office who are registered organ donors 7 days following their office visit. We will evaluate this outcome using routinely collected registry data from provincial administrative databases. A post-trial qualitative evaluation process will assess the experiences of reception staff and family physicians with the intervention and the

  17. An object-oriented framework for medical image registration, fusion, and visualization.

    Science.gov (United States)

    Zhu, Yang-Ming; Cochoff, Steven M

    2006-06-01

    An object-oriented framework for image registration, fusion, and visualization was developed based on the classic model-view-controller paradigm. The framework employs many design patterns to facilitate legacy code reuse, manage software complexity, and enhance the maintainability and portability of the framework. Three sample applications built a-top of this framework are illustrated to show the effectiveness of this framework: the first one is for volume image grouping and re-sampling, the second one is for 2D registration and fusion, and the last one is for visualization of single images as well as registered volume images.

  18. Three dimensional image alignment, registration and fusion

    International Nuclear Information System (INIS)

    Treves, S.T.; Mitchell, K.D.; Habboush, I.H.

    1998-01-01

    Combined assessment of three dimensional anatomical and functional images (SPECT, PET, MRI, CT) is useful to determine the nature and extent of lesions in many parts of the body. Physicians principally rely on their spatial sense of mentally re-orient and overlap images obtained with different imaging modalities. Objective methods that enable easy and intuitive image registration can help the physician arrive at more optimal diagnoses and better treatment decisions. This review describes a simple, intuitive and robust image registration approach developed in our laboratory. It differs from most other registration techniques in that it allows the user to incorporate all of the available information within the images in the registration process. This method takes full advantage of the ability of knowledgeable operators to achieve image registration and fusion using an intuitive interactive visual approach. It can register images accurately and quickly without the use of elaborate mathematical modeling or optimization techniques. The method provides the operator with tools to manipulate images in three dimensions, including visual feedback techniques to assess the accuracy of registration (grids, overlays, masks, and fusion of images in different colors). Its application is not limited to brain imaging and can be applied to images from any region in the body. The overall effect is a registration algorithm that is easy to implement and can achieve accuracy on the order of one pixel

  19. Sulcal set optimization for cortical surface registration.

    Science.gov (United States)

    Joshi, Anand A; Pantazis, Dimitrios; Li, Quanzheng; Damasio, Hanna; Shattuck, David W; Toga, Arthur W; Leahy, Richard M

    2010-04-15

    Flat mapping based cortical surface registration constrained by manually traced sulcal curves has been widely used for inter subject comparisons of neuroanatomical data. Even for an experienced neuroanatomist, manual sulcal tracing can be quite time consuming, with the cost increasing with the number of sulcal curves used for registration. We present a method for estimation of an optimal subset of size N(C) from N possible candidate sulcal curves that minimizes a mean squared error metric over all combinations of N(C) curves. The resulting procedure allows us to estimate a subset with a reduced number of curves to be traced as part of the registration procedure leading to optimal use of manual labeling effort for registration. To minimize the error metric we analyze the correlation structure of the errors in the sulcal curves by modeling them as a multivariate Gaussian distribution. For a given subset of sulci used as constraints in surface registration, the proposed model estimates registration error based on the correlation structure of the sulcal errors. The optimal subset of constraint curves consists of the N(C) sulci that jointly minimize the estimated error variance for the subset of unconstrained curves conditioned on the N(C) constraint curves. The optimal subsets of sulci are presented and the estimated and actual registration errors for these subsets are computed. Copyright 2009 Elsevier Inc. All rights reserved.

  20. Licensing procedures and registration of medical doctors in the European Union.

    Science.gov (United States)

    Kovacs, Eszter; Schmidt, Andrea E; Szocska, Gabor; Busse, Reinhard; McKee, Martin; Legido-Quigley, Helena

    2014-06-01

    The current proposals to update the European Union (EU) directive on professional qualifications will have potentially important implications for health professions. Yet those discussing it will struggle to find basic information on key issues such as licensing and registration of physicians in different countries. A survey was conducted among national experts in 14 EU member states, supplemented by literature and independent expert review. The questionnaire covered five components of licensing and registration: (1) definitions, (2) regulatory basis, (3) governance, (4) the process of registration and (5) flow and quantity of applications. We identify seven areas of concern: (1) the meaning of terminology, which is inconsistent; (2) the role of language assessments and the responsibility for them; (3) whether approval to practise should be lifelong or time limited, subject to periodic assessment; (4) the need for improved systems to identify those deemed no longer fit to practise in one member state; (5) the complexity of processes for graduates from non-EU/European Economic Area (EAA) countries; (6) public access to registers; and (7) transparency of systems of governance. The systems of licensing and registration of doctors in Europe have developed within specific national contexts and vary widely. This creates inevitable problems in the context of free movement of professionals and increasing mobility. © 2014 Royal College of Physicians.

  1. Automatic registration method for multisensor datasets adopted for dimensional measurements on cutting tools

    International Nuclear Information System (INIS)

    Shaw, L; Mehari, F; Weckenmann, A; Ettl, S; Häusler, G

    2013-01-01

    Multisensor systems with optical 3D sensors are frequently employed to capture complete surface information by measuring workpieces from different views. During coarse and fine registration the resulting datasets are afterward transformed into one common coordinate system. Automatic fine registration methods are well established in dimensional metrology, whereas there is a deficit in automatic coarse registration methods. The advantage of a fully automatic registration procedure is twofold: it enables a fast and contact-free alignment and further a flexible application to datasets of any kind of optical 3D sensor. In this paper, an algorithm adapted for a robust automatic coarse registration is presented. The method was originally developed for the field of object reconstruction or localization. It is based on a segmentation of planes in the datasets to calculate the transformation parameters. The rotation is defined by the normals of three corresponding segmented planes of two overlapping datasets, while the translation is calculated via the intersection point of the segmented planes. First results have shown that the translation is strongly shape dependent: 3D data of objects with non-orthogonal planar flanks cannot be registered with the current method. In the novel supplement for the algorithm, the translation is additionally calculated via the distance between centroids of corresponding segmented planes, which results in more than one option for the transformation. A newly introduced measure considering the distance between the datasets after coarse registration evaluates the best possible transformation. Results of the robust automatic registration method are presented on the example of datasets taken from a cutting tool with a fringe-projection system and a focus-variation system. The successful application in dimensional metrology is proven with evaluations of shape parameters based on the registered datasets of a calibrated workpiece. (paper)

  2. REGISTRATION OF LASER SCANNING POINT CLOUDS AND AERIAL IMAGES USING EITHER ARTIFICIAL OR NATURAL TIE FEATURES

    Directory of Open Access Journals (Sweden)

    P. Rönnholm

    2012-07-01

    Full Text Available Integration of laser scanning data and photographs is an excellent combination regarding both redundancy and complementary. Applications of integration vary from sensor and data calibration to advanced classification and scene understanding. In this research, only airborne laser scanning and aerial images are considered. Currently, the initial registration is solved using direct orientation sensors GPS and inertial measurements. However, the accuracy is not usually sufficient for reliable integration of data sets, and thus the initial registration needs to be improved. A registration of data from different sources requires searching and measuring of accurate tie features. Usually, points, lines or planes are preferred as tie features. Therefore, the majority of resent methods rely highly on artificial objects, such as buildings, targets or road paintings. However, in many areas no such objects are available. For example in forestry areas, it would be advantageous to be able to improve registration between laser data and images without making additional ground measurements. Therefore, there is a need to solve registration using only natural features, such as vegetation and ground surfaces. Using vegetation as tie features is challenging, because the shape and even location of vegetation can change because of wind, for example. The aim of this article was to compare registration accuracies derived by using either artificial or natural tie features. The test area included urban objects as well as trees and other vegetation. In this area, two registrations were performed, firstly, using mainly built objects and, secondly, using only vegetation and ground surface. The registrations were solved applying the interactive orientation method. As a result, using artificial tie features leaded to a successful registration in all directions of the coordinate system axes. In the case of using natural tie features, however, the detection of correct heights was

  3. Analysis of Point Based Image Registration Errors With Applications in Single Molecule Microscopy.

    Science.gov (United States)

    Cohen, E A K; Ober, R J

    2013-12-15

    We present an asymptotic treatment of errors involved in point-based image registration where control point (CP) localization is subject to heteroscedastic noise; a suitable model for image registration in fluorescence microscopy. Assuming an affine transform, CPs are used to solve a multivariate regression problem. With measurement errors existing for both sets of CPs this is an errors-in-variable problem and linear least squares is inappropriate; the correct method being generalized least squares. To allow for point dependent errors the equivalence of a generalized maximum likelihood and heteroscedastic generalized least squares model is achieved allowing previously published asymptotic results to be extended to image registration. For a particularly useful model of heteroscedastic noise where covariance matrices are scalar multiples of a known matrix (including the case where covariance matrices are multiples of the identity) we provide closed form solutions to estimators and derive their distribution. We consider the target registration error (TRE) and define a new measure called the localization registration error (LRE) believed to be useful, especially in microscopy registration experiments. Assuming Gaussianity of the CP localization errors, it is shown that the asymptotic distribution for the TRE and LRE are themselves Gaussian and the parameterized distributions are derived. Results are successfully applied to registration in single molecule microscopy to derive the key dependence of the TRE and LRE variance on the number of CPs and their associated photon counts. Simulations show asymptotic results are robust for low CP numbers and non-Gaussianity. The method presented here is shown to outperform GLS on real imaging data.

  4. 21 CFR 207.25 - Information required in registration and drug listing.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Information required in registration and drug listing. 207.25 Section 207.25 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... manufactured by a registered blood bank, a copy of all current labeling (except that only one representative...

  5. Improving oncoplastic breast tumor bed localization for radiotherapy planning using image registration algorithms

    Science.gov (United States)

    Wodzinski, Marek; Skalski, Andrzej; Ciepiela, Izabela; Kuszewski, Tomasz; Kedzierawski, Piotr; Gajda, Janusz

    2018-02-01

    Knowledge about tumor bed localization and its shape analysis is a crucial factor for preventing irradiation of healthy tissues during supportive radiotherapy and as a result, cancer recurrence. The localization process is especially hard for tumors placed nearby soft tissues, which undergo complex, nonrigid deformations. Among them, breast cancer can be considered as the most representative example. A natural approach to improving tumor bed localization is the use of image registration algorithms. However, this involves two unusual aspects which are not common in typical medical image registration: the real deformation field is discontinuous, and there is no direct correspondence between the cancer and its bed in the source and the target 3D images respectively. The tumor no longer exists during radiotherapy planning. Therefore, a traditional evaluation approach based on known, smooth deformations and target registration error are not directly applicable. In this work, we propose alternative artificial deformations which model the tumor bed creation process. We perform a comprehensive evaluation of the most commonly used deformable registration algorithms: B-Splines free form deformations (B-Splines FFD), different variants of the Demons and TV-L1 optical flow. The evaluation procedure includes quantitative assessment of the dedicated artificial deformations, target registration error calculation, 3D contour propagation and medical experts visual judgment. The results demonstrate that the currently, practically applied image registration (rigid registration and B-Splines FFD) are not able to correctly reconstruct discontinuous deformation fields. We show that the symmetric Demons provide the most accurate soft tissues alignment in terms of the ability to reconstruct the deformation field, target registration error and relative tumor volume change, while B-Splines FFD and TV-L1 optical flow are not an appropriate choice for the breast tumor bed localization problem

  6. Line-Enhanced Deformable Registration of Pulmonary Computed Tomography Images Before and After Radiation Therapy With Radiation-Induced Fibrosis

    Science.gov (United States)

    Sensakovic, William F.; Maxim, Peter; Diehn, Maximilian; Loo, Billy W.; Xing, Lei

    2018-01-01

    Purpose: The deformable registration of pulmonary computed tomography images before and after radiation therapy is challenging due to anatomic changes from radiation fibrosis. We hypothesize that a line-enhanced registration algorithm can reduce landmark error over the entire lung, including the irradiated regions, when compared to an intensity-based deformable registration algorithm. Materials: Two intensity-based B-spline deformable registration algorithms of pre-radiation therapy and post-radiation therapy images were compared. The first was a control intensity–based algorithm that utilized computed tomography images without modification. The second was a line enhancement algorithm that incorporated a Hessian-based line enhancement filter prior to deformable image registration. Registrations were evaluated based on the landmark error between user-identified landmark pairs and the overlap ratio. Results: Twenty-one patients with pre-radiation therapy and post-radiation therapy scans were included. The median time interval between scans was 1.2 years (range: 0.3-3.3 years). Median landmark errors for the line enhancement algorithm were significantly lower than those for the control algorithm over the entire lung (1.67 vs 1.83 mm; P 5 Gy (2.25 vs 3.31; P 5 Gy dose interval demonstrated a significant inverse relationship with post-radiation therapy fibrosis enhancement after line enhancement filtration (Pearson correlation coefficient = −0.48; P = .03). Conclusion: The line enhancement registration algorithm is a promising method for registering images before and after radiation therapy. PMID:29343206

  7. Subspace-Based Holistic Registration for Low-Resolution Facial Images

    Directory of Open Access Journals (Sweden)

    Boom BJ

    2010-01-01

    Full Text Available Subspace-based holistic registration is introduced as an alternative to landmark-based face registration, which has a poor performance on low-resolution images, as obtained in camera surveillance applications. The proposed registration method finds the alignment by maximizing the similarity score between a probe and a gallery image. We use a novel probabilistic framework for both user-independent as well as user-specific face registration. The similarity is calculated using the probability that the face image is correctly aligned in a face subspace, but additionally we take the probability into account that the face is misaligned based on the residual error in the dimensions perpendicular to the face subspace. We perform extensive experiments on the FRGCv2 database to evaluate the impact that the face registration methods have on face recognition. Subspace-based holistic registration on low-resolution images can improve face recognition in comparison with landmark-based registration on high-resolution images. The performance of the tested face recognition methods after subspace-based holistic registration on a low-resolution version of the FRGC database is similar to that after manual registration.

  8. 48 CFR 52.204-7 - Central Contractor Registration.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Central Contractor....204-7 Central Contractor Registration. As prescribed in 4.1105, use the following clause: Central Contractor Registration (APR 2008) (a) Definitions. As used in this clause— Central Contractor Registration...

  9. Discrete-Time LPV Current Control of an Induction Motor

    DEFF Research Database (Denmark)

    Bendtsen, Jan Dimon; Trangbæk, Klaus

    2001-01-01

    In this paper we apply a new method for gain-scheduled output feedback control of nonlinear systems to current control of an induction motor. The method relies on recently developed controller synthesis results for linear parameter-varying (LPV) systems, where the controller synthesis is formulated...... without further complications. The synthesis method is applied to the model, yielding an LPV discrete-time controller. Finally, the efficiency of the control scheme is validated via simulations as well as experimentally on the actual induction motor, both in open-loop current control and when an outer...... speed control loop is closed around the current loop...

  10. Discrete-Time LPV Current Control of an Induction Motor

    DEFF Research Database (Denmark)

    Bendtsen, Jan Dimon; Trangbæk, Klaus

    2003-01-01

    In this paper we apply a new method for gain-scheduled output feedback control of nonlinear systems to current control of an induction motor. The method relies on recently developed controller synthesis results for linear parameter-varying (LPV) systems, where the controller synthesis is formulated...... further complications. The synthesis method is applied to the model, yielding an LPV discrete-time controller. Finally, the efficiency of the control scheme is validated via simulations as well as on the actual induction motor, both in open-loop current control and when an outer speed control loop...... is closed around the current loop....

  11. The Pose Estimation of Mobile Robot Based on Improved Point Cloud Registration

    Directory of Open Access Journals (Sweden)

    Yanzi Miao

    2016-03-01

    Full Text Available Due to GPS restrictions, an inertial sensor is usually used to estimate the location of indoor mobile robots. However, it is difficult to achieve high-accuracy localization and control by inertial sensors alone. In this paper, a new method is proposed to estimate an indoor mobile robot pose with six degrees of freedom based on an improved 3D-Normal Distributions Transform algorithm (3D-NDT. First, point cloud data are captured by a Kinect sensor and segmented according to the distance to the robot. After the segmentation, the input point cloud data are processed by the Approximate Voxel Grid Filter algorithm in different sized voxel grids. Second, the initial registration and precise registration are performed respectively according to the distance to the sensor. The most distant point cloud data use the 3D-Normal Distributions Transform algorithm (3D-NDT with large-sized voxel grids for initial registration, based on the transformation matrix from the odometry method. The closest point cloud data use the 3D-NDT algorithm with small-sized voxel grids for precise registration. After the registrations above, a final transformation matrix is obtained and coordinated. Based on this transformation matrix, the pose estimation problem of the indoor mobile robot is solved. Test results show that this method can obtain accurate robot pose estimation and has better robustness.

  12. Radiation protection and safety guide no. GRPB-G-2: notification and authorization by registration or licensing, exemption and exclusion

    International Nuclear Information System (INIS)

    Schandorf, C.; Darko, O.; Yeboah, J.; Osei, E.K.; Asiamah, S.D.

    1995-01-01

    The obligatory requirement for the notification of the Radiation Protection Board and application for authorization by registration or licensing are important elements of the national system for controlling radiation sources and practices which may be potentially harmful to people. The present document provides guidance for Notification and Authorization by Registration or Licensing. In pursuance of the provision of the Radiation Protection Instrument, 1993, L I 1559, Part II C ontrol and Use of Radiation Sources , the present Guide specifies the Radiation Protection Board (RPB) scheme of notification and authorization by registration of licensing. Criteria for exempting and excluding sources and practices from regulatory control are highlighted

  13. Surface-to-surface registration using level sets

    DEFF Research Database (Denmark)

    Hansen, Mads Fogtmann; Erbou, Søren G.; Vester-Christensen, Martin

    2007-01-01

    This paper presents a general approach for surface-to-surface registration (S2SR) with the Euclidean metric using signed distance maps. In addition, the method is symmetric such that the registration of a shape A to a shape B is identical to the registration of the shape B to the shape A. The S2SR...... problem can be approximated by the image registration (IR) problem of the signed distance maps (SDMs) of the surfaces confined to some narrow band. By shrinking the narrow bands around the zero level sets the solution to the IR problem converges towards the S2SR problem. It is our hypothesis...... that this approach is more robust and less prone to fall into local minima than ordinary surface-to-surface registration. The IR problem is solved using the inverse compositional algorithm. In this paper, a set of 40 pelvic bones of Duroc pigs are registered to each other w.r.t. the Euclidean transformation...

  14. Mammogram CAD, hybrid registration and iconic analysis

    Science.gov (United States)

    Boucher, A.; Cloppet, F.; Vincent, N.

    2013-03-01

    This paper aims to develop a computer aided diagnosis (CAD) based on a two-step methodology to register and analyze pairs of temporal mammograms. The concept of "medical file", including all the previous medical information on a patient, enables joint analysis of different acquisitions taken at different times, and the detection of significant modifications. The developed registration method aims to superimpose at best the different anatomical structures of the breast. The registration is designed in order to get rid of deformation undergone by the acquisition process while preserving those due to breast changes indicative of malignancy. In order to reach this goal, a referent image is computed from control points based on anatomical features that are extracted automatically. Then the second image of the couple is realigned on the referent image, using a coarse-to-fine approach according to expert knowledge that allows both rigid and non-rigid transforms. The joint analysis detects the evolution between two images representing the same scene. In order to achieve this, it is important to know the registration error limits in order to adapt the observation scale. The approach used in this paper is based on an image sparse representation. Decomposed in regular patterns, the images are analyzed under a new angle. The evolution detection problem has many practical applications, especially in medical images. The CAD is evaluated using recall and precision of differences in mammograms.

  15. Family Registration Card as electronic medical carrier in Bosnia and Herzegovina.

    Science.gov (United States)

    Novo, Ahmed; Masic, Izet; Toromanovic, Selim; Loncarevic, Nedim; Junuzovic, Dzelaludin; Dizdarevic, Jadranka

    2004-01-01

    Medical documentation is a very important part of the medical documentalistics and is occupies a large part of daily work of medical staff working in Primary Health Care. Paper documentation is going to be replaced by electronic cards in Bosnia and Herzegovina and a new Health Care System is under development, based on an Electronic Family Registration Card. Developed countries proceeded from the manual and semiautomatic method of medical data processing to the new method of entering, storage, transferring, searching and protecting data, using electronic equipment. Currently, many European countries have developed a Medical Card Based Electronic Information System. Three types of electronic card are currently in use: a Hybrid Card, a Smart Card and a Laser Card. The dilemma is which card should be used as a data carrier. The Electronic Family Registration Cared is a question of strategic interest for B&H, but also a great investment. We should avoid the errors of other countries that have been developing card-based system. In this article we present all mentioned cards and compare advantages and disadvantages of different technologies.

  16. Contacts in the Office of Pesticide Programs, Registration Division

    Science.gov (United States)

    The Registration Division (RD) is responsible product registrations, amendments, registrations, tolerances, experimental use permits, and emergency exemptions for conventional chemical pesticides. Find contacts in this division.

  17. Automatic intra-modality brain image registration method

    International Nuclear Information System (INIS)

    Whitaker, J.M.; Ardekani, B.A.; Braun, M.

    1996-01-01

    Full text: Registration of 3D images of brain of the same or different subjects has potential importance in clinical diagnosis, treatment planning and neurological research. The broad aim of our work is to produce an automatic and robust intra-modality, brain image registration algorithm for intra-subject and inter-subject studies. Our algorithm is composed of two stages. Initial alignment is achieved by finding the values of nine transformation parameters (representing translation, rotation and scale) that minimise the nonoverlapping regions of the head. This is achieved by minimisation of the sum of the exclusive OR of two binary head images, produced using the head extraction procedure described by Ardekani et al. (J Comput Assist Tomogr, 19:613-623, 1995). The initial alignment successfully determines the scale parameters and gross translation and rotation parameters. Fine alignment uses an objective function described for inter-modality registration in Ardekani et al. (ibid.). The algorithm segments one of the images to be aligned into a set of connected components using K-means clustering. Registration is achieved by minimising the K-means variance of the segmentation induced in the other image. Similarity of images of the same modality makes the method attractive for intra-modality registration. A 3D MR image, with voxel dimensions, 2x2x6 mm, was misaligned. The registered image shows visually accurate registration. The average displacement of a pixel from its correct location was measured to be 3.3 mm. The algorithm was tested on intra-subject MR images and was found to produce good qualitative results. Using the data available, the algorithm produced promising qualitative results in intra-subject registration. Further work is necessary in its application to intersubject registration, due to large variability in brain structure between subjects. Clinical evaluation of the algorithm for selected applications is required

  18. A prospective comparison between auto-registration and manual registration of real-time ultrasound with MR images for percutaneous ablation or biopsy of hepatic lesions.

    Science.gov (United States)

    Cha, Dong Ik; Lee, Min Woo; Song, Kyoung Doo; Oh, Young-Taek; Jeong, Ja-Yeon; Chang, Jung-Woo; Ryu, Jiwon; Lee, Kyong Joon; Kim, Jaeil; Bang, Won-Chul; Shin, Dong Kuk; Choi, Sung Jin; Koh, Dalkwon; Seo, Bong Koo; Kim, Kyunga

    2017-06-01

    To compare the accuracy and required time for image fusion of real-time ultrasound (US) with pre-procedural magnetic resonance (MR) images between positioning auto-registration and manual registration for percutaneous radiofrequency ablation or biopsy of hepatic lesions. This prospective study was approved by the institutional review board, and all patients gave written informed consent. Twenty-two patients (male/female, n = 18/n = 4; age, 61.0 ± 7.7 years) who were referred for planning US to assess the feasibility of radiofrequency ablation (n = 21) or biopsy (n = 1) for focal hepatic lesions were included. One experienced radiologist performed the two types of image fusion methods in each patient. The performance of auto-registration and manual registration was evaluated. The accuracy of the two methods, based on measuring registration error, and the time required for image fusion for both methods were recorded using in-house software and respectively compared using the Wilcoxon signed rank test. Image fusion was successful in all patients. The registration error was not significantly different between the two methods (auto-registration: median, 3.75 mm; range, 1.0-15.8 mm vs. manual registration: median, 2.95 mm; range, 1.2-12.5 mm, p = 0.242). The time required for image fusion was significantly shorter with auto-registration than with manual registration (median, 28.5 s; range, 18-47 s, vs. median, 36.5 s; range, 14-105 s, p = 0.026). Positioning auto-registration showed promising results compared with manual registration, with similar accuracy and even shorter registration time.

  19. High performance deformable image registration algorithms for manycore processors

    CERN Document Server

    Shackleford, James; Sharp, Gregory

    2013-01-01

    High Performance Deformable Image Registration Algorithms for Manycore Processors develops highly data-parallel image registration algorithms suitable for use on modern multi-core architectures, including graphics processing units (GPUs). Focusing on deformable registration, we show how to develop data-parallel versions of the registration algorithm suitable for execution on the GPU. Image registration is the process of aligning two or more images into a common coordinate frame and is a fundamental step to be able to compare or fuse data obtained from different sensor measurements. E

  20. REGISTRATION OF OVERLAPPING 3D POINT CLO UDS USING EXTRACTED LINE SEGMENTS

    Directory of Open Access Journals (Sweden)

    Poręba Martyna

    2014-12-01

    Full Text Available The registration of 3D point clouds collected from different scanner positions is necessary in order to avoid occlusions, ensure a full coverage of areas, and collect useful data for analyzing an d documenting the surrounding environment. This procedure involves three main stages: 1 choosing appropriate features, which can be reliably extracted; 2 matching conjugate primitives; 3 estimating the transformation parameters. Currently, points and spheres are most frequently chosen as the registration features. However, due to limited point cloud resolution, proper identification and precise measurement of a common point within the overlapping laser data is almost impossible. One possible solution to this problem may be a registration process based on the Iterative Closest Point (ICP algorithm or its variation. Alternatively, planar and linear feature - based registration techniques can also be applied. In this paper, we propose the use of line segments obtained from intersecting planes modelled within individual scans. Such primitives can be easily extracted even from low - density point clouds. Working with synthetic data, several existing line - based registration methods are evaluated according to their robustness to noise and the precision of the estimated transformation parameters. For the purpose of quantitative assessment, an accuracy criterion based on a modified Hausdorff distance is defined. Since a n automated matching of segments is a challenging task that influences the correctness of the transformation parameters, a correspondence - finding algorithm is developed. The tests show that our matching algorithm provides a correct pairing with an accuracy of 99 % at least, and about 8% of omitted line pairs.

  1. Inverse consistent non-rigid image registration based on robust point set matching

    Science.gov (United States)

    2014-01-01

    Background Robust point matching (RPM) has been extensively used in non-rigid registration of images to robustly register two sets of image points. However, except for the location at control points, RPM cannot estimate the consistent correspondence between two images because RPM is a unidirectional image matching approach. Therefore, it is an important issue to make an improvement in image registration based on RPM. Methods In our work, a consistent image registration approach based on the point sets matching is proposed to incorporate the property of inverse consistency and improve registration accuracy. Instead of only estimating the forward transformation between the source point sets and the target point sets in state-of-the-art RPM algorithms, the forward and backward transformations between two point sets are estimated concurrently in our algorithm. The inverse consistency constraints are introduced to the cost function of RPM and the fuzzy correspondences between two point sets are estimated based on both the forward and backward transformations simultaneously. A modified consistent landmark thin-plate spline registration is discussed in detail to find the forward and backward transformations during the optimization of RPM. The similarity of image content is also incorporated into point matching in order to improve image matching. Results Synthetic data sets, medical images are employed to demonstrate and validate the performance of our approach. The inverse consistent errors of our algorithm are smaller than RPM. Especially, the topology of transformations is preserved well for our algorithm for the large deformation between point sets. Moreover, the distance errors of our algorithm are similar to that of RPM, and they maintain a downward trend as whole, which demonstrates the convergence of our algorithm. The registration errors for image registrations are evaluated also. Again, our algorithm achieves the lower registration errors in same iteration number

  2. Visitor Registration System

    Data.gov (United States)

    US Agency for International Development — Visitor Registration System (VRS) streamlines visitor check-in and check-out process for expediting visitors into USAID. The system captures visitor information...

  3. Study of three-dimensional PET and MR image registration based on higher-order mutual information

    International Nuclear Information System (INIS)

    Ren Haiping; Chen Shengzu; Wu Wenkai; Yang Hu

    2002-01-01

    Mutual information has currently been one of the most intensively researched measures. It has been proven to be accurate and effective registration measure. Despite the general promising results, mutual information sometimes might lead to misregistration because of neglecting spatial information and treating intensity variations with undue sensitivity. An extension of mutual information framework was proposed in which higher-order spatial information regarding image structures was incorporated into the registration processing of PET and MR. The second-order estimate of mutual information algorithm was applied to the registration of seven patients. Evaluation from Vanderbilt University and authors' visual inspection showed that sub-voxel accuracy and robust results were achieved in all cases with second-order mutual information as the similarity measure and with Powell's multidimensional direction set method as optimization strategy

  4. 12 CFR 998.2 - Registration and periodic disclosures.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Registration and periodic disclosures. 998.2 Section 998.2 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOME LOAN BANK DISCLOSURES REGISTRATION OF FEDERAL HOME LOAN BANK EQUITY SECURITIES § 998.2 Registration and periodic disclosures. (a...

  5. 17 CFR 31.6 - Registration of leverage commodities.

    Science.gov (United States)

    2010-04-01

    ... taking delivery to buy or sell the leverage commodity; (2) Explain the effect of such changes upon the... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Registration of leverage... LEVERAGE TRANSACTIONS § 31.6 Registration of leverage commodities. (a) Registration of leverage commodities...

  6. Iaverage current mode (ACM) control for switching power converters

    OpenAIRE

    2014-01-01

    Providing a fast current sensor direct feedback path to a modulator for controlling switching of a switched power converter in addition to an integrating feedback path which monitors average current for control of a modulator provides fast dynamic response consistent with system stability and average current mode control. Feedback of output voltage for voltage regulation can be combined with current information in the integrating feedback path to limit bandwidth of the voltage feedback signal.

  7. 40 CFR 152.99 - Petitions to cancel registration.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Petitions to cancel registration. 152... Submitters' Rights § 152.99 Petitions to cancel registration. An original data submitter may petition the Agency to deny or cancel the registration of a product in accordance with this section if he has...

  8. 49 CFR 107.503 - Registration statement.

    Science.gov (United States)

    2010-10-01

    ... tank motor vehicles which the registrant intends to manufacture, assemble, repair, inspect, test or... this section, each person who repairs a cargo tank or cargo tank motor vehicle must submit a copy of... PROGRAM PROCEDURES Registration of Cargo Tank and Cargo Tank Motor Vehicle Manufacturers, Assemblers...

  9. 3D/2D model-to-image registration by imitation learning for cardiac procedures.

    Science.gov (United States)

    Toth, Daniel; Miao, Shun; Kurzendorfer, Tanja; Rinaldi, Christopher A; Liao, Rui; Mansi, Tommaso; Rhode, Kawal; Mountney, Peter

    2018-05-12

    In cardiac interventions, such as cardiac resynchronization therapy (CRT), image guidance can be enhanced by involving preoperative models. Multimodality 3D/2D registration for image guidance, however, remains a significant research challenge for fundamentally different image data, i.e., MR to X-ray. Registration methods must account for differences in intensity, contrast levels, resolution, dimensionality, field of view. Furthermore, same anatomical structures may not be visible in both modalities. Current approaches have focused on developing modality-specific solutions for individual clinical use cases, by introducing constraints, or identifying cross-modality information manually. Machine learning approaches have the potential to create more general registration platforms. However, training image to image methods would require large multimodal datasets and ground truth for each target application. This paper proposes a model-to-image registration approach instead, because it is common in image-guided interventions to create anatomical models for diagnosis, planning or guidance prior to procedures. An imitation learning-based method, trained on 702 datasets, is used to register preoperative models to intraoperative X-ray images. Accuracy is demonstrated on cardiac models and artificial X-rays generated from CTs. The registration error was [Formula: see text] on 1000 test cases, superior to that of manual ([Formula: see text]) and gradient-based ([Formula: see text]) registration. High robustness is shown in 19 clinical CRT cases. Besides the proposed methods feasibility in a clinical environment, evaluation has shown good accuracy and high robustness indicating that it could be applied in image-guided interventions.

  10. Transparency of outcome reporting and trial registration of randomized controlled trials in top psychosomatic and behavioral health journals: A systematic review.

    Science.gov (United States)

    Milette, Katherine; Roseman, Michelle; Thombs, Brett D

    2011-03-01

    The most reliable evidence for evaluating healthcare interventions comes from well-designed and conducted randomized controlled trials (RCTs). The extent to which published RCTs reflect the efficacy of interventions, however, depends on the completeness and accuracy of published results. The Consolidated Standards of Reporting Trials statement, initially developed in 1996, provides guidelines intended to improve the transparency of published RCT reports. A policy of the International Committee of Medical Journal Editors, initiated in 2005, requires clinical trials published in member journals to be registered in publicly accessible registries prior to patient enrollment. The objective of this study was to assess the clarity of outcome reporting, proportion of registered trials, and adequacy of outcome registration in RCTs published in top behavioral health journals. Eligible studies were primary or secondary reports of RCTs published in Annals of Behavioral Medicine, Health Psychology, Journal of Psychosomatic Research, and Psychosomatic Medicine from January 2008 to September 2009. Data were extracted for each study on adequacy of outcome reporting and registration. Of 63 articles reviewed, only 25 (39.7%) had adequately declared primary or secondary outcomes, whereas 38 (60.3%) had multiple primary outcomes or did not define outcomes. Only 13 studies (20.6%) were registered. Only 1 study registered sufficiently precise outcome information to compare with published outcomes, and registered and published outcomes were discrepant in that study. Greater attention to outcome reporting and trial registration by researchers, peer reviewers, and journal editors will increase the likelihood that effective behavioral health interventions are readily identified and made available to patients. Copyright © 2011 Elsevier Inc. All rights reserved.

  11. Results of a voter registration project at 2 family medicine residency clinics in the Bronx, New York.

    Science.gov (United States)

    Liggett, Alisha; Sharma, Manisha; Nakamura, Yumiko; Villar, Ryna; Selwyn, Peter

    2014-01-01

    Federally qualified health centers provide care to medically underserved populations, the same individuals often underrepresented in the electoral process. These centers are unique venues to access patients for voter registration services. We undertook a clinician-led, nonpartisan voter registration drive within 2 university-affiliated federally qualified health centers in the Bronx, New York. Patients were approached by voter registration volunteers in clinic waiting areas during a 12-week period. Volunteers directly engaged with 304 patients. Of the 128 patients who were eligible and not currently registered, 114 (89%) registered to vote through this project. This number corresponded to 38% of all patients engaged. Sixty-five percent of new registrants were aged younger than 40 years. This project was successful in registering clinic patients to vote. Clinics are not only health centers, but also powerful vehicles for bringing a voice to civically disenfranchised communities. © 2014 Annals of Family Medicine, Inc.

  12. Use of volume-rendered images in registration of nuclear medicine studies

    International Nuclear Information System (INIS)

    Wallis, J.W.; Miller, T.R.; Hsu, S.S.

    1995-01-01

    A simple operator-guided alignment technique based on volume-rendered images was developed to register tomographic nuclear medicine studies. For each of 2 three-dimensional data sets to be registered, volume-rendered images were generated in 3 orthogonal projections (x,y,z) using the method of maximum-activity projection. Registration was achieved as follows: (a) One of the rendering orientations (e.g. x) was chosen for manipulation; (b) The two dimensional rendering was translated and rotated under operator control to achieve the best alignment as determined by visual assessment; (c) This rotation and translation was then applied to the underlying three-dimensional data set, with updating of the rendered images in each of the orthogonal projections; (d) Another orientation was chosen, and the process repeated. Since manipulation was performed on the small two-dimensional rendered image, feedback was instantaneous. To aid in the visual alignment, difference images and flicker images (toggling between the two data sets) were displayed. Accuracy was assessed by analysis of separate clinical data sets acquired without patient movement. After arbitrary rotation and translation of one of the two data sets, the 2 data sets were registered. Mean registration error was 0.36 pixels, corresponding to a 2.44 mm registration error. Thus, accurate registration can be achieved in under 10 minutes using this simple technique. The accuracy of registration was assessed with use of duplicate SPECT studies originating from separate reconstructions of the data from each of the detectors of a triple-head gamma camera

  13. 32 CFR 636.9 - Registration requirement.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Registration requirement. 636.9 Section 636.9 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION (SPECIFIC INSTALLATIONS) Fort Stewart, Georgia § 636.9 Registration requirement. In...

  14. Fast fluid registration of medical images

    DEFF Research Database (Denmark)

    Bro-Nielsen, Morten; Gramkow, Claus

    1996-01-01

    This paper offers a new fast algorithm for non-rigid viscous fluid registration of medical images that is at least an order of magnitude faster than the previous method by (Christensen et al., 1994). The core algorithm in the fluid registration method is based on a linear elastic deformation...

  15. A first step toward uncovering the truth about weight tuning in deformable image registration

    NARCIS (Netherlands)

    K. Pirpinia (Kleopatra); P.A.N. Bosman (Peter); J.-J. Sonke (Jan-Jakob); M. van Herk (Marcel); T. Alderliesten (Tanja)

    2016-01-01

    textabstractDeformable image registration is currently predominantly solved by optimizing a weighted linear combination of objectives. Successfully tuning the weights associated with these objectives is not trivial, leading to trial-and-error approaches. Such an approach assumes an intuitive

  16. 7 CFR 331.7 - Registration and related security risk assessments.

    Science.gov (United States)

    2010-01-01

    ... own or control the entity if the individual is in a managerial or executive capacity with regard to... stock; or (B) Is in a managerial or executive capacity with regard to the entity's select agents or... certificate of registration may be contingent upon inspection or submission of additional information, such as...

  17. Geometric registration of remotely sensed data with SAMIR

    Science.gov (United States)

    Gianinetto, Marco; Barazzetti, Luigi; Dini, Luigi; Fusiello, Andrea; Toldo, Roberto

    2015-06-01

    The commercial market offers several software packages for the registration of remotely sensed data through standard one-to-one image matching. Although very rapid and simple, this strategy does not take into consideration all the interconnections among the images of a multi-temporal data set. This paper presents a new scientific software, called Satellite Automatic Multi-Image Registration (SAMIR), able to extend the traditional registration approach towards multi-image global processing. Tests carried out with high-resolution optical (IKONOS) and high-resolution radar (COSMO-SkyMed) data showed that SAMIR can improve the registration phase with a more rigorous and robust workflow without initial approximations, user's interaction or limitation in spatial/spectral data size. The validation highlighted a sub-pixel accuracy in image co-registration for the considered imaging technologies, including optical and radar imagery.

  18. Current control loop of 3-phase grid-connected inverter

    International Nuclear Information System (INIS)

    Jabbar, A F; Mansor, M

    2013-01-01

    This paper presents a comparative study of current control loop in 3-phase inverter which is used to control the active and reactive output power. Generally, current control loop, power control loop and phase lock-loop are the conventional parameters that can be found in an inverter system controlled by the conventional linear control type, for instance proportional (P), integral (I) and derivative (D). If the grid remains stable throughout the day, PID control can be use. However variation of magnitude, frequency, voltage dips, transient, and other related power quality issues occur in a 3-phase grid often affects the control loop. This paper aims to provide an overall review on the available current control techniques used in grid connected system.

  19. Registration in the Danish Regional Nonmelanoma Skin Cancer Dermatology Database: completeness of registration and accuracy of key variables

    Directory of Open Access Journals (Sweden)

    Anna L Lamberg

    2010-05-01

    Full Text Available Anna L Lamberg1, Deirdre Cronin-Fenton2, Anne B Olesen11Department of Dermatology, 2Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, C, DenmarkObjective: To validate a clinical database for nonmelanoma skin cancer (NMSC with the aim of monitoring and predicting the prognosis of NMSC treated by dermatologists in clinics in the central and north Denmark regions.Methods: We assessed the completeness of registration of patients and follow-up visits, and positive predictive value (PPV, negative predictive value (NPV, sensitivity, and specificity of registrations in the database. We used the Danish Pathology Registry (DPR (n = 288 and a review of randomly selected medical records (n = 67 from two clinics as gold standards.Results: The completeness of registration of patients was 62% and 76% with DPR and medical record review as gold standards, respectively. The completeness of registration of 1st and 2nd follow up visits was 85% and 69%, respectively. The PPV and NPV ranged from 85% to 99%, and the sensitivity and specificity from 67% to 100%.Conclusion: Overall, the accuracy of variables registered in the NMSC database was satisfactory but completeness of patient registration and follow-up visits were modest. The NMSC database is a potentially valuable tool for monitoring and facilitating improvement of NMSC treatment in dermatology clinics. However, there is still room for improvement of registration of both patients and their follow-up visits.Keywords: nonmelanoma skin cancer, validation, database, positive predictive value, completeness

  20. Eddy current quality control of soldered current-carrying busbar splices of superconducting magnets

    CERN Document Server

    Kogan, L; Savary, F; Principe, R; Datskov, V; Rozenfel'd, E; Khudjakov, B

    2015-01-01

    The eddy current technique associated with a U-shaped transducer is studied for the quality control of soldered joints between superconducting busbars ('splices'). Two other quality control techniques, based on X-rays and direct measurement of the electrical resistance, are also studied for comparison. A comparative analysis of the advantages and disadvantages of these three methods in relation to the quality control of soldered superconducting busbar cables enclosed in copper shells is used for benchmarking. The results of inspections with the U-shaped eddy current transducer carried out on several sample joints presenting different types of soldering defects show the potential of this type of nondestructive (ND) quality control technique.

  1. 27 CFR 25.112 - Dealer registration.

    Science.gov (United States)

    2010-04-01

    .... Every brewer who sells, or offers for sale, any alcohol product (distilled spirits, wines, or beer) fit... registration. Registration covers all sales from the same location, including sales of wine, spirits, or other... for making sales of wine or beer at the customer's place of business. Otherwise, a brewer who conducts...

  2. Tenure Security Reformand Electronic Registration: Exploring ...

    African Journals Online (AJOL)

    This paper examines the potential significance of updating registration practices in resolving some of the issues about tenure security in a transformative context. It deals with the importance of good governance in the context of land administration and considers its impact on intended reforms. Land registration practice as an ...

  3. 19 CFR 360.102 - Online registration.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Online registration. 360.102 Section 360.102... ANALYSIS SYSTEM § 360.102 Online registration. (a) In general. (1) Any importer, importing company, customs.... boxes will not be accepted. A user identification number will be issued within two business days...

  4. Zener diode controls switching of large direct currents

    Science.gov (United States)

    1965-01-01

    High-current zener diode is connected in series with the positive input terminal of a dc supply to block the flow of direct current until a high-frequency control signal is applied across the zener diode. This circuit controls the switching of large dc signals.

  5. Survey of Non-Rigid Registration Tools in Medicine.

    Science.gov (United States)

    Keszei, András P; Berkels, Benjamin; Deserno, Thomas M

    2017-02-01

    We catalogue available software solutions for non-rigid image registration to support scientists in selecting suitable tools for specific medical registration purposes. Registration tools were identified using non-systematic search in Pubmed, Web of Science, IEEE Xplore® Digital Library, Google Scholar, and through references in identified sources (n = 22). Exclusions are due to unavailability or inappropriateness. The remaining (n = 18) tools were classified by (i) access and technology, (ii) interfaces and application, (iii) living community, (iv) supported file formats, and (v) types of registration methodologies emphasizing the similarity measures implemented. Out of the 18 tools, (i) 12 are open source, 8 are released under a permissive free license, which imposes the least restrictions on the use and further development of the tool, 8 provide graphical processing unit (GPU) support; (ii) 7 are built on software platforms, 5 were developed for brain image registration; (iii) 6 are under active development but only 3 have had their last update in 2015 or 2016; (iv) 16 support the Analyze format, while 7 file formats can be read with only one of the tools; and (v) 6 provide multiple registration methods and 6 provide landmark-based registration methods. Based on open source, licensing, GPU support, active community, several file formats, algorithms, and similarity measures, the tools Elastics and Plastimatch are chosen for the platform ITK and without platform requirements, respectively. Researchers in medical image analysis already have a large choice of registration tools freely available. However, the most recently published algorithms may not be included in the tools, yet.

  6. Wavelet based free-form deformations for nonrigid registration

    Science.gov (United States)

    Sun, Wei; Niessen, Wiro J.; Klein, Stefan

    2014-03-01

    In nonrigid registration, deformations may take place on the coarse and fine scales. For the conventional B-splines based free-form deformation (FFD) registration, these coarse- and fine-scale deformations are all represented by basis functions of a single scale. Meanwhile, wavelets have been proposed as a signal representation suitable for multi-scale problems. Wavelet analysis leads to a unique decomposition of a signal into its coarse- and fine-scale components. Potentially, this could therefore be useful for image registration. In this work, we investigate whether a wavelet-based FFD model has advantages for nonrigid image registration. We use a B-splines based wavelet, as defined by Cai and Wang.1 This wavelet is expressed as a linear combination of B-spline basis functions. Derived from the original B-spline function, this wavelet is smooth, differentiable, and compactly supported. The basis functions of this wavelet are orthogonal across scales in Sobolev space. This wavelet was previously used for registration in computer vision, in 2D optical flow problems,2 but it was not compared with the conventional B-spline FFD in medical image registration problems. An advantage of choosing this B-splines based wavelet model is that the space of allowable deformation is exactly equivalent to that of the traditional B-spline. The wavelet transformation is essentially a (linear) reparameterization of the B-spline transformation model. Experiments on 10 CT lung and 18 T1-weighted MRI brain datasets show that wavelet based registration leads to smoother deformation fields than traditional B-splines based registration, while achieving better accuracy.

  7. 37 CFR 202.20 - Deposit of copies and phonorecords for copyright registration.

    Science.gov (United States)

    2010-07-01

    ... published in both hard copy, i.e., in a physically tangible format, and also in an electronic format, the current Library of Congress Best Edition Statement requirements pertaining to the hard copy format apply... registration in digital formats. A ‘complete’ electronically filed work is one which is embodied in a digital...

  8. Fast parallel image registration on CPU and GPU for diagnostic classification of Alzheimer's disease.

    Science.gov (United States)

    Shamonin, Denis P; Bron, Esther E; Lelieveldt, Boudewijn P F; Smits, Marion; Klein, Stefan; Staring, Marius

    2013-01-01

    Nonrigid image registration is an important, but time-consuming task in medical image analysis. In typical neuroimaging studies, multiple image registrations are performed, i.e., for atlas-based segmentation or template construction. Faster image registration routines would therefore be beneficial. In this paper we explore acceleration of the image registration package elastix by a combination of several techniques: (i) parallelization on the CPU, to speed up the cost function derivative calculation; (ii) parallelization on the GPU building on and extending the OpenCL framework from ITKv4, to speed up the Gaussian pyramid computation and the image resampling step; (iii) exploitation of certain properties of the B-spline transformation model; (iv) further software optimizations. The accelerated registration tool is employed in a study on diagnostic classification of Alzheimer's disease and cognitively normal controls based on T1-weighted MRI. We selected 299 participants from the publicly available Alzheimer's Disease Neuroimaging Initiative database. Classification is performed with a support vector machine based on gray matter volumes as a marker for atrophy. We evaluated two types of strategies (voxel-wise and region-wise) that heavily rely on nonrigid image registration. Parallelization and optimization resulted in an acceleration factor of 4-5x on an 8-core machine. Using OpenCL a speedup factor of 2 was realized for computation of the Gaussian pyramids, and 15-60 for the resampling step, for larger images. The voxel-wise and the region-wise classification methods had an area under the receiver operator characteristic curve of 88 and 90%, respectively, both for standard and accelerated registration. We conclude that the image registration package elastix was substantially accelerated, with nearly identical results to the non-optimized version. The new functionality will become available in the next release of elastix as open source under the BSD license.

  9. Operation of the radiation dose registration system for decontamination and related works

    International Nuclear Information System (INIS)

    Ogawa, Tsubasa; Yasutake, Tsuneo; Itoh, Atsuo; Miyabe, Kenjiro

    2017-01-01

    The radiation dose registration system for decontamination and related works was established on 15 November 2013. Radiation dose registration center and primary contractors of decontamination and related works manage decontamination registration and management system. As of 31 March 2017, 384 primary contractors joined in the radiation dose registration system for decontamination and related works. 383,087 quarterly exposure dose records for decontamination and related works were registered. Based on the registered data provided by the primary contractors, radiation dose registration center has released the statistical data that represent the radiation control status for workers engaged in radiation work at the work areas of decontamination and related works, etc. The statistical data shows that there were 40,377 workers engaged in decontamination and related works in 2015. The average exposure dose for workers was 0.6 mSv in 2015. The maximum exposure dose for workers was 7.8 mSv in 2015. Dose distribution by age of workers shows the range of 60 to 64 years old were most engaged in decontamination and related works in 2015. Dose distribution by gender of workers shows 97% of workers were male in 2015. From 2012 to 2015, about 95% of workers were exposed to radiation less than 3 mSv. And about 80% of workers were exposed to radiation less than 1 mSv. The average exposure dose per year was ranged from 0.5 to 0.7 mSv. (author)

  10. Efficient Variational Approaches for Deformable Registration of Images

    Directory of Open Access Journals (Sweden)

    Mehmet Ali Akinlar

    2012-01-01

    Full Text Available Dirichlet, anisotropic, and Huber regularization terms are presented for efficient registration of deformable images. Image registration, an ill-posed optimization problem, is solved using a gradient-descent-based method and some fundamental theorems in calculus of variations. Euler-Lagrange equations with homogeneous Neumann boundary conditions are obtained. These equations are discretized by multigrid and finite difference numerical techniques. The method is applied to the registration of brain MR images of size 65×65. Computational results indicate that the presented method is quite fast and efficient in the registration of deformable medical images.

  11. Current control for magnetized plasma in direct-current plasma-immersion ion implantation

    International Nuclear Information System (INIS)

    Tang Deli; Chu, Paul K.

    2003-01-01

    A method to control the ion current in direct-current plasma-immersion ion implantation (PIII) is reported for low-pressure magnetized inductively coupled plasma. The ion current can be conveniently adjusted by applying bias voltage to the conducting grid that separates plasma formation and implantation (ion acceleration) zones without the need to alter the rf input power, gas flux, or other operating conditions. The ion current that diminishes with an increase in grid bias in magnetized plasmas can be varied from 48 to 1 mA by increasing the grid voltage from 0 to 70 V at -50 kV sample bias and 0.5 mTorr hydrogen pressure. High implantation voltage and monoenergetic immersion implantation can now be achieved by controlling the ion current without varying the macroscopic plasma parameters. The experimental results and interpretation of the effects are presented in this letter. This technique is very attractive for PIII of planar samples that require on-the-fly adjustment of the implantation current at high implantation voltage but low substrate temperature. In some applications such as hydrogen PIII-ion cut, it may obviate the need for complicated sample cooling devices that must work at high voltage

  12. Simultaneous 3D–2D image registration and C-arm calibration: Application to endovascular image-guided interventions

    Energy Technology Data Exchange (ETDEWEB)

    Mitrović, Uroš [Faculty of Electrical Engineering, University of Ljubljana, Tržaška 25, Ljubljana 1000, Slovenia and Cosylab, Control System Laboratory, Teslova ulica 30, Ljubljana 1000 (Slovenia); Pernuš, Franjo [Faculty of Electrical Engineering, University of Ljubljana, Tržaška 25, Ljubljana 1000 (Slovenia); Likar, Boštjan; Špiclin, Žiga, E-mail: ziga.spiclin@fe.uni-lj.si [Faculty of Electrical Engineering, University of Ljubljana, Tržaška 25, Ljubljana 1000, Slovenia and Sensum, Computer Vision Systems, Tehnološki Park 21, Ljubljana 1000 (Slovenia)

    2015-11-15

    template matching and final registration involving C-arm calibration were 36%, 73%, and 93%, respectively, while registration accuracy of 0.59 mm was the best after final registration. By compensating in-plane translation errors by initial template matching, the success rates achieved after the final stage improved consistently for all methods, especially if C-arm calibration was performed simultaneously with the 3D–2D image registration. Conclusions: Because the tested methods perform simultaneous C-arm calibration and 3D–2D registration based solely on anatomical information, they have a high potential for automation and thus for an immediate integration into current interventional workflow. One of the authors’ main contributions is also comprehensive and representative validation performed under realistic conditions as encountered during cerebral EIGI.

  13. Current control by ECCD for W7-X

    International Nuclear Information System (INIS)

    Turkin, Yu.; Maassberg, H.; Beidler, C.D.; Geiger, J.; Marushchenko, N.B.

    2005-01-01

    One of the optimization criteria for the stellarator W7-X is the minimization of the bootstrap current. The plasma current changes the magnetic configuration, especially near the plasma edge, where X-points and islands are located. It was shown that the plasma parameter distributions in the divertor region and the particle and energy depositions on the divertor plates depend strongly on the island geometry. An estimation of the tolerable plasma current obtained from the shift of the island structure close to the target plates shows that the plasma current should be controlled within a range of about 10 kA. The bootstrap current even for the standard configuration can easily exceed this value. The W7-X is not equipped with an Ohmic transformer, so the only means for compensating this current is electron cyclotron current drive (ECCD) and/or neutral beam current drive (NBCD). In this report we study the compensation of residual bootstrap current by using ECCD. To model the control of the toroidal current we use a predictive 1D transport code, which is under development. For evaluation of the bootstrap current and neoclassical transport coefficients we use results from an international collaboration on neoclassical transport in stellarators. Power deposition and current drive profiles due to electron cyclotron resonance heating are calculated by a new ray tracing code. The modeling showed that the loop voltage induced by ECCD leads to a redistribution of the current density with the diffusion time of about two seconds. The relaxation time of the total current is much longer than this time - for a typical ECRH-plasma the total toroidal current reaches steady state after several L/R-time that is about hundreds of seconds. In order to keep current in an acceptable range and to avoid long relaxation times we propose Feed-forward or Predictive control using ECCD as actuator, the steps are as follows: - calculate the bootstrap current distribution using measured plasma

  14. 21 CFR 1309.45 - Extension of registration pending final order.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Extension of registration pending final order. 1309.45 Section 1309.45 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE... for Registration: Revocation Or Suspension of Registration § 1309.45 Extension of registration pending...

  15. 32 CFR 636.8 - Registration policy.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Registration policy. 636.8 Section 636.8 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION (SPECIFIC INSTALLATIONS) Fort Stewart, Georgia § 636.8 Registration policy. In addition to th...

  16. Off-axis current drive and real-time control of current profile in JT-60U

    International Nuclear Information System (INIS)

    Suzuki, T.; Ide, S.; Oikawa, T.; Fujita, T.; Ishikawa, M.; Seki, M.; Matsunaga, G.; Hatae, T.; Naito, O.; Hamamatsu, K.; Sueoka, M.; Hosoyama, H.; Nakazato, M.

    2008-01-01

    Aiming at optimization of current profile in high-β plasmas for higher confinement and stability, a real-time control system of the minimum of the safety factor (q min ) using the off-axis current drive has been developed. The off-axis current drive can raise the safety factor in the centre and help to avoid instability that limits the performance of the plasma. The system controls the injection power of lower-hybrid waves, and hence its off-axis driven current in order to control q min . The real-time control of q min is demonstrated in a high-β plasma, where q min follows the temporally changing reference q min,ref from 1.3 to 1.7. Applying the control to another high-β discharge (β N = 1.7, β p = 1.5) with m/n = 2/1 neo-classical tearing mode (NTM), q min was raised above 2 and the NTM was suppressed. The stored energy increased by 16% with the NTM suppressed, since the resonant rational surface was eliminated. For the future use for current profile control, current density profile for off-axis neutral beam current drive (NBCD) is for the first time measured, using the motional Stark effect diagnostic. Spatially localized NBCD profile was clearly observed at the normalized minor radius ρ of about 0.6-0.8. The location was also confirmed by multi-chordal neutron emission profile measurement. The total amount of the measured beam driven current was consistent with the theoretical calculation using the ACCOME code. The CD location in the calculation was inward shifted than the measurement

  17. Prospective registration of clinical trials in India: strategies, achievements & challenges.

    Science.gov (United States)

    Tharyan, Prathap

    2009-02-01

    This paper traces the development of the Clinical Trial Registry-India (CTRI) against the backdrop of the inequities in healthcare and the limitations in the design, conduct, regulation, oversight and reporting of clinical trials in India. It describes the scope and goals of the CTRI, the data elements it seeks and the process of registering clinical trials. It reports progress in trial registration in India and discusses the challenges in ensuring that healthcare decisions are informed by all the evidence. A descriptive survey of developments in clinical trial registration in India from publications in the Indian medical literature supplemented by first hand knowledge of these developments and an evaluation of how well clinical trials registered in the CTRI up to 10 January, 2009 comply with the requirements of the CTRI and the World Health Organization's International Clinical Trial Registry (WHO ICTRP). Considerable inequities exist within the Indian health system. Deficiencies in healthcare provision and uneven regulation of, and access to, affordable healthcare co-exists with a large private health system of uneven quality. India is now a preferred destination for outsourced clinical trials but is plagued by poor ethical oversight of the many trial sites and scant information of their existence. The CTRI's vision of conforming to international requirements for transparency and accountability but also using trial registration as a means of improving trial design, conduct and reporting led to the selection of registry-specific dataset items in addition to those endorsed by the WHO ICTRP. Compliance with these requirements is good for the trials currently registered but these trials represent only a fraction of the trials in progress in India. Prospective trial registration is a reality in India. The challenges facing the CTRI include better engagement with key stakeholders to ensure increased prospective registration of clinical trials and utilization of

  18. elastix: a toolbox for intensity-based medical image registration.

    Science.gov (United States)

    Klein, Stefan; Staring, Marius; Murphy, Keelin; Viergever, Max A; Pluim, Josien P W

    2010-01-01

    Medical image registration is an important task in medical image processing. It refers to the process of aligning data sets, possibly from different modalities (e.g., magnetic resonance and computed tomography), different time points (e.g., follow-up scans), and/or different subjects (in case of population studies). A large number of methods for image registration are described in the literature. Unfortunately, there is not one method that works for all applications. We have therefore developed elastix, a publicly available computer program for intensity-based medical image registration. The software consists of a collection of algorithms that are commonly used to solve medical image registration problems. The modular design of elastix allows the user to quickly configure, test, and compare different registration methods for a specific application. The command-line interface enables automated processing of large numbers of data sets, by means of scripting. The usage of elastix for comparing different registration methods is illustrated with three example experiments, in which individual components of the registration method are varied.

  19. COMPARISON OF VOLUMETRIC REGISTRATION ALGORITHMS FOR TENSOR-BASED MORPHOMETRY.

    Science.gov (United States)

    Villalon, Julio; Joshi, Anand A; Toga, Arthur W; Thompson, Paul M

    2011-01-01

    Nonlinear registration of brain MRI scans is often used to quantify morphological differences associated with disease or genetic factors. Recently, surface-guided fully 3D volumetric registrations have been developed that combine intensity-guided volume registrations with cortical surface constraints. In this paper, we compare one such algorithm to two popular high-dimensional volumetric registration methods: large-deformation viscous fluid registration, formulated in a Riemannian framework, and the diffeomorphic "Demons" algorithm. We performed an objective morphometric comparison, by using a large MRI dataset from 340 young adult twin subjects to examine 3D patterns of correlations in anatomical volumes. Surface-constrained volume registration gave greater effect sizes for detecting morphometric associations near the cortex, while the other two approaches gave greater effects sizes subcortically. These findings suggest novel ways to combine the advantages of multiple methods in the future.

  20. A Modified Droop Control Method for Parallel-Connected Current Source Inverters

    DEFF Research Database (Denmark)

    Wei, Baoze; Guerrero, Josep M.; Quintero, Juan Carlos Vasquez

    2016-01-01

    In this paper, a novel control method was proposed for current source inverters under the grid-connected working mode. The control scheme is based on a modified droop control method, with an additional current reference signal that will be generated instead of the voltage reference. Hence......, there is only a current control loop with droop control in the whole control scheme without voltage control loop. So it is very suitable for grid-connected current source inverter which will simplify the design of the control scheme and combine the advantage of droop control. The parallel configuration...... is widely used to acquire high power demand, but the circulating current problem is a key issue that should be considered. In this paper, a simulation based on parallel current source inverters using the proposed control scheme is provided. Simulation results showed that a good circulating current...

  1. Socioeconomic determinants of accessibility to birth registration in Lao PDR.

    Science.gov (United States)

    Nomura, Marika; Xangsayarath, Phonepadith; Takahashi, Kenzo; Kamiya, Yusuke; Siengsounthone, Latsamy; Ogino, Hina; Kobayashi, Jun

    2018-01-08

    The global coverage rate of birth registration is only around 65% for the population of children under five although birth registration secures protection and access to health services that are fundamental rights for all babies. This study aimed to perform a basic analysis of the accessibility to birth registration to better understand how to improve the birth registration system in the Lao PDR. For the analysis of birth registration and related socioeconomic factors, 9576 mother-child pairs were chosen from the data set of The Lao Social Indicator Survey 2011-12. After bivariate analysis with statistical tests including the chi-square test were conducted, logistic regression was performed to determine the variables that statistically influence accessibility to birth registration. Ethno-geographic factors and place of delivery were observed to be the factors associated with birth registration in this analysis. Many mothers in the Lao PDR deliver in their local communities. Therefore, capacity development of various human resources, such as Skilled Birth Attendant, to support the local administrative procedure of birth registration in their communities could be one option to overcoming the bottlenecks in the birth registration process in the Lao PDR.

  2. Evaluation of the use of registration stickers.

    Science.gov (United States)

    2011-04-01

    This research evaluated the potential costs and benefits of doing away with license plate registration stickers as part : of the registration renewal process for Pennsylvania. The research consisted of a comprehensive literature review, a : survey of...

  3. Minimally invasive registration for computer-assisted orthopedic surgery: combining tracked ultrasound and bone surface points via the P-IMLOP algorithm.

    Science.gov (United States)

    Billings, Seth; Kang, Hyun Jae; Cheng, Alexis; Boctor, Emad; Kazanzides, Peter; Taylor, Russell

    2015-06-01

    We present a registration method for computer-assisted total hip replacement (THR) surgery, which we demonstrate to improve the state of the art by both reducing the invasiveness of current methods and increasing registration accuracy. A critical element of computer-guided procedures is the determination of the spatial correspondence between the patient and a computational model of patient anatomy. The current method for establishing this correspondence in robot-assisted THR is to register points intraoperatively sampled by a tracked pointer from the exposed proximal femur and, via auxiliary incisions, from the distal femur. In this paper, we demonstrate a noninvasive technique for sampling points on the distal femur using tracked B-mode ultrasound imaging and present a new algorithm for registering these data called Projected Iterative Most-Likely Oriented Point (P-IMLOP). Points and normal orientations of the distal bone surface are segmented from ultrasound images and registered to the patient model along with points sampled from the exposed proximal femur via a tracked pointer. The proposed approach is evaluated using a bone- and tissue-mimicking leg phantom constructed to enable accurate assessment of experimental registration accuracy with respect to a CT-image-based model of the phantom. These experiments demonstrate that localization of the femur shaft is greatly improved by tracked ultrasound. The experiments further demonstrate that, for ultrasound-based data, the P-IMLOP algorithm significantly improves registration accuracy compared to the standard ICP algorithm. Registration via tracked ultrasound and the P-IMLOP algorithm has high potential to reduce the invasiveness and improve the registration accuracy of computer-assisted orthopedic procedures.

  4. A simplified controller and detailed dynamics of constant off-time peak current control

    Science.gov (United States)

    Van den Bossche, Alex; Dimitrova, Ekaterina; Valchev, Vencislav; Feradov, Firgan

    2017-09-01

    A fast and reliable current control is often the base of power electronic converters. The traditional constant frequency peak control is unstable above 50 % duty ratio. In contrast, the constant off-time peak current control (COTCC) is unconditionally stable and fast, so it is worth analyzing it. Another feature of the COTCC is that one can combine a current control together with a current protection. The time dynamics show a zero-transient response, even when the inductor changes in a wide range. It can also be modeled as a special transfer function for all frequencies. The article shows also that it can be implemented in a simple analog circuit using a wide temperature range IC, such as the LM2903, which is compatible with PV conversion and automotive temperature range. Experiments are done using a 3 kW step-up converter. A drawback is still that the principle does not easily fit in usual digital controllers up to now.

  5. Evaluation of linear registration algorithms for brain SPECT and the errors due to hypoperfusion lesions

    International Nuclear Information System (INIS)

    Radau, Perry E.; Slomka, Piotr J.; Julin, Per; Svensson, Leif; Wahlund, Lars-Olof

    2001-01-01

    The semiquantitative analysis of perfusion single-photon emission computed tomography (SPECT) images requires a reproducible, objective method. Automated spatial standardization (registration) of images is a prerequisite to this goal. A source of registration error is the presence of hypoperfusion defects, which was evaluated in this study with simulated lesions. The brain perfusion images measured by 99m Tc-HMPAO SPECT from 21 patients with probable Alzheimer's disease and 35 control subjects were retrospectively analyzed. An automatic segmentation method was developed to remove external activity. Three registration methods, robust least squares, normalized mutual information (NMI), and count difference were implemented and the effects of simulated defects were compared. The tested registration methods required segmentation of the cerebrum from external activity, and the automatic and manual methods differed by a three-dimensional displacement of 1.4±1.1 mm. NMI registration proved to be least adversely effected by simulated defects with 3 mm average displacement caused by severe defects. The error in quantifying the patient-template parietal ratio due to misregistration was 2.0% for large defects (70% hypoperfusion) and 0.5% for smaller defects (85% hypoperfusion)

  6. Fast Parallel Image Registration on CPU and GPU for Diagnostic Classification of Alzheimer's Disease

    Directory of Open Access Journals (Sweden)

    Denis P Shamonin

    2014-01-01

    Full Text Available Nonrigid image registration is an important, but time-consuming taskin medical image analysis. In typical neuroimaging studies, multipleimage registrations are performed, i.e. for atlas-based segmentationor template construction. Faster image registration routines wouldtherefore be beneficial.In this paper we explore acceleration of the image registrationpackage elastix by a combination of several techniques: iparallelization on the CPU, to speed up the cost function derivativecalculation; ii parallelization on the GPU building on andextending the OpenCL framework from ITKv4, to speed up the Gaussianpyramid computation and the image resampling step; iii exploitationof certain properties of the B-spline transformation model; ivfurther software optimizations.The accelerated registration tool is employed in a study ondiagnostic classification of Alzheimer's disease and cognitivelynormal controls based on T1-weighted MRI. We selected 299participants from the publicly available Alzheimer's DiseaseNeuroimaging Initiative database. Classification is performed with asupport vector machine based on gray matter volumes as a marker foratrophy. We evaluated two types of strategies (voxel-wise andregion-wise that heavily rely on nonrigid image registration.Parallelization and optimization resulted in an acceleration factorof 4-5x on an 8-core machine. Using OpenCL a speedup factor of ~2was realized for computation of the Gaussian pyramids, and 15-60 forthe resampling step, for larger images. The voxel-wise and theregion-wise classification methods had an area under thereceiver operator characteristic curve of 88% and 90%,respectively, both for standard and accelerated registration.We conclude that the image registration package elastix wassubstantially accelerated, with nearly identical results to thenon-optimized version. The new functionality will become availablein the next release of elastix as open source under the BSD license.

  7. Deformable image registration using convolutional neural networks

    Science.gov (United States)

    Eppenhof, Koen A. J.; Lafarge, Maxime W.; Moeskops, Pim; Veta, Mitko; Pluim, Josien P. W.

    2018-03-01

    Deformable image registration can be time-consuming and often needs extensive parameterization to perform well on a specific application. We present a step towards a registration framework based on a three-dimensional convolutional neural network. The network directly learns transformations between pairs of three-dimensional images. The outputs of the network are three maps for the x, y, and z components of a thin plate spline transformation grid. The network is trained on synthetic random transformations, which are applied to a small set of representative images for the desired application. Training therefore does not require manually annotated ground truth deformation information. The methodology is demonstrated on public data sets of inspiration-expiration lung CT image pairs, which come with annotated corresponding landmarks for evaluation of the registration accuracy. Advantages of this methodology are its fast registration times and its minimal parameterization.

  8. Behaviors study of image registration algorithms in image guided radiation therapy

    International Nuclear Information System (INIS)

    Zou Lian; Hou Qing

    2008-01-01

    Objective: Study the behaviors of image registration algorithms, and analyze the elements which influence the performance of image registrations. Methods: Pre-known corresponding coordinates were appointed for reference image and moving image, and then the influence of region of interest (ROI) selection, transformation function initial parameters and coupled parameter spaces on registration results were studied with a software platform developed in home. Results: Region of interest selection had a manifest influence on registration performance. An improperly chosen ROI resulted in a bad registration. Transformation function initial parameters selection based on pre-known information could improve the accuracy of image registration. Coupled parameter spaces would enhance the dependence of image registration algorithm on ROI selection. Conclusions: It is necessary for clinic IGRT to obtain a ROI selection strategy (depending on specific commercial software) correlated to tumor sites. Three suggestions for image registration technique developers are automatic selection of the initial parameters of transformation function based on pre-known information, developing specific image registration algorithm for specific image feature, and assembling real-time image registration algorithms according to tumor sites selected by software user. (authors)

  9. Avoiding Stair-Step Artifacts in Image Registration for GOES-R Navigation and Registration Assessment

    Science.gov (United States)

    Grycewicz, Thomas J.; Tan, Bin; Isaacson, Peter J.; De Luccia, Frank J.; Dellomo, John

    2016-01-01

    In developing software for independent verification and validation (IVV) of the Image Navigation and Registration (INR) capability for the Geostationary Operational Environmental Satellite R Series (GOES-R) Advanced Baseline Imager (ABI), we have encountered an image registration artifact which limits the accuracy of image offset estimation at the subpixel scale using image correlation. Where the two images to be registered have the same pixel size, subpixel image registration preferentially selects registration values where the image pixel boundaries are close to lined up. Because of the shape of a curve plotting input displacement to estimated offset, we call this a stair-step artifact. When one image is at a higher resolution than the other, the stair-step artifact is minimized by correlating at the higher resolution. For validating ABI image navigation, GOES-R images are correlated with Landsat-based ground truth maps. To create the ground truth map, the Landsat image is first transformed to the perspective seen from the GOES-R satellite, and then is scaled to an appropriate pixel size. Minimizing processing time motivates choosing the map pixels to be the same size as the GOES-R pixels. At this pixel size image processing of the shift estimate is efficient, but the stair-step artifact is present. If the map pixel is very small, stair-step is not a problem, but image correlation is computation-intensive. This paper describes simulation-based selection of the scale for truth maps for registering GOES-R ABI images.

  10. Intensity-based hierarchical elastic registration using approximating splines.

    Science.gov (United States)

    Serifovic-Trbalic, Amira; Demirovic, Damir; Cattin, Philippe C

    2014-01-01

    We introduce a new hierarchical approach for elastic medical image registration using approximating splines. In order to obtain the dense deformation field, we employ Gaussian elastic body splines (GEBS) that incorporate anisotropic landmark errors and rotation information. Since the GEBS approach is based on a physical model in form of analytical solutions of the Navier equation, it can very well cope with the local as well as global deformations present in the images by varying the standard deviation of the Gaussian forces. The proposed GEBS approximating model is integrated into the elastic hierarchical image registration framework, which decomposes a nonrigid registration problem into numerous local rigid transformations. The approximating GEBS registration scheme incorporates anisotropic landmark errors as well as rotation information. The anisotropic landmark localization uncertainties can be estimated directly from the image data, and in this case, they represent the minimal stochastic localization error, i.e., the Cramér-Rao bound. The rotation information of each landmark obtained from the hierarchical procedure is transposed in an additional angular landmark, doubling the number of landmarks in the GEBS model. The modified hierarchical registration using the approximating GEBS model is applied to register 161 image pairs from a digital mammogram database. The obtained results are very encouraging, and the proposed approach significantly improved all registrations comparing the mean-square error in relation to approximating TPS with the rotation information. On artificially deformed breast images, the newly proposed method performed better than the state-of-the-art registration algorithm introduced by Rueckert et al. (IEEE Trans Med Imaging 18:712-721, 1999). The average error per breast tissue pixel was less than 2.23 pixels compared to 2.46 pixels for Rueckert's method. The proposed hierarchical elastic image registration approach incorporates the GEBS

  11. Registration accuracy and quality of real-life images.

    Directory of Open Access Journals (Sweden)

    Wei-Yen Hsu

    Full Text Available BACKGROUND: A common registration problem for the application of consumer device is to align all the acquired image sequences into a complete scene. Image alignment requires a registration algorithm that will compensate as much as possible for geometric variability among images. However, images captured views from a real scene usually produce different distortions. Some are derived from the optic characteristics of image sensors, and others are caused by the specific scenes and objects. METHODOLOGY/PRINCIPAL FINDINGS: An image registration algorithm considering the perspective projection is proposed for the application of consumer devices in this study. It exploits a multiresolution wavelet-based method to extract significant features. An analytic differential approach is then proposed to achieve fast convergence of point matching. Finally, the registration accuracy is further refined to obtain subpixel precision by a feature-based modified Levenberg-Marquardt method. Due to its feature-based and nonlinear characteristic, it converges considerably faster than most other methods. In addition, vignette compensation and color difference adjustment are also performed to further improve the quality of registration results. CONCLUSIONS/SIGNIFICANCE: The performance of the proposed method is evaluated by testing the synthetic and real images acquired by a hand-held digital still camera and in comparison with two registration techniques in terms of the squared sum of intensity differences (SSD and correlation coefficient (CC. The results indicate that the proposed method is promising in registration accuracy and quality, which are statistically significantly better than other two approaches.

  12. Registration of FA and T1-weighted MRI data of healthy human brain based on template matching and normalized cross-correlation.

    Science.gov (United States)

    Malinsky, Milos; Peter, Roman; Hodneland, Erlend; Lundervold, Astri J; Lundervold, Arvid; Jan, Jiri

    2013-08-01

    In this work, we propose a new approach for three-dimensional registration of MR fractional anisotropy images with T1-weighted anatomy images of human brain. From the clinical point of view, this accurate coregistration allows precise detection of nerve fibers that is essential in neuroscience. A template matching algorithm combined with normalized cross-correlation was used for this registration task. To show the suitability of the proposed method, it was compared with the normalized mutual information-based B-spline registration provided by the Elastix software library, considered a reference method. We also propose a general framework for the evaluation of robustness and reliability of both registration methods. Both registration methods were tested by four evaluation criteria on a dataset consisting of 74 healthy subjects. The template matching algorithm has shown more reliable results than the reference method in registration of the MR fractional anisotropy and T1 anatomy image data. Significant differences were observed in the regions splenium of corpus callosum and genu of corpus callosum, considered very important areas of brain connectivity. We demonstrate that, in this registration task, the currently used mutual information-based parametric registration can be replaced by more accurate local template matching utilizing the normalized cross-correlation similarity measure.

  13. Deformable image registration using convolutional neural networks

    NARCIS (Netherlands)

    Eppenhof, Koen A.J.; Lafarge, Maxime W.; Moeskops, Pim; Veta, Mitko; Pluim, Josien P.W.

    2018-01-01

    Deformable image registration can be time-consuming and often needs extensive parameterization to perform well on a specific application. We present a step towards a registration framework based on a three-dimensional convolutional neural network. The network directly learns transformations between

  14. Comparison of Unmodulated Current Control Characteristics of Permanent Magnet Synchronous Motor

    Directory of Open Access Journals (Sweden)

    Anwar Muqorobin

    2014-12-01

    Full Text Available This paper discusses comparison of unmodulated current controls in PMSM, more specifically, on-off, sliding mode, predictive and hybrid controls. The purpose of this study is to select the most appropriate control technique to be adopted. The comparison method is preceded by modeling the motor and entering the values of the motor parameters. PI control is used for speed control and zero d-axis current is employed. Furthermore, performing simulation for each type ofthe selected current controls and analyzing their responses in terms of dq and abc currents, q-axis current response with step reference, as well as THD. Simulation results show that the on-off control gives the best overall performance based on its abc-axis current ripple and THD at large load torque. The hybrid control shows the best response occurring only at the fastest transient time of q-axis current but its response exhibits bad qualities compared with other controls. The predictive control yields the best responses offering the smallest d-axis ripple current and THD at small load torque condition. The sliding mode control, however, does not exhibit any prominent performance compared to the others. Results presented in this paper further indicate that for the PMSM used in the simulation the most appropriate control is the predictive control.

  15. GPU-based stochastic-gradient optimization for non-rigid medical image registration in time-critical applications

    NARCIS (Netherlands)

    Staring, M.; Al-Ars, Z.; Berendsen, Floris; Angelini, Elsa D.; Landman, Bennett A.

    2018-01-01

    Currently, non-rigid image registration algorithms are too computationally intensive to use in time-critical applications. Existing implementations that focus on speed typically address this by either parallelization on GPU-hardware, or by introducing methodically novel techniques into

  16. Convex Hull Aided Registration Method (CHARM).

    Science.gov (United States)

    Fan, Jingfan; Yang, Jian; Zhao, Yitian; Ai, Danni; Liu, Yonghuai; Wang, Ge; Wang, Yongtian

    2017-09-01

    Non-rigid registration finds many applications such as photogrammetry, motion tracking, model retrieval, and object recognition. In this paper we propose a novel convex hull aided registration method (CHARM) to match two point sets subject to a non-rigid transformation. First, two convex hulls are extracted from the source and target respectively. Then, all points of the point sets are projected onto the reference plane through each triangular facet of the hulls. From these projections, invariant features are extracted and matched optimally. The matched feature point pairs are mapped back onto the triangular facets of the convex hulls to remove outliers that are outside any relevant triangular facet. The rigid transformation from the source to the target is robustly estimated by the random sample consensus (RANSAC) scheme through minimizing the distance between the matched feature point pairs. Finally, these feature points are utilized as the control points to achieve non-rigid deformation in the form of thin-plate spline of the entire source point set towards the target one. The experimental results based on both synthetic and real data show that the proposed algorithm outperforms several state-of-the-art ones with respect to sampling, rotational angle, and data noise. In addition, the proposed CHARM algorithm also shows higher computational efficiency compared to these methods.

  17. The role of image registration in brain mapping

    Science.gov (United States)

    Toga, A.W.; Thompson, P.M.

    2008-01-01

    Image registration is a key step in a great variety of biomedical imaging applications. It provides the ability to geometrically align one dataset with another, and is a prerequisite for all imaging applications that compare datasets across subjects, imaging modalities, or across time. Registration algorithms also enable the pooling and comparison of experimental findings across laboratories, the construction of population-based brain atlases, and the creation of systems to detect group patterns in structural and functional imaging data. We review the major types of registration approaches used in brain imaging today. We focus on their conceptual basis, the underlying mathematics, and their strengths and weaknesses in different contexts. We describe the major goals of registration, including data fusion, quantification of change, automated image segmentation and labeling, shape measurement, and pathology detection. We indicate that registration algorithms have great potential when used in conjunction with a digital brain atlas, which acts as a reference system in which brain images can be compared for statistical analysis. The resulting armory of registration approaches is fundamental to medical image analysis, and in a brain mapping context provides a means to elucidate clinical, demographic, or functional trends in the anatomy or physiology of the brain. PMID:19890483

  18. Evaluation of Current Controllers for Distributed Power Generation Systems

    DEFF Research Database (Denmark)

    Timbus, Adrian; Liserre, Marco; Teodorescu, Remus

    2009-01-01

    This paper discusses the evaluation of different current controllers employed for grid-connected distributed power generation systems having variable input power, such as wind turbines and photovoltaic systems. The focus is mainly set on linear controllers such as proportional-integral, proportio......This paper discusses the evaluation of different current controllers employed for grid-connected distributed power generation systems having variable input power, such as wind turbines and photovoltaic systems. The focus is mainly set on linear controllers such as proportional......-integral, proportional-resonant, and deadbeat (DB) controllers. Additionally, an improved DB controller robust against grid impedance variation is also presented. Since the paper discusses the implementation of these controllers for grid-connected applications, their evaluation is made in three operating conditions....... First, in steady-state conditions, the contribution of controllers to the total harmonic distortion of the grid current is pursued. Further on, the behavior of controllers in the case of transient conditions like input power variations and grid voltage faults is also examined. Experimental results...

  19. Learning statistical correlation for fast prostate registration in image-guided radiotherapy

    International Nuclear Information System (INIS)

    Shi Yonghong; Liao Shu; Shen Dinggang

    2011-01-01

    Purpose: In adaptive radiation therapy of prostate cancer, fast and accurate registration between the planning image and treatment images of the patient is of essential importance. With the authors' recently developed deformable surface model, prostate boundaries in each treatment image can be rapidly segmented and their correspondences (or relative deformations) to the prostate boundaries in the planning image are also established automatically. However, the dense correspondences on the nonboundary regions, which are important especially for transforming the treatment plan designed in the planning image space to each treatment image space, are remained unresolved. This paper presents a novel approach to learn the statistical correlation between deformations of prostate boundary and nonboundary regions, for rapidly estimating deformations of the nonboundary regions when given the deformations of the prostate boundary at a new treatment image. Methods: The main contributions of the proposed method lie in the following aspects. First, the statistical deformation correlation will be learned from both current patient and other training patients, and further updated adaptively during the radiotherapy. Specifically, in the initial treatment stage when the number of treatment images collected from the current patient is small, the statistical deformation correlation is mainly learned from other training patients. As more treatment images are collected from the current patient, the patient-specific information will play a more important role in learning patient-specific statistical deformation correlation to effectively reflect prostate deformation of the current patient during the treatment. Eventually, only the patient-specific statistical deformation correlation is used to estimate dense correspondences when a sufficient number of treatment images have been acquired from the current patient. Second, the statistical deformation correlation will be learned by using a

  20. Multimodality image registration with software: state-of-the-art

    International Nuclear Information System (INIS)

    Slomka, Piotr J.; Baum, Richard P.

    2009-01-01

    Multimodality image integration of functional and anatomical data can be performed by means of dedicated hybrid imaging systems or by software image co-registration techniques. Hybrid positron emission tomography (PET)/computed tomography (CT) systems have found wide acceptance in oncological imaging, while software registration techniques have a significant role in patient-specific, cost-effective, and radiation dose-effective application of integrated imaging. Software techniques allow accurate (2-3 mm) rigid image registration of brain PET with CT and MRI. Nonlinear techniques are used in whole-body image registration, and recent developments allow for significantly accelerated computing times. Nonlinear software registration of PET with CT or MRI is required for multimodality radiation planning. Difficulties remain in the validation of nonlinear registration of soft tissue organs. The utilization of software-based multimodality image integration in a clinical environment is sometimes hindered by the lack of appropriate picture archiving and communication systems (PACS) infrastructure needed to efficiently and automatically integrate all available images into one common database. In cardiology applications, multimodality PET/single photon emission computed tomography and coronary CT angiography imaging is typically not required unless the results of one of the tests are equivocal. Software image registration is likely to be used in a complementary fashion with hybrid PET/CT or PET/magnetic resonance imaging systems. Software registration of stand-alone scans ''paved the way'' for the clinical application of hybrid scanners, demonstrating practical benefits of image integration before the hybrid dual-modality devices were available. (orig.)

  1. An enhanced block matching algorithm for fast elastic registration in adaptive radiotherapy

    International Nuclear Information System (INIS)

    Malsch, U; Thieke, C; Huber, P E; Bendl, R

    2006-01-01

    Image registration has many medical applications in diagnosis, therapy planning and therapy. Especially for time-adaptive radiotherapy, an efficient and accurate elastic registration of images acquired for treatment planning, and at the time of the actual treatment, is highly desirable. Therefore, we developed a fully automatic and fast block matching algorithm which identifies a set of anatomical landmarks in a 3D CT dataset and relocates them in another CT dataset by maximization of local correlation coefficients in the frequency domain. To transform the complete dataset, a smooth interpolation between the landmarks is calculated by modified thin-plate splines with local impact. The concept of the algorithm allows separate processing of image discontinuities like temporally changing air cavities in the intestinal track or rectum. The result is a fully transformed 3D planning dataset (planning CT as well as delineations of tumour and organs at risk) to a verification CT, allowing evaluation and, if necessary, changes of the treatment plan based on the current patient anatomy without time-consuming manual re-contouring. Typically the total calculation time is less than 5 min, which allows the use of the registration tool between acquiring the verification images and delivering the dose fraction for online corrections. We present verifications of the algorithm for five different patient datasets with different tumour locations (prostate, paraspinal and head-and-neck) by comparing the results with manually selected landmarks, visual assessment and consistency testing. It turns out that the mean error of the registration is better than the voxel resolution (2 x 2 x 3 mm 3 ). In conclusion, we present an algorithm for fully automatic elastic image registration that is precise and fast enough for online corrections in an adaptive fractionated radiation treatment course

  2. 76 FR 27898 - Registration and Recordation Program

    Science.gov (United States)

    2011-05-13

    ... to reflect a reorganization that has moved the Recordation function from the Visual Arts and... function from the Visual Arts and Recordation Division of the Registration and Recordation Program to the... Visual Arts Division of the Registration and Recordation Program, has been renamed the Recordation...

  3. On combining algorithms for deformable image registration

    NARCIS (Netherlands)

    Muenzing, S.E.A.; Ginneken, van B.; Pluim, J.P.W.; Dawant, B.M.

    2012-01-01

    We propose a meta-algorithm for registration improvement by combining deformable image registrations (MetaReg). It is inspired by a well-established method from machine learning, the combination of classifiers. MetaReg consists of two main components: (1) A strategy for composing an improved

  4. Numerical methods for image registration

    CERN Document Server

    Modersitzki, Jan

    2003-01-01

    Based on the author's lecture notes and research, this well-illustrated and comprehensive text is one of the first to provide an introduction to image registration with particular emphasis on numerical methods in medical imaging. Ideal for researchers in industry and academia, it is also a suitable study guide for graduate mathematicians, computer scientists, engineers, medical physicists, and radiologists.Image registration is utilised whenever information obtained from different viewpoints needs to be combined or compared and unwanted distortion needs to be eliminated. For example, CCTV imag

  5. The electronic system for mechanical oscillation parameters registration

    Directory of Open Access Journals (Sweden)

    Bulavin L. A.

    2008-08-01

    Full Text Available On the basis of the 8-bit microcontroller Microchip PIC16F630 the digital electronic device for harmonic oscillation parameters registration was developed. The device features are simple electric circuit and high operating speed (response time is less than 10 microseconds. The relevant software for the computer-controlled recording of harmonic oscillation parameters was designed. The device can be used as a part of the experimental setup for consistent fluids rheological parameters measurements.

  6. Adaptive slope compensation for high bandwidth digital current mode controller

    DEFF Research Database (Denmark)

    Taeed, Fazel; Nymand, Morten

    2015-01-01

    An adaptive slope compensation method for digital current mode control of dc-dc converters is proposed in this paper. The compensation slope is used for stabilizing the inner current loop in peak current mode control. In this method, the compensation slope is adapted with the variations...... in converter duty cycle. The adaptive slope compensation provides optimum controller operation in term of bandwidth over wide range of operating points. In this paper operation principle of the controller is discussed. The proposed controller is implemented in an FPGA to control a 100 W buck converter...

  7. Medical image registration algorithms assesment Bronze Standard application enactment on grids using the MOTEUR workflow engine

    CERN Document Server

    Glatard, T; Pennec, X

    2006-01-01

    Medical image registration is pre-processing needed for many medical image analysis procedures. A very large number of registration algorithms are available today, but their performance is often not known and very difficult to assess due to the lack of gold standard. The Bronze Standard algorithm is a very data and compute intensive statistical approach for quantifying registration algorithms accuracy. In this paper, we describe the Bronze Standard application and we discuss the need for grids to tackle such computations on medical image databases. We demonstrate MOTEUR, a service-based workflow engine optimized for dealing with data intensive applications. MOTEUR eases the enactment of the Bronze Standard and similar applications on the EGEE production grid infrastructure. It is a generic workflow engine, based on current standards and freely available, that can be used to instrument legacy application code at low cost.

  8. Three-dimensional measurement of small inner surface profiles using feature-based 3-D panoramic registration

    Science.gov (United States)

    Gong, Yuanzheng; Seibel, Eric J.

    2017-01-01

    Rapid development in the performance of sophisticated optical components, digital image sensors, and computer abilities along with decreasing costs has enabled three-dimensional (3-D) optical measurement to replace more traditional methods in manufacturing and quality control. The advantages of 3-D optical measurement, such as noncontact, high accuracy, rapid operation, and the ability for automation, are extremely valuable for inline manufacturing. However, most of the current optical approaches are eligible for exterior instead of internal surfaces of machined parts. A 3-D optical measurement approach is proposed based on machine vision for the 3-D profile measurement of tiny complex internal surfaces, such as internally threaded holes. To capture the full topographic extent (peak to valley) of threads, a side-view commercial rigid scope is used to collect images at known camera positions and orientations. A 3-D point cloud is generated with multiview stereo vision using linear motion of the test piece, which is repeated by a rotation to form additional point clouds. Registration of these point clouds into a complete reconstruction uses a proposed automated feature-based 3-D registration algorithm. The resulting 3-D reconstruction is compared with x-ray computed tomography to validate the feasibility of our proposed method for future robotically driven industrial 3-D inspection.

  9. Feature-Based Retinal Image Registration Using D-Saddle Feature

    Directory of Open Access Journals (Sweden)

    Roziana Ramli

    2017-01-01

    Full Text Available Retinal image registration is important to assist diagnosis and monitor retinal diseases, such as diabetic retinopathy and glaucoma. However, registering retinal images for various registration applications requires the detection and distribution of feature points on the low-quality region that consists of vessels of varying contrast and sizes. A recent feature detector known as Saddle detects feature points on vessels that are poorly distributed and densely positioned on strong contrast vessels. Therefore, we propose a multiresolution difference of Gaussian pyramid with Saddle detector (D-Saddle to detect feature points on the low-quality region that consists of vessels with varying contrast and sizes. D-Saddle is tested on Fundus Image Registration (FIRE Dataset that consists of 134 retinal image pairs. Experimental results show that D-Saddle successfully registered 43% of retinal image pairs with average registration accuracy of 2.329 pixels while a lower success rate is observed in other four state-of-the-art retinal image registration methods GDB-ICP (28%, Harris-PIIFD (4%, H-M (16%, and Saddle (16%. Furthermore, the registration accuracy of D-Saddle has the weakest correlation (Spearman with the intensity uniformity metric among all methods. Finally, the paired t-test shows that D-Saddle significantly improved the overall registration accuracy of the original Saddle.

  10. Balanced Current Control Strategy for Current Source Rectifier Stage of Indirect Matrix Converter under Unbalanced Grid Voltage Conditions

    Directory of Open Access Journals (Sweden)

    Yeongsu Bak

    2016-12-01

    Full Text Available This paper proposes a balanced current control strategy for the current source rectifier (CSR stage of an indirect matrix converter (IMC under unbalanced grid voltage conditions. If the three-phase grid connected to the voltage source inverter (VSI of the IMC has unbalanced voltage conditions, it affects the currents of the CSR stage and VSI stage, and the currents are distorted. Above all, the distorted currents of the CSR stage cause instability in the overall system, which can affect the life span of the system. Therefore, in this paper, a control strategy for balanced currents in the CSR stage is proposed. To achieve balanced currents in the CSR stage, the VSI stage should receive DC power without ripple components from the CSR stage. This is implemented by controlling the currents in the VSI stage. Therefore, the proposed control strategy decouples the positive and negative phase-sequence components existing in the unbalanced voltages and currents of the VSI stage. Using the proposed control strategy under unbalanced grid voltage conditions, the stability and life span of the overall system can be improved. The effectiveness of the proposed control strategy is verified by simulation and experimental results.

  11. 75 FR 49994 - James Stephen Ferguson, D.M.D.; Revocation of Registration

    Science.gov (United States)

    2010-08-16

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 09-64] James Stephen Ferguson, D.M.D.; Revocation of Registration On July 24, 2009, the Deputy Assistant Administrator, Office of Diversion Control, Drug Enforcement Administration (DEA), issued an Order to Show Cause to James Stephen...

  12. An efficient strategy based on an individualized selection of registration methods. Application to the coregistration of MR and SPECT images in neuro-oncology

    International Nuclear Information System (INIS)

    Tacchella, Jean-Marc; Lefort, Muriel; Habert, Marie-Odile; Yeni, Nathanaëlle; Kas, Aurélie; Frouin, Frédérique; Roullot, Elodie; Cohen, Mike-Ely; Guillevin, Rémy; Petrirena, Grégorio; Delattre, Jean-Yves

    2014-01-01

    An efficient registration strategy is described that aims to help solve delicate medical imaging registration problems. It consists of running several registration methods for each dataset and selecting the best one for each specific dataset, according to an evaluation criterion. Finally, the quality of the registration results, obtained with the best method, is visually scored by an expert as excellent, correct or poor. The strategy was applied to coregister Technetium-99m Sestamibi SPECT and MRI data in the framework of a follow-up protocol in patients with high grade gliomas receiving antiangiogenic therapy. To adapt the strategy to this clinical context, a robust semi-automatic evaluation criterion based on the physiological uptake of the Sestamibi tracer was defined. A panel of eighteen multimodal registration algorithms issued from BrainVisa, SPM or AIR software environments was systematically applied to the clinical database composed of sixty-two datasets. According to the expert visual validation, this new strategy provides 85% excellent registrations, 12% correct ones and only 3% poor ones. These results compare favorably to the ones obtained by the globally most efficient registration method over the whole database, for which only 61% of excellent registration results have been reported. Thus the registration strategy in its current implementation proves to be suitable for clinical application. (paper)

  13. Co-registration of the BNCT treatment planning images for clinical practice

    International Nuclear Information System (INIS)

    Salli, Eero; Seppaelae, Tiina; Kankaanranta, Leena; Asikainen, Sami; Savolainen, Sauli; Koivunoro, Hanna

    2006-01-01

    We have co-registered MRI, CT and FBPA-PET images for BNCT in clinical practice. Co-registration improves the spatial accuracy of the treatment planning by enabling use of information from all the co-registered modalities. The multimodal co-registration has been implemented as a service product provided by the Imaging Center of Helsinki University Central Hospital to other departments. To increase the accuracy of co-registration and patient positioning in the head area BNCT, a patient-specific fixation mask suitable for PET, MRI and CT was developed. The goal of the fixation mask is to normalize the orientation of the patient's head and neck. Co-registration is performed at the image processing unit by using a rigid body model, mutual-information based algorithms and partly in-house developed software tools. The accuracy of co-registration is verified by comparing the locations of the external skin markers and anatomical landmarks in different modalities. After co-registration, the images are transformed and covered into a format required by the BNCT dose-planning software and set to the dose-planning unit of the hospital. So far co-registration has been done for 22 patients. The co-registration protocol has proved to be reliable and efficient. Some registration errors are seen on some patients in the neck area because the rigid-body model used in co-registration is not fully valid for the brain-neck entity. The registration accuracy in this area could likely be improved by implementing a co-registration procedure utilizing a partly non-rigid body model. (author)

  14. Temadag om registrering/katalogisering til Web-katalogen

    DEFF Research Database (Denmark)

    Hansen, Hanne Hørl; Hammershøi, Lene

    2002-01-01

    Referat fra temadag om registrering/katalogisering til Web-katalogen afholdt af DFs Interessekreds for Registrering på RUC d. 13.marts 2002. Oplægsholdere fra Danmark og England gav deres bud på status og udviklingstendenser for arbejdet med at skabe og forbedre web-baserede bibliotekskataloger...

  15. 40 CFR 79.4 - Requirement of registration.

    Science.gov (United States)

    2010-07-01

    ... problem, however, a fuel manufacturer may use an additive that he has not previously reported provided... Section 79.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGISTRATION OF FUELS AND FUEL ADDITIVES General Provisions § 79.4 Requirement of registration. (a) Fuels. (1...

  16. Learning-Based Approaches to Deformable Image Registration

    NARCIS (Netherlands)

    Münzing, SEA

    2014-01-01

    Accurate registration of images is an important and often crucial step in many areas of image processing and analysis, yet it is only used in a small percentage of possible applications. Automated registration methods are not considered to be sufficiently robust to handle complex deformations and

  17. Dead Zone Oscillator Control for Communication-Free Synchronization of Paralleled, Three-Phase, Current-Controlled Inverters

    Science.gov (United States)

    2016-05-11

    Current-Controlled Inverters by Midshipman 1/C Spencer C. Shabshab, USN UNITED STATES NAVAL ACADEMY...Three-Phase, Current-Controlled Inverters by Midshipman 1/C Spencer C. Shabshab United States Naval Academy Annapolis, Maryland...for Communication-Free Synchronization of Paralleled, 5a. CONTRACT NUMBER Three-Phase, Current-Controlled Inverters 5b. GRANT NUMBER 5c

  18. ACIR: automatic cochlea image registration

    Science.gov (United States)

    Al-Dhamari, Ibraheem; Bauer, Sabine; Paulus, Dietrich; Lissek, Friedrich; Jacob, Roland

    2017-02-01

    Efficient Cochlear Implant (CI) surgery requires prior knowledge of the cochlea's size and its characteristics. This information helps to select suitable implants for different patients. To get these measurements, a segmentation method of cochlea medical images is needed. An important pre-processing step for good cochlea segmentation involves efficient image registration. The cochlea's small size and complex structure, in addition to the different resolutions and head positions during imaging, reveals a big challenge for the automated registration of the different image modalities. In this paper, an Automatic Cochlea Image Registration (ACIR) method for multi- modal human cochlea images is proposed. This method is based on using small areas that have clear structures from both input images instead of registering the complete image. It uses the Adaptive Stochastic Gradient Descent Optimizer (ASGD) and Mattes's Mutual Information metric (MMI) to estimate 3D rigid transform parameters. The use of state of the art medical image registration optimizers published over the last two years are studied and compared quantitatively using the standard Dice Similarity Coefficient (DSC). ACIR requires only 4.86 seconds on average to align cochlea images automatically and to put all the modalities in the same spatial locations without human interference. The source code is based on the tool elastix and is provided for free as a 3D Slicer plugin. Another contribution of this work is a proposed public cochlea standard dataset which can be downloaded for free from a public XNAT server.

  19. Simple shape space for 3D face registration

    Science.gov (United States)

    Košir, Andrej; Perkon, Igor; Bracun, Drago; Tasic, Jurij; Mozina, Janez

    2009-09-01

    Three dimensional (3D) face recognition is a topic getting increasing interest in biometric applications. In our research framework we developed a laser scanner that provides 3D cloud information and texture data. In a user scenario with cooperative subjects with indoor light conditions, we address three problems of 3D face biometrics: the face registration, the formulation of a shape space together with a special designed gradient algorithm and the impact of initial approximation to the convergence of a registration algorithm. By defining the face registration as a problem of aligning a 3D data cloud with a predefined reference template, we solve the registration problem with a second order gradient algorithm working on a shape space designed for reducing the computational complexity of the method.

  20. Current control of superconducting coils for fusion experimental facility

    International Nuclear Information System (INIS)

    Ise, T.; Etou, D.; Chikaraishi, H.; Takami, S.; Inoue, T.

    2003-01-01

    The LHD (Large Helical Device) has twelve superconducting coils and six dc power supplies, and following specifications are required for its control system; each coil current must be controlled independently, the steady state control error is less than 0.01% of the reference value, the current settling time for 0.1% of control error is less than 1 second, and the control system must be robust against turbulence caused by appearance and disappearance of the plasma, parameter errors and external electro-magnetic noises. In this paper, the design and test results of the coil current control system for the LHD are described. The good response and robustness are in the relation of trade off each other. H-infinity controller is one of schemes to guarantee robustness for stability. However, the independent responses of six coils were impossible by the H-infinity controller only. To resolve this problem, we applied a feed-forward control with the H-infinity control. Moreover, the advanced design method of H-infinity controller using μ-synthesis was applied to guarantee the control performance in the whole operating condition. As a result, good control results were obtained by experiments. (author)

  1. An automatic high precision registration method between large area aerial images and aerial light detection and ranging data

    Science.gov (United States)

    Du, Q.; Xie, D.; Sun, Y.

    2015-06-01

    The integration of digital aerial photogrammetry and Light Detetion And Ranging (LiDAR) is an inevitable trend in Surveying and Mapping field. We calculate the external orientation elements of images which identical with LiDAR coordinate to realize automatic high precision registration between aerial images and LiDAR data. There are two ways to calculate orientation elements. One is single image spatial resection using image matching 3D points that registered to LiDAR. The other one is Position and Orientation System (POS) data supported aerotriangulation. The high precision registration points are selected as Ground Control Points (GCPs) instead of measuring GCPs manually during aerotriangulation. The registration experiments indicate that the method which registering aerial images and LiDAR points has a great advantage in higher automation and precision compare with manual registration.

  2. Registration of indoor TLS data: in favor of a probabilistic approach initialized by geo-location

    International Nuclear Information System (INIS)

    Hullo, Jean-Francois

    2013-01-01

    Many pre-maintenance operations of industrial facilities currently resort on to three dimensional CAD models. The acquisition of these models is performed from point clouds measured by Terrestrial Laser Scanning (TLS). When the scenes are complex, several view points for scanning, also known as stations, are necessary to ensure the completeness and the density of the survey data. The generation of a global point cloud, i.e. the expression of all the acquired data in a common reference frame, is a crucial step called registration. During this process, the pose parameters are estimated. If the GNSS Systems are now a solution for many outdoor scenes, the registration of indoor TLS data still remains a challenge. The goal of this thesis is to improve the acquisition process of TLS data in industrial environments. The aim is to guarantee the precision and accuracy of acquired data, while optimizing on-site acquisition time and protocols by, as often as possible, freeing the operator from the constraints inherent to conventional topography surveys. In a first part, we consider the state of the art of the means and methods used during the acquisition of dense point clouds of complex interior scenes (Part I). In a second part, we study and evaluate the data available for the registration: terrestrial laser data, primitive reconstruction algorithms in point clouds and indoor geo-location Systems (Part II). In the third part, we then formalize and experiment a registration algorithm based on the use of matched primitives, reconstructed from per station point clouds ( Part III). We finally propose a probabilistic approach for matching primitives, allowing the integration of a priori information and uncertainty in the constraints System used for calculating poses (Part IV). The contributions of our work are as follows: - to take a critical look at current methods of TLS data acquisition in industrial environments, - to evaluate, through experimentations, the information

  3. 3-D brain image registration using optimal morphological processing

    International Nuclear Information System (INIS)

    Loncaric, S.; Dhawan, A.P.

    1994-01-01

    The three-dimensional (3-D) registration of Magnetic Resonance (MR) and Positron Emission Tomographic (PET) images of the brain is important for analysis of the human brain and its diseases. A procedure for optimization of (3-D) morphological structuring elements, based on a genetic algorithm, is presented in the paper. The registration of the MR and PET images is done by means of a registration procedure in two major phases. In the first phase, the Iterative Principal Axis Transform (IPAR) is used for initial registration. In the second phase, the optimal shape description method based on the Morphological Signature Transform (MST) is used for final registration. The morphological processing is used to improve the accuracy of the basic IPAR method. The brain ventricle is used as a landmark for MST registration. A near-optimal structuring element obtained by means of a genetic algorithm is used in MST to describe the shape of the ventricle. The method has been tested on the set of brain images demonstrating the feasibility of approach. (author). 11 refs., 3 figs

  4. Clinical trial registration in physical therapy journals: a cross-sectional study.

    Science.gov (United States)

    Babu, Abraham Samuel; Veluswamy, Sundar Kumar; Rao, Pratiksha Tilak; Maiya, Arun G

    2014-01-01

    Clinical trial registration has become an important part of editorial policies of various biomedical journals, including a few physical therapy journals. However, the extent to which editorial boards enforce the need for trial registration varies across journals. The purpose of this study was to identify editorial policies and reporting of trial registration details in MEDLINE-indexed English-language physical therapy journals. This study was carried out using a cross-sectional design. Editorial policies on trial registration of MEDLINE-indexed member journals of the International Society of Physiotherapy Journal Editors (ISPJE) (Journal of Geriatric Physical Therapy, Journal of Hand Therapy, Journal of Neurologic Physical Therapy, Journal of Orthopaedic and Sports Physical Therapy, Journal of Physiotherapy [formerly Australian Journal of Physiotherapy], Journal of Science and Medicine in Sport, Manual Therapy, Physical Therapy, Physical Therapy in Sport, Physiotherapy, Physiotherapy Research International, Physiotherapy Theory and Practice, and Revista Brasileira de Fisioterapia) were reviewed in April 2013. Full texts of reports of clinical trials published in these journals between January 1, 2008, and December 31, 2012, were independently assessed for information on trial registration. Among the 13 journals, 8 recommended trial registration, and 6 emphasized prospective trial registration. As of April 2013, 4,618 articles were published between January 2008 and December 2012, of which 9% (417) were clinical trials and 29% (121/417) of these reported trial registration details. A positive trend in reporting of trial registration was observed from 2008 to 2012. The study was limited to MEDLINE-indexed ISPJE member journals. Editorial policies on trial registration of physical therapy journals and a rising trend toward reporting of trial registration details indicate a positive momentum toward trial registration. Physical therapy journal editors need to show

  5. 21 CFR 607.26 - Amendments to establishment registration.

    Science.gov (United States)

    2010-04-01

    ... registration. Changes in individual ownership, corporate or partnership structure, location, or blood-product...) as an amendment to registration within 5 days of such changes. Changes in the names of officers and...

  6. Non-rigid point set registration of curves: registration of the superficial vessel centerlines of the brain

    Science.gov (United States)

    Marreiros, Filipe M. M.; Wang, Chunliang; Rossitti, Sandro; Smedby, Örjan

    2016-03-01

    In this study we present a non-rigid point set registration for 3D curves (composed by 3D set of points). The method was evaluated in the task of registration of 3D superficial vessels of the brain where it was used to match vessel centerline points. It consists of a combination of the Coherent Point Drift (CPD) and the Thin-Plate Spline (TPS) semilandmarks. The CPD is used to perform the initial matching of centerline 3D points, while the semilandmark method iteratively relaxes/slides the points. For the evaluation, a Magnetic Resonance Angiography (MRA) dataset was used. Deformations were applied to the extracted vessels centerlines to simulate brain bulging and sinking, using a TPS deformation where a few control points were manipulated to obtain the desired transformation (T1). Once the correspondences are known, the corresponding points are used to define a new TPS deformation(T2). The errors are measured in the deformed space, by transforming the original points using T1 and T2 and measuring the distance between them. To simulate cases where the deformed vessel data is incomplete, parts of the reference vessels were cut and then deformed. Furthermore, anisotropic normally distributed noise was added. The results show that the error estimates (root mean square error and mean error) are below 1 mm, even in the presence of noise and incomplete data.

  7. 15 CFR 296.7 - Joint venture registration.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Joint venture registration. 296.7 Section 296.7 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL... PROGRAM General § 296.7 Joint venture registration. Joint ventures selected for assistance under the...

  8. Multimodality image registration with software: state-of-the-art

    Energy Technology Data Exchange (ETDEWEB)

    Slomka, Piotr J. [Cedars-Sinai Medical Center, AIM Program/Department of Imaging, Los Angeles, CA (United States); University of California, David Geffen School of Medicine, Los Angeles, CA (United States); Baum, Richard P. [Center for PET, Department of Nuclear Medicine, Bad Berka (Germany)

    2009-03-15

    Multimodality image integration of functional and anatomical data can be performed by means of dedicated hybrid imaging systems or by software image co-registration techniques. Hybrid positron emission tomography (PET)/computed tomography (CT) systems have found wide acceptance in oncological imaging, while software registration techniques have a significant role in patient-specific, cost-effective, and radiation dose-effective application of integrated imaging. Software techniques allow accurate (2-3 mm) rigid image registration of brain PET with CT and MRI. Nonlinear techniques are used in whole-body image registration, and recent developments allow for significantly accelerated computing times. Nonlinear software registration of PET with CT or MRI is required for multimodality radiation planning. Difficulties remain in the validation of nonlinear registration of soft tissue organs. The utilization of software-based multimodality image integration in a clinical environment is sometimes hindered by the lack of appropriate picture archiving and communication systems (PACS) infrastructure needed to efficiently and automatically integrate all available images into one common database. In cardiology applications, multimodality PET/single photon emission computed tomography and coronary CT angiography imaging is typically not required unless the results of one of the tests are equivocal. Software image registration is likely to be used in a complementary fashion with hybrid PET/CT or PET/magnetic resonance imaging systems. Software registration of stand-alone scans ''paved the way'' for the clinical application of hybrid scanners, demonstrating practical benefits of image integration before the hybrid dual-modality devices were available. (orig.)

  9. Population based ranking of frameless CT-MRI registration methods

    Energy Technology Data Exchange (ETDEWEB)

    Opposits, Gabor; Kis, Sandor A.; Tron, Lajos; Emri, Miklos [Debrecen Univ. (Hungary). Dept. of Nuclear Medicine; Berenyi, Ervin [Debrecen Univ. (Hungary). Dept. of Biomedical Laboratory and Imaging Science; Takacs, Endre [Rotating Gamma Ltd., Debrecen (Hungary); Dobai, Jozsef G.; Bognar, Laszlo [Debrecen Univ., Medical Center (Hungary). Dept. of Neurosurgery; Szuecs, Bernadett [ScanoMed Ltd., Debrecen (Hungary)

    2015-07-01

    Clinical practice often requires simultaneous information obtained by two different imaging modalities. Registration algorithms are commonly used for this purpose. Automated procedures are very helpful in cases when the same kind of registration has to be performed on images of a high number of subjects. Radiotherapists would prefer to use the best automated method to assist therapy planning, however there are not accepted procedures for ranking the different registration algorithms. We were interested in developing a method to measure the population level performance of CT-MRI registration algorithms by a parameter of values in the [0,1] interval. Pairs of CT and MRI images were collected from 1051 subjects. Results of an automated registration were corrected manually until a radiologist and a neurosurgeon expert both accepted the result as good. This way 1051 registered MRI images were produced by the same pair of experts to be used as gold standards for the evaluation of the performance of other registration algorithms. Pearson correlation coefficient, mutual information, normalized mutual information, Kullback-Leibler divergence, L{sub 1} norm and square L{sub 2} norm (dis)similarity measures were tested for sensitivity to indicate the extent of (dis)similarity of a pair of individual mismatched images. The square Hellinger distance proved suitable to grade the performance of registration algorithms at population level providing the developers with a valuable tool to rank algorithms. The developed procedure provides an objective method to find the registration algorithm performing the best on the population level out of newly constructed or available preselected ones.

  10. Laser interrogation of latent vehicle registration number

    Energy Technology Data Exchange (ETDEWEB)

    Russo, R.E. [Lawrence Berkeley Lab., CA (United States). Energy and Environment Div.]|[Lawrence Livermore National Lab., CA (United States). Forensic Science Center; Pelkey, G.E. [City of Livermore Police Dept., CA (United States); Grant, P.; Whipple, R.E.; Andresen, B.D. [Lawrence Livermore National Lab., CA (United States). Forensic Science Center

    1994-09-01

    A recent investigation involved automobile registration numbers as important evidentiary specimens. In California, as in most states, small, thin metallic decals are issued to owners of vehicles each year as the registration is renewed. The decals are applied directly to the license plate of the vehicle and typically on top of the previous year`s expired decal. To afford some degree of security, the individual registration decals have been designed to tear easily; they cannot be separated from each other, but can be carefully removed intact from the metal license plate by using a razor blade. In September 1993, the City of Livermore Police Department obtained a blue 1993 California decal that had been placed over an orange 1992 decal. The two decals were being investigated as possible evidence in a case involving vehicle registration fraud. To confirm the suspicion and implicate a suspect, the department needed to known the registration number on the bottom (completely covered) 1992 decal. The authors attempted to use intense and directed light to interrogate the colored stickers. Optical illumination using a filtered white-light source partially identified the latent number. However, the most successful technique used a tunable dye laser pumped by a pulsed Nd:YAG laser. By selectively tuning the wavelength and intensity of the dye laser, backlit illumination of the decals permitted visualization of the underlying registration number through the surface of the top sticker. With optimally-tuned wavelength and intensity, 100% accuracy was obtained in identifying the sequence of latent characters. The advantage of optical techniques is their completely nondestructive nature, thus preserving the evidence for further interrogation or courtroom presentation.

  11. Pesticide Registration Information System

    Data.gov (United States)

    U.S. Environmental Protection Agency — PRISM provides an integrated, web portal for all pesticide related data, communications, registrations and transactions for OPP and its stakeholders, partners and...

  12. Validation of non-rigid point-set registration methods using a porcine bladder pelvic phantom

    Science.gov (United States)

    Zakariaee, Roja; Hamarneh, Ghassan; Brown, Colin J.; Spadinger, Ingrid

    2016-01-01

    The problem of accurate dose accumulation in fractionated radiotherapy treatment for highly deformable organs, such as bladder, has garnered increasing interest over the past few years. However, more research is required in order to find a robust and efficient solution and to increase the accuracy over the current methods. The purpose of this study was to evaluate the feasibility and accuracy of utilizing non-rigid (affine or deformable) point-set registration in accumulating dose in bladder of different sizes and shapes. A pelvic phantom was built to house an ex vivo porcine bladder with fiducial landmarks adhered onto its surface. Four different volume fillings of the bladder were used (90, 180, 360 and 480 cc). The performance of MATLAB implementations of five different methods were compared, in aligning the bladder contour point-sets. The approaches evaluated were coherent point drift (CPD), gaussian mixture model, shape context, thin-plate spline robust point matching (TPS-RPM) and finite iterative closest point (ICP-finite). The evaluation metrics included registration runtime, target registration error (TRE), root-mean-square error (RMS) and Hausdorff distance (HD). The reference (source) dataset was alternated through all four points-sets, in order to study the effect of reference volume on the registration outcomes. While all deformable algorithms provided reasonable registration results, CPD provided the best TRE values (6.4 mm), and TPS-RPM yielded the best mean RMS and HD values (1.4 and 6.8 mm, respectively). ICP-finite was the fastest technique and TPS-RPM, the slowest.

  13. Validation of non-rigid point-set registration methods using a porcine bladder pelvic phantom

    International Nuclear Information System (INIS)

    Zakariaee, Roja; Hamarneh, Ghassan; Brown, Colin J; Spadinger, Ingrid

    2016-01-01

    The problem of accurate dose accumulation in fractionated radiotherapy treatment for highly deformable organs, such as bladder, has garnered increasing interest over the past few years. However, more research is required in order to find a robust and efficient solution and to increase the accuracy over the current methods. The purpose of this study was to evaluate the feasibility and accuracy of utilizing non-rigid (affine or deformable) point-set registration in accumulating dose in bladder of different sizes and shapes. A pelvic phantom was built to house an ex vivo porcine bladder with fiducial landmarks adhered onto its surface. Four different volume fillings of the bladder were used (90, 180, 360 and 480 cc). The performance of MATLAB implementations of five different methods were compared, in aligning the bladder contour point-sets. The approaches evaluated were coherent point drift (CPD), gaussian mixture model, shape context, thin-plate spline robust point matching (TPS-RPM) and finite iterative closest point (ICP-finite). The evaluation metrics included registration runtime, target registration error (TRE), root-mean-square error (RMS) and Hausdorff distance (HD). The reference (source) dataset was alternated through all four points-sets, in order to study the effect of reference volume on the registration outcomes. While all deformable algorithms provided reasonable registration results, CPD provided the best TRE values (6.4 mm), and TPS-RPM yielded the best mean RMS and HD values (1.4 and 6.8 mm, respectively). ICP-finite was the fastest technique and TPS-RPM, the slowest. (paper)

  14. A Novel Technique for Prealignment in Multimodality Medical Image Registration

    Directory of Open Access Journals (Sweden)

    Wu Zhou

    2014-01-01

    Full Text Available Image pair is often aligned initially based on a rigid or affine transformation before a deformable registration method is applied in medical image registration. Inappropriate initial registration may compromise the registration speed or impede the convergence of the optimization algorithm. In this work, a novel technique was proposed for prealignment in both monomodality and multimodality image registration based on statistical correlation of gradient information. A simple and robust algorithm was proposed to determine the rotational differences between two images based on orientation histogram matching accumulated from local orientation of each pixel without any feature extraction. Experimental results showed that it was effective to acquire the orientation angle between two unregistered images with advantages over the existed method based on edge-map in multimodalities. Applying the orientation detection into the registration of CT/MR, T1/T2 MRI, and monomadality images with respect to rigid and nonrigid deformation improved the chances of finding the global optimization of the registration and reduced the search space of optimization.

  15. A semi-automated 2D/3D marker-based registration algorithm modelling prostate shrinkage during radiotherapy for prostate cancer

    International Nuclear Information System (INIS)

    Budiharto, Tom; Slagmolen, Pieter; Hermans, Jeroen; Maes, Frederik; Verstraete, Jan; Heuvel, Frank Van den; Depuydt, Tom; Oyen, Raymond; Haustermans, Karin

    2009-01-01

    Background and purpose: Currently, most available patient alignment tools based on implanted markers use manual marker matching and rigid registration transformations to measure the needed translational shifts. To quantify the particular effect of prostate gland shrinkage, implanted gold markers were tracked during a course of radiotherapy including an isotropic scaling factor to model prostate shrinkage. Materials and methods: Eight patients with prostate cancer had gold markers implanted transrectally and seven were treated with (neo) adjuvant androgen deprivation therapy. After patient alignment to skin tattoos, orthogonal electronic portal images (EPIs) were taken. A semi-automated 2D/3D marker-based registration was performed to calculate the necessary couch shifts. The registration consists of a rigid transformation combined with an isotropic scaling to model prostate shrinkage. Results: The inclusion of an isotropic shrinkage model in the registration algorithm cancelled the corresponding increase in registration error. The mean scaling factor was 0.89 ± 0.09. For all but two patients, a decrease of the isotropic scaling factor during treatment was observed. However, there was almost no difference in the translation offset between the manual matching of the EPIs to the digitally reconstructed radiographs and the semi-automated 2D/3D registration. A decrease in the intermarker distance was found correlating with prostate shrinkage rather than with random marker migration. Conclusions: Inclusion of shrinkage in the registration process reduces registration errors during a course of radiotherapy. Nevertheless, this did not lead to a clinically significant change in the proposed table translations when compared to translations obtained with manual marker matching without a scaling correction

  16. The ANACONDA algorithm for deformable image registration in radiotherapy

    International Nuclear Information System (INIS)

    Weistrand, Ola; Svensson, Stina

    2015-01-01

    Purpose: The purpose of this work was to describe a versatile algorithm for deformable image registration with applications in radiotherapy and to validate it on thoracic 4DCT data as well as CT/cone beam CT (CBCT) data. Methods: ANAtomically CONstrained Deformation Algorithm (ANACONDA) combines image information (i.e., intensities) with anatomical information as provided by contoured image sets. The registration problem is formulated as a nonlinear optimization problem and solved with an in-house developed solver, tailored to this problem. The objective function, which is minimized during optimization, is a linear combination of four nonlinear terms: 1. image similarity term; 2. grid regularization term, which aims at keeping the deformed image grid smooth and invertible; 3. a shape based regularization term which works to keep the deformation anatomically reasonable when regions of interest are present in the reference image; and 4. a penalty term which is added to the optimization problem when controlling structures are used, aimed at deforming the selected structure in the reference image to the corresponding structure in the target image. Results: To validate ANACONDA, the authors have used 16 publically available thoracic 4DCT data sets for which target registration errors from several algorithms have been reported in the literature. On average for the 16 data sets, the target registration error is 1.17 ± 0.87 mm, Dice similarity coefficient is 0.98 for the two lungs, and image similarity, measured by the correlation coefficient, is 0.95. The authors have also validated ANACONDA using two pelvic cases and one head and neck case with planning CT and daily acquired CBCT. Each image has been contoured by a physician (radiation oncologist) or experienced radiation therapist. The results are an improvement with respect to rigid registration. However, for the head and neck case, the sample set is too small to show statistical significance. Conclusions: ANACONDA

  17. Effectiveness of anodal transcranial direct current stimulation in patients with chronic low back pain: Design, method and protocol for a randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Luedtke Kerstin

    2011-12-01

    pain and whether it can further enhance the effects of a cognitive behavioural pain management programme. Trial registration: Current Controlled Trials ISRCTN89874874.

  18. Regulation and registration as drivers of continuous professional competence for Irish pre-hospital practitioners: a discussion paper.

    Science.gov (United States)

    Knox, S; Dunne, S S; Hughes, M; Cheeseman, S; Dunne, C P

    2016-05-01

    The regulatory body responsible for the registration of Irish pre-hospital practitioners, the Pre-Hospital Emergency Care Council (PHECC), identified the need to implement a continuing professional competence (CPC) framework. The first cycle of CPC (focused on emergency medical technicians) commenced in November 2013 creating for the first time a formal relationship between continuing competence and registration to practice. To review current literature and to describe benefits and challenges relevant to CPC, regulation, registration and their respective contributions to professionalism of pre-hospital practitioners: advanced paramedics, paramedics and emergency medical technicians. Online search of cumulative index to nursing and allied health literature (CINAHL Plus with Full Text), Allied and Complementary Medicine (AMED) and 'Pubmed' databases using: 'Continuous Professional Development'; 'Continuous Professional Development'; 'emergency medical technician'; 'paramedic'; 'registration'; 'regulation'; and "profession' for relevant articles published since 2004. Additional policy documents, discussion papers, and guidance documents were identified from bibliographies of papers found. Reports, governmental policies for other healthcare professions, and professional developments internationally for allied professions (e.g., nursing, physiotherapy and medicine) link maintenance of competence with requirements for registration to practice. We suggest that evolving professionalisation of Irish paramedics should be affirmed through behaviours and competencies that incorporate adherence to professional codes of conduct, reflective practice, and commitment to continuing professional development. While the need for ambulance practitioner CPD was identified in Ireland almost a decade ago, PHECC now has the opportunity to introduce a model of CPD for paramedics linking competence and professionalism to annual registration.

  19. High performance predictive current control of a three phase VSI: An ...

    Indian Academy of Sciences (India)

    ... current control of a three phase VSI: An experimental assessment ... Voltage source inverter; two level inverter; predictive current control; weighting factor ... Conventionally, for reference current tracking control in a two level VSI, the objective ...

  20. A Control Method of Current Type Matrix Converter for Plasma Control Coil Power Supply

    International Nuclear Information System (INIS)

    Shimada, K.; Matsukawa, M.; Kurihara, K.; Jun-ichi Itoh

    2006-01-01

    In exploration to a tokamak fusion reactor, the control of plasma instabilities of high β plasma such as neoclassical tearing mode (NTM), resistive wall mode (RWM) etc., is the key issue for steady-state sustainment. One of the proposed methods to avoid suppressing RWM is that AC current having a phase to work for reduction the RWM growth is generated in a coil (sector coil) equipped spirally on the plasma vacuum vessel. To stabilize RWM, precise and fast real-time feedback control of magnetic field with proper amplitude and frequency is necessary. This implies that an appropriate power supply dedicated for such an application is expected to be developed. A matrix converter as one of power supply candidates for this purpose could provide a solution The matrix converter, categorized in an AC/AC direct converter composed of nine bi-directional current switches, has a great feature that a large energy storage element is unnecessary in comparison with a standard existing AC/AC indirect converter, which is composed of an AC/DC converter and a DC/AC inverter. It is also advantageous in cost and size of its applications. Fortunately, a voltage type matrix converter has come to be available at the market recently, while a current type matrix converter, which is advantageous for fast control of the large-inductance coil current, has been unavailable. On the background above mentioned, we proposed a new current type matrix converter and its control method applicable to a power supply with fast response for suppressing plasma instabilities. Since this converter is required with high accuracy control, the gate control method is adopted to three-phase switching method using middle phase to reduce voltage and current waveforms distortion. The control system is composed of VME-bus board with DSP (Digital Signal Processor) and FPGA (Field Programmable Gate Array) for high speed calculation and control. This paper describes the control method of a current type matrix converter

  1. Interactive initialization of 2D/3D rigid registration

    Energy Technology Data Exchange (ETDEWEB)

    Gong, Ren Hui; Güler, Özgür [The Sheikh Zayed Institute for Pediatric Surgical Innovation, Children' s National Medical Center, Washington, DC 20010 (United States); Kürklüoglu, Mustafa [Department of Cardiac Surgery, Children' s National Medical Center, Washington, DC 20010 (United States); Lovejoy, John [Department of Orthopaedic Surgery and Sports Medicine, Children' s National Medical Center, Washington, DC 20010 (United States); Yaniv, Ziv, E-mail: ZYaniv@childrensnational.org [The Sheikh Zayed Institute for Pediatric Surgical Innovation, Children' s National Medical Center, Washington, DC 20010 and Departments of Pediatrics and Radiology, George Washington University, Washington, DC 20037 (United States)

    2013-12-15

    Purpose: Registration is one of the key technical components in an image-guided navigation system. A large number of 2D/3D registration algorithms have been previously proposed, but have not been able to transition into clinical practice. The authors identify the primary reason for the lack of adoption with the prerequisite for a sufficiently accurate initial transformation, mean target registration error of about 10 mm or less. In this paper, the authors present two interactive initialization approaches that provide the desired accuracy for x-ray/MR and x-ray/CT registration in the operating room setting. Methods: The authors have developed two interactive registration methods based on visual alignment of a preoperative image, MR, or CT to intraoperative x-rays. In the first approach, the operator uses a gesture based interface to align a volume rendering of the preoperative image to multiple x-rays. The second approach uses a tracked tool available as part of a navigation system. Preoperatively, a virtual replica of the tool is positioned next to the anatomical structures visible in the volumetric data. Intraoperatively, the physical tool is positioned in a similar manner and subsequently used to align a volume rendering to the x-ray images using an augmented reality (AR) approach. Both methods were assessed using three publicly available reference data sets for 2D/3D registration evaluation. Results: In the authors' experiments, the authors show that for x-ray/MR registration, the gesture based method resulted in a mean target registration error (mTRE) of 9.3 ± 5.0 mm with an average interaction time of 146.3 ± 73.0 s, and the AR-based method had mTREs of 7.2 ± 3.2 mm with interaction times of 44 ± 32 s. For x-ray/CT registration, the gesture based method resulted in a mTRE of 7.4 ± 5.0 mm with an average interaction time of 132.1 ± 66.4 s, and the AR-based method had mTREs of 8.3 ± 5.0 mm with interaction times of 58 ± 52 s. Conclusions: Based on

  2. Interactive initialization of 2D/3D rigid registration

    International Nuclear Information System (INIS)

    Gong, Ren Hui; Güler, Özgür; Kürklüoglu, Mustafa; Lovejoy, John; Yaniv, Ziv

    2013-01-01

    Purpose: Registration is one of the key technical components in an image-guided navigation system. A large number of 2D/3D registration algorithms have been previously proposed, but have not been able to transition into clinical practice. The authors identify the primary reason for the lack of adoption with the prerequisite for a sufficiently accurate initial transformation, mean target registration error of about 10 mm or less. In this paper, the authors present two interactive initialization approaches that provide the desired accuracy for x-ray/MR and x-ray/CT registration in the operating room setting. Methods: The authors have developed two interactive registration methods based on visual alignment of a preoperative image, MR, or CT to intraoperative x-rays. In the first approach, the operator uses a gesture based interface to align a volume rendering of the preoperative image to multiple x-rays. The second approach uses a tracked tool available as part of a navigation system. Preoperatively, a virtual replica of the tool is positioned next to the anatomical structures visible in the volumetric data. Intraoperatively, the physical tool is positioned in a similar manner and subsequently used to align a volume rendering to the x-ray images using an augmented reality (AR) approach. Both methods were assessed using three publicly available reference data sets for 2D/3D registration evaluation. Results: In the authors' experiments, the authors show that for x-ray/MR registration, the gesture based method resulted in a mean target registration error (mTRE) of 9.3 ± 5.0 mm with an average interaction time of 146.3 ± 73.0 s, and the AR-based method had mTREs of 7.2 ± 3.2 mm with interaction times of 44 ± 32 s. For x-ray/CT registration, the gesture based method resulted in a mTRE of 7.4 ± 5.0 mm with an average interaction time of 132.1 ± 66.4 s, and the AR-based method had mTREs of 8.3 ± 5.0 mm with interaction times of 58 ± 52 s. Conclusions: Based on the

  3. Improving transparency and reproducibility through registration: The status of intervention trials published in clinical psychology journals.

    Science.gov (United States)

    Cybulski, Lukasz; Mayo-Wilson, Evan; Grant, Sean

    2016-09-01

    Prospective registration increases the validity of randomized controlled trials (RCTs). In the United States, registration is a legal requirement for drugs and devices regulated by the Food and Drug Administration (FDA), and many biomedical journals refuse to publish trials that are not registered. Trials in clinical psychology have not been subject to these requirements; it is unknown to what extent they are registered. We searched the 25 highest-impact clinical psychology journals that published at least 1 RCT of a health-related psychological intervention in 2013. For included trials, we evaluated their registration status (prospective, retrospective, not registered) and the completeness of their outcome definitions. We identified 163 articles that reported 165 RCTs; 73 (44%) RCTs were registered, of which only 25 (15%) were registered prospectively. Of registered RCTs, only 42 (58%) indicated their registration status in the publication. Only 2 (1% of all trials) were registered prospectively and defined their primary outcomes completely. For the primary outcome(s), 72 (99%) of all registrations defined the domain, 67 (92%) the time frame, and 48 (66%) the specific measurements. Only 19 (26%) and 5 (7%) defined the specific metric and method of aggregation, respectively, for all primary outcomes. Very few reports of RCTs published in clinical psychology journals were registered prospectively and completely. Clinical psychology journals could improve transparency and reproducibility, as well as reduce bias, by requiring complete prospective trial registration for publication and by including trial registration numbers in all reports of RCTs. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  4. JALFHCC - Patient Registration Service

    Data.gov (United States)

    Department of Veterans Affairs — The Captain James A. Lovell Federal Health Care Center (JALFHCC) Patient Registration Service supports the operation of the first VA/Navy Federal Health Care Center...

  5. CT image registration in sinogram space.

    Science.gov (United States)

    Mao, Weihua; Li, Tianfang; Wink, Nicole; Xing, Lei

    2007-09-01

    Object displacement in a CT scan is generally reflected in CT projection data or sinogram. In this work, the direct relationship between object motion and the change of CT projection data (sinogram) is investigated and this knowledge is applied to create a novel algorithm for sinogram registration. Calculated and experimental results demonstrate that the registration technique works well for registering rigid 2D or 3D motion in parallel and fan beam samplings. Problem and solution for 3D sinogram-based registration of metallic fiducials are also addressed. Since the motion is registered before image reconstruction, the presented algorithm is particularly useful when registering images with metal or truncation artifacts. In addition, this algorithm is valuable for dealing with situations where only limited projection data are available, making it appealing for various applications in image guided radiation therapy.

  6. CT image registration in sinogram space

    International Nuclear Information System (INIS)

    Mao Weihua; Li Tianfang; Wink, Nicole; Xing Lei

    2007-01-01

    Object displacement in a CT scan is generally reflected in CT projection data or sinogram. In this work, the direct relationship between object motion and the change of CT projection data (sinogram) is investigated and this knowledge is applied to create a novel algorithm for sinogram registration. Calculated and experimental results demonstrate that the registration technique works well for registering rigid 2D or 3D motion in parallel and fan beam samplings. Problem and solution for 3D sinogram-based registration of metallic fiducials are also addressed. Since the motion is registered before image reconstruction, the presented algorithm is particularly useful when registering images with metal or truncation artifacts. In addition, this algorithm is valuable for dealing with situations where only limited projection data are available, making it appealing for various applications in image guided radiation therapy

  7. Current control of light by nonreciprocal magnetoplasmonics

    Energy Technology Data Exchange (ETDEWEB)

    Gong, Yongkang, E-mail: yongkang.gong@southwales.ac.uk; Li, Kang; Carver, Sara; Martinez, Juan Jose; Huang, Jungang; Copner, Nigel [Wireless and Optoelectronics Research and Innovation Centre (WORIC), Faculty of Computing, Engineering and Science, University of South Wales, Cardiff CF37 1DL (United Kingdom); Thueux, Yoann; Avlonitis, Nick [Airbus Group Innovations, Quadrant House, Celtic Springs, Coedkernew, NP10 8FZ Newport (United Kingdom)

    2015-05-11

    The ability to actively control light has long been a major scientific and technological goal. We proposed a scheme that allows for active control of light by utilizing the nonreciprocal magnetoplasmonic effect. As a proof of concept, we applied current signal through an ultrathin metallic film in a magneto-plasmonic multilayer and found that dynamic photonic nonreciprocity appears in magnetic-optical material layer due to the magnetic field being induced from current signal and modulates surface plasmon polaritons trapped in the metal surface and the light reflected. The proposed concept provides a possible way for the active control of light and could find potential applications such as ultrafast optoelectronic signal processing for plasmonic nanocircuit technology and ultrafast/large-aperture free-space electro-optic modulation platform for wireless laser communication technology.

  8. Automatic registration of terrestrial point cloud using panoramic reflectance images

    NARCIS (Netherlands)

    Kang, Z.

    2008-01-01

    Much attention is paid to registration of terrestrial point clouds nowadays. Research is carried out towards improved efficiency and automation of the registration process. This paper reports a new approach for point clouds registration utilizing reflectance panoramic images. The approach follows a

  9. Locally orderless registration

    DEFF Research Database (Denmark)

    Darkner, Sune; Sporring, Jon

    2013-01-01

    This paper presents a unifying approach for calculating a wide range of popular, but seemingly very different, similarity measures. Our domain is the registration of n-dimensional images sampled on a regular grid, and our approach is well suited for gradient-based optimization algorithms. Our app...

  10. Biomedical Image Registration

    DEFF Research Database (Denmark)

    This book constitutes the refereed proceedings of the 8th International Workshop on Biomedical Image Registration, WBIR 2018, held in Leiden, The Netherlands, in June 2018. The 11 full and poster papers included in this volume were carefully reviewed and selected from 17 submitted papers. The pap...

  11. Mitigation of grid-current distortion for LCL-filtered grid-connected voltage-source inverter with inverter-side current control

    DEFF Research Database (Denmark)

    Xin, Zhen; Mattavelli, Paolo; Yao, WenLi

    2017-01-01

    Due to the low inductance of an LCL-filter, the grid current generated by an LCL-filtered Voltage Source Inverter (VSI) is sensitive to low-order grid-voltage harmonics. This issue is especially tough for the control system with Inverter Current Feedback (ICF), because the grid-current harmonics...... can freely flow into the filter capacitor without control. To cope with this issue, this paper develops an approach for the ICF control system to suppress the grid-current harmonics without adding extra sensors. The proposed method applies harmonic controllers and feedforward scheme simultaneously...

  12. 4D ultrasound and 3D MRI registration of beating heart

    International Nuclear Information System (INIS)

    Herlambang, N.; Matsumiya, K.; Masamune, K.; Dohi, T.; Liao, H.; Tsukihara, H.; Takamoto, S.

    2007-01-01

    To realize intra-cardiac surgery without cardio-pulmonary bypass, a medical imaging technique with both high image quality and data acquisition rate that is fast enough to follow heart beat movements is required. In this research, we proposed a method that utilized the image quality of MRI and the speed of ultrasound. We developed a 4D image reconstruction method using image registration of 3D MRI and 4D ultrasound images. The registration method consists of rigid registration between 3D MRI and 3D ultrasound with the same heart beat phase, and non-rigid registration between 3D ultrasound images from different heart beat phases. Non-rigid registration was performed with B-spline based registration using variable spring model. In phantom experiment using balloon phantom, registration accuracy was less than 2 mm for total heart volume variation range of 10%. We applied our registration method on 3D MRI and 4D ultrasound images of a volunteer's beating heart data and confirmed through visual observation that heart beat pattern was well reproduced. (orig.)

  13. Robust linear registration of CT images using random regression forests

    Science.gov (United States)

    Konukoglu, Ender; Criminisi, Antonio; Pathak, Sayan; Robertson, Duncan; White, Steve; Haynor, David; Siddiqui, Khan

    2011-03-01

    Global linear registration is a necessary first step for many different tasks in medical image analysis. Comparing longitudinal studies1, cross-modality fusion2, and many other applications depend heavily on the success of the automatic registration. The robustness and efficiency of this step is crucial as it affects all subsequent operations. Most common techniques cast the linear registration problem as the minimization of a global energy function based on the image intensities. Although these algorithms have proved useful, their robustness in fully automated scenarios is still an open question. In fact, the optimization step often gets caught in local minima yielding unsatisfactory results. Recent algorithms constrain the space of registration parameters by exploiting implicit or explicit organ segmentations, thus increasing robustness4,5. In this work we propose a novel robust algorithm for automatic global linear image registration. Our method uses random regression forests to estimate posterior probability distributions for the locations of anatomical structures - represented as axis aligned bounding boxes6. These posterior distributions are later integrated in a global linear registration algorithm. The biggest advantage of our algorithm is that it does not require pre-defined segmentations or regions. Yet it yields robust registration results. We compare the robustness of our algorithm with that of the state of the art Elastix toolbox7. Validation is performed via 1464 pair-wise registrations in a database of very diverse 3D CT images. We show that our method decreases the "failure" rate of the global linear registration from 12.5% (Elastix) to only 1.9%.

  14. On the nature of data collection for soft-tissue image-to-physical organ registration: a noise characterization study

    Science.gov (United States)

    Collins, Jarrod A.; Heiselman, Jon S.; Weis, Jared A.; Clements, Logan W.; Simpson, Amber L.; Jarnagin, William R.; Miga, Michael I.

    2017-03-01

    In image-guided liver surgery (IGLS), sparse representations of the anterior organ surface may be collected intraoperatively to drive image-to-physical space registration. Soft tissue deformation represents a significant source of error for IGLS techniques. This work investigates the impact of surface data quality on current surface based IGLS registration methods. In this work, we characterize the robustness of our IGLS registration methods to noise in organ surface digitization. We study this within a novel human-to-phantom data framework that allows a rapid evaluation of clinically realistic data and noise patterns on a fully characterized hepatic deformation phantom. Additionally, we implement a surface data resampling strategy that is designed to decrease the impact of differences in surface acquisition. For this analysis, n=5 cases of clinical intraoperative data consisting of organ surface and salient feature digitizations from open liver resection were collected and analyzed within our human-to-phantom validation framework. As expected, results indicate that increasing levels of noise in surface acquisition cause registration fidelity to deteriorate. With respect to rigid registration using the raw and resampled data at clinically realistic levels of noise (i.e. a magnitude of 1.5 mm), resampling improved TRE by 21%. In terms of nonrigid registration, registrations using resampled data outperformed the raw data result by 14% at clinically realistic levels and were less susceptible to noise across the range of noise investigated. These results demonstrate the types of analyses our novel human-to-phantom validation framework can provide and indicate the considerable benefits of resampling strategies.

  15. [Multimodal medical image registration using cubic spline interpolation method].

    Science.gov (United States)

    He, Yuanlie; Tian, Lianfang; Chen, Ping; Wang, Lifei; Ye, Guangchun; Mao, Zongyuan

    2007-12-01

    Based on the characteristic of the PET-CT multimodal image series, a novel image registration and fusion method is proposed, in which the cubic spline interpolation method is applied to realize the interpolation of PET-CT image series, then registration is carried out by using mutual information algorithm and finally the improved principal component analysis method is used for the fusion of PET-CT multimodal images to enhance the visual effect of PET image, thus satisfied registration and fusion results are obtained. The cubic spline interpolation method is used for reconstruction to restore the missed information between image slices, which can compensate for the shortage of previous registration methods, improve the accuracy of the registration, and make the fused multimodal images more similar to the real image. Finally, the cubic spline interpolation method has been successfully applied in developing 3D-CRT (3D Conformal Radiation Therapy) system.

  16. Performance evaluation of grid-enabled registration algorithms using bronze-standards

    CERN Document Server

    Glatard, T; Montagnat, J

    2006-01-01

    Evaluating registration algorithms is difficult due to the lack of gold standard in most clinical procedures. The bronze standard is a real-data based statistical method providing an alternative registration reference through a computationally intensive image database registration procedure. We propose in this paper an efficient implementation of this method through a grid-interfaced workflow enactor enabling the concurrent processing of hundreds of image registrations in a couple of hours only. The performances of two different grid infrastructures were compared. We computed the accuracy of 4 different rigid registration algorithms on longitudinal MRI images of brain tumors. Results showed an average subvoxel accuracy of 0.4 mm and 0.15 degrees in rotation.

  17. Consistency of parametric registration in serial MRI studies of brain tumor progression

    International Nuclear Information System (INIS)

    Mang, Andreas; Buzug, Thorsten M.; Schnabel, Julia A.; Crum, William R.; Modat, Marc; Ourselin, Sebastien; Hawkes, David J.; Camara-Rey, Oscar; Palm, Christoph; Caseiras, Gisele Brasil; Jaeger, H.R.

    2008-01-01

    The consistency of parametric registration in multi-temporal magnetic resonance (MR) imaging studies was evaluated. Serial MRI scans of adult patients with a brain tumor (glioma) were aligned by parametric registration. The performance of low-order spatial alignment (6/9/12 degrees of freedom) of different 3D serial MR-weighted images is evaluated. A registration protocol for the alignment of all images to one reference coordinate system at baseline is presented. Registration results were evaluated for both, multimodal intra-timepoint and mono-modal multi-temporal registration. The latter case might present a challenge to automatic intensity-based registration algorithms due to ill-defined correspondences. The performance of our algorithm was assessed by testing the inverse registration consistency. Four different similarity measures were evaluated to assess consistency. Careful visual inspection suggests that images are well aligned, but their consistency may be imperfect. Sub-voxel inconsistency within the brain was found for allsimilarity measures used for parametric multi-temporal registration. T1-weighted images were most reliable for establishing spatial correspondence between different timepoints. The parametric registration algorithm is feasible for use in this application. The sub-voxel resolution mean displacement error of registration transformations demonstrates that the algorithm converges to an almost identical solution for forward and reverse registration. (orig.)

  18. Accelerating Neuroimage Registration through Parallel Computation of Similarity Metric.

    Directory of Open Access Journals (Sweden)

    Yun-Gang Luo

    Full Text Available Neuroimage registration is crucial for brain morphometric analysis and treatment efficacy evaluation. However, existing advanced registration algorithms such as FLIRT and ANTs are not efficient enough for clinical use. In this paper, a GPU implementation of FLIRT with the correlation ratio (CR as the similarity metric and a GPU accelerated correlation coefficient (CC calculation for the symmetric diffeomorphic registration of ANTs have been developed. The comparison with their corresponding original tools shows that our accelerated algorithms can greatly outperform the original algorithm in terms of computational efficiency. This paper demonstrates the great potential of applying these registration tools in clinical applications.

  19. 75 FR 52737 - Pesticide Product Registrations; Unconditional and Conditional Approvals

    Science.gov (United States)

    2010-08-27

    ...: Plasma Neem Oil Biological insecticide, EPA Registration Number 84185-4 for use on several food and non...) of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), of registrations for pesticide... the end of the relevant registration approval summary using the instructions provided under FOR...

  20. Evaluation of whole-body MR to CT deformable image registration

    NARCIS (Netherlands)

    Akbarzadeh, A.; Gutierrez, D.; Baskin, A.; Ay, M. R.; Ahmadian, A.; Alam, N. Riahi; Loevblad, K. O.; Zaidi, H.

    2013-01-01

    Multimodality image registration plays a crucial role in various clinical and research applications. The aim of this study is to present an optimized MR to CT whole-body deformable image registration algorithm and its validation using clinical studies. A 3D intermodality registration technique based

  1. Expert Talks: Understanding civil registration and vital statistics ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2017-09-13

    Sep 13, 2017 ... What are CRVS systems and why do they matter? ... Cambodia cleared civil registration backlogs by providing free, time-bound registration. ... IDRC supports results-based research that has real impacts on the ground and ...

  2. Bayesian estimation of regularization and atlas building in diffeomorphic image registration.

    Science.gov (United States)

    Zhang, Miaomiao; Singh, Nikhil; Fletcher, P Thomas

    2013-01-01

    This paper presents a generative Bayesian model for diffeomorphic image registration and atlas building. We develop an atlas estimation procedure that simultaneously estimates the parameters controlling the smoothness of the diffeomorphic transformations. To achieve this, we introduce a Monte Carlo Expectation Maximization algorithm, where the expectation step is approximated via Hamiltonian Monte Carlo sampling on the manifold of diffeomorphisms. An added benefit of this stochastic approach is that it can successfully solve difficult registration problems involving large deformations, where direct geodesic optimization fails. Using synthetic data generated from the forward model with known parameters, we demonstrate the ability of our model to successfully recover the atlas and regularization parameters. We also demonstrate the effectiveness of the proposed method in the atlas estimation problem for 3D brain images.

  3. Serial volumetric registration of pulmonary CT studies

    Science.gov (United States)

    Silva, José Silvestre; Silva, Augusto; Sousa Santos, Beatriz

    2008-03-01

    Detailed morphological analysis of pulmonary structures and tissue, provided by modern CT scanners, is of utmost importance as in the case of oncological applications both for diagnosis, treatment, and follow-up. In this case, a patient may go through several tomographic studies throughout a period of time originating volumetric sets of image data that must be appropriately registered in order to track suspicious radiological findings. The structures or regions of interest may change their position or shape in CT exams acquired at different moments, due to postural, physiologic or pathologic changes, so, the exams should be registered before any follow-up information can be extracted. Postural mismatching throughout time is practically impossible to avoid being particularly evident when imaging is performed at the limiting spatial resolution. In this paper, we propose a method for intra-patient registration of pulmonary CT studies, to assist in the management of the oncological pathology. Our method takes advantage of prior segmentation work. In the first step, the pulmonary segmentation is performed where trachea and main bronchi are identified. Then, the registration method proceeds with a longitudinal alignment based on morphological features of the lungs, such as the position of the carina, the pulmonary areas, the centers of mass and the pulmonary trans-axial principal axis. The final step corresponds to the trans-axial registration of the corresponding pulmonary masked regions. This is accomplished by a pairwise sectional registration process driven by an iterative search of the affine transformation parameters leading to optimal similarity metrics. Results with several cases of intra-patient, intra-modality registration, up to 7 time points, show that this method provides accurate registration which is needed for quantitative tracking of lesions and the development of image fusion strategies that may effectively assist the follow-up process.

  4. Registration status and outcome reporting of trials published in core headache medicine journals.

    Science.gov (United States)

    Rayhill, Melissa L; Sharon, Roni; Burch, Rebecca; Loder, Elizabeth

    2015-11-17

    To evaluate randomized controlled trial (RCT) registration and outcome reporting compliance in core headache medicine journals. We identified RCTs published in core journals (Headache, Cephalalgia, and the Journal of Headache and Pain) from 2005 through 2014. We searched articles for trial registration numbers, which were verified in the corresponding trial registry. We categorized trial funding sources as industry, academic, government, or mixed. We contacted corresponding authors to assess reasons for nonregistration. We evaluated whether primary outcomes in trial registries matched those in corresponding publications. The journals published 225 RCTs over the study period. Fifty-eight of 225 (26%) reported a trial registration number in the article that could be linked to a corresponding registry entry. Trial registration rates increased over the 9 years of the study. Forty-six of 118 (39%) of industry-funded studies were registered compared with 27% of academic and 0% of government-funded studies. Only 5% of RCTs were prospectively registered, reported primary outcomes identical to those in the trial registry, and did not report unacknowledged post hoc outcomes. The most common reason for nonregistration was lack of awareness. Only about a quarter of the articles published in the core headache medicine journals are compliant with trial registration, but compliance has increased over time. Selective reporting of outcomes remains a problem, and very few trials met all 3 reporting standards assessed in this study. Efforts to improve the quality of trial reporting in the headache literature should continue. © 2015 American Academy of Neurology.

  5. Groupwise registration of MR brain images with tumors

    Science.gov (United States)

    Tang, Zhenyu; Wu, Yihong; Fan, Yong

    2017-09-01

    A novel groupwise image registration framework is developed for registering MR brain images with tumors. Our method iteratively estimates a normal-appearance counterpart for each tumor image to be registered and constructs a directed graph (digraph) of normal-appearance images to guide the groupwise image registration. Particularly, our method maps each tumor image to its normal appearance counterpart by identifying and inpainting brain tumor regions with intensity information estimated using a low-rank plus sparse matrix decomposition based image representation technique. The estimated normal-appearance images are groupwisely registered to a group center image guided by a digraph of images so that the total length of ‘image registration paths’ to be the minimum, and then the original tumor images are warped to the group center image using the resulting deformation fields. We have evaluated our method based on both simulated and real MR brain tumor images. The registration results were evaluated with overlap measures of corresponding brain regions and average entropy of image intensity information, and Wilcoxon signed rank tests were adopted to compare different methods with respect to their regional overlap measures. Compared with a groupwise image registration method that is applied to normal-appearance images estimated using the traditional low-rank plus sparse matrix decomposition based image inpainting, our method achieved higher image registration accuracy with statistical significance (p  =  7.02  ×  10-9).

  6. Harmonic Mitigation Using a Polarized Ramp-time Current-Controlled Inverter

    Directory of Open Access Journals (Sweden)

    Lawrence J. Borle

    2010-12-01

    Full Text Available This paper describes the implementation of a shunt active power filter for a three-phase four-wire system to compensate for power quality problems generated by mixed non-linear loads, which are a combination of harmonic, reactive and unbalanced components. The filter is a three-phase current-controlled voltage source inverter (CC-VSI with a filter inductor at the AC output and a DC-bus capacitor. The CC-VSI is operated to directly control the grid current to be sinusoidal and in phase with the grid voltage without sensing the load currents. The switching is controlled using polarized ramp-time current control, which is based on the concept of zero average current error (ZACE with a fixed switching frequency. The laboratory experiment results indicate that the filter is able to mitigate predominantly the harmonics, as well as the reactive power, so that the grid currents are sinusoidal, in phase with the grid voltages and symmetrical although the grid voltage contains harmonics.

  7. Fast free-form deformable registration via calculus of variations

    International Nuclear Information System (INIS)

    Lu Weiguo; Chen Mingli; Olivera, Gustavo H; Ruchala, Kenneth J; Mackie, Thomas R

    2004-01-01

    In this paper, we present a fully automatic, fast and accurate deformable registration technique. This technique deals with free-form deformation. It minimizes an energy functional that combines both similarity and smoothness measures. By using calculus of variations, the minimization problem was represented as a set of nonlinear elliptic partial differential equations (PDEs). A Gauss-Seidel finite difference scheme is used to iteratively solve the PDE. The registration is refined by a multi-resolution approach. The whole process is fully automatic. It takes less than 3 min to register two three-dimensional (3D) image sets of size 256 x 256 x 61 using a single 933 MHz personal computer. Extensive experiments are presented. These experiments include simulations, phantom studies and clinical image studies. Experimental results show that our model and algorithm are suited for registration of temporal images of a deformable body. The registration of inspiration and expiration phases of the lung images shows that the method is able to deal with large deformations. When applied to the daily CT images of a prostate patient, the results show that registration based on iterative refinement of displacement field is appropriate to describe the local deformations in the prostate and the rectum. Similarity measures improved significantly after the registration. The target application of this paper is for radiotherapy treatment planning and evaluation that incorporates internal organ deformation throughout the course of radiation therapy. The registration method could also be equally applied in diagnostic radiology

  8. Feasibility of Multimodal Deformable Registration for Head and Neck Tumor Treatment Planning

    Energy Technology Data Exchange (ETDEWEB)

    Fortunati, Valerio, E-mail: v.fortunati@erasmusmc.nl [Biomedical Imaging Group Rotterdam, Department of Medical Informatics and Radiology, Erasmus MC University Medical Center, Rotterdam (Netherlands); Verhaart, René F. [Hyperthermia Unit, Department of Radiation Oncology, Erasmus MC University Medical Center Cancer Institute, Rotterdam (Netherlands); Angeloni, Francesco [Istituto di Ricovero e Cura a Carattere Scientifico Foundation SDN for Research and High Education in Nuclear Diagnostics, Naples (Italy); Lugt, Aad van der [Department of Radiology, Erasmus MC University Medical Center, Rotterdam (Netherlands); Niessen, Wiro J. [Biomedical Imaging Group Rotterdam, Department of Medical Informatics and Radiology, Erasmus MC University Medical Center, Rotterdam (Netherlands); Faculty of Applied Sciences, Delft University of Technology, Delft (Netherlands); Veenland, Jifke F. [Biomedical Imaging Group Rotterdam, Department of Medical Informatics and Radiology, Erasmus MC University Medical Center, Rotterdam (Netherlands); Paulides, Margarethus M. [Hyperthermia Unit, Department of Radiation Oncology, Erasmus MC University Medical Center Cancer Institute, Rotterdam (Netherlands); Walsum, Theo van [Biomedical Imaging Group Rotterdam, Department of Medical Informatics and Radiology, Erasmus MC University Medical Center, Rotterdam (Netherlands)

    2014-09-01

    Purpose: To investigate the feasibility of using deformable registration in clinical practice to fuse MR and CT images of the head and neck for treatment planning. Method and Materials: A state-of-the-art deformable registration algorithm was optimized, evaluated, and compared with rigid registration. The evaluation was based on manually annotated anatomic landmarks and regions of interest in both modalities. We also developed a multiparametric registration approach, which simultaneously aligns T1- and T2-weighted MR sequences to CT. This was evaluated and compared with single-parametric approaches. Results: Our results show that deformable registration yielded a better accuracy than rigid registration, without introducing unrealistic deformations. For deformable registration, an average landmark alignment of approximatively 1.7 mm was obtained. For all the regions of interest excluding the cerebellum and the parotids, deformable registration provided a median modified Hausdorff distance of approximatively 1 mm. Similar accuracies were obtained for the single-parameter and multiparameter approaches. Conclusions: This study demonstrates that deformable registration of head-and-neck CT and MR images is feasible, with overall a significanlty higher accuracy than for rigid registration.

  9. Feasibility of Multimodal Deformable Registration for Head and Neck Tumor Treatment Planning

    International Nuclear Information System (INIS)

    Fortunati, Valerio; Verhaart, René F.; Angeloni, Francesco; Lugt, Aad van der; Niessen, Wiro J.; Veenland, Jifke F.; Paulides, Margarethus M.; Walsum, Theo van

    2014-01-01

    Purpose: To investigate the feasibility of using deformable registration in clinical practice to fuse MR and CT images of the head and neck for treatment planning. Method and Materials: A state-of-the-art deformable registration algorithm was optimized, evaluated, and compared with rigid registration. The evaluation was based on manually annotated anatomic landmarks and regions of interest in both modalities. We also developed a multiparametric registration approach, which simultaneously aligns T1- and T2-weighted MR sequences to CT. This was evaluated and compared with single-parametric approaches. Results: Our results show that deformable registration yielded a better accuracy than rigid registration, without introducing unrealistic deformations. For deformable registration, an average landmark alignment of approximatively 1.7 mm was obtained. For all the regions of interest excluding the cerebellum and the parotids, deformable registration provided a median modified Hausdorff distance of approximatively 1 mm. Similar accuracies were obtained for the single-parameter and multiparameter approaches. Conclusions: This study demonstrates that deformable registration of head-and-neck CT and MR images is feasible, with overall a significanlty higher accuracy than for rigid registration

  10. Discrete Current Control Strategy of Permanent Magnet Synchronous Motors

    Directory of Open Access Journals (Sweden)

    Yan Dong

    2013-01-01

    Full Text Available A control strategy of permanent magnet synchronous motors (PMSMs, which is different from the traditional vector control (VC and direct torque control (DTC, is proposed. Firstly, the circular rotating magnetic field is analyzed on the simplified model and discredited into stepping magnetic field. The stepping magnetomotive force will drive the rotor to run as the stepping motor. Secondly, the stator current orientation is used to build the control model instead of rotor flux orientation. Then, the discrete current control strategy is set and adopted in positioning control. Three methods of the strategy are simulated in computer and tested on the experiment platform of PMSM. The control precision is also verified through the experiment.

  11. Registration for public drug benefits across areas of differing ethnic composition in British Columbia, Canada.

    Science.gov (United States)

    Leong, Vivian W; Morgan, Steve; Wong, Sabrina T; Hanley, Gillian E; Black, Charlyn

    2010-06-17

    In 2003, the government of British Columbia, Canada introduced a universal drug benefit plan to cover drug costs that are high relative to household income. Residents were required to register in order to be eligible for the income-based benefits. Given past research suggesting that registration processes may pose an access barrier to certain subpopulations, we aimed to determine whether registration rates varied across small geographic areas that differed in ethnic composition. Using linked population-based administrative databases and census data, we conducted multivariate logistic regression analyses to determine whether the probability of registration for the public drug plan varied across areas of differing ethnic composition, controlling for household-level predisposing, enabling and needs factors. The adjusted odds of registration did not differ across regions characterized by high concentrations (greater than 30%) of residents identifying as North American, British, French or other European. Households located in areas with concentrations of residents identifying as an Asian ethnicity had the highest odds of program registration: Chinese (OR = 1.21, CI: 1.19-1.23) and South Asian (OR = 1.19, CI: 1.16-1.22). Despite this positive finding, households residing in areas with relatively high concentrations of recent immigrants had slightly lower adjusted odds of registering for the program (OR = 0.97, CI: 0.95-0.98). This study identified ethnic variation in registration for a new public drug benefit program in British Columbia. However, unlike previous studies, the variation observed did not indicate that areas with high concentrations of certain ethnicities experienced disadvantages. Potential explanations are discussed.

  12. Registration of 3D Face Scans with Average Face Models

    NARCIS (Netherlands)

    A.A. Salah (Albert Ali); N. Alyuz; L. Akarun

    2008-01-01

    htmlabstractThe accuracy of a 3D face recognition system depends on a correct registration that aligns the facial surfaces and makes a comparison possible. The best results obtained so far use a costly one-to-all registration approach, which requires the registration of each facial surface to all

  13. Mitigation of Grid Current Distortion for LCL-Filtered Voltage Source Inverter with Inverter Current Feedback Control

    DEFF Research Database (Denmark)

    Xin, Zhen; Mattavelli, Paolo; Yao, WenLi

    2018-01-01

    LCL filters feature low inductance; thus, the injected grid current from an LCL-filtered Voltage Source Inverter (VSI) can be easily distorted by grid voltage harmonics. This problem is especially tough for the control system with Inverter-side Current Feedback (ICF), since the grid current...... harmonics can freely flow into the filter capacitor. In this case, because of the loss of harmonic information, traditional harmonic controllers fail to mitigate the grid current distortion. Although this problem may be avoided using the grid voltage feedforward scheme, the required differentiators may...

  14. Supervised local error estimation for nonlinear image registration using convolutional neural networks

    NARCIS (Netherlands)

    Eppenhof, Koen A.J.; Pluim, Josien P.W.; Styner, M.A.; Angelini, E.D.

    2017-01-01

    Error estimation in medical image registration is valuable when validating, comparing, or combining registration methods. To validate a nonlinear image registration method, ideally the registration error should be known for the entire image domain. We propose a supervised method for the estimation

  15. The One to Multiple Automatic High Accuracy Registration of Terrestrial LIDAR and Optical Images

    Science.gov (United States)

    Wang, Y.; Hu, C.; Xia, G.; Xue, H.

    2018-04-01

    The registration of ground laser point cloud and close-range image is the key content of high-precision 3D reconstruction of cultural relic object. In view of the requirement of high texture resolution in the field of cultural relic at present, The registration of point cloud and image data in object reconstruction will result in the problem of point cloud to multiple images. In the current commercial software, the two pairs of registration of the two kinds of data are realized by manually dividing point cloud data, manual matching point cloud and image data, manually selecting a two - dimensional point of the same name of the image and the point cloud, and the process not only greatly reduces the working efficiency, but also affects the precision of the registration of the two, and causes the problem of the color point cloud texture joint. In order to solve the above problems, this paper takes the whole object image as the intermediate data, and uses the matching technology to realize the automatic one-to-one correspondence between the point cloud and multiple images. The matching of point cloud center projection reflection intensity image and optical image is applied to realize the automatic matching of the same name feature points, and the Rodrigo matrix spatial similarity transformation model and weight selection iteration are used to realize the automatic registration of the two kinds of data with high accuracy. This method is expected to serve for the high precision and high efficiency automatic 3D reconstruction of cultural relic objects, which has certain scientific research value and practical significance.

  16. Mid-space-independent deformable image registration.

    Science.gov (United States)

    Aganj, Iman; Iglesias, Juan Eugenio; Reuter, Martin; Sabuncu, Mert Rory; Fischl, Bruce

    2017-05-15

    Aligning images in a mid-space is a common approach to ensuring that deformable image registration is symmetric - that it does not depend on the arbitrary ordering of the input images. The results are, however, generally dependent on the mathematical definition of the mid-space. In particular, the set of possible solutions is typically restricted by the constraints that are enforced on the transformations to prevent the mid-space from drifting too far from the native image spaces. The use of an implicit atlas has been proposed as an approach to mid-space image registration. In this work, we show that when the atlas is aligned to each image in the native image space, the data term of implicit-atlas-based deformable registration is inherently independent of the mid-space. In addition, we show that the regularization term can be reformulated independently of the mid-space as well. We derive a new symmetric cost function that only depends on the transformation morphing the images to each other, rather than to the atlas. This eliminates the need for anti-drift constraints, thereby expanding the space of allowable deformations. We provide an implementation scheme for the proposed framework, and validate it through diffeomorphic registration experiments on brain magnetic resonance images. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. 75 FR 65667 - Lincoln Pharmacy; Revocation of Registration

    Science.gov (United States)

    2010-10-26

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Lincoln Pharmacy; Revocation of Registration... Order to Show Cause and Immediate Suspension of Registration (Order) to Lincoln Pharmacy (Respondent... pharmacy located at 52 Lincoln Highway, Edison, New Jersey, which is owned and operated by Mr. Vincent Hsia...

  18. New Approaches to Circulating Current Controllers for Modular Multilevel Converters

    Directory of Open Access Journals (Sweden)

    Miguel Moranchel

    2017-01-01

    Full Text Available In the next years, modular multilevel converters (MMCs are going to be a next generation multilevel converters for medium to high voltage conversion applications, such as medium voltage motor drives, medium voltage flexible AC transmission systems (FACTS and high voltage direct current transmission. They provide advantages such as high modularity, availability, low generation of harmonics, etc. However, the circulating current distorts the leg currents and increases the rated current of power devices, which further increases system cost. This paper focuses on analysis and suppression of these currents in a MMC using two algorithms for tracking of harmonics. For this work resonant controllers and repetitive controllers have been selected. Both controllers are analyzed and simulations results are presented. Moreover, the controllers have been tested and validated for a three phase MMC operating as an inverter using a real processing platform based on Zynq by Xilinx and designed to control large multilevel converters and in a real MMC prototype. These results are provided to demonstrate the feasibility of the proposed method.

  19. Fast and accurate registration of cranial CT images with A-mode ultrasound.

    Science.gov (United States)

    Fieten, Lorenz; Schmieder, Kirsten; Engelhardt, Martin; Pasalic, Lamija; Radermacher, Klaus; Heger, Stefan

    2009-05-01

    Within the CRANIO project, a navigation module based on preoperative computed tomography (CT) data was developed for Computer and Robot Assisted Neurosurgery. The approach followed for non-invasive user-interactive registration of cranial CT images with the physical operating space consists of surface-based registration following pre-registration based on anatomical landmarks. Surface-based registration relies on bone surface points digitized transcutaneously by means of an optically tracked A-mode ultrasound (US) probe. As probe alignment and thus bone surface point digitization may be time-consuming, we investigated how to obtain high registration accuracy despite inaccurate pre-registration and a limited number of digitized bone surface points. Furthermore, we aimed at efficient man-machine-interaction during the probe alignment process. Finally, we addressed the problem of registration plausibility estimation in our approach. We modified the Iterative Closest Point (ICP) algorithm, presented by Besl and McKay and frequently used for surface-based registration, such that it can escape from local minima of the cost function to be iteratively minimized. The random-based ICP (R-ICP) we developed is less influenced by the quality of the pre-registration as it can escape from local minima close to the starting point for iterative optimization in the 6D domain of rigid transformations. The R-ICP is also better suited to approximate the global minimum as it can escape from local minima in the vicinity of the global minimum, too. Furthermore, we developed both CT-less and CT-based probe alignment tools along with appropriate man-machine strategies for a more time-efficient palpation process. To improve registration reliability, we developed a simple plausibility test based on data readily available after registration. In a cadaver study, where we evaluated the R-ICP algorithm, the probe alignment tools, and the plausibility test, the R-ICP algorithm consistently

  20. Improving Intensity-Based Lung CT Registration Accuracy Utilizing Vascular Information

    Directory of Open Access Journals (Sweden)

    Kunlin Cao

    2012-01-01

    Full Text Available Accurate pulmonary image registration is a challenging problem when the lungs have a deformation with large distance. In this work, we present a nonrigid volumetric registration algorithm to track lung motion between a pair of intrasubject CT images acquired at different inflation levels and introduce a new vesselness similarity cost that improves intensity-only registration. Volumetric CT datasets from six human subjects were used in this study. The performance of four intensity-only registration algorithms was compared with and without adding the vesselness similarity cost function. Matching accuracy was evaluated using landmarks, vessel tree, and fissure planes. The Jacobian determinant of the transformation was used to reveal the deformation pattern of local parenchymal tissue. The average matching error for intensity-only registration methods was on the order of 1 mm at landmarks and 1.5 mm on fissure planes. After adding the vesselness preserving cost function, the landmark and fissure positioning errors decreased approximately by 25% and 30%, respectively. The vesselness cost function effectively helped improve the registration accuracy in regions near thoracic cage and near the diaphragm for all the intensity-only registration algorithms tested and also helped produce more consistent and more reliable patterns of regional tissue deformation.

  1. Diffusion Maps for Multimodal Registration

    Directory of Open Access Journals (Sweden)

    Gemma Piella

    2014-06-01

    Full Text Available Multimodal image registration is a difficult task, due to the significant intensity variations between the images. A common approach is to use sophisticated similarity measures, such as mutual information, that are robust to those intensity variations. However, these similarity measures are computationally expensive and, moreover, often fail to capture the geometry and the associated dynamics linked with the images. Another approach is the transformation of the images into a common space where modalities can be directly compared. Within this approach, we propose to register multimodal images by using diffusion maps to describe the geometric and spectral properties of the data. Through diffusion maps, the multimodal data is transformed into a new set of canonical coordinates that reflect its geometry uniformly across modalities, so that meaningful correspondences can be established between them. Images in this new representation can then be registered using a simple Euclidean distance as a similarity measure. Registration accuracy was evaluated on both real and simulated brain images with known ground-truth for both rigid and non-rigid registration. Results showed that the proposed approach achieved higher accuracy than the conventional approach using mutual information.

  2. A multicore based parallel image registration method.

    Science.gov (United States)

    Yang, Lin; Gong, Leiguang; Zhang, Hong; Nosher, John L; Foran, David J

    2009-01-01

    Image registration is a crucial step for many image-assisted clinical applications such as surgery planning and treatment evaluation. In this paper we proposed a landmark based nonlinear image registration algorithm for matching 2D image pairs. The algorithm was shown to be effective and robust under conditions of large deformations. In landmark based registration, the most important step is establishing the correspondence among the selected landmark points. This usually requires an extensive search which is often computationally expensive. We introduced a nonregular data partition algorithm using the K-means clustering algorithm to group the landmarks based on the number of available processing cores. The step optimizes the memory usage and data transfer. We have tested our method using IBM Cell Broadband Engine (Cell/B.E.) platform.

  3. WE-H-202-04: Advanced Medical Image Registration Techniques

    International Nuclear Information System (INIS)

    Christensen, G.

    2016-01-01

    Deformable image registration has now been commercially available for several years, with solid performance in a number of sites and for several applications including contour and dose mapping. However, more complex applications have arisen, such as assessing response to radiation therapy over time, registering images pre- and post-surgery, and auto-segmentation from atlases. These applications require innovative registration algorithms to achieve accurate alignment. The goal of this session is to highlight emerging registration technology and these new applications. The state of the art in image registration will be presented from an engineering perspective. Translational clinical applications will also be discussed to tie these new registration approaches together with imaging and radiation therapy applications in specific diseases such as cervical and lung cancers. Learning Objectives: To understand developing techniques and algorithms in deformable image registration that are likely to translate into clinical tools in the near future. To understand emerging imaging and radiation therapy clinical applications that require such new registration algorithms. Research supported in part by the National Institutes of Health under award numbers P01CA059827, R01CA166119, and R01CA166703. Disclosures: Phillips Medical systems (Hugo), Roger Koch (Christensen) support, Varian Medical Systems (Brock), licensing agreements from Raysearch (Brock) and Varian (Hugo).; K. Brock, Licensing Agreement - RaySearch Laboratories. Research Funding - Varian Medical Systems; G. Hugo, Research grant from National Institutes of Health, award number R01CA166119.; G. Christensen, Research support from NIH grants CA166119 and CA166703 and a gift from Roger Koch. There are no conflicts of interest.

  4. WE-H-202-04: Advanced Medical Image Registration Techniques

    Energy Technology Data Exchange (ETDEWEB)

    Christensen, G. [University of Iowa (United States)

    2016-06-15

    Deformable image registration has now been commercially available for several years, with solid performance in a number of sites and for several applications including contour and dose mapping. However, more complex applications have arisen, such as assessing response to radiation therapy over time, registering images pre- and post-surgery, and auto-segmentation from atlases. These applications require innovative registration algorithms to achieve accurate alignment. The goal of this session is to highlight emerging registration technology and these new applications. The state of the art in image registration will be presented from an engineering perspective. Translational clinical applications will also be discussed to tie these new registration approaches together with imaging and radiation therapy applications in specific diseases such as cervical and lung cancers. Learning Objectives: To understand developing techniques and algorithms in deformable image registration that are likely to translate into clinical tools in the near future. To understand emerging imaging and radiation therapy clinical applications that require such new registration algorithms. Research supported in part by the National Institutes of Health under award numbers P01CA059827, R01CA166119, and R01CA166703. Disclosures: Phillips Medical systems (Hugo), Roger Koch (Christensen) support, Varian Medical Systems (Brock), licensing agreements from Raysearch (Brock) and Varian (Hugo).; K. Brock, Licensing Agreement - RaySearch Laboratories. Research Funding - Varian Medical Systems; G. Hugo, Research grant from National Institutes of Health, award number R01CA166119.; G. Christensen, Research support from NIH grants CA166119 and CA166703 and a gift from Roger Koch. There are no conflicts of interest.

  5. Frequency-Controlled Current-Fed Resonant Converter with No Input Ripple Current

    Directory of Open Access Journals (Sweden)

    Bor-Ren Lin

    2018-02-01

    Full Text Available This paper studies a frequency-controlled current-fed resonant circuit. The adopted direct current (DC-to-DC converter contains two boost circuits and a resonant circuit on the primary side. First, two boost circuits are connected in parallel to achieve voltage step-up and reduce input ripple current by using interleaved pulse-width modulation. Therefore, the size and current rating of boost inductors are decreased in the proposed converter. Second, the boost voltage is connected to the resonant circuit to realize the mechanism of the zero-voltage switching of all active switches and zero-current switching of all diodes. Two boost circuits and a resonant circuit use the same power devices in order to lessen the switch counts. The voltage doubler topology is adopted on the secondary side (high-voltage side. Therefore, the voltage rating of diodes on the high-voltage side is clamped at output voltage. The feasibility of the studied circuit is confirmed by the experimental tests with a 1 kW prototype circuit.

  6. Automatic segmentation of phase-correlated CT scans through nonrigid image registration using geometrically regularized free-form deformation

    International Nuclear Information System (INIS)

    Shekhar, Raj; Lei, Peng; Castro-Pareja, Carlos R.; Plishker, William L.; D'Souza, Warren D.

    2007-01-01

    Conventional radiotherapy is planned using free-breathing computed tomography (CT), ignoring the motion and deformation of the anatomy from respiration. New breath-hold-synchronized, gated, and four-dimensional (4D) CT acquisition strategies are enabling radiotherapy planning utilizing a set of CT scans belonging to different phases of the breathing cycle. Such 4D treatment planning relies on the availability of tumor and organ contours in all phases. The current practice of manual segmentation is impractical for 4D CT, because it is time consuming and tedious. A viable solution is registration-based segmentation, through which contours provided by an expert for a particular phase are propagated to all other phases while accounting for phase-to-phase motion and anatomical deformation. Deformable image registration is central to this task, and a free-form deformation-based nonrigid image registration algorithm will be presented. Compared with the original algorithm, this version uses novel, computationally simpler geometric constraints to preserve the topology of the dense control-point grid used to represent free-form deformation and prevent tissue fold-over. Using mean squared difference as an image similarity criterion, the inhale phase is registered to the exhale phase of lung CT scans of five patients and of characteristically low-contrast abdominal CT scans of four patients. In addition, using expert contours for the inhale phase, the corresponding contours were automatically generated for the exhale phase. The accuracy of the segmentation (and hence deformable image registration) was judged by comparing automatically segmented contours with expert contours traced directly in the exhale phase scan using three metrics: volume overlap index, root mean square distance, and Hausdorff distance. The accuracy of the segmentation (in terms of radial distance mismatch) was approximately 2 mm in the thorax and 3 mm in the abdomen, which compares favorably to the

  7. A hybrid biomechanical intensity based deformable image registration of lung 4DCT

    International Nuclear Information System (INIS)

    Samavati, Navid; Velec, Michael; Brock, Kristy

    2015-01-01

    Deformable image registration (DIR) has been extensively studied over the past two decades due to its essential role in many image-guided interventions (IGI). IGI demands a highly accurate registration that maintains its accuracy across the entire region of interest. This work evaluates the improvement in accuracy and consistency by refining the results of Morfeus, a biomechanical model-based DIR algorithm.A hybrid DIR algorithm is proposed based on, a biomechanical model–based DIR algorithm and a refinement step based on a B-spline intensity-based algorithm. Inhale and exhale reconstructions of four-dimensional computed tomography (4DCT) lung images from 31 patients were initially registered using the biomechanical DIR by modeling contact surface between the lungs and the chest cavity. The resulting deformations were then refined using the intensity-based algorithm to reduce any residual uncertainties. Important parameters in the intensity-based algorithm, including grid spacing, number of pyramids, and regularization coefficient, were optimized on 10 randomly-chosen patients (out of 31). Target registration error (TRE) was calculated by measuring the Euclidean distance of common anatomical points on both images after registration. For each patient a minimum of 30 points/lung were used.Grid spacing of 8 mm, 5 levels of grid pyramids, and regularization coefficient of 3.0 were found to provide optimal results on 10 randomly chosen patients. Overall the entire patient population (n = 31), the hybrid method resulted in mean ± SD (90th%) TRE of 1.5 ± 1.4 (2.9) mm compared to 3.1 ± 1.9 (5.6) using biomechanical DIR and 2.6 ± 2.5 (6.1) using intensity-based DIR alone.The proposed hybrid biomechanical modeling intensity based algorithm is a promising DIR technique which could be used in various IGI procedures. The current investigation shows the efficacy of this approach for the registration of 4DCT images of the lungs with average accuracy of 1.5

  8. Some Registral Features of Matrimonial Advertisement in Indian English

    Science.gov (United States)

    Mehrotra, R. R.

    1975-01-01

    Examines these distinct registral features of matrimonial newspaper advertisements in English in India: incongruity, deletion of preposition, miscellaneous deletions, two-word sentence, new abbreviations, registral confusion, stylistic variation. (RM)

  9. 76 FR 4072 - Registration of Claims of Copyright

    Science.gov (United States)

    2011-01-24

    ... of published photographs should contact the Visual Arts Division for permission and guidance on... online registration has been available for basic registration claims, it has not yet been made generally... is registered is primarily photographic in nature. In fact, the Visual Arts Division has accepted...

  10. 75 FR 44655 - Registration of Mortgage Loan Originators

    Science.gov (United States)

    2010-07-28

    ... State licensing and registration must be accomplished through the same online registration system, the... noting that the exceptions should not be structured to benefit only small institutions. \\1\\ 12 U.S.C... gaming opportunities essentially unrealistic. Many commenters noted the complexity of the proposed...

  11. 76 FR 6185 - Registration of Mortgage Loan Originators

    Science.gov (United States)

    2011-02-03

    ... UNION ADMINISTRATION Registration of Mortgage Loan Originators AGENCY: Office of the Comptroller of the..., Agency-regulated institutions) who act as a residential mortgage loan originator to register with the... registration system for mortgage loan originators. Specifically, the Act requires: (1) All States to provide...

  12. Discrete-Time LPV Current Control of an Induction Motor

    DEFF Research Database (Denmark)

    Bendtsen, Jan Dimon; Trangbæk, Klaus

    2003-01-01

    In this paper we apply a new method for gain-scheduled output feedback control of nonlinear systems to current control of an induction motor. The method relies on recently developed controller synthesis results for linear parameter-varying (LPV) systems, where the controller synthesis is formulated...... as a set of linear matrix inequalities with full-block multipliers. A standard nonlinear model of the motor is constructed and written on LPV form. We then show that, although originally developed in continuous time, the controller synthesis results can be applied to a discrete-time model as well without...... further complications. The synthesis method is applied to the model, yielding an LPV discrete-time controller. Finally, the efficiency of the control scheme is validated via simulations as well as on the actual induction motor, both in open-loop current control and when an outer speed control loop...

  13. Canny edge-based deformable image registration.

    Science.gov (United States)

    Kearney, Vasant; Huang, Yihui; Mao, Weihua; Yuan, Baohong; Tang, Liping

    2017-02-07

    This work focuses on developing a 2D Canny edge-based deformable image registration (Canny DIR) algorithm to register in vivo white light images taken at various time points. This method uses a sparse interpolation deformation algorithm to sparsely register regions of the image with strong edge information. A stability criterion is enforced which removes regions of edges that do not deform in a smooth uniform manner. Using a synthetic mouse surface ground truth model, the accuracy of the Canny DIR algorithm was evaluated under axial rotation in the presence of deformation. The accuracy was also tested using fluorescent dye injections, which were then used for gamma analysis to establish a second ground truth. The results indicate that the Canny DIR algorithm performs better than rigid registration, intensity corrected Demons, and distinctive features for all evaluation matrices and ground truth scenarios. In conclusion Canny DIR performs well in the presence of the unique lighting and shading variations associated with white-light-based image registration.

  14. 77 FR 43078 - Federal Acquisition Regulation; Information Collection; Central Contractor Registration

    Science.gov (United States)

    2012-07-23

    ...; Information Collection; Central Contractor Registration AGENCY: Department of Defense (DOD), General Services... requirement concerning the Central Contractor Registration database. Public comments are particularly invited... Information Collection 9000- 0159, Central Contractor Registration, by any of the following methods...

  15. Current Control of Grid Converters Connected with Series AC Capacitor

    DEFF Research Database (Denmark)

    Wang, Xiongfei; Blaabjerg, Frede; Loh, Poh Chiang

    2015-01-01

    The series ac capacitor has recently been used with the transformerless grid-connected converters in the distribution power grids. The capacitive characteristic of the resulting series LC filter restricts the use of conventional synchronous integral or stationary resonant current controllers. Thus...... this paper proposes a fourth-order resonant controller in the stationary frame, which guarantees a zero steady-state current tracking error for the grid converters with series LC filter. This method is then implemented in a three-phase experimental system for verification, where the current harmonics below...... the LC filter resonance frequency are effectively eliminated. Experimental results confirm the validity of the proposed current control scheme....

  16. Generalized space vector control for current source inverters and rectifiers

    Directory of Open Access Journals (Sweden)

    Roseline J. Anitha

    2016-06-01

    Full Text Available Current source inverters (CSI is one of the widely used converter topology in medium voltage drive applications due to its simplicity, motor friendly waveforms and reliable short circuit protection. The current source inverters are usually fed by controlled current source rectifiers (CSR with a large inductor to provide a constant supply current. A generalized control applicable for both CSI and CSR and their extension namely current source multilevel inverters (CSMLI are dealt in this paper. As space vector pulse width modulation (SVPWM features the advantages of flexible control, faster dynamic response, better DC utilization and easy digital implementation it is considered for this work. This paper generalizes SVPWM that could be applied for CSI, CSR and CSMLI. The intense computation involved in framing a generalized space vector control are discussed in detail. The algorithm includes determination of band, region, subregions and vectors. The algorithm is validated by simulation using MATLAB /SIMULINK for CSR 5, 7, 13 level CSMLI and for CSR fed CSI.

  17. Gaussian Process Interpolation for Uncertainty Estimation in Image Registration

    Science.gov (United States)

    Wachinger, Christian; Golland, Polina; Reuter, Martin; Wells, William

    2014-01-01

    Intensity-based image registration requires resampling images on a common grid to evaluate the similarity function. The uncertainty of interpolation varies across the image, depending on the location of resampled points relative to the base grid. We propose to perform Bayesian inference with Gaussian processes, where the covariance matrix of the Gaussian process posterior distribution estimates the uncertainty in interpolation. The Gaussian process replaces a single image with a distribution over images that we integrate into a generative model for registration. Marginalization over resampled images leads to a new similarity measure that includes the uncertainty of the interpolation. We demonstrate that our approach increases the registration accuracy and propose an efficient approximation scheme that enables seamless integration with existing registration methods. PMID:25333127

  18. Tissue Feature-Based and Segmented Deformable Image Registration for Improved Modeling of Shear Movement of Lungs

    International Nuclear Information System (INIS)

    Xie Yaoqin; Chao Ming; Xing Lei

    2009-01-01

    Purpose: To report a tissue feature-based image registration strategy with explicit inclusion of the differential motions of thoracic structures. Methods and Materials: The proposed technique started with auto-identification of a number of corresponding points with distinct tissue features. The tissue feature points were found by using the scale-invariant feature transform method. The control point pairs were then sorted into different 'colors' according to the organs in which they resided and used to model the involved organs individually. A thin-plate spline method was used to register a structure characterized by the control points with a given 'color.' The proposed technique was applied to study a digital phantom case and 3 lung and 3 liver cancer patients. Results: For the phantom case, a comparison with the conventional thin-plate spline method showed that the registration accuracy was markedly improved when the differential motions of the lung and chest wall were taken into account. On average, the registration error and standard deviation of the 15 points against the known ground truth were reduced from 3.0 to 0.5 mm and from 1.5 to 0.2 mm, respectively, when the new method was used. A similar level of improvement was achieved for the clinical cases. Conclusion: The results of our study have shown that the segmented deformable approach provides a natural and logical solution to model the discontinuous organ motions and greatly improves the accuracy and robustness of deformable registration.

  19. 78 FR 12316 - Federal Acquisition Regulation; Information Collection; Central Contractor Registration

    Science.gov (United States)

    2013-02-22

    ...; Information Collection; Central Contractor Registration AGENCIES: Department of Defense (DOD), General... collection requirement concerning the Central Contractor Registration database. A notice was published in the... Information Collection 9000- 0159, Central Contractor Registration, by any of the following methods...

  20. Improving alignment in Tract-based spatial statistics: evaluation and optimization of image registration.

    Science.gov (United States)

    de Groot, Marius; Vernooij, Meike W; Klein, Stefan; Ikram, M Arfan; Vos, Frans M; Smith, Stephen M; Niessen, Wiro J; Andersson, Jesper L R

    2013-08-01

    Anatomical alignment in neuroimaging studies is of such importance that considerable effort is put into improving the registration used to establish spatial correspondence. Tract-based spatial statistics (TBSS) is a popular method for comparing diffusion characteristics across subjects. TBSS establishes spatial correspondence using a combination of nonlinear registration and a "skeleton projection" that may break topological consistency of the transformed brain images. We therefore investigated feasibility of replacing the two-stage registration-projection procedure in TBSS with a single, regularized, high-dimensional registration. To optimize registration parameters and to evaluate registration performance in diffusion MRI, we designed an evaluation framework that uses native space probabilistic tractography for 23 white matter tracts, and quantifies tract similarity across subjects in standard space. We optimized parameters for two registration algorithms on two diffusion datasets of different quality. We investigated reproducibility of the evaluation framework, and of the optimized registration algorithms. Next, we compared registration performance of the regularized registration methods and TBSS. Finally, feasibility and effect of incorporating the improved registration in TBSS were evaluated in an example study. The evaluation framework was highly reproducible for both algorithms (R(2) 0.993; 0.931). The optimal registration parameters depended on the quality of the dataset in a graded and predictable manner. At optimal parameters, both algorithms outperformed the registration of TBSS, showing feasibility of adopting such approaches in TBSS. This was further confirmed in the example experiment. Copyright © 2013 Elsevier Inc. All rights reserved.

  1. Short-Term Impacts of Formalization Assistance and a Bank Information Session on Business Registration and Access to Finance in Malawi

    OpenAIRE

    Campos, Francisco; Goldstein, Markus; McKenzie, David

    2015-01-01

    Despite regulatory efforts designed to make it easier for firms to formalize, informality remains extremely high among firms in Sub-Saharan Africa. In most of the region, business registration in a national registry is separate from tax registration. This paper provides initial results from an experiment in Malawi that randomly allocated firms into a control group and three treatment groups: a) a ...

  2. 76 FR 77824 - Dicofol; Cancellation Order for Certain Pesticide Registrations

    Science.gov (United States)

    2011-12-14

    ..., sale, or use of existing stocks of the products identified in Tables 1 and 2 of Unit II in a manner..., 2011 Federal Register Notice of Receipt of Requests from the registrants listed in Table 3 of Unit II.... These registrations are listed in sequence by registration number in Table 1 and Table 2 of this unit...

  3. 75 FR 35805 - Pesticide Product Registrations; Conditional Approvals

    Science.gov (United States)

    2010-06-23

    ... submitted by April 1, 2009. 5. Insect Resistance Management: To support sweet corn uses, baseline... support these registrations, except for material specifically protected by section 10 of FIFRA, are also... following data/information must be submitted to the Agency to support the registration of MON 89034: 1...

  4. ER-1A-DEL-92 regulation. Procedure for evaluation and registration of medical equipment

    International Nuclear Information System (INIS)

    2015-01-01

    The objectives of this regulation is to provide additional guidance on the method of evaluation and registration of a medical team, so it is used by manufacturers, health institutions, testing centers and other institutions related to the topic. The provisions of this regulation apply to domestically produced medical equipment in relation to the necessary assessment for registration purposes of a medical team. However, the evaluation process may require evaluations and tests not explicitly included in this regulation, so that at each stage of the process the Center for State Control of Medical Equipment (Center) set the requirements for each computer or device class in particular.

  5. CO-REGISTRATION AIRBORNE LIDAR POINT CLOUD DATA AND SYNCHRONOUS DIGITAL IMAGE REGISTRATION BASED ON COMBINED ADJUSTMENT

    Directory of Open Access Journals (Sweden)

    Z. H. Yang

    2016-06-01

    Full Text Available Aim at the problem of co-registration airborne laser point cloud data with the synchronous digital image, this paper proposed a registration method based on combined adjustment. By integrating tie point, point cloud data with elevation constraint pseudo observations, using the principle of least-squares adjustment to solve the corrections of exterior orientation elements of each image, high-precision registration results can be obtained. In order to ensure the reliability of the tie point, and the effectiveness of pseudo observations, this paper proposed a point cloud data constrain SIFT matching and optimizing method, can ensure that the tie points are located on flat terrain area. Experiments with the airborne laser point cloud data and its synchronous digital image, there are about 43 pixels error in image space using the original POS data. If only considering the bore-sight of POS system, there are still 1.3 pixels error in image space. The proposed method regards the corrections of the exterior orientation elements of each image as unknowns and the errors are reduced to 0.15 pixels.

  6. Recent Advances in Registration, Integration and Fusion of Remotely Sensed Data: Redundant Representations and Frames

    Science.gov (United States)

    Czaja, Wojciech; Le Moigne-Stewart, Jacqueline

    2014-01-01

    In recent years, sophisticated mathematical techniques have been successfully applied to the field of remote sensing to produce significant advances in applications such as registration, integration and fusion of remotely sensed data. Registration, integration and fusion of multiple source imagery are the most important issues when dealing with Earth Science remote sensing data where information from multiple sensors, exhibiting various resolutions, must be integrated. Issues ranging from different sensor geometries, different spectral responses, differing illumination conditions, different seasons, and various amounts of noise need to be dealt with when designing an image registration, integration or fusion method. This tutorial will first define the problems and challenges associated with these applications and then will review some mathematical techniques that have been successfully utilized to solve them. In particular, we will cover topics on geometric multiscale representations, redundant representations and fusion frames, graph operators, diffusion wavelets, as well as spatial-spectral and operator-based data fusion. All the algorithms will be illustrated using remotely sensed data, with an emphasis on current and operational instruments.

  7. A unified grid current control for grid-interactive DG inverters in microgrids

    DEFF Research Database (Denmark)

    Wang, Xiongfei; Loh, Poh Chiang; Blaabjerg, Frede

    2015-01-01

    This paper proposes a unified grid current control for grid-interactive distributed generation inverters. In the approach, the grid-side current, instead of inverter-side current, is controlled as an inner loop, while the filter capacitor voltage is indirectly regulated through a virtual admittan...... locus analyses in the discrete z-domain are performed for elaborating the controller design. Simulations and experimental results demonstrate the performances of the proposed approach.......This paper proposes a unified grid current control for grid-interactive distributed generation inverters. In the approach, the grid-side current, instead of inverter-side current, is controlled as an inner loop, while the filter capacitor voltage is indirectly regulated through a virtual admittance...... in the outer loop. It, therefore, provides several superior features over traditional control schemes: 1) high-quality grid current in the grid-connected mode, 2) inherent derivative-less virtual output impedance control, and 3) the unified active damping for both grid-connected and islanded operations. Root...

  8. Registration of acute stroke

    DEFF Research Database (Denmark)

    Wildenschild, Cathrine; Mehnert, Frank; Thomsen, Reimar Wernich

    2014-01-01

    BACKGROUND: The validity of the registration of patients in stroke-specific registries has seldom been investigated, nor compared with administrative hospital discharge registries. The objective of this study was to examine the validity of the registration of patients in a stroke-specific registry...... (The Danish Stroke Registry [DSR]) and a hospital discharge registry (The Danish National Patient Registry [DNRP]). METHODS: Assuming that all patients with stroke were registered in either the DSR, DNRP or both, we first identified a sample of 75 patients registered with stroke in 2009; 25 patients...... in the DSR, 25 patients in the DNRP, and 25 patients registered in both data sources. Using the medical record as a gold standard, we then estimated the sensitivity and positive predictive value of a stroke diagnosis in the DSR and the DNRP. Secondly, we reviewed 160 medical records for all potential stroke...

  9. Microbial control of phytophagous invertebrate pests in South Africa: Current status and future prospects.

    Science.gov (United States)

    Hatting, Justin L; Moore, Sean D; Malan, Antoinette P

    2018-02-07

    Invertebrate pests pose a significant threat to food security on the African continent. In response, South Africa has become one of the largest importers of chemical pesticides in sub-Saharan Africa, with several hundred active ingredients registered. To address the over-reliance on such chemicals, the South African Department of Agriculture, Forestry and Fisheries (DAFF) has eliminated or restricted several pesticides since the late 1970s. The recent launch of the South African National Bio-Economy Strategy and establishment of the South African Bioproducts Organisation (SABO), together with new guidelines for registration of biopesticides in 2015, also support this endeavour. Concurrently, entomopathogen-related research and bioproduct development has increased over the past decade. Currently, 31 products (seven manufactured locally) are registered under the Fertilizers, Farm Feeds, Agricultural Remedies and Stock Remedies Act 36 of 1947. Commercially important microbes include Beauveria bassiana (Cordycipitaceae), Metarhizium anisopliae (Clavicipitaceae), Cydia pomonella granulovirus, Cryptophlebia leucotreta granulovirus, Helicoverpa armigera nucleopolyhedrovirus (Baculoviridae) and Bacillus thuringiensis subsp. kurstaki and B. thuringiensis subsp. aizawai (Bacillaceae). Both parasitic and entomopathogenic nematodes (EPNs) show potential for development as bioinsecticides with one commercial EPN product, based on Heterorhabditis bacteriophora (Heterorhabditidae), registered under the Act. Rapid scientific progression, supported by a favourable legislative environment, should facilitate further advances in microbial control of phytophagous invertebrate pests in South Africa. Copyright © 2018 Elsevier Inc. All rights reserved.

  10. Registration for public drug benefits across areas of differing ethnic composition in British Columbia, Canada

    Directory of Open Access Journals (Sweden)

    Wong Sabrina T

    2010-06-01

    Full Text Available Abstract Background In 2003, the government of British Columbia, Canada introduced a universal drug benefit plan to cover drug costs that are high relative to household income. Residents were required to register in order to be eligible for the income-based benefits. Given past research suggesting that registration processes may pose an access barrier to certain subpopulations, we aimed to determine whether registration rates varied across small geographic areas that differed in ethnic composition. Methods Using linked population-based administrative databases and census data, we conducted multivariate logistic regression analyses to determine whether the probability of registration for the public drug plan varied across areas of differing ethnic composition, controlling for household-level predisposing, enabling and needs factors. Results The adjusted odds of registration did not differ across regions characterized by high concentrations (greater than 30% of residents identifying as North American, British, French or other European. Households located in areas with concentrations of residents identifying as an Asian ethnicity had the highest odds of program registration: Chinese (OR = 1.21, CI: 1.19-1.23 and South Asian (OR = 1.19, CI: 1.16-1.22. Despite this positive finding, households residing in areas with relatively high concentrations of recent immigrants had slightly lower adjusted odds of registering for the program (OR = 0.97, CI: 0.95-0.98. Conclusions This study identified ethnic variation in registration for a new public drug benefit program in British Columbia. However, unlike previous studies, the variation observed did not indicate that areas with high concentrations of certain ethnicities experienced disadvantages. Potential explanations are discussed.

  11. Evaluation of registration methods on thoracic CT

    DEFF Research Database (Denmark)

    Murphy, K.; van Ginneken, B.; Reinhardt, J.

    2011-01-01

    method and the evaluation is independent, using the same criteria for all participants. All results are published on the EMPIRE10 website (http://empire10.isi.uu.nl). The challenge remains ongoing and open to new participants. Full results from 24 algorithms have been published at the time of writing......EMPIRE10 (Evaluation of Methods for Pulmonary Image REgistration 2010) is a public platform for fair and meaningful comparison of registration algorithms which are applied to a database of intra-patient thoracic CT image pairs. Evaluation of non-rigid registration techniques is a non trivial task....... This article details the organisation of the challenge, the data and evaluation methods and the outcome of the initial launch with 20 algorithms. The gain in knowledge and future work are discussed....

  12. Image Segmentation, Registration, Compression, and Matching

    Science.gov (United States)

    Yadegar, Jacob; Wei, Hai; Yadegar, Joseph; Ray, Nilanjan; Zabuawala, Sakina

    2011-01-01

    A novel computational framework was developed of a 2D affine invariant matching exploiting a parameter space. Named as affine invariant parameter space (AIPS), the technique can be applied to many image-processing and computer-vision problems, including image registration, template matching, and object tracking from image sequence. The AIPS is formed by the parameters in an affine combination of a set of feature points in the image plane. In cases where the entire image can be assumed to have undergone a single affine transformation, the new AIPS match metric and matching framework becomes very effective (compared with the state-of-the-art methods at the time of this reporting). No knowledge about scaling or any other transformation parameters need to be known a priori to apply the AIPS framework. An automated suite of software tools has been created to provide accurate image segmentation (for data cleaning) and high-quality 2D image and 3D surface registration (for fusing multi-resolution terrain, image, and map data). These tools are capable of supporting existing GIS toolkits already in the marketplace, and will also be usable in a stand-alone fashion. The toolkit applies novel algorithmic approaches for image segmentation, feature extraction, and registration of 2D imagery and 3D surface data, which supports first-pass, batched, fully automatic feature extraction (for segmentation), and registration. A hierarchical and adaptive approach is taken for achieving automatic feature extraction, segmentation, and registration. Surface registration is the process of aligning two (or more) data sets to a common coordinate system, during which the transformation between their different coordinate systems is determined. Also developed here are a novel, volumetric surface modeling and compression technique that provide both quality-guaranteed mesh surface approximations and compaction of the model sizes by efficiently coding the geometry and connectivity

  13. Control of the current density profile with lower hybrid current drive on PBX-M

    International Nuclear Information System (INIS)

    Bell, R.E.; Bernabei, S.; Chu, T.K.; Gettelfinger, G.; Greenough, N.; Hatcher, R.; Ignat, D.; Jardin, S.; Kaita, R.; Kaye, S.; Kozub, T.; Kugel, H.; LeBlanc, B.; Okabayashi, M.; Paul, S.; Sauthoff, N.; Sesnic, S.; Sun, Y.; Takahashi, H.; Tighe, W.; Valeo, E.; von Goeler, S.; Jones, S.; Kesner, J.; Luckhardt, S.; Paoletti, F.; Levinton, F.; Timini, F.

    1993-07-01

    Lower hybrid current drive (LHCD) is being explored as a means to control the current density profile on PBX-M with the goal of raising the central safety factor q(O) to values of 1.5-2 to facilitate access to a full-volume second stable regime. Initial experiments have been conducted with up to 400 kW of 4.6 GHz LH power in circular and indented plasmas with modest parameters. A tangential-viewing two-dimensional hard x-ray imaging diagnostic has been used to observe the bremsstrahlung emission from the suprathermal electrons generated during LHCD. Hollow hard x-ray images have indicated off-axis localization of the driven current. A serious obstacle to the control of the current density profile with LHCD is the concomitant generation of MHD activity, which can seriously degrade the confinement of suprathermal electrons. By combining neutral beam injection with LHCD, an MHD-free condition has been obtained where q(O) is raised above 1

  14. Comparison of manual and automatic MR-CT registration for radiotherapy of prostate cancer.

    Science.gov (United States)

    Korsager, Anne Sofie; Carl, Jesper; Riis Østergaard, Lasse

    2016-05-08

    In image-guided radiotherapy (IGRT) of prostate cancer, delineation of the clini-cal target volume (CTV) often relies on magnetic resonance (MR) because of its good soft-tissue visualization. Registration of MR and computed tomography (CT) is required in order to add this accurate delineation to the dose planning CT. An automatic approach for local MR-CT registration of the prostate has previously been developed using a voxel property-based registration as an alternative to a manual landmark-based registration. The aim of this study is to compare the two registration approaches and to investigate the clinical potential for replacing the manual registration with the automatic registration. Registrations and analysis were performed for 30 prostate cancer patients treated with IGRT using a Ni-Ti prostate stent as a fiducial marker. The comparison included computing translational and rotational differences between the approaches, visual inspection, and computing the overlap of the CTV. The computed mean translational difference was 1.65, 1.60, and 1.80mm and the computed mean rotational difference was 1.51°, 3.93°, and 2.09° in the superior/inferior, anterior/posterior, and medial/lateral direction, respectively. The sensitivity of overlap was 87%. The results demonstrate that the automatic registration approach performs registrations comparable to the manual registration.

  15. Do emergency medicine journals promote trial registration and adherence to reporting guidelines? A survey of "Instructions for Authors".

    Science.gov (United States)

    Sims, Matthew T; Henning, Nolan M; Wayant, C Cole; Vassar, Matt

    2016-11-24

    The aim of this study was to evaluate the current state of two publication practices, reporting guidelines requirements and clinical trial registration requirements, by analyzing the "Instructions for Authors" of emergency medicine journals. We performed a web-based data abstraction from the "Instructions for Authors" of the 27 Emergency Medicine journals catalogued in the Expanded Science Citation Index of the 2014 Journal Citation Reports and Google Scholar Metrics h5-index to identify whether each journal required, recommended, or made no mention of the following reporting guidelines: EQUATOR Network, ICMJE, ARRIVE, CARE, CONSORT, STARD, TRIPOD, CHEERS, MOOSE, STROBE, COREQ, SRQR, SQUIRE, PRISMA-P, SPIRIT, PRISMA, and QUOROM. We also extracted whether journals required or recommended trial registration. Authors were blinded to one another's ratings until completion of the data validation. Cross-tabulations and descriptive statistics were calculated using IBM SPSS 22. Of the 27 emergency medicine journals, 11 (11/27, 40.7%) did not mention a single guideline within their "Instructions for Authors," while the remaining 16 (16/27, 59.3%) mentioned one or more guidelines. The QUOROM statement and SRQR were not mentioned by any journals whereas the ICMJE guidelines (18/27, 66.7%) and CONSORT statement (15/27, 55.6%) were mentioned most often. Of the 27 emergency medicine journals, 15 (15/27, 55.6%) did not mention trial or review registration, while the remaining 12 (12/27, 44.4%) at least mentioned one of the two. Trial registration through ClinicalTrials.gov was mentioned by seven (7/27, 25.9%) journals while the WHO registry was mentioned by four (4/27, 14.8%). Twelve (12/27, 44.4%) journals mentioned trial registration through any registry platform. The aim of this study was to evaluate the current state of two publication practices, reporting guidelines requirements and clinical trial registration requirements, by analyzing the "Instructions for Authors" of

  16. 3D Rigid Registration by Cylindrical Phase Correlation Method

    Czech Academy of Sciences Publication Activity Database

    Bican, Jakub; Flusser, Jan

    2009-01-01

    Roč. 30, č. 10 (2009), s. 914-921 ISSN 0167-8655 R&D Projects: GA MŠk 1M0572; GA ČR GA102/08/1593 Grant - others:GAUK(CZ) 48908 Institutional research plan: CEZ:AV0Z10750506 Keywords : 3D registration * correlation methods * Image registration Subject RIV: BD - Theory of Information Impact factor: 1.303, year: 2009 http://library.utia.cas.cz/separaty/2009/ZOI/bican-3d digit registration by cylindrical phase correlation method.pdf

  17. Multimodal image registration based on binary gradient angle descriptor.

    Science.gov (United States)

    Jiang, Dongsheng; Shi, Yonghong; Yao, Demin; Fan, Yifeng; Wang, Manning; Song, Zhijian

    2017-12-01

    Multimodal image registration plays an important role in image-guided interventions/therapy and atlas building, and it is still a challenging task due to the complex intensity variations in different modalities. The paper addresses the problem and proposes a simple, compact, fast and generally applicable modality-independent binary gradient angle descriptor (BGA) based on the rationale of gradient orientation alignment. The BGA can be easily calculated at each voxel by coding the quadrant in which a local gradient vector falls, and it has an extremely low computational complexity, requiring only three convolutions, two multiplication operations and two comparison operations. Meanwhile, the binarized encoding of the gradient orientation makes the BGA more resistant to image degradations compared with conventional gradient orientation methods. The BGA can extract similar feature descriptors for different modalities and enable the use of simple similarity measures, which makes it applicable within a wide range of optimization frameworks. The results for pairwise multimodal and monomodal registrations between various images (T1, T2, PD, T1c, Flair) consistently show that the BGA significantly outperforms localized mutual information. The experimental results also confirm that the BGA can be a reliable alternative to the sum of absolute difference in monomodal image registration. The BGA can also achieve an accuracy of [Formula: see text], similar to that of the SSC, for the deformable registration of inhale and exhale CT scans. Specifically, for the highly challenging deformable registration of preoperative MRI and 3D intraoperative ultrasound images, the BGA achieves a similar registration accuracy of [Formula: see text] compared with state-of-the-art approaches, with a computation time of 18.3 s per case. The BGA improves the registration performance in terms of both accuracy and time efficiency. With further acceleration, the framework has the potential for

  18. Ultrasound to video registration using a bi-plane transrectal probe with photoacoustic markers

    Science.gov (United States)

    Cheng, Alexis; Kang, Hyun Jae; Zhang, Haichong K.; Taylor, Russell H.; Boctor, Emad M.

    2016-03-01

    Modern surgical scenarios typically provide surgeons with additional information through fusion of video and other imaging modalities. To provide this information, the tools and devices used in surgery must be registered together with interventional guidance equipment and surgical navigation systems. In this work, we focus explicitly on registering ultrasound with a stereo camera system using photoacoustic markers. Previous work has shown that photoacoustic markers can be used in this registration task to achieve target registration errors lower than the current available systems. Photoacoustic markers are defined as a set of non-collinear laser spots projected onto some surface. They can be simultaneously visualized by a stereo camera system and an ultrasound transducer because of the photoacoustic effect. In more recent work, the three-dimensional ultrasound volume was replaced by images from a single ultrasound image pose from a convex array transducer. The feasibility of this approach was demonstrated, but the accuracy was lacking due to the physical limitations of the convex array transducer. In this work, we propose the use of a bi-plane transrectal ultrasound transducer. The main advantage of using this type of transducer is that the ultrasound elements are no longer restricted to a single plane. While this development would be limited to prostate applications, liver and kidney applications are also feasible if a suitable transducer is built. This work is demonstrated in two experiments, one without photoacoustic sources and one with. The resulting target registration error for these experiments were 1.07mm±0.35mm and 1.27mm+/-0.47mm respectively, both of which are better than current available navigation systems.

  19. Disturbance estimator based predictive current control of grid-connected inverters

    OpenAIRE

    Al-Khafaji, Ahmed Samawi Ghthwan

    2013-01-01

    ABSTRACT: The work presented in my thesis considers one of the modern discrete-time control approaches based on digital signal processing methods, that have been developed to improve the performance control of grid-connected three-phase inverters. Disturbance estimator based predictive current control of grid-connected inverters is proposed. For inverter modeling with respect to the design of current controllers, we choose the d-q synchronous reference frame to make it easier to understand an...

  20. Robust inverse-consistent affine CT-MR registration in MRI-assisted and MRI-alone prostate radiation therapy.

    Science.gov (United States)

    Rivest-Hénault, David; Dowson, Nicholas; Greer, Peter B; Fripp, Jurgen; Dowling, Jason A

    2015-07-01

    CT-MR registration is a critical component of many radiation oncology protocols. In prostate external beam radiation therapy, it allows the propagation of MR-derived contours to reference CT images at the planning stage, and it enables dose mapping during dosimetry studies. The use of carefully registered CT-MR atlases allows the estimation of patient specific electron density maps from MRI scans, enabling MRI-alone radiation therapy planning and treatment adaptation. In all cases, the precision and accuracy achieved by registration influences the quality of the entire process. Most current registration algorithms do not robustly generalize and lack inverse-consistency, increasing the risk of human error and acting as a source of bias in studies where information is propagated in a particular direction, e.g. CT to MR or vice versa. In MRI-based treatment planning where both CT and MR scans serve as spatial references, inverse-consistency is critical, if under-acknowledged. A robust, inverse-consistent, rigid/affine registration algorithm that is well suited to CT-MR alignment in prostate radiation therapy is presented. The presented method is based on a robust block-matching optimization process that utilises a half-way space definition to maintain inverse-consistency. Inverse-consistency substantially reduces the influence of the order of input images, simplifying analysis, and increasing robustness. An open source implementation is available online at http://aehrc.github.io/Mirorr/. Experimental results on a challenging 35 CT-MR pelvis dataset demonstrate that the proposed method is more accurate than other popular registration packages and is at least as accurate as the state of the art, while being more robust and having an order of magnitude higher inverse-consistency than competing approaches. The presented results demonstrate that the proposed registration algorithm is readily applicable to prostate radiation therapy planning. Copyright © 2015. Published by

  1. Current developments in bovine mastitis treatment and control.

    Science.gov (United States)

    Wager, L A; Linquist, W E; Hayes, G L; Britten, A M; Whitehead, R G; Webster, D E; Barnes, F D

    1978-01-01

    Mastitis in its complexity has managed to forestall all efforts of eradication in spite of years of research, antibiotics and practical control measures. This minisymposium will touch on seven topics current to treatment and control of this economically important disease.

  2. Evaluation of registration methods on thoracic CT : the EMPIRE10 challenge

    NARCIS (Netherlands)

    Murphy, K.; Ginneken, van B.; Reinhardt, J.M.; Kabus, S.; Ding, K.; Deng, Xiang; Cao, K.; Du, K.; Christensen, G.E.; Garcia, V.; Vercauteren, T.; Ayache, N.; Commowick, O.; Malandain, G.; Glocker, B.; Paragios, N.; Navab, N.; Gorbunova, V.; Sporring, J.; Bruijne, de M.; Han, Xiao; Heinrich, M.P.; Schnabel, J.A.; Jenkinson, M.; Lorenz, C.; Modat, M.; McClelland, J.R.; Ourselin, S.; Muenzing, S.E.A.; Viergever, M.A.; Nigris, De D.; Collins, D.L.; Arbel, T.; Peroni, M.; Li, R.; Sharp, G.; Schmidt-Richberg, A.; Ehrhardt, J.; Werner, R.; Smeets, D.; Loeckx, D.; Song, G.; Tustison, N.; Avants, B.; Gee, J.C.; Staring, M.; Klein, S.; Stoel, B.C.; Urschler, M.; Werlberger, M.; Vandemeulebroucke, J.; Rit, S.; Sarrut, D.; Pluim, J.P.W.

    2011-01-01

    EMPIRE10 (Evaluation of Methods for Pulmonary Image REgistration 2010) is a public platform for fair and meaningful comparison of registration algorithms which are applied to a database of intrapatient thoracic CT image pairs. Evaluation of nonrigid registration techniques is a nontrivial task. This

  3. Markerless laser registration in image-guided oral and maxillofacial surgery.

    Science.gov (United States)

    Marmulla, Rüdiger; Lüth, Tim; Mühling, Joachim; Hassfeld, Stefan

    2004-07-01

    The use of registration markers in computer-assisted surgery is combined with high logistic costs and efforts. Markerless patient registration using laser scan surface registration techniques is a new challenging method. The present study was performed to evaluate the clinical accuracy in finding defined target points within the surgical site after markerless patient registration in image-guided oral and maxillofacial surgery. Twenty consecutive patients with different cranial diseases were scheduled for computer-assisted surgery. Data set alignment between the surgical site and the computed tomography (CT) data set was performed by markerless laser scan surface registration of the patient's face. Intraoral rigidly attached registration markers were used as target points, which had to be detected by an infrared pointer. The Surgical Segment Navigator SSN++ has been used for all procedures. SSN++ is an investigative product based on the SSN system that had previously been developed by the presenting authors with the support of Carl Zeiss (Oberkochen, Germany). SSN++ is connected to a Polaris infrared camera (Northern Digital, Waterloo, Ontario, Canada) and to a Minolta VI 900 3D digitizer (Tokyo, Japan) for high-resolution laser scanning. Minimal differences in shape between the laser scan surface and the surface generated from the CT data set could be detected. Nevertheless, high-resolution laser scan of the skin surface allows for a precise patient registration (mean deviation 1.1 mm, maximum deviation 1.8 mm). Radiation load, logistic costs, and efforts arising from the planning of computer-assisted surgery of the head can be reduced because native (markerless) CT data sets can be used for laser scan-based surface registration.

  4. On developing B-spline registration algorithms for multi-core processors

    International Nuclear Information System (INIS)

    Shackleford, J A; Kandasamy, N; Sharp, G C

    2010-01-01

    Spline-based deformable registration methods are quite popular within the medical-imaging community due to their flexibility and robustness. However, they require a large amount of computing time to obtain adequate results. This paper makes two contributions towards accelerating B-spline-based registration. First, we propose a grid-alignment scheme and associated data structures that greatly reduce the complexity of the registration algorithm. Based on this grid-alignment scheme, we then develop highly data parallel designs for B-spline registration within the stream-processing model, suitable for implementation on multi-core processors such as graphics processing units (GPUs). Particular attention is focused on an optimal method for performing analytic gradient computations in a data parallel fashion. CPU and GPU versions are validated for execution time and registration quality. Performance results on large images show that our GPU algorithm achieves a speedup of 15 times over the single-threaded CPU implementation whereas our multi-core CPU algorithm achieves a speedup of 8 times over the single-threaded implementation. The CPU and GPU versions achieve near-identical registration quality in terms of RMS differences between the generated vector fields.

  5. On removing interpolation and resampling artifacts in rigid image registration.

    Science.gov (United States)

    Aganj, Iman; Yeo, Boon Thye Thomas; Sabuncu, Mert R; Fischl, Bruce

    2013-02-01

    We show that image registration using conventional interpolation and summation approximations of continuous integrals can generally fail because of resampling artifacts. These artifacts negatively affect the accuracy of registration by producing local optima, altering the gradient, shifting the global optimum, and making rigid registration asymmetric. In this paper, after an extensive literature review, we demonstrate the causes of the artifacts by comparing inclusion and avoidance of resampling analytically. We show the sum-of-squared-differences cost function formulated as an integral to be more accurate compared with its traditional sum form in a simple case of image registration. We then discuss aliasing that occurs in rotation, which is due to the fact that an image represented in the Cartesian grid is sampled with different rates in different directions, and propose the use of oscillatory isotropic interpolation kernels, which allow better recovery of true global optima by overcoming this type of aliasing. Through our experiments on brain, fingerprint, and white noise images, we illustrate the superior performance of the integral registration cost function in both the Cartesian and spherical coordinates, and also validate the introduced radial interpolation kernel by demonstrating the improvement in registration.

  6. Robust non-rigid point set registration using student's-t mixture model.

    Directory of Open Access Journals (Sweden)

    Zhiyong Zhou

    Full Text Available The Student's-t mixture model, which is heavily tailed and more robust than the Gaussian mixture model, has recently received great attention on image processing. In this paper, we propose a robust non-rigid point set registration algorithm using the Student's-t mixture model. Specifically, first, we consider the alignment of two point sets as a probability density estimation problem and treat one point set as Student's-t mixture model centroids. Then, we fit the Student's-t mixture model centroids to the other point set which is treated as data. Finally, we get the closed-form solutions of registration parameters, leading to a computationally efficient registration algorithm. The proposed algorithm is especially effective for addressing the non-rigid point set registration problem when significant amounts of noise and outliers are present. Moreover, less registration parameters have to be set manually for our algorithm compared to the popular coherent points drift (CPD algorithm. We have compared our algorithm with other state-of-the-art registration algorithms on both 2D and 3D data with noise and outliers, where our non-rigid registration algorithm showed accurate results and outperformed the other algorithms.

  7. Deep Adaptive Log-Demons: Diffeomorphic Image Registration with Very Large Deformations

    Directory of Open Access Journals (Sweden)

    Liya Zhao

    2015-01-01

    Full Text Available This paper proposes a new framework for capturing large and complex deformation in image registration. Traditionally, this challenging problem relies firstly on a preregistration, usually an affine matrix containing rotation, scale, and translation and afterwards on a nonrigid transformation. According to preregistration, the directly calculated affine matrix, which is obtained by limited pixel information, may misregistrate when large biases exist, thus misleading following registration subversively. To address this problem, for two-dimensional (2D images, the two-layer deep adaptive registration framework proposed in this paper firstly accurately classifies the rotation parameter through multilayer convolutional neural networks (CNNs and then identifies scale and translation parameters separately. For three-dimensional (3D images, affine matrix is located through feature correspondences by a triplanar 2D CNNs. Then deformation removal is done iteratively through preregistration and demons registration. By comparison with the state-of-the-art registration framework, our method gains more accurate registration results on both synthetic and real datasets. Besides, principal component analysis (PCA is combined with correlation like Pearson and Spearman to form new similarity standards in 2D and 3D registration. Experiment results also show faster convergence speed.

  8. Image registration in gastric emptying studies

    International Nuclear Information System (INIS)

    Shuter, B.; Cooper, R.G.

    1998-01-01

    Full text: We have previously shown that image registration, based upon a two-dimensional cross-correlation (CC) of logarithmic Laplacian images (LLI), corrected motion in biliary studies in up to 90% of cases with minimal artifact. We have now applied the same technique to gastric emptying studies (GES). GES were acquired on an LFOV gamma camera over a two-hour period as 20-26 pairs of anterior-posterior frames (30 second duration and 64 x 64 matrix) for both solid and liquid components. All images were manually registered so that the solid contents of the stomach lay within an operator-drawn ROI. The anterior images of the solid component for 30 randomly selected patients were subjected to further image registration using CC of LLI, CC of raw images (Rl) (a common approach to image registration) and CC of Laplacian images (Ll). All images were aligned to the third image of the study, on which an ROI was drawn to outline the stomach. The number of images in which stomach counts appeared outside this ROI were tallied, in the original and all re-registered studies. Maximum displacements in X/Y position between images of studies registered by the LLI and Rl methods were also computed to directly compare positional accuracy. Stomachs partially exceeded the limits of the ROI in 27, 9, 53 and 54 frames (total of 710) in the original, LLI, Rl and Ll studies respectively. There were 4, 1, 6 and 7 studies with misregistered stomachs on more than 2 frames. Frames in seven Rl studies differed from the LLI studies in ) X/Y position by 3 pixels or more. Cross-correlation using LLI was the only method which improved upon the original manual registration. The Rl and Ll methods increased the number of misregistered frames. We conclude that in gastric emptying studies, as in biliary studies, object tracking by CC of LLI is the method of choice for image registration

  9. Balancing dose and image registration accuracy for cone beam tomosynthesis (CBTS) for breast patient setup

    International Nuclear Information System (INIS)

    Winey, B. A.; Zygmanski, P.; Cormack, R. A.; Lyatskaya, Y.

    2010-01-01

    Purpose: To balance dose reduction and image registration accuracy in breast setup imaging. In particular, the authors demonstrate the relationship between scan angle and dose delivery for cone beam tomosynthesis (CBTS) when employed for setup verification of breast cancer patients with surgical clips. Methods: The dose measurements were performed in a female torso phantom for varying scan angles of CBTS. Setup accuracy was measured using three registration methods: Clip centroid localization accuracy and the accuracy of two semiautomatic registration algorithms. The dose to the organs outside of the ipsilateral breast and registration accuracy information were compared to determine the optimal scan angle for CBTS for breast patient setup verification. Isocenter positions at the center of the patient and at the breast-chest wall interface were considered. Results: Image registration accuracy was within 1 mm for the CBTS scan angles θ above 20 deg. for some scenarios and as large as 80 deg. for the worst case, depending on the imaged breast and registration algorithm. Registration accuracy was highest based on clip centroid localization. For left and right breast imaging with the isocenter at the chest wall, the dose to the contralateral side of the patient was very low (<0.5 cGy) for all scan angles considered. For central isocenter location, the optimal scan angles were 30 deg. - 50 deg. for the left breast imaging and 40 deg. - 50 deg. for the right breast imaging, with the difference due to the geometric asymmetry of the current clinical imaging system. Conclusions: The optimal scan angles for CBTS imaging were found to be between 10 deg. and 50 deg., depending on the isocenter location and ipsilateral breast. Use of the isocenter at the breast-chest wall locations always resulted in greater accuracy of image registration (<1 mm) at smaller angles (10 deg. - 20 deg.) and at lower doses (<0.1 cGy) to the contralateral organs. For chest wall isocenters, doses

  10. Harmonic current control for LCL-filtered VSCs connected to ultra-weak grids

    DEFF Research Database (Denmark)

    Wang, Xiongfei; Yang, Dongsheng; Blaabjerg, Frede

    2017-01-01

    This paper addresses the harmonic current control for LCL-filtered Voltage-Source Converters (VSCs) connected to ultra-weak (high-impedance) grids. It is shown that the harmonic current controllers tend to be unstable as the Short-Circuit Ratio (SCR) of the system reduces. An active stabilizing...... control scheme is thus proposed by feeding back the filter capacitor voltage and the converter-side current. The method not only stabilizes the harmonic current control with a wide range of SCR values, but also mitigates harmonic distortions in the grid-side current of the VSC. The stabilizing mechanism...

  11. Robust image registration for multiple exposure high dynamic range image synthesis

    Science.gov (United States)

    Yao, Susu

    2011-03-01

    Image registration is an important preprocessing technique in high dynamic range (HDR) image synthesis. This paper proposed a robust image registration method for aligning a group of low dynamic range images (LDR) that are captured with different exposure times. Illumination change and photometric distortion between two images would result in inaccurate registration. We propose to transform intensity image data into phase congruency to eliminate the effect of the changes in image brightness and use phase cross correlation in the Fourier transform domain to perform image registration. Considering the presence of non-overlapped regions due to photometric distortion, evolutionary programming is applied to search for the accurate translation parameters so that the accuracy of registration is able to be achieved at a hundredth of a pixel level. The proposed algorithm works well for under and over-exposed image registration. It has been applied to align LDR images for synthesizing high quality HDR images..

  12. Multimodality Registration without a Dedicated Multimodality Scanner

    Directory of Open Access Journals (Sweden)

    Bradley J. Beattie

    2007-03-01

    Full Text Available Multimodality scanners that allow the acquisition of both functional and structural image sets on a single system have recently become available for animal research use. Although the resultant registered functional/structural image sets can greatly enhance the interpretability of the functional data, the cost of multimodality systems can be prohibitive, and they are often limited to two modalities, which generally do not include magnetic resonance imaging. Using a thin plastic wrap to immobilize and fix a mouse or other small animal atop a removable bed, we are able to calculate registrations between all combinations of four different small animal imaging scanners (positron emission tomography, single-photon emission computed tomography, magnetic resonance, and computed tomography [CT] at our disposal, effectively equivalent to a quadruple-modality scanner. A comparison of serially acquired CT images, with intervening acquisitions on other scanners, demonstrates the ability of the proposed procedures to maintain the rigidity of an anesthetized mouse during transport between scanners. Movement of the bony structures of the mouse was estimated to be 0.62 mm. Soft tissue movement was predominantly the result of the filling (or emptying of the urinary bladder and thus largely constrained to this region. Phantom studies estimate the registration errors for all registration types to be less than 0.5 mm. Functional images using tracers targeted to known structures verify the accuracy of the functional to structural registrations. The procedures are easy to perform and produce robust and accurate results that rival those of dedicated multimodality scanners, but with more flexible registration combinations and while avoiding the expense and redundancy of multimodality systems.

  13. A Comparative Study of Voltage, Peak Current and Dual Current Mode Control Methods for Noninverting Buck-Boost Converter

    Directory of Open Access Journals (Sweden)

    M. Č. Bošković

    2016-06-01

    Full Text Available This paper presents a comparison of voltage mode control (VMC and two current mode control (CMC methods of noninverting buck-boost converter. The converter control-to-output transfer function, line-to-output transfer function and the output impedance are obtained for all methods by averaging converter equations over one switching period and applying small-signal linearization. The obtained results are required for the design procedure of feedback compensator to keep a system stable and robust. A comparative study of VMC, peak current mode control (PCMC and dual-current mode control (DCMC is performed. Performance evaluation of the closed-loop system with obtained compensator between these methods is performed via numerical simulations.

  14. Comparison of manual and automatic MR‐CT registration for radiotherapy of prostate cancer

    Science.gov (United States)

    Carl, Jesper; Østergaard, Lasse Riis

    2016-01-01

    In image‐guided radiotherapy (IGRT) of prostate cancer, delineation of the clinical target volume (CTV) often relies on magnetic resonance (MR) because of its good soft‐tissue visualization. Registration of MR and computed tomography (CT) is required in order to add this accurate delineation to the dose planning CT. An automatic approach for local MR‐CT registration of the prostate has previously been developed using a voxel property‐based registration as an alternative to a manual landmark‐based registration. The aim of this study is to compare the two registration approaches and to investigate the clinical potential for replacing the manual registration with the automatic registration. Registrations and analysis were performed for 30 prostate cancer patients treated with IGRT using a Ni‐Ti prostate stent as a fiducial marker. The comparison included computing translational and rotational differences between the approaches, visual inspection, and computing the overlap of the CTV. The computed mean translational difference was 1.65, 1.60, and 1.80 mm and the computed mean rotational difference was 1.51°, 3.93°, and 2.09° in the superior/inferior, anterior/posterior, and medial/lateral direction, respectively. The sensitivity of overlap was 87%. The results demonstrate that the automatic registration approach performs registrations comparable to the manual registration. PACS number(s): 87.57.nj, 87.61.‐c, 87.57.Q‐, 87.56.J‐ PMID:27167285

  15. Feedback control of current drive by using hybrid wave in tokamaks

    International Nuclear Information System (INIS)

    Wijnands, T.J.; CEA Centre d'Etudes de Cadarache, 13 - Saint-Paul-lez-Durance

    1997-03-01

    This work is focussed on an important and recent development in present day Controlled Nuclear Fusion Research and Tokamaks. The aim is to optimise the energy confinement for a certain magnetic configuration by adapting the radial distribution of the current. Of particular interest are feedback control scenarios with stationary modifications of the current profile using current, driven by Lower Hybrid waves. A new feedback control system has been developed for Tore Supra and has made a large number of new operation scenarios possible. In one of the experiments described here, there is no energy exchange between the poloidal field system and the plasma, the current is controlled by the power of the Lower Hybrid waves while the launched wave spectrum is used to optimise the current profile shape and the energy confinement. (author)

  16. PCANet-Based Structural Representation for Nonrigid Multimodal Medical Image Registration

    Directory of Open Access Journals (Sweden)

    Xingxing Zhu

    2018-05-01

    Full Text Available Nonrigid multimodal image registration remains a challenging task in medical image processing and analysis. The structural representation (SR-based registration methods have attracted much attention recently. However, the existing SR methods cannot provide satisfactory registration accuracy due to the utilization of hand-designed features for structural representation. To address this problem, the structural representation method based on the improved version of the simple deep learning network named PCANet is proposed for medical image registration. In the proposed method, PCANet is firstly trained on numerous medical images to learn convolution kernels for this network. Then, a pair of input medical images to be registered is processed by the learned PCANet. The features extracted by various layers in the PCANet are fused to produce multilevel features. The structural representation images are constructed for two input images based on nonlinear transformation of these multilevel features. The Euclidean distance between structural representation images is calculated and used as the similarity metrics. The objective function defined by the similarity metrics is optimized by L-BFGS method to obtain parameters of the free-form deformation (FFD model. Extensive experiments on simulated and real multimodal image datasets show that compared with the state-of-the-art registration methods, such as modality-independent neighborhood descriptor (MIND, normalized mutual information (NMI, Weber local descriptor (WLD, and the sum of squared differences on entropy images (ESSD, the proposed method provides better registration performance in terms of target registration error (TRE and subjective human vision.

  17. Coarse Point Cloud Registration by Egi Matching of Voxel Clusters

    Science.gov (United States)

    Wang, Jinhu; Lindenbergh, Roderik; Shen, Yueqian; Menenti, Massimo

    2016-06-01

    Laser scanning samples the surface geometry of objects efficiently and records versatile information as point clouds. However, often more scans are required to fully cover a scene. Therefore, a registration step is required that transforms the different scans into a common coordinate system. The registration of point clouds is usually conducted in two steps, i.e. coarse registration followed by fine registration. In this study an automatic marker-free coarse registration method for pair-wise scans is presented. First the two input point clouds are re-sampled as voxels and dimensionality features of the voxels are determined by principal component analysis (PCA). Then voxel cells with the same dimensionality are clustered. Next, the Extended Gaussian Image (EGI) descriptor of those voxel clusters are constructed using significant eigenvectors of each voxel in the cluster. Correspondences between clusters in source and target data are obtained according to the similarity between their EGI descriptors. The random sampling consensus (RANSAC) algorithm is employed to remove outlying correspondences until a coarse alignment is obtained. If necessary, a fine registration is performed in a final step. This new method is illustrated on scan data sampling two indoor scenarios. The results of the tests are evaluated by computing the point to point distance between the two input point clouds. The presented two tests resulted in mean distances of 7.6 mm and 9.5 mm respectively, which are adequate for fine registration.

  18. The Iraqi civil registration system and the test of political upheaval

    Directory of Open Access Journals (Sweden)

    Sulaiman Bah

    2014-04-01

    Full Text Available An in-depth situation analysis was carried out on the Iraqi civil registration system in 2011, years after the end of the military operation of 2003. The study was done using a combination of methods, including interviews with key role players in the Iraqi civil registration system, observation, study of documents, triangulation, and gap analysis. The study found the civil registration system in Iraq to be largely intact and functional, in spite of the wars experienced in Iraq over the past three decades. Given that civil registration systems generally get destroyed through wars, the paper discusses the reasons for the resilience in the Iraqi civil registration system and draws lessons from them.

  19. An atlas-based multimodal registration method for 2D images with discrepancy structures.

    Science.gov (United States)

    Lv, Wenchao; Chen, Houjin; Peng, Yahui; Li, Yanfeng; Li, Jupeng

    2018-06-04

    An atlas-based multimodal registration method for 2-dimension images with discrepancy structures was proposed in this paper. Atlas was utilized for complementing the discrepancy structure information in multimodal medical images. The scheme includes three steps: floating image to atlas registration, atlas to reference image registration, and field-based deformation. To evaluate the performance, a frame model, a brain model, and clinical images were employed in registration experiments. We measured the registration performance by the squared sum of intensity differences. Results indicate that this method is robust and performs better than the direct registration for multimodal images with discrepancy structures. We conclude that the proposed method is suitable for multimodal images with discrepancy structures. Graphical Abstract An Atlas-based multimodal registration method schematic diagram.

  20. A current controlled variable delay superconducting transmission line

    International Nuclear Information System (INIS)

    Anlage, S.M.; Snortland, H.J.; Beasley, M.R.

    1989-01-01

    The authors present a device concept for a current-controlled variable delay for superconducting transmission line. The device makes use of the change in kinetic inductance of a superconducting transmission line under the application of a DC bias current. The relevant materials parameters and several promising superconducting materials have been identified

  1. Scan-based volume animation driven by locally adaptive articulated registrations.

    Science.gov (United States)

    Rhee, Taehyun; Lewis, J P; Neumann, Ulrich; Nayak, Krishna S

    2011-03-01

    This paper describes a complete system to create anatomically accurate example-based volume deformation and animation of articulated body regions, starting from multiple in vivo volume scans of a specific individual. In order to solve the correspondence problem across volume scans, a template volume is registered to each sample. The wide range of pose variations is first approximated by volume blend deformation (VBD), providing proper initialization of the articulated subject in different poses. A novel registration method is presented to efficiently reduce the computation cost while avoiding strong local minima inherent in complex articulated body volume registration. The algorithm highly constrains the degrees of freedom and search space involved in the nonlinear optimization, using hierarchical volume structures and locally constrained deformation based on the biharmonic clamped spline. Our registration step establishes a correspondence across scans, allowing a data-driven deformation approach in the volume domain. The results provide an occlusion-free person-specific 3D human body model, asymptotically accurate inner tissue deformations, and realistic volume animation of articulated movements driven by standard joint control estimated from the actual skeleton. Our approach also addresses the practical issues arising in using scans from living subjects. The robustness of our algorithms is tested by their applications on the hand, probably the most complex articulated region in the body, and the knee, a frequent subject area for medical imaging due to injuries. © 2011 IEEE

  2. 3D Registration of mpMRI for Assessment of Prostate Cancer Focal Therapy.

    Science.gov (United States)

    Orczyk, Clément; Rosenkrantz, Andrew B; Mikheev, Artem; Villers, Arnauld; Bernaudin, Myriam; Taneja, Samir S; Valable, Samuel; Rusinek, Henry

    2017-12-01

    This study aimed to assess a novel method of three-dimensional (3D) co-registration of prostate magnetic resonance imaging (MRI) examinations performed before and after prostate cancer focal therapy. We developed a software platform for automatic 3D deformable co-registration of prostate MRI at different time points and applied this method to 10 patients who underwent focal ablative therapy. MRI examinations were performed preoperatively, as well as 1 week and 6 months post treatment. Rigid registration served as reference for assessing co-registration accuracy and precision. Segmentation of preoperative and postoperative prostate revealed a significant postoperative volume decrease of the gland that averaged 6.49 cc (P = .017). Applying deformable transformation based on mutual information from 120 pairs of MRI slices, we refined by 2.9 mm (max. 6.25 mm) the alignment of the ablation zone, segmented from contrast-enhanced images on the 1-week postoperative examination, to the 6-month postoperative T2-weighted images. This represented a 500% improvement over the rigid approach (P = .001), corrected by volume. The dissimilarity by Dice index of the mapped ablation zone using deformable transformation vs rigid control was significantly (P = .04) higher at the ablation site than in the whole gland. Our findings illustrate our method's ability to correct for deformation at the ablation site. The preliminary analysis suggests that deformable transformation computed from mutual information of preoperative and follow-up MRI is accurate in co-registration of MRI examinations performed before and after focal therapy. The ability to localize the previously ablated tissue in 3D space may improve targeting for image-guided follow-up biopsy within focal therapy protocols. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  3. Error estimation of deformable image registration of pulmonary CT scans using convolutional neural networks.

    Science.gov (United States)

    Eppenhof, Koen A J; Pluim, Josien P W

    2018-04-01

    Error estimation in nonlinear medical image registration is a nontrivial problem that is important for validation of registration methods. We propose a supervised method for estimation of registration errors in nonlinear registration of three-dimensional (3-D) images. The method is based on a 3-D convolutional neural network that learns to estimate registration errors from a pair of image patches. By applying the network to patches centered around every voxel, we construct registration error maps. The network is trained using a set of representative images that have been synthetically transformed to construct a set of image pairs with known deformations. The method is evaluated on deformable registrations of inhale-exhale pairs of thoracic CT scans. Using ground truth target registration errors on manually annotated landmarks, we evaluate the method's ability to estimate local registration errors. Estimation of full domain error maps is evaluated using a gold standard approach. The two evaluation approaches show that we can train the network to robustly estimate registration errors in a predetermined range, with subvoxel accuracy. We achieved a root-mean-square deviation of 0.51 mm from gold standard registration errors and of 0.66 mm from ground truth landmark registration errors.

  4. 75 FR 8339 - Difenzoquat; Product Cancellation Order for Certain Pesticide Registrations

    Science.gov (United States)

    2010-02-24

    ... products identified in Table 1 of Unit II in a manner inconsistent with any of the Provisions for... registrant listed in Table 1 to voluntarily cancel these product registrations. These are the last products... are listed in sequence by registration number in Table 1 of this unit. Table 1. -- Difenzoquat Product...

  5. Practical and conceptual issues of clinical trial registration for Brazilian researchers

    Directory of Open Access Journals (Sweden)

    Carolina Gomes Freitas

    Full Text Available CONTEXT AND OBJECTIVE: Clinical trial registration is a prerequisite for publication in respected scientific journals. Recent Brazilian regulations also require registration of some clinical trials in the Brazilian Clinical Trials Registry (ReBEC but there is little information available about practical issues involved in the registration process. This article discusses the importance of clinical trial registration and the practical issues involved in this process. DESIGN AND SETTING: Descriptive study conducted by researchers within a postgraduate program at a public university in São Paulo, Brazil. METHODS: Information was obtained from clinical trial registry platforms, article reference lists and websites (last search: September 2014 on the following topics: definition of a clinical trial, history, purpose and importance of registry platforms, the information that should be registered and the registration process. RESULTS: Clinical trial registration aims to avoid publication bias and is required by Brazilian journals indexed in LILACS and SciELO and by journals affiliated to the International Committee of Medical Journal Editors (ICMJE. Recent Brazilian regulations require that all clinical trials (phases I to IV involving new drugs to be marketed in this country must be registered in ReBEC. The pros and cons of using different clinical trial registration platforms are discussed. CONCLUSIONS: Clinical trial registration is important and various mechanisms to enforce its implementation now exist. Researchers should take into account national regulations and publication requirements when choosing the platform on which they will register their trial.

  6. A Harmonic Current Suppression Control Strategy for Droop-Controlled Inverter Connected to the Distorted Grid

    DEFF Research Database (Denmark)

    Wei, Feng; Sun, Kai; Guan, Yajuan

    2015-01-01

    currents. Therefore, the reason of generation of distorted grid-feeding current of GF-VCI under the distorted grid voltage is investigated firstly in this paper. Then, a harmonic grid-feeding current suppression control strategy for GF-VCI is proposed. Two different filters are compared and analysed before...... voltage component at the point of common coupling. As a result, the difference of harmonic voltage between PCC and GF-VCI is reduced and the THDi of grid feeding-currents is decreased. Finally, the proposed control strategy is verified through simulations and experimental results....

  7. Adaptive Hysteresis Band Current Control for Transformerless Single-Phase PV Inverters

    DEFF Research Database (Denmark)

    Vázquez, Gerardo; Rodriguez, Pedro; Ordoñez, Rafael

    2009-01-01

    Current control based on hysteresis algorithms are widely used in different applications, such as motion control, active filtering or active/reactive power delivery control in distributed generation systems. The hysteresis current control provides to the system a fast and robust dynamic response......, and requires a simple implementation in standard digital signal platforms. On the other hand, the main drawback of classical hysteresis current control lies in the fact that the switching frequency is variable, as the hysteresis band is fixed. In this paper a variable band hysteresis control algorithm...... different single-phase PV inverter topologies, by means of simulations performed with PSIM. In addition, the behavior of the thermal losses when using each control structure in such converters has been studied as well....

  8. Optimization strategies for ultrasound volume registration

    International Nuclear Information System (INIS)

    Ijaz, Umer Zeeshan; Prager, Richard W; Gee, Andrew H; Treece, Graham M

    2010-01-01

    This paper considers registration of 3D ultrasound volumes acquired in multiple views for display in a single image volume. One way to acquire 3D data is to use a mechanically swept 3D probe. However, the usefulness of these probes is restricted by their limited field of view. This problem can be overcome by attaching a six-degree-of-freedom (DOF) position sensor to the probe, and displaying the information from multiple sweeps in their proper positions. However, an external six-DOF position sensor can be an inconvenience in a clinical setting. The objective of this paper is to propose a hybrid strategy that replaces the sensor with a combination of three-DOF image registration and an unobtrusive inertial sensor for measuring orientation. We examine a range of optimization algorithms and similarity measures for registration and compare them in in vitro and in vivo experiments. We register based on multiple reslice images rather than a whole voxel array. In this paper, we use a large number of reslices for improved reliability at the expense of computational speed. We have found that the Levenberg–Marquardt method is very fast but is not guaranteed to give the correct solution all the time. We conclude that normalized mutual information used in the Nelder–Mead simplex algorithm is potentially suitable for the registration task with an average execution time of around 5 min, in the majority of cases, with two restarts in a C++ implementation on a 3.0 GHz Intel Core 2 Duo CPU machine

  9. Edge-based correlation image registration for multispectral imaging

    Science.gov (United States)

    Nandy, Prabal [Albuquerque, NM

    2009-11-17

    Registration information for images of a common target obtained from a plurality of different spectral bands can be obtained by combining edge detection and phase correlation. The images are edge-filtered, and pairs of the edge-filtered images are then phase correlated to produce phase correlation images. The registration information can be determined based on these phase correlation images.

  10. Computing homography with RANSAC algorithm: a novel method of registration

    Science.gov (United States)

    Li, Xiaowei; Liu, Yue; Wang, Yongtian; Yan, Dayuan

    2005-02-01

    An AR (Augmented Reality) system can integrate computer-generated objects with the image sequences of real world scenes in either an off-line or a real-time way. Registration, or camera pose estimation, is one of the key techniques to determine its performance. The registration methods can be classified as model-based and move-matching. The former approach can accomplish relatively accurate registration results, but it requires the precise model of the scene, which is hard to be obtained. The latter approach carries out registration by computing the ego-motion of the camera. Because it does not require the prior-knowledge of the scene, its registration results sometimes turn out to be less accurate. When the model defined is as simple as a plane, a mixed method is introduced to take advantages of the virtues of the two methods mentioned above. Although unexpected objects often occlude this plane in an AR system, one can still try to detect corresponding points with a contract-expand method, while this will import erroneous correspondences. Computing homography with RANSAC algorithm is used to overcome such shortcomings. Using the robustly estimated homography resulted from RANSAC, the camera projective matrix can be recovered and thus registration is accomplished even when the markers are lost in the scene.

  11. Can the UK's birth registration system better serve the interests of those born following collaborative assisted reproduction?

    Science.gov (United States)

    Crawshaw, Marilyn A; Blyth, Eric D; Feast, Julia

    2017-06-01

    Current birth registration systems fail to serve adequately the interests of those born as a result of gamete and embryo donation and surrogacy. In the UK, changes to the birth registration system have been piecemeal, reactive and situation-specific and no information is recorded about gamete donors. Birth registration has thereby become a statement of legal parentage and citizenship only, without debate as to whether it should serve any wider functions. This sits uneasily with the increasingly accepted human right to know one's genetic and gestational as well as legal parents, and the duty of the State to facilitate that right. This commentary sets out one possible model for reform to better ensure that those affected become aware of, and/or have access to, knowledge about their origins and that such information is stored and released effectively without compromising individual privacy. Among other features, our proposal links the birth registration system and the information stored in the Human Fertilization and Embryology Authority's Register of Information, although further work than we have been able to undertake here is necessary to ensure a better fit where cross-border treatment services or informal arrangements have been involved. The time for debate and reform is well overdue.

  12. Integration of breathing in radiotherapy: contribution of the image deformable registration

    International Nuclear Information System (INIS)

    Boldea, Vlad

    2006-01-01

    As taking organ movements and deformations into account in radiotherapy for the treatment of lung cancer is a challenge as it allows the delivered dose to be increased while better sparing surrounding sane tissues, this research thesis addresses non-rigid (or deformable) registration iconic methods applied to thorax X ray computed tomography (X-ray CT) 3D acquisitions. The objective is to extract the information regarding lung and tumour movement and deformation. The author thus reports the development of deformable registration framework with several methods of regularisation of vector fields. Three main studies have been performed and are reported. In the first one, deformable registration allowed the breathe blockage reproducibility to be controlled. Experiments performed on ten patients showed that this blockage is efficient (displacement less than 5 mm), except for three of them with functional anomalies. In a second study, 4D X-ray CT acquisitions (3D X-ray CT images acquired at different moments of the normal breathing cycle) have been analysed to extract and follow thorax movements and deformations in order to take them into account in free breathing and to perform 4D dynamic dosimetric studies. A first 4D X-ray CT image model has been developed from 3D X-ray CT images acquired in breathe blockage at the end of expiration and at the end on inhalation [fr

  13. Alternative face models for 3D face registration

    Science.gov (United States)

    Salah, Albert Ali; Alyüz, Neşe; Akarun, Lale

    2007-01-01

    3D has become an important modality for face biometrics. The accuracy of a 3D face recognition system depends on a correct registration that aligns the facial surfaces and makes a comparison possible. The best results obtained so far use a one-to-all registration approach, which means each new facial surface is registered to all faces in the gallery, at a great computational cost. We explore the approach of registering the new facial surface to an average face model (AFM), which automatically establishes correspondence to the pre-registered gallery faces. Going one step further, we propose that using a couple of well-selected AFMs can trade-off computation time with accuracy. Drawing on cognitive justifications, we propose to employ category-specific alternative average face models for registration, which is shown to increase the accuracy of the subsequent recognition. We inspect thin-plate spline (TPS) and iterative closest point (ICP) based registration schemes under realistic assumptions on manual or automatic landmark detection prior to registration. We evaluate several approaches for the coarse initialization of ICP. We propose a new algorithm for constructing an AFM, and show that it works better than a recent approach. Finally, we perform simulations with multiple AFMs that correspond to different clusters in the face shape space and compare these with gender and morphology based groupings. We report our results on the FRGC 3D face database.

  14. Comparison of manual vs. automated multimodality (CT-MRI) image registration for brain tumors

    International Nuclear Information System (INIS)

    Sarkar, Abhirup; Santiago, Roberto J.; Smith, Ryan; Kassaee, Alireza

    2005-01-01

    Computed tomgoraphy-magnetic resonance imaging (CT-MRI) registrations are routinely used for target-volume delineation of brain tumors. We clinically use 2 software packages based on manual operation and 1 automated package with 2 different algorithms: chamfer matching using bony structures, and mutual information using intensity patterns. In all registration algorithms, a minimum of 3 pairs of identical anatomical and preferably noncoplanar landmarks is used on each of the 2 image sets. In manual registration, the program registers these points and links the image sets using a 3-dimensional (3D) transformation. In automated registration, the 3 landmarks are used as an initial starting point and further processing is done to complete the registration. Using our registration packages, registration of CT and MRI was performed on 10 patients. We scored the results of each registration set based on the amount of time spent, the accuracy reported by the software, and a final evaluation. We evaluated each software program by measuring the residual error between 'matched' points on the right and left globes and the posterior fossa for fused image slices. In general, manual registration showed higher misalignment between corresponding points compared to automated registration using intensity matching. This error had no directional dependence and was, most of the time, larger for a larger structure in both registration techniques. Automated algorithm based on intensity matching also gave the best results in terms of registration accuracy, irrespective of whether or not the initial landmarks were chosen carefully, when compared to that done using bone matching algorithm. Intensity-matching algorithm required the least amount of user-time and provided better accuracy

  15. Control of optically induced currents in semiconductor crystals

    Energy Technology Data Exchange (ETDEWEB)

    Kohli, Kapil Kumar

    2010-06-01

    The generation and control of optically induced currents has the potential to become an important building block for optical computers. Here, shift and rectification currents are investigated that emerge from a divergence of the optical susceptibility. It is known that these currents react to the shape of the impinging laser pulse, and especially to the shape of the pulse envelope. The main goal is the systematic manipulation of the pulse envelope with an optical pulse shaper that is integrated into a standard THz emission setup. The initial approach, the chirping of the laser pulse only has a weak influence on the envelope and the currents. Instead, a second approach is suggested that uses the combined envelope of a phase-stable pulse-pair as a parameter. In a laser pulse, the position of the maxima of the electrical field and the pulse envelope are shifted relative to each other. This shift is known as the Carrier-Envelope Phase (CEP). It is a new degree of freedom that is usually only accessible in specially stabilized systems. It is shown, that in a phase-stable pulse-pair, at least the relative CEP is usable as a new degree of freedom. It has a great influence on the shape of the pulse envelope and thus on the current density. It is shown that this approach enables the coherent control of the current density. The experiments are corroborated by a theoretical model of the system. The potential of this approach is demonstrated in an application. A framework is presented that uses an iterative genetic algorithm to create arbitrarily shaped THz traces. The algorithm controls the optical pulse shaper, and varies the phase of the impinging laser pulses until the desired target trace is found. (orig.)

  16. S-HAMMER: hierarchical attribute-guided, symmetric diffeomorphic registration for MR brain images.

    Science.gov (United States)

    Wu, Guorong; Kim, Minjeong; Wang, Qian; Shen, Dinggang

    2014-03-01

    Deformable registration has been widely used in neuroscience studies for spatial normalization of brain images onto the standard space. Because of possible large anatomical differences across different individual brains, registration performance could be limited when trying to estimate a single directed deformation pathway, i.e., either from template to subject or from subject to template. Symmetric image registration, however, offers an effective way to simultaneously deform template and subject images toward each other until they meet at the middle point. Although some intensity-based registration algorithms have nicely incorporated this concept of symmetric deformation, the pointwise intensity matching between two images may not necessarily imply the matching of correct anatomical correspondences. Based on HAMMER registration algorithm (Shen and Davatzikos, [2002]: IEEE Trans Med Imaging 21:1421-1439), we integrate the strategies of hierarchical attribute matching and symmetric diffeomorphic deformation to build a new symmetric-diffeomorphic HAMMER registration algorithm, called as S-HAMMER. The performance of S-HAMMER has been extensively compared with 14 state-of-the-art nonrigid registration algorithms evaluated in (Klein et al., [2009]: NeuroImage 46:786-802) by using real brain images in LPBA40, IBSR18, CUMC12, and MGH10 datasets. In addition, the registration performance of S-HAMMER, by comparison with other methods, is also demonstrated on both elderly MR brain images (>70 years old) and the simulated brain images with ground-truth deformation fields. In all experiments, our proposed method achieves the best registration performance over all other registration methods, indicating the high applicability of our method in future neuroscience and clinical applications. Copyright © 2013 Wiley Periodicals, Inc.

  17. Registration of TLS and MLS Point Cloud Combining Genetic Algorithm with ICP

    Directory of Open Access Journals (Sweden)

    YAN Li

    2018-04-01

    Full Text Available Large scene point cloud can be quickly acquired by mobile laser scanning (MLS technology,which needs to be supplemented by terrestrial laser scanning (TLS point cloud because of limited field of view and occlusion.MLS and TLS point cloud are located in geodetic coordinate system and local coordinate system respectively.This paper proposes an automatic registration method combined genetic algorithm (GA and iterative closed point ICP to achieve a uniform coordinate reference frame.The local optimizer is utilized in ICP.The efficiency of ICP is higher than that of GA registration,but it depends on a initial solution.GA is a global optimizer,but it's inefficient.The combining strategy is that ICP is enabled to complete the registration when the GA tends to local search.The rough position measured by a built-in GPS of a terrestrial laser scanner is used in the GA registration to limit its optimizing search space.To improve the GA registration accuracy,a maximum registration model called normalized sum of matching scores (NSMS is presented.The results for measured data show that the NSMS model is effective,the root mean square error (RMSE of GA registration is 1~5 cm and the registration efficiency can be improved by about 50% combining GA with ICP.

  18. A fault-tolerant strategy based on SMC for current-controlled converters

    Science.gov (United States)

    Azer, Peter M.; Marei, Mostafa I.; Sattar, Ahmed A.

    2018-05-01

    The sliding mode control (SMC) is used to control variable structure systems such as power electronics converters. This paper presents a fault-tolerant strategy based on the SMC for current-controlled AC-DC converters. The proposed SMC is based on three sliding surfaces for the three legs of the AC-DC converter. Two sliding surfaces are assigned to control the phase currents since the input three-phase currents are balanced. Hence, the third sliding surface is considered as an extra degree of freedom which is utilised to control the neutral voltage. This action is utilised to enhance the performance of the converter during open-switch faults. The proposed fault-tolerant strategy is based on allocating the sliding surface of the faulty leg to control the neutral voltage. Consequently, the current waveform is improved. The behaviour of the current-controlled converter during different types of open-switch faults is analysed. Double switch faults include three cases: two upper switch fault; upper and lower switch fault at different legs; and two switches of the same leg. The dynamic performance of the proposed system is evaluated during healthy and open-switch fault operations. Simulation results exhibit the various merits of the proposed SMC-based fault-tolerant strategy.

  19. Automated dental implantation using image-guided robotics: registration results.

    Science.gov (United States)

    Sun, Xiaoyan; McKenzie, Frederic D; Bawab, Sebastian; Li, Jiang; Yoon, Yongki; Huang, Jen-K

    2011-09-01

    One of the most important factors affecting the outcome of dental implantation is the accurate insertion of the implant into the patient's jaw bone, which requires a high degree of anatomical accuracy. With the accuracy and stability of robots, image-guided robotics is expected to provide more reliable and successful outcomes for dental implantation. Here, we proposed the use of a robot for drilling the implant site in preparation for the insertion of the implant. An image-guided robotic system for automated dental implantation is described in this paper. Patient-specific 3D models are reconstructed from preoperative Cone-beam CT images, and implantation planning is performed with these virtual models. A two-step registration procedure is applied to transform the preoperative plan of the implant insertion into intra-operative operations of the robot with the help of a Coordinate Measurement Machine (CMM). Experiments are carried out with a phantom that is generated from the patient-specific 3D model. Fiducial Registration Error (FRE) and Target Registration Error (TRE) values are calculated to evaluate the accuracy of the registration procedure. FRE values are less than 0.30 mm. Final TRE values after the two-step registration are 1.42 ± 0.70 mm (N = 5). The registration results of an automated dental implantation system using image-guided robotics are reported in this paper. Phantom experiments show that the practice of robot in the dental implantation is feasible and the system accuracy is comparable to other similar systems for dental implantation.

  20. 76 FR 10291 - Amendment to the International Traffic in Arms Regulations: Electronic Payment of Registration...

    Science.gov (United States)

    2011-02-24

    ..., Bureau of Political Military Affairs, U.S. Department of State, Washington, DC 20522-0112. Persons with... DS-2032, Statement of Registration, submission) certifying criminal history, eligibility, and foreign... Office: Bureau of Political-Military Affairs, Directorate of Defense Trade Controls, PM/DDTC. Form Number...

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