WorldWideScience

Sample records for reference system undergoes

  1. Dose audit for patients undergoing two common radiography examinations with digital radiology systems.

    Science.gov (United States)

    İnal, Tolga; Ataç, Gökçe

    2014-01-01

    We aimed to determine the radiation doses delivered to patients undergoing general examinations using computed or digital radiography systems in Turkey. Radiographs of 20 patients undergoing posteroanterior chest X-ray and of 20 patients undergoing anteroposterior kidney-ureter-bladder radiography were evaluated in five X-ray rooms at four local hospitals in the Ankara region. Currently, almost all radiology departments in Turkey have switched from conventional radiography systems to computed radiography or digital radiography systems. Patient dose was measured for both systems. The results were compared with published diagnostic reference levels (DRLs) from the European Union and International Atomic Energy Agency. The average entrance surface doses (ESDs) for chest examinations exceeded established international DRLs at two of the X-ray rooms in a hospital with computed radiography. All of the other ESD measurements were approximately equal to or below the DRLs for both examinations in all of the remaining hospitals. Improper adjustment of the exposure parameters, uncalibrated automatic exposure control systems, and failure of the technologists to choose exposure parameters properly were problems we noticed during the study. This study is an initial attempt at establishing local DRL values for digital radiography systems, and will provide a benchmark so that the authorities can establish reference dose levels for diagnostic radiology in Turkey.

  2. Dose audit for patients undergoing two common radiography examinations with digital radiology systems

    Science.gov (United States)

    İnal, Tolga; Ataç, Gökçe

    2014-01-01

    PURPOSE We aimed to determine the radiation doses delivered to patients undergoing general examinations using computed or digital radiography systems in Turkey. MATERIALS AND METHODS Radiographs of 20 patients undergoing posteroanterior chest X-ray and of 20 patients undergoing anteroposterior kidney-ureter-bladder radiography were evaluated in five X-ray rooms at four local hospitals in the Ankara region. Currently, almost all radiology departments in Turkey have switched from conventional radiography systems to computed radiography or digital radiography systems. Patient dose was measured for both systems. The results were compared with published diagnostic reference levels (DRLs) from the European Union and International Atomic Energy Agency. RESULTS The average entrance surface doses (ESDs) for chest examinations exceeded established international DRLs at two of the X-ray rooms in a hospital with computed radiography. All of the other ESD measurements were approximately equal to or below the DRLs for both examinations in all of the remaining hospitals. Improper adjustment of the exposure parameters, uncalibrated automatic exposure control systems, and failure of the technologists to choose exposure parameters properly were problems we noticed during the study. CONCLUSION This study is an initial attempt at establishing local DRL values for digital radiography systems, and will provide a benchmark so that the authorities can establish reference dose levels for diagnostic radiology in Turkey. PMID:24317331

  3. Dose study in pediatric patients undergoing cardiac procedures in a digital system

    International Nuclear Information System (INIS)

    Ordonez Marquez, J.; Huertas Martinez, C.; Luquero Llopis, N.; Vano Carruana, E.; Corredoira, S.; Huerga Cabrerizo, C.; Plaza Aparicio, R.; Tellez-Cepeda Ruiz, M.

    2011-01-01

    In La Paz Hospital in Madrid has recently installed a biplane x-ray equipment in the Department of Pediatric Cardiology. It is a digital system equipped with two amorphous silicon detectors. There has been a characterization of the equipment prior to commissioning for clinical use. It was later followed up on the dose delivered to pediatric patients undergoing various diagnostic and therapeutic procedures. Yet the absence of reference values for interventional cardiology child dose, the values obtained were used to establish baseline dose by age group that will serve as initial references and allow our radiation dose compared with those of other centers and check that the skin dose are in most cases below the thresholds for deterministic effects.

  4. Space-Time Reference Systems

    CERN Document Server

    Soffel, Michael

    2013-01-01

    The high accuracy of modern astronomical spatial-temporal reference systems has made them considerably complex. This book offers a comprehensive overview of such systems. It begins with a discussion of ‘The Problem of Time’, including recent developments in the art of clock making (e.g., optical clocks) and various time scales. The authors address  the definitions and realization of spatial coordinates by reference to remote celestial objects such as quasars. After an extensive treatment of classical equinox-based coordinates, new paradigms for setting up a celestial reference system are introduced that no longer refer to the translational and rotational motion of the Earth. The role of relativity in the definition and realization of such systems is clarified. The topics presented in this book are complemented by exercises (with solutions). The authors offer a series of files, written in Maple, a standard computer algebra system, to help readers get a feel for the various models and orders of magnitude. ...

  5. Exercise may reduce depression but not anxiety in self-referred cancer patients undergoing chemotherapy. Post-hoc analysis of data from the 'Body & Cancer' trial

    DEFF Research Database (Denmark)

    Midtgaard, Julie; Stage, Maria; Møller, Tom

    2011-01-01

    Abstract Background. The diagnosis and treatment of cancer may cause clinically significant and persistent psychological morbidity. The objective of this study was to determine the short-term effect of a six week exercise intervention on anxiety and depression in cancer patients undergoing.......021). Conclusion. Anti-depressant effects could be caused by exercise in self-referred cancer patients undergoing chemotherapy. Dedicated trials and follow-up studies are needed to clarify the optimal duration and content of exercise interventions to meet the needs of clinically depressive or anxious patients....... chemotherapy (The 'Body & Cancer' trial). Methods. Two hundred and nine self-referred patients (52 males, 157 females, mean age 47 years) were randomised into an intervention group and a waiting-list control group. Anxiety and depression was measured by the Hospital Anxiety and Depression Scale. Results...

  6. Korean Reference HLW Disposal System

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Heui Joo; Lee, J. Y.; Kim, S. S. (and others)

    2008-03-15

    This report outlines the results related to the development of Korean Reference Disposal System for High-level radioactive wastes. The research has been supported around for 10 years through a long-term research plan by MOST. The reference disposal method was selected via the first stage of the research during which the technical guidelines for the geological disposal of HLW were determined too. At the second stage of the research, the conceptual design of the reference disposal system was made. For this purpose the characteristics of the reference spent fuels from PWR and CANDU reactors were specified, and the material and specifications of the canisters were determined in term of structural analysis and manufacturing capability in Korea. Also, the mechanical and chemical characteristics of the domestic Ca-bentonite were analyzed in order to supply the basic design parameters of the buffer. Based on these parameters the thermal and mechanical analysis of the near-field was carried out. Thermal-Hydraulic-Mechanical behavior of the disposal system was analyzed. The reference disposal system was proposed through the second year research. At the final third stage of the research, the Korean Reference disposal System including the engineered barrier, surface facilities, and underground facilities was proposed through the performance analysis of the disposal system.

  7. The Spallation Neutron Source RF Reference System

    CERN Document Server

    Piller, Maurice; Crofford, Mark; Doolittle, Lawrence; Ma, Hengjie

    2005-01-01

    The Spallation Neutron Source (SNS) RF Reference System includes the master oscillator (MO), local oscillator(LO) distribution, and Reference RF distribution systems. Coherent low noise Reference RF signals provide the ability to control the phase relationships between the fields in the front-end and linear accelerator (linac) RF cavity structures. The SNS RF Reference System requirements, implementation details, and performance are discussed.

  8. Organ doses for reference pediatric and adolescent patients undergoing computed tomography estimated by Monte Carlo simulation

    International Nuclear Information System (INIS)

    Lee, Choonsik; Kim, Kwang Pyo; Long, Daniel J.; Bolch, Wesley E.

    2012-01-01

    Purpose: To establish an organ dose database for pediatric and adolescent reference individuals undergoing computed tomography (CT) examinations by using Monte Carlo simulation. The data will permit rapid estimates of organ and effective doses for patients of different age, gender, examination type, and CT scanner model. Methods: The Monte Carlo simulation model of a Siemens Sensation 16 CT scanner previously published was employed as a base CT scanner model. A set of absorbed doses for 33 organs/tissues normalized to the product of 100 mAs and CTDI vol (mGy/100 mAs mGy) was established by coupling the CT scanner model with age-dependent reference pediatric hybrid phantoms. A series of single axial scans from the top of head to the feet of the phantoms was performed at a slice thickness of 10 mm, and at tube potentials of 80, 100, and 120 kVp. Using the established CTDI vol - and 100 mAs-normalized dose matrix, organ doses for different pediatric phantoms undergoing head, chest, abdomen-pelvis, and chest-abdomen-pelvis (CAP) scans with the Siemens Sensation 16 scanner were estimated and analyzed. The results were then compared with the values obtained from three independent published methods: CT-Expo software, organ dose for abdominal CT scan derived empirically from patient abdominal circumference, and effective dose per dose-length product (DLP). Results: Organ and effective doses were calculated and normalized to 100 mAs and CTDI vol for different CT examinations. At the same technical setting, dose to the organs, which were entirely included in the CT beam coverage, were higher by from 40 to 80% for newborn phantoms compared to those of 15-year phantoms. An increase of tube potential from 80 to 120 kVp resulted in 2.5-2.9-fold greater brain dose for head scans. The results from this study were compared with three different published studies and/or techniques. First, organ doses were compared to those given by CT-Expo which revealed dose differences up to

  9. Positional reference system for ultraprecision machining

    International Nuclear Information System (INIS)

    Arnold, J.B.; Burleson, R.R.; Pardue, R.M.

    1982-01-01

    A stable positional reference system for use in improving the cutting tool-to-part contour position in numerical controlledmultiaxis metal turning machines is provided. The reference system employs a plurality of interferometers referenced to orthogonally disposed metering bars which are substantially isolated from machine strain induced position errors for monitoring the part and tool positions relative to the metering bars. A microprocessor-based control system is employed in conjunction with the plurality of position interferometers and part contour description data inputs to calculate error components for each axis of movement and output them to corresponding axis drives with appropriate scaling and error compensation. Real-time position control, operating in combination with the reference system, makes possible the positioning of the cutting points of a tool along a part locus with a substantially greater degree of accuracy than has been attained previously in the art by referencing and then monitoring only the tool motion relative to a reference position located on the machine base

  10. Positional reference system for ultraprecision machining

    Science.gov (United States)

    Arnold, J.B.; Burleson, R.R.; Pardue, R.M.

    1980-09-12

    A stable positional reference system for use in improving the cutting tool-to-part contour position in numerical controlled-multiaxis metal turning machines is provided. The reference system employs a plurality of interferometers referenced to orthogonally disposed metering bars which are substantially isolated from machine strain induced position errors for monitoring the part and tool positions relative to the metering bars. A microprocessor-based control system is employed in conjunction with the plurality of positions interferometers and part contour description data input to calculate error components for each axis of movement and output them to corresponding axis driven with appropriate scaling and error compensation. Real-time position control, operating in combination with the reference system, makes possible the positioning of the cutting points of a tool along a part locus with a substantially greater degree of accuracy than has been attained previously in the art by referencing and then monitoring only the tool motion relative to a reference position located on the machine base.

  11. Expert Systems in Reference Services.

    Science.gov (United States)

    Roysdon, Christine, Ed.; White, Howard D., Ed.

    1989-01-01

    Eleven articles introduce expert systems applications in library and information science, and present design and implementation issues of system development for reference services. Topics covered include knowledge based systems, prototype development, the use of artificial intelligence to remedy current system inadequacies, and an expert system to…

  12. Antares Reference Telescope System

    International Nuclear Information System (INIS)

    Viswanathan, V.K.; Kaprelian, E.; Swann, T.; Parker, J.; Wolfe, P.; Woodfin, G.; Knight, D.

    1983-01-01

    Antares is a 24-beam, 40-TW carbon-dioxide laser-fusion system currently nearing completion at the Los Alamos National Laboratory. The 24 beams will be focused onto a tiny target (typically 300 to 1000 μm in diameter) located approximately at the center of a 7.3-m-diameter by 9.3-m-long vacuum (10 - 6 torr) chamber. The design goal is to position the targets to within 10 μm of a selected nominal position, which may be anywhere within a fixed spherical region 1 cm in diameter. The Antares Reference Telescope System is intended to help achieve this goal for alignment and viewing of the various targets used in the laser system. The Antares Reference Telescope System consists of two similar electro-optical systems positioned in a near orthogonal manner in the target chamber area of the laser. Each of these consists of four subsystems: (1) a fixed 9X optical imaging subsystem which produces an image of the target at the vidicon; (2) a reticle projection subsystem which superimposes an image of the reticle pattern at the vidicon; (3) an adjustable front-lighting subsystem which illuminates the target; and (4) an adjustable back-lighting subsystem which also can be used to illuminate the target. The various optical, mechanical, and vidicon design considerations and trade-offs are discussed. The final system chosen (which is being built) and its current status are described in detail

  13. Study of alloy crystallization in systems undergoing peritectic transformations

    International Nuclear Information System (INIS)

    Psarev, V.I.; Kirij, V.G.; Kuznetsov, A.V.; Psareva, I.V.; Ivanov, A.L.

    1982-01-01

    Studies into Ge-Te, In-Te, Al-Mn, Sb-Zn, Sn-Au systems are carried out at melt cooling rates from 50 deg/h to 10 5 deg/h to establish regularities in stable and metastable crystallization of alloys undergoing peritectic transformations. Methods of metallographic, X-ray phase and X-ray diffraction analyses are used. Differentiation in types of peritectic transformations is made through their mechanisms under equilibrium and non-equilibrium crystallization conditions for various alloy systems. It is found out that ability to supercooling even at low or moderate cooling rates for Te-Ge and Te-In system melts can be one of the main indication of the possibility of amorphous alloy formation [ru

  14. The CEBAF fiber optic phase reference system

    International Nuclear Information System (INIS)

    Crawford, K.; Simrock, S.; Hovater, C.; Krycuk, A.

    1995-01-01

    The specified phase stability of the CEBAF RF distribution system is 2.9 degree rms per linac. Stability is achieved through the use of a temperature and pressure regulated coaxial drive line. Purpose of the fiber optic phase reference system is to monitor the relative phase at the beginning and ending of this drive line, between linacs, injector and separator to determine drift due to ambient temperature fluctuations. The system utilizes an Ortel 1310 nm single mode laser driving Sumitumo optical fiber to distribute a reference signal at 1497 MHz. Phase of this reference signal is compared to the 1427 MHz (LO) and the 70 MHz (IF) via a 360 degree phase detector. The detected information is then routed to the CEBAF control system for display with a specified resolution of ±0.2 degree over a 20 degree phase delta

  15. On the invariance of world time reference system

    International Nuclear Information System (INIS)

    Asanov, G.S.

    1978-01-01

    A universal reference system is studied. It is shown that time differentiation acquires an invariant meaning in the covariant theory of a curved space-time. All the principal covariant equations of the Einstein gravitational field theory can be interpreted successively relative to a universal reference system, whose base congruence is the S-congruence. The Lorentz calibration conditions determine the base tetrades of the universal reference system with an accuracy to rigid spatial rotations with constant coefficients. The use of rigid tetrades eliminates the ambiguity in the interpretation of the value of the energy momentum of a gravitational field

  16. An N+3 Technology Level Reference Propulsion System

    Science.gov (United States)

    Jones, Scott M.; Haller, William J.; Tong, Michael To-Hing

    2017-01-01

    An N+3 technology level engine, suitable as a propulsion system for an advanced single-aisle transport, was developed as a reference cycle for use in technology assessment and decision-making efforts. This reference engine serves three main purposes: it provides thermodynamic quantities at each major engine station, it provides overall propulsion system performance data for vehicle designers to use in their analyses, and it can be used for comparison against other proposed N+3 technology-level propulsion systems on an equal basis. This reference cycle is meant to represent the expected capability of gas turbine engines in the N+3 timeframe given reasonable extrapolations of technology improvements and the ability to take full advantage of those improvements.

  17. Modcomp MAX IV System Processors reference guide

    Energy Technology Data Exchange (ETDEWEB)

    Cummings, J.

    1990-10-01

    A user almost always faces a big problem when having to learn to use a new computer system. The information necessary to use the system is often scattered throughout many different manuals. The user also faces the problem of extracting the information really needed from each manual. Very few computer vendors supply a single Users Guide or even a manual to help the new user locate the necessary manuals. Modcomp is no exception to this, Modcomp MAX IV requires that the user be familiar with the system file usage which adds to the problem. At General Atomics there is an ever increasing need for new users to learn how to use the Modcomp computers. This paper was written to provide a condensed Users Reference Guide'' for Modcomp computer users. This manual should be of value not only to new users but any users that are not Modcomp computer systems experts. This Users Reference Guide'' is intended to provided the basic information for the use of the various Modcomp System Processors necessary to, create, compile, link-edit, and catalog a program. Only the information necessary to provide the user with a basic understanding of the Systems Processors is included. This document provides enough information for the majority of programmers to use the Modcomp computers without having to refer to any other manuals. A lot of emphasis has been placed on the file description and usage for each of the System Processors. This allows the user to understand how Modcomp MAX IV does things rather than just learning the system commands.

  18. An Estimator for Attitude and Heading Reference Systems Based on Virtual Horizontal Reference

    DEFF Research Database (Denmark)

    Wang, Yunlong; Soltani, Mohsen; Hussain, Dil muhammed Akbar

    2016-01-01

    makes it possible to correct the output of roll and pitch of the attitude estimator in the situations without accelerometer measurements, which cannot be achieved by the conventional nonlinear attitude estimator. The performance of VHR is tested both in simulation and hardware environment to validate......The output of the attitude determination systems suffers from large errors in case of accelerometer malfunctions. In this paper, an attitude estimator, based on Virtual Horizontal Reference (VHR), is designed for an Attitude Heading and Reference System (AHRS) to cope with this problem. The VHR...... their estimation performance. Moreover, the hardware test results are compared with that of a high-precision commercial AHRS to verify the estimation results. The implemented algorithm has shown high accuracy of attitude estimation that makes the system suitable for many applications....

  19. 49 CFR 614.101 - Cross-reference to management systems.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Cross-reference to management systems. 614.101... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRANSPORTATION INFRASTRUCTURE MANAGEMENT § 614.101 Cross-reference to management systems. The regulations in 23 CFR Part 500, subparts A and B shall be followed in...

  20. Properties of gravi-inertial systems of reference

    International Nuclear Information System (INIS)

    Dozmorov, I.M.

    1977-01-01

    A number of papers of the author have been summarized devoted to gravi-inertial systems of reference in which the following problems are solved: a) analogs of inertial systems of reference (ISR), gravi-ISR, have been introduced into the general relativity the ory (GRT); b) using transformations between such ISR as symmetry transformation, obtained by variational methods are values with clear physical sense; c) using the gravi-ISR basis as the zero level of the deformation reading, the theory of elasticity in GRT has been constructed and someof its applications considered. The results are compared with those of other authors

  1. weHelp: A Reference Architecture for Social Recommender Systems.

    Science.gov (United States)

    Sheth, Swapneel; Arora, Nipun; Murphy, Christian; Kaiser, Gail

    2010-01-01

    Recommender systems have become increasingly popular. Most of the research on recommender systems has focused on recommendation algorithms. There has been relatively little research, however, in the area of generalized system architectures for recommendation systems. In this paper, we introduce weHelp : a reference architecture for social recommender systems - systems where recommendations are derived automatically from the aggregate of logged activities conducted by the system's users. Our architecture is designed to be application and domain agnostic. We feel that a good reference architecture will make designing a recommendation system easier; in particular, weHelp aims to provide a practical design template to help developers design their own well-modularized systems.

  2. The influence of health care policies and health care system distrust on willingness to undergo genetic testing.

    Science.gov (United States)

    Armstrong, Katrina; Putt, Mary; Halbert, Chanita Hughes; Grande, David; Schwartz, Jerome Sanford; Liao, Kaijun; Marcus, Noora; Demeter, Mirar Bristol; Shea, Judy

    2012-05-01

    As the potential role of genetic testing in disease prevention and management grows, so does concern about differences in uptake of genetic testing across social and racial groups. Characteristics of how genetic tests are delivered may influence willingness to undergo testing and, if they affect population subgroups differently, alter disparities in testing. Conjoint analysis study of the effect of 3 characteristics of genetic test delivery (ie, attributes) on willingness to undergo genetic testing for cancer risk. Data were collected using a random digit dialing survey of 128 African American and 209 white individuals living in the United States. Measures included conjoint scenarios, the Revised Health Care System Distrust Scale (including the values and competence subscales), health insurance coverage, and sociodemographic characteristics. The 3 attributes studied were disclosure of test results to the health insurer, provision of the test by a specialist or primary care doctor, and race-specific or race-neutral marketing. In adjusted analyses, disclosure of test results to insurers, having to get the test from a specialist, and race-specific marketing were all inversely associated with willingness to undergo the genetic test, with the greatest effect for the disclosure attribute. Racial differences in willingness to undergo testing were not statistically significant (P=0.07) and the effect of the attributes on willingness to undergo testing did not vary by patient race. However, the decrease in willingness to undergo testing with insurance disclosure was greater among individuals with high values distrust (P=0.03), and the decrease in willingness to undergo testing from specialist access was smaller among individuals with high competence distrust (P=0.03). Several potentially modifiable characteristics of how genetic tests are delivered are associated with willingness to undergo testing. The effect of 2 of these characteristics vary according to the level of

  3. Standard Relativistic Reference Systems and the IAU Framework

    Science.gov (United States)

    Soffel, Michael H.

    2009-05-01

    The classical post-Newtonian (PN) framework is formulated in one single reference system. In a series of papers Damour, Soffel and Xu laid the foundations for a new improved PN framework dealing with the celestial mechanical problem of N gravitationally interacting rotating bodies of arbitrary shape and the problem of astronomical reference systems. In the DSX-framework a total of N+1 reference systems with corresponding coordinates is introduced in the N-body problem: a global one covering the entire model manifold where the translational equations of motion are formulated and one local system attached to each of the N bodies that is co-moving with the body under consideration. In each of these systems the metric tensor is assumed to be of a special form determined by two potentials: a scalar and a vector potential. Theorems are given for the transformations between local and global coordinates and metric potentials. In each of the local systems outside the local body the metric potentials are expressed in terms of Blanchet-Damour mass- and spin-multipole moments. The talk first introduces the original DSX formalism and then concentrates on IAU resolutions related with it. Finally, the formalism is extended to include also effects from the cosmic expansion. The influence of the Hubble expansion on the dynamics of the solar system is explicitly discussed in some detail.

  4. Light-water reactors reference system classification for the European reliability data system (ERDS)

    International Nuclear Information System (INIS)

    Melis, M.; Mancini, G.

    1982-01-01

    The reference system classification represents a basic stage in the organization of the European reliability data system (ERDS) for light-water reactors, a project actually in development at the Joint Research Centre, Ispra. This project is concerned with operational reliability data collection from the various ''national'' data banks, and centralization in a European reliability data system, so improving the significance of the resulting reliability evaluations. In the framework of the ERDS project, the reference system classification provides a LWR functional break-down and represents a plant-unique identification in the process of homogenization of event-data coming from the various ''national'' organizations. The report, after a brief description of the main objectives of the ERDS project, reviews the criteria followed in the elaboration of the reference system classification; then the detailed classification is presented. The nuclear power station is subdivided in about 180 systems. To each system a sheet is associated, containing: a comprehensive description of system-functions and boundaries; a descritpion of the plant operating mode, linked to the various system functions; a list of the main interface system; and finally, a list of the main components, including type and safety classification

  5. Crew Transportation System Design Reference Missions

    Science.gov (United States)

    Mango, Edward J.

    2015-01-01

    Contains summaries of potential design reference mission goals for systems to transport humans to andfrom low Earth orbit (LEO) for the Commercial Crew Program. The purpose of this document is to describe Design Reference Missions (DRMs) representative of the end-to-end Crew Transportation System (CTS) framework envisioned to successfully execute commercial crew transportation to orbital destinations. The initial CTS architecture will likely be optimized to support NASA crew and NASA-sponsored crew rotation missions to the ISS, but consideration may be given in this design phase to allow for modifications in order to accomplish other commercial missions in the future. With the exception of NASA’s mission to the ISS, the remaining commercial DRMs are notional. Any decision to design or scar the CTS for these additional non-NASA missions is completely up to the Commercial Provider. As NASA’s mission needs evolve over time, this document will be periodically updated to reflect those needs.

  6. Immune genes undergo more adaptive evolution than non-immune system genes in Daphnia pulex

    Directory of Open Access Journals (Sweden)

    McTaggart Seanna J

    2012-05-01

    Full Text Available Abstract Background Understanding which parts of the genome have been most influenced by adaptive evolution remains an unsolved puzzle. Some evidence suggests that selection has the greatest impact on regions of the genome that interact with other evolving genomes, including loci that are involved in host-parasite co-evolutionary processes. In this study, we used a population genetic approach to test this hypothesis by comparing DNA sequences of 30 putative immune system genes in the crustacean Daphnia pulex with 24 non-immune system genes. Results In support of the hypothesis, results from a multilocus extension of the McDonald-Kreitman (MK test indicate that immune system genes as a class have experienced more adaptive evolution than non-immune system genes. However, not all immune system genes show evidence of adaptive evolution. Additionally, we apply single locus MK tests and calculate population genetic parameters at all loci in order to characterize the mode of selection (directional versus balancing in the genes that show the greatest deviation from neutral evolution. Conclusions Our data are consistent with the hypothesis that immune system genes undergo more adaptive evolution than non-immune system genes, possibly as a result of host-parasite arms races. The results of these analyses highlight several candidate loci undergoing adaptive evolution that could be targeted in future studies.

  7. Sourcebook for energy assessment. [Reference Energy Systems for 1972-2020

    Energy Technology Data Exchange (ETDEWEB)

    Beller, M. (ed.)

    1975-12-01

    An analytical approach is presented that is broadly applicable to the assessment of energy technologies and policies. Using the Reference Energy System approach, it permits the examination of the economic, environmental, and resource implications resulting from the substitution of one fuel or technology for another. Included as tools for such analyses are the necessary data and methodology, as well as a set of Reference Energy Systems covering the 1972-2020 period to serve as baselines for the perturbation analyses of interest. 46 tables, 25 figures, 71 references.

  8. Developing a Frame of Reference for understanding configuration systems

    DEFF Research Database (Denmark)

    Ladeby, Klaes Rohde; Edwards, Kasper

    2008-01-01

    This paper uses the theory of technical systems to develop a frame of reference of product configuration systems. Following a definition of the configuration task, product model and product configuration system the theory of technical systems are presented. Configuration systems are then related...

  9. Astronomical relativistic reference systems with multipolar expansion: the global one

    International Nuclear Information System (INIS)

    Xie Yi

    2014-01-01

    With the rapid development of techniques for astronomical observations, the precision of measurements has been significantly increasing. Theories describing astronomical relativistic reference systems, which are the foundation for processing and interpreting these data now and in the future, may require extensions to satisfy the needs of these trends. Besides building a framework compatible with alternative theories of gravity and the pursuit of higher order post-Newtonian approximation, it will also be necessary to make the first order post-Newtonian multipole moments of celestial bodies be explicitly expressed in the astronomical relativistic reference systems. This will bring some convenience into modeling the observations and experiments and make it easier to distinguish different contributions in measurements. As a first step, the global solar system reference system is expressed as a multipolar expansion and the post-Newtonian mass and spin moments are shown explicitly in the metric which describes the coordinates of the system. The full expression of the global metric is given. (research papers)

  10. Data Link Test and Analysis System/ATCRBS Transponder Test System Technical Reference

    Science.gov (United States)

    1990-05-01

    This document references material for personnel using or making software changes : to the Data Link Test and Analysis System (DATAS) for Air Traffic Control Radar : Beacon System (ATCRBS) transponder testing and data collection. This is one of : a se...

  11. Coagulation profile in patients undergoing video-assisted thoracoscopic lobectomy

    DEFF Research Database (Denmark)

    Christensen, Thomas Decker; Vad, Henrik; Pedersen, Søren

    2017-01-01

    -, and the first two days postoperatively by standard coagulation blood test, thromboelastometry (ROTEM®) and thrombin generation. Results: Patients undergoing potential curative surgery for lung cancer were not hypercoagulable preoperatively. There was no statistically significant difference in the majority......Background: Knowledge about the impact of Low-Molecular-Weight Heparin (LMWH) on the coagulation system in patients undergoing minimal invasive lung cancer surgery is sparse. The aim of this study was to assess the effect of LMWH on the coagulation system in patients undergoing Video......-Assisted Thoracoscopic Surgery (VATS) lobectomy for primary lung cancer. Methods: Sixty-three patients diagnosed with primary lung cancer undergoing VATS lobectomy were randomized to either subcutaneous injection with dalteparin (Fragmin®) 5000 IE once daily or no intervention. Coagulation was assessed pre-, peri...

  12. The self-referred mammography patient

    International Nuclear Information System (INIS)

    Reynolds, H.E.; Jackson, V.P.

    1990-01-01

    This paper compares the demographics, knowledge, and attitudes of women who refer themselves for screening mammography with those who undergo mammography on the advice of their physicians. Four hundred eighty-five consecutive mammography patients (437 doctor preferred [DR], 48 self-referred [SR]) completed a survey during their mammography appointment. The sample population contained a wide range of socioeconomic groups. While similar in age, race, and employment status to DR patients, SR patients were significantly more likely to have a family income of more than 30,000 per year, be college graduates, and report that they were in good or excellent health

  13. Discrete Model Reference Adaptive Control System for Automatic Profiling Machine

    Directory of Open Access Journals (Sweden)

    Peng Song

    2012-01-01

    Full Text Available Automatic profiling machine is a movement system that has a high degree of parameter variation and high frequency of transient process, and it requires an accurate control in time. In this paper, the discrete model reference adaptive control system of automatic profiling machine is discussed. Firstly, the model of automatic profiling machine is presented according to the parameters of DC motor. Then the design of the discrete model reference adaptive control is proposed, and the control rules are proven. The results of simulation show that adaptive control system has favorable dynamic performances.

  14. Preoperative renin-angiotensin system inhibitors protect renal function in aging patients undergoing cardiac surgery.

    Science.gov (United States)

    Barodka, Viachaslau; Silvestry, Scott; Zhao, Ning; Jiao, Xiangyin; Whellan, David J; Diehl, James; Sun, Jian-Zhong

    2011-05-15

    Renal failure (RF) represents a major postoperative complication for elderly patients undergoing cardiac surgery. This observational cohort study examines effects of preoperative use of renin-angiotensin system (RAS) inhibitors on postoperative renal failure in aging patients undergoing cardiac surgery. We retrospectively analyzed a cohort of 1287 patients who underwent cardiac surgery at this institution (2003-2007). The patients included were ≥65 years old, scheduled for elective cardiac surgery, and without preexisting RF (defined by the criteria of the Society of Thoracic Surgeons as described in Method). Of all patients evaluated, 346 patients met the inclusion criteria and were divided into two groups: using (n = 122) or not using (n = 224) preoperative RAS inhibitors. A comparison of the two groups showed no significant differences in baseline parameters, including creatinine clearance, body mass index, history of diabetes and smoking, preoperative medicines (except that more patients with RAS inhibitors had a history of hypertension or congestive heart failure, fewer RAS inhibitor patients had chronic lung disease), in intraoperative perfusion and aortic cross-clamp time, and in postoperative complications and 30-d mortality. Multivariate logistic regression analysis demonstrated, however, that preoperative RAS inhibitors significantly and independently reduced the incidence of postoperative RF in the patients undergoing cardiac surgery compared with those not taking RAS inhibitors: 1.6% versus 7.6%, yielding an odds ratio of 0.19 (95 % CI 0.04-0.84, P = 0.029). Preoperative RAS inhibitors may have significant renoprotective effects for aging patients undergoing elective cardiac surgery. Copyright © 2011 Elsevier Inc. All rights reserved.

  15. A novel risk classification system for 30-day mortality in children undergoing surgery

    Science.gov (United States)

    Walter, Arianne I.; Jones, Tamekia L.; Huang, Eunice Y.; Davis, Robert L.

    2018-01-01

    A simple, objective and accurate way of grouping children undergoing surgery into clinically relevant risk groups is needed. The purpose of this study, is to develop and validate a preoperative risk classification system for postsurgical 30-day mortality for children undergoing a wide variety of operations. The National Surgical Quality Improvement Project-Pediatric participant use file data for calendar years 2012–2014 was analyzed to determine preoperative variables most associated with death within 30 days of operation (D30). Risk groups were created using classification tree analysis based on these preoperative variables. The resulting risk groups were validated using 2015 data, and applied to neonates and higher risk CPT codes to determine validity in high-risk subpopulations. A five-level risk classification was found to be most accurate. The preoperative need for ventilation, oxygen support, inotropic support, sepsis, the need for emergent surgery and a do not resuscitate order defined non-overlapping groups with observed rates of D30 that vary from 0.075% (Very Low Risk) to 38.6% (Very High Risk). When CPT codes where death was never observed are eliminated or when the system is applied to neonates, the groupings remained predictive of death in an ordinal manner. PMID:29351327

  16. A Reference Architecture for Network-Centric Information Systems

    National Research Council Canada - National Science Library

    Renner, Scott; Schaefer, Ronald

    2003-01-01

    This paper presents the "C2 Enterprise Reference Architecture" (C2ERA), which is a new technical concept of operations for building information systems better suited to the Network-Centric Warfare (NCW) environment...

  17. SNAP operating system reference manual

    International Nuclear Information System (INIS)

    Sabuda, J.D.; Polito, J.; Walker, J.L.; Grant, F.H. III.

    1982-03-01

    The SNAP Operating System (SOS) is a FORTRAN 77 program which provides assistance to the safeguards analyst who uses the Safeguards Automated Facility Evaluation (SAFE) and the Safeguards Network Analysis Procedure (SNAP) techniques. Features offered by SOS are a data base system for storing a library of SNAP applications, computer graphics representation of SNAP models, a computer graphics editor to develop and modify SNAP models, a SAFE-to-SNAP interface, automatic generation of SNAP input data, and a computer graphic post-processor for SNAP. The SOS Reference Manual provides detailed application information concerning SOS as well as a detailed discussion of all SOS components and their associated command input formats. SOS was developed for the US Nuclear Regulatory Commission's Office of Nuclear Regulatory Research and the US Naval Surface Weapons Center by Pritsker and Associates, Inc., under contract to Sandia National Laboratories

  18. A reference model for space data system interconnection services

    Science.gov (United States)

    Pietras, John; Theis, Gerhard

    1993-01-01

    The widespread adoption of standard packet-based data communication protocols and services for spaceflight missions provides the foundation for other standard space data handling services. These space data handling services can be defined as increasingly sophisticated processing of data or information received from lower-level services, using a layering approach made famous in the International Organization for Standardization (ISO) Open System Interconnection Reference Model (OSI-RM). The Space Data System Interconnection Reference Model (SDSI-RM) incorporates the conventions of the OSIRM to provide a framework within which a complete set of space data handling services can be defined. The use of the SDSI-RM is illustrated through its application to data handling services and protocols that have been defined by, or are under consideration by, the Consultative Committee for Space Data Systems (CCSDS).

  19. Reference clock parameters for digital communications systems applications

    Science.gov (United States)

    Kartaschoff, P.

    1981-01-01

    The basic parameters relevant to the design of network timing systems describe the random and systematic time departures of the system elements, i.e., master (or reference) clocks, transmission links, and other clocks controlled over the links. The quantitative relations between these parameters were established and illustrated by means of numerical examples based on available measured data. The examples were limited to a simple PLL control system but the analysis can eventually be applied to more sophisticated systems at the cost of increased computational effort.

  20. Hazardous Solvent Substitution Data System reference manual

    International Nuclear Information System (INIS)

    Branham-Haar, K.A.; Twitchell, K.E.

    1993-07-01

    Concern for the environment, in addition to Federal regulation, mandate the replacement of hazardous solvents with safer cleaning agents. Manufacturers are working to produce these replacement solvents. As these products are developed, potential users need to be informed of their availability. To promote the use of these new products instead of traditional solvents, the Idaho National Engineering Laboratory (INEL) has developed the Hazardous Solvent Substitution Data System (HSSDS). The HSSDS provides a comprehensive system of information on alternatives to hazardous solvents and related subjects, and it makes that information available to solvent users, industrial hygienists, and process engineers. The HSSDS uses TOPIC reg-sign, a text retrieval system produced by Verity, Inc., to allow a user to search for information on a particular subject. TOPIC reg-sign produces a listing of the retrieved documents and allows the use to examine the documents individually and to use the information contained in them. This reference manual does not replace the comprehensive TOPIC reg-sign user documentation (available from Verity, Inc.), or the HSSDS Tutorial (available from the INEL). The purpose of this reference manual is to provide enough instruction on TOPIC reg-sign so the user may begin accessing the data contained in the HSSDS

  1. Mobile User Objective Systems (MUOS) Reference Implementation Laboratory (MRIL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Mobile User Objective Systems (MUOS) Reference Implementation Laboratory (MRIL) performs verification and validation testing of various MUOS terminals. MRIL also...

  2. Reference Sources in Chemistry

    OpenAIRE

    Sthapit, Dilip Man

    1995-01-01

    Information plays an important role in the development of every field. Therefore a brief knowledge regarding information sources is necessary to function in any field. There are many information sources about scientific and technical subjects. In this context there are many reference sources in Chemistry too. Chemistry is one important part of the science which deals with the study of the composition of substances and the chemical changes that they undergo. The purpose of this report is...

  3. An analog cell to detect single event transients in voltage references

    Energy Technology Data Exchange (ETDEWEB)

    Franco, F.J., E-mail: fjfranco@fis.ucm.es [Departamento de Física Aplicada III, Facultad de Físicas, Universidad Complutense de Madrid (UCM), 28040 Madrid (Spain); Palomar, C. [Departamento de Física Aplicada III, Facultad de Físicas, Universidad Complutense de Madrid (UCM), 28040 Madrid (Spain); Izquierdo, J.G. [Centro de Láseres Ultrarrápidos, Facultad de Químicas, Universidad Complutense de Madrid (UCM), 28040 Madrid (Spain); Agapito, J.A. [Departamento de Física Aplicada III, Facultad de Físicas, Universidad Complutense de Madrid (UCM), 28040 Madrid (Spain)

    2015-01-11

    A reliable voltage reference is mandatory in mixed-signal systems. However, this family of components can undergo very long single event transients when operating in radiation environments such as space and nuclear facilities due to the impact of heavy ions. The purpose of the present paper is to demonstrate how a simple cell can be used to detect these transients. The cell was implemented with typical COTS components and its behavior was verified by SPICE simulations and in a laser facility. Different applications of the cell are explored as well.

  4. On Chinese National Continuous Operating Reference Station System of GNSS

    Directory of Open Access Journals (Sweden)

    CHEN Junyong

    2007-11-01

    Full Text Available Objective: Global navigation satellite system (GNSS Continuous Operating Reference Station (CORS System can maintain a accurate, 3D, geocentric and dynamic reference coordinate frame in the corresponding area, can provide positioning and navigation service. It can also serve for the meteorology, geodynamics, earthquake monitoring and Location Based services (LBS etc in the same area. Until now, our country can’t provide a facing National CORS System serving for every profession and trade, and the national sharing platform of CORS System resources has not been established. So this paper discusses some valuable insight how to construct the National CORS System in China. Method: Constructing goal、Service object、CORS distribution、CORS geographic、geology and communication environment and other factors, are major considerations for the Constructing the National CORS System. Moreover, constructing GNSS CORS is more specific, mainly from four aspects, namely site-selection、civil construction、security measures and equipment-selection for consideration. Outcome: The project of the Constructing Global navigation satellite system (GNSS Continuous Operating Reference Station (CORS System in china is put forward, and is discussed from goal、principle、project and other for construction. Some meaning thought how to construct the National CORS System is submitted Conclusion: The Global navigation satellite system (GNSS Continuous Operating Reference Station (CORS System in china is the lack of a unified planning and design in the national level. So far, the national CORS system serving all walks of life has not been provided, and the national sharing platform of CORS System resources has not been established The primary mission of the Global navigation satellite system (GNSS Continuous Operating Reference Station (CORS System in china is as follows: using data set of GNSS and receiving, transport, process, integration, transmit information and

  5. On the theory of transformations of coordinates for massive systems of reference

    International Nuclear Information System (INIS)

    Sadykov, B.S.

    1978-01-01

    Suggested is a new local group of coordinate transformations of reference systems connected with massive bodies, such as the Earth, the Sun and so on, which are rather inertial in the kinematic relation, but possess different gravitational fields. The effect of the gravitational field of the reference body upon the metric of the system is taken into account. For identical systems the new group transfers into the Lorentz group

  6. Reference dosimeter system of the IAEA

    International Nuclear Information System (INIS)

    Mehta, Kishor; Girzikowsky, Reinhard

    1995-01-01

    Quality assurance programmes must be in operation at radiation facilities to satisfy national and international Standards. Since dosimetry has a vital function in these QA programmes, it is imperative that the dosimetry systems in use at these facilities are well calibrated with a traceability to a Primary Standard Dosimetry Laboratory. As a service to the Member States, the International Atomic Energy Agency operates the International Dose Assurance Service (IDAS) to assist in this process. The transfer standard dosimetry system that is used for this service is based on ESR spectrometry. The paper describes the activities undertaken at the IAEA Dosimetry Laboratory to establish the QA programme for its reference dosimetry system. There are four key elements of such a programme: quality assurance manual; calibration that is traceable to a Primary Standard Dosimetry Laboratory; a clear and detailed statement of uncertainty in the dose measurement; and, periodic quality audit. (Author)

  7. Reference dosimeter system of the iaea

    Science.gov (United States)

    Mehta, Kishor; Girzikowsky, Reinhard

    1995-09-01

    Quality assurance programmes must be in operation at radiation processing facilities to satisfy national and international Standards. Since dosimetry has a vital function in these QA programmes, it is imperative that the dosimetry systems in use at these facilities are well calibrated with a traceability to a Primary Standard Dosimetry Laboratory. As a service to the Member States, the International Atomic Energy Agency operates the International Dose Assurance Service (IDAS) to assist in this process. The transfer standard dosimetry system that is used for this service is based on ESR spectrometry. The paper describes the activities undertaken at the IAEA Dosimetry Laboratory to establish the QA programme for its reference dosimetry system. There are four key elements of such a programme: quality assurance manual; calibration that is traceable to a Primary Standard Dosimetry Laboratory; a clear and detailed statement of uncertainty in the dose measurement; and, periodic quality audit.

  8. Reference dosimeter system of the IAEA

    International Nuclear Information System (INIS)

    Mehta, K.; Girzikowsky, R.

    1995-01-01

    Quality assurance programmes must be in operation at radiation processing facilities to satisfy national and international standards. Since dosimetry has a vital function in these QA programmes, it is imperative that the dosimetry systems in use at these facilities are well calibrated with a traceability to a Primary Standard Dosimetry Laboratory. As a service to the Member States, the International Atomic Energy Agency operates the International Dose Assurance Service (IDAS) to assist in this process. The transfer standard dosimetry system that is used for this service is based on ESR spectrometry. The paper describes the activities undertaken at the IAEA Dosimetry Laboratory to establish the QA programme for its reference dosimetry system. There are four key elements of such a programme: quality assurance manual; calibration that is traceable to a Primary Standard Dosimetry Laboratory; a clear and detailed statement of uncertainty in the dose measurement; and, periodic quality audit. (author)

  9. Environmental systems analysis of biogas systems-Part II: The environmental impact of replacing various reference systems

    International Nuclear Information System (INIS)

    Boerjesson, Pal; Berglund, Maria

    2007-01-01

    This paper analyses the overall environmental impact when biogas systems are introduced and replace various reference systems for energy generation, waste management and agricultural production. The analyses are based on Swedish conditions using a life-cycle perspective. The biogas systems included are based on different combinations of raw materials and final use of the biogas produced (heat, power and transportation fuel). A general conclusion is that biogas systems normally lead to environmental improvements, which in some cases are considerable. This is often due to indirect environmental benefits of changed land use and handling of organic waste products (e.g. reduced nitrogen leaching, emissions of ammonia and methane), which often exceed the direct environmental benefits achieved when fossil fuels are replaced by biogas (e.g. reduced emissions of carbon dioxide and air pollutants). Such indirect benefits are seldom considered when biogas is evaluated from an environmental point of view. The environmental impact from different biogas systems can, however, vary significantly due to factors such as the raw materials utilised, energy service provided and reference system replaced

  10. Performance evaluation of the Antares Reference Telescope System

    International Nuclear Information System (INIS)

    Parker, J.R.; Woodfin, G.L.; Viswanathan, V.K.

    1985-01-01

    The Antares Reference Telescope System is a complicated electro-optical-mechanical system whose main purpose is to enable positioning of targets used in the Antares Laser System to within 10 μm of a selected nominal position. To date, it has been used successfully to position targets ranging in size from 300 μm to 2 mm. The system consists of two electro-optical systems positioned in a nearly orthogonal manner. This ''cross telescope'' configuration facilitates accurate positioning in three planes. The results obtained so far in resolution and positioning of targets using this system are discussed. It is shown that a resolution of 200 lp/mm and a positioning precision of 25 μm can be obtained

  11. Speed Sensorless Control of PMSM using Model Reference Adaptive System and RBFN

    OpenAIRE

    Wei Gao; Zhirong Guo

    2013-01-01

    In the speed sensorless vector control system, the amended method of estimating the rotor speed about model reference adaptive system (MRAS) based on radial basis function neural network (RBFN) for PMSM sensorless vector control system was presented. Based on the PI regulator, the radial basis function neural network which is more prominent learning efficiency and performance is combined with MRAS. The reference model and the adjust model are the PMSM itself and the PMSM current, respectively...

  12. Activity Management System user reference manual. Revision 1

    International Nuclear Information System (INIS)

    Gates, T.A.; Burdick, M.B.

    1994-01-01

    The Activity Management System (AMS) was developed in response to the need for a simple-to-use, low-cost, user interface system for collecting and logging Hanford Waste Vitrification Plant Project (HWVP) activities. This system needed to run on user workstations and provide common user access to a database stored on a local network file server. Most important, users wanted a system that provided a management tool that supported their individual process for completing activities. Existing system treated the performer as a tool of the system. All AMS data is maintained in encrypted format. Users can feel confident that any activities they have entered into the database are private and that, as the originator, they retain sole control over who can see them. Once entered into the AMS database, the activities cannot be accessed by anyone other than the originator, the designated agent, or by authorized viewers who have been explicitly granted the right to look at specific activities by the originator. This user guide is intended to assist new AMS users in learning how to use the application and, after the initial learning process, will serve as an ongoing reference for experienced users in performing infrequently used functions. Online help screens provide reference to some of the key information in this manual. Additional help screens, encompassing all the applicable material in this manual, will be incorporated into future AMS revisions. A third, and most important, source of help is the AMS administrator(s). This guide describes the initial production version of AMS, which has been designated Revision 1.0

  13. MATHEMATICAL MODEL OF TRIAXIAL MULTIMODE ATTITUDE AND HEADING REFERENCE SYSTEM

    Directory of Open Access Journals (Sweden)

    Olha Sushchenko

    2017-07-01

    Full Text Available Purpose: The paper deals with the mathematical description of the gimballed attitude and heading reference systems, which can be applied in design of strategic precision navigation systems. The main goal is to created mathematical description taking into consideration the necessity to use different navigations operating modes of this class of navigation systems. To provide the high accuracy the indirect control is used when the position of the gimballed platform is controlled by signals of gyroscopic devices, which are corrected using accelerometer’s signals. Methods: To solve the given problem the methods of the classical theoretical mechanics, gyro theory, and inertial navigation are used. Results: The full mathematical model of the gimballed attitude and heading reference system is derived including descriptions of different operating modes. The mathematical models of the system Expressions for control and correction moments in the different modes are represented. The simulation results are given. Conclusions: The represented results prove efficiency of the proposed models. Developed mathematical models can be useful for design of navigation systems of the wide class of moving vehicles.

  14. Nuclear thermal rocket workshop reference system Rover/NERVA

    International Nuclear Information System (INIS)

    Borowski, S.K.

    1991-01-01

    The Rover/NERVA engine system is to be used as a reference, against which each of the other concepts presented in the workshop will be compared. The following topics are reviewed: the operational characteristics of the nuclear thermal rocket (NTR); the accomplishments of the Rover/NERVA programs; and performance characteristics of the NERVA-type systems for both Mars and lunar mission applications. Also, the issues of ground testing, NTR safety, NASA's nuclear propulsion project plans, and NTR development cost estimates are briefly discussed

  15. An implicit adaptation algorithm for a linear model reference control system

    Science.gov (United States)

    Mabius, L.; Kaufman, H.

    1975-01-01

    This paper presents a stable implicit adaptation algorithm for model reference control. The constraints for stability are found using Lyapunov's second method and do not depend on perfect model following between the system and the reference model. Methods are proposed for satisfying these constraints without estimating the parameters on which the constraints depend.

  16. Reference material systems: a sourcebook for material assessment

    Energy Technology Data Exchange (ETDEWEB)

    Bhagat, N. (ed.)

    1976-12-01

    A reference set of data related to material systems and a framework for carrying out the material technologies assessment are presented. While the bulk of renewables have been considered in this report, the nonrenewable materials dealt with here include structural materials only, such as steel, aluminum, cement and concrete, and bricks. The complete data set is supposed to include material flows, energy requirements, capital and labor inputs, and environmental effects for each process that a resource must go through to become a useful material for an end use. Although effort has been made to obtain as much information as possible, considerable gaps in data, apparent throughout this report, could not be avoided. A new material technology can be evaluated by substituting that technology for appropriate elements of the reference materials system and calculating the net change in material resource, energy, capital and labor requirements, and environmental impacts. This combination of information thus serves as a means of evaluating the potential benefits to be gained by research in various material technologies.

  17. A reference system for animal biometrics: application to the northern leopard frog

    Science.gov (United States)

    Petrovska-Delacretaz, D.; Edwards, A.; Chiasson, J.; Chollet, G.; Pilliod, D.S.

    2014-01-01

    Reference systems and public databases are available for human biometrics, but to our knowledge nothing is available for animal biometrics. This is surprising because animals are not required to give their agreement to be in a database. This paper proposes a reference system and database for the northern leopard frog (Lithobates pipiens). Both are available for reproducible experiments. Results of both open set and closed set experiments are given.

  18. Referring to IAEA system to improve Chinese standards system on nuclear and radiation safety

    International Nuclear Information System (INIS)

    Shang Zhaorong; Wang Wenhai

    2010-01-01

    Referring to the standards system of IAEA, to build and improve the Chinese standards system of nuclear and radiation safety is a long term infrastructure work and an assurance to keep sustainable development of nuclear industry and nuclear technology application in China. The paper analyses the current main problem, and gives some suggestions on developing and improving the system. (authors)

  19. Systemic scleroderma diagnosed after undergoing radiation therapy for breast cancer

    International Nuclear Information System (INIS)

    Sasaki, Tetsuo; Kakei, Masae

    1994-01-01

    A case of systemic scleroderma in which the symptoms became prominent after undergoing radiation therapy for breast cancer is reported. A 68-year-old woman, who had undergone a radical mastectomy for breast carcinoma at the age of 63 and thereafter received radiotherapy at 65, 66 and 67 years of age, visited our clinic complaining of skin sclerosis and Raynaud's phenomenon which she had noticed since the age of 65. The physical examination revealed not only postirradiation fibrosis and pigmentation, but also edematous sclerosis and the pigmentation of her extremities, as well as short frenulum of the tongue and digital pitting scars. She demonstrated serum anti-topoisomerase I antibodies, esophageal dysfunction and lung fibrosis. The histopathology of the forearm skin showed edema of the upper dermis as well as increased and homogenized collagen bundles in the middle and lower dermis. Since similar cases have been reported, it is considerable that radiation therapy may have thus worsened the lesions of scleroderma in this patient as well. (author)

  20. Testing and reference model analysis of FTTH system

    Science.gov (United States)

    Feng, Xiancheng; Cui, Wanlong; Chen, Ying

    2009-08-01

    With rapid development of Internet and broadband access network, the technologies of xDSL, FTTx+LAN , WLAN have more applications, new network service emerges in endless stream, especially the increase of network game, meeting TV, video on demand, etc. FTTH supports all present and future service with enormous bandwidth, including traditional telecommunication service, traditional data service and traditional TV service, and the future digital TV and VOD. With huge bandwidth of FTTH, it wins the final solution of broadband network, becomes the final goal of development of optical access network.. Fiber to the Home (FTTH) will be the goal of telecommunications cable broadband access. In accordance with the development trend of telecommunication services, to enhance the capacity of integrated access network, to achieve triple-play (voice, data, image), based on the existing optical Fiber to the curb (FTTC), Fiber To The Zone (FTTZ), Fiber to the Building (FTTB) user optical cable network, the optical fiber can extend to the FTTH system of end-user by using EPON technology. The article first introduced the basic components of FTTH system; and then explain the reference model and reference point for testing of the FTTH system; Finally, by testing connection diagram, the testing process, expected results, primarily analyze SNI Interface Testing, PON interface testing, Ethernet performance testing, UNI interface testing, Ethernet functional testing, PON functional testing, equipment functional testing, telephone functional testing, operational support capability testing and so on testing of FTTH system. ...

  1. The disposal of Canada's nuclear fuel waste: postclosure assessment of a reference system

    International Nuclear Information System (INIS)

    Goodwin, B.W.; McConnell, D.B.; Andres, T.H.

    1994-01-01

    The concept for disposal of Canada's nuclear fuel waste is based on a vault located deep in plutonic rock of the Canadian Shield. We document in this report a method to assess the long-term impacts of a disposal facility for nuclear fuel waste. The assessment integrates relevant information from engineering design studies, site investigations, laboratory studies, expert judgment and detailed mathematical analyses to evaluate system performance in terms of safety criteria, guidelines and standards. The method includes the use of quantitative tools such as the Systems Variability Analysis computer Code (SYVAC) to deal with parameter uncertainty and the use of reasoned arguments based on well-established scientific principles. We also document the utility of the method by describing its application to a hypothetical implementation of the concept called the reference disposal system. The reference disposal system generally conforms to the overall characteristics of the concept, except we have made some specific site and design choices so that the assessment would be more realistic. To make the reference system more representative of a real system, we have used the geological observations of the AECL's Whiteshell Research Area located near Lac du Bonnet, Manitoba, to define the characteristics of the geosphere and the groundwater flow system. This research area has been subject to more than a decade of geological and hydrological studies. The analysis of the reference disposal system provides estimates of radiological and chemical toxicity impacts on members of a critical group and estimates of possible impacts on the environment. The latter impacts include estimates of radiation dose to nonhuman organisms. Other quantitative analyses examine the use of derived constraints to improve the margin of safety, the effectiveness of engineered and natural barriers, and the sensitivity of the results to influential features, events, and processes of the reference disposal

  2. Risk of Ionizing Radiation in Women of Childbearing Age undergoing Radiofrequency Ablation

    Energy Technology Data Exchange (ETDEWEB)

    Lima, Gustavo Glotz de, E-mail: gglima.pesquisa@gmail.com; Gomes, Daniel Garcia; Gensas, Caroline Saltz; Simão, Mariana Fernandez; Rios, Matheus N.; Pires, Leonardo Martins; Kruse, Marcelo Lapa; Leiria, Tiago Luiz Luz [Instituto de Cardiologia, Fundação Universitária de Cardiologia, Porto Alegre, RS (Brazil)

    2013-11-15

    The International Commission of Radiology recommends a pregnancy screening test to all female patients of childbearing age who will undergo a radiological study. Radiation is known to be teratogenic and its effect is cumulative. The teratogenic potential starts at doses close to those used during these procedures. The prevalence of positive pregnancy tests in patients undergoing electrophysiological studies and/or catheter ablation in our midst is unknown. To evaluate the prevalence of positive pregnancy tests in female patients referred for electrophysiological study and/or radiofrequency ablation. Cross-sectional study analyzing 2,966 patients undergoing electrophysiological study and/or catheter ablation, from June 1997 to February 2013, in the Institute of Cardiology of Rio Grande do Sul. A total of 1490 procedures were performed in women, of whom 769 were of childbearing age. All patients were screened with a pregnancy test on the day before the procedure. Three patients tested positive, and were therefore unable to undergo the procedure. The prevalence observed was 3.9 cases per 1,000 women of childbearing age. Because of their safety and low cost, pregnancy screening tests are indicated for all women of childbearing age undergoing radiological studies, since the degree of ionizing radiation needed for these procedures is very close to the threshold for teratogenicity, especially in the first trimester, when the signs of pregnancy are not evident.

  3. Risk of Ionizing Radiation in Women of Childbearing Age undergoing Radiofrequency Ablation

    International Nuclear Information System (INIS)

    Lima, Gustavo Glotz de; Gomes, Daniel Garcia; Gensas, Caroline Saltz; Simão, Mariana Fernandez; Rios, Matheus N.; Pires, Leonardo Martins; Kruse, Marcelo Lapa; Leiria, Tiago Luiz Luz

    2013-01-01

    The International Commission of Radiology recommends a pregnancy screening test to all female patients of childbearing age who will undergo a radiological study. Radiation is known to be teratogenic and its effect is cumulative. The teratogenic potential starts at doses close to those used during these procedures. The prevalence of positive pregnancy tests in patients undergoing electrophysiological studies and/or catheter ablation in our midst is unknown. To evaluate the prevalence of positive pregnancy tests in female patients referred for electrophysiological study and/or radiofrequency ablation. Cross-sectional study analyzing 2,966 patients undergoing electrophysiological study and/or catheter ablation, from June 1997 to February 2013, in the Institute of Cardiology of Rio Grande do Sul. A total of 1490 procedures were performed in women, of whom 769 were of childbearing age. All patients were screened with a pregnancy test on the day before the procedure. Three patients tested positive, and were therefore unable to undergo the procedure. The prevalence observed was 3.9 cases per 1,000 women of childbearing age. Because of their safety and low cost, pregnancy screening tests are indicated for all women of childbearing age undergoing radiological studies, since the degree of ionizing radiation needed for these procedures is very close to the threshold for teratogenicity, especially in the first trimester, when the signs of pregnancy are not evident

  4. RF Phase Reference Distribution System for the TESLA Technology Based Projects

    CERN Document Server

    Czuba, K; Romaniuk, R S

    2013-01-01

    Since many decades physicists have been building particle accelerators and usually new projects became more advanced, more complicated and larger than predecessors. The importance and complexity of the phase reference distribution systems used in these accelerators have grown significantly during recent years. Amongst the most advanced of currently developed accelerators are projects based on the TESLA technology. These projects require synchronization of many RF devices with accuracy reaching femtosecond levels over kilometre distances. Design of a phase reference distribution system fulfilling such requirements is a challenging scientific task. There are many interdisciplinary problems which must be solved during the system design. Many, usually negligible issues, may became very important in such system. Furthermore, the design of a distribution system on a scale required for the TESLA technology based projects is a new challenge and there is almost no literature sufficiently covering this subject. This th...

  5. Accuracy of Referring Provider and Endoscopist Impressions of Colonoscopy Indication.

    Science.gov (United States)

    Naveed, Mariam; Clary, Meredith; Ahn, Chul; Kubiliun, Nisa; Agrawal, Deepak; Cryer, Byron; Murphy, Caitlin; Singal, Amit G

    2017-07-01

    Background: Referring provider and endoscopist impressions of colonoscopy indication are used for clinical care, reimbursement, and quality reporting decisions; however, the accuracy of these impressions is unknown. This study assessed the sensitivity, specificity, positive and negative predictive value, and overall accuracy of methods to classify colonoscopy indication, including referring provider impression, endoscopist impression, and administrative algorithm compared with gold standard chart review. Methods: We randomly sampled 400 patients undergoing a colonoscopy at a Veterans Affairs health system between January 2010 and December 2010. Referring provider and endoscopist impressions of colonoscopy indication were compared with gold-standard chart review. Indications were classified into 4 mutually exclusive categories: diagnostic, surveillance, high-risk screening, or average-risk screening. Results: Of 400 colonoscopies, 26% were performed for average-risk screening, 7% for high-risk screening, 26% for surveillance, and 41% for diagnostic indications. Accuracy of referring provider and endoscopist impressions of colonoscopy indication were 87% and 84%, respectively, which were significantly higher than that of the administrative algorithm (45%; P 90%) for determining screening (vs nonscreening) indication, but specificity of the administrative algorithm was lower (40.3%) compared with referring provider (93.7%) and endoscopist (84.0%) impressions. Accuracy of endoscopist, but not referring provider, impression was lower in patients with a family history of colon cancer than in those without (65% vs 84%; P =.001). Conclusions: Referring provider and endoscopist impressions of colonoscopy indication are both accurate and may be useful data to incorporate into algorithms classifying colonoscopy indication. Copyright © 2017 by the National Comprehensive Cancer Network.

  6. The Necessity of Real-Time: Fact and Fiction in Digital Reference Systems.

    Science.gov (United States)

    Lankes, R. David; Shostack, Pauline

    2002-01-01

    Discussion of digital reference services and the use of real-time versus asynchronous services such as email focuses on data from the AskERIC digital reference service to demonstrate that asynchronous services are not only useful but may have greater utility than real-time systems. (Author/LRW)

  7. Digital Receiver Design for Transmitted Reference Ultra-Wideband Systems

    NARCIS (Netherlands)

    Wang, Y.; Leus, G.; Van der Veen, A.J.

    2009-01-01

    A complete detection, channel estimation, synchronization, and equalization scheme for a transmitted reference (TR) ultra-wideband (UWB) system is proposed in this paper. The scheme is based on a data model which admits a moderate data rate and takes both the interframe interference (IFI) and the

  8. Hepatic Steatosis in Morbidly Obese Patients Undergoing Gastric Bypass Surgery: Assessment With Open-System 1H-MR Spectroscopy

    NARCIS (Netherlands)

    van Werven, Jochem R.; Schreuder, Tim C. M. A.; Aarts, Edo O.; Nederveen, Aart J.; Meijer, Jos W. R.; Berends, Frits J.; Janssen, Ignace M. C.; Mulder, Chris J.; Jansen, Peter L. M.; Stoker, Jaap

    2011-01-01

    The purpose of this study was to assess, with histopathologic control, the use of open-system 1-T (1)H MR spectroscopy for the evaluation of hepatic steatosis in morbidly obese patients undergoing gastric bypass surgery. Patients underwent (1)H MR spectroscopy (MRS) for the assessment of steatosis

  9. Climate mitigation comparison of woody biomass systems with the inclusion of land-use in the reference fossil system

    International Nuclear Information System (INIS)

    Haus, S.; Gustavsson, L.; Sathre, R.

    2014-01-01

    While issues of land-use have been considered in many direct analyses of biomass systems, little attention has heretofore been paid to land-use in reference fossil systems. Here we address this limitation by comparing forest biomass systems to reference fossil systems with explicit consideration of land-use in both systems. We estimate and compare the time profiles of greenhouse gas (GHG) emission and cumulative radiative forcing (CRF) of woody biomass systems and reference fossil systems. A life cycle perspective is used that includes all significant elements of both systems, including GHG emissions along the full material and energy chains. We consider the growth dynamics of forests under different management regimes, as well as energy and material substitution effects of harvested biomass. We determine the annual net emissions of CO 2 , N 2 O and CH 4 for each system over a 240-year period, and then calculate time profiles of CRF as a proxy measurement of climate change impact. The results show greatest potential for climate change mitigation when intensive forest management is applied in the woody biomass system. This methodological framework provides a tool to help determine optimal strategies for managing forests so as to minimize climate change impacts. The inclusion of land-use in the reference system improves the accuracy of quantitative projections of climate benefits of biomass-based systems. - Highlights: • We analyze the dynamics of GHG emissions from woody biomass and fossil systems. • With a life cycle perspective, we account for forest land-use in both systems. • Replacing more carbon intensive fossil fuels gives greater climate benefit. • Increasing the intensity of forest management gives greater climate benefit. • Methodological choices in defining temporal system boundaries are important

  10. Systemic scleroderma diagnosed after undergoing radiation therapy for breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Sasaki, Tetsuo; Kakei, Masae (Yokohama City Univ. (Japan). Faculty of Medicine)

    1994-10-01

    A case of systemic scleroderma in which the symptoms became prominent after undergoing radiation therapy for breast cancer is reported. A 68-year-old woman, who had undergone a radical mastectomy for breast carcinoma at the age of 63 and thereafter received radiotherapy at 65, 66 and 67 years of age, visited our clinic complaining of skin sclerosis and Raynaud's phenomenon which she had noticed since the age of 65. The physical examination revealed not only postirradiation fibrosis and pigmentation, but also edematous sclerosis and the pigmentation of her extremities, as well as short frenulum of the tongue and digital pitting scars. She demonstrated serum anti-topoisomerase I antibodies, esophageal dysfunction and lung fibrosis. The histopathology of the forearm skin showed edema of the upper dermis as well as increased and homogenized collagen bundles in the middle and lower dermis. Since similar cases have been reported, it is considerable that radiation therapy may have thus worsened the lesions of scleroderma in this patient as well. (author).

  11. Nouns referring to tools and natural objects differentially modulate the motor system.

    Science.gov (United States)

    Gough, Patricia M; Riggio, Lucia; Chersi, Fabian; Sato, Marc; Fogassi, Leonardo; Buccino, Giovanni

    2012-01-01

    While increasing evidence points to a critical role for the motor system in language processing, the focus of previous work has been on the linguistic category of verbs. Here we tested whether nouns are effective in modulating the motor system and further whether different kinds of nouns - those referring to artifacts or natural items, and items that are graspable or ungraspable - would differentially modulate the system. A Transcranial Magnetic Stimulation (TMS) study was carried out to compare modulation of the motor system when subjects read nouns referring to objects which are Artificial or Natural and which are Graspable or Ungraspable. TMS was applied to the primary motor cortex representation of the first dorsal interosseous (FDI) muscle of the right hand at 150 ms after noun presentation. Analyses of Motor Evoked Potentials (MEPs) revealed that across the duration of the task, nouns referring to graspable artifacts (tools) were associated with significantly greater MEP areas. Analyses of the initial presentation of items revealed a main effect of graspability. The findings are in line with an embodied view of nouns, with MEP measures modulated according to whether nouns referred to natural objects or artifacts (tools), confirming tools as a special class of items in motor terms. Additionally our data support a difference for graspable versus non graspable objects, an effect which for natural objects is restricted to initial presentation of items. Copyright © 2011 Elsevier Ltd. All rights reserved.

  12. The Asymptotic Behavior of Particle Size Distribution Undergoing Brownian Coagulation Based on the Spline-Based Method and TEMOM Model

    Directory of Open Access Journals (Sweden)

    Qing He

    2018-01-01

    Full Text Available In this paper, the particle size distribution is reconstructed using finite moments based on a converted spline-based method, in which the number of linear system of equations to be solved reduced from 4m × 4m to (m + 3 × (m + 3 for (m + 1 nodes by using cubic spline compared to the original method. The results are verified by comparing with the reference firstly. Then coupling with the Taylor-series expansion moment method, the evolution of particle size distribution undergoing Brownian coagulation and its asymptotic behavior are investigated.

  13. Decision support systems in nuclear emergencies: harmonizing domestic and reference tools

    International Nuclear Information System (INIS)

    Vamanu, D.; Mateescu, Gh.; Berinde, A.; Slavnicu, D.; Acasandrei, V.; Slavnicu, E.

    2001-01-01

    The paper addresses the issue of securing the compatibility and inter-operability of computer packages designed to perform as decision support tools in the management of radiological emergencies, over the transition times towards the implementation and uniform acceptance and uniform acceptance of internationally-shared reference tools such as the European Union's RODOS (Real Time On-Line Decision Support System for Off-Site Nuclear Emergencies in Europe). One submits that a harmonization between the currently operational, domestic, and the reference tool can be contemplated, based on extensive code comparison and benchmarking. A case in point is presented, paralleling selected RODOS applications on simulated abnormal nuclear events, and the concurrent application of a resident software package, NOTEPAD, developed to emulate RODOS-wise function at IFIH-HH Bucharest. The reproducible similarity may make domestic decision support system (DSS) facilities useful as both practical tools and factors promoting the emergency preparedness awareness, during the interim time laps till the full development and deployment of RODOS as a reference DSS in Europe. (authors)

  14. The MADE reference information model for interoperable pervasive telemedicine systems

    NARCIS (Netherlands)

    Fung, L.S.N.; Jones, Valerie M.; Hermens, Hermanus J.

    2017-01-01

    Objectives: The main objective is to develop and validate a reference information model (RIM) to support semantic interoperability of pervasive telemedicine systems. The RIM is one component within a larger, computer-interpretable "MADE language" developed by the authors in the context of the

  15. Camera Calibration of Stereo Photogrammetric System with One-Dimensional Optical Reference Bar

    International Nuclear Information System (INIS)

    Xu, Q Y; Ye, D; Che, R S; Qi, X; Huang, Y

    2006-01-01

    To carry out the precise measurement of large-scale complex workpieces, accurately calibration of the stereo photogrammetric system has becoming more and more important. This paper proposed a flexible and reliable camera calibration of stereo photogrammetric system based on quaternion with one-dimensional optical reference bar, which has three small collinear infrared LED marks and the lengths between these marks have been precisely calibration. By moving the optical reference bar at a number of locations/orientations over the measurement volume, we calibrate the stereo photogrammetric systems with the geometric constraint of the optical reference bar. The extrinsic parameters calibration process consists of linear parameters estimation based on quaternion and nonlinear refinement based on the maximum likelihood criterion. Firstly, we linear estimate the extrinsic parameters of the stereo photogrameetric systems based on quaternion. Then with the quaternion results as the initial values, we refine the extrinsic parameters through maximum likelihood criterion with the Levenberg-Marquardt Algorithm. In the calibration process, we can automatically control the light intensity and optimize the exposure time to get uniform intensity profile of the image points at different distance and obtain higher S/N ratio. The experiment result proves that the calibration method proposed is flexible, valid and obtains good results in the application

  16. Study on the System Requirements and Structures of Mailbox Declaration System for Reference Pyroprocessing Facility in the ROK

    International Nuclear Information System (INIS)

    Jeon, Jong Kyu

    2011-01-01

    The mailbox declaration system applied for the implementation of Safeguards at the Reference Pyroprocessing Facility (REPF) plays important role to support the declared information provided from Near-Real Time Accountancy (NRTA) and provides reference data to confirm the measurement results generated from the Unattended Monitoring System (UMS) for the purposes of verification and real-time monitoring of the movements and changes of nuclear materials (NM) at the processes in the REPF. In order to install and operate the mailbox declaration system at the REPF, this study focused on the operation, security, transmission of confidential information, procedure for transmission of mailbox declaration system as system requirements, and structure of mailbox declaration system to review the declared information through the mailbox by the national authority and to transmit the revised information to the IAEA

  17. LibraryH3lp: A New Flexible Chat Reference System

    Directory of Open Access Journals (Sweden)

    Pam Sessoms

    2008-09-01

    Full Text Available LibraryH3lp is an integrated IM and web chat system designed specifically for Virtual Reference services in libraries. The software was designed for, and is currently used by, a night-time chat reference collaboraton between several large academic libraries. LibraryH3lp is designed for the workflow of chat reference, supporting multiple simultaneous operators and routing to queues of operators in a particular service area. It also supports web page embeddable chat 'widgets', as well as simultaneous gateways to multiple IM protocols. This article discusses the motivation for the development of the software, and provides an overview of LibraryH3lp's features and technical architecture. Parts of LibraryH3lp are available as open source. The complete application is available as a low-cost hosted service, and will eventually be available to be licensed for local hosting.

  18. Performance Guaranteed Inertia Emulation forDiesel-Wind System Feed Microgrid via ModelReference Control

    Energy Technology Data Exchange (ETDEWEB)

    Melin, Alexander M. [ORNL; Zhang, Yichen [University of Tennessee, Knoxville (UTK), Department of Electrical Engineering and Computer Science; Djouadi, Seddik [University of Tennessee, Knoxville (UTK), Department of Electrical Engineering and Computer Science; Olama, Mohammed M. [ORNL

    2017-04-01

    In this paper, a model reference control based inertia emulation strategy is proposed. Desired inertia can be precisely emulated through this control strategy so that guaranteed performance is ensured. A typical frequency response model with parametrical inertia is set to be the reference model. A measurement at a specific location delivers the information of disturbance acting on the diesel-wind system to the referencemodel. The objective is for the speed of the diesel-wind system to track the reference model. Since active power variation is dominantly governed by mechanical dynamics and modes, only mechanical dynamics and states, i.e., a swing-engine-governor system plus a reduced-order wind turbine generator, are involved in the feedback control design. The controller is implemented in a three-phase diesel-wind system feed microgrid. The results show exact synthetic inertia is emulated, leading to guaranteed performance and safety bounds.

  19. Water Quality in Small Community Distribution Systems. A Reference Guide for Operators

    Science.gov (United States)

    The U.S. Environmental Protection Agency (EPA) has developed this reference guide to assist the operators and managers of small- and medium-sized public water systems. This compilation provides a comprehensive picture of the impact of the water distribution system network on dist...

  20. EUPOS - Satellite multifunctional system of reference stations in Central and Eastern Europe

    Science.gov (United States)

    Sledzinski, J.

    2003-04-01

    The European project EUPOS (European Position Determination System) of establishment of a system of multifunctional satellite reference stations in Central and Eastern Europe is described in the paper. Fifteen countries intend to participate in the project: Bulgaria, Croatia, Czech Republic, Estonia, Germany, Hungary, Latvia, Lithuania, Macedonia, Poland, Romania, Russia, Serbia, Slovak Republic and Slovenia. One common project will be prepared for all countries, however it will include the existing or developed infrastructure in particular countries. The experiences of establishing and operating of the German network SAPOS as well as experiences gained by other countries will be used. The European network of stations will be compatible with the system SAPOS and future European system Galileo. The network of reference stations will provide signal for both positioning of the geodetic control points and for land, air and marine navigation. Several levels of positioning accuracy will be delivered.

  1. Development of reference problems for neutron capture therapy treatment planning systems

    International Nuclear Information System (INIS)

    Albritton, J.R.; Kiger, W.S. III

    2006-01-01

    Currently, 5 different treatment planning systems (TPSs) are or have been used in clinical trials of Neutron Capture Therapy (NCT): MacNCTPlan, NCTPlan, BNCT Rtpe, SERA, and JCDS. This paper describes work performed to comprehensively test and compare 4 of these NCT treatment planning systems in order to facilitate the pooling of patient data from the different clinical sites for analysis of the clinical results as well as to provide an important quality assurance tool for existing and future TPSs. Two different phantoms were used to evaluate the planning systems: the modified Snyder head phantom and a large water-filled box, similar to that used in the International Dosimetry Exchange for NCT. The comparison of the resulting dose profile, isodose contours, and dose volume histograms to reference calculations performed with the Monte Carlo radiation transport code MCNP5 yielded many interesting differences. Each of the planning systems deviated from the reference calculations, with the newer systems (i.e., SERA and NCTPlan) most often yielding better agreement than their predecessors (i.e., BNCT Rtpe and MacNCTPlan). The combination of simple phantoms and sources with more complicated and realistic planning conditions has produced a well-rounded and useful suite of test problems for NCT treatment planning system analysis. (author)

  2. Application Research of Horn Array Multi-Beam Antenna in Reference Source System for Satellite Interference Location

    Science.gov (United States)

    Zhou, Ping; Lin, Hui; Zhang, Qi

    2018-01-01

    The reference source system is a key factor to ensure the successful location of the satellite interference source. Currently, the traditional system used a mechanical rotating antenna which leaded to the disadvantages of slow rotation and high failure-rate, which seriously restricted the system’s positioning-timeliness and became its obvious weaknesses. In this paper, a multi-beam antenna scheme based on the horn array was proposed as a reference source for the satellite interference location, which was used as an alternative to the traditional reference source antenna. The new scheme has designed a small circularly polarized horn antenna as an element and proposed a multi-beamforming algorithm based on planar array. Moreover, the simulation analysis of horn antenna pattern, multi-beam forming algorithm and simulated satellite link cross-ambiguity calculation have been carried out respectively. Finally, cross-ambiguity calculation of the traditional reference source system has also been tested. The comparison between the results of computer simulation and the actual test results shows that the scheme is scientific and feasible, obviously superior to the traditional reference source system.

  3. Fluorescence tracers as a reference for pesticide transport in wetland systems

    Science.gov (United States)

    Lange, Jens; Passeport, Elodie; Tournebize, Julien

    2010-05-01

    Two different fluorescent tracers, Uranine (UR) and Sulforhodamine (SRB), were injected as a pulse into surface flow wetlands. Tracer breakthrough curves were used to document hydraulic efficiencies, peak attenuation and retention capacities of completely different wetland systems. The tracers were used as a reference to mimic photolytic decay (UR) and sorption (SRB) of contaminants, since a real herbicide (Isoproturon, IPU) was injected in parallel to UR and SRB. Analysis costs limited IPU sampling frequency and single samples deviated from the tracer breakthrough curves. Still, a parallel behavior of IPU and SRB could be observed in totally different wetland systems, including underground passage through drainage lines. Similar recovery rates for IPU and SRB confirmed this observation. Hence, SRB was found to be an appropriate reference tracer to mimic the behavior of mobile pesticides (low KOC, without degradation) in wetland systems and the obtained wetland characteristics for SRB may serve as an indication for contaminant retention. Owing to the properties of IPU, the obtained results should be treated as worst case scenarios for highly mobile pesticides. A comparison of six different wetland types suggested that non-steady wetland systems with large variation in water level may temporally store relatively large amounts of tracers (contaminants), partly in areas that are not continuously saturated. This may lead to an efficient attenuation of peak concentrations. However, when large parts of these systems are flushed by natural storm events, tracers (contaminants) may be re-mobilized. In steady systems vegetation density and water depth were found to be the most important factors for tracer/contaminant retention. Illustrated by SRB, sorption on sediments and vegetation was a quick, almost instantaneous process which lead to considerable tracer losses even at high flow velocities and short contact times. Shallow systems with dense vegetation appeared to be the

  4. Four Reference Models for Transparency Requirements in Information Systems

    OpenAIRE

    Hosseini, Mahmoud; Shahri, Alimohammad; Phalp, Keith T.; Ali, Ra

    2017-01-01

    Transparency is a key emerging requirement in modern businesses and their information systems. Transparency refers to the information which flows amongst stakeholders for the purpose of informed decision-making and taking the right action. Transparency is generally associated with positive connotations such as trust and accountability. However, it has been shown that it could have adverse effects such as information overload and affecting decisions objectiveness. This calls for systematic app...

  5. G-autonomy of EEG recordings of psychotic patients undergoing the primitive expression form of dance therapy

    Science.gov (United States)

    Ventouras, E.-C.; Lardi, I.; Dimitriou, S.; Margariti, A.; Chondraki, P.; Kalatzis, I.; Economou, N.-T.; Tsekou, H.; Paparrigopoulos, T.; Ktonas, P. Y.

    2015-09-01

    Primitive expression (PE) is a form of dance therapy (DT) that involves an interaction of ethologically and socially based forms which are supplied for re-enactment. Brain connectivity has been measured in electroencephalographic (EEG) data of patients with schizophrenia undergoing PE DT, using the correlation coefficient and mutual information. These parameters do not measure the existence or absence of directionality in the connectivity. The present study investigates the use of the G-autonomy measure of EEG electrode voltages of the same group of schizophrenic patients. G-autonomy is a measure of the “autonomy” of a system. It indicates the degree by which prediction of the system's future evolution is enhanced by taking into account its own past states, in comparison to predictions based on past states of a set of external variables. In the present research, “own” past states refer to voltage values in the time series recorded at a specific electrode and “external” variables refer to the voltage values recorded at other electrodes. Indication is provided for an acute effect of early-stage PE DT expressed by the augmentation of G-autonomy in the delta rhythm and an acute effect of late- stage PE DT expressed by the reduction of G-autonomy in the theta and alpha rhythms.

  6. Psychological evaluation of patients undergoing MR imaging: analysis, proposals for improvement and place of open magnet systems

    International Nuclear Information System (INIS)

    Tillier, Ph.; Leclet, H.; Laplanche, T.; Madoux, M.; Picoult, C.; Delvalle, A.; Delforge, P.M.; Malgouyres, A.

    1997-01-01

    Many patients report anxiety during MR imaging. Anxiety is due to immobility, coil noise, high temperature, duration of the examination and shape of the system. On basis of a prospective series of 250 patients undergoing MR studies, we have analysed mechanisms and reasons of anxiety. Psychological strategies are useful to reduce anxiety and improve patients' cooperation and relaxation. The easiest and most effective way is to inform the distressed patient. Information about the MRI examination must be clear and simple. Open field magnets improve comfort and global conditions of the examination realisation. Psychological consequences are less important. Open field MR systems reduce claustrophobia induced by MR imaging. (author)

  7. The Relationship Between Intracranial Pressure and Age-Chasing Age-Related Reference Values

    DEFF Research Database (Denmark)

    Pedersen, Sarah Hornshøj; Lilja-Cyron, Alexander; Andresen, Morten

    2018-01-01

    Background: No true reference values for intracranial pressure (ICP) in humans exist; current values are estimated from measurements in adults who undergo treatment in order to correct ICP. We report ICP values in a "pseudonormal" group of children and adults to examine if age affects ICP. Method...

  8. Development of Information System for Patients with Cleft Lip and Palate undergoing Operation.

    Science.gov (United States)

    Augsornwan, Darawan; Pattangtanang, Pantamanas; Surakunprapha, Palakorn

    2015-08-01

    Srinagarind Hospital has 150-200 patients with cleft lip and palate each year. When patients are admitted to hospital for surgery patients and family feel they are in a crisis of life, they feel fear anxiety and need to know about how to take care of wound, they worry if patient will feel pain, how to feed patients and many things about patients. Information is very important for patients/family to prevent complications and help their decision process, decrease parents stress and encourage better co-operation. To develop information system for patients with cleft lip-palate undergoing operation. This is an action research divided into 3 phases. Phase 1 Situation review: in this phase we interview, nursing care observation, and review nursing documents about the information giving. Phase 2 Develop information system: focus groups, for discussion about what nurses can do to develop the system to give information to patients/parents. Phase 3 evaluation: by interviewing 61 parents using the structure questionnaire. 100 percent of patients/parents received information but some items were not received. Patients/parents satisfaction was 94.9 percent, no complications. The information system development provides optimal care for patients and family with cleft lip and palate, but needs to improve some techniques or tools to give more information and evaluate further the nursing outcome after.

  9. Semiclassical neutral atom as a reference system in density functional theory.

    Science.gov (United States)

    Constantin, Lucian A; Fabiano, E; Laricchia, S; Della Sala, F

    2011-05-06

    We use the asymptotic expansions of the semiclassical neutral atom as a reference system in density functional theory to construct accurate generalized gradient approximations (GGAs) for the exchange-correlation and kinetic energies without any empiricism. These asymptotic functionals are among the most accurate GGAs for molecular systems, perform well for solid state, and overcome current GGA state of the art in frozen density embedding calculations. Our results also provide evidence for the conjointness conjecture between exchange and kinetic energies of atomic systems.

  10. Changing quantum reference frames

    OpenAIRE

    Palmer, Matthew C.; Girelli, Florian; Bartlett, Stephen D.

    2013-01-01

    We consider the process of changing reference frames in the case where the reference frames are quantum systems. We find that, as part of this process, decoherence is necessarily induced on any quantum system described relative to these frames. We explore this process with examples involving reference frames for phase and orientation. Quantifying the effect of changing quantum reference frames serves as a first step in developing a relativity principle for theories in which all objects includ...

  11. A STUDY ON DETERMINING THE REFERENCE SPREADING SEQUENCES FOR A DS/CDMACOMMUNICATION SYSTEM

    Directory of Open Access Journals (Sweden)

    Cebrail ÇİFTLİKLİ

    2002-02-01

    Full Text Available In a direct sequence/code division multiple access (DS/CDMA system, the role of the spreading sequences (codes is crucial since the multiple access interference (MAI is the main performance limitation. In this study, we propose an accurate criterion which enables the determination of the reference spreading codes which yield lower bit error rates (BER's in a given code set for a DS/CDMA system using despreading sequences weighted by stepping chip waveforms. The numerical results show that the spreading codes determined by the proposed criterion are the most suitable codes for using as references.

  12. User satisfaction with referrals at a collaborative virtual reference service Virtual reference services, Reference services, Referrals, User satisfaction

    Directory of Open Access Journals (Sweden)

    Nahyun Kwon

    2006-01-01

    Full Text Available Introduction. This study investigated unmonitored referrals in a nationwide, collaborative chat reference service. Specifically, it examined the extent to which questions are referred, the types of questions that are more likely to be referred than others, and the level of user satisfaction with the referrals in the collaborative chat reference service. Method. The data analysed for this study were 420 chat reference transaction transcripts along with corresponding online survey questionnaires submitted by the service users. Both sets of data were collected from an electronic archive of a southeastern state public library system that has participated in 24/7 Reference of the Metropolitan Cooperative Library System (MCLS. Results. Referrals in the collaborative chat reference service comprised approximately 30% of the total transactions. Circulation-related questions were the most often referred among all question types, possibly because of the inability of 'outside' librarians to access patron accounts. Most importantly, user satisfaction with referrals was found to be significantly lower than that of completed answers. Conclusion. The findings of this study addressed the importance of distinguishing two types of referrals: the expert research referrals conducive to collaborative virtual reference services; and the re-directional local referrals that increase unnecessary question traffic, thereby being detrimental to effective use of collaborative reference. Continuing efforts to conceptualize referrals in multiple dimensions are anticipated to fully grasp complex phenomena underlying referrals.

  13. A reference dosimetric system for dose interval of radiotherapy based on alanine/RPE

    International Nuclear Information System (INIS)

    Rodrigues Junior, Orlando; Galante, Ocimar L.; Campos, Leticia L.

    2001-01-01

    This work describes the development of a reference dosimetric system based on alanine/EPR for radiotherapy dose levels. Currently the IPEN is concluding a similar system for the dose range used for irradiation of products, 10-10 5 Gy. The objective of this work is to present the efforts towards to improve the measure accuracy for doses in the range between 1-10 Gy. This system could be used as reference by radiotherapy services, as much in the quality control of the equipment, as for routine accompaniment of more complex handling where the total doses can reach some grays. The system uses alanine as detector and electronic paramagnetic resonance - EPR as measure technique. To reach accuracy better than 5% mathematical studies on the best optimization of the EPR spectrometer parameters and methods for the handling of the EPR sign are discussed. (author)

  14. Design and implementation of predictive filtering system for current reference generation of active power filter

    Energy Technology Data Exchange (ETDEWEB)

    Kilic, Tomislav; Milun, Stanko; Petrovic, Goran [FESB University of Split, Faculty of Electrical Engineering, Machine Engineering and Naval Architecture, R. Boskovica bb, 21000, Split (Croatia)

    2007-02-15

    The shunt active power filters are used to attenuate the harmonic currents in power systems by injecting equal but opposite compensating currents. Successful control of the active filters requires an accurate current reference. In this paper the current reference determination based on predictive filtering structure is presented. Current reference was obtained by taking the difference of load current and its fundamental harmonic. For fundamental harmonic determination with no time delay a combination of digital predictive filter and low pass filter is used. The proposed method was implemented on a laboratory prototype of a three-phase active power filter. The algorithm for current reference determination was adapted and implemented on DSP controller. Simulation and experimental results show that the active power filter with implemented predictive filtering structure gives satisfactory performance in power system harmonic attenuation. (author)

  15. A reference model for model-based design of critical infrastructure protection systems

    Science.gov (United States)

    Shin, Young Don; Park, Cheol Young; Lee, Jae-Chon

    2015-05-01

    Today's war field environment is getting versatile as the activities of unconventional wars such as terrorist attacks and cyber-attacks have noticeably increased lately. The damage caused by such unconventional wars has also turned out to be serious particularly if targets are critical infrastructures that are constructed in support of banking and finance, transportation, power, information and communication, government, and so on. The critical infrastructures are usually interconnected to each other and thus are very vulnerable to attack. As such, to ensure the security of critical infrastructures is very important and thus the concept of critical infrastructure protection (CIP) has come. The program to realize the CIP at national level becomes the form of statute in each country. On the other hand, it is also needed to protect each individual critical infrastructure. The objective of this paper is to study on an effort to do so, which can be called the CIP system (CIPS). There could be a variety of ways to design CIPS's. Instead of considering the design of each individual CIPS, a reference model-based approach is taken in this paper. The reference model represents the design of all the CIPS's that have many design elements in common. In addition, the development of the reference model is also carried out using a variety of model diagrams. The modeling language used therein is the systems modeling language (SysML), which was developed and is managed by Object Management Group (OMG) and a de facto standard. Using SysML, the structure and operational concept of the reference model are designed to fulfil the goal of CIPS's, resulting in the block definition and activity diagrams. As a case study, the operational scenario of the nuclear power plant while being attacked by terrorists is studied using the reference model. The effectiveness of the results is also analyzed using multiple analysis models. It is thus expected that the approach taken here has some merits

  16. High-density fluid-perturbation theory based on an inverse 12th-power hard-sphere reference system

    International Nuclear Information System (INIS)

    Ross, M.

    1979-01-01

    A variational theory is developed that is accurate at normal liquid densities and densities up to 4 times that of the argon triple point. This theory uses the inverse 12th-power potential as a reference system. The properties of this reference system are expressed in terms of hard-sphere packing fractions by using a modified form of hard-space variational theory. As a result of this ''bootstrapping,'' a variational procedure may be followed that employs the inverse 12th-power system as a reference but uses the hard-sphere packing fraction as the scaling parameter with which to minimize the Helmholtz free energy

  17. Inaccuracies when mixing coordinate reference frameworks in a system of systems simulation

    CSIR Research Space (South Africa)

    Duvenhage, B

    2007-09-01

    Full Text Available commonly used are flat and spherical earth. Another well known ERM is the World Geodetic System from 1984 (WGS 84). For the purposes of this paper the authors however focus on the simpler flat and spherical earth models with example coordinate... words, the equatorial and pole to pole diameters of the earth, as modelled in this ERM, are equal. This paper will use the term ‘real world’ ERMs to refer to spherical, WGS 84 and better ERM approximations. A. The Earth-Centred, Earth...

  18. Functional representation for the grand partition function of a multicomponent system of charged particles: Correlation functions of the reference system

    Directory of Open Access Journals (Sweden)

    O.V.Patsahan

    2006-01-01

    Full Text Available Based on the method of collective variables (CV with a reference system, the exact expression for the functional of the grand partition function of a m-component ionic model with charge and size asymmetry is found. Particular attention is paid to the n-th particle correlation functions of the reference system which is presented as a m-component system of "colour" hard spheres of the same diameter. A two-component model is considered in more detail. In this case the recurrence formulas for the correlation functions are found. A general case of a m-component inhomogeneous system of the "colour" hard spheres is also analysed.

  19. Moving to a Modernized Height Reference System in Canada: Rationale, Status and Plans

    Science.gov (United States)

    Veronneau, M.; Huang, J.

    2007-05-01

    A modern society depends on a common coordinate reference system through which geospatial information can be interrelated and exploited reliably. For height measurements this requires the ability to measure mean sea level elevations easily, accurately, and at the lowest possible cost. The current national reference system for elevations, the Canadian Geodetic Vertical Datum of 1928 (CGVD28), offers only partial geographic coverage of the Canadian territory and is affected by inaccuracies that are becoming more apparent as users move to space- based technologies such as GPS. Furthermore, the maintenance and expansion of the national vertical network using spirit-levelling, a costly, time consuming and labour intensive proposition, has only been minimally funded over the past decade. It is now generally accepted that the most sustainable alternative for the realization of a national vertical datum is a gravimetric geoid model. This approach defines the datum in relation to an ellipsoid, making it compatible with space-based technologies for positioning. While simplifying access to heights above mean sea level all across the Canadian territory, this approach imposes additional demands on the quality of the geoid model. These are being met by recent and upcoming space gravimetry missions that have and will be measuring the Earth`s gravity field with increasing and unprecedented accuracy. To maintain compatibility with the CGVD28 datum materialized at benchmarks, the current first-order levelling can be readjusted by constraining geoid heights at selected stations of the Canadian Base Network. The new reference would change CGVD28 heights of benchmarks by up to 1 m across Canada. However, local height differences between benchmarks would maintain a relative precision of a few cm or better. CGVD28 will co-exist with the new height reference as long as it will be required, but it will undoubtedly disappear as benchmarks are destroyed over time. The adoption of GNSS

  20. Factors which influence the cardiac surgeon's decision not to operate on patients referred for consideration of surgery

    Directory of Open Access Journals (Sweden)

    Sivaprakasam Rajesh

    2008-02-01

    Full Text Available Abstract Background The aim of this study was to document what proportion of patients referred for consideration of cardiac surgery are turned down, the reasons given for not operating and also to evaluate what happens to those patients who do not undergo surgery. Methods 382 elective patients referred for consideration of cardiac surgery to one of six consultant cardiac surgeons at Wythenshawe Hospital during a one year period from were included in the study. Data for those patients who underwent an operation were collected prospectively in a cardiac surgery database. The case notes of those patients who did not undergo an operation were reviewed to establish reasons given by surgeons for not operating. Patients were followed up to determine vital status at the end of the study period. Results 333 (87.2% patients underwent an operation and 49 (12.8% did not. 68% of patients turned down were thought to be too high-risk. 14% of patients did not fulfill symptomatic or prognostic criteria for surgery and in 8% of patients coronary artery surgery was thought ineffective due to poor distal vessels. 6% of patients declined an operation and 4% were thought to be more suitable for coronary angioplasty. Patients turned down for surgery had more renal dysfunction (p = 0.017, respiratory disease (p Conclusion 12.8% of patients referred for consideration of cardiac surgery did not undergo an operation. Two thirds of patients not accepted for surgery were thought too high risk. Those patients who did not undergo an operation had a significantly worse mortality.

  1. Phase modulated high density collinear holographic data storage system with phase-retrieval reference beam locking and orthogonal reference encoding.

    Science.gov (United States)

    Liu, Jinpeng; Horimai, Hideyoshi; Lin, Xiao; Huang, Yong; Tan, Xiaodi

    2018-02-19

    A novel phase modulation method for holographic data storage with phase-retrieval reference beam locking is proposed and incorporated into an amplitude-encoding collinear holographic storage system. Unlike the conventional phase retrieval method, the proposed method locks the data page and the corresponding phase-retrieval interference beam together at the same location with a sequential recording process, which eliminates piezoelectric elements, phase shift arrays and extra interference beams, making the system more compact and phase retrieval easier. To evaluate our proposed phase modulation method, we recorded and then recovered data pages with multilevel phase modulation using two spatial light modulators experimentally. For 4-level, 8-level, and 16-level phase modulation, we achieved the bit error rate (BER) of 0.3%, 1.5% and 6.6% respectively. To further improve data storage density, an orthogonal reference encoding multiplexing method at the same position of medium is also proposed and validated experimentally. We increased the code rate of pure 3/16 amplitude encoding method from 0.5 up to 1.0 and 1.5 using 4-level and 8-level phase modulation respectively.

  2. Normalization of NDVI from Different Sensor System using MODIS Products as Reference

    International Nuclear Information System (INIS)

    Wenxia, Gan; Liangpei, Zhang; Wei, Gong; Huanfeng, Shen

    2014-01-01

    Medium Resolution NDVI(Normalized Difference Vegetation Index) from different sensor systems such as Landsat, SPOT, ASTER, CBERS and HJ-1A/1B satellites provide detailed spatial information for studies of ecosystems, vegetation biophysics, and land cover. Limitation of sensor designs, cloud contamination, and sensor failure highlighted the need to normalize and integrate NDVI from multiple sensor system in order to create a consistent, long-term NDVI data set. In this paper, we used a reference-based method for NDVI normalization. And present an application of this approach which covert Landsat ETM+ NDVI calculated by digital number (NDVI DN ) to NDVI calculated by surface reflectance (NDVI SR ) using MODIS products as reference, and different cluster was treated differently. Result shows that this approach can produce NDVI with highly agreement to NDVI calculated by surface reflectance from physical approaches based on 6S (Second Simulation of the satellite Signal in the Solar Spectrum). Although some variability exists, the cluster specified reference based approach shows considerable potential for NDVI normalization. Therefore, NDVI products in MODIS era from different sources can be combined for time-series analysis, biophysical parameter retrievals, and other downstream analysis

  3. Reference dosimetry for CT in the UK

    International Nuclear Information System (INIS)

    Shrimpton, P.C.; Wall, B.F.

    2001-01-01

    Computed tomography is firmly established as a major source of population exposure from diagnostic x-ray examinations and thus a particular focus for radiological protection initiatives. The concept of reference doses is widely recognised as a useful and practical tool for promoting improvements in the optimisation of protection for patients undergoing radiological examinations. National diagnostic reference levels (DRLs) have already been successfully applied in the UK for some conventional x-ray examinations within a framework for advice on patient protection. This approach is being extended to include CT, utilising the robust methodology for reference dosimetry that has been developed by the European Commission (EC) for the particular conditions of exposure in CT. This is based on the dosimetric concepts of weighted computed tomography dose index (CTDI w ) per slice in serial scanning or per rotation in helical scanning, and dose-length product (DLP) per complete examination. Notwithstanding some initial values proposed by the EC, specific national DRLs for CT practice in the UK will be established on the basis of widescale national survey data. (author)

  4. The Absolute Stability Analysis in Fuzzy Control Systems with Parametric Uncertainties and Reference Inputs

    Science.gov (United States)

    Wu, Bing-Fei; Ma, Li-Shan; Perng, Jau-Woei

    This study analyzes the absolute stability in P and PD type fuzzy logic control systems with both certain and uncertain linear plants. Stability analysis includes the reference input, actuator gain and interval plant parameters. For certain linear plants, the stability (i.e. the stable equilibriums of error) in P and PD types is analyzed with the Popov or linearization methods under various reference inputs and actuator gains. The steady state errors of fuzzy control systems are also addressed in the parameter plane. The parametric robust Popov criterion for parametric absolute stability based on Lur'e systems is also applied to the stability analysis of P type fuzzy control systems with uncertain plants. The PD type fuzzy logic controller in our approach is a single-input fuzzy logic controller and is transformed into the P type for analysis. In our work, the absolute stability analysis of fuzzy control systems is given with respect to a non-zero reference input and an uncertain linear plant with the parametric robust Popov criterion unlike previous works. Moreover, a fuzzy current controlled RC circuit is designed with PSPICE models. Both numerical and PSPICE simulations are provided to verify the analytical results. Furthermore, the oscillation mechanism in fuzzy control systems is specified with various equilibrium points of view in the simulation example. Finally, the comparisons are also given to show the effectiveness of the analysis method.

  5. Dosimetry for Patients undergoing Radiographic Examinations in Sudan

    International Nuclear Information System (INIS)

    Halato, M.A.; Kafi, S.T.; Ahmed, A.M.; Sid Ahamed, F.A.; Ibrahim, Z.; Suliman, M.F.; Suliman, I.I.

    2009-01-01

    In this study we estimated the entrance skin doses ESDs for patients undergoing selected diagnostic X -ray examinations in two large public hospitals in Khartoum state, Sudan. The study included the examinations of the chest posterior-anterior (PA) , skull antero-posterior (AP), skull Lateral (LAT) , Lumber spine AP/LAT, abdomen Intravenous urogram (IVU) and Pelvis AP. Totally, 241 patients were included in this study. ESDs were estimated from patients specific exposure parameters using established relation between output (μ Gy/mAs) and tube voltage (kVp). The estimated ESDs ranged from 0.18 - 1.05 mGy for chest PA, 0.98 - 3.48 mGy for Skull (AP), 0.66 - 2.75 mGy for skull (LAT), 1.22 - 4.35 mGy for abdomen (IVU), 1.18 - 5.75 mGy for Pelvis, 1.52 - 5.01 mGy Lumbar spine AP and 2.48 - 10.41 mGy for Lumbar spine (LAT). These values compare well with the international reference dose levels. This study provides additional data that can help the regulatory authority to establish reference dose level for diagnostic radiology in Sudan

  6. Normalization references for USEtoxTM-based toxic impact categories: North American and European economic systems

    DEFF Research Database (Denmark)

    Laurent, Alexis; Lautier, Anne; Rosenbaum, Ralph K.

    2011-01-01

    economic regions, North America and Europe, to calculate normalization references for the three currently-modelled USEtoxTM-based impact categories, i.e. freshwater ecotoxicity, human toxicity, divided into cancer effects and non-cancer effects. Base years for the references are 2004 for Europe and 2006...... coverage of organics in both the inventory and the CF databases. With respect to the intended global character of the USEtoxTM model, different approaches to determine normalization references of other economic systems (e.g. Asia or world) are discussed in relation to these findings. Overall, we thus...... recommend the use of the provided set of normalization references for USEtoxTM, but we also advocate 1) to perform an update as soon as a more comprehensive inventory can be obtained and as soon as characterization factors for metals are revised; 2) to consider extension to other economic systems in order...

  7. References for HNF-SD-WM-TRD-007, ''System specification for the double-shell tank system: HNF-PROs, CFRs, DOE Orders, WACs''

    International Nuclear Information System (INIS)

    Shaw, C.P.

    1998-01-01

    HNF-SD-WM-TRD-O07, System Specification for the Double-Shell Tank System, (hereafter referred to as DST Specification), defines the requirements of the double-shell tank system at the Hanford Site for Phase 1 privatization. Many of the sections in this document reference other documents for design guidance and requirements. Referenced documents include Project Hanford Management Contract (PHMC) procedures (HNF-PROS), Codes of Federal Regulation (CFRs), DOE Orders, and Washington Administrative Codes (WACs). This document provides rationale for the selection and inclusion of HNF-PROS, CFRs, DOE Orders and WACs

  8. Factors Related to Intention to Undergo Female Sterilization Among Married Women in Rural Kathmandu, Nepal.

    Science.gov (United States)

    Dhungana, Adhish; Nanthamongkolchai, Sutham; Pitikultang, Supachai

    2016-03-01

    Sterilization is most widely used fertility regulation method in Nepal. However, prevalence of uptake of female sterilization in central hilly region is less than the national average. The objective of the study was to explore the number and factors related to intention of married women to undergo female sterilization in rural Kathmandu which lies within central hilly region. This is a community based cross-sectional survey research conducted in rural area of Kathmandu valley. Two hundred and forty currently married women with at least one child of any age were interviewed using a structured pre-tested questionnaire. More than four-fifth of the respondents intended to undergo sterilization. Almost two-third of them wanted to limit their family size by taking this option. More than one-third of women not-intending to undergo sterilization feared weakness after sterilization. Age of the respondents, duration of marriage, and number of living children were significantly associated with intention to undergo sterilization. 15-24 years age group were six times more likely to have the intention for sterilization (OR 6.79, CI 2.28-20.19) compared to age 35 years and above group. Mothers with less than 3 living children are about three times more likely to have the intention to undergo sterilization (OR 2.87, CI 1.3-6.33) compared to women with more than 2 living children. Women married for 6 to 10 years were three times more likely to have the intention (OR 3.0, CI 1.09-8.27). However, gender of the living children was not associated with intention to undergo sterilization. There were significant numbers of women intending to undergo sterilization. Age of the mother, number of living children and the duration of marriage were found to be significantly influencing the intention to undergo sterilization. However, as intention refers to future plan, the respondents' intention may change over time. The national family planning program also needs to identify the key factors in

  9. Reference Concepts for a Space-Based Hydrogen-Oxygen Combustion, Turboalternator, Burst Power System

    National Research Council Canada - National Science Library

    Edenburn, Michael

    1990-01-01

    This report describes reference concepts for a hydrogen-oxygen combustion, turboalternator power system that supplies power during battle engagement to a space-based, ballistic missile defense platform...

  10. New reference object for metrological performance testing of industrial CT systems

    DEFF Research Database (Denmark)

    Müller, Pavel; Hiller, Jochen; Cantatore, Angela

    2012-01-01

    This paper presents a new reference object, so called “CT ball plate”, used for metrological performance testing of industrial CT systems, and discusses both the calibration procedure using a tactile coordinate measuring machine and the first results carried out using an industrial CT scanner....... This artefact can be used to determine several characteristics of the CT system like, probing errors of spheres, length measuring errors between sphere centers, measurement errors in the whole CT volume and effects in connection with image artefacts....

  11. Reference-tracking feedforward control design for linear dynamical systems through signal decomposition

    NARCIS (Netherlands)

    Kasemsinsup, Y.; Romagnoli, R.; Heertjes, M.F.; Weiland, S.; Butler, H.

    2017-01-01

    In this work, we study a novel approach towards the reference-tracking feedforward control design for linear dynamical systems. By utilizing the superposition property and exploiting signal decomposition together with a quadratic optimization process, we obtain a feedforward design procedure for

  12. Neural network-based model reference adaptive control system.

    Science.gov (United States)

    Patino, H D; Liu, D

    2000-01-01

    In this paper, an approach to model reference adaptive control based on neural networks is proposed and analyzed for a class of first-order continuous-time nonlinear dynamical systems. The controller structure can employ either a radial basis function network or a feedforward neural network to compensate adaptively the nonlinearities in the plant. A stable controller-parameter adjustment mechanism, which is determined using the Lyapunov theory, is constructed using a sigma-modification-type updating law. The evaluation of control error in terms of the neural network learning error is performed. That is, the control error converges asymptotically to a neighborhood of zero, whose size is evaluated and depends on the approximation error of the neural network. In the design and analysis of neural network-based control systems, it is important to take into account the neural network learning error and its influence on the control error of the plant. Simulation results showing the feasibility and performance of the proposed approach are given.

  13. Scalar material reference systems and loop quantum gravity

    International Nuclear Information System (INIS)

    Giesel, K; Thiemann, T

    2015-01-01

    In the past, the possibility to employ (scalar) material reference systems in order to describe classical and quantum gravity directly in terms of gauge invariant (Dirac) observables has been emphasized frequently. This idea has been picked up more recently in loop quantum gravity with the aim to perform a reduced phase space quantization of the theory, thus possibly avoiding problems with the (Dirac) operator constraint quantization method for a constrained system. In this work, we review the models that have been studied on the classical and/or the quantum level and parametrize the space of theories considered so far. We then describe the quantum theory of a model that, to the best of our knowledge, has only been considered classically so far. This model could arguably be called the optimal one in this class of models considered as it displays the simplest possible true Hamiltonian, while at the same time reducing all constraints of general relativity. (paper)

  14. Prospect theory, reference points, and health decisions

    Directory of Open Access Journals (Sweden)

    Alan Schwartz

    2008-02-01

    Full Text Available In preventative health decisions, such as the decision to undergo an invasive screening test or treatment, people may be deterred from selecting the test because its perceived disutility relative to not testing is greater than the utility associated with prevention of possible disease. The prospect theory editing operation, by which a decision maker's reference point is determined, can have important effects on the disutility of the test. On the basis of the prospect theory value function, this paper develops two approaches to reducing disutility by directing the decision maker's attention to either (actual past or (expected future losses that result in shifted reference points. After providing a graphical description of the approaches and a mathematical proof of the direction of their effect on judgment, we briefly illustrate the potential value of these approaches with examples from qualitative research on prostate cancer treatment decisions.

  15. Pediatric reference value distributions and covariate-stratified reference intervals for 29 endocrine and special chemistry biomarkers on the Beckman Coulter Immunoassay Systems: a CALIPER study of healthy community children.

    Science.gov (United States)

    Karbasy, Kimiya; Lin, Danny C C; Stoianov, Alexandra; Chan, Man Khun; Bevilacqua, Victoria; Chen, Yunqi; Adeli, Khosrow

    2016-04-01

    The CALIPER program is a national research initiative aimed at closing the gaps in pediatric reference intervals. CALIPER previously reported reference intervals for endocrine and special chemistry markers on Abbott immunoassays. We now report new pediatric reference intervals for immunoassays on the Beckman Coulter Immunoassay Systems and assess platform-specific differences in reference values. A total of 711 healthy children and adolescents from birth to reference intervals calculated in accordance with Clinical and Laboratory Standards Institute (CLSI) EP28-A3c guidelines. Complex profiles were observed for all 29 analytes, necessitating unique age and/or sex-specific partitions. Overall, changes in analyte concentrations observed over the course of development were similar to trends previously reported, and are consistent with biochemical and physiological changes that occur during childhood. Marked differences were observed for some assays including progesterone, luteinizing hormone and follicle-stimulating hormone where reference intervals were higher than those reported on Abbott immunoassays and parathyroid hormone where intervals were lower. This study highlights the importance of determining reference intervals specific for each analytical platform. The CALIPER Pediatric Reference Interval database will enable accurate diagnosis and laboratory assessment of children monitored by Beckman Coulter Immunoassay Systems in health care institutions worldwide. These reference intervals must however be validated by individual labs for the local pediatric population as recommended by CLSI.

  16. Modification of reference temperature program in reactor regulating system

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Sung Sik; Lee, Byung Jin; Kim, Se Chang; Cheong, Jong Sik [Korea Power Engineering Company, Inc., Seoul (Korea, Republic of); Kim, Ji In; Doo, Jin Yong [Korea Electric Power Cooperation, Yonggwang (Korea, Republic of)

    1999-12-31

    In Yonggwang nuclear units 3 and 4 currently under commercial operation, the cold temperature was very close to the technical specification limit of 298 deg C during initial startup testing, which was caused by the higher-than-expected reactor coolant system flow. Accordingly, the reference temperature (Tref) program needed to be revised to allow more flexibility for plant operations. In this study, the method of a specific test performed at Yonggwang nuclear unit 4 to revise the Tref program was described and the test results were discussed. In addition, the modified Tref program was evaluated on its potential impacts on system performance and safety. The methods of changing the Tref program and the associated pressurizer level setpoint program were also explained. Finally, for Ulchin nuclear unit 3 and 4 currently under initial startup testing, the effects of reactor coolant system flow rate on the coolant temperature were evaluated from the thermal hydraulic standpoint and an optimum Tref program was recommended. 6 refs., 4 figs., 2 tabs. (Author)

  17. Modification of reference temperature program in reactor regulating system

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Sung Sik; Lee, Byung Jin; Kim, Se Chang; Cheong, Jong Sik [Korea Power Engineering Company, Inc., Seoul (Korea, Republic of); Kim, Ji In; Doo, Jin Yong [Korea Electric Power Cooperation, Yonggwang (Korea, Republic of)

    1998-12-31

    In Yonggwang nuclear units 3 and 4 currently under commercial operation, the cold temperature was very close to the technical specification limit of 298 deg C during initial startup testing, which was caused by the higher-than-expected reactor coolant system flow. Accordingly, the reference temperature (Tref) program needed to be revised to allow more flexibility for plant operations. In this study, the method of a specific test performed at Yonggwang nuclear unit 4 to revise the Tref program was described and the test results were discussed. In addition, the modified Tref program was evaluated on its potential impacts on system performance and safety. The methods of changing the Tref program and the associated pressurizer level setpoint program were also explained. Finally, for Ulchin nuclear unit 3 and 4 currently under initial startup testing, the effects of reactor coolant system flow rate on the coolant temperature were evaluated from the thermal hydraulic standpoint and an optimum Tref program was recommended. 6 refs., 4 figs., 2 tabs. (Author)

  18. Effect of nutritional status on mortality in patients undergoing coronary artery bypass grafting.

    Science.gov (United States)

    Keskin, Muhammed; İpek, Göktük; Aldağ, Mustafa; Altay, Servet; Hayıroğlu, Mert İlker; Börklü, Edibe Betül; İnan, Duygu; Kozan, Ömer

    2018-04-01

    The prognostic effects of poor nutritional status and cardiac cachexia on coronary artery disease (CAD) are not clearly understood. A well-accepted nutritional status parameter, the prognostic nutritional index (PNI), which was first demonstrated to be valuable in patients with cancer and those undergoing gastrointestinal surgery, was introduced to patients requiring coronary artery bypass grafting (CABG). The aim of the present study was to evaluate the prognostic value of PNI in patients with CAD undergoing CABG. We evaluated the in-hospital and long-term (3-y) prognostic effect of PNI on 644 patients with CAD undergoing CABG. Baseline characteristics and outcomes were compared among the patients by PNI and categorized accordingly: Q1, Q2, Q3, and Q4. Patients with lower PNI had significantly higher in-hospital and long-term mortality. Patients with lower PNI levels (Q1) had higher in-hospital mortality and had 12 times higher mortality rates than those with higher PNI levels (Q4). The higher PNI group had the lower rates and was used as the reference. Long-term mortality was higher in patients with lower PNI (Q1)-4.9 times higher than in the higher PNI group (Q4). In-hospital and long-term mortality rates were similar in the non-lower PNI groups (Q2-4). The present study demonstrated that PNI, calculated based on serum albumin level and lymphocyte count, is an independent prognostic factor for mortality in patients undergoing CABG. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Handbook of reference electrodes

    CERN Document Server

    Inzelt, György; Scholz, Fritz

    2013-01-01

    Reference Electrodes are a crucial part of any electrochemical system, yet an up-to-date and comprehensive handbook is long overdue. Here, an experienced team of electrochemists provides an in-depth source of information and data for the proper choice and construction of reference electrodes. This includes all kinds of applications such as aqueous and non-aqueous solutions, ionic liquids, glass melts, solid electrolyte systems, and membrane electrodes. Advanced technologies such as miniaturized, conducting-polymer-based, screen-printed or disposable reference electrodes are also covered. Essen

  20. Towards a reference ontology of complex economic exchanges for Accounting Information Systems

    NARCIS (Netherlands)

    Blums, Ivar; Weigand, Hans; Matthes, Flores; Mendling, Jan; Rinderle-Ma, Stefanie

    Although the field of Accounting Information Systems (AIS) has a long tradition, there is still a lack of a widely adopted conceptualization. The Unified Foundational Ontology (UFO) and its Services sub- ontology (UFO-S) are regarded as grounding the engineering of a reference ontology for AIS. The

  1. An analytic-numerical method for the construction of the reference law of operation for a class of mechanical controlled systems

    Science.gov (United States)

    Mizhidon, A. D.; Mizhidon, K. A.

    2017-04-01

    An analytic-numerical method for the construction of a reference law of operation for a class of dynamic systems describing vibrations in controlled mechanical systems is proposed. By the reference law of operation of a system, we mean a law of the system motion that satisfies all the requirements for the quality and design features of the system under permanent external disturbances. As disturbances, we consider polyharmonic functions with known amplitudes and frequencies of the harmonics but unknown initial phases. For constructing the reference law of motion, an auxiliary optimal control problem is solved in which the cost function depends on a weighting coefficient. The choice of the weighting coefficient ensures the design of the reference law. Theoretical foundations of the proposed method are given.

  2. Global Reference Tables for Production Systems

    Data.gov (United States)

    Social Security Administration — This database is a collection of reference tables that store common information used throughout SSA. These tables standardized code structures and code usage of SSA...

  3. Terminological reference of a knowledge-based system: the data dictionary.

    Science.gov (United States)

    Stausberg, J; Wormek, A; Kraut, U

    1995-01-01

    The development of open and integrated knowledge bases makes new demands on the definition of the used terminology. The definition should be realized in a data dictionary separated from the knowledge base. Within the works done at a reference model of medical knowledge, a data dictionary has been developed and used in different applications: a term definition shell, a documentation tool and a knowledge base. The data dictionary includes that part of terminology, which is largely independent of a certain knowledge model. For that reason, the data dictionary can be used as a basis for integrating knowledge bases into information systems, for knowledge sharing and reuse and for modular development of knowledge-based systems.

  4. Implementation of a system for external audits beam radiation therapy in terms of reference no

    International Nuclear Information System (INIS)

    Alonso Samper, Jose Luis; Dominguez, Lourdes; Alert Silva, Jose; Alfonso Laguardia, Rodolfo; Larrinaga Cortina, Eduardo; Garcia Yip, Fernando; Rodriguez Machado, Jorge; Morales Lopez, Jorge Luis; Silvestre Patallo, Ileana

    2009-01-01

    This paper presents our experience in implementing a external audit system for radiotherapy beam in no reference conditions with the use of CIRS and a summary of the measurements with him made.This paper presents our experience in implementing a external audit system for radiotherapy beam in no reference conditions with the use of CIRS and a summary of the measurements with him made. Centers were audited with external beam high-energy Co-60, 6 MV and 15 MV and were considered 4 treatment planning systems (TPS): AMEPLAN, Theraplan Plus, Precise Plan and MIRS to calculate doses prescribed in each test case. All measurements were acquired by the audit team using the anthropomorphic phantom CIRS, Semiflex chamber PTW 31010 and PTW electrometer STATES. The implementation and development of the external audits of beams radiotherapy in terms of 'no reference' has brought an improvement in both clinical aspects of treatment and the radiation safety and the quality control, has given us greater confidence and for this reason we believe has become essential. (Author)

  5. Real-time observation of fluctuations in a driven-dissipative quantum many-body system undergoing a phase transition

    Science.gov (United States)

    Donner, Tobias

    2015-03-01

    A Bose-Einstein condensate whose motional degrees of freedom are coupled to a high-finesse optical cavity via a transverse pump beam constitutes a dissipative quantum many-body system with long range interactions. These interactions can induce a structural phase transition from a flat to a density-modulated state. The transverse pump field simultaneously represents a probe of the atomic density via cavity- enhanced Bragg scattering. By spectrally analyzing the light field leaking out of the cavity, we measure non-destructively the dynamic structure factor of the fluctuating atomic density while the system undergoes the phase transition. An observed asymmetry in the dynamic structure factor is attributed to the coupling to dissipative baths. Critical exponents for both sides of the phase transition can be extracted from the data. We further discuss our progress in adding strong short-range interactions to this system, in order to explore Bose-Hubbard physics with cavity-mediated long-range interactions and self-organization in lower dimensions.

  6. From the LHC Reference Database to the Powering Interlock System

    CERN Document Server

    Dehavay, C; Schmidt, R; Veyrunes, E; Zerlauth, M

    2003-01-01

    The protection of the magnet powering system for the Large Hadron Collider (LHC) currently being built at CERN is a major challenge due to the unprecedented complexity of the accelerator. The Powering Interlock System of the LHC will have to manage more than 1600 DC circuits for magnet powering, different in their structure, complexity and importance to the accelerator. For the coherent description of such complex system, a Reference Database as unique source of the parameters of the electrical circuits has been developed. The information, introduced via a generic circuit description language, is first used for installing the accelerator and making all electrical connections. The data is then used for tests and commissioning. During operation, the Powering Interlock System manages all critical functions. It consists of 36 PLC based controllers dis tributed around the machine and requires a flexible and transparent way of configuration, since each controller manages different numbers and types of electrical ci...

  7. Establishing diagnostic reference levels in digital radiology

    International Nuclear Information System (INIS)

    Bana, Remy Wilson

    2016-04-01

    Medical application of radiation has gained wider study since diagnostic radiology plays a very important role in modern medicine. The need of the service seems to increase since the invention of digital radiology as a new technology that promises greater accuracy while minimizing patient dose. However, it is not exempted in the harmonization of doses delivered to the patient undergoing same radiologic examination in different institutions either regional or nationwide. The objective of this project was to review the establishment of Diagnostic Reference Levels (DRLs) in digital radiology at National level with the aim to reduce patient dose while maintaining appropriate image quality. A general discussion on digital radiology has been presented focusing on the optimization of patient dose as well as dosimetric quantities used for the establishment of DRLs. Recommendations have been provided for Rwanda to initiate steps to establish National Diagnostic Reference Levels for common procedures in digital radiology. (au)

  8. Enhanced electricity system analysis for decision making - A reference book

    International Nuclear Information System (INIS)

    2000-01-01

    The objective of electricity system analysis in support of decision making is to provide comparative assessment results upon which relevant policy choices between alternative technology options and supply strategies can be based. This reference book offers analysts, planners and decision makers documented information on enhanced approaches to electricity system analysis, that can assist in achieving this objective. The book describes the main elements of comprehensive electricity system analysis and outlines an advanced integrated analysis and decision making framework for the electric power sector. Emphasis is placed on mechanisms for building consensus between interested and affected parties, and on aspects of planning that go beyond the traditional economic optimisation approach. The scope and contents of the book cover the topics to be addressed in decision making for the power sector and the process of integrating economic, social, health and environmental aspects in the comparative assessment of alternative options and strategies. The book describes and discusses overall frameworks, processes and state of the art methods and techniques available to analysts and planners for carrying out comparative assessment studies, in order to provide sound information to decision makers. This reference book is published as part of a series of technical reports and documents prepared in the framework of the inter-agency joint project (DECADES) on databases and methodologies for comparative assessment of different energy sources for electricity generation. The overall objective of the DECADES project is to enhance capabilities for incorporating economic, social, health and environmental issues in the comparative assessment of electricity generation options and strategies in the process of decision making for the power sector. The project, established in 1992, is carried out jointly by the European Commission (EC), the Economic and Social Commission for Asia and the Pacific

  9. Disturbance rejection performance analyses of closed loop control systems by reference to disturbance ratio.

    Science.gov (United States)

    Alagoz, Baris Baykant; Deniz, Furkan Nur; Keles, Cemal; Tan, Nusret

    2015-03-01

    This study investigates disturbance rejection capacity of closed loop control systems by means of reference to disturbance ratio (RDR). The RDR analysis calculates the ratio of reference signal energy to disturbance signal energy at the system output and provides a quantitative evaluation of disturbance rejection performance of control systems on the bases of communication channel limitations. Essentially, RDR provides a straightforward analytical method for the comparison and improvement of implicit disturbance rejection capacity of closed loop control systems. Theoretical analyses demonstrate us that RDR of the negative feedback closed loop control systems are determined by energy spectral density of controller transfer function. In this manner, authors derived design criteria for specifications of disturbance rejection performances of PID and fractional order PID (FOPID) controller structures. RDR spectra are calculated for investigation of frequency dependence of disturbance rejection capacity and spectral RDR analyses are carried out for PID and FOPID controllers. For the validation of theoretical results, simulation examples are presented. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.

  10. The Uhlenbeck-Ford model: Exact virial coefficients and application as a reference system in fluid-phase free-energy calculations

    Science.gov (United States)

    Paula Leite, Rodolfo; Freitas, Rodrigo; Azevedo, Rodolfo; de Koning, Maurice

    2016-11-01

    The Uhlenbeck-Ford (UF) model was originally proposed for the theoretical study of imperfect gases, given that all its virial coefficients can be evaluated exactly, in principle. Here, in addition to computing the previously unknown coefficients B11 through B13, we assess its applicability as a reference system in fluid-phase free-energy calculations using molecular simulation techniques. Our results demonstrate that, although the UF model itself is too soft, appropriately scaled Uhlenbeck-Ford (sUF) models provide robust reference systems that allow accurate fluid-phase free-energy calculations without the need for an intermediate reference model. Indeed, in addition to the accuracy with which their free energies are known and their convenient scaling properties, the fluid is the only thermodynamically stable phase for a wide range of sUF models. This set of favorable properties may potentially put the sUF fluid-phase reference systems on par with the standard role that harmonic and Einstein solids play as reference systems for solid-phase free-energy calculations.

  11. Calibration of a multi-beam Laser System by using a TLS-generated Reference

    Directory of Open Access Journals (Sweden)

    M. Gordon

    2013-10-01

    Full Text Available Rotating multi-beam LIDARs mounted on moving platforms have become very successful for many applications such as autonomous navigation, obstacle avoidance or mobile mapping. To obtain accurate point coordinates, a precise calibration of such a LIDAR system is required. For the determination of the corresponding parameters we propose a calibration scheme which exploits the information of 3D reference point clouds captured by a terrestrial laser scanning (TLS device. It is assumed that the accuracy of this point clouds is considerably higher than that from the multi-beam LIDAR and that the data represent faces of man-made objects at different distances. After extracting planes in the reference data sets, the point-plane-incidences of the measured points and the reference planes are used to formulate the implicit constraints. We inspect the Velodyne HDL-64E S2 system as the best-known representative for this kind of sensor system. The usability and feasibility of the calibration procedure is demonstrated with real data sets representing building faces (walls, roof planes and ground. Beside the improvement of the point accuracy by considering the calibration results, we test the significance of the parameters related to the sensor model and consider the uncertainty of measurements w.r.t. the measured distances. The Velodyne returns two kinds of measurements – distances and encoder angles. To account for this, we perform a variance component estimation to obtain realistic standard deviations for the observations.

  12. 77 FR 76045 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-12-26

    ... case classification (disease staging system). Recommendations for revisions in the case definition were... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-13-0573] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention...

  13. Moving Reference to the Web.

    Science.gov (United States)

    McGlamery, Susan; Coffman, Steve

    2000-01-01

    Explores the possibility of using Web contact center software to offer reference assistance to remote users. Discusses a project by the Metropolitan Cooperative Library System/Santiago Library System consortium to test contact center software and to develop a virtual reference network. (Author/LRW)

  14. Global Area Reference System (GARS), 30-minute Blocks for Louisiana, WGS84, NGA (2007) [gars_la_30min_nga_2007

    Data.gov (United States)

    Louisiana Geographic Information Center — Global Area Reference System (GARS) is developed by the National Geospatial-Intelligence Agency (NGA) as an area reference system. GARS is based on lines of...

  15. Evaluation of the prognostic value of Okuda, Cancer of the Liver Italian Program, and Japan Integrated Staging systems for hepatocellular carcinoma patients undergoing radiotherapy

    International Nuclear Information System (INIS)

    Seong, Jinsil; Shim, Su Jung; Lee, Ik Jae; Han, Kwang Hyub; Chon, Chae Yoon; Ahn, Sang Hoon

    2007-01-01

    Purpose: The purpose of this study was to compare the validity of staging systems, as well as to identify the staging system with the best prognostic value, in hepatocellular carcinoma (HCC) patients treated with radiotherapy. Methods and Materials: From 1992 to 2003, a total of 305 patients undergoing radiotherapy for HCC were evaluated retrospectively. All patients were classified before radiation therapy by the following systems: tumor-node-metastasis (TNM), Okuda, Cancer of the Liver Italian Program (CLIP), and Japan Integrated Staging (JIS) score. Cumulative survival rates were obtained using the Kaplan-Meier method, and were statistically compared using the log-rank test. Results: Median survival time was 11 months. The 1-, 2-, 3-, 4-, and 5-year survival rates were 45.1%, 24.5%, 14.7%, 10.3%, and 6.4%, respectively. Significant differences in survival were observed between all TNM stages, between CLIP scores 2, 3 and 5, 6, as well as between JIS scores 1, 2, and 2, 3. Conclusions: Among the systems studied, the TNM staging approach appeared to be the best predictor of prognosis. Staging systems that reflect liver disease status (Okuda stage, CLIP, and JIS score) showed limitations in stratifying patients undergoing radiotherapy into different prognostic groups

  16. On-board landmark navigation and attitude reference parallel processor system

    Science.gov (United States)

    Gilbert, L. E.; Mahajan, D. T.

    1978-01-01

    An approach to autonomous navigation and attitude reference for earth observing spacecraft is described along with the landmark identification technique based on a sequential similarity detection algorithm (SSDA). Laboratory experiments undertaken to determine if better than one pixel accuracy in registration can be achieved consistent with onboard processor timing and capacity constraints are included. The SSDA is implemented using a multi-microprocessor system including synchronization logic and chip library. The data is processed in parallel stages, effectively reducing the time to match the small known image within a larger image as seen by the onboard image system. Shared memory is incorporated in the system to help communicate intermediate results among microprocessors. The functions include finding mean values and summation of absolute differences over the image search area. The hardware is a low power, compact unit suitable to onboard application with the flexibility to provide for different parameters depending upon the environment.

  17. Completed Gravity Probe B Undergoes Thermal Vacuum Testing

    Science.gov (United States)

    2000-01-01

    The Gravity Probe B (GP-B) is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. In this photograph, the completed space vehicle is undergoing thermal vacuum environment testing. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Launched April 20, 2004 , the GP-B program was managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Russ Underwood, Lockheed Martin Corporation.)

  18. 75 FR 20601 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-04-20

    .... Proposed Project Asthma Information Reporting System (AIRS)--New--Air Pollution and Respiratory Health... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-10-09CK] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and prevention...

  19. 78 FR 24422 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-04-25

    ... System (AIRS) (0920-0853, Expiration 06/30/2013)--Extension--Air Pollution and Respiratory Health Branch... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-13-0853] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention...

  20. Fast breeder reactor reference system classification for the ENEA data bank

    International Nuclear Information System (INIS)

    Righini, R.

    1988-01-01

    This report contains the Reference System Classification (RSC) of fast breeder reactors: it provides a functional system breakdown of the reactor. For each system the following important characteristics are reported: the main function, the mode of operation, its location in the reactor, the main interface system, its main components and the component working environment (fluid and/or atmosphere type). The RSC represent a basic step in organizing the ENEA data bank for the registration and processing of reliability data on typical fast reactor components; it provides a functional component breakdown and represent a plant-unique identification in the process of omogenization of event-data coming from different reactors. In this report it was tried to take into account different generations of nuclear power plants, different plant layouts and solutions: in particular loop and pool reactors are separately treated

  1. Adaptive Control with Reference Model Modification

    Science.gov (United States)

    Stepanyan, Vahram; Krishnakumar, Kalmanje

    2012-01-01

    This paper presents a modification of the conventional model reference adaptive control (MRAC) architecture in order to improve transient performance of the input and output signals of uncertain systems. A simple modification of the reference model is proposed by feeding back the tracking error signal. It is shown that the proposed approach guarantees tracking of the given reference command and the reference control signal (one that would be designed if the system were known) not only asymptotically but also in transient. Moreover, it prevents generation of high frequency oscillations, which are unavoidable in conventional MRAC systems for large adaptation rates. The provided design guideline makes it possible to track a reference commands of any magnitude from any initial position without re-tuning. The benefits of the method are demonstrated with a simulation example

  2. An update to the analysis of the Canadian Spatial Reference System

    Science.gov (United States)

    Ferland, R.; Piraszewski, M.; Craymer, M.

    2015-12-01

    The primary objective of the Canadian Spatial Reference System (CSRS) is to provide users access to a consistent geo-referencing infrastructure over the Canadian landmass. Global Navigation Satellite System (GNSS) positioning accuracy requirements ranges from meter level to mm level (e.g.: crustal deformation). The highest level of the Canadian infrastructure consist of a network of continually operating GPS and GNSS receivers, referred to as active control stations. The network includes all Canadian public active control stations, some bordering US CORS and Alaska stations, Greenland active control stations, as well as a selection of IGS reference frame stations. The Bernese analysis software is used for the daily processing and the combination into weekly solutions which form the basis for this analysis. IGS weekly final orbit, Earth Rotation parameters (ERP's) and coordinates products are used in the processing. For the more demanding users, the time dependant changes of station coordinates is often more important.All station coordinate estimates and related covariance information is used in this analysis. For each input solution, variance factor, translation, rotation and scale (and if needed their rates) or subsets of these are estimated. In the combination of these weekly solutions, station positions and velocities are estimated. Since the time series from the stations in these networks often experience changes in behavior, new (or reuse of) parameters are generally used in these situations. As is often the case with real data, unrealistic coordinates may occur. Automatic detection and removal of outliers is used in these cases. For the transformation, position and velocity parameters loose apriori estimates and uncertainties are provided. Alignment using the usual Helmert transformation to the latest IGb08 realization of ITRF is also performed during the adjustment.

  3. Rate of alignment and communication using quantum systems in the absence of a shared frame of reference

    Science.gov (United States)

    Skotiniotis, Michael

    Quantum information theory is concerned with the storage, transmission, and manipulation of information that is represented in the degrees of freedom of quantum systems. These degrees of freedom are described relative to an external frame of reference. The lack of a requisite frame of reference imposes restrictions on the types of states quantum systems can be prepared in and the type of operations that can be performed on quantum systems. This thesis is concerned with the communication between two parties that lack a shared frame of reference. Specifically, I introduce a protocol whereby the parties can align their respective frames of reference, and a protocol for communicating quantum information in a reference frame independent manner. Using the accessible information to quantify the success of a reference frame alignment protocol I propose a new measure—the alignment rate—for quantifying the ability of a quantum state to stand in place of a classical frame of reference. I show that for the case where Alice and Bob lack a shared frame of reference associated with the groups G = U(1) and G = ZM (the finite cyclic group of M elements), the alignment rate is equal to the regularized, linearized G-asymmetry. The latter is a unique measure of the frameness of a quantum state and my result provides an operational interpretation of the G-asymmetry that was thus far lacking. In addition, I show that the alignment rate for finite cyclic groups of more than three elements is super-additive under the tensor product of two distinct pure quantum states. The latter is, to my knowledge, the first instance of a regularized quantity that exhibits super-additivity. In addition, I propose a reference-frame-independent protocol for communicating quantum information in the absence of a shared frame of reference associated with a general finite group G. The protocol transmits m logical qudits using r + m physical qudits prepared in a specific state that is reference

  4. A national survey of supportive practices for patients undergoing radiotherapy for oral cancers

    International Nuclear Information System (INIS)

    Osborn, Joanne; Doolan, Caroline

    2013-01-01

    Purpose: Xerostomia and mucositis are two of the main radiation induced toxicities experienced by patients undergoing radiotherapy to the oral cavity. These toxicities can lead to significant weight loss with the potential to cause complications with radiotherapy treatment. Literature has shown that nutritional intervention can help to minimise these side effects. The aim of the survey was to explore current practice across the UK in nutritional intervention for these patients. Method: Postal questionnaires were sent to all 63 radiotherapy departments in the UK in November 2009. Results: 29 responses (43%) were received. 90% (n = 26) of the departments used 3D-Conformal radiotherapy (3D-CRT) as the main technique for treatment of these patients, with 48% (n = 14) of departments having implemented Intensity modulated radiotherapy (IMRT). All departments referred their patients to a dietician. 93% (n = 27) of departments placed percutaneous endoscopic gastrostomy or radiologically-inserted gastrostomy tubes. 55% (n = 16) departments administered nasogastric tubes. Conclusion: This survey verified many common practices regarding dietary care and advice, some variation was evident in the use of feeding tubes. All responding centres referred patients to a dietician with the aim to maintain nutritional status and prevent weight loss that could contribute to uncertainty in treatment setup. This survey also demonstrated that since Macknelly and Day's (2009) study, a greater number of centres have implemented IMRT for patients undergoing radiotherapy to the head and neck. Although IMRT has been shown to reduce xerostomia, this audit found no changes in the dietary care and advice given to these patients

  5. Specifications for trueness and precision of a reference measurement system for serum/plasma 25-hydroxyvitamin D analysis.

    Science.gov (United States)

    Stöckl, Dietmar; Sluss, Patrick M; Thienpont, Linda M

    2009-10-01

    The divergence in analytical quality of serum/plasma 25-hydroxy-vitamin D analysis calls for defining specifications for a reference measurement system. Fundamentally, in a reference measurement system, there should be a relationship between the analytical specifications for higher- (reference) and lower-order (routine) measurements. Therefore, when setting specifications, we started with limits for routine imprecision (CV(rou)) and bias (B(rou)) using 4 models: (1) the misclassifications in diagnosis, (2) biological variation data (reference interval (RI) and monitoring), (3) expert recommendations, and (4) state-of-the-art performance. Then, we used the derived goals to tailor those for reference measurements and certified reference materials (CRMs) for calibration by setting the limits for CV(ref) at 0.5 CV(rou), B(ref) at 0.33 B(rou)(,) max. uncertainty (U(max)) at 0.33 B(ref). The established specifications ranged between CV(rou)model 3) and CV(rou)model 2, monitoring). Model 2 (monitoring) gave the most stringent goals, model 3, the most liberal ones. Accounting for state-of-the-art performance and certification capabilities, we used model 2 (RI) to recommend achievable goals: for routine testing, CV(rou)measurements, CV(ref)

  6. Investigation on Reference Frames and Time Systems in Multi-GNSS

    Directory of Open Access Journals (Sweden)

    Luca Nicolini

    2018-01-01

    Full Text Available Receivers able to track satellites belonging to different GNSSs (Global Navigation Satellite Systems are available on the market. To compute coordinates and velocities it is necessary to identify all the elements that contribute to interoperability of the different GNSSs. For example the timescales kept by different GNSSs have to be aligned. Receiver-specific biases, or firmware-dependent biases, need to be calibrated. The reference frame used in the representation of the orbits must be unique. In this paper we address the interoperability issues from the standpoint of a Single Point Positioning (SPP user, i.e., using pseudoranges and broadcast ephemeris. The biases between GNSSs timescales and receiver-dependent biases are analyzed for a set of 31 MGEX (Multi-GNSS Experiment stations over a time span of more than three years. Time series of biases between timescales of GPS (Global Positioning System, GLONASS (Global Navigation Satellite System, Galileo, BeiDou, QZSS (Quasi-Zenith Satellite System, SBAS (Satellite Based Augmentation System and NAVIC (Navigation with Indian Constellation are investigated, in addition to the identification of events like discontinuity of receiver-dependent biases due to firmware updating. The GPS broadcast reference frame is shown to be aligned to the one (IGS14 realized by the precise ephemeris of CODE (Center for Orbit Determination in Europe to within 0.1 m and 2 milliarcsec, with values dependent on whether IIR-A, IIR-B/M or IIF satellite blocks are considered. Larger offsets are observed for GLONASS, up to 1 m for GLONASS K satellites. For Galileo the alignment of the broadcast orbit to IGS14/CODE is again at the 0.1 m and several milliarcsec level, with the FOC (Full Operational Capability satellites slightly better than IOV (In Orbit Validation. For BeiDou an alignment of the broadcast frame to IGS14/CODE comparable to GLONASS is observed, regardless of whether IGSO (Inclined Geosynchronous Orbit or MEO

  7. Establishing an individual dosing system for patients undergoing interventional transcatheter arterial embolization: Radiochromic film and Monte Carlo simulation

    International Nuclear Information System (INIS)

    Tsai, Hui-Yu; Lai, Pei-Ling; Li, Yang-Ying; Tyan, Yeu-Sheng

    2011-01-01

    Less invasive imaging-guided vascular interventions with fluoroscopy and digital subtraction angiography have recently become widespread and have been successfully used for treating various diseases. However, interventional fluoroscopy procedures may present deterministic and stochastic radiation risks. The International Commission on Radiological Protection (ICRP) and the Food and Drug Administration have requested identifying procedures that may involve patient doses greater than the recommended thresholds. In this study, radiochromic dosimetric media, known as self-developing films, and measurement-based Monte Carlo simulations were used to establish an interventional radiology dosing system for individual patients undergoing interventional transcatheter arterial embolization. The peak skin dose, evaluated from the entrance surface dose distribution, was 21% less than the cumulated dose reported from the console. A 3D dose map incorporated into CT images was established. The organ doses and effective doses for individual patients were evaluated using this dosing system. This system could be applied very well to other fluoroscopic or interventional procedures for patient dose management.

  8. A Proposal of New Reference System for the Standard Axial, Sagittal, Coronal Planes of Brain Based on the Serially-Sectioned Images

    Science.gov (United States)

    Park, Jin Seo; Park, Hyo Seok; Shin, Dong Sun; Har, Dong-Hwan; Cho, Zang-Hee; Kim, Young-Bo; Han, Jae-Yong; Chi, Je-Geun

    2010-01-01

    Sectional anatomy of human brain is useful to examine the diseased brain as well as normal brain. However, intracerebral reference points for the axial, sagittal, and coronal planes of brain have not been standardized in anatomical sections or radiological images. We made 2,343 serially-sectioned images of a cadaver head with 0.1 mm intervals, 0.1 mm pixel size, and 48 bit color and obtained axial, sagittal, and coronal images based on the proposed reference system. This reference system consists of one principal reference point and two ancillary reference points. The two ancillary reference points are the anterior commissure and the posterior commissure. And the principal reference point is the midpoint of two ancillary reference points. It resides in the center of whole brain. From the principal reference point, Cartesian coordinate of x, y, z could be made to be the standard axial, sagittal, and coronal planes. PMID:20052359

  9. Initial Stage Reference Search : Driver Simulators to Test Shared Controls, Limited Autonomy Vehicle Systems

    Science.gov (United States)

    2015-09-01

    This literature review and reference scanning focuses on the use of driver simulators for semiautonomous (or shared control) vehicle systems (2012present), including related research from other modes of transportation (e.g., rail or aviation). Foc...

  10. DESIGN OF ROBUST NAVIGATION AND STABILIZATION LOOPS OF PRECISION ATTITUDE AND HEADING REFERENCE SYSTEM

    Directory of Open Access Journals (Sweden)

    Olha Sushchenko

    2017-11-01

    Full Text Available Purpose: The paper focuses on problems of design of robust precision attitude and heading reference systems, which can be applied in navigation of marine vehicles. The main goal is to create the optimization procedures for design of navigation and stabilization loops of the multimode gimballed system. The optimization procedure of the navigation loop design is based on the parametric robust H2/H∞-optimization. The optimization procedure of the stabilization loop design is based on the robust structural H∞-synthesis. Methods: To solve the given problem the methods of the robust control system theory and optimization methods are used. Results: The kinematical scheme of the precision gimballed attitude and heading reference system is represented. The parametrical optimization algorithm taking into consideration features of the researched system is given. Method of the mixed sensitivity relative to the researched system design is analyzed. Coefficients of the control laws of navigation loops are obtained based on optimization procedure providing compromise between accuracy and robustness. The robust controller of the stabilization loop was developed based on robust structural synthesis using method of the mixed sensitivity. Simulation of navigation and stabilization processes is carried out. Conclusions: The represented results prove efficiency of the proposed procedures, which can be useful for design of precision navigation systems of the moving vehicles.

  11. Venous, Arterialized-Venous, or Capillary Glucose Reference Measurements for the Accuracy Assessment of a Continuous Glucose Monitoring System.

    Science.gov (United States)

    Kropff, Jort; van Steen, Sigrid C; deGraaff, Peter; Chan, Man W; van Amstel, Rombout B E; DeVries, J Hans

    2017-11-01

    Different reference methods are used for the accuracy assessment of continuous glucose monitoring (CGM) systems. The effect of using venous, arterialized-venous, or capillary reference measurements on CGM accuracy is unclear. We evaluated 21 individuals with type 1 diabetes using a capillary calibrated CGM system. Venous or arterialized-venous reference glucose samples were taken every 15 min at two separate visits and assessed per YSI 2300 STAT Plus. Arterialization was achieved by heated-hand technique. Capillary samples were collected hourly during the venous reference visit. The investigation sequence (venous or arterialized-venous) was randomized. Effectiveness of arterialization was measured by comparing free venous oxygen pressure (PO2) of both visit days. Primary endpoint was the median absolute relative difference (ARD). Median ARD using arterialized-venous reference samples was not different from venous samples (point estimated difference 0.52%, P = 0.181). When comparing the three reference methods, median ARD was also not different over the full glycemic range (venous 9.0% [n = 681], arterialized-venous 8.3% [n = 684], and capillary 8.1% [n = 205], P = 0.216), nor over the separate glucose ranges. Arterialization was successful (PO2 venous 5.4 kPa vs. arterialized-venous 8.9 kPa, P reference measurements did not significantly impact CGM accuracy. Venous reference seems preferable due to its ease of operation.

  12. Development of solid state reference electrodes and pH sensors for monitoring nuclear reactor cooling water systems

    International Nuclear Information System (INIS)

    Hettiarachchi, S.; Makela, K.; Macdonald, D.D.

    1991-01-01

    The growing interest in the electrochemical and corrosion behavior of structural alloys in high temperature aqueous systems has stimulated research in the design and testing of reliable reference electrodes and pH sensors for use in such environments. External reference electrodes have been successfully used in the recent years in high temperature aqueous environments, although their long-term stability is questionable. On the other hand, more reliable pH sensors have been developed by various workers for high temperature applications, the major drawback being their sensitivity to dissolved hydrogen, oxygen and other redox species. This paper describes the development of both solid-state reference electrodes and yttria-stabilized zirconia (YSZ) pH sensors for application in high temperature aqueous systems. (author)

  13. Nuclear emergency response exercises and decision support systems - integrating domestic experience with international reference systems

    International Nuclear Information System (INIS)

    Slavnicu, D.S.; Vamanu, D.V.; Gheorghiu, D.; Acasandrei, V.T.; Slavnicu, E.

    2010-01-01

    The paper glosses on the experience of a research-oriented team routinely involved in emergency preparedness and response management activities, with the assimilation, implementation, and application of decision support systems (DSS) of continental reference in Europe, and the development of supportive, domestic radiological assessment tools. Two exemplary nuclear alert exercises are discussed, along with solutions that emerged during drill planning and execution, to make decision support tools of various origins and strength to work synergistically and complement each other. (authors)

  14. Reference reactor module for NASA's lunar surface fission power system

    International Nuclear Information System (INIS)

    Poston, David I.; Kapernick, Richard J.; Dixon, David D.; Werner, James; Qualls, Louis; Radel, Ross

    2009-01-01

    Surface fission power systems on the Moon and Mars may provide the first US application of fission reactor technology in space since 1965. The Affordable Fission Surface Power System (AFSPS) study was completed by NASA/DOE to determine the cost of a modest performance, low-technical risk surface power system. The AFSPS concept is now being further developed within the Fission Surface Power (FSP) Project, which is a near-term technology program to demonstrate system-level TRL-6 by 2013. This paper describes the reference FSP reactor module concept, which is designed to provide a net power of 40 kWe for 8 years on the lunar surface; note, the system has been designed with technologies that are fully compatible with a Martian surface application. The reactor concept uses stainless-steel based. UO 2 -fueled, pumped-NaK fission reactor coupled to free-piston Stirling converters. The reactor shielding approach utilizes both in-situ and launched shielding to keep the dose to astronauts much lower than the natural background radiation on the lunar surface. The ultimate goal of this work is to provide a 'workhorse' power system that NASA can utilize in near-term and future Lunar and Martian mission architectures, with the eventual capability to evolve to very high power, low mass systems, for either surface, deep space, and/or orbital missions.

  15. Initial testing of a neutron activation analysis system by analysing standard reference materials

    International Nuclear Information System (INIS)

    Suhaimi Hamzah; Roslan Idris; Abdul Khalik Haji Wood; Che Seman Mahmood; Abdul Rahim Mohamad Noor.

    1983-01-01

    This paper describes the data acquisition and processing system in our laboratories (ND6600), the methods of activation analysis and the results obtained from our analysis of IAEA standard reference material (SL-l lake sediments and NBS coal ash 1632a). These standards were analysed in order to check the capability of the system, which was designed in such a way as to enable the user to independently collect and process data from multiple radiation detectors. (author)

  16. System for effluent treatment with particular reference to the reuse of the water

    Energy Technology Data Exchange (ETDEWEB)

    Rolke, O.E.

    1979-01-01

    A system for effluent treatment with particular reference to the reuse of the water consisted of biological treatment, flocculation, filtration, activated carbon adsorption and ion exchange. Such a multistage system is needed to treat wastewaters from coal gasification and coke-oven plants since the effluents, derived from cooling water for scrubbers, waste heat boilers, and heat exchangers, contains high levels of phenols, fatty acids, ammonia, suspended tar oil, and coal particles. A pilot plant, which has been built based on the system, will produce water of sufficient quality for reuse as cooling water. It is hoped that cooling systems for coal gasification plants can be 90% closed circuit.

  17. Development of the Korean Reference Vertical Disposal System Concept for Spent Fuels

    International Nuclear Information System (INIS)

    Lee, J.Y.; Cho, D.K.; Kim, S.G.; Choi, H.J.; Choi, J.W.; Hahn, P.S.

    2006-01-01

    The development of a deep geologic disposal system for the spent fuel from nuclear power plants has been carried out since this program was launched at 1997 in Korea. In ' this paper, a pre-conceptual design of the Korean Reference HLW Vertical disposal System (KRS-V1) is presented. Though no site for the underground repository has yet been specified in Korea, a generic site with granitic rock is considered for reference HLW repository design. Depth of the repository is assumed to be 500 meters. The repository consists of the disposal area, technical rooms with four shafts to connect them to the ground level in the controlled area and technical rooms with an access tunnel and three shafts to connect them to the ground level in the uncontrolled area. Disposal area consists of disposal tunnels, panel tunnels and a central tunnel. The repository will be excavated, operated and backfilled in several phases including an Underground Research Laboratory (URL) phase. The result of this preliminary conceptual design will be used for an evaluation of the feasibility, analyses of the long term safety, information for public communication and a cost estimation etc. (authors)

  18. Accuracy of cystatin C for the detection of abnormal renal function in children undergoing chemotherapy for malignancy: a systematic review using individual patient data.

    Science.gov (United States)

    Whiting, Penny; Birnie, Kate; Sterne, Jonathan A C; Jameson, Catherine; Skinner, Rod; Phillips, Bob

    2018-05-01

    We conducted a systematic review and individual patient data (IPD) meta-analysis to examine the utility of cystatin C for evaluation of glomerular function in children with cancer. Eligible studies evaluated the accuracy of cystatin C for detecting poor renal function in children undergoing chemotherapy. Study quality was assessed using QUADAS-2. Authors of four studies shared IPD. We calculated the correlation between log cystatin C and GFR stratified by study and measure of cystatin C. We dichotomized the reference standard at GFR 80 ml/min/1.73m 2 and stratified cystatin C at 1 mg/l, to calculate sensitivity and specificity in each study and according to age group (0-4, 5-12, and ≥ 13 years). In sensitivity analyses, we investigated different GFR and cystatin C cut points. We used logistic regression to estimate the association of impaired renal function with log cystatin C and quantified diagnostic accuracy using the area under the ROC curve (AUC). Six studies, which used different test and reference standard thresholds, suggested that cystatin C has the potential to monitor renal function in children undergoing chemotherapy for malignancy. IPD data (504 samples, 209 children) showed that cystatin C has poor sensitivity (63%) and moderate specificity (89%), although use of a GFR cut point of C has better diagnostic accuracy than creatinine as a test for glomerular dysfunction in young people undergoing treatment for cancer. Diagnostic accuracy is not sufficient for it to replace current reference standards for predicting clinically relevant impairments that may alter dosing of important nephrotoxic agents.

  19. A Practical Method for Implementing an Attitude and Heading Reference System

    Directory of Open Access Journals (Sweden)

    Rodrigo Munguía

    2014-04-01

    Full Text Available This paper describes a practical and reliable algorithm for implementing an Attitude and Heading Reference System (AHRS. This kind of system is essential for real time vehicle navigation, guidance and control applications. When low cost sensors are used, efficient and robust algorithms are required for performance to be acceptable. The proposed method is based on an Extended Kalman Filter (EKF in a direct configuration. In this case, the filter is explicitly derived from both the kinematic and error models. The selection of this kind of EKF configuration can help in ensuring a tight integration of the method for its use in filter-based localization and mapping systems in autonomous vehicles. Experiments with real data show that the proposed method is able to maintain an accurate and drift-free attitude and heading estimation. An additional result is to show that there is no ostensible reason for preferring that the filter have an indirect configuration over a direct configuration for implementing an AHRS system.

  20. Antiplatelet and anticoagulation regimen in patients with mechanical valve undergoing PCI - State-of-the-art review.

    Science.gov (United States)

    Gajanana, Deepakraj; Rogers, Toby; Iantorno, Micaela; Buchanan, Kyle D; Ben-Dor, Itsik; Pichard, Augusto D; Satler, Lowell F; Torguson, Rebecca; Okubagzi, Petros G; Waksman, Ron

    2018-04-02

    A common clinical dilemma regarding treatment of patients with a mechanical valve is the need for concomitant antiplatelet therapy for a variety of reasons, referred to as triple therapy. Triple therapy is when a patient is prescribed aspirin, a P2Y12 antagonist, and an oral anticoagulant. Based on the totality of the available evidence, best practice in 2017 for patients with mechanical valves undergoing percutaneous coronary intervention (PCI) is unclear. Furthermore, the optimal duration of dual antiplatelet therapy after PCI is evolving. With better valve designs that are less thrombogenic, the thromboembolic risks can be reduced at a lower international normalized ratio target, thus decreasing the bleeding risk. This review will offer an in-depth survey of current guidelines, current evidence, suggested approach for PCI in this cohort, and future studies regarding mechanical valve patients undergoing PCI. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Patients' knowledge and attitude towards therapeutic reference pricing system in Slovenia.

    Science.gov (United States)

    Marđetko, Nika; Kos, Mitja

    2016-10-01

    Background The therapeutic reference pricing (TRP) in Slovenia was implemented for proton pump inhibitors in 2013 and for angiotensin-converting enzyme inhibitors and lipid-lowering medicines in 2014. Objective The study aimed to assess patients' knowledge and attitude towards the TRP system. Moreover, the patients' willingness to pay was evaluated for patients who rejected the substitution of a current medicine within a therapeutic class by the reference medicine for which no co-payment is needed. Setting Invitation of patients to participate in a survey and filling in the first part of the questionnaire was run in the community pharmacies in Slovenia. The second part of the questionnaire was filled in at patients' home. Method A representative sample of 676 patients that had been prescribed at least one medicine from the three therapeutic classes was surveyed. The survey was carried out from 15th May to 15th June 2014 in 40 community pharmacies with the help of the pharmacists, who filled in the first part of the questionnaire in the presence of the patients. The second part of the questionnaire was filled in by 475 patients at home and returned by prepaid mail. Main outcome measure Patients' knowledge of and attitude to the TRP system implemented into Slovenian health care practice. Results Most of the statements describing patient' rights and duties within the TRP system were known by approximately 50 % of the patients. Patients were inhomogeneous in their view about the necessity and benefits of the TRP system, most of them regarded it as an unnecessary burden. Among 50.4 % of the patients who were required to copay for their medicine, 46.7 % accepted and 3.7 % rejected co-payment. The average co-payment was € 6.92, while the expressed average willingness to co-pay was € 10.4 per 3 months of therapy. Conclusion Our results indicate that the implementation of the TRP system and potential upgrades represent a significant challenge for the patients.

  2. Effects of perceived educational support on usage of an internet nursing reference center.

    Science.gov (United States)

    Marshall, Brenda L; Sabbagh, Lia

    2015-04-01

    The need for evidence-based practice in nursing is well established; however, the efficacy of providing online research resources to nurses delivering care at the bedside has yet to undergo empirical testing. This study evaluated the impact of minimal educational support by a nurse researcher on nurses' usage of a hospital-based online nursing reference center. This randomized, comparison group design feasibility study was conducted at a suburban medical center. Real-time RN usage of an online nursing reference center was collected over 10 months (August to May), with the comparative intervention occurring for seven of the 10 months (September to March). Independent samples t tests and analysis of variance demonstrated that nurses receiving weekly or biweekly visits from an educator had significantly higher usage of the reference center. Nurses who received minimal educational support through weekly and biweekly brief, verbally supportive visits from a nurse researcher were significantly higher users of the online nurse reference center than those receiving in-services only. Copyright 2015, SLACK Incorporated.

  3. Test reference years - meteorological bases for the technical simulation of heating systems and air-conditioning systems

    International Nuclear Information System (INIS)

    Perl, J.

    1991-01-01

    For the FRG (western part) for 12 regions with different climate test reference years (TRY) have been established. The TRYs are used for the simulation of the thermal behaviour of buildings, of the operation of heating and space avc systems, lighting control, solar plants as well as of comparable technical systems. A TRY is a collection of hourly data of important meterological parameters over a whole year. The TRYs include 14 meteorological parameters for temperature, humidity, wind, short- and long-wave radiation, atmospheric pressure, precipitation and description of the weather at that time. A TRY is to correspond to the characteristic weather conditions of the TRY region. (orig.) [de

  4. Venous, Arterialized-Venous, or Capillary Glucose Reference Measurements for the Accuracy Assessment of a Continuous Glucose Monitoring System

    NARCIS (Netherlands)

    Kropff, Jort; van Steen, Sigrid C.; deGraaff, Peter; Chan, Man W.; van Amstel, Rombout B. E.; DeVries, J. Hans

    2017-01-01

    Background: Different reference methods are used for the accuracy assessment of continuous glucose monitoring (CGM) systems. The effect of using venous, arterialized-venous, or capillary reference measurements on CGM accuracy is unclear. Methods: We evaluated 21 individuals with type 1 diabetes

  5. A reference system for the measurement of low-strength magnetic flux density

    International Nuclear Information System (INIS)

    Fiorillo, F.; Durin, G.F.; Rocchino, L.

    2006-01-01

    Magnetic flux density standards traceable to the SI units have been developed at IEN-INRIM, by which dissemination for general measurement and testing activities can be pursued. The reference system covers a range of values extending from μ 0 H∼1T to μ 0 H∼10μT and is centered on the use of NMR magnetometers, calibrated coils, and stable current sources. The relative measuring uncertainty of the system is shown to increases with decreasing the field strength value and it is estimated to range between a few 10 -6 and some 10 -3

  6. Memory systems interaction in the pigeon: working and reference memory.

    Science.gov (United States)

    Roberts, William A; Strang, Caroline; Macpherson, Krista

    2015-04-01

    Pigeons' performance on a working memory task, symbolic delayed matching-to-sample, was used to examine the interaction between working memory and reference memory. Reference memory was established by training pigeons to discriminate between the comparison cues used in delayed matching as S+ and S- stimuli. Delayed matching retention tests then measured accuracy when working and reference memory were congruent and incongruent. In 4 experiments, it was shown that the interaction between working and reference memory is reciprocal: Strengthening either type of memory leads to a decrease in the influence of the other type of memory. A process dissociation procedure analysis of the data from Experiment 4 showed independence of working and reference memory, and a model of working memory and reference memory interaction was shown to predict the findings reported in the 4 experiments. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

  7. Flow confirmation study for central venous port in oncologic outpatient undergoing chemotherapy: Evaluation of suspected system-related mechanical complications

    Energy Technology Data Exchange (ETDEWEB)

    Sofue, Keitaro, E-mail: ksofue@ncc.go.jp [Divisions of Diagnostic Radiology, National Cancer Center Hospital (Japan); Department of Radiology, Kobe University, Graduate School of Medicine (Japan); Arai, Yasuaki; Takeuchi, Yoshito [Divisions of Diagnostic Radiology, National Cancer Center Hospital (Japan); Sugimura, Kazuro [Department of Radiology, Kobe University, Graduate School of Medicine (Japan)

    2013-11-01

    Purpose: To evaluate the efficacy and outcome of a flow confirmation study (FCS) in oncologic outpatients undergoing chemotherapy suspected of a central venous port (CVP) system-related mechanical complication. Materials and methods: A total of 66 patients (27 men, 39 women; mean age, 60 years) received FCS for the following reasons: prolonged infusion time during chemotherapy (n = 32), inability to inject saline fluid (n = 15), lateral neck and/or back pain (n = 6), subcutaneous extravasation of anticancer drug (n = 5), arm swelling (n = 4), and inability to puncture the port (n = 4). FCS consisted of examining the position of CVP, potential secondary shifts or fractures, and integrity of the system using contrast material through the port. Results: Of the 66 patients, 43 had an abnormal finding uncovered by FCS. The most frequent abnormal findings was catheter kinking (n = 22). Explantation and reimplantation of the CVP system was required in 21 of the 66 patients. Remaining 45 patients were able continue using the CVP system after the FCS without any system malfunction. Conclusion: FCS was effective for evaluating CVP system-related mechanical complications and was useful for deciding whether CVP system explantation and reimplantation was required.

  8. Flow confirmation study for central venous port in oncologic outpatient undergoing chemotherapy: Evaluation of suspected system-related mechanical complications

    International Nuclear Information System (INIS)

    Sofue, Keitaro; Arai, Yasuaki; Takeuchi, Yoshito; Sugimura, Kazuro

    2013-01-01

    Purpose: To evaluate the efficacy and outcome of a flow confirmation study (FCS) in oncologic outpatients undergoing chemotherapy suspected of a central venous port (CVP) system-related mechanical complication. Materials and methods: A total of 66 patients (27 men, 39 women; mean age, 60 years) received FCS for the following reasons: prolonged infusion time during chemotherapy (n = 32), inability to inject saline fluid (n = 15), lateral neck and/or back pain (n = 6), subcutaneous extravasation of anticancer drug (n = 5), arm swelling (n = 4), and inability to puncture the port (n = 4). FCS consisted of examining the position of CVP, potential secondary shifts or fractures, and integrity of the system using contrast material through the port. Results: Of the 66 patients, 43 had an abnormal finding uncovered by FCS. The most frequent abnormal findings was catheter kinking (n = 22). Explantation and reimplantation of the CVP system was required in 21 of the 66 patients. Remaining 45 patients were able continue using the CVP system after the FCS without any system malfunction. Conclusion: FCS was effective for evaluating CVP system-related mechanical complications and was useful for deciding whether CVP system explantation and reimplantation was required

  9. Pre-authorization processes have no effect on patients undergoing knee MRI in a pediatric setting when evaluated by specialists

    Energy Technology Data Exchange (ETDEWEB)

    Pierce, Drew; Kan, J.H.; Bisset, George S. [Texas Children' s Hospital, Department of Radiology, Houston, TX (United States); May, Megan [Texas Children' s Hospital, Department of Sports Medicine, Houston, TX (United States)

    2017-02-15

    Pre-authorization processes are often used by medical insurance companies to reduce costs by managing the utilization of advanced diagnostic imaging, and their impact on patient care is unclear. The purpose of our study is to determine if a pre-authorization process increases the rate of surgically significant abnormal knee MRI and surgical referrals compared with patients referred from pediatric orthopedic specialists who do not undergo a pre-authorization process. A retrospective study was performed; 124 patients were identified who were referred for knee MRI by a pediatric orthopedist. The study population included patients who underwent an insurance pre-authorization process and the control group consisted of those who did not. The results of the MRI and whether they were deemed surgically significant, in addition to surgical referral, were recorded and compared. The study and control groups showed no statistically significant difference in outcome with regard to surgically significant findings on MRI (p = 0.92) or whether the patient required surgery (p = 0.6). In this population, there is no difference in the likelihood of an abnormal knee MRI demonstrating surgically significant findings or referral to surgery in patients who did and those who did not undergo an insurance pre-authorization process when patients are referred from a pediatric orthopedic specialist. The insurance pre-authorization process does not appear to have an impact on patient diagnosis and treatment and may unnecessarily add bureaucracy and costs. (orig.)

  10. Coagulation profile in patients undergoing video-assisted thoracoscopic lobectomy: A randomized, controlled trial.

    Directory of Open Access Journals (Sweden)

    Thomas Decker Christensen

    Full Text Available Knowledge about the impact of Low-Molecular-Weight Heparin (LMWH on the coagulation system in patients undergoing minimal invasive lung cancer surgery is sparse. The aim of this study was to assess the effect of LMWH on the coagulation system in patients undergoing Video-Assisted Thoracoscopic Surgery (VATS lobectomy for primary lung cancer.Sixty-three patients diagnosed with primary lung cancer undergoing VATS lobectomy were randomized to either subcutaneous injection with dalteparin (Fragmin® 5000 IE once daily or no intervention. Coagulation was assessed pre-, peri-, and the first two days postoperatively by standard coagulation blood test, thromboelastometry (ROTEM® and thrombin generation.Patients undergoing potential curative surgery for lung cancer were not hypercoagulable preoperatively. There was no statistically significant difference in the majority of the assessed coagulation parameters after LMWH, except that the no intervention group had a higher peak thrombin and a shorter INTEM clotting time on the first postoperative day and a lower fibrinogen level on the second postoperative day. A lower level of fibrin d-dimer in the LMWH group was found on the 1. and 2.postoperative day, although not statistical significant. No differences were found between the two groups in the amount of bleeding or number of thromboembolic events.Use of LMWH administered once daily as thromboprophylaxis did not alter the coagulation profile per se. As the present study primarily evaluated biochemical endpoints, further studies using clinical endpoints are needed in regards of an optimized thromboprophylaxis approach.

  11. Global Reference Tables for Management Information Systems

    Data.gov (United States)

    Social Security Administration — This database is a collection of reference tables that store common information used throughout SSA. These tables standardize code structures and code usage of SSA...

  12. 1-GWh diurnal load-leveling superconducting magnetic energy storage system reference design

    International Nuclear Information System (INIS)

    Hassenzahl, W.V.; Rogers, J.D.

    1979-01-01

    A point reference design has been completed for a 1-GWh Superconducting Magnetic Energy Storage system. The system is for electric utility dirunal load leveling; however, such a device will function to meet much faster power demands including dynamic stabilization. The study has explored several concepts of design not previously considered in the same detail as treated here. Because the study is for a point design, optimization in all respects is not complete. The study examines aspects of the coil design; superconductor supported off of the dewar shell; the dewar shell, its configuration and stresses; the underground excavation and related construction for holding the superconducting coil and its dewar; the helium refrigeration system; the electrical converter system; the vacuum system; the guard coil; and the costs. The report is a condensation of the more comprehensive study which is in the process of being printed

  13. Dental consultation in patients planned for/undergoing/post radiation therapy for head and neck cancers: a questionnaire-based survey.

    Science.gov (United States)

    Mainali, Apeksha; Sumanth, K N; Ongole, Ravikiran; Denny, Ceena

    2011-01-01

    Mouth and pharyngeal cancers account for approximately 6% of cancers worldwide. Radiotherapy is one of the means of treatment of head and neck cancer. Consultation with a dental team experienced in caring for patients undergoing treatment for head and neck cancer will improve the quality of life of such patients. To evaluate the attitude of oncologists toward dental consultation to patients planning for/prior to/undergoing/post radiation therapy for head and neck cancers and to evaluate the number of radiation oncologists who encounter oral complaints and consider worth referring to a dentist. A questionnaire-based study was carried out following mailing of covering letter and self-administered questionnaire comprising 11 items, to 25 radiation oncology centers selected in India based on convenient sampling. Out of the 25 centers, we received response from 20 centers with 60 completely filled questionnaires. Five centers did not respond for further correspondences. The study indicated a need for awareness and education among radiation oncologists regarding dental consultation in patients planned/undergoing /post radiation therapy for head and neck cancer.

  14. Flurbiprofen Axetil Enhances Analgesic Effects of Sufentanil and Attenuates Postoperative Emergence Agitation and Systemic Proinflammation in Patients Undergoing Tangential Excision Surgery

    Directory of Open Access Journals (Sweden)

    Wujun Geng

    2015-01-01

    Full Text Available Objective. Our present study tested whether flurbiprofen axetil could reduce perioperative sufentanil consumption and provide postoperative analgesia with decrease in emergency agitation and systemic proinflammatory cytokines release. Methods. Ninety patients undergoing tangential excision surgery were randomly assigned to three groups: (1 preoperative dose of 100 mg flurbiprofen axetil and a postoperative dose of 2 μg/kg sufentanil and 10 mL placebo by patient-controlled analgesia (PCA pump, (2 preoperative dose of 100 mg flurbiprofen axetil and a postoperative dose of 2 μg/kg sufentanil and 100 mg flurbiprofen axetil by PCA pump, and (3 10 mL placebo and a postoperative dose of 2 μg/kg sufentanil and 10 mL placebo by PCA pump. Results. Preoperative administration of flurbiprofen axetil decreased postoperative tramadol consumption and the visual analog scale at 4, 6, 12, and 24 h after surgery, which were further decreased by postoperative administration of flurbiprofen axetil. Furthermore, flurbiprofen axetil attenuated emergency agitation score and Ramsay score at 0, 5, and 10 min after extubation and reduced the TNF-α and interleukin- (IL- 6 levels at 24 and 48 h after the operation. Conclusion. Flurbiprofen axetil enhances analgesic effects of sufentanil and attenuates emergence agitation and systemic proinflammation in patients undergoing tangential excision surgery.

  15. Flurbiprofen Axetil Enhances Analgesic Effects of Sufentanil and Attenuates Postoperative Emergence Agitation and Systemic Proinflammation in Patients Undergoing Tangential Excision Surgery.

    Science.gov (United States)

    Geng, Wujun; Hong, Wandong; Wang, Junlu; Dai, Qinxue; Mo, Yunchang; Shi, Kejian; Sun, Jiehao; Qin, Jinling; Li, Mei; Tang, Hongli

    2015-01-01

    Our present study tested whether flurbiprofen axetil could reduce perioperative sufentanil consumption and provide postoperative analgesia with decrease in emergency agitation and systemic proinflammatory cytokines release. Ninety patients undergoing tangential excision surgery were randomly assigned to three groups: (1) preoperative dose of 100 mg flurbiprofen axetil and a postoperative dose of 2 μg/kg sufentanil and 10 mL placebo by patient-controlled analgesia (PCA) pump, (2) preoperative dose of 100 mg flurbiprofen axetil and a postoperative dose of 2 μg/kg sufentanil and 100 mg flurbiprofen axetil by PCA pump, and (3) 10 mL placebo and a postoperative dose of 2 μg/kg sufentanil and 10 mL placebo by PCA pump. Preoperative administration of flurbiprofen axetil decreased postoperative tramadol consumption and the visual analog scale at 4, 6, 12, and 24 h after surgery, which were further decreased by postoperative administration of flurbiprofen axetil. Furthermore, flurbiprofen axetil attenuated emergency agitation score and Ramsay score at 0, 5, and 10 min after extubation and reduced the TNF-α and interleukin- (IL-) 6 levels at 24 and 48 h after the operation. Flurbiprofen axetil enhances analgesic effects of sufentanil and attenuates emergence agitation and systemic proinflammation in patients undergoing tangential excision surgery.

  16. Hematoimmunological state of patients with inoperable cervical cancer undergoing multimodality treatment

    International Nuclear Information System (INIS)

    Nikiforova, N.A.; Sorochan, P.P.; Revenkova, S.Yi.; Moskalenko, Yi.P.

    2005-01-01

    Hematological parameters and immunity state were studied in 53 patients with inoperable cervical cancer undergoing radiochemotherapy. It is reasonable use prolonged 5-FU infusions during chemoradiation treatment from 6 p.m. to 6 a.m. with the purpose to minimize the complications in the homeostasis system

  17. The System For Co-Reference Resolution For Slovenian Texts Analysis and Possibilities of its Use

    Directory of Open Access Journals (Sweden)

    Peter Holozan

    2015-10-01

    Full Text Available Co-reference resolution is an important part of language technologies, but has not yet been developed for Slovenian. There are various types of co-references and the paper focuses on anaphora resolution of personal pronouns. Seven methods, used in combination, were used; the most important one is based on activation. First results are promising, but for more extensive evaluation, Slovenian corpus with marked examples is needed. Co-reference resolution was used in the question answering system Crammer, which can, as a result, answer more questions than before, because it can replace personal pronouns. At the same time, some other improvement were added to Crammer, e.g. answering to individual words and phrases and answering to declarative sentences. Added was also generation of long answers to questions with interrogative particles. Co-reference resolution also improved working of Presis machine translation, especially for determining of gender of pronouns and for disambiguation of attributive subordinate clauses.

  18. Overview of external reference pricing systems in Europe.

    Science.gov (United States)

    Rémuzat, Cécile; Urbinati, Duccio; Mzoughi, Olfa; El Hammi, Emna; Belgaied, Wael; Toumi, Mondher

    2015-01-01

    External reference pricing (ERP) is a price regulation tool widely used by policy makers in the European Union (EU) Member States (MS) to contain drug cost, although in theory, it may contribute to modulate prices up and down. The objective of this article was to summarise and discuss the main findings of part of a large project conducted for the European Commission ('External reference pricing of medicinal products: simulation-based considerations for cross-country coordination'; see www.ec.europa.eu/health/healthcare/docs/erp_reimbursement_medicinal_products_en.pdf) that aimed to provide an overview of ERP systems, both on processes and potential issues in 31 European countries (28 EU MS, Iceland, Norway, and Switzerland). A systematic structured literature review was conducted to identify and characterise the use of ERP in the selected countries, to describe its impact on the prices of pharmaceuticals, and to discuss the possible cross-country coordination issues in EU MS. This research was complemented with a consultation of competent authorities' and international organisations' representatives to address the main issues or uncertainties identified through the literature review. All selected countries applied ERP, except the United Kingdom and Sweden. Twenty-three countries used ERP as the main systematic criterion for pricing. In the majority of European countries, ERP was based on legislated pricing rules with different levels of accuracy. ERP was applied either for all marketed drugs or for specific categories of medicines; it was mainly used for publicly reimbursed medicines. The number of reference countries included in the basket varied from 1 to 31. There was a great variation in the calculation methods used to compute the price; 15 countries used the average price, 7 countries used the lowest price, and 7 countries used other calculation methods. Reported limitations of ERP application included the lack of reliable sources of price information, price

  19. Balinese Frame of Reference

    Directory of Open Access Journals (Sweden)

    I Nyoman Aryawibawa

    2016-04-01

    Full Text Available Abstract: Balinese Frame of Reference. Wassmann and Dasen (1998 did a study on the acquisition of Balinese frames of reference. They pointed out that, in addition to the dominant use of absolute system, the use of relative system was also observed. This article aims at verifying Wassmann and Dasen’ study. Employing monolingual Balinese speakers and using linguistic and non-linguistic tasks, Aryawibawa (2010, 2012, 2015 showed that Balinese subjects used an absolute system dominantly in responding the two tasks, e.g. The man is north/south/east/west of the car. Unlike Wassmann and Dasen’s results, no relative system was used by the subjects in solving the tasks. Instead of the relative system, an intrinsic system was also observed in this study, even though it was unfrequent. The article concludes that the absolute system was dominantly employed by Balinese speakers in describing spatial relations in Balinese. The use of the system seems to affect their cognitive functions.

  20. Top-Down Enterprise Application Integration with Reference Models

    Directory of Open Access Journals (Sweden)

    Willem-Jan van den Heuvel

    2000-11-01

    Full Text Available For Enterprise Resource Planning (ERP systems such as SAP R/3 or IBM SanFrancisco, the tailoring of reference models for customizing the ERP systems to specific organizational contexts is an established approach. In this paper, we present a methodology that uses such reference models as a starting point for a top-down integration of enterprise applications. The re-engineered models of legacy systems are individually linked via cross-mapping specifications to the forward-engineered reference model's specification. The actual linking of reference and legacy models is done with a methodology for connecting (new business objects with (old legacy systems.

  1. A reference sample for investigating the stability of the imaging system of x-ray computed tomography

    International Nuclear Information System (INIS)

    Sun, Wenjuan; Brown, Stephen; Flay, Nadia; McCarthy, Michael; McBride, John

    2016-01-01

    The use of x-ray computed tomography for dimensional measurements associated with engineering applications has flourished in recent years. However, error sources associated with the technology are not well understood. In this paper, a novel two-sphere reference sample has been developed and used to investigate the stability of the imaging system that consists of an x-ray tube and a detector. In contrast with other research work reported, this work considered relative positional variation along the x -, y - and z -axes. This sample is a significant improvement over the one sphere sample proposed previously, which can only be used to observe the stability of the imaging system along x - and y -axes. Temperature variations of different parts of the system have been monitored and the relationship between temperature variations and x-ray image stability has been studied. Other effects that may also influence the stability of the imaging system have been discussed. The proposed reference sample and testing method are transferable to other types of x-ray computed tomography systems, for example, systems with transmission targets and systems with sub-micrometre focal spots. (paper)

  2. National Health and Nutrition Examination Survey whole-body dual-energy X-ray absorptiometry reference data for GE Lunar systems.

    Science.gov (United States)

    Fan, Bo; Shepherd, John A; Levine, Michael A; Steinberg, Dee; Wacker, Wynn; Barden, Howard S; Ergun, David; Wu, Xin P

    2014-01-01

    The National Health and Nutrition Examination Survey (NHANES 1999-2004) includes adult and pediatric comparisons for total body bone and body composition results. Because dual-energy x-ray absorptiometry (DXA) measurements from different manufacturers are not standardized, NHANES reference values currently are applicable only to a single make and model of Hologic DXA system. The purpose of this study was to derive body composition reference curves for GE Healthcare Lunar DXA systems. Published values from the NHANES 1999-2004 survey were acquired from the Centers for Disease Control and Prevention website. Using previously reported cross-calibration equations between Hologic and GE-Lunar, we converted the total body and regional bone and soft-tissue measurements from NHANES 1999-2004 to GE-Lunar values. The LMS (LmsChartMaker Pro Version 3.5) curve fitting method was used to generate GE-Lunar reference curves. Separate curves were generated for each sex and ethnicity. The reference curves were also divided into pediatric (≤20 years old) and adult (>20 years old) groups. Adult reference curves were derived as a function of age. Additional relationships of pediatric DXA values were derived as a function of height, lean mass, and bone area. Robustness was tested between Hologic and GE-Lunar Z-score values. The NHANES 1999-2004 survey included a sample of 20,672 participants' (9630 female) DXA scans. A total of 8056 participants were younger than 20 yr and were included in the pediatric reference data set. Participants enrolled in the study who weighed more than 136 kg (over scanner table limit) were excluded. The average Z-scores comparing the new GE-Lunar reference curves are close to zero, and the standard deviation of the Z-scores are close to one for all variables. As expected, all measurements on the GE-Lunar reference curves for participants younger than 20 yr increase monotonically with age. In the adult population, most of the curves are constant at younger

  3. Reference design of the power supply system for the resistive-wall-mode control in JT-60SA

    Energy Technology Data Exchange (ETDEWEB)

    Ferro, Alberto, E-mail: alberto.ferro@igi.cnr.it [Consorzio RFX, C.so Stati Uniti 4, 35127 Padova (Italy); Gaio, Elena [Consorzio RFX, C.so Stati Uniti 4, 35127 Padova (Italy); Novello, Luca [Fusion for Energy, Broader Development of Fusion Department, Boltzmannstr 2, 85748 Garching (Germany); Matsukawa, Makoto; Shimada, Katsuhiro; Kawamata, Yoichi; Takechi, Manabu [Japan Atomic Energy Agency, Naka Fusion Institute, 801-1 Mukoyama, Naka, Ibaraki 311-019 (Japan)

    2015-10-15

    Highlights: • In JT-60SA, a power supply system (RWM-PS) will feed 18 coils to control the RWMs. • One power amplifier per coil will follow an arbitrary real-time reference. • Very fast dynamics is required (current bandwidth: 3 kHz; latency: 50 μs). • The requirements of the RWM-PS are updated and design solutions discussed. • The reference design of the RWM-PS is based on H-bridges operated at 20 – 30 kHz. - Abstract: The mission of JT-60SA, the satellite Tokamak under construction in Naka (Japan), includes the attainment of steady-state high-beta plasmas. For this purpose, an active control system based on 18 in-vessel sector coils (SC) is foreseen to suppress the resistive wall modes (RWM). Each coil will be independently fed by a dedicated converter, rated for 300 A and 240 V, which has to produce the required current/voltage following in real time the reference provided by the JT-60SA MHD Controller. To minimize the current rating, these converters shall be sufficiently fast to avoid an excessive growth of the RWM. This requires a very high dynamic performance, largely beyond that of standard industrial applications. This paper firstly reports the latest results of the studies on the requirements of the RWM active control system. Then, the reference design of the power supply system is presented, including the ac/dc conversion stage, the fast converters and the control section. The advantages of the proposed scheme are discussed and the main electrical parameters are presented.

  4. Radiation assessment to paediatric with F-18-FDG undergo whole-body PET/CT examination

    Energy Technology Data Exchange (ETDEWEB)

    Dhalisa, H., E-mail: dhalisa82@gmail.com; Rafidah, Z. [Kluster Oncology Science and Radiology, Advanced Medical Dental Institute, Universiti Sains Malaysia (USM), Bertam, Penang (Malaysia); Mohamad, A. S. [Department of Nuclear Medicine, National Cancer Institute, No 4 Jalan P7, Presint 7, Putrajaya (Malaysia)

    2016-01-22

    This study was carried out on wholebody radiation dose assessment to paediatrics patient who undergo PET/CT scanner at Institut Kanser Negara. Consist of 68 patients with varies of malignancies and epilepsy disease case covering age between 2 years to 12 years old. This is a retrospective study from 2010-2014. The use of PET/CT scanner as an advanced tool has been proven to give an extra radiation dose to the patient. It is because of the radiation exposure from the combination of both CT and PET scans rather than a single CT or PET scan. Furthermore, a study on radiation dose to paediatric patient undergoing PET/CT is rare in Malaysia. So, the aim of this study is to estimate the wholebody effective dose to paediatric patient in Malaysia. Effective dose from PET scan was calculated based on the activity of F18 FDG and dose coefficient reported in International Commission on Radiological Protection (ICRP) Publication 106. Effective dose from CT was determined using k coefficient as reported in ICRP publication 102 and Dose Length Product (DLP) value. The average effective dose from PET and CT were found to be 7.05mSv and 5.77mSv respectively. The mean wholebody effective dose received by a patient with combined PETCT examination was 12.78mSv. These results could be used as reference for dosimetry of a patient undergoing PETCT examination in Malaysia.

  5. Prevalence and clinical significance of extravascular incidental findings in patients undergoing CT cervico-cerebral angiography

    International Nuclear Information System (INIS)

    Crockett, Matthew Thomas; Murphy, Blathnaid; Smith, Jennifer; Kavanagh, Eoin Carl

    2015-01-01

    Highlights: • CT cervico-cerebral angiography (CTCCA) is a commonly performed study for assessment of vascular pathologies of head and neck. • This study assessed the prevalence, clinical significance and management of extravascular incidental findings detected on CTCCA. • This study demonstrated the presence of clinically significant incidental findings in 14% of patients undergoing CTCCA with 8% of these findings deemed to be highly significant. 19% of patients with highly clinically significant findings did not receive appropriate follow up. • A standardised method of reporting incidental findings, such as that used in this paper is suggested to aid radiologists and referring physicians in recording and communicating these findings. - Abstract: Introduction: CT cervico-cerebral angiography (CTCCA) is now the first line diagnostic imaging modality for the majority of vascular pathologies of the head and neck with diagnostic value comparable to or better than traditional angiographic techniques. The aim of this study was to assess the prevalence, clinical significance and management of extravascular incidental findings detected on CTCCA. Materials and methods: A retrospective review of the CTCCA reports of 302 consecutive patients from 2009 to 2013 was undertaken. Extravascular incidental findings were classified, according to an adaptation of the CT colonography data and reporting system (CRADS), as EV1–EV4. EV1 = no incidental findings, EV2 = clinically insignificant incidental finding, EV3 = incidental finding of intermediate clinical significance, EV4 = highly clinically significant finding. Follow up of the electronic medical records of patients with EV3 or EV4 findings was undertaken to determine subsequent management. Results: Potentially clinically significant findings were demonstrated in 14.2% of patients with 8.6% of patients having a highly clinically significant finding. 4 incidental findings were confirmed to be malignant lesions and 5

  6. Data reference and retrieval system for Richton Dome, Mississippi: annual status report for fiscal year 1982

    International Nuclear Information System (INIS)

    1983-06-01

    The Geologic Data Base for Richton Dome, Mississippi, was updated and expanded in FY 82 to support National Waste Terminal Storage characterization studies. The existing data base, consisting of references, maps, remote sensing data, and well-boring information, was inventoried to catalog the data acquired during previous studies. This catalog is maintained on Ertec's in-house computer. Bibliographies of selected documents were reviewed and commercial data bases were searched to identify additional references pertinent to future geologic characterization studies to be added to the data base. In addition to the references, selected preliminary safety analysis report sections and associated reports for nuclear generating stations, oil and gas well completion records, and US Geological Survey System 2000 hydrologic data were obtained for specific areas of Mississippi and Alabama. These additional data and references provide a comprehensive and current data base for Richton Dome

  7. Reference Models of Information Systems Constructed with the use of Technologies of Cloud Calculations

    Directory of Open Access Journals (Sweden)

    Darya Sergeevna Simonenkova

    2013-09-01

    Full Text Available The subject of the research is analysis of various models of the information system constructed with the use of technologies of cloud calculations. Analysis of models is required for constructing a new reference model which will be used for develop a security threats model.

  8. Determining the direction of a geometrical/optical reference axis in the coordinate system of a triaxial magnetometer sensor

    DEFF Research Database (Denmark)

    Primdahl, Fritz; Brauer, Peter; Merayo, José M.G.

    2002-01-01

    optical or geometrical axes in order to be able to determine the precise orientation of the magnetic coordinate axes in an external reference system. Two methods for determining a reference axis in the sensor coordinates are discussed: (1) using a triaxial coil facility to measure the sensor orientation...

  9. Setting reference targets

    International Nuclear Information System (INIS)

    Ruland, R.E.

    1997-04-01

    Reference Targets are used to represent virtual quantities like the magnetic axis of a magnet or the definition of a coordinate system. To explain the function of reference targets in the sequence of the alignment process, this paper will first briefly discuss the geometry of the trajectory design space and of the surveying space, then continue with an overview of a typical alignment process. This is followed by a discussion on magnet fiducialization. While the magnetic measurement methods to determine the magnetic centerline are only listed (they will be discussed in detail in a subsequent talk), emphasis is given to the optical/mechanical methods and to the task of transferring the centerline position to reference targets

  10. Prevention of hypothermia in patients undergoing orthotopic liver transplantation using the humigard® open surgery humidification system: a prospective randomized pilot and feasibility clinical trial.

    Science.gov (United States)

    Weinberg, Laurence; Huang, Andrew; Alban, Daniel; Jones, Robert; Story, David; McNicol, Larry; Pearce, Brett

    2017-01-23

    Perioperative thermal disturbances during orthotopic liver transplantation (OLT) are common. We hypothesized that in patients undergoing OLT the use of a humidified high flow CO 2 warming system maintains higher intraoperative temperatures when compared to standardized multimodal strategies to maintain thermoregulatory homeostasis. We performed a randomized pilot study in adult patients undergoing primary OLT. Participants were randomized to receive either open wound humidification with a high flow CO 2 warming system in addition to standard care (Humidification group) or to standard care alone (Control group). The primary end point was nasopharyngeal core temperature measured 5 min immediately prior to reperfusion of the donor liver (Stage 3 - 5 min). Secondary endpoints included intraoperative PaCO 2 , minute ventilation and the use of vasoconstrictors. Eleven patients were randomized to each group. Both groups were similar for age, body mass index, MELD, SOFA and APACHE II scores, baseline temperature, and duration of surgery. Immediately prior to reperfusion (Stage 3 - 5 min) the mean (SD) core temperature was higher in the Humidification Group compared to the Control Group: 36.0 °C (0.13) vs. 35.4 °C (0.22), p = 0.028. Repeated measured ANOVA showed that core temperatures over time during the stages of the transplant were higher in the Humidification Group compared to the Control Group (p < 0.0001). There were no significant differences in the ETCO 2 , PaCO 2 , minute ventilation, or inotropic support. The humidified high flow CO 2 warming system was superior to standardized multimodal strategies in maintaining normothermia in patients undergoing OLT. Use of the device was feasible and did not interfere with any aspects of surgery. A larger study is needed to investigate if the improved thermoregulation observed is associated with improved patient outcomes. ACTRN12616001631493 . Retrospectively registered 25 November 2016.

  11. Comparison of the TLDA with the Nanodrop and the reference Qubit system

    Energy Technology Data Exchange (ETDEWEB)

    O' Neill, M; Arthure, K; Riedel, S; McMillan, ND [Drop Technology Ltd., Tallaght Business Park, Whitestown, Dublin 24 (Ireland); McPartlin, J, E-mail: martina.oneill@droptechnology.com [Vitamin Research Unit, Department of Clinical Medicine, Sir Patrick Duns Laboratory, CPL, St. James' s Hospital, Dublin 8 (Ireland)

    2011-08-17

    The TLDA (transmitted light drop analyser) is a new microvolume UV-visible drop spectrophotometer new to the market. Assays were compared between a TLDA, NanoDrop and the Qubit system which is based on the gold standard for DNA assay, PicoGreen. The evaluation was carried out by the Trinity Biobank in St. James Hospital, Dublin on Buccal swabs and Blood samples. The data is discussed in this paper. The Qubit system is seen as the reference method in most studies as this is believed to provide more accurate results than UV absorbance methods because it distinguishes between DNA, RNA, free nucleotides, and other contaminants. The Qubit system uses fluorescent dyes to measure the concentration of the molecule of interest. The results compare both the spectrophotometric methods against the Qubit fluorescence technique.

  12. Development of picture quality monitoring system for IPTV service based on the reduced reference framework

    Science.gov (United States)

    Sugimoto, Osamu; Kawada, Ryoichi; Koike, Atsushi

    2006-01-01

    The authors developed a software-based realtime IPTV monitoring system based on Reduced Reference framework, and evaluated the proposed system. One of the quality issues of the IPTV service is the picture quality degradation caused by packet loss. The proposed system precisely estimates the PSNR of the corrupted received picture by extracting and comparing image features from transmission and receiver side. Computer simulations show that PSNR estimation with a 0.945 correlation coefficient at a data channel bitrate of 36kbps is possible using the proposed system.

  13. Development of a reference liquid scintillation cocktail

    CSIR Research Space (South Africa)

    Van Wyn Gaardt, WM

    2006-02-01

    Full Text Available A reference system that would allow national laboratories to compare their activity measurements of non-gamma-emitting radionuclides at any time is currently being developed. The system requires a non-commercial reference-liquid scintillation...

  14. Myenteric plexitis: A frequent feature in patients undergoing surgery for colonic diverticular disease.

    Science.gov (United States)

    Bassotti, Gabrio; Villanacci, Vincenzo; Sidoni, Angelo; Nascimbeni, Riccardo; Dore, Maria P; Binda, Gian A; Bandelloni, Roberto; Salemme, Marianna; Del Sordo, Rachele; Cadei, Moris; Manca, Alessandra; Bernardini, Nunzia; Maurer, Christoph A; Cathomas, Gieri

    2015-12-01

    Diverticular disease of the colon is frequent in clinical practice, and a large number of patients each year undergo surgical procedures worldwide for their symptoms. Thus, there is a need for better knowledge of the basic pathophysiologic mechanisms of this disease entity. Because patients with colonic diverticular disease have been shown to display abnormalities of the enteric nervous system, we assessed the frequency of myenteric plexitis (i.e. the infiltration of myenteric ganglions by inflammatory cells) in patients undergoing surgery for this condition. We analyzed archival resection samples from the proximal resection margins of 165 patients undergoing left hemicolectomy (60 emergency and 105 elective surgeries) for colonic diverticulitis, by histology and immunochemistry. Overall, plexitis was present in almost 40% of patients. It was subdivided into an eosinophilic (48%) and a lymphocytic (52%) subtype. Plexitis was more frequent in younger patients; and it was more frequent in those undergoing emergency surgery (50%), compared to elective (28%) surgery (p = 0.007). All the severe cases of plexitis displayed the lymphocytic subtype. In conclusion, myenteric plexitis is frequent in patients with colonic diverticular disease needing surgery, and it might be implicated in the pathogenesis of the disease.

  15. Communication: Density functional theory model for multi-reference systems based on the exact-exchange hole normalization.

    Science.gov (United States)

    Laqua, Henryk; Kussmann, Jörg; Ochsenfeld, Christian

    2018-03-28

    The correct description of multi-reference electronic ground states within Kohn-Sham density functional theory (DFT) requires an ensemble-state representation, employing fractionally occupied orbitals. However, the use of fractional orbital occupation leads to non-normalized exact-exchange holes, resulting in large fractional-spin errors for conventional approximative density functionals. In this communication, we present a simple approach to directly include the exact-exchange-hole normalization into DFT. Compared to conventional functionals, our model strongly improves the description for multi-reference systems, while preserving the accuracy in the single-reference case. We analyze the performance of our proposed method at the example of spin-averaged atoms and spin-restricted bond dissociation energy surfaces.

  16. Communication: Density functional theory model for multi-reference systems based on the exact-exchange hole normalization

    Science.gov (United States)

    Laqua, Henryk; Kussmann, Jörg; Ochsenfeld, Christian

    2018-03-01

    The correct description of multi-reference electronic ground states within Kohn-Sham density functional theory (DFT) requires an ensemble-state representation, employing fractionally occupied orbitals. However, the use of fractional orbital occupation leads to non-normalized exact-exchange holes, resulting in large fractional-spin errors for conventional approximative density functionals. In this communication, we present a simple approach to directly include the exact-exchange-hole normalization into DFT. Compared to conventional functionals, our model strongly improves the description for multi-reference systems, while preserving the accuracy in the single-reference case. We analyze the performance of our proposed method at the example of spin-averaged atoms and spin-restricted bond dissociation energy surfaces.

  17. Uvođenje novih geodetskih referentnih sistema u Bosni i Hercegovini : Introduction of a new geodetic reference systems in Bosnia and Herzegovina

    Directory of Open Access Journals (Sweden)

    Šeho Zimić

    2017-12-01

    Full Text Available The introduction of a new reference system in Bosnia and Herzegovina is not only a necessity, but an obligation imposed by the United Nations (UN and the European Union (EU. At the General Assembly on February 26, 2015, the UN has adopted a resolution titled "Global Geodetic Reference Frame for Sustainable Development - GGRF", which for the first time raise the geodetic issue as a political issue at such a high level. The resolution highlights the strong need for more precise positioning and navigation from the use of smartphones to the study of climate changes, population migrations and other scientific researches of relevance to the whole world (http://www.unggrf.org/. All this is not possible without a global exchange of geodata and a common global geodetic reference system. Through the Inspire Directive, the EU has clearly specified which coordinate and heights systems are being applied in Europe. The countries in the region have adopted the European terrestrial reference system ETRS89 as a new reference system in their legislation. Through the EUREF campaign BALKAN98 and the introduction of the Network of permanent GNSS stations Bosnia and Herzegovina has joined the famil

  18. Utility of an Australasian registry for children undergoing radiation treatment

    International Nuclear Information System (INIS)

    Ahern, Verity

    2014-01-01

    The aim of this study was to evaluate the utility of an Australasian registry ('the Registry') for children undergoing radiation treatment (RT). Children under the age of 16years who received a course of radiation between January 1997 and December 2010 and were enrolled on the Registry form the subjects of this study. A total of 2232 courses of RT were delivered, predominantly with radical intent (87%). Registrations fluctuated over time, but around one-half of children diagnosed with cancer undergo a course of RT. The most prevalent age range at time of RT was 10–15years, and the most common diagnoses were central nervous system tumours (34%) and acute lymphoblastic leukaemia (20%). The Registry provides a reflection of the patterns of care of children undergoing RT in Australia and a mechanism for determining the resources necessary to manage children by RT (human, facilities and emerging technologies, such as proton therapy). It lacks the detail to provide information on radiotherapy quality and disease outcomes which should be the subject of separate audit studies. The utility of the Registry has been hampered by its voluntary nature and varying needs for consent. Completion of registry forms is a logical requirement for inclusion in the definition of a subspecialist in paediatric radiation oncology.

  19. Pathway to 2022: The Ongoing Modernization of the United States National Spatial Reference System

    Science.gov (United States)

    Stone, W. A.; Caccamise, D.

    2017-12-01

    The National Oceanic and Atmospheric Administration's National Geodetic Survey (NGS) mission is "to define, maintain and provide access to the National Spatial Reference System (NSRS) to meet our nation's economic, social, and environmental needs." The NSRS is an assemblage of geophysical and geodetic models, tools, and data, with the most-visible components being the North American Datum of 1983 (NAD83) and the North American Vertical Datum of 1988 (NAVD88), which together provide a consistent spatial reference framework for myriad geospatial applications and positioning requirements throughout the United States. The NGS is engaged in an ongoing and comprehensive multi-year project of modernizing the NSRS, a makeover necessitated by technological developments and user accuracy requirements, all with a goal of providing a modern, accurate, accessible, and globally aligned national positioning framework exploiting the substantial power and utility of the Global Navigation Satellite System - of both today and tomorrow. The modernized NSRS will include four new-generation geometric terrestrial reference frames (replacing NAD83) and a technically unprecedented geopotential datum (replacing NAVD88), all to be released in 2022 (anticipated). This poster/presentation will describe the justification for this modernization effort and will update the status and planned evolution of the NSRS as 2022 draws ever closer. Also discussed will be recent developments, including the publication of "blueprint" documents addressing technical details of various facets of the modernized NSRS and a continued series of public Geospatial Summits. Supporting/ancillary projects such as Gravity for the Redefinition of the American Vertical Datum (GRAV-D), which will result in the generation of a highly accurate gravimetric geoid - or definitional reference surface (zero elevation) - for the future geopotential datum, and Geoid Slope Validation Surveys (GSVS), which are exploring the achievable

  20. 1-GWh diurnal load-leveling Superconducting Magnetic Energy Storage system reference design

    International Nuclear Information System (INIS)

    Rogers, J.D.; Hassenzahl, W.V.; Schermer, R.I.

    1979-09-01

    A point reference design has been completed for a 1-GWh Superconducting Magnetic Energy Storage system. The system is for electric utility diurnal load-leveling but can also function to meet much faster power demands including dynamic stabilization. This study explores several concepts of design not previously considered in the same detail as treated here. Because the study is for a point design, optimization in all respects is not complete. This report examines aspects of the coil, the superconductor supported off of the dewar shell, the dewar shell, and its configuration and stresses, the underground excavation and construction for holding the superconducting coil and its dewar, the helium refrigeration system, the electrical converter system, the vacuum system, the guard coil, and the costs. This report is divided into two major portions. The first is a general treatment of the work and the second is seven detailed technical appendices issued as separate reports. The information presented on the aluminum stabilizer for the conductor, on the excavation, and on the converter is based upon industrial studies contracted for this work

  1. Increasing innovation capability:of product-service systems through collaborative networks

    OpenAIRE

    Wallin, Johanna

    2011-01-01

    Many manufacturing industries are undergoing a transition from manufacturing of products towards integrating more services into the traditional product concepts and provide product-service systems (PSS). Development of PSS changes the focus from the product to the functionality of the product; hence it can be referred to as functional product development. PSS also puts focus on the value of the knowledge-intensive solution. This change in focus challenges the way companies innovate. When deve...

  2. Program reference schedule baseline

    International Nuclear Information System (INIS)

    1986-07-01

    This Program Reference Schedule Baseline (PRSB) provides the baseline Program-level milestones and associated schedules for the Civilian Radioactive Waste Management Program. It integrates all Program-level schedule-related activities. This schedule baseline will be used by the Director, Office of Civilian Radioactive Waste Management (OCRWM), and his staff to monitor compliance with Program objectives. Chapter 1 includes brief discussions concerning the relationship of the PRSB to the Program Reference Cost Baseline (PRCB), the Mission Plan, the Project Decision Schedule, the Total System Life Cycle Cost report, the Program Management Information System report, the Program Milestone Review, annual budget preparation, and system element plans. Chapter 2 includes the identification of all Level 0, or Program-level, milestones, while Chapter 3 presents and discusses the critical path schedules that correspond to those Level 0 milestones

  3. The University of Texas at Arlington's Virtual Reference Service: An Evaluation by the Reference Staff

    Science.gov (United States)

    Casebier, Katherine D.

    2006-01-01

    The University of Texas at Arlington's Library began using an online chat reference in 2002. The service, called Collaborative Digital Reference Service, later became "Ask a Librarian." Slightly over one year later, the library joined the University of Texas System's "Ask a Librarian" service. Both services are powered by…

  4. Multidisciplinary Management of Complicated Crown-Root Fracture of an Anterior Tooth Undergoing Apexification

    Directory of Open Access Journals (Sweden)

    Merve Mese

    2015-01-01

    Full Text Available The purpose of this case report was to present the multidisciplinary management of a subgingival crown-root fracture of a patient undergoing apexification treatment. A 12-year-old male patient was referred to the pediatric dentistry clinic with an extensive tooth fracture of the right permanent maxillary lateral incisor. Clinical and radiographic examinations revealed the presence of a complicated crown-root fracture, which had elongated to the buccal subgingival area. The dental history disclosed that the apexification procedure had been started to be performed after his first trauma experience and he had neglected his appointment. The coronal fragment was gently extracted; endodontic treatment was performed; flap surgery was performed to make the fracture line visible. The coronal fragment was reattached to the root fragment with a dual-cure luting composite. A fiber post was stabilized and the access cavity of the tooth was restored with composite resin. At the end of the 24th month, the tooth was asymptomatic, functionally, esthetically acceptable and had no periapical pathology. It is important for the patients undergoing apexification treatment to keep their appointments because of the fracture risk. Restoration of the fractured tooth by preparing retention grooves and a bonding fiber-reinforced post are effective and necessary approaches for successful management.

  5. Dental Health of Patients Undergoing Hemodialysis (A Study

    Directory of Open Access Journals (Sweden)

    Vinay Mohan

    2011-01-01

    Full Text Available The primary purpose of this study was to determine the oral manifestations of patients undergoing dialysis. Two subgroups of the population were studied: (1 Those who have been on dialysis for less than one year, (2 those who have been on dialysis for more than one year. Two dental indices–periodontal index and decayed, missing, filled index were used to identify periodontal status, dental canes activity. Data were compiled and analyzed by using the unpaired t-test. Results suggested that 100% (n = 26 of the patients undergoing dialysis presented with some form of periodontal disease (mean value = 2.24, standard deviation = 1.33. Majority of the patients displayed either established periodontal disease (57.6% or the beginning of periodontal disease (38 4%. Approximately, 70% of the patients had high decayed, missing, filled index (mean value = 6.19, standard deviation = 6.40. Findings led to the conclusion that patients on dialysis need comprehensive professional oral care and self-care instructions. The source of infection in oral cavity can cause variety of systemic diseases, causing morbidity and mortality in these immune-suppressed patients.

  6. rf reference line for PEP

    International Nuclear Information System (INIS)

    Schwarz, H.D.; Weaver, J.N.

    1979-03-01

    A rf phase reference line in 6 segments around the 2200 meter circumference PEP storage ring is described. Each segment of the reference line is phase stabilized by its own independent feedback system, which uses an amplitude modulated reflection from the end of each line. The modulation is kept small and decoupled from the next segment to avoid crosstalk and significant modulation of the rf drive signal. An error evaluation of the system is made. The technical implementation and prototype performance are described. Prototype tests indicate that the phase error around the ring can be held below 1 degree with this relatively simple system

  7. rf reference line for PEP

    Energy Technology Data Exchange (ETDEWEB)

    Schwarz, H.D.; Weaver, J.N.

    1979-03-01

    A rf phase reference line in 6 segments around the 2200 meter circumference PEP storage ring is described. Each segment of the reference line is phase stabilized by its own independent feedback system, which uses an amplitude modulated reflection from the end of each line. The modulation is kept small and decoupled from the next segment to avoid crosstalk and significant modulation of the rf drive signal. An error evaluation of the system is made. The technical implementation and prototype performance are described. Prototype tests indicate that the phase error around the ring can be held below 1 degree with this relatively simple system.

  8. Mobility-based Time References for Wireless Sensor Networks

    CERN Document Server

    Sebastiano, Fabio; Makinwa, Kofi A A

    2013-01-01

     This book describes the use of low-power low-cost and extremely small radios to provide essential time reference for wireless sensor networks.  The authors explain how to integrate such radios in a standard CMOS process to reduce both cost and size, while focusing on the challenge of designing a fully integrated time reference for such radios. To enable the integration of the time reference, system techniques are proposed and analyzed, several kinds of integrated time references are reviewed, and mobility-based references are identified as viable candidates to provide the required accuracy at low-power consumption. Practical implementations of a mobility-based oscillator and a temperature sensor are also presented, which demonstrate the required accuracy over a wide temperature range, while drawing 51-uW from a 1.2-V supply in a 65-nm CMOS process. Provides system analysis to understand requirements for time/frequency accuracy in wireless sensor networks; Describes system optimization for time references i...

  9. Reference frame for Product Configuration

    DEFF Research Database (Denmark)

    Ladeby, Klaes Rohde; Oddsson, Gudmundur Valur

    2011-01-01

    a reference frame for configuration that permits 1) a more precise understanding of a configuration system, 2) a understanding of how the configuration system relate to other systems, and 3) a definition of the basic concepts in configuration. The total configuration system, together with the definition...

  10. Examining egocentric and allocentric frames of reference in virtual space systems

    NARCIS (Netherlands)

    Friedman, A.

    2005-01-01

    The aim of this paper is to examine the egocentric and allocentric frames of reference, through evidence from both gesture and linguistic communication. The action of frames of reference, helps the user refer to the agent as a base for movement or to the object as a guiding point. We will show that

  11. Clinical Application of Different Surgical Navigation Systems in Complex Craniomaxillofacial Surgery: The Use of Multisurface 3-Dimensional Images and a 2-Plane Reference System.

    Science.gov (United States)

    Liu, Tom J; Ko, An-Ta; Tang, Yueh-Bih; Lai, Hong-Shiee; Chien, Hsiung-Fei; Hsieh, Thomas Mon-Hsian

    2016-04-01

    Intraoperative navigation is a tool that provides surgeons with real-time guidance based on patients' preoperative imaging studies. The application of intraoperative navigation to neurosurgery and otolaryngology has been well documented; however, only isolated reports have analyzed its potential in the field of craniomaxillofacial surgery. From November 2010 to July 2014, 15 patients were operated on for complex craniomaxillofacial surgery with assistance by 3 different navigation systems, which used either infrared or electromagnetic technologies. We imported fine-cut (0.625-mm) computed tomographic scan images of the patients to the navigation systems whose software processed them into multisurface 3-dimentional models used as guiding material for the surgical navigation. We also developed a simple "2-plane reference system" to ensure that the final results were symmetric to the normal half of the face. Appearance outcome was evaluated by questionnaire. Of these 15 cases, 3 cases were performed with infrared-based navigation, and the remaining 12 cases were accomplished by electromagnetic technology. Most of these cases resulted in satisfactory outcomes after tumor resection, posttraumatic reconstruction, and postablative reconstruction. Navigation systems offer highly valuable intraoperative assistance in complex craniomaxillofacial surgery. Not only can these systems pinpoint deep-seated lesions as neurosurgeons or otolaryngologists do, but they can also use a simple 2-plane reference system for accurate bone alignment. Moreover, advancements in multisurface 3-D models provide us more reliable intuitive image guidance. The application of electromagnetic technology, with its smaller reference obviation of the line-of-sight problem, makes the manipulation of craniomaxillofacial surgery more comfortable.

  12. A Nonlinear Attitude Estimator for Attitude and Heading Reference Systems Based on MEMS Sensors

    DEFF Research Database (Denmark)

    Wang, Yunlong; Soltani, Mohsen; Hussain, Dil muhammed Akbar

    2016-01-01

    In this paper, a nonlinear attitude estimator is designed for an Attitude Heading and Reference System (AHRS) based on Micro Electro-Mechanical Systems (MEMS) sensors. The design process of the attitude estimator is stated with detail, and the equilibrium point of the estimator error model...... the problems in previous research works. Moreover, the estimation of MEMS gyroscope bias is also inclueded in this estimator. The designed nonlinear attitude estimator is firstly tested in simulation environment and then implemented in an AHRS hardware for further experiments. Finally, the attitude estimation...

  13. Endogenous versus exogenous generic reference pricing for pharmaceuticals.

    Science.gov (United States)

    Antoñanzas, F; Juárez-Castelló, C A; Rodríguez-Ibeas, R

    2017-12-01

    In this paper we carry out a vertical differentiation duopoly model applied to pharmaceutical markets to analyze how endogenous and exogenous generic reference pricing influence competition between generic and branded drugs producers. Unlike the literature, we characterize for the exogenous case the equilibrium prices for all feasible relevant reference prices. Competition is enhanced after the introduction of a reference pricing system. We also compare both reference pricing systems on welfare grounds, assuming two different objective functions for health authorities: (i) standard social welfare and (ii) gross consumer surplus net of total pharmaceutical expenditures. We show that regardless of the objective function, health authorities will never choose endogenous reference pricing. When health authorities are paternalistic, the exogenous reference price that maximizes standard social welfare is such that the price of the generic drug is the reference price while the price of the branded drug is higher than the reference price. When health authorities are not paternalistic, the optimal exogenous reference price is such that the price of the branded drug is the reference price while the price of the generic drug is lower than the reference price.

  14. Characterisation of pristine Polish river systems and their use as reference conditions for Dutch river systems

    NARCIS (Netherlands)

    Nijboer, R.C.; Verdonschot, P.F.M.; Piechocki, A.; Tonczyk, G.; Klukowska, M.

    2006-01-01

    A central feature of the European Water Framework Directive are the reference conditions. The ecological quality status is determined by calculating the distance between the present situation and the reference conditions. To describe reference conditions the natural variation of biota in pristine

  15. Quantum reference frames and their applications to thermodynamics.

    Science.gov (United States)

    Popescu, Sandu; Sainz, Ana Belén; Short, Anthony J; Winter, Andreas

    2018-07-13

    We construct a quantum reference frame, which can be used to approximately implement arbitrary unitary transformations on a system in the presence of any number of extensive conserved quantities, by absorbing any back action provided by the conservation laws. Thus, the reference frame at the same time acts as a battery for the conserved quantities. Our construction features a physically intuitive, clear and implementation-friendly realization. Indeed, the reference system is composed of the same types of subsystems as the original system and is finite for any desired accuracy. In addition, the interaction with the reference frame can be broken down into two-body terms coupling the system to one of the reference frame subsystems at a time. We apply this construction to quantum thermodynamic set-ups with multiple, possibly non-commuting conserved quantities, which allows for the definition of explicit batteries in such cases.This article is part of a discussion meeting issue 'Foundations of quantum mechanics and their impact on contemporary society'. © 2018 The Author(s).

  16. Factors associated with mortality in a population with acute kidney injury undergoing hemodialysis in Peru

    Directory of Open Access Journals (Sweden)

    Percy Herrera-Añazco

    Full Text Available Abstract Introduction: Patients with acute kidney injury (AKI in developing countries are described in a profile of young age, with less comorbidities, with unifactorial, and with a lower mortality compared to patients in developed countries. Objective: To assess mortality in patients with acute kidney injury undergoing hemodialysis (HD and its associated factors in a developing country setting. Methods: Retrospective study. Demographic, clinical, and mortality variables were collected from patients who presented AKI and underwent HD between January 2014 and December 2015 at a national reference hospital in Lima, Peru. Risk ratios (RR and 95% confidence intervals (95%CI were estimated through Poisson regressions. Results: Data from 72 patients with AKI that underwent HD were analyzed, 66.7% of them were 8.9 mg/dL. The adjusted analysis showed that having had a creatinine level of > 8.9 mg/dL, compared to a creatinine level of < 5.2 mg/dL at the time of initiating HD, was associated with 74% less probability of death. Conclusion: Four out of every ten AKI patients undergoing HD die. Higher levels of creatinine were associated with lower probability of mortality.

  17. Verification of SAP reference models

    NARCIS (Netherlands)

    Dongen, van B.F.; Jansen-Vullers, M.H.; Aalst, van der W.M.P.; Benatallah, B.; Casati, F.

    2005-01-01

    To configure a process-aware information system (e.g., a workflow system, an ERP system), a business model needs to be transformed into an executable process model. Due to similarities in these transformations for different companies, databases with reference models, such as ARIS for MySAP, have

  18. Remote reference processing in MT survey using GPS clock; MT ho ni okeru GPS wo mochiita jikoku doki system

    Energy Technology Data Exchange (ETDEWEB)

    Yamane, K; Inoue, J; Takasugi, S [Geothermal Energy Research and Development Co. Ltd., Tokyo (Japan); Kosuge, S [DRICO Co. Ltd., Tokyo (Japan)

    1996-05-01

    A report is given about the application of a synchronizing system using clock signals from GPS satellites to a remote reference method which is a technique to reject noise from the MT method. This system uses the C/A code out of the L1 band waves from NAVSTAR/GPS satellites. The new system was operated in MT method-using investigations conducted at China Peninsula, Aichi Prefecture, and Izu Peninsula, Shizuoka Prefecture, with the reference points placed several 100km away in Iwate Prefecture on both occasions. It was found as the result that it is basically possible to catch signals from the GPS at any place, that the signals are accurate enough to be applied to time synchronization for the MT method, and that the signals assure a far remote reference method with a separation of several 100km between the sites involved. The referencing process at high frequencies whose feasibility had been doubted proved a success when highly correlated signals were exchanged between two stations over a distance of several 100km. 5 refs., 9 figs.

  19. Outcomes in Diabetic Patients Undergoing Orbital Atherectomy System.

    Science.gov (United States)

    Lee, Michael S; Shlofmitz, Evan; Nguyen, Heajung; Shlofmitz, Richard A

    2016-10-01

    We evaluated the angiographic and clinical outcomes of orbital atherectomy to treat severely calcified coronary lesions in diabetic and non-diabetic patients. Diabetics have increased risk for death, myocardial infarction, and target vessel revascularization after percutaneous coronary intervention. Severely calcified coronary lesions are associated with increased cardiac events. Orbital atherectomy facilitates stent delivery and optimizes stent expansion by modifying severely calcified plaque. Outcomes in diabetic patients who undergo orbital atherectomy have not been reported. Our retrospective multicenter registry included 458 consecutive real-world patients with severely calcified coronary arteries who underwent orbital atherectomy. The primary safety endpoint was the rate of major adverse cardiac and cerebrovascular events at 30 days. Diabetics represented 42.1% (193/458) of the entire cohort. The primary endpoint was similar in diabetics and non-diabetics (1.0% vs. 3.0%%, P = 0.20), as were 30-day rates of death (0.5% vs. 1.9%, P = 0.41), myocardial infarction (0.5% vs. 1.5%, P = 0.40), target vessel revascularization (0% vs. 0%, P = 1), and stroke (0% vs. 0.4%, P > 0.9). Angiographic complications and stent thrombosis rate were low and did not differ between the 2 groups. Diabetics represented a sizeable portion of patients who underwent orbital atherectomy. Diabetics who had severely calcified coronary arteries and underwent orbital atherectomy had low event rates that were similar to non-diabetics. Orbital atherectomy appears to be a viable treatment strategy for diabetic patients. Randomized trials with longer-term follow-up are needed to determine the ideal treatment strategy for diabetics. © 2016, Wiley Periodicals, Inc.

  20. Radiation exposure distribution in patients undergoing CT brain scans

    International Nuclear Information System (INIS)

    Yang Zhanshan; Feng Dinghua; Chang Zichi; Li Shijun

    1989-12-01

    The distribution of surface exposures in patients undergoing single and multiple computerized tomographic brain scans with Hitachi CT-W500 was measured by LiF(Mg, Ti) thermoluminescent dosimetry. It was found that there was no significant difference in the sufrace exposures from different scanning slices. However, the exposure doses at different scanning angles around the head were different significantly. The reference point of the maximum surface exposure was at the temporal part of the head. the maximum surface exposure was at 1.65 x 10 -3 C·kg -1 while the average exposure was 1.55 x 10 -3 C·kg -1 . The ratio of the average dose resulting from nine scans to that from a single scan was 1.3, and the surface exposure contribution of scattered radiation was computed. At the same time the radiation doses to eyes, thyroid, chest and gonads of patiens at corresponding position were also measured and were compared with those from CT cranial scans in children and skull radiographic procedures respectively

  1. Robust model reference adaptive output feedback tracking for uncertain linear systems with actuator fault based on reinforced dead-zone modification.

    Science.gov (United States)

    Bagherpoor, H M; Salmasi, Farzad R

    2015-07-01

    In this paper, robust model reference adaptive tracking controllers are considered for Single-Input Single-Output (SISO) and Multi-Input Multi-Output (MIMO) linear systems containing modeling uncertainties, unknown additive disturbances and actuator fault. Two new lemmas are proposed for both SISO and MIMO, under which dead-zone modification rule is improved such that the tracking error for any reference signal tends to zero in such systems. In the conventional approach, adaption of the controller parameters is ceased inside the dead-zone region which results tracking error, while preserving the system stability. In the proposed scheme, control signal is reinforced with an additive term based on tracking error inside the dead-zone which results in full reference tracking. In addition, no Fault Detection and Diagnosis (FDD) unit is needed in the proposed approach. Closed loop system stability and zero tracking error are proved by considering a suitable Lyapunov functions candidate. It is shown that the proposed control approach can assure that all the signals of the close loop system are bounded in faulty conditions. Finally, validity and performance of the new schemes have been illustrated through numerical simulations of SISO and MIMO systems in the presence of actuator faults, modeling uncertainty and output disturbance. Copyright © 2015 ISA. Published by Elsevier Ltd. All rights reserved.

  2. Anesthesia Preoperative Clinic Referral for Elevated Hba1c Reduces Complication Rate in Diabetic Patients Undergoing Total Joint Arthroplasty.

    Science.gov (United States)

    Kallio, Peter J; Nolan, Jenea; Olsen, Amy C; Breakwell, Susan; Topp, Richard; Pagel, Paul S

    2015-06-01

    Diabetes mellitus (DM) is risk factor for complications after orthopedic surgery. We tested the hypothesis that anesthesia preoperative clinic (APC) referral for elevated glycosylated hemoglobin (HbA1c) reduces complication rate after total joint arthroplasty (TJA). Patients (n = 203) with and without DM were chosen from 1,237 patients undergoing TJA during 2006 - 12. Patients evaluated in the APC had surgery in 2006 - 8 regardless of HbA1c (uncontrolled). Those evaluated between in subsequent two-year intervals were referred to primary care for HbA1c ≥ 10% and ≥ 8%, respectively, to improve DM control before surgery. Complications and mortality were quantified postoperatively and at three, six, and twelve months. Length of stay (LOS) and patients requiring a prolonged LOS (> 5 days) were recorded. Patients (197 men, 6 women) underwent 71, 131, and 1 total hip, knee, and shoulder replacements, respectively. Patients undergoing TJA with uncontrolled HbA1c and those with HbA1c patients without DM. An increase in complication rate was observed in DM patients with uncontrolled HbA1c versus patients without DM (P patients with preoperative HbA1c that was uncontrolled or ≥ 10% required prolonged LOS versus those without DM (P diabetics undergoing TJA.

  3. Preface: The International Reference Ionosphere (IRI) at equatorial latitudes

    Science.gov (United States)

    Reinisch, Bodo; Bilitza, Dieter

    2017-07-01

    This issue of Advances in Space Research includes papers that report and discuss improvements of the International Reference Ionosphere (IRI). IRI is the international standard for the representation of the plasma in Earth's ionosphere and recognized as such by the Committee on Space Research (COSPAR), the International Union of Radio Science (URSI), the International Telecommunication Union (ITU), and the International Standardization Organization (ISO). As requested, particularly by COSPAR and URSI, IRI is an empirical model relying on most of the available and reliable ground and space observations of the ionosphere. As new data become available and as older data sources are fully exploited the IRI model undergoes improvement cycles to stay as close to the existing data record as possible. The latest episode of this process is documented in the papers included in this issue using data from the worldwide network of ionosondes, from a few of the incoherent scatter radars, from the Alouette and ISIS topside sounders, and from the Global Navigation Satellite Systems (GNSS). The focus of this issue is on the equatorial and low latitude region that is of special importance for ionospheric physics because it includes the largest densities and steep density gradients in the double hump latitudinal structure, the Equatorial Ionization Anomaly (EIA), which is characteristic for this region.

  4. Effect of long-lived containers on the postclosure performance of a reference disposal system

    International Nuclear Information System (INIS)

    Goodwin, B.W.; Hajas, W.C.; LeNeveu, D.M.

    1996-05-01

    The concept for disposal of Canada's nuclear fuel waste involves isolating the waste in corrosion-resistant containers emplaced in a scaled vault at a depth of 500 to 1000 m in plutonic rock of the Canadian Shield. The concept permits a choice of methods, materials, site locations, and designs. The technical feasibility of this concept and its impact on the environment and human health are summarized in an Environmental Impact Statement (AECL 1994a,b), supported by nine detailed reference documents (Davis et al. 1993; Davison et al. 1994a,b; Goodwin et al. 1994; Greber et al. 1994; Grondin et al. 1994; Johnson et al. 1994a,b; Simmons and Baumgartner 1994). In the assessment of the reference disposal system, we assumed the containers encapsulating the nuclear fuel waste were constructed from Grade-2 titanium. In this report, we investigate the effect of a different choice, and assume the use of long-lived containers constructed from materials such as high-purity copper or Grades-12 or -16 titanium alloys. These alternative materials would provide much longer periods of protection, based on the expectation that the only container failure mechanism, for times up to 10 5 a, involves initial fabrication defects. We explore the effects of long-lived containers for the same vault layout and orientation that were assumed for the reference disposal vault. We also explore effects for two less favourable situations, in which the vault is closer to a nearby fracture zone and in which the vault is extended to have emplacement rooms on both sides of the fracture zone. Our analyses use the probabilistic assessment computer code, SYVAC3-CC3, an acronym for SYstems Variability Analysis Code, generation 3. with a system model describing the Canadian Concept, generation 3, for the disposal of nuclear fuel waste. The input data for the code have been adjusted to approximate the expected protection characteristics of alternative container materials. (author). 31 refs., 1 tab., 16 figs

  5. A Reference Architecture for Space Information Management

    Science.gov (United States)

    Mattmann, Chris A.; Crichton, Daniel J.; Hughes, J. Steven; Ramirez, Paul M.; Berrios, Daniel C.

    2006-01-01

    We describe a reference architecture for space information management systems that elegantly overcomes the rigid design of common information systems in many domains. The reference architecture consists of a set of flexible, reusable, independent models and software components that function in unison, but remain separately managed entities. The main guiding principle of the reference architecture is to separate the various models of information (e.g., data, metadata, etc.) from implemented system code, allowing each to evolve independently. System modularity, systems interoperability, and dynamic evolution of information system components are the primary benefits of the design of the architecture. The architecture requires the use of information models that are substantially more advanced than those used by the vast majority of information systems. These models are more expressive and can be more easily modularized, distributed and maintained than simpler models e.g., configuration files and data dictionaries. Our current work focuses on formalizing the architecture within a CCSDS Green Book and evaluating the architecture within the context of the C3I initiative.

  6. Software reference for SaTool - a Tool for Structural Analysis of Automated Systems

    DEFF Research Database (Denmark)

    Lorentzen, Torsten; Blanke, Mogens

    2004-01-01

    This software reference details the functions of SaTool – a tool for structural analysis of technical systems. SaTool is intended used as part of an industrial systems design cycle. Structural analysis is a graph-based technique where principal relations between variables express the system’s...... of the graph. SaTool makes analysis of the structure graph to provide knowledge about fundamental properties of the system in normal and faulty conditions. Salient features of SaTool include rapid analysis of possibility to diagnose faults and ability to make autonomous recovery should faults occur........ The list of such variables and functional relations constitute the system’s structure graph. Normal operation means all functional relations are intact. Should faults occur, one or more functional relations cease to be valid. In a structure graph, this is seen as the disappearance of one or more nodes...

  7. Reference reactor module for NASA's lunar surface fission power system

    Energy Technology Data Exchange (ETDEWEB)

    Poston, David I [Los Alamos National Laboratory; Kapernick, Richard J [Los Alamos National Laboratory; Dixon, David D [Los Alamos National Laboratory; Werner, James [INL; Qualls, Louis [ORNL; Radel, Ross [SNL

    2009-01-01

    Surface fission power systems on the Moon and Mars may provide the first US application of fission reactor technology in space since 1965. The Affordable Fission Surface Power System (AFSPS) study was completed by NASA/DOE to determine the cost of a modest performance, low-technical risk surface power system. The AFSPS concept is now being further developed within the Fission Surface Power (FSP) Project, which is a near-term technology program to demonstrate system-level TRL-6 by 2013. This paper describes the reference FSP reactor module concept, which is designed to provide a net power of 40 kWe for 8 years on the lunar surface; note, the system has been designed with technologies that are fully compatible with a Martian surface application. The reactor concept uses stainless-steel based. UO{sub 2}-fueled, pumped-NaK fission reactor coupled to free-piston Stirling converters. The reactor shielding approach utilizes both in-situ and launched shielding to keep the dose to astronauts much lower than the natural background radiation on the lunar surface. The ultimate goal of this work is to provide a 'workhorse' power system that NASA can utilize in near-term and future Lunar and Martian mission architectures, with the eventual capability to evolve to very high power, low mass systems, for either surface, deep space, and/or orbital missions.

  8. [Introduction of computerized anesthesia-recording systems and construction of comprehensive medical information network for patients undergoing surgery in the University of Tokyo Hospital].

    Science.gov (United States)

    Kitamura, Takayuki; Hoshimoto, Hiroyuki; Yamada, Yoshitsugu

    2009-10-01

    The computerized anesthesia-recording systems are expensive and the introduction of the systems takes time and requires huge effort. Generally speaking, the efficacy of the computerized anesthesia-recording systems on the anesthetic managements is focused on the ability to automatically input data from the monitors to the anesthetic records, and tends to be underestimated. However, once the computerized anesthesia-recording systems are integrated into the medical information network, several features, which definitely contribute to improve the quality of the anesthetic management, can be developed; for example, to prevent misidentification of patients, to prevent mistakes related to blood transfusion, and to protect patients' personal information. Here we describe our experiences of the introduction of the computerized anesthesia-recording systems and the construction of the comprehensive medical information network for patients undergoing surgery in The University of Tokyo Hospital. We also discuss possible efficacy of the comprehensive medical information network for patients during surgery under anesthetic managements.

  9. Microgrid cyber security reference architecture.

    Energy Technology Data Exchange (ETDEWEB)

    Veitch, Cynthia K.; Henry, Jordan M.; Richardson, Bryan T.; Hart, Derek H.

    2013-07-01

    This document describes a microgrid cyber security reference architecture. First, we present a high-level concept of operations for a microgrid, including operational modes, necessary power actors, and the communication protocols typically employed. We then describe our motivation for designing a secure microgrid; in particular, we provide general network and industrial control system (ICS)-speci c vulnerabilities, a threat model, information assurance compliance concerns, and design criteria for a microgrid control system network. Our design approach addresses these concerns by segmenting the microgrid control system network into enclaves, grouping enclaves into functional domains, and describing actor communication using data exchange attributes. We describe cyber actors that can help mitigate potential vulnerabilities, in addition to performance bene ts and vulnerability mitigation that may be realized using this reference architecture. To illustrate our design approach, we present a notional a microgrid control system network implementation, including types of communica- tion occurring on that network, example data exchange attributes for actors in the network, an example of how the network can be segmented to create enclaves and functional domains, and how cyber actors can be used to enforce network segmentation and provide the neces- sary level of security. Finally, we describe areas of focus for the further development of the reference architecture.

  10. Positron emission tomography in patients with aggressive fibromatosis/desmoid tumours undergoing therapy with imatinib

    Energy Technology Data Exchange (ETDEWEB)

    Kasper, Bernd; Hohenberger, Peter [University of Heidelberg, Sarcoma Unit, ITM - Interdisciplinary Tumor Center Mannheim, Mannheim University Medical Center, Mannheim (Germany); Dimitrakopoulou-Strauss, Antonia; Strauss, Ludwig G. [German Cancer Research Center, Clinical Cooperation Unit Nuclear Medicine, Heidelberg (Germany)

    2010-10-15

    We used {sup 18}F-FDG PET to evaluate the FDG uptake in patients with aggressive fibromatosis (AF, also known as desmoid tumours) undergoing therapy with imatinib (imatinib mesylate, Glivec). The pilot study included nine patients with progressive AF receiving oral treatment with imatinib at a daily dose of 800 mg. Patients were examined using PET prior to the start of therapy and during imatinib treatment. Restaging according to the Response Evaluation Criteria in Solid Tumors (RECIST) was performed in parallel using CT and/or MRI and served as reference. The clinical outcomes in nine evaluable patients were as follows: seven patients with stable disease, and two patients with progressive disease. A 27% decrease in the median average standardized uptake value (SUV) of the sequential PET examinations was demonstrated in all evaluable patients with three patients (33%) showing a decrease in SUV of more than 40% (48%, 52% and 54%, respectively); no patient showed a substantial increase in SUV. To our knowledge, this is the first series of AF patients undergoing treatment with imatinib and monitored using sequential PET imaging, that allows detection of SUV changes after imatinib induction, thus helping to decide whether treatment should be continued or not. (orig.)

  11. Realization of a reference system for the generation radon 222

    International Nuclear Information System (INIS)

    Guelin, M.

    1990-11-01

    After some general considerations on radon and its calibration techniques, the methods and technologies developed in order to realize a reference system for the generation of radon 222 are presented. Two original patented techniques have been developed. The former technique deals with the realization of radon 222 solid sources from radium 226 deposit on acrylic fibres. This new technology offers the advantage of very quickly obtaining a constant emission rate near to 100%. The latter technique deals with the standard measurement of radon 222 volumic activity via gamma spectrometry of its short-lived daughters. This new procedure is the only one allowing to relate this measure to gaseous standards. An aeraulic/ventilation circuit makes it possible to calibrate the radon measurement instrumentation within a wide volumic activity range from to 4 to 4 000 Bq/m 3

  12. Dosimetric methodology and reference system for diagnostic level X radiation

    International Nuclear Information System (INIS)

    Potiens, Maria da Penha Albuquerque

    1999-01-01

    Several methodologies for the calibration of diagnostic radiology instruments were developed and established at the Calibration Laboratory of IPEN. These established radiation qualities are recommended by international standards. The methods may be used in the calibration procedures of survey meters used in radiation protection measurements (scattered radiation), instruments used in direct beams (attenuated and non attenuated beams) and quality control instruments. A reference system was proposed using two identical ionization chambers developed at IPEN. They differ only by the collecting electrode material, one of aluminium and the other of graphite. The different energetic dependence of the chamber's response provided a ratio related to the tube potential. The variation of only 0.28%, from 14.3 to 111 keV, on the energetic dependence of the graphite electrode chamber, provided the possibility of air kerma rate determination in the studied radiation beams. (author)

  13. Disposable Miniaturized Screen‐Printed pH and Reference Electrodes for Potentiometric Systems

    DEFF Research Database (Denmark)

    Musa, Arnaud Emmanuel; del Campo, Francisco Javier; Abramova, Natalia

    2011-01-01

    This work describes the development of a miniaturized potentiometric system comprising a miniaturized quasi‐reference electrode (QRE) coupled to a solid‐state ion‐selective electrode (ISE) for the monitoring of pH. We describe the optimization of materials and fabrication processes including screen‐printing...... electrode) that can be used continuously for a period of not less than 7 days in aqueous solutions. Curing the Ag/AgCl pastes during 20 minutes at 120 °C after printing allowed the QREs to display excellent potential stability, as demonstrated by an open‐circuit‐potential standard deviation of ±1.2 mV over...

  14. Method of collective variables with reference system for the grand canonical ensemble

    International Nuclear Information System (INIS)

    Yukhnovskii, I.R.

    1989-01-01

    A method of collective variables with special reference system for the grand canonical ensemble is presented. An explicit form is obtained for the basis sixth-degree measure density needed to describe the liquid-gas phase transition. Here the author presents the fundamentals of the method, which are as follows: (1) the functional form for the partition function in the grand canonical ensemble; (2) derivation of thermodynamic relations for the coefficients of the Jacobian; (3) transition to the problem on an adequate lattice; and (4) obtaining of the explicit form for the functional of the partition function

  15. The role of cystovaginoscopy and hygienic advice in girls referred for symptoms of vulvovaginitis.

    Science.gov (United States)

    Ram, Ashok Daya; Hurst, Katherine Victoria; Steinbrecher, Henrik

    2012-05-01

    Vulvovaginitis is a common presenting symptom referred to a paediatric urology clinic. Some of these patients undergo diagnostic cystovaginoscopy to determine whether there is any underlying anatomical cause for the persistent infection. However, in the majority of the patients, no underlying abnormality is found and they are given hygienic advice and prescribed bio yoghurt postoperatively. This study examines the outcome in these patients after hygienic advice is given: determining whether cystovaginoscopy was really necessary and whether it changed the management of vulvovaginitis.

  16. Systems analysis programs for hands-on integrated reliability evaluations (SAPHIRE) version 5.0, technical reference manual

    International Nuclear Information System (INIS)

    Russell, K.D.; Atwood, C.L.; Galyean, W.J.; Sattison, M.B.; Rasmuson, D.M.

    1994-07-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) refers to a set of several microcomputer programs that were developed to create and analyze probabilistic risk assessments (PRAs), primarily for nuclear power plants. This volume provides information on the principles used in the construction and operation of Version 5.0 of the Integrated Reliability and Risk Analysis System (IRRAS) and the System Analysis and Risk Assessment (SARA) system. It summarizes the fundamental mathematical concepts of sets and logic, fault trees, and probability. This volume then describes the algorithms that these programs use to construct a fault tree and to obtain the minimal cut sets. It gives the formulas used to obtain the probability of the top event from the minimal cut sets, and the formulas for probabilities that are appropriate under various assumptions concerning repairability and mission time. It defines the measures of basic event importance that these programs can calculate. This volume gives an overview of uncertainty analysis using simple Monte Carlo sampling or Latin Hypercube sampling, and states the algorithms used by these programs to generate random basic event probabilities from various distributions. Further references are given, and a detailed example of the reduction and quantification of a simple fault tree is provided in an appendix

  17. Two-fluid equations for a nuclear system with arbitrary motions

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Byoung Jae [Chungnam National University, Daejeon (Korea, Republic of); Kim, Kyung Doo [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    Ocean nuclear systems include a seabed-type plant, a floating-type plant, and a nuclear-propulsion ship. We asked ourselves, 'What governing equations should be used for ocean nuclear systems?' Since ocean nuclear systems are apt to move arbitrarily, the two-fluid model must be formulated in the non-inertial frame of reference that is undergoing acceleration with respect to an inertial frame. Two-phase flow systems with arbitrary motions are barely reported. Kim et al. (1996) added the centripetal and Euler acceleration forces to the homogeneous equilibrium momentum equation embedded in the RETRAN code. However, they did not look into the mass and energy equations. The purpose of this study is to derive general two-fluid equations in the non-inertial frame of reference, which can be used for safety analysis of ocean nuclear systems. The two-fluid equation forms for scalar properties such as mass, internal energy, and enthalpy equation in the moving frame are the same as those in the absolute frame. On the other hand, the fictitious effect must be included in the momentum equation.

  18. CCF analysis of high redundancy systems safety/relief valve data analysis and reference BWR application

    International Nuclear Information System (INIS)

    Mankamo, T.; Bjoere, S.; Olsson, Lena

    1992-12-01

    Dependent failure analysis and modeling were developed for high redundancy systems. The study included a comprehensive data analysis of safety and relief valves at the Finnish and Swedish BWR plants, resulting in improved understanding of Common Cause Failure mechanisms in these components. The reference application on the Forsmark 1/2 reactor relief system, constituting of twelve safety/relief lines and two regulating relief lines, covered different safety criteria cases of reactor depressurization and overpressure protection function, and failure to re close sequences. For the quantification of dependencies, the Alpha Factor Model, the Binomial Probability Model and the Common Load Model were compared for applicability in high redundancy systems

  19. Reference handbook: Level detectors

    International Nuclear Information System (INIS)

    1990-01-01

    The purpose of this handbook is to provide Rocky Flats personnel with the information necessary to understand level measurement and detection. Upon completion of this handbook you should be able to do the following: List three reasons for measuring level. Describe the basic operating principles of the sight glass. Demonstrate proper techniques for reading a sight glass. Describe the basic operating principles of a float level detector. Describe the basic operating principles of a bubbler level indicating system. Explain the differences between a wet and dry reference leg indicating system, and describe how each functions. This handbook is designed for use by experienced Rocky Flats operators to reinforce and improve their current knowledge level, and by entry-level operators to ensure that they possess a minimum level of fundamental knowledge. Level Detectors is applicable to many job classifications and can be used as a reference for classroom work or for self-study. Although this reference handbook is by no means all-encompassing, you will gain enough information about this subject area to assist you in contributing to the safe operation of Rocky Flats Plant

  20. New reference trajectory optimization algorithm for a flight management system inspired in beam search

    Directory of Open Access Journals (Sweden)

    Alejandro MURRIETA-MENDOZA

    2017-08-01

    Full Text Available With the objective of reducing the flight cost and the amount of polluting emissions released in the atmosphere, a new optimization algorithm considering the climb, cruise and descent phases is presented for the reference vertical flight trajectory. The selection of the reference vertical navigation speeds and altitudes was solved as a discrete combinatory problem by means of a graph-tree passing through nodes using the beam search optimization technique. To achieve a compromise between the execution time and the algorithm’s ability to find the global optimal solution, a heuristic methodology introducing a parameter called “optimism coefficient was used in order to estimate the trajectory’s flight cost at every node. The optimal trajectory cost obtained with the developed algorithm was compared with the cost of the optimal trajectory provided by a commercial flight management system(FMS. The global optimal solution was validated against an exhaustive search algorithm(ESA, other than the proposed algorithm. The developed algorithm takes into account weather effects, step climbs during cruise and air traffic management constraints such as constant altitude segments, constant cruise Mach, and a pre-defined reference lateral navigation route. The aircraft fuel burn was computed using a numerical performance model which was created and validated using flight test experimental data.

  1. Design and realization of the high-precision weighing systems as the gravimetric references in PTB's national water flow standard

    International Nuclear Information System (INIS)

    Engel, Rainer; Beyer, Karlheinz; Baade, Hans-Joachim

    2012-01-01

    PTB's ‘Hydrodynamic Test Field’, which represents a high-accuracy water flow calibration facility, serves as the national primary standard for liquid flow measurands. As the core reference device of this flow facility, a gravimetric standard has been incorporated, which comprises three special-design weighing systems: 300 kg, 3 tons and 30 tons. These gravimetric references were realized as a combination of a strain-gauge-based and an electromagnetic-force-compensation load-cell-based balance, each. Special emphasis had to be placed upon the dynamics design of the whole weighing system, due to the high measurement resolution and the dynamic behavior of the weighing systems, which are dynamically affected by mechanical vibrations caused by environmental impacts, flow machinery operation, flow noise in the pipework and induced wave motions in the weigh tanks. Taking into account all the above boundary conditions, the design work for the gravimetric reference resulted in a concrete foundation ‘rock’ of some 300 tons that rests on a number of vibration isolators. In addition to these passively operating vibration isolators, the vibration damping effect is enhanced by applying an electronic level regulation device. (paper)

  2. Zotero : a free and open-source reference manager

    DEFF Research Database (Denmark)

    Courraud, Julie

    2014-01-01

    Zotero is a free, open-source reference management program compatible with Linux®, Mac®, and Windows® operating systems. Libraries are backed up online allowing sharing between computers and even multiple users. Zotero makes it easy to keep your reference library organised and ‘clean’. Reference...

  3. Comparison of pain scores between patients undergoing panretinal photocoagulation using navigated or pattern scan laser systems

    Directory of Open Access Journals (Sweden)

    Umit Ubeyt Inan

    2016-02-01

    Full Text Available ABSTRACT Purpose: To compare the pain responses of patients with proliferative diabetic retinopathy (PDR undergoing panretinal photocoagulation (PRP using either pattern scan laser (PASCAL or navigated laser photocoagulation (NAVILAS. Methods: Patients diagnosed with PDR were randomly assigned to undergo either PASCAL or NAVILAS photocoagulation treatment. PRP was performed using the multi-shot mode with a spot size of 200-400 µm and a pulse duration of 30 ms to obtain a white-grayish spot on the retina. Parameters were identical in both procedures. After 30 min of PRP application, patients were asked to verbally describe their pain perception as either "none," "mild," "moderate," "severe," or "very severe" using a verbal rating scale (VRS and visual analog scale (VAS by indicating a score from "0" to "10," representing the severity of pain from "no pain" to "severe pain." Results: A total of 60 eyes of 60 patients (20 females and 40 males diagnosed with PDR were treated. The mean age of patients was 62.22 ± 9.19 years, and the mean diabetes duration was 195.47 ± 94.54 months. The mean number of laser spots delivered during PRP was 389.47 ± 71.52 in the NAVILAS group and 392.70 ± 54.33 in the PASCAL group (p=0.57. The difference in pain responses between patients in the NAVILAS and PASCAL groups was significant with regard to the mean VRS (1.10 ± 0.67 and 1.47 ± 0.69, respectively; p=0.042 and mean VAS (2.13 ± 1.17 and 2.97 ± 1.35, respectively; p=0.034 scores. Conclusions: Pain responses in patients undergoing PRP with a 30-ms pulse duration were significantly milder in the NAVILAS group than in the PASCAL group.

  4. Assessment of the periodontal health status in patients undergoing orthodontic treatment with fixed appliances and Invisalign system

    Science.gov (United States)

    Lu, Haili; Tang, Haifang; Zhou, Tian; Kang, Na

    2018-01-01

    Abstract Background: At present, many scholars have studied the periodontal health status of patients undergoing orthodontic treatment with fixed appliances and invisalign. However, those results are inconsistent. Therefore, we conducted this meta-analysis, and then provide reference for clinical treatment. Methods: Most databases, such as the Cochrane Library, EMBASE, PubMed, Medline, Chinese Biomedical Literature Database, CNKI, and Wan Fang Data were retrieved for related articles from the establishment of the database to October 2017. Meanwhile, we also searched the references of the related literatures manually, in order to increase the included literatures. Two researchers screened the related literatures according to the inclusion criteria and exclusion criteria. Stata 12.0 software was used for data analysis, and results are estimated by odds ratio (OR) and 95% confidence interval (CI). Results: Finally, 7 articles, including 368 patients, were included into our meta-analysis. Meta-analysis results showed that there was no statistically significant difference of gingival index (GI) and sulcus probing depth (SPD) status between the invisalign group and the control group, including at 1, 3, and 6 months (all P > .05). When compared with the control group, the invisalign group presented a lower plaque index (PLI) and sulcus bleeding index (SBI) status at 1 month (OR = −0.53, 95% CI: −0.89 to −0.18; OR = −0.44, 95% CI: −0.70 to −0.19, respectively), 3 months (OR = −0.69, 95% CI: −1.12 to −0.27; OR = −0.49, 95% CI: −0.93 to −0.05, respectively), and 6 months (OR = −0.91, 95% CI: −1.47 to −0.35; OR = −0.40, 95% CI: −0.63 to −0.07, respectively). Subgroup analysis showed that the SPD status was lower in the invisalign group at 6 months when measured the teeth using Ramfjord index (OR = −0.74, 95% CI: −1.35 to −0.12). However, there was no statistically significant difference between the 2

  5. Development of Reference Source Terms for EU-APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Kim, ByungIl; Lee, Chonghui; Lee, Dongsu; Ko, Heejin; Kang, Sangho [KEPCO Engineering and Construction Co. Inc., Yongin (Korea, Republic of)

    2014-05-15

    These source terms are developed for the typical U. S. NPP and do not reflect the design characteristics of EU-APR1400 (1,400 MWe PWR) which will be applied for the EUR certification in European countries. The process of developing the RST for EU-APR1400 is to undergo a similar process that NUREG-1465 had gone through when it came out with its proposed source terms. The purpose of this study is to develop the EU-APR1400 design-specific RST complied with the EUR. The Large LOCA is the reference equence used in the NUREG-1465 evaluation, whereas the EUAPR1400 risk-significant sequences are dominated by small LOCA and non-LOCA sequences. Moreover, when considering the EU-APR1400 has many design features to mitigate the consequences of severe accident phenomena, it is not surprising that the aspects of both release fractions and durations are distinctly different from NUREG-1465. This RST will be continuously updated to reflect to the design features of EU-APR1400, and then, be used as the reference for design purposes such as criteria satisfaction of radioactivity releases, equipment survivability, control room habitability for severe accident, and so on.

  6. A Software Reference Architecture for Service-Oriented 3D Geovisualization Systems

    Directory of Open Access Journals (Sweden)

    Dieter Hildebrandt

    2014-12-01

    Full Text Available Modern 3D geovisualization systems (3DGeoVSs are complex and evolving systems that are required to be adaptable and leverage distributed resources, including massive geodata. This article focuses on 3DGeoVSs built based on the principles of service-oriented architectures, standards and image-based representations (SSI to address practically relevant challenges and potentials. Such systems facilitate resource sharing and agile and efficient system construction and change in an interoperable manner, while exploiting images as efficient, decoupled and interoperable representations. The software architecture of a 3DGeoVS and its underlying visualization model have strong effects on the system’s quality attributes and support various system life cycle activities. This article contributes a software reference architecture (SRA for 3DGeoVSs based on SSI that can be used to design, describe and analyze concrete software architectures with the intended primary benefit of an increase in effectiveness and efficiency in such activities. The SRA integrates existing, proven technology and novel contributions in a unique manner. As the foundation for the SRA, we propose the generalized visualization pipeline model that generalizes and overcomes expressiveness limitations of the prevalent visualization pipeline model. To facilitate exploiting image-based representations (IReps, the SRA integrates approaches for the representation, provisioning and styling of and interaction with IReps. Five applications of the SRA provide proofs of concept for the general applicability and utility of the SRA. A qualitative evaluation indicates the overall suitability of the SRA, its applications and the general approach of building 3DGeoVSs based on SSI.

  7. A new method of 3-D cephalometry Part I: the anatomic Cartesian 3-D reference system.

    NARCIS (Netherlands)

    Swennen, G.R.J.; Schutyser, F.A.C.; Barth, E.L.; Groeve, P. De; Mey, A. De

    2006-01-01

    The purpose of this study was to present a new innovative three-dimensional (3-D) cephalometric method. Part I deals with the set-up and validation of a voxel-based semi-automatic 3-D cephalometric reference system. The CT data (DICOM 3.0 files) of 20 control patients with normal skeletal

  8. Improved level of function in an individual with Carcinoma of the pyriform sinus undergoing radiotherapy: A case report study

    Directory of Open Access Journals (Sweden)

    A K Akhil

    2017-01-01

    Full Text Available A 72-year-old female with a history of cough and difficulty in swallowing was admitted in KLE Cancer Hospital and was diagnosed with carcinoma of the pyriform sinus, where she was undergoing radiotherapy and was referred for physiotherapy. On examination, she had chest secretion, cough, breathlessness, and generalized body weakness that led to functional limitations. Pre- and postfunctional assessment was done with the help of Functional independence measure (FIMS scale. A 10-day physiotherapy intervention was given and post intervention evaluation showed an increased functional level.

  9. The Use of Reference Models in Business Process Renovation

    Directory of Open Access Journals (Sweden)

    Dejan Pajk

    2010-01-01

    Full Text Available Enterprise resource planning (ERP systems are often used by companies to automate and enhance their busi- ness processes. The capabilities of ERP systems can be described by best-practice reference models. The purpose of the article is to demonstrate the business process renovation approach with the use of reference models. Although the use of reference models brings many positive effects for business, they are still rarely used in Slovenian small and medium-sized compa- nies. The reasons for this may be found in the reference models themselves as well as in project implementation methodologies. In the article a reference model based on Microsoft Dynamics NAV is suggested. The reference model is designed using upgraded BPMN notation with additional business objects, which help to describe the models in more detail.

  10. A new birthweight reference in Guangzhou, southern China, and its comparison with the global reference.

    Science.gov (United States)

    He, Jian-Rong; Xia, Hui-Min; Liu, Yu; Xia, Xiao-Yan; Mo, Wei-Jian; Wang, Ping; Cheng, Kar Keung; Leung, Gabriel M; Feng, Qiong; Schooling, C Mary; Qiu, Xiu

    2014-12-01

    To formulate a new birthweight reference for different gestational ages in Guangzhou, southern China, and compare it with the currently used reference in China and the global reference. All singleton live births of more than 26 weeks' gestational age recorded in the Guangzhou Perinatal Health Care and Delivery Surveillance System for the years 2009, 2010 and 2011 (n=510 837) were retrospectively included in the study. In addition, the study sample was supplemented by all singleton live births (n=3538) at gestational ages 26-33 weeks from 2007 and 2008. We used Gaussian mixture models and robust regression to exclude outliers of birth weight and then applied Generalized Additive Models for Location, Scale, and Shape (GAMLSS) to generate smoothed percentile curves separately for gender and parity. Of infants defined as small for gestational age (SGA) in the new reference, 15.3-47.7% (depending on gestational age) were considered appropriate for gestational age (AGA) by the currently used reference of China. Of the infants defined as SGA by the new reference, 9.2% with gestational ages 34-36 weeks and 14.3% with 37-41 weeks were considered AGA by the global reference. At the 50th centile line, the new reference curve was similar to that of the global reference for gestational ages 26-33 weeks and above the global reference for 34-40 weeks. The new birthweight reference based on birthweight data for neonates in Guangzhou, China, differs from the reference currently used in China and the global reference, and appears to be more relevant to the local population. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  11. Python pocket reference, version 2.4

    CERN Document Server

    Lutz, Mark

    2005-01-01

    Python is optimized for quality, productivity, portability, and integration. Hundreds of thousands of Python developers around the world rely on Python for general-purpose tasks, Internet scripting, systems programming, user interfaces, and product customization. Available on all major computing platforms, including commercial versions of Unix, Linux, Windows, and Mac OS X, Python is portable, powerful and remarkable easy to use. With its convenient, quick-reference format, Python Pocket Reference, 3rd Edition is the perfect on-the-job reference. More importantly, it's now been refreshed

  12. Spatial nonlinearities: Cascading effects in the earth system

    Science.gov (United States)

    Peters, Debra P.C.; Pielke, R.A.; Bestelmeyer, B.T.; Allen, Craig D.; Munson-McGee, Stuart; Havstad, K. M.; Canadell, Josep G.; Pataki, Diane E.; Pitelka, Louis F.

    2006-01-01

    Nonlinear behavior is prevalent in all aspects of the Earth System, including ecological responses to global change (Gallagher and Appenzeller 1999; Steffen et al. 2004). Nonlinear behavior refers to a large, discontinuous change in response to a small change in a driving variable (Rial et al. 2004). In contrast to linear systems where responses are smooth, well-behaved, continuous functions, nonlinear systems often undergo sharp or discontinuous transitions resulting from the crossing of thresholds. These nonlinear responses can result in surprising behavior that makes forecasting difficult (Kaplan and Glass 1995). Given that many system dynamics are nonlinear, it is imperative that conceptual and quantitative tools be developed to increase our understanding of the processes leading to nonlinear behavior in order to determine if forecasting can be improved under future environmental changes (Clark et al. 2001).

  13. Development of Power Controller System based on Model Reference Adaptive Control for a Nuclear Reactor

    International Nuclear Information System (INIS)

    Mohd Sabri Minhat; Izhar Abu Hussin; Ridzuan Abdul Mutalib

    2014-01-01

    The Reactor TRIGA PUSPATI (RTP)-type TRIGA Mark II was installed in the year 1982. The Power Controller System (PCS) or Automated Power Controller System (APCS) is very important for reactor operation and safety reasons. It is a function of controlled reactivity and reactor power. The existing power controller system is under development and due to slow response, low accuracy and low stability on reactor power control affecting the reactor safety. The nuclear reactor is a nonlinear system in nature, and it is power increases continuously with time. The reactor parameters vary as a function of power, fuel burnup and control rod worth. The output power value given by the power control system is not exactly as real value of reactor power. Therefore, controller system design is very important, an adaptive controller seems to be inevitable. The method chooses is a linear controller by using feedback linearization, for example Model Reference Adaptive Control. The developed APCS for RTP will be design by using Model Reference Adaptive Control (MRAC). The structured of RTP model to produce the dynamic behaviour of RTP on entire operating power range from 0 to 1MWatt. The dynamic behavior of RTP model is produced by coupling of neutronic and thermal-hydraulics. It will be developed by using software MATLAB/Simulink and hardware module card to handle analog input signal. A new algorithm for APCS is developed to control the movement of control rods with uniformity and orderly for RTP. Before APCS test to real plant, simulation results shall be obtained from RTP model on reactor power, reactivity, period, control rod positions, fuel and coolant temperatures. Those data are comparable with the real data for validation. After completing the RTP model, APCS will be tested to real plant on power control system performance by using real signal from RTP including fail-safe operation, system reliable, fast response, stability and accuracy. The new algorithm shall be a satisfied

  14. On Learning to Write Those **** References

    Science.gov (United States)

    Hartley, James

    2014-01-01

    In this article, the author discusses how difficult it is for psychology college students to learn to write multiple disciplines of references. It is hard for students to understand why all details have to be written in the right order and the right type-style--depending upon which reference system is used. In this article, the author proposes…

  15. Genetics Home Reference: systemic scleroderma

    Science.gov (United States)

    ... Facebook Twitter Home Health Conditions Systemic scleroderma Systemic scleroderma Printable PDF Open All Close All Enable Javascript to view the expand/collapse boxes. Description Systemic scleroderma is an autoimmune disorder that affects the skin ...

  16. Distributed Consensus Tracking for Second-Order Nonlinear Multiagent Systems with a Specified Reference State

    Directory of Open Access Journals (Sweden)

    Guoguang Wen

    2014-01-01

    Full Text Available This paper mainly addresses the distributed consensus tracking problem for second-order nonlinear multiagent systems with a specified reference trajectory. The dynamics of each follower consists of two terms: nonlinear inherent dynamics and a simple communication protocol relying only on the position and velocity information of its neighbors. The consensus reference is taken as a virtual leader, whose output is only its position and velocity information that is available to only a subset of a group of followers. To achieve consensus tracking, a class of nonsmooth control protocols is proposed which reply on the relative information among the neighboring agents. Then some corresponding sufficient conditions are derived. It is shown that if the communication graph associated with the virtual leader and followers is connected at each time instant, the consensus can be achieved at least globally exponentially with the proposed protocol. Rigorous proofs are given by using graph theory, matrix theory, and Lyapunov theory. Finally, numerical examples are presented to illustrate the theoretical analysis.

  17. Evaluation of reference genes for gene expression analysis using quantitative RT-PCR in Azospirillum brasilense.

    Science.gov (United States)

    McMillan, Mary; Pereg, Lily

    2014-01-01

    Azospirillum brasilense is a nitrogen fixing bacterium that has been shown to have various beneficial effects on plant growth and yield. Under normal conditions A. brasilense exists in a motile flagellated form, which, under starvation or stress conditions, can undergo differentiation into an encapsulated, cyst-like form. Quantitative RT-PCR can be used to analyse changes in gene expression during this differentiation process. The accuracy of quantification of mRNA levels by qRT-PCR relies on the normalisation of data against stably expressed reference genes. No suitable set of reference genes has yet been described for A. brasilense. Here we evaluated the expression of ten candidate reference genes (16S rRNA, gapB, glyA, gyrA, proC, pykA, recA, recF, rpoD, and tpiA) in wild-type and mutant A. brasilense strains under different culture conditions, including conditions that induce differentiation. Analysis with the software programs BestKeeper, NormFinder and GeNorm indicated that gyrA, glyA and recA are the most stably expressed reference genes in A. brasilense. The results also suggested that the use of two reference genes (gyrA and glyA) is sufficient for effective normalisation of qRT-PCR data.

  18. Evaluation of reference genes for gene expression analysis using quantitative RT-PCR in Azospirillum brasilense.

    Directory of Open Access Journals (Sweden)

    Mary McMillan

    Full Text Available Azospirillum brasilense is a nitrogen fixing bacterium that has been shown to have various beneficial effects on plant growth and yield. Under normal conditions A. brasilense exists in a motile flagellated form, which, under starvation or stress conditions, can undergo differentiation into an encapsulated, cyst-like form. Quantitative RT-PCR can be used to analyse changes in gene expression during this differentiation process. The accuracy of quantification of mRNA levels by qRT-PCR relies on the normalisation of data against stably expressed reference genes. No suitable set of reference genes has yet been described for A. brasilense. Here we evaluated the expression of ten candidate reference genes (16S rRNA, gapB, glyA, gyrA, proC, pykA, recA, recF, rpoD, and tpiA in wild-type and mutant A. brasilense strains under different culture conditions, including conditions that induce differentiation. Analysis with the software programs BestKeeper, NormFinder and GeNorm indicated that gyrA, glyA and recA are the most stably expressed reference genes in A. brasilense. The results also suggested that the use of two reference genes (gyrA and glyA is sufficient for effective normalisation of qRT-PCR data.

  19. Integrated Reliability and Risk Analysis System (IRRAS), Version 2.5: Reference manual

    International Nuclear Information System (INIS)

    Russell, K.D.; McKay, M.K.; Sattison, M.B.; Skinner, N.L.; Wood, S.T.; Rasmuson, D.M.

    1991-03-01

    The Integrated Reliability and Risk Analysis System (IRRAS) is a state-of-the-art, microcomputer-based probabilistic risk assessment (PRA) model development and analysis tool to address key nuclear plant safety issues. IRRAS is an integrated software tool that gives the user the ability to create and analyze fault trees and accident sequences using a microcomputer. This program provides functions that range from graphical fault tree construction to cut set generation and quantification. Version 1.0 of the IRRAS program was released in February of 1987. Since that time, many user comments and enhancements have been incorporated into the program providing a much more powerful and user-friendly system. This version has been designated IRRAS 2.5 and is the subject of this Reference Manual. Version 2.5 of IRRAS provides the same capabilities as Version 1.0 and adds a relational data base facility for managing the data, improved functionality, and improved algorithm performance. 7 refs., 348 figs

  20. Reference costs of electricity

    International Nuclear Information System (INIS)

    Terraz, N.

    1997-01-01

    The calculation of electric power production reference costs is used in France, even in the present case of over-capacity, for comparing the relative interest of the various means of power generation (nuclear plants, coal plants, hydroelectricity, gas combined cycles, etc.) and as an aid for future investment decisions. Reference costs show a sharp decrease between 1993 and 1997 due to advancements in nuclear plant operating ability and fossil fuel price decrease. Actuarial rates, plant service life, fuel costs and exchange rates are important parameters. The various costs from the research stage to the waste processing stages are discussed and the reference costs of the various power generation systems are presented and compared together with their competitiveness; the future of wind energy and cogeneration and the prospective of the renewal of nuclear plants at the 2010 horizon are also addressed

  1. Electroacoustical reference data

    CERN Document Server

    Eargle, John M

    2002-01-01

    The need for a general collection of electroacoustical reference and design data in graphical form has been felt by acousticians and engineers for some time. This type of data can otherwise only be found in a collection of handbooks. Therefore, it is the author's intention that this book serve as a single source for many electroacoustical reference and system design requirements. In form, the volume closely resembles Frank Massa's Acoustic Design Charts, a handy book dating from 1942 that has long been out of print. The basic format of Massa's book has been followed here: For each entry, graphical data are presented on the right page, while text, examples, and refer­ ences appear on the left page. In this manner, the user can solve a given problem without thumbing from one page to the next. All graphs and charts have been scaled for ease in data entry and reading. The book is divided into the following sections: A. General Acoustical Relationships. This section covers the behavior of sound transmis­ sion in...

  2. Application of an electronic bulletin board, as a mechanism of coordination of actions in complex systems - reference model

    Directory of Open Access Journals (Sweden)

    Katarzyna Grzybowska

    2015-06-01

    Full Text Available Background: In her previous research, the author of this publication indicates that coordination is a dependent variable which has a great driving force and is a very unstable factor. This results in the fact that all of the actions connected with coordination have an impact on other factors of cooperation as well as the integration of the enterprises in the structures of a supply chain type structure. Material and methods:  The article has been divided into two basic parts. The first part regards the reference models in complex systems (supply chain systems. They can constitute a starting point for the modelling of target processes in the built supply chain structure. The second part presents template process models (Reference Models for selected action coordination mechanisms during enterprise cooperation. The aim of the article is the presentation the model an Electronic Bulletin Board (EBB, as a mechanism of coordination of actions in complex systems. Results: The article was prepared on the basis of literature from the researched area. The material was also prepared on the basis of interviews with practitioners. They have allowed for the preparation of template process models (Reference Models for selected action coordination methods in the supply chain. Conclusions: The result of the work is a prepared model as well as its description in the use of IDEF0. The presented model is a demonstrative model. The proposed reference model makes it possible to define the parameters of a selected mechanism of coordination of actions, and forms a basis for affecting the progression of the process through an analysis of values of identified parameters. The parameterization of elements constitutes the foundation for the monitoring of the process via 1 unambiguous identification of the object of monitoring and 2 analysis of different variants of the progression of the process.

  3. Microfabricated Reference Electrodes and their Biosensing Applications

    Directory of Open Access Journals (Sweden)

    M. Jamal Deen

    2010-03-01

    Full Text Available Over the past two decades, there has been an increasing trend towards miniaturization of both biological and chemical sensors and their integration with miniaturized sample pre-processing and analysis systems. These miniaturized lab-on-chip devices have several functional advantages including low cost, their ability to analyze smaller samples, faster analysis time, suitability for automation, and increased reliability and repeatability. Electrical based sensing methods that transduce biological or chemical signals into the electrical domain are a dominant part of the lab-on-chip devices. A vital part of any electrochemical sensing system is the reference electrode, which is a probe that is capable of measuring the potential on the solution side of an electrochemical interface. Research on miniaturization of this crucial component and analysis of the parameters that affect its performance, stability and lifetime, is sparse. In this paper, we present the basic electrochemistry and thermodynamics of these reference electrodes and illustrate the uses of reference electrodes in electrochemical and biological measurements. Different electrochemical systems that are used as reference electrodes will be presented, and an overview of some contemporary advances in electrode miniaturization and their performance will be provided.

  4. A Service-Oriented E-Commerce Reference Architecture

    OpenAIRE

    Aulkemeier, Fabian; Schramm, Milan; Iacob, Maria Eugenia; van Hillegersberg, Jos

    2016-01-01

    Electronic commerce (e-commerce) is getting more and more important in people's every day shopping routines. Vendors who want to establish an online channel besides their traditional retail practice have to integrate the two supply chains. The underlying information technology systems should be able to support the integration of the new and old processes. While reference models are a popular means in designing this type of systems, the existing reference models in the field of e-commerce only...

  5. Roaming Reference: Reinvigorating Reference through Point of Need Service

    Directory of Open Access Journals (Sweden)

    Kealin M. McCabe

    2011-11-01

    Full Text Available Roaming reference service was pursued as a way to address declining reference statistics. The service was staffed by librarians armed with iPads over a period of six months during the 2010-2011 academic year. Transactional statistics were collected in relation to query type (Research, Facilitative or Technology, location and approach (librarian to patron, patron to librarian or via chat widget. Overall, roaming reference resulted in an additional 228 reference questions, 67% (n=153 of which were research related. Two iterations of the service were implemented, roaming reference as a standalone service (Fall 2010 and roaming reference integrated with traditional reference desk duties (Winter 2011. The results demonstrate that although the Weller Library’s reference transactions are declining annually, they are not disappearing. For a roaming reference service to succeed, it must be a standalone service provided in addition to traditional reference services. The integration of the two reference models (roaming reference and reference desk resulted in a 56% decline in the total number of roaming reference questions from the previous term. The simple act of roaming has the potential to reinvigorate reference services as a whole, forcing librarians outside their comfort zones, allowing them to reach patrons at their point of need.

  6. Histological and reference system for the analysis of mouse intervertebral disc.

    Science.gov (United States)

    Tam, Vivian; Chan, Wilson C W; Leung, Victor Y L; Cheah, Kathryn S E; Cheung, Kenneth M C; Sakai, Daisuke; McCann, Matthew R; Bedore, Jake; Séguin, Cheryle A; Chan, Danny

    2018-01-01

    A new scoring system based on histo-morphology of mouse intervertebral disc (IVD) was established to assess changes in different mouse models of IVD degeneration and repair. IVDs from mouse strains of different ages, transgenic mice, or models of artificially induced IVD degeneration were assessed. Morphological features consistently observed in normal, and early/later stages of degeneration were categorized into a scoring system focused on nucleus pulposus (NP) and annulus fibrosus (AF) changes. "Normal NP" exhibited a highly cellularized cell mass that decreased with natural ageing and in disc degeneration. "Normal AF" consisted of distinct concentric lamellar structures, which was disrupted in severe degeneration. NP/AF clefts indicated more severe changes. Consistent scores were obtained between experienced and new users. Altogether, our scoring system effectively differentiated IVD changes in various strains of wild-type and genetically modified mice and in induced models of IVD degeneration, and is applicable from the post-natal stage to the aged mouse. This scoring tool and reference resource addresses a pressing need in the field for studying IVD changes and cross-study comparisons in mice, and facilitates a means to normalize mouse IVD assessment between different laboratories. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:233-243, 2018. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

  7. Digital Receiver Design for Transmitted Reference Ultra-Wideband Systems

    Directory of Open Access Journals (Sweden)

    Wang Yiyin

    2009-01-01

    Full Text Available Abstract A complete detection, channel estimation, synchronization, and equalization scheme for a transmitted reference (TR ultra-wideband (UWB system is proposed in this paper. The scheme is based on a data model which admits a moderate data rate and takes both the interframe interference (IFI and the intersymbol interference (ISI into consideration. Moreover, the bias caused by the interpulse interference (IPI in one frame is also taken into account. Based on the analysis of the stochastic properties of the received signals, several detectors are studied and evaluated. Furthermore, a data-aided two-stage synchronization strategy is proposed, which obtains sample-level timing in the range of one symbol at the first stage and then pursues symbol-level synchronization by looking for the header at the second stage. Three channel estimators are derived to achieve joint channel and timing estimates for the first stage, namely, the linear minimum mean square error (LMMSE estimator, the least squares (LS estimator, and the matched filter (MF. We check the performance of different combinations of channel estimation and equalization schemes and try to find the best combination, that is, the one providing a good tradeoff between complexity and performance.

  8. Digital Receiver Design for Transmitted Reference Ultra-Wideband Systems

    Directory of Open Access Journals (Sweden)

    Yiyin Wang

    2009-01-01

    Full Text Available A complete detection, channel estimation, synchronization, and equalization scheme for a transmitted reference (TR ultra-wideband (UWB system is proposed in this paper. The scheme is based on a data model which admits a moderate data rate and takes both the interframe interference (IFI and the intersymbol interference (ISI into consideration. Moreover, the bias caused by the interpulse interference (IPI in one frame is also taken into account. Based on the analysis of the stochastic properties of the received signals, several detectors are studied and evaluated. Furthermore, a data-aided two-stage synchronization strategy is proposed, which obtains sample-level timing in the range of one symbol at the first stage and then pursues symbol-level synchronization by looking for the header at the second stage. Three channel estimators are derived to achieve joint channel and timing estimates for the first stage, namely, the linear minimum mean square error (LMMSE estimator, the least squares (LS estimator, and the matched filter (MF. We check the performance of different combinations of channel estimation and equalization schemes and try to find the best combination, that is, the one providing a good tradeoff between complexity and performance.

  9. Reference spent fuel and its characteristics for the concept development of a deep geological disposal system

    Energy Technology Data Exchange (ETDEWEB)

    Kang, C. H.; Choi, J. W.; Ko, W. I.; Lee, Y. M.; Park, J. H.; Hwang, Y. S.; Kim, S. K.

    1997-09-01

    The total amount of spent fuel arisen from the nuclear power plant to be planned by 2010 at the basis of the long-term power development plan announced by MOTIE (Ministry of Trade, Industry and Energy Resource) in 1995 is estimated to derive the disposal capacity of a deep geological repository is derived. The reference spent fuel whose characteristics could be planned is selected by analysing the characteristic data such as initial enrichment, discharge burnup, geometry, dimension, gross weight, etc. Also isotopic concentration, radioactivity, decay heat, hazard index and radiation intensity of a reference spent fuel are quantitatively identified and summarized in order to apply in the concept developing works of a deep geological disposal system. (author). 12 refs., 24 tabs., 14 figs.

  10. Reference spent fuel and its characteristics for the concept development of a deep geological disposal system

    International Nuclear Information System (INIS)

    Kang, C. H.; Choi, J. W.; Ko, W. I.; Lee, Y. M.; Park, J. H.; Hwang, Y. S.; Kim, S. K.

    1997-09-01

    The total amount of spent fuel arisen from the nuclear power plant to be planned by 2010 at the basis of the long-term power development plan announced by MOTIE (Ministry of Trade, Industry and Energy Resource) in 1995 is estimated to derive the disposal capacity of a deep geological repository is derived. The reference spent fuel whose characteristics could be planned is selected by analysing the characteristic data such as initial enrichment, discharge burnup, geometry, dimension, gross weight, etc. Also isotopic concentration, radioactivity, decay heat, hazard index and radiation intensity of a reference spent fuel are quantitatively identified and summarized in order to apply in the concept developing works of a deep geological disposal system. (author). 12 refs., 24 tabs., 14 figs

  11. Effects of Darbepoetin Alfa with exercise in cancer patients undergoing chemotherapy: an explorative study

    DEFF Research Database (Denmark)

    Rørth, Mikael; Rich Madsen, Katrine; Burmølle, Stine Hvid

    2011-01-01

    improvement in cognitive and emotional functioning, and subjective daily well-being. Furthermore physical improvement and changes in QoL outcomes showed no significant differences between the study group and a reference group. A significant increase in the hemoglobin concentration (7.14–7.87 mmol/L, P...Fatigue is frequent in cancer patients undergoing chemotherapy. Erythropoietins (EPO) have shown well-documented effects on these patients, and administered in pharmacological doses, may reduce the need for transfusion of blood cells and improve quality of life (QoL). An explorative, descriptive......, non-randomised intervention study using semi-structured interviews was conducted with the aim to gain an insight into the effects and experiences associated with EPO treatment in combination with a structured 6-week physical exercise intervention. Sixteen cancer patients with evidence of disease, who...

  12. The disposal of Canada's nuclear fuel waste: comments on the postclosure assessment of a reference system

    International Nuclear Information System (INIS)

    Allan, C.J.; Goodwin, B.W.

    1996-07-01

    Canada, like other countries, is developing technology for disposal of its nuclear fuel waste , based on the concept of geological disposal in stable plutonic rock of the Canadian Shield. The choice of methods, materials, and designs for a disposal system will ultimately be made on the basis of safety, taking into account the characteristics of the specific site on which the facility is to be developed, costs and practicality. As part of its work in developing the technology for the disposal of Canada's nuclear fuel waste, AECL analyzed the performance of a hypothetical disposal facility that incorporates specific design choices for the engineered barriers and that assumes a specific geological setting. This system, comprising the disposal facility and the geological setting, and the results of the performance analysis, is described in an Environmental Impact Statement that AECL submitted in 1994 and in a Primary Reference for the EIS 'The Disposal of Canada's Nuclear Fuel Waste: Postclosure Assessment of a Reference System.' The performance analysis was not intended to be a general proof of the safety of disposal, but rather it presents a safety analysis of one specific system to illustrate the postclosure assessment methodology and to demonstrate that safety could be achieved for the system in question. Although the design of the disposal facility analyzed and the geological setting have specific features, the results obtained from the safety analysis can, however, be used to provide considerable insight into the performance of the various components that comprise the multibarrier geological disposal system. Moreover, the results can show how changes in the performance of specific components can affect the overall performance of the system. This report discusses these aspects of the postclosure analysis. (author)

  13. A Comparison Between the OSI Reference Model and the B-ISDN Protocol Reference Model

    DEFF Research Database (Denmark)

    Staalhagen, Lars

    1996-01-01

    This article aims at comparing the Open Systems Interconnection (OSI) Reference Model (RM) and the broadband integrated services digital network (B-ISDN) Protocol Reference Model (PRM). According to the International Telecommunications Union - Telecommunications Sector (ITU-T), the exact...... relationship between the lower layers of the OSI RM and the B-ISDN PRM is for further study. It is therefore the intention of this article to present some views on these relationships which hopefully could facilitate an interconnection between B-ISDN and data networks conforming to the OSI standards....

  14. Computer-assisted three-dimensional reconstruction of the corticospinal system as a reference for CT and MRI

    International Nuclear Information System (INIS)

    Buhmann, C.; Kretschmann, H.J.

    1998-01-01

    We present a three-dimensional (3D) anatomical computer-graphics model of the corticospinal system acquired from equidistant serial anatomical slices of six intracranially-fixed human brains. This model is part of a neuroanatomical reference system (NeuRef) which enables 3D visualization of the brain and shows the relationship of its components such as anatomical structures, functional fibre tracts and arteries. Sections through the models can be matched with corresponding CT or MR images. This allows the probable localisation of corticospinal fibres on CT or MRI. (orig.) (orig.)

  15. Reference gene validation for qPCR in rat carotid body during postnatal development

    Directory of Open Access Journals (Sweden)

    Carroll John L

    2011-10-01

    Full Text Available Abstract Background The carotid bodies are the main arterial oxygen chemoreceptors in mammals. Afferent neural output from the carotid bodies to brainstem respiratory and cardiovascular nuclei provides tonic input and mediates important protective responses to acute and chronic hypoxia. It is widely accepted that the selection of reference genes for mRNA normalization in quantitative real-time PCR must be validated for a given tissue and set of conditions. This is particularly important for studies in carotid body during early postnatal maturation as the arterial oxygen tension undergoes major changes from fetal to postnatal life, which may affect reference gene expression. In order to determine the most stable and suitable reference genes for the study of rat carotid body during development, six commonly used reference genes, β-actin, RPII (RNA polymerase II, PPIA (peptidyl-proyl-isomerase A, TBP (TATA-box binding protein, GAPDH, and 18s rRNA, were evaluated in two age groups (P0-1 and P14-16 under three environmental oxygen conditions (normoxia, chronic hypoxia and chronic hyperoxia using the three most commonly used software programs, geNorm, NormFinder and BestKeeper. Findings The three programs produced similar results but the reference gene rankings were not identical between programs or experimental conditions. Overall, 18s rRNA was the least stable reference gene for carotid body and, when hyperoxia and/or hypoxia conditions were included, actin was similarly unstable. Conclusions Reference or housekeeping gene expression for qPCR studies of carotid body during postnatal development may vary with developmental stage and environmental conditions. Selection of the best reference gene or combination of reference genes for carotid body development studies should take environmental conditions into account. Two commonly used reference genes, 18s rRNA and actin, may be unsuitable for studies of carotid body maturation, especially if the study

  16. Decision support systems in nuclear emergencies: A scenario-based comparison of domestic and reference tools

    International Nuclear Information System (INIS)

    Vamanu, D.; Slavnicu, S. D.; Slavnicu, E.; Vamanu, B.

    2004-01-01

    The article reports selective results of a comparison between RODOS - an emerging decision support system for the management of nuclear emergencies in Europe developed by an international research consortium under EEC aegis, and a resident software package developed and maintained for similar purposes at IFIN-HH, Bucharest. Reproducible similarity patterns obtained in the output data distributions provide for simple normalising procedures that may ensure convergent radiological assessments. When properly consolidated on a sufficient scenario casuistry, such procedures could lend a certain resilience to domestic decision support tools over the interim lead time required by the full implementation of RODOS, or other major league, internationally accepted reference systems. (authors)

  17. Electrical engineer's reference book

    CERN Document Server

    Laughton, M A

    1985-01-01

    Electrical Engineer's Reference Book, Fourteenth Edition focuses on electrical engineering. The book first discusses units, mathematics, and physical quantities, including the international unit system, physical properties, and electricity. The text also looks at network and control systems analysis. The book examines materials used in electrical engineering. Topics include conducting materials, superconductors, silicon, insulating materials, electrical steels, and soft irons and relay steels. The text underscores electrical metrology and instrumentation, steam-generating plants, turbines

  18. Understanding of advance care planning by family members of persons undergoing hemodialysis.

    Science.gov (United States)

    Calvin, Amy O; Engebretson, Joan C; Sardual, S Alexander

    2014-11-01

    The purpose of this qualitative descriptive study was to explore hemodialysis patients' family members' understanding of end-of-life decision-making processes. The project aimed to address (a) family members' constructions of advance care planning (ACP), including their roles and responsibilities, and (b) family members' perceptions of health care providers' roles and responsibilities in ACP. Eighteen family members of persons undergoing hemodialysis were recruited primarily from outpatient dialysis facilities and interviewed individually. Confirmed transcript data were analyzed, coded, and compared, and categories were established. Interpretations were validated throughout the interviews and peer debriefing sessions were used at a later stage in the analysis. The overarching construct identified was one of Protection. Family members protect patients by (a) Sharing Burdens, (b) Normalizing Life, and (c) Personalizing Care. Recommendations for future research include the need to explore ACP of persons undergoing hemodialysis who do not have a family support system. © The Author(s) 2013.

  19. Automatic control of the NMB level in general anaesthesia with a switching total system mass control strategy.

    Science.gov (United States)

    Teixeira, Miguel; Mendonça, Teresa; Rocha, Paula; Rabiço, Rui

    2014-12-01

    This paper presents a model based switching control strategy to drive the neuromuscular blockade (NMB) level of patients undergoing general anesthesia to a predefined reference. A single-input single-output Wiener system with only two parameters is used to model the effect of two different muscle relaxants, atracurium and rocuronium, and a switching controller is designed based on a bank of total system mass control laws. Each of such laws is tuned for an individual model from a bank chosen to represent the behavior of the whole population. The control law to be applied at each instant corresponds to the model whose NMB response is closer to the patient's response. Moreover a scheme to improve the reference tracking quality based on the analysis of the patient's response, as well as, a comparison between the switching strategy and the Extended Kalman Kilter (EKF) technique are presented. The results are illustrated by means of several simulations, where switching shows to provide good results, both in theory and in practice, with a desirable reference tracking. The reference tracking improvement technique is able to produce a better reference tracking. Also, this technique showed a better performance than the (EKF). Based on these results, the switching control strategy with a bank of total system mass control laws proved to be robust enough to be used as an automatic control system for the NMB level.

  20. Indicators of collapse in systems undergoing unsustainable growth.

    Science.gov (United States)

    Ridolfi, Luca; D'Odorico, Paolo; Laio, Francesco

    2015-02-01

    Unsustainable growth is typical of systems that rely on a finite pool of non-renewable resources that are tapped until they are depleted. The decrease in resource availability eventually leads these systems to a decline. Here we investigate the dynamics of systems that exhibit unsustainable growth and are prone to a collapse to an alternative ("degraded") state. For these systems the possible imminent occurrence of a collapse is difficult to avert because they keep growing as they approach the transition point. It is therefore important to identify some early warning signs that can be used to predict whether the system is approaching a critical and likely irreversible transition to an undesired and degraded state. This study evaluates whether existing theories of precursors of phase transitions based on the critical slowing down phenomenon are applicable as leading indicators of state shift in unsustainable growth dynamics. It is found that such indicators fail to serve as reliable early warning signs of the system's collapse.

  1. Physics of Non-Inertial Reference Frames

    International Nuclear Information System (INIS)

    Kamalov, Timur F.

    2010-01-01

    Physics of non-inertial reference frames is a generalizing of Newton's laws to any reference frames. It is the system of general axioms for classical and quantum mechanics. The first, Kinematics Principle reads: the kinematic state of a body free of forces conserves and equal in absolute value to an invariant of the observer's reference frame. The second, Dynamics Principle extended Newton's second law to non-inertial reference frames and also contains additional variables there are higher derivatives of coordinates. Dynamics Principle reads: a force induces a change in the kinematic state of the body and is proportional to the rate of its change. It is mean that if the kinematic invariant of the reference frame is n-th derivative with respect the time, then the dynamics of a body being affected by the force F is described by the 2n-th differential equation. The third, Statics Principle reads: the sum of all forces acting a body at rest is equal to zero.

  2. Willingness to undergo HIV testing in the Kintampo districts of Ghana.

    Science.gov (United States)

    Abokyi, L V; Zandoh, C; Mahama, E; Sulemana, A; Adda, R; Amenga-Etego, S; Baiden, F; Owusu-Agyei, S

    2014-03-01

    HIV testing is currently a major prevention intervention and remains an entry point to early treatment, care and support. Uptake is however low and alternative approaches are currently being adopted. An HIV module was incorporated into the routine survey of the Kintampo Health and Demographic Surveillance System (KHDSS) to assess the willingness of adults living in the Kintampo North and South districts to undergo HIV testing. The study was a descriptive cross-sectional household survey. Univariate and multivariate analysis were used to identify predictors of the willingness to undergo HIV testing. Respondents were community members aged 15 to 49 years and selected from randomly generated household listings from the KHDSS. A total of 11,604 respondents were interviewed, 10,982 (94.6%) of respondents had good general knowledge on HIV/AIDS. Among those with knowledge about HIV/AIDS, 10,819 (98.5%) indicated their willingness to get tested for HIV. Rural residents were more willing to undergo HIV testing than urban dwellers Odds ratio=1.42 (95% Confidence interval: 1.03, 1.96; P-value=0.031). Respondents with primary education were more likely to go for testing relative to those without any education OR=2.02 (95% CI: 0.87, 4.70; P-value=0.046). Expressed willingness to test for HIV is high in this population. Exploring community and population-based interventions to HIV testing and counseling could increase uptake of HIV testing services and should be considered. The underlying motivations need to be explored in order to translate willingness into actual testing.

  3. Specialised care in patients undergoing pancreatoduodenectomy

    NARCIS (Netherlands)

    Tol, J.A.M.G.

    2014-01-01

    This thesis studies the controversies in the management of patients with pancreatic cancer undergoing pancreatoduodenectomy and determines different factors that will improve this management and thereby the postoperative outcomes. The studies were performed in both the pre-, peri- and postoperative

  4. Speed Estimation of Induction Motor Using Model Reference Adaptive System with Kalman Filter

    Directory of Open Access Journals (Sweden)

    Pavel Brandstetter

    2013-01-01

    Full Text Available The paper deals with a speed estimation of the induction motor using observer with Model Reference Adaptive System and Kalman Filter. For simulation, Hardware in Loop Simulation method is used. The first part of the paper includes the mathematical description of the observer for the speed estimation of the induction motor. The second part describes Kalman filter. The third part describes Hardware in Loop Simulation method and its realization using multifunction card MF 624. In the last section of the paper, simulation results are shown for different changes of the induction motor speed which confirm high dynamic properties of the induction motor drive with sensorless control.

  5. Preprocedural High-Sensitivity Cardiac Troponin T and Clinical Outcomes in Patients With Stable Coronary Artery Disease Undergoing Elective Percutaneous Coronary Intervention.

    Science.gov (United States)

    Zanchin, Thomas; Räber, Lorenz; Koskinas, Konstantinos C; Piccolo, Raffaele; Jüni, Peter; Pilgrim, Thomas; Stortecky, Stefan; Khattab, Ahmed A; Wenaweser, Peter; Bloechlinger, Stefan; Moschovitis, Aris; Frenk, Andre; Moro, Christina; Meier, Bernhard; Fiedler, Georg M; Heg, Dik; Windecker, Stephan

    2016-06-01

    Cardiac troponin detected by new-generation, highly sensitive assays predicts clinical outcomes among patients with stable coronary artery disease (SCAD) treated medically. The prognostic value of baseline high-sensitivity cardiac troponin T (hs-cTnT) elevation in SCAD patients undergoing elective percutaneous coronary interventions is not well established. This study assessed the association of preprocedural levels of hs-cTnT with 1-year clinical outcomes among SCAD patients undergoing percutaneous coronary intervention. Between 2010 and 2014, 6974 consecutive patients were prospectively enrolled in the Bern Percutaneous Coronary Interventions Registry. Among patients with SCAD (n=2029), 527 (26%) had elevated preprocedural hs-cTnT above the upper reference limit of 14 ng/L. The primary end point, mortality within 1 year, occurred in 20 patients (1.4%) with normal hs-cTnT versus 39 patients (7.7%) with elevated baseline hs-cTnT (P<0.001). Patients with elevated hs-cTnT had increased risks of all-cause (hazard ratio 5.73; 95% confidence intervals 3.34-9.83; P<0.001) and cardiac mortality (hazard ratio 4.68; 95% confidence interval 2.12-10.31; P<0.001). Preprocedural hs-TnT elevation remained an independent predictor of 1-year mortality after adjustment for relevant risk factors, including age, sex, and renal failure (adjusted hazard ratio 2.08; 95% confidence interval 1.10-3.92; P=0.024). A graded mortality risk was observed across higher tertiles of elevated preprocedural hs-cTnT, but not among patients with hs-cTnT below the upper reference limit. Preprocedural elevation of hs-cTnT is observed in one fourth of SCAD patients undergoing elective percutaneous coronary intervention. Increased levels of preprocedural hs-cTnT are proportionally related to the risk of death and emerged as independent predictors of all-cause mortality within 1 year. URL: http://www.clinicaltrials.gov. Unique identifier: NCT02241291. © 2016 American Heart Association, Inc.

  6. Analysis and comparison of NoSQL databases with an introduction to consistent references in big data storage systems

    Science.gov (United States)

    Dziedzic, Adam; Mulawka, Jan

    2014-11-01

    NoSQL is a new approach to data storage and manipulation. The aim of this paper is to gain more insight into NoSQL databases, as we are still in the early stages of understanding when to use them and how to use them in an appropriate way. In this submission descriptions of selected NoSQL databases are presented. Each of the databases is analysed with primary focus on its data model, data access, architecture and practical usage in real applications. Furthemore, the NoSQL databases are compared in fields of data references. The relational databases offer foreign keys, whereas NoSQL databases provide us with limited references. An intermediate model between graph theory and relational algebra which can address the problem should be created. Finally, the proposal of a new approach to the problem of inconsistent references in Big Data storage systems is introduced.

  7. Significant vestibular system impairment is common in a cohort of elderly patients referred for assessment of falls risk.

    Science.gov (United States)

    Jacobson, Gary P; McCaslin, Devin L; Grantham, Sarah L; Piker, Erin G

    2008-01-01

    Falls in elderly patients are associated with morbidity, mortality, and cost to the healthcare system. The development of falls risk assessment programs have represented a method of responding to what is known about injurious falls. The multidimensional assessments involve the comparison against normative data of a patient's performance on metrics known to influence the likelihood of future falls. The factors assessed usually include falls and medication history, measures of mentation, depression, orthostatic hypotension, simple or choice reaction time, gait stability, postural stability, and the integrity of the patient's vision, somesthetic, and vestibular senses. This investigation was conducted to measure the proportion of patients referred for falls risk assessment who have evidence of vestibular system impairment. Qualitative, retrospective review of data collected from 2003 to 2007. The cohort was 185 consecutive patients referred for multidimensional assessments of falls risk. Patients underwent quantitative assessments of peripheral and central vestibular system function consisting of electro- or videonystagmography (i.e., ENG/VNG), and sinusoidal harmonic acceleration testing. Results of these tests were compared to normative data. We found that 73% of the sample who underwent vestibular system assessment had quantitative evidence of either peripheral or central vestibular system impairment. Our results suggest that quantitative assessments of the vestibulo-ocular reflex should be conducted on patients who are evaluated for falls risk. These examinations should include at least caloric testing and, where available, rotational testing.

  8. Reference Pricing with Endogenous or Exogenous Payment Limits: Impacts on Insurer and Consumer Spending.

    Science.gov (United States)

    Brown, Timothy T; Robinson, James C

    2016-06-01

    Reference pricing (RP) theories predict different outcomes when reference prices are fixed (exogenous) versus being a function of market prices (MPs) (endogenous). Exogenous RP results in MPs at both high-price and low-price firms converging towards the reference price from above and below, respectively. Endogenous RP results in MPs at both high-price and low-price firms decreasing, with low-price firms acting strategically to decrease the reference price in order to gain market share. We extend these models to a hospital context focusing on insurer and consumer payments. Under exogenous RP, insurer and consumer payments to low-price hospitals increase, and insurer payments to high-price hospitals decrease, but predictions regarding consumer payments are ambiguous for high-price hospitals. Under endogenous RP, insurer payments to high-price and low-price hospitals decrease, and consumer payments to low-price hospitals decrease, but predictions regarding consumer payments are ambiguous for high-price hospitals. We test these predictions with difference-in-differences specifications using 2008-2013 data on patients undergoing joint replacement. For 2 years following RP implementation, insurer payments to high-price and low-price hospitals moved downward, consistent with endogenous RP. However, when the reference price was not reset to account for changes in MPs, insurer payments to low-price hospitals reverted to pre-implementation levels, consistent with exogenous RP. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

  9. Subject Reference Lists Produced by Computer

    Directory of Open Access Journals (Sweden)

    Ching-chih Chen

    1968-08-01

    Full Text Available A system developed to produce fourteen subject reference lists by IBM 360/75 is described in detail. The computerized system has many advantages over conventional manual procedures. The feedback from students and other users is discussed, and some analysis of cost is included.

  10. Computer-assisted three-dimensional reconstruction of the corticospinal system as a reference for CT and MRI

    Energy Technology Data Exchange (ETDEWEB)

    Buhmann, C. [Department of Neuroanatomy, Hannover Medical School (Germany)]|[University Hospital Eppendorf, Hamburg (Germany); Kretschmann, H.J. [Department of Neuroanatomy, Hannover Medical School (Germany)

    1998-09-01

    We present a three-dimensional (3D) anatomical computer-graphics model of the corticospinal system acquired from equidistant serial anatomical slices of six intracranially-fixed human brains. This model is part of a neuroanatomical reference system (NeuRef) which enables 3D visualization of the brain and shows the relationship of its components such as anatomical structures, functional fibre tracts and arteries. Sections through the models can be matched with corresponding CT or MR images. This allows the probable localisation of corticospinal fibres on CT or MRI. (orig.) (orig.) With 18 figs., 3 tabs., 40 refs.

  11. Aspirin in patients undergoing noncardiac surgery

    DEFF Research Database (Denmark)

    Devereaux, P J; Mrkobrada, Marko; Sessler, Daniel I

    2014-01-01

    BACKGROUND: There is substantial variability in the perioperative administration of aspirin in patients undergoing noncardiac surgery, both among patients who are already on an aspirin regimen and among those who are not. METHODS: Using a 2-by-2 factorial trial design, we randomly assigned 10......,010 patients who were preparing to undergo noncardiac surgery and were at risk for vascular complications to receive aspirin or placebo and clonidine or placebo. The results of the aspirin trial are reported here. The patients were stratified according to whether they had not been taking aspirin before...... the study (initiation stratum, with 5628 patients) or they were already on an aspirin regimen (continuation stratum, with 4382 patients). Patients started taking aspirin (at a dose of 200 mg) or placebo just before surgery and continued it daily (at a dose of 100 mg) for 30 days in the initiation stratum...

  12. Intraoperative Ultrasound in Patients Undergoing Transsphenoidal Surgery for Pituitary Adenoma: Systematic Review [corrected].

    Science.gov (United States)

    Marcus, Hani J; Vercauteren, Tom; Ourselin, Sebastien; Dorward, Neil L

    2017-10-01

    Transsphenoidal surgery is the gold standard for pituitary adenoma resection. However, despite advances in microsurgical and endoscopic techniques, some pituitary adenomas can be challenging to cure. We sought to determine whether, in patients undergoing transsphenoidal surgery for pituitary adenoma, intraoperative ultrasound is a safe and effective technologic adjunct. The PubMed database was searched between January 1996 and January 2016 to identify relevant publications that 1) featured patients undergoing transsphenoidal surgery for pituitary adenoma, 2) used intraoperative ultrasound, and 3) reported on safety or effectiveness. Reference lists were also checked, and expert opinions were sought to identify further publications. Ultimately, 10 studies were included, comprising 1 cohort study, 7 case series, and 2 case reports. One study reported their prototype probe malfunctioned, leading to false-positive results in 2 cases, and another study' prototype probe was too large to safely enter the sphenoid sinus in 2 cases. Otherwise, no safety issues directly related to use of intraoperative ultrasound were reported. In the only comparative study, remission occurred in 89.7% (61/68) of patients with Cushing disease in whom intraoperative ultrasound was used, compared with 83.8% (57/68) in whom it was not. All studies reported that surgeons anecdotally found intraoperative ultrasound helpful. Although there is limited and low-quality evidence available, the use of intraoperative ultrasound appears to be a safe and effective technologic adjunct to transsphenoidal surgery for pituitary adenoma. Advances in ultrasound technology may allow for more widespread use of such devices. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Reproducibility of the sella turcica landmark in three dimensions using a sella turcica-specific reference system

    International Nuclear Information System (INIS)

    Pittayapat, Pisha; Jacobs, Reinhilde; Odri, Guillaume A.; De Faria Vasconcelos, Karla; Willems, Guy; Olszewski, Raphael

    2015-01-01

    This study was performed to assess the reproducibility of identifying the sella turcica landmark in a three-dimensional (3D) model by using a new sella-specific landmark reference system. Thirty-two cone-beam computed tomographic scans (3D Accuitomo 170, J. Morita, Kyoto, Japan) were retrospectively collected. The 3D data were exported into the Digital Imaging and Communications in Medicine standard and then imported into the Maxilim software (Medicim NV, Sint-Niklaas, Belgium) to create 3D surface models. Five observers identified four osseous landmarks in order to create the reference frame and then identified two sella landmarks. The x, y, and z coordinates of each landmark were exported. The observations were repeated after four weeks. Statistical analysis was performed using the multiple paired t-test with Bonferroni correction (intraobserver precision: p<0.005, interobserver precision: p<0.0011). The intraobserver mean precision of all landmarks was <1 mm. Significant differences were found when comparing the intraobserver precision of each observer (p<0.005). For the sella landmarks, the intraobserver mean precision ranged from 0.43±0.34 mm to 0.51±0.46 mm. The intraobserver reproducibility was generally good. The overall interobserver mean precision was <1 mm. Significant differences between each pair of observers for all anatomical landmarks were found (p<0.0011). The interobserver reproducibility of sella landmarks was good, with >50% precision in locating the landmark within 1 mm. A newly developed reference system offers high precision and reproducibility for sella turcica identification in a 3D model without being based on two-dimensional images derived from 3D data.

  14. Reproducibility of the sella turcica landmark in three dimensions using a sella turcica-specific reference system

    Energy Technology Data Exchange (ETDEWEB)

    Pittayapat, Pisha; Jacobs, Reinhilde [University Hospitals Leuven, University of Leuven, Leuven (Belgium); Odri, Guillaume A. [Service de Chirurgie Orthopedique et Traumatologique, Centre Hospitalier Regional d' Orleans, Orleans Cedex2 (France); De Faria Vasconcelos, Karla [Dept. of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, University of Campinas, Sao Paulo (Brazil); Willems, Guy [Dept. of Oral Health Sciences, Orthodontics, KU Leuven and Dentistry, University Hospitals Leuven, University of Leuven, Leuven (Belgium); Olszewski, Raphael [Dept. of Oral and Maxillofacial Surgery, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, Brussels (Belgium)

    2015-03-15

    This study was performed to assess the reproducibility of identifying the sella turcica landmark in a three-dimensional (3D) model by using a new sella-specific landmark reference system. Thirty-two cone-beam computed tomographic scans (3D Accuitomo 170, J. Morita, Kyoto, Japan) were retrospectively collected. The 3D data were exported into the Digital Imaging and Communications in Medicine standard and then imported into the Maxilim software (Medicim NV, Sint-Niklaas, Belgium) to create 3D surface models. Five observers identified four osseous landmarks in order to create the reference frame and then identified two sella landmarks. The x, y, and z coordinates of each landmark were exported. The observations were repeated after four weeks. Statistical analysis was performed using the multiple paired t-test with Bonferroni correction (intraobserver precision: p<0.005, interobserver precision: p<0.0011). The intraobserver mean precision of all landmarks was <1 mm. Significant differences were found when comparing the intraobserver precision of each observer (p<0.005). For the sella landmarks, the intraobserver mean precision ranged from 0.43±0.34 mm to 0.51±0.46 mm. The intraobserver reproducibility was generally good. The overall interobserver mean precision was <1 mm. Significant differences between each pair of observers for all anatomical landmarks were found (p<0.0011). The interobserver reproducibility of sella landmarks was good, with >50% precision in locating the landmark within 1 mm. A newly developed reference system offers high precision and reproducibility for sella turcica identification in a 3D model without being based on two-dimensional images derived from 3D data.

  15. Restoration of the orbital aesthetic subunit with the thoracodorsal artery system of flaps in patients undergoing radiation therapy.

    Science.gov (United States)

    Chanowski, Eric J P; Casper, Keith A; Eisbruch, Avraham; Heth, Jason A; Marentette, Lawrence J; Prince, Mark E; Moyer, Jeffrey S; Chepeha, Douglas B

    2013-10-01

    Objectives To demonstrate the advantages of the thoracodorsal artery scapular tip autogenous transplant (Tdast) for patients requiring restoration of the orbital aesthetic subunit. Design Prospective case series. Setting Tertiary center. Participants Ten patients (M:F,6:4) with a mean age of 56 years (range, 21 to 78 years) underwent restoration of the orbital aesthetic subunit and radiation therapy between 2001 and 2008. Main Outcome Measures The two reconstructive advantages of the thoracodorsal artery system of flaps for orbital reconstruction are a long pedicle and the suitability of the scapula tip to meet the three-dimensional requirements of the orbit. Patients were assessed 1 year or more after treatment for cosmetic outcome, work status, and socialization. Results Eight of 10 patients benefited from the three-dimensional nature of the scapula tip bone and 7 of 10 avoided vein grafting. Four of five evaluable patients reported "frequently" socializing outside their home. Four of five evaluable patients working before undergoing their treatment were able to return to work posttreatment. Seven of nine patients with postoperative photographs had minimal or no facial contour deformity. Conclusions The Tdast can restore orbital contour without osteotomy, and the thoracodorsal artery system of flaps has a long vascular pedicle that reduces vein grafting. Patients have an acceptable cosmetic result and return to preoperative work status and socialization.

  16. Preoperative autologous plateletpheresis in patients undergoing open heart surgery.

    OpenAIRE

    Tomar Akhlesh; Tempe Deepak; Banerjee A; Hegde R; Cooper A; Khanna S

    2003-01-01

    Blood conservation is an important aspect of care provided to the patients undergoing cardiac operations with cardiopulmonary bypass (CPB). It is even more important in patients with anticipated prolonged CPB, redo cardiac surgery, patients having negative blood group and in patients undergoing emergency cardiac surgery. In prolonged CPB the blood is subjected to more destruction of important coagulation factors, in redo surgery the separation of adhesions leads to increased bleeding and diff...

  17. A system for environmental protection. Reference dose models for fauna and flora

    International Nuclear Information System (INIS)

    Pentreath, R.J.; Woodhead, D.S.

    2000-01-01

    Ideas have already been published on how the current problems relating to environmental protection could be explicitly addressed. One of the basic cornerstones of the proposed system is that of the use of reference dose models for fauna and flora, in a manner analogous to those used for the human species. The concept is that, for a number of both aquatic and terrestrial fauna and flora types, 'reference' dose models, and dose per unit (internal and external) exposure tables, could be compiled. These would then be used to draw broad conclusions on the likely effects for such organisms in relation to three broad environment end points of concern: life shortening; impairment of reproductive capacity; and scorable, cytogenetic damage. The level of complexity of the dose models needs to be commensurate with the morphological complexity of the modelled organism, its size, and the data bases which are either available or could be reasonably obtained. The most basic models considered are either solid ellipsoids or spheres, with fixed dimensions. Secondary models contain internal, but relatively simple geometric features representative of those key organs or tissues for which more precise estimates of dose are required. Their level of complexity is also a function of different internal and external sources of radiation, and expected differences in radiosensitivities. Tertiary models -of greater complexity- are only considered to be of value for higher vertebrates. The potential derivation and use of all three sets of models is briefly discussed. (author)

  18. The Evaluation of Relationship between Sexual Self-concept and Sexual Dysfunction in Individuals Undergoing Methadone Maintenance Treatment

    Science.gov (United States)

    Rajabizadeh, Ghodratolah; Yazdanpanah, Fatemeh; Ramezani, Mohammad Arash

    2017-01-01

    Background The present study was conducted with the aim of designing a causal model for the evaluation of sexual dysfunctions based on the variables of methadone dosage and sexual self-concept among individuals undergoing methadone maintenance treatment (MMT). Methods The study population of the present study consisted of married men of 20 to 45 years of age with sexual ýrelations and undergoing MMT for a minimum of 8 weeks referring to all MMT clinics of Kerman, Iran, in ýý2015-2016. ýThe subjects were selected through multi-stage cluster sampling (n = 250). Data were collected using the General Health Questionnaire (GHQ-28), Multi-Dimensional Sexual Self-concept Questionnaire (MSSQ), and Internal Index for Erectile Function (IIEF). Data were analyzed using path analysis method and Pearson correlation coefficient. The suggested model was evaluated using structural equation model (SEM), and indirect relationships were assessed using Bootstrap method. Findings The suggested model showed acceptable fitness with the data, and all routes, except methadone use route, to sexual function were significant. The result of the multiple ýindirect route showed that sexual function had a significant relationship with methadone use through ýsexual self-concept. In total, 60% of variance in sexual dysfunction was explained using the variables of the suggested model. Conclusion Further studies are suggested to be conducted regarding psychological factors effective on the sexual dysfunctions among individuals undergoing MMT, such as sexual self-concept. Moreover, more detailed evaluation of each subscale of positive and negative sexual self-concept is recommended to assess the psychological causes of sexual dysfunctions in these individuals and design psychological, behavioral, and cognitive-behavioral treatment interventions for them. PMID:29299211

  19. The Evaluation of Relationship between Sexual Self-concept and Sexual Dysfunction in Individuals Undergoing Methadone Maintenance Treatment.

    Science.gov (United States)

    Rajabizadeh, Ghodratolah; Yazdanpanah, Fatemeh; Ramezani, Mohammad Arash

    2017-04-01

    The present study was conducted with the aim of designing a causal model for the evaluation of sexual dysfunctions based on the variables of methadone dosage and sexual self-concept among individuals undergoing methadone maintenance treatment (MMT). The study population of the present study consisted of married men of 20 to 45 years of age with sexual ýrelations and undergoing MMT for a minimum of 8 weeks referring to all MMT clinics of Kerman, Iran, in ýý2015-2016. ýThe subjects were selected through multi-stage cluster sampling (n = 250). Data were collected using the General Health Questionnaire (GHQ-28), Multi-Dimensional Sexual Self-concept Questionnaire (MSSQ), and Internal Index for Erectile Function (IIEF). Data were analyzed using path analysis method and Pearson correlation coefficient. The suggested model was evaluated using structural equation model (SEM), and indirect relationships were assessed using Bootstrap method. The suggested model showed acceptable fitness with the data, and all routes, except methadone use route, to sexual function were significant. The result of the multiple ýindirect route showed that sexual function had a significant relationship with methadone use through ýsexual self-concept. In total, 60% of variance in sexual dysfunction was explained using the variables of the suggested model. Further studies are suggested to be conducted regarding psychological factors effective on the sexual dysfunctions among individuals undergoing MMT, such as sexual self-concept. Moreover, more detailed evaluation of each subscale of positive and negative sexual self-concept is recommended to assess the psychological causes of sexual dysfunctions in these individuals and design psychological, behavioral, and cognitive-behavioral treatment interventions for them.

  20. An improved synchronous reference frame phase-locked loop for stand-alone variable speed constant frequency power generation systems

    DEFF Research Database (Denmark)

    Liu, Yi; Xu, Wei; Ke, Longzhang

    2017-01-01

    The phase-locked loop (PLL) based on conventional synchronous reference frame, i.e. dqPLL, is usually employed in grid-connected variable speed constant frequency (VSCF) power generation systems (PGSs). However, the voltage amplitude drop of stand-alone PGSs is often greater than that of the grid...

  1. Investigating the motives of patients with knee OA undergoing a TKR

    DEFF Research Database (Denmark)

    Traumer, Line; Sørensen, Erik Elgaard; Kusk, Kathrine Hoffmann

    2018-01-01

    , a qualitatively assessment of what actually affects the patient's decision to undergo TKR would be important. Therefore, the purpose of this study was to investigate the motives of patients with knee OA choosing to undergo TKR and to explore the factors considered important during their decision?making process...... was a legitimate argument among patients. The prospect of avoiding taking high doses of pain?relieving medication and hearing positive experiences of others who had undergone TKR motivated patients to undergo TKR. However, negative experiences of others were neglected. Conclusions Patients' decision?making process...... revealed that the interaction between doctor and patient emerged as a factor highly influential on patients' decision?making process with patients choosing the treatment option suggested by the doctor. Using x?rays, revealing no cartilage between the bones, as a reason for choosing to undergo TKR...

  2. Coping strategies used by hospitalized children with cancer undergoing chemotherapy.

    Science.gov (United States)

    Sposito, Amanda Mota Pacciulio; Silva-Rodrigues, Fernanda Machado; Sparapani, Valéria de Cássia; Pfeifer, Luzia Iara; de Lima, Regina Aparecida Garcia; Nascimento, Lucila Castanheira

    2015-03-01

    To analyze coping strategies used by children with cancer undergoing chemotherapy during hospitalization. This was an exploratory study to analyze qualitative data using an inductive thematic analysis. Semistructured interviews using puppets were conducted with 10 children with cancer, between 7 and 12 years old, who were hospitalized and undergoing chemotherapy. The coping strategies to deal with chemotherapy were: understanding the need for chemotherapy; finding relief for the chemotherapy's side effects and pain; seeking pleasure in nourishment; engaging in entertaining activities and having fun; keeping the hope of cure alive; and finding support in religion. Children with cancer undergoing chemotherapy need to cope with hospitalizations, pain, medication side effects, idle time, and uncertainty regarding the success of treatment. These challenges motivated children to develop their own coping strategies, which were effective while undergoing chemotherapy. By gaining knowledge and further understanding about valid coping strategies during chemotherapy treatment, health professionals can mobilize personal and material resources from the children, health teams, and institutions aiming to potentiate the use of these strategies to make treatments the least traumatic. © 2015 Sigma Theta Tau International.

  3. Assessment of the periodontal health status in patients undergoing orthodontic treatment with fixed appliances and Invisalign system: A meta-analysis.

    Science.gov (United States)

    Lu, Haili; Tang, Haifang; Zhou, Tian; Kang, Na

    2018-03-01

    At present, many scholars have studied the periodontal health status of patients undergoing orthodontic treatment with fixed appliances and invisalign. However, those results are inconsistent. Therefore, we conducted this meta-analysis, and then provide reference for clinical treatment. Most databases, such as the Cochrane Library, EMBASE, PubMed, Medline, Chinese Biomedical Literature Database, CNKI, and Wan Fang Data were retrieved for related articles from the establishment of the database to October 2017. Meanwhile, we also searched the references of the related literatures manually, in order to increase the included literatures. Two researchers screened the related literatures according to the inclusion criteria and exclusion criteria. Stata 12.0 software was used for data analysis, and results are estimated by odds ratio (OR) and 95% confidence interval (CI). Finally, 7 articles, including 368 patients, were included into our meta-analysis. Meta-analysis results showed that there was no statistically significant difference of gingival index (GI) and sulcus probing depth (SPD) status between the invisalign group and the control group, including at 1, 3, and 6 months (all P > .05). When compared with the control group, the invisalign group presented a lower plaque index (PLI) and sulcus bleeding index (SBI) status at 1 month (OR = -0.53, 95% CI: -0.89 to -0.18; OR = -0.44, 95% CI: -0.70 to -0.19, respectively), 3 months (OR = -0.69, 95% CI: -1.12 to -0.27; OR = -0.49, 95% CI: -0.93 to -0.05, respectively), and 6 months (OR = -0.91, 95% CI: -1.47 to -0.35; OR = -0.40, 95% CI: -0.63 to -0.07, respectively). Subgroup analysis showed that the SPD status was lower in the invisalign group at 6 months when measured the teeth using Ramfjord index (OR = -0.74, 95% CI: -1.35 to -0.12). However, there was no statistically significant difference between the 2 groups when using other measure methods (OR = 0.12, 95% CI: -0.26 to 0.17). Our

  4. PVWatts Version 1 Technical Reference

    Energy Technology Data Exchange (ETDEWEB)

    Dobos, A. P.

    2013-10-01

    The NREL PVWatts(TM) calculator is a web application developed by the National Renewable Energy Laboratory (NREL) that estimates the electricity production of a grid-connected photovoltaic system based on a few simple inputs. PVWatts combines a number of sub-models to predict overall system performance, and makes several hidden assumptions about performance parameters. This technical reference details the individual sub-models, documents assumptions and hidden parameters, and explains the sequence of calculations that yield the final system performance estimation.

  5. Sizewell 'B' PWR reference design

    International Nuclear Information System (INIS)

    1982-04-01

    The reference design for a PWR power station to be constructed as Sizewell 'B' is presented in 3 volumes containing 14 chapters and in a volume of drawings. The report describes the proposed design and provides the basis upon which the safety case and the Pre-Construction Safety Report have been prepared. The station is based on a 3425MWt Westinghouse PWR providing steam to two turbine generators each of 600 MW. The layout and many of the systems are based on the SNUPPS design for Callaway which has been chosen as the US reference plant for the project. (U.K.)

  6. Electronics engineer's reference book

    CERN Document Server

    Mazda, F F

    1989-01-01

    Electronics Engineer's Reference Book, Sixth Edition is a five-part book that begins with a synopsis of mathematical and electrical techniques used in the analysis of electronic systems. Part II covers physical phenomena, such as electricity, light, and radiation, often met with in electronic systems. Part III contains chapters on basic electronic components and materials, the building blocks of any electronic design. Part IV highlights electronic circuit design and instrumentation. The last part shows the application areas of electronics such as radar and computers.

  7. Prediction of Change in Prescription Ingredient Costs and Co-payment Rates under a Reference Pricing System in South Korea.

    Science.gov (United States)

    Heo, Ji Haeng; Rascati, Karen L; Lee, Eui-Kyung

    2017-05-01

    The reference pricing system (RPS) establishes reference prices within interchangeable reference groupings. For drugs priced higher than the reference point, patients pay the difference between the reference price and the total price. To predict potential changes in prescription ingredient costs and co-payment rates after implementation of an RPS in South Korea. Korean National Health Insurance claims data were used as a baseline to develop possible RPS models. Five components of a potential RPS policy were varied: reference groupings, reference pricing methods, co-pay reduction programs, manufacturer price reductions, and increased drug substitutions. The potential changes for prescription ingredient costs and co-payment rates were predicted for the various scenarios. It was predicted that transferring the difference (total price minus reference price) from the insurer to patients would reduce ingredient costs from 1.4% to 22.8% for the third-party payer (government), but patient co-payment rates would increase from a baseline of 20.4% to 22.0% using chemical groupings and to 25.0% using therapeutic groupings. Savings rates in prescription ingredient costs (government and patient combined) were predicted to range from 1.6% to 13.7% depending on various scenarios. Although the co-payment rate would increase, a 15% price reduction by manufacturers coupled with a substitution rate of 30% would result in a decrease in the co-payment amount (change in absolute dollars vs. change in rates). Our models predicted that the implementation of RPS in South Korea would lead to savings in ingredient costs for the third-party payer and co-payments for patients with potential scenarios. Copyright © 2017 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  8. Reference Device-Assisted Adaptive Location Fingerprinting

    Directory of Open Access Journals (Sweden)

    Dongjin Wu

    2016-06-01

    Full Text Available Location fingerprinting suffers in dynamic environments and needs recalibration from time to time to maintain system performance. This paper proposes an adaptive approach for location fingerprinting. Based on real-time received signal strength indicator (RSSI samples measured by a group of reference devices, the approach applies a modified Universal Kriging (UK interpolant to estimate adaptive temporal and environmental radio maps. The modified UK can take the spatial distribution characteristics of RSSI into account. In addition, the issue of device heterogeneity caused by multiple reference devices is further addressed. To compensate the measuring differences of heterogeneous reference devices, differential RSSI metric is employed. Extensive experiments were conducted in an indoor field and the results demonstrate that the proposed approach not only adapts to dynamic environments and the situation of changing APs’ positions, but it is also robust toward measuring differences of heterogeneous reference devices.

  9. Changes in T-cell count in patients undergoing radiotherapy. With particular reference to preoperative irradiation for gastric carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Makino, K; Sato, S [Tokyo Medical Coll. (Japan)

    1980-01-01

    To know changes in immunological competence of T-cells induced by radiotherapy, T-cells in peripheral blood of patients who underwent radiotherapy were observed before, during, and 6 months after the irradiation. The subjects were 69 patients having malignant tumors including 20 with gastric cancer, 15 with breast cancer, and 9 with colon cancer. 200 rad of an exposure dose was irradiated for successive 5 to 6 days. A total of exposure doses ranged from 2,000 to 10,000 rad. T-cell count decreased markedly until exposure doses reached 3,000 rad, but its decrease was mild after exposure doses were over 3,000 rad. T-cell count decreased slightly in patients whose head and neck were irradiated, but it decreased markedly in patients whose thorax and abdomen were irradiated. Therefore, it was thought that there was a relationship between exposed sites and the decrease in T-cell count. T-cell count decreased markedly when irradiation field was wide. The smaller exposure doses were, the earlier the recovery of T-cell were. T-cells irradiated with over 7,000 rad did not recover within 6 months after the irradiation. The recovery of T-cells in patients with gastric cancer who did not undergo gastrectomy was markedly worse than that in patients who had gastrectomy. Patterns of changes in T-cell count were divided into 4 (ascending curve, U-type curve, flat curve, and descending curve), and prognosis of patients were discussed. There was a clear difference in prognosis of patients among four patterns.

  10. Analysis of the Reference Systems of Modern Selenographic Systems

    Science.gov (United States)

    Nefedyev, Yuri; Petrova, Natalia; Andreev, Alexey; Demina, Natalya

    2016-07-01

    In this work analysis of the reference systems of modern selenographic systems was made. The center of the Moon's mass position relative to its center of figure was determined from the data of "Clementine" and "Kaguya" missions and "ULCN" and "KSC-1162" catalogues. The knowledge of the Moon's center of mass position relative to its center of figure is important for researches of the lunar origin, structure and evolution and in terms of precision solutions circumlunar navigation tasks. At the present this task is the most relevant and demanded for cosmic lunar missions.The expansions by spherical harmonics N=5 degree and order of the lunar function h (λ, β) using the package ASNI USTU were executed. Module of the expansion of the local area to surfaces to full sphere was used. The parameters of cosmic missions are given for comparison (SAI; Bills, Ferrari). The normalized coefficients from expansions for eight sources of hypsometric information are obtained: "Clementine" (N=40), "KSC-1162" (N=5), "Kiev" (N=5), "SAI" (N=10; Chuikova (1975)), "Bills, Ferrari", "Kaguya" (Selena, Japan mission), "ULCN" (The Unified Lunar Control Network 2005). The displacements of the lunar center of figure relative to the lunar center of the mass were defined from equations (Chuikova (1975)): Δ ξ = C_{11} √{3}, Δ η= S_{11} √{3}, Δ ζ = C_{10} √{3}, where ξ is the axis directed towards the Earth, η is equatorial axis directed perpendicularly to ξ , ζ is rotation axis of the Moon, C_{11} , S_{11} , C_{10} are the normalized amplitudes of the harmonics of the first order expansion of the relief. After that we considered: - mathematical models in the form of expansions in spherical functions - methods for estimating the model parameters; - information technology data processing. As a model describing the behavior of the relief on the lunar sphere is used the expansion of the height in a series of spherical harmonics (Sagitov (1979)) in the form of a regression model

  11. Effects of Addition of Systemic Tramadol or Adjunct Tramadol to Lidocaine Used for Intravenous Regional Anesthesia in Patients Undergoing Hand Surgery

    Directory of Open Access Journals (Sweden)

    Abdulkadir Yektaş

    2016-01-01

    Full Text Available Intravenous regional anesthesia (IVRA is used in outpatient hand surgery as an easily applicable and cost-effective technique with clinical advantages. The present study aimed to investigate the effects of addition of systemic tramadol or adjunct tramadol to lidocaine for IVRA in patients undergoing hand surgery. American Society of Anesthesiologists (ASA I-II patients (n=60 who underwent hand surgery were included. For this purpose, only lidocaine (LDC, lidocaine+adjunct tramadol (LDC+TRA group, or lidocaine+systemic tramadol (LDC+SysTRA group was administered to the patients for IVRA and the groups were compared in terms of onset and recovery time of sensory and motor blocks, quality of anesthesia, and the degree of intraoperative and postoperative pain. The onset time of sensorial block was significantly shorter in the LDC+TRA group than that in the LDC+SysTRA group. The motor block recovery time was significantly shorter in the LDC+SysTRA group than that in the LDC+TRA and LDC groups. Administration of tramadol as an adjunct showed some clinical benefits by providing a shorter onset time of sensory and motor block, decreasing pain and analgesic requirement, and improving intraoperative conditions during IVRA. It was determined that systemic tramadol administration had no superiority.

  12. The Poisson alignment reference system implementation at the Advanced Photon Source

    International Nuclear Information System (INIS)

    Feier, I.

    1998-01-01

    The Poisson spot was established using a collimated laser beam from a 3-mW diode laser. It was monitored on a quadrant detector and found to be very sensitive to vibration and air disturbances. Therefore, for future work we strongly recommend a sealed vacuum tube in which the Poisson line may be propagated. A digital single-axis feedback system was employed to generate an straight line reference (SLR) on the X axis. Pointing accuracy was better than 8 ± 2 microns at a distance of 5 m. The digital system was found to be quite slow with a maximum bandwidth of 47 ± 9 Hz. Slow drifts were easily corrected but any vibration over 5 Hz was not. We recommend an analog proportional-integral-derivative (PID) controller for high bandwidth and smooth operation of the kinematic mirror. Although the Poisson alignment system (PAS) at the Advanced Photon Source is still in its infancy, it already shows great promise as a possible alignment system for the low-energy undulator test line (LEUTL). Since components such as wigglers and quadruples will initially be aligned with respect to each other using conventional means and mounted on some kind of rigid rail, the goal would be to align six to ten such rails over a distance of about 30 m. The PAS could be used to align these rails by mounting a sphere at the joint between two rails. These spheres would need to be in a vacuum pipe to eliminate the refractive effects of air. Each sphere would not be attached to either rail but instead to a flange connecting the vacuum pipes of each rail. Thus the whole line would be made up of straight, rigid segments that could be aligned by moving the joints. Each sphere would have its own detector, allowing the operators to actively monitor the position of each joint and therefore the overall alignment of the system

  13. Standardized Semantic Markup for Reference Terminologies, Thesauri and Coding Systems: Benefits for distributed E-Health Applications.

    Science.gov (United States)

    Hoelzer, Simon; Schweiger, Ralf K; Liu, Raymond; Rudolf, Dirk; Rieger, Joerg; Dudeck, Joachim

    2005-01-01

    With the introduction of the ICD-10 as the standard for diagnosis, the development of an electronic representation of its complete content, inherent semantics and coding rules is necessary. Our concept refers to current efforts of the CEN/TC 251 to establish a European standard for hierarchical classification systems in healthcare. We have developed an electronic representation of the ICD-10 with the extensible Markup Language (XML) that facilitates the integration in current information systems or coding software taking into account different languages and versions. In this context, XML offers a complete framework of related technologies and standard tools for processing that helps to develop interoperable applications.

  14. H.J. Bhabha: A case study of synchronous references

    International Nuclear Information System (INIS)

    Swarna, T.; Kalyane, V.L.; Prakasan, E.R.; Kumar, V.

    2006-01-01

    Quantitative analysis of the events of synchronous references in the research papers followed throughout the publishing career of an individual scientist revealed interesting highlights on the knowledge-generating-system. In the case study of Homi Jehangir Bhabha, the first quinquennium and fifth quinquennium of his research career had low self-references; the third quinquennium and the fourth quinquennium had moderate self-references; whereas the second quinquennium had the highest number of self-references. The two major clusters of self-references occurring during the second and third quinquenniums were indicators of active periods of knowledge-generating and faster communications. (author)

  15. Performance evaluation of the reference system for calibration of IPEN activities

    International Nuclear Information System (INIS)

    Martins, Elaine Wirney; Potiens, Maria da Penha A.

    2011-01-01

    The formation of good quality image in nuclear medicine services depends on several factors, including the radiopharmaceutical activity, which must be well determined by a specific apparatus, in perfect operating condition, called activimeter. Therefore, the establishment of a quality control program for measuring the radiopharmaceuticals radioactivity before being administered to the patient is crucial to the safe and effective use of the radiopharmaceuticals used in diagnostic and therapeutical procedures. Two activimeters, belonging by the Laboratorio de Calibracao do Instrumentos (LCI) of Instituto de Pesquisas Energeticas e Nucleares (IPEN), were evaluated: the secondary standard system NPL-CRC radionuclide calibrator, manufactured by Southern Scientific, and the work standard system CRC-15BT with traceability to National Institute of Standard and Technology (NIST). A set of standard sources of the radionuclides 1 '3 3 Ba, 57 Co and 137 Cs was used as reference to perform the quality control tests. The precision, accuracy and repeatability tests were in agreement with those established by the CNEN-NE 3.05 Brazilian standard, which recommends the variation limit of up to 10%, 5% and 5% respectively. The results obtained for the reproducibility tests presented a variation always below 1,5%, which means it is within the IEC 61674 international standard recommendation of up to 3%. Activimeters response regarding linearity showed concordance between the measured activities and the theoretical curve for both activimeters. (author)

  16. A Functional Reference Architecture for Aggregators

    DEFF Research Database (Denmark)

    Bondy, Daniel Esteban Morales; Heussen, Kai; Gehrke, Oliver

    2015-01-01

    Aggregators are considered to be a key enabling technology for harvesting power system services from distributed energy resources (DER). As a precondition for more widespread use of aggregators in power systems, methods for comparing and validating aggregator designs must be established. This paper...... proposes a functional reference architecture for aggregators to address this requirement....

  17. On the system of provision of ojsc "MMC 'Norilsk Nickel'" with interstate and State certified reference materials for quality control of cobalt, nickel, copper and promproducts

    Directory of Open Access Journals (Sweden)

    T. V. Shabelnikova

    2014-01-01

    Full Text Available In order to manage the quality of OJSC "MMC "Norilsk Nickel" products the Centre of Certified Reference Material Development has developed and is currently successfully implementing a system of operations provision with interstate and state certified reference materials of nickel, cobalt and copper composition. The system wholly corresponds to modern metrological requirements. The Centre of Reference Materials Development, fulfilling leading function in the field of state certified reference material production and supply to the Company's operations, aims its activity both at the development of new types of certified reference materials in the form of metals and at widening the range of synthetic oxide certified reference materials. Developed for the first time, metallic state certified reference materials of nickel, cobalt composition with certified mass fractions of oxygen, hydrogen, nitrogen, sulfur and carbon were put into practice of the Company's analytical services work. Certified reference material use provides the possibility to take into account requirements of some consumers to the quality of nickel and produce by OJSC "MMC "Norilsk Nickel" and also helps to raise competitive ability of the products on the world metals market. Over recent years the Centre fulfilled the work on the development, certification in established order, approval and entering into the State Register twenty five types of state certified reference materials. Certified reference materials are intended for fulfillment of the analysis of chemical composition of nickel, cobalt and copper in terms of their conformity with both national and international standards.

  18. The derivation of the general form of kinematics with the universal reference system

    Directory of Open Access Journals (Sweden)

    Karol Szostek

    2018-03-01

    Full Text Available In the article, the whole class of time and position transformations was derived. These transformations were derived based on the analysis of the Michelson-Morley experiment and its improved version, that is the Kennedy-Thorndike experiment. It is possible to derive a different kinematics of bodies based on each of these transformations. In this way, we demonstrated that the Special Theory of Relativity is not the only theory explaining the results of experiments with light. There is the whole continuum of the theories of kinematics of bodies which correctly explain the Michelson-Morley experiment and other experiments in which the velocity of light is measured. Based on the derived transformations, we derive the general formula for the velocity of light in vacuum measured in any inertial reference system. We explain why the Michelson-Morley and Kennedy-Thorndike experiments could not detect the ether. We present and discuss three examples of specific transformations. Finally, we explain the phenomenon of anisotropy of the cosmic microwave background radiation by means of the presented theory. The theory derived in this work is called the Special Theory of Ether – with any transverse contraction. The entire article contains only original research conducted by its authors. Keywords: Kinematics of bodies, Universal frame of reference, Transformation of time and position, One-way speed of light, Anisotropy of cosmic microwave background

  19. An Attitude Heading and Reference System For Marine Satellite Tracking Antenna

    DEFF Research Database (Denmark)

    Wang, Yunlong; Soltani, Mohsen; Hussain, Dil muhammed Akbar

    2017-01-01

    One of the most challenging problems for marine satellite tracking antennas (MSTAs) is to estimate the antenna attitude, which is affected by the ship motion, especially the ship vibration and rotational motions caused by ocean waves. To overcome this problem, an attitude heading and reference...... conditions, an attitude estimator based on virtual horizontal reference is introduced for situations of accelerometer malfunction, where the ship is suffering from wave shocks in high sea states. The performance of the designed AHRS for MSTA is assessed through hardware experiments using a Stewart platform...

  20. Nuclear Structure References (NSR) file

    International Nuclear Information System (INIS)

    Ewbank, W.B.

    1978-08-01

    The use of the Nuclear Structure References file by the Nuclear Data Project at ORNL is described. Much of the report concerns format information of interest only to those preparing input to the system or otherwise needing detailed knowledge of its internal structure. 17 figures

  1. Report from a quality assurance program on patients undergoing the MILD procedure.

    Science.gov (United States)

    Durkin, Brian; Romeiser, Jamie; Shroyer, A Laurie W; Schiller, Robin; Bae, Jin; Davis, Raphael P; Peyster, Robert; Benveniste, Helene

    2013-05-01

    To characterize trends in pain and functional outcomes and identify risk factors in patients with lumbar spinal stenosis (LSS) and neurogenic claudication undergoing the "Minimally Invasive Lumbar Decompression" (MILD) procedure. Retrospective observational cohort study. Academic multidisciplinary pain center at Stony Brook Medicine. Patients undergoing the MILD procedure from October 2010 to November 2012. De-identified perioperative, pain and function related data for 50 patients undergoing MILD were extracted from the Center for Pain Management's quality assessment database. Data included numerical rating scale (NRS), symptom severity and physical function (Zurich Claudication Questionnaire), functional status (Oswestry Disability Index [ODI]), pain interference scores (National Institutes of Health Patient-Reported Outcomes Measurement Information System [PROMIS]), and patients' self-reported low back and lower extremity pain distribution. No MILD patient incurred procedure-related complications. Average NRS scores decreased postoperatively and 64.3% of patients reported less pain at 3 months. Clinically meaningful functional ODI improvements of at least 20% from baseline were present in 25% of the patients at 6 months. Preliminary analysis of changes in PROMIS scores at 3 months revealed that pre-MILD "severe" lumbar canal stenosis may be associated with high risk of "no improvement." No such impact was observed for NRS or ODI outcomes. Overall, pain is reduced and functional status improved in LSS patients following the MILD procedure at 3 and 6 months. Given the small sample size, it is not yet possible to identify patient subgroups at risk for "no improvement." Continued follow-up of longer-term outcomes appears warranted to develop evidence-based patient selection criteria. Wiley Periodicals, Inc.

  2. Antibiotic prophylaxis for patients undergoing elective endoscopic ...

    African Journals Online (AJOL)

    Antibiotic prophylaxis for patients undergoing elective endoscopic retrograde cholangiopancreatography. M Brand, D Bisoz. Abstract. Background. Antibiotic prophylaxis for endoscopic retrograde cholangiopancreatography (ERCP) is controversial. We set out to assess the current antibiotic prescribing practice among ...

  3. The economic value of one ton CO2: what system of reference for public action?

    International Nuclear Information System (INIS)

    2007-04-01

    Given the convergence of scientific analyses of global warming and its consequences for the planet - evaluated for years by the Intergovernmental Panel on Climate Change (IPCC) - it is no longer possible to postpone the efforts required to reduce our emissions of greenhouse gases substantially. However, the choice of actions to take and the calendar of priorities are proving complex to define: the social and economic consequences are great, and neither France (which represents 2% of global emissions) nor Europe (15%) are up to treating the problem independently of the rest of the world. Faced with this challenge, and with budgetary constraints imposing a rationalisation of expenditure, public action must have measuring instruments at its disposal: the value of one ton of carbon is one such instrument. This Strategic Newswatch has a twofold objective: to recall the usefulness of this reference value which, though it cannot guarantee the validity of different public policies, may contribute to ensuring their consistency; and to present the different approaches and difficulties that producing such a reference system introduces. (author)

  4. [Evaluation of selected parameters of blood coagulation and fibrinolysis system in patients undergoing total hip replacement surgery with normovolemic hemodilution procedure and standard enoxaparine prophylaxis].

    Science.gov (United States)

    Piecuch, Wiesław; Sokołowska, Bozena; Dmoszyńska, Anna; Furmanik, Franciszek

    2003-01-01

    The aim of the study was to evaluate selected blood coagulation and fibrinolysis parameters in patients undergoing total hip replacement surgery with normovolemic hemodilution and standard enoksaparine profilaxis. The study included 66 patients undergoing hip replacement surgery. The group consisted of 51 women and 15 men, within the age range of 47-78, the mean age was 64. In 32 (subgroup II) patients the surgery was performed with the use of normovolemic hemodilution, in 34 (subgroup I) the hemodilution procedure was not applied. The enoksaparine as prophylaxis started 12 hours prior to surgery and continued during hospitalisation. The examination of the coagulation system was performed: on the day of the operation in the morning, on the day of the operation in the evening and on the first day after operation. We determined the concentrations of TAT and PAP complexes, prothrombin fragments 1 + 2 (F1 + 2) and d-dimers (DD). 1) during total hip replacement surgery and particularly in the period of the first 12 hours after the procedure marked activation of coagulation and fibrinolysis occurRed; 2) the application of the hemodilution procedure does not influence significantly the degree of coagulation and fibrinolysis disorders in the perioperative period, but could reduced incidence of thromboembolic complications in the postoperative period.

  5. Single and multispecies reference points for Baltic fish stocks

    DEFF Research Database (Denmark)

    Gislason, Henrik

    1999-01-01

    reference points. Management advice based on biomass reference points will also differ. In the single species situation the combinations of cod and pelagic fishing effort for which the equilibrium spawning- stock biomass of the three species is above the biomass reference points forms a rectangular area......Single and multispecies models are used to examine the effect of species interaction on biological reference points for cod, herring, and sprat in the Baltic. The results demonstrate that reference points are different in single and multispecies contexts. Reference points for fishing mortality...... based on single-species yield and SSB calculations are difficult to use when natural mortality depends on the absolute abundance of the predators and their alternative prey. Reference points based on maximizing total yield from the system may lead to impractical results when species interact...

  6. Guaiphenesin-ketamine-xylazine infusion to maintain anesthesia in mules undergoing field castration.

    Science.gov (United States)

    Vullo, Cecilia; Carluccio, Augusto; Robbe, Domenico; Meligrana, Marina; Petrucci, Linda; Catone, Giuseppe

    2017-10-11

    In order to determine whether a combination of guaiphenesin, ketamine and xylazine can induce safe and satisfactory anaesthesia in mules undergoing field castration, eight healthy adult intact male mules were employed. They were premedicated with intravenous (IV) xylazine (1.3 mg/kg); an additional dose of xylazine (0.3 mg/kg IV) was administered in case of inadequate depth of sedation. Anaesthesia was induced with IV thiopental (6 mg/kg). The quality of sedation and induction was recorded. Anaesthesia was maintained with an infusion of guaiphenesin (50 mg/mL), ketamine (2 mg/mL) and xylazine (1 mg/mL) (GKX). The spermatic cord of each testis was infiltrated with 5 mL of 2% lidocaine. During anaesthesia heart rate (HR), respiratory rate (RR), rectal temperature (RT) and haemoglobin oxygen saturation (SpO 2 ) were measured every 5 min. The data were analysed with simple one-way analysis of variance (ANOVA). A P value anesthesia, time of surgery and time of recovery were recorded. Only one mule required an additional dose of xylazine to achieve a satisfactory depth of sedation. Thiopental at the dose of 6 mg/kg IV resulted in smooth induction and lateral recumbency in all animals. GKX provided adequate anaesthesia to perform castration in all mules. Muscle relaxation was deemed adequate and physiological variables remained stable and within references values during the anaesthesia and did not change in response to surgical stimulation. Time (mean ± standard deviation) from the end of the infusion to sternal recumbency and time from sternal recumbency to standing were 27.7 ± 4.6 and 30.1 ± 7.7 min, respectively. The combination of xylazine, thiopental and GKX provides satisfactory short-term anaesthesia in mules undergoing field castration.

  7. Genetics Home Reference: systemic lupus erythematosus

    Science.gov (United States)

    ... Twitter Home Health Conditions Systemic lupus erythematosus Systemic lupus erythematosus Printable PDF Open All Close All Enable Javascript to view the expand/collapse boxes. Description Systemic lupus erythematosus (SLE) is a chronic disease that causes inflammation ...

  8. Performance of the Modified Mini-Mental State Examination (3MS) in Assessing Specific Cognitive Function in Patients Undergoing Peritoneal Dialysis

    Science.gov (United States)

    Li, Yi; Tian, Xue; Xiong, Zu-Ying; Liao, Jin-Lan; Hao, Li; Liu, Gui-Ling; Ren, Ye-Ping; Wang, Qin; Duan, Li-Ping; Zheng, Zhao-Xia; Quan, Wen-Xiang; Dong, Jie

    2016-01-01

    Purpose While Cognitive impairment (CI) has been identified as an independent risk factors for mortality in patients undergoing peritoneal dialysis (PD), it is inadequately assessed. We evaluated the applicability of the Modified Mini-Mental State Examination (3MS) in assessing specific cognitive function and compared it to a detailed neuropsychological test battery as the reference standard. Methods In this multicentric cross-sectional study, we enrolled 445 clinically stable patients from five PD units, who were undergoing PD for at least 3 months. The 3MS was evaluated for general cognitive function. A detailed neuropsychological battery including domains of immediate memory, delayed memory, executive function, language, and visuospatial ability were evaluated as reference standards. Sensitivity and specificity of the 3MS was determined by using receiver operating characteristic (ROC) analysis. Results The CI prevalence evaluated by 3MS was 23.6%. PD patients with CI performed worse in all cognitive domains. The 3MS correlated well with specific cognitive domains. However, 18.5%, 57.4%, 12.6%, 8.8%, and 41.2% of patients whom were idendified as normal by 3MS still showed executive dysfunction, immediate memory impairment, delayed memory impairment, and language-ability and visuospatial-ability impairment, respectively. The 3MS identified patients having specific cognitive dysfunction with varied extent of diagnostic value, with 0.50, 0.42, 0.35, 0.34, and 0.26 of Youden index in executive function, delayed memory, language ability, immediate memory, and visuospatial ability, respectively. Conclusions The 3MS is not a comprehensive instrument for major cognitive domains in PD patients. It could, however, be used for executive dysfunction and delayed memory impairment screening. PMID:27911914

  9. Assessment of a dynamic reference material for calibration of full-field measurement systems

    Science.gov (United States)

    Hack, Erwin; Feligiotti, Mara; Davighi, Andrea; Whelan, Maurice; Wang, Weizhuo V.; Patterson, Eann A.

    2012-10-01

    For holography and speckle interferometry the calibration of the sensitivity is a must, because illumination and observation directions vary across the field of view. A numerical estimate or a static calibration using rigid body motions is standard, and reference materials exist for static strain calibration. Recently, reference materials for the dynamic calibration of optical instruments of displacement and strain measurement were designed and prototypes were manufactured in the European FP7 project ADVISE. We review the properties of the reference material and the concept of traceability for the field of displacement values by using a calibrated single point transducer. The mode shape is assessed using out-of-plane DSPI, Finite Element Analysis as well as analytic solutions of the plate vibration. We present measurements using stroboscopic DSPI on the reference material under acoustic excitation and compare the measured mode shapes to the ones predicted by FE analysis. We apply different comparison methodologies based on point-by-point deviations and on decomposition of the mode shapes into a set of orthogonal basis functions. The latter method is well suited to assess stability and reproducibility of a mode shape. Finally, the deviations are used to estimate the reference material uncertainty which is an essential parameter for determining the calibration uncertainty. Uncertainty contributions of the DSPI set-up are taken into account. To conclude, the application area and limitations of the reference material are discussed.

  10. Anthology of the renin-angiotensin system: a one hundred reference approach to angiotensin II antagonists.

    Science.gov (United States)

    Ménard, J

    1993-04-01

    To provide a historical overview of the renin-angiotensin system as a guide to the introduction of a new therapeutic pathway, non-peptide inhibition of a angiotensin II. One hundred references were selected as a personal preference, for their originality or for their potential impact on medicine. This review raises the following questions for future research. (1) Will the long-term cardiovascular effects of angiotensin converting enzyme (ACE) inhibition, angiotensin II antagonism and renin inhibition be similar or not, and dependent or independent of blood pressure levels? (2) What are the local-regional interactions between vasoconstrictor and vasodilator systems, and does the renin-angiotensin system synchronize these regional hemodynamic regulatory mechanisms? (3) If hypertension is the result of an interaction between genetic and environmental factors, do proteins secreted through constitutive pathways contribute to the genetic abnormality (prorenin, angiotensinogen, ACE) while regulated secretion (renin) and other regulatory mechanisms (angiotensin II receptors) provide biological support for the environmental effects?

  11. Growth references

    NARCIS (Netherlands)

    Buuren, S. van

    2007-01-01

    A growth reference describes the variation of an anthropometric measurement within a group of individuals. A reference is a tool for grouping and analyzing data and provides a common basis for comparing populations.1 A well known type of reference is the age-conditional growth diagram. The

  12. Online Reference Service--How to Begin: A Selected Bibliography.

    Science.gov (United States)

    Shroder, Emelie J., Ed.

    1982-01-01

    Materials in this bibliography were selected and recommended by members of the Use of Machine-Assisted Reference in Public Libraries Committee, Reference and Adult Services Division, American Library Association. Topics include: financial aspects, equipment and communications considerations, comparing databases and database systems, advertising…

  13. Establishing a Business Process Reference Model for Universities

    KAUST Repository

    Svensson, Carsten

    2012-09-01

    Modern universities are by any standard complex organizations that, from an IT perspective, present a number of unique challenges. This paper will propose establishing a business process reference framework. The benefit to the users would be a better understanding of the system landscape, business process enablement, collection of performance data and systematic reuse of existing community experience and knowledge. For these reasons reference models such as the SCOR (Supply Chain Operations Reference), DCOR (Design Chain Operations Reference) and ITIL (Information Technology Infrastructure Library) have gained popularity among organizations in both the private and public sectors. We speculate that this success can be replicated in a university setting. Furthermore the paper will outline how the research group suggests moving ahead with the research which will lead to a reference model.

  14. Computerized literature reference system: use of an optical scanner and optical character recognition software.

    Science.gov (United States)

    Lossef, S V; Schwartz, L H

    1990-09-01

    A computerized reference system for radiology journal articles was developed by using an IBM-compatible personal computer with a hand-held optical scanner and optical character recognition software. This allows direct entry of scanned text from printed material into word processing or data-base files. Additionally, line diagrams and photographs of radiographs can be incorporated into these files. A text search and retrieval software program enables rapid searching for keywords in scanned documents. The hand scanner and software programs are commercially available, relatively inexpensive, and easily used. This permits construction of a personalized radiology literature file of readily accessible text and images requiring minimal typing or keystroke entry.

  15. Prescribing during pregnancy and lactation with reference to the Swedish classification system - A population-based study among Danish women

    NARCIS (Netherlands)

    Olesen, C; Sorensen, HT; de Jong-van den Berg, L; Olsen, J; Steffensen, FH

    Aim. To assess the current prescribing pattern for 15,756 primiparae before, during, and after their pregnancies with reference to fetal and neonatal risk. Method. A prescription database study with linkage to The Danish Medical Birth Registry from 1991 to 1996. The drug subsidy system in Danish

  16. Reference-shaping adaptive control by using gradient descent optimizers.

    Directory of Open Access Journals (Sweden)

    Baris Baykant Alagoz

    Full Text Available This study presents a model reference adaptive control scheme based on reference-shaping approach. The proposed adaptive control structure includes two optimizer processes that perform gradient descent optimization. The first process is the control optimizer that generates appropriate control signal for tracking of the controlled system output to a reference model output. The second process is the adaptation optimizer that performs for estimation of a time-varying adaptation gain, and it contributes to improvement of control signal generation. Numerical update equations derived for adaptation gain and control signal perform gradient descent optimization in order to decrease the model mismatch errors. To reduce noise sensitivity of the system, a dead zone rule is applied to the adaptation process. Simulation examples show the performance of the proposed Reference-Shaping Adaptive Control (RSAC method for several test scenarios. An experimental study demonstrates application of method for rotor control.

  17. Connecting VLBI and Gaia celestial reference frames

    Directory of Open Access Journals (Sweden)

    Zinovy Malkin

    2016-09-01

    Full Text Available The current state of the link problem between radio and optical celestial reference frames is considered.The main objectives of the investigations in this direction during the next few years are the preparation of a comparisonand the mutual orientation and rotation between the optical it Gaia Celestial Reference Frame (GCRFand the 3rd generation radio International Celestial Reference Frame (ICRF3, obtained from VLBI observations.Both systems, ideally, should be a realization of the ICRS (International Celestial Reference System at micro-arcsecond level accuracy.Therefore, the link accuracy between the ICRF and GCRF should be obtained with similar error level, which is not a trivial taskdue to relatively large systematic and random errors in source positions at different frequency bands.In this paper, a brief overview of recent work on the GCRF--ICRF link is presented.Additional possibilities to improve the GCRF--ICRF link accuracy are discussed.The suggestion is made to use astrometric radio sources with optical magnitude to 20$^m$ rather than to 18$^m$ as currently plannedfor the GCRF--ICRF link.In addition, the use of radio stars is also a prospective method to obtain independent and accurate orientation between the Gaia frame and the ICRF.

  18. Connecting VLBI and Gaia Celestial Reference Frames

    Energy Technology Data Exchange (ETDEWEB)

    Malkin, Zinovy, E-mail: malkin@gao.spb.ru [Department of Radio Astronomy Research, The Pulkovo Astronomical Observatory, St. Petersburg (Russian Federation); Institute of Earth Sciences, St. Petersburg State University, St. Petersburg (Russian Federation); Astronomy and Cosmic Geodesy Department, Kazan Federal University, Kazan (Russian Federation)

    2016-09-12

    The current state of the link problem between radio and optical celestial reference frames is considered. The main objectives of the investigations in this direction during the next few years are the preparation of a comparison and the mutual orientation and rotation between the optical Gaia Celestial Reference Frame (GCRF) and the 3rd generation radio International Celestial Reference Frame (ICRF3), obtained from VLBI observations. Both systems, ideally, should be a realization of the ICRS (International Celestial Reference System) at micro-arcsecond level accuracy. Therefore, the link accuracy between the ICRF and GCRF should be obtained with similar error level, which is not a trivial task due to relatively large systematic and random errors in source positions at different frequency bands. In this paper, a brief overview of recent work on the GCRF–ICRF link is presented. Additional possibilities to improve the GCRF–ICRF link accuracy are discussed. The suggestion is made to use astrometric radio sources with optical magnitude to 20{sup m} rather than to 18{sup m} as currently planned for the GCRF–ICRF link. In addition, the use of radio stars is also a prospective method to obtain independent and accurate orientation between the Gaia frame and the ICRF.

  19. Reference pricing system and competition: case study from Portugal.

    Science.gov (United States)

    Portela, Conceiçăo

    2009-10-01

    To characterize the patterns of competition for a sample of drugs in the Portuguese pharmaceutical market before (January 2002-March 2003) and after (April 2003-June 2003) the introduction of the reference pricing system (RPS). We performed a descriptive, retrospective, longitudinal analysis, with monthly observations from January 2002 until June 2003 of 15 homogeneous groups. The groups represented the upper limit of public pharmaceutical expenditure in the RPS segment in 2003 (n=270). Measures of competition were: 1) number of presentations; 2) prescriptions' concentration in the generic and originator (brand) segments, using Herfindahl-Hirschman Index (HHI); and 3) dominant positions of market leader in the homogeneous group. A correlation analysis between the number of presentations, the HHI, and the dominant position of the market leader was performed using Pearson coefficient of correlation. The structure of the market changed with the introduction of RPS. We found an increasing number of generic presentations (from 4+/-3 to 7+/-4; mean+/-standard deviation) and a decrease in the HHI for the generics market segment (from 0.7+/-0.2 to 0.6+/-0.3). There was a negative correlation between those variables that increased after the introduction of RPS (from -0.6 to -0.8). The HHI for brands and the dominant positions remained unchanged. After the implementation of RPS, the increased competition was mainly driven by economic and social agents in the generics market segment but not in the brands market segment.

  20. A Modernized National Spatial Reference System in 2022: Focus on the Caribbean Terrestrial Reference Frame

    Science.gov (United States)

    Roman, D. R.

    2017-12-01

    In 2022, the National Geodetic Survey will replace all three NAD 83 reference frames the four new terrestrial reference frames. Each frame will be named after a tectonic plate (North American, Pacific, Caribbean and Mariana) and each will be related to the IGS frame through three Euler Pole parameters (EPPs). This talk will focus on practical application in the Caribbean region. A working group is being re-established for development of the North American region and will likely also result in analysis of the Pacific region as well. Both of these regions are adequately covered with existing CORS sites to model the EPPs. The Mariana region currently lacks sufficient coverage, but a separate project is underway to collect additional information to help in defining EPPs for that region at a later date. The Caribbean region has existing robust coverage through UNAVCO's COCONet and other data sets, but these require further analysis. This discussion will focus on practical examination of Caribbean sites to establish candidates for determining the Caribbean frame EPPs as well as an examination of any remaining velocities that might inform a model of the remaining velocities within that frame (Intra-Frame Velocity Model). NGS has a vested interest in defining such a model to meet obligations to U.S. citizens in Puerto Rico and the U.S. Virgin Islands. Beyond this, NGS aims to collaborate with other countries in the region through efforts with SIRGAS and UN-GGIM-Americas for a more acceptable regional model to serve everyone's needs.

  1. Systemic Assessment of Patients Undergoing Dental Implant ...

    African Journals Online (AJOL)

    Background: Procedure‑related and patient‑related factors influence the prognosis of dental implants to a major extent. Hence, we aimed to evaluate and analyze various systemic factors in patients receiving dental implants. Materials and Methods: Fifty‑one patients were included in the study, in which a total of 110 dental ...

  2. EARS: Electronic Access to Reference Service.

    Science.gov (United States)

    Weise, F O; Borgendale, M

    1986-10-01

    Electronic Access to Reference Service (EARS) is a front end to the Health Sciences Library's electronic mail system, with links to the online public catalog. EARS, which became operational in September 1984, is accessed by users at remote sites with either a terminal or microcomputer. It is menu-driven, allowing users to request: a computerized literature search, reference information, a photocopy of a journal article, or a book. This paper traces the history of EARS and discusses its use, its impact on library staff and services, and factors that influence the diffusion of new technology.

  3. Reference materials and representative test materials: the nanotechnology case

    International Nuclear Information System (INIS)

    Roebben, G.; Rasmussen, K.; Kestens, V.; Linsinger, T. P. J.; Rauscher, H.; Emons, H.; Stamm, H.

    2013-01-01

    An increasing number of chemical, physical and biological tests are performed on manufactured nanomaterials for scientific and regulatory purposes. Existing test guidelines and measurement methods are not always directly applicable to or relevant for nanomaterials. Therefore, it is necessary to verify the use of the existing methods with nanomaterials, thereby identifying where modifications are needed, and where new methods need to be developed and validated. Efforts for verification, development and validation of methods as well as quality assurance of (routine) test results significantly benefit from the availability of suitable test and reference materials. This paper provides an overview of the existing types of reference materials and introduces a new class of test materials for which the term ‘representative test material’ is proposed. The three generic concepts of certified reference material, reference material(non-certified) and representative test material constitute a comprehensive system of benchmarks that can be used by all measurement and testing communities, regardless of their specific discipline. This paper illustrates this system with examples from the field of nanomaterials, including reference materials and representative test materials developed at the European Commission’s Joint Research Centre, in particular at the Institute for Reference Materials and Measurements (IRMM), and at the Institute for Health and Consumer Protection (IHCP).

  4. General Anaesthesia Protocols for Patients Undergoing Electroconvulsive Therapy

    Science.gov (United States)

    Narayanan, Aravind; Lal, Chandar; Al-Sinawi, Hamed

    2017-01-01

    Objectives This study aimed to review general anaesthesia protocols for patients undergoing electroconvulsive therapy (ECT) at a tertiary care hospital in Oman, particularly with regards to clinical profile, potential drug interactions and patient outcomes. Methods This retrospective study took place at the Sultan Qaboos University Hospital (SQUH), Muscat, Oman. The electronic medical records of patients undergoing ECT at SQUH between January 2010 and December 2014 were reviewed for demographic characteristics and therapy details. Results A total of 504 modified ECT sessions were performed on 57 patients during the study period. All of the patients underwent a uniform general anaesthetic regimen consisting of propofol and succinylcholine; however, they received different doses between sessions, as determined by the treating anaesthesiologist. Variations in drug doses between sessions in the same patient could not be attributed to any particular factor. Self-limiting tachycardia and hypertension were periprocedural complications noted among all patients. One patient developed aspiration pneumonitis (1.8%). Conclusion All patients undergoing ECT received a general anaesthetic regimen including propofol and succinylcholine. However, the interplay of anaesthetic drugs with ECT efficacy could not be established due to a lack of comprehensive data, particularly with respect to seizure duration. In addition, the impact of concurrent antipsychotic therapy on anaesthetic dose and subsequent complications could not be determined. PMID:28417028

  5. Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE), Version 5.0: Integrated Reliability and Risk Analysis System (IRRAS) reference manual. Volume 2

    International Nuclear Information System (INIS)

    Russell, K.D.; Kvarfordt, K.J.; Skinner, N.L.; Wood, S.T.; Rasmuson, D.M.

    1994-07-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) refers to a set of several microcomputer programs that were developed to create and analyze probabilistic risk assessments (PRAs), primarily for nuclear power plants. The Integrated Reliability and Risk Analysis System (IRRAS) is a state-of-the-art, microcomputer-based probabilistic risk assessment (PRA) model development and analysis tool to address key nuclear plant safety issues. IRRAS is an integrated software tool that gives the use the ability to create and analyze fault trees and accident sequences using a microcomputer. This program provides functions that range from graphical fault tree construction to cut set generation and quantification to report generation. Version 1.0 of the IRRAS program was released in February of 1987. Since then, many user comments and enhancements have been incorporated into the program providing a much more powerful and user-friendly system. This version has been designated IRRAS 5.0 and is the subject of this Reference Manual. Version 5.0 of IRRAS provides the same capabilities as earlier versions and ads the ability to perform location transformations, seismic analysis, and provides enhancements to the user interface as well as improved algorithm performance. Additionally, version 5.0 contains new alphanumeric fault tree and event used for event tree rules, recovery rules, and end state partitioning

  6. Determinants of anxiety in patients with advanced somatic disease: differences and similarities between patients undergoing renal replacement therapies and patients suffering from cancer.

    Science.gov (United States)

    Janiszewska, Justyna; Lichodziejewska-Niemierko, Monika; Gołębiewska, Justyna; Majkowicz, Mikołaj; Rutkowski, Bolesław

    2013-10-01

    Anxiety is the most frequent emotional reaction to the chronic somatic disease. However, little is known about anxiety and coping strategies in patients with end-stage renal disease (ESRD) undergoing renal replacement therapies (RRTs). The purpose of the study was to assess the intensity and determinants of anxiety in patients treated with different RRTs in comparison with end-stage breast cancer patients and healthy controls. The study involved (1) ESRD patients undergoing different RRTs: 32 renal transplant recipients, 31 maintenance haemodialysis and 21 chronic peritoneal dialysis patients, (2) women with end-stage breast cancer (n = 25) and (3) healthy persons (n = 55). We used State-Trait Anxiety Inventory, Scale of Personal Religiousness, Mental Adjustment to Cancer Scale, Rotterdam Symptom Checklist with reference to medical history. The data thus obtained were analysed using the analysis of variance, the Tukey's HSD post hoc test and Spearman's rank correlation coefficient. Both ESRD and breast cancer patients revealed higher level of anxiety state and trait than healthy controls; however, there was no statistically significant difference found between both findings. There was a tendency towards higher levels of anxiety state in breast cancer patients when compared to ESRD patients undergoing the RRT treatment and for both groups non-constructive coping strategies correlated with the levels of anxiety state. With ESRD patients undergoing RRTs, the intensity of anxiety state did not depend on the mode of treatment but on the correlation between the levels of anxiety and the general quality of their life, psychological condition and social activity. In patients with advanced somatic disease (ESRD and end-stage breast cancer), non-constructive strategies of coping with the disease require further evaluation and possibly psychological support.

  7. Performance evaluation of the reference system for calibration of IPEN activities

    Energy Technology Data Exchange (ETDEWEB)

    Martins, Elaine Wirney; Potiens, Maria da Penha A., E-mail: ewmartins@ipen.br, E-mail: mppalbu@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    The formation of good quality image in nuclear medicine services depends on several factors, including the radiopharmaceutical activity, which must be well determined by a specific apparatus, in perfect operating condition, called activimeter. Therefore, the establishment of a quality control program for measuring the radiopharmaceuticals radioactivity before being administered to the patient is crucial to the safe and effective use of the radiopharmaceuticals used in diagnostic and therapeutical procedures. Two activimeters, belonging by the Laboratorio de Calibracao do Instrumentos (LCI) of Instituto de Pesquisas Energeticas e Nucleares (IPEN), were evaluated: the secondary standard system NPL-CRC radionuclide calibrator, manufactured by Southern Scientific, and the work standard system CRC-15BT with traceability to National Institute of Standard and Technology (NIST). A set of standard sources of the radionuclides {sup 1}'3{sup 3}Ba, {sup 57}Co and {sup 137}Cs was used as reference to perform the quality control tests. The precision, accuracy and repeatability tests were in agreement with those established by the CNEN-NE 3.05 Brazilian standard, which recommends the variation limit of up to 10%, 5% and 5% respectively. The results obtained for the reproducibility tests presented a variation always below 1,5%, which means it is within the IEC 61674 international standard recommendation of up to 3%. Activimeters response regarding linearity showed concordance between the measured activities and the theoretical curve for both activimeters. (author)

  8. Recent references

    International Nuclear Information System (INIS)

    Ramavataram, S.

    1991-01-01

    In support of a continuing program of systematic evaluation of nuclear structure data, the National Nuclear Data Center maintains a complete computer file of references to the nuclear physics literature. Each reference is tagged by a keyword string, which indicates the kinds of data contained in the article. This master file of Nuclear Structure References (NSR) contains complete keyword indexes to literature published since 1969, with partial indexing of older references. Any reader who finds errors in the keyword descriptions is urged to report them to the National Nuclear Data Center so that the master NSR file can be corrected. In 1966, the first collection of Recent References was published as a separate issue of Nuclear Data Sheets. Every four months since 1970, a similar indexed bibliography to new nuclear experiments has been prepared from additions to the NSR file and published. Beginning in 1978, Recent References was cumulated annually, with the third issue completely superseding the two issues previously published during a given year. Due to publication policy changes, cumulation of Recent Reference was discontinued in 1986. The volume and issue number of all the cumulative issues published to date are given. NNDC will continue to respond to individual requests for special bibliographies on nuclear physics topics, in addition to those easily obtained from Recent References. If the required information is available from the keyword string, a reference list can be prepared automatically from the computer files. This service can be provided on request, in exchange for the timely communication of new nuclear physics results (e.g., preprints). A current copy of the NSR file may also be obtained in a standard format on magnetic tape from NNDC. Requests for special searches of the NSR file may also be directed to the National Nuclear Data Center

  9. The role of certified reference materials in material control and accounting

    International Nuclear Information System (INIS)

    Turel, S.P.

    1979-01-01

    One way of providing an adequate material control and accounting system for the nuclear fuel cycle is to calculate material unaccounted for (MUF) after a physical inventory and to compare the limit of error of the MUF value (LEMUF) against prescribed criteria. To achieve a meaningful LEMUF, a programme for the continuing determination of systematic and random errors is necessary. Within this programme it is necessary to achieve traceability of all Special Nuclear Material (SNM) control and accounting measurements to an International/National Measurement System by means of Certified Reference Materials. SNM measurements for control and accounting are made internationally on a great variety of materials using many diverse measurement procedures by a large number of facilities. To achieve valid overall accountability over this great variety of measurements there must be some means of relating all these measurements and their uncertainties to each other. This is best achieved by an International/National Measurement System (IMS/NMS). To this end, all individual measurement systems must be compatible to the IMS/NMS and all measurement results must be traceable to appropriate international/national Primary Certified Reference Materials. To obtain this necessary compatibility for any given SNM measurement system, secondary certified reference materials or working reference materials are needed for every class of SNM and each type of measurement system. Ways to achieve ''traceability'' and the various types of certified reference material are defined and discussed in this paper. (author)

  10. 300 Area waste acid treatment system closure plan

    International Nuclear Information System (INIS)

    LUKE, S.N.

    1999-01-01

    The Hanford Facility Dangerous Waste Permit Application is considered to be a single application organized into a General Information Portion (document number DOERL-91-28) and a Unit-Specific Portion. The scope of the Unit-Specific Portion includes closure plan documentation submitted for individual, treatment, storage, and/or disposal units undergoing closure, such as the 300 Area Waste Acid Treatment System. Documentation contained in the General Information Portion is broader in nature and could be used by multiple treatment, storage, and/or disposal units (e.g., the glossary provided in the General Information Portion). Whenever appropriate, 300 Area Waste Acid Treatment System documentation makes cross-reference to the General Information Portion, rather than duplicating text. This 300 Area Waste Acid Treatment System Closure Plan (Revision 2) includes a Hanford Facility Dangerous Waste Permit Application, Part A, Form 3. Information provided in this closure plan is current as of April 1999

  11. 300 Area waste acid treatment system closure plan

    Energy Technology Data Exchange (ETDEWEB)

    LUKE, S.N.

    1999-05-17

    The Hanford Facility Dangerous Waste Permit Application is considered to be a single application organized into a General Information Portion (document number DOERL-91-28) and a Unit-Specific Portion. The scope of the Unit-Specific Portion includes closure plan documentation submitted for individual, treatment, storage, and/or disposal units undergoing closure, such as the 300 Area Waste Acid Treatment System. Documentation contained in the General Information Portion is broader in nature and could be used by multiple treatment, storage, and/or disposal units (e.g., the glossary provided in the General Information Portion). Whenever appropriate, 300 Area Waste Acid Treatment System documentation makes cross-reference to the General Information Portion, rather than duplicating text. This 300 Area Waste Acid Treatment System Closure Plan (Revision 2) includes a Hanford Facility Dangerous Waste Permit Application, Part A, Form 3. Information provided in this closure plan is current as of April 1999.

  12. Cardiovascular impact in patients undergoing maintenance hemodialysis: Clinical management considerations.

    Science.gov (United States)

    Chirakarnjanakorn, Srisakul; Navaneethan, Sankar D; Francis, Gary S; Tang, W H Wilson

    2017-04-01

    Patients undergoing maintenance hemodialysis develop both structural and functional cardiovascular abnormalities. Despite improvement of dialysis technology, cardiovascular mortality of this population remains high. The pathophysiological mechanisms of these changes are complex and not well understood. It has been postulated that several non-traditional, uremic-related risk factors, especially the long-term uremic state, which may affect the cardiovascular system. There are many cardiovascular changes that occur in chronic kidney disease including left ventricular hypertrophy, myocardial fibrosis, microvascular disease, accelerated atherosclerosis and arteriosclerosis. These structural and functional changes in patients receiving chronic dialysis make them more susceptible to myocardial ischemia. Hemodialysis itself may adversely affect the cardiovascular system due to non-physiologic fluid removal, leading to hemodynamic instability and initiation of systemic inflammation. In the past decade there has been growing awareness that pathophysiological mechanisms cause cardiovascular dysfunction in patients on chronic dialysis, and there are now pharmacological and non-pharmacological therapies that may improve the poor quality of life and high mortality rate that these patients experience. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Virtual reconstruction of modern and fossil hominoid crania: consequences of reference sample choice.

    Science.gov (United States)

    Senck, Sascha; Bookstein, Fred L; Benazzi, Stefano; Kastner, Johann; Weber, Gerhard W

    2015-05-01

    Most hominin cranial fossils are incomplete and require reconstruction prior to subsequent analyses. Missing data can be estimated by geometric morphometrics using information from complete specimens, for example, by using thin-plate splines. In this study, we estimate missing data in several virtually fragmented models of hominoid crania (Homo, Pan, Pongo) and fossil hominins (e.g., Australopithecus africanus, Homo heidelbergensis). The aim is to investigate in which way different references influence estimations of cranial shape and how this information can be employed in the reconstruction of fossils. We used a sample of 64 three-dimensional digital models of complete human, chimpanzee, and orangutan crania and a set of 758 landmarks and semilandmarks. The virtually knocked out neurocranial and facial areas that were reconstructed corresponded to those of a real case found in A.L. 444-2 (A. afarensis) cranium. Accuracy of multiple intraspecies and interspecies reconstructions was computed as the maximum square root of the mean squared difference between the original and the reconstruction (root mean square). The results show that the uncertainty in reconstructions is a function of both the geometry of the knockout area and the dissimilarity between the reference sample and the specimen(s) undergoing reconstruction. We suggest that it is possible to estimate large missing cranial areas if the shape of the reference is similar enough to the shape of the specimen reconstructed, though caution must be exercised when employing these reconstructions in subsequent analyses. We provide a potential guide for the choice of the reference by means of bending energy. © 2015 Wiley Periodicals, Inc.

  14. Model Predictive Control for Offset-Free Reference Tracking

    Czech Academy of Sciences Publication Activity Database

    Belda, Květoslav

    2016-01-01

    Roč. 5, č. 1 (2016), s. 8-13 ISSN 1805-3386 Institutional support: RVO:67985556 Keywords : offset-free reference tracking * predictive control * ARX model * state-space model * multi-input multi-output system * robotic system * mechatronic system Subject RIV: BC - Control Systems Theory http://library.utia.cas.cz/separaty/2016/AS/belda-0458355.pdf

  15. A survey of reference electrodes for high temperature waters

    International Nuclear Information System (INIS)

    Molander, A.; Eriksson, Sture; Pein, K.

    2000-11-01

    In nuclear power plants, corrosion potential measurements are used to follow the conditions for different corrosion types in reactor systems, particularly IGSCC in BWRs. The goal of this work has been to give a survey of reference electrodes for high temperature water, both those that are used for nuclear environments and those that are judged to possible future development. The reference electrodes that are used today in nuclear power plants for corrosion potential measurements are of three types. Silver chloride electrodes, membrane electrodes and platinum electrodes (hydrogen electrodes). The principals for their function is described as well as the conversion of measured potentials to the SHE scale (Standard Hydrogen Electrode). Silver chloride electrodes consist of an inner reference system of silver chloride in equilibrium with a chloride solution. The silver chloride electrode is the most common reference electrode and can be used in several different systems. Platinum electrodes are usually more robust and are particularly suitable to use in BWR environment to follow the hydrogen dosage, but have limitations at low and no hydrogen dosage. Ceramic membrane electrodes can be with different types of internal reference system. They were originally developed for pH measurements in high temperature water. If pH is constant, the membrane electrode can be used as reference electrode. A survey of ceramic reference electrodes for high temperature water is given. A ceramic membrane of the type used works as an oxygen conductor, so the potential and pH in surrounding medium is in equilibrium with the internal reference system. A survey of the lately development of electrodes is presented in order to explain why the different types of electrodes are developed as well as to give a background to the possibilities and limitations with the different electrodes. Possibilities of future development of electrodes are also given. For measurements at low or no hydrogen dosage

  16. Development of beta reference radiations

    International Nuclear Information System (INIS)

    Wan Zhaoyong; Cai Shanyu; Li Yanbo; Yin Wei; Feng Jiamin; Sun Yuhua; Li Yongqiang

    1997-09-01

    A system of beta reference radiation has been developed, that is composed of 740 MBq 147 Pm beta source, 74 MBq and 740 MBq 90 Sr + 90 Y β sources, compensation filters, a source handling tool, a source jig, spacing bars, a shutter, a control unit and a beta dose meter calibration stand. For 740 MBq 147 Pm and 74 MBq 90 Sr + 90 Y beta reference radiations with compensation filters and 740 MBq 90 Sr + 90 Y beta reference radiation without compensation filter, at 20 cm, 30 cm and 30 cm distance separately; the residual energy of maximum is 0.14 MeV, 1.98 MeV and 2.18 MeV separately; the absorbed dose to tissue D (0.07) is 1.547 mGy/h (1996-05-20), 5.037 mGy/h (1996-05-10) and 93.57 mGy/h (1996-05-15) separately; the total uncertainty is 3.0%, 1.7% and 1.7% separately. For the first and the second beta reference radiation, the dose rate variability in the area of 18 cm diameter in the plane perpendicular to the beta-ray beam axis is within +-6% and +-3% separately. (3 refs., 2 tabs., 8 figs.)

  17. The variability of inner ear orientation in saurischian dinosaurs: testing the use of semicircular canals as a reference system for comparative anatomy

    Directory of Open Access Journals (Sweden)

    Jesús Marugán-Lobón

    2013-08-01

    Full Text Available The vestibular system of the inner ear houses three semicircular canals—oriented on three nearly-orthogonal planes—that respond to angular acceleration stimuli. In recent years, the orientation of the lateral semicircular canal (LSC has been regularly used to determine skull orientations for comparative purposes in studies of non-avian dinosaurs. Such orientations have been inferred based on fixing the LSC to a common set of coordinates (parallel to the Earth’s horizon, given that the orientation to gravity of this sensory system is assumed constant among taxa. Under this assumption, the LSC is used as a baseline (a reference system both to estimate how the animals held their heads and to describe craniofacial variation among dinosaurs. However, the available data in living birds (extant saurischian dinosaurs suggests that the orientation of the LSC in non-avian saurischian dinosaurs could have been very variable and taxon-specific. If such were the case, using the LSC as a comparative reference system would cause inappropriate visual perceptions of craniofacial organization, leading to significant descriptive inconsistencies among taxa. Here, we used Procrustes methods (Geometric Morphometrics, a suite of analytical tools that compares morphology on the basis of shared landmark homology, to show that the variability of LSC relative to skull landmarks is large (ca. 50° and likely unpredictable, thus making it an inconsistent reference system for comparing and describing the skulls of saurischian (sauropodomorph and theropod dinosaurs. In light of our results, the lateral semicircular canal is an inconsistent baseline for comparative studies of craniofacial morphology in dinosaurs.

  18. Burden of Geriatric Events Among Older Adults Undergoing Major Cancer Surgery.

    Science.gov (United States)

    Tan, Hung-Jui; Saliba, Debra; Kwan, Lorna; Moore, Alison A; Litwin, Mark S

    2016-04-10

    Most malignancies are diagnosed in older adults who are potentially susceptible to aging-related health conditions; however, the manifestation of geriatric syndromes during surgical cancer treatment is not well quantified. Accordingly, we sought to assess the prevalence and ramifications of geriatric events during major surgery for cancer. Using Nationwide Inpatient Sample data from 2009 to 2011, we examined hospital admissions for major cancer surgery among elderly patients (ie, age ≥ 65 years) and a referent group age 55 to 64 years. From these observations, we identified geriatric events that included delirium, dehydration, falls and fractures, failure to thrive, and pressure ulcers. We then estimated the collective prevalence of these events according to age, comorbidity, and cancer site and further explored their relationship with other hospital-based outcomes. Within a weighted sample of 939,150 patients, we identified at least one event in 9.2% of patients. Geriatric events were most common among patients age ≥ 75 years, with a Charlson comorbidity score ≥ 2, and who were undergoing surgery for cancer of the bladder, ovary, colon and/or rectum, pancreas, or stomach (P geriatric event had a greater likelihood of concurrent complications (odds ratio [OR], 3.73; 95% CI, 3.55 to 3.92), prolonged hospitalization (OR, 5.47; 95% CI, 5.16 to 5.80), incurring high cost (OR, 4.97; 95% CI, 4.58 to 5.39), inpatient mortality (OR, 3.22; 95% CI, 2.94 to 3.53), and a discharge disposition other than home (OR, 3.64; 95% CI, 3.46 to 3.84). Many older patients who receive cancer-directed surgery experience a geriatric event, particularly those who undergo major abdominal surgery. These events are linked to operative morbidity, prolonged hospitalization, and more expensive health care. As our population ages, efforts focused on addressing conditions and complications that are more common in older adults will be essential to delivering high-quality cancer care. © 2016 by

  19. Hypovitaminosis D in patients undergoing kidney transplant: the importance of sunlight exposure

    Directory of Open Access Journals (Sweden)

    Cristiane F. Vilarta

    Full Text Available OBJECTIVES: Recent studies have shown a high prevalence of hypovitaminosis D, defined as a serum 25-hydroxyvitamin D level less than 30 ng/ml, in both healthy populations and patients with chronic kidney disease. Patients undergoing kidney transplant are at an increased risk of skin cancer and are advised to avoid sunlight exposure. Therefore, these patients might share two major risk factors for hypovitaminosis D: chronic kidney disease and low sunlight exposure. This paper describes the prevalence and clinical characteristics of hypovitaminosis D among patients undergoing kidney transplant. METHODS: We evaluated 25-hydroxyvitamin D serum levels in a representative sample of patients undergoing kidney transplant. We sought to determine the prevalence of hypovitaminosis D, compare these patients with a control group, and identify factors associated with hypovitaminosis D (e.g., sunlight exposure and dietary habits. RESULTS: Hypovitaminosis D was found in 79% of patients undergoing kidney transplant, and the major associated factor was low sunlight exposure. These patients had higher creatinine and intact parathyroid hormone serum levels, with 25-hydroxyvitamin D being inversely correlated with intact parathyroid hormone serum levels. Compared with the control group, patients undergoing kidney transplant presented a higher prevalence of 25-hydroxyvitamin D deficiency and lower serum calcium, phosphate and albumin but higher creatinine and intact parathyroid hormone levels. CONCLUSIONS: Our results confirmed the high prevalence of hypovitaminosis D in patients undergoing kidney transplant. Therapeutic strategies such as moderate sunlight exposure and vitamin D supplementation should be seriously considered for this population.

  20. Coagulation management in patients undergoing neurosurgical procedures.

    Science.gov (United States)

    Robba, Chiara; Bertuetti, Rita; Rasulo, Frank; Bertuccio, Alessando; Matta, Basil

    2017-10-01

    Management of coagulation in neurosurgical procedures is challenging. In this contest, it is imperative to avoid further intracranial bleeding. Perioperative bleeding can be associated with a number of factors, including anticoagulant drugs and coagulation status but is also linked to the characteristic and the site of the intracranial disorder. The aim of this review will be to focus primarily on the new evidence regarding the management of coagulation in patients undergoing craniotomy for neurosurgical procedures. Antihemostatic and anticoagulant drugs have shown to be associated with perioperative bleeding. On the other hand, an increased risk of venous thromboembolism and hypercoagulative state after elective and emergency neurosurgery, in particular after brain tumor surgery, has been described in several patients. To balance the risk between thrombosis and bleeding, it is important to be familiar with the perioperative changes in coagulation and with the recent management guidelines for anticoagulated patients undergoing neurosurgical procedures, in particular for those taking new direct anticoagulants. We have considered the current clinical trials and literature regarding both safety and efficacy of deep venous thrombosis prophylaxis in the neurosurgical population. These were mainly trials concerning both elective surgical and intensive care patients with a poor grade intracranial bleed or multiple traumas with an associated severe traumatic brain injury (TBI). Coagulation management remains a major issue in patients undergoing neurosurgical procedures. However, in this field of research, literature quality is poor and further studies are necessary to identify the best strategies to minimize risks in this group of patients.

  1. Speech profile of patients undergoing primary palatoplasty.

    Science.gov (United States)

    Menegueti, Katia Ignacio; Mangilli, Laura Davison; Alonso, Nivaldo; Andrade, Claudia Regina Furquim de

    2017-10-26

    To characterize the profile and speech characteristics of patients undergoing primary palatoplasty in a Brazilian university hospital, considering the time of intervention (early, before two years of age; late, after two years of age). Participants were 97 patients of both genders with cleft palate and/or cleft and lip palate, assigned to the Speech-language Pathology Department, who had been submitted to primary palatoplasty and presented no prior history of speech-language therapy. Patients were divided into two groups: early intervention group (EIG) - 43 patients undergoing primary palatoplasty before 2 years of age and late intervention group (LIG) - 54 patients undergoing primary palatoplasty after 2 years of age. All patients underwent speech-language pathology assessment. The following parameters were assessed: resonance classification, presence of nasal turbulence, presence of weak intraoral air pressure, presence of audible nasal air emission, speech understandability, and compensatory articulation disorder (CAD). At statistical significance level of 5% (p≤0.05), no significant difference was observed between the groups in the following parameters: resonance classification (p=0.067); level of hypernasality (p=0.113), presence of nasal turbulence (p=0.179); presence of weak intraoral air pressure (p=0.152); presence of nasal air emission (p=0.369), and speech understandability (p=0.113). The groups differed with respect to presence of compensatory articulation disorders (p=0.020), with the LIG presenting higher occurrence of altered phonemes. It was possible to assess the general profile and speech characteristics of the study participants. Patients submitted to early primary palatoplasty present better speech profile.

  2. Nanoscale steady-state temperature gradients within polymer nanocomposites undergoing continuous-wave photothermal heating from gold nanorods.

    Science.gov (United States)

    Maity, Somsubhra; Wu, Wei-Chen; Tracy, Joseph B; Clarke, Laura I; Bochinski, Jason R

    2017-08-17

    Anisotropically-shaped metal nanoparticles act as nanoscale heaters via excitation of a localized surface plasmon resonance, utilizing a photothermal effect which converts the optical energy into local heat. Steady-state temperatures within a polymer matrix embedded with gold nanorods undergoing photothermal heating using continuous-wave excitation are measured in the immediate spatial vicinity of the nanoparticle (referred to as the local temperature) from observing the rate of physical rotation of the asymmetric nanoparticles within the locally created polymer melt. Average temperatures across the entire (mostly solid) sample (referred to as the global temperature) are simultaneously observed using a fluorescence method from randomly dispersed molecular emitters. Comparing these two independent measurements in films having varying concentrations of nanorods reveals the interplay between the local and global temperatures, clearly demonstrating the capability of these material samples to sustain large steady-state spatial temperature gradients when experiencing continuous-wave excitation photothermal heating. These results are discussed quantitatively. Illustrative imaging studies of nanofibers under photothermal heating also support the presence of a large temperature gradient. Photothermal heating in this manner has potential utility in creating unique thermal processing conditions for outcomes such as driving chemical reactions, inducing crystallinity changes, or enhancing degradation processes in a manner unachievable by conventional heating methods.

  3. Anaesthesia in patients undergoing esophago-gastro-duodenoscopy for suspected bleeding

    DEFF Research Database (Denmark)

    Helsø, Ida; Risom, Martin; Vestergaard, Therese Risom

    2017-01-01

    INTRODUCTION: Upper gastrointestinal bleeding (UGIB) is a common emergency. Currently, there are no agreed guidelines on the level of anaesthetic support required in patients undergoing acute esophago-gastro-duodendoscopy (EGD). METHODS: An online questionnaire comprising 19 questions was distrib......INTRODUCTION: Upper gastrointestinal bleeding (UGIB) is a common emergency. Currently, there are no agreed guidelines on the level of anaesthetic support required in patients undergoing acute esophago-gastro-duodendoscopy (EGD). METHODS: An online questionnaire comprising 19 questions...

  4. Assessing Cardiovascular Health Using Life′s Simple 7 in a Chinese Population Undergoing Stroke Prevention

    Directory of Open Access Journals (Sweden)

    Qiong Yang

    2015-01-01

    Conclusions: Few Chinese patients undergoing stroke prevention had optimal CVH (determined using LS7. Additionally, fewer patients undergoing secondary prevention had optimal CVH than those undergoing primary prevention. In particular, physical activity and diet status in this population require improvement.

  5. Preoperative information needs of children undergoing tonsillectomy.

    LENUS (Irish Health Repository)

    Buckley, Aoife

    2012-02-01

    AIMS AND OBJECTIVES: To identify the information needs of children undergoing tonsillectomy with reference to content of information, method of delivery, information providers and timing of information provision. BACKGROUND: Tonsillectomy can be anxiety provoking for children and preoperative preparation programmes are long recognised to reduce anxiety. However, few have been designed from the perspectives of children and to date little is known about how best to prepare children in terms of what to tell them, how to convey information to them, who can best provide information and what is the best timing for information provision. DESIGN: A qualitative descriptive study. METHOD: Data were collected from nine children (aged 6-9) using interviews supported by a write and draw technique. Data were coded and categorised into themes reflecting content, method, providers and timing of information. RESULTS: Children openly communicated their information needs especially on what to tell them to expect when facing a tonsillectomy. Their principal concerns were about operation procedures, experiencing \\'soreness\\' and discomfort postoperatively and parental presence. Mothers were viewed as best situated to provide them with information. Children were uncertain about what method of information and timing would be most helpful to them. CONCLUSION: Preoperative educational interventions need to take account of children\\'s information needs so that they are prepared for surgery in ways that are meaningful and relevant to them. Future research is needed in this area. RELEVANCE TO CLINICAL PRACTICE: Practical steps towards informing children about having a tonsillectomy include asking them what they need to know and addressing their queries accordingly. Child-centred information leaflets using a question and answer format could also be helpful to children.

  6. Effect of pretreatment psoas muscle mass on survival for patients with unresectable pancreatic cancer undergoing systemic chemotherapy.

    Science.gov (United States)

    Ishii, Noriko; Iwata, Yoshinori; Nishikawa, Hiroki; Enomoto, Hirayuki; Aizawa, Nobuhiro; Ishii, Akio; Miyamoto, Yuho; Yuri, Yukihisa; Hasegawa, Kunihiro; Nakano, Chikage; Nishimura, Takashi; Yoh, Kazunori; Sakai, Yoshiyuki; Ikeda, Naoto; Takashima, Tomoyuki; Takata, Ryo; Iijima, Hiroko; Nishiguchi, Shuhei

    2017-11-01

    To the best of our knowledge, there are few previous studies that have investigated the effect of decreased skeletal muscle mass (DSMM) on survival in patients with unresectable advanced pancreatic cancer (APC) who are undergoing systemic chemotherapy. Thus, the present study aimed to investigate the impact of DSMM, as determined by the psoas muscle index (PMI) following computed tomography and prior to systemic chemotherapy, on the outcomes of patients with unresectable APC (n=61). The primary endpoint used was the overall survival (OS) rate. The OS rates in the PMI-High group (exceeds the median PMI value in each gender) were retrospectively compared with those in the PMI-Low group (below the median PMI value in each gender), and factors associated with OS were investigated using univariate and multivariate analyses. The study cohort included 31 male and 30 female patients with a median age of 72 years, 13 of whom were stage IVA, and 48 were stage IVB. The median PMI in males was 4.3 cm 2 /m 2 (range, 1.6-8.2 cm 2 /m 2 ), while that in females was 2.3 cm 2 /m 2 (range, 0.7-6.1 cm 2 /m 2 ). The proportion of patients with performance status 0 in the PMI-High group was significantly high, compared with that in the PMI-Low group [83.3% (25/30) vs. 58.1% (18/31); P=0.0486]. Body mass index in the PMI-High group was significantly higher compared with that in the PMI-Low group (P=0.0154). The 1-year cumulative survival rate was 43.3% in the PMI-High group and 12.9% in the PMI-Low group (P=0.0027). Following multivariate analysis, PMI (P=0.0036), prothrombin time (P=0.0044) and carbohydrate antigen 19-9 (P=0.0451) were identified to be significant predictors of OS. In conclusion, DSMM, as determined by the PMI, could be a significant predictor of prognosis in patients with unresectable APC who are receiving systemic chemotherapy.

  7. Descriptions of reference LWR facilities for analysis of nuclear fuel cycles

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, K.J.; Kabele, T.J.

    1979-09-01

    To contribute to the Department of Energy's identification of needs for improved environmental controls in nuclear fuel cycles, a study was made of a light water reactor system. A reference LWR fuel cycle was defined, and each step in this cycle was characterized by facility description and mainline and effluent treatment process performance. The reference fuel cycle uses fresh uranium in light water reactors. Final treatment and ultimate disposition of waste from the fuel cycle steps were not included, and the waste is assumed to be disposed of by approved but currently undefined means. The characterization of the reference fuel cycle system is intended as basic information for further evaluation of alternative effluent control systems.

  8. Descriptions of reference LWR facilities for analysis of nuclear fuel cycles

    International Nuclear Information System (INIS)

    Schneider, K.J.; Kabele, T.J.

    1979-09-01

    To contribute to the Department of Energy's identification of needs for improved environmental controls in nuclear fuel cycles, a study was made of a light water reactor system. A reference LWR fuel cycle was defined, and each step in this cycle was characterized by facility description and mainline and effluent treatment process performance. The reference fuel cycle uses fresh uranium in light water reactors. Final treatment and ultimate disposition of waste from the fuel cycle steps were not included, and the waste is assumed to be disposed of by approved but currently undefined means. The characterization of the reference fuel cycle system is intended as basic information for further evaluation of alternative effluent control systems

  9. [Reference citation].

    Science.gov (United States)

    Brkić, Silvija

    2013-01-01

    Scientific and professional papers represent the information basis for scientific research and professional work. References important for the paper should be cited within the text, and listed at the end of the paper. This paper deals with different styles of reference citation. Special emphasis was placed on the Vancouver Style for reference citation in biomedical journals established by the International Committee of Medical Journal Editors. It includes original samples for citing various types of articles, both printed and electronic, as well as recommendations related to reference citation in accordance with the methodology and ethics of scientific research and guidelines for preparing manuscripts for publication.

  10. Reference values for the CAVIPRES-30 questionnaire, a global questionnaire on the health-related quality of life of patients with prostate cancer.

    Science.gov (United States)

    Gómez-Veiga, F; Silmi-Moyano, A; Günthner, S; Puyol-Pallas, M; Cózar-Olmo, J M

    2014-06-01

    Define and establish the reference values of the CAVIPRES-30 Questionnaire, a health related quality of life questionnaire specific for prostate cancer patients. The CAVIPRES-30 was administered to 2,630 males with prostate cancer included by 238 Urologist belonging to the Spanish National Healthcare System. Descriptive analysis on socio-demographic and clinical data were performed, and multivariate analyses were used to corroborate that stratification variables were statistically significantly and independently associated to the overall score of the questionnaire. The variables Time since diagnosis of the illness, whether the patient had a Stable partner or not, if he was, or not, undergoing Symptomatic treatment were statistically significantly and independently associated (P < .001) to the overall score of the questionnaire. The reference values table of the CAVIPRES-30 questionnaire is made up of different kinds of information of each patient profile: sample size, descriptive statistics with regard to the overall score, Cronbach's alpha value (between .791 and .875) and the questionnaire's values are reported by deciles. The results of this study contribute new proof as to the suitability and usefulness of the CAVIPRES-30 questionnaire as an instrument for assessing individually the quality of life of prostate cancer. Copyright © 2013 AEU. Published by Elsevier Espana. All rights reserved.

  11. The project manager's desk reference: project planning, schedulding, evaluation, control, systems

    National Research Council Canada - National Science Library

    Lewis, James P

    2007-01-01

    In this Third Edition of The Project Manager's Desk Reference, top project management consultant James Lewis arms you with today's most comprehensive and understandable project management resources...

  12. Mounting system for optical frequency reference cavities

    Science.gov (United States)

    Notcutt, Mark (Inventor); Hall, John L. (Inventor); Ma, Long-Sheng (Inventor)

    2008-01-01

    A technique for reducing the vibration sensitivity of laser-stabilizing optical reference cavities is based upon an improved design and mounting method for the cavity, wherein the cavity is mounted vertically. It is suspended at one plane, around the spacer cylinder, equidistant from the mirror ends of the cavity. The suspension element is a collar of an extremely low thermal expansion coefficient material, which surrounds the spacer cylinder and contacts it uniformly. Once the collar has been properly located, it is cemented in place so that the spacer cylinder is uniformly supported and does not have to be squeezed at all. The collar also includes a number of cavities partially bored into its lower flat surface, around the axial bore. These cavities are support points, into which mounting base pins will be inserted. Hence the collar is supported at a minimum of three points.

  13. Quantum frames of reference

    International Nuclear Information System (INIS)

    Kaufherr, T.

    1981-01-01

    The idea that only relative variables have physical meaning came to be known as Mach's principle. Carrying over this idea to quantum theory, has led to the consideration of finite mass, macroscopic reference frames, relative to which all physical quantities are measured. During the process of measurement, a finite mass observer receives a kickback, and this reaction of the measuring device is not negligible in quantum theory because of the quantization of the action. Hence, the observer himself has to be included in the system that is being considered. Using this as the starting point, a number of thought experiments involving finite mass observers is discussed which have quantum uncertainties in their time or in their position. These thought experiments serve to elucidate in a qualitative way some of the difficulties involved, as well as pointing out a direction to take in seeking solutions to them. When the discussion is extended to include more than one observer, the question of the covariance of the theory immediately arises. Because none of the frames of reference should be preferred, the theory should be covariant. This demand expresses an equivalence principle which here is extended to include reference frames which are in quantum uncertainties relative to each other. Formulating the problem in terms of canonical variables, the ensueing free Hamiltonian contains vector and scalar potentials which represent the kick that the reference frame receives during measurement. These are essentially gravitational type potentials, resulting, as it were, from the extension of the equivalence principle into the quantum domain

  14. Mortality Among Patients with Pleural Effusion Undergoing Thoracentesis

    Science.gov (United States)

    DeBiasi, Erin M.; Pisani, Margaret A.; Murphy, Terrence E.; Araujo, Katy; Kookoolis, Anna; Argento, A Christine; Puchalski, Jonathan

    2016-01-01

    Background Of the 1.5 million people diagnosed with pleural effusion annually in the U.S., approximately 178,000 undergo thoracentesis. While it is known that malignant pleural effusion portends a poor prognosis, mortality of patients with nonmalignant effusions has not been well studied. Methods This prospective cohort study evaluated 308 patients undergoing thoracentesis. Chart review was performed to obtain baseline characteristics. The etiology of the effusions was determined using standardized criteria. Mortality was determined at 30-days and 1-year. Results 247 unilateral and 61 bilateral thoracenteses were performed. Malignant effusion had the highest 30-day (37%) and 1 year (77%) mortality. There was substantial patient 30-day and 1-year mortality with effusions due to multiple benign etiologies (29% and 55%), CHF (22% and 53%), and renal failure (14% and 57%). Patients with bilateral pleural effusion, relative to unilateral, were associated with higher risk of death at 30 days and 1 year (17% versus 47%; HR 2.58 CI [1.44–4.63] and 36% versus 69%; HR 2.32 CI [1.55–3.48]). Conclusions Patients undergoing thoracentesis for pleural effusion have high short and long-term mortality. Patients with malignant effusion had the highest mortality followed by multiple benign etiologies, CHF and renal failure. Bilateral pleural effusion is distinctly associated with high mortality. PMID:25837039

  15. Project summary plan for HTGR recycle reference facility

    International Nuclear Information System (INIS)

    Baxter, B.J.

    1979-11-01

    A summary plan is introduced for completing conceptual definition of an HTGR Recycle Reference Facility (HRRF). The plan describes a generic project management concept, often referred to as the requirements approach to systems engineering. The plan begins with reference flow sheets and provides for the progressive evolution of HRRF requirements and definition through feasibility, preconceptual, and conceptual phases. The plan lays end-to-end all the important activities and elements to be treated during each phase of design. Identified activities and elements are further supported by technical guideline documents, which describe methodology, needed terminology, and where relevant a worked example

  16. REFERENCE MATERIALS IN THE SPHERE OF USE OF ATOMIC ENERGY

    Directory of Open Access Journals (Sweden)

    V. A. Borisov

    2015-01-01

    Full Text Available The article describes the chronology of development of the system of reference materials in the nuclear industry of the Russian Federation. The basic documents used in the sphere of nuclear energy are described. The nomenclature of reference materials and feature of their application in the "Rosatom" is given. The prospects of development activities in the field of reference materials are formulated.

  17. Considerations for reference pump curves

    International Nuclear Information System (INIS)

    Stockton, N.B.

    1992-01-01

    This paper examines problems associated with inservice testing (IST) of pumps to assess their hydraulic performance using reference pump curves to establish acceptance criteria. Safety-related pumps at nuclear power plants are tested under the American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code (the Code), Section 11. The Code requires testing pumps at specific reference points of differential pressure or flow rate that can be readily duplicated during subsequent tests. There are many cases where test conditions cannot be duplicated. For some pumps, such as service water or component cooling pumps, the flow rate at any time depends on plant conditions and the arrangement of multiple independent and constantly changing loads. System conditions cannot be controlled to duplicate a specific reference value. In these cases, utilities frequently request to use pump curves for comparison of test data for acceptance. There is no prescribed method for developing a pump reference curve. The methods vary and may yield substantially different results. Some results are conservative when compared to the Code requirements; some are not. The errors associated with different curve testing techniques should be understood and controlled within reasonable bounds. Manufacturer's pump curves, in general, are not sufficiently accurate to use as reference pump curves for IST. Testing using reference curves generated with polynomial least squares fits over limited ranges of pump operation, cubic spline interpolation, or cubic spline least squares fits can provide a measure of pump hydraulic performance that is at least as accurate as the Code required method. Regardless of the test method, error can be reduced by using more accurate instruments, by correcting for systematic errors, by increasing the number of data points, and by taking repetitive measurements at each data point

  18. Opportunistic microorganisms in patients undergoing antibiotic therapy for pulmonary tuberculosis

    Directory of Open Access Journals (Sweden)

    Silvia Maria Rodrigues Querido

    2011-12-01

    Full Text Available Antimicrobial therapy may cause changes in the resident oral microbiota, with the increase of opportunistic pathogens. The aim of this study was to compare the prevalence of Candida, Staphylococcus, Pseudomonas and Enterobacteriaceae in the oral cavity of fifty patients undergoing antibiotic therapy for pulmonary tuberculosis and systemically healthy controls. Oral rinsing and subgingival samples were obtained, plated in Sabouraud dextrose agar with chloramphenicol, mannitol agar and MacConkey agar, and incubated for 48 h at 37ºC. Candida spp. and coagulase-positive staphylococci were identified by phenotypic tests, C. dubliniensis, by multiplex PCR, and coagulase-negative staphylococci, Enterobacteriaceae and Pseudomonas spp., by the API systems. The number of Candida spp. was significantly higher in tuberculosis patients, and C. albicans was the most prevalent specie. No significant differences in the prevalence of other microorganisms were observed. In conclusion, the antimicrobial therapy for pulmonary tuberculosis induced significant increase only in the amounts of Candida spp.

  19. VBScript pocket reference

    CERN Document Server

    Lomax, Paul; Petrusha, Ron

    2008-01-01

    Microsoft's Visual Basic Scripting Edition (VBScript), a subset of Visual Basic for Applications, is a powerful language for Internet application development, where it can serve as a scripting language for server-side, client-side, and system scripting. Whether you're developing code for Active Server Pages, client-side scripts for Internet Explorer, code for Outlook forms, or scripts for Windows Script Host, VBScript Pocket Reference will be your constant companion. Don't let the pocket-friendly format fool you. Based on the bestsellingVBScript in a Nutshell, this small book details every V

  20. A reference aerosol for a radon reference chamber

    Science.gov (United States)

    Paul, Annette; Keyser, Uwe

    1996-02-01

    The measurement of radon and radon progenies and the calibration of their detection systems require the production and measurement of aerosols well-defined in size and concentration. In the German radon reference chamber, because of its unique chemical and physical properties, carnauba wax is used to produce standard aerosols. The aerosol size spectra are measured on-line by an aerosol measurement system in the range of 10 nm to 1 μm aerodynamic diameter. The experimental set-ups for the study of adsorption of radioactive ions on aerosols as function of their size and concentration will be described, the results presented and further adaptations for an aerosol jet introduced (for example, for the measurement of short-lived neutron-rich isotopes). Data on the dependence of aerosol radius, ion concentration and element selectivity is collected by using a 252Cf-sf source. The fission products of this source range widely in elements, isotopes and charges. Adsorption and the transport of radioactive ions on aerosols have therefore been studied for various ions for the first time, simultaneously with the aerosol size on-line spectrometry.

  1. A reference aerosol for a radon reference chamber

    Energy Technology Data Exchange (ETDEWEB)

    Paul, A. [Physikalisch-Technische Bundesanstalt, Braunschweig (Germany); Keyser, U. [Physikalisch-Technische Bundesanstalt, Braunschweig (Germany)

    1996-01-11

    The measurement of radon and radon progenies and the calibration of their detection systems require the production and measurement of aerosols well-defined in size and concentration. In the German radon reference chamber, because of its unique chemical and physical properties, carnauba wax is used to produce standard aerosols. The aerosol size spectra are measured on-line by an aerosol measurement system in the range of 10 nm to 1 {mu}m aerodynamic diameter. The experimental set-ups for the study of adsorption of radioactive ions on aerosols as function of their size and concentration are described, the results presented and further adaptations for an aerosol jet introduced (for example, for the measurement of short-lived neutron-rich isotopes). Data on the dependence of aerosol radius, ion concentration and element selectivity is collected by using a {sup 252}Cf-sf source. The fission products of this source range widely in elements, isotopes and charges. Adsorption and the transport of radioactive ions on aerosols have therefore been studied for various ions for the first time, simultaneously with the aerosol size on-line spectrometry. (orig.).

  2. Preoperative B-type natriuretic peptides in patients undergoing ...

    African Journals Online (AJOL)

    Southern African Journal of Anaesthesia and Analgesia ... Preoperative B-type natriuretic peptides in patients undergoing noncardiac surgery: a cumulative ... Future investigation should focus on the clinical implications of these data and the ...

  3. Clinical Validation of the 2005 ISUP Gleason Grading System in a Cohort of Intermediate and High Risk Men Undergoing Radical Prostatectomy.

    Directory of Open Access Journals (Sweden)

    Sheila F Faraj

    Full Text Available In 2005, the International Society of Urological Pathology (ISUP introduced several modifications to the original Gleason system that were intended to enhance the prognostic power of Gleason score (GS. The objective of this study was to clinically validate the 2005 ISUP Gleason grading system for its ability to detect metastasis. We queried our institutional RP database for men with NCCN clinically localized intermediate to high-risk disease undergoing radical prostatectomy (RP between 1992 and 2010 with no additional treatment until the time of metastatic progression. A case-cohort design was utilized. A total of 333 available RP samples were re-reviewed and GS was reassigned per the 2005 ISUP Gleason system. Cumulative incidence of metastasis was 0%, 8.4%, 24.5% and 44.4% among specimens that were downgraded, unchanged, had one point GS increase and two point GS increase, respectively. The hazard ratio for metastasis raised in GS 8 and 9 compared to GS 7 from 2.77 and 5.91 to 3.49 and 9.31, respectively. The survival c-index of GS increased from 0.70 to 0.80 when samples were re-graded at 5 years post RP. The c-index of the reassigned GS was higher than the original GS (0.77 vs 0.64 for predicting PCSM at 10 years post RP. The regraded GS improved the prediction of metastasis and PCSM. This validates the updated Gleason grading system using an unambiguous clinical endpoint and highlights the need for reassignment of Gleason grading according to 2005 ISUP system when considering comparisons of novel biomarkers to clinicopathological variables in archival cohorts.

  4. Postural Stability Evaluation of Patients Undergoing Vestibular Schwannoma Microsurgery Employing the Inertial Measurement Unit

    Directory of Open Access Journals (Sweden)

    Patrik Kutilek

    2018-01-01

    Full Text Available The article focuses on a noninvasive method and system of quantifying postural stability of patients undergoing vestibular schwannoma microsurgery. Recent alternatives quantifying human postural stability are rather limited. The major drawback is that the posturography system can evaluate only two physical quantities of body movement and can be measured only on a transverse plane. A complex movement pattern can be, however, described more precisely while using three physical quantities of 3-D movement. This is the reason why an inertial measurement unit (Xsens MTx unit, through which we obtained 3-D data (three Euler angles or three orthogonal accelerations, was placed on the patient’s trunk. Having employed this novel method based on the volume of irregular polyhedron of 3-D body movement during quiet standing, it was possible to evaluate postural stability. To identify and evaluate pathological balance control of patients undergoing vestibular schwannoma microsurgery, it was necessary to calculate the volume polyhedron using the 3-D Leibniz method and to plot three variables against each other. For the needs of this study, measurements and statistical analysis were made on nine patients. The results obtained by the inertial measurement unit showed no evidence of improvement in postural stability shortly after surgery (4 days. The results were consistent with the results obtained by the posturography system. The evaluated translation variables (acceleration and rotary variables (angles measured by the inertial measurement unit correlate strongly with the results of the posturography system. The proposed method and application of the inertial measurement unit for the purpose of measuring patients with vestibular schwannoma appear to be suitable for medical practice. Moreover, the inertial measurement unit is portable and, when compared to other traditional posturography systems, economically affordable. Inertial measurement units can

  5. Stress modeling in colloidal dispersions undergoing non-viscometric flows

    Science.gov (United States)

    Dolata, Benjamin; Zia, Roseanna

    2017-11-01

    We present a theoretical study of the stress tensor for a colloidal dispersion undergoing non-viscometric flow. In such flows, the non-homogeneous suspension stress depends on not only the local average total stresslet-the sum of symmetric first moments of both the hydrodynamic traction and the interparticle force-but also on the average quadrupole, octupole, and higher-order moments. To compute the average moments, we formulate a six dimensional Smoluchowski equation governing the microstructural evolution of a suspension in an arbitrary fluid velocity field. Under the conditions of rheologically slow flow, where the Brownian relaxation of the particles is much faster than the spatiotemporal evolution of the flow, the Smoluchowski equation permits asymptotic solution, revealing a suspension stress that follows a second-order fluid constitutive model. We obtain a reciprocal theorem and utilize it to show that all constitutive parameters of the second-order fluid model may be obtained from two simpler linear-response problems: a suspension undergoing simple shear and a suspension undergoing isotropic expansion. The consequences of relaxing the assumption of rheologically slow flow, including the appearance of memory and microcontinuum behaviors, are discussed.

  6. Thyroid dose measurement in patients undergoing to digital orthopantomography using optical stimulation dosimeters

    International Nuclear Information System (INIS)

    Gutierrez M, J. G.; Lopez V, A.; Rivera M, T.; Avalos P, L. Y.

    2016-10-01

    In this paper we present the study of the thyroid equivalent dose in 300 patients undergoing to digital orthopantomography for dental treatment purposes using optical stimulation dosimeters (OSL) as in-vivo dosimeters, in order to verify if this is within acceptable parameters to prevent stochastic risks and to evaluate the possible risks caused by the technique used for this type of study (66 kv, 5 m A, 14.1 s). Three OSL dosimeters were used per patient, which were placed by the physician on the skin above the thyroid gland (using anatomical references and palpation); the information of the patients was divided by neck size and sex, finding a slight increase in the equivalent dose for female and small size patient, this combination being the group that was submitted to a higher dose. The results obtained were compared with similar studies performed on anthropomorphic mannequins with TLD dosimeters obtaining lower results. The equivalent dose found even though is below the threshold stochastic damage must be motorized for radiological protection and registration purposes. (Author)

  7. Diagnostic reference levels and complexity indices in interventional radiology: a national programme

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz-Cruces, R.; Perez-Martinez, M.; Pastor-Vega, J.M.; Canete, S. [University of Malaga, School of Medicine, Malaga (Spain); Vano, E.; Fernandez-Soto, J.M.; Sanchez-Casanueva, R.; Gallego-Beuter, J.J. [Complutense University, San Carlos Hospital, Medical School, Madrid (Spain); Carrera-Magarino, F.; Moreno-Rodriguez, F.; Moreno-Sanchez, T. [Juan Ramon Jimenez University Hospital, Huelva (Spain); Soler-Cantos, M.M.; Canis-Lopez, M. [Reina Sofia University Hospital, Cordoba (Spain); Hernandez-Armas, J.; Diaz-Romero, F.J. [University Hospital of Canary Islands, Tenerife (Spain); Rosales-Espizua, F.; Lopez-Medina, A.; Gonzalez-de-Garay, M. [Basurto Hospital, Bilbao (Spain); Martin-Palanca, A. [Virgen de la Victoria University Hospital, Malaga (Spain); Gil-Agudo, A.; Zarca-Diaz, M.A.; Zapata-Jimenez, J.C. [General University Hospital, Ciudad Real (Spain); Parra-Osorio, V.; Munoz Ruiz-Canela, J.J.; Moreno-Saiz, C.; Galan-Montenegro, P. [Carlos Haya University Hospital, Malaga (Spain)

    2016-12-15

    To propose national diagnostic reference levels (DRLs) for interventional radiology and to evaluate the impact of the procedural complexity on patient doses. Eight interventional radiology units from Spanish hospitals were involved in this project. The participants agreed to undergo common quality control procedures for X-ray systems. Kerma area product (KAP) was collected from a sample of 1,649 procedures. A consensus document established the criteria to evaluate the complexity of seven types of procedures. DRLs were set as the 3rd quartile of KAP values. The KAP (3rd quartile) in Gy cm{sup 2} for the procedures included in the survey were: lower extremity arteriography (n = 784) 78; renal arteriography (n = 37) 107; transjugular hepatic biopsies (THB) (n = 30) 45; biliary drainage (BD) (n = 314) 30; uterine fibroid embolization (UFE) (n = 56) 214; colon endoprostheses (CE) (n = 31) 169; hepatic chemoembolization (HC) (n = 269) 303; femoropopliteal revascularization (FR) (n = 62) 119; and iliac stent (n = 66) 170. The complexity involved the increases in the following KAP factors from simple to complex procedures: THB x4; BD x13; UFE x3; CE x3; HC x5; FR x5 and IS x4. The evaluation of the procedure complexity in patient doses will allow the proper use of DRLs for the optimization of interventional radiology. (orig.)

  8. Rosuvastatin and cardiovascular events in patients undergoing hemodialysis

    DEFF Research Database (Denmark)

    Fellström, Bengt C; Jardine, Alan G; Schmieder, Roland E

    2009-01-01

    . Secondary end points included death from all causes and individual cardiac and vascular events. RESULTS: After 3 months, the mean reduction in low-density lipoprotein (LDL) cholesterol levels was 43% in patients receiving rosuvastatin, from a mean baseline level of 100 mg per deciliter (2.6 mmol per liter......BACKGROUND: Statins reduce the incidence of cardiovascular events in patients at high cardiovascular risk. However, a benefit of statins in such patients who are undergoing hemodialysis has not been proved. METHODS: We conducted an international, multicenter, randomized, double-blind, prospective...... trial involving 2776 patients, 50 to 80 years of age, who were undergoing maintenance hemodialysis. We randomly assigned patients to receive rosuvastatin, 10 mg daily, or placebo. The combined primary end point was death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke...

  9. A First Look at the Upcoming SISO Space Reference FOM

    Science.gov (United States)

    Mueller, Bjorn; Crues, Edwin Z.; Dexter, Dan; Garro, Alfredo; Skuratovskiy, Anton; Vankov, Alexander

    2016-01-01

    Spaceflight is difficult, dangerous and expensive; human spaceflight even more so. In order to mitigate some of the danger and expense, professionals in the space domain have relied, and continue to rely, on computer simulation. Simulation is used at every level including concept, design, analysis, construction, testing, training and ultimately flight. As space systems have grown more complex, new simulation technologies have been developed, adopted and applied. Distributed simulation is one those technologies. Distributed simulation provides a base technology for segmenting these complex space systems into smaller, and usually simpler, component systems or subsystems. This segmentation also supports the separation of responsibilities between participating organizations. This segmentation is particularly useful for complex space systems like the International Space Station (ISS), which is composed of many elements from many nations along with visiting vehicles from many nations. This is likely to be the case for future human space exploration activities. Over the years, a number of distributed simulations have been built within the space domain. While many use the High Level Architecture (HLA) to provide the infrastructure for interoperability, HLA without a Federation Object Model (FOM) is insufficient by itself to insure interoperability. As a result, the Simulation Interoperability Standards Organization (SISO) is developing a Space Reference FOM. The Space Reference FOM Product Development Group is composed of members from several countries. They contribute experiences from projects within NASA, ESA and other organizations and represent government, academia and industry. The initial version of the Space Reference FOM is focusing on time and space and will provide the following: (i) a flexible positioning system using reference frames for arbitrary bodies in space, (ii) a naming conventions for well-known reference frames, (iii) definitions of common time scales

  10. An Excel-Based System to Manage Radiation Safety for the Family of Patients Undergoing 131I Therapy.

    Science.gov (United States)

    Steward, Palmer G

    2017-06-01

    The purpose of this study was to develop spreadsheet workbooks that assist in the radiation safety counseling of 131 I therapy patients and their families, providing individualized guidelines that avoid imposing overly conservative restrictions on family members and others. Methods: The mathematic model included biphasic patient radionuclide retention. The extrathyroidal component was a cylindric volume with a diameter corresponding to the patient's size and included patient self-absorption, whereas the thyroidal component was a point source whose transmission was reduced by self-absorption. A separate model in which the thyroid, extrathyroid, and bladder compartments fed serially from one to the next was developed to depict the radionuclide levels within the patient and to estimate the activity entering the environment at each urination. Results: The system was organized into a set of 4 workbooks: the first to be used with ablation patients prepared using thyrogen, the second with ablation patients prepared by deprivation, the third with hyperthyroid patients, and the fourth with the unusual hyperthyroid patient who finds the restrictions to be oppressive and returns 5-10 d after administration for a measurement and reassessment. The workbooks evaluated the radiation field strength external to the patient and indicated restrictions based on selected dose limits. To assist physicians in suggesting contamination precautions, the workbooks also evaluated the radioactivity present within the patient and the estimated discharge into the environment as a function of time. Conclusion: The workbooks that were developed assist the radiation safety counselor in individualizing radiation protection procedures for the family of patients undergoing 131 I therapy. The workbook system avoids overly conservative assumptions while permitting selection of appropriate dose limits for each individual. © 2017 by the Society of Nuclear Medicine and Molecular Imaging.

  11. Compilation of references, data sources and analysis methods for LMFBR primary piping system components

    International Nuclear Information System (INIS)

    Reich, M.; Esztergar, E.P.; Ellison, E.G.; Erdogan, F.; Gray, T.G.F.; Wells, C.W.

    1977-03-01

    A survey and review program for application of fracture mechanics methods in elevated temperature design and safety analysis has been initiated in December of 1976. This is the first of a series of reports, the aim of which is to provide a critical review of the theories of fracture and the application of fracture mechanics methods to life prediction, reliability and safety analysis of piping components in nuclear plants undergoing sub-creep and elevated temperature service conditions

  12. Long-term pavement performance ancillary information management system (AIMS) reference guide.

    Science.gov (United States)

    2012-11-01

    This document provides information on the Long-Term Pavement Performance (LTPP) program ancillary information. : Ancillary information includes data, images, reference materials, resource documents, and other information that : support and extend the...

  13. A structural SVM approach for reference parsing.

    Science.gov (United States)

    Zhang, Xiaoli; Zou, Jie; Le, Daniel X; Thoma, George R

    2011-06-09

    Automated extraction of bibliographic data, such as article titles, author names, abstracts, and references is essential to the affordable creation of large citation databases. References, typically appearing at the end of journal articles, can also provide valuable information for extracting other bibliographic data. Therefore, parsing individual reference to extract author, title, journal, year, etc. is sometimes a necessary preprocessing step in building citation-indexing systems. The regular structure in references enables us to consider reference parsing a sequence learning problem and to study structural Support Vector Machine (structural SVM), a newly developed structured learning algorithm on parsing references. In this study, we implemented structural SVM and used two types of contextual features to compare structural SVM with conventional SVM. Both methods achieve above 98% token classification accuracy and above 95% overall chunk-level accuracy for reference parsing. We also compared SVM and structural SVM to Conditional Random Field (CRF). The experimental results show that structural SVM and CRF achieve similar accuracies at token- and chunk-levels. When only basic observation features are used for each token, structural SVM achieves higher performance compared to SVM since it utilizes the contextual label features. However, when the contextual observation features from neighboring tokens are combined, SVM performance improves greatly, and is close to that of structural SVM after adding the second order contextual observation features. The comparison of these two methods with CRF using the same set of binary features show that both structural SVM and CRF perform better than SVM, indicating their stronger sequence learning ability in reference parsing.

  14. Factors That Influence the Decision to Undergo Labiaplasty: Media, Relationships, and Psychological Well-Being.

    Science.gov (United States)

    Sharp, Gemma; Tiggemann, Marika; Mattiske, Julie

    2016-04-01

    An increasing number of women are undergoing labiaplasty procedures; however, very little is known about the psychological factors that motivate women to seek out this procedure. To investigate the factors that influence women's decisions to undergo labiaplasty. Women seeking to undergo labiaplasty (n = 35) were compared with women who were not (n = 30). Standardized measures were employed to assess the patients' media exposure (television, the Internet, advertising, pornography), relationship quality, and psychological well-being. Women's motivations for deciding to undergo a labiaplasty procedure were characterized as "appearance," "functional," "sexual," or "psychological" motivations, with concerns about the labia's appearance being the most commonly reported motivation. Correspondingly, women seeking labiaplasty were significantly less satisfied with the appearance of their genitals than the comparison group (P media exposure and relationship status as important factors that influence women's decisions to undergo labiaplasty. 3 Risk. © 2016 The American Society for Aesthetic Plastic Surgery, Inc. Reprints and permission: journals.permissions@oup.com.

  15. A Reference Model for Virtual Machine Launching Overhead

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Hao; Ren, Shangping; Garzoglio, Gabriele; Timm, Steven; Bernabeu, Gerard; Chadwick, Keith; Noh, Seo-Young

    2016-07-01

    Cloud bursting is one of the key research topics in the cloud computing communities. A well designed cloud bursting module enables private clouds to automatically launch virtual machines (VMs) to public clouds when more resources are needed. One of the main challenges in developing a cloud bursting module is to decide when and where to launch a VM so that all resources are most effectively and efficiently utilized and the system performance is optimized. However, based on system operational data obtained from FermiCloud, a private cloud developed by the Fermi National Accelerator Laboratory for scientific workflows, the VM launching overhead is not a constant. It varies with physical resource utilization, such as CPU and I/O device utilizations, at the time when a VM is launched. Hence, to make judicious decisions as to when and where a VM should be launched, a VM launching overhead reference model is needed. In this paper, we first develop a VM launching overhead reference model based on operational data we have obtained on FermiCloud. Second, we apply the developed reference model on FermiCloud and compare calculated VM launching overhead values based on the model with measured overhead values on FermiCloud. Our empirical results on FermiCloud indicate that the developed reference model is accurate. We believe, with the guidance of the developed reference model, efficient resource allocation algorithms can be developed for cloud bursting process to minimize the operational cost and resource waste.

  16. NEURO-SYSTEM OF AIMING AND STABILIZING WITH A REGULATOR ON THE BASIS OF STANDARD MODEL MODEL REFERENCE CONTROLLER

    Directory of Open Access Journals (Sweden)

    B.I. Kuznetsov

    2015-08-01

    Full Text Available The aim of this work is the synthesis of neural network aiming and stabilization system for the special equipment of moving objects with neuro-controller on the basis of standard model and performance comparison of the neural network system with the neural network predictive control. Build a block diagram of the neural network aiming and stabilization system, based on the subject control principle with PD-regulator in the position loop and with neuro-controller on the basis of standard model in the in the velocity loop. The neuro-controller on the basis of standard model Model Reference Controller is synthesized in the MATLAB Neural Network Toolbox and system simulation is performed. The studies show that the transient state variables of the system are oscillatory. Therefore, the neuro-controller with the prediction NN Predictive Controller should be used for aiming and stabilizing system to provide high dynamic characteristics achieved at the cost of higher complexity and computational cost.

  17. A systematic review of exercise and psychosocial rehabilitation interventions to improve health-related outcomes in patients with bladder cancer undergoing radical cystectomy.

    Science.gov (United States)

    Rammant, Elke; Decaestecker, Karel; Bultijnck, Renée; Sundahl, Nora; Ost, Piet; Pauwels, Nele S; Deforche, Benedicte; Pieters, Ronny; Fonteyne, Valérie

    2018-05-01

    Summarizing the evidence on the effects of pre- and postoperative exercise and psychosocial rehabilitation interventions on patient-reported outcomes (PROs) and physical fitness in bladder cancer patients undergoing radical cystectomy. The Cochrane Central Register of Controlled Trials, MEDLINE, Embase, Web of Science and the Physiotherapy Evidence Database were searched independently by two authors from inception until 10 November 2017. Cited references of the studies and citing references retrieved via Web of Science were also checked. Randomized controlled trials (RCTs) and non-randomized studies assessing effects of exercise and psychosocial interventions in bladder cancer patients undergoing radical cystectomy were eligible. Primary outcome measures were PROs and physical fitness. Risk of bias was assessed using the Cochrane Collaboration tool and the Newcastle-Ottawa Scale. Five RCTs (three exercise and two psychosocial studies) and one non-randomized psychosocial study comprising 317 bladder cancer patients were included. Timing of the intervention was preoperative ( n = 2), postoperative ( n = 2) or both pre- and postoperative ( n = 2). Positive effects of exercise were found for physical fitness ( n = 3), some health-related quality-of-life (HRQoL) domains ( n = 2), personal activities in daily living ( n = 1) and muscle strength ( n = 1). Psychosocial interventions showed positive effects on anxiety ( n = 1), fatigue ( n = 1), depression ( n = 1), HRQoL ( n = 1) and posttraumatic growth ( n = 1). Quality assessment showed most shortcomings with sample sizes and strong heterogeneity was observed between studies. The evidence relating to the effects of exercise in bladder cancer is very limited and is even less for psychosocial interventions.

  18. Towards dynamic reference information models: Readiness for ICT mass customisation

    NARCIS (Netherlands)

    Verdouw, C.N.; Beulens, A.J.M.; Trienekens, J.H.; Verwaart, D.

    2010-01-01

    Current dynamic demand-driven networks make great demands on, in particular, the interoperability and agility of information systems. This paper investigates how reference information models can be used to meet these demands by enhancing ICT mass customisation. It was found that reference models for

  19. Describing, Instantiating and Evaluating a Reference Architecture : A Case Study

    NARCIS (Netherlands)

    Avgeriou, Paris

    2003-01-01

    The result of a domain maturing is the emergence of reference architectures that offer numerous advantages to software architects and other stakeholders. However there is no straightforward way to describe a reference architecture and in sequence to design instances for specific systems, while at

  20. Impact of multimodal preoperative preparation program on children undergoing surgery

    Directory of Open Access Journals (Sweden)

    Priya Reshma Aranha

    2017-01-01

    Full Text Available Background: The advanced era of technological development in child health care has resulted in more pediatric procedures being performed in various settings. Millions of children undergo surgery every year which is a stressful event. Many nonpharmacological strategies are being used to manage the preoperative fear and anxiety in children. The current study aims to assess the effectiveness of multimodal preoperative preparation program (MPPP on children undergoing surgery in terms of its effect on the psychophysiological parameters. Objective: The aim of this study is to assess the effectiveness of MPPP on the psychophysiological parameters of children undergoing surgery. Materials and Methods: A quasi-experimental study was conducted in a selected multi-specialty hospital. Using the purposive sampling technique, a total of 110 children aged 8–12 years were assigned to nonintervention (n = 55 and intervention (n = 55 groups, respectively. The MPPP was administered to the intervention group. The children in the nonintervention group received the routine preoperative care. Child's fear and anxiety was assessed on admission, prior to shifting the child to operation theater (OT, 24 and 48 h after surgery, whereas child's pulse, respiration, blood pressure (BP, and oxygen saturation was assessed on admission, prior to shifting the child to OT, 6, 12, 24, and 48 h after surgery and pain was assessed at 24 and 48 h after surgery. Results: The mean fear and anxiety scores of children were significantly lower in the intervention group than that of nonintervention group (P 0.05. This study also found that there is a significant association between the psychophysiological parameters of children with the selected demographic variables (P < 0.05. A positive correlation was found between the psychological and physiological parameters of children undergoing surgery. Conclusion: The MPPP is effective on psychophysiological parameters of children undergoing

  1. A Wireless Swing Angle Measurement Scheme Using Attitude Heading Reference System Sensing Units Based on Microelectromechanical Devices

    Directory of Open Access Journals (Sweden)

    Bingtuan Gao

    2014-11-01

    Full Text Available Feasible real-time swing angle measurement is significant to improve the efficiency and safety of industrial crane systems. This paper presents a wireless microelectromechanical system (MEMS-based swing angle measurement system. The system consists of two attitude heading reference system (AHRS sensing units with a wireless communication function, which are mounted on the hook (or payload and the jib (or base of the crane, respectively. With a combination of a three-axis accelerometer, a three-axis gyroscope and a three-axis magnetometer, the standard extended Kalman filter (EKF is used to estimate the desired orientation of the payload and the base. Wireless ZigBee communication is employed to transmit the orientation of the payload to the sensing unit mounted on the base, which measures the orientation of the base. Because several physical parameters from the payload to the base can be acquired from the original crane control system, the swing angles of the payload can be calculated based on the two measured orientation parameters together with the known physical parameters. Experiments were performed to show the feasibility and effectiveness of the proposed swing angle measurement system.

  2. Measuring the ability of military aircrews to adapt to perceived stressors when undergoing centrifuge training.

    Science.gov (United States)

    Wang, Jenhung; Lin, Pei-Chun; Li, Shih-Chin

    2014-01-01

    This study assessed the ability of military aircrews to adapt to stressors when undergoing centrifuge training and determined what equipment items caused perceived stress and needed to be upgraded. We used questionnaires and the Rasch model to measure aircrew personnel's ability to adapt to centrifuge training. The measurement items were ranked by 611 military aircrew personnel. Analytical results indicated that the majority of the stress perceived by aircrew personnel resulted from the lightproof cockpit without outer reference. This study prioritized the equipment requiring updating as the lightproof cockpit design, the dim lighting of the cockpit, and the pedal design. A significant difference was found between pilot and non-pilot subjects' stress from the pedal design; and considerable association was discernible between the seat angle design and flight hours accrued. The study results provide aviators, astronauts, and air forces with reliable information as to which equipment items need to be urgently upgraded as their present physiological and psychological effects can affect the effectiveness of centrifuge training.

  3. NASA/NBS (National Aeronautics and Space Administration/National Bureau of Standards) standard reference model for telerobot control system architecture (NASREM)

    Science.gov (United States)

    Albus, James S.; Mccain, Harry G.; Lumia, Ronald

    1989-01-01

    The document describes the NASA Standard Reference Model (NASREM) Architecture for the Space Station Telerobot Control System. It defines the functional requirements and high level specifications of the control system for the NASA space Station document for the functional specification, and a guideline for the development of the control system architecture, of the 10C Flight Telerobot Servicer. The NASREM telerobot control system architecture defines a set of standard modules and interfaces which facilitates software design, development, validation, and test, and make possible the integration of telerobotics software from a wide variety of sources. Standard interfaces also provide the software hooks necessary to incrementally upgrade future Flight Telerobot Systems as new capabilities develop in computer science, robotics, and autonomous system control.

  4. Oncogenetics service and the Brazilian public health system: the experience of a reference Cancer Hospital.

    Science.gov (United States)

    Palmero, Edenir I; Galvão, Henrique C R; Fernandes, Gabriela C; Paula, André E de; Oliveira, Junea C; Souza, Cristiano P; Andrade, Carlos E; Romagnolo, Luis G C; Volc, Sahlua; C Neto, Maximiliano; Sabato, Cristina; Grasel, Rebeca; Mauad, Edmundo; Reis, Rui M; Michelli, Rodrigo A D

    2016-05-13

    The identification of families at-risk for hereditary cancer is extremely important due to the prevention potential in those families. However, the number of Brazilian genetic services providing oncogenetic care is extremely low for the continental dimension of the country and its population. Therefore, at-risk patients do not receive appropriate assistance. This report describes the creation, structure and management of a cancer genetics service in a reference center for cancer prevention and treatment, the Barretos Cancer Hospital (BCH). The Oncogenetics Department (OD) of BCH offers, free of charge, to all patients/relatives with clinical criteria, the possibility to perform i) genetic counseling, ii) preventive examinations and iii) genetic testing with the best quality standards. The OD has a multidisciplinary team and is integrated with all specialties. The genetic counseling process consists (mostly) of two visits. In 2014, 614 individuals (371 families) were seen by the OD. To date, over 800 families were referred by the OD for genetic testing. The support provided by the Oncogenetics team is crucial to identify at-risk individuals and to develop preventive and personalized behaviors for each situation, not only to the upper-middle class population, but also to the people whose only possibility is the public health system.

  5. Multidisciplinary perioperative protocol in patients undergoing acute high-risk abdominal surgery

    DEFF Research Database (Denmark)

    Tengberg, L. T.; Bay-Nielsen, M.; Bisgaard, T.

    2017-01-01

    Background: Acute high-risk abdominal (AHA) surgery carries a very high risk of morbidity and mortality and represents a massive healthcare burden. The aim of the present study was to evaluate the effect of a standardized multidisciplinary perioperative protocol in patients undergoing AHA surgery...... = 0·004). Conclusion: The introduction of a multidisciplinary perioperative protocol was associated with a significant reduction in postoperative mortality in patients undergoing AHA surgery. NCT01899885 (http://www.clinicaltrials.gov)....

  6. Behavioral Reference Model for Pervasive Healthcare Systems.

    Science.gov (United States)

    Tahmasbi, Arezoo; Adabi, Sahar; Rezaee, Ali

    2016-12-01

    The emergence of mobile healthcare systems is an important outcome of application of pervasive computing concepts for medical care purposes. These systems provide the facilities and infrastructure required for automatic and ubiquitous sharing of medical information. Healthcare systems have a dynamic structure and configuration, therefore having an architecture is essential for future development of these systems. The need for increased response rate, problem limited storage, accelerated processing and etc. the tendency toward creating a new generation of healthcare system architecture highlight the need for further focus on cloud-based solutions for transfer data and data processing challenges. Integrity and reliability of healthcare systems are of critical importance, as even the slightest error may put the patients' lives in danger; therefore acquiring a behavioral model for these systems and developing the tools required to model their behaviors are of significant importance. The high-level designs may contain some flaws, therefor the system must be fully examined for different scenarios and conditions. This paper presents a software architecture for development of healthcare systems based on pervasive computing concepts, and then models the behavior of described system. A set of solutions are then proposed to improve the design's qualitative characteristics including, availability, interoperability and performance.

  7. Will electrical cyber-physical interdependent networks undergo first-order transition under random attacks?

    Science.gov (United States)

    Ji, Xingpei; Wang, Bo; Liu, Dichen; Dong, Zhaoyang; Chen, Guo; Zhu, Zhenshan; Zhu, Xuedong; Wang, Xunting

    2016-10-01

    Whether the realistic electrical cyber-physical interdependent networks will undergo first-order transition under random failures still remains a question. To reflect the reality of Chinese electrical cyber-physical system, the "partial one-to-one correspondence" interdependent networks model is proposed and the connectivity vulnerabilities of three realistic electrical cyber-physical interdependent networks are analyzed. The simulation results show that due to the service demands of power system the topologies of power grid and its cyber network are highly inter-similar which can effectively avoid the first-order transition. By comparing the vulnerability curves between electrical cyber-physical interdependent networks and its single-layer network, we find that complex network theory is still useful in the vulnerability analysis of electrical cyber-physical interdependent networks.

  8. World Reference Base for Soil Resources

    NARCIS (Netherlands)

    Deckers, J.A.; Driessen, P.M.; Nachtergaele, F.O.; Spaargaren, O.C.

    2002-01-01

    In 1998, the International Union of Soil Sciences (IUSS) officially adopted the world reference base for soil resources (WRB) as the Union's system for soil correlation. The structure, concepts, and definitions of the WRB are strongly influenced by the FAO-UNESCO legend of the soil map of the world

  9. Errors in the SAP reference model

    NARCIS (Netherlands)

    Mendling, J.; Aalst, van der W.M.P.; Dongen, van B.F.; Verbeek, H.M.W.

    2006-01-01

    The SAP Reference Model is a set of information models that is utilized to guide the configuration of SAP systems. A big part of these models are business process models represented in the Eventdriven Process Chains (EPC) notation. These EPC models provide a easy to comprehend overview of SAP

  10. 41 CFR 105-1.109-52 - Cross-references.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Cross-references. 105-1.109-52 Section 105-1.109-52 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1...

  11. A model reference and sensitivity model-based self-learning fuzzy logic controller as a solution for control of nonlinear servo systems

    NARCIS (Netherlands)

    Kovacic, Z.; Bogdan, S.; Balenovic, M.

    1999-01-01

    In this paper, the design, simulation and experimental verification of a self-learning fuzzy logic controller (SLFLC) suitable for the control of nonlinear servo systems are described. The SLFLC contains a learning algorithm that utilizes a second-order reference model and a sensitivity model

  12. 48 CFR 552.211-72 - Reference to Specifications in Drawings.

    Science.gov (United States)

    2010-10-01

    ... Specifications in Drawings. 552.211-72 Section 552.211-72 Federal Acquisition Regulations System GENERAL SERVICES....211-72 Reference to Specifications in Drawings. As prescribed in 511.204(a), insert the following clause: References to Specifications in Drawings (FEB 1996) If military or other drawings are made a part...

  13. Enterprise Reference Library

    Science.gov (United States)

    Bickham, Grandin; Saile, Lynn; Havelka, Jacque; Fitts, Mary

    2011-01-01

    Introduction: Johnson Space Center (JSC) offers two extensive libraries that contain journals, research literature and electronic resources. Searching capabilities are available to those individuals residing onsite or through a librarian s search. Many individuals have rich collections of references, but no mechanisms to share reference libraries across researchers, projects, or directorates exist. Likewise, information regarding which references are provided to which individuals is not available, resulting in duplicate requests, redundant labor costs and associated copying fees. In addition, this tends to limit collaboration between colleagues and promotes the establishment of individual, unshared silos of information The Integrated Medical Model (IMM) team has utilized a centralized reference management tool during the development, test, and operational phases of this project. The Enterprise Reference Library project expands the capabilities developed for IMM to address the above issues and enhance collaboration across JSC. Method: After significant market analysis for a multi-user reference management tool, no available commercial tool was found to meet this need, so a software program was built around a commercial tool, Reference Manager 12 by The Thomson Corporation. A use case approach guided the requirements development phase. The premise of the design is that individuals use their own reference management software and export to SharePoint when their library is incorporated into the Enterprise Reference Library. This results in a searchable user-specific library application. An accompanying share folder will warehouse the electronic full-text articles, which allows the global user community to access full -text articles. Discussion: An enterprise reference library solution can provide a multidisciplinary collection of full text articles. This approach improves efficiency in obtaining and storing reference material while greatly reducing labor, purchasing and

  14. Neonatal and maternal outcomes comparing women undergoing two in vitro fertilization (IVF) singleton pregnancies and women undergoing one IVF twin pregnancy.

    Science.gov (United States)

    Sazonova, Antonina; Källen, Karin; Thurin-Kjellberg, Ann; Wennerholm, Ulla-Britt; Bergh, Christina

    2013-03-01

    To compare outcomes for women undergoing two in vitro fertilization (IVF) pregnancies with singletons and women undergoing one IVF twin pregnancy. The concept of single-embryo transfer in IVF has reduced the risks of both maternal and neonatal complications, but there is still a discussion of whether or not twins are a desired outcome of IVF. Registry study. Not applicable. All reported twins after IVF with double-embryo transfer (n = 1,982) and their mothers (n = 991) and all mothers (n = 921) who gave birth to two IVF singletons (n = 1,842). None. Maternal and neonatal outcomes including severe neonatal morbidity. Preterm birth, very preterm birth, low birth weight, very low birth weight, and small for gestational age were dramatically increased for IVF twins compared with two IVF singletons with the same mother, with adjusted odds ratios from 4 to 16. Significantly higher rates of respiratory complications, sepsis, and jaundice were detected among the IVF twins. Significantly higher rates of preeclampsia, preterm premature rupture of the membranes, and cesarean section were observed for IVF twin pregnancies. The neonatal and maternal outcomes were dramatically better for women undergoing two IVF singleton pregnancies compared with one IVF twin pregnancy after double-embryo transfer. These results support single-embryo transfer to minimize the risks associated with twin pregnancies. Copyright © 2013 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  15. The prevalence of iron deficiency anaemia in patients undergoing bariatric surgery.

    Science.gov (United States)

    Khanbhai, M; Dubb, S; Patel, K; Ahmed, A; Richards, T

    2015-01-01

    As bariatric surgery rates continue to climb, anaemia will become an increasing concern. We assessed the prevalence of anaemia and length of hospital stay in patients undergoing bariatric surgery. Prospective data (anaemia [haemoglobin bariatric surgery. Results from a prospective database of 1530 patients undergoing elective general surgery were used as a baseline. Fifty-seven patients (14%) were anaemic pre-operatively, of which 98% were females. Median MCV (fL) and overall median ferritin (μg/L) was lower in anaemic patients (83 vs. 86, p=0.001) and (28 vs. 61, psurgery patients, prevalence of anaemia was similar (14% vs. 16%) but absolute iron deficiency was more common in those undergoing bariatric surgery; microcytosis pbariatric surgery. In bariatric patients with anaemia there was an overall increased length of hospital stay. Copyright © 2013 Asian Oceanian Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.

  16. The cost of model reference adaptive control - Analysis, experiments, and optimization

    Science.gov (United States)

    Messer, R. S.; Haftka, R. T.; Cudney, H. H.

    1993-01-01

    In this paper the performance of Model Reference Adaptive Control (MRAC) is studied in numerical simulations and verified experimentally with the objective of understanding how differences between the plant and the reference model affect the control effort. MRAC is applied analytically and experimentally to a single degree of freedom system and analytically to a MIMO system with controlled differences between the model and the plant. It is shown that the control effort is sensitive to differences between the plant and the reference model. The effects of increased damping in the reference model are considered, and it is shown that requiring the controller to provide increased damping actually decreases the required control effort when differences between the plant and reference model exist. This result is useful because one of the first attempts to counteract the increased control effort due to differences between the plant and reference model might be to require less damping, however, this would actually increase the control effort. Optimization of weighting matrices is shown to help reduce the increase in required control effort. However, it was found that eventually the optimization resulted in a design that required an extremely high sampling rate for successful realization.

  17. Prospective, multi-institutional pain assessment of 150 women undergoing diagnostic cystoscopy.

    Science.gov (United States)

    Seklehner, Stephan; Saratlija-Novakovic, Zana; Skopek, Matthias; Fajkovic, Harun; Remzi, Mesut; Duvnjak, Mario; Resch, Irene; Hruby, Stephan; lmHÜBNER, Wilhelm; Librenjak, Davor; Breinl, Eckart; Riedl, Claus; Engelhardt, Paul F

    2016-10-01

    The aim of this study was to prospectively assess women's pain during rigid and flexible diagnostic cystoscopy and afterwards during a one-week follow-up. Prospective, multi-institutional trial analyzing numeric rating scales (NRS) of women undergoing diagnostic cystoscopy. Pain categories: no (0 points), mild (1-3), moderate (4-6) and severe pain (7-10). Assessing of pain before, during cystoscopy, and at day 1, 4 and 7 of follow-up. A total of 150 women undergoing rigid (N.=85) or flexible (N.=65) diagnostic cystoscopy were analyzed. Women undergoing flexible cystoscopy were more frequently pain-free (64.6% vs. 40%, P=0.003) and experienced mild pain less frequently (27.7% vs. 52.9% vs. P=0.002). No significant differences were noted among moderate (6.2% vs. 5.9%, P=0.95) and severe pain (1.5% vs. 1.2%, P=0.85). Patients undergoing their first (P=0.14) and repeat cystoscopy (P=0.08) had similar pain perception. In multivariate logistic regression analyses, women undergoing flexible cystoscopy had a 2.6 increased chance of being pain-free (OR=2.6, CI: 1.28-5.11, P=0.08) and their odds of experiencing mild pain were significantly lower (OR=0.34, CI: 0.17-0.71, P=0.004). The likelihood of experiencing moderate (OR=1.1, CI: 0.28- 4.4, P=0.83) or severe pain (OR=2.42, CI: 0.11-51.79, P=0.57) differed insignificantly. Rigid and flexible cystoscopies were well-tolerated by most women. However, flexible cystoscopy was associated with a higher likelihood of being pain-free and lower chances of experiencing mild pain. Patients' previous experience with cystoscopy did not influence pain perception.

  18. Anesthetic complications in dogs undergoing hepatic surgery: cholecystectomy versus non-cholecystectomy.

    Science.gov (United States)

    Burns, Brigid R; Hofmeister, Erik H; Brainard, Benjamin M

    2014-03-01

    To determine if dogs that undergo laparotomy for cholecystectomy suffer from a greater number or magnitude of perianesthetic complications, including hypotension, hypothermia, longer recovery time, and lower survival rate, than dogs that undergo laparotomy for hepatic surgery without cholecystectomy. Retrospective cohort study. One hundred and three dogs, anesthetised between January 2007 and October 2011. The variables collected from the medical record included age, weight, gender, surgical procedure, pre-operative bloodwork, American Society of Anesthesiologists (ASA) status, emergency status, total bilirubin concentration, anesthetic agents administered, body temperature nadir, final body temperature, hypotension, duration of hypotension, blood pressure nadir, intraoperative drugs, anesthesia duration, surgery duration, time to extubation, final diagnosis, days spent in the intensive care unit (ICU), total bill, survival to discharge, and survival to follow-up. No significant difference in body temperature nadir, final temperature, presence of hypotension, duration of hypotension, blood pressure nadir, the use of inotropes, or final outcome was found between dogs undergoing cholecystectomy and dogs undergoing exploratory laparotomy for other hepatic disease. Dogs that had cholecystectomy had longer anesthesia durations and longer surgery durations than dogs that did not have cholecystectomy. No significant differences existed for temperature nadir (34.8 versus 35.3°C; non-cholecystectomy versus cholecystectomy), final temperature (35.6 versus 35.9°C), time to extubation (30 versus 49 minutes), duration of hypotension (27 versus 21 minutes), or MAP nadir (56 versus 55 mmHg). Hypotension occurred in 66% and 74% and inotropes were used in 64% and 53%, for non-cholecystectomy and cholecystectomy patients, respectively. Dogs that underwent cholecystectomies did not suffer a greater number of anesthesia complications than did dogs undergoing hepatic surgery without

  19. Application of the informational reference system OZhUR to the automated processing of data from satellites of the Kosmos series

    Science.gov (United States)

    Pokras, V. M.; Yevdokimov, V. P.; Maslov, V. D.

    1978-01-01

    The structure and potential of the information reference system OZhUR designed for the automated data processing systems of scientific space vehicles (SV) is considered. The system OZhUR ensures control of the extraction phase of processing with respect to a concrete SV and the exchange of data between phases.The practical application of the system OZhUR is exemplified in the construction of a data processing system for satellites of the Cosmos series. As a result of automating the operations of exchange and control, the volume of manual preparation of data is significantly reduced, and there is no longer any need for individual logs which fix the status of data processing. The system Ozhur is included in the automated data processing system Nauka which is realized in language PL-1 in a binary one-address system one-state (BOS OS) electronic computer.

  20. Automation of Precise Time Reference Stations (PTRS)

    Science.gov (United States)

    Wheeler, P. J.

    1985-04-01

    The U.S. Naval Observatory is presently engaged in a program of automating precise time stations (PTS) and precise time reference stations (PTBS) by using a versatile mini-computer controlled data acquisition system (DAS). The data acquisition system is configured to monitor locally available PTTI signals such as LORAN-C, OMEGA, and/or the Global Positioning System. In addition, the DAS performs local standard intercomparison. Computer telephone communications provide automatic data transfer to the Naval Observatory. Subsequently, after analysis of the data, results and information can be sent back to the precise time reference station to provide automatic control of remote station timing. The DAS configuration is designed around state of the art standard industrial high reliability modules. The system integration and software are standardized but allow considerable flexibility to satisfy special local requirements such as stability measurements, performance evaluation and printing of messages and certificates. The DAS operates completely independently and may be queried or controlled at any time with a computer or terminal device (control is protected for use by authorized personnel only). Such DAS equipped PTS are operational in Hawaii, California, Texas and Florida.

  1. Multiple maxillofacial fractures in a patient undergoing orthodontic ...

    African Journals Online (AJOL)

    A multi-disciplinary team approach for the management of maxillofacial fractures in patients undergoing orthodontic treatment with fixed appliances is suggested. Orthodontic treatment with surgical involvement has been found to improve both facial aesthetics and occlusal function. Key words: Maxillofacial, trauma, ...

  2. 2002 reference document; Document de reference 2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    This 2002 reference document of the group Areva, provides information on the society. Organized in seven chapters, it presents the persons responsible for the reference document and for auditing the financial statements, information pertaining to the transaction, general information on the company and share capital, information on company operation, changes and future prospects, assets, financial position, financial performance, information on company management and executive board and supervisory board, recent developments and future prospects. (A.L.B.)

  3. A Randomized Controlled Trial Provides Evidence to Support Aromatherapy to Minimize Anxiety in Women Undergoing Breast Biopsy.

    Science.gov (United States)

    Trambert, Renee; Kowalski, Mildred Ortu; Wu, Betty; Mehta, Nimisha; Friedman, Paul

    2017-10-01

    Aromatherapy has been used to reduce anxiety in a variety of settings, but usefulness associated with breast biopsies has not been documented. This study was conducted in women undergoing image-guided breast biopsy. We explored the use of two different aromatherapy scents, compared to placebo, aimed at reducing anxiety with the intent of generating new knowledge. This was a randomized, placebo-controlled study of two different types of external aromatherapy tabs (lavender-sandalwood and orange-peppermint) compared with a matched placebo-control delivery system. Anxiety was self-reported before and after undergoing a breast biopsy using the Spielberger State Anxiety Inventory Scale. Eighty-seven women participated in this study. There was a statistically significant reduction in self-reported anxiety with the use of the lavender-sandalwood aromatherapy tab compared with the placebo group (p = .032). Aromatherapy tabs reduced anxiety during image-guided breast biopsy. The completion of the biopsy provided some relief from anxiety in all groups. The use of aromatherapy tabs offers an evidence-based nursing intervention to improve adaptation and reduce anxiety for women undergoing breast biopsy. Lavender-sandalwood aromatherapy reduced anxiety and promoted adaptation more than orange-peppermint aromatherapy or placebo. © 2017 Sigma Theta Tau International.

  4. Precision Tiltmeter as a Reference for Slope MeasuringInstruments

    Energy Technology Data Exchange (ETDEWEB)

    Kirschman, Jonathan L.; Domning, Edward E.; Morrison, Gregory Y.; Smith, Brian V.; Yashchuk, Valeriy V.

    2007-08-01

    The next generation of synchrotrons and free electron lasers require extremely high-performance x-ray optical systems for proper focusing. The necessary optics cannot be fabricated without the use of precise optical metrology instrumentation. In particular, the Long Trace Profiler (LTP) based on the pencil-beam interferometer is a valuable tool for low-spatial-frequency slope measurement with x-ray optics. The limitations of such a device are set by the amount of systematic errors and noise. A significant improvement of LTP performance was the addition of an optical reference channel, which allowed to partially account for systematic errors associated with wiggling and wobbling of the LTP carriage. However, the optical reference is affected by changing optical path length, non-homogeneous optics, and air turbulence. In the present work, we experimentally investigate the questions related to the use of a precision tiltmeter as a reference channel. Dependence of the tiltmeter performance on horizontal acceleration, temperature drift, motion regime, and kinematical scheme of the translation stage has been investigated. It is shown that at an appropriate experimental arrangement, the tiltmeter provides a slope reference for the LTP system with accuracy on the level of 0.1 {micro}rad (rms).

  5. Precision Tiltmeter as a Reference for Slope Measuring Instruments

    International Nuclear Information System (INIS)

    Kirschman, Jonathan L.; Domning, Edward E.; Morrison, Gregory Y.; Smith, Brian V.; Yashchuk, Valeriy V.

    2007-01-01

    The next generation of synchrotrons and free electron lasers require extremely high-performance x-ray optical systems for proper focusing. The necessary optics cannot be fabricated without the use of precise optical metrology instrumentation. In particular, the Long Trace Profiler (LTP) based on the pencil-beam interferometer is a valuable tool for low-spatial-frequency slope measurement with x-ray optics. The limitations of such a device are set by the amount of systematic errors and noise. A significant improvement of LTP performance was the addition of an optical reference channel, which allowed to partially account for systematic errors associated with wiggling and wobbling of the LTP carriage. However, the optical reference is affected by changing optical path length, non-homogeneous optics, and air turbulence. In the present work, we experimentally investigate the questions related to the use of a precision tiltmeter as a reference channel. Dependence of the tiltmeter performance on horizontal acceleration, temperature drift, motion regime, and kinematical scheme of the translation stage has been investigated. It is shown that at an appropriate experimental arrangement, the tiltmeter provides a slope reference for the LTP system with accuracy on the level of 0.1 (micro)rad (rms)

  6. Reference ranges for hematocrit and blood hemoglobin concentration during the neonatal period: data from a multihospital health care system.

    Science.gov (United States)

    Jopling, Jeffery; Henry, Erick; Wiedmeier, Susan E; Christensen, Robert D

    2009-02-01

    "Reference ranges" are developed when it is impossible or inappropriate to establish "normal ranges" by drawing blood on healthy normal volunteers. Reference ranges for the hematocrit and the blood hemoglobin concentration of newborn infants have previously been reported from relatively small sample sizes by using measurement methods that now are considered outmoded. We sought to develop reference ranges for hematocrit and hemoglobin during the neonatal period (28 days) by using very large sample sizes and modern hematology analyzers, accounting for gestational and postnatal age and gender. Data were assembled from a multihospital health care system after exclusion of patients with a high likelihood of an abnormal value and those who were receiving blood transfusions. During the interval from 22 to 40 weeks' gestation, the hematocrit and blood hemoglobin concentration increased approximately linearly. For every week advance in gestational age, the hematocrit increased by 0.64% and the hemoglobin concentration increased by 0.21 g/dL. No difference was seen on the basis of gender. During the 4-hour interval after birth, hematocrit/hemoglobin values of late preterm and term neonates (35-42 weeks' gestation) increased by 3.6% +/- 0.5% (mean +/- SD), those of neonates of 29 to 34 weeks' gestation remained unchanged, and those of hematocrit/hemoglobin occurred. The figures presented herein describe reference ranges for hematocrit and blood hemoglobin concentration during the neonatal period, accounting for gestational and postnatal age.

  7. A coarse-graining approach for molecular simulation that retains the dynamics of the all-atom reference system by implementing hydrodynamic interactions

    Energy Technology Data Exchange (ETDEWEB)

    Markutsya, Sergiy [Ames Laboratory, Iowa State University, Ames, Iowa 50011 (United States); Lamm, Monica H., E-mail: mhlamm@iastate.edu [Ames Laboratory, Iowa State University, Ames, Iowa 50011 (United States); Department of Chemical and Biological Engineering, Iowa State University, Ames, Iowa 50011 (United States)

    2014-11-07

    We report on a new approach for deriving coarse-grained intermolecular forces that retains the frictional contribution that is often discarded by conventional coarse-graining methods. The approach is tested for water and an aqueous glucose solution, and the results from the new implementation for coarse-grained molecular dynamics simulation show remarkable agreement with the dynamics obtained from reference all-atom simulations. The agreement between the structural properties observed in the coarse-grained and all-atom simulations is also preserved. We discuss how this approach may be applied broadly to any existing coarse-graining method where the coarse-grained models are rigorously derived from all-atom reference systems.

  8. A coarse-graining approach for molecular simulation that retains the dynamics of the all-atom reference system by implementing hydrodynamic interactions

    International Nuclear Information System (INIS)

    Markutsya, Sergiy; Lamm, Monica H.

    2014-01-01

    We report on a new approach for deriving coarse-grained intermolecular forces that retains the frictional contribution that is often discarded by conventional coarse-graining methods. The approach is tested for water and an aqueous glucose solution, and the results from the new implementation for coarse-grained molecular dynamics simulation show remarkable agreement with the dynamics obtained from reference all-atom simulations. The agreement between the structural properties observed in the coarse-grained and all-atom simulations is also preserved. We discuss how this approach may be applied broadly to any existing coarse-graining method where the coarse-grained models are rigorously derived from all-atom reference systems

  9. Metaphorical Singular Reference. The Role of Enriched Composition in Reference Resolution

    Directory of Open Access Journals (Sweden)

    Anne Bezuidenhout

    2008-08-01

    Full Text Available It is widely accepted that, in the course of interpreting a metaphorical utterance, both literal and metaphorical interpretations of the utterance are available to the interpreter, although there may be disagreement about the order in which these interpretations are accessed. I call this the dual availability assumption. I argue that it does not apply in cases of metaphorical singular reference. These are cases in which proper names, complex demonstratives or definite descriptions are used metaphorically; e.g., ‘That festering sore must go’, referring to a derelict house. We are forced to give up dual availability in these cases because a process of predicate transfer happens in the restriction clauses of such metaphorically used definite phrases (DPs, so that a denotation-less definite concept is never constructed. A process of enriched composition yields only a metaphorical referent/denotation. I compare cases of metaphorical reference both to cases of metonymic reference and to uses of epithets of the ‘That N of an N’ form. Reflection on the former is helpful in getting clear about the kind of property transfer involved in referential metaphors. Such transfer happens directly at the level of properties and is not mediated via a correspondence between objects, as is the case with metonymic reference. Reflection on epithets such as ‘that festering sore of a house’ is helpful since these are a sort of intermediate case between cases of literal and metaphorical reference. They provide support for my claim that in cases of metaphorical reference there is only a single referent (the metaphorical one. Moreover, constraints on the use of these epithets suggest that referential metaphors are similarly constrained. In particular, I argue that referential metaphors can only be used when the implicit category restriction (e.g., house in the case of the example ‘That festering sore must go’ is highly salient, and that the evaluative

  10. Material control system simulator program reference manual

    Energy Technology Data Exchange (ETDEWEB)

    Hollstien, R.B.

    1978-01-24

    A description is presented of a Material Control System Simulator (MCSS) program for determination of material accounting uncertainty and system response to particular adversary action sequences that constitute plausible material diversion attempts. The program is intended for use in situations where randomness, uncertainty, or interaction of adversary actions and material control system components make it difficult to assess safeguards effectiveness against particular material diversion attempts. Although MCSS may be used independently in the design or analysis of material handling and processing systems, it has been tailored toward the determination of material accountability and the response of material control systems to adversary action sequences.

  11. Material control system simulator program reference manual

    International Nuclear Information System (INIS)

    Hollstien, R.B.

    1978-01-01

    A description is presented of a Material Control System Simulator (MCSS) program for determination of material accounting uncertainty and system response to particular adversary action sequences that constitute plausible material diversion attempts. The program is intended for use in situations where randomness, uncertainty, or interaction of adversary actions and material control system components make it difficult to assess safeguards effectiveness against particular material diversion attempts. Although MCSS may be used independently in the design or analysis of material handling and processing systems, it has been tailored toward the determination of material accountability and the response of material control systems to adversary action sequences

  12. Fertility counseling and preservation practices in youth with lupus and vasculitis undergoing gonadotoxic therapy.

    Science.gov (United States)

    Nahata, Leena; Sivaraman, Vidya; Quinn, Gwendolyn P

    2016-11-01

    To assess fertility counseling and preservation practices among children, adolescents, and young adults with rheumatic diseases undergoing cyclophosphamide (CTX) treatment. Retrospective chart review (2006-2016). Academic pediatric center. Male and female patients with systemic lupus erythematosus, Wegener's granulomatosis/granulomatosis with polyangiitis, or other vaculitides, receiving CTX treatment. None. Documentation of fertility counseling and fertility preservation. A total of 58 subjects met the inclusion criteria; 5 were excluded due to incomplete records, thus N = 53. Of these 75% were female (N = 40). Median age was 14 years at diagnosis and 15 years at first CTX treatment. A total of 51% of subjects (69% of males and 45% of females) had no documentation about potential fertility loss before CTX treatment. Among females where fertility counseling was documented, the only fertility preservation option discussed was leuprolide acetate (LA), which was pursued in all of these cases. Of 13 males (77% postpubertal), 3 were offered sperm banking, of whom 2 declined and the other attempted after treatment began and was azoospermic. Of 53 patients, 1 was referred to a fertility specialist. Mean cumulative CTX dose was 9.2 g in males and 8 g in females. Based on these findings, increasing awareness about infertility risk, fertility preservation options, and referral to fertility specialists is needed among pediatric rheumatologists. Prospective studies are needed to assess fertility outcomes in this patient population (including effectiveness of LA with regard to pregnancy rates [PRs]), as well as barriers/facilitators to fertility counseling and fertility preservation. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  13. Study of dosimetric quantities applied to patient undergoing routine chest examinations by computed tomography

    International Nuclear Information System (INIS)

    Gonzaga, Natalia Barbosa

    2012-01-01

    The radiological protection system has established a standard to protect persons against the harmful effects caused by ionizing radiation that is based on the justification, optimization and dose limitation principles. The increasing use of radiation in medicine and the related risks have stressed the discussion on patient radiation protection. The computed tomography (CT) is the diagnostic radiology technique that most contributes to patient doses and it requires optimization efforts. Diagnostic reference levels (DRL) has been established in many countries in terms of CT dosimetric quantities; in Brazil, the DRLs are still under investigation since the culture of patient protection is not very strong yet. The objective of this work was to investigate the dosimetric and protection quantities related to patients undergoing CT routine chest examinations. The ImPACT CT, CT Expo and ImpactDose softwares were used for calculations of the weight and volumetric air-kerma indexes (CW and CVOL), the air kerma - length product (P K,L ), organ equivalent dose (H T ) and the effective dose (E) for CT routine chest protocols in 19 tomographs in Belo Horizonte city. The CT Expo was selected to be validated against experimental measurements in three hospitals with thermoluminescent dosimeters and CT pencil ionization chamber in anthropomorphic and standard CT body phantoms. Experimental and calculated results indicated differences up to 97% for H T and E and acceptable agreement for C W ,C VOL and P K,L . All data from 19 tomographs showed that local DRLs for CT routine chest examinations may be chosen smaller than DRLs adopted in other countries; this would contribute to increase the radiological protection of patients. (author)

  14. Overall properties of the Gaia DR1 reference frame

    Science.gov (United States)

    Liu, N.; Zhu, Z.; Liu, J.-C.; Ding, C.-Y.

    2017-03-01

    Aims: The first Gaia data release (Gaia DR1) provides 2191 ICRF2 sources with their positions in the auxiliary quasar solution and five astrometric parameters - positions, parallaxes, and proper motions - for stars in common between the Tycho-2 catalogue and Gaia in the joint Tycho-Gaia astrometric solution (TGAS). We aim to analyze the overall properties of Gaia DR1 reference frame. Methods: We compare quasar positions of the auxiliary quasar solution with ICRF2 sources using different samples and evaluate the influence on the Gaia DR1 reference frame owing to the Galactic aberration effect over the J2000.0-J2015.0 period. Then we estimate the global rotation between TGAS with Tycho-2 proper motion systems to investigate the property of the Gaia DR1 reference frame. Finally, the Galactic kinematics analysis using the K-M giant proper motions is performed to understand the property of Gaia DR1 reference frame. Results: The positional comparison between the auxiliary quasar solution and ICRF2 shows negligible orientation and validates the declination bias of -0.1mas in Gaia quasar positions with respect to ICRF2. Galactic aberration effect is thought to cause an offset 0.01mas of the Z axis direction of Gaia DR1 reference frame. The global rotation between TGAS and Tycho-2 proper motion systems, obtained by different samples, shows a much smaller value than the claimed value 0.24mas yr-1. For the Galactic kinematics analysis of the TGAS K-M giants, we find possible non-zero Galactic rotation components beyond the classical Oort constants: the rigid part ωYG = -0.38±0.15mas yr-1 and the differential part ω^primeYG = -0.29±0.19mas yr-1 around the YG axis of Galactic coordinates, which indicates possible residual rotation in Gaia DR1 reference frame or problems in the current Galactic kinematical model. Conclusions: The Gaia DR1 reference frame is well aligned to ICRF2, and the possible influence of the Galactic aberration effect should be taken into consideration

  15. Context controls access to working and reference memory in the pigeon (Columba livia).

    Science.gov (United States)

    Roberts, William A; Macpherson, Krista; Strang, Caroline

    2016-01-01

    The interaction between working and reference memory systems was examined under conditions in which salient contextual cues were presented during memory retrieval. Ambient colored lights (red or green) bathed the operant chamber during the presentation of comparison stimuli in delayed matching-to-sample training (working memory) and during the presentation of the comparison stimuli as S+ and S- cues in discrimination training (reference memory). Strong competition between memory systems appeared when the same contextual cue appeared during working and reference memory training. When different contextual cues were used, however, working memory was completely protected from reference memory interference. © 2016 Society for the Experimental Analysis of Behavior.

  16. Platelet activation in outpatients undergoing esophagogastroduodenoscopy

    International Nuclear Information System (INIS)

    Sagripanti, A.; Polloni, A.; Materazzi, F.; Ferdeghini, M.; Pinori, E.; Bianchi, R.

    1989-01-01

    To evaluate the influence of emotional stress on platelet function mesured by radioimmunoassay in plasma two platelet factor 4, in a series of outpatients undergoing esophagogastroduodenoscopy for upper digestive complaints has been measured. The plasma levels of β-thromboglobulin and platelet factor 4, determined just before the instrumental examination, were significantly more elevated as compared to basal values, checked a week later. These results provide evidence of enhanced in vivo platelet release reaction during emotional stress

  17. The Computerized Reference Department: Buying the Future.

    Science.gov (United States)

    Kriz, Harry M.; Kok, Victoria T.

    1985-01-01

    Basis for systematic computerization of academic research library's reference, collection development, and collection management functions emphasizes productivity enhancement for librarians and support staff. Use of microcomputer and university's mainframe computer to develop applications of database management systems, electronic spreadsheets,…

  18. Fit Gap Analysis – The Role of Business Process Reference Models

    Directory of Open Access Journals (Sweden)

    Dejan Pajk

    2013-12-01

    Full Text Available Enterprise resource planning (ERP systems support solutions for standard business processes such as financial, sales, procurement and warehouse. In order to improve the understandability and efficiency of their implementation, ERP vendors have introduced reference models that describe the processes and underlying structure of an ERP system. To select and successfully implement an ERP system, the capabilities of that system have to be compared with a company’s business needs. Based on a comparison, all of the fits and gaps must be identified and further analysed. This step usually forms part of ERP implementation methodologies and is called fit gap analysis. The paper theoretically overviews methods for applying reference models and describes fit gap analysis processes in detail. The paper’s first contribution is its presentation of a fit gap analysis using standard business process modelling notation. The second contribution is the demonstration of a process-based comparison approach between a supply chain process and an ERP system process reference model. In addition to its theoretical contributions, the results can also be practically applied to projects involving the selection and implementation of ERP systems.

  19. Thick-film voltammetric pH-sensors with internal indicator and reference species

    DEFF Research Database (Denmark)

    Musa, Arnaud Emmanuel; Alonso-Lomillo, María Asunción; del Campo, Francisco Javier

    2012-01-01

    , low cost and ease of fabrication. More importantly, as opposed to conventional voltammetric systems where the height of the voltammetric peaks is taken into account to quantify the amount of a species of interest, here, the difference between the peak potential of the indicator species and the peak...... potential of the reference species is used. Thus, this measurement principle makes the electrochemical system presented here less dependent on the potential of the reference electrode (RE), as is often the case in other electrochemical systems. The developed system displays very promising performances...

  20. Reference interval determination of hemoglobin fractions in umbilical cord and placental blood by capillary electrophoresis.

    Science.gov (United States)

    Bó, Suzane Dal; de Oliveira Lemos, Fabiane Kreutz; Pedrazzani, Fabiane Spagnol; Cagliari, Cláudia Rosa; Scotti, Luciana

    2016-04-01

    Umbilical cord and placental blood (UCPB) is a rich source of hematopoietic stem cells widely used to treat diseases that did not have effective treatments until recently. Umbilical cord and placental blood banks (UCPBBs) are needed to be created to store UCPB. UCPB is collected immediately after birth, processed, and frozen until infusion. Detection of abnormal hemoglobins is one of UCPB screening tests available. The objective of the present study was to determine the reference interval for HbA, HbF, and HbA2 in UCPB using capillary electrophoresis. Methods: Observational retrospective study of UCPB samples undergoing hemoglobin electrophoresis was performed between April 2012 and May 2013. We analyzed 273 UCPB samples. All cords met the criteria of BrasilCORD. We found 19.9% (10.5–36.7%) for HbA, 80.1% (62.7–89.4%) for HbF, and 0.1% (0.0–0.6%) for HbA2. Data were expressed as median (P2.5–P97.5). Establishing specific reference intervals is the best option for most tests because such ranges reflect the status of the population in which the tests will be applied. The use of appropriate reference intervals ensures that clinical labs provide reliable information, thus enabling clinicians to correctly interpret results and choose the best approach for the target population.

  1. Uranium reference materials

    International Nuclear Information System (INIS)

    Donivan, S.; Chessmore, R.

    1987-07-01

    The Technical Measurements Center has prepared uranium mill tailings reference materials for use by remedial action contractors and cognizant federal and state agencies. Four materials were prepared with varying concentrations of radionuclides, using three tailings materials and a river-bottom soil diluent. All materials were ground, dried, and blended thoroughly to ensure homogeneity. The analyses on which the recommended values for nuclides in the reference materials are based were performed, using independent methods, by the UNC Geotech (UNC) Chemistry Laboratory, Grand Junction, Colorado, and by C.W. Sill (Sill), Idaho National Engineering Laboratory, Idaho Falls, Idaho. Several statistical tests were performed on the analytical data to characterize the reference materials. Results of these tests reveal that the four reference materials are homogeneous and that no large systematic bias exists between the analytical methods used by Sill and those used by TMC. The average values for radionuclides of the two data sets, representing an unbiased estimate, were used as the recommended values for concentrations of nuclides in the reference materials. The recommended concentrations of radionuclides in the four reference materials are provided. Use of these reference materials will aid in providing uniform standardization among measurements made by remedial action contractors. 11 refs., 9 tabs

  2. Robust stator resistance identification of an IM drive using model reference adaptive system

    International Nuclear Information System (INIS)

    Madadi Kojabadi, Hossein; Abarzadeh, Mostafa; Aghaei Farouji, Said

    2013-01-01

    Highlights: ► We estimate the stator resistance and rotor speed of the IM. ► We proposed a new quantity to estimate the speed and stator resistance of IM. ► The proposed algorithm is robust to rotor resistance variations. ► We estimate the IM speed and stator resistance simultaneously to avoid speed error. - Abstract: Model reference adaptive system (MRAS) based robust stator resistance estimator for sensorless induction motor (IM) drive is proposed. The MRAS is formed with a semi-active power quantity. The proposed identification method can be achieved with on-line tuning of the stator resistance with robustness against rotor resistance variations. Stable and efficient estimation of IM speed at low region will be guaranteed by simultaneous identification of IM speed and stator resistance. The stability of proposed stator resistance estimator is checked through Popov’s hyperstability theorem. Simulation and experimental results are given to highlight the feasibility, the simplicity, and the robustness of the proposed method.

  3. Three-Dimensional Imaging by Self-Reference Single-Channel Digital Incoherent Holography

    Science.gov (United States)

    Rosen, Joseph; Kelner, Roy

    2016-01-01

    Digital holography offers a reliable and fast method to image a three-dimensional scene from a single perspective. This article reviews recent developments of self-reference single-channel incoherent hologram recorders. Hologram recorders in which both interfering beams, commonly referred to as the signal and the reference beams, originate from the same observed objects are considered as self-reference systems. Moreover, the hologram recorders reviewed herein are configured in a setup of a single channel interferometer. This unique configuration is achieved through the use of one or more spatial light modulators. PMID:28757811

  4. Children with chronic renal disease undergoing dialysis or conservative treatment--differences in structural and functional echocardiographic parameters.

    Science.gov (United States)

    Scavarda, Valeska Tavares; Pinheiro, Aurelio Carvalho; Costa, Symône Damasceno; de Andrade, Zélia Maria; Carvalhaes, João Tomás de Abreu; Campos, Orlando; Carvalho, Antonio Carlos; Moises, Valdir Ambrosio

    2014-10-01

    Cardiac disease frequently occurs in children with chronic kidney disease (CKD) undergoing dialysis (DI), but it is not well studied in patients undergoing conservative treatment (CT). The aim of our study was to use echocardiography to analyze and compare the cardiac involvement of children with CKD undergoing DI or CT. Seventy-one children with CKD were included; 41 undergoing DI and 30 undergoing CT. There were 33 controls. Measurements of arterial pressure and structural and functional echocardiographic variables were obtained; the children were followed up for 18 months. Tests of comparison and multiple regression were used; significant if P < 0.05. Arterial hypertension (AH) was present in 37 of 71 (52%) children with CKD: 27 (65.8%) in DI and 10 (33.3%) in CT (X2 = 8.7; P = 0.003). An abnormal left ventricular geometric pattern was present in 37/41 (90.3%) undergoing DI, 33 had left ventricular hypertrophy (LVH), and in 14/30 (46.7%) undergoing CT, 5 had LVH. Ejection fraction was normal in all groups; diastolic function alteration (DFA) occurred in 28/41 (68.3%) children on DI and in 10/30 (33.3%) on CT (X2 = 9.2; P = 0.002). For children with CKD, DI (P = 0.002) and hypertension (P = 0.04) were associated with LVH; among those on DI, only AH was associated with LVH (P = 0.02). During the follow-up, 18 (43.9%) children undergoing DI had at least one cardiovascular event. Children with CKD undergoing CT had less cardiac involvement than those undergoing DI. LVH was associated with DI and AH in all children with CKD and with AH in those on DI.

  5. Reference Assessment

    Science.gov (United States)

    Bivens-Tatum, Wayne

    2006-01-01

    This article presents interesting articles that explore several different areas of reference assessment, including practical case studies and theoretical articles that address a range of issues such as librarian behavior, patron satisfaction, virtual reference, or evaluation design. They include: (1) "Evaluating the Quality of a Chat Service"…

  6. Micro-arcsecond Celestial Reference Frames: definition and realization — Impact of the recent IAU Resolutions

    International Nuclear Information System (INIS)

    Capitaine, Nicole

    2012-01-01

    The adoption of the International Celestial Reference System (ICRS), based on Very Long Baseline Interferometry (VLBI) observations of extragalactic radiosources by the International Astronomical Union (IAU) since 1998 January 1, opened a new era for astronomy. The ICRS and the corresponding frame, the International Celestial Reference Frame (ICRF), replaced the Fundamental Catalog (FK5) based on positions and proper motions of bright stars, with the Hipparcos catalog being adopted as the primary realization of the ICRS in optical wavelengths. According to its definition, the ICRS is such that the barycentric directions of distant extragalactic objects show no global rotation with respect to these objects; this provides a quasi-inertial reference for measuring the positions and angular motions of the celestial objects. Other resolutions on reference systems were passed by the IAU in 2000 and 2006 and endorsed by the International Union of Geodesy and Geophysics (IUGG) in 2003 and 2007, respectively. These especially concern the definition and realization of the astronomical reference systems in the framework of general relativity and transformations between them. First, the IAU 2000 resolutions refined the concepts and definition of the astronomical reference systems and parameters for Earth's rotation, and adopted the IAU 2000 precession-nutation. Then, the IAU 2006 resolutions adopted a new precession model that is consistent with dynamical theories; they also addressed definition, terminology or orientation issues relative to reference systems and time scales that needed to be specified after the adoption of the IAU 2000 resolutions. An additional IUGG 2007 resolution defined the International Terrestrial Reference System (ITRS) so that it strictly complies with the IAU recommendations. Finally, the IAU 2009 resolutions adopted a new system of astronomical constants and an improved realization of the ICRF. These fundamental changes have led to significant

  7. Performance of PROMIS for Healthy Patients Undergoing Meniscal Surgery.

    Science.gov (United States)

    Hancock, Kyle J; Glass, Natalie; Anthony, Chris A; Hettrich, Carolyn M; Albright, John; Amendola, Annunziato; Wolf, Brian R; Bollier, Matthew

    2017-06-07

    The Patient-Reported Outcomes Measurement Information System (PROMIS) was developed as an extensive question bank with multiple health domains that could be utilized for computerized adaptive testing (CAT). In the present study, we investigated the use of the PROMIS Physical Function CAT (PROMIS PF CAT) in an otherwise healthy population scheduled to undergo surgery for meniscal injury with the hypotheses that (1) the PROMIS PF CAT would correlate strongly with patient-reported outcome instruments that measure physical function and would not correlate strongly with those that measure other health domains, (2) there would be no ceiling effects, and (3) the test burden would be significantly less than that of the traditional measures. Patients scheduled to undergo meniscal surgery completed the PROMIS PF CAT, Knee injury and Osteoarthritis Outcome Score (KOOS), Marx Knee Activity Rating Scale, Short Form-36 (SF-36), and EuroQol-5 Dimension (EQ-5D) questionnaires. Correlations were defined as high (≥0.7), high-moderate (0.61 to 0.69), moderate (0.4 to 0.6), moderate-weak (0.31 to 0.39), or weak (≤0.3). If ≥15% respondents to a patient-reported outcome measure obtained the highest or lowest possible score, the instrument was determined to have a significant ceiling or floor effect. A total of 107 participants were analyzed. The PROMIS PF CAT had a high correlation with the SF-36 Physical Functioning (PF) (r = 0.82, p ceiling effects, with 0% of the participants achieving the lowest and highest score, respectively. The PROMIS PF CAT correlates strongly with currently used patient-reported outcome measures of physical function and demonstrates no ceiling effects for patients with meniscal injury requiring surgery. It may be a reasonable alternative to more burdensome patient-reported outcome measures.

  8. Consistent realization of Celestial and Terrestrial Reference Frames

    Science.gov (United States)

    Kwak, Younghee; Bloßfeld, Mathis; Schmid, Ralf; Angermann, Detlef; Gerstl, Michael; Seitz, Manuela

    2018-03-01

    The Celestial Reference System (CRS) is currently realized only by Very Long Baseline Interferometry (VLBI) because it is the space geodetic technique that enables observations in that frame. In contrast, the Terrestrial Reference System (TRS) is realized by means of the combination of four space geodetic techniques: Global Navigation Satellite System (GNSS), VLBI, Satellite Laser Ranging (SLR), and Doppler Orbitography and Radiopositioning Integrated by Satellite. The Earth orientation parameters (EOP) are the link between the two types of systems, CRS and TRS. The EOP series of the International Earth Rotation and Reference Systems Service were combined of specifically selected series from various analysis centers. Other EOP series were generated by a simultaneous estimation together with the TRF while the CRF was fixed. Those computation approaches entail inherent inconsistencies between TRF, EOP, and CRF, also because the input data sets are different. A combined normal equation (NEQ) system, which consists of all the parameters, i.e., TRF, EOP, and CRF, would overcome such an inconsistency. In this paper, we simultaneously estimate TRF, EOP, and CRF from an inter-technique combined NEQ using the latest GNSS, VLBI, and SLR data (2005-2015). The results show that the selection of local ties is most critical to the TRF. The combination of pole coordinates is beneficial for the CRF, whereas the combination of Δ UT1 results in clear rotations of the estimated CRF. However, the standard deviations of the EOP and the CRF improve by the inter-technique combination which indicates the benefits of a common estimation of all parameters. It became evident that the common determination of TRF, EOP, and CRF systematically influences future ICRF computations at the level of several μas. Moreover, the CRF is influenced by up to 50 μas if the station coordinates and EOP are dominated by the satellite techniques.

  9. Experiense with remineraling means in patients undergoing orthodontic treatment

    Directory of Open Access Journals (Sweden)

    Stepanova Ye.A.

    2011-03-01

    Full Text Available In patients undergoing orthodontic treatment using bracket-technology a high risk of caries development. The algorithm of preventive interventions for the prevention of hair demineralization of enamel of the teeth

  10. Severity of coronary artery disease in obese patients undergoing coronary angiography

    International Nuclear Information System (INIS)

    Javed, A.; Ali, J.; Kayani, A.M.

    2012-01-01

    Objective: To assess the relationship of severity of coronary artery disease with obesity in patients undergoing coronary angiography. Design: Cross sectional study. Place and Duration of Study: Armed Forces Institute of Cardiology - National Institute of Heart Diseases (AFIC-NIHD), 1st February 2010 to 31st August 2010 Patients and Methods: The study population included 468 patients undergoing coronary angiography. Obesity was classified according to the BMI using the National Institutes of Health (NIH) criteria as normal (BMI 21-24 kg/m2), overweight (BMI 25-29 kg/m2), obesity class I (BMI 30-34 kg/m2), obesity class II (BMI 35 to 39 kg/m2 and obesity class III (BMI 40 or above kg/m2). Coronary angiography data were obtained from the Siemens Queries software system, which maintains the database including detailed angiographic findings of all patients at this institution. Significant lesions were defined as those with >70% diameter narrowing of coronary arteries (>50% for the left main coronary artery). We attempted to quantify the 'severity of CAD' by ascertaining the prevalence of High-Risk Coronary Anatomy (HRCA). Results: Insignificant difference was observed in traditional risk factors i.e. age, diabetes mellitus and smoking except hypertension and gender. Statistically significantly low prevalence of HRCA was encountered in the obese group (57.7%) as compared to normal/overweight group (75.8%) (p < 0.05). Conclusion: We conclude that obesity is associated with less severe coronary artery disease. (author)

  11. Postoperative atrial fibrillation in patients on statins undergoing ...

    African Journals Online (AJOL)

    Introduction: The efficacy of perioperative statin therapy in decreasing postoperative morbidity in patients undergoing valve replacements and repairs is unknown. The aim of our study was to determine whether or not the literature supports the hypothesis that statins decrease postoperative atrial fibrillation (AF), and hence ...

  12. Measuring pain in patients undergoing hemodialysis: a review of pain assessment tools

    OpenAIRE

    Upadhyay, Chandani; Cameron, Karen; Murphy, Laura; Battistella, Marisa

    2014-01-01

    Background Patients undergoing hemodialysis frequently report pain with multifactorial causes, not limited to that experienced directly from hemodialysis treatment. Their pain may be nociceptive, neuropathic, somatic or visceral in nature. Despite this, pain in this population remains under-recognized and under-treated. Although several tools have been used to measure pain in patients undergoing hemodialysis as reported in the literature, none of them have been validated specifically in this ...

  13. Mycoplasma in urine and blood following catheterisation of patients undergoing vascular surgery

    DEFF Research Database (Denmark)

    Levi, N; Eiberg, J; Skov Jensen, J

    1997-01-01

    The purpose of this investigation was to determine if mycoplasmas enter the bloodstream after urinary tract catheterisation in patients undergoing vascular surgery in order to evaluate the efficiency of the routine prophylactic antibiotic treatment.......The purpose of this investigation was to determine if mycoplasmas enter the bloodstream after urinary tract catheterisation in patients undergoing vascular surgery in order to evaluate the efficiency of the routine prophylactic antibiotic treatment....

  14. Radon-daughter chamber instrumentation system reference manual

    International Nuclear Information System (INIS)

    Showalter, R.; Johnson, L.

    1985-01-01

    The radon-daughter chamber instrumentation system collects environmental data from the radon-daughter chamber. These data are then recorded on a Tandberg system tape cartridge and transmitted to the HP-1000 computer for processing. Generators which inject radon and condensation nuclei into the chamber are also included with the instrumentation system

  15. Multi-media communication system: Upper layers in the OSI reference model

    NARCIS (Netherlands)

    Zafirovic-Vukotic, M.; Niemegeers, I.G.M.M.

    1992-01-01

    The structuring, services, and major protocol functions that are required in the upper layers of the OSI reference model in order to support end-to-end multimedia communication, assuming a simple transport service, are examined. It is assumed that variable-bit-rate (VBR) coding techniques will be

  16. Electrothermal frequency references in standard CMOS

    CERN Document Server

    Kashmiri, S Mahdi

    2013-01-01

    This book describes an alternative method of accurate on-chip frequency generation in standard CMOS IC processes. This method exploits the thermal-diffusivity of silicon, the rate at which heat diffuses through a silicon substrate.  This is the first book describing thermal-diffusivity-based frequency references, including the complete theoretical methodology supported by practical realizations that prove the feasibility of the method.  Coverage also includes several circuit and system-level solutions for the analog electronic circuit design challenges faced.   ·         Surveys the state-of-the-art in all-silicon frequency references; ·         Examines the thermal properties of silicon as a solution for the challenge of on-chip accurate frequency generation; ·         Uses simplified modeling approaches that allow an electronics engineer easily to simulate the electrothermal elements; ·         Follows a top-down methodology in circuit design, in which system-level des...

  17. Risks of cardiovascular adverse events and death in patients with previous stroke undergoing emergency noncardiac, nonintracranial surgery

    DEFF Research Database (Denmark)

    Christiansen, Mia N.; Andersson, Charlotte; Gislason, Gunnar H.

    2017-01-01

    Background: The outcomes of emergent noncardiac, nonintracranial surgery in patients with previous stroke remain unknown. Methods: All emergency surgeries performed in Denmark (2005 to 2011) were analyzed according to time elapsed between previous ischemic stroke and surgery. The risks of 30-day...... mortality and major adverse cardiovascular events were estimated as odds ratios (ORs) and 95% CIs using adjusted logistic regression models in a priori defined groups (reference was no previous stroke). In patients undergoing surgery immediately (within 1 to 3 days) or early after stroke (within 4 to 14...... and general anesthesia less frequent in patients with previous stroke (all P Risks of major adverse cardiovascular events and mortality were high for patients with stroke less than 3 months (20.7 and 16.4% events; OR = 4.71 [95% CI, 4.18 to 5.32] and 1.65 [95% CI, 1.45 to 1.88]), and remained...

  18. Small-bowel neoplasms in patients undergoing video capsule endoscopy

    DEFF Research Database (Denmark)

    Rondonotti, E; Pennazio, M; Toth, E

    2008-01-01

    BACKGROUND AND STUDY AIM: Small-bowel tumors account for 1% - 3% of all gastrointestinal neoplasms. Recent studies with video capsule endoscopy (VCE) suggest that the frequency of these tumors may be substantially higher than previously reported. The aim of the study was to evaluate the frequency......, clinical presentation, diagnostic/therapeutic work-up, and endoscopic appearance of small-bowel tumors in a large population of patients undergoing VCE. PATIENTS AND METHODS: Identification by a questionnaire of patients with VCE findings suggesting small-bowel tumors and histological confirmation...... of the neoplasm seen in 29 centers of 10 European Countries. RESULTS: Of 5129 patients undergoing VCE, 124 (2.4%) had small-bowel tumors (112 primary, 12 metastatic). Among these patients, indications for VCE were: obscure gastrointestinal bleeding (108 patients), abdominal pain (9), search for primary neoplasm...

  19. Reference Mission Version 3.0 Addendum to the Human Exploration of Mars: The Reference Mission of the NASA Mars Exploration Study Team. Addendum; 3.0

    Science.gov (United States)

    Drake, Bret G. (Editor)

    1998-01-01

    This Addendum to the Mars Reference Mission was developed as a companion document to the NASA Special Publication 6107, "Human Exploration of Mars: The Reference Mission of the NASA Mars Exploration Study Team." It summarizes changes and updates to the Mars Reference Missions that were developed by the Exploration Office since the final draft of SP 6107 was printed in early 1999. The Reference Mission is a tool used by the exploration community to compare and evaluate approaches to mission and system concepts that could be used for human missions to Mars. It is intended to identify and clarify system drivers, significant sources of cost, performance, risk, and schedule variation. Several alternative scenarios, employing different technical approaches to solving mission and technology challenges, are discussed in this Addendum. Comparing alternative approaches provides the basis for continual improvement to technology investment plan and a general understanding of future human missions to Mars. The Addendum represents a snapshot of work in progress in support of planning for future human exploration missions through May 1998.

  20. Development of the regional EPR and PACS sharing system on the infrastructure of cloud computing technology controlled by patient identifier cross reference manager.

    Science.gov (United States)

    Kondoh, Hiroshi; Teramoto, Kei; Kawai, Tatsurou; Mochida, Maki; Nishimura, Motohiro

    2013-01-01

    A Newly developed Oshidori-Net2, providing medical professionals with remote access to electronic patient record systems (EPR) and PACSs of four hospitals, of different venders, using cloud computing technology and patient identifier cross reference manager. The operation was started from April 2012. The patients moved to other hospital were applied. Objective is to show the merit and demerit of the new system.

  1. Valores de referência para carboxiemoglobina Reference values for carboxyhemoglobin

    Directory of Open Access Journals (Sweden)

    Maria Elisa P. B. de Siqueira

    1997-12-01

    Full Text Available INTRODUÇÃO: Os valores de referência de indicadores biológicos são utilizados como parâmetros para interpretação de resultados de valores obtidos em indivíduos expostos ocupacionalmente aos agentes químicos. O Grupo Brasileiro para Estabelecimento dos Valores de Referência tem se dedicado a estas determinações objetivando estabelecer valores de referência para os diferentes bioindicadores em diversas regiões do País. Determinaram-se os valores de referência para a carboxiemoglobina (COHb no Sul de Minas Gerais. MATERIAL E MÉTODO: A COHb foi analisada pelo método espectrofométrico, otimizado no laboratório de análises toxicológicas. Em todas as amostras também foram realizadas análises de alguns parâmetros bioquímicos e hematológicos para atestar o estado de saúde da população, constituída de 200 voluntários não-fumantes e não-expostos, por motivo profissional, ao monóxido de carbono. Cada indivíduo respondeu um questionário para levantamento de dados relevantes à interpretação dos resultados. Os valores de referência foram expressos em termos da média ± desvio-padrão, intervalo de confiança 95% e valor de referência superior. A distribuição estatística dos resultados obtidos foi realizada para possibilitar sua comparação com grupos de trabalhadores, preferentemente à avaliação individual. RESULTADOS E CONCLUSÕES: O valor médio ± desvio-padrão para a carboxiemoglobina foi de 1,0 % ± 0,75; o intervalo de confiança 95%, entre 0,9 e 1,1 % e o valor de referência superior, de 2,5%. Através do teste t de Student (p INTRODUCTION: The reference values (RV of biological indicators are used in the interpretation of the results of such indicators in individuals occupationally exposed to chemical agents. The Brazilian Group for the Establishment of Reference Values has worked on these definitions for the purpose of establishing RVs for several bioindicators in various regions of the country. In

  2. Patients undergoing elective coronary artery bypass grafting exhibit poor pre-operative intakes of fruit, vegetables, dietary fibre, fish and vitamin D

    NARCIS (Netherlands)

    Ruiz-Nunez, B.; van den Hurk, G. H. A. M.; de Vries, J. H. M.; Mariani, M. A.; de Jongste, M. J. L.; Dijck-Brouwer, D. A. J.; Muskiet, F. A. J.

    2015-01-01

    CHD may ensue from chronic systemic low-grade inflammation. Diet is a modifiable risk factor for both, and its optimisation may reduce post-operative mortality, atrial fibrillation and cognitive decline. In the present study, we investigated the usual dietary intakes of patients undergoing elective

  3. Patients undergoing elective coronary artery bypass grafting exhibit poor pre-operative intakes of fruit, vegetables, dietary fibre, fish and vtiman D

    NARCIS (Netherlands)

    Ruiz-Nunez, B.; Hurk, van den Y.A.C.; Vries, de J.H.M.

    2015-01-01

    CHD may ensue from chronic systemic low-grade inflammation. Diet is a modifiable risk factor for both, and its optimisation may reduce post-operative mortality, atrial fibrillation and cognitive decline. In the present study, we investigated the usual dietary intakes of patients undergoing elective

  4. Operators Manual and Technical Reference for the Z-Beamlet Phase Modulation Failsafe System: Version 1.

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, Darrell J.

    2014-09-01

    The need for pulse energies exceeding 4 kJ and pulse lengths [?] 2 ns in Sandia's Z-Beamlet laser (ZBL) requires that the single-frequency spectrum of its fiber-laser master oscillator be converted to a phase modulated spectrum with a modulation in dex [?] 5. Because accidental injection of single-frequency light into ZBL could result i n damage to optical materials from transverse stimulated Brillouin scattering, the presence of phase modulated (PM) light must be monitored by a reliable failsafe system that can stop a las er shot within of a few 10's of ns following a failure of the PM system. This requirement is met by combining optical heterodyne detection with high-speed electronics to indicate the pres ence or absence of phase modulated light. The transition time for the failsafe signal resultin g from a sudden failure using this technique is approximately 35 ns. This is sufficiently short to safely stop a single-frequency laser pulse from leaving ZBL's regenerative amplifier with a n approximately 35 ns margin of safety. This manual and technical reference contains detai led instructions for daily use of the PM failsafe system and provides enough additional informat ion for its maintenance and repair.

  5. [The health of adults undergoing an eviction process].

    Science.gov (United States)

    Bolívar Muñoz, Julia; Bernal Solano, Mariola; Mateo Rodríguez, Inmaculada; Daponte Codina, Antonio; Escudero Espinosa, Cecilia; Sánchez Cantalejo, Carmen; González Usera, Isis; Robles Ortega, Humbelina; Mata Martín, José Luis; Fernández Santaella, M Carmen; Vila Castellar, Jaime

    2016-01-01

    To analyze perceived health status and other health-related indicators in the adult population in Granada (Spain) undergoing an eviction process from their homes, whether rented or owned, in comparison with health indicators in the general adult population in Andalusia. A cross-sectional survey was administered by trained staff. The survey included instruments from the Andalusian Health Survey 2011 for measuring variables related to physical and mental health, as well as health-related habits. We compared the results with those obtained from the Andalusian general population through the Andalusian Health Survey. A bivariate analysis using the χ2 test and a multivariate logistic regression analysis were conducted. We obtained a total sample of 205 people in the process of eviction. A total of 59.5% (n=122) were women, and 40.5% (n=83) were men. Participants were more likely to have poor health (odds ratio [OR]: 12.63, 95% confidence interval [95%CI]: 8.74-18.27), have cardiovascular diseases (OR: 3.08; 95%CI: 1.54- 6.16), or to smoke (OR: 1.68; 95% CI: 1.21-2.33) compared with the Andalusian general population. Most of the health indicators analyzed showed a worse outcome for women undergoing an eviction process. Our results suggest that, in the current context of economic crisis, people undergoing a process of eviction in Granada and its metropolitan area show poorer health than the Andalusian general population. Further research is needed on health and evictions from different methodological approaches, for a better understanding of the topic. Copyright © 2015 SESPAS. Published by Elsevier Espana. All rights reserved.

  6. [Application of traditional Chinese medicine reference standards in quality control of Chinese herbal pieces].

    Science.gov (United States)

    Lu, Tu-Lin; Li, Jin-Ci; Yu, Jiang-Yong; Cai, Bao-Chang; Mao, Chun-Qin; Yin, Fang-Zhou

    2014-01-01

    Traditional Chinese medicine (TCM) reference standards plays an important role in the quality control of Chinese herbal pieces. This paper overviewed the development of TCM reference standards. By analyzing the 2010 edition of Chinese pharmacopoeia, the application of TCM reference standards in the quality control of Chinese herbal pieces was summarized, and the problems exiting in the system were put forward. In the process of improving the quality control level of Chinese herbal pieces, various kinds of advanced methods and technology should be used to research the characteristic reference standards of Chinese herbal pieces, more and more reasonable reference standards should be introduced in the quality control system of Chinese herbal pieces. This article discussed the solutions in the aspect of TCM reference standards, and future development of quality control on Chinese herbal pieces is prospected.

  7. Mechanical engineer's reference book

    CERN Document Server

    Parrish, A

    1973-01-01

    Mechanical Engineer's Reference Book: 11th Edition presents a comprehensive examination of the use of Systéme International d' Unités (SI) metrication. It discusses the effectiveness of such a system when used in the field of engineering. It addresses the basic concepts involved in thermodynamics and heat transfer. Some of the topics covered in the book are the metallurgy of iron and steel; screw threads and fasteners; hole basis and shaft basis fits; an introduction to geometrical tolerancing; mechanical working of steel; high strength alloy steels; advantages of making components as castings

  8. Four-year prospective study of STAPH-IDENT system and conventional method for reference identification of Staphylococcus, Stomatococcus, and Micrococcus spp..

    Science.gov (United States)

    Rhoden, D L; Miller, J M

    1995-01-01

    A 4-year prospective study compared the accuracy of the STAPH-IDENT system (bioMérieux Vitek, Inc., Hazelwood, Mo.) with that of the reference procedure of the Centers for Disease Control and Prevention for the identification of Staphylococcus species, Stomatococcus mucilaginosus, and Micrococcus species. The study compared the results from 1,106 cultures (500 eye cultures, 217 strains submitted for reference identification, and 389 known stock strains) representing 21 species of the family Micrococcaceae. The overall agreement of genus and species identifications was 81.1%. The percent agreement for the five most common clinical isolates was as follows: Staphylococcus epidermidis, 97.1% (517 isolates); Staphylococcus hominis, 82.5% (57 isolates); Staphylococcus aureus, 77.2% (162 isolates); Staphylococcus haemolyticus, 75.8% (61 isolates); and Staphylococcus warneri, 64.1% (39 isolates). The lowest percent agreement was with Staphylococcus cohnii (11.1%; (9 isolates). Of the 217 isolates sent to the Centers for Disease Control and Prevention for identification, 60.4% (131) were correctly identified by the STAPH-IDENT system. Of these, S. epidermidis accounted for 23.9%, S. aureus accounted for 15.6%, S. warneri accounted for 6.9%, Staphylococcus lugdunensis accounted for 6.5%, S. haemolyticus accounted for 5.5%, and S. hominis accounted for 4.1%. The STAPH-IDENT system did not perform adequately when dealing with commonly encountered organisms and is unsuitable for identifying uncommon isolates. PMID:7699074

  9. Modal-space reference-model-tracking fuzzy control of earthquake excited structures

    Science.gov (United States)

    Park, Kwan-Soon; Ok, Seung-Yong

    2015-01-01

    This paper describes an adaptive modal-space reference-model-tracking fuzzy control technique for the vibration control of earthquake-excited structures. In the proposed approach, the fuzzy logic is introduced to update optimal control force so that the controlled structural response can track the desired response of a reference model. For easy and practical implementation, the reference model is constructed by assigning the target damping ratios to the first few dominant modes in modal space. The numerical simulation results demonstrate that the proposed approach successfully achieves not only the adaptive fault-tolerant control system against partial actuator failures but also the robust performance against the variations of the uncertain system properties by redistributing the feedback control forces to the available actuators.

  10. Auditory Warnings, Signal-Referent Relations, and Natural Indicators: Re-Thinking Theory and Application

    Science.gov (United States)

    Petocz, Agnes; Keller, Peter E.; Stevens, Catherine J.

    2008-01-01

    In auditory warning design the idea of the strength of the association between sound and referent has been pivotal. Research has proceeded via constructing classification systems of signal-referent associations and then testing predictions about ease of learning of different levels of signal-referent relation strength across and within different…

  11. Influences on decision-making for undergoing plastic surgery: a mental models and quantitative assessment.

    Science.gov (United States)

    Darisi, Tanya; Thorne, Sarah; Iacobelli, Carolyn

    2005-09-01

    Research was conducted to gain insight into potential clients' decisions to undergo plastic surgery, their perception of benefits and risks, their judgment of outcomes, and their selection of a plastic surgeon. Semistructured, open-ended interviews were conducted with 60 people who expressed interest in plastic surgery. Qualitative analysis revealed their "mental models" regarding influences on their decision to undergo plastic surgery and their choice of a surgeon. Interview results were used to design a Web-based survey in which 644 individuals considering plastic surgery responded. The desire for change was the most direct motivator to undergo plastic surgery. Improvements to physical well-being were related to emotional and social benefits. When prompted about risks, participants mentioned physical, emotional, and social risks. Surgeon selection was a critical influence on decisions to undergo plastic surgery. Participants gave considerable weight to personal consultation and believed that finding the "right" plastic surgeon would minimize potential risks. Findings from the Web-based survey were similar to the mental models interviews in terms of benefit ratings but differed in risk ratings and surgeon selection criteria. The mental models interviews revealed that interview participants were thoughtful about their decision to undergo plastic surgery and focused on finding the right plastic surgeon.

  12. Hepatobiliary transporter expression and post-operative jaundice in patients undergoing partial hepatectomy.

    Science.gov (United States)

    Bernhardt, Gerwin A; Zollner, Gernot; Cerwenka, Herwig; Kornprat, Peter; Fickert, Peter; Bacher, Heinz; Werkgartner, Georg; Müller, Gabriele; Zatloukal, Kurt; Mischinger, Hans-Jörg; Trauner, Michael

    2012-01-01

    Post-operative hyperbilirubinaemia in patients undergoing liver resections is associated with high morbidity and mortality. Apart from different known factors responsible for the development of post-operative jaundice, little is known about the role of hepatobiliary transport systems in the pathogenesis of post-operative jaundice in humans after liver resection. Two liver tissue samples were taken from 14 patients undergoing liver resection before and after Pringle manoeuvre. Patients were retrospectively divided into two groups according to post-operative bilirubin serum levels. The two groups were analysed comparing the results of hepatobiliary transporter [Na-taurocholate cotransporter (NTCP); multidrug resistance gene/phospholipid export pump(MDR3); bile salt export pump (BSEP); canalicular bile salt export pump (MRP2)], heat shock protein 70 (HSP70) expression as well as the results of routinely taken post-operative liver chemistry tests. Patients with low post-operative bilirubin had lower levels of NTCP, MDR3 and BSEP mRNA compared to those with high bilirubin after Pringle manoeuvre. HSP70 levels were significantly higher after ischaemia-reperfusion (IR) injury in both groups resulting in 4.5-fold median increase. Baseline median mRNA expression of all four transporters prior to Pringle manoeuvre tended to be lower in the low bilirubin group whereas expression of HSP70 was higher in the low bilirubin group compared to the high bilirubin group. Higher mRNA levels of HSP70 in the low bilirubin group could indicate a possible protective effect of high HSP70 levels against IR injury. Although the exact role of hepatobiliary transport systems in the development of post-operative hyper bilirubinemia is not yet completely understood, this study provides new insights into the molecular aspects of post-operative jaundice after liver surgery. © 2011 John Wiley & Sons A/S.

  13. Salivary function in patients with chronic renal failure undergoing hemodialysis

    International Nuclear Information System (INIS)

    Kaya, M.; Cermik, T.F.; Uestuen, F.; Sen, S.; Berkarda, S.

    2002-01-01

    The aim of this study was to evaluate the changes in salivary gland function in patients with chronic renal failure (CRF) undergoing hemodialysis. The group consisted of 23 patients with CRF (13 female, 10 male; mean age: 40±13 yr) and 14 healthy control subjects (mean age: 40±13 yr). All underwent dynamic salivary gland scintigraphy with gustatory stimulation. After intravenous administration of 99m Tc pertechnetate, first, perfusion images at 2 seconds per frame were acquired for 1 minute, then dynamic images at 1 minute per frame were acquired for 45 minutes. At 30 minutes after injection , 10 ml lemon juice was given for 15 minutes as a gustatory stimulus. We obtained time-activity curves derived from regions of interest centered over the four major salivary glands. The following functional indices were calculated for each gland: the time of maximum radioactivity (T max ) for the prestimulated period, the time of minimum radioactivity (T min ), as an indicator of velocity of secretion after stimulation, and the Lem E 5 % value as an indicator of the secretion function. When the patients with CRF undergoing hemodialysis were compared to the controls, there were statistically significant differences in T max , T min and Lem E 5 % values for bilateral parotid glands, and T min values for bilateral submandibular glands (p max and Lem E 5 % values for bilateral submandibular glands. There were also significant differences in T max and Lem E 5 % values for bilateral parotid glands between mild oral problems and severe oral problems in patients with CRF (undergoing hemodialysis). In this study, prolonged T max and T min values, and decreased Lem E 5 % values for parotid glands and prolonged T min values for submandibular glands on salivary scintigraphy pointed out decreased parenchymatous and excretory function in patients with CRF undergoing hemodialysis. (author)

  14. Sickle cell disease: reference values and interhemispheric differences of nonimaging transcranial Doppler blood flow parameters.

    Science.gov (United States)

    Arkuszewski, M; Krejza, J; Chen, R; Kwiatkowski, J L; Ichord, R; Zimmerman, R; Ohene-Frempong, K; Desiderio, L; Melhem, E R

    2011-09-01

    TCD screening is widely used to identify children with SCD at high risk of stroke. Those with high mean flow velocities in major brain arteries have increased risk of stroke. Thus, our aim was to establish reference values of interhemispheric differences and ratios of blood flow Doppler parameters in the tICA, MCA, and ACA as determined by conventional TCD in children with sickle cell anemia. Reference limits of blood flow parameters were established on the basis of a consecutive cohort of 56 children (mean age, 100 ± 40 months; range, 29-180 months; 30 females) free of neurologic deficits and intracranial stenosis detectable by MRA, with blood flow velocities <170 cm/s by conventional TCD. Reference limits were estimated by using tolerance intervals, within which are included with a probability of .90 of all possible data values from 95% of a population. Average peak systolic velocities were significantly higher in the right hemisphere in the MCA and ACA (185 ± 28 cm/s versus 179 ± 27 and 152 ± 30 cm/s versus 143 ± 34 cm/s respectively). Reference limits for left-to-right differences in the mean flow velocities were the following: -43 to 33 cm/s for the MCA; -49 to 38 cm/s for the ACA, and -38 to 34 cm/s for the tICA, respectively. Respective reference limits for left-to-right velocity ratios were the following: 0.72 to 1.25 cm/s for the MCA; 0.62 to 1.39 cm/s for the ACA, and 0.69 to 1.27 cm/s for the tICA. Flow velocities in major arteries were inversely related to age and Hct or Hgb. The study provides reference intervals of TCD flow velocities and their interhemispheric differences and ratios that may be helpful in identification of intracranial arterial stenosis in children with SCD undergoing sonographic screening for stroke prevention.

  15. [Establishing biological reference intervals of alanine transaminase for clinical laboratory stored database].

    Science.gov (United States)

    Guo, Wei; Song, Binbin; Shen, Junfei; Wu, Jiong; Zhang, Chunyan; Wang, Beili; Pan, Baishen

    2015-08-25

    To establish an indirect reference interval based on the test results of alanine aminotransferase stored in a laboratory information system. All alanine aminotransferase results were included for outpatients and physical examinations that were stored in the laboratory information system of Zhongshan Hospital during 2014. The original data were transformed using a Box-Cox transformation to obtain an approximate normal distribution. Outliers were identified and omitted using the Chauvenet and Tukey methods. The indirect reference intervals were obtained by simultaneously applying nonparametric and Hoffmann methods. The reference change value was selected to determine the statistical significance of the observed differences between the calculated and published reference intervals. The indirect reference intervals for alanine aminotransferase of all groups were 12 to 41 U/L (male, outpatient), 12 to 48 U/L (male, physical examination), 9 to 32 U/L (female, outpatient), and 8 to 35 U/L (female, physical examination), respectively. The absolute differences when compared with the direct results were all smaller than the reference change value of alanine aminotransferase. The Box-Cox transformation combined with the Hoffmann and Tukey methods is a simple and reliable technique that should be promoted and used by clinical laboratories.

  16. Preliminary measurements of the establishment of a quality control programme for the activimeter calibration reference system

    International Nuclear Information System (INIS)

    Martins, Elaine W.; Potiens, Maria da Penha A.

    2009-01-01

    The nuclear medicine techniques efficiency and safety depends on, beside other factors, a quality control programme, mainly regards to the nuclides activimeter utilization. The Calibration Laboratory of IPEN uses as a work standard, a tertiary standard system Capintec, calibrated at the Accredited Dosimetry Calibration Laboratory of the Medical radiation Research Center - University of Wisconsin. In this work, as preliminary measurements to establish a quality control programme for the activimeter calibration procedures, initially the repeatability and reproducibility (long term stability) tests were performed using a sealed check source of 133 Ba. Later on, to complete this quality control programme other check sources ( 137 Cs, 57 Co, 60 Co) will be used to perform the same tests. A series of 80 experiments of 10 measurements each has been carried out. The reference system showed a good behaviour to the repeatability test, considering the tolerance limits of 5%. The percent deviations of all tested sources in the activity measurements were lower 1% to 133 Ba. (author)

  17. Intravenous clonidine administration and its ability to reduce pulmonary arterial pressure in patients undergoing heart surgery

    Directory of Open Access Journals (Sweden)

    Benedito Barbosa João

    2014-01-01

    Full Text Available Objective: Evaluate the ability of clonidine to reduce pulmonary arterial pressure in patients with pulmonary hypertension undergoing heart surgery, either by reducing the pressure values from the direct measurement of pulmonary arterial pressure or by reducing or eliminating the need for intraoperative dobutamine and nitroprusside. Method: Randomized, double-blind, placebo-controlled, comparative study conducted in 30 patients with pulmonary arterial hypertension type 2 undergoing cardiac surgery. Mean pulmonary arterial pressure and dosage of dobutamine and sodium nitroprusside were assessed four times: before intravenous administration of clonidine (2 μg/kg or placebo (T0, 30 min after tested treatment and before cardiopulmonary bypass (T1, immediately after CPB (T2, 10 min after protamine injection (T3. Results: There were no significant differences regarding mean pulmonary arterial pressure at any time of evaluation. There was no significant difference between groups regarding other variables, such as mean systemic arterial pressure, heart rate, total dose of dobutamine, total dose of sodium nitroprusside, and need for fentanyl. Conclusion: Data analysis from patients included in this study allows us to conclude that intravenous clonidine (2 μg/kg was not able to reduce the mean pulmonary arterial pressure in patients with pulmonary hypertension in group 2 (pulmonary venous hypertension, undergoing heart surgery, or reduce or eliminate the need for intraoperative administration of dobutamine and sodium nitroprusside. Keywords: Clonidine, Pulmonary hypertension, Heart surgery

  18. Direct model reference adaptive control with application to flexible robots

    Science.gov (United States)

    Steinvorth, Rodrigo; Kaufman, Howard; Neat, Gregory W.

    1992-01-01

    A modification to a direct command generator tracker-based model reference adaptive control (MRAC) system is suggested in this paper. This modification incorporates a feedforward into the reference model's output as well as the plant's output. Its purpose is to eliminate the bounded model following error present in steady state when previous MRAC systems were used. The algorithm was evaluated using the dynamics for a single-link flexible-joint arm. The results of these simulations show a response with zero steady state model following error. These results encourage further use of MRAC for various types of nonlinear plants.

  19. Local anesthesia with ropivacaine for patients undergoing laparoscopic cholecystectomy

    Science.gov (United States)

    Liu, Yu-Yin; Yeh, Chun-Nan; Lee, Hsiang-Lin; Wang, Shang-Yu; Tsai, Chun-Yi; Lin, Chih-Chung; Chao, Tzu-Chieh; Yeh, Ta-Sen; Jan, Yi-Yin

    2009-01-01

    AIM: To investigate the effect of pain relief after infusion of ropivacaine at port sites at the end of surgery. METHODS: From October 2006 to September 2007, 72 patients undergoing laparoscopic cholecystectomy (LC) were randomized into two groups of 36 patients. One group received ropivacaine infusion at the port sites at the end of LC and the other received normal saline. A visual analog scale was used to assess postoperative pain when the patient awakened in the operating room, 6 and 24 h after surgery, and before discharge. The amount of analgesics use was also recorded. The demographics, laboratory data, hospital stay, and perioperative complications were compared between the two groups. RESULTS: There was no difference between the two groups preoperatively in terms of demographic and laboratory data. After surgery, similar operation time, blood loss, and no postoperative morbidity and mortality were observed in the two groups. However, a significantly lower pain score was observed in the patients undergoing LC with local anesthesia infusion at 1 h after LC and at discharge. Regarding analgesic use, the amount of meperidine used 1 h after LC and the total used during admission were lower in patients undergoing LC with local anesthesia infusion. This group also had a shorter hospital stay. CONCLUSION: Local anesthesia with ropivacaine at the port site in LC patients significantly decreased postoperative pain immediately. This explains the lower meperidine use and earlier discharge for these patients. PMID:19452582

  20. Predicting blood transfusion in patients undergoing minimally invasive oesophagectomy.

    Science.gov (United States)

    Schneider, Crispin; Boddy, Alex P; Fukuta, Junaid; Groom, William D; Streets, Christopher G

    2014-12-01

    To evaluate predictors of allogenic blood transfusion requirements in patients undergoing minimal invasive oesophagectomy at a tertiary high volume centre for oesophago-gastric surgery. Retrospective analysis of all patients undergoing minimal access oesophagectomy in our department between January 2010 and December 2011. Patients were divided into two groups depending on whether they required a blood transfusion at any time during their index admission. Factors that have been shown to influence perioperative blood transfusion requirements in major surgery were included in the analysis. Binary logistic regression analysis was performed to determine the impact of patient and perioperative characteristics on transfusion requirements during the index admission. A total of 80 patients underwent minimal access oesophagectomy, of which 61 patients had a laparoscopic assisted oesophagectomy and 19 patients had a minimal invasive oesophagectomy. Perioperative blood transfusion was required in 28 patients at any time during hospital admission. On binary logistic regression analysis, a lower preoperative haemoglobin concentration (p blood transfusion requirements. It has been reported that requirement for blood transfusion can affect long-term outcomes in oesophageal cancer resection. Two factors which could be addressed preoperatively; haemoglobin concentration and type of oesophageal resection, may be valuable in predicting blood transfusions in patients undergoing minimally invasive oesophagectomy. Our analysis revealed that preoperative haemoglobin concentration, occurrence of significant complications and type of minimal access oesophagectomy predicted blood transfusion requirements in the patient population examined. Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

  1. Clostridium difficile colitis in patients undergoing lumbar spine surgery.

    Science.gov (United States)

    Skovrlj, Branko; Guzman, Javier Z; Silvestre, Jason; Al Maaieh, Motasem; Qureshi, Sheeraz A

    2014-09-01

    Retrospective database analysis. To investigate incidence, comorbidities, and impact on health care resources of Clostridium difficile infection after lumbar spine surgery. C. difficile colitis is reportedly increasing in hospitalized patients and can have a negative impact on patient outcomes. No data exist on estimates of C. difficile infection rates and its consequences on patient outcomes and health care resources among patients undergoing lumbar spine surgery. The Nationwide Inpatient Sample was examined from 2002 to 2011. Patients were included for study based on International Classification of Diseases, Ninth Revision, Clinical Modification, procedural codes for lumbar spine surgery for degenerative diagnoses. Baseline patient characteristics were determined and multivariable analyses assessed factors associated with increased incidence of C. difficile and risk of mortality. The incidence of C. difficile infection in patients undergoing lumbar spine surgery is 0.11%. At baseline, patients infected with C. difficile were significantly older (65.4 yr vs. 58.9 yr, Pinfection. Small hospital size was associated with decreased odds (odds ratio [OR], 0.5; Pinfection. Uninsured (OR, 1.62; Pinfection. C. difficile increased hospital length of stay by 8 days (Pdifficile infection after lumbar spine surgery carries a 36.4-fold increase in mortality and costs approximately $10,658,646 per year to manage. These data suggest that great care should be taken to avoid C. difficile colitis in patients undergoing lumbar spine surgery because it is associated with longer hospital stays, greater overall costs, and increased inpatient mortality. 3.

  2. IAEA biological reference materials

    International Nuclear Information System (INIS)

    Parr, R.M.; Schelenz, R.; Ballestra, S.

    1988-01-01

    The Analytical Quality Control Services programme of the IAEA encompasses a wide variety of intercomparisons and reference materials. This paper reviews only those aspects of the subject having to do with biological reference materials. The 1988 programme foresees 13 new intercomparison exercises, one for major, minor and trace elements, five for radionuclides, and seven for stable isotopes. Twenty-two natural matrix biological reference materials are available: twelve for major, minor and trace elements, six for radionuclides, and four for chlorinated hydrocarbons. Seven new intercomparisons and reference materials are in preparation or under active consideration. Guidelines on the correct use of reference materials are being prepared for publication in 1989 in consultation with other major international producers and users of biological reference materials. The IAEA database on available reference materials is being updated and expanded in scope, and a new publication is planned for 1989. (orig.)

  3. Standard Reference Tables -

    Data.gov (United States)

    Department of Transportation — The Standard Reference Tables (SRT) provide consistent reference data for the various applications that support Flight Standards Service (AFS) business processes and...

  4. Do patients fear undergoing general anesthesia for oral surgery?

    Science.gov (United States)

    Elmore, Jasmine R; Priest, James H; Laskin, Daniel M

    2014-01-01

    Many patients undergoing major surgery have more fear of the general anesthesia than the procedure. This appears to be reversed with oral surgery. Therefore, patients need to be as well informed about this aspect as the surgical operation.

  5. Gonad Shielding for Patients Undergoing Conventional Radiological Examinations: Is There Cause for Concern?

    OpenAIRE

    Karami; Zabihzadeh; Gholami

    2016-01-01

    Background Gonad shielding is one of the fundamental methods by which to protect reproductive organs in patients undergoing conventional radiological examinations. A lack of or inadequate shielding of the gonads may increase the exposure of these organs and result in malignancies future generations. Objectives The aim of this study is to investigate the prevalence of gonad shielding in patients undergoing conventional radiological...

  6. Stevens Johnson Syndrome in a patient undergoing gynaecological brachytherapy: An association or an incident?

    International Nuclear Information System (INIS)

    Ferreira, M. R.; Amado, A.; Jorge, M.; Grillo, I. M.

    2011-01-01

    Background: Stevens Johnson Syndrome and Erythema Multiforme are hypersensitivity skin reactions generally arising in the context of multiple causes. Radiation therapy is considered to be one of these causes, although most reports are hindered by concomitant medications. Aim: The aim of this paper was to present a case of Stevens Johnson Syndrome arising in a patient undergoing gynaecological brachytherapy with an unusual presentation. Case:We describe a case of a 56-year-old woman with endometrial cancer undergoing adjuvant gynaecological radiotherapy. While undergoing a gynaecological brachytherapy boost, she developed bilateral conjunctivitis that progressed to oral mucositis and pruritic erythema with sloughing of the skin on her arms and legs but not the torso or irradiated fields (namely the vaginal mucosa). Conclusion: This case illustrates the association of RT/SJS; however, it also raises the question of patients undergoing RT being more susceptible to SJS as opposed to a direct cause of the disease. (authors)

  7. Establishing a business process reference model for Universities

    DEFF Research Database (Denmark)

    Svensson, Carsten; Hvolby, Hans-Henrik

    2012-01-01

    Modern universities are by any standard complex organizations that, from an IT perspective, present a number of unique challenges. This paper will propose establishing a business process reference framework. The benefit to the users would be a better understanding of the system landscape, business......) have gained popularity among organizations in both the private and public sectors. We speculate that this success can be replicated in a university setting. Furthermore the paper will outline how the research group suggests moving ahead with the research which will lead to a reference model....

  8. Importance of quality aspects of GP care among ethnic minorities: role of cultural attitudes, language and healthcare system of reference.

    Science.gov (United States)

    Lamkaddem, Majda; Spreeuwenberg, Peter M; Devillé, Walter L; Foets, Marleen M; Groenewegen, Peter P

    2012-02-01

    This study examines the mechanisms responsible for ethnic differences in perceived quality of care in The Netherlands. The specific role of cultural attitudes, language proficiency, and the health system in the country of origin was examined, taking socio-demographic characteristics into account. Interview data of 1339 respondents of Moroccan, Turkish, Surinamese and Antillean origin were combined with interview data of Dutch respondents (n = 405) and of Western immigrants (n = 102) in The Netherlands and of a random sample of Dutch privately or publicly insured persons (n = 9675). Data collection took place within the Second Dutch National Survey of General Practice (DNSGP-2, 2001). Items from the QUality Of care Through the patient's Eyes (QUOTE) questionnaire were used to measure expectations, as well as items from the QUOTE-Mi (adapted version for migrant groups). Items on normative orientations were used to measure cultural attitudes. In contrast to our hypothesis, respondents with more egalitarian/modern attitudes attached less importance to quality aspects related to access and quality. Tests on the role of the health system of reference were generally conclusive, showing that respondents accustomed to (parts of) another system have different expectations regarding several aspects of general practitioner healthcare quality, e.g. access to specialist care. Besides socio-demographic characteristics, culture influences patients' expectations regarding general practitioner care quality. However, the role of culture can be more clearly ascribed to the characteristics of the health system which is held as the reference than to the general attitudes on normative orientations.

  9. Carotid disease in diabetic patients undergoing coronary artery bypass grafting

    International Nuclear Information System (INIS)

    Shahid, M.; Abid, A.R.; Dar, M.A.; Noeman, A.; Amin, S.; Azhar, M.

    2012-01-01

    Objective: To compare the severity of carotid artery disease in diabetic and non-diabetic patients undergoing coronary artery bypass grafting. Methods: From January to June 2008, 379 patients undergoing elective coronary artery bypass surgery were preoperatively evaluated for the presence of carotid stenoses by duplex scanning. Patients were divided into two groups, Group I, 156 (41.2%) diabetic patients and Group II, 223 (58.8%) non-diabetic patients. Results: There were 314 (82.8%) males and 65 (17.2%) females with a mean age of 57.2+-9.1 years. In diabetic group there were 125 (80.1%) males and 31 (19.9%) females with a mean age of 56.3+-8.9 years. Left main stem stenosis was present in 59 (37.8%) diabetics and 45 (20.2%) non-diabetics (p 70% stenosis was present in 20 (5.3%) with 13 (8.3%) diabetics and 7 (3.1%) non-diabetics (p<0.025). Stenosis of 50-70% was observed in 30 (7.9%) of which 17 (10.9%) were diabetics and 13 (5.8%) were non-diabetics. Conclusion: Presence of diabetes mellitus is associated with diffuse coronary artery disease and significant carotid artery disease in patients undergoing coronary artery bypass grafting. (author)

  10. Evaluation of the PREVI® Isola automated seeder system compared to reference manual inoculation for antibiotic susceptibility testing by the disk diffusion method.

    Science.gov (United States)

    Le Page, S; van Belkum, A; Fulchiron, C; Huguet, R; Raoult, D; Rolain, J-M

    2015-09-01

    The disk diffusion (DD) method remains the most popular manual technique for antibiotic susceptibility testing (AST) in clinical microbiology laboratories. This is because of its simplicity, reproducibility, and limited cost compared to (automated) microdilution systems, which are usually less sensitive at detecting certain important mechanisms of resistance. Here, we evaluate the PREVI® Isola automated seeder system using a new protocol for spreading bacterial suspensions (eight deposits of calibrated inocula of bacteria, followed by two rounds of rotation) in comparison with manual DD reference testing on a large series of clinical and reference strains. The average time required for seeding one agar plate for DD with this new protocol was 51 s per plate, i.e., 70 agar plates/h. Reproducibility and repeatability was assessed on three reference and three randomly chosen clinical strains, as usually requested by the European Committee on Antimicrobial Susceptibility Testing (EUCAST), and was excellent compared to the manual method. The standard deviations of zones of growth inhibition showed no statistical discrimination. The correlation between the two methods, assessed using 294 clinical isolates and a panel of six antibiotics (n = 3,528 zones of growth inhibition measured), was excellent, with a correlation coefficient of 0.977. The new PREVI® Isola protocol adapted for DD had a sensitivity of 99 % and a specificity of 100 % compared to the manual technique for interpreting DD as recommended by the EUCAST.

  11. Oscillating red giants in eclipsing binary systems: empirical reference value for asteroseismic scaling relation

    Science.gov (United States)

    Themeßl, N.; Hekker, S.; Southworth, J.; Beck, P. G.; Pavlovski, K.; Tkachenko, A.; Angelou, G. C.; Ball, W. H.; Barban, C.; Corsaro, E.; Elsworth, Y.; Handberg, R.; Kallinger, T.

    2018-05-01

    The internal structures and properties of oscillating red-giant stars can be accurately inferred through their global oscillation modes (asteroseismology). Based on 1460 days of Kepler observations we perform a thorough asteroseismic study to probe the stellar parameters and evolutionary stages of three red giants in eclipsing binary systems. We present the first detailed analysis of individual oscillation modes of the red-giant components of KIC 8410637, KIC 5640750 and KIC 9540226. We obtain estimates of their asteroseismic masses, radii, mean densities and logarithmic surface gravities by using the asteroseismic scaling relations as well as grid-based modelling. As these red giants are in double-lined eclipsing binaries, it is possible to derive their independent dynamical masses and radii from the orbital solution and compare it with the seismically inferred values. For KIC 5640750 we compute the first spectroscopic orbit based on both components of this system. We use high-resolution spectroscopic data and light curves of the three systems to determine up-to-date values of the dynamical stellar parameters. With our comprehensive set of stellar parameters we explore consistencies between binary analysis and asteroseismic methods, and test the reliability of the well-known scaling relations. For the three red giants under study, we find agreement between dynamical and asteroseismic stellar parameters in cases where the asteroseismic methods account for metallicity, temperature and mass dependence as well as surface effects. We are able to attain agreement from the scaling laws in all three systems if we use Δνref, emp = 130.8 ± 0.9 μHz instead of the usual solar reference value.

  12. [Evaluation of psychological fear in children undergoing head-up tilt test].

    Science.gov (United States)

    Chu, Wei-Hong; Wu, Li-Jia; Wang, Cheng; Lin, Ping; Li, Fang; Zhu, Li-Ping; Ran, Jing; Zou, Run-Mei; Liu, De-Yu

    2014-03-01

    To investigate the effects of different tilt angles of head-up tilt test (HUTT) and different responses to HUTT on the psychological fear in children undergoing the test. HUTT was performed on children with unexplained syncope or pre-syncope (107 cases: 52 males and 55 females), aged 5.5-17.8 years (mean 12.0±2.8 years). All subjects were randomly assigned to undergo HUTT at an angle of 60°, 70° or 80°; the negative cases underwent sublingual nitroglycerin-provocation HUTT at the same tilt angle. The Wong-Baker Faces Pain Rating Scale was used for self-assessment of psychological fear in subjects during HUTT at the end point of the test. The positive rate, hemodynamic changes and distribution of response types showed no significant differences between children at tilt angles of 60°, 70° and 80° (P>0.05). The greater the tilt angle, the higher the degree of psychological fear in children undergoing the test, but there were no significant differences between them (P>0.05). The degree of psychological fear in children who showed a positive response to HUTT (n=76) was significantly higher than that in children who showed a negative response (n=31) (Pfear in children undergoing the test, and the degree of psychological fear increases in children tested at tilt angles from 60° to 80°, but the differences have no statistical significance. A positive response to HUTT can significantly increase the psychological fear in children.

  13. 7 CFR 300.4 - Reference Manual B.

    Science.gov (United States)

    2010-01-01

    ..., 2001, by the National Seed Health System (NSHS), has been approved for incorporation by reference in 7... inspection at the APHIS Library, U.S. Department of Agriculture, 4700 River Road, Riverdale, MD or at the... the APHIS Web site at http://www.aphis.usda.gov/ppq/pim/accreditation. ...

  14. Development of Postoperative Diabetes Mellitus in Patients Undergoing Distal Pancreatectomy versus Whipple Procedure.

    Science.gov (United States)

    Nguyen, Adrienne; Demirjian, Aram; Yamamoto, Maki; Hollenbach, Kathryn; Imagawa, David K

    2017-10-01

    Because the islets of Langerhans are more prevalent in the body and tail of the pancreas, distal pancreatectomy (DP) is believed to increase the likelihood of developing new onset diabetes mellitus (NODM). To determine whether the development of postoperative diabetes was more prevalent in patients undergoing DP or Whipple procedure, 472 patients undergoing either a DP (n = 122) or Whipple (n = 350), regardless of underlying pathology, were analyzed at one month postoperatively. Insulin or oral hypoglycemic requirements were assessed and patients were stratified into preoperative diabetic status: NODM or preexisting diabetes. A retrospective chart review of the 472 patients between 1996 and 2014 showed that the total rate of NODM after Whipple procedure was 43 per cent, which was not different from patients undergoing DP (45%). The incidence of preoperative diabetes was 12 per cent in patients undergoing the Whipple procedure and 17 per cent in the DP cohort. Thus, the overall incidence of diabetes after Whipple procedure was 54 and 49 per cent in the DP group. The development of diabetes was unrelated to the type of resection performed. Age more than 65 and Caucasian ethnicity were associated with postoperative diabetes regardless of the type of resection performed.

  15. Reference Intervals of Common Clinical Chemistry Analytes for Adults in Hong Kong.

    Science.gov (United States)

    Lo, Y C; Armbruster, David A

    2012-04-01

    Defining reference intervals is a major challenge because of the difficulty in recruiting volunteers to participate and testing samples from a significant number of healthy reference individuals. Historical literature citation intervals are often suboptimal because they're be based on obsolete methods and/or only a small number of poorly defined reference samples. Blood donors in Hong Kong gave permission for additional blood to be collected for reference interval testing. The samples were tested for twenty-five routine analytes on the Abbott ARCHITECT clinical chemistry system. Results were analyzed using the Rhoads EP evaluator software program, which is based on the CLSI/IFCC C28-A guideline, and defines the reference interval as the 95% central range. Method specific reference intervals were established for twenty-five common clinical chemistry analytes for a Chinese ethnic population. The intervals were defined for each gender separately and for genders combined. Gender specific or combined gender intervals were adapted as appropriate for each analyte. A large number of healthy, apparently normal blood donors from a local ethnic population were tested to provide current reference intervals for a new clinical chemistry system. Intervals were determined following an accepted international guideline. Laboratories using the same or similar methodologies may adapt these intervals if deemed validated and deemed suitable for their patient population. Laboratories using different methodologies may be able to successfully adapt the intervals for their facilities using the reference interval transference technique based on a method comparison study.

  16. Preoperative Thyroid Ultrasound Is Indicated in Patients Undergoing Parathyroidectomy for Primary Hyperparathyroidism

    Directory of Open Access Journals (Sweden)

    Cletus A. Arciero, Zita S. Shiue, Jeremy D. Gates, George E. Peoples, Alan P. B. Dackiw, Ralph P. Tufano, Steven K. Libutti, Martha A. Zeiger, Alexander Stojadinovic

    2012-01-01

    Full Text Available Background: Primary hyperaparathyroidism (pHPT is often accompanied by underlying thyroid pathology that can confound preoperative parathyroid localization studies and complicate intra-operative decision making. The aim of this study was to examine the utility of preoperative thyroid ultrasonography (US in patients prior to undergoing parathyroidectomy for pHPT.Methods: An Institutional Review Board approved prospective study was undertaken from January 2005 through July 2008. All patients with pHPT meeting inclusion criteria (n=94 underwent preoperative thyroid ultrasound in addition to standard 99mTc-sestamibi scintigraphy for parathyroid localization. Demographics, operative management and final pathology were examined in all cases.Results: Fifty-four of the 94 patients (57% were noted to have a thyroid nodule on preoperative US, of which 30 (56% underwent further examination with fine needle aspiration biopsy. Alteration of the operative plan attributable to underlying thyroid pathology occurred in 16 patients (17%, with patients undergoing either total thyroidectomy (n=9 or thyroid lobectomy (n=7. Thyroid cancer was noted in 33% of patients undergoing thyroid resection, and 6% of all patients with HPT.Conclusions: The routine utilization of preoperative thyroid ultrasound in patients prior to undergoing parathyroid surgery for pHPT is indicated. The added information from this non-invasive modality facilitates timely management of co-incidental, and sometimes malignant, thyroid pathology.

  17. Post-operative morbidity of the obese patient undergoing posterior ...

    African Journals Online (AJOL)

    Outcome measures: Post-operative morbidity measures – infection, seroma, pulmonary embolism, urinary tract infection, neurological injury and dural tears. Methods: One hundred consecutive patients undergoing posterior lumbar spine surgery were enrolled in the study. Three fellowship trained attending orthopaedic ...

  18. Reference trajectory tracking for a multi-DOF robot arm

    Directory of Open Access Journals (Sweden)

    Krasňanský Róbert

    2015-12-01

    Full Text Available This paper presents the problem of tracking the generated reference trajectory by the simulation model of a multi-DOF robot arm. The kinematic transformation between task space and joint configuration coordinates is nonlinear and configuration dependent. To obtain the solution of the forward kinematics problem, the homogeneous transformation matrix is used. A solution to the inverse kinematics is a vector of joint configuration coordinates calculated using of pseudoinverse Jacobian technique. These coordinates correspond to a set of task space coordinates. The algorithm is presented which uses iterative solution and is simplified by considering stepper motors in robot arm joints. The reference trajectory in Cartesian coordinate system is generated on-line by the signal generator previously developed in MS Excel. Dynamic Data Exchange communication protocol allows sharing data with Matlab-Simulink. These data represent the reference tracking trajectory of the end effector. Matlab-Simulink software is used to calculate the representative joint rotations. The proposed algorithm is demonstrated experimentally on the model of 7-DOF robot arm system.

  19. Tv & video engineer's reference book

    CERN Document Server

    Jackson, K G

    1991-01-01

    TV & Video Engineer's Reference Book presents an extensive examination of the basic television standards and broadcasting spectrum. It discusses the fundamental concepts in analogue and digital circuit theory. It addresses studies in the engineering mathematics, formulas, and calculations. Some of the topics covered in the book are the conductors and insulators, passive components, alternating current circuits; broadcast transmission; radio frequency propagation; electron optics in cathode ray tube; color encoding and decoding systems; television transmitters; and remote supervision of unatten

  20. Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.

    Science.gov (United States)

    Myles, Paul S; Smith, Julian A; Forbes, Andrew; Silbert, Brendan; Jayarajah, Mohandas; Painter, Thomas; Cooper, D James; Marasco, Silvana; McNeil, John; Bussières, Jean S; McGuinness, Shay; Byrne, Kelly; Chan, Matthew T V; Landoni, Giovanni; Wallace, Sophie

    2017-01-12

    Tranexamic acid reduces the risk of bleeding among patients undergoing cardiac surgery, but it is unclear whether this leads to improved outcomes. Furthermore, there are concerns that tranexamic acid may have prothrombotic and proconvulsant effects. In a trial with a 2-by-2 factorial design, we randomly assigned patients who were scheduled to undergo coronary-artery surgery and were at risk for perioperative complications to receive aspirin or placebo and tranexamic acid or placebo. The results of the tranexamic acid comparison are reported here. The primary outcome was a composite of death and thrombotic complications (nonfatal myocardial infarction, stroke, pulmonary embolism, renal failure, or bowel infarction) within 30 days after surgery. Of the 4662 patients who were enrolled and provided consent, 4631 underwent surgery and had available outcomes data; 2311 were assigned to the tranexamic acid group and 2320 to the placebo group. A primary outcome event occurred in 386 patients (16.7%) in the tranexamic acid group and in 420 patients (18.1%) in the placebo group (relative risk, 0.92; 95% confidence interval, 0.81 to 1.05; P=0.22). The total number of units of blood products that were transfused during hospitalization was 4331 in the tranexamic acid group and 7994 in the placebo group (Ptranexamic acid group and in 2.8% of the patients in the placebo group (P=0.001), and seizures occurred in 0.7% and 0.1%, respectively (P=0.002 by Fisher's exact test). Among patients undergoing coronary-artery surgery, tranexamic acid was associated with a lower risk of bleeding than was placebo, without a higher risk of death or thrombotic complications within 30 days after surgery. Tranexamic acid was associated with a higher risk of postoperative seizures. (Funded by the Australian National Health and Medical Research Council and others; ATACAS Australia New Zealand Clinical Trials Registry number, ACTRN12605000557639 .).