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Sample records for receiver coil correlation

  1. High-resolution imaging of the layers of the gastrointestinal wall of pig and human specimens using an endoluminal MR receiver coil. Correlation to histology

    International Nuclear Information System (INIS)

    Kramer, Sebastian; Palmowski, M.; Macher-Goeppinger, S.; Mueller, M.; Volke, F.; Duex, M.; Kauczor, H.U.; Grenacher, L.

    2009-01-01

    Purpose: High-resolution MR imaging of the layers of the gastrointestinal wall to provide a foundation for tumor staging based on morphological criteria. Materials and Methods: Over a period of 12 months, miscellaneous parts of the gastrointestinal tract of 15 human specimens and 30 porcine specimens were scanned using a 1.5 Tesla clinical MRI scanner combined with an endoluminal receiver coil. The sequences used were T1-weighted opposed-phase, T2-weighted turbo spin echo with fat saturation and fast T2-weighted inversion recovery. The number of differentiable layers, their width and the signal intensity were documented. Then, the results were compared with histological specimens in order to link the imaged wall layers to the anatomical layers. Spearman's Rank Correlation was used to determine the soundness of the link between the images and their related histology. Results: For both human and animal specimens, the MRI scanning produced 3 to 5, maximum 6 (pig), differentiable layers. The mucosa, submucosa and muscularis could be differentiated with a hyperintense, hypointense and intermediary signal, respectively. The subserosal layer displayed a hypointense signal. Conclusion: High-resolution MRI is able to produce differentiable images of the anatomical layers of the gastrointestinal wall in both humans and pigs. Accordingly, it is possible to use MR imaging to diagnose the extent of local tumor infiltration of the gastrointestinal wall. (orig.)

  2. T2-weighted prostate MRI at 7 Tesla using a simplified external transmit-receive coil array: correlation with radical prostatectomy findings in two prostate cancer patients.

    Science.gov (United States)

    Rosenkrantz, Andrew B; Zhang, Bei; Ben-Eliezer, Noam; Le Nobin, Julien; Melamed, Jonathan; Deng, Fang-Ming; Taneja, Samir S; Wiggins, Graham C

    2015-01-01

    To report design of a simplified external transmit-receive coil array for 7 Tesla (T) prostate MRI, including demonstration of the array for tumor localization using T2-weighted imaging (T2WI) at 7T before prostatectomy. Following simulations of transmitter designs not requiring parallel transmission or radiofrequency-shimming, a coil array was constructed using loop elements, with anterior and posterior rows comprising one transmit-receive element and three receive-only elements. This coil structure was optimized using a whole-body phantom. In vivo sequence optimization was performed to optimize achieved flip angle (FA) and signal to noise ratio (SNR) in prostate. The system was evaluated in a healthy volunteer at 3T and 7T. The 7T T2WI was performed in two prostate cancer patients before prostatectomy, and localization of dominant tumors was subjectively compared with histopathological findings. Image quality was compared between 3T and 7T in these patients. Simulations of the B1(+) field in prostate using two-loop design showed good magnitude (B1(+) of 0.245 A/m/w(1/2)) and uniformity (nonuniformity [SD/mean] of 10.4%). In the volunteer, 90° FA was achieved in prostate using 225 v 1 ms hard-pulse (indicating good efficiency), FA maps confirmed good uniformity (14.1% nonuniformity), and SNR maps showed SNR gain of 2.1 at 7T versus 3T. In patients, 7T T2WI showed excellent visual correspondence with prostatectomy findings. 7T images demonstrated higher estimated SNR (eSNR) in benign peripheral zone (PZ) and tumor compared with 3T, but lower eSNR in fat and slight decreases in tumor-to-PZ contrast and PZ-homogeneity. We have demonstrated feasibility of a simplified external coil array for high-resolution T2-weighted prostate MRI at 7T. © 2013 Wiley Periodicals, Inc.

  3. Materials and methods for higher performance screen-printed flexible MRI receive coils.

    Science.gov (United States)

    Corea, Joseph R; Lechene, P Balthazar; Lustig, Michael; Arias, Ana C

    2017-08-01

    To develop methods for characterizing materials used in screen-printed MRI coils and improve signal-to-noise ratio (SNR) with new lower-loss materials. An experimental apparatus was created to characterize dielectric properties of plastic substrates used in receive coils. Coils were fabricated by screen printing conductive ink onto several plastic substrates. Unloaded and sample loaded quality factor (Q Unloaded /Q Loaded ) measurements and scans on a 3T scanner were used to characterize coil performance. An experimental method was developed to describe the relationship between a coil's Q Unloaded and the SNR it provides in images of a phantom. In addition, 3T scans of a phantom and the head of a volunteer were obtained with a proof-of-concept printed eight-channel array, and the results were compared with a commercial 12-channel array. Printed coils with optimized substrates exhibited up to 97% of the image SNR when compared with a traditional coil on a loading phantom. Q Unloaded and the SNR of coils were successfully correlated. The printed array resulted in images comparable to the quality given by the commercial array. Using the proposed methods and materials, the SNR of printed coils approached that of commercial coils while using a new fabrication technique that provided more flexibility and close contact with the patient's body. Magn Reson Med 78:775-783, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  4. MR-based conductivity imaging using multiple receiver coils.

    Science.gov (United States)

    Lee, Joonsung; Shin, Jaewook; Kim, Dong-Hyun

    2016-08-01

    To propose a signal combination method for MR-based tissue conductivity mapping using a standard clinical scanner with multiple receiver coils. The theory of the proposed method is presented with two practical approaches, a coil-specific approach and a subject-specific approach. Conductivity maps were reconstructed using the transceive phase of the combined signal. The sensitivities of the coefficients used for signal combination were analyzed and the method was compared with other signal combination methods. For validation, multiple receiver brain coils and multiple receiver breast coils were used in phantom, in vivo brain, and in vivo breast studies. The variation among the conductivity estimates was conductivity estimates. MR-based tissue conductivity mapping is feasible when using a standard clinical MR scanner with multiple receiver coils. The proposed method reduces systematic errors in phase-based conductivity mapping that can occur due to the inhomogeneous magnitude of the combined receive profile. Magn Reson Med 76:530-539, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  5. Practical aspects of 13C surface receive coils with active decoupling and tuning circuit

    DEFF Research Database (Denmark)

    Nilsson, Daniel; Mohr, Johan Jacob; Zhurbenko, Vitaliy

    2012-01-01

    is based on application-specified coil profile and includes impedance matching and balancing circuits. Active decoupling is implemented in order to minimize the influence of the receiving coil on the homogeneity of the transmit-coil field. Measurement results for a coil prototype are presented, including...

  6. A high temperature superconductor tape RF receiver coil for a low field magnetic resonance imaging system

    International Nuclear Information System (INIS)

    Cheng, M C; Yan, B P; Lee, K H; Ma, Q Y; Yang, E S

    2005-01-01

    High temperature superconductor (HTS) thin films have been applied in making a low loss RF receiver coil for improving magnetic resonance imaging image quality. However, the application of these coils is severely limited by their limited field of view (FOV). Stringent fabrication environment requirements and high cost are further limitations. In this paper, we propose a simpler method for designing and fabricating HTS coils. Using industrial silver alloy sheathed Bi (2-x) Pb x Sr 2 Ca 2 Cu 3 O 10 (Bi-2223) HTS tapes, a five-inch single-turn HTS solenoid coil has been developed, and human wrist images have been acquired with this coil. The HTS tape coil has demonstrated an enhanced FOV over a six-inch YBCO thin film surface coil at 77 K with comparable signal-to-noise ratio

  7. Tracking method of small receiver coil using MR scanner

    International Nuclear Information System (INIS)

    Onogi, Shinya; Liao, Hongen; Kobayashi, Etsuko; Sakuma, Ichiro; Watanabe, Sigeru

    2007-01-01

    MR guided surgery is quite effective in realizing accurate and safe minimally invasive surgery (MIS). The combination of intra-operative MRI, surgical navigation system, and surgical robot should be of practical use in the field of MIS in the future. When we use flexible endoscope type robotic manipulator, the position and the orientation of the tip point of the flexible forceps should be navigated and controlled by a robotic manipulator. However, the conventional position sensor can not be used because of the strong magnetic field and the limited workspace. We propose a novel tracking method named extended active tracking (EAT), which is based on the active tracking algorithm. EAT can measure the position and the orientation of the tracking coils synchronically. The principle of EAT is three points measurement by three series inductance. We can calculate the orientation of three coils using the measured 3-D positions of coils. In this paper, three experiments was conducted to evaluate the basic performance of the EAT. First experiment is the flip angle adjustment for the reduction of background noise, which is caused by the proton around each inductance. The experimental results shown that the inductance positions could be clearly observed without background noise at 6-deg flip angle with nuclear magnetic resonance (NMR) signal peaks. Second experiment is the reproducibility evaluation. The fluctuation of measurement position and orientation were less than 0.3 mm (SD) and 1.0 deg (SD) at various positions and orientations. And standard deviation of the distance between the inductances at various positions and orientations is less than resolution (0.78 mm). Third experiment is an accuracy evaluation. The position measurement accuracy was 0.39 mm (RMS) using an optical tracking device. The orientation measurement accuracy was 3.5 deg (RMS) when the tracking coil was rotated 30 degree. Evaluation result suggests that EAT is possible to be used inside a patient body

  8. A 128-channel receive-only cardiac coil for highly accelerated cardiac MRI at 3 Tesla.

    Science.gov (United States)

    Schmitt, Melanie; Potthast, Andreas; Sosnovik, David E; Polimeni, Jonathan R; Wiggins, Graham C; Triantafyllou, Christina; Wald, Lawrence L

    2008-06-01

    A 128-channel receive-only array coil is described and tested for cardiac imaging at 3T. The coil is closely contoured to the body with a "clam-shell" geometry with 68 posterior and 60 anterior elements, each 75 mm in diameter, and arranged in a continuous overlapped array of hexagonal symmetry to minimize nearest neighbor coupling. Signal-to-noise ratio (SNR) and noise amplification for parallel imaging (G-factor) were evaluated in phantom and volunteer experiments. These results were compared to those of commercially available 24-channel and 32-channel coils in routine use for cardiac imaging. The in vivo measurements with the 128-channel coil resulted in SNR gains compared to the 24-channel coil (up to 2.2-fold in the apex). The 128- and 32-channel coils showed similar SNR in the heart, likely dominated by the similar element diameters of these coils. The maximum G-factor values were up to seven times better for a seven-fold acceleration factor (R=7) compared to the 24-channel coil and up to two-fold improved compared to the 32-channel coil. The ability of the 128-channel coil to facilitate highly accelerated cardiac imaging was demonstrated in four volunteers using acceleration factors up to seven-fold (R=7) in a single spatial dimension. Copyright (c) 2008 Wiley-Liss, Inc.

  9. 96-Channel receive-only head coil for 3 Tesla: design optimization and evaluation.

    Science.gov (United States)

    Wiggins, Graham C; Polimeni, Jonathan R; Potthast, Andreas; Schmitt, Melanie; Alagappan, Vijay; Wald, Lawrence L

    2009-09-01

    The benefits and challenges of highly parallel array coils for head imaging were investigated through the development of a 3T receive-only phased-array head coil with 96 receive elements constructed on a close-fitting helmet-shaped former. We evaluated several designs for the coil elements and matching circuitry, with particular attention to sources of signal-to-noise ratio (SNR) loss, including various sources of coil loading and coupling between the array elements. The SNR and noise amplification (g-factor) in accelerated imaging were quantitatively evaluated in phantom and human imaging and compared to a 32-channel array built on an identical helmet-shaped former and to a larger commercial 12-channel head coil. The 96-channel coil provided substantial SNR gains in the distal cortex compared to the 12- and 32-channel coils. The central SNR for the 96-channel coil was similar to the 32-channel coil for optimum SNR combination and 20% lower for root-sum-of-squares combination. There was a significant reduction in the maximum g-factor for 96 channels compared to 32; for example, the 96-channel maximum g-factor was 65% of the 32-channel value for acceleration rate 4. The performance of the array is demonstrated in highly accelerated brain images.

  10. Impact of magnetic field strength and receiver coil in ocular MRI: a phantom and patient study.

    Science.gov (United States)

    Erb-Eigner, K; Warmuth, C; Taupitz, M; Willerding, G; Bertelmann, E; Asbach, P

    2013-09-01

    Generally, high-resolution MRI of the eye is performed with small loop surface coils. The purpose of this phantom and patient study was to investigate the influence of magnetic field strength and receiver coils on image quality in ocular MRI. The eyeball and the complex geometry of the facial bone were simulated by a skull phantom with swine eyes. MR images were acquired with two small loop surface coils with diameters of 4 cm and 7 cm and with a multi-channel head coil at 1.5 and 3 Tesla, respectively. Furthermore, MRI of the eye was performed prospectively in 20 patients at 1.5 Tesla (7 cm loop surface coil) and 3 Tesla (head coil). These images were analysed qualitatively and quantitatively and statistical significance was tested using the Wilcoxon-signed-rank test (a p-value of less than 0.05 was considered to indicate statistical significance). The analysis of the phantom images yielded the highest mean signal-to-noise ratio (SNR) at 3 Tesla with the use of the 4 cm loop surface coil. In the phantom experiment as well as in the patient studies the SNR was higher at 1.5 Tesla by applying the 7 cm surface coil than at 3 Tesla by applying the head coil. Concerning the delineation of anatomic structures no statistically significant differences were found. Our results show that the influence of small loop surface coils on image quality (expressed in SNR) in ocular MRI is higher than the influence of the magnetic field strength. The similar visibility of detailed anatomy leads to the conclusion that the image quality of ocular MRI at 3 Tesla remains acceptable by applying the head coil as a receiver coil. © Georg Thieme Verlag KG Stuttgart · New York.

  11. Eddy Current Signal Analysis for Transmit-Receive Pancake Coil on ECT Array Probe

    International Nuclear Information System (INIS)

    Lee, Hyang Beom

    2006-01-01

    In this paper, the eddy current signals come from a pair of transmit-receive (T/R) pancake coil on ECT array Probe are analyzed with the variations of the lift-of and of the distance between transmit and receive coils. To obtain the electromagnetic characteristics of the probes, the governing equation describing the eddy current problems is derived from Maxwell's equation and is solved using three-dimensional finite element method. Eddy current signals from T/R coils on ECT array probe have quite different characteristics compared with ones from impedance coil on rotating pancake coil probe. The results in this paper ran be helpful when the field eddy current signals from ECT array probe are evaluated

  12. Effective arrangement of separated transmit-only/receive-only RF coil for improvement of B1 homogeneity at 7 Tesla

    Science.gov (United States)

    Im, Geun Ho; Seo, Jeong-Hoon; Kim, Kyoung-Nam; Heo, Phil; Chung, Julius Juhyun; Jang, Moon-Sun; Lee, Jung Hee; Kim, Jae-Hun; Kim, Sun I.

    2014-09-01

    This article presents an effective arrangement with shifted transmit (Tx)-only and receive (Rx)-only (TORO) radiofrequency (RF) coils in a single-channel surface coil for improving the magnetic flux ( B 1) homogeneity in an ultra-high field (UHF) magnetic resonance imaging (MRI) scanner. The proposed new methodology for the coil arrangement using the shifted TORO RF coils was demonstrated for coils with 50-mm, 100-mm, and 150-mm-square surfaces and the results were compared to those for general Tx/Rx surface coils with the same dimensions. The computational analysis indicated that a homogeneous B1 field was achieved when the Rx-only coil was shifted in the two-dimensional xy-plane away from the Tx-only coils. Because the proposed coil configuration provides a unique opportunity for increasing the B 1 homogeneity, this feature is likely to increase the feasibility via new coil arrangements of UHF surface design and fabrication.

  13. Wirelessly powered electrowetting-on-dielectric (EWOD) by planar receiver coils

    Science.gov (United States)

    Byun, Sang Hyun; Yuan, Junqi; Yoon, Myung Gon; Cho, Sung Kwon

    2015-03-01

    Electrowetting-on-dielectric (EWOD) is one of the most versatile methods used to control the wettability of liquids using electrical input. In most applications, EWOD is applied using physical wiring, which may restrict its application to implantable EWOD devices. In order to resolve this issue, we have studied and developed a wirelessly powered EWOD by using planar coils at the receiver that are fabricated out of a printed circuit board (PCB) by means of standard micro photolithography. Unlike conventional, bulky, spool coil type, the planar coil type lends itself to compact design and easy integration with EWOD chips. The present wireless powering principle is based on magnetic induction, which is very efficient when the transmitter and receiver coils are close to each other. The voltage obtained at the receiver is much higher than typically required EWOD voltages (>50 V) using a high transmission frequency (~MHz). The span of the EWOD contact angle is over 40°. In addition, amplitude modulation (AM) is implemented in the present wireless powering setup, followed by demodulation, in order to oscillate droplets at low frequency. This technique ensures smooth and reliable droplet movements. The wirelessly powered EWOD is used to transport a droplet and is mounted in a mini-boat which it powers and propels.

  14. The effect of receiver coil orientations on the imaging performance of magnetic induction tomography

    Science.gov (United States)

    Gürsoy, D.; Scharfetter, H.

    2009-10-01

    Magnetic induction tomography is an imaging modality which aims to reconstruct the conductivity distribution of the human body. It uses magnetic induction to excite the body and an array of sensor coils to detect the perturbations in the magnetic field. Up to now, much effort has been expended with the aim of finding an efficient coil configuration to extend the dynamic range of the measured signal. However, the merits of different sensor orientations on the imaging performance have not been studied in great detail so far. Therefore, the aim of the study is to fill the void of a systematic investigation of coil orientations on the reconstruction quality of the designs. To this end, a number of alternative receiver array designs with different coil orientations were suggested and the evaluations of the designs were performed based on the singular value decomposition. A generalized class of quality measures, the subclasses of which are linked to both the spatial resolution and uncertainty measures, was used to assess the performance on the radial and axial axes of a cylindrical phantom. The detectability of local conductivity perturbations in the phantom was explored using the reconstructed images. It is possible to draw the conclusion that the proper choice of the coil orientations significantly influences the number of usable singular vectors and accordingly the stability of image reconstruction, although the effect of increased stability on the quality of the reconstructed images was not of paramount importance due to the reduced independent information content of the associated singular vectors.

  15. The effect of receiver coil orientations on the imaging performance of magnetic induction tomography

    International Nuclear Information System (INIS)

    Gürsoy, D; Scharfetter, H

    2009-01-01

    Magnetic induction tomography is an imaging modality which aims to reconstruct the conductivity distribution of the human body. It uses magnetic induction to excite the body and an array of sensor coils to detect the perturbations in the magnetic field. Up to now, much effort has been expended with the aim of finding an efficient coil configuration to extend the dynamic range of the measured signal. However, the merits of different sensor orientations on the imaging performance have not been studied in great detail so far. Therefore, the aim of the study is to fill the void of a systematic investigation of coil orientations on the reconstruction quality of the designs. To this end, a number of alternative receiver array designs with different coil orientations were suggested and the evaluations of the designs were performed based on the singular value decomposition. A generalized class of quality measures, the subclasses of which are linked to both the spatial resolution and uncertainty measures, was used to assess the performance on the radial and axial axes of a cylindrical phantom. The detectability of local conductivity perturbations in the phantom was explored using the reconstructed images. It is possible to draw the conclusion that the proper choice of the coil orientations significantly influences the number of usable singular vectors and accordingly the stability of image reconstruction, although the effect of increased stability on the quality of the reconstructed images was not of paramount importance due to the reduced independent information content of the associated singular vectors

  16. Comparison of a 28 Channel-Receive Array Coil and Quadrature Volume Coil for Morphologic Imaging and T2 Mapping of Knee Cartilage at 7 Tesla

    Science.gov (United States)

    Chang, Gregory; Wiggins, Graham C.; Xia, Ding; Lattanzi, Riccardo; Madelin, Guillaume; Raya, Jose G.; Finnerty, Matthew; Fujita, Hiroyuki; Recht, Michael P.; Regatte, Ravinder R.

    2011-01-01

    Purpose To compare a new birdcage-transmit, 28 channel-receive array (28 Ch) coil and a quadrature volume coil for 7 Tesla morphologic MRI and T2 mapping of knee cartilage. Methods The right knees of ten healthy subjects were imaged on a 7 Tesla whole body MR scanner using both coils. 3-dimensional fast low-angle shot (3D-FLASH) and multi-echo spin-echo (MESE) sequences were implemented. Cartilage signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), thickness, and T2 values were assessed. Results SNR/CNR was 17–400% greater for the 28 Ch compared to the quadrature coil (p≤0.005). Bland-Altman plots show mean differences between measurements of tibial/femoral cartilage thickness and T2 values obtained with each coil to be small (−0.002±0.009 cm/0.003±0.011 cm) and large (−6.8±6.7 ms/−8.2±9.7 ms), respectively. For the 28 Ch coil, when parallel imaging with acceleration factors (AF) 2, 3, and 4 was performed, SNR retained was: 62–69%, 51–55%, and 39–45%. Conclusion A 28 Ch knee coil provides increased SNR/CNR for 7T cartilage morphologic imaging and T2 mapping. Coils should be switched with caution during clinical studies because T2 values may differ. The greater SNR of the 28 Ch coil could be used to perform parallel imaging with AF2 and obtain similar SNR as the quadrature coil. PMID:22095723

  17. High-resolution magnetic resonance imaging of the anal sphincter using a dedicated endoanal receiver coil

    International Nuclear Information System (INIS)

    DeSouza, N.M.; Williams, A.D.; Gilderdale, D.J.

    1999-01-01

    The use of a surface coil in MR imaging improves signal-to-noise ratio of adjacent tissues of interest. We therefore devised an endoanal receiver coil for imaging the anal sphincter. The probe is solid and re-usable: it comprises a saddle geometry receiver with integral tuning, matching and decoupling. It is placed in the anal canal and immobilised externally. Both in vitro and in vivo normal anatomy is identified. The mucosa is high signal intensity, the submucosa low signal intensity, the internal sphincter uniformly high signal intensity and the external sphincter low signal intensity on T1- and T2-weighted images. In females, the transverse perineal muscle bridges the inferior part of the external sphincter anteriorly. In perianal sepsis, collections and the site of the endoanal opening are identified. In early-onset fecal incontinence following obstetric trauma/surgery, focal sphincter defects are demonstrated; in late-onset fecal incontinence external sphincter atrophy is seen. In fecally incontinent patients with scleroderma, forward deviation of the anterior sphincter musculature with descent of rectal air and feces into the anal canal is noted. The extent of sphincter invasion is assessed in low rectal tumours. In children with congenital anorectal anomalies, abnormalities of the muscle components are defined using smaller-diameter coils. Such information is invaluable in the assessment and surgical planning of patients with a variety of anorectal pathologies. (orig.)

  18. High-resolution magnetic resonance imaging of the anal sphincter using a dedicated endoanal receiver coil

    Energy Technology Data Exchange (ETDEWEB)

    DeSouza, N.M.; Williams, A.D.; Gilderdale, D.J. [Dept. of Radiology, Imperial College School of Medicine, London (United Kingdom)

    1999-04-01

    The use of a surface coil in MR imaging improves signal-to-noise ratio of adjacent tissues of interest. We therefore devised an endoanal receiver coil for imaging the anal sphincter. The probe is solid and re-usable: it comprises a saddle geometry receiver with integral tuning, matching and decoupling. It is placed in the anal canal and immobilised externally. Both in vitro and in vivo normal anatomy is identified. The mucosa is high signal intensity, the submucosa low signal intensity, the internal sphincter uniformly high signal intensity and the external sphincter low signal intensity on T1- and T2-weighted images. In females, the transverse perineal muscle bridges the inferior part of the external sphincter anteriorly. In perianal sepsis, collections and the site of the endoanal opening are identified. In early-onset fecal incontinence following obstetric trauma/surgery, focal sphincter defects are demonstrated; in late-onset fecal incontinence external sphincter atrophy is seen. In fecally incontinent patients with scleroderma, forward deviation of the anterior sphincter musculature with descent of rectal air and feces into the anal canal is noted. The extent of sphincter invasion is assessed in low rectal tumours. In children with congenital anorectal anomalies, abnormalities of the muscle components are defined using smaller-diameter coils. Such information is invaluable in the assessment and surgical planning of patients with a variety of anorectal pathologies. (orig.) With 15 figs., 26 refs.

  19. Passive radiofrequency shimming in the thighs at 3 Tesla using high permittivity materials and body coil receive uniformity correction.

    Science.gov (United States)

    Brink, Wyger M; Versluis, Maarten J; Peeters, Johannes M; Börnert, Peter; Webb, Andrew G

    2016-12-01

    To explore the effects of high permittivity dielectric pads on the transmit and receive characteristics of a 3 Tesla body coil centered at the thighs, and their implications on image uniformity in receive array applications. Transmit and receive profiles of the body coil with and without dielectric pads were simulated and measured in healthy volunteers. Parallel imaging was performed using sensitivity encoding (SENSE) with and without pads. An intensity correction filter was constructed from the measured receive profile of the body coil. Measured and simulated data show that the dielectric pads improve the transmit homogeneity of the body coil in the thighs, but decrease its receive homogeneity, which propagates into reconstruction algorithms in which the body coil is used as a reference. However, by correcting for the body coil reception profile this effect can be mitigated. Combining high permittivity dielectric pads with an appropriate body coil receive sensitivity filter improves the image uniformity substantially compared with the situation without pads. Magn Reson Med 76:1951-1956, 2016. © 2015 International Society for Magnetic Resonance in Medicine. © 2015 International Society for Magnetic Resonance in Medicine.

  20. Three-phase receiving coil of wireless power transmission system for gastrointestinal robot

    Science.gov (United States)

    Jia, Z. W.; Jiang, T.; Liu, Y.

    2017-11-01

    Power shortage is the bottleneck for the wide application of gastrointestinal (GI) robot. Owing to the limited volume and free change of orientation of the receiving set in GI trace, the optimal of receiving set is the key point to promote the transmission efficiency of wireless power transmission system. A new type of receiving set, similar to the winding of three-phase asynchronous motor, is presented and compared with the original three-dimensional orthogonal coil. Considering the given volume and the space utilization ratio, the three-phase and the three-orthogonal ones are the parameters which are optimized and compared. Both the transmission efficiency and stability are analyzed and verified by in vitro experiments. Animal experiments show that the new one could provide at least 420 mW power in volume of Φ11 × 13mm with a uniformity of 78.3% for the GI robot.

  1. A 16-channel receive, forced current excitation dual-transmit coil for breast imaging at 7T.

    Directory of Open Access Journals (Sweden)

    Samantha By

    Full Text Available To enable high spatial and temporal breast imaging resolution via combined use of high field MRI, array coils, and forced current excitation (FCE multi channel transmit.A unilateral 16-channel receive array insert was designed for use in a transmit volume coil optimized for quadrature operation with dual-transmit RF shimming at 7 T. Signal-to-noise ratio (SNR maps, g-factor maps, and high spatial and temporal resolution in vivo images were acquired to demonstrate the utility of the coil architecture.The dual-transmit FCE coil provided homogeneous excitation and the array provided an increase in average SNR of 3.3 times (max 10.8, min 1.5 compared to the volume coil in transmit/receive mode. High resolution accelerated in vivo breast imaging demonstrated the ability to achieve isotropic spatial resolution of 0.5 mm within clinically relevant 90 s scan times, as well as the ability to perform 1.0 mm isotropic resolution imaging, 7 s per dynamics, with the use of bidirectional SENSE acceleration of up to R = 9.The FCE design of the transmit coil easily accommodates the addition of a sixteen channel array coil. The improved spatial and temporal resolution provided by the high-field array coil with FCE dual-channel transmit will ultimately be beneficial in lesion detection and characterization.

  2. Modeling of coupling mechanism of wireless power transfer system and vibration phenomenon of receiver-coil in three-coil system

    Directory of Open Access Journals (Sweden)

    Suqi Liu

    2017-11-01

    Full Text Available Wireless power transfer (WPT via coupled magnetic resonances has become a focus recently, but the mechanisms responsible for such work are uncertain. We found that WPT system is a self-organization system by utilizing self-organization theory to judge. Firstly, the circuit model was established and transfer characteristic of a system was researched by utilizing circuit theories. Thus, with the introduction of entropy variable S, the energy equation of state can be established from the energy of the transmitter side and the energy of the receiver side. According to the energy equation of state, this paper obtains two equations when the reactance of the transmitter side and the receiver side equate to zero respectively. The vibration phenomenon of the receiver-coil in a three-coil WPT system was predicted and explained. Our findings illuminate the unusual self-organization in the WPT system and explain the vibration phenomenon of the receiver-coil in a three-coil WPT system.

  3. Modeling of coupling mechanism of wireless power transfer system and vibration phenomenon of receiver-coil in three-coil system

    Science.gov (United States)

    Liu, Suqi; Tan, Jianping; Wen, Xue

    2017-11-01

    Wireless power transfer (WPT) via coupled magnetic resonances has become a focus recently, but the mechanisms responsible for such work are uncertain. We found that WPT system is a self-organization system by utilizing self-organization theory to judge. Firstly, the circuit model was established and transfer characteristic of a system was researched by utilizing circuit theories. Thus, with the introduction of entropy variable S, the energy equation of state can be established from the energy of the transmitter side and the energy of the receiver side. According to the energy equation of state, this paper obtains two equations when the reactance of the transmitter side and the receiver side equate to zero respectively. The vibration phenomenon of the receiver-coil in a three-coil WPT system was predicted and explained. Our findings illuminate the unusual self-organization in the WPT system and explain the vibration phenomenon of the receiver-coil in a three-coil WPT system.

  4. A Correlating Receiver for OFDM at Low SNR

    NARCIS (Netherlands)

    Kokkeler, Andre B.J.; Smit, Gerardus Johannes Maria

    By extending OFDM symbols, acceptable BER performance can be achieved at low SNRs. Two alternative differential receiver architectures are presented, a receiver based on a FX correlator (Fourier transformation before correlation) and based on an XF correlator (correlation before Fourier

  5. Novel 16-channel receive coil array for accelerated upper airway MRI at 3 Tesla.

    Science.gov (United States)

    Kim, Yoon-Chul; Hayes, Cecil E; Narayanan, Shrikanth S; Nayak, Krishna S

    2011-06-01

    Upper airway MRI can provide a noninvasive assessment of speech and swallowing disorders and sleep apnea. Recent work has demonstrated the value of high-resolution three-dimensional imaging and dynamic two-dimensional imaging and the importance of further improvements in spatio-temporal resolution. The purpose of the study was to describe a novel 16-channel 3 Tesla receive coil that is highly sensitive to the human upper airway and investigate the performance of accelerated upper airway MRI with the coil. In three-dimensional imaging of the upper airway during static posture, 6-fold acceleration is demonstrated using parallel imaging, potentially leading to capturing a whole three-dimensional vocal tract with 1.25 mm isotropic resolution within 9 sec of sustained sound production. Midsagittal spiral parallel imaging of vocal tract dynamics during natural speech production is demonstrated with 2 × 2 mm(2) in-plane spatial and 84 ms temporal resolution. Copyright © 2010 Wiley-Liss, Inc.

  6. Comparison of endorectal coil and nonendorectal coil T2W and diffusion-weighted MRI at 3 Tesla for localizing prostate cancer: correlation with whole-mount histopathology.

    Science.gov (United States)

    Turkbey, Baris; Merino, Maria J; Gallardo, Elma Carvajal; Shah, Vijay; Aras, Omer; Bernardo, Marcelino; Mena, Esther; Daar, Dagane; Rastinehad, Ardeshir R; Linehan, W Marston; Wood, Bradford J; Pinto, Peter A; Choyke, Peter L

    2014-06-01

    To compare utility of T2-weighted (T2W) MRI and diffusion-weighted MRI (DWI-MRI) obtained with and without an endorectal coil at 3 Tesla (T) for localizing prostate cancer. This Institutional Review Board-approved study included 20 patients (median prostate-specific antigen, 8.4 ng/mL). Patients underwent consecutive prostate MRIs at 3T, first with a surface coil alone, then with combination of surface, endorectal coils (dual coil) followed by robotic assisted radical prostatectomy. Lesions were mapped at time of acquisition on dual-coil T2W, DWI-MRI. To avoid bias, 6 months later nonendorectal coil T2W, DWI-MRI were mapped. Both MRI evaluations were performed by two readers blinded to pathology with differences resolved by consensus. A lesion-based correlation with whole-mount histopathology was performed. At histopathology 51 cancer foci were present ranging in size from 2 to 60 mm. The sensitivity of the endorectal dual-coil, nonendorectal coil MRIs were 0.76, 0.45, respectively. PPVs for endorectal dual-coil, nonendorectal coil MRI were 0.80, 0.64, respectively. Mean size of detected lesions with nonendorectal coil MRI were larger than those detected by dual-coil MRI (22 mm versus 17.4 mm). Dual-coil prostate MRI detected more cancer foci than nonendorectal coil MRI. While nonendorectal coil MRI is an attractive alternative, physicians performing prostate MRI should be aware of its limitations. Copyright © 2013 Wiley Periodicals, Inc.

  7. A Fully Integrated Dual-Channel On-Coil CMOS Receiver for Array Coils in 1.5-10.5 T MRI.

    Science.gov (United States)

    Sporrer, Benjamin; Wu, Lianbo; Bettini, Luca; Vogt, Christian; Reber, Jonas; Marjanovic, Josip; Burger, Thomas; Brunner, David O; Pruessmann, Klaas P; Troster, Gerhard; Huang, Qiuting

    2017-12-01

    Magnetic resonance imaging (MRI) is among the most important medical imaging modalities. Coil arrays and receivers with high channel counts (16 and more) have to be deployed to obtain the image quality and acquisition speed required by modern clinical protocols. In this paper, we report the theoretical analysis, the system-level design, and the circuit implementation of the first receiver IC (RXIC) for clinical MRI fully integrated in a modern CMOS technology. The dual-channel RXIC sits directly on the sensor coil, thus eliminating any RF cable otherwise required to transport the information out of the magnetic field. The first stage LNA was implemented using a noise-canceling architecture providing a highly reflective input used to decouple the individual channels of the array. Digitization is performed directly on-chip at base-band by means of a delta-sigma modulator, allowing the subsequent optical transmission of data. The presented receiver, implemented in a CMOS technology, is compatible with MRI scanners up to . It reaches sub- noise figure for MRI units and features a dynamic range up to at a power consumption below per channel, with an area occupation of . Mounted on a small-sized printed circuit board (PCB), the receiver IC has been employed in a commercial MRI scanner to acquire in-vivo images matching the quality of traditional systems, demonstrating the first step toward multichannel wearable MRI array coils.

  8. Empirical Correlation of the Morphology of Coiled Carbon Nano tubes with Their Response to Axial Compression

    International Nuclear Information System (INIS)

    Barber, J.R.; Boyles, J.S.; Bottomley, L.A.; Ferri, A.A.

    2014-01-01

    The mechanical response of thirteen different helical multi-walled carbon nano coils to axial compression is reported. Each nano coil was attached to the apex of a cantilever probe tip; its dimensions and orientation relative to the tip apex were determined with scanning electron microscopy. The atomic force microscope was employed to apply a cyclic axial load on the nano coil. Its mechanical response was determined by simultaneous collection of the thermal resonance frequency, displacement, and oscillation amplitude of the cantilever-nano tube system in real time. Depending upon compression parameters, each coil underwent buckling, bending, and slip-stick motion. Characteristic features in the thermal resonance spectrum and in the force and oscillation amplitude curves for each of these responses to induced stress are presented. Following compression studies, the structure and morphology of each nano coil were determined by transmission electron microscopy. The compression stiffness of each nano coil was estimated from the resonant frequency of the cantilever at the point of contact with the substrate surface. From this value, the elastic modulus of the nano coil was computed and correlated with the coiled carbon nano tube’s morphology.

  9. THE CORRELATED TRACK RECEIVER OF TONE TRACK CIRCUITS

    Directory of Open Access Journals (Sweden)

    K. V. Goncharov

    2011-05-01

    Full Text Available The work is devoted to further improvement of processing algorithm of checking signals of rail line. The simulation modeling of correlation track receiver of tone rail circuits has been executed; the benchmark analysis of correlation receiver and direct amplifier receiver has been executed.

  10. 32-channel 3 Tesla receive-only phased-array head coil with soccer-ball element geometry.

    Science.gov (United States)

    Wiggins, G C; Triantafyllou, C; Potthast, A; Reykowski, A; Nittka, M; Wald, L L

    2006-07-01

    A 32-channel 3T receive-only phased-array head coil was developed for human brain imaging. The helmet-shaped array was designed to closely fit the head with individual overlapping circular elements arranged in patterns of hexagonal and pentagonal symmetry similar to that of a soccer ball. The signal-to-noise ratio (SNR) and noise amplification (g-factor) in accelerated imaging applications were quantitatively evaluated in phantom and human images and compared with commercially available head coils. The 32-channel coil showed SNR gains of up to 3.5-fold in the cortex and 1.4-fold in the corpus callosum compared to a (larger) commercial eight-channel head coil. The experimentally measured g-factor performance of the helmet array showed significant improvement compared to the eight-channel array (peak g-factor 59% and 26% of the eight-channel values for four- and fivefold acceleration). The performance of the arrays is demonstrated in high-resolution and highly accelerated brain images. Copyright (c) 2006 Wiley-Liss, Inc.

  11. Characterization and evaluation of a flexible MRI receive coil array for radiation therapy MR treatment planning using highly decoupled RF circuits

    Science.gov (United States)

    McGee, Kiaran P.; Stormont, Robert S.; Lindsay, Scott A.; Taracila, Victor; Savitskij, Dennis; Robb, Fraser; Witte, Robert J.; Kaufmann, Timothy J.; Huston, John, III; Riederer, Stephen J.; Borisch, Eric A.; Rossman, Phillip J.

    2018-04-01

    The growth in the use of magnetic resonance imaging (MRI) data for radiation therapy (RT) treatment planning has been facilitated by scanner hardware and software advances that have enabled RT patients to be imaged in treatment position while providing morphologic and functional assessment of tumor volumes and surrounding normal tissues. Despite these advances, manufacturers have been slow to develop radiofrequency (RF) coils that closely follow the contour of a RT patient undergoing MR imaging. Instead, relatively large form surface coil arrays have been adapted from diagnostic imaging. These arrays can be challenging to place on, and in general do not conform to the patient’s body habitus, resulting in sub optimal image quality. The purpose of this study is to report on the characterization of a new flexible and highly decoupled RF coil for use in MR imaging of RT patients. Coil performance was evaluated by performing signal-to-noise ratio (SNR) and noise correlation measurements using two coil (SNR) and four coil (noise correlation) element combinations as a function of coil overlap distance and comparing these values to those obtained using conventional coil elements. In vivo testing was performed in both normal volunteers and patients using a four and 16 element RF coil. Phantom experiments demonstrate the highly decoupled nature of the new coil elements when compared to conventional RF coils, while in vivo testing demonstrate that these coils can be integrated into extremely flexible and form fitting substrates that follow the exact contour of the patient. The new coil design addresses limitations imposed by traditional surface coil arrays and have the potential to significantly impact MR imaging for both diagnostic and RT applications.

  12. Impact of endobronchial coiling on segmental bronchial lumen in treated and untreated lung lobes: Correlation with changes in lung volume, clinical and pulmonary function tests.

    Science.gov (United States)

    Kloth, C; Thaiss, W M; Hetzel, J; Ditt, H; Grosse, U; Nikolaou, K; Horger, M

    2016-07-01

    To assess the impact of endobronchial coiling on the segment bronchus cross-sectional area and volumes in patients with lung emphysema using quantitative chest-CT measurements. Thirty patients (female = 15; median age = 65.36 years) received chest-CT before and after endobronchial coiling for lung volume reduction (LVR) between January 2010 and December 2014. Thin-slice (0.6 mm) non-enhanced image data sets were acquired both at end-inspiration and end-expiration using helical technique and 120 kV/100-150 mAs. Clinical response was defined as an increase in the walking distance (Six-minute walk test; 6MWT) after LVR-therapy. Additionally, pulmonary function test (PFT) measurements were used for clinical correlation. In the treated segmental bronchia, the cross-sectional lumen area showed significant reduction (p  0.05). In the ipsilateral lobes, the lumina showed no significant changes. In the contralateral lung, we found tendency towards increased cross-sectional area in inspiration (p = 0.06). Volumes of the treated segments correlated with the treated segmental bronchial lumina in expiration (r = 0.80, p volume of the treated lobe in responders only. Endobronchial coiling causes significant decrease in the cross-sectional area of treated segment bronchi in inspiration and a slight increase in expiration accompanied by a volume reduction. • Endobronchial coiling has indirect impact on cross-sectional area of treated segment bronchi • Volume changes of treated lobes correlate with changes in bronchial cross-sectional area • Coil-induced effects reflect their stabilizing and stiffening impact on lung parenchyma • Endobronchial coiling reduces bronchial collapsing compensating the loss of elasticity.

  13. An 8-channel transceiver 7-channel receive RF coil setup for high SNR ultrahigh-field MRI of the shoulder at 7T.

    Science.gov (United States)

    Rietsch, Stefan H G; Pfaffenrot, Viktor; Bitz, Andreas K; Orzada, Stephan; Brunheim, Sascha; Lazik-Palm, Andrea; Theysohn, Jens M; Ladd, Mark E; Quick, Harald H; Kraff, Oliver

    2017-12-01

    In this work, we present an 8-channel transceiver (Tx/Rx) 7-channel receive (Rx) radiofrequency (RF) coil setup for 7 T ultrahigh-field MR imaging of the shoulder. A C-shaped 8-channel Tx/Rx coil was combined with an anatomically close-fitting 7-channel Rx-only coil. The safety and performance parameters of this coil setup were evaluated on the bench and in phantom experiments. The 7 T MR imaging performance of the shoulder RF coil setup was evaluated in in vivo measurements using a 3D DESS, a 2D PD-weighted TSE sequence, and safety supervision based on virtual observation points. Distinct SNR gain and acceleration capabilities provided by the additional 7-channel Rx-only coil were demonstrated in phantom and in vivo measurements. The power efficiency indicated good performance of each channel and a maximum B 1 + of 19 μT if the hardware RF power limits of the MR system were exploited. MR imaging of the shoulder was demonstrated with clinically excellent image quality and submillimeter spatial resolution. The presented 8-channel transceiver 7-channel receive RF coil setup was successfully applied for in vivo 7 T MRI of the shoulder providing a clear SNR gain vs the transceiver array without the additional receive array. Homogeneous images across the shoulder region were obtained using 8-channel subject-specific phase-only RF shimming. © 2017 American Association of Physicists in Medicine.

  14. An Analog Correlator for Ultra-Wideband Receivers

    Directory of Open Access Journals (Sweden)

    Tu Chunjiang

    2005-01-01

    Full Text Available We present a new analog circuit exhibiting high bandwidth and low distortion, specially designed for signal correlation in an ultra-wideband receiver front end. The ultra-wideband short impulse signals are correlated with a local pulse template by the correlator. A comparator then samples the output for signal detection. A typical Gilbert mixer core is adopted for multiplication of broadband signals up to . As a result of synchronization of the received signal and the local template, the output voltage level after integration and sampling can reach up to , which is sufficient for detection by the comparator. The circuit dissipates about from double voltage supplies of and using SiGe BiCMOS technology. Simulation results are presented to show the feasibility of this circuit design for use in ultra-wideband receivers.

  15. Using a whole-body 31P birdcage transmit coil and 16-element receive array for human cardiac metabolic imaging at 7T.

    Directory of Open Access Journals (Sweden)

    Ladislav Valkovič

    Full Text Available Cardiac phosphorus magnetic resonance spectroscopy (31P-MRS provides unique insight into the mechanisms of heart failure. Yet, clinical applications have been hindered by the restricted sensitivity of the surface radiofrequency-coils normally used. These permit the analysis of spectra only from the interventricular septum, or large volumes of myocardium, which may not be meaningful in focal disease. Löring et al. recently presented a prototype whole-body (52 cm diameter transmit/receive birdcage coil for 31P at 7T. We now present a new, easily-removable, whole-body 31P transmit radiofrequency-coil built into a patient-bed extension combined with a 16-element receive array for cardiac 31P-MRS.A fully-removable (55 cm diameter birdcage transmit coil was combined with a 16-element receive array on a Magnetom 7T scanner (Siemens, Germany. Electro-magnetic field simulations and phantom tests of the setup were performed. In vivo maps of B1+, metabolite signals, and saturation-band efficiency were acquired across the torsos of eight volunteers.The combined (volume-transmit, local receive array setup increased signal-to-noise ratio 2.6-fold 10 cm below the array (depth of the interventricular septum compared to using the birdcage coil in transceiver mode. The simulated coefficient of variation for B1+ of the whole-body coil across the heart was 46.7% (surface coil 129.0%; and the in vivo measured value was 38.4%. Metabolite images of 2,3-diphosphoglycerate clearly resolved the ventricular blood pools, and muscle tissue was visible in phosphocreatine (PCr maps. Amplitude-modulated saturation bands achieved 71±4% suppression of phosphocreatine PCr in chest-wall muscles. Subjects reported they were comfortable.This easy-to-assemble, volume-transmit, local receive array coil combination significantly improves the homogeneity and field-of-view for metabolic imaging of the human heart at 7T.

  16. A Two-dimensional Sixteen Channel Transmit/Receive Coil Array for Cardiac MRI at 7.0 Tesla: Design, Evaluation and Application

    Science.gov (United States)

    Thalhammer, Christof; Renz, Wolfgang; Winter, Lukas; Hezel, Fabian; Rieger, Jan; Pfeiffer, Harald; Graessl, Andreas; Seifert, Frank; Hoffmann, Werner; von Knobelsdorff-Brenkenhoff, Florian; Tkachenko, Valeriy; Schulz-Menger, Jeanette; Kellman, Peter; Niendorf, Thoralf

    2012-01-01

    Purpose To design, evaluate and apply a two-dimensional 16 channel transmit/receive coil array tailored for cardiac MRI at 7.0 Tesla. Material and Methods The cardiac coil array consists of 2 sections each using 8 elements arranged in a 2 × 4 array. RF safety was validated by SAR simulations. Cardiac imaging was performed using 2D CINE FLASH imaging, T2* mapping and fat-water separation imaging. The characteristics of the coil array were analyzed including parallel imaging performance, left ventricular chamber quantification and overall image quality. Results RF characteristics were found to be appropriate for all subjects included in the study. The SAR values derived from the simulations fall well in the limits of legal guidelines. The baseline SNR advantage at 7.0 T was put to use to acquire 2D CINE images of the heart with a very high spatial resolution of (1 × 1 × 4) mm3. The proposed coil array supports 1D acceleration factors of up to R=4 without impairing image quality significantly. Conclusions The 16 channel TX/RX coil has the capability to acquire high contrast and high spatial resolution images of the heart at 7.0 Tesla. PMID:22706727

  17. Cardiac MRI in mice at 9.4 Tesla with a transmit-receive surface coil and a cardiac-tailored intensity-correction algorithm.

    Science.gov (United States)

    Sosnovik, David E; Dai, Guangping; Nahrendorf, Matthias; Rosen, Bruce R; Seethamraju, Ravi

    2007-08-01

    To evaluate the use of a transmit-receive surface (TRS) coil and a cardiac-tailored intensity-correction algorithm for cardiac MRI in mice at 9.4 Tesla (9.4T). Fast low-angle shot (FLASH) cines, with and without delays alternating with nutations for tailored excitation (DANTE) tagging, were acquired in 13 mice. An intensity-correction algorithm was developed to compensate for the sensitivity profile of the surface coil, and was tailored to account for the unique distribution of noise and flow artifacts in cardiac MR images. Image quality was extremely high and allowed fine structures such as trabeculations, valve cusps, and coronary arteries to be clearly visualized. The tag lines created with the surface coil were also sharp and clearly visible. Application of the intensity-correction algorithm improved signal intensity, tissue contrast, and image quality even further. Importantly, the cardiac-tailored properties of the correction algorithm prevented noise and flow artifacts from being significantly amplified. The feasibility and value of cardiac MRI in mice with a TRS coil has been demonstrated. In addition, a cardiac-tailored intensity-correction algorithm has been developed and shown to improve image quality even further. The use of these techniques could produce significant potential benefits over a broad range of scanners, coil configurations, and field strengths. (c) 2007 Wiley-Liss, Inc.

  18. RF safety assessment of a bilateral four-channel transmit/receive 7 Tesla breast coil: SAR versus tissue temperature limits.

    Science.gov (United States)

    Fiedler, Thomas M; Ladd, Mark E; Bitz, Andreas K

    2017-01-01

    The purpose of this work was to perform an RF safety evaluation for a bilateral four-channel transmit/receive breast coil and to determine the maximum permissible input power for which RF exposure of the subject stays within recommended limits. The safety evaluation was done based on SAR as well as on temperature simulations. In comparison to SAR, temperature is more directly correlated with tissue damage, which allows a more precise safety assessment. The temperature simulations were performed by applying three different blood perfusion models as well as two different ambient temperatures. The goal was to evaluate whether the SAR and temperature distributions correlate inside the human body and whether SAR or temperature is more conservative with respect to the limits specified by the IEC. A simulation model was constructed including coil housing and MR environment. Lumped elements and feed networks were modeled by a network co-simulation. The model was validated by comparison of S-parameters and B 1 + maps obtained in an anatomical phantom. Three numerical body models were generated based on 3 Tesla MRI images to conform to the coil housing. SAR calculations were performed and the maximal permissible input power was calculated based on IEC guidelines. Temperature simulations were performed based on the Pennes bioheat equation with the power absorption from the RF simulations as heat source. The blood perfusion was modeled as constant to reflect impaired patients as well as with a linear and exponential temperature-dependent increase to reflect two possible models for healthy subjects. Two ambient temperatures were considered to account for cooling effects from the environment. The simulation model was validated with a mean deviation of 3% between measurement and simulation results. The highest 10 g-averaged SAR was found in lung and muscle tissue on the right side of the upper torso. The maximum permissible input power was calculated to be 17 W. The

  19. A 4-channel 3 Tesla phased array receive coil for awake rhesus monkey fMRI and diffusion MRI experiments.

    Science.gov (United States)

    Khachaturian, Mark Haig

    2010-01-01

    Awake monkey fMRI and diffusion MRI combined with conventional neuroscience techniques has the potential to study the structural and functional neural network. The majority of monkey fMRI and diffusion MRI experiments are performed with single coils which suffer from severe EPI distortions which limit resolution. By constructing phased array coils for monkey MRI studies, gains in SNR and anatomical accuracy (i.e., reduction of EPI distortions) can be achieved using parallel imaging. The major challenges associated with constructing phased array coils for monkeys are the variation in head size and space constraints. Here, we apply phased array technology to a 4-channel phased array coil capable of improving the resolution and image quality of full brain awake monkey fMRI and diffusion MRI experiments. The phased array coil is that can adapt to different rhesus monkey head sizes (ages 4-8) and fits in the limited space provided by monkey stereotactic equipment and provides SNR gains in primary visual cortex and anatomical accuracy in conjunction with parallel imaging and improves resolution in fMRI experiments by a factor of 2 (1.25 mm to 1.0 mm isotropic) and diffusion MRI experiments by a factor of 4 (1.5 mm to 0.9 mm isotropic).

  20. Amplitude correlation analysis of W7-AS Mirnov-coil array data and other transport relevant diagnostics

    International Nuclear Information System (INIS)

    Pokol, G.; Por, G.; Zoletnik, S.; Basse, N.P.

    2005-01-01

    This work is based on the amplitude correlation analysis of the signals from a poloidal Mirnov-coil array on the Wendelstein 7 - Advanced Stellarator (W7-AS). The motivation behind this work is an earlier finding, that changes in the RMS amplitude of Mirnov-coil signals are correlated with the amplitude of small scale density turbulence measured by CO2 Laser Scattering. Based on this and other measurements, the hypothesis was set, that some of the magnetic fluctuations are caused by transient MHD modes excited by large turbulent structures. The statistical dependencies between the power modulations of different eigenmodes can provide information about the statistics of these structures. Our amplitude correlation method is based on linear continuous time-frequency representations of the signal, we use Short-Time Fourier Transformation (STFT) with Gabor-atoms to map the signal onto the time-frequency plane, as two dimensional power density distributions. From these transforms we can recover the power modulation of different frequency bands. Provided the selection of the resolution of the transforms and the limits of the frequency bands were correct, the time series calculated this way resembles the original power fluctuation of the selected eigenmode. The only distortion introduced is a convolution smoothing by the time-window used in the transformation. Detailed correlation analysis between different bandpowers of the Mirnov-coil array signals were carried out and presented in bad and good confinement states. In order to reveal the true structure and cause of magnetic fluctuations Mirnov-coil diagnostic signals were also compared with Lithium beam and CO2 Laser Scattering measurements. In our analysis we have found, that there was a strong and systematic difference in the cross-correlations of power bands between different confinement states. (author)

  1. A Correlation Study between Geometry of Collared Coils and Normal Quadrupole Multipole in the Main LHC Dipoles

    CERN Document Server

    Bertinelli, F; Berthollon-Vitte, S; Glaude, D; Vanenkov, I

    2006-01-01

    The quality control implemented at all LHC dipole assemblers includes precise mechanical measurements of the geometry of collared coils. A cross-analysis performed between mechanical and magnetic measurements data shows a correlation between collared coils outer dimensions and the normal quadrupole multipole (b2) for one dipole assembler. The profile geometry of the single collars - as determined from 3D measurements at the collar suppliers and CERN - could not account alone for the significant left – right aperture asymmetry observed. This triggered a deeper investigation on different elements of the geometry of single collars. The results of this work show that the relative positioning of the collaring holes, allowing a small bending deformation of collars under the effect of coil pre-stress, is an important effect that generates a b2 multipole at the limit of specification. The study has deepened the understanding of the factors affecting collared coil geometry and field quality. The precision of 3D m...

  2. A transmit/receive radiofrequency array for imaging the carotid arteries at 7 Tesla: coil design and first in vivo results.

    Science.gov (United States)

    Kraff, Oliver; Bitz, Andreas K; Breyer, Tobias; Kruszona, Stefan; Maderwald, Stefan; Brote, Irina; Gizewski, Elke R; Ladd, Mark E; Quick, Harald H

    2011-04-01

    To develop a transmit/receive radiofrequency (RF) array for magnetic resonance imaging (MRI) of the carotid arteries at 7 T. The prototype is characterized in numerical simulations and bench measurements, and the feasibility of plaque imaging at 7 T is demonstrated in first in vivo images. The RF phased array coil consists of 8 surface loop coils. To allow imaging of both sides of the neck, the RF array is divided into 2 coil clusters, each with 4 overlapping loop elements. For safety validation, numerical computations of the RF field distribution and the corresponding specific absorption rate were performed on the basis of a heterogeneous human body model. To validate the coil model, maps of the transmit B1(+) field were compared between simulation and measurement. In vivo images of a healthy volunteer and a patient (ulcerating plaque and a 50% stenosis of the right internal carotid artery) were acquired using a 3-dimensional FLASH sequence with a high isotropic spatial resolution of 0.54 mm as well as using pulse-triggered proton density (PD)/T2-weighted turbo spin echo sequences. Measurements of the S-parameters yielded a reflection and isolation of the coil elements of better than -18 and -13 dB, respectively. Measurements of the g-factor indicated good image quality for parallel imaging acceleration factors up to 2.4. A similar distribution and a very good match of the absolute values were found between the measured and simulated B1(+) transmit RF field for the validation of the coil model. In vivo images revealed good signal excitation of both sides of the neck and a high vessel-to-background image contrast for the noncontrast-enhanced 3-dimensional FLASH sequence. Imaging at 7 T could depict the extent of stenosis, and revealed the disruption and ulcer of the plaque. This study demonstrates that 2 four-channel transmit/receive RF arrays for each side of the neck is a suitable concept for in vivo MRI of the carotid arteries at 7 Tesla. Further studies are

  3. Estimating achievable signal-to-noise ratios of MRI transmit-receive coils from radiofrequency power measurements: applications in quality control

    International Nuclear Information System (INIS)

    Redpath, T.W.

    2000-01-01

    The inverse relationship between the radiofrequency (RF) power needed to transmit a 90 deg. RF pulse, and the signal-to-noise ratio (SNR) available from a transmit-receive RF coil is well known. The theory is restated and a formula given for the signal-to-noise ratio from water, achievable from a single-shot MRI experiment, in terms of the net forward RF power needed for a rectangular 90 deg. RF pulse of known shape and duration. The result is normalized to a signal bandwidth of 1 Hz and a sample mass of 1 g. The RF power information needed is available on most commercial scanners, as it is used to calculate specific absorption rates for RF tissue heating. The achievable SNR figure will normally be larger that that actually observed, mainly because of receiver noise, but also because of inaccuracies in setting RF pulse angles, and relaxation effects. Phantom experiments were performed on the transmit-receive RF head coil of a commercial MRI system at 0.95 T using a projection method. The measured SNR agreed with that expected from the formula for achievable SNR once a correction was made for the noise figure of the receiving chain. Comparisons of measured SNR figures with those calculated from RF power measurements are expected to be of value in acceptance testing and quality control. (author)

  4. Unshielded asymmetric transmit-only and endorectal receive-only radiofrequency coil for (23) Na MRI of the prostate at 3 tesla.

    Science.gov (United States)

    Farag, Adam; Peterson, Justin Charles; Szekeres, Trevor; Bauman, Glenn; Chin, Joseph; Romagnoli, Cesare; Bartha, Robert; Scholl, Timothy J

    2015-08-01

    To develop and optimize radiofrequency (RF) hardware for the detection of endogenous sodium ((23) Na) by 3.0 Tesla (T) MRI in the human prostate. A transmit-only receive-only (TORO) RF system of resonators consisting of an unshielded, asymmetric, quadrature birdcage (transmit), and an endorectal (ER), linear, surface (receive) coil were developed and tested on a 3T MRI scanner. Two different ER receivers were constructed; a single-tuned ((23) Na) and a dual-tuned ((1) H/(23) Na). Both receivers were evaluated by the measurements of signal-to-noise ratio (SNR) and B1 homogeneity. For tissue sodium concentration (TSC) quantification, vials containing known sodium concentrations were incorporated into the ER. The system was used to measure the prostate TSC of three men (age 55 ± 5 years) with biopsy-proven prostate cancer. B1 field inhomogeneity of the asymmetric transmitter was estimated to be less than 5%. The mean SNR measured in a region of interest within the prostate using the single-tuned ER coil was 54.0 ± 4.6. The mean TSC in the central gland was 60.2 ± 5.7 mmol/L and in the peripheral gland was 70.5 ± 9.0 mmol/L. A TORO system was developed and optimized for (23) Na MRI of the human prostate which showed good sensitivity throughout the prostate for quantitative measurement of TSC. © 2014 Wiley Periodicals, Inc.

  5. Signal-to-noise ratio and MR tissue parameters in human brain imaging at 3, 7, and 9.4 tesla using current receive coil arrays.

    Science.gov (United States)

    Pohmann, Rolf; Speck, Oliver; Scheffler, Klaus

    2016-02-01

    Relaxation times, transmit homogeneity, signal-to-noise ratio (SNR) and parallel imaging g-factor were determined in the human brain at 3T, 7T, and 9.4T, using standard, tight-fitting coil arrays. The same human subjects were scanned at all three field strengths, using identical sequence parameters and similar 31- or 32-channel receive coil arrays. The SNR of three-dimensional (3D) gradient echo images was determined using a multiple replica approach and corrected with measured flip angle and T2 (*) distributions and the T1 of white matter to obtain the intrinsic SNR. The g-factor maps were derived from 3D gradient echo images with several GRAPPA accelerations. As expected, T1 values increased, T2 (*) decreased and the B1 -homogeneity deteriorated with increasing field. The SNR showed a distinctly supralinear increase with field strength by a factor of 3.10 ± 0.20 from 3T to 7T, and 1.76 ± 0.13 from 7T to 9.4T over the entire cerebrum. The g-factors did not show the expected decrease, indicating a dominating role of coil design. In standard experimental conditions, SNR increased supralinearly with field strength (SNR ∼ B0 (1.65) ). To take full advantage of this gain, the deteriorating B1 -homogeneity and the decreasing T2 (*) have to be overcome. © 2015 Wiley Periodicals, Inc.

  6. Molecular basis of coiled-coil oligomerization-state specificity.

    Science.gov (United States)

    Ciani, Barbara; Bjelic, Saša; Honnappa, Srinivas; Jawhari, Hatim; Jaussi, Rolf; Payapilly, Aishwarya; Jowitt, Thomas; Steinmetz, Michel O; Kammerer, Richard A

    2010-11-16

    Coiled coils are extensively and successfully used nowadays to rationally design multistranded structures for applications, including basic research, biotechnology, nanotechnology, materials science, and medicine. The wide range of applications as well as the important functions these structures play in almost all biological processes highlight the need for a detailed understanding of the factors that control coiled-coil folding and oligomerization. Here, we address the important and unresolved question why the presence of particular oligomerization-state determinants within a coiled coil does frequently not correlate with its topology. We found an unexpected, general link between coiled-coil oligomerization-state specificity and trigger sequences, elements that are indispensable for coiled-coil formation. By using the archetype coiled-coil domain of the yeast transcriptional activator GCN4 as a model system, we show that well-established trimer-specific oligomerization-state determinants switch the peptide's topology from a dimer to a trimer only when inserted into the trigger sequence. We successfully confirmed our results in two other, unrelated coiled-coil dimers, ATF1 and cortexillin-1. We furthermore show that multiple topology determinants can coexist in the same trigger sequence, revealing a delicate balance of the resulting oligomerization state by position-dependent forces. Our experimental results should significantly improve the prediction of the oligomerization state of coiled coils. They therefore should have major implications for the rational design of coiled coils and consequently many applications using these popular oligomerization domains.

  7. T1 weighted brain images at 7 Tesla unbiased for Proton Density, T2* contrast and RF coil receive B1 sensitivity with simultaneous vessel visualization.

    Science.gov (United States)

    Van de Moortele, Pierre-François; Auerbach, Edwards J; Olman, Cheryl; Yacoub, Essa; Uğurbil, Kâmil; Moeller, Steen

    2009-06-01

    At high magnetic field, MR images exhibit large, undesirable signal intensity variations commonly referred to as "intensity field bias". Such inhomogeneities mostly originate from heterogeneous RF coil B(1) profiles and, with no appropriate correction, are further pronounced when utilizing rooted sum of square reconstruction with receive coil arrays. These artifacts can significantly alter whole brain high resolution T(1)-weighted (T(1)w) images that are extensively utilized for clinical diagnosis, for gray/white matter segmentation as well as for coregistration with functional time series. In T(1) weighted 3D-MPRAGE sequences, it is possible to preserve a bulk amount of T(1) contrast through space by using adiabatic inversion RF pulses that are insensitive to transmit B(1) variations above a minimum threshold. However, large intensity variations persist in the images, which are significantly more difficult to address at very high field where RF coil B(1) profiles become more heterogeneous. Another characteristic of T(1)w MPRAGE sequences is their intrinsic sensitivity to Proton Density and T(2)(*) contrast, which cannot be removed with post-processing algorithms utilized to correct for receive coil sensitivity. In this paper, we demonstrate a simple technique capable of producing normalized, high resolution T(1)w 3D-MPRAGE images that are devoid of receive coil sensitivity, Proton Density and T(2)(*) contrast. These images, which are suitable for routinely obtaining whole brain tissue segmentation at 7 T, provide higher T(1) contrast specificity than standard MPRAGE acquisitions. Our results show that removing the Proton Density component can help in identifying small brain structures and that T(2)(*) induced artifacts can be removed from the images. The resulting unbiased T(1)w images can also be used to generate Maximum Intensity Projection angiograms, without additional data acquisition, that are inherently registered with T(1)w structural images. In addition

  8. T1 weighted Brain Images at 7 Tesla Unbiased for Proton Density, T2* contrast and RF Coil Receive B1 Sensitivity with Simultaneous Vessel Visualization

    Science.gov (United States)

    Van de Moortele, Pierre-François; Auerbach, Edwards J.; Olman, Cheryl; Yacoub, Essa; Uğurbil, Kâmil; Moeller, Steen

    2009-01-01

    At high magnetic field, MR images exhibit large, undesirable signal intensity variations commonly referred to as “intensity field bias”. Such inhomogeneities mostly originate from heterogeneous RF coil B1 profiles and, with no appropriate correction, are further pronounced when utilizing rooted sum of square reconstruction with receive coil arrays. These artifacts can significantly alter whole brain high resolution T1-weighted (T1w) images that are extensively utilized for clinical diagnosis, for gray/white matter segmentation as well as for coregistration with functional time series. In T1 weighted 3D-MPRAGE sequences, it is possible to preserve a bulk amount of T1 contrast through space by using adiabatic inversion RF pulses that are insensitive to transmit B1 variations above a minimum threshold. However, large intensity variations persist in the images, which are significantly more difficult to address at very high field where RF coil B1 profiles become more heterogeneous. Another characteristic of T1w MPRAGE sequences is their intrinsic sensitivity to Proton Density and T2* contrast, which cannot be removed with post-processing algorithms utilized to correct for receive coil sensitivity. In this paper, we demonstrate a simple technique capable of producing normalized, high resolution T1w 3D-MPRAGE images that are devoid of receive coil sensitivity, Proton Density and T2* contrast. These images, which are suitable for routinely obtaining whole brain tissue segmentation at 7 Tesla, provide higher T1 contrast specificity than standard MPRAGE acquisitions. Our results show that removing the Proton Density component can help identifying small brain structures and that T2* induced artifacts can be removed from the images. The resulting unbiased T1w images can also be used to generate Maximum Intensity Projection angiograms, without additional data acquisition, that are inherently registered with T1w structural images. In addition, we introduce a simple technique

  9. Comparison of image quality in magnetic resonance imaging of the knee at 1.5 and 3.0 Tesla using 32-channel receiver coils

    International Nuclear Information System (INIS)

    Schoth, F.; Kraemer, N.; Niendorf, T.; Hohl, C.; Gunther, R.W.; Krombach, G.A.

    2008-01-01

    We examined to what degree the visualization of anatomic structures in the human knee is improved using 3.0-T magnetic resonance imaging (MRI) and many element RF receive coils as compared to 1.5 T. We imaged 20 knees at 1.5 and 3.0 T using T2-weighted STIR, T2-weighted gradient echo, T1-weighted spin-echo, true-FISP and T2-weighted fast spin echo techniques in conjunction with 32-element RF coil arrays. The 3.0-T examination was considerably faster than its 1.5-T counterpart. A superior subjective visibility at 3.0 T vs 1.5 T was found in 27 of 50 evaluated structures (meniscus, ligaments) with the exception of true-FISP techniques. The 3.0-T examination provided a better visibility (evaluated by blinded consensus-reading by two radiologists) of small structures such as the ligamentum transversum genu. Also, cartilage was better delineated at 3.0 T. A 23% increased average signal-to-noise ratio as assessed using a temporal filter was observed at 3.0 T as compared to 1.5 T. At 3.0 T, imaging of the human knee is faster and results in a subjective visibility of anatomic structures that is superior to and competitive with 1.5 T. (orig.)

  10. Correlator receiver architecture with PnpN optical thyristor operating as optical hard-limiter

    Science.gov (United States)

    Kang, Tae-Gu; Ho Lee, Su; Park, Soonchul

    2011-07-01

    We propose novel correlator receiver architecture with a PnpN optical thyristor operating as optical hard-limiter, and demonstrate a multiple-access interference rejection of the proposed correlator receiver. The proposed correlator receiver is composed of the 1×2 splitter, optical delay line, 2×1 combiner, and fabricated PnpN optical thyristor. The proposed correlator receiver enhances the system performance because it excludes some combinations of multiple-access interference patterns from causing errors as in optical code-division multiple access systems with conventional optical receiver shown in all previous works. It is found that the proposed correlator receiver can fully reject the interference signals generated by decoding processing and multiple access for two simultaneous users.

  11. Design, demonstration and analysis of a modified wavelength-correlating receiver for incoherent OCDMA system.

    Science.gov (United States)

    Zhou, Heng; Qiu, Kun; Wang, Leyang

    2011-03-28

    A novel wavelength-correlating receiver for incoherent Optical Code Division Multiple Access (OCDMA) system is proposed and demonstrated in this paper. Enabled by the wavelength conversion based scheme, the proposed receiver can support various code types including one-dimensional optical codes and time-spreading/wavelength-hopping two dimensional codes. Also, a synchronous detection scheme with time-to- wavelength based code acquisition is proposed, by which code acquisition time can be substantially reduced. Moreover, a novel data-validation methodology based on all-optical pulse-width monitoring is introduced for the wavelength-correlating receiver. Experimental demonstration of the new proposed receiver is presented and low bit error rate data-receiving is achieved without optical hard limiting and electronic power thresholding. For the first time, a detailed theoretical performance analysis specialized for the wavelength-correlating receiver is presented. Numerical results show that the overall performance of the proposed receiver prevails over conventional OCDMA receivers.

  12. Microembolic signal monitoring and the prediction of thromboembolic events following coil embolization of unruptured intracranial aneurysms: diffusion-weighted imaging correlation

    International Nuclear Information System (INIS)

    Cho, Jae-Hoon; Park, Jaechan; Kang, Dong-Hun; Kim, Yong-Won; Kim, Yong-Sun

    2015-01-01

    Microembolic signal (MES) monitoring with transcranial Doppler ultrasonography (TCD) may allow for early prediction of thromboembolisms following endovascular coiling of unruptured intracranial aneurysms (UIAs). However, the method has not gained widespread use and may benefit from correlation with diffusion-weighted imaging (DWI) of acute ischemic lesions after coiling. This purposed to evaluate the relationship between MESs and DWI-positive lesions more precisely. We conducted a prospective study on 45 consecutive patients. TCD was performed over the artery that is dependent on the site of aneurysm, but seven patients (15.6 %) could not be examined due to the lack of an adequate cranial window. Consequently, 38 patients were available to detect MESs immediately (MES-1) and 24 h (MES-2) after coiling for UIAs. We also checked DWI 1 day after the coiling and analyzed correlations between the TCD and DWI findings. MES-1 and MES-2 were positive in 25 (65.7 %) and 14 (36.8 %) patients, respectively. DWI-positive lesions were seen in 20 (52.6 %) patients, and only 1 (2.6 %) patient was symptomatic. MES-1 and MES-2 were strongly correlated with the number of DWI-positive lesions (Spearman's correlation coefficient = 0.79 and 0.70, P < 0.01 and P < 0.01, respectively). Additionally, there was a significant correlation between MES-1 and MES-2 (Spearman's correlation coefficient = 0.70). Based upon the significant correlation between MES and DWI findings, MES may have a role for early detection of ischemic complications after coiling of UIAs. In addition, future study for further validation with clinical application seems requiring. (orig.)

  13. Full-scale locomotive dynamic crash testing and correlations : locomotive consist colliding with steel coil truck at grade crossing (test 3).

    Science.gov (United States)

    2011-09-01

    This report presents the test results and finite element correlations of a full-scale dynamic collision between a locomotive and a highway truck loaded with two heavy steel coils. The locomotive consist was moving at 58 miles per hour before it struc...

  14. Asymmetric Joint Source-Channel Coding for Correlated Sources with Blind HMM Estimation at the Receiver

    Directory of Open Access Journals (Sweden)

    Ser Javier Del

    2005-01-01

    Full Text Available We consider the case of two correlated sources, and . The correlation between them has memory, and it is modelled by a hidden Markov chain. The paper studies the problem of reliable communication of the information sent by the source over an additive white Gaussian noise (AWGN channel when the output of the other source is available as side information at the receiver. We assume that the receiver has no a priori knowledge of the correlation statistics between the sources. In particular, we propose the use of a turbo code for joint source-channel coding of the source . The joint decoder uses an iterative scheme where the unknown parameters of the correlation model are estimated jointly within the decoding process. It is shown that reliable communication is possible at signal-to-noise ratios close to the theoretical limits set by the combination of Shannon and Slepian-Wolf theorems.

  15. Sequence correction of random coil chemical shifts: correlation between neighbor correction factors and changes in the Ramachandran distribution

    DEFF Research Database (Denmark)

    Kjærgaard, Magnus; Poulsen, Flemming Martin

    2011-01-01

    Random coil chemical shifts are necessary for secondary chemical shift analysis, which is the main NMR method for identification of secondary structure in proteins. One of the largest challenges in the determination of random coil chemical shifts is accounting for the effect of neighboring residues....... The contributions from the neighboring residues are typically removed by using neighbor correction factors determined based on each residue's effect on glycine chemical shifts. Due to its unusual conformational freedom, glycine may be particularly unrepresentative for the remaining residue types. In this study, we...... in the conformational ensemble are an important source of neighbor effects in disordered proteins. Glutamine derived random coil chemical shifts and correction factors modestly improve our ability to predict (13)C chemical shifts of intrinsically disordered proteins compared to existing datasets, and may thus improve...

  16. Borehole induction coil transmitter

    Science.gov (United States)

    Holladay, Gale; Wilt, Michael J.

    2002-01-01

    A borehole induction coil transmitter which is a part of a cross-borehole electromagnetic field system that is used for underground imaging applications. The transmitter consists of four major parts: 1) a wound ferrite or mu-metal core, 2) an array of tuning capacitors, 3) a current driver circuit board, and 4) a flux monitor. The core is wound with several hundred turns of wire and connected in series with the capacitor array, to produce a tuned coil. This tuned coil uses internal circuitry to generate sinusoidal signals that are transmitted through the earth to a receiver coil in another borehole. The transmitter can operate at frequencies from 1-200 kHz and supplies sufficient power to permit the field system to operate in boreholes separated by up to 400 meters.

  17. Low Computational Signal Acquisition for GNSS Receivers Using a Resampling Strategy and Variable Circular Correlation Time

    Directory of Open Access Journals (Sweden)

    Yeqing Zhang

    2018-02-01

    Full Text Available For the objective of essentially decreasing computational complexity and time consumption of signal acquisition, this paper explores a resampling strategy and variable circular correlation time strategy specific to broadband multi-frequency GNSS receivers. In broadband GNSS receivers, the resampling strategy is established to work on conventional acquisition algorithms by resampling the main lobe of received broadband signals with a much lower frequency. Variable circular correlation time is designed to adapt to different signal strength conditions and thereby increase the operation flexibility of GNSS signal acquisition. The acquisition threshold is defined as the ratio of the highest and second highest correlation results in the search space of carrier frequency and code phase. Moreover, computational complexity of signal acquisition is formulated by amounts of multiplication and summation operations in the acquisition process. Comparative experiments and performance analysis are conducted on four sets of real GPS L2C signals with different sampling frequencies. The results indicate that the resampling strategy can effectively decrease computation and time cost by nearly 90–94% with just slight loss of acquisition sensitivity. With circular correlation time varying from 10 ms to 20 ms, the time cost of signal acquisition has increased by about 2.7–5.6% per millisecond, with most satellites acquired successfully.

  18. Low Computational Signal Acquisition for GNSS Receivers Using a Resampling Strategy and Variable Circular Correlation Time

    Science.gov (United States)

    Zhang, Yeqing; Wang, Meiling; Li, Yafeng

    2018-01-01

    For the objective of essentially decreasing computational complexity and time consumption of signal acquisition, this paper explores a resampling strategy and variable circular correlation time strategy specific to broadband multi-frequency GNSS receivers. In broadband GNSS receivers, the resampling strategy is established to work on conventional acquisition algorithms by resampling the main lobe of received broadband signals with a much lower frequency. Variable circular correlation time is designed to adapt to different signal strength conditions and thereby increase the operation flexibility of GNSS signal acquisition. The acquisition threshold is defined as the ratio of the highest and second highest correlation results in the search space of carrier frequency and code phase. Moreover, computational complexity of signal acquisition is formulated by amounts of multiplication and summation operations in the acquisition process. Comparative experiments and performance analysis are conducted on four sets of real GPS L2C signals with different sampling frequencies. The results indicate that the resampling strategy can effectively decrease computation and time cost by nearly 90–94% with just slight loss of acquisition sensitivity. With circular correlation time varying from 10 ms to 20 ms, the time cost of signal acquisition has increased by about 2.7–5.6% per millisecond, with most satellites acquired successfully. PMID:29495301

  19. SSC Diversity Receiver over Correlated Fading Channels in the Presence of Cochannel Interference

    Directory of Open Access Journals (Sweden)

    Panić StefanR

    2010-01-01

    Full Text Available This paper studies the performances of a dual-branch switched-and-stay combining (SSC diversity receiver, operating over correlated fading in the presence of cochannel interference (CCI. Very useful, novel, infinite series expressions are obtained for the output signal to interference ratio's (SIR's probability density function (PDF and cumulative distribution function (CDF. The performance analysis is based on an outage probability (OP and an average bit error probability (ASEP criteria. ASEP is efficiently evaluated for modulation schemes such as noncoherent frequency-shift keying (NCFSK and binary differentially phase-shift keying (BDPSK. The effects of various parameters, such as input SIR unbalance, the level of correlation between received desired signals and interferences, nonlinearity of the environment, and fading severity on systems performances are graphically presented and analyzed.

  20. Correlation of volatile carbonyl yields emitted by e-cigarettes with the temperature of the heating coil and the perceived sensorial quality of the generated vapours.

    Science.gov (United States)

    Geiss, Otmar; Bianchi, Ivana; Barrero-Moreno, Josefa

    2016-05-01

    E-liquids generally contain four main components: nicotine, flavours, water and carrier liquids. The carrier liquid dissolves flavours and nicotine and vaporises at a certain temperature on the atomizer of the e-cigarette. Propylene glycol and glycerol, the principal carriers used in e-liquids, undergo decomposition in contact with the atomizer heating-coil forming volatile carbonyls. Some of these, such as formaldehyde, acetaldehyde and acrolein, are of concern due to their adverse impact on human health when inhaled at sufficient concentrations. The aim of this study was to correlate the yield of volatile carbonyls emitted by e-cigarettes with the temperature of the heating coil. For this purpose, a popular commercial e-liquid was machine-vaped on a third generation e-cigarette which allowed the variation of the output wattage (5-25W) and therefore the heat generated on the atomizer heating-coil. The temperature of the heating-coil was determined by infrared thermography and the vapour generated at each temperature underwent subjective sensorial quality evaluation by an experienced vaper. A steep increase in the generated carbonyls was observed when applying a battery-output of at least 15W corresponding to 200-250°C on the heating coil. However, when considering concentrations in each inhaled puff, the short-term indoor air guideline value for formaldehyde was already exceeded at the lowest wattage of 5W, which is the wattage applied in most 2nd generation e-cigarettes. Concentrations of acetaldehyde in each puff were several times below the short-term irritation threshold value for humans. Acrolein was only detected from 20W upwards. The negative sensorial quality evaluation by the volunteering vaper of the vapour generated at 20W demonstrated the unlikelihood that such a wattage would be realistically set by a vaper. This study highlights the importance to develop standardised testing methods for the assessment of carbonyl-emissions and emissions of other

  1. Predictors and Correlates of Follow-up Visit Adherence among Adolescents Receiving Laparoscopic Adjustable Gastric Banding

    Science.gov (United States)

    Sysko, Robyn; Hildebrandt, Tom B.; Kaplan, Simona; Brewer, Stephanie K.; Zitsman, Jeffrey L.; Devlin, Michael J.

    2014-01-01

    Background Adherence behaviors have not been examined among adolescents undergoing laparoscopic adjustable gastric banding (LAGB). In addition, studies of youth receiving bariatric surgery have not considered the influence of psychopathology on postoperative adherence. Objective The purpose of this study was to evaluate predictors and correlates of adherence to post-surgery visits among a sample of adolescents undergoing LAGB. Setting Psychiatry Department, University Medical Center, United States. Methods Postoperative visits with surgical staff were analyzed over the two years following surgery (n= 101 adolescents). Growth mixture modeling examined trends in adherence. Results A three-class solution provided the best fit to the data. The classes from the final model were characterized by class 1 (61.6%) demonstrating high levels of adherence over the 24 months following LAGB, class 2 (28.5%) showing a more gradual decline in adherence, and class 3 (9.9%) with an accelerated decline in adherence. Higher levels of preoperative depressive symptoms and more preoperative episodes of loss of control over eating decreased the likelihood of adherence. Class 3 adolescents had significantly higher estimated 24-month body mass indices than Classes 1 or 2. Conclusions Variable patterns of follow-up visit adherence were identified among adolescents receiving LAGB, which were predicted by depressive symptoms and loss of control over eating. The trajectory characterized by a rapid decline in adherence to follow-up visits was also associated with less weight loss. PMID:25066443

  2. The incidence of anxiety and its correlates in cancer patients receiving radiotherapy

    International Nuclear Information System (INIS)

    Iqbal, A.; Siddiqui, K.S.

    2002-01-01

    Objective: To observe the incidence of anxiety in radiotherapy cancer patients in relation to their age, gender, education, marital status, performance status and type of disease. Design: Data regarding socio-demographic variables and disease type was recorded on a data capture form. The presence of anxiety was measured by administering taylor Manifest Anxiety Scale, Whereas patients, performance status was measured by administering Kernosky Performance Status Scale. Setting: Patients coming to the Department of Radiation Oncology, Shaukat Khanum Memorial Cancer Hospital and research center for their treatment were included in this study. Subjects and methods: A consecutive sample of 113 patients was taken and followed up to study the incidence of anxiety. Data over various parameters like age, gender, education, marital status, disease type and performance status was recorded. Results: Fifty percent of cancer patients receiving radiotherapy were found to be suffering from anxiety. Among 89% of patients, anxiety lowered after the therapy, in 3% it increased and remained static in 8% Patients with low education and low performance status presented with high anxiety. Among all the patients, no significant relationship between anxiety and gender, age, marital status and site of the disease was observed. Conclusion: Correlates other than radiotherapy procedure can also cause anxiety in patients by further research is required to establish those correlates of anxiety. It is recommended that all radiotherapy patients should be provided education and procedural information designed to familiarize them with the forthcoming experience in order to reduce their anxiety. (author)

  3. Prevalence and correlates of cigarette smoking among Chinese schizophrenia inpatients receiving antipsychotic mono-therapy.

    Directory of Open Access Journals (Sweden)

    Yan-Min Xu

    Full Text Available OBJECTIVE: To investigate the prevalence rate of cigarette smoking and its socio-demographic and clinical correlates in Chinese schizophrenia inpatients receiving antipsychotic mono-therapy. METHODS: This study was a cross-sectional, two-site, hospital-based survey. Four hundred and twenty-nine schizophrenia patients (male/female: 66.9% vs. 33.1% were consecutively recruited from psychosis inpatient wards of two large specialty psychiatric hospitals in mainland China. Patients were assessed using a cigarette smoking questionnaire, the Positive and Negative Symptom Scale, the Simpson Angus Scale, the Barnes Akathisia Rating Scale, and the Abnormal Involuntary Movement Scale. Socio-demographic and other clinical data were also collected. We calculated the prevalence of current smoking in our sample as well as its indirectly standardized prevalence ratio (ISPR using data from the 2010 Global Adult Tobacco Survey in China. RESULTS: The prevalence rate of current smoking was 40.6% in our sample, and 57.5% in males and 6.3% in females. The ISPRs of all patients, men and women were 1.11(95%CI: 0.95 ∼ 1.29, 1.07(95%CI = 0.91 ∼ 1.24 and 4.64(95% CI = 2.12 ∼ 8.82, respectively. The overall and male-specific prevalence of current smoking did not differ significantly between patients and the general population. In multiple logistic regression analysis, male sex, older age, poor marital status, alcohol use, use of first-generation antipsychotics, longer duration of illness, more frequent hospitalizations, and more severe negative symptoms were independently associated with current smoking. CONCLUSION: Male Chinese inpatients with schizophrenia who received a mono-therapy of antipsychotics were not more likely to smoke than the general population. Cigarette smoking is more common in schizophrenia patients with more severe illness.

  4. Superconducting cyclotron magnet coil short

    International Nuclear Information System (INIS)

    Mallory, M.L.; Blosser, H.G.; Clark, D.J.; Launer, H.; Lawton, D.; Miller, P.; Resmini, F.

    1982-01-01

    In February 1981, a short circuit appeared in the superconducting coil of the K500 cyclotron. The short is resistive in character and therefore has no effect on steady state operation of the magnet. The resistance of the short varies, sometimes being below threshold of detection as a heat load on the cooling system and sometimes being significant. The resistance under certain conditions shows approximately cyclic phenomena with time constants in the range of seconds and other approximately cyclic phenomena which correlate with gross operating parameters of the magnet (shifting current from one coil to another at high field and lowering and raising the liquid helium level). A number of diagnostic studies of the short have been made, using 1) an array of flux sensing loops to sense the magnetic effect of the short, 2) voltage comparisons between upper and lower sections of the coil, 3) comparisons of forces in the nine member coil support system and 4) the effect of the short on the thermal charactersitics of the coil. Insulation failure or a metal chip shorting out turns have been explored in some detail but a convincing determination of the exact cause of the short may never be available, (even the extreme step of unwinding the coil having a significant probability that an imperfection with the observed characteristics would pass unnoticed). Analysis of the characteristics of the short indicated that the most serious consequence would be failure of the coils mechanical support system in the event that the magnet was quickly discharged, as in a dump or quench. To deal with this hazard, the support system has been modified by installing solid supports which prevent the coil from moving by an amount sufficient to damage the support system. We have also reexamined the data and calculations used in the original coil design and have made some additional measurements of the properties of the materials (yield strength, friction coefficient, Young's modulus) used in the

  5. Representatives of the companies receiving CMS Gold Awards on 15 March, pictured in front of the first superconducting coil module at the experiment construction site.

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    The fifth annual CMS awards ceremony was held at CERN on 15 March. This year, six of the approximately 1000 companies who work for CMS were honoured with the Gold Award for demonstrating excellence by providing parts on schedule, within budget and within specification. Two of the prize-winners also received the Crystal Award, which is given to a company that has taken further efforts to develop new designs, explore novel technologies and collaborate in research and development program

  6. Three-axis orthogonal transceiver coil for eddy current sounding

    Science.gov (United States)

    Sukhanov, D.; Zavyalova, K.; Goncharik, M.

    2017-08-01

    We propose the new structure of three-axis transceiver magnetic-induction coil for eddy current probing. Due to the orientation of the coils, the direct signal from the transmitting coil to the receiving coil is minimized, which provided a high dynamic range. Sensitivity in all directions is provided by combining coils of different orientations. Numerical simulation and experimental studies of such a system have been carried out and confirmed the applicability of the proposed method and the mathematical model.

  7. Diffusion tensor imaging using multiple coils for mouse brain connectomics.

    Science.gov (United States)

    Nouls, John C; Badea, Alexandra; Anderson, Robert B J; Cofer, Gary P; Allan Johnson, G

    2018-04-19

    The correlation between brain connectivity and psychiatric or neurological diseases has intensified efforts to develop brain connectivity mapping techniques on mouse models of human disease. The neural architecture of mouse brain specimens can be shown non-destructively and three-dimensionally by diffusion tensor imaging, which enables tractography, the establishment of a connectivity matrix and connectomics. However, experiments on cohorts of animals can be prohibitively long. To improve throughput in a 7-T preclinical scanner, we present a novel two-coil system in which each coil is shielded, placed off-isocenter along the axis of the magnet and connected to a receiver circuit of the scanner. Preservation of the quality factor of each coil is essential to signal-to-noise ratio (SNR) performance and throughput, because mouse brain specimen imaging at 7 T takes place in the coil-dominated noise regime. In that regime, we show a shielding configuration causing no SNR degradation in the two-coil system. To acquire data from several coils simultaneously, the coils are placed in the magnet bore, around the isocenter, in which gradient field distortions can bias diffusion tensor imaging metrics, affect tractography and contaminate measurements of the connectivity matrix. We quantified the experimental alterations in fractional anisotropy and eigenvector direction occurring in each coil. We showed that, when the coils were placed 12 mm away from the isocenter, measurements of the brain connectivity matrix appeared to be minimally altered by gradient field distortions. Simultaneous measurements on two mouse brain specimens demonstrated a full doubling of the diffusion tensor imaging throughput in practice. Each coil produced images devoid of shading or artifact. To further improve the throughput of mouse brain connectomics, we suggested a future expansion of the system to four coils. To better understand acceptable trade-offs between imaging throughput and connectivity

  8. A new type of coil structure called pan-shaped coil of wireless charging system based on magnetic resonance

    Science.gov (United States)

    Yue, Z. K.; Liu, Z. Z.; Hou, Y. J.; Zeng, H.; Liang, L. H.; Cui, S.

    2017-11-01

    The problem that misalignment between the transmitting coil and the receiving coil significantly impairs the transmission power and efficiency of the system has been attached more and more attention. In order to improve the uniformity of the magnetic field between the two coils to solve this problem, a new type of coil called pan-shaped coil is proposed. Three-dimension simulation models of the planar-core coil and the pan-shaped coil are established using Ansoft Maxwell software. The coupling coefficient between the transmitting coil and the receiving coil is obtained by simulating the magnetic field with the receiving coil misalignment or not. And the maximum percentage difference strength along the radial direction which is defined as the magnetic field uniformity factor is calculated. According to the simulation results of the two kinds of coil structures, it is found that the new type of coil structure can obviously improve the uniformity of the magnetic field, coupling coefficient and power transmission properties between the transmitting coil and the receiving coil.

  9. Multicoil2: predicting coiled coils and their oligomerization states from sequence in the twilight zone.

    Directory of Open Access Journals (Sweden)

    Jason Trigg

    Full Text Available The alpha-helical coiled coil can adopt a variety of topologies, among the most common of which are parallel and antiparallel dimers and trimers. We present Multicoil2, an algorithm that predicts both the location and oligomerization state (two versus three helices of coiled coils in protein sequences. Multicoil2 combines the pairwise correlations of the previous Multicoil method with the flexibility of Hidden Markov Models (HMMs in a Markov Random Field (MRF. The resulting algorithm integrates sequence features, including pairwise interactions, through multinomial logistic regression to devise an optimized scoring function for distinguishing dimer, trimer and non-coiled-coil oligomerization states; this scoring function is used to produce Markov Random Field potentials that incorporate pairwise correlations localized in sequence. Multicoil2 significantly improves both coiled-coil detection and dimer versus trimer state prediction over the original Multicoil algorithm retrained on a newly-constructed database of coiled-coil sequences. The new database, comprised of 2,105 sequences containing 124,088 residues, includes reliable structural annotations based on experimental data in the literature. Notably, the enhanced performance of Multicoil2 is evident when tested in stringent leave-family-out cross-validation on the new database, reflecting expected performance on challenging new prediction targets that have minimal sequence similarity to known coiled-coil families. The Multicoil2 program and training database are available for download from http://multicoil2.csail.mit.edu.

  10. Generalized Frequency-Domain Correlator for Software GPS Receiver: Preliminary Test Results and Analysis (PREPRINT)

    National Research Council Canada - National Science Library

    Yang, Chun; Miller, Mikel; Nguyen, Thao; Akos, Dennis

    2006-01-01

    .... The use of a GFDC can offer several advantages. First, as a generalization of the FFT-implemented correlation with a block repetitive processing capability, it enables fast acquisition through simultaneous code delay and Doppler frequency search...

  11. Using GRAPPA to improve autocalibrated coil sensitivity estimation for the SENSE family of parallel imaging reconstruction algorithms.

    Science.gov (United States)

    Hoge, W Scott; Brooks, Dana H

    2008-08-01

    Two strategies are widely used in parallel MRI to reconstruct subsampled multicoil image data. SENSE and related methods employ explicit receiver coil spatial response estimates to reconstruct an image. In contrast, coil-by-coil methods such as GRAPPA leverage correlations among the acquired multicoil data to reconstruct missing k-space lines. In self-referenced scenarios, both methods employ Nyquist-rate low-frequency k-space data to identify the reconstruction parameters. Because GRAPPA does not require explicit coil sensitivities estimates, it needs considerably fewer autocalibration signals than SENSE. However, SENSE methods allow greater opportunity to control reconstruction quality though regularization and thus may outperform GRAPPA in some imaging scenarios. Here, we employ GRAPPA to improve self-referenced coil sensitivity estimation in SENSE and related methods using very few auto-calibration signals. This enables one to leverage each methods' inherent strength and produce high quality self-referenced SENSE reconstructions. (c) 2008 Wiley-Liss, Inc.

  12. Correlation of endorectal coil magnetic resonance, transrectal ultrasound and radical prostatectomy findings in assessing extent of prostate cancer in referred urology patients

    International Nuclear Information System (INIS)

    Lavoipierre, A.; Little, A.F.; Greive, K.A.; Royce, P.L.; Snow, R.M.; Frydenberg, M.

    2002-01-01

    Full text: The aim of this study was to compare findings at prostate MR to ultrasound findings and pathology specimens in patients who subsequently underwent radical prostatectomy. Of the 61 patients who underwent composite MR prostate imaging, 39 patients with elevated PSA levels and / or abnormal DRE findings were found to have cancer on transrectal ultrasound (TRUS) and biopsy (random sextant and targeted biopsies). MRI was performed using composite phased array and endorectal coils, using axial T1 and axial, coronal and sagittal T2 weighted images through the prostate, together with axial T1 weighted imaging through the pelvis. Fifteen patients out the 39 patients with documented cancer then underwent radical prostatectomy. The resected specimen pathology was then compared with the MR and TRUS findings. Comparison of findings at MRI with those at prostatectomy indicated approximately 82.4% correlation comparing right side and left side disease (TRUS = 80%). There was a 13.3% false positive for seminal vesicle involvement on MR (TRUS = 0%) and a 10% false negative rate on MR (TRUS 10%) compared with pathology specimens.There was a 26.7% false positive rate of extracapsular extension on MR (TRUS = 0%) and a 6.6% false negative rate on MR (TRUS = 20%) compared with the pathology specimens. Of the 39 patients who had undergone TRUS and biopsy, the disease appeared more extensive on MRI than suspected at ultrasound in 14/39 (35.9%). High resolution MR imaging of the prostate is an acceptable method for assessing the presence of prostate cancer. However, our early experience, in this small series, suggests that there is a high mis-staging of disease on MR as is the case with TRUS, although MR is better than TRUS. The results underscore the need for additional assessment with MR spectroscopy. Copyright (2002) Blackwell Science Pty Ltd

  13. Neural correlates of receiving an apology and active forgiveness: an FMRI study.

    Science.gov (United States)

    Strang, Sabrina; Utikal, Verena; Fischbacher, Urs; Weber, Bernd; Falk, Armin

    2014-01-01

    Interpersonal conflicts are a common element of many social relationships. One possible process in rebuilding social relationships is the act of apologizing. Behavioral studies have shown that apologies promote forgiveness. However, the neural bases of receiving an apology and forgiveness are still unknown. Hence, the aim of the present fMRI study was to investigate brain processes involved in receiving an apology and active forgiveness of an ambiguous offense. We asked one group of participants (player A) to make decisions, which were either positive or negative for another group of participants (player B). The intention of player A was ambiguous to player B. In case of a negative impact, participants in the role of player A could send an apology message to participants in the role of player B. Subsequently players B were asked whether they wanted to forgive player A for making a decision with negative consequences. We found that receiving an apology yielded activation in the left inferior frontal gyrus, the left middle temporal gyrus, and left angular gyrus. In line with previous research we found that forgiving judgments activated the right angular gyrus.

  14. Conception of Brownian coil

    OpenAIRE

    Zhang, Jiayuan

    2018-01-01

    This article proposes a conception of Brownian coil. Brownian coil is a tiny coil with the same size of pollen. Once immersed into designed magnetic field and liquid, the coil will be moved and deformed macroscopically, due to the microscopic thermodynamic molecular collisions. Such deformation and movement will change the magnetic flux through the coil, by which an ElectroMotive Force (EMF) is produced. In this work, Brownian heat exchanger and Brownian generator are further designed to tran...

  15. Correlation of Serum Cystatin C with Glomerular Filtration Rate in Patients Receiving Platinum-Based Chemotherapy

    Directory of Open Access Journals (Sweden)

    Ernesta Cavalcanti

    2016-01-01

    Full Text Available Objectives. Serum cystatin C seems to be an accurate marker of glomerular filtration rate (GFR compared to serum creatinine. The aim of this work was to explore the possibility of using serum cystatin C instead of serum creatinine to early predict renal failure in cancer patients who received platinum based chemotherapy. Design and Methods. Serum creatinine, serum cystatin C concentrations, and GFR were determined simultaneously in 52 cancer patients received carboplatin-based or cisplatin-based chemotherapy. Serum creatinine was assayed on Cobas C6000-Roche, serum cystatin C assay was performed on AIA 360-Tosoh, and GFR was determined in all patients, before the first cycle of chemotherapy and before the subsequent administrations. Results. In the overall series, for the prediction of a fall of GFR < 80 mL/min/1.73 m2, the AUC of the ROC curve for cystatin C was 0,667 and the best threshold was 1.135 mg/L (sensitivity 90.5%, specificity 61.1%. For a GFR fall < 60 mL/min/1.73 m2, the AUC of ROC curve for cystatin C was 74.3% and the best threshold was 1.415 mg/L (sensitivity 66.7%, specificity 73.2%. Conclusions. Baseline cystatin C values were not able to predict renal failure during subsequent treatment. In conclusion, serum cystatin C is not a reliable early marker to efficiently predict renal failure in patients receiving chemotherapy.

  16. Analysis and experimental study of wireless power transfer with HTS coil and copper coil as the intermediate resonators system

    International Nuclear Information System (INIS)

    Wang, Xiufang; Nie, Xinyi; Liang, Yilang; Lu, Falong; Yan, Zhongming; Wang, Yu

    2017-01-01

    Highlights: • We investigated a kind of system architecture with three coils which the repeater is copper coil or HTS coil. • We simulated the different repeater system and obtained the magnetic field distribution at different distance. • We used helical coil instead of pancake coil which does not use capacitors. • HTS intermediate coil has significant effect on improving the transmission efficiency and lengthening transmission distance than copper intermediate coil. - Abstract: Intermediate resonator (repeater) between transmitter and receiver can significantly increase the distance of wireless power transfer (WPT) and the efficiency of wireless power transfer. The wireless power transfer via strongly coupled magnetic resonances with an high temperature superconducting (HTS) coil and copper coil as intermediate resonators was presented in this paper. The electromagnetic experiment system under different conditions with different repeating coils were simulated by finite element software. The spatial distribution patterns of magnetic induction intensity at different distances were plotted. In this paper, we examined transfer characteristics with HTS repeating coil and copper repeating coil at 77 K and 300 K, respectively. Simulation and experimental results show that HTS and copper repeating coil can effectively enhance the space magnetic induction intensity, which has significant effect on improving the transmission efficiency and lengthening transmission distance. We found that the efficiency and the distance of wireless power transfer system with an HTS coil as repeater is much higher by using of copper coil as repeater.

  17. Analysis and experimental study of wireless power transfer with HTS coil and copper coil as the intermediate resonators system

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Xiufang [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); School of Physics and Technology, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Nie, Xinyi [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Liang, Yilang [School of Physics and Technology, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Lu, Falong [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Yan, Zhongming, E-mail: wangxiufanghappy@163.com [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Wang, Yu [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China)

    2017-01-15

    Highlights: • We investigated a kind of system architecture with three coils which the repeater is copper coil or HTS coil. • We simulated the different repeater system and obtained the magnetic field distribution at different distance. • We used helical coil instead of pancake coil which does not use capacitors. • HTS intermediate coil has significant effect on improving the transmission efficiency and lengthening transmission distance than copper intermediate coil. - Abstract: Intermediate resonator (repeater) between transmitter and receiver can significantly increase the distance of wireless power transfer (WPT) and the efficiency of wireless power transfer. The wireless power transfer via strongly coupled magnetic resonances with an high temperature superconducting (HTS) coil and copper coil as intermediate resonators was presented in this paper. The electromagnetic experiment system under different conditions with different repeating coils were simulated by finite element software. The spatial distribution patterns of magnetic induction intensity at different distances were plotted. In this paper, we examined transfer characteristics with HTS repeating coil and copper repeating coil at 77 K and 300 K, respectively. Simulation and experimental results show that HTS and copper repeating coil can effectively enhance the space magnetic induction intensity, which has significant effect on improving the transmission efficiency and lengthening transmission distance. We found that the efficiency and the distance of wireless power transfer system with an HTS coil as repeater is much higher by using of copper coil as repeater.

  18. Prevalence and correlates of sleep-related problems in adults receiving medical cannabis for chronic pain.

    Science.gov (United States)

    Cranford, James A; Arnedt, J Todd; Conroy, Deirdre A; Bohnert, Kipling M; Bourque, Carrie; Blow, Frederic C; Ilgen, Mark

    2017-11-01

    To examine the prevalence and correlates of sleep problems in a sample of medical cannabis patients. Adults ages 21 and older (N=801,M age=45.8) who were seeking medical cannabis certification (either for the first time or as a renewal) for chronic pain at medical cannabis clinics in southern Michigan completed baseline measures of cannabis use, sleep, pain, and other related constructs. Over half of the sample (59%) met criteria for past 1-month sleep disturbance, defined as at least one sleep problem occurring on 15 or more nights in the past month. Most participants (86%) reported that sleep problems were due to their current pain. Approximately 80% of participants reported using cannabis in the past 6 months to improve sleep and, among these participants, cannabis was rated as helpful for improving sleep. Sleep-related cannabis side effects were rare (35%), but sleep-related cannabis withdrawal symptoms were relatively common (65%). Statistically significant correlates of past 1-month sleep disturbance included a) being female, b) being white, c) being on disability, d) not having a medical cannabis card, and e) frequency of using cannabis to help sleep. Sleep problems are highly prevalent and frequent in medical cannabis patients and are closely tied to pain. Sleep-related cannabis withdrawal symptoms are relatively common but their clinical relevance is unknown. The association between frequency of cannabis use to help sleep with higher odds of sleep problems will need to be clarified by longitudinal studies. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Channel correlation of free space optical communication systems with receiver diversity in non-Kolmogorov atmospheric turbulence

    Science.gov (United States)

    Ma, Jing; Fu, Yulong; Tan, Liying; Yu, Siyuan; Xie, Xiaolong

    2018-05-01

    Spatial diversity as an effective technique to mitigate the turbulence fading has been widely utilized in free space optical (FSO) communication systems. The received signals, however, will suffer from channel correlation due to insufficient spacing between component antennas. In this paper, the new expressions of the channel correlation coefficient and specifically its components (the large- and small-scale channel correlation coefficients) for a plane wave with aperture effects are derived for horizontal link in moderate-to-strong turbulence, using a non-Kolmogorov spectrum that has a generalized power law in the range of 3-4 instead of the fixed classical Kolmogorov power law of 11/3. And then the influence of power law variations on the channel correlation coefficient and its components are analysed. The numerical results indicated that various value of the power law lead to varying effects on the channel correlation coefficient and its components. This work will help with the further investigation on the fading correlation in spatial diversity systems.

  20. Water cooling coil

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, S; Ito, Y; Kazawa, Y

    1975-02-05

    Object: To provide a water cooling coil in a toroidal nuclear fusion device, in which coil is formed into a small-size in section so as not to increase dimensions, weight or the like of machineries including the coil. Structure: A conductor arranged as an outermost layer of a multiple-wind water cooling coil comprises a hollow conductor, which is directly cooled by fluid, and as a consequence, a solid conductor disposed interiorly thereof is cooled indirectly.

  1. NCSX Trim Coil Design

    International Nuclear Information System (INIS)

    Kalish, M.; Brooks, A.; Rushinski, J.; Upcavage, R.

    2009-01-01

    The National Compact Stellarator Experiment (NCSX) was being constructed at the Princeton Plasma Physics Laboratory in partnership with Oak Ridge National Laboratory before work was stopped in 2008. The objective of this experiment was to develop the stellarator concept and evaluate it's potential as a model for future fusion power plants. Stellarator design requires very precisely positioned Modular Coils of complex shape to form 3D plasmas. In the design of NCSX, Trim Coils were required to compensate for both the positioning of the coils during assembly and the fabrication tolerances of the Modular Coils. Use of the Trim Coils allowed for larger tolerances increasing ease of assembly and decreasing overall cost. A set of Trim coils was developed to suppress the toroidal flux in island regions due to misalignment, magnetic materials, and eddy currents. The requirement imposed upon the design forced the toroidal flux in island regions below 10% of the total toroidal flux in the plasma. An analysis was first performed to evaluate candidate Trim Coil configurations iterating both the size, number, and position of the coils. The design was optimized considering both performance and cost while staying within the tight restraints presented by the space limited geometry. The final design of the Trim Coils incorporated a 48 Coil top bottom symmetric set. Fabrication costs were minimized by having only two coil types and using a planar conventional design with off the shelf commercial conductor. The Trim Coil design incorporated supports made from simple structural shapes assembled together in a way which allowed for adjustment as well as accommodation for the tolerance build up on the mating surfaces. This paper will summarize the analysis that led to the optimization of the Trim Coils set, the trim coil mechanical design, thermal and stress analysis, and the design of the supporting Trim Coil structure

  2. Dual coil ignition system

    Energy Technology Data Exchange (ETDEWEB)

    Huberts, Garlan J.; Qu, Qiuping; Czekala, Michael Damian

    2017-03-28

    A dual coil ignition system is provided. The dual coil ignition system includes a first inductive ignition coil including a first primary winding and a first secondary winding, and a second inductive ignition coil including a second primary winding and a second secondary winding, the second secondary winding connected in series to the first secondary winding. The dual coil ignition system further includes a diode network including a first diode and a second diode connected between the first secondary winding and the second secondary winding.

  3. Biomaterials Made from Coiled-Coil Peptides.

    Science.gov (United States)

    Conticello, Vincent; Hughes, Spencer; Modlin, Charles

    The development of biomaterials designed for specific applications is an important objective in personalized medicine. While the breadth and prominence of biomaterials have increased exponentially over the past decades, critical challenges remain to be addressed, particularly in the development of biomaterials that exhibit highly specific functions. These functional properties are often encoded within the molecular structure of the component molecules. Proteins, as a consequence of their structural specificity, represent useful substrates for the construction of functional biomaterials through rational design. This chapter provides an in-depth survey of biomaterials constructed from coiled-coils, one of the best-understood protein structural motifs. We discuss the utility of this structurally diverse and functionally tunable class of proteins for the creation of novel biomaterials. This discussion illustrates the progress that has been made in the development of coiled-coil biomaterials by showcasing studies that bridge the gap between the academic science and potential technological impact.

  4. Superconducting magnetic coil

    Science.gov (United States)

    Aized, Dawood; Schwall, Robert E.

    1996-06-11

    A superconducting magnetic coil includes a plurality of sections positioned axially along the longitudinal axis of the coil, each section being formed of an anisotropic high temperature superconductor material wound about a longitudinal axis of the coil and having an associated critical current value that is dependent on the orientation of the magnetic field of the coil. The cross section of the superconductor, or the type of superconductor material, at sections along the axial and radial axes of the coil are changed to provide an increased critical current at those regions where the magnetic field is oriented more perpendicularly to the conductor plane, to thereby increase the critical current at these regions and to maintain an overall higher critical current of the coil.

  5. A Specialized Multi-Transmit Head Coil for High Resolution fMRI of the Human Visual Cortex at 7T.

    Science.gov (United States)

    Sengupta, Shubharthi; Roebroeck, Alard; Kemper, Valentin G; Poser, Benedikt A; Zimmermann, Jan; Goebel, Rainer; Adriany, Gregor

    2016-01-01

    To design, construct and validate radiofrequency (RF) transmit and receive phased array coils for high-resolution visual cortex imaging at 7 Tesla. A 4 channel transmit and 16 channel receive array was constructed on a conformal polycarbonate former. Transmit field efficiency and homogeneity were simulated and validated, along with the Specific Absorption Rate, using [Formula: see text] mapping techniques and electromagnetic simulations. Receiver signal-to-noise ratio (SNR), temporal SNR (tSNR) across EPI time series, g-factors for accelerated imaging and noise correlations were evaluated and compared with a commercial 32 channel whole head coil. The performance of the coil was further evaluated with human subjects through functional MRI (fMRI) studies at standard and submillimeter resolutions of upto 0.8mm isotropic. The transmit and receive sections were characterized using bench tests and showed good interelement decoupling, preamplifier decoupling and sample loading. SNR for the 16 channel coil was ∼ 1.5 times that of the commercial coil in the human occipital lobe, and showed better g-factor values for accelerated imaging. fMRI tests conducted showed better response to Blood Oxygen Level Dependent (BOLD) activation, at resolutions of 1.2mm and 0.8mm isotropic. The 4 channel phased array transmit coil provides homogeneous excitation across the visual cortex, which, in combination with the dual row 16 channel receive array, makes for a valuable research tool for high resolution anatomical and functional imaging of the visual cortex at 7T.

  6. Cooling and dehumidifying coils

    International Nuclear Information System (INIS)

    Murthy, M.V.K.

    1988-01-01

    The operating features of cooling and dehumidifying coils and their constructional details are discussed. The heat transfer relations as applicable to the boiling refrigerant and a single phase fluid are presented. Methods of accounting for the effect of moisture condensation on the air side heat transfer coefficient and the fin effectiveness are explained. The logic flow necessary to analyze direct expansion coils and chilled water coils is discussed

  7. The JET divertor coil

    International Nuclear Information System (INIS)

    Last, J.R.; Froger, C.; Sborchia, C.

    1989-01-01

    The divertor coil is mounted inside the Jet vacuum vessel and is able to carry 1 MA turns. It is of conventional construction - water cooled copper, epoxy glass insulation -and is contained in a thin stainless steel case. The coil has to be assembled, insulated and encased inside the Jet vacuum vessel. A description of the coil is given, together with technical information (including mechanical effects on the vacuum vessel), an outline of the manufacture process and a time schedule. (author)

  8. Physiological Studies on Pea Tendrils. IV. Flavonoids and Contact Coiling

    Science.gov (United States)

    Jaffe, M. J.; Galston, A. W.

    1967-01-01

    Pea tendrils contain high concentrations of flavonoids, mainly quercetin-triglucosyl-p-coumarate (QGC). QGC is most abundant near the highly responsive apex of the tendril, and least abundant at the base. After mechanical stimulation, and during coiling of the tendril, the QGC titer drops to about 30% of its original value. The kinetics of flavonoid disappearance are significantly correlated with the kinetics of coiling. Aqueous extracts of unstimulated pea tendrils or 10 μm QGC inhibit contact coiling of excised tendrils. Extracts of coiled tendrils do not. The evidence indicates a possible regulatory role for flavonoids in contact coiling. PMID:16656581

  9. Misalignment tolerable coil structure for biomedical applications with wireless power transfer.

    Science.gov (United States)

    Chow, Jeff P W; Chen, Nan; Chung, Henry S H; Chan, Leanne L H

    2013-01-01

    Coil-misalignment is one of the major hurdles for inductively coupled wireless power transfer in applications like retinal prosthesis. Weak magnetic flux linkage due to coil misalignments would significantly impair the power efficiency. A novel receiver configuration with high misalignment tolerance is presented in this paper. The proposed receiver is composed of two receiver coils placed orthogonally, so as to reduce the variation of mutual inductance between transmitting and receiving coils under misalignment conditions. Three different receiver coil structures are analyzed and compared using the same length of wire. Theoretical predictions have been confirmed with measurement results.

  10. The experimental study on positioning of the surface coil for magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Matsumoto, Kyoji; Yotsui, Yoritaka; Koseki, Yonoshin [Osaka Dental Univ., Hirakata (Japan)

    2002-12-01

    We examined the correlation between signal intensity and setting angulations for magnetic resonance imagesobtained using a surface coil, which had a three inch surface coil, and dual coil, which and a three inch surface coil and an anterior neck coil. We took T2-3D weighted, T2-2D weighted and T1-2D weighted images with the angulated three-inch surface coil at 0-90 degrees with the magnetic direction. In every sequence, the maximum intensity with the dual coil was taken with angulations of 50-60 degrees. The intensity of the dual coil could be as much as the three times that of the single coil. As the angulations increased with the dual coil, the thickness of the effective intensity was decreased until it reached 50% of the maximum thickness. With the single coil it decreased until it reached 10%. When using a high-resolution coil that cannot be setup parallel with the magnetic direction, we recommend using a dual coil rather than a single coil to increase the signal intensity. In the oral cavity, the intraoral coil should be used with the extraoral coil as the phased array coil. This is the optimum condition of coil angulation for taking high resolution images. (author)

  11. [Development of RF coil of permanent magnet mini-magnetic resonance imager and mouse imaging experiments].

    Science.gov (United States)

    Hou, Shulian; Xie, Huantong; Chen, Wei; Wang, Guangxin; Zhao, Qiang; Li, Shiyu

    2014-10-01

    In the development of radio frequency (RF) coils for better quality of the mini-type permanent magnetic resonance imager for using in the small animal imaging, the solenoid RF coil has a special advantage for permanent magnetic system based on analyses of various types.of RF coils. However, it is not satisfied for imaging if the RF coils are directly used. By theoretical analyses of the magnetic field properties produced from the solenoid coil, the research direction was determined by careful studies to raise further the uniformity of the magnetic field coil, receiving coil sensitivity for signals and signal-to-noise ratio (SNR). The method had certain advantages and avoided some shortcomings of the other different coil types, such as, birdcage coil, saddle shaped coil and phased array coil by using the alloy materials (from our own patent). The RF coils were designed, developed and made for keeled applicable to permanent magnet-type magnetic resonance imager, multi-coil combination-type, single-channel overall RF receiving coil, and applied for a patent. Mounted on three instruments (25 mm aperture, with main magnetic field strength of 0.5 T or 1.5 T, and 50 mm aperture, with main magnetic field strength of 0.48 T), we performed experiments with mice, rats, and nude mice bearing tumors. The experimental results indicated that the RF receiving coil was fully applicable to the permanent magnet-type imaging system.

  12. Exploring the conserved water site and hydration of a coiled-coil trimerisation motif: a MD simulation study.

    Science.gov (United States)

    Dolenc, Jozica; Baron, Riccardo; Missimer, John H; Steinmetz, Michel O; van Gunsteren, Wilfred F

    2008-07-21

    The solvent structure and dynamics around ccbeta-p, a 17-residue peptide that forms a parallel three-stranded alpha-helical coiled coil in solution, was analysed through 10 ns explicit solvent molecular dynamics (MD) simulations at 278 and 330 K. Comparison with two corresponding simulations of the monomeric form of ccbeta-p was used to investigate the changes of hydration upon coiled-coil formation. Pronounced peaks in the solvent density distribution between residues Arg8 and Glu13 of neighbouring helices show the presence of water bridges between the helices of the ccbeta-p trimer; this is in agreement with the water sites observed in X-ray crystallography experiments. Interestingly, this water site is structurally conserved in many three-stranded coiled coils and, together with the Arg and Glu residues, forms part of a motif that determines three-stranded coiled-coil formation. Our findings show that little direct correlation exists between the solvent density distribution and the temporal ordering of water around the trimeric coiled coil. The MD-calculated effective residence times of up to 40 ps show rapid exchange of surface water molecules with the bulk phase, and indicate that the solvent distribution around biomolecules requires interpretation in terms of continuous density distributions rather than in terms of discrete molecules of water. Together, our study contributes to understanding the principles of three-stranded coiled-coil formation.

  13. Active internal corrector coils

    International Nuclear Information System (INIS)

    Thompson, P.A.; Cottingham, J.; Dahl, P.

    1986-01-01

    Trim or corrector coils to correct main magnet field errors and provide higher multipole fields for beam optics purposes are a standard feature of superconducting magnet accelerator systems. This paper describes some of the design and construction features of powered internal trim coils and a sampling of the test results obtained

  14. Compact stellarator coils

    International Nuclear Information System (INIS)

    Pomphrey, N.; Berry, L.A.; Boozer, A.H.

    2001-01-01

    Experimental devices to study the physics of high-beta (β>∼4%), low aspect ratio (A<∼4.5) stellarator plasmas require coils that will produce plasmas satisfying a set of physics goals, provide experimental flexibility, and be practical to construct. In the course of designing a flexible coil set for the National Compact Stellarator Experiment, we have made several innovations that may be useful in future stellarator design efforts. These include: the use of Singular Value Decomposition methods for obtaining families of smooth current potentials on distant coil winding surfaces from which low current density solutions may be identified; the use of a Control Matrix Method for identifying which few of the many detailed elements of the stellarator boundary must be targeted if a coil set is to provide fields to control the essential physics of the plasma; the use of Genetic Algorithms for choosing an optimal set of discrete coils from a continuum of potential contours; the evaluation of alternate coil topologies for balancing the tradeoff between physics objective and engineering constraints; the development of a new coil optimization code for designing modular coils, and the identification of a 'natural' basis for describing current sheet distributions. (author)

  15. Liquid rope coiling

    NARCIS (Netherlands)

    Ribe, N.M.; Habibi, M.; Bonn, D.

    2012-01-01

    A thin stream or rope of viscous fluid falling from a sufficient height onto a surface forms a steadily rotating helical coil. Tabletop laboratory experiments in combination with a numerical model for slender liquid ropes reveal that finite-amplitude coiling can occur in four distinct regimes

  16. Transmit coil design for Wireless Power Transfer for medical implants.

    Science.gov (United States)

    Lemdiasov, Rosti; Venkatasubramanian, Arun

    2017-07-01

    A new design approach for the design of transmit coils for Wireless Power Transfer (WPT) is presented. The theoretical formulation involves a figure of merit that has to be maximized to solve for the surface current. Numerical predictions and comparisons with practical measurements for the coil parameters (inductance. resistance) underscore the success of this approach in terms of achieving strong coupling with a receive coil while maintaining low resistance.

  17. Large coil task and results of testing US coils

    International Nuclear Information System (INIS)

    Haubenreich, P.N.

    1986-01-01

    The United States, EURATOM, Japan, and Switzerland have collaborated since 1978 in development of superconducting toroidal field coils for fusion reactor applications. The United States provided a test facility nd three coils; the other participants, one coil each. All coils have the same interface dimensions and performance requirements (stable at 8 T), but internal design was decided by each team. Two US coil teams chose bath-cooled NbTi, 10-kA conductors. One developed a Nb 3 Sn conductor, cooled by internal flow, rated at 18 kA. All US coils have diagnostic instrumentation and imbedded heaters that enable stability tests and simulated nuclear heating experiments. In single-coil tests, each coil operated at full current in self-field (6.4 T). In six-coil tests that began in July 1986, one US coil and the Japanese coil hve been successfully operated at full current at 8 T. The other coils have operated as background coils while awaiting their turn as test coil. Coil tests have been informative and results gratifying. The facility has capably supported coil testing and its operation has provided information that will be useful in designing future fusion systems. Coil capabilities beyond nominal design points will be determined

  18. Commercial applications for COIL

    Science.gov (United States)

    Solomon, Wayne C.; Carroll, David L.; King, D. M.; Fockler, L. A.; Stromberg, D. S.; Sexauer, M.; Milmoe, A.; Sentman, Lee H.

    2000-01-01

    The chemical oxygen-iodine laser (COIL) is a high power, fiber deliverable tool, which can be used for a number of different industrial applications. COIL is of particular interest because of its short fiber deliverable wavelength, high scaleable continuous wave power, and excellent material interaction properties. In past research the University of Illinois at Urbana-Champaign identified and decommissioning and decontamination (DD) of nuclear facilities as a primary focus for COIL technology. DD will be a major challenge in the coming decades. The use of a robotically driven fiber delivered cutting/ablation tool in contaminated areas promises to lower risks to workers for the DD mission. Further, the high cutting speed of COIL will significantly reduce the time required to cut contaminated equipment, reducing costs. The high power of COIL will permit the dismantling of thick stacks of piping and equipment as well as reactor vessels. COIL is very promising for the removal of material from contaminated surfaces, perhaps to depths thicker than an inch. Laser cutting and ablation minimizes dust and fumes, which reduces the required number of high efficiency particulate accumulator filters, thus reducing costly waste disposal. Other potential industrial applications for COIL are shipbuilding, automotive manufacturing, heavy machinery manufacturing, tasks requiring underwater cutting or welding, and there appear to be very promising applications for high powers lasers in the oil industry.

  19. Open coil traction system.

    Science.gov (United States)

    Vibhute, Pavankumar Janardan

    2012-01-01

    Sliding mechanics have become a popular method for space closure, with the development of preadjusted edgewise appliances. Furthermore, various space closing auxiliaries have been developed and extensively evaluated for their clinical efficiency. Their effectiveness is enhanced with optimum force magnitude and low load deflection rate/force decay. With the advent of nickel-titanium (Ni-Ti) springs in orthodontics, load deflection rates have been markedly reduced. To use Ni-Ti springs, clinicians have to depend upon prefabricated closed coil springs. The open coil traction system, or open coil retraction spring, is developed utilizing Ni-Ti open coil springs for orthodontic space closure. This article describes the fabrication and clinical application of the open coil traction system, which has a number of advantages. It sustains a low load deflection rate with optimum force magnitude, and its design is adjustable for a desired length and force level. It is fail-safe for both activation and deactivation (ie, it cannot be overactivated, and the decompression limit of the open coil is controlled by the operator). The open coil traction system can be offset from the mucosa to help reduce soft tissue impingement.

  20. Coil spring venting arrangement

    International Nuclear Information System (INIS)

    McCugh, R.M.

    1975-01-01

    A simple venting device for trapped gas pockets in hydraulic systems is inserted through a small access passages, operated remotely, and removed completely. The device comprises a small diameter, closely wound coil spring which is pushed through a guide temporarily inserted in the access passage. The guide has a central passageway which directs the coil spring radially upward into the pocket, so that, with the guide properly positioned for depth and properly oriented, the coil spring can be pushed up into the top of the pocket to vent it. By positioning a seal around the free end of the guide, the spring and guide are removed and the passage is sealed

  1. Extending the self-assembly of coiled-coil hybrids

    NARCIS (Netherlands)

    Robson Marsden, Hana

    2009-01-01

    Of the various biomolecular building blocks in use in nature, coiled-coil forming peptides are amongst those with the most potential as building blocks for the synthetic self-assembly of nanostructures. Native coiled coils have the ability to function in, and influence, complex systems composed of

  2. A periodic table of coiled-coil protein structures.

    Science.gov (United States)

    Moutevelis, Efrosini; Woolfson, Derek N

    2009-01-23

    Coiled coils are protein structure domains with two or more alpha-helices packed together via interlacing of side chains known as knob-into-hole packing. We analysed and classified a large set of coiled-coil structures using a combination of automated and manual methods. This led to a systematic classification that we termed a "periodic table of coiled coils," which we have made available at http://coiledcoils.chm.bris.ac.uk/ccplus/search/periodic_table. In this table, coiled-coil assemblies are arranged in columns with increasing numbers of alpha-helices and in rows of increased complexity. The table provides a framework for understanding possibilities in and limits on coiled-coil structures and a basis for future prediction, engineering and design studies.

  3. LHC bending magnet coil

    CERN Multimedia

    A short test version of coil of wire used for the LHC dipole magnets. The high magnetic fields needed for guiding particles around the Large Hadron Collider (LHC) ring are created by passing 12’500 amps of current through coils of superconducting wiring. At very low temperatures, superconductors have no electrical resistance and therefore no power loss. The LHC is the largest superconducting installation ever built. The magnetic field must also be extremely uniform. This means the current flowing in the coils has to be very precisely controlled. Indeed, nowhere before has such precision been achieved at such high currents. Magnet coils are made of copper-clad niobium–titanium cables — each wire in the cable consists of 9’000 niobium–titanium filaments ten times finer than a hair.

  4. On modular stellarator reactor coils

    International Nuclear Information System (INIS)

    Rau, F.; Harmeyer, E.; Kisslinger, J.; Wobig, H.

    1985-01-01

    Modular twisted coils are discussed which produce magnetic fields of the Advanced Stellarator WENDELSTEIN VII-AS type. Reducing the number coils/FP offers advantage for maintenance of coils, but increases the magnetic ripple and B m /B o . Computation of force densities within the coils of ASR and ASB yield local maximum values of about 80 and 180 MN/m 3 , respectively. A system of mutual coil support is being developed. Twisted coils in helical arrangement provide a reactor-sized HELIAC system. In order to reduce the magnetic ripple, a large number of 14 coils/FP in special arrangement is used

  5. TFTR toroidal field coil design

    International Nuclear Information System (INIS)

    Smith, G.E.; Punchard, W.F.B.

    1977-01-01

    The design of the Tokamak Fusion Test Reactor (TFTR) Toroidal Field (TF) magnetic coils is described. The TF coil is a 44-turn, spiral-wound, two-pancake, water-cooled configuration which, at a coil current of 73.3 kiloamperes, produces a 5.2-Tesla field at a major radius of 2.48 meters. The magnetic coils are installed in titanium cases, which transmit the loads generated in the coils to the adjacent supporting structure. The TFTR utilizes 20 of these coils, positioned radially at 18 0 intervals, to provide the required toroidal field. Because it is very highly loaded and subject to tight volume constraints within the machine, the coil presents unique design problems. The TF coil requirements are summarized, the coil configuration is described, and the problems highlighted which have been encountered thus far in the coil design effort, together with the development tests which have been undertaken to verify the design

  6. NCSX Toroidal Field Coil Design

    International Nuclear Information System (INIS)

    Kalish M; Rushinski J; Myatt L; Brooks A; Dahlgren F; Chrzanowski J; Reiersen W; Freudenberg K.

    2005-01-01

    The National Compact Stellarator Experiment (NCSX) is an experimental device whose design and construction is underway at the Department of Energy's Princeton Plasma Physics Laboratory (PPPL). The primary coil systems for the NCSX device consist of the twisted plasma-shaping Modular Coils, the Poloidal Field Coils, and the Toroidal Field (TF) Coils. The TF Coils are D-shaped coils wound from hollow copper conductor, and vacuum impregnated with a glass-epoxy resin system. There are 18 identical, equally spaced TF coils providing 1/R field at the plasma. They operate within a cryostat, and are cooled by LN2, nominally, to 80K. Wedge shaped castings are assembled to the inboard face of these coils, so that inward radial loads are reacted via the nesting of each of the coils against their adjacent partners. This paper outlines the TF Coil design methodology, reviews the analysis results, and summarizes how the design and analysis support the design requirements

  7. Coil protection calculator for TFTR

    International Nuclear Information System (INIS)

    Marsala, R.J.; Woolley, R.D.

    1987-01-01

    A new coil protection calculator (CPC) is presented in this paper. It is now being developed for TFTR's magnetic field coils will replace the existing coil fault detector. The existing fault detector sacrifices TFTR operating capability for simplicity. The new CPC will permit operation up to the actual coil limits by accurately and continuously computing coil parameters in real-time. The improvement will allow TFTR to operate with higher plasma currents and will permit the optimization of pulse repetition rates

  8. An 8/15-channel Tx/Rx head neck RF coil combination with region-specific B1 + shimming for whole-brain MRI focused on the cerebellum at 7T.

    Science.gov (United States)

    Pfaffenrot, Viktor; Brunheim, Sascha; Rietsch, Stefan H G; Koopmans, Peter J; Ernst, Thomas M; Kraff, Oliver; Orzada, Stephan; Quick, Harald H

    2018-02-09

    To design and evaluate an 8/15-channel transmit/receive (Tx/Rx) head-neck RF coil combination with region-specific B1+ shimming for whole-brain MRI with focus on improved functional MRI of the cerebellum at 7 T. An 8-channel transceiver RF head coil was combined with a 7-channel receive-only array. The noise parameters and acceleration capabilities of this 8Tx/15Rx coil setup were compared with a commercially available 1Tx/32Rx RF head coil. Region-specific 8-channel B1+ shimming was applied when using the 8Tx/15Rx RF coil. To evaluate the capability for functional MRI of the cerebellum, temporal SNR and statistical nonparametric maps for finger-tapping experiments with 14 healthy subjects were derived by applying a variable slice thickness gradient-echo echo-planar functional MRI sequence. The 8Tx/15Rx setup had a lower maximum noise correlation between channels, but higher average correlations compared with the 1Tx/32Rx coil. Both RF coils exhibited identical g-factors in the cerebellum with R = 3 acceleration. The enlarged FOV of the 8Tx/15Rx coil in combination with region-specific B1+ shimming increased homogeneity of the transmission field and temporal SNR in caudal cerebellar regions. Temporal SNR losses in cranial parts were reduced, resulting in more highly significant voxels in the caudally activated areas and identical patterns in the cranial cerebellar parts during a finger-tapping task. Compared with the 1Tx/32Rx RF coil, the presented 8Tx/15Rx RF coil combination successfully improves functional MRI of the human cerebellum at 7 T while maintaining whole-brain coverage. A clear temporal SNR gain in caudal cerebellar regions is shown. © 2018 International Society for Magnetic Resonance in Medicine.

  9. Vehicle to wireless power transfer coupling coil alignment sensor

    Science.gov (United States)

    Miller, John M.; Chambon, Paul H.; Jones, Perry T.; White, Clifford P.

    2016-02-16

    A non-contacting position sensing apparatus includes at least one vehicle-mounted receiver coil that is configured to detect a net flux null when the vehicle is optimally aligned relative to the primary coil in the charging device. Each of the at least one vehicle-mounted receiver coil includes a clockwise winding loop and a counterclockwise winding loop that are substantially symmetrically configured and serially connected to each other. When the non-contacting position sensing apparatus is located directly above the primary coil of the charging device, the electromotive forces from the clockwise winding loop and the counterclockwise region cancel out to provide a zero electromotive force, i.e., a zero voltage reading across the coil that includes the clockwise winding loop and the counterclockwise winding loop.

  10. Superconducting coil protection

    International Nuclear Information System (INIS)

    Woods, E.L.

    1975-01-01

    The protection system is based on a two-phase construction program. Phase I is the development of a reliable hardwired relay control system with a digital loop utilizing firmware and a microprocessor controller. Phase II is an expansion of the digital loop to include many heretofore unmonitored coil variables. These new monitored variables will be utilized to establish early quench detection and to formulate confirmation techniques of the quench detection mechanism. Established quench detection methods are discussed and a new approach to quench detection is presented. The new circuit is insensitive to external pulsed magnetic fields and the associated induced voltages. Reliability aspects of the coil protection system are discussed with respect to shutdowns of superconducting coil systems. Redundance and digital system methods are presented as related topics

  11. NET model coil test possibilities

    International Nuclear Information System (INIS)

    Erb, J.; Gruenhagen, A.; Herz, W.; Jentzsch, K.; Komarek, P.; Lotz, E.; Malang, S.; Maurer, W.; Noether, G.; Ulbricht, A.; Vogt, A.; Zahn, G.; Horvath, I.; Kwasnitza, K.; Marinucci, C.; Pasztor, G.; Sborchia, C.; Weymuth, P.; Peters, A.; Roeterdink, A.

    1987-11-01

    A single full size coil for NET/INTOR represents an investment of the order of 40 MUC (Million Unit Costs). Before such an amount of money or even more for the 16 TF coils is invested as much risks as possible must be eliminated by a comprehensive development programme. In the course of such a programme a coil technology verification test should finally prove the feasibility of NET/INTOR TF coils. This study report is almost exclusively dealing with such a verification test by model coil testing. These coils will be built out of two Nb 3 Sn-conductors based on two concepts already under development and investigation. Two possible coil arrangements are discussed: A cluster facility, where two model coils out of the two Nb 3 TF-conductors are used, and the already tested LCT-coils producing a background field. A solenoid arrangement, where in addition to the two TF model coils another model coil out of a PF-conductor for the central PF-coils of NET/INTOR is used instead of LCT background coils. Technical advantages and disadvantages are worked out in order to compare and judge both facilities. Costs estimates and the time schedules broaden the base for a decision about the realisation of such a facility. (orig.) [de

  12. Prostate cancer: 1.5 T endo-coil dynamic contrast-enhanced MRI and MR spectroscopy-correlation with prostate biopsy and prostatectomy histopathological data

    DEFF Research Database (Denmark)

    Chabanova, E.; Balslev, I.; Løgager, Vibeke Berg

    2010-01-01

    PURPOSE: To investigate diagnostic accuracy of detection of prostate cancer by magnetic resonance: to evaluate the performance of T2WI, DCEMRI and CSI and to correlate the results with biopsy and radical prostatectomy histopathological data. MATERIALS AND METHODS: 43 patients, scheduled for radical...... techniques and histopathological findings on prostatectomy specimens. RESULTS: Prostate cancer was identified in all 43 patients by combination of the three MR techniques. The detection of prostate cancer on sextant-basis showed sensitivity and specificity: 50% and 91% for TRUS, 72% and 55% for T2WI, 49......% and 69% for DCEMRI, and 46% and 78% for CSI. CONCLUSION: T2WI, DCEMRI and CSI in combination can identify prostate cancer. Further development of MR technologies for these MR methods is necessary to improve the detection of the prostate cancer...

  13. Trim coil power supplies

    International Nuclear Information System (INIS)

    Haisler, R.; Peeler, H.; Zajicek, W.

    1985-01-01

    The 18 trim coil power supplies have been constructed and are now in place in the K500 pit and pit mezzanine. Final wiring of the primary power and control power is proceeding along with installation of cooling water supplies. The supplies are expected to be ready for final testing into resistive loads at the beginning of June, 1985

  14. Correlates of Conduct Problems and Depression Comorbidity in Elementary School Boys and Girls Receiving Special Educational Services

    Science.gov (United States)

    Poirier, Martine; Déry, Michèle; Toupin, Jean; Verlaan, Pierrette; Lemelin, Jean-Pascal; Jagiellowicz, Jadzia

    2015-01-01

    There is limited empirical research on the correlates of conduct problems (CP) and depression comorbidity during childhood. This study investigated 479 elementary school children (48.2% girls). It compared children with comorbidity to children with CP only, depression only, and control children on individual, academic, social, and family…

  15. Eccentric Coil Test Facility (ECTF)

    International Nuclear Information System (INIS)

    Burn, P.B.; Walstrom, P.L.; Anderson, W.C.; Marguerat, E.F.

    1975-01-01

    The conceptual design of a facility for testing superconducting coils under some conditions peculiar to tokamak systems is given. A primary element of the proposed facility is a large 25 MJ background solenoid. Discussions of the mechanical structure, the stress distribution and the thermal stability for this coil are included. The systems for controlling the facility and diagnosing test coil behavior are also described

  16. Modular coils: a promising toroidal-reactor-coil system

    International Nuclear Information System (INIS)

    Chu, T.K.; Furth, H.P.; Johnson, J.L.; Ludescher, C.; Weimer, K.E.

    1981-04-01

    The concept of modular coils originated from a need to find reactor-relevant stellarator windings, but its usefulness can be extended to provide an externally applied, additional rotational transform in tokamaks. Considerations of (1) basic principles of modular coils, (2) types of coils, (3) types of configurations (general, helically symmetric, helically asymmetric, with magnetic well, with magnetic hill), (4) types of rotational transform profile, and (5) structure and origin of ripples are given. These results show that modular coils can offer a wide range of vacuum magnetic field configurations, some of which cannot be obtained with the classical stellarator or torsatron coil configuration

  17. Optimization of Coil Element Configurations for a Matrix Gradient Coil.

    Science.gov (United States)

    Kroboth, Stefan; Layton, Kelvin J; Jia, Feng; Littin, Sebastian; Yu, Huijun; Hennig, Jurgen; Zaitsev, Maxim

    2018-01-01

    Recently, matrix gradient coils (also termed multi-coils or multi-coil arrays) were introduced for imaging and B 0 shimming with 24, 48, and even 84 coil elements. However, in imaging applications, providing one amplifier per coil element is not always feasible due to high cost and technical complexity. In this simulation study, we show that an 84-channel matrix gradient coil (head insert for brain imaging) is able to create a wide variety of field shapes even if the number of amplifiers is reduced. An optimization algorithm was implemented that obtains groups of coil elements, such that a desired target field can be created by driving each group with an amplifier. This limits the number of amplifiers to the number of coil element groups. Simulated annealing is used due to the NP-hard combinatorial nature of the given problem. A spherical harmonic basis set up to the full third order within a sphere of 20-cm diameter in the center of the coil was investigated as target fields. We show that the median normalized least squares error for all target fields is below approximately 5% for 12 or more amplifiers. At the same time, the dissipated power stays within reasonable limits. With a relatively small set of amplifiers, switches can be used to sequentially generate spherical harmonics up to third order. The costs associated with a matrix gradient coil can be lowered, which increases the practical utility of matrix gradient coils.

  18. Supporting device for Toroidal coils

    International Nuclear Information System (INIS)

    Araki, Takao.

    1985-01-01

    Purpose: To reduce the response of a toroidal coil supporting device upon earthquakes and improve the earthquake proofness in a tokamak type thermonuclear device. Constitution: Structural materials having large longitudinal modulus and enduring great stresses, for example, stainless steels are used as the toroidal coil supporting legs and heat insulating structural materials are embedded in a nuclear reactor base mats below the supporting legs. Furthermore, heat insulating concretes are spiked around the heat insulating structural materials to prevent the intrusion of heat to the toroidal coils. The toroidal coils are kept at cryogenic state and superconductive state for the conductors. In this way, the period of proper vibrations of the toroidal coils and the toroidal coil supporting structures can be shortened thereby decreasing the seismic response. Furthermore, since the strength of the supporting legs is increased, the earthquake proofness of the coils can be improved. (Kamimura, M.)

  19. Correlation of free-response and receiver-operating-characteristic area-under-the-curve estimates: Results from independently conducted FROC/ROC studies in mammography

    International Nuclear Information System (INIS)

    Zanca, Federica; Hillis, Stephen L.; Claus, Filip; Van Ongeval, Chantal; Celis, Valerie; Provoost, Veerle; Yoon, Hong-Jun; Bosmans, Hilde

    2012-01-01

    Purpose: From independently conducted free-response receiver operating characteristic (FROC) and receiver operating characteristic (ROC) experiments, to study fixed-reader associations between three estimators: the area under the alternative FROC (AFROC) curve computed from FROC data, the area under the ROC curve computed from FROC highest rating data, and the area under the ROC curve computed from confidence-of-disease ratings. Methods: Two hundred mammograms, 100 of which were abnormal, were processed by two image-processing algorithms and interpreted by four radiologists under the FROC paradigm. From the FROC data, inferred-ROC data were derived, using the highest rating assumption. Eighteen months afterwards, the images were interpreted by the same radiologists under the conventional ROC paradigm; conventional-ROC data (in contrast to inferred-ROC data) were obtained. FROC and ROC (inferred, conventional) data were analyzed using the nonparametric area-under-the-curve (AUC), (AFROC and ROC curve, respectively). Pearson correlation was used to quantify the degree of association between the modality-specific AUC indices and standard errors were computed using the bootstrap-after-bootstrap method. The magnitude of the correlations was assessed by comparison with computed Obuchowski-Rockette fixed reader correlations. Results: Average Pearson correlations (with 95% confidence intervals in square brackets) were: Corr(FROC, inferred ROC) = 0.76[0.64, 0.84] > Corr(inferred ROC, conventional ROC) = 0.40[0.18, 0.58] > Corr (FROC, conventional ROC) = 0.32[0.16, 0.46]. Conclusions: Correlation between FROC and inferred-ROC data AUC estimates was high. Correlation between inferred- and conventional-ROC AUC was similar to the correlation between two modalities for a single reader using one estimation method, suggesting that the highest rating assumption might be questionable.

  20. The correlation between subordinate fish eye colour and received attacks: a negative social feedback mechanism for the reduction of aggression during the formation of dominance hierarchies.

    Science.gov (United States)

    Miyai, Caio A; Carretero Sanches, Fábio H; Costa, Tânia M; Colpo, Karine Delevati; Volpato, Gilson L; Barreto, Rodrigo E

    2011-12-01

    Eye darkening has been linked to social status in fish. The subordinate's eyes darken, while the eyes of the dominant fish become pale. Although this phenomenon has been described in salmonid fishes and in the African cichlid Nile tilapia Oreochromis niloticus, it is unclear whether eye darkening correlates with a reduction in aggressive behaviour. Thus, we evaluated the link between social status and eye darkening. We evaluated whether the eye colours of subordinate fish correlate with the frequency of received attacks in a neotropical fish, the pearl cichlid Geophagus brasiliensis. We paired pearl cichlids and quantified both the aggressive behaviour and the eye darkening of each fish. As has been described for Nile tilapia and Atlantic salmon, a clear-cut hierarchical relationship formed, where dominance and subordination were associated with pale and dark eye colours, respectively. Initially, eye colour darkening was positively correlated with the frequency of received attacks; however, a negative association occurred following eye darkening, in which the intensity of aggressive interactions decreased. Thus, fish that initially received a high number of attacks signalled subordination more rapidly and intensely (rapid and dramatic eye darkening), thereby inducing a negative social feedback mechanism that led to reduced aggression. Copyright © 2011 Elsevier GmbH. All rights reserved.

  1. Locally Advanced Rectal Cancer Patients Receiving Radio-Chemotherapy: A Novel Clinical-Pathologic Score Correlates With Global Outcome

    International Nuclear Information System (INIS)

    Berardi, Rossana; Mantello, Giovanna; Scartozzi, Mario; Del Prete, Stefano; Luppi, Gabriele; Martinelli, Roberto; Fumagalli, Marco; Grillo-Ruggieri, Filippo; Bearzi, Italo; Mandolesi, Alessandra; Marmorale, Cristina; Cascinu, Stefano

    2009-01-01

    Purpose: To determine the importance of downstaging of locally advanced rectal cancer after neoadjuvant treatment. Methods and Materials: The study included all consecutive patients with locally advanced rectal cancer who underwent neoadjuvant treatment (chemotherapy and/or radiotherapy) in different Italian centers from June 1996 to December 2003. A novel score was used, calculated as the sum of numbers obtained by giving a negative or positive point, respectively, to each degree of increase or decrease in clinical to pathologic T and N status. Results: A total of 317 patients were eligible for analysis. Neoadjuvant treatments performed were as follows: radiotherapy alone in 75 of 317 patients (23.7%), radiotherapy plus chemotherapy in 242 of 317 patients (76.3%). Worse disease-free survival was observed in patients with a lower score (Score 1 = -3 to +3 vs. Score 2 = +4 to +7; p = 0.04). Conclusions: Our results suggest that a novel score, calculated from preoperative and pathologic tumor and lymph node status, could represent an important parameter to predict outcome in patients receiving neoadjuvant treatment for rectal cancer. The score could be useful to select patients for adjuvant chemotherapy after neoadjuvant treatment and surgery.

  2. Analysis and experimental study of wireless power transfer with HTS coil and copper coil as the intermediate resonators system

    Science.gov (United States)

    Wang, Xiufang; Nie, Xinyi; Liang, Yilang; Lu, Falong; Yan, Zhongming; Wang, Yu

    2017-01-01

    Intermediate resonator (repeater) between transmitter and receiver can significantly increase the distance of wireless power transfer (WPT) and the efficiency of wireless power transfer. The wireless power transfer via strongly coupled magnetic resonances with an high temperature superconducting (HTS) coil and copper coil as intermediate resonators was presented in this paper. The electromagnetic experiment system under different conditions with different repeating coils were simulated by finite element software. The spatial distribution patterns of magnetic induction intensity at different distances were plotted. In this paper, we examined transfer characteristics with HTS repeating coil and copper repeating coil at 77 K and 300 K, respectively. Simulation and experimental results show that HTS and copper repeating coil can effectively enhance the space magnetic induction intensity, which has significant effect on improving the transmission efficiency and lengthening transmission distance. We found that the efficiency and the distance of wireless power transfer system with an HTS coil as repeater is much higher by using of copper coil as repeater.

  3. MR imaging of colorectal carcinomas using an MR endoscopic coil

    International Nuclear Information System (INIS)

    Murano, Akihiko; Kido, Choichiro; Sasaki, Fumio; Nakamura, Tsuneya; Kobayashi, Semi; Katoh, Tomoyuki; Hirai, Takashi

    1994-01-01

    Diagnosis of the depth of wall invasion by rectal carcinoma using MR endoscopy was performed in ten resected specimens, including five rectal carcinomas, three colon carcinomas, two normal gastric wall. In addition, the gastric wall of a pig was examined. MR imaging was done with a 1.5-T Signa Advantage (GE Medical System) system, with the surface coil of the MR endoscope acting as the receiver coil. Five layers could be distinguished in the bowel wall: mucosa, submucosa and muscularis propria divided into circular muscle, longitudinal muscle and intervening connective tissue. Tumors had almost the same signal intensity as muscle. The MR images of colon carcinomas, rectal carcinomas, and extrinsically metastatic involvement of the sigmoid colon by rectal carcinoma all correlated well with the pathological findings. The normal structure of the gastric wall was similar to that of the colon. 3D-fast Spoiled Grass (SPGR) sequence has a fairly short scanning time. Thus, the possibility of precise clinical diagnosis by this method was suggested. (author)

  4. Endosphenoidal coil for intraoperative magnetic resonance imaging of the pituitary gland during transsphenoidal surgery.

    Science.gov (United States)

    Chittiboina, Prashant; Talagala, S Lalith; Merkle, Hellmut; Sarlls, Joelle E; Montgomery, Blake K; Piazza, Martin G; Scott, Gretchen; Ray-Chaudhury, Abhik; Lonser, Russell R; Oldfield, Edward H; Koretsky, Alan P; Butman, John A

    2016-12-01

    OBJECTIVE Pituitary MR imaging fails to detect over 50% of microadenomas in Cushing's disease and nearly 80% of cases of dural microinvasion. Surface coils can generate exceptionally high-resolution images of the immediately adjacent tissues. To improve imaging of the pituitary gland, a receive-only surface coil that can be placed within the sphenoid sinus (the endosphenoidal coil [ESC]) during transsphenoidal surgery (TSS) was developed and assessed. METHODS Five cadaver heads were used for preclinical testing of the ESC. The ESC (a double-turn, 12-mm-diameter surface coil made from 1-mm-diameter copper wire) was developed to obtain images in a 1.5-T MR scanner. The ESC was placed (via a standard sublabial TSS approach) on the anterior sella face. Clinical MR scans were obtained using the 8-channel head coil and ESC as the receiver coils. Using the ESC, ultra-high-resolution, 3D, balanced fast field echo (BFFE) and T1-weighted imaging were performed at resolutions of 0.25 × 0.25 × 0.50 mm 3 and 0.15 × 0.15 × 0.30 mm 3 , respectively. RESULTS Region-of-interest analysis indicated a 10-fold increase in the signal-to-noise ratio (SNR) of the pituitary when using the ESC compared with the 8-channel head coil. ESC-related improvements (p anterior pituitary gland surface. High-resolution BFFE MR imaging obtained using ESC revealed a number of anatomical features critical to pituitary surgery that were not visible on 8-channel MR imaging, including the pituitary capsule, the intercavernous sinus, and microcalcifications in the pars intermedia. These ESC imaging findings were confirmed by the pathological correlation with whole-mount pituitary sections. CONCLUSIONS ESC can significantly improve SNR in the sellar region intraoperatively using current 1.5-T MR imaging platforms. Improvement in SNR can provide images of the sella and surrounding structures with unprecedented resolution. Clinical use of this ESC may allow for MR imaging detection of previously occult

  5. Endosphenoidal coil for intraoperative magnetic resonance imaging of the pituitary gland during transsphenoidal surgery

    Science.gov (United States)

    Chittiboina, Prashant; Talagala, S. Lalith; Merkle, Hellmut; Sarlls, Joelle E.; Montgomery, Blake K.; Piazza, Martin G.; Scott, Gretchen; Ray-Chaudhury, Abhik; Lonser, Russell R.; Oldfield, Edward H.; Koretsky, Alan P.; Butman, John A.

    2016-01-01

    OBJECTIVE Pituitary MR imaging fails to detect over 50% of microadenomas in Cushing’s disease and nearly 80% of cases of dural microinvasion. Surface coils can generate exceptionally high-resolution images of the immediately adjacent tissues. To improve imaging of the pituitary gland, a receive-only surface coil that can be placed within the sphenoid sinus (the endosphenoidal coil [ESC]) during transsphenoidal surgery (TSS) was developed and assessed. METHODS Five cadaver heads were used for preclinical testing of the ESC. The ESC (a double-turn, 12-mm-diameter surface coil made from 1-mm-diameter copper wire) was developed to obtain images in a 1.5-T MR scanner. The ESC was placed (via a standard sublabial TSS approach) on the anterior sella face. Clinical MR scans were obtained using the 8-channel head coil and ESC as the receiver coils. Using the ESC, ultra–high-resolution, 3D, balanced fast field echo (BFFE) and T1-weighted imaging were performed at resolutions of 0.25 × 0.25 × 0.50 mm3 and 0.15 × 0.15 × 0.30 mm3, respectively. RESULTS Region-of-interest analysis indicated a 10-fold increase in the signal-to-noise ratio (SNR) of the pituitary when using the ESC compared with the 8-channel head coil. ESC-related improvements (p pituitary gland surface. High-resolution BFFE MR imaging obtained using ESC revealed a number of anatomical features critical to pituitary surgery that were not visible on 8-channel MR imaging, including the pituitary capsule, the intercavernous sinus, and microcalcifications in the pars intermedia. These ESC imaging findings were confirmed by the pathological correlation with whole-mount pituitary sections. CONCLUSIONS ESC can significantly improve SNR in the sellar region intraoperatively using current 1.5-T MR imaging platforms. Improvement in SNR can provide images of the sella and surrounding structures with unprecedented resolution. Clinical use of this ESC may allow for MR imaging detection of previously occult pituitary

  6. Device for supporting a toroidal coil in a toroidal type nuclear fusion device

    International Nuclear Information System (INIS)

    Kitazawa, Hakaru; Sato, Hiroshi.

    1975-01-01

    Object: To easily manufacture a center block having a strength sufficient to withstand an electromagnetic force exerted on the center of toroidal of a toroidal coil and to increase its reliability. Structure: In a device for supporting toroidal coils wherein the electromagnetic force exerted on the center of toroidal of a plurality of toroidal coils arranged in toroidal fashion, the contact surface between the toroidal coil and the center block is arranged parallel to the center axis of toroidal so as to receive the electromagnetic force exerted on the center of toroidal of the toroidal coil as the component of force in a radial direction. (Taniai, N.)

  7. Coil Optimization for HTS Machines

    DEFF Research Database (Denmark)

    Mijatovic, Nenad; Jensen, Bogi Bech; Abrahamsen, Asger Bech

    An optimization approach of HTS coils in HTS synchronous machines (SM) is presented. The optimization is aimed at high power SM suitable for direct driven wind turbines applications. The optimization process was applied to a general radial flux machine with a peak air gap flux density of ~3T...... is suitable for which coil segment is presented. Thus, the performed study gives valuable input for the coil design of HTS machines ensuring optimal usage of HTS tapes....

  8. Design and testing of a coil-unit barrel for helical coil electromagnetic launcher

    Science.gov (United States)

    Yang, Dong; Liu, Zhenxiang; Shu, Ting; Yang, Lijia; Ouyang, Jianming

    2018-01-01

    A coil-unit barrel for a helical coil electromagnetic launcher is described. It provides better features of high structural strength and flexible adjustability. It is convenient to replace the damaged coil units and easy to adjust the number of turns in the stator coils due to the modular design. In our experiments, the highest velocity measured for a 4.5-kg projectile is 47.3 m/s and the mechanical reinforcement of the launcher could bear 35 kA peak current. The relationship between the energy conversion efficiency and the inductance gradient of the launcher is also studied. In the region of low inductance gradient, the efficiency is positively correlated with the inductance gradient. However, in the region of high inductance gradient, the inter-turn arc erosion becomes a major problem of limiting the efficiency and velocity of the launcher. This modular barrel allows further studies in the inter-turn arc and the variable inductance gradient helical coil launcher.

  9. Large superconducting coil fabrication development

    International Nuclear Information System (INIS)

    Brown, R.L.; Allred, E.L.; Anderson, W.C.; Burn, P.B.; Deaderick, R.I.; Henderson, G.M.; Marguerat, E.F.

    1975-01-01

    Toroidal fields for some fusion devices will be produced by an array of large superconducting coils. Their size, space limitation, and field requirements dictate that they be high performance coils. Once installed, accessibility for maintenance and repairs is severely restricted; therefore, good reliability is an obvious necessity. Sufficient coil fabrication will be undertaken to develop and test methods that are reliable, fast, and economical. Industrial participation will be encouraged from the outset to insure smooth transition from development phases to production phases. Initially, practice equipment for three meter bore circular coils will be developed. Oval shape coil forms will be included in the practice facility later. Equipment that is more automated will be developed with the expectation of winding faster and obtaining good coil quality. Alternate types of coil construction, methods of winding and insulating, will be investigated. Handling and assembly problems will be studied. All technology developed must be feasible for scaling up when much larger coils are needed. Experimental power reactors may need coils having six meter or larger bores

  10. Triple Halo Coil: Development and Comparison with Other TMS Coils

    Science.gov (United States)

    Rastogi, Priyam; Hadimani, Ravi; Jiles, David

    Transcranial Magnetic Stimulation (TMS) is a non-invasive stimulation technique that can be used for the treatment of various neurological disorders such as Parkinson's Disease, PTSD, TBI and anxiety by regulating synaptic activity. TMS is FDA approved for the treatment of major depressive disorder. There is a critical need to develop deep TMS coils that can stimulate deeper regions of the brain without excessively stimulating the cortex in order to provide an alternative to surgical methods. We have developed a novel multi-coil configuration called ``Triple Halo Coil'' (THC) that can stimulate deep brain regions. Investigation of induced electric and magnetic field in these regions have been achieved by computer modelling. Comparison of the results due to THC configuration have been conducted with other TMS coils such as ``Halo Coil'', circular coil and ``Figure of Eight'' coil. There was an improvement of more than 15 times in the strength of magnetic field, induced by THC configuration at 10 cm below the vertex of the head when compared with the ``Figure of Eight'' coil alone. Carver Charitable Trust.

  11. The coiled coil motif in polymer drug delivery systems

    Czech Academy of Sciences Publication Activity Database

    Pechar, Michal; Pola, Robert

    2013-01-01

    Roč. 31, č. 1 (2013), s. 90-96 ISSN 0734-9750 R&D Projects: GA ČR GA203/08/0543; GA MŠk 1M0505 Institutional research plan: CEZ:AV0Z40500505 Keywords : coiled coil * hydrophilic polymer * recombinant protein Subject RIV: CD - Macromolecular Chemistry Impact factor: 8.905, year: 2013

  12. A novel method for coil efficiency estimation: Validation with a 13C birdcage

    DEFF Research Database (Denmark)

    Giovannetti, Giulio; Frijia, Francesca; Hartwig, Valentina

    2012-01-01

    Coil efficiency, defined as the B1 magnetic field induced at a given point on the square root of supplied power P, is an important parameter that characterizes both the transmit and receive performance of the radiofrequency (RF) coil. Maximizing coil efficiency will maximize also the signal......-to-noise ratio. In this work, we propose a novel method for RF coil efficiency estimation based on the use of a perturbing loop. The proposed method consists of loading the coil with a known resistor by inductive coupling and measuring the quality factor with and without the load. We tested the method...... by measuring the efficiency of a 13C birdcage coil tuned at 32.13 MHz and verified its accuracy by comparing the results with the nuclear magnetic resonance nutation experiment. The method allows coil performance characterization in a short time and with great accuracy, and it can be used both on the bench...

  13. Tumor markers CEA and CA 19-9 correlate with radiological imaging in metastatic colorectal cancer patients receiving first-line chemotherapy.

    Science.gov (United States)

    Michl, M; Koch, J; Laubender, R P; Modest, D P; Giessen, C; Schulz, Ch; Heinemann, V

    2014-10-01

    In patients with metastatic colorectal cancer (mCRC), radiological imaging represents the current standard to evaluate the efficacy of chemotherapy. However, with growing knowledge about tumor biology, other diagnostic tools become of interest which can supplement radiology. The aim of the present study was to examine the correlation of tumor and serum markers with radiological imaging in patients with mCRC receiving first-line therapy. Patients were included if tumor (carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA 19-9)) and serum marker (lactatdehydrogenase (LDH), γ-glutamyltransferase (γGT), alkaline phosphatase (AP), C-reactive protein (CRP), leucocyte count (WBC), hemoglobin (Hb)) levels were available at baseline and at least two times during treatment. The decline and increase of tumor and serum markers over time were approximated for each patient by estimating slopes depending on the radiological assessment. A linear mixed effects multiple regression model for each subject was used to evaluate the intra-class correlation of these slopes modeling tumor and serum marker changes with radiological imaging. Data of 124 patients (41 female, 83 male; median age 62.9 years, range 27-85) who received first-line chemotherapy for mCRC from 11/2007 to 04/2010 were analyzed retrospectively. CEA level slopes (n = 49; slopes = 102) differed between radiologically determined progressive disease (PD) and partial response (PR) (p = 0.005) and between PD and stable disease (SD) (p = 0.042). CA 19-9 level slopes (n = 57; slopes = 127) also showed a significant difference between PD and PR (p = 0.002) and PD and SD (p = 0.058). Furthermore, CRP slopes (n = 62; slopes = 134) differed significantly between PD and PR (p = 0.009). For LDH, ALP, γGT, Hb, and WBC, no correlations were observed. The results indicate the correlation of the tumor markers CEA, CA 19-9, and the serum marker CRP with radiological imaging in

  14. The IEA Large Coil Task

    International Nuclear Information System (INIS)

    Beard, D.S.; Klose, W.; Shimamoto, S.; Vecsey, G.

    1988-01-01

    A multinational program of cooperative research, development, demonstrations, and exchanges of information on superconducting magnets for fusion was initiated in 1977 under an IEA agreement. The first major step in the development of TF magnets was called the Large Coil Task. Participants in LCT were the U.S. DOE, EURATOM, JAERI, and the Departement Federal de l'Interieur of Switzerland. The goals of LCT were to obtain experimental data, to demonstrate reliable operation of large superconducting coils, and to prove design principles and fabrication techniques being considered for the toroidal magnets of thermonuclear reactors. These goals were to be accomplished through coordinated but largely independent design, development, and construction of six test coils, followed by collaborative testing in a compact toroidal test array at fields of 8 T and higher. Under the terms of the IEA Agreement, the United States built and operated the test facility at Oak Ridge and provided three test coils. The other participants provided one coil each. Information on design and manufacturing and all test data were shared by all. The LCT team of each participant included a government laboratory and industrial partners or contractors. The last coil was completed in 1985, and the test assembly was completed in October of that year. Over the next 23 months, the six-coil array was cooled down and extensive testing was performed. Results were gratifying, as tests achieved design-point performance and well beyond. (Each coil reached a peak field of 9 T.) Experiments elucidated coil behavior, delineated limits of operability, and demonstrated coil safety. (orig./KP)

  15. Superconducting poloidal coils for STARFIRE commercial reactor

    International Nuclear Information System (INIS)

    Wang, S.T.; Evans, K. Jr.; Turner, L.R.; Huang, Y.C.; Prater, R.; Alcorn, J.

    1979-01-01

    STARFIRE is considered to be the tenth commercial tokamak power plant. A preliminary design study on its superconducting poloidal coil system is presented. Key features of the design studies are: the elimination of the ohmic heating coil; the trade-off studies of the equilibrium field coil locations; and the development of a conceptual design for the superconducting equilibrium field coils. Described are the 100 kA cryostable conductor design, the coil structure, and evaluation of the coil forces

  16. Power Loss Analysis and Comparison of Segmented and Unsegmented Energy Coupling Coils for Wireless Energy Transfer.

    Science.gov (United States)

    Tang, Sai Chun; McDannold, Nathan J

    2015-03-01

    This paper investigated the power losses of unsegmented and segmented energy coupling coils for wireless energy transfer. Four 30-cm energy coupling coils with different winding separations, conductor cross-sectional areas, and number of turns were developed. The four coils were tested in both unsegmented and segmented configurations. The winding conduction and intrawinding dielectric losses of the coils were evaluated individually based on a well-established lumped circuit model. We found that the intrawinding dielectric loss can be as much as seven times higher than the winding conduction loss at 6.78 MHz when the unsegmented coil is tightly wound. The dielectric loss of an unsegmented coil can be reduced by increasing the winding separation or reducing the number of turns, but the power transfer capability is reduced because of the reduced magnetomotive force. Coil segmentation using resonant capacitors has recently been proposed to significantly reduce the operating voltage of a coil to a safe level in wireless energy transfer for medical implants. Here, we found that it can naturally eliminate the dielectric loss. The coil segmentation method and the power loss analysis used in this paper could be applied to the transmitting, receiving, and resonant coils in two- and four-coil energy transfer systems.

  17. Two-Slotted Surface Coil Array for Magnetic Resonance Imaging at 4 Tesla

    International Nuclear Information System (INIS)

    Solis, S. E.; Hernandez, J. A.; Rodriguez, A. O.; Tomasi, D.

    2008-01-01

    Arrays of antennas have been widely accepted for magnetic resonance imaging applications due to their high signal-to-noise ratio (SNR) over large volumes of interest. A new surface coil based on the magnetron tube and called slotted surface coil, has been recently introduced by our group. This coil design experimentally demonstrated a significant improvement over the circular-shaped coil when used in the receive-only mode. The slotted coils formed a two-sheet structure with a 90 deg. separation and each coil had 6 circular slots. Numerical simulations were performed using the finite element method for this coil design to study the behaviour of the array magnetic field. Then, we developed a two-coil array for brain magnetic resonance imaging to be operated at the resonant frequency of 170 MHz in the transceiver mode. Phantom images were acquired with our coil array and standard pulse sequences on a research-dedicated 4 Tesla scanner. Numerical simulations demonstrated that electromagnetic interaction between the coil elements is negligible, and that the magnetic field showed a good uniformity. In vitro images showed the feasibility of this coil array for standard pulses for high field magnetic resonance imaging

  18. Coil protection calculator for TFTR

    International Nuclear Information System (INIS)

    Marsala, R.J.; Lawson, J.E.; Persing, R.G.; Senko, T.R.; Woolley, R.D.

    1989-01-01

    A new coil protection system (CPS) is being developed to replace the existing TFTR magnetic coil fault detector. The existing fault detector sacrifices TFTR operating capability for simplicity. The new CPS, when installed in October of 1988, will permit operation up to the actual coil stress limits parameters in real-time. The computation will be done in a microprocessor based Coil Protection Calculator (CPC) currently under construction at PPL. THe new CPC will allow TFTR to operate with higher plasma currents and will permit the optimization of pulse repetition rates. The CPC will provide real-time estimates of critical coil and bus temperatures and stresses based on real-time redundant measurements of coil currents, coil cooling water inlet temperature, and plasma current. The critical parameter calculations are compared to prespecified limits. If these limits are reached or exceeded, protection action will be initiated to a hard wired control system (HCS), which will shut down the power supplies. The CPC consists of a redundant VME based microprocessor system which will sample all input data and compute all stress quantities every ten milliseconds. Thermal calculations will be approximated every 10ms with an exact solution occurring every second. The CPC features continuous cross-checking of redundant input signal, automatic detection of internal failure modes, monitoring and recording of calculated results, and a quick, functional verification of performance via an internal test system. (author)

  19. Coil for a nuclear fusion device

    International Nuclear Information System (INIS)

    Kadotani, Kenzo.

    1975-01-01

    Object: To provide a thin nuclear fusion coil having good thermal insulation and insulating properties in which mica and glass materials are wound round conductors subjected to varnish treatment and hardened, which is then sealed into a metallic case along with negative gases of more than two atmospheric pressures. Structure: A plurality of conductors impregnated with varnish are hardened by a rare insulating layer, after which it is coated with a layer of mica not impregnated with varnish and a layer of glass substance and is then received into a metallic case and filled under pressure with negative gases at a pressure more than two atmospheric pressures. (Kamimura, M.)

  20. Magnetic field alignment of coil-coil diblock copolymers and blends via intrinsic chain anisotropy

    Science.gov (United States)

    Rokhlenko, Yekaterina; Majewski, Pawel; Larson, Steven; Yager, Kevin; Gopalan, Padma; Avgeropoulos, Apostolos; Chan, Edwin; Osuji, Chinedum

    Magnetic fields can control alignment of self-assembled soft materials such as block copolymers provided there is a suitably large magnetic susceptibility anisotropy present in the system. Recent results have highlighted the existence of a non-trivial intrinsic anisotropy in coil-coil diblock copolymers, specifically in lamellar-forming PS-b-P4VP, which enables alignment at field strengths of a few tesla in systems lacking mesogenic components. Alignment is predicated on correlation in the orientation of end-end vectors implied by the localization of block junctions at the microdomain interface and is observed on cooling across the order-disorder transition in the presence of the field. For appropriate combinations of field strength and grain size, we can leverage intrinsic chain anisotropy to magnetically direct self-assembly of many non-mesogenic systems, including other coil-coil BCPs like PS-b-PDMS and PS-b-PMMA, blends of BCPs of disparate morphologies and MWs, and blends of BCPs with homopolymers. This is noteworthy as blends of PS-b-P4VP with PEO provide a route to form functional materials such as nanoporous films by dissolution of PEO, or aligned ion conduction materials. We survey these various systems using TEM and in-situ X-ray scattering to study the phase behavior and temperature-, time- and field- dependent dynamics of alignment.

  1. Correlation between Tumor-Infiltrating Lymphocytes and Pathological Response in Locally Advanced Breast Cancer Patients Who Received Neoadjuvant Chemotherapy in H. Adam Malik General Hospital

    Directory of Open Access Journals (Sweden)

    Kamal Basri Siregar

    2017-08-01

    Full Text Available Background: Tumor-infiltrating lymphocytes (TILs are emerging as biomarkers mediating tumor response to treatments. Earlier studies have provided evidence that the level of TILs has prognostic value, particularly in triple-negative and human epidermal growth factor receptor-2-positive breast cancer. Moreover, the level of TILs has been associated with treatment outcome in patients undergoing neoadjuvant chemotherapy, and there is a strong correlation with pathologically complete response. In this study, we analyzed whether changes in TILs take place after neoadjuvant therapy and if they correlate with pathological response to treatment. Patients and Methods: We retrospectively analyzed the specimen slides from the Department of Anatomic Pathology of H. Adam Malik General Hospital during 2011–2015. We identified 51 patients fulfilling the inclusion criteria of this study. The histological sections had already been evaluated by hematoxylin and eosin slides. They were reassessed by our pathologist for the percentage of intratumoral and stromal TILs. The correlation with pathological response of the tumor after neoadjuvant therapy was also studied in these patients. Each case was also defined as high- or low-TIL breast cancer adopting previously validated cutoffs. Results: The mean age of the 51 patients was 49.22 years. The most frequent type of breast cancer histology was invasive ductal breast carcinoma in 49 (96% patients, and there were 2 (4% patients with lobular carcinoma. The histopathological grading for high TILs was grade 1 in 5 patients, grade 2 in 15 patients, and grade 3 in 3 patients. High TILs that had a pathologically complete response were found in 47.8% of patients, and low TILs were found in 28.8%. There was no significant correlation between TILs and pathological response in patients with neoadjuvant chemotherapy (p = 0.157. Conclusions: This research has not been able to demonstrate a significant correlation between TILs and

  2. Improved Decoupling for 13C coil Arrays Using Non-Conventional Matching and Preamplifier Impedance

    DEFF Research Database (Denmark)

    Sanchez, Juan Diego; Johansen, Daniel Højrup; Hansen, Rie Beck

    In this study, we describe a method to obtain improved preamplifier decoupling for receive-only coils. The method relies on the better decoupling obtained when coils are matched to an impedance higher than 50 . Preamplifiers with inductive imaginary impedance and low real impedance, increase...

  3. Coil for LEAR extraction septum

    CERN Multimedia

    CERN PhotoLab

    1982-01-01

    Which way does the current flow ? This intriguing object is the coil for the LEAR extraction septum. There were two septa, first a thin one, then this one, not so thin, somewhat on the borderline between septum and bending magnet.

  4. First coil for the SC

    CERN Multimedia

    CERN PhotoLab

    1955-01-01

    The coils for the SC magnet were stored in the large hangar of the Cointrin Airport (to make sure that they would be available before snow and ice would block the roads and canals from Belgium, where they were built).

  5. Books Received

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. Books Received. Articles in Resonance – Journal of Science Education. Volume 1 Issue 1 January 1996 pp 118-118 Books Received. Books Received · More Details Fulltext PDF. Volume 1 Issue 2 February 1996 pp 120-120 Books Received. Books Received.

  6. Radiation resistant ducted superconductive coil

    International Nuclear Information System (INIS)

    Schleich, A.

    1976-01-01

    The radiation-resistant ducted superconductive coil consists of a helically wound electrical conductor constituted by an electrically conductive core of superconductive material provided with a longitudinally extending cooling duct. The core is covered with a layer of inorganic insulating material and the duct is covered by an electrically conductive metallic gas-tight sheath. The metallic sheaths on adjacent turns of the coil are secured together. 2 Claims, 4 Drawing Figures

  7. The Swiss LCT-coil

    International Nuclear Information System (INIS)

    Vecsey, G.; Benz, H.; Horvath, I.

    1985-01-01

    With delivery of the coil to ORNL on February 4, 1984, the second phase of the Swiss Large Coil Program - design and construction - was terminated. Mainlines of the Swiss design concept are summarized and related to theoretical calculations, experimental results of the supporting program, fabricational experience and first successful test results. An attempt is made to draw preliminary conclusions with regard to the design of future toroidal systems such as NET

  8. The SMES model coil. Fabrication

    International Nuclear Information System (INIS)

    Hanai, Satoshi; Nakamoto, Kazunari; Takahashi, Nobuji

    1998-01-01

    A SMES model coil was fabricated as R and D item in the development of component technologies for a 480 MJ/20 MW SMES pilot plant. The coil consists of four double-pancake windings. The coil is the same diameter but half the number of pancakes that will be needed for a SMES pilot plant. The NbTi cable-in-conduit conductor and superconducting joints between the double pancakes are cooled by a forced flow of supercritical helium. Prior to fabrication, various characteristics of the cable-in-conduit were measured by full-sized short samples from actual conductors and by scaled short samples from scaled conductors. The critical current of the scaled short samples was in agreement with that calculated from one strand of the conductor. The impedance between arbitrary dual-oxide coated strands in the full-size conductor was measured to be smaller than that obtained from two Cr-plated strands, which showed a good degree of stability in another coil. It was estimated that oxide-coated conductors would have high stability. Through fabrication of a model coil, it was demonstrated that a large forced-flow coil for a small-scale 100 kWh SMES device could be manufactured. (author)

  9. The SMES model coil. Fabrication

    Energy Technology Data Exchange (ETDEWEB)

    Hanai, Satoshi; Nakamoto, Kazunari; Takahashi, Nobuji [Toshiba Corp., Yokohama, Kanagawa (Japan)] [and others

    1998-07-01

    A SMES model coil was fabricated as R and D item in the development of component technologies for a 480 MJ/20 MW SMES pilot plant. The coil consists of four double-pancake windings. The coil is the same diameter but half the number of pancakes that will be needed for a SMES pilot plant. The NbTi cable-in-conduit conductor and superconducting joints between the double pancakes are cooled by a forced flow of supercritical helium. Prior to fabrication, various characteristics of the cable-in-conduit were measured by full-sized short samples from actual conductors and by scaled short samples from scaled conductors. The critical current of the scaled short samples was in agreement with that calculated from one strand of the conductor. The impedance between arbitrary dual-oxide coated strands in the full-size conductor was measured to be smaller than that obtained from two Cr-plated strands, which showed a good degree of stability in another coil. It was estimated that oxide-coated conductors would have high stability. Through fabrication of a model coil, it was demonstrated that a large forced-flow coil for a small-scale 100 kWh SMES device could be manufactured. (author)

  10. Equilibrium field coil concepts for INTOR

    International Nuclear Information System (INIS)

    Strickler, D.J.; Peng, Y.K.M.; Brown, T.G.

    1981-08-01

    Methods are presented for reducing ampere-turn requirements in the EF coil system. It is shown that coil currents in an EF coil system external to the toroidal field coils can be substantially reduced by relaxing the triangularity of a D-shaped plasma. Further reductions are realized through a hybrid EF coil system using both internal and external coils. Equilibrium field coils for a poloidally asymmetric, single-null INTOR configuration are presented. It is shown that the shape of field lines in the plasma scrapeoff region and divertor channel improves as triangularity is reduced, but it does so at the possible expense of achievable stable beta values

  11. Depletion-Mode GaN HEMT Q-Spoil Switches for MRI Coils.

    Science.gov (United States)

    Lu, Jonathan Y; Grafendorfer, Thomas; Zhang, Tao; Vasanawala, Shreyas; Robb, Fraser; Pauly, John M; Scott, Greig C

    2016-12-01

    Q-spoiling is the process of decoupling an MRI receive coil to protect the equipment and patient. Conventionally, Q-spoiling is performed using a PIN diode switch that draws significant current. In this work, a Q-spoiling technique using a depletion-mode Gallium Nitride HEMT device was developed for coil detuning at both 1.5 T and 3 T MRI. The circuits with conventional PIN diode Q-spoiling and the GaN HEMT device were implemented on surface coils. SNR was measured and compared for all surfaces coils. At both 1.5 T and 3 T, comparable SNR was achieved for all coils with the proposed technique and conventional Q-spoiling. The GaN HEMT device has significantly reduced the required power for Q-spoiling. The GaN HEMT device also provides useful safety features by detuning the coil when unpowered.

  12. A 16-channel MR coil for simultaneous PET/MR imaging in breast cancer

    International Nuclear Information System (INIS)

    Dregely, Isabel; Lanz, Titus; Mueller, Matthias F.; Metz, Stephan; Kuschan, Marika; Nimbalkar, Manoj; Ziegler, Sibylle I.; Nekolla, Stephan G.; Schwaiger, Markus; Bundschuh, Ralph A.; Haase, Axel

    2015-01-01

    To implement and evaluate a dedicated receiver array coil for simultaneous positron emission tomography/magnetic resonance (PET/MR) imaging in breast cancer. A 16-channel receiver coil design was optimized for simultaneous PET/MR imaging. To assess MR performance, the signal-to-noise ratio, parallel imaging capability and image quality was evaluated in phantoms, volunteers and patients and compared to clinical standard protocols. For PET evaluation, quantitative 18 F-FDG PET images of phantoms and seven patients (14 lesions) were compared to images without the coil. In PET image reconstruction, a CT-based template of the coil was combined with the MR-acquired attenuation correction (AC) map of the phantom/patient. MR image quality was comparable to clinical MR-only examinations. PET evaluation in phantoms showed regionally varying underestimation of the standardised uptake value (SUV; mean 22 %) due to attenuation caused by the coil. This was improved by implementing the CT-based coil template in the AC (<2 % SUV underestimation). Patient data indicated that including the coil in the AC increased the SUV values in the lesions (21 ± 9 %). Using a dedicated PET/MR breast coil, state-of-the-art MRI was possible. In PET, accurate quantification and image homogeneity could be achieved if a CT-template of this coil was included in the AC for PET image reconstruction. (orig.)

  13. Endovascular rescue method for undesirably stretched coil.

    Science.gov (United States)

    Cho, Jae Hoon

    2014-10-01

    Undesirable detachment or stretching of coils within the parent artery during aneurysm embolization can be related with thrombus formation, which can be caused occlusion of parent artery or embolic event(s). To escape from this situation, several rescue methods have been reported. A case with undesirably stretched coil in which another rescue method was used, is presented. When the stretched coil is still located in the coil delivery microcatheter, the stretched coil can be removed safely using a snare and a handmade monorail microcatheter. After a snare is lodged in the handmade monorail microcatheter, the snare is introduced over the coil delivery micorcatheter and located in the distal part of the stretched coil. After then, the handmade monorail microcatheter captures the stretched coil and the snare as one unit. This technique using a handmade monorail microcatheter and a snare can be a good rescue modality for the undesirably stretched coil, still remained within the coil delivery microcatheter.

  14. Coil supporting device in nuclear fusion apparatus

    International Nuclear Information System (INIS)

    Hoshi, Ryo; Imura, Yasuya.

    1974-01-01

    Object: To secure intermediate fittings with a coil fixed thereon by an insulating tape to a fixed body by means of fittings, thereby supporting the coil in a narrow space. Structure: A coil is secured to intermediate fittings by means of an insulating tape, after which the intermediate fittings is mounted on a fixed body through fittings to support the coil in a narrow clearance portion between a plasma sealed vessel and a main coil. (Kamimura, M.)

  15. Assessment of the characteristics of MRI coils in terms of RF non-homogeneity using routine spin echo sequences

    International Nuclear Information System (INIS)

    Oghabian, M. A.; Mehdipour, Sh.; RiahicAlam, N.; Rafie, B.; Ghanaati, H.

    2005-01-01

    One of the major causes of image non-uniformity in MRI is due to the existence of non-homogeneity in RF receive and transmit. This can be the most effective source of error in quantitative studies in MRI imaging. Part of this non-homogeneity demonstrates the characteristics of RF coil and part of it is due to the interaction of RF field with the material being imaged. In this study, RF field non-homogeneity of surface and volume coils is measured using an oil phantom. The method employed in this work is based on a routine Spin Echo based sequence as proposed by this group previously. Materials and Methods: For the determination of RF non-uniformity, a method based on Spin Echo sequence (8θ-180) was used as reported previously by the same author. In this method, several images were obtained from one slice using different flip angles while keeping all other imaging parameters constant. Then, signal intensity at a ROI from all of these images were measured and fitted to the MRI defined mathematical model. Since this mathematical model describes the relation between signal intensity and flip angle in a (8θ-180) Spin Echo sequence, it is possible to obtain the variation in receive and transmit sensitivity in terms of the variation of signal intensity from the actual expected values. Since surface coils are functioning as only receiver (RF transmission is done by Body coil), first the results of receive coil homogeneity is measured, then characteristic of transmit coil (for the body coil) is evaluated Results: The coefficient of variation (C.V.) found for T(r) value obtained from images using head coils was in the order of 0.6%. Since the head coil is functioning as both transmitter and receiver, any non-uniformity in either transmit or receive stage can lead to non-homogeneity in RF field. A part from the surface coils, the amount of non-homogeneity due to receive coil was less than that of the transmit coil. In the case of the surface coils the variation in receive

  16. Correlation of degree of hypothyroidism with survival outcomes in patients with metastatic renal cell carcinoma receiving vascular endothelial growth factor receptor tyrosine kinase inhibitors.

    Science.gov (United States)

    Bailey, Erin B; Tantravahi, Srinivas K; Poole, Austin; Agarwal, Archana M; Straubhar, Alli M; Batten, Julia A; Patel, Shiven B; Wells, Chesley E; Stenehjem, David D; Agarwal, Neeraj

    2015-06-01

    Hypothyroidism is a common adverse effect of vascular endothelial growth factor receptor tyrosine kinase inhibitor (VEGFR-TKI) therapy in patients with metastatic renal cell carcinoma (mRCC). Some studies have shown an association with improved survival. However, hypothyroidism severity has not been correlated with survival outcomes. We report the incidence and severity of VEGFR-TKI therapy-associated hypothyroidism in correlation with the survival outcomes of patients with mRCC. A retrospective analysis of patients with mRCC who received VEGFR-TKIs (2004 through 2013) was conducted from a single institutional database. Hypothyroidism, progression-free survival (PFS), and overall survival (OS) were assessed. Univariate and multivariate analyses were performed using the Kaplan-Meier method and Cox proportional hazard models. Of 125 patients with mRCC, 65 were eligible. Their median age was 59 years (range, 45-79 years), and 46 (70.8%) were male. Hypothyroidism occurred in 25 patients (38.5%), of whom 13 had a peak thyroid-stimulating hormone (TSH) level > 10 mIU/L during treatment. The median OS was significantly longer in patients with a peak TSH > 10 mIU/L than in patients with a peak TSH of ≤ 10 mIU/L (not reached vs. 21.4 months, P = .005). On multivariate analysis, risk criteria, number of previous therapies, and severe hypothyroidism (TSH > 10 mIU/L) during VEGFR-TKI therapy remained significant for improvements in PFS and OS. The severity of VEGFR-TKI therapy-associated hypothyroidism (TSH > 10 mIU/L) was associated with improved survival outcomes in patients with mRCC and should not necessitate a dose reduction or therapy discontinuation. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Expression of the DNA repair gene MLH1 correlates with survival in patients who have resected pancreatic cancer and have received adjuvant chemoradiation: NRG Oncology RTOG Study 9704.

    Science.gov (United States)

    Lawrence, Yaacov R; Moughan, Jennifer; Magliocco, Anthony M; Klimowicz, Alexander C; Regine, William F; Mowat, Rex B; DiPetrillo, Thomas A; Small, William; Simko, Jeffry P; Golan, Talia; Winter, Kathryn A; Guha, Chandan; Crane, Christopher H; Dicker, Adam P

    2018-02-01

    The majority of patients with pancreatic cancer who undergo curative resection experience rapid disease recurrence. In previous small studies, high expression of the mismatch-repair protein mutL protein homolog 1 (MLH1) in pancreatic cancers was associated with better outcomes. The objective of this study was to validate the association between MLH1 expression and survival in patients who underwent resection of pancreatic cancer and received adjuvant chemoradiation. Samples were obtained from the NRG Oncology Radiation Therapy Oncology Group 9704 prospective, randomized trial (clinicaltrials.gov identifier NCT00003216), which compared 2 adjuvant protocols in patients with pancreatic cancer who underwent resection. Tissue microarrays were prepared from formalin-fixed, paraffin-embedded, resected tumor tissues. MLH1 expression was quantified using fluorescence immunohistochemistry and automated quantitative analysis, and expression was dichotomized above and below the median value. Immunohistochemical staining was successfully performed on 117 patients for MLH1 (60 and 57 patients from the 2 arms). The characteristics of the participants who had tissue samples available were similar to those of the trial population as a whole. At the time of analysis, 84% of participants had died, with a median survival of 17 months. Elevated MLH1 expression levels in tumor nuclei were significantly correlated with longer disease-free and overall survival in each arm individually and in both arms combined. Two-year overall survival was 16% in patients who had low MLH1 expression levels and 53% in those who had high MLH1 expression levels (P MLH1 expression was correlated with long-term survival. Further studies should assess whether MLH1 expression predicts which patients with localized pancreatic cancer may benefit most from aggressive, multimodality treatment. Cancer 2018;124:491-8. © 2017 American Cancer Society. © 2017 American Cancer Society.

  18. Analytical Model and Optimized Design of Power Transmitting Coil for Inductively Coupled Endoscope Robot.

    Science.gov (United States)

    Ke, Quan; Luo, Weijie; Yan, Guozheng; Yang, Kai

    2016-04-01

    A wireless power transfer system based on the weakly inductive coupling makes it possible to provide the endoscope microrobot (EMR) with infinite power. To facilitate the patients' inspection with the EMR system, the diameter of the transmitting coil is enlarged to 69 cm. Due to the large transmitting range, a high quality factor of the Litz-wire transmitting coil is a necessity to ensure the intensity of magnetic field generated efficiently. Thus, this paper builds an analytical model of the transmitting coil, and then, optimizes the parameters of the coil by enlarging the quality factor. The lumped model of the transmitting coil includes three parameters: ac resistance, self-inductance, and stray capacitance. Based on the exact two-dimension solution, the accurate analytical expression of ac resistance is derived. Several transmitting coils of different specifications are utilized to verify this analytical expression, being in good agreements with the measured results except the coils with a large number of strands. Then, the quality factor of transmitting coils can be well predicted with the available analytical expressions of self- inductance and stray capacitance. Owing to the exact estimation of quality factor, the appropriate coil turns of the transmitting coil is set to 18-40 within the restrictions of transmitting circuit and human tissue issues. To supply enough energy for the next generation of the EMR equipped with a Ø9.5×10.1 mm receiving coil, the coil turns of the transmitting coil is optimally set to 28, which can transfer a maximum power of 750 mW with the remarkable delivering efficiency of 3.55%.

  19. Extended Monopole antenna Array with individual Shield (EMAS) coil: An improved monopole antenna design for brain imaging at 7 tesla MRI.

    Science.gov (United States)

    Woo, Myung-Kyun; Hong, Suk-Min; Lee, Jongho; Kang, Chang-Ki; Park, Sung-Yeon; Son, Young-Don; Kim, Young-Bo; Cho, Zang-Hee

    2016-06-01

    To propose a new Extended Monopole antenna Array with individual Shields (EMAS) coil that improves the B1 field coverage and uniformity along the z-direction. To increase the spatial coverage of Monopole antenna Array (MA) coil, each monopole antenna was shielded and extended in length. Performance of this new coil, which is referred to as EMAS coil, was compared with the original MA coil and an Extended Monopole antenna Array coil with no shield (EMA). For comparison, flip angle, signal-to-noise ratio (SNR), and receive sensitivity maps were measured at multiple regions of interest (ROIs) in the brain. The EMAS coil demonstrated substantially larger flip angle and receive sensitivity than the MA and EMA coils in the inferior aspect of the brain. In the brainstem ROI, for example, the flip angle in the EMAS coil was increased by 45.5% (or 60.0%) and the receive sensitivity was increased by 26.9% (or 14.9%), resulting in an SNR gain of 84.8% (or 76.3%) when compared with the MA coil (or EMA). The EMAS coil provided 25.7% (or 24.4%) more uniform B1+ field distribution compared with the MA (or EMA) coil in sagittal. The EMAS coil successfully extended the imaging volume in lower part of the brain. Magn Reson Med 75:2566-2572, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  20. Correlates of HIV-1 viral suppression in a cohort of HIV-positive drug users receiving antiretroviral therapy in Hanoi, Vietnam

    Science.gov (United States)

    Jordan, Michael R; La, Hanh; Nguyen, Hien Duc; Sheehan, Heidi; Lien, Trinh Thi Minh; Van Dang, Duong; Hellinger, James; Wanke, Christine; Tang, Alice M

    2009-01-01

    Summary Injection drug users bear the burden of HIV in Vietnam and are a focus of national treatment programs. To date, determinants of successful therapy in this population are unknown. Substance use and clinical correlates of viral suppression were studied in 100 HIV-1 infected drug users receiving antiretroviral therapy (ART) for at least 6 months in Hanoi, Vietnam. Mean age of the cohort was 29.9 + 4.9 years; all were men. A majority of patients (73%) achieved viral suppression (HIV-RNA 95% adherence (p<0.01) and current use of trimethoprim/sulfamethoxazole (p<0.01); current or ever diagnosed with tuberculosis was associated with viral non-suppression (p=0.006). Tobacco use was prevalent (84%), and surprisingly 48% of patients reported active drug use; neither was associated with viral non-suppression. This is the first study to document successful ART treatment in a population of Vietnamese drug users; rates of viral suppression are comparable to other international populations. The 28% of patients without HIV-1 suppression highlights the need for adherence promotion, risk reduction programs, and population based surveillance strategies for assessing the emergence of HIV drug resistance in settings where access to viral load and drug resistance testing is limited. PMID:19451329

  1. Assessment of early-stage optic nerve invasion in retinoblastoma using high-resolution 1.5 Tesla MRI with surface coils: a multicentre, prospective accuracy study with histopathological correlation

    Energy Technology Data Exchange (ETDEWEB)

    Brisse, Herve J. [Institut Curie, Department of Radiology, Paris (France); Institut CURIE, Imaging Department, Paris (France); Graaf, Pim de; Rodjan, Firazia; Jong, Marcus C. de; Castelijns, Jonas A. [VU University Medical Center, Department of Radiology, Amsterdam (Netherlands); Galluzzi, Paolo [Neuroimaging and Neurointerventional Unit (NINT) Azienda Ospedaliera e Universitaria Senese, Siena (Italy); Cosker, Kristel; Savignoni, Alexia [Institut Curie, Department of Biostatistics, Paris (France); Maeder, Philippe [Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne, Department of Radiology, Lausanne (Switzerland); Goericke, Sophia [University Hospital Essen, Institute of Diagnostic and Interventional Radiology and Neuroradiology, Essen (Germany); Aerts, Isabelle [Institut Curie, Department of Pediatric Oncology, Paris (France); Desjardins, Laurence [Institut Curie, Department of Ophthalmology, Paris (France); Moll, Annette C. [VU University Medical Center, Department of Ophthalmology, Amsterdam (Netherlands); Hadjistilianou, Theodora [Azienda Ospedaliera Universitaria Senese, Department of Ophthalmology, Siena (Italy); Toti, Paolo [University of Siena, Department of Medical Biotechnologies, Pathology Unit, Siena (Italy); Valk, Paul van der [VU University Medical Center, Department of Pathology, Amsterdam (Netherlands); Sastre-Garau, Xavier [Institut Curie, Department of Biopathology, Paris (France); Collaboration: European Retinoblastoma Imaging Collaboration (ERIC)

    2015-05-01

    To assess the accuracy of high-resolution (HR) magnetic resonance imaging (MRI) in diagnosing early-stage optic nerve (ON) invasion in a retinoblastoma cohort. This IRB-approved, prospective multicenter study included 95 patients (55 boys, 40 girls; mean age, 29 months). 1.5-T MRI was performed using surface coils before enucleation, including spin-echo unenhanced and contrast-enhanced (CE) T1-weighted sequences (slice thickness, 2 mm; pixel size <0.3 x 0.3 mm{sup 2}). Images were read by five neuroradiologists blinded to histopathologic findings. ROC curves were constructed with AUC assessment using a bootstrap method. Histopathology identified 41 eyes without ON invasion and 25 with prelaminar, 18 with intralaminar and 12 with postlaminar invasion. All but one were postoperatively classified as stage I by the International Retinoblastoma Staging System. The accuracy of CE-T1 sequences in identifying ON invasion was limited (AUC = 0.64; 95 % CI, 0.55 - 0.72) and not confirmed for postlaminar invasion diagnosis (AUC = 0.64; 95 % CI, 0.47 - 0.82); high specificities (range, 0.64 - 1) and negative predictive values (range, 0.81 - 0.97) were confirmed. HR-MRI with surface coils is recommended to appropriately select retinoblastoma patients eligible for primary enucleation without the risk of IRSS stage II but cannot substitute for pathology in differentiating the first degrees of ON invasion. (orig.)

  2. CCHMM_PROF: a HMM-based coiled-coil predictor with evolutionary information

    DEFF Research Database (Denmark)

    Bartoli, Lisa; Fariselli, Piero; Krogh, Anders

    2009-01-01

    tools are available for predicting coiled-coil domains in protein sequences, including those based on position-specific score matrices and machine learning methods. RESULTS: In this article, we introduce a hidden Markov model (CCHMM_PROF) that exploits the information contained in multiple sequence...... alignments (profiles) to predict coiled-coil regions. The new method discriminates coiled-coil sequences with an accuracy of 97% and achieves a true positive rate of 79% with only 1% of false positives. Furthermore, when predicting the location of coiled-coil segments in protein sequences, the method reaches...

  3. Transient voltage oscillations in coils

    International Nuclear Information System (INIS)

    Chowdhuri, P.

    1985-01-01

    Magnet coils may be excited into internal voltage oscillations by transient voltages. Such oscillations may electrically stress the magnet's dielectric components to many times its normal stress. This may precipitate a dielectric failure, and the attendant prolonged loss of service and costly repair work. Therefore, it is important to know the natural frequencies of oscillations of a magnet during the design stage, and to determine whether the expected switching transient voltages can excite the magnet into high-voltage internal oscillations. The series capacitance of a winding significantly affects its natural frequencies. However, the series capacitance is difficult to calculate, because it may comprise complex capacitance network, consisting of intra- and inter-coil turn-to-turn capacitances of the coil sections. A method of calculating the series capacitance of a winding is proposed. This method is rigorous but simple to execute. The time-varying transient voltages along the winding are also calculated

  4. Large coil program support structure conceptual design

    International Nuclear Information System (INIS)

    Litherland, P.S.

    1977-01-01

    The purpose of the Large Coil Program (LCP) is to perform tests on both pool boiling and force cooled superconducting toroidal field coils. The tests will attempt to approximate conditions anticipated in an ignition tokamak. The test requirements resulted in a coil support design which accommodates up to six (6) test coils and is mounted to a structure capable of resisting coil interactions. The steps leading to the present LCP coil support structure design, details on selected structural components, and the basic assembly sequence are discussed

  5. Design Optimization for a Maglev System Employing Flux Eliminating Coils

    Science.gov (United States)

    Davey, Kent R.

    1996-01-01

    Flux eliminating coils have received no little attention over the past thirty years as an alternative for realizing lift in a MAGLEV system. When the magnets on board the vehicle are displaced from the equilibrium or null flux point of these coils, they induce current in those coils which act to restore the coil to its null flux or centerline position. The question being addressed in this paper is that of how to choose the best coil for a given system. What appears at first glance to be an innocent question is in fact one that is actually quite involved, encompassing both the global economics and physics of the system. The real key in analyzing that question is to derive an optimization index or functional which represents the cost of the system subject to constraints, the primary constraint being that the vehicle lift itself at a certain threshold speed. Outlined in this paper is one scenario for realizing a total system design which uses sequential quadratic programming techniques.

  6. Cooling device of superconducting coils

    International Nuclear Information System (INIS)

    Duthil, R.; Lottin, J.C.

    1985-01-01

    This device is rotating around an horizontal axis. The superconducting coils are contained in a cryogenic enclosure feeded in liquid helium forced circulation. They are related to an electric generator by electric mains each of them comprising a gas exchanger, and an exchanger-evaporator set between the cryogenic device and those exchangers. The exchanger-evaporator is aimed at dissipating the heat arriving by conductors connected to the superconducting coils. According to the invention, the invention includes an annular canalization with horizontal axis in which the connection conductors bathe in liquid helium [fr

  7. Characteristic of wireless power transmission S-Parameter for a superconductor coil

    International Nuclear Information System (INIS)

    Jeong, In Sung; Jung, Byung Ik; Choi, Hyo Sang

    2015-01-01

    Many studies are being conducted to implement wireless charging, for example, for cellular phones or electronic tooth brushes, via wireless power transmission technique. However, the magnetic induction method had a very short transmission distance. To solve this problem, the team of Professor Marin Soljacic proposed a magnetic resonance system that used two resonance coils with the same resonance frequency. It had an approximately 40% efficiency at a 2m distance. The system improved the low efficiency and short distance problems of the existing systems. So it could also widen the application range of wireless power transmission. Many studies on the subject are underway. In this paper, the superconductor coil was used to improve the efficiency of magnetic resonance wireless power transmission. The resonance wireless power transmission system had a source coil, a load coil, and resonance coils (a transmitter and a receiver). The efficiency and distance depended on the characteristics of the transmitter and receiver coils that had the same resonance frequency. Therefore, two resonance coils were fabricated by superconductors. The current density of the superconductor was higher than that of the normal conductor coil. Accordingly, it had a high quality-factor and improved efficiency

  8. Characteristic of wireless power transmission S-Parameter for a superconductor coil

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, In Sung; Jung, Byung Ik; Choi, Hyo Sang [Chosun University, Gwangju (Korea, Republic of)

    2015-03-15

    Many studies are being conducted to implement wireless charging, for example, for cellular phones or electronic tooth brushes, via wireless power transmission technique. However, the magnetic induction method had a very short transmission distance. To solve this problem, the team of Professor Marin Soljacic proposed a magnetic resonance system that used two resonance coils with the same resonance frequency. It had an approximately 40% efficiency at a 2m distance. The system improved the low efficiency and short distance problems of the existing systems. So it could also widen the application range of wireless power transmission. Many studies on the subject are underway. In this paper, the superconductor coil was used to improve the efficiency of magnetic resonance wireless power transmission. The resonance wireless power transmission system had a source coil, a load coil, and resonance coils (a transmitter and a receiver). The efficiency and distance depended on the characteristics of the transmitter and receiver coils that had the same resonance frequency. Therefore, two resonance coils were fabricated by superconductors. The current density of the superconductor was higher than that of the normal conductor coil. Accordingly, it had a high quality-factor and improved efficiency.

  9. Large Coil Program magnetic system design study

    International Nuclear Information System (INIS)

    Moses, S.D.; Johnson, N.E.

    1977-01-01

    The primary objective of the Large Coil Program (LCP) is to demonstrate the reliable operation of large superconducting coils to provide a basis for the design principles, materials, and fabrication techniques proposed for the toroidal magnets for the THE NEXT STEP (TNS) and other future tokamak devices. This paper documents a design study of the Large Coil Test Facility (LCTF) in which the structural response of the Toroidal Field (TF) Coils and the supporting structure was evaluated under simulated reactor conditions. The LCP test facility structural system consists of six TF Coils, twelve coil-to-coil torsional restraining beams (torque rings), a central bucking post with base, and a Pulse Coil system. The NASTRAN Finite Element Structural Analysis computer Code was utilized to determine the distribution of deflections, forces, and stresses for each of the TF Coils, torque rings, and the central bucking post. Eleven load conditions were selected to represent probable test operations. Pulse Coils suspended in the bore of the test coil were energized to simulate the pulsed field environment characteristic of the TNS reactor system. The TORMAC Computer Code was utilized to develop the magnetic forces in the TF Coils for each of the eleven loading conditions examined, with or without the Pulse Coils energized. The TORMAC computer program output forces were used directly as input load conditions for the NASTRAN analyses. Results are presented which demonstrate the reliability of the LCTF under simulated reactor operating conditions

  10. Finite element coiled cochlea model

    Science.gov (United States)

    Isailovic, Velibor; Nikolic, Milica; Milosevic, Zarko; Saveljic, Igor; Nikolic, Dalibor; Radovic, Milos; Filipović, Nenad

    2015-12-01

    Cochlea is important part of the hearing system, and thanks to special structure converts external sound waves into neural impulses which go to the brain. Shape of the cochlea is like snail, so geometry of the cochlea model is complex. The simplified cochlea coiled model was developed using finite element method inside SIFEM FP7 project. Software application is created on the way that user can prescribe set of the parameters for spiral cochlea, as well as material properties and boundary conditions to the model. Several mathematical models were tested. The acoustic wave equation for describing fluid in the cochlea chambers - scala vestibuli and scala timpani, and Newtonian dynamics for describing vibrations of the basilar membrane are used. The mechanical behavior of the coiled cochlea was analyzed and the third chamber, scala media, was not modeled because it does not have a significant impact on the mechanical vibrations of the basilar membrane. The obtained results are in good agreement with experimental measurements. Future work is needed for more realistic geometry model. Coiled model of the cochlea was created and results are compared with initial simplified coiled model of the cochlea.

  11. BPX toroidal field coil design

    International Nuclear Information System (INIS)

    Heitzenvoeder, D.J.

    1992-01-01

    This paper reports on the toroidal field (TF) coil system of the Burning Plasma Experiment (BPX) which consists of (18) beryllium copper magnets arrayed in a wedged configuration with a major radius of 2.6 meters and a field strength capability on axis of 9.0 Tesla. The toroidal array is constructed from six (3)-coil modules to facilitate remote recovery in the event of a magnet failure after nuclear activation precludes hands-on servicing. The magnets are of a modified Bitter plate design with partial cases of type 316-LN stainless steel welded with Inconel 182 weld wire. The coil turn plates are fabricated from CDA C17510 beryllium copper with optimized mechanical, thermal, and electrical characteristics. joints within the turns and between turns are made by welding with C17200 filler wire. Cryogenic cooling is employed to reduce power dissipation and to enhance performance. The magnets are cooled between experimental pulses by pressurized liquid nitrogen flowing through channels in the edges of the coil turns. This arrangement makes possible one full-power pulse per hour. Electrical insulation consists of polyimide-glass sheets bonded in place with vacuum-pressure impregnated epoxy/glass

  12. Demonstration poloidal coil test facility

    International Nuclear Information System (INIS)

    Sato, Masahiko; Kawano, Katumi; Tada, Eisuke

    1989-01-01

    A new compact cryogenic cold compressor was developed by Japan Atomic Energy Research Institute (JAERI) in collaboration with Isikawajima-Harima Heavy Industries Co., Ltd. (IHI) in order to produce the supercritical helium below 4.2 K for Demonstration Poloidal Coils (DPC) which are forced-flow cooled type superconducting pulse coils. This compressor is one of key components for DPC test facility. The cold compressor reduces pressure in liquid helium bath, which contains liquid helium of around 3,000 l, down to 0.5 atm efficiently. Consequently, supercritical helium down to 3.5 K is produced and supplied to the DPC coils. A centrifugal compressor with dynamic gas bearing is selected as a compressor mechanism to realize high adiabatic efficiency and large flow rate. In this performance tests, the compressor was operated for 220 h at saturated condition from 0.5 to 1.0 atm without any failure. High adiabatic efficiency (more than 60 %) is achieved with wide flow range (25-65 g/s) and the design value is fully satisfied. The compressor can rotate up to 80,000 rpm at maximum then the coil supply temperature of supercritical helium is 3.5 K. (author)

  13. Open-Coil Retraction Spring

    Directory of Open Access Journals (Sweden)

    Pavankumar Janardan Vibhute

    2011-01-01

    Full Text Available Sliding mechanic has become a popular method for space closure with developments in preadjusted edgewise appliance. Furthermore, various space closing auxiliaries have been developed and evaluated extensively for their clinical efficiency. Their effectiveness enhanced with optimum force magnitude and low-load deflection rate (LDR/force decay. With the advent of NiTi springs in orthodontics, LDRs have been markedly reduced. For use of NiTi, clinician has to depend upon prefabricated closed coil springs. “Open Coil Retraction Spring (OCRS” is developed utilizing NiTi open-coil spring for orthodontic space closure. This paper describes fabrication and clinical application of OCRS which have number of advantages. It sustains low LDR with optimum force magnitude. Its design is adjustable for desired length and force level. It is fail-safe for both activation and deactivation (i.e., it cannot be over activated, and decompression limit of open coil is also controlled by the operator, resp.. A possibility to offset the OCRS away from mucosa helps to reduce its soft-tissue impingement.

  14. PDX toroidal field coils stress analysis

    International Nuclear Information System (INIS)

    Nikodem, Z.D.; Smith, R.A.

    1975-01-01

    A method used in the stress analysis of the PDX toroidal field coil is developed. A multilayer coil design of arbitrary dimensions in the shape of either a circle or an oval is considered. The analytical model of the coil and the supporting coil case with connections to the main support structure is analyzed using the finite element technique. The three dimensional magnetic fields and the non-uniform body forces which are a loading condition on a coil due to toroidal and poloidal fields are calculated. The method of analysis permits rapid and economic evaluations of design changes in coil geometry as well as in coil support structures. Some results pertinent to the design evolution and their comparison are discussed. The results of the detailed stress analysis of the final coil design due to toroidal field, poloidal field and temperature loads are presented

  15. Bow-shaped toroidal field coils

    International Nuclear Information System (INIS)

    Bonanos, P.

    1981-05-01

    Design features of Bow-Shaped Toroidal Field Coils are described and compared with circular and D shaped coils. The results indicate that bow coils can produce higher field strengths, store more energy and be made demountable. The design offers the potential for the production of ultrahigh toroidal fields. Included are representative coil shapes and their engineering properties, a suggested structural design and an analysis of a specific case

  16. Design and modelling of a SMES coil

    Energy Technology Data Exchange (ETDEWEB)

    Yuan Weijia; Campbell, A M; Coombs, T A, E-mail: wy215@cam.ac.u [EPEC Superconductivity group, Engineering Department, 9 JJ Thomson Avenue, Cambridge, CB3 0FA (United Kingdom)

    2010-06-01

    The design of a Superconducting Magnetic Energy Storage (SMES) coil wound by coated conductors has been presented. Based on an existing model for coated conductor pancake coils, this paper analysed the magnetic field and current density distribution of the coil at two different operation temperatures, 77K and 22K. A comparison table of the critical currents and AC losses at these two temperatures has been presented. Several steps to improve the transport current of the coil have been suggested as well.

  17. MRI performed on dedicated knee coils is inaccurate for the measurement of tibial tubercle trochlear groove distance

    International Nuclear Information System (INIS)

    Aarvold, A.; Pope, A.; Sakthivel, V.K.; Ayer, R.V.

    2014-01-01

    Tibial tubercle trochlear groove distance (TTD) is a significant factor in patello-femoral instability. Initially described on CT scans with the knee in full extension, the measurement has been validated on MR scans. Dedicated knee MRI coils have subsequently superseded both CT and MRI body coils for knee imaging. However, the knee rests in partial flexion within the dedicated knee coil. The objective of this study is to investigate whether images from dedicated knee MRI coils produce different TTD measurements from MR body coils. Thirty-two symptomatic knees (27 patients) had simultaneous knee MR scans performed in both a dedicated knee coil and a body coil. TTD measurements were independently compared to assess whether the coil type used affected TTD. Patients' ages ranged from 10 to 27 years (mean 15 years). Mean TTD in the dedicated knee coil (partially flexed knee) was 11.3 mm compared with 19.9 mm in the body coil (that permits full knee extension). The mean difference was 8.6 mm, which was highly significant (p < 0.0001, unpaired t test). Inter-rater correlation co-efficient was 96 %. Of the knees that recorded a ''normal'' TTD on the dedicated knee coil, 60-100 % recorded a ''pathological'' TTD on body coil images, depending on which diagnostic value for ''normal'' cut-off was used. This study has identified a highly significant difference in TTD measurement when knees are scanned in a dedicated knee coil with the knee partially flexed, compared with an MR body coil. It is critical for surgeons and radiologists managing patello-femoral instability to appreciate this profound difference. TTD measurement taken from knees scanned in dedicated knee coils may lead to patients being falsely re-assured or erroneously denied surgery. (orig.)

  18. Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif

    DEFF Research Database (Denmark)

    Céspedes, Nora; Habel, Catherine; Lopez-Perez, Mary

    2014-01-01

    Protein α-helical coiled coil structures that elicit antibody responses, which block critical functions of medically important microorganisms, represent a means for vaccine development. By using bioinformatics algorithms, a total of 50 antigens with α-helical coiled coil motifs orthologous to Pla...

  19. Sensitive quench detection of the HTS coil using a co-winding coil

    International Nuclear Information System (INIS)

    Takagi, Tomohiro; Ariyama, Takahiro; Takao, Tomoaki; Tsukamoto, Osami

    2017-01-01

    The authors have studied the co-winding coil method (CW method) using the co-wound coil electrically insulated from the HTS coil. In this method, the quench is detected by the voltage difference between the coil of the HTS tape (HTS coil) and the coil of the normal conductor (CW coil). The voltage induced in the CW coil caused by the change of the magnetic field is almost the same as that in the HTS coil because the coils are magnetically coupled close to each other. Therefore, it is expected that the induced voltage will be canceled with high accuracy and that the resistive voltage in the HTS coil will be detected with greater sensitivity compared to the bridge balance method, which is used commonly. In this study, quench detection applying the CW method is demonstrated using an experimental double-pancake coil. A tape with the copper layer deposited on the polymer substrate was used as the insulated conductor wire to form the CW coil. An additional pancake coil was used to expose the experimental double-pancake coil to the external magnetic field asymmetrically. It was shown that the CW method can detect the resistive voltage with greater sensitivity even when the HTS coil was exposed to the changing asymmetric external magnetic field. (author)

  20. Status of the Swiss LCT-coil

    International Nuclear Information System (INIS)

    Zichy, J; Benz, H.; Horvath, I.; Jakob, B.; Marinucci, C.; Vecsey, G.; Weymuth, P.; Zellweger, J.

    1983-01-01

    The Swiss coil is a forced flow coil cooled by supercritical helium. A brief review of the design considerations, some of its specific features, and the progress in fabrication are described. A discussion of both the instrumentation and the cryogenic characteristics of the coil is presented

  1. Linear motor coil assembly and linear motor

    NARCIS (Netherlands)

    2009-01-01

    An ironless linear motor (5) comprising a magnet track (53) and a coil assembly (50) operating in cooperation with said magnet track (53) and having a plurality of concentrated multi-turn coils (31 a-f, 41 a-d, 51 a-k), wherein the end windings (31E) of the coils (31 a-f, 41 a-e) are substantially

  2. Split Coil Forms for Rotary Transformers

    Science.gov (United States)

    Mclyman, C. W. T.

    1982-01-01

    Split cores for rotor and stator windings of rotary transformer mounted around their respective coils (which are in bobbins) and cemented together. This arrangement simplifies winding of stator coil to go in a slot in inner diameter of stator coil. One practical application of rotary transformers fabricated according to this technique is for centrifuges, in which conventional sliprings are of uncertain reliability.

  3. Startup of large coil test facility

    International Nuclear Information System (INIS)

    Haubenreich, P.N.; Bohanan, R.E.; Fietz, W.A.; Luton, J.N.; May, J.R.

    1984-01-01

    The Large Coil Test Facility (LCTF) is being used to test superconducting toroidal field coils about one-third the size of those for INTOR. Data were obtained on performance of refrigerator, helium distribution, power supplies, controls, and data acquisition systems and on the acoustic emission, voltages, currents, and mechanical strains during charging and discharging the coils. (author)

  4. Novel method of aligning ATF-1 coils

    International Nuclear Information System (INIS)

    Rome, J.A.; Harris, J.H.; Neilson, G.H.; Jernigan, T.C.

    1983-08-01

    The coils for the Advanced Toroidal Facility (ATF-1) torsatron may be easily aligned before the machine is placed under vacuum. This is done by creating nulls in the magnetic field by energizing the coils in various configurations. All of the nulls in vertical bar B vector vertical bar occur on the z-axis. When the nulls coincide, the coils are properly aligned

  5. Self-Assembly of Rod-Coil Block Copolymers

    National Research Council Canada - National Science Library

    Jenekhe, S

    1999-01-01

    ... the self-assembly of new rod-coil diblock, rod- coil-rod triblock, and coil-rod-coil triblock copolymers from solution and the resulting discrete and periodic mesostmctares with sizes in the 100...

  6. Design of a coil sensor for time domain electromagnetic system for uranium exploration

    International Nuclear Information System (INIS)

    Keshwani, R.T.; Bhattacharya, S.

    2011-01-01

    Time domain electromagnetic system is used for exploration of deep seated deposits under the Earth surface. The basic principle is to set up eddy currents in conductors using pulsed excited transmitter coil during on time of a pulse. The decay time of eddy currents during off time of a pulse is a function conductivity, permeability and depth of conductor located under the Earth surface. The technology is being developed to carry out exploration of mineral deposits (basically uranium) under the Earth surface. The decay of eddy currents is eddy using J coil sensor located coplanar with the transmitter coil. The depth upto which successful exploration can be carried is strong function of design of receiver coil. The design parameters include number of turns, bandwidth, stray capacitance and resistance of a coil. This paper describes various designs tried out and their characterization results. Field results for a ground based system developed are also described. (author)

  7. Design of an interventional magnetic resonance imaging coil for cerebral surgery

    Science.gov (United States)

    Xu, Yue; Wang, Wen-Tao; Wang, Wei-Min

    2012-11-01

    In clinical magnetic resonance imaging (MRI), the design of the radiofrequency (RF) coil is very important. For certain applications, the appropriate coil can produce an improved image quality. However, it is difficult to achieve a uniform B1 field and a high signal-to-noise ratio (SNR) simultaneously. In this article, we design an interventional transmitter-and-receiver RF coil for cerebral surgery. This coil adopts a disassembly structure that can be assembled and disassembled repeatedly on the cerebral surgery gantry to reduce the amount of interference from the MRI during surgery. The simulation results and the imaging experiments demonstrate that this coil can produce a uniform RF field, a high SNR, and a large imaging range to meet the requirements of the cerebral surgery.

  8. Diversity receiver

    NARCIS (Netherlands)

    2005-01-01

    The invention is directed to the reception of high rate radio signals (for example DVB-T signals) while the receiver is moving at a high speed (for example in or with a car). Two or more antennas (12, 16) are closely spaced and arranged behind each other in the direction of motion (v) for receiving

  9. Coil Migration through a Neuroform 3 Stent during Endovascular Coiling. A Case Report.

    LENUS (Irish Health Repository)

    O'Hare, A

    2009-07-29

    Summary: A 43-year-old woman attended for stent assisted coiling. A Neuroform 30 x 4.5 mm stent had been successfully placed over the left periophthalmic aneurysm. During the coiling the first coil migrated through the crowns in the stent, lodging at the MCA bifurcation. We believe that the coil herniated through the overlying stent due to the carotid siphon curvature and the open cell design. Furthermore the distal markers of the stent impeded coil extraction with a MERCI device.

  10. An inflatable surface coil for rectal imaging

    International Nuclear Information System (INIS)

    Martin, J.F.; Hajek, P.C.; Baker, L.L.; Gylys-Morin, V.; Mattrey, R.F.

    1986-01-01

    Surface coils have become ubiquitous in MR imaging of the body because of substantial gains in signal-to-noise ratio. Unfortunately, there are some anatomic regions, such as the prostate, for which surface coils have insufficient depth sensitivity. The authors have developed an inflatable, distributed capacitance, passively decoupled surface coil which is collapsed for insertion and reinflated for imaging. Images of the prostate are dramatically improved due to proximity of the coil. Lesions in cadaver specimens were observed which were not seen with body coil imaging. Clinical trials are expected to begin in September

  11. A combined solenoid-surface RF coil for high-resolution whole-brain rat imaging on a 3.0 Tesla clinical MR scanner.

    Science.gov (United States)

    Underhill, Hunter R; Yuan, Chun; Hayes, Cecil E

    2010-09-01

    Rat brain models effectively simulate a multitude of human neurological disorders. Improvements in coil design have facilitated the wider utilization of rat brain models by enabling the utilization of clinical MR scanners for image acquisition. In this study, a novel coil design, subsequently referred to as the rat brain coil, is described that exploits and combines the strengths of both solenoids and surface coils into a simple, multichannel, receive-only coil dedicated to whole-brain rat imaging on a 3.0 T clinical MR scanner. Compared with a multiturn solenoid mouse body coil, a 3-cm surface coil, a modified Helmholtz coil, and a phased-array surface coil, the rat brain coil improved signal-to-noise ratio by approximately 72, 61, 78, and 242%, respectively. Effects of the rat brain coil on amplitudes of static field and radiofrequency field uniformity were similar to each of the other coils. In vivo, whole-brain images of an adult male rat were acquired with a T(2)-weighted spin-echo sequence using an isotropic acquisition resolution of 0.25 x 0.25 x 0.25 mm(3) in 60.6 min. Multiplanar images of the in vivo rat brain with identification of anatomic structures are presented. Improvement in signal-to-noise ratio afforded by the rat brain coil may broaden experiments that utilize clinical MR scanners for in vivo image acquisition. 2010 Wiley-Liss, Inc.

  12. ANL experimental program for pulsed superconducting coils

    International Nuclear Information System (INIS)

    Wang, S.T.; Kim, S.H.; Praeg, W.F.; Krieger, C.I.

    1978-01-01

    Argonne National Laboratory (ANL) had recognized the clear advantage of a superconducting ohmic-heating (OH) coil and started in aggressive development program in FY 1977. The main objectives for FY 1977 are to develop cryostable basic cable configurations with reasonably low ac losses, to develop 12 kA cryostable cable, using it to design and build a 1.5 MJ pulsed coil, and to develop a rather inexpensive large fiberglass reinforced helium cryostat for the 1.5 MJ pulsed coil. The principal objective in building the 1.5 MJ ac coil is to demonstrate ac cryostability of a large coil ranging from 2 T/s up to 12 T/s. Another objective in the pulsed coil program is to determine the feasibility of parallel coil operation in order to avoid excessive voltage and current requirements and to minimize the number of turns for the equilibrium field (EF) coils, should the EF coils be connected in parallel with the OH coils. A two-coil section model using the 11 kA cable will be built and tested

  13. Pulse coil concepts for the LCP Facility

    International Nuclear Information System (INIS)

    Nelson, B.E.; Burn, P.B.

    1977-01-01

    The pulse coils described in this paper are resistive copper magnets driven by time-varying currents. They are included in the Large Coil Test Facility (LCTF) portion of the Large Coil Program (LCP) to simulate the pulsed field environment of the toroidal coils in a tokamak reactor. Since TNS (a 150 sec, 5MA, igniting tokamak) and the Oak Ridge EPR (Experimental Power Reactor) are representative of the first tokamaks to require the technology developed in LCP, the reference designs for these machines, especially TNS, are used to derive the magnetic criteria for the pulse coils. This criteria includes the magnitude, distribution, and rate of change of pulsed fields in the toroidal coil windings. Three pulse coil concepts are evaluated on the basis of magnetic criteria and factors such as versatility of design, ease of fabrication and cost of operation. The three concepts include (1) a pair of poloidal coils outside the LCTF torus, (2) a single poloidal coil threaded through the torus, and (3) a pair of vertical axis coil windings inside the bore of one or more of the toroidal test coils

  14. ANL experimental program for pulsed superconducting coils

    International Nuclear Information System (INIS)

    Wang, S.T.; Kim, S.H.; Praeg, W.F.; Krieger, C.I.

    1977-01-01

    Argonne National Laboratory (ANL) had recognized the clear advantage of a superconducting ohmic-heating (OH) coil and started an aggressive development program in FY 1977. The main objectives for FY 1977 are to develop cryostable basic cable configurations with reasonably low ac losses, to develop 12 kA cryostable cable, using it to design and build a 1.5 MJ pulsed coil, and to develop a rather inexpensive large fiberglass reinforced helium cryostat for the 1.5 MJ pulsed coil. The principal objective in building the 1.5 MJ ac coil is to demonstrate ac cryostability of a large coil ranging from 2 T/s up to 12 T/s. Another objective in the pusled coil program is to determine the feasibility of parallel coil operation in order to avoid excessive voltage and current requirements and to minimize the number of turns for the equilibrium field (EF) coils, should the EF coils be connected in parallel with the OH coils. A two-coil section model using the 11 kA cable will be built and tested

  15. Performance evaluation of matrix gradient coils.

    Science.gov (United States)

    Jia, Feng; Schultz, Gerrit; Testud, Frederik; Welz, Anna Masako; Weber, Hans; Littin, Sebastian; Yu, Huijun; Hennig, Jürgen; Zaitsev, Maxim

    2016-02-01

    In this paper, we present a new performance measure of a matrix coil (also known as multi-coil) from the perspective of efficient, local, non-linear encoding without explicitly considering target encoding fields. An optimization problem based on a joint optimization for the non-linear encoding fields is formulated. Based on the derived objective function, a figure of merit of a matrix coil is defined, which is a generalization of a previously known resistive figure of merit for traditional gradient coils. A cylindrical matrix coil design with a high number of elements is used to illustrate the proposed performance measure. The results are analyzed to reveal novel features of matrix coil designs, which allowed us to optimize coil parameters, such as number of coil elements. A comparison to a scaled, existing multi-coil is also provided to demonstrate the use of the proposed performance parameter. The assessment of a matrix gradient coil profits from using a single performance parameter that takes the local encoding performance of the coil into account in relation to the dissipated power.

  16. Single-Coil Defibrillator Leads Yield Satisfactory Defibrillation Safety Margin in Hypertrophic Cardiomyopathy.

    Science.gov (United States)

    Okamura, Hideo; Friedman, Paul A; Inoue, Yuko; Noda, Takashi; Aiba, Takeshi; Yasuda, Satoshi; Ogawa, Hisao; Kamakura, Shiro; Kusano, Kengo; Espinosa, Raul E

    2016-09-23

    Single-coil defibrillator leads have gained favor because of their potential ease of extraction. However, a high defibrillation threshold remains a concern in patients with hypertrophic cardiomyopathy (HCM), and in many cases, dual-coil leads have been used for this patient group. There is little data on using single-coil leads for HCM patients. We evaluated 20 patients with HCM who received an implantable cardioverter-defibrillator (ICD) on the left side in combination with a dual-coil lead. Two sets of defibrillation tests were performed in each patient, one with the superior vena cava (SVC) coil "on" and one with the SVC coil "off". ICDs were programmed to deliver 25 joules (J) for the first attempt followed by maximum energy (35 J or 40 J). Shock impedance and shock pulse width at 25 J in each setting as well as the results of the shock were analyzed. All 25-J shocks in both settings successfully terminated ventricular fibrillation. However, shock impedance and pulse width increased substantially with the SVC coil programmed "off" compared with "on" (66.4±6.1 ohm and 14.0±1.3 ms "off" vs. 41.9±5.0 ohm and 9.3±0.8 ms "on", Psatisfactory safety margin for 35-J devices. Single-coil leads appear appropriate for left-sided implantation in this patient group. (Circ J 2016; 80: 2199-2203).

  17. High performance 3-coil wireless power transfer system for the 512-electrode epiretinal prosthesis.

    Science.gov (United States)

    Zhao, Yu; Nandra, Mandheerej; Yu, Chia-Chen; Tai, Yu-chong

    2012-01-01

    The next-generation retinal prostheses feature high image resolution and chronic implantation. These features demand the delivery of power as high as 100 mW to be wireless and efficient. A common solution is the 2-coil inductive power link, used by current retinal prostheses. This power link tends to include a larger-size extraocular receiver coil coupled to the external transmitter coil, and the receiver coil is connected to the intraocular electrodes through a trans-sclera trans-choroid cable. In the long-term implantation of the device, the cable may cause hypotony (low intraocular pressure) and infection. However, when a 2-coil system is constructed from a small-size intraocular receiver coil, the efficiency drops drastically which may induce over heat dissipation and electromagnetic field exposure. Our previous 2-coil system achieved only 7% power transfer. This paper presents a fully intraocular and highly efficient wireless power transfer system, by introducing another inductive coupling link to bypass the trans-sclera trans-choroid cable. With the specific equivalent load of our customized 512-electrode stimulator, the current 3-coil inductive link was measured to have the overall power transfer efficiency around 36%, with 1-inch separation in saline. The high efficiency will favorably reduce the heat dissipation and electromagnetic field exposure to surrounding human tissues. The effect of the eyeball rotation on the power transfer efficiency was investigated as well. The efficiency can still maintain 14.7% with left and right deflection of 30 degree during normal use. The surgical procedure for the coils' implantation into the porcine eye was also demonstrated.

  18. Coiled transmission line pulse generators

    Science.gov (United States)

    McDonald, Kenneth Fox

    2010-11-09

    Methods and apparatus are provided for fabricating and constructing solid dielectric "Coiled Transmission Line" pulse generators in radial or axial coiled geometries. The pour and cure fabrication process enables a wide variety of geometries and form factors. The volume between the conductors is filled with liquid blends of monomers, polymers, oligomers, and/or cross-linkers and dielectric powders; and then cured to form high field strength and high dielectric constant solid dielectric transmission lines that intrinsically produce ideal rectangular high voltage pulses when charged and switched into matched impedance loads. Voltage levels may be increased by Marx and/or Blumlein principles incorporating spark gap or, preferentially, solid state switches (such as optically triggered thyristors) which produce reliable, high repetition rate operation. Moreover, these Marxed pulse generators can be DC charged and do not require additional pulse forming circuitry, pulse forming lines, transformers, or an a high voltage spark gap output switch. The apparatus accommodates a wide range of voltages, impedances, pulse durations, pulse repetition rates, and duty cycles. The resulting mobile or flight platform friendly cylindrical geometric configuration is much more compact, light-weight, and robust than conventional linear geometries, or pulse generators constructed from conventional components. Installing additional circuitry may accommodate optional pulse shape improvements. The Coiled Transmission Lines can also be connected in parallel to decrease the impedance, or in series to increase the pulse length.

  19. Conformational switching in the coiled-coil domains of a proteasomal ATPase regulates substrate processing.

    Science.gov (United States)

    Snoberger, Aaron; Brettrager, Evan J; Smith, David M

    2018-06-18

    Protein degradation in all domains of life requires ATPases that unfold and inject proteins into compartmentalized proteolytic chambers. Proteasomal ATPases in eukaryotes and archaea contain poorly understood N-terminally conserved coiled-coil domains. In this study, we engineer disulfide crosslinks in the coiled-coils of the archaeal proteasomal ATPase (PAN) and report that its three identical coiled-coil domains can adopt three different conformations: (1) in-register and zipped, (2) in-register and partially unzipped, and (3) out-of-register. This conformational heterogeneity conflicts with PAN's symmetrical OB-coiled-coil crystal structure but resembles the conformational heterogeneity of the 26S proteasomal ATPases' coiled-coils. Furthermore, we find that one coiled-coil can be conformationally constrained even while unfolding substrates, and conformational changes in two of the coiled-coils regulate PAN switching between resting and active states. This switching functionally mimics similar states proposed for the 26S proteasome from cryo-EM. These findings thus build a mechanistic framework to understand regulation of proteasome activity.

  20. Computational fluid dynamics (CFD) using porous media modeling predicts recurrence after coiling of cerebral aneurysms.

    Science.gov (United States)

    Umeda, Yasuyuki; Ishida, Fujimaro; Tsuji, Masanori; Furukawa, Kazuhiro; Shiba, Masato; Yasuda, Ryuta; Toma, Naoki; Sakaida, Hiroshi; Suzuki, Hidenori

    2017-01-01

    This study aimed to predict recurrence after coil embolization of unruptured cerebral aneurysms with computational fluid dynamics (CFD) using porous media modeling (porous media CFD). A total of 37 unruptured cerebral aneurysms treated with coiling were analyzed using follow-up angiograms, simulated CFD prior to coiling (control CFD), and porous media CFD. Coiled aneurysms were classified into stable or recurrence groups according to follow-up angiogram findings. Morphological parameters, coil packing density, and hemodynamic variables were evaluated for their correlations with aneurysmal recurrence. We also calculated residual flow volumes (RFVs), a novel hemodynamic parameter used to quantify the residual aneurysm volume after simulated coiling, which has a mean fluid domain > 1.0 cm/s. Follow-up angiograms showed 24 aneurysms in the stable group and 13 in the recurrence group. Mann-Whitney U test demonstrated that maximum size, dome volume, neck width, neck area, and coil packing density were significantly different between the two groups (P CFD and larger RFVs in the porous media CFD. Multivariate logistic regression analyses demonstrated that RFV was the only independently significant factor (odds ratio, 1.06; 95% confidence interval, 1.01-1.11; P = 0.016). The study findings suggest that RFV collected under porous media modeling predicts the recurrence of coiled aneurysms.

  1. Detection of Galactomannan Antigenemia in Patients Receiving Piperacillin-Tazobactam and Correlations between In Vitro, In Vivo, and Clinical Properties of the Drug-Antigen Interaction

    Science.gov (United States)

    Walsh, Thomas J.; Shoham, Shmuel; Petraitiene, Ruta; Sein, Tin; Schaufele, Robert; Kelaher, Amy; Murray, Heidi; Mya-San, Christine; Bacher, John; Petraitis, Vidmantas

    2004-01-01

    Recent case reports describe patients receiving piperacillin-tazobactam who were found to have circulating galactomannan detected by the double sandwich enzyme-linked immunosorbent assay (ELISA) system, leading to the false presumption of invasive aspergillosis. Since this property of piperacillin-tazobactam and galactomannan ELISA is not well understood, we investigated the in vitro, in vivo, and clinical properties of this interaction. Among the 12 reconstituted antibiotics representing four classes of antibacterial compounds that are commonly used in immunocompromised patients, piperacillin-tazobactam expressed a distinctively high level of galactomannan antigen in vitro (P = 0.001). After intravenous infusion of piperacillin-tazobactam into rabbits, the serum galactomannan index (GMI) in vivo changed significantly (P = 0.0007) from a preinfusion mean baseline value of 0.27 to a mean GMI of 0.83 by 30 min to slowly decline to a mean GMI of 0.44 24 h later. Repeated administration of piperacillin-tazobactam over 7 days resulted in accumulation of circulating galactomannan to a mean peak GMI of 1.31 and a nadir of 0.53. Further studies revealed that the antigen reached a steady state by the third day of administration of piperacillin-tazobactam. Twenty-six hospitalized patients with no evidence of invasive aspergillosis who were receiving antibiotics and ten healthy blood bank donors were studied for expression of circulating galactomannan. Patients (n = 13) receiving piperacillin-tazobactam had significantly greater mean serum GMI values (0.74 ± 0.14) compared to patients (n = 13) receiving other antibiotics (0.14 ± 0.08) and compared to healthy blood bank donors (0.14 ± 0.06) (P 0.5 compared to none of thirteen subjects receiving other antibiotics (P = 0.039) and to none of ten healthy blood bank donors (P = 0.046). These data demonstrate that among antibiotics that are commonly used in immunocompromised patients, only piperacillin-tazobactam contains

  2. Remote maintenance of tandem mirror hybrid coils

    International Nuclear Information System (INIS)

    Dietz, L.P.

    1983-01-01

    Hybrid Coils (superconducting coils with normal conducting inserts) are being employed with increasing frequency on Tandem Mirror Devices to obtain high field strengths. The normal conducting copper inserts are short lived in comparison to their encircling superconductors. It becomes desirable, therefore, to devise design features and maintenance procedures to replace the inner normal conducting coils without simultaneously replacing the longer lived (and significantly more costly) superconducting coils. The high neutron wall loadings require that the task be accomplished by remote control. The approach is to permanently mount the coil assemblies on track mounted carriages which serve, during machine operation merely as structural supports, but during maintenance procedures as moveable transport devices. The carriages incorporate all necessary provisions to facilitate remote maintenance operations and to adjust and align the coil assemblies with respect to adjacent machine components. The vacuum vessel is severed on both sides of the hybrid coil by means of a remote cutting machine. The entire coil is transported horizontally, normal to the machine axis to a nearby repair station. Prepositioned carriage mounted repair equipment at the repair station withdraws the damaged normal coil as a single entity and inserts a preassembled spare unit. The repaired hybrid coil is reassembled to the reactor. A cost and risk effective procedure has been evolved to maintain one of the more critical components of a Tandem Mirror Machine

  3. Discussion of discrete D shape toroidal coil

    International Nuclear Information System (INIS)

    Kaiho, Katsuyuki; Ohara, Takeshi; Agatsuma, Ko; Onishi, Toshitada

    1988-01-01

    A novel design for a toroidal coil, called the D shape coil, was reported by J. File. The coil conductors are in pure tension and then subject to no bending moment. This leads to a smaller number of emf supports in a simpler configuration than that with the conventional toroidal coil of circular cross-section. The contours of the D shape are given as solutions of a differential equation. This equation includes the function of the magnetic field distribution in the conductor region which is inversely proportional to the winding radius. It is therefore important to use the exact magnetic field distribution. However the magnetic field distribution becomes complicated when the D shape toroidal coil is comprised of discrete coils and also depends on the D shape configuration. A theory and a computer program for designing the practical pure-tension toroidal coil are developed. Using this computer code, D shape conductors are calculated for various numbers of discrete coils and the results are compared. Electromagnetic forces in the coils are also calculated. It is shown that the hoop stress in the conductors depends only on the total ampere-turns of the coil when the contours of the D shape are similar. (author)

  4. Large coil test facility conceptual design report

    International Nuclear Information System (INIS)

    Nelms, L.W.; Thompson, P.B.; Mann, T.L.

    1978-02-01

    In the development of a superconducting toroidal field (TF) magnet for The Next Step (TNS) tokamak reactor, several different TF coils, about half TNS size, will be built and tested to permit selection of a design and fabrication procedure for full-scale TNS coils. A conceptual design has been completed for a facility to test D-shaped TF coils, 2.5 x 3.5-m bore, operating at 4-6 K, cooled either by boiling helium or by forced-flow supercritical helium. Up to six coils can be accommodated in a toroidal array housed in a single vacuum tank. The principal components and systems in the facility are an 11-m vacuum tank, a test stand providing structural support and service connections for the coils, a liquid nitrogen system, a system providing helium both as saturated liquid and at supercritical pressure, coils to produce a pulsed vertical field at any selected test coil position, coil power supplies, process instrumentation and control, coil diagnostics, and a data acquisition and handling system. The test stand structure is composed of a central bucking post, a base structure, and two horizontal torque rings. The coils are bolted to the bucking post, which transmits all gravity loads to the base structure. The torque ring structure, consisting of beams between adjacent coils, acts with the bucking structure to react all the magnetic loads that occur when the coils are energized. Liquid helium is used to cool the test stand structure to 5 K to minimize heat conduction to the coils. Liquid nitrogen is used to precool gaseous helium during system cooldown and to provide thermal radiation shielding

  5. Heat loss investigation from spherical cavity receiver of solar concentrator

    Energy Technology Data Exchange (ETDEWEB)

    Shewale, V. C. [Dept. of Mechanical Engineering, NDMVPS KBT College of Engineering, Nashik (India); Dongarwar, P. R. [Dept. of Mechanical Engineering, College of Military Engineering, Pune (India); Gawande, R. P. [Dept. of Mechanical Engineering, B.D.C.O.E. Wardha, Nagpur University, NagpurI (India)

    2016-11-15

    The heat losses are mainly affects on the performance of cavity receiver of solar concentrator. In this paper, the experimental and numerical study is carried out for different heat losses from spherical cavity receiver of 0.385 m cavity diameter and 0.154 m opening diameter. The total and convection losses are studied experimentally to no wind and wind conditions for the temperature range of 150 °C to 300 °C at 0°, 30°, 45°, 60° and 90° inclination angle of cavity receiver. The experimental set up mainly consists of copper tube material cavity receiver wrapped with nichrome heating coil to heat the cavity and insulated with glasswool insulation. The numerical analysis was carried out with Fluent Computational fluid dynamics (CFD) software, to study connective heat losses for no wind condition only. The numerical results are compared with experimental results and found good agreement with maximum deviation of 12 %. The effect of inclination angle of cavity receiver on total losses and convection losses shows that as the inclination angle increases from 0o to 90o, both losses decreased due to decreased in convective zone into the cavity receiver. The effect of operating temperature of cavity shows that as the temperature of cavity receiver increases, the total and convective losses goes on increasing. The effect of external wind at 2 m/s and 4 m/s in two directions (side-on wind and head-on wind) is also studied experimentally for total and convective heat losses. The result shows that the heat losses are higher for head-on wind condition compared to side-on wind and no wind condition at all inclination angle of cavity receiver. The present results are also compared to the convective losses obtained from the correlations of Stine and Mcdonald and M. Prakash. The convective loss from these correlations shows nearest prediction to both experimental and numerical results.

  6. Heat loss investigation from spherical cavity receiver of solar concentrator

    International Nuclear Information System (INIS)

    Shewale, V. C.; Dongarwar, P. R.; Gawande, R. P.

    2016-01-01

    The heat losses are mainly affects on the performance of cavity receiver of solar concentrator. In this paper, the experimental and numerical study is carried out for different heat losses from spherical cavity receiver of 0.385 m cavity diameter and 0.154 m opening diameter. The total and convection losses are studied experimentally to no wind and wind conditions for the temperature range of 150 °C to 300 °C at 0°, 30°, 45°, 60° and 90° inclination angle of cavity receiver. The experimental set up mainly consists of copper tube material cavity receiver wrapped with nichrome heating coil to heat the cavity and insulated with glasswool insulation. The numerical analysis was carried out with Fluent Computational fluid dynamics (CFD) software, to study connective heat losses for no wind condition only. The numerical results are compared with experimental results and found good agreement with maximum deviation of 12 %. The effect of inclination angle of cavity receiver on total losses and convection losses shows that as the inclination angle increases from 0o to 90o, both losses decreased due to decreased in convective zone into the cavity receiver. The effect of operating temperature of cavity shows that as the temperature of cavity receiver increases, the total and convective losses goes on increasing. The effect of external wind at 2 m/s and 4 m/s in two directions (side-on wind and head-on wind) is also studied experimentally for total and convective heat losses. The result shows that the heat losses are higher for head-on wind condition compared to side-on wind and no wind condition at all inclination angle of cavity receiver. The present results are also compared to the convective losses obtained from the correlations of Stine and Mcdonald and M. Prakash. The convective loss from these correlations shows nearest prediction to both experimental and numerical results

  7. Design and manufacturing status of trim coils for the Wendelstein 7-X stellarator experiment

    Energy Technology Data Exchange (ETDEWEB)

    Riße, K., E-mail: konrad.risse@ipp.mpg.de [Max-Planck-Institut für Plasmaphysik, Greifswald (Germany); Rummel, Th.; Freundt, S.; Dudek, A.; Renard, S.; Bykov, V.; Köppen, M. [Max-Planck-Institut für Plasmaphysik, Greifswald (Germany); Langish, S.; Neilson, G.H.; Brown, Th.; Chrzanowski, J.; Mardenfeld, M.; Malinowski, F.; Khodak, A.; Zhao, X. [Princeton Plasma Physics Laboratory, Princeton, NJ (United States); Eksaa, G. [Everson Tesla Inc., Nazareth, PA (United States)

    2013-10-15

    Highlights: ► The trim coil system will fine tune the main magnetic field during plasma operation by reducing the magnetic field errors. ► The coil design and operational parameters are fixed, the manufacturing is running. ► The coils are equipped with temperature sensors and a voltage tap system to monitor the coil temperature. ► The max. operational deflection is in the order of 4.5 mm; the max. shearing stress across bond planes is of order 16 MPa. ► Special clamps equipped with elastomeric pads allow fixing the coils on the outer cryostat wall. -- Abstract: The stellarator fusion experiment Wendelstein 7-X (W7-X) is currently under construction at the Max-Planck-Institut für Plasmaphysik in Greifswald, Germany. The main magnetic field will be provided by a superconducting magnet system which generates a fivefold toroidal periodic magnetic field. However, unavoidable tolerances can result in small deviations of the magnetic field which disturb the toroidal periodicity. In order to have a tool to influence these field errors five additional normal conducting trim coils were designed to allow fine tuning of the main magnetic field during plasma operation. In the frame of an international cooperation the trim coils will be contributed by the US partners. Princeton Plasma Physics Laboratory has accomplished several tasks to develop the final design ready for manufacturing e.g. detailed manufacturing design for the winding and for the coil connection area. The design work was accompanied by a detailed analysis of resulting forces and moments to prove the design. The manufacturing of the coils is running at Everson Tesla Inc; the first two coils were received at IPP.

  8. Acoustic emission measurement on large scale coils at JAERI

    International Nuclear Information System (INIS)

    Yoshida, K.; Hattori, Y.; Nishi, M.F.; Shimamoto, S.; Tsuji, H.

    1986-01-01

    The objective of acoustic emission measurement at Japan Atomic Energy Research Institute (JAERI) is an establishment of a general diagnostic method for superconducting magnet systems. Output of strain and displacement gages can not cover a whole system in monitoring premonitory phenomena of a magnet system s failure, because these sensors are mounted on points and therefore localized. Acoustic emissions can be transmitted to sensors through structural materials without electrical noise. Monitoring of acoustic emission will be one of the methods to predict a serious failure of magnet systems in a vacuum vessel. For this purpose, several sensors were installed on the Japanese LCT coil and the Test Module Coil (TMC). Some of acoustic activity was similar as seen in these coils. The correlation between voltage spikes and acoustic events is excellent during single coil charging mode, but poorer during out of plane force mode. There are no indicative acoustical phenomena before a magnet quench or during normal zone generation. The conditioning of acoustic events and voltage spikes can be seen after any cooling down. The localization of electrical insulation damage with the acoustic emission technique is one of its most useful applications

  9. Control of intravascular catheters using an array of active steering coils.

    Science.gov (United States)

    Gudino, N; Heilman, J A; Derakhshan, J J; Sunshine, J L; Duerk, J L; Griswold, M A

    2011-07-01

    To extend the concept of deflecting the tip of a catheter with the magnetic force created in an MRI system through the use of an array of independently controllable steering coils located in the catheter tip, and to present methods for visualization of the catheter and/or surrounding areas while the catheter is deflected. An array of steering coils made of 42-gauge wire was built over a 2.5 Fr (0.83 mm) fiber braided microcatheter. Two of the coils were 70 turn axial coils separated by 1 cm, and the third was a 15-turn square side coil that was 2 x 4 mm2. Each coil was driven independently by a pulse width modulation (PWM) current source controlled by a microprocessor that received commands from a MATLAB routine that dynamically set current amplitude and direction for each coil. The catheter was immersed in a water phantom containing 1% Gd-DTPA that was placed at the isocenter of a 1.5 T MRI scanner. Deflections of the catheter tip were measured from image-based data obtained with a real-time radio frequency (RF) spoiled gradient echo sequence (GRE). The small local magnetic fields generated by the steering coils were exploited to generate a hyperintense signal at the catheter tip by using a modified GRE sequence that did not include slice-select rewinding gradients. Imaging and excitation modes were implemented by synchronizing the excitation of the steering coil array with the scanner by ensuring that no current was driven through the coils during the data acquisition window; this allowed visualization of the surrounding tissue while not affecting the desired catheter position. Deflections as large as 2.5 cm were measured when exciting the steering coils sequentially with a 100 mA maximum current per coil. When exciting a single axial coil, the deflection was half this value with 30% higher current. A hyperintense catheter tip useful for catheter tracking was obtained by imaging with the modified GRE sequence. Clear visualization of the areas surrounding the

  10. Development of a new error field correction coil (C-coil) for DIII-D

    International Nuclear Information System (INIS)

    Robinson, J.I.; Scoville, J.T.

    1995-12-01

    The C-coil recently installed on the DIII-D tokamak was developed to reduce the error fields created by imperfections in the location and geometry of the existing coils used to confine, heat, and shape the plasma. First results from C-coil experiments include stable operation in a 1.6 MA plasma with a density less than 1.0 x 10 13 cm -3 , nearly a factor of three lower density than that achievable without the C-coil. The C-coil has also been used in magnetic braking of the plasma rotation and high energy particle confinement experiments. The C-coil system consists of six individual saddle coils, each 60 degree wide toroidally, spanning the midplane of the vessel with a vertical height of 1.6 m. The coils are located at a major radius of 3.2 m, just outside of the toroidal field coils. The actual shape and geometry of each coil section varied somewhat from the nominal dimensions due to the large number of obstructions to the desired coil path around the already crowded tokamak. Each coil section consists of four turns of 750 MCM insulated copper cable banded with stainless steel straps within the web of a 3 in. x 3 in. stainless steel angle frame. The C-coil structure was designed to resist peak transient radial forces (up to 1,800 Nm) exerted on the coil by the toroidal and ploidal fields. The coil frames were supported from existing poloidal field coil case brackets, coil studs, and various other structures on the tokamak

  11. Argonne National Laboratory superconducting pulsed coil program

    International Nuclear Information System (INIS)

    Wang, S.T.; Kim, S.H.

    1979-01-01

    The main objectives are to develop high current (approx. 100 kA) cryostable cable configurations with reasonably low ac losses, to build a demonstration pulsed coil, and to develop a rather inexpensive large fiberglass reinforced helium cryostat. A 1.5-MJ cryostable pulsed superconducting coil has been developed and constructed at ANL. The coil has a peak field of 4.5 T at an operating current of 11.0 kA. A large inexpensive plastic cryostat has been developed for testing the pulsed coil. The coil has been pulsed with a maximum dB/dt of 11 T/s. The coil was pulsed more than 4000 cycles. Detailed results of the ac loss measurements and the current sharing of the cryostability will be described

  12. Test facility for PLT TF coils

    International Nuclear Information System (INIS)

    Hearney, J.; File, J.; Dreskin, S.

    1975-01-01

    Past experience with the model C stellerator and other toroidal field devices indicates that mechanical and electrical tests of a toroidal field coil prior to maximum field operation of the device is prudent and desirable. This paper describes a test program for the PLT-TF coils. The test stand consists of one test coil, two background coils and a steel supporting structure. The three coil configuration produces a 67.5 kG field at the inner conductor (38 kG at the bore center) and simulates a 1/R field distribution in the bore of the test coil. The resolution of the field force system and resultant stresses within the test structure are discussed. A test procedure is described which maximizes the information obtained from a 100,000 pulse program

  13. Power loss problems in EXTRAP coil systems

    International Nuclear Information System (INIS)

    Lehnert, B.

    1977-02-01

    The Ohmic power loss in the coils of external ring traps is minimized with respect to the thermonuclear power production. In the case of the DT-reaction this leads to dimensions and power densities being relevant to full-scale reactors. Not only superconducting or refrigerated coil windings can thus be used, but also hot-coil systems which are operated at several hundred degrees centrigrade and form part of a steam cycle and power extraction system. For hot coils the problems of void formation and tritium regeneration have to be further examined. The high beta value leads to moderately large coil stresses. Finally, replacement and repair become simplified by the present coil geometry. (Auth.)

  14. Coil supporting device for thermonuclear device

    International Nuclear Information System (INIS)

    Okubo, Minoru; Ando, Toshiro; Ota, Mitsuru; Ishimura, Masabumi.

    1979-01-01

    Purpose: To lower the bending stress exerted on coils thereby preventing the coils from deformation by branching the outer circumferential support frames of coil support frames disposed at an equal pitch circumferentially to the coils into plurality, and integrally forming them to the inner circumferential support frames. Constitution: Each of the support frames for supporting poloidal coils winding around a vacuum vessel is bisected at the radial midway so that the outer circumferential branches are disposed at an equal pitch and they are formed integrally with the inner circumferential support frames. The inner circumferential support frames are fixed by support posts on a bed and the outer circumferential support frames are mounted to the outer edge of wedge-like support posts. Accordingly, if the coils expand outwardly upon increase in the temperature, the stress exerted on the support frame can be decreased. (Yoshino, Y.)

  15. Split-coil-system SULTAN

    International Nuclear Information System (INIS)

    Vecsey, G.

    1992-08-01

    The high field superconductor test facility SULTAN started operation successfully in May 1992. Originally designed for testing full scale conductors for the large magnets of the next generation fusion reactors, the SULTAN facility installed at PSI (Switzerland) was designed as a common venture of three European Laboratories: ENEA (Italy), ECN (Netherlands) and PSI, and built by ENEA and PSI in the framework of the Euratom Fusion Technology Program. Presently the largest facility in the world, with its superconducting split coil system generating 11 Tesla in a 0.6 m bore, it is ready now for testing superconductor samples with currents up to 50 kA at variable cooling conditions. Similar tests can be arranged also for other applications. SULTAN is offered by the European Community as a contribution to the worldwide cooperation for the next step of fusion reactor development ITER. First measurements on conductor developed by CEA (Cadarache) are now in progress. Others like those of ENEA and CERN will follow. For 1993, a test of an Italian 12 TZ model coil for fusion application is planned. SULTAN is a worldwide unique facility marking the competitive presence of Swiss technology in the field of applied superconductivity research. Based on development and design of PSI, the high field Nb 3 Sn superconductors and coils were fabricated at the works of Kabelwerke Brugg and ABB, numerous Swiss companies contributed to the success of this international effort. Financing of the Swiss contribution of SULTAN was made available by NEFF, BEW, BBW, PSI and EURATOM. (author) figs., tabs., 20 refs

  16. Experimental and theoretical investigation of mechanical disturbances in epoxy-impregnated superconducting coils

    International Nuclear Information System (INIS)

    Iwasa, Y.; Bobrov, E.S.; Tsukamoto, O.; Takaghi, T.; Fujita, H.; Massachusetts Inst. of Tech., Cambridge

    1985-01-01

    The theoretical correlation between shear stress and epoxy resin fracture developed in an earlier paper was verified experimentally using a series of epoxy-impregnated, thin-walled superconducting test coils. In test coils with both ends rigidly clamped, cracks occurred as transport current was increased; during a training sequence the test was terminated by a premature quench. Using acoustic emission and voltage signals, each premature quench was linked directly to a crack occurring near one of the ends. Test coils which had both ends unsupported, giving the winding freedom to expand radially, did not experience epoxy fracture and showed no premature quenches. (author)

  17. DEVELOPMENT OF COILED TUBING STRESS ANALYSIS

    Directory of Open Access Journals (Sweden)

    Davorin Matanović

    1998-12-01

    Full Text Available The use of coiled tubing is increasing rapidly with drilling of horizontal wells. To satisfy all requirements (larger mechanical stresses, larger fluid capacities the production of larger sizes and better material qualities was developed. Stresses due to axial forces and pressures that coiled tubing is subjected are close to its performance limits. So it is really important to know and understand the behaviour of coiled tubing to avoid its break, burst or collapse in the well.

  18. Correlation between quantitative HER-2 protein expression and risk for brain metastases in HER-2+ advanced breast cancer patients receiving trastuzumab-containing therapy.

    Science.gov (United States)

    Duchnowska, Renata; Biernat, Wojciech; Szostakiewicz, Barbara; Sperinde, Jeff; Piette, Fanny; Haddad, Mojgan; Paquet, Agnes; Lie, Yolanda; Czartoryska-Arłukowicz, Bogumiła; Wysocki, Piotr; Jankowski, Tomasz; Radecka, Barbara; Foszczynska-Kłoda, Małgorzata; Litwiniuk, Maria; Debska, Sylwia; Weidler, Jodi; Huang, Weidong; Buyse, Marc; Bates, Michael; Jassem, Jacek

    2012-01-01

    Patients with human epidermal growth factor receptor (HER)-2+ breast cancer are at particularly high risk for brain metastases; however, the biological basis is not fully understood. Using a novel HER-2 assay, we investigated the correlation between quantitative HER-2 expression in primary breast cancers and the time to brain metastasis (TTBM) in HER-2+ advanced breast cancer patients treated with trastuzumab. The study group included 142 consecutive patients who were administered trastuzumab-based therapy for HER-2+ metastatic breast cancer. HER-2/neu gene copy number was quantified as the HER-2/centromeric probe for chromosome 17 (CEP17) ratio by central laboratory fluorescence in situ hybridization (FISH). HER-2 protein was quantified as total HER-2 protein expression (H2T) by the HERmark® assay (Monogram Biosciences, Inc., South San Francisco, CA) in formalin-fixed, paraffin-embedded tumor samples. HER-2 variables were correlated with clinical features and TTBM was measured from the initiation of trastuzumab-containing therapy. A higher H2T level (continuous variable) was correlated with shorter TTBM, whereas HER-2 amplification by FISH and a continuous HER-2/CEP17 ratio were not predictive (p = .013, .28, and .25, respectively). In the subset of patients that was centrally determined by FISH to be HER-2+, an above-the-median H2T level was significantly associated with a shorter TTBM (hazard ratio, [HR], 2.4; p = .005), whereas this was not true for the median HER-2/CEP17 ratio by FISH (p = .4). Correlation between a continuous H2T level and TTBM was confirmed on multivariate analysis (HR, 3.3; p = .024). These data reveal a strong relationship between the quantitative HER-2 protein expression level and the risk for brain relapse in HER-2+ advanced breast cancer patients. Consequently, quantitative assessment of HER-2 protein expression may inform and facilitate refinements in therapeutic treatment strategies for selected subpopulations of patients in this

  19. Manufacturing development of the Westinghouse Nb3Sn coil for the Large Coil Test Program

    International Nuclear Information System (INIS)

    Young, J.L.; Vota, T.L.; Singh, S.K.

    1983-01-01

    The Westinghouse Nb 3 Sn Magnet for the Oak Ridge National Laboratory Large Coil Program (LCP) is currently well into the manufacturing phase. This paper identifies the manufacturing processes and development tasks for his unique, advanced coil

  20. Optimization of the ECT background coil

    International Nuclear Information System (INIS)

    Ballou, J.K.; Luton, J.N.

    1975-01-01

    This study was begun to optimize the Eccentric Coil Test (ECT) background coil. In the course of this work a general optimization code was obtained, tested, and applied to the ECT problem. So far this code has proven to be very satisfactory. The results obtained with this code and earlier codes have illustrated the parametric behavior of such a coil system and that the optimum for this type system is broad. This study also shows that a background coil with a winding current density of less than 3000 A/cm 2 is not feasible for the ECT models presented in this paper

  1. Magnetic field coil in nuclear fusion device

    International Nuclear Information System (INIS)

    Yamaguchi, Mitsugi; Takano, Hirohisa.

    1975-01-01

    Object: To provide an electrical-insulatively stabilized magnetic field coil in nuclear fusion device, restraining an increase in voltage when plasma current is rapidly changed. Structure: A magnetic field coil comprises coils arranged coaxial with respective vacuum vessels, said coils being wound in positive and reverse polarities so as to form a vertical magnetic field within the plasma. The coils of the positive polarity are arranged along the vacuum vessel inside of an axis vertical in section of the annular plasma and are arranged symmetrically up and down of a horizontal axis. On the other hand, the coils of the reverse polarity are arranged along the vacuum vessel outside of a vertical axis and arranged symmetrically up and down of the horizontal axis. These positive and reverse polarity coils are alternately connected in series, and lead portions of the coils are connected to a power source by means of connecting wires. In this case, lead positions of the coils are arranged in one direction, and the connecting wires are disposed in closely contact relation to offset magnetic fields formed by the connecting wires each other. (Kawakami, Y.)

  2. A precise technique for manufacturing correction coil

    International Nuclear Information System (INIS)

    Schieber, L.

    1992-01-01

    An automated method of manufacturing correction coils has been developed which provides a precise embodiment of the coil design. Numerically controlled machines have been developed to accurately position coil windings on the beam tube. Two types of machines have been built. One machine bonds the wire to a substrate which is wrapped around the beam tube after it is completed while the second machine bonds the wire directly to the beam tube. Both machines use the Multiwire reg-sign technique of bonding the wire to the substrate utilizing an ultrasonic stylus. These machines are being used to manufacture coils for both the SSC and RHIC

  3. Tesla coil theoretical model and experimental verification

    OpenAIRE

    Voitkans, Janis; Voitkans, Arnis

    2014-01-01

    Abstract – In this paper a theoretical model of a Tesla coil operation is proposed. Tesla coil is described as a long line with distributed parameters in a single-wired format, where the line voltage is measured against electrically neutral space. It is shown that equivalent two-wired scheme can be found for a single-wired scheme and already known long line theory can be applied to a Tesla coil. Formulas for calculation of voltage in a Tesla coil by coordinate and calculation of resonance fre...

  4. Modeling of an once through helical coil steam generator of a superheated cycle for sizing analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yeon Sik; Sim, Yoon Sub; Kim, Eui Kwang [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1997-12-31

    A thermal sizing code, named as HSGSA (Helical coil Steam Generator Sizing Analyzer), for a sodium heated helical coil steam generator is developed for KALIMER (Korea Advanced LIquid MEtal Reactor) design. The theoretical modeling of the shell and tube sides is described and relevant correlations are presented. For assessment of HSGSA, a reference plant design case is compared to the calculational outputs from HSGSA simulation. 9 refs., 6 figs. (Author)

  5. Modeling of an once through helical coil steam generator of a superheated cycle for sizing analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yeon Sik; Sim, Yoon Sub; Kim, Eui Kwang [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1998-12-31

    A thermal sizing code, named as HSGSA (Helical coil Steam Generator Sizing Analyzer), for a sodium heated helical coil steam generator is developed for KALIMER (Korea Advanced LIquid MEtal Reactor) design. The theoretical modeling of the shell and tube sides is described and relevant correlations are presented. For assessment of HSGSA, a reference plant design case is compared to the calculational outputs from HSGSA simulation. 9 refs., 6 figs. (Author)

  6. Superconducting Coil of Po Dipole

    CERN Multimedia

    1983-01-01

    The Po superconducting dipole was built as a prototype beam transport magnet for the SPS extracted proton beam P0. Its main features were: coil aperture 72 mm, length 5 m, room-temperature yoke, NbTi cable conductor impregnated with solder, nominal field 4.2 T at 4.7 K (87% of critical field). It reached its nominal field without any quench.After this successful test up to its nominal field of 4.2 T, the power was not raised to reach a quench. The magnet was not installed in a beam and had no other further use. Nevertheless its construction provided knowledges and experience which became useful in the design and construction of the LHC magnets. The photo shows a detail of the inner layer winding before superposing the outer layer to form the complete coil of a pole. Worth noticing is the interleaved glass-epoxy sheet (white) with grooved channels for the flow of cooling helium. See also 8211532X.

  7. Design of the coolant system for the Large Coil Test Facility pulse coils

    International Nuclear Information System (INIS)

    Bridgman, C.; Ryan, T.L.

    1983-01-01

    The pulse coils will be a part of the Large Coil Test Facility in Oak Ridge, Tennessee, which is designed to test six large tokamak-type superconducting coils. The pulse coil set consists of two resistive coaxial solenoid coils, mounted so that their magnetic axis is perpendicular to the toroidal field lines of the test coil. The pulse coils provide transient vertical fields at test coil locations to simulate the pulsed vertical fields present in tokamak devices. The pulse coils are designed to be pulsed for 30 s every 150 s, which results in a Joule heating of 116 kW per coil. In order to provide this capability, the pulse coil coolant system is required to deliver 6.3 L/s (100 gpm) of subcooled liquid nitrogen at 10-atm absolute pressure. The coolant system can also cool down each pulse coil from room temperature to liquid nitrogen temperature. This paper provides details of the pumping and heat exchange equipment designed for the coolant system and of the associated instrumentation and controls

  8. An experimental study of thermal characterization of parabolic trough receivers

    International Nuclear Information System (INIS)

    Lei, Dongqiang; Li, Qiang; Wang, Zhifeng; Li, Jian; Li, Jianbin

    2013-01-01

    Highlights: ► A new test stand of heat loss has been developed at IEECAS. ► A correlation between heat loss and absorber temperature is presented, 270 W/m 400 °C. ► The ratio of end loss in total heat loss increases with decreasing the temperature. ► The emittance test stand using a high vacuum system and vacuum gauge is built. ► Emittance first decreases, then rapidly increases with increasing the temperature. - Abstract: The receiver is a key component of the parabolic trough solar station. The receiver requires the most challenging technology and has a decisive influence on the thermal and economic performance of a power plant. The Institute of Electrical Engineering Chinese Academy Sciences (IEECAS) and Himin Solar Co., Ltd. (HSC) cooperated to develop solar receivers for the first 50 MW parabolic trough project in Inner Mongolia, China. This paper examines overall heat loss, end loss and thermal emittance of the coating of a newly designed receiver in order to evaluate its thermal characterization. A series of heat loss tests are conducted in a newly developed test stand following the steady state equilibrium method. The tests provide a correlation between heat loss and the absorber temperature. This paper presents a new testing method to accurately test the coating emittance. The method uses a receiver with a high vacuum system and a vacuum gauge to maintain continuous exhaust and high vacuum throughout the heat loss testing. A heat loss comparison between the receiver and other existing receivers provides a reference that enabled further optimization. Theoretical and experimental analysis examines the effects of end loss both with and without a heat insulator and a coil heater. The emittance curves of different coatings are acquired and the reasons for initial emittance decrease and then remarkable increase versus temperature are analyzed

  9. Measurement of heating coil temperature for e-cigarettes with a "top-coil" clearomizer.

    Science.gov (United States)

    Chen, Wenhao; Wang, Ping; Ito, Kazuhide; Fowles, Jeff; Shusterman, Dennis; Jaques, Peter A; Kumagai, Kazukiyo

    2018-01-01

    To determine the effect of applied power settings, coil wetness conditions, and e-liquid compositions on the coil heating temperature for e-cigarettes with a "top-coil" clearomizer, and to make associations of coil conditions with emission of toxic carbonyl compounds by combining results herein with the literature. The coil temperature of a second generation e-cigarette was measured at various applied power levels, coil conditions, and e-liquid compositions, including (1) measurements by thermocouple at three e-liquid fill levels (dry, wet-through-wick, and full-wet), three coil resistances (low, standard, and high), and four voltage settings (3-6 V) for multiple coils using propylene glycol (PG) as a test liquid; (2) measurements by thermocouple at additional degrees of coil wetness for a high resistance coil using PG; and (3) measurements by both thermocouple and infrared (IR) camera for high resistance coils using PG alone and a 1:1 (wt/wt) mixture of PG and glycerol (PG/GL). For single point thermocouple measurements with PG, coil temperatures ranged from 322 ‒ 1008°C, 145 ‒ 334°C, and 110 ‒ 185°C under dry, wet-through-wick, and full-wet conditions, respectively, for the total of 13 replaceable coil heads. For conditions measured with both a thermocouple and an IR camera, all thermocouple measurements were between the minimum and maximum across-coil IR camera measurements and equal to 74% ‒ 115% of the across-coil mean, depending on test conditions. The IR camera showed details of the non-uniform temperature distribution across heating coils. The large temperature variations under wet-through-wick conditions may explain the large variations in formaldehyde formation rate reported in the literature for such "top-coil" clearomizers. This study established a simple and straight-forward protocol to systematically measure e-cigarette coil heating temperature under dry, wet-through-wick, and full-wet conditions. In addition to applied power, the

  10. Progress on large superconducting toroidal field coils

    International Nuclear Information System (INIS)

    Haubenreich, P.N.; Luton, J.N.; Thompson, P.B.; Beard, D.S.

    1979-01-01

    Large superconducting toroidal field coils of competing designs are being produced by six major industrial teams. In the US, teams headed by General Dynamics Convair, General Electric, and Westinghouse are under contract to design and fabricate one coil each to specifications established by the Large Coil Program. A facility for testing 6 coils in a toroidal array at fields to 8 to 12 tesla is under construction at Oak Ridge. Through an international agreement, EURATOM, Japan, and Switzerland will produce one coil each for testing with the US coils. Each test coil will have a 2.5 x 3.5 m D-shape winding bore and is designed to operate at a current of 10 to 18 kA at a peak field of 8T while subjected to pulsed fields of 0.14 T applied in 1.0 s. There are significant differences among the six coil designs: five use NbTi, one Nb 3 Sn; three are cooled by pool boiling helium, three by forced flow; five have welded or bolted stainless steel coil cases, one has aluminum plate structure. All are designed to be cryostable at 8T, with structural margin for extended operation. The three US coil teams are almost or completely finished with detailed design and are now procuring materials and setting up manufacturing equipment. The non-US teams are at various stages of verification testing and design. The GDC and GE coils are scheduled for delivery in the spring of 1981 and the others will be completed a year later. The 11-m diameter vessel at the test facility has been completed and major components of the test stand are being procured. Engineering and procurement to upgrade the helium liquifier-refrigerator system are under way

  11. Increased Vessel Depiction of the Carotid Bifurcation with a Specialized 16-Channel Phased Array Coil at 3T

    Science.gov (United States)

    Tate, Quinn; Kim, Seong-Eun; Treiman, Gerald; Parker, Dennis L.; Hadley, J. Rock

    2012-01-01

    The purpose of this work was to design and construct a multi-channel receive-only RF coil for 3 Tesla magnetic resonance imaging of the human carotid artery and bifurcation with optimized signal to noise ratio in the carotid vessels along the full extent of the neck. A neck phantom designed to match the anatomy of a subject with a neck representing the body habitus often seen in subjects with carotid arterial disease, was constructed. Sixteen circular coil elements were arranged on a semi-rigid fiberglass former that closely fit the shape of the phantom, resulting in a 16-channel bilateral phased array coil. Comparisons were made between this coil and a typical 4-channel carotid coil in a study of 10 carotid vessels in 5 healthy volunteers. The 16-channel carotid coil showed a 73% average improvement in signal to noise ratio (SNR) at the carotid bifurcation. This coil also maintained an SNR greater than the peak SNR of the 4-channel coil over a vessel length of 10 cm. The resulting increase in SNR improved vessel depiction of the carotid arteries over an extended field of view, and demonstrated better image quality for higher parallel imaging reduction factors compared to the 4-channel coil. PMID:22777692

  12. A 32-channel lattice transmission line array for parallel transmit and receive MRI at 7 tesla.

    Science.gov (United States)

    Adriany, Gregor; Auerbach, Edward J; Snyder, Carl J; Gözübüyük, Ark; Moeller, Steen; Ritter, Johannes; Van de Moortele, Pierre-François; Vaughan, Tommy; Uğurbil, Kâmil

    2010-06-01

    Transmit and receive RF coil arrays have proven to be particularly beneficial for ultra-high-field MR. Transmit coil arrays enable such techniques as B(1) (+) shimming to substantially improve transmit B(1) homogeneity compared to conventional volume coil designs, and receive coil arrays offer enhanced parallel imaging performance and SNR. Concentric coil arrangements hold promise for developing transceiver arrays incorporating large numbers of coil elements. At magnetic field strengths of 7 tesla and higher where the Larmor frequencies of interest can exceed 300 MHz, the coil array design must also overcome the problem of the coil conductor length approaching the RF wavelength. In this study, a novel concentric arrangement of resonance elements built from capacitively-shortened half-wavelength transmission lines is presented. This approach was utilized to construct an array with whole-brain coverage using 16 transceiver elements and 16 receive-only elements, resulting in a coil with a total of 16 transmit and 32 receive channels. (c) 2010 Wiley-Liss, Inc.

  13. Mid-range adiabatic wireless energy transfer via a mediator coil

    International Nuclear Information System (INIS)

    Rangelov, A.A.; Vitanov, N.V.

    2012-01-01

    A technique for efficient mid-range wireless energy transfer between two coils via a mediator coil is proposed. By varying the coil frequencies, three resonances are created: emitter–mediator (EM), mediator–receiver (MR) and emitter–receiver (ER). If the frequency sweeps are adiabatic and such that the EM resonance precedes the MR resonance, the energy flows sequentially along the chain emitter–mediator–receiver. If the MR resonance precedes the EM resonance, then the energy flows directly from the emitter to the receiver via the ER resonance; then the losses from the mediator are suppressed. This technique is robust against noise, resonant constraints and external interferences. - Highlights: ► Efficient and robust mid-range wireless energy transfer via a mediator coil. ► The adiabatic energy transfer is analogous to adiabatic passage in quantum optics. ► Wireless energy transfer is insensitive to any resonant constraints. ► Wireless energy transfer is insensitive to noise in the neighborhood of the coils.

  14. Outcomes with single-coil versus dual-coil implantable cardioverter defibrillators: a meta-analysis.

    Science.gov (United States)

    Sunderland, Nicholas; Kaura, Amit; Murgatroyd, Francis; Dhillon, Para; Scott, Paul A

    2018-03-01

    Dual-coil implantable cardioverter defibrillator (ICD) leads have traditionally been used over single-coil leads due to concerns regarding high defibrillation thresholds (DFT) and consequent poor shock efficacy. However, accumulating evidence suggests that this position may be unfounded and that dual-coil leads may also be associated with higher complication rates during lead extraction. This meta-analysis collates data comparing dual- and single-coil ICD leads. Electronic databases were systematically searched for randomized controlled trials (RCT) and non-randomized studies comparing single-coil and dual-coil leads. The mean differences in DFT and summary estimates of the odds-ratio (OR) for first-shock efficacy and the hazard-ratio (HR) for all-cause mortality were calculated using random effects models. Eighteen studies including a total of 138,124 patients were identified. Dual-coil leads were associated with a lower DFT compared to single coil leads (mean difference -0.83J; 95% confidence interval [CI] -1.39--0.27; P = 0.004). There was no difference in the first-shock success rate with dual-coil compared to single-coil leads (OR 0.74; 95%CI 0.45-1.21; P=0.22). There was a significantly lower risk of all-cause mortality associated with single-coil leads (HR 0.91; 95%CI 0.86-0.95; P dual-coil leads. The mortality benefit with single-coil leads most likely represents patient selection bias. Given the increased risk and complexity of extracting dual-coil leads, centres should strongly consider single-coil ICD leads as the lead of choice for routine new left-sided ICD implants. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2017. For permissions, please email: journals.permissions@oup.com.

  15. HydroCoil as an adjuvant to bare platinum coil treatment of 100 cerebral aneurysms

    International Nuclear Information System (INIS)

    Fanning, Noel F.; Berentei, Zsolt; Brennan, Paul R.; Thornton, John

    2007-01-01

    Introduction The overall safety of the HydroCoil, an expansile hybrid hydrogel-platinum coil, is unknown. We report a prospective observational study of our first 100 cerebral aneurysms treated with HydroCoils, focusing on safety and initial efficacy.Methods Indications, procedural complications, clinical and angiographic outcomes were recorded. Packing density, number of coils deployed and angiographic results were compared with those in a matched control group of 100 aneurysms treated solely with bare platinum coils. HydroCoil complication rates were compared to bare platinum coil rates at our institution and in published series. Results Adjuvant HydroCoil treatment led to increased mean percentage aneurysm filling compared to controls (50 ± 21% versus 27 ± 13%, P < 0.001). Immediate posttreatment angiographic results showed significantly (P < 0.001) more complete occlusions and fewer incomplete (<95%) occlusions compared to controls. Intermediate follow-up angiograms (median 7.5 months) in 63 aneurysms showed a trend towards fewer incomplete occlusions with HydroCoil treatment. There were significantly fewer major recurrences with HydroCoil treatment compared to the control treatment (9.5% versus 22.6%, P 0.046). In the adjuvant HydroCoil group, major recurrent aneurysms had significantly less percentage volume packing with HydroCoils than non-recurrent aneurysms (50.3 ± 5.0% versus 65.3 ± 18.0%, P = 0.04). There was a 12% procedural complication rate, 6% procedural morbidity and 1% mortality rate, similar to institutional and reported bare platinum coil complication rates.Conclusion HydroCoils can be safely deployed with a similar complication rate to bare platinum coils. They result in improved aneurysm filling. Intermediate follow-up angiography showed significantly fewer major recurrences. Long-term follow-up is required to confirm initial improved stability. (orig.)

  16. Analysis and Optimization of Four-Coil Planar Magnetically Coupled Printed Spiral Resonators

    Directory of Open Access Journals (Sweden)

    Sadeque Reza Khan

    2016-08-01

    Full Text Available High-efficiency power transfer at a long distance can be efficiently established using resonance-based wireless techniques. In contrast to the conventional two-coil-based inductive links, this paper presents a magnetically coupled fully planar four-coil printed spiral resonator-based wireless power-transfer system that compensates the adverse effect of low coupling and improves efficiency by using high quality-factor coils. A conformal architecture is adopted to reduce the transmitter and receiver sizes. Both square architecture and circular architectures are analyzed and optimized to provide maximum efficiency at a certain operating distance. Furthermore, their performance is compared on the basis of the power-transfer efficiency and power delivered to the load. Square resonators can produce higher measured power-transfer efficiency (79.8% than circular resonators (78.43% when the distance between the transmitter and receiver coils is 10 mm of air medium at a resonant frequency of 13.56 MHz. On the other hand, circular coils can deliver higher power (443.5 mW to the load than the square coils (396 mW under the same medium properties. The performance of the proposed structures is investigated by simulation using a three-layer human-tissue medium and by experimentation.

  17. Analysis of transmission efficiency of the superconducting resonance coil according the materials of cooling system

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Yu Kyeong; Hwang, Jun Won; Choi, Hyo Sang [Chosun University, Gwangju (Korea, Republic of)

    2016-03-15

    The wireless power transfer (WPT) system using a magnetic resonance was based on magnetic resonance coupling of the transmission and the receiver coils. In these system, it is important to maintain a high quality-factor (Q-factor) to increase the transmission efficiency of WPT system. Our research team used a superconducting coil to increase the Q-factor of the magnetic resonance coil in WPT system. When the superconductor is applied in these system, we confirmed that transmission efficiency of WPT system was higher than normal conductor coil through a preceding study. The efficiency of the transmission and the receiver coil is affected by the magnetic shielding effect of materials around the coils. The magnetic shielding effect is dependent on the type, thickness, frequency, distance, shape of materials. Therefore, it is necessary to study the WPT system on the basis of these conditions. In this paper, the magnetic shield properties of the cooling system were analyzed using the High-Frequency Structure Simulation (HFSS, Ansys) program. We have used the shielding materials such as plastic, aluminum and iron, etc. As a result, when we applied the fiber reinforced polymer (FRP), the transmission efficiency of WPT was not affected because electromagnetic waves went through the FRP. On the other hand, in case of a iron and aluminum, transmission efficiency was decreased because of their electromagnetic shielding effect. Based on these results, the research to improve the transmission efficiency and reliability of WPT system is continuously necessary.

  18. Analysis and Optimization of Four-Coil Planar Magnetically Coupled Printed Spiral Resonators.

    Science.gov (United States)

    Khan, Sadeque Reza; Choi, GoangSeog

    2016-08-03

    High-efficiency power transfer at a long distance can be efficiently established using resonance-based wireless techniques. In contrast to the conventional two-coil-based inductive links, this paper presents a magnetically coupled fully planar four-coil printed spiral resonator-based wireless power-transfer system that compensates the adverse effect of low coupling and improves efficiency by using high quality-factor coils. A conformal architecture is adopted to reduce the transmitter and receiver sizes. Both square architecture and circular architectures are analyzed and optimized to provide maximum efficiency at a certain operating distance. Furthermore, their performance is compared on the basis of the power-transfer efficiency and power delivered to the load. Square resonators can produce higher measured power-transfer efficiency (79.8%) than circular resonators (78.43%) when the distance between the transmitter and receiver coils is 10 mm of air medium at a resonant frequency of 13.56 MHz. On the other hand, circular coils can deliver higher power (443.5 mW) to the load than the square coils (396 mW) under the same medium properties. The performance of the proposed structures is investigated by simulation using a three-layer human-tissue medium and by experimentation.

  19. A Flexible Nested Sodium and Proton Coil Array with Wideband Matching for Knee Cartilage MRI at 3 Tesla

    Science.gov (United States)

    Brown, Ryan; Lakshmanan, Karthik; Madelin, Guillaume; Alon, Leeor; Chang, Gregory; Sodickson, Daniel K.; Regatte, Ravinder R.; Wiggins, Graham C.

    2015-01-01

    Purpose We describe a 6×2 channel sodium/proton array for knee MRI at 3 Tesla. Multi-element coil arrays are desirable because of well-known signal-to-noise ratio advantages over volume and single-element coils. However, low coil-tissue coupling that is characteristic of coils operating at low frequency can make the potential gains from a phased array difficult to realize. Methods The issue of low coil-tissue coupling in the developed six channel sodium receive array was addressed by implementing 1) a mechanically flexible former to minimize coil-to-tissue distance and reduce the overall diameter of the array and 2) a wideband matching scheme that counteracts preamplifier noise degradation caused by coil coupling and a high quality factor. The sodium array was complemented with a nested proton array to enable standard MRI. Results The wideband matching scheme and tight-fitting mechanical design contributed to greater than 30% central SNR gain on the sodium module over a mono-nuclear sodium birdcage coil, while the performance of the proton module was sufficient for clinical imaging. Conclusion We expect the strategies presented in this work to be generally relevant in high density receive arrays, particularly in x-nuclei or small animal applications, or in those where the array is distant from the targeted tissue. PMID:26502310

  20. Toroidal field coils for the PDX machine

    International Nuclear Information System (INIS)

    Bushnell, C.W.

    1975-01-01

    This paper describes the engineering design features of the TF coils for the PDX machine. Included are design details of the electrical insulation, water cooling, and coil segment joint which allows access to the central machine area. A discussion of the problems anticipated in the manufacture and the planned solutions are presented

  1. Operator coil monitoring Acceptance Test Procedure

    International Nuclear Information System (INIS)

    Erhart, M.F.

    1995-01-01

    The readiness of the Data Acquisition and Control System (DACS) to provide monitoring and control of the Programmable Logic Controller (PLC) abort coils from the Master and RSS stations will be systematically tested during performance of this procedure. It should be noted that these are not physical abort coils but software coils controlled by the software's ladder logic. The readiness of the DACS to properly interface with the ENRAF wire level gauge installed in the SY-101 storage tank will also be tested. During this test, a verification of all abort coil indications will be conducted at the DACS Development Facility in the 306E Building by injecting an input signal for each DACS sensor that has an associated abort coil until the abort coil actuates, and then ensuring that the status of the abort coil indicated at the Master and RSS stations is correct. Each abort coil will also be tested to ensure that the ''ENABLE'' and ''DISABLE'' controls from the Master and RSS stations function correctly, and only with the use of proper passwords

  2. Coil Optimization for High Temperature Superconductor Machines

    DEFF Research Database (Denmark)

    Mijatovic, Nenad; Jensen, Bogi Bech; Abrahamsen, Asger Bech

    2011-01-01

    This paper presents topology optimization of HTS racetrack coils for large HTS synchronous machines. The topology optimization is used to acquire optimal coil designs for the excitation system of 3 T HTS machines. Several tapes are evaluated and the optimization results are discussed. The optimiz...

  3. Novel transcranial magnetic stimulation coil for mice

    Science.gov (United States)

    March, Stephen; Stark, Spencer; Crowther, Lawrence; Hadimani, Ravi; Jiles, David

    2014-03-01

    Transcranial magnetic stimulation (TMS) shows potential for non-invasive treatment of various neurological disorders. Significant work has been performed on the design of coils used for TMS on human subjects but few reports have been made on the design of coils for use on the brains of animals such as mice. This work is needed as TMS studies utilizing mice can allow rapid preclinical development of TMS for human disorders but the coil designs developed for use on humans are inadequate for optimal stimulation of the much smaller mouse brain. A novel TMS coil has been developed with the goal of inducing strong and focused electric fields for the stimulation of small animals such as mice. Calculations of induced electric fields were performed utilizing an MRI derived inhomogeneous model of an adult male mouse. Mechanical and thermal analysis of this new TMS helmet-coil design have also been performed at anticipated TMS operating conditions to ensure mechanical stability of the new coil and establish expected linear attraction and rotational force values. Calculated temperature increases for typical stimulation periods indicate the helmet-coil system is capable of operating within established medical standards. A prototype of the coil has been fabricated and characterization results are presented.

  4. The bar coil for NMR tomograph

    International Nuclear Information System (INIS)

    Bogorodzki, P.; Piatkowski, A.; Wasielewski, J.

    1995-01-01

    The bar coil (bi-planar) for the NMR tomograph, designed for medical diagnostics, has been described. The tests of coil shown that it generates good homogenous magnetic field in a big volume what results in improving of the signal-to-noise ratio

  5. Evidence-based pathology: umbilical cord coiling.

    Science.gov (United States)

    Khong, T Y

    2010-12-01

    The generation of a pathology test result must be based on criteria that are proven to be acceptably reproducible and clinically relevant to be evidence-based. This review de-constructs the umbilical cord coiling index to illustrate how it can stray from being evidence-based. Publications related to umbilical cord coiling were retrieved and analysed with regard to how the umbilical coiling index was calculated, abnormal coiling was defined and reference ranges were constructed. Errors and other influences that can occur with the measurement of the length of the umbilical cord or of the number of coils can compromise the generation of the coiling index. Definitions of abnormal coiling are not consistent in the literature. Reference ranges defining hypocoiling or hypercoiling have not taken those potential errors or the possible effect of gestational age into account. Even the way numerical test results in anatomical pathology are generated, as illustrated by the umbilical coiling index, warrants a critical analysis into its evidence base to ensure that they are reproducible or free from errors.

  6. Composite coils for toroidal field coils and method of using same

    International Nuclear Information System (INIS)

    Perkins, R. G.; Trujillo, S. M.

    1985-01-01

    A composite toroidal field (TF) generating means consisting of segmented magnetic coil windings is disclosed. Each coil winding of the TF generating means consists of a copper or copper alloy conductor segment and an aluminum or aluminum alloy conductor segment. The conductor segments are joined at a high strength, low electrical resistance joint and the joint may either be a mechanical or metallurgical one. The use of the aluminum or aluminum alloy conductor segments improves the neutron economy of the reactor with which the TF coil is associated and reduces TF coil nuclear heating and heating gradients, and activation in the TF coils

  7. Effect of γ-Al2O3/water nanofluid on the thermal performance of shell and coil heat exchanger with different coil torsions

    Science.gov (United States)

    Elshazly, K. M.; Sakr, R. Y.; Ali, R. K.; Salem, M. R.

    2017-06-01

    This work investigated experimentally the thermal performance of shell and coil heat exchanger with different coil torsions (λ) for γ-Al2O3/water nanofluid flow. Five helically coiled tube (HCT) with 0.0442 ≤ λ ≤ 0.1348 were tested within turbulent flow regime. The average size of γ-Al2O3 particles is 40 nm and volume concentration (φ) is varied from 0 to 2%. Results showed that reducing coil torsion enhances the heat transfer rate and increases HCT-friction factor (fc). Also, it is noticed that HCT average Nusselt number (Nut) and fc of nanofluids increase with increasing γ-Al2O3 volume concentration. The thermal performance index, TPI = (ht,nf/ht,bf)/(ΔPc,nf/ΔPc,bf). increases with increasing nanoparticles concentration, coil torsion, HCT-side inlet temperature and nanofluid flow rate. Over the studied range of HCT-Reynolds number, the average value of TPI is of 1.34 and 2.24 at φ = 0.5% and φ = 2%, respectively. The average value of TPI is of 1.64 at λ = 0.0442 while its average value at λ = 0.1348 is of 2.01. One of the main contributions is to provide heat equipments designers with Nut and fc correlations for practical configurations shell and coil heat exchangers with a wide range of nanofluid concentration.

  8. Startup of Large Coil Test Facility

    International Nuclear Information System (INIS)

    Haubenreich, P.N.; Bohanan, R.E.; Fietz, W.A.; Luton, J.N.; May, J.R.

    1984-01-01

    The Large Coil Test Facility (LCTF) is being used to test superconducting toroidal field coils about one-third the size of those for INTOR. Eventually, six different coils from four countries will be tested. Operations began in 1983 with acceptance testing of the helium refrigerator/liquefier system. Comprehensive shakedown of the facility and tests with the first three coils (from Japan, the United States, and Switzerland) were successfully accomplished in the summer of 1984. Currents up to 10,200 A and fields up to 6.4 T were reached. Data were obtained on performance of refrigerator, helium distribution, power supplies, controls, and data acquisition systems and on the acoustic emission, voltages, currents, and mechanical strains during charging and discharging the coils

  9. Startup of Large Coil Test Facility

    International Nuclear Information System (INIS)

    Haubenreich, P.N.; Bohanan, R.E.; Fietz, W.A.; Luton, J.N.; May, J.R.

    1985-01-01

    The Large Coil Test Facility (LCTF) is being used to test superconducting toroidal field coils about one-third the size of those for INTOR. Eventually, six different coils from four countries will be tested. Operations began in 1983 with acceptance testing of the helium refrigerator/liquefier system. Comprehensive shakedown of the facility and tests with the first three coils (from Japan, the United States, and Switzerland) were successfully accomplished in the summer of 1984. Currents up to 10,200 A and fields up to 6.4 T were reached. Data were obtained on performance of refrigerator, helium distribution, power supplies, controls, and data acquisition systems and on the acoustic emission, voltages, currents, and mechanical strains during charging and discharging the coils

  10. Helically coiled tube heat exchanger

    International Nuclear Information System (INIS)

    Harris, A.M.

    1981-01-01

    In a heat exchanger such as a steam generator for a nuclear reactor, two or more bundles of helically coiled tubes are arranged in series with the tubes in each bundle integrally continuing through the tube bundles arranged in series therewith. Pitch values for the tubing in any pair of tube bundles, taken transverse to the path of the reactor coolant flow about the tubes, are selected as a ratio of two unequal integers to permit efficient operation of each tube bundle while maintaining the various tube bundles of the heat exchanger within a compact envelope. Preferably, the helix angle and tube pitch parallel to the path of coolant flow are constant for all tubes in a single bundle so that the tubes are of approximately the same length within each bundle

  11. Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration

    Directory of Open Access Journals (Sweden)

    Soo-Yon Rhee

    2017-04-01

    Full Text Available Tenofovir disoproxil fumarate (TDF genotypic resistance defined by K65R/N and/or K70E/Q/G occurs in 20% to 60% of individuals with virological failure (VF on a WHO-recommended TDF-containing first-line regimen. However, the full spectrum of reverse transcriptase (RT mutations selected in individuals with VF on such a regimen is not known. To identify TDF regimen-associated mutations (TRAMs, we compared the proportion of each RT mutation in 2873 individuals with VF on a WHO-recommended first-line TDF-containing regimen to its proportion in a cohort of 50,803 antiretroviral-naïve individuals. To identify TRAMs specifically associated with TDF-selection pressure, we compared the proportion of each TRAM to its proportion in a cohort of 5805 individuals with VF on a first-line thymidine analog-containing regimen. We identified 83 TRAMs including 33 NRTI-associated, 40 NNRTI-associated, and 10 uncommon mutations of uncertain provenance. Of the 33 NRTI-associated TRAMs, 12 – A62V, K65R/N, S68G/N/D, K70E/Q/T, L74I, V75L, and Y115F – were more common among individuals receiving a first-line TDF-containing compared to a first-line thymidine analog-containing regimen. These 12 TDF-selected TRAMs will be important for monitoring TDF-associated transmitted drug-resistance and for determining the extent of reduced TDF susceptibility in individuals with VF on a TDF-containing regimen.

  12. Effects of passive coils on spheromak gross MHD instabilities

    International Nuclear Information System (INIS)

    Munson, C.; Janos, A.; Paul, S.; Wysocki, F.; Yamada, M.

    1983-01-01

    The experimental investigation of the effectiveness of figure-8 coils in stabilizing the n=1 tilting mode of spheromak plasmas in Proto S-1 A/B is extended. In addition, another coil configuration, the saddle coil, is examined

  13. Abciximab for thrombolysis during intracranial aneurysm coiling

    International Nuclear Information System (INIS)

    Gralla, Jan; Rennie, Adam T.M.; Corkill, Rufus A.; Lalloo, Shivendra T.; Molyneux, Andrew; Byrne, James V.; Kuker, Wilhem

    2008-01-01

    Thrombotic events are a common and severe complication of endovascular aneurysm treatment with significant impact on patients' outcome. This study evaluates risk factors for thrombus formation and assesses the efficacy and safety of abciximab for clot dissolution. All patients treated with abciximab during (41 patients) or shortly after (22 patients) intracranial aneurysm coil embolisation were retrieved from the institutional database (2000 to 2007, 1,250 patients). Sixty-three patients (mean age, 55.3 years, ±12.8) had received either intra-arterial or intravenous abciximab. Risk factors for clot formation were assessed and the angiographic and clinical outcome evaluated. No aneurysm rupture occurred during or after abciximab application. The intra-procedural rate of total recanalisation was 68.3%. Thromboembolic complications were frequently found in aneurysms of the Acom complex and of the basilar artery, whilst internal carotid artery aneurysms were underrepresented. Two patients died of treatment-related intracranial haemorrhages into preexisting cerebral infarcts. Two patients developed a symptomatic groin haematoma. Abciximab is efficacious and safe for thrombolysis during and after endovascular intracranial aneurysm treatment in the absence of preexisting ischaemic stroke. (orig.)

  14. Design and application of surface coils for MR imaging with consideration of patient safety

    International Nuclear Information System (INIS)

    Bader, R.; Zabel, H.J.; Gehrig, J.; Lorenz, W.J.

    1987-01-01

    Problems concerning the safety of the patient have arisen by increasing the magnetic field for MR imaging and MR spectroscopy up to 2 T. High electric potentials result on the radio frequency (RF) that antennas in some cases are situated directly on or even inside the body. Transmit pulses can induce high voltages and currents in a separate receiver coil being resonant. Intensive RF fields emerging from the receiver coil may severely heat the conductive body tissue. Principles for suppressing the induced voltages and for detuning the antenna are described. General rules for the design of antennas and their application are discussed

  15. Analysing radio-frequency coil arrays in high-field magnetic resonance imaging by the combined field integral equation method

    Energy Technology Data Exchange (ETDEWEB)

    Wang Shumin; Duyn, Jeff H [Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Drive, 10/B1D728, Bethesda, MD 20892 (United States)

    2006-06-21

    We present the combined field integral equation (CFIE) method for analysing radio-frequency coil arrays in high-field magnetic resonance imaging (MRI). Three-dimensional models of coils and the human body were used to take into account the electromagnetic coupling. In the method of moments formulation, we applied triangular patches and the Rao-Wilton-Glisson basis functions to model arbitrarily shaped geometries. We first examined a rectangular loop coil to verify the CFIE method and also demonstrate its efficiency and accuracy. We then studied several eight-channel receive-only head coil arrays for 7.0 T SENSE functional MRI. Numerical results show that the signal dropout and the average SNR are two major concerns in SENSE coil array design. A good design should be a balance of these two factors.

  16. Switching transients in a superconducting coil

    International Nuclear Information System (INIS)

    Owen, E.W.; Shimer, D.W.

    1983-01-01

    A study is made of the transients caused by the fast dump of large superconducting coils. Theoretical analysis, computer simulation, and actual measurements are used. Theoretical analysis can only be applied to the simplest of models. In the computer simulations two models are used, one in which the coil is divided into ten segments and another in which a single coil is employed. The circuit breaker that interrupts the current to the power supply, causing a fast dump, is represented by a time and current dependent conductance. Actual measurements are limited to measurements made incidental to performance tests on the MFTF Yin-yang coils. It is found that the breaker opening time is the critical factor in determining the size and shape of the transient. Instantaneous opening of the breaker causes a lightly damped transient with large amplitude voltages to ground. Increasing the opening time causes the transient to become a monopulse of decreasing amplitude. The voltages at the external terminals are determined by the parameters of the external circuit. For fast opening times the frequency depends on the dump resistor inductance, the circuit capacitance, and the amplitude on the coil current. For slower openings the dump resistor inductance and the current determine the amplitude of the voltage to ground at the terminals. Voltages to ground are less in the interior of the coil, where transients related to the parameters of the coil itself are observed

  17. Correcting coils in end magnets of accelerators

    Directory of Open Access Journals (Sweden)

    L. R. P. Kassab

    1998-05-01

    Full Text Available We present an empirical investigation of the correcting coils behavior used to homogenize the field distribution of the race-track microtron accelerator end magnets. These end magnets belong to the second stage of the 30.0 MeV cw electron accelerator under construction at IFUSP, the race-track microtron booster, in which the beam energy is raised from 1.97 to 5.1 MeV. The correcting coils are attached to the pole faces and are based on the inhomogeneities of the magnetic field measured. The performance of these coils, when operating the end magnets with currents that differ by ±10% from the one used in the mappings that originated the coils copper leads, is presented. For one of the magnets, adjusting conveniently the current of the correcting coils makes it possible to homogenize field distributions of different intensities, once their shapes are practically identical to those that originated the coils. For the other one, the shapes are changed and the coils are less efficient. This is related to intrinsic factors that determine the inhomogeneities. However, we obtained uniformity of 0.001% in both cases.

  18. Routine phasing of coiled-coil protein crystal structures with AMPLE

    Directory of Open Access Journals (Sweden)

    Jens M. H. Thomas

    2015-03-01

    Full Text Available Coiled-coil protein folds are among the most abundant in nature. These folds consist of long wound α-helices and are architecturally simple, but paradoxically their crystallographic structures are notoriously difficult to solve with molecular-replacement techniques. The program AMPLE can solve crystal structures by molecular replacement using ab initio search models in the absence of an existent homologous protein structure. AMPLE has been benchmarked on a large and diverse test set of coiled-coil crystal structures and has been found to solve 80% of all cases. Successes included structures with chain lengths of up to 253 residues and resolutions down to 2.9 Å, considerably extending the limits on size and resolution that are typically tractable by ab initio methodologies. The structures of two macromolecular complexes, one including DNA, were also successfully solved using their coiled-coil components. It is demonstrated that both the ab initio modelling and the use of ensemble search models contribute to the success of AMPLE by comparison with phasing attempts using single structures or ideal polyalanine helices. These successes suggest that molecular replacement with AMPLE should be the method of choice for the crystallographic elucidation of a coiled-coil structure. Furthermore, AMPLE may be able to exploit the presence of a coiled coil in a complex to provide a convenient route for phasing.

  19. Transmit-Only/Receive-Only Radiofrequency System for Hyperpolarized 13C MRS Cardiac Metabolism Studies in Pigs

    DEFF Research Database (Denmark)

    Giovannetti, G.; Frijia, F.; Hartwig, V.

    2013-01-01

    Hyperpolarized 13C magnetic resonance spectroscopy in pig models enables metabolic activity mapping, providing a powerful tool for the study of the heart physiology, but requires the development of dedicated radiofrequency coils, capable of providing large field of view with high signal......-to-noise ratio (SNR) data. This work describes the simulations and the tests of a transmit-only (TX) volume coil/receive-only (RX) surface coil both designed for hyperpolarized studies of pig heart with a clinical 3T scanner. The coil characterization is performed by developing an SNR model for coil performance...

  20. Internal trim coils for CBA superconducting magnets

    International Nuclear Information System (INIS)

    Thompson, P.A.; Aronson, S.; Cottingham, J.G.; Garber, M.; Hahn, H.; Sampson, W.B.

    1983-01-01

    In order to correct iron saturation effects and shape the beam working line, superconducting trim coils have been constructed, which operate inside the main coils. Detailed studies of mechanical properties, quench behavior, fields produced, and hysteresis have lead to the production of accelerator-quality coils generating the required-strength harmonics up to cos (7theta). These are routinely installed in CBA main magnets and operate at 80% of short sample with negligible training in an ambient field of more than 5.3T

  1. Superconducting coil development and motor demonstration: Overview

    Science.gov (United States)

    Gubser, D. U.

    1995-12-01

    Superconducting bismuth-cuprate wires, coils, and magnets are being produced by industry as part of a program to test the viability of using such magnets in Naval systems. Tests of prototype magnets, coils, and wires reveal progress in commercially produced products. The larger magnets will be installed in an existing superconducting homopolar motor and operated initially at 4.2K to test the performance. It is anticipated that approximately 400 Hp will be achieved by the motor. This article reports on the initial tests of the magnets, coils, and wires as well as the development program to improve their performance.

  2. CS model coil experimental log book

    International Nuclear Information System (INIS)

    Nishijima, Gen; Sugimoto, Makoto; Nunoya, Yoshihiko; Wakabayashi, Hiroshi; Tsuji, Hiroshi

    2001-02-01

    Charging test of the ITER CS Model Coil which is the world's largest superconducting pulse coil and the CS Insert Coil had started at April 11, 2000 and had completed at August 18, 2000. In the campaign, total shot numbers were 356 and the size of the data file in the DAS (Data Acquisition System) was over 20 GB. This report is a database that consists of the log list and the log sheets of every shot. One can access the database, make a search, and browse results via Internet (http://1ogwww.naka.jaeri.go.jp). The database will be useful to quick search to choose necessary shots. (author)

  3. Large magnetic coils for fusion technology

    International Nuclear Information System (INIS)

    Komarek, P.; Ulbricht, A.

    1989-01-01

    This paper reviews the current status of research in this field and outlines future tasks and experiments for the Next European Torus (NET). Research and development work accomplished so far permits generation and safe operation of magnetic fields up to 9 T by means of NbTi coils. Fields up to 11 T are feasible if the coils are cooled with superfluid helium at 1.8 K. The potential of the Nb 3 Sn coils promise achievement of magnetic fields between 12 and 13 T. (MM) [de

  4. Using a Double-Coil TMS Protocol to Assess Preparatory Inhibition Bilaterally.

    Science.gov (United States)

    Vassiliadis, Pierre; Grandjean, Julien; Derosiere, Gerard; de Wilde, Ysaline; Quemener, Louise; Duque, Julie

    2018-01-01

    Transcranial magnetic stimulation (TMS) applied over the primary motor cortex (M1), elicits motor-evoked potentials (MEPs) in contralateral limb muscles which are valuable indicators of corticospinal excitability (CSE) at the time of stimulation. So far, most studies have used single-coil TMS over one M1, yielding MEPs in muscles of a single limb-usually the hand. However, tracking CSE in the two hands simultaneously would be useful in many contexts. We recently showed that, in the resting state, double-coil stimulation of the two M1 with a 1 ms inter-pulse interval (double-coil 1 ms TMS) elicits MEPs in both hands that are comparable to MEPs obtained using single-coil TMS. To further evaluate this new technique, we considered the MEPs elicited by double-coil 1 ms TMS in an instructed-delay choice reaction time task where a prepared response has to be withheld until an imperative signal is displayed. Single-coil TMS studies have repetitively shown that in this type of task, the motor system is transiently inhibited during the delay period, as evident from the broad suppression of MEP amplitudes. Here, we aimed at investigating whether a comparable inhibitory effect can be observed with MEPs elicited using double-coil 1 ms TMS. To do so, we compared the amplitude as well as the coefficient of variation (CV) of MEPs produced by double-coil 1 ms or single-coil TMS during action preparation. We observed that MEPs were suppressed (smaller amplitude) and often less variable (smaller CV) during the delay period compared to baseline. Importantly, these effects were equivalent whether single-coil or double-coil 1 ms TMS was used. This suggests that double-coil 1 ms TMS is a reliable tool to assess CSE, not only when subjects are at rest, but also when they are involved in a task, opening new research horizons for scientists interested in the corticospinal correlates of human behavior.

  5. Design and Fabrication of the KSTAR Poloidal Field Coil Structure

    International Nuclear Information System (INIS)

    Park, H. K.; Choi, C. H.; Sa, J. W.

    2005-01-01

    The KSTAR magnet system consists of 16 toroidal field(TF) coils. 4 pairs of central solenoid(CS) coils, and 3 pairs of outer poloidal field(PF) coils. The TF coils are encased in a structure to enhance mechanical stability. The CS coil structure is supported on top of the TF coil structure and supplies a vertical compression of 15 MN to prevent lateral movement due to a repulsive force between the CS coils. The PF coil system is vertically symmetry to the machine mid-plane and consists of 6 coils and 80 support structures(i.e, 16 for PF5, 32 for PF6 and 32 fort PF7). All PF coil structures should absorb the thermal contraction difference between TF coil structure and PF coils due to cool down and endure the vertical and radial magnetic forces due to current charging. In order to satisfy these structural requirements. the PF5 coil structure is designed base on hinges and both of PF6 and PF7 coil structures based on flexible plates. The PF coil structures are assembled on the TF coil structure with an individual basement that is welded on the TF coil structure

  6. Theory of the tensile actuation of fiber reinforced coiled muscles

    Science.gov (United States)

    Lamuta, C.; Messelot, S.; Tawfick, S.

    2018-05-01

    There is a strong need for compact artificial muscles capable of applying large contractile strokes and lift heavy weights. Coiled fibers recently emerged as attractive candidates for these purposes, owing to their simple construction and the possibility of their thermal, electrical and chemical actuation. An intuitive theoretical understanding of the mechanics of actuation of these muscles is essential for the enhancement of their performance and can pave the way for the development of new applications and technologies. In this paper, a complete theoretical model for the tensile actuation of fiber reinforced artificial muscles is presented and experimentally validated. The model demonstrates that all muscles made from the same material have a universal behavior, which can be described by a single master curve. It enables the systematic design and understanding of coiled muscles for specific performance owing to a comprehensive mathematical correlation among the geometry, materials properties, and actuation. Carbon fibers (CF)/polydimethylsiloxane coiled muscles are demonstrated as simple to fabricate yet powerful muscles owing to the availability of high strength CF. In addition to showing excellent agreement with the theoretical models, they can be actuated by joule heating or chemical swelling, lift up to 12 600 times their own weight, support up to 60 MPa of mechanical stress, provide tensile strokes higher than 25%, and a specific work up to 758 J kg‑1, the latter is more than 18 times higher than that of natural muscles.

  7. Flexible eddy current coil arrays

    International Nuclear Information System (INIS)

    Krampfner, Y.; Johnson, D.P.

    1987-01-01

    A novel approach was devised to overcome certain limitations of conventional eddy current testing. The typical single-element hand-wound probe was replaced with a two dimensional array of spirally wound probe elements deposited on a thin, flexible polyimide substrate. This provides full and reliable coverage of the test area and eliminates the need for scanning. The flexible substrate construction of the array allows the probes to conform to irregular part geometries, such as turbine blades and tubing, thereby eliminating the need for specialized probes for each geometry. Additionally, the batch manufacturing process of the array can yield highly uniform and reproducible coil geometries. The array is driven by a portable computer-based eddy current instrument, smartEDDY/sup TM/, capable of two-frequency operation, and offers a great deal of versatility and flexibility due to its software-based architecture. The array is coupled to the instrument via an 80-switch multiplexer that can be configured to address up to 1600 probes. The individual array elements may be addressed in any desired sequence, as defined by the software

  8. A fourth gradient to overcome slice dependent phase effects of voxel-sized coils in planar arrays.

    Science.gov (United States)

    Bosshard, John C; Eigenbrodt, Edwin P; McDougall, Mary P; Wright, Steven M

    2010-01-01

    The signals from an array of densely spaced long and narrow receive coils for MRI are complicated when the voxel size is of comparable dimension to the coil size. The RF coil causes a phase gradient across each voxel, which is dependent on the distance from the coil, resulting in a slice dependent shift of k-space. A fourth gradient coil has been implemented and used with the system's gradient set to create a gradient field which varies with slice. The gradients are pulsed together to impart a slice dependent phase gradient to compensate for the slice dependent phase due to the RF coils. However the non-linearity in the fourth gradient which creates the desired slice dependency also results in a through-slice phase ramp, which disturbs normal slice refocusing and leads to additional signal cancelation and reduced field of view. This paper discusses the benefits and limitations of using a fourth gradient coil to compensate for the phase due to RF coils.

  9. A coil test facility for the cryogenic tests of the JT-60SA TF coils

    International Nuclear Information System (INIS)

    Chantant, M.; Genini, L.; Bayetti, P.; Millet, F.; Wanner, M.; Massaut, V.; Corte, A. Della; Ardelier-Desage, F.; Catherine-Dumont, V.; Dael, A.; Decool, P.; Donati, A.; Duchateau, J.L.; Garibaldi, P.; Girard, S.; Hatchressian, J.C.; Fejoz, P.; Jamotton, P.; Jourdheuil, L.; Juster, F.P.

    2011-01-01

    In the framework of the Broader Approach Activities, the EU will deliver to Japan the 18 superconducting coils, which constitute the JT-60SA Toroidal field magnet. These 18 coils, manufactured by France and Italy, will be cold tested before shipping to Japan. For this purpose, the European Joint Undertaking for ITER, the Development of Fusion Energy ('Fusion for Energy', F4E) and the European Voluntary Contributors are collaborating to design and set-up a coil test facility (CTF) and to perform the acceptance test of the 18 JT-60SA Toroidal Field (TF) coils. The test facility is designed to test one coil at a time at nominal current and cryogenic temperature. The test of the first coil of each manufacturer includes a quench triggered by increasing the temperature. The project is presently in the detailed design phase.

  10. Coil measurement data acquisition and curing press control system for SSC dipole magnet coils

    International Nuclear Information System (INIS)

    Dickey, C.E.

    1989-03-01

    A coil matching program, similar in theory to the methods used to match Tevatron coils, is being developed at Fermilab. Modulus of elasticity and absolute coil size will be determined at 18-inch intervals along the coils while in the coil curing press immediately following the curing process. A data acquisition system is under construction to automatically acquire and manage the large quantities of data that result. Data files will be transferred to Fermilab's VAX Cluster for long-term storage and actual coil matching. The data acquisition system will also provide the control algorithm for the curing press hydraulic system. A description of the SSC Curing Press Data Acquisition and Controls System will be reported. 20 figs

  11. Weight-correction of carbon dioxide diffusion coefficient (DCO2 ) reduces its inter-individual variability and improves its correlation with blood carbon dioxide levels in neonates receiving high-frequency oscillatory ventilation.

    Science.gov (United States)

    Belteki, Gusztav; Lin, Benjamin; Morley, Colin J

    2017-10-01

    Carbon-dioxide elimination during high-frequency oscillatory ventilation (HFOV) is thought to be proportional to the carbon dioxide diffusion coefficient (DCO 2 ) which is calculated as frequency x (tidal volume) 2 . DCO 2 can be used to as an indicator of CO 2 elimination but values obtained in different patients cannot be directly compared. To analyze the relationship between DCO 2 , the weight-corrected DCO 2 (DCO 2 corr) and blood gas PCO 2 values obtained from infants receiving HFOV. DCO 2 data were obtained from 14 infants at 1/s sampling rate and the mean DCO 2 was determined over 10 min periods preceding the time of the blood gas. DCO 2 corr was calculated by dividing the DCO 2 by the square of the body weight in kg. Weight-correction significantly reduced the inter-individual variability of DCO 2 . When data from all the babies were combined, standard DCO 2 showed no correlation with PCO 2 but DCO 2 corr showed a weak but statistically significant inverse correlation. The correlation was better when the endotracheal leak was correlation between the HFOV tidal volume (VThf) and the PCO 2 . In any baby, DCO 2 corr >50 mL 2 /sec/kg 2 or VThf > 2.5 mL/kg was rarely needed to avoid hypercapnia. Weight-correction of DCO 2 values improved its comparability between patients. Weight-corrected DCO 2 correlated better with PCO 2 than uncorrected DCO 2 but the correlation was weak. © 2017 Wiley Periodicals, Inc.

  12. Design considerations for ITER toroidal field coils

    International Nuclear Information System (INIS)

    Kalsi, S.S.; Lousteau, D.C.; Miller, J.R.

    1987-01-01

    The International Thermonuclear Experimental Reactor (ITER) is a new tokamak design project with joint participation from Europe, Japan, the Union of Soviet Socialist Republics (U.S.S.R.), and the United States. This paper describes a magnetic and mechanical design methodology for toroidal field (TF) coils that employs Nb 3 Sn superconductor technology. Coil winding is sized by using conductor concepts developed for the U.S. TIBER concept. Manifold concepts are presented for the complete cooling system. Also included are concepts for the coil structural arrangement. The effects of in-plane and out-of-plane loads are included in the design considerations for the windings and case. Concepts are presented for reacting these loads with a minimum amount of additional structural material. Concepts discussed in this paper could be considered for the ITER TF coils

  13. 12 tesla test coil. Annual progress report

    International Nuclear Information System (INIS)

    1979-01-01

    The Plasma Fusion Center at MIT has been charged with responsibility for the design, development, fabrication and test operation of a Niobium-3-Tin Superconducting Test Coil. Research is described on DOE's 12 tesla coil demonstration program in which several one-meter diameter superconducting test coils will be inserted and tested in DOE's High Field Test Facility at the Lawrence Livermore Laboratories. The work was initiated at the start of FY 79. FY 79 saw the completion of our Preliminary Design and the initiation of three (3) subcontracts: (1) Westinghouse review of the Preliminary Design, (II) Supercon, Inc. development of a tubular copper matrix, Nb 3 Sn Superconductor and (III) Airco optimization of the LCP-W Nb 3 Sn superconductor for 12T service. In addition, Airco was charged with the production of a 1000 foot length of model 15,000A conductor. Coil winding exercises were initiated at the Everson Electric Company

  14. OCLATOR (One Coil Low Aspect Toroidal Reactor)

    Energy Technology Data Exchange (ETDEWEB)

    Yoshikawa, S.

    1980-02-01

    A new approach to construct a tokamak-type reactor(s) is presented. Basically the return conductors of toroidal field coils are eliminated and the toroidal field coil is replaced by one single large coil, around which there will be placed several tokamaks or other toroidal devices. The elimination of return conductors should, in addition to other advantages, improve the accessibility and maintainability of the tokamaks and offer a possible alternative to the search for special materials to withstand large neutron wall loading, as the frequency of changeover would be increased due to minimum downtime. It also makes it possible to have a low aspect ratio tokamak which should improve the ..beta.. limit, so that a low toroidal magnetic field strength might be acceptable, meaning that the NbTi superconducting wire could be used. This system is named OCLATOR (One Coil Low Aspect Toroidal Reactor).

  15. Advanced Singlet Oxygen Generator for a COIL

    National Research Council Canada - National Science Library

    Kodymova, Jarmila; Zagidullin, M; Nikolaev, V; Svistun, M; Khvatov, N; Hruby, J; Spalek, O; Jirasek, V; Censsky, M

    2005-01-01

    This report results from a contract tasking Academy of Sciences as follows: The Grantee will develop new and radically different ideas for a high performance, advanced singlet oxygen generator for driving a supersonic COIL...

  16. Helium leak testing the Westinghouse LCP coil

    International Nuclear Information System (INIS)

    Merritt, P.A.; Attaar, M.H.; Hordubay, T.D.

    1983-01-01

    The tests, equipment, and techniques used to check the Westinghouse LCP coil for coolant flow path integrity and helium leakage are unique in terms of test sensitivity and application. This paper will discuss the various types of helium leak testing done on the LCP coil as it enters different stages of manufacture. The emphasis will be on the degree of test sensitivity achieved under shop conditions, and what equipment, techniques and tooling are required to achieve this sensitivity (5.9 x 10 -8 scc/sec). Other topics that will be discussed are helium flow and pressure drop testing which is used to detect any restrictions in the flow paths, and the LCP final acceptance test which is the final leak test performed on the coil prior to its being sent for testing. The overall allowable leak rate for this coil is 5 x 10 -6 scc/sec. A general evaluation of helium leak testing experience are included

  17. Radiative MRI Coil Design Using Parasitic Scatterers

    DEFF Research Database (Denmark)

    Sanchez-Heredia, Juan D.; Avendal, Johan; Bibic, Adnan

    2018-01-01

    allows for antenna design techniques to be adapted to RF coil designs. This study proposes the use of parasitic scatterers to improve the performance of an existing 7T MRI coil called the single-sided adapted dipole (SSAD) antenna. The results reveal that scatterers arranged in a Yagi fashion can......Conventionally, radiofrequency (RF) coils used for magnetic resonance imaging (MRI) are electrically small and designed for nearfield operation. Therefore, existing antenna design techniques are mostly irrelevant for RF coils. However, the use of higher frequencies in ultrahigh field (UHF) MRI...... be applied to reduce local specific absorption rate (SAR) maxima of a reference SSAD by 40% with only a 6% decrease in the propagated B1 + field at the tissue depth of 15 cm. The higher directivity of the proposed design also decreasing the coupling with additional elements, making this antenna...

  18. MR angiography after coiling of intracranial aneurysms

    NARCIS (Netherlands)

    Schaafsma, J.D.

    2012-01-01

    Introduction Endovascular occlusion with detachable coils has become an alternative treatment to neurosurgical clipping of intracranial aneurysms over the last two decades. Its minimal invasiveness is the most important advantage of this treatment compared to clipping. The disadvantage of occlusion

  19. Novel Anti-Nicotine Vaccine Using a Trimeric Coiled-Coil Hapten Carrier.

    Directory of Open Access Journals (Sweden)

    Keith D Miller

    Full Text Available Tobacco addiction represents one of the largest public health problems in the world and is the leading cause of cancer and heart disease, resulting in millions of deaths a year. Vaccines for smoking cessation have shown considerable promise in preclinical models, although functional antibody responses induced in humans are only modestly effective in preventing nicotine entry into the brain. The challenge in generating serum antibodies with a large nicotine binding capacity is made difficult by the fact that this drug is non-immunogenic and must be conjugated as a hapten to a protein carrier. To circumvent the limitations of traditional carriers like keyhole limpet hemocyanin (KLH, we have synthesized a short trimeric coiled-coil peptide (TCC that creates a series of B and T cell epitopes with uniform stoichiometry and high density. Here we compared the relative activities of a TCC-nic vaccine and two control KLH-nic vaccines using Alum as an adjuvant or GLA-SE, which contains a synthetic TLR4 agonist formulated in a stable oil-in-water emulsion. The results showed that the TCC's high hapten density correlated with a better immune response in mice as measured by anti-nicotine Ab titer, affinity, and specificity, and was responsible for a reduction in anti-carrier immunogenicity. The Ab responses achieved with this synthetic vaccine resulted in a nicotine binding capacity in serum that could prevent >90% of a nicotine dose equivalent to three smoked cigarettes (0.05 mg/kg from reaching the brain.

  20. Boiling heat transfer and dryout in helically coiled tubes under different pressure conditions

    International Nuclear Information System (INIS)

    Chung, Young-Jong; Bae, Kyoo-Hwan; Kim, Keung Koo; Lee, Won-Jae

    2014-01-01

    Highlights: • Heat transfer characteristics and dryout for helically coiled tube are performed. • A boiling heat transfer tends to increase with a pressure increase. • Dryout occurs at high quality test conditions investigated. • Steiner–Taborek’s correlation is predicted well based on the experimental results. - Abstract: A helically coiled once-through steam generator has been used widely during the past several decades for small nuclear power reactors. The heat transfer characteristics and dryout conditions are important to optimal design a helically coiled steam generator. Various experiments with the helically coiled tubes are performed to investigate the heat transfer characteristics and occurrence condition of a dryout. For the investigated experimental conditions, Steiner–Taborek’s correlation is predicted reasonably based on the experimental results. The pressure effect is important for the boiling heat transfer correlation. A boiling heat transfer tends to increase with a pressure increase. However, it is not affected by the pressure change at a low power and low mass flow rate. Dryout occurs at high quality test conditions investigated because a liquid film on the wall exists owing to a centrifugal force of the helical coil

  1. Magnetic Test Facility - Sensor and Coil Calibrations

    Science.gov (United States)

    2013-08-01

    amplitude of signals induced into the sensor. 2.1.1.2 Fluxgate magnetometers Fluxgate sensors consist of a ferromagnetic core, around which drive and sense...kHz range to be measured. Fluxgate magnetometers do not have a lower limit to their fre- quency response, and hence can be used to measure...placed within a larger triaxial coil which is used in conjunction with a fluxgate magnetometer to cancel earth’s field at the cen- tre of the coil. A

  2. Quadruple Cone Coil with improved focality than Figure-8 coil in Transcranial Magnetic Stimulation

    Science.gov (United States)

    Rastogi, Priyam; Lee, Erik G.; Hadimani, Ravi L.; Jiles, David C.

    Transcranial Magnetic Stimulation (TMS) is a non-invasive therapy which uses a time varying magnetic field to induce an electric field in the brain and to cause neuron depolarization. Magnetic coils play an important role in the TMS therapy since their coil geometry determines the focality and penetration's depth of the induced electric field in the brain. Quadruple Cone Coil (QCC) is a novel coil with an improved focality when compared to commercial Figure-8 coil. The results of this newly designed QCC coil are compared with the Figure-8 coil at two different positions of the head - vertex and dorsolateral prefrontal cortex, over the 50 anatomically realistic MRI derived head models. Parameters such as volume of stimulation, maximum electric, area of stimulation and location of maximum electric field are determined with the help of computer modelling of both coils. There is a decrease in volume of brain stimulated by 11.6 % and a modest improvement of 8 % in the location of maximum electric field due to QCC in comparison to the Figure-8 coil. The Carver Charitable Trust and The Galloway Foundation.

  3. Magnetic resonance dacryocystography: comparison between conventional surface coils and microscopic coils

    International Nuclear Information System (INIS)

    Abreu Junior, Luiz de; Wolosker, Angela Maria Borri; Borri, Maria Lucia; Galvao Filho, Mario de Melo; Hartmann, Luiz Guilherme de Carvalho; D'Ippolito, Giuseppe; Castro, Claudio Campi de

    2008-01-01

    Objective: Magnetic resonance imaging has been utilized in the evaluation of the lacrimal apparatus with some advantages over conventional dacryocystography. The present study was aimed at acquiring high resolution images utilizing microscopic coils for evaluating typical structures of the lacrimal apparatus as compared with the findings observed with conventional surface coils. Materials and methods: Five asymptomatic volunteers with no history of epiphora were submitted to high-field magnetic resonance imaging with microscopic and conventional surface coils, and STIR sequence after instillation of saline solution. The definition of normal anatomic structures of lacrimal apparatuses was compared utilizing conventional and microscopic surface coils. Based on a consensual scoring system, the mean values for each structure were calculated by two observers. Results: In 90% of cases, higher scores were attributed to images acquired with the microscopic coil. On average, a 1.17 point increase was observed in the scoring of anatomic structures imaged with the microscopic coil. Additionally, a subjective improvement was observed in the signal-to-noise ratio with the microscopic coil. Conclusion: Magnetic resonance dacryocystography with microscopic coils is the appropriate method for evaluating the lacrimal apparatus, providing images with better quality as compared with those acquired with conventional surface coils. (author)

  4. An analysis of 3D solvation structure in biomolecules: application to coiled coil serine and bacteriorhodopsin.

    Science.gov (United States)

    Hirano, Kenji; Yokogawa, Daisuke; Sato, Hirofumi; Sakaki, Shigeyoshi

    2010-06-17

    Three-dimensional (3D) solvation structure around coiled coil serine (Coil-Ser) and inner 3D hydration structure in bacteriorhodopsin (bR) were studied using a recently developed method named multicenter molecular Ornstein-Zernike equation (MC-MOZ) theory. In addition, a procedure for analyzing the 3D solvent distribution was proposed. The method enables us to calculate the coordination number of solvent water as well as the strength of hydrogen bonding between the water molecule and the protein. The results for Coil-Ser and bR showed very good agreement with the experimental observations.

  5. Thomson's Jumping Ring over a Long Coil

    Science.gov (United States)

    Jeffery, Rondo N.; Amiri, Farhang

    2018-01-01

    The classic jumping ring apparatus consists of a coil with an iron core that extends out of the coil. A copper or aluminum ring placed over the iron core jumps upward when AC power is applied to the coil. In this paper we will examine a modified design of the jumping ring apparatus, called the "long-coil design." It allows the ring to…

  6. COMPASS magnetic field coils and structure systems

    International Nuclear Information System (INIS)

    Crossland, R.T.; Booth, J.A.; Hayward, R.J.; Keogh, P.; Pratt, A.P.

    1987-01-01

    COMPASS is a new experimental toroidal assembly of compact design and with a wide range of physics objectives. It is required to operate either as a Tokamak or as a Reversed Field Pinch with interchangeable circular and dee-section vacuum vessels. The Toroidal field is produced by 16 rectangular coils of 4 turns with tapered conductors on the inside which nest together to form a vault to resist the centering forces. The coils are designed to produce a maximum field on axis of 2.1T which requires a current of 91 kA per turn. Two central solenoids and five pairs of coils symmetrically positioned above and below the machine equator provide the poloidal field. Both coil systems are supported form a mechanical support structure which surrounds the machine. This is primarily designed to resist out-of-plane forces on the TF coils but also acts as the base support for the PF coils and vacuum vessels. An illustration of the COMPASS Load Assembly is given and shows the D-shaped vacuum vessel, the major components and the various field windings

  7. Embroidered Coils for Magnetic Resonance Sensors

    Directory of Open Access Journals (Sweden)

    Michael I. Newton

    2013-04-01

    Full Text Available Magnetic resonance imaging is a widely used technique for medical and materials imaging. Even though the objects being imaged are often irregularly shaped, suitable coils permitting the measurement of the radio-frequency signal in these systems are usually made of solid copper. One problem often encountered is how to ensure the coils are both in close proximity and conformal to the object being imaged. Whilst embroidered conductive threads have previously been used as antennae in mobile telecommunications applications, they have not previously been reported for use within magnetic resonance. In this paper we show that an embroidered single loop coil can be used in a commercial unilateral nuclear magnetic resonance system as an alternative to a solid copper. Data is presented showing the determination of both longitudinal (T1 and effective transverse (T2eff relaxation times for a flat fabric coil and the same coil conformed to an 8 cm diameter cylinder. We thereby demonstrate the principles required for the wider use of fabric based conformal coils within nuclear magnetic resonance and magnetic resonance imaging.

  8. Dual levitated coils for antihydrogen production

    Science.gov (United States)

    Wofford, J. D.; Ordonez, C. A.

    2013-04-01

    Two coaxial superconducting magnetic coils that carry currents in the same direction and that are simultaneously levitated may serve for antihydrogen plasma confinement. The configuration may be suitable for use by a collaboration at the CERN Antiproton Decelerator facility to test fundamental symmetries between the properties of hydrogen and antihydrogen. Nested Penning traps are currently used to confine recombining antihydrogen plasma. Symmetry studies require the production of sufficiently cold antihydrogen. However, plasma drifts within nested Penning traps can increase the kinetic energy of antiprotons that form antihydrogen atoms. Dual levitated coils may serve to confine relatively large, cold, dense non-drifting recombining antihydrogen plasmas. A minimum-B magnetic field that is produced by the coils could provide for atom trapping. A toroidal plasma is confined between the coils. High density plasmas may be possible, by allowing plasma pressure to balance mechanical pressure to keep the coils apart. Progress is reported on theoretical and experimental efforts. The theoretical effort includes the development of a classical trajectory Monte Carlo simulation of confinement. The experimental effort includes levitation of a NdFeB permanent ring magnet, which produces a magnetic field that is qualitatively similar to the field that would be produced by the two coaxial superconducting magnetic coils. Liquid-nitrogen-cooled Bi-2223 high-temperature-superconducting components, with a critical temperature of 108 K, were used to levitate the ring magnet. An issue concerning keeping the plane of the levitated ring horizontal is discussed.

  9. [Surface coils for magnetic-resonance images].

    Science.gov (United States)

    Rodríguez-González, Alfredo Odón; Amador-Baheza, Ricardo; Rojas-Jasso, Rafael; Barrios-Alvarez, Fernando Alejandro

    2005-01-01

    Since the introduction of magnetic resonance imaging in Mexico, the development of this important medical imaging technology has been almost non-existing in our country. The very first surface coil prototypes for clinical applications in magnetic resonance imaging has been developed at the Center of Research in Medical Imaging and Instrumentation of the Universidad Autónoma Metropolitana Iztapalapa (Metropolitan Autonomous University, Campus Iztapalapa). Two surface coil prototypes were built: a) a circular-shaped coil and b) a square-shaped coil for multiple regions of the body, such as heart, brain, knee, hands, and ankles. These coils were tested on the 1.5T imager of the ABC Hospital-Tacubaya, located in Mexico City. Brain images of healthy volunteers were obtained in different orientations: sagittal, coronal, and axial. Since images showed a good-enough clinical quality for diagnosis, it is fair to say that these coil prototypes can be used in the clinical environment, and with small modifications, they can be made compatible with almost any commercial scanner. This type of development can offer new alternatives for further collaboration between the research centers and the radiology community, in the search of new applications and developments of this imaging technique.

  10. 16-Channel surface coil for 13C-hyperpolarized spectroscopic imaging of cardiac metabolism in pig heart

    DEFF Research Database (Denmark)

    Frijia, Francesca; Santarelli, Maria Filomena; Koellisch, Ulrich

    2016-01-01

    Magnetic resonance spectroscopy (MRS) of hyperpolarized 13C pyruvate and its metabolites in large animal models is a powerful tool for assessing cardiac metabolism in patho-physiological conditions. In 13C studies, a high signal-to-noise ratio (SNR) is crucial to overcome the intrinsic data quality...... both targets. In this study, a 16-channel receive surface coil was designed for 13C hyperpolarized studies of the pig heart with a clinical 3-T scanner. The coil performance was characterized by phantom experiments and compared with that of a birdcage coil used in transmit/receive mode. Segmental...... of the 16-channel coil is recommended for studies of septal and anterior LV walls....

  11. Middle and long-term follow-up of intracranial aneurysms treated with Matrix detachable coils

    International Nuclear Information System (INIS)

    Wu Xi; Liu Jianmin; Huang Qinghai; Xu Yi

    2008-01-01

    Objective: This study was undertaken to evaluate the safety of the polyglycolic/polylactic acid (PGLA)-coated Matrix detachable coils (Matrix) and analyze factors which may relate to the recanalization rate of the Matrix coils in the treatment of intracranial aneurysms. Methods: 75 patients underwent 79 aneurysm treatments with Matrix coils from May 2003 to July 2005 were retrospectively investigated. Morphological changes were compared postoperatively with last-follow-up digital subtraction angiography (DSA) by using the Raymond scale. We defined incomplete recanalization or stable aneurysms as uncured, while those of progressive occlusion or complete occlusion aneurysms demonstrated on the last-follow-up imagings as cured. We also utilized Cox model for analyzing the relationships between factors including age, gender, degree of aneurysmal occlusion, stenting, aneurysm neck size, aneurysm maximum size and Matrix coils length (%) and the long-term angiographic follow-up results. Results: The correlative surgical complications rate with Matrix coils was 13.3%. The total rate of recanalization was 11.4%. Large aneurysms treated with combined stenting got 40% recanalization. No statistic relationships were shown between the factors forementioned and the recanalization rate, but progressive occlusion was observed in 11 (61%)incompletely treated aneurysms. Conclusions: Matrix detachable coil technique is safe for intracranial aneurysm and would further decrease the recurrence of large aneurysm with combination of stenting but long term efficacy needs further follow-up and large scale randomized control study. (authors)

  12. Superior MR images with electronically tuned and decoupled surface coils

    International Nuclear Information System (INIS)

    Ingwersen, H.; Freisen, L.; Friedrich, A.; Kess, H.; Krause, N.; Meissner, R.; Popp, W.

    1987-01-01

    In order to gain free positioning of surface coils in linearly polarized transmitting coils, it is absolutely necessary to electronically decouple both coils. For circularly polarized transmitting coils, decoupling is necessary in any case. In addition to the decoupling circuit automatic electronic tuning of the surface coils is used to gain the bast ratio of signal to noise. This combination of electronically decoupling and tuning of the surface coils yields intrinsic patient safety concerning local power deposition as well as free positioning and easy handling at the same time. Block diagrams, circuit schemes, and MR images obtained with several different surface coils are shown

  13. STRUCTURAL RESPONSE OF THE DIII-D TOROIDAL FIELD COIL TO INCREASED LATERAL LOADS

    International Nuclear Information System (INIS)

    REIS, E.E; CHIN, E.

    2004-03-01

    OAK-B135 Recent calibration shots in which full toroidal field (TF) coil current interacted with the maximum poloidal field coils have produced increased lateral loads on the outer sections of the TF-coil. The increased lateral loads have resulted in deflections that have been sufficient to cause the TF-coil to contact adjacent equipment and produce a transient short to ground within the coil. The six outer turns of each TF-coil bundle are clamped together by insulated preloaded studs to provide increased bending stiffness. These sections of the outer bundles depend on friction to react the lateral loads as a bundle rather than six individual turns. A major concern is that the increased loads will produce slip between turns resulting in excessive lateral deflections and possible damage to the insulating sleeve on the preloaded studs. A finite element structural model of the TF-coil was developed for the calculation of deflections and the shear load distribution throughout the coil for the applied lateral loads from a full current calibration shot. The purpose of the updated structural model is to correlate the applied lateral loads to the total shear force between the unbonded sections of the outer turns. An allowable integrated lateral load applied to the outer turns is established based on the maximum shear force that can be reacted by friction. A program that calculates the magnetic fields and integrated lateral load along the outer turns can be incorporated into the plasma control system. The integrated load can then be compared to the calculated allowable value prior to execution of calibration shots. Calibration shots with a calculated total lateral load greater than the allowable value will be prevented

  14. Experimental approach to investigate the constrained recovery behavior of coiled monofilament polymer fibers

    Science.gov (United States)

    Mendes, S. S.; Nunes, L. C. S.

    2017-11-01

    The aim of this work is to propose a new approach for investigating the thermo-mechanical behavior of coiled oriented polymer fibers with fixed ends and promote an understanding of the actuation response of coiled polymers in constrained recovery applications. In the proposed experimental methodology, a coiled fiber was pre-stretched by 50% and the distance between its ends remained constant, then it was subjected to a heating-cooling cycle ranging from 30 °C to 120 °C and the induced restoring force was measured. Based on these measurements, axial deformation and shear strain were obtained from full-field displacements extracted by the digital image correlation method from images of the coiled fiber. Three coiled fibers with different initial pitch angles were manufactured, and samples with lengths of 15 mm and 20 mm were tested. Bias angles and coil radius were also estimated using the experimental data associated with the helical spring theory. Results show that significant shape changes can be noticed above the glass transition temperature (47 °C), and these changes induce variation in the resultant forces. The effects of thermal softening and thermal contraction for a modest negative thermal expansion coefficient became evident at temperatures ranging from ∼47 °C to ∼90 °C, while the response of a coiled homochiral polymer fiber was achieved at temperatures close to 90 °C. During the cooling process, saturated states of the axial deformation and shear strain of the coiled fibers were observed at temperatures between 120 °C and 100 °C.

  15. Coil supporting device in a nuclear fusion device

    International Nuclear Information System (INIS)

    Takano, Hirohisa; Sasaki, Katsutoki.

    1976-01-01

    Object: To slide a vacuum vessel in the nuclear fusion device and a coil within the vacuum vessel and to mount the coil within the vacuum vessel in a manner that it may not be moved by an electromagnetic force, thereby preventing stress from being produced in the coil. Structure: A coil supporting plate mounted at upper and lower parts prevents damage to an insulation of the coil, said coil being held in a U-shaped groove, and can be moved integral with the coil by the action of a roller bearing with a plurality of needle-like rollers arranged in parallel. The coil supporting plate has a plurality of projections disposed on the lower surface thereof, and flat springs are placed in the projections one over another so that the spring action exerted in the lower plate causes the coil to be resiliently bias in a direction of an electromagnetic force applied thereto and to support the coil. (Yoshino, Y.)

  16. HydroSoft coil versus HydroCoil for endovascular aneurysm occlusion study: A single center experience

    International Nuclear Information System (INIS)

    Guo Xinbin; Fan Yimu; Zhang Jianning

    2011-01-01

    Background and purpose: The HydroCoil Embolic System (HES) was developed to reduce recurrences of aneurysms relative to platinum coils. But the HydroCoil Embolic System was characterized with many limitations. The manufacturer had recognized the challenge and recently a new design of hydrogel-coated coil-HydroSoft has become available in the market as the new generation HydroCoil. We reported our initial experience using HydroSoft coil versus HydroCoil in our center. Methods: 75 aneurysms embolized primarily using HydroSoft Coils from July 2008 to May 2009 were compared with 66 volume- and shape-matched aneurysms treated with HydroCoils from March 2006 to August 2008. Outcome measures included length and number of coils used, contrast volume, and length of hospital stay. During embolization, a stable framework was first established with bare coils, and hydrogel-coated coils were used subsequently to increase the packing density. Follow-up angiographic results 6 months after treatment were evaluated among some of the patients. Results: Successful coil embolization was achieved in all patients. There were no differences in average total coil length used per aneurysm. There were no differences in length of hospital stay and packing density. HydroSoft coils were more suitable using as the finishing or final coil. HydroSoft coil decreased the procedure-related retreated rates, and aneurysm packing was finished with soft, flexible HydroSoft coil and decreased the neck remnant rates. Follow-up angiography in HydroSoft-treated patients at 6 months revealed aneurysm stability without significant residual neck. Conclusions: HydroSoft coil allowed us to deploy coated coils with good packing density. A slight expansion of these coils at the neck can be expected to reduce neck remnant and potentially inhibit recurrence.

  17. Versatile fill coils: initial experience as framing coils for oblong aneurysms. A technical case report.

    Science.gov (United States)

    Osanai, Toshiya; Bain, Mark; Hui, Ferdinand K

    2014-01-01

    Coil embolization of oblong aneurysms is difficult because the majority of commercially available coils are manufactured with a helical or spherical tertiary structure. While adopting framing strategies for oblong aneurysms (aspect ratio ≥ 2: 1), traditional coils may be undersized in the long axis but oversized in the short axis, resulting in increased aneurysmal wall stress, risk of re-rupture, and difficulty creating a basket that respects the aneurysmal neck. We review three cases in which versatile filling coils (VFCs) were used as the initial coils for embolization of oblong aneurysms and report coil distribution characteristics and clinical outcomes. Packing density after VFC implantation was assessed using the software AngioSuite-Neuro edition and AngioCalc. a 58-year-old woman experienced a subarachnoid hemorrhage from a ruptured anterior communicating artery aneurysm (7.5 mm × 3.5 mm). A 3-6 mm × 15 cm VFC was selected as the first coil because the flexibility of its wave-loop structure facilitates framing of an irregularly shaped aneurysm. The loop portions of the structures tend to be pressed to the extremes of the aneurysmal sac by the wave component. The VFC was introduced smoothly into the aneurysmal sac without catheter kickback. We were then able to insert detachable filling coils without any adjunctive technique and achieved complete occlusion. Complete occlusion without severe complications was achieved in all three cases in our study. Average packing density after the first coil was 15.63%. VFC coils may have a specific role in framing oblong aneurysms given their complex loop-wave design, allowing spacing of the coils at the dome and neck while keeping sac stress to a minimum.

  18. Surgical management of an ACM aneurysm eight years after coiling.

    Science.gov (United States)

    Pogády, P; Fellner, F; Trenkler, J; Wurm, G

    2007-04-01

    The authors present a case report on rebleeding of a medial cerebral aneurysm (MCA) eight years after complete endovascular coiling. The primarily successfully coiled MCA aneurysm showed a local regrowth which, however, was not the source of the rebleeding. The angiogram demonstrated no evidence of contrast filling of the coiled segment, but according to intraoperative findings (haematoma location, displacement of coils, evident place of rupture) there is no doubt that the coiled segment of the aneurysm was responsible for the haemorrhage.

  19. Modelling Wireless Power Transfer Using an Array of Tesla Coils

    Science.gov (United States)

    Pierson, Casey Thomas

    Wireless power transmission, or WPT, is a well-demonstrated property in electrical science and physics. Coil-and-wave transmission (CWT) consists of two Tesla coils, one powered by a controlled voltage source v src and one connected across a generic load Z 0 , at a mid- to long range distance apart with spherical capacitors at each of their top loads. The literature on the different methods of WPT varies widely, but research of CWT is sparse, lacking especially in the area of computer simulation. Recently, a physical experiment was conducted by Marzolf et al. in [1], and yielded surprising resonant frequencies in the high frequency range. The goal of this research is to answer the question of whether these reosnant frequencies originate in unexplained field effects or in non-ideal circuit behavior, and establish a formal model to indicate at what frequencies the resonant peaks occur as a first approximation. By carefully constructing a simulation of the most geometrically simple, power efficient design in the work of Marzolf et al. using the scientific software Octave, we investigate these frequencies computationally: first, an ideal scenario that has no flux leakage or exterior losses is modelled mathematically and simulated, and then, a non-ideal scenario that accounts for losses in the coils and surroundings is modelled mathematically and simulated. Both models utilize a simple formula for spherical capacitance for the top loads. After running these simulations through detailed sampling up to 4 MHz, the ideal model could not account for the resonant peaks, while the non-ideal model indicated the resonant peaks near the exact frequency ranges that were observed. An unexpected characteristic of these results was that coupling coefficients between the coils of the transmitter and receiver played a noticeable part in the indication of resonant peaks. This demonstrates that unknown field effects are not the primary driver of resonance in the ideal or non

  20. The role of endorectal coil MRI in patient selection and treatment planning for prostate seed implants

    International Nuclear Information System (INIS)

    Clarke, Daniel H.; Banks, Stephen J.; Wiederhorn, A. Roger; Klousia, John W.; Lissy, Jeanne M.; Miller, Michelle; Able, Arnold M.; Artiles, Carlos; Hindle, William V.; Blair, Deborah N.; Houk, Russell R.; Sheridan, Michael J.

    2002-01-01

    Purpose: To assess the role of endorectal coil magnetic resonance imaging (MRI) staging for patients undergoing seed implantation (SI) with or without external beam radiotherapy (EBRT). Methods and Materials: Between October 1994 and December 1998, 390 patients underwent prostate SI (98% Pd-103, 2% I-125). Seventy-six percent of patients had a prostate serum antigen (PSA) 20. Ten percent of patients had a Gleason score (GS) of 4-5, 54% had GS 6, 29% had GS 7, and 7% had GS ≥ 8. Monotherapy was employed in 46% of patients, and the remaining 54% received combined EBRT and SI. Three hundred twenty-seven were staged by high-resolution phased array pelvic coil, or in most cases, an endorectal coil MRI. The MRI findings were used to guide stage-appropriate treatment recommendations, and to assist in the preplanning and optimization of seed distributions. The criteria utilized to determine MRI-based stage were founded on the reported literature from the University of Pennsylvania. All MRI studies were reviewed by C.A., D.B., or W.H., who were unaware of clinical stage at the time of their review. The biopsy report was available to them as the only clinical correlate. Results: Of the 327 patients staged by MRI, 70% were upstaged from the digital rectal examination-based clinical stage; 26% of T 1 , T 2 patients were upstaged to T 3 . Perineural invasion and the percentage of positive cores predicted for T 3 MRI stage (p 3 intermediate-risk group patients treated by combined therapy with a previous study of T 3 intermediate-risk group treated by radical prostatectomy (RP) at the University of Pennsylvania. Our 36-month PSA FFP was 94% compared with 21% for the previous study's RP patients. Conclusion: MRI is a valuable staging procedure for prostate cancer patients treated by SI. PSA FFP results appear to be improved by MRI staging. MRI T 3 disease can be treated more effectively by SI + EBRT than by RP

  1. Gradient coil system for nuclear magnetic resonance apparatus

    International Nuclear Information System (INIS)

    Frese, G.; Siebold, H.

    1984-01-01

    A gradient coil system for an image-generating, nuclear magnetic resonance tomographic apparatus, particularly a zeugmatographic apparatus. The gradient coil system is arranged on a support body of rotational symmetry, illustratively a hollow cylindrical support body, having an axis which extends along the z-direction of an x, y, z coordinate system which has an origin in the center of imaging region. The gradient coil system contains two pairs of toroidal individual coils which are arranged symmetrically with respect to an x-y plane which extends through the center of the imaging region and which are arranged perpendicular to the z-axis. The direction of current flow in the individual coils of a coil pair is opposite to the direction of flow in the individual coils of the other coil pair. Moreover, further sets of coils are provided for generating field gradient Gx in the x-direction, and Gy in the y-direction. The hollow cylindrical shape of the support body on which the individual coils are arranged permit an imaging region having a substantially spherical volume with a substantially constant field gradient Gz to be achieved. Each of the coils has a predetermined linkage factor which corresponds to the product of the current flowing through the number of coil turns of the coil. Those coils which are arranged further from the plane of symmetry have a substantially larger linkage factor than the coils which are nearer to the plane of symmetry

  2. Comparison of surface coil and knee coil for evaluation of the patellar cartilage by MR imaging

    International Nuclear Information System (INIS)

    Steen, M. van den; Maeseneer, M. de; Hoste, M.; Vanderdood, K.; Ridder, F. de; Osteaux, M.

    2003-01-01

    Purpose: The aim of this work was to compare the knee coil and the surface coil for the visualisation of the patellar cartilage. Materials and methods: In 28 patients (17 women, 11 men) with an average age of 40 years (range 14-76) with knee pain MR was performed. Transverse images were obtained using a fast spin echo proton density weighted sequence on a Philips Gyroscan Intera 1.5 T clinical system. Transverse images were obtained at the level of the patellar cartilage using both the surface and the knee coil. All images were evaluated by consensus of two radiologists. They evaluated a number of quality criteria on a 4-point scale. Criteria for artefacts were also graded on a 4-point scale. Results: For the visualisation of fluid there was no significant difference between the knee coil and the surface coil (P=0.021). For all other criteria regarding image quality and presence of imaging artefacts there was a significant difference between both coils (P<0.001) with the surface coil obtaining the better result. Conclusion: The use of the surface coil in the visualisation of the patellar cartilage can be recommended at knee MR

  3. Immunogenicity of coiled-coil based drug-free macromolecular therapeutics

    Czech Academy of Sciences Publication Activity Database

    Kverka, Miloslav; Hartley, J.M.; Chu, T.W.; Yang, J.; Heidchen, R.; Kopeček, J.

    2014-01-01

    Roč. 35, č. 2 (2014), s. 5886-5896 ISSN 1616-0177 R&D Projects: GA MŠk(CZ) EE2.3.30.0003 Grant - others:NIH(US) GM095606 Institutional support: RVO:61388971 Keywords : coiled-coil * enantiomers * HPMA copolymer Subject RIV: EC - Immunology

  4. Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins

    NARCIS (Netherlands)

    Sinka, Rita; Gillingham, Alison K.; Kondylis, Vangelis; Munro, Sean

    2008-01-01

    Vesicles and other carriers destined for the Golgi apparatus must be guided to the correct cisternae. Golgins, long coiled-coil proteins that localize to particular Golgi subdomains via their C termini, are candidate regulators of vesicle sorting. In this study, we report that the GRIP domain

  5. Anisotropic metamaterial for efficiency enhancement of mid-range wireless power transfer under coil misalignment

    International Nuclear Information System (INIS)

    Ranaweera, A L A K; Moscoso, Carlos Arriola; Lee, Jong-Wook

    2015-01-01

    In a wireless power transfer (WPT) system, misalignment between transmitter and receiver coils is one of the key factors affecting efficiency. Recently, metamaterials have shown great potential to enhance electromagnetic propagation in various environments. In this work, we apply a metamaterial to enhance the WPT in a more general environment where misalignment is considered. Using an anisotropic metamaterial, we obtain a significant efficiency enhancement. Therefore, we propose that the metamaterial is an effective means to mitigate the decreased efficiency caused by misalignment. In addition, we investigate the effect of coil misalignment on the threshold distance beyond which the metamaterial enhances the performance of WPT. (paper)

  6. Textural features in pre-treatment [F18]-FDG-PET/CT are correlated with risk of local recurrence and disease-specific survival in early stage NSCLC patients receiving primary stereotactic radiation therapy.

    Science.gov (United States)

    Pyka, Thomas; Bundschuh, Ralph A; Andratschke, Nicolaus; Mayer, Benedikt; Specht, Hanno M; Papp, Laszló; Zsótér, Norbert; Essler, Markus

    2015-04-22

    Textural features in FDG-PET have been shown to provide prognostic information in a variety of tumor entities. Here we evaluate their predictive value for recurrence and prognosis in NSCLC patients receiving primary stereotactic radiation therapy (SBRT). 45 patients with early stage NSCLC (T1 or T2 tumor, no lymph node or distant metastases) were included in this retrospective study and followed over a median of 21.4 months (range 3.1-71.1). All patients were considered non-operable due to concomitant disease and referred to SBRT as the primary treatment modality. Pre-treatment FDG-PET/CT scans were obtained from all patients. SUV and volume-based analysis as well as extraction of textural features based on neighborhood gray-tone difference matrices (NGTDM) and gray-level co-occurence matrices (GLCM) were performed using InterView Fusion™ (Mediso Inc., Budapest). The ability to predict local recurrence (LR), lymph node (LN) and distant metastases (DM) was measured using the receiver operating characteristic (ROC). Univariate and multivariate analysis of overall and disease-specific survival were executed. 7 out of 45 patients (16%) experienced LR, 11 (24%) LN and 11 (24%) DM. ROC revealed a significant correlation of several textural parameters with LR with an AUC value for entropy of 0.872. While there was also a significant correlation of LR with tumor size in the overall cohort, only texture was predictive when examining T1 (tumor diameter 3 cm) subgroups. No correlation of the examined PET parameters with LN or DM was shown. In univariate survival analysis, both heterogeneity and tumor size were predictive for disease-specific survival, but only texture determined by entropy was determined as an independent factor in multivariate analysis (hazard ratio 7.48, p = .016). Overall survival was not significantly correlated to any examined parameter, most likely due to the high comorbidity in our cohort. Our study adds to the growing evidence that tumor

  7. Textural features in pre-treatment [F18]-FDG-PET/CT are correlated with risk of local recurrence and disease-specific survival in early stage NSCLC patients receiving primary stereotactic radiation therapy

    International Nuclear Information System (INIS)

    Pyka, Thomas; Bundschuh, Ralph A; Andratschke, Nicolaus; Mayer, Benedikt; Specht, Hanno M; Papp, Laszló; Zsótér, Norbert; Essler, Markus

    2015-01-01

    Textural features in FDG-PET have been shown to provide prognostic information in a variety of tumor entities. Here we evaluate their predictive value for recurrence and prognosis in NSCLC patients receiving primary stereotactic radiation therapy (SBRT). 45 patients with early stage NSCLC (T1 or T2 tumor, no lymph node or distant metastases) were included in this retrospective study and followed over a median of 21.4 months (range 3.1–71.1). All patients were considered non-operable due to concomitant disease and referred to SBRT as the primary treatment modality. Pre-treatment FDG-PET/CT scans were obtained from all patients. SUV and volume-based analysis as well as extraction of textural features based on neighborhood gray-tone difference matrices (NGTDM) and gray-level co-occurence matrices (GLCM) were performed using InterView Fusion™ (Mediso Inc., Budapest). The ability to predict local recurrence (LR), lymph node (LN) and distant metastases (DM) was measured using the receiver operating characteristic (ROC). Univariate and multivariate analysis of overall and disease-specific survival were executed. 7 out of 45 patients (16%) experienced LR, 11 (24%) LN and 11 (24%) DM. ROC revealed a significant correlation of several textural parameters with LR with an AUC value for entropy of 0.872. While there was also a significant correlation of LR with tumor size in the overall cohort, only texture was predictive when examining T1 (tumor diameter < = 3 cm) and T2 (>3 cm) subgroups. No correlation of the examined PET parameters with LN or DM was shown. In univariate survival analysis, both heterogeneity and tumor size were predictive for disease-specific survival, but only texture determined by entropy was determined as an independent factor in multivariate analysis (hazard ratio 7.48, p = .016). Overall survival was not significantly correlated to any examined parameter, most likely due to the high comorbidity in our cohort. Our study adds to the growing evidence

  8. Automated de novo phasing and model building of coiled-coil proteins.

    Science.gov (United States)

    Rämisch, Sebastian; Lizatović, Robert; André, Ingemar

    2015-03-01

    Models generated by de novo structure prediction can be very useful starting points for molecular replacement for systems where suitable structural homologues cannot be readily identified. Protein-protein complexes and de novo-designed proteins are examples of systems that can be challenging to phase. In this study, the potential of de novo models of protein complexes for use as starting points for molecular replacement is investigated. The approach is demonstrated using homomeric coiled-coil proteins, which are excellent model systems for oligomeric systems. Despite the stereotypical fold of coiled coils, initial phase estimation can be difficult and many structures have to be solved with experimental phasing. A method was developed for automatic structure determination of homomeric coiled coils from X-ray diffraction data. In a benchmark set of 24 coiled coils, ranging from dimers to pentamers with resolutions down to 2.5 Å, 22 systems were automatically solved, 11 of which had previously been solved by experimental phasing. The generated models contained 71-103% of the residues present in the deposited structures, had the correct sequence and had free R values that deviated on average by 0.01 from those of the respective reference structures. The electron-density maps were of sufficient quality that only minor manual editing was necessary to produce final structures. The method, named CCsolve, combines methods for de novo structure prediction, initial phase estimation and automated model building into one pipeline. CCsolve is robust against errors in the initial models and can readily be modified to make use of alternative crystallographic software. The results demonstrate the feasibility of de novo phasing of protein-protein complexes, an approach that could also be employed for other small systems beyond coiled coils.

  9. Extrap with iron-cored coils

    International Nuclear Information System (INIS)

    Lehnert, B.

    1985-05-01

    In Extrap configurations there is a high average beta value with respect to the plasma confinement volume. The externally imposed magnetic field which is required for stabilization therefore comes out to have a rather moderate strength, even under expected reactor conditions. As a consequence, this field can be generated not only by conventional external conductor arrangements, but also by iron-cored coils being operated below the saturation limit. A proposal for such iron-cored coil systems is presented in this paper. As compared to conventional conductors, this has the advantage of localizing the magnetic energy of the externally imposed magnetic field mainly to the discharge vessel and the plasma volume, thereby increasing the engineering beta value substantially. Also the problems of the coil stresses and of irradiation of the coils appear to become simplified, as well as replacement of the coil system. A main limitation of this proposal is due to combination of iron core saturation with the required stabilization effect from an ion Larmor radius of sufficient relative magnitude. This limitaion requires further investigation, especially in the full-scale reactor case. Also the modifications of the field geometry by iron core shaping needs further analysis. (Author)

  10. Effects of insulation on potted superconducting coils

    International Nuclear Information System (INIS)

    Zeller, A.F.; DeKamp, J.C.; Magsig, C.T.; Nolen, J.A.; McInturff, A.D.

    1989-01-01

    Test coils using identical wire but with either Formvar or Polyesterimid insulation were fabricated to determine the effects of insulation on training behavior. It was found that the type of insulation did not affect the training behavior. While considerable attention has been paid to epoxy formulations used for superconducting coils, little study has been devoted to the effects of the wire insulation on training behavior. If the insulation does not bind well with the epoxy, the wires will not be held securely in place, and training will be required to make the coil operate at its design limit. In fact, the coil may never reach its design current, showing considerable degredation. Conversely, if the epoxy-insulation reaction is to soften or weaken the insulation, then shorts and/or training may result. The authors have undertaken a study of the effects of the insulation on potted coils wet wound with Stycast 2850 FT epoxy. The wire was insulated with one of two insulting varnishes: Formvar (a polyvinyl formal resin) or Polyesterimid (a phenolic resin). Formvar is the standard insulation in the United States while Polyesterimid the European standard

  11. The design of the SULTAN inner coil

    International Nuclear Information System (INIS)

    Franken, W.M.P.; Spoorenberg, C.J.G.

    1981-12-01

    The background field of the first phase of the test facility SULTAN will be generated by two concentric solenoids: a 6 Tesla outer coil with a free bore of 1.3 m and an inner coil for increasing the field to 8 Tesla. The free bore (cold) will be 1.055 m. The final design of the 8 Tesla inner coil is described. The coil will operate at an overall current density of 23 x 10 6 A/m 2 . It will be cooled directly by forced flow supercritical helium. A hollow conductor is applied, composed of a rectangular copper tube and a 16 strands Rutherford cable, soldered on one side of the tube. The copper tube will be cold worked to cope with the high stress level (165 MPa). The design base (field and stress analysis, cooling, stability), the mechanical design and the instrumentation will be specified. The design and construction of the coil is a part of the collaboration between ECN and Holec Transformer Group

  12. Optimal design for MRI surface coils

    International Nuclear Information System (INIS)

    Rivera, M.; Vaquero, J.J.; Santos, A.; Pozo, F. del; Ruiz-Cabello, J.

    1997-01-01

    To demonstrate the possibility of designing and constructing specific surface coils or antennae for MRI viewing of each particular tissue producing better results than those provided by a general purpose surface coil. The study was performed by the Bioengineering and Telemedicine Group of Madrid Polytechnical University and was carried out at the Pluridisciplinary Institute of the Universidad Complutense in Madrid, using a BMT-47/40 BIOSPEC resonance unit from Bruker. Surface coils were custom-designed and constructed for each region to be studied, and optimized to make the specimen excitation field as homogeneous as possible, in addition to reducing the brightness artifact. First, images were obtained of a round, water phantom measuring 50 mm in diameter, after which images of laboratory rats and rabbits were obtained. The images thus acquired were compared with the results obtained with the coil provided by the manufacturer of the equipment, and were found to be of better quality, allowing the viewing of deeper tissue for the specimen as well as reducing the brightness artifact. The construction of surface coils for viewing specific tissues or anatomical regions improves image quality. The next step in this ongoing project will be the application of these concepts to units designed for use in humans. (Author) 14 refs

  13. Critical current studies of a HTS rectangular coil

    Energy Technology Data Exchange (ETDEWEB)

    Zhong, Z. [Department of Engineering, University of Cambridge (United Kingdom); Chudy, M., E-mail: Michal.chudy@stuba.sk [Graduate School of Technology Management, University of Pretoria (South Africa); Institute of Power and Applied Electrical Engineering, Slovak University of Technology in Bratislava (Slovakia); Ruiz, H.S. [Department of Engineering, University of Leicester, Leicester LE1 7RH (United Kingdom); Zhang, X.; Coombs, T. [Department of Engineering, University of Cambridge (United Kingdom)

    2017-05-15

    Highlights: • Unique square pancake coil was manufactured. • Measurements in relatively high magnetic field were performed. • Different sections of the coil were characterized. • Parts of the coil which are limiting critical current were identified. - Abstract: Nowadays, superconducting high field magnets are used in numerous applications due to their superior properties. High temperature superconductors (HTS) are usually used for production of circular pancake or racetrack coils. However different geometries of HTS coils might be required for some specific applications. In this study, the HTS coil wound on a rectangular frame was fully characterized in homogeneous DC background field. The study contains measurements of critical current angular dependencies. The critical current of the entire coil and two selected strands under different magnitudes and orientations of external magnetic fields are measured. The critical regions of the coil in different angular regimes are determined. This study brings better understanding of the in- field performance of HTS coils wound on frames with right-angles.

  14. Fabrication of the KSTAR toroidal field coil structure

    International Nuclear Information System (INIS)

    Choi, C.H.; Sa, J.W.; Park, H.K.; Hong, K.H.; Shin, H.; Kim, H.T.; Bak, J.S.; Lee, G.S.; Kwak, J.H.; Moon, H.G.; Yoon, H.H.; Lee, J.W.; Lee, S.K.; Song, J.Y.; Nam, K.M.; Byun, S.E.; Kim, H.C.; Ha, E.T.; Ahn, H.J.; Kim, D.S.; Lee, J.S.; Park, K.H.; Hong, C.D.

    2005-01-01

    The KSTAR toroidal field (TF) coil structure is under fabrication upon completion of engineering design and prototype construction. The prototype TF coil structure has been fabricated within allowable tolerances. Encasing of the prototype TF coil (TF00) in the prototype structure has been carried out through major processes involving a coil encasing, an enclosing weld, a vacuum pressure impregnation, and an outer surface machining. During the enclosing weld of the TF00 coil structure, we have measured temperatures and stresses on the coil surface. Assembly test had been performed with the TF00 coil structure. We have chosen Type 316LN as material of the TF coil structure. We used the narrow-gap TIG welding method. Doosan Heavy Industries and Construction Company (DHI) will complete the fabrication of the TF coil structure in Feb. 2006. (author)

  15. PET attenuation correction for rigid MR Tx/Rx coils from 176Lu background activity

    Science.gov (United States)

    Lerche, Christoph W.; Kaltsas, Theodoris; Caldeira, Liliana; Scheins, Jürgen; Rota Kops, Elena; Tellmann, Lutz; Pietrzyk, Uwe; Herzog, Hans; Shah, N. Jon

    2018-02-01

    One challenge for PET-MR hybrid imaging is the correction for attenuation of the 511 keV annihilation radiation by the required RF transmit and/or RF receive coils. Although there are strategies for building PET transparent Tx/Rx coils, such optimised coils still cause significant attenuation of the annihilation radiation leading to artefacts and biases in the reconstructed activity concentrations. We present a straightforward method to measure the attenuation of Tx/Rx coils in simultaneous MR-PET imaging based on the natural 176Lu background contained in the scintillator of the PET detector without the requirement of an external CT scanner or PET scanner with transmission source. The method was evaluated on a prototype 3T MR-BrainPET produced by Siemens Healthcare GmbH, both with phantom studies and with true emission images from patient/volunteer examinations. Furthermore, the count rate stability of the PET scanner and the x-ray properties of the Tx/Rx head coil were investigated. Even without energy extrapolation from the two dominant γ energies of 176Lu to 511 keV, the presented method for attenuation correction, based on the measurement of 176Lu background attenuation, shows slightly better performance than the coil attenuation correction currently used. The coil attenuation correction currently used is based on an external transmission scan with rotating 68Ge sources acquired on a Siemens ECAT HR  +  PET scanner. However, the main advantage of the presented approach is its straightforwardness and ready availability without the need for additional accessories.

  16. Integrated B1+ Mapping for Hyperpolarized 13C MRI in a Clinical Setup using Multi-Channel Receive Arrays

    DEFF Research Database (Denmark)

    Hansen, Rie Beck; Shin, Peter J.; Gordon, Jeremy W.

    inhomogeneous transmit coils, and because kinetic modeling based on incorrect flip angles can lead to incorrect rate constant estimations. This study demonstrates the feasibility of integrated B1+ mapping for large volume thermal and hyperpolarized phantoms in a clinical setup using a clamshell transmit coil...... and a 16-channel receive array, and a 3D stack-of-spirals sequence. Phase-sensitive coil-combination was achieved using ESPIRiT....

  17. CS model coil experimental log book

    Energy Technology Data Exchange (ETDEWEB)

    Nishijima, Gen; Sugimoto, Makoto; Nunoya, Yoshihiko; Wakabayashi, Hiroshi; Tsuji, Hiroshi [Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan). Naka Fusion Research Establishment

    2001-02-01

    Charging test of the ITER CS Model Coil which is the world's largest superconducting pulse coil and the CS Insert Coil had started at April 11, 2000 and had completed at August 18, 2000. In the campaign, total shot numbers were 356 and the size of the data file in the DAS (Data Acquisition System) was over 20 GB. This report is a database that consists of the log list and the log sheets of every shot. One can access the database, make a search, and browse results via Internet (http://1ogwww.naka.jaeri.go.jp). The database will be useful to quick search to choose necessary shots. (author)

  18. OCLATOR (One Coil Low Aspect Toroidal Reactor)

    International Nuclear Information System (INIS)

    Yoshikawa, S.

    1980-02-01

    A new approach to construct a tokamak-type reactor(s) is presented. Basically the return conductors of toroidal field coils are eliminated and the toroidal field coil is replaced by one single large coil, around which there will be placed several tokamaks or other toroidal devices. The elimination of return conductors should, in addition to other advantages, improve the accessibility and maintainability of the tokamaks and offer a possible alternative to the search for special materials to withstand large neutron wall loading, as the frequency of changeover would be increased due to minimum downtime. It also makes it possible to have a low aspect ratio tokamak which should improve the β limit, so that a low toroidal magnetic field strength might be acceptable, meaning that the NbTi superconducting wire could be used. This system is named OCLATOR

  19. MFTF test coil construction and performance

    International Nuclear Information System (INIS)

    Cornish, D.N.; Zbasnik, J.P.; Leber, R.L.; Hirzel, D.G.; Johnston, J.E.; Rosdahl, A.R.

    1978-01-01

    A solenoid coil, 105 cm inside the 167 cm outside diameter, has been constructed and tested to study the performance of the stabilized Nb--Ti conductor to be used in the Mirror Fusion Test Facility (MFTF) being built at Lawrence Livermore Laboratory. The insulation system of the test coil is identical to that envisioned for MFTF. Cold-weld joints were made in the conductor at the start and finish of each layer; heaters were fitted to some of these joints and also to the conductor at various locations in the winding. This paper gives details of the construction of the coil and the results of the tests carried out to determine its propagation and recovery characteristics

  20. Considerations against a force compensated coil

    International Nuclear Information System (INIS)

    Hassenzahl, W.

    1988-08-01

    The cost of structural components in a large superconducting coil may well exceed the coil and cryostat cost. As a result, the idea of constructing a system composed of two different coil types assembled in such a way that the sources balance and reduce the total structural requirement is oft proposed. A suitable geometry has never been found for the fundamental reason that there can be no force compensated solution. In this paper, the general problem is presented and an analysis of the energy stored and stresses produced in the structure are described in a fundamental way. Finally, the relation between structural mass M and stored energy E, M ≥/rho/E/σ/sub w/, that is valid for all magnetic systems is developed, where /rho/ is the density of the structure and σ/sub w/ is the working stress in the structure. 12 refs., 2 figs

  1. Considerations against a force compensated coil

    International Nuclear Information System (INIS)

    Hassenzahl, W.

    1988-08-01

    The cost of structural components in a large superconducting coil may well exceed the coil and cryostat cost. As a result, the idea of constructing a system composed of two different coil types assembled in such a way that the forces balance and reduce the total structural requirement is oft proposed. A suitable geometry has never been found for the fundamental reason that there can be no force compensated solution. In this paper, the general problem is presented and an analysis of the energy stored and stresses produced in the structure are described in a fundamental way. Finally, the relation between structural mass M and stored energy E, M ≥ /rho/E/σ/sub w/, that is valid for all magnetic systems is developed, where /rho/ is the density of the structure and σ/sub w/ is the working stress in the structure. 8 refs., 2 figs

  2. Acoustic rainbow trapping by coiling up space

    KAUST Repository

    Ni, Xu

    2014-11-13

    We numerically realize the acoustic rainbow trapping effect by tapping an air waveguide with space-coiling metamaterials. Due to the high refractive-index of the space-coiling metamaterials, our device is more compact compared to the reported trapped-rainbow devices. A numerical model utilizing effective parameters is also calculated, whose results are consistent well with the direct numerical simulation of space-coiling structure. Moreover, such device with the capability of dropping different frequency components of a broadband incident temporal acoustic signal into different channels can function as an acoustic wavelength division de-multiplexer. These results may have potential applications in acoustic device design such as an acoustic filter and an artificial cochlea.

  3. Isabelle dipole and quadrupole coil configurations

    International Nuclear Information System (INIS)

    Dahl, P.F.; Hahn, H.

    1980-01-01

    The coil configurations of the ISABELLE dipole and quadrupole magnets have been reviewed and a number of improvements were suggested for incorporation into the final design. The coil designs are basically single layer multiple block approximations to cosine current distributions, wound from a high aspect ratio non-keystoned braided conductor. The blocks are separated by knife-edge wedges to maximize the quench propagation velocity. The current density variation is obtained by an appropriate distribution of the spacer turns and, to a lesser degree, by the wedge locations. The use of inert turns is necessary to minimize the peak field enhancement both in the ends and in the two dimensional section. Schemes for deriving turns distributions yielding harmonic coefficients satisfying the stringent ISABELLE tolerances on field uniformity, while allowing for simplicity in winding and taking into account quench propagation considerations, will be discussed, as well as our approach to the coil end configuration

  4. FRC translation into a compression coil

    International Nuclear Information System (INIS)

    Chrien, R.E.

    1985-01-01

    Several features of the problem of FRC translation into a compression coil are considered. First, the magnitude of the guide field is calculated and found to exceed that which would be applied to a flux conserver. Second, energy conservation is applied to FRC translation from a flux conserver into a compression coil. It is found that a significant temperature decrease is required for translation to be energetically possible. The temperature change depends on the external inductance in the compression circuit. An analogous case is that of a compression region composed of a compound magnet; in this case the temperature change depends on the ratio of inner and outer coil radii. Finally, the kinematics of intermediate translation states are calculated using an ''abrupt transition'' model. It is found, in this model, that the FRC must overcome a potential hill during translation, which requires a small initial velocity

  5. Acoustic rainbow trapping by coiling up space

    KAUST Repository

    Ni, Xu; Wu, Ying; Chen, Ze-Guo; Zheng, Li-Yang; Xu, Ye-Long; Nayar, Priyanka; Liu, Xiao-Ping; Lu, Ming-Hui; Chen, Yan-Feng

    2014-01-01

    We numerically realize the acoustic rainbow trapping effect by tapping an air waveguide with space-coiling metamaterials. Due to the high refractive-index of the space-coiling metamaterials, our device is more compact compared to the reported trapped-rainbow devices. A numerical model utilizing effective parameters is also calculated, whose results are consistent well with the direct numerical simulation of space-coiling structure. Moreover, such device with the capability of dropping different frequency components of a broadband incident temporal acoustic signal into different channels can function as an acoustic wavelength division de-multiplexer. These results may have potential applications in acoustic device design such as an acoustic filter and an artificial cochlea.

  6. High voltage investigations for ITER coils

    International Nuclear Information System (INIS)

    Fink, S.; Fietz, W.H.

    2006-01-01

    The superconducting ITER magnets will be excited with high voltage during operation and fast discharge. Because the coils are complex systems the internal voltage distribution can differ to a large extent from the ideal linear voltage distribution. In case of fast excitations internal voltages between conductor and radial plate of a TF coil can be even higher than the terminal voltage of 3.5 kV to ground which appears during a fast discharge without a fault. Hence the determination of the transient voltage distribution is important for a proper insulation co-ordination and will provide a necessary basis for the verification of the individual insulation design and the choice of test voltages and waveforms. Especially the extent of internal overvoltages in case of failures, e. g. malfunction of discharge units and / or arcing is of special interest. Transient calculations for the ITER TF coil system have been performed for fast discharge and fault scenarios to define test voltages for ITER TF. The conductor and radial plate insulation of the ITER TF Model Coil were exposed at room temperature to test voltages derived from the results from these calculations. Breakdown appeared during the highest AC voltage step. A fault scenario for the TF fast discharge system is presented where one fault triggers a second fault, leading to considerable voltage stress. In addition a FEM model of Poloidal Field Coil 3 for the determination of the parameters of a detailed network model is presented in order to prepare detailed investigations of the transient voltage behaviour of the PF coils. (author)

  7. Stent-assisted coil embolization for cavernous carotid artery aneurysms.

    Science.gov (United States)

    Kono, Kenichi; Shintani, Aki; Okada, Hideo; Tanaka, Yuko; Terada, Tomoaki

    2014-01-01

    Internal carotid artery (ICA) occlusion with or without a bypass surgery is the traditional treatment for cavernous sinus (CS) aneurysms with cranial nerve (CN) dysfunction. Coil embolization without stents frequently requires retreatment because of the large size of CS aneurysms. We report the mid-term results of six unruptured CS aneurysms treated with stent-assisted coil embolization (SACE). The mean age of the patients was 72 years. The mean size of the aneurysms was 19.8 mm (range: 13-26 mm). Before treatment, four patients presented with CN dysfunction and two patients had no symptoms. SACE was performed under local or general anesthesia in three patients each. Mean packing density was 29.1% and tight packing was achieved. There were no neurological complications. CN dysfunction was cured in three patients (75%) and partly resolved in one patient (25%). Transient new CN dysfunction was observed in two patients (33%). Clinical and imaging follow-up ranged from 6 to 26 months (median: 16 months). Recanalization was observed in three patients (50%; neck remnant in two patients and dome filling in one patient), but no retreatment has yet been required. No recurrence of CN dysfunction has occurred yet. In summary, SACE increases packing density and may reduce requirement of retreatment with an acceptable cure rate of CN dysfunction. SACE may be a superior treatment for coiling without stents and be an alternative treatment of ICA occlusion for selected patients, such as older patients and those who require a high-flow bypass surgery or cannot receive general anesthesia.

  8. Study of electric phenomena in energy dumping of LCT coil

    International Nuclear Information System (INIS)

    Oka, Koichi; Tsuji, Hiroshi; Nishi, Masataka; Shimamoto, Susumu

    1980-03-01

    In IEA-LCT coil, electric phenomena in energy dumping were studied analytically and experimentally. Protection resistance of the Japanese LCT coil is chosen as 0.1 Ω considering the quenching voltage, so that temperature rise of the coil is no problem. Energy dumping characteristic of the six-coil system is calculated under different conditions. It is concluded that simultaneous dumping of all the coils with the equivalent resistance values of protection is necessary. Flashover voltage tests of the model in 4.2 K liquid helium, 4.2 K gas helium and 4.2 K boiling helium show margin in practical quenching voltage of the coil. (author)

  9. Resistive demountable toroidal-field coils for tokamak reactors

    International Nuclear Information System (INIS)

    Jassby, D.L.; Jacobsen, R.A.; Kalnavarns, J.; Masson, L.S.; Sekot, J.P.

    1981-07-01

    Readily demountable TF (toroidal-field) coils allow complete access to the internal components of a tokamak reactor for maintenance of replacement. The requirement of readily demountable joints dictates the use of water-cooled resistive coils, which have a host of decisive advantages over superconducting coils. Previous papers have shown that resistive TF coils for tokamak reactors can operate in the steady state with acceptable power dissipation (typically, 175 to 300 MW). This paper summarizes results of parametric studies of size optimization of rectangular TF coils and of a finite-element stress analysis, and examines several candidate methods of implementing demountable joints for rectangular coils constructed of plate segments

  10. Stress distributions of coils for toroidal magnetic field

    International Nuclear Information System (INIS)

    Kajita, Tateo; Miyamoto, Kenro.

    1976-01-01

    The stress distributions of a D shaped coil and a circular coil are computed by the finite element method. The dependences of the stress distribution on the geometrical parameters of the stress distribution on the geometrical parameters of the coils and supporting methods are examined. The maximum amount of the stress in the D shaped coil is not much smaller than that of the circular one. However, the stress distribution of the D shaped coil becomes much more uniform. The supporting method has as much effect as the geometrical parameters of the coil on the stress distribution. (auth.)

  11. A novel coil array for combined TMS/fMRI experiments at 3 T.

    Science.gov (United States)

    Navarro de Lara, Lucia I; Windischberger, Christian; Kuehne, Andre; Woletz, Michael; Sieg, Jürgen; Bestmann, Sven; Weiskopf, Nikolaus; Strasser, Bernhard; Moser, Ewald; Laistler, Elmar

    2015-11-01

    To overcome current limitations in combined transcranial magnetic stimulation (TMS) and functional magnetic resonance imaging (fMRI) studies by employing a dedicated coil array design for 3 Tesla. The state-of-the-art setup for concurrent TMS/fMRI is to use a large birdcage head coil, with the TMS between the subject's head and the MR coil. This setup has drawbacks in sensitivity, positioning, and available imaging techniques. In this study, an ultraslim 7-channel receive-only coil array for 3 T, which can be placed between the subject's head and the TMS, is presented. Interactions between the devices are investigated and the performance of the new setup is evaluated in comparison to the state-of-the-art setup. MR sensitivity obtained at the depth of the TMS stimulation is increased by a factor of five. Parallel imaging with an acceleration factor of two is feasible with low g-factors. Possible interactions between TMS and the novel hardware were investigated and were found negligible. The novel coil array is safe, strongly improves signal-to-noise ratio in concurrent TMS/fMRI experiments, enables parallel imaging, and allows for flexible positioning of the TMS on the head while ensuring efficient TMS stimulation due to its ultraslim design. © 2014 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.

  12. Zero current measurements using the Rogowski coil

    International Nuclear Information System (INIS)

    Gregor, J.; Jakubova, I.; Kadlec, P.; Senk, J.; Vavra, Z.

    1997-01-01

    The zero current measurements using the Rogowski coil carried out on the model of the extinguishing chamber of hv SF 6 circuit breaker with self-flow generation are presented in the paper. The time course of the post-arc current obtained by numerical integration of the measured induced voltage of the Rogowski coil gives information not only about the value of the residual current after the successful interruption but also about the current changes connected with the dynamic behaviour of the arc during its quenching. (author)

  13. Self-assembling segmented coiled tubing

    Science.gov (United States)

    Raymond, David W.

    2016-09-27

    Self-assembling segmented coiled tubing is a concept that allows the strength of thick-wall rigid pipe, and the flexibility of thin-wall tubing, to be realized in a single design. The primary use is for a drillstring tubular, but it has potential for other applications requiring transmission of mechanical loads (forces and torques) through an initially coiled tubular. The concept uses a spring-loaded spherical `ball-and-socket` type joint to interconnect two or more short, rigid segments of pipe. Use of an optional snap ring allows the joint to be permanently made, in a `self-assembling` manner.

  14. Multiple coil closure of isolated aortopulmonary collateral

    Directory of Open Access Journals (Sweden)

    Padhi Sumanta

    2010-01-01

    Full Text Available A 7-month-old girl was diagnosed to have large aortopulmonary collateral during evaluation for congestive heart failure. There was no other evidence of cardiopulmonary disease. The collateral was successfully closed with multiple coils delivered sequentially. We describe the issues associated during closure of the aortopulmonary collateral in this case. To the best of our knowledge, this is the first reported case of large aortopulmonary collateral presenting with heart failure in an otherwise structurally normal heart that was closed successfully with multiple coils delivered sequentially.

  15. Superconducting Coil Winding Machine Control System

    Energy Technology Data Exchange (ETDEWEB)

    Nogiec, J. M. [Fermilab; Kotelnikov, S. [Fermilab; Makulski, A. [Fermilab; Walbridge, D. [Fermilab; Trombly-Freytag, K. [Fermilab

    2016-10-05

    The Spirex coil winding machine is used at Fermilab to build coils for superconducting magnets. Recently this ma-chine was equipped with a new control system, which al-lows operation from both a computer and a portable remote control unit. This control system is distributed between three layers, implemented on a PC, real-time target, and FPGA, providing respectively HMI, operational logic and direct controls. The system controls motion of all mechan-ical components and regulates the cable tension. Safety is ensured by a failsafe, redundant system.

  16. Fine-tuning of protein domain boundary by minimizing potential coiled coil regions

    International Nuclear Information System (INIS)

    Iwaya, Naoko; Goda, Natsuko; Unzai, Satoru; Fujiwara, Kenichiro; Tanaka, Toshiki; Tomii, Kentaro; Tochio, Hidehito; Shirakawa, Masahiro; Hiroaki, Hidekazu

    2007-01-01

    Structural determination of individual protein domains isolated from multidomain proteins is a common approach in the post-genomic era. Novel and thus uncharacterized domains liberated from intact proteins often self-associate due to incorrectly defined domain boundaries. Self-association results in missing signals, poor signal dispersion and a low signal-to-noise ratio in 1 H- 15 N HSQC spectra. We have found that a putative, non-canonical coiled coil region close to a domain boundary can cause transient hydrophobic self-association and monomer-dimer equilibrium in solution. Here we propose a rational method to predict putative coiled coil regions adjacent to the globular core domain using the program COILS. Except for the amino acid sequence, no preexisting knowledge concerning the domain is required. A small number of mutant proteins with a minimized coiled coil region have been rationally designed and tested. The engineered domains exhibit decreased self-association as assessed by 1 H- 15 N HSQC spectra with improved peak dispersion and sharper cross peaks. Two successful examples of isolating novel N-terminal domains from AAA-ATPases are demonstrated. Our method is useful for the experimental determination of domain boundaries suited for structural genomics studies

  17. Fine-tuning of protein domain boundary by minimizing potential coiled coil regions.

    Science.gov (United States)

    Iwaya, Naoko; Goda, Natsuko; Unzai, Satoru; Fujiwara, Kenichiro; Tanaka, Toshiki; Tomii, Kentaro; Tochio, Hidehito; Shirakawa, Masahiro; Hiroaki, Hidekazu

    2007-01-01

    Structural determination of individual protein domains isolated from multidomain proteins is a common approach in the post-genomic era. Novel and thus uncharacterized domains liberated from intact proteins often self-associate due to incorrectly defined domain boundaries. Self-association results in missing signals, poor signal dispersion and a low signal-to-noise ratio in (1)H-(15)N HSQC spectra. We have found that a putative, non-canonical coiled coil region close to a domain boundary can cause transient hydrophobic self-association and monomer-dimer equilibrium in solution. Here we propose a rational method to predict putative coiled coil regions adjacent to the globular core domain using the program COILS. Except for the amino acid sequence, no preexisting knowledge concerning the domain is required. A small number of mutant proteins with a minimized coiled coil region have been rationally designed and tested. The engineered domains exhibit decreased self-association as assessed by (1)H-(15)N HSQC spectra with improved peak dispersion and sharper cross peaks. Two successful examples of isolating novel N-terminal domains from AAA-ATPases are demonstrated. Our method is useful for the experimental determination of domain boundaries suited for structural genomics studies.

  18. Four signature motifs define the first class of structurally related large coiled-coil proteins in plants.

    Directory of Open Access Journals (Sweden)

    Meier Iris

    2002-04-01

    Full Text Available Abstract Background Animal and yeast proteins containing long coiled-coil domains are involved in attaching other proteins to the large, solid-state components of the cell. One subgroup of long coiled-coil proteins are the nuclear lamins, which are involved in attaching chromatin to the nuclear envelope and have recently been implicated in inherited human diseases. In contrast to other eukaryotes, long coiled-coil proteins have been barely investigated in plants. Results We have searched the completed Arabidopsis genome and have identified a family of structurally related long coiled-coil proteins. Filament-like plant proteins (FPP were identified by sequence similarity to a tomato cDNA that encodes a coiled-coil protein which interacts with the nuclear envelope-associated protein, MAF1. The FPP family is defined by four novel unique sequence motifs and by two clusters of long coiled-coil domains separated by a non-coiled-coil linker. All family members are expressed in a variety of Arabidopsis tissues. A homolog sharing the structural features was identified in the monocot rice, indicating conservation among angiosperms. Conclusion Except for myosins, this is the first characterization of a family of long coiled-coil proteins in plants. The tomato homolog of the FPP family binds in a yeast two-hybrid assay to a nuclear envelope-associated protein. This might suggest that FPP family members function in nuclear envelope biology. Because the full Arabidopsis genome does not appear to contain genes for lamins, it is of interest to investigate other long coiled-coil proteins, which might functionally replace lamins in the plant kingdom.

  19. Design of a Nested Eight-Channel Sodium and Four-Channel Proton Coil for 7 Tesla Knee Imaging

    Science.gov (United States)

    Brown, Ryan; Madelin, Guillaume; Lattanzi, Riccardo; Chang, Gregory; Regatte, Ravinder R.; Sodickson, Daniel K.; Wiggins, Graham C.

    2012-01-01

    The critical design aim for a dual-tuned sodium/proton coil is to maximize sodium sensitivity and transmit field (B1+) homogeneity while simultaneously providing adequate proton sensitivity and homogeneity. While most dual-frequency coils utilize lossy high-impedance trap circuits or PIN diodes to allow dual-resonance, we explored a nested-coil design for sodium/proton knee imaging at 7T. A stand-alone eight-channel sodium receive array was implemented without standard dual-resonance circuitry to provide improved sodium signal-to-noise ratio (SNR) over a volume coil. A detunable sodium birdcage was added for homogeneous sodium excitation and a four-channel proton transmit-receive array was added to provide anatomical reference imaging and B0 shimming capability. Both modules were implemented with minimal disturbance to the eight-channel sodium array by managing their respective resonances and geometrical arrangement. In vivo sodium SNR was 1.2 to 1.7 times greater in the developed eight-channel array than in a mono-nuclear sodium birdcage coil, while the developed four-channel proton array provided SNR similar to that of a commercial mono-nuclear proton birdcage coil. PMID:22887123

  20. Dielectric properties of 3D-printed materials for anatomy specific 3D-printed MRI coils

    Science.gov (United States)

    Behzadnezhad, Bahareh; Collick, Bruce D.; Behdad, Nader; McMillan, Alan B.

    2018-04-01

    Additive manufacturing provides a low-cost and rapid means to translate 3D designs into the construction of a prototype. For MRI, this type of manufacturing can be used to construct various components including the structure of RF coils. In this paper, we characterize the material properties (dielectric constant and loss tangent) of several common 3D-printed polymers in the MRI frequency range of 63-300 MHz (for MRI magnetic field strengths of 1.5-7 T), and utilize these material properties in full-wave electromagnetic simulations to design and construct a very low-cost subject/anatomy-specific 3D-printed receive-only RF coil that fits close to the body. We show that the anatomy-specific coil exhibits higher signal-to-noise ratio compared to a conventional flat surface coil.

  1. Time-domain finite-difference/finite-element hybrid simulations of radio frequency coils in magnetic resonance imaging

    International Nuclear Information System (INIS)

    Wang Shumin; Duyn, Jeff H

    2008-01-01

    A hybrid method that combines the finite-difference time-domain (FDTD) method and the finite-element time-domain (FETD) method is presented for simulating radio-frequency (RF) coils in magnetic resonance imaging. This method applies a high-fidelity FETD method to RF coils, while the human body is modeled with a low-cost FDTD method. Since the FDTD and the FETD methods are applied simultaneously, the dynamic interaction between RF coils and the human body is fully accounted for. In order to simplify the treatment of the highly irregular FDTD/FETD interface, composite elements are proposed. Two examples are provided to demonstrate the validity and effectiveness of the hybrid method in high-field receive-and-transmit coil design. This approach is also applicable to general bio-electromagnetic simulations

  2. Simultaneous recordings of human microsaccades and drifts with a contemporary video eye tracker and the search coil technique.

    Directory of Open Access Journals (Sweden)

    Michael B McCamy

    Full Text Available Human eyes move continuously, even during visual fixation. These "fixational eye movements" (FEMs include microsaccades, intersaccadic drift and oculomotor tremor. Research in human FEMs has grown considerably in the last decade, facilitated by the manufacture of noninvasive, high-resolution/speed video-oculography eye trackers. Due to the small magnitude of FEMs, obtaining reliable data can be challenging, however, and depends critically on the sensitivity and precision of the eye tracking system. Yet, no study has conducted an in-depth comparison of human FEM recordings obtained with the search coil (considered the gold standard for measuring microsaccades and drift and with contemporary, state-of-the art video trackers. Here we measured human microsaccades and drift simultaneously with the search coil and a popular state-of-the-art video tracker. We found that 95% of microsaccades detected with the search coil were also detected with the video tracker, and 95% of microsaccades detected with video tracking were also detected with the search coil, indicating substantial agreement between the two systems. Peak/mean velocities and main sequence slopes of microsaccades detected with video tracking were significantly higher than those of the same microsaccades detected with the search coil, however. Ocular drift was significantly correlated between the two systems, but drift speeds were higher with video tracking than with the search coil. Overall, our combined results suggest that contemporary video tracking now approaches the search coil for measuring FEMs.

  3. Numerical study of the influence of geometrical characteristics of a vertical helical coil on a bubbly flow

    Science.gov (United States)

    Saffari, H.; Moosavi, R.

    2014-11-01

    In this article, turbulent single-phase and two-phase (air-water) bubbly fluid flows in a vertical helical coil are analyzed by using computational fluid dynamics (CFD). The effects of the pipe diameter, coil diameter, coil pitch, Reynolds number, and void fraction on the pressure loss, friction coefficient, and flow characteristics are investigated. The Eulerian-Eulerian model is used in this work to simulate the two-phase fluid flow. Three-dimensional governing equations of continuity, momentum, and energy are solved by using the finite volume method. The k- ɛ turbulence model is used to calculate turbulence fluctuations. The SIMPLE algorithm is employed to solve the velocity and pressure fields. Due to the effect of a secondary force in helical pipes, the friction coefficient is found to be higher in helical pipes than in straight pipes. The friction coefficient increases with an increase in the curvature, pipe diameter, and coil pitch and decreases with an increase in the coil diameter and void fraction. The close correlation between the numerical results obtained in this study and the numerical and empirical results of other researchers confirm the accuracy of the applied method. For void fractions up to 0.1, the numerical results indicate that the friction coefficient increases with increasing the pipe diameter and keeping the coil pitch and diameter constant and decreases with increasing the coil diameter. Finally, with an increase in the Reynolds number, the friction coefficient decreases, while the void fraction increases.

  4. Characteristics of bowl-shaped coils for transcranial magnetic stimulation

    Science.gov (United States)

    Yamamoto, Keita; Suyama, Momoko; Takiyama, Yoshihiro; Kim, Dongmin; Saitoh, Youichi; Sekino, Masaki

    2015-05-01

    Transcranial magnetic stimulation (TMS) has recently been used as a method for the treatment of neurological and psychiatric diseases. Daily TMS sessions can provide continuous therapeutic effectiveness, and the installation of TMS systems at patients' homes has been proposed. A figure-eight coil, which is normally used for TMS therapy, induces a highly localized electric field; however, it is challenging to achieve accurate coil positioning above the targeted brain area using this coil. In this paper, a bowl-shaped coil for stimulating a localized but wider area of the brain is proposed. The coil's electromagnetic characteristics were analyzed using finite element methods, and the analysis showed that the bowl-shaped coil induced electric fields in a wider area of the brain model than a figure-eight coil. The expanded distribution of the electric field led to greater robustness of the coil to the coil-positioning error. To improve the efficiency of the coil, the relationship between individual coil design parameters and the resulting coil characteristics was numerically analyzed. It was concluded that lengthening the outer spherical radius and narrowing the width of the coil were effective methods for obtaining a more effective and more uniform distribution of the electric field.

  5. Low temperature synthesis of coiled carbon nanotubes and their magnetic properties

    Science.gov (United States)

    Krishna, Vemula Mohana; Somanathan, T.; Manikandan, E.

    2018-04-01

    In this paper, coiled like structure of carbon nanotubes (c-CNTs) have been effectively grown on bi-metal substituted α-alumina nanoparticles catalyst by chemical vapor deposition (CVD) system. Highly graphitized and dense bundles of carbon product were attained at a low temperature of 550 °C. The coiled carbon nanostructures in very longer lengths were noticed by field emission scanning electron microscope (FESEM) observation. Furthermore, high purity material was achieved, which correlates the energy dispersive x-ray spectroscopy (EDX) analysis. High resolution transmission electron microscope (HRTEM) revealed the diameter and graphitization of coiled structures. The superparamagnetic like behavior was observed at room temperature for the as-synthesized product, which was found by VSM investigation.

  6. Magnetic induction pneumography: a planar coil system for continuous monitoring of lung function via contactless measurements

    Directory of Open Access Journals (Sweden)

    Doga Gursoy

    2010-11-01

    Full Text Available Continuous monitoring of lung function is of particular interest to the mechanically ventilated patients during critical care. Recent studies have shown that magnetic induction measurements with single coils provide signals which are correlated with the lung dynamics and this idea is extended here by using a 5 by 5 planar coil matrix for data acquisition in order to image the regional thoracic conductivity changes. The coil matrix can easily be mounted onto the patient bed, and thus, the problems faced in methods that use contacting sensors can readily be eliminated and the patient comfort can be improved. In the proposed technique, the data are acquired by successively exciting each coil in order to induce an eddy-current density within the dorsal tissues and measuring the corresponding response magnetic field strength by the remaining coils. The recorded set of data is then used to reconstruct the internal conductivity distribution by means of algorithms that minimize the residual norm between the estimated and measured data. To investigate the feasibility of the technique, the sensitivity maps and the point spread functions at different locations and depths were studied. To simulate a realistic scenario, a chest model was generated by segmenting the tissue boundaries from NMR images. The reconstructions of the ventilation distribution and the development of an edematous lung injury were presented. The imaging artifacts caused by either the incorrect positioning of the patient or the expansion of the chest wall due to breathing were illustrated by simulations.

  7. Intersegment interactions and helix-coil transition within the generalized model of polypeptide chains approach

    Science.gov (United States)

    Badasyan, A. V.; Hayrapetyan, G. N.; Tonoyan, Sh. A.; Mamasakhlisov, Y. Sh.; Benight, A. S.; Morozov, V. F.

    2009-09-01

    The generalized model of polypeptide chains is extended to describe the helix-coil transition in a system comprised of two chains interacting side-by-side. The Hamiltonian of the model takes into account four possible types of interactions between repeated units of the two chains, i.e., helix-helix, helix-coil, coil-helix, and coil-coil. Analysis reveals when the energy Ihh+Icc of (h-h, c-c) interactions overwhelms the energy Ihc+Ich of mixed (h-c, c-h) interactions, the correlation length rises substantially, resulting in narrowing of the transition interval. In the opposite case, when Ihh+Icc

  8. Double microcatheter technique for coiling intracranial aneurysms with unfavorable configurations

    Directory of Open Access Journals (Sweden)

    WANG Shu-yuan

    2013-03-01

    . Among the 33 cases, only 1 case receiving follow-up angiography 1 year after operation showed the coils near the neck were slightly compressed and presented a "dog ear" like recanalization. Conclusion According to the clinical experience with complicated aneurysms, double microcatheter technique is feasible, safe and effective for coil embolization of aneurysms with unfavorable configurations.

  9. Comparison of edge plasma perturbation during ELM control using one vs. two toroidal rows of RMP coils in ITER similar shaped plasmas on DIII-D

    Energy Technology Data Exchange (ETDEWEB)

    Fenstermacher, M.E., E-mail: fenstermacher@fusion.gat.co [Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, California 94551 (United States); Evans, T.E.; Osborne, T.H.; Schaffer, M.J.; DeGrassie, J.S.; Gohil, P.; Groebner, R.J. [General Atomics, P.O. Box 85608, San Diego, California 92186-5608 (United States); Moyer, R.A. [University of California, San Diego, 9500 Gilman Dr., La Jolla, California 92093 (United States)

    2009-06-15

    Large Type-I edge localized modes (ELMs) were suppressed by n = 3 resonant magnetic perturbations (RMPs) from a set of internal coils in plasmas with an ITER similar shape at the ITER pedestal collisionality, nu{sub e}*approx0.1 and low edge safety factor (q{sub 95} approx 3.6), with either a single toroidal row of the internal RMP coils or two poloidally separated rows of coils. ELM suppression with a single row of internal coils was achieved at approximately the same q{sub 95} surface-averaged perturbation field as with two rows of coils, but required higher current per coil. Maintaining complete suppression of ELMs using n = 3 RMPs from a single toroidal row of internal coils was less robust to variations in input neutral beam injection torque than previous ELM suppression cases using both rows of internal coils. With either configuration of RMP coils, maximum ELM size is correlated with the width of the edge region having good overlap of the magnetic islands from vacuum field calculations.

  10. TEXT poloidal coil systems power supplies

    International Nuclear Information System (INIS)

    Hutchins, S.H.; Brower, D.F.

    1977-01-01

    TEXT is a convertional iron core tokamak which will have a toroidal field of 3.0 Tesla produced by room temperature copper coils and a maximum plasma current pulse of 400 kA induced by a 40 turn Ohmic Heating coil. The major radius is 100 cm and the minor radius of the plasma is 28 cm. The machine is intended for basic research in tokamak plasma physics and atomic physics and is designed primarily to provide a stable hot plasma, extremely good diagnostic access, and reliable operation. The discharge pulse length will be 300 msec and the repetition period 120 seconds. Power for the toroidal field coils and for the ohmic heating supply is provided by a 100 MVA energy storage alternator. The vertical field, horizontal field, fast positioning, and discharge cleaning power supply systems are powered from the Tokamak Laboratory power mains. The ohmic heating power system consists of an SCR controlled premagnetizing supply and commutation circuit, the main ohmic heating capacitor bank to provide plasma breakdown and current rise, and an SCR controlled power supply which sustains plasma current during the 300 ms pulse. The vertical field power system uses a small capacitor bank and an SCR controlled supply. The horizontal field has a reversible SCR controlled supply, and the fast positioning coils are powered by bipolar output transistor controlled supplies. This paper describes the loads, required wave forms, and the specifications for these power supply systems

  11. Coiling of ruptured pericallosal artery aneurysms.

    NARCIS (Netherlands)

    Menovsky, T.; Rooij, W.J.J. van; Sluzewski, M.; Wijnalda, D.

    2002-01-01

    OBJECTIVE: To assess the technical feasibility of treating ruptured pericallosal artery aneurysms with detachable coils and to evaluate the anatomic and clinical results. METHODS: Over a period of 27 months, 12 patients with a ruptured pericallosal artery aneurysm were treated with detachable

  12. Transcatheter Coil Embolization of Splenic Artery Aneurysm

    International Nuclear Information System (INIS)

    Yamamoto, Satoshi; Hirota, Shozo; Maeda, Hiroaki; Achiwa, Sachiko; Arai, Keisuke; Kobayashi, Kaoru; Nakao, Norio

    2008-01-01

    The purpose of this study was to evaluate clinical results and technical problems of transcatheter coil embolization for splenic artery aneurysm. Subjects were 16 patients (8 men, 8 women; age range, 40-80 years) who underwent transcatheter embolization for splenic artery aneurysm (14 true aneurysms, 2 false aneurysms) at one of our hospitals during the period January 1997 through July 2005. Two aneurysms (12.5%) were diagnosed at the time of rupture. Multiple splenic aneurysms were found in seven patients. Aneurysms were classified by site as proximal (or strictly ostial) (n = 3), middle (n = 3), or hilar (n = 10). The indication for transcatheter arterial embolization was a false or true aneurysm 20 mm in diameter. Embolic materials were fibered coils and interlocking detachable coils. Embolization was performed by the isolation technique, the packing technique, or both. Technically, all aneurysms were devascularized without severe complications. Embolized aneurysms were 6-40 mm in diameter (mean, 25 mm). Overall, the primary technical success rate was 88% (14 of 16 patients). In the remaining 2 patients (12.5%), partial recanalization occurred, and re-embolization was performed. The secondary technical success rate was 100%. Seven (44%) of the 16 study patients suffered partial splenic infarction. Intrasplenic branching originating from the aneurysm was observed in five patients. We conclude that transcatheter coil embolization should be the initial treatment of choice for splenic artery aneurysm

  13. Stellarator Coil Design and Plasma Sensitivity

    International Nuclear Information System (INIS)

    Ku, Long-Poe; Boozer, Allen H.

    2010-01-01

    The rich information contained in the plasma response to external magnetic perturbations can be used to help design stellarator coils more effectively. We demonstrate the feasibility by first devel oping a simple, direct method to study perturbations in stellarators that do not break stellarator symmetry and periodicity. The method applies a small perturbation to the plasma boundary and evaluates the resulting perturbed free-boundary equilibrium to build up a sensitivity matrix for the important physics attributes of the underlying configuration. Using this sensitivity information, design methods for better stellarator coils are then developed. The procedure and a proof-of-principle application are given that (1) determine the spatial distributions of external normal magnetic field at the location of the unperturbed plasma boundary to which the plasma properties are most sen- sitive, (2) determine the distributions of external normal magnetic field that can be produced most efficiently by distant coils, (3) choose the ratios of the magnitudes of the the efficiently produced magnetic distributions so the sensitive plasma properties can be controlled. Using these methods, sets of modular coils are found for the National Compact Stellarator Experiment (NCSX) that are either smoother or can be located much farther from the plasma boundary than those of the present design.

  14. High-field superconducting nested coil magnet

    Science.gov (United States)

    Laverick, C.; Lobell, G. M.

    1970-01-01

    Superconducting magnet, employed in conjunction with five types of superconducting cables in a nested solenoid configuration, produces total, central magnetic field strengths approaching 70 kG. The multiple coils permit maximum information on cable characteristics to be gathered from one test.

  15. Coil in bottom part of splitter magnet

    CERN Multimedia

    CERN PhotoLab

    1976-01-01

    Radiation-resistant coil being bedded into the bottom part of a splitter magnet. This very particular magnet split the beam into 3 branches, for 3 target stations in the West-Area. See Annual Report 1975, p.176, Figs.14 and 15.

  16. FRC translation into a compression coil

    International Nuclear Information System (INIS)

    Chrien, R.E.

    1986-01-01

    The equilibrium and translational kinematics of Field-Reversed Configurations (FRCs) in a cylindrical coil which does not conserve flux are problems that arise in connection with adiabatic compressional heating. In this paper, they consider several features of the problem of FRC translation into a compression coil. First, the magnitude of the guide field is calculated and found to exceed that which would be applied to a flux conserver. Second, energy conservation is applied to FRC translation from a flux conserver into a compression coil. It is found that a significant temperature decrease is required for translation to be energetically possible. The temperature change depends on the external inductance in the compression circuit. An analogous case is that of a compression region composed of a compound magnet; in this case the temperature change depends on the ratio of inner and outer coil radii. Finally, the kinematics of intermediate translation states are calculated using an abrupt transition model. It is found, in this model, that the FRC must overcome a potential hill during translation, which requires a small initial velocity

  17. Traveling-wave synchronous coil gun

    International Nuclear Information System (INIS)

    Elliott, D.G.

    1991-01-01

    This paper reports on a traveling-wave synchronous coil gun which permits independent adjustment of the magnetic field and armature current for high velocity at low armature mass fraction. Magnetic field energy is transferred from the rear of the wave to the front without passing through the power supply. Elaborate switching is required

  18. Structural design of the superconducting toroidal field coils for ITER

    International Nuclear Information System (INIS)

    Wong, F.M.G.; Sborchia, C.; Thome, R.J.; Malkov, A.; Titus, P.H.

    1995-01-01

    Structural design issues and features of the superconducting toroidal field (TF) coils for the International Thermonuclear Experimental Reactor (ITER) will be discussed. Selected analyses of the structural and mechanical behavior of the ITER TF coils will also be presented. (orig.)

  19. Hybrid equilibrium field coils for the ORNL TNS

    International Nuclear Information System (INIS)

    Peng, Y.K.M.; Strickler, D.J; Dory, R.A.

    1977-01-01

    In this study, we make a comparative study of the power supplies required by interior and exterior [to the toroidal field (TF) coils] equilibrium field coils that are separately appropriate for high-β, D-shaped plasmas in TNS. It is shown that the interior coils need power supplies that are an order of magnitude below those required by the exterior coils (while the latter case is much less difficult to build than the former). A hybrid EF coil concept is proposed that combines the interior and the exterior coils to retain their advantages in avoiding large interior coils while lowering the power supplied to the exterior coils by an order of magnitude

  20. Testing of the European LCT coil in the TOSKA facility

    International Nuclear Information System (INIS)

    Herz, W.; Katheder, H.; Krauth, H.

    1985-01-01

    The EURATOM-LCT coil was tested as a single coil in TOSKA. Load cells were mounted in the support structure to monitor forces between coil and vacuum vessel during cooldown and coil charging. Disturbances of components by magnetic fringing fields were carefully considered. To investigate the mechanical behaviour and compare it with FEM-calculations the coil was equipped with strain gauge rosettes and displacement transducers. Van Mises stresses in the coil case are in agreement with calculations. As known from special investigations during coil manufacturing the average radial Young modulus varies along the periphery caused by the different curvatures. This leads to differences with FEM-calculation (larger gaps between winding and coil case) assuming a larger constant Young modulus performed at the beginning of the project

  1. A history of detachable coils: 1987-2012.

    Science.gov (United States)

    Hui, Ferdinand K; Fiorella, David; Masaryk, Thomas J; Rasmussen, Peter A; Dion, Jacques E

    2014-03-01

    The development of detachable coils is one of the most pivotal developments in neurointervention, providing a tool that could be used to treat a wide variety of hemorrhagic stroke. From the original Guglielmi detachable coil, a number of different coil designs and delivery designs have evolved. This article reviews the history of commercially available detachable coils. A timeline of detachable coils was constructed and coil design philosophies were reviewed. A complete list of commercially available coils is presented in a timeline format. Detachable coil technology continues to evolve. Advances in construction and design have yielded products which may benefit patients in terms of safety, radiation dose reduction and cost of treatment. Continued evolution is expected, irrespective of competing disruptive technologies.

  2. Superconducting coil design for a tokamak experimental power reactor

    International Nuclear Information System (INIS)

    Turner, L.R.; Wang, S.T.; Smelser, P.

    1977-01-01

    Superconducting toroidal field (TF) and polodial-field (PF) coils have been designed for the proposed Argonne National Laboratory experimental power reactor (EPR). Features of the design include: (1) Peak field of 8 T at 4.2 K or 10 T at 3.0 K. (2) Constant-tension shape for the TF coils, corrected for the finite number (16) of coils. (3) Analysis of errors in coil alignment. (4) Comparison of safety aspects of series-connected and parallel-connected coils. (5) A 60 kA sheet conductor of NbTi with copper stabilizer and stainless steel for support. (6) Superconducting PF coils outside the TF coils. (7) The TF coils shielded from pulsed fields by high-purity aluminum

  3. Mechanical design of a high field common coil magnet

    CERN Document Server

    Caspi, S; Dietderich, D R; Gourlay, S A; Gupta, R; McInturff, A; Millos, G; Scanlan, R M

    1999-01-01

    A common coil design for high field 2-in-1 accelerator magnets has been previously presented as a "conductor-friendly" option for high field magnets applicable for a Very Large Hadron Collider. This paper presents the mechanical design for a 14 tesla 2-in-1 dipole based on the common coil design approach. The magnet will use a high current density Nb/sub 3/Sn conductor. The design addresses mechanical issues particular to the common coil geometry: horizontal support against coil edges, vertical preload on coil faces, end loading and support, and coil stresses and strains. The magnet is the second in a series of racetrack coil magnets that will provide experimental verification of the common coil design approach. (9 refs).

  4. Testing electrical insulation of LCT coils and instrumentation

    International Nuclear Information System (INIS)

    Luton, J.N.; Ulbricht, A.R.; Ellis, J.F.; Shen, S.S.; Wilson, C.T.; Okuno, K.; Siewerdt, L.O.; Zahn, G.R.; Zichy, J.A.

    1986-09-01

    Three of the superconducting test coils in the Large Coil Task (LCT) use conductors cooled internally by forced flow of helium. In the other three coils, the conductors are cooled externally by a bath of helium. The coils and facility are designed for rapid discharges (dumps) at voltages up to 2.5 kV, depending on coil design. Many coil sensors are connected electrically to the conductors. These sensor leads and signal conditioning equipment also experience high voltage. High-potential tests of ground insulation were performed on all components of the International Fusion Superconducting Magnet Test Facility (IFSMTF). Coil insulation was also tested by ring-down tests that produced voltage distributions within the coils like those occurring during rapid discharge. Methods were developed to localize problem areas and to eliminate them. The effect on breakdown voltage near the Paschen minimum of magnetic fields up to 2 T was investigated

  5. High-resolution MR imaging of triangular fibrocartilage complex (TFCC): comparison of microscopy coils and a conventional small surface coil

    Energy Technology Data Exchange (ETDEWEB)

    Yoshioka, Hiroshi [Department of Radiology, University of Tsukuba, Tsukuba (Japan); Department of Radiology, Brigham and Women' s Hospital, 75 Francis Street, 02115, Boston, MA (United States); Ueno, Teruko; Itai, Yuji [Department of Radiology, University of Tsukuba, Tsukuba (Japan); Tanaka, Toshikazu [Department of Orthopedic Surgery, Tsukuba Kinen Hospital, Tsukuba (Japan); Shindo, Masashi [Tsukuba University Hospital, Tsukuba (Japan)

    2003-10-01

    To compare MR images of the triangular fibrocartilage complex (TFCC) using microscopy coils with those using a conventional surface coil qualitatively and quantitatively. Proton density-weighted images and T2*-weighted images of the TFCC from ten normal volunteers were obtained with a conventional surface coil (C4 coil; 80 mm in diameter), a 47-mm microscopy surface coil and a 23-mm microscopy surface coil at 1.5 T. Qualitative image analysis of MR images with three coils was performed by two radiologists who assigned one of five numerical scores (0, nonvisualization; 1, poor; 2, average; 3, good; 4, excellent) for five TFCC components, which were disc proper, triangular ligament, meniscus homologue, ulnotriquetral and ulnolunate ligament. Quantitative analysis included the signal-to-noise ratio (S/N) of the disc proper of TFCC, the lunate cartilage, the lunate bone and the contrast-noise-ratio (C/N) between articular cartilage and disc proper or bone marrow were measured. All structures show higher scores qualitatively on MR with microscopy coils than those with a C4 coil, and the difference was significant with the exception of the ulnolunate ligament. MR with microscopy coils showed significantly higher S/N values than those with a conventional surface coil (P<0.05 to P<0.001). T2*-weighted images using microscopy coils showed significantly higher cartilage-disc proper C/N and cartilage-bone marrow C/N (P<0.01 to P<0.001). On proton density-weighted images, the C/N between cartilage and disc proper with two microscopy coils was significantly higher (P<0.01) than that with a conventional coil. High-resolution MR images of the normal wrist using microscopy coils were superior to those using a conventional surface coil qualitatively and quantitatively. High-resolution MR imaging with a microscopy coil would be a promising method to diagnose TFCC lesions. (orig.)

  6. Dryout in sodium-heated helically-coiled steam generator tubes

    International Nuclear Information System (INIS)

    Tomita, Y.; Kosugi, T.; Kubota, J.; Nakajima, K.; Tsuchiya, T.

    1984-01-01

    Experimental research on the dryout phenomenon in sodium heated, helically coiled steam generator tubes was carried out. The fluctuation of the tube wall temperature caused by dryout was measured with thermocouples installed in the center of the tube wall. Empirical correlations of dryout quality were developed as functions of critical heat flux, water mass velocity and saturation pressure. These correlations confirmed that the design criterion of the MONJU steam generator was reasonable. (author)

  7. Electronic warfare receivers and receiving systems

    CERN Document Server

    Poisel, Richard A

    2014-01-01

    Receivers systems are considered the core of electronic warfare (EW) intercept systems. Without them, the fundamental purpose of such systems is null and void. This book considers the major elements that make up receiver systems and the receivers that go in them.This resource provides system design engineers with techniques for design and development of EW receivers for modern modulations (spread spectrum) in addition to receivers for older, common modulation formats. Each major module in these receivers is considered in detail. Design information is included as well as performance tradeoffs o

  8. GBNV encoded movement protein (NSm) remodels ER network via C-terminal coiled coil domain

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Pratibha; Savithri, H.S., E-mail: bchss@biochem.iisc.ernet.in

    2015-08-15

    Plant viruses exploit the host machinery for targeting the viral genome–movement protein complex to plasmodesmata (PD). The mechanism by which the non-structural protein m (NSm) of Groundnut bud necrosis virus (GBNV) is targeted to PD was investigated using Agrobacterium mediated transient expression of NSm and its fusion proteins in Nicotiana benthamiana. GFP:NSm formed punctuate structures that colocalized with mCherry:plasmodesmata localized protein 1a (PDLP 1a) confirming that GBNV NSm localizes to PD. Unlike in other movement proteins, the C-terminal coiled coil domain of GBNV NSm was shown to be involved in the localization of NSm to PD, as deletion of this domain resulted in the cytoplasmic localization of NSm. Treatment with Brefeldin A demonstrated the role of ER in targeting GFP NSm to PD. Furthermore, mCherry:NSm co-localized with ER–GFP (endoplasmic reticulum targeting peptide (HDEL peptide fused with GFP). Co-expression of NSm with ER–GFP showed that the ER-network was transformed into vesicles indicating that NSm interacts with ER and remodels it. Mutations in the conserved hydrophobic region of NSm (residues 130–138) did not abolish the formation of vesicles. Additionally, the conserved prolines at positions 140 and 142 were found to be essential for targeting the vesicles to the cell membrane. Further, systematic deletion of amino acid residues from N- and C-terminus demonstrated that N-terminal 203 amino acids are dispensable for the vesicle formation. On the other hand, the C-terminal coiled coil domain when expressed alone could also form vesicles. These results suggest that GBNV NSm remodels the ER network by forming vesicles via its interaction through the C-terminal coiled coil domain. Interestingly, NSm interacts with NP in vitro and coexpression of these two proteins in planta resulted in the relocalization of NP to PD and this relocalization was abolished when the N-terminal unfolded region of NSm was deleted. Thus, the NSm

  9. Compressing DNA sequence databases with coil

    Directory of Open Access Journals (Sweden)

    Hendy Michael D

    2008-05-01

    Full Text Available Abstract Background Publicly available DNA sequence databases such as GenBank are large, and are growing at an exponential rate. The sheer volume of data being dealt with presents serious storage and data communications problems. Currently, sequence data is usually kept in large "flat files," which are then compressed using standard Lempel-Ziv (gzip compression – an approach which rarely achieves good compression ratios. While much research has been done on compressing individual DNA sequences, surprisingly little has focused on the compression of entire databases of such sequences. In this study we introduce the sequence database compression software coil. Results We have designed and implemented a portable software package, coil, for compressing and decompressing DNA sequence databases based on the idea of edit-tree coding. coil is geared towards achieving high compression ratios at the expense of execution time and memory usage during compression – the compression time represents a "one-off investment" whose cost is quickly amortised if the resulting compressed file is transmitted many times. Decompression requires little memory and is extremely fast. We demonstrate a 5% improvement in compression ratio over state-of-the-art general-purpose compression tools for a large GenBank database file containing Expressed Sequence Tag (EST data. Finally, coil can efficiently encode incremental additions to a sequence database. Conclusion coil presents a compelling alternative to conventional compression of flat files for the storage and distribution of DNA sequence databases having a narrow distribution of sequence lengths, such as EST data. Increasing compression levels for databases having a wide distribution of sequence lengths is a direction for future work.

  10. Trends in tungsten coil atomic spectrometry

    Science.gov (United States)

    Donati, George L.

    Renewed interest in electrothermal atomic spectrometric methods based on tungsten coil atomizers is a consequence of a world wide increasing demand for fast, inexpensive, sensitive, and portable analytical methods for trace analysis. In this work, tungsten coil atomic absorption spectrometry (WCAAS) and tungsten coil atomic emission spectrometry (WCAES) are used to determine several different metals and even a non-metal at low levels in different samples. Improvements in instrumentation and new strategies to reduce matrix effects and background signals are presented. Investigation of the main factors affecting both WCAAS and WCAES analytical signals points to the importance of a reducing, high temperature gas phase in the processes leading to atomic cloud generation. Some more refractory elements such as V and Ti were determined for the first time by double tungsten coil atomic emission spectrometry (DWCAES). The higher temperatures provided by two atomizers in DWCAES also allowed the detection of Ag, Cu and Sn emission signals for the first time. Simultaneous determination of several elements by WCAES in relatively complex sample matrices was possible after a simple acid extraction. The results show the potential of this method as an alternative to more traditional, expensive methods for fast, more effective analyses and applications in the field. The development of a new metallic atomization cell is also presented. Lower limits of detection in both WCAAS and WCAES determinations were obtained due to factors such as better control of background signal, smaller, more isothermal system, with atomic cloud concentration at the optical path for a longer period of time. Tungsten coil-based methods are especially well suited to applications requiring low sample volume, low cost, sensitivity and portability. Both WCAAS and WCAES have great commercial potential in fields as diverse as archeology and industrial quality control. They are simple, inexpensive, effective

  11. Superconductive magnet having shim coils and quench protection circuits

    International Nuclear Information System (INIS)

    Schwall, R.E.

    1987-01-01

    A superconductive magnet is described comprising: a first persistent current loop comprising a first superconductor and a main coil connected to the first superconductor, the main coil being operative in response to superconduction therein to generate a primary magnetic field; a second persistent current loop comprising a second superconductor and a shim coil connected thereto, the shim coil being operative in response to superconduction therein to generate a corrective field for correcting aberrations in a predetermined gradient in the primary magnetic field, the shim coil having fewer turns than the main coil and being inductively coupled therewith whereby small changes in the current in the main coil cause much greater changes in the current in the shim coil. The magnet is characterized by an improvement which consists of: a first heater connected across the second persistent loop in parallel with the shim coil, the first heater being normally inoperative to carry current while the shim coil and the second superconductor are superconducting, the first heater being operative in response to current therein to heat the shim coil to a resistive state; and protective circuit means comprising a second heater connected to the main coil for carrying current from the main coil upon quenching of the main coil, the second heater being disposed in thermal contact with the second superconductor to heat the second superconductor to a resistive state in response to the current from the main coil to thereby divert current in the second persistent loop through the second heater causing it to heat the shim coil to a resistive state and resistively dissipate energy therein

  12. Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif.

    Directory of Open Access Journals (Sweden)

    Nora Céspedes

    Full Text Available Protein α-helical coiled coil structures that elicit antibody responses, which block critical functions of medically important microorganisms, represent a means for vaccine development. By using bioinformatics algorithms, a total of 50 antigens with α-helical coiled coil motifs orthologous to Plasmodium falciparum were identified in the P. vivax genome. The peptides identified in silico were chemically synthesized; circular dichroism studies indicated partial or high α-helical content. Antigenicity was evaluated using human sera samples from malaria-endemic areas of Colombia and Papua New Guinea. Eight of these fragments were selected and used to assess immunogenicity in BALB/c mice. ELISA assays indicated strong reactivity of serum samples from individuals residing in malaria-endemic regions and sera of immunized mice, with the α-helical coiled coil structures. In addition, ex vivo production of IFN-γ by murine mononuclear cells confirmed the immunogenicity of these structures and the presence of T-cell epitopes in the peptide sequences. Moreover, sera of mice immunized with four of the eight antigens recognized native proteins on blood-stage P. vivax parasites, and antigenic cross-reactivity with three of the peptides was observed when reacted with both the P. falciparum orthologous fragments and whole parasites. Results here point to the α-helical coiled coil peptides as possible P. vivax malaria vaccine candidates as were observed for P. falciparum. Fragments selected here warrant further study in humans and non-human primate models to assess their protective efficacy as single components or assembled as hybrid linear epitopes.

  13. Coiled-coil forming peptides for the induction of silver nanoparticles

    International Nuclear Information System (INIS)

    Božič Abram, Sabina; Aupič, Jana; Dražić, Goran; Gradišar, Helena; Jerala, Roman

    2016-01-01

    Biopolymers with defined sequence patterns offer an attractive alternative for the formation of silver nanoparticle (AgNP). A set of coiled-coil dimer forming peptides was tested for their AgNP formation ability. Seventeen of those peptides mediated the formation of AgNPs in aqueous solution at neutral pH, while the formation of a coiled-coil dimer inhibited the nanoparticle generation. A QSAR regression model on the relationship between sequence and function suggests that in this peptide type the patterns KXQQ and KXEE are favorable, whereas Ala residues appear to have an inhibitory effect. UV–VIS spectra of the obtained nanoparticles gave a peak at around 420 nm, typical for AgNPs in the size range around 40 nm, which was confirmed by dynamic light scattering and transmission electron microscopy. Peptide-induced AgNPs exhibited good antibacterial activity, even after a 15 min contact time, while they had low toxicity to human cells at the same concentrations. These results show that our designed peptides generate AgNPs with antibacterial activity at mild conditions and might be used for antibacterial coatings. - Highlights: • 17 of the 30 tested coiled-coil forming peptides induce AgNP formation. • Coiled-coil dimer formation suppresses AgNP generation of individual peptides. • Size of the peptide-induced silver nanoparticles is around 40 nm. • QSAR analysis points to the importance of KXQQ and KXEE motifs for AgNP generation. • Peptide-induced silver nanoparticles exhibit antibacterial activity.

  14. CCBuilder 2.0: Powerful and accessible coiled-coil modeling.

    Science.gov (United States)

    Wood, Christopher W; Woolfson, Derek N

    2018-01-01

    The increased availability of user-friendly and accessible computational tools for biomolecular modeling would expand the reach and application of biomolecular engineering and design. For protein modeling, one key challenge is to reduce the complexities of 3D protein folds to sets of parametric equations that nonetheless capture the salient features of these structures accurately. At present, this is possible for a subset of proteins, namely, repeat proteins. The α-helical coiled coil provides one such example, which represents ≈ 3-5% of all known protein-encoding regions of DNA. Coiled coils are bundles of α helices that can be described by a small set of structural parameters. Here we describe how this parametric description can be implemented in an easy-to-use web application, called CCBuilder 2.0, for modeling and optimizing both α-helical coiled coils and polyproline-based collagen triple helices. This has many applications from providing models to aid molecular replacement for X-ray crystallography, in silico model building and engineering of natural and designed protein assemblies, and through to the creation of completely de novo "dark matter" protein structures. CCBuilder 2.0 is available as a web-based application, the code for which is open-source and can be downloaded freely. http://coiledcoils.chm.bris.ac.uk/ccbuilder2. We have created CCBuilder 2.0, an easy to use web-based application that can model structures for a whole class of proteins, the α-helical coiled coil, which is estimated to account for 3-5% of all proteins in nature. CCBuilder 2.0 will be of use to a large number of protein scientists engaged in fundamental studies, such as protein structure determination, through to more-applied research including designing and engineering novel proteins that have potential applications in biotechnology. © 2017 The Authors Protein Science published by Wiley Periodicals, Inc. on behalf of The Protein Society.

  15. Coiled-coil forming peptides for the induction of silver nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Božič Abram, Sabina [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); Graduate School of Biomedicine, University of Ljubljana, Ljubljana 1000 (Slovenia); Aupič, Jana [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); Doctoral Programme in Chemical Sciences, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana 1000 (Slovenia); Dražić, Goran [Laboratory for Materials Chemistry, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); Gradišar, Helena [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); EN-FIST, Centre of Excellence, Trg Osvobodilne fronte 13, Ljubljana 1000 (Slovenia); Jerala, Roman, E-mail: roman.jerala@ki.si [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); EN-FIST, Centre of Excellence, Trg Osvobodilne fronte 13, Ljubljana 1000 (Slovenia)

    2016-04-08

    Biopolymers with defined sequence patterns offer an attractive alternative for the formation of silver nanoparticle (AgNP). A set of coiled-coil dimer forming peptides was tested for their AgNP formation ability. Seventeen of those peptides mediated the formation of AgNPs in aqueous solution at neutral pH, while the formation of a coiled-coil dimer inhibited the nanoparticle generation. A QSAR regression model on the relationship between sequence and function suggests that in this peptide type the patterns KXQQ and KXEE are favorable, whereas Ala residues appear to have an inhibitory effect. UV–VIS spectra of the obtained nanoparticles gave a peak at around 420 nm, typical for AgNPs in the size range around 40 nm, which was confirmed by dynamic light scattering and transmission electron microscopy. Peptide-induced AgNPs exhibited good antibacterial activity, even after a 15 min contact time, while they had low toxicity to human cells at the same concentrations. These results show that our designed peptides generate AgNPs with antibacterial activity at mild conditions and might be used for antibacterial coatings. - Highlights: • 17 of the 30 tested coiled-coil forming peptides induce AgNP formation. • Coiled-coil dimer formation suppresses AgNP generation of individual peptides. • Size of the peptide-induced silver nanoparticles is around 40 nm. • QSAR analysis points to the importance of KXQQ and KXEE motifs for AgNP generation. • Peptide-induced silver nanoparticles exhibit antibacterial activity.

  16. Coiled coil peptides as universal linkers for the attachment of recombinant proteins to polymer therapeutics

    Czech Academy of Sciences Publication Activity Database

    Pechar, Michal; Pola, Robert; Laga, Richard; Ulbrich, Karel; Bednárová, Lucie; Maloň, Petr; Sieglová, Irena; Král, Vlastimil; Fábry, Milan; Vaněk, O.

    2011-01-01

    Roč. 12, č. 10 (2011), s. 3645-3655 ISSN 1525-7797 R&D Projects: GA ČR GA203/08/0543; GA MŠk 1M0505 Institutional research plan: CEZ:AV0Z40500505; CEZ:AV0Z40550506; CEZ:AV0Z50520514 Keywords : coiled coil * polymer the rapeutics * drug targeting Subject RIV: CC - Organic Chemistry Impact factor: 5.479, year: 2011

  17. Transport of one SC coil through the village of Meyrin

    CERN Multimedia

    1956-01-01

    The energizing coils of the Synchro-cyclotron magnet were manufactured in Belgium before travelling to Basel in Switzerland by boat and continuing by road to Geneva. The first coil reached Geneva in December 1955, with the second following in early 1956. The coils were stored in a hangar at the Geneva airport before they were brought to CERN in May 1956.

  18. Strain and stress of the ASDEX multipole magnetic coils

    International Nuclear Information System (INIS)

    Jandl, O.; Pillsticker, M.

    1978-01-01

    A brief description of the technical concept of the multipole magnetic field coils for the ASDEX tokamak is given. The various loads of the coils are explained in quality. To compute displacement and stress of the coils FEM computer programs are used. The computing models applied to this problem are founded and the results and the conclusions are reported. (orig.) [de

  19. Mechanical study of 20 MJ superconducting pulse coil

    International Nuclear Information System (INIS)

    Hattori, Yasuhide; Shimamoto, Susumu

    1985-09-01

    This paper describes calculation methods and computer codes of stress distribution in a circular-shaped superconducting pulsed coils. The stress problems of a large sized superconducting coil, for example, are discussed for 20 MJ pool-cooled pulse coil. Young's modulus of a stranded flat cable, low rigidity, is measured and evaluated. (author)

  20. Effects of Gradient Coil Noise and Gradient Coil Replacement on the Reproducibility of Resting State Networks.

    Science.gov (United States)

    Bagarinao, Epifanio; Tsuzuki, Erina; Yoshida, Yukina; Ozawa, Yohei; Kuzuya, Maki; Otani, Takashi; Koyama, Shuji; Isoda, Haruo; Watanabe, Hirohisa; Maesawa, Satoshi; Naganawa, Shinji; Sobue, Gen

    2018-01-01

    The stability of the MRI scanner throughout a given study is critical in minimizing hardware-induced variability in the acquired imaging data set. However, MRI scanners do malfunction at times, which could generate image artifacts and would require the replacement of a major component such as its gradient coil. In this article, we examined the effect of low intensity, randomly occurring hardware-related noise due to a faulty gradient coil on brain morphometric measures derived from T1-weighted images and resting state networks (RSNs) constructed from resting state functional MRI. We also introduced a method to detect and minimize the effect of the noise associated with a faulty gradient coil. Finally, we assessed the reproducibility of these morphometric measures and RSNs before and after gradient coil replacement. Our results showed that gradient coil noise, even at relatively low intensities, could introduce a large number of voxels exhibiting spurious significant connectivity changes in several RSNs. However, censoring the affected volumes during the analysis could minimize, if not completely eliminate, these spurious connectivity changes and could lead to reproducible RSNs even after gradient coil replacement.

  1. Strong contributions from vertical triads to helix-partner preferences in parallel coiled coils.

    Science.gov (United States)

    Steinkruger, Jay D; Bartlett, Gail J; Woolfson, Derek N; Gellman, Samuel H

    2012-09-26

    Pairing preferences in heterodimeric coiled coils are determined by complementarities among side chains that pack against one another at the helix-helix interface. However, relationships between dimer stability and interfacial residue identity are not fully understood. In the context of the "knobs-into-holes" (KIH) packing pattern, one can identify two classes of interactions between side chains from different helices: "lateral", in which a line connecting the adjacent side chains is perpendicular to the helix axes, and "vertical", in which the connecting line is parallel to the helix axes. We have previously analyzed vertical interactions in antiparallel coiled coils and found that one type of triad constellation (a'-a-a') exerts a strong effect on pairing preferences, while the other type of triad (d'-d-d') has relatively little impact on pairing tendencies. Here, we ask whether vertical interactions (d'-a-d') influence pairing in parallel coiled-coil dimers. Our results indicate that vertical interactions can exert a substantial impact on pairing specificity, and that the influence of the d'-a-d' triad depends on the lateral a' contact within the local KIH motif. Structure-informed bioinformatic analyses of protein sequences reveal trends consistent with the thermodynamic data derived from our experimental model system in suggesting that heterotriads involving Leu and Ile are preferred over homotriads involving Leu and Ile.

  2. Historical review: another 50th anniversary--new periodicities in coiled coils.

    Science.gov (United States)

    Gruber, Markus; Lupas, Andrei N

    2003-12-01

    In 1953, Francis Crick and Linus Pauling both proposed models of supercoiled alpha helices ('coiled coils') for the structure of keratin. These were the first attempts at modelling the tertiary structure of a protein. Crick emphasized the packing mode of the side-chains ('knobs-into-holes'), which required a periodicity of seven residues over two helical turns (7/2) and a supercoil in the opposite sense of the constituent helices. By contrast, Pauling envisaged a broader set of periodicities (4/1, 7/2, 18/5, 15/4, 11/3) and supercoils of both senses. Crick's model became canonical and the 'heptad repeat' essentially synonymous with coiled coils, but 50 years later new crystal structures and protein sequences show that the less common periodicities envisaged by Pauling also occur in coiled coils, adding a variant packing mode ('knobs-to-knobs') to the standard model. Pauling's laboratory notebooks suggest that he searched unsuccessfully for this packing mode in 1953.

  3. Coiled-Coil Proteins Facilitated the Functional Expansion of the Centrosome

    Science.gov (United States)

    Kuhn, Michael; Hyman, Anthony A.; Beyer, Andreas

    2014-01-01

    Repurposing existing proteins for new cellular functions is recognized as a main mechanism of evolutionary innovation, but its role in organelle evolution is unclear. Here, we explore the mechanisms that led to the evolution of the centrosome, an ancestral eukaryotic organelle that expanded its functional repertoire through the course of evolution. We developed a refined sequence alignment technique that is more sensitive to coiled coil proteins, which are abundant in the centrosome. For proteins with high coiled-coil content, our algorithm identified 17% more reciprocal best hits than BLAST. Analyzing 108 eukaryotic genomes, we traced the evolutionary history of centrosome proteins. In order to assess how these proteins formed the centrosome and adopted new functions, we computationally emulated evolution by iteratively removing the most recently evolved proteins from the centrosomal protein interaction network. Coiled-coil proteins that first appeared in the animal–fungi ancestor act as scaffolds and recruit ancestral eukaryotic proteins such as kinases and phosphatases to the centrosome. This process created a signaling hub that is crucial for multicellular development. Our results demonstrate how ancient proteins can be co-opted to different cellular localizations, thereby becoming involved in novel functions. PMID:24901223

  4. Inkjet Printed Planar Coil Antenna Analysis for NFC Technology Applications

    Directory of Open Access Journals (Sweden)

    I. Ortego

    2012-01-01

    Full Text Available The aim of this paper is to examine the potential of inkjet printing technology for the fabrication of Near Field Communication (NFC coil antennas. As inkjet printing technology enables deposition of a different number of layers, an accurate adjustment of the printed conductive tracks thickness is possible. As a consequence, input resistance and Q factor can be finely tuned as long as skin depth is not surpassed while keeping the same inductance levels. This allows the removal of the typical damping resistance present in current NFC inductors. A general methodology including design, simulation, fabrication, and measurement is presented for rectangular, planar-spiral inductors working at 13.56 MHz. Analytical formulas, computed numerical models, and measured results for antenna input impedance are compared. Reflection coefficient is designated as a figure of merit to analyze the correlation among them, which is found to be below −10 dB. The obtained results demonstrate the suitability of this technology in the fabrication of low cost, environmentally friendly NFC coils on flexible substrates.

  5. Characteristics analysis on a superconductor resonance coil WPT system according to cooling vessel materials in different distances

    International Nuclear Information System (INIS)

    Jeong, In-Sung; Lee, Yu-Kyeong; Choi, Hyo-Sang

    2016-01-01

    Highlights: • WPT using the superconductor coil was needed research for cooling vessel. FRP, bakelite, polystyrene, aluminum, and iron were applied as the cooling vessel material to analyze the WPT distance efficiency. • When the distance between the transmitter and receiver coils was 2000 mm, FRP being used for the cooling vessel made the transmission efficiency higher than any other materials. The efficiency and distance of sending power can be improved in the superconductor coil if the cooling vessel is made with FRP. - Abstract: The interest in wireless power transfer (WPT) that can send power without using wires has been increasing recently. Especially, there is a great interest in the wireless power devices for portable IT devices. The WPT devices that have been developed so far use the magnetic induction method, and they are not active due to their distance problem. A magnetic resonance WPT method was developed and has been actively researched to resolve this problem. A superconductor coil was applied in this study to increase the efficiency of the magnetic resonance WPT. FRP, bakelite, polystyrene, aluminum, and iron were applied as the cooling vessel material to analyze the WPT distance. The distance between the transmitter and receiver coils started from 800 mm and was increased by 200 mm. The reflection coefficient was measured at each distance. As a result, FRP, bakelite, plastic PVC, polystyrene of the reflection coefficient was similar. From among these FRP being used for the cooling vessel made the transmission characteristics higher than any other materials when the distance between the transmitter and receiver coils was 2,000 mm. On the other hand, the reflection coefficient dropped when iron was used. It is estimated based on the experimental results that the wireless power transmission characteristics and distance of sending power can be improved in the superconductor coil if the cooling vessel is made with FRP.

  6. Characteristics analysis on a superconductor resonance coil WPT system according to cooling vessel materials in different distances

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, In-Sung, E-mail: no21park@hanmail.net; Lee, Yu-Kyeong; Choi, Hyo-Sang, E-mail: hyosang@chosun.ac.kr

    2016-11-15

    Highlights: • WPT using the superconductor coil was needed research for cooling vessel. FRP, bakelite, polystyrene, aluminum, and iron were applied as the cooling vessel material to analyze the WPT distance efficiency. • When the distance between the transmitter and receiver coils was 2000 mm, FRP being used for the cooling vessel made the transmission efficiency higher than any other materials. The efficiency and distance of sending power can be improved in the superconductor coil if the cooling vessel is made with FRP. - Abstract: The interest in wireless power transfer (WPT) that can send power without using wires has been increasing recently. Especially, there is a great interest in the wireless power devices for portable IT devices. The WPT devices that have been developed so far use the magnetic induction method, and they are not active due to their distance problem. A magnetic resonance WPT method was developed and has been actively researched to resolve this problem. A superconductor coil was applied in this study to increase the efficiency of the magnetic resonance WPT. FRP, bakelite, polystyrene, aluminum, and iron were applied as the cooling vessel material to analyze the WPT distance. The distance between the transmitter and receiver coils started from 800 mm and was increased by 200 mm. The reflection coefficient was measured at each distance. As a result, FRP, bakelite, plastic PVC, polystyrene of the reflection coefficient was similar. From among these FRP being used for the cooling vessel made the transmission characteristics higher than any other materials when the distance between the transmitter and receiver coils was 2,000 mm. On the other hand, the reflection coefficient dropped when iron was used. It is estimated based on the experimental results that the wireless power transmission characteristics and distance of sending power can be improved in the superconductor coil if the cooling vessel is made with FRP.

  7. Omnidirectional Wireless Power Transfer System Based on Rotary Transmitting Coil for Household Appliances

    Directory of Open Access Journals (Sweden)

    Gongjun Liu

    2018-04-01

    Full Text Available An omnidirectional magnetically coupled resonant wireless power transfer (WPT system based on rotary transmitting coil is presented. The proposed scheme can ease the variations of the transfer efficiency and output power caused by the deviation of transfer direction, and improve the unbalanced power distribution phenomenon between the receivers, which are still not fully achieved in current WPT systems. The modified coupled-mode model is built first to describe the non-rotary multi-receiver WPT system. The analysis indicates that the transfer efficiency and output power of the system can be expressed as functions of the deviation angle between the transmitting coil and receiving coil, which has a non-negligible influence on the system performances. Then, the modified high order coupled-mode model containing time-varying parameters about the deviation angle is derived for the proposed omnidirectional WPT system. Theoretical analysis and simulated results indicate that this system can transfer power to multiple receivers around the transmitter synchronously and evenly, which is very suitable for wireless charging for household appliances indoors. The scheme feasibility and theoretical analysis are verified by experimental results.

  8. Tolerance Evaluation of Poloidal Shear Keys for ITER TF Coil

    International Nuclear Information System (INIS)

    Fu Youkun; Neil, M.; Cees Jong

    2006-01-01

    There are 18 ITER Toroidal Field (TF) Coils. Unlike the other ITER coils, these coils are structurally linked. These links consist of friction between the coil legs in the central vault formed by the inner straight legs of the coils, four outer inter-coil structures (OIS) and one inner inter-coil structure (IIS). The OIS consists essentially of bands around all 18 coils to provide shear support by forming shear panels with the coil case, and the IIS consists of poloidal circular keys placed directly between the coil cases. Global analysis of the 'perfect' coil shape has shown high stresses in the IIS, in the poloidal keyways. Optimization has successfully reduced these stresses to acceptable values as regards the expected fatigue resistance. However it is necessary to confirm that the stresses are still acceptable when realistic values of geometry variations are included (i.e. the effect of coil and case tolerances). Because of the extensive mechanical links between coils the poloidal key stresses can also be affected by tolerances elsewhere in the case. As the first step in assessment of the possible variations in stresses, a substructure technique is being used to develop a local model of the key region. The result of geometry variations between individual coils is a loss in the 18 fold symmetry used to simplify previous analyses. With the new and optimized model it should be possible to relax the 18-fold symmetry, but a full analysis of all 18 coils is still not possible. Systematic ways of representing the tolerance variation in the finite element model have been developed so that parametric studies can be undertaken without a full reconstruction of the model. (author)

  9. Unraveling double stranded alpha-helical coiled coils: an x-ray diffraction study on hard alpha-keratin fibers.

    Science.gov (United States)

    Kreplak, L; Doucet, J; Briki, F

    2001-04-15

    Transformations of proteins secondary and tertiary structures are generally studied in globular proteins in solution. In fibrous proteins, such as hard alpha-keratin, that contain long and well-defined double stranded alpha-helical coiled coil domains, such study can be directly done on the native fibrous tissue. In order to assess the structural behavior of the coiled coil domains under an axial mechanical stress, wide angle x-ray scattering and small angle x-ray scattering experiments have been carried out on stretched horse hair fibers at relative humidity around 30%. Our observations of the three major axial spacings as a function of the applied macroscopic strain have shown two rates. Up to 4% macroscopic strain the coiled coils were slightly distorted but retained their overall conformation. Above 4% the proportion of coiled coil domains progressively decreased. The main and new result of our study is the observation of the transition from alpha-helical coiled coils to disordered chains instead of the alpha-helical coiled coil to beta-sheet transition that occurs in wet fibers.

  10. Study on the performance improvement of the high temperature superconducting coil with several separated coils at the edges

    International Nuclear Information System (INIS)

    Ishiguri, S.; Oka, T.; Fukui, S.; Ogawa, J.; Sato, T.

    2008-01-01

    In designing high temperature superconducting (HTS) coils, it is important to secure large magnetic fields and stored energy using shorter tape length. Thus, it is necessary to improve the transport current performance of the coils. The critical current and n-value of an HTS tape depend on magnetic fields and flux angles under constant temperature. Considering these dependencies, we established a model to analyze coil critical current. This model clarifies that relatively large electric fields are generated at the coil edges. This adversely affects the transport current performance. In this study, the coil edge is separated into several coils, keeping the total tape length constant. This increases the coil critical current, stored energy, central magnetic field, and also the coil volume, which contains vacancies created by the separation. To estimate coil performance, we calculated the stored energy density, whose denominator is the increased coil volume. This stored energy density reaches its maximum value when the number of the separated coils is eight. At this optimum separation, the central magnetic field increases by 13%, and the stored energy improves by 43%, compared to a rectangular coil wound with the same tape length

  11. CCBuilder: an interactive web-based tool for building, designing and assessing coiled-coil protein assemblies.

    Science.gov (United States)

    Wood, Christopher W; Bruning, Marc; Ibarra, Amaurys Á; Bartlett, Gail J; Thomson, Andrew R; Sessions, Richard B; Brady, R Leo; Woolfson, Derek N

    2014-11-01

    The ability to accurately model protein structures at the atomistic level underpins efforts to understand protein folding, to engineer natural proteins predictably and to design proteins de novo. Homology-based methods are well established and produce impressive results. However, these are limited to structures presented by and resolved for natural proteins. Addressing this problem more widely and deriving truly ab initio models requires mathematical descriptions for protein folds; the means to decorate these with natural, engineered or de novo sequences; and methods to score the resulting models. We present CCBuilder, a web-based application that tackles the problem for a defined but large class of protein structure, the α-helical coiled coils. CCBuilder generates coiled-coil backbones, builds side chains onto these frameworks and provides a range of metrics to measure the quality of the models. Its straightforward graphical user interface provides broad functionality that allows users to build and assess models, in which helix geometry, coiled-coil architecture and topology and protein sequence can be varied rapidly. We demonstrate the utility of CCBuilder by assembling models for 653 coiled-coil structures from the PDB, which cover >96% of the known coiled-coil types, and by generating models for rarer and de novo coiled-coil structures. CCBuilder is freely available, without registration, at http://coiledcoils.chm.bris.ac.uk/app/cc_builder/. © The Author 2014. Published by Oxford University Press.

  12. Superconducting coil system and methods of assembling the same

    Science.gov (United States)

    Rajput-Ghoshal, Renuka; Rochford, James H.; Ghoshal, Probir K.

    2016-01-19

    A superconducting magnet apparatus is provided. The superconducting magnet apparatus includes a power source configured to generate a current; a first switch coupled in parallel to the power source; a second switch coupled in series to the power source; a coil coupled in parallel to the first switch and the second switch; and a passive quench protection device coupled to the coil and configured to by-pass the current around the coil and to decouple the coil from the power source when the coil experiences a quench.

  13. The IEA large coil task test results in IFSMTF

    International Nuclear Information System (INIS)

    Lubell, M.S.; Clinard, J.A.; Dresner, L.

    1987-01-01

    The Large Coil Task (LCT) is an international collaboration of the United States, EURATOM, Japan, and Switzerland to develop large superconducting magnets for fusion reactors. The testing phase of LCT was completed on September 3, 1987. All six coils exceeded the design goals, both as single coils and in six-coil toroidal tests. In addition, a symmetric torus test was performed in which a maximum field of 9 T was reached in all coils simultaneously. These are by far the largest magnets (either in size, weight, or stored energy) ever to achieve such a field. 6 refs., 6 figs., 3 tabs

  14. Random coil chemical shift for intrinsically disordered proteins

    DEFF Research Database (Denmark)

    Kjærgaard, Magnus; Brander, Søren; Poulsen, Flemming Martin

    2011-01-01

    . Temperature has a non-negligible effect on the (13)C random coil chemical shifts, so temperature coefficients are reported for the random coil chemical shifts to allow extrapolation to other temperatures. The pH dependence of the histidine random coil chemical shifts is investigated in a titration series......, which allows the accurate random coil chemical shifts to be obtained at any pH. By correcting the random coil chemical shifts for the effects of temperature and pH, systematic biases of the secondary chemical shifts are minimized, which will improve the reliability of detection of transient secondary...

  15. SSC [Superconducting Super Collider] dipole coil production tooling

    International Nuclear Information System (INIS)

    Carson, J.A.; Barczak, E.J.; Bossert, R.C.; Brandt, J.S.; Smith, G.A.

    1989-03-01

    Superconducting Super Collider dipole coils must be produced to high precision to ensure uniform prestress and even conductor distribution within the collared coil assembly. Tooling is being prepared at Fermilab for the production of high precision 1M and 16.6M SSC dipole coils suitable for mass production. The design and construction methods builds on the Tevatron tooling and production experience. Details of the design and construction methods and measured coil uniformity of 1M coils will be presented. 4 refs., 10 figs

  16. Tight aspect ratio tokamak power reactor with superconducting TF coils

    International Nuclear Information System (INIS)

    Nishio, S.; Tobita, K.; Konishi, S.; Ando, T.; Hiroki, S.; Kuroda, T.; Yamauchi, M.; Azumi, M.; Nagata, M.

    2003-01-01

    Tight aspect ratio tokamak power reactor with super-conducting toroidal field (TF) coils has been proposed. A center solenoid coil system and an inboard blanket were discarded. The key point was how to find the engineering design solution of the TF coil system with the high field and high current density. The coil system with the center post radius of less than 1 m can generate the maximum field of ∼ 20 T. This coil system causes a compact reactor concept, where the plasma major and minor radii of 3.75 m and 1.9 m, respectively and the fusion power of 1.8 GW. (author)

  17. Instrumentation and test of the Swiss LCT-coil

    International Nuclear Information System (INIS)

    Zichy, J.A.; Horvath, I.; Jakob, B.; Marinucci, C.; Vecsey, G.; Weymuth, P.; Zellweger, J.

    1985-01-01

    Just before Christmas 1983 the fabrication of the Swiss LCT-coil was finished. Tests at ambient temperature were performed on the factory site and after delivery in Oak Ridge. To avoid an undesirable delay of the rescheduled Partial-Array Test it was agreed to install the coil without its superconducting bus. In July 1984 the Swiss LCT-coil was successfully cooled down to LHe temperature together with the other two fully installed coils. Besides the cooling system, the instrumentation, measured parameters of the coil and some preliminary results obtained during the ongoing Partial-Array Test are presented

  18. An Autonomous Coil Alignment System for the Dynamic Wireless Charging of Electric Vehicles to Minimize Lateral Misalignment

    Directory of Open Access Journals (Sweden)

    Karam Hwang

    2017-03-01

    Full Text Available This paper proposes an autonomous coil alignment system (ACAS for electric vehicles (EVs with dynamic wireless charging (DWC to mitigate the reduction in received power caused by lateral misalignment between the source and load coils. The key component of the ACAS is a novel sensor coil design, which can detect the load coil’s left or right position relative to the source coil by observing the change in voltage phase. This allows the lateral misalignment to be estimated through the wireless power transfer (WPT system alone, which is a novel tracking method for vehicular applications. Once misalignment is detected, the vehicle’s lateral position is self-adjusted by an autonomous steering function. The feasibility of the overall operation of the ACAS was verified through simulation and experiments. In addition, an analysis based on experimental results was conducted, demonstrating that 26% more energy can be transferred during DWC with the ACAS, just by keeping the vehicle’s load coil aligned with the source coil.

  19. Femtosecond Photon-Counting Receiver

    Science.gov (United States)

    Krainak, Michael A.; Rambo, Timothy M.; Yang, Guangning; Lu, Wei; Numata, Kenji

    2016-01-01

    An optical correlation receiver is described that provides ultra-precise distance and/or time/pulse-width measurements even for weak (single photons) and short (femtosecond) optical signals. A new type of optical correlation receiver uses a fourth-order (intensity) interferometer to provide micron distance measurements even for weak (single photons) and short (femtosecond) optical signals. The optical correlator uses a low-noise-integrating detector that can resolve photon number. The correlation (range as a function of path delay) is calculated from the variance of the photon number of the difference of the optical signals on the two detectors. Our preliminary proof-of principle data (using a short-pulse diode laser transmitter) demonstrates tens of microns precision.

  20. Coil supporting device for a nuclear fusion device

    International Nuclear Information System (INIS)

    Kuno, Kazuo.

    1976-01-01

    Object: To reduce a thermal stress of a coil such as a magnetic limiter to minimize stress acting on a protective tube of the coil. Structure: A coil within a protective tube has its outer periphery surrounded and supported by a heat-resisting material such as ceramic at more than two positions suitably spaced lengthwise of a coil conductor, and heat insulating members are interposed between both sides of the coil and the protective tube so that it may be retained with respect to the width of the coil. Further, a heat-resisting resilient member is inserted in a clearance between an outer circumference and an inner circumference of the coil to allow a radial displacement of the coil. As a result, elongation of the coil due to thermal expansion may be escaped at the aforesaid two supports to reduce thermal stress of the coil and protective tube to support the coil within the protective tube in positively heat-resisting and insulating manner. (Kamimura, M.)

  1. Measurement of a Conduction Cooled Nb3Sn Racetrack Coil

    Science.gov (United States)

    Kim, HS; Kovacs, C.; Rochester, J.; Sumption, MD; Tomsic, M.; Peng, X.; Doll, D.

    2017-12-01

    Use of superconducting coils for wind turbines and electric aircraft is of interest because of the potential for high power density and weight reduction. Here we test a racetrack coil developed as a proof-of-concept for cryogen-free superconducting motors and generators. The coil was wound with 1209 m of 0.7-mm-diameter insulated tube-type Nb3Sn wire. The coil was epoxy-impregnated, instrumented, covered with numerous layers of aluminized mylar insulation, and inserted vertically into a dewar. The system was cooled to 4.2 K, and a few inches of liquid helium was allowed to collect at the bottom of the dewar but below the coil. The coil was cooled by conduction via copper cooling bars were attached to the coil but also were immersed in the liquid helium at their lower ends. Several current tests were performed on the coil, initially in voltage mode, and one run in current mode. The maximum coil Ic at 4.2 K was 480 A, generating 3.06 T at the surface of the coil. The coil met the design targets with a noticeable margin.

  2. Stress relaxation in SSC 50mm dipole coils

    International Nuclear Information System (INIS)

    Rogers, D.; Markley, F.

    1992-04-01

    We are measuring the stress relaxation of SSC 50mm outer coils with the goal of predicting how much of the coil prestress will be lost while the coils are warehoused between manufacture and cooldown. We manufacture 3 inch (76.2mm) long segments of coil with the same materials and techniques that have been used for prototype coils. We are running four simultaneous tests in an attempt to separate the contributions of the different coil materials. Test one is a completely insulated coil section where the insulation is the all polyamide system being tested at Brookhaven; test two is a wire stack insulated only with the normal Kapton overwrap; test three is a stack of bare cable; and test four is a completely insulated normal coil section. All, except for the bare cable, include the ground insulation. The insulated coil sections are carefully dried before loading and testing in order to eliminate stress changes due to varying moisture content. The temperature dependence of the stress relaxation is being studied separately. Three companion papers presented at this conference will be: (1) ''Temperature dependence of the viscoelastic properties of SSC coil insulation'' (2) ''Measurement of the elastic modulus of Kapton perpendicular to the plane of the film at room and cryogenic temperatures'' (3) ''Theoretical methods for creep and stress relaxation studies of SSC coil.''

  3. Eccentric figure-eight coils for transcranial magnetic stimulation.

    Science.gov (United States)

    Sekino, Masaki; Ohsaki, Hiroyuki; Takiyama, Yoshihiro; Yamamoto, Keita; Matsuzaki, Taiga; Yasumuro, Yoshihiro; Nishikawa, Atsushi; Maruo, Tomoyuki; Hosomi, Koichi; Saitoh, Youichi

    2015-01-01

    Previously we proposed an eccentric figure-eight coil that can cause threshold stimulation in the brain at lower driving currents. In this study, we performed numerical simulations and magnetic stimulations to healthy subjects for evaluating the advantages of the eccentric coil. The simulations were performed using a simplified spherical brain model and a realistic human brain model. We found that the eccentric coil required a driving current intensity of approximately 18% less than that required by the concentric coil to cause comparable eddy current densities within the brain. The eddy current localization of the eccentric coil was slightly higher than that of the concentric coil. A prototype eccentric coil was designed and fabricated. Instead of winding a wire around a bobbin, we cut eccentric-spiral slits on the insulator cases, and a wire was woven through the slits. The coils were used to deliver magnetic stimulation to healthy subjects; among our results, we found that the current slew rate corresponding to motor threshold values for the concentric and eccentric coils were 86 and 78 A/µs, respectively. The results indicate that the eccentric coil consistently requires a lower driving current to reach the motor threshold than the concentric coil. Future development of compact magnetic stimulators will enable the treatment of some intractable neurological diseases at home. © 2014 Wiley Periodicals, Inc.

  4. Coils in a fusion device and its fabrication method

    International Nuclear Information System (INIS)

    Maeda, Hideto; Moritani, Einoshin.

    1975-01-01

    Object: To provide a coil for nuclear fusion equipment, which coil has superior rigidity and strength and is separable into two sections and used for removing impurity ions from high temperature plasma such as heavy hydrogen and tritium. Structure: The coil according to the invention is manufactured by (1) a step of insulating horseshoe-shaped conductors one from another and bundling them into coil halves. (2) a step of assembling a flange on a coil case accommodating each coil half and hermetically welding a lid to each end of the coil half, (3) a step of evacuating the interior of each coil case, (4) a step of pouring a thermosetting resin into each evacuated coil case and hardening the resin, (5) a step of connecting the two coil halves with their ends not covered with resin held in abutting relation to each other, (6) a step of coupling coil case joint pieces to the joined portions and covering the joint pieces with a seal box and hermetically welding the box to the joint pieces, and (7) a step of pouring a thermosetting resin into each evacuated joint portion and hardening the resin. (Kamimura, M.)

  5. Performance of the Conduction-Cooled LDX Levitation Coil

    Science.gov (United States)

    Michael, P. C.; Schultz, J. H.; Smith, B. A.; Titus, P. H.; Radovinsky, A.; Zhukovsky, A.; Hwang, K. P.; Naumovich, G. J.; Camille, R. J.

    2004-06-01

    The Levitated Dipole Experiment (LDX) was developed to study plasma confinement in a dipole magnetic field. Plasma is confined in the magnetic field of a 680-kg Nb3Sn Floating Coil (F-coil) that is electromagnetically supported at the center of a 5-m diameter by 3-m tall vacuum chamber. The Levitation Coil (L-coil) is a 2800-turn, double pancake winding that supports the weight of the F-coil and controls its vertical position within the vacuum chamber. The use of high-temperature superconductor (HTS) Bi-2223 for the L-coil minimizes the electrical and cooling power needed for levitation. The L-coil winding pack and support plate are suspended within the L-coil cryostat and cooled by conduction to a single-stage cryocooler rated for 25-W heat load at approximately 20 K. The coil current leads consist of conduction-cooled copper running from room temperature to 80 K and a pair of commercially-available, 150-A HTS leads. An automatically filled liquid-nitrogen reservoir provides cooling for the coil's radiation shield and for the leads' 80-K heat stations. This paper discusses the L-coil system design and its observed cryogenic performance.

  6. Deep brain transcranial magnetic stimulation using variable "Halo coil" system

    Science.gov (United States)

    Meng, Y.; Hadimani, R. L.; Crowther, L. J.; Xu, Z.; Qu, J.; Jiles, D. C.

    2015-05-01

    Transcranial Magnetic Stimulation has the potential to treat various neurological disorders non-invasively and safely. The "Halo coil" configuration can stimulate deeper regions of the brain with lower surface to deep-brain field ratio compared to other coil configurations. The existing "Halo coil" configuration is fixed and is limited in varying the site of stimulation in the brain. We have developed a new system based on the current "Halo coil" design along with a graphical user interface system that enables the larger coil to rotate along the transverse plane. The new system can also enable vertical movement of larger coil. Thus, this adjustable "Halo coil" configuration can stimulate different regions of the brain by adjusting the position and orientation of the larger coil on the head. We have calculated magnetic and electric fields inside a MRI-derived heterogeneous head model for various positions and orientations of the coil. We have also investigated the mechanical and thermal stability of the adjustable "Halo coil" configuration for various positions and orientations of the coil to ensure safe operation of the system.

  7. Coil irrigation in sugar cane (Saccharum officinarum

    Directory of Open Access Journals (Sweden)

    Jesús Sánchez Gutiérrez

    2016-01-01

    Full Text Available This study was made at the Basic Seed Bank of the Local Sugar Cane Research Station for the Mideastern Cuba, based in Camaguey, on brown carbonate soil, between 2013 and 12014. Coil irrigation was applied to meet the water requirements for the crop, according to the edafoclimatic conditions and the different phenological phases it has. The Savo method was used to determine useful rain water. Adjustment and complementation of the irrigation program was based on indicators that characterize the exploitation scheme. The machine´s working parameters were determined to meet the water needs, and increase crop´s overall yields. The evaluations and results achieved have contributed to new proposals for management and operation of coil irrigation, and they are important to increase its efficiency.

  8. Superconductors for W VII-X coils

    International Nuclear Information System (INIS)

    Maurer, W.

    1987-01-01

    Superconductor concepts are discussed with respect to operational current, cooling and bending behavior, and ac losses. The encouraging results for NbTi superconducting technology are recalled. It is argued that the WVII-X stellarator modular superconducting coils can be built just as the modular Cu coils for WVII-AS. Special attention must be paid to the dB/dt allowed for the conductor. Shape and price depend on the means used to avoid ac losses. Formula to elucidate the main physical parameters influencing ac loss behavior of superconductors are given. Configurations investigated with respect to plasma behavior are compared. Masses to be cooled were estimated for two configurations. The estimated cooling power is of the order of 3kW

  9. Power conditioner for a coil-gun

    International Nuclear Information System (INIS)

    Zabar, Z.; Joshi, P.N.

    1987-01-01

    This paper describes a power conditioning scheme for introducing currents sequentially into a linear array of coils which form the barrel of a coil-gun. The projectile, a conducting cylindrical sleeve, is driven by the force exerted on it by a traveling magnetic wave-packet created by the barrel currents. Since the rate of energy transfer is proportional to the projectile velocity, it was convenient to divide the barrel into three separate sections. These correspond to the low, medium and high velocity parts of the projectile motion. Each section is excited by a different method, chosen to satisfy the need for most efficient usage of energy stored in the power supply capacitors. Experiments are described with a breadboard model that test the feasibility of the medium-velocity power conditioning scheme

  10. Design of a dynamic transcranial magnetic stimulation coil system.

    Science.gov (United States)

    Ge, Sheng; Jiang, Ruoli; Wang, Ruimin; Chen, Ji

    2014-08-01

    To study the brain activity at the whole-head range, transcranial magnetic stimulation (TMS) researchers need to investigate brain activity over the whole head at multiple locations. In the past, this has been accomplished with multiple single TMS coils that achieve quasi whole-head array stimulation. However, these designs have low resolution and are difficult to position and control over the skull. In this study, we propose a new dynamic whole-head TMS mesh coil system. This system was constructed using several sagittal and coronal directional wires. Using both simulation and real experimental data, we show that by varying the current direction and strength of each wire, this new coil system can form both circular coils or figure-eight coils that have the same features as traditional TMS coils. Further, our new system is superior to current coil systems because stimulation parameters such as size, type, location, and timing of stimulation can be dynamically controlled within a single experiment.

  11. Globally optimal superconducting magnets part II: symmetric MSE coil arrangement.

    Science.gov (United States)

    Tieng, Quang M; Vegh, Viktor; Brereton, Ian M

    2009-01-01

    A globally optimal superconducting magnet coil design procedure based on the Minimum Stored Energy (MSE) current density map is outlined. The method has the ability to arrange coils in a manner that generates a strong and homogeneous axial magnetic field over a predefined region, and ensures the stray field external to the assembly and peak magnetic field at the wires are in acceptable ranges. The outlined strategy of allocating coils within a given domain suggests that coils should be placed around the perimeter of the domain with adjacent coils possessing alternating winding directions for optimum performance. The underlying current density maps from which the coils themselves are derived are unique, and optimized to possess minimal stored energy. Therefore, the method produces magnet designs with the lowest possible overall stored energy. Optimal coil layouts are provided for unshielded and shielded short bore symmetric superconducting magnets.

  12. Eddy current testing probe with dual half-cylindrical coils

    Science.gov (United States)

    Bae, Byung-Hoon; Choi, Jung-Mi; Kim, Soo-Yong

    2000-02-01

    We have developed a new eddy current probe composed of a dual half-cylindrical (2HC) coil as an exciting coil and a sensing coil that is placed in the small gap of the 2HC coil. The 2HC coil induces a linear eddy current on the narrow region within the target medium. The magnitude of eddy current has a maximum peak with the narrow width, underneath the center of the exciting 2HC coil. Because of the linear eddy current, the probe can be used to detect not only the existence of a crack but also its direction in conducting materials. Using specimen with a machined crack, and varying the exciting frequency from 0.5 to 100 kHz, we investigated the relationships between the direction of crack and the output voltage of the sensing coil.

  13. New technique for wiring SSC superconducting sextupole corrector coils

    International Nuclear Information System (INIS)

    Leon, B.

    1985-01-01

    There exists in the electronics industry, a technology for the manufacture of printed circuit (PC) boards which is directly transferable into the creation of highly controlled coils, such as the SSC sextupole superconducting corrector coils. This technology, which uses a process of laying down insulated wire in highly controlled patterns has heretofore been confined exclusively to the manufacture of high density printed circuit (PC) boards, possibly due to an ignorance of its utility in the field of precision winding of coils. This ability to fix wires in a well defined location can be used to produce precision wound coils in a very cost-effective manner. These coils may be superior in quality to conventionally made coils. Before describing what can be created with this technology, it is necessary to take a look at this coil winding process, the MULTIWIRE process, and the industry which has utilized this technology

  14. A new technique for wiring SSC superconducting sextupole corrector coils

    International Nuclear Information System (INIS)

    Leon, B.

    1985-01-01

    There exists in the electronics industry, a technology for the manufacture of printed circuit (PC) boards which is directly transferable into the creation of highly controlled coils, such as the SSC sextupole superconducting corrector coils. This technology, which uses a process of laying down insulated wire in highly controlled patterns, has heretofore been confined excusively to the manufacture of high density printed circuit (PC) boards, possibly due to an ignorance of its utility in the field of precision winding of coils. This ability to fix wires in a well defined location can be used to produce precision wound coils in a very cost-effective manner. These coils may be superior in quality to conventionally made coils. Before describing what can be created with this technology, it is necessary to take a look at this coil winding process, the MULTIWIRE process, and the industry which has utilized this technology

  15. Manufacture and mechanical test of a TORE SUPRA model coil

    International Nuclear Information System (INIS)

    Aymar, R.; Claudet, G.; Disdier, F.; Hamelin, J.; Libeyre, P.; Mayaux, G.; Meuris, C.; Parain, J.; Torossian, A.

    1980-09-01

    Inside the qualifying test programme, supporting the Tore Supra Design, a reduced scale model of a Bsub(T) coil was fabricated by a large industrial firm. This model coil is provided with the same features as those retained for the complete magnet. Tests of this model coil have been carried out in such a way that most of stresses which will arise in Tore Supra windings are simulated; simultaneously its cryogenic supply is fully representative of the system retained for the complete machine. Operation of the model coil has been found highly stable; under the conditions of applied field and forces a coil transition could be triggered, by an electrical heater located inside the coil, only when the temperature of the superfluid helium bath was close to Tsub(lambda). Thus, design and manufacturing techniques have been qualified satisfactorily to proceed to the next step: fabrication of the superconducting Bsub(T) coils of Tore Supra

  16. Mechanical properties of ISABELLE superconducting coils

    International Nuclear Information System (INIS)

    Thompson, P.; Bertsche, A.; Fuhrmann, J.; Greene, A.; Grove, E.; Repeta, L.; Short, F.; Tannenbaum, M.; Wanderer, P.

    1981-01-01

    As a part of the manufacturing processes, several mechanical measurements are made on ISABELLE dipoles. These are done both to control the process and to provide information for the evaluation of the behavior of the completed magnets. This paper discusses the Young's Modulus (E = 1-3 x 10 6 psi), the thermal contraction of the coil assembly (ΔL/L = 290 +- 17 x 10 -5 at 77 0 K), and the loss of applied prestress with time

  17. Voice coil based scanning probe microscopy

    Czech Academy of Sciences Publication Activity Database

    Klapetek, P.; Valtr, M.; Duchoň, V.; Sobota, Jaroslav

    2012-01-01

    Roč. 7, č. 6 (2012), 332:1-7 ISSN 1931-7573 R&D Projects: GA MPO FR-TI1/241; GA AV ČR KAN311610701; GA MŠk ED0017/01/01 Institutional support: RVO:68081731 Keywords : SPM * Voice coil * Interferometry Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.524, year: 2012

  18. Plan for the large coil program

    International Nuclear Information System (INIS)

    Haubenreich, P.N.; Anderson, W.C.; Luton, J.N.; Thompson, P.B.

    1977-02-01

    This document has been prepared by the Large Coil Program (LCP) to make generally available the information that has been generated up to this point and to indicate the direction of future work. A summary of objectives, general strategy, and implementation of the LCP is given. Expanded descriptions are given of program content, technical requirements, selection of testing arrangements, tentative schedule and method of preliminary cost estimation

  19. LLNL high-field coil program

    International Nuclear Information System (INIS)

    Miller, J.R.

    1986-01-01

    An overview is presented of the LLNL High-Field Superconducting Magnet Development Program wherein the technology is being developed for producing fields in the range of 15 T and higher for both mirror and tokamak applications. Applications requiring less field will also benefit from this program. In addition, recent results on the thermomechanical performance of cable-in-conduit conductor systems are presented and their importance to high-field coil design discussed

  20. Tiny intracranial aneurysms: Endovascular treatment by coil embolisation or sole stent deployment

    International Nuclear Information System (INIS)

    Lu Jun; Liu Jiachun; Wang Lijun; Qi Peng; Wang Daming

    2012-01-01

    Purpose: Tiny intracranial aneurysms pose a significant therapeutic challenge for interventional neuroradiologists. The authors report their preliminary results of endovascular treatment of these aneurysms. Methods: Between January 2002 and December 2009, 52 tiny intracranial aneurysms (defined as ≤3 mm in maximum diameter) in 46 patients (22 men; mean age, 57.9 years) were treated by endosaccular coil embolisation or sole stent deployment in the parent artery. Of 52 aneurysms, 29 had ruptured and 23 remained unruptured. The initial angiographic results, procedural complications, and clinical outcomes were assessed at discharge. Imaging follow-up was performed with cerebral angiography. Results: One aneurysm coiling procedure failed because of unsuccessful micro-catheterization. Forty-three aneurysms were successfully coil embolized, of which complete occlusion was obtained in 14, subtotal occlusion in 18 and incomplete occlusion in 11. The other 8 aneurysms were treated by sole stent deployment in the parent artery. Procedural complications (2 intraprocedural ruptures and 3 thromboembolic events) occurred in 5 (9.6%) of 52 aneurysms, resulting in permanent morbidity in only 1 (2.2%, 1/46) patient. No rebleeding occurred during clinical follow-up (mean duration, 46.7 months). Of the 16 coiled aneurysms that receiving repetitive angiography, 6 initially completely and 3 subtotally occluded aneurysms remained unchanged, 4 initially subtotally and 3 incompletely occluded aneurysms progressed to total occlusion. Five sole stent deployed aneurysms received angiographic follow-up (mean duration, 10.0 months), of which 3 remained unchanged, 1 became smaller and 1 progressed to total occlusion. Conclusion: Endovascular treatment of tiny intracranial aneurysms is technical feasible and relatively safe. Coil embolisation seems to be effective in preventing early recanalisation, whereas sole stenting technique needs further investigation to determine its effectiveness.

  1. Electron Beam Curing of Coil Coatings

    Energy Technology Data Exchange (ETDEWEB)

    Morganstern, K. H. [Radiation Dynamics, Inc., Westbury, NY (United States)

    1969-12-15

    The application of electron accelerators for the rapid curing of coatings on coil processing of steel and aluminium appears to have many practical and economic advantages. This paper discusses this particular application, but in the general framework of electron beam application by industry. Although industry has investigated radiation application for two decades, there have been few applications to date. The reasons for this are discussed as well as the shift in attitude now taking place, indicating a more ready acceptance of radiation processing by industry. This shift is apparent particularly in the coatings field, where the benefits of radiation processing are quite evident. In order to pinpoint these benefits a specific coatings application - coil coating - has been chosen. A typical conventional coil coating line is discussed and compared to a line employing a radiation source. Specific engineering information on the types of electron accelerators suitable for this application; the relative economics of radiation vs. heat curing; and a number of other peripheral advantages of radiation are discussed. (author)

  2. Thermal analysis of track based coils

    Energy Technology Data Exchange (ETDEWEB)

    Davey, K [American MAGLEV, Inc., Edgewater, FL (United States); Zowarka, R [CEM, Austin, TX (United States)

    1996-12-31

    This document examines the temperature rise of coils embedded in a concrete matrix. The ultimate goal is to predict the steady state temperature of the coils subject to a repeated passage of vehicles at a regular interval. The primary concern is in maintaining a maximum temperature which is less than that which would compromise the integrity of the insulation used on the wires. Three techniques are used to examine the problem. First, an analytical approach is used to determine not only the immediate temperature rise of the wire material itself, but also a consevative estimate of the steady state temperature expected. Second, the equations are examined for a one dimensional transient profile of the temperature with time. Finally, a two dimensional steady state boundary element solution is employed to estimate the steady state temperature profile both within the coils and within the rail. In this two dimensional boundary element assessment, an iterative approach is employed to accurately model the heat transfer coefficient h which ultimately defines the steady state temperature. (orig.)

  3. Numerical dosimetry of transcranial magnetic stimulation coils

    Science.gov (United States)

    Crowther, Lawrence; Hadimani, Ravi; Jiles, David

    2014-03-01

    Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulation technique capable of stimulating neurons by means of electromagnetic induction. TMS can be used to map brain function and shows promise for the diagnosis and treatment of neurological and psychiatric disorders. Calculation of fields induced in the brain are necessary to accurately identify stimulated neural tissue during TMS. This allows the development of novel TMS coil designs capable of stimulating deeper brain regions and increasing the localization of stimulation that can be achieved. We have performed numerical calculations of magnetic and electric field with high-resolution anatomically realistic human head models to find these stimulated brain regions for a variety of proposed TMS coil designs. The realistic head models contain heterogeneous tissue structures and electrical conductivities, yielding superior results to those obtained from the simplified homogeneous head models that are commonly employed. The attenuation of electric field as a function of depth in the brain and the localization of stimulating field have been methodically investigated. In addition to providing a quantitative comparison of different TMS coil designs the variation of induced field between subjects has been investigated. We also show the differences in induced fields between adult, adolescent and child head models to preemptively identify potential safety issues in the application of pediatric TMS.

  4. Transcatheter coil embolisation of pulmonary arteriovenous malformations

    International Nuclear Information System (INIS)

    Wingen, M.; Guenther, R.W.

    2001-01-01

    Evaluation of technical success, complications and long-term results of transcatheter coil embolisation in pulmonary arteriovenous malformations (pAVMs). Material and Methods: Transcatheter embolisations of 46 pAVMs in 14 patients were analysed retrospectively, and, 5 years after treatment, the patients were interviewed by telefone concerning persistent symptoms and complications. Main symptoms before embolisation were dyspnoe (86%), hypoxaemia (100%), cerebral ischemia (21%), and hemoptysis (14%); 11 patients (79%) suffered from hereditary hemorrhagic telangiectasia. Results: Embolisation with an average of 3,9 coils (min. 1, max. 19 coils) per pAVM yielded technical success in all cases. Only two minor complications, transitory pleuritis and a small lung infarction were observed. On follow up examination after 5 years either no residual complaints or substantial improvement of dyspnoe were reported; no patient suffered from neurologic or hemorrhagic complications after the embolisation. Conclusion: Transcatheter embolisation is a safe and minimally invasive therapy for pAVMs and has rightfully replaced surgical resection as the therapy of choice. (orig.) [de

  5. Single coil bistable, bidirectional micromechanical actuator

    Science.gov (United States)

    Tabat, Ned; Guckel, Henry

    1998-09-15

    Micromechanical actuators capable of bidirectional and bistable operation can be formed on substrates using lithographic processing techniques. Bistable operation of the microactuator is obtained using a single coil and a magnetic core with a gap. A plunger having two magnetic heads is supported for back and forth linear movement with respect to the gap in the magnetic core, and is spring biased to a neutral position in which the two heads are on each side of the gap in the core. The single electrical coil is coupled to the core and is provided with electrical current to attract one of the heads toward the core by reluctance action to drive the plunger to a limit of travel in one direction. The current is then cut off and the plunger returns by spring action toward the gap, whereafter the current is reapplied to the coil to attract the other head of the plunger by reluctance action to drive the plunger to its other limit of travel. This process can be repeated at a time when switching of the actuator is required.

  6. Quench simulation of SMES consisting of some superconducting coils

    International Nuclear Information System (INIS)

    Noguchi, S.; Oga, Y.; Igarashi, H.

    2011-01-01

    A chain of quenches may be caused by a quench of one element coil when SMES is consists of many element coils. To avoid the chain of quenches, the energy stored in element coil has to be quickly discharged. The cause of the chain of the quenches is the short time constant of the decreasing current of the quenched coil. In recent years, many HTS superconducting magnetic energy storage (HTS-SMES) systems are investigated and designed. They usually consist of some superconducting element coils due to storing excessively high energy. If one of them was quenched, the storage energy of the superconducting element coil quenched has to be immediately dispersed to protect the HTS-SMES system. As the result, the current of the other element coils, which do not reach to quench, increases since the magnetic coupling between the quenched element coil and the others are excessively strong. The increase of the current may cause the quench of the other element coils. If the energy dispersion of the element coil quenched was failed, the other superconducting element coil would be quenched in series. Therefore, it is necessary to investigate the behavior of the HTS-SMES after quenching one or more element coils. To protect a chain of quenches, it is also important to investigate the time constant of the coils. We have developed a simulation code to investigate the behavior of the HTS-SMES. By the quench simulation, it is indicated that a chain of quenches is caused by a quench of one element coil.

  7. Efficacy of deep rTMS for neuropathic pain in the lower limb: a randomized, double-blind crossover trial of an H-coil and figure-8 coil.

    Science.gov (United States)

    Shimizu, Takeshi; Hosomi, Koichi; Maruo, Tomoyuki; Goto, Yuko; Yokoe, Masaru; Kageyama, Yu; Shimokawa, Toshio; Yoshimine, Toshiki; Saitoh, Youichi

    2017-11-01

    OBJECTIVE Electrical motor cortex stimulation can relieve neuropathic pain (NP), but its use requires patients to undergo an invasive procedure. Repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex (M1) using a figure-8 coil can relieve NP noninvasively, but its ability to relieve lower limb pain is still limited. Deep rTMS using an H-coil can effectively stimulate deep brain regions and has been widely used for the treatment of various neurological diseases; however, there have been no clinical studies comparing the effectiveness of figure-8 coils and H-coils. This study assessed the clinical effectiveness of 5 once-daily stimulations with H-coils and figure-8 coils in patients with NP. METHODS This randomized, double-blind, 3-way crossover trial examined 18 patients with NP who sequentially received 3 types of stimulations in the M1 for 5 consecutive days; each 5-day stimulation period was followed by a 17-day follow-up period before crossing over to the next type of stimulation. During each rTMS session, patients received a 5-Hz rTMS to the M1 region corresponding to the painful lower limb. The visual analog scale (VAS) and the Japanese version of the short-form McGill Pain Questionnaire 2 (SF-MPQ2-J) were used to measure pain intensity. The primary outcome was VAS score reduction immediately after and 1 hour after intervention. RESULTS Both the VAS and SF-MPQ2-J showed significant pain improvement immediately after deep rTMS with an H-coil as compared with the sham group (p H-coil (p = 0.004) but not 1 hour after rTMS using a figure-8 coil. None of the patients exhibited any serious adverse events. CONCLUSIONS The current findings suggest that the use of deep rTMS with an H-coil in the lower limb region of the M1 in patients with NP was tolerable and could provide significant short-term pain relief. Clinical trial registration no.: UMIN000010536 ( http://www.umin.ac.jp/ctr/ ).

  8. Magnetic resonance imaging of the inner ear by using a hybrid radiofrequency coil at 7 T

    Science.gov (United States)

    Kim, Kyoung-Nam; Heo, Phil; Kim, Young-Bo; Han, Gyu-Cheol

    2015-01-01

    Visualization of the membranous structures of the inner ear has been limited to the detection of the normal fluid signal intensity within the bony labyrinth by using magnetic resonance imaging (MRI) equipped with a 1.5 Tesla (T) magnet. High-field (HF) MRI has been available for more than a decade, and numerous studies have documented its significant advantages over conventional MRI with regards to its use in basic scientific research and routine clinical assessments. No previous studies of the inner ear by using HF MRI have been reported, in part because high-quality resolution of mastoid pneumatization is challenging due to artifacts generated in the HF environment and insufficient performance of radiofrequency (RF) coils. Therefore, a hybrid RF coil with integrated circuitry was developed at 7 T and was targeted for anatomical imaging to achieve a high resolution image of the structure of the human inner ear, excluding the bony portion. The inner-ear's structure is composed of soft tissues containing hydrogen ions and includes the membranous labyrinth, endolymphatic space, perilymphatic space, and cochlear-vestibular nerves. Visualization of the inner-ear's anatomy was performed in-vivo with a custom-designed hybrid RF coil and a specific imaging protocol based on an interpolated breath-held examination sequence. The comparative signal intensity value at 30-mm away from the phantom side was 88% higher for the hybrid RF coil and 24% higher for the 8-channel transmit/receive (Tx/Rx) coil than for the commercial birdcage coil. The optimized MRI protocol employed a hybrid RF coil because it enabled high-resolution imaging of the inner-ear's anatomy and accurate mapping of structures including the cochlea and the semicircular canals. These results indicate that 7 T MRI achieves high spatial resolution visualization of the inner-ear's anatomy. Therefore, MRI imaging using a hybrid RF coil at 7 T could provide a powerful tool for clinical investigations of petrous

  9. Initial results of 3-dimensional 1H-magnetic resonance spectroscopic imaging in the localization of prostate cancer at 3 Tesla: should we use an endorectal coil?

    Science.gov (United States)

    Yakar, Derya; Heijmink, Stijn W T P J; Hulsbergen-van de Kaa, Christina A; Huisman, Henkjan; Barentsz, Jelle O; Fütterer, Jurgen J; Scheenen, Tom W J

    2011-05-01

    The purpose of this study was to compare the diagnostic performance of 3 Tesla, 3-dimensional (3D) magnetic resonance spectroscopic imaging (MRSI) in the localization of prostate cancer (PCa) with and without the use of an endorectal coil (ERC). Our prospective study was approved by the institutional review board, and written informed consent was obtained from all patients. Between October 2004 and January 2006, 18 patients with histologically proven PCa on biopsy and scheduled for radical prostatectomy were included and underwent 3D-MRSI with and without an ERC. The prostate was divided into 14 regions of interest (ROIs). Four readers independently rated (on a 5-point scale) their confidence that cancer was present in each of these ROIs. These findings were correlated with whole-mount prostatectomy specimens. Areas under the receiver-operating characteristic curve were determined. A difference with a P Tesla slightly but significantly increased the localization performance compared with not using an ERC.

  10. Feasible approach of contactless power transfer technology combined with HTS coils based on electromagnetic resonance coupling

    International Nuclear Information System (INIS)

    Chang, Yoon Do; Yim, Seong Woo; Hwang, Si Dole

    2013-01-01

    The contactless power transfer (CPT) systems have been recently gaining popularity widely since it is an available option to realize the power delivery and storage with connector-free devices across a large air gap. Especially, the CPT with electromagnetic resonance coupling method is possible to exchange energy within 2 m efficiently. However, the power transfer efficiency of CPT in commercialized products has been limited because the impedance matching of coupled coils is sensitive. As a reasonable approach, we combined the CPT system with HTS wire technology and called as, superconducting contactless power transfer (SUCPT) system. Since the superconducting coils have an enough current density, the superconducting antenna and receiver coils at CPT system have a merit to deliver and receive a mass amount of electric energy. In this paper, we present the feasibility of the SUCPT system and examine the transmission properties of SUCPT phenomenon between room temperature and very low temperature at 77 K as long as the receiver is within 1.0 m distance.

  11. Coil concepts for rapid and motion-compensated MR-Imaging of small animals

    International Nuclear Information System (INIS)

    Korn, Matthias

    2009-01-01

    In this work radiofrequency-coils for the imaging of small animals in clinical whole-body MRI-systems were developed. Therefore in a first step single-channel solenoids were designed and characterized. The solenoids had two and three windings respectively, which were implemented as double wires to increase the homogeneity of the receive profile. These coils allow the acquisition of whole-body images of mice with high signal-to-noise ratio and homogeneity over a distance of at least 6.3 cm. Since many imaging experiments require rapid image acquisition, in the next step a novel coil concept was developed, which, due to its geometry, enables parallel imaging in arbitrary directions. A prototype was assembled and tested on phantom and small-animal experiments. With an accelerating factor of R=2, the difference of the SNR in all directions from the theoretical maximum, was less than 1%. In order to compensate physiological motion by the self-gating technique, in this work a coil is presented for the first time, which selectively amplifies the self-gating signal, while - due to a optical detuning technique - preserving the homogeneous illumination of the image. In vivo experiments on a small animal show an amplification of the self-gating signal by at least 40%. (orig.)

  12. Analysis and Optimization of Wireless Power Transfer Efficiency Considering the Tilt Angle of a Coil

    Directory of Open Access Journals (Sweden)

    Wei Huang

    2018-01-01

    Full Text Available Wireless power transfer (WPT based on magnetic resonant coupling is a promising technology in many industrial applications. Efficiency of the WPT system usually depends on the tilt angle of the transmitter or the receiver coil. This work analyzes the effect of the tilt angle on the efficiency of the WPT system with horizontal misalignment. The mutual inductance between two coils located at arbitrary positions with tilt angles is calculated using a numerical analysis based on the Neumann formula. The efficiency of the WPT system with a tilted coil is extracted using an equivalent circuit model with extracted mutual inductance. By analyzing the results, we propose an optimal tilt angle to maximize the efficiency of the WPT system. The best angle to maximize the efficiency depends on the radii of the two coils and their relative position. The calculated efficiencies versus the tilt angle for various WPT cases, which change the radius of RX (r2 = 0.075 m, 0.1 m, 0.15 m and the horizontal distance (y = 0 m, 0.05 m, 0.1 m, are compared with the experimental results. The analytically extracted efficiencies and the extracted optimal tilt angles agree well with those of the experimental results.

  13. Comparison of CT and MRI artefacts from coils and vascular plugs used for portal vein embolization

    Energy Technology Data Exchange (ETDEWEB)

    Geisel, Dominik, E-mail: dominik.geisel@charite.de [Department of Diagnostic and Interventional Radiology, Charité, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin (Germany); Gebauer, Bernhard [Department of Diagnostic and Interventional Radiology, Charité, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin (Germany); Malinowski, Maciej; Stockmann, Martin [Department of General, Visceral and Transplantation Surgery, Charité, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin (Germany); Denecke, Timm [Department of Diagnostic and Interventional Radiology, Charité, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin (Germany)

    2014-04-15

    Purpose: To retrospectively analyze the degree of artefacts in CT and MRI scans caused by coils and vascular plugs used for portal vein embolization (PVE). Materials and methods: All patients who underwent PVE between July 2011 and December 2012 and received either plug or coil embolization additional to particle embolization were retrospectively analyzed. Artefacts causes by embolization materials were measured in CT and MRI scans following PVE. Results: The sum of the artefact diameters caused from coils was significantly higher in CT (188.3 ± 26.1 mm) than in MRI T1 (50.5 ± 6.5 mm) or T2 imaging (39.5 ± 9.7 mm) (P < 0.05). In MRI, the diameter in T1 and T2 sequences did not differ significantly (P = 0.977). The sum of the artefact diameters from vascular plugs in MRI T1 sequences (62.5 ± 8.7 mm) was significantly higher than in CT (46.6 ± 4.8 mm; P < 0.05) and MRI T2 sequences (52.8 ± 3.8 mm; P < 0.05). Conclusion: PVE with particles and vascular plug causes significantly fewer artefacts than PVE with particles and coils on CT scans following embolization, which can be important in the event of vascular complications or in follow-up scans, should the patient become unresectable.

  14. Receiver Test Selection Criteria

    Science.gov (United States)

    2015-03-12

    The DOT requests that GPS manufacturers submit receivers for test in the following TWG categories: - Aviation (non-certified), cellular, general location/navigation, high precision, timing, networks, and space-based receivers - Each receiver should b...

  15. Quench detection system of the EURATOM coil for the Large Coil Task

    International Nuclear Information System (INIS)

    Noether, G.; Gauss, S.; Maurer, W.; Siewerdt, L.; Ulbricht, A.; Wuechner, F.

    1989-01-01

    A special quench detection system has been developed for the EURATOM Large Coil Task (LCT) coil. The system is based on a bridge circuit which uses a special 'two in hand' winding technique for the pancakes of the EURATOM LCT coil. The electronic circuit was designed in a fail safe way to prevent failure of the quench detector due to failure of one of its components. A method for quick balancing of the quench detection system in a large toroidal magnet system was applied. The quench detection system worked very reliably during the experimental phase of the LCT and was within the quench detection level setting of 50 mV, i.e. the system was not sensitive to poloidal field transients at or below this level. Non-electrical methods for quench detection were also investigated. (author)

  16. Design of Electromagnetic Moving-coil type Voice Coil Motor for Scanning mirror of Barcode reader

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Bu Hyun; Lee, Jeong Woo; Shim, Hyun Ho; Park, Sang Goo [Hanbat National Univ., Daejeon (Korea, Republic of); Lee, Seung Yop [Sogang Univ., Seoul (Korea, Republic of)

    2016-01-15

    A voice coil actuator with moving coil type for scanning mirror system of barcode reader has been developed. The actuator has a simple structure including a magnet, a coil and a pin. The performance of the actuator is analyzed by a linearized theoretical model. And the dynamic performance of the proposed actuator is predicted through motor constant and restoring constant obtained by finite element simulations. The theoretical model was verified by the prototype which has 64 Hz resonance frequency and 60 deg reflecting angle. We also discovered that that 3 V input can make the actuator rotate over 61.8 deg reflecting angle at 50 Hz resonance frequency. The proposed actuator can simplify its driving configuration because of its implementation of open-loop control.

  17. ADVANTAGES OF RAPID METHOD FOR DETERMINING SCALE MASS AND DECARBURIZED LAYER OF ROLLED COIL STEEL

    Directory of Open Access Journals (Sweden)

    E. V. Parusov

    2016-08-01

    Full Text Available Purpose. To determine the universal empirical relationships that allow for operational calculation of scale mass and decarbonized layer depth based on the parameters of the technological process for rolled coil steel production. Methodology. The research is carried out on the industrial batches of the rolled steel of SAE 1006 and SAE 1065 grades. Scale removability was determined in accordance with the procedure of «Bekaert» company by the specifi-cations: GA-03-16, GA-03-18, GS-03-02, GS-06-01. The depth of decarbonized layer was identified in accordance with GOST 1763-68 (M method. Findings. Analysis of experimental data allowed us to determine the rational temperature of coil formation of the investigated steel grades, which provide the best possible removal of scale from the metal surface, a minimal amount of scale, as well as compliance of the metal surface color with the require-ments of European consumers. Originality. The work allowed establishing correlation of the basic quality indicators of the rolled coil high carbon steel (scale mass, depth of decarbonized layer and inter-laminar distance in pearlite with one of the main parameters (coil formation temperature of the deformation and heat treatment mode. The re-sulting regression equations, without metallographic analysis, can be used to determine, with a minimum error, the quantitative values of the total scale mass, depth of decarbonized layer and the average inter-lamellar distance in pearlite of the rolled coil high carbon steel. Practical value. Based on the specifications of «Bekaert» company (GA-03-16, GA-03-18, GS-03-02 and GS-06-01 the method of testing descaling by mechanical means from the surface of the rolled coil steel of low- and high-carbon steel grades was developed and approved in the environment of PJSC «ArcelorMittal Kryvyi Rih». The work resulted in development of the rapid method for determination of total and remaining scale mass on the rolled coil steel

  18. Spiral Gradient Coil Design for Use in Cylindrical MRI Systems.

    Science.gov (United States)

    Wang, Yaohui; Xin, Xuegang; Liu, Feng; Crozier, Stuart

    2018-04-01

    In magnetic resonance imaging, the stream function based method is commonly used in the design of gradient coils. However, this method can be prone to errors associated with the discretization of continuous current density and wire connections. In this paper, we propose a novel gradient coil design scheme that works directly in the wire space, avoiding the system errors that may appear in the stream function approaches. Specifically, the gradient coil pattern is described with dedicated spiral functions adjusted to allow the coil to produce the required field gradients in the imaging area, minimal stray field, and other engineering terms. The performance of a designed spiral gradient coil was compared with its stream-function counterpart. The numerical evaluation shows that when compared with the conventional solution, the inductance and resistance was reduced by 20.9 and 10.5%, respectively. The overall coil performance (evaluated by the figure of merit (FoM)) was improved up to 26.5% for the x -gradient coil design; for the z-gradient coil design, the inductance and resistance were reduced by 15.1 and 6.7% respectively, and the FoM was increased by 17.7%. In addition, by directly controlling the wire distributions, the spiral gradient coil design was much sparser than conventional coils.

  19. Retrieval of prolapsed coils during endovascular treatment of cerebral aneurysms

    International Nuclear Information System (INIS)

    Dinc, Hasan; Kuzeyli, Kayhan; Kosucu, Polat; Sari, Ahmet; Cekirge, Saruhan

    2006-01-01

    One of the feared complications during detachable coil embolization of cerebral aneurysms is herniation of a coil loop into the parent artery. Although coil protrusion of one or two loops into the parent vessel may not cause adverse events and in some instances can be ignored, the authors believe that coil retrieval is indicated if a free end is seen pulsating along the blood flow stream to prevent migration of the entire coil mass. In one patient, a microballoon was inflated across the neck of the aneurysm during retrieval of a herniated coil to prevent further coil herniation from the aneurysm sac. We present two cases in which prolapsed coils were successfully retrieved either using a microsnare and balloon combination or a microsnare alone. This report focuses on the efficacy of the Amplatz microsnare for such retrievals and the circumstances in which a herniated coil needs to be retrieved. We report two cases in which embolization coils partially migrated into the parent artery during endovascular treatment of cerebral aneurysm and were retrieved using the Amplatz Nitinol microsnare. (orig.)

  20. Conceptual Design of Alborz Tokamak Poloidal Coils System

    Science.gov (United States)

    Mardani, M.; Amrollahi, R.

    2013-04-01

    The Alborz tokamak is a D-shape cross section tokamak that is under construction in Amirkabir University of Technology. One of the most important parts of tokamak design is the design of the poloidal field system. This part includes the numbers, individual position, currents and number of coil turns of the magnetic field coils. Circular cross section tokamaks have Vertical Field system but since the elongation and triangularity of plasma cross section shaping are important in improving the plasma performance and stability, the poloidal field coils are designed to have a shaped plasma configuration. In this paper the design of vertical field system and the magnetohydrodynamic equilibrium of axisymmetric plasma, as given by the Grad-Shafranov equation will be discussed. The poloidal field coils system consists of 12 circular coils located symmetrically about the equator plane, six inner PF coils and six outer PF coils. Six outer poloidal field coils (PF) are located outside of the toroidal field coils (TF), and six inner poloidal field coils are wound on the inner legs and are located outside of a vacuum vessel.

  1. Transcranial Magnetic Stimulation-coil design with improved focality

    Science.gov (United States)

    Rastogi, P.; Lee, E. G.; Hadimani, R. L.; Jiles, D. C.

    2017-05-01

    Transcranial Magnetic Stimulation (TMS) is a technique for neuromodulation that can be used as a non-invasive therapy for various neurological disorders. In TMS, a time varying magnetic field generated from an electromagnetic coil placed on the scalp is used to induce an electric field inside the brain. TMS coil geometry plays an important role in determining the focality and depth of penetration of the induced electric field responsible for stimulation. Clinicians and basic scientists are interested in stimulating a localized area of the brain, while minimizing the stimulation of surrounding neural networks. In this paper, a novel coil has been proposed, namely Quadruple Butterfly Coil (QBC) with an improved focality over the commercial Figure-8 coil. Finite element simulations were conducted with both the QBC and the conventional Figure-8 coil. The two coil's stimulation profiles were assessed with 50 anatomically realistic MRI derived head models. The coils were positioned on the vertex and the scalp over the dorsolateral prefrontal cortex to stimulate the brain. Computer modeling of the coils has been done to determine the parameters of interest-volume of stimulation, maximum electric field, location of maximum electric field and area of stimulation across all 50 head models for both coils.

  2. Structural analysis of the NET toroidal field coils and conductor

    International Nuclear Information System (INIS)

    Mitchell, N.; Collier, D.; Gori, R.

    1989-01-01

    The NET toroidal field coils will utilise A15-type superconductor at 4.2 K to generate fields up to 11.5 T. The superconductor strands themselves are sensitive to strain, which causes degradation of their current carrying capacity, and thus the detailed behaviour of the coil conductor must be analysied so that the strian can be minimised. This analysis must include the manufacturing processes of the conductor as well as the normal and abnormal loperational loads. The conductor will be insulated and bonded by glass fibre reinforced epoxy resin, with limited bonding shear strength, and the overall support of the complete coil system must be designed to reduce these shear stresses. The coils will be subjected to pulse loads form the poloidal field coils, and analysis of the slip between the various coil components, such as conductors and the coil case, giving rise to frictional heating and possible loss of superconducting properties is another important factor, which has been investigated by a number of stress analyses. The manufacturing, thermal and normal magnetic loads on the coils and the analysis leading to the proposed structural design are described. In addition to the normal operating conditions, there is a range of abnormal load conditions which could result from electrical or mechanical faults on the coils. The effect of these potential faults has been analysed and the coil design modified to prevent catastrophic structural failure. (author). 13 refs.; 8 figs.; 1 tab

  3. Hydrodynamic studies of CNT nanofluids in helical coil heat exchanger

    Science.gov (United States)

    Babita; Sharma, S. K.; Mital Gupta, Shipra; Kumar, Arinjay

    2017-12-01

    Helical coils are extensively used in several industrial processes such as refrigeration systems, chemical reactors, recovery processes etc to accommodate a large heat transfer area within a smaller space. Nanofluids are getting great attention due to their enhanced heat transfer capability. In heat transfer equipments, pressure drop is one of the major factors of consideration for pumping power calculations. So, the present work is aimed to study hydrodynamics of CNT nanofluids in helical coils. In this study, pressure drop characteristics of CNT nanofluid flowing inside horizontal helical coils are investigated experimentally. The helical coil to tube diameter was varied from 11.71 to 27.34 keeping pitch of the helical coil constant. Double distilled water was used as basefluid. SDBS and GA surfactants were added to stablilize CNT nanofluids. The volumetric fraction of CNT nanofluid was varied from 0.003 vol% to 0.051 vol%. From the experimental data, it was analyzed that the friction factor in helical coils is greater than that of straight tubes. Concentration of CNT in nanofluids also has a significant influence on the pressure drop/friction factor of helical coils. At a constant concentration of CNT, decreasing helical coil to tube diameter from 27.24 to 11.71, fanning friction factor of helical coil; f c increases for a constant value of p/d t. This increase in the value of fanning friction factor can be attributed to the secondary flow of CNT nanofluid in helical coils.

  4. Coil optimisation for transcranial magnetic stimulation in realistic head geometry.

    Science.gov (United States)

    Koponen, Lari M; Nieminen, Jaakko O; Mutanen, Tuomas P; Stenroos, Matti; Ilmoniemi, Risto J

    Transcranial magnetic stimulation (TMS) allows focal, non-invasive stimulation of the cortex. A TMS pulse is inherently weakly coupled to the cortex; thus, magnetic stimulation requires both high current and high voltage to reach sufficient intensity. These requirements limit, for example, the maximum repetition rate and the maximum number of consecutive pulses with the same coil due to the rise of its temperature. To develop methods to optimise, design, and manufacture energy-efficient TMS coils in realistic head geometry with an arbitrary overall coil shape. We derive a semi-analytical integration scheme for computing the magnetic field energy of an arbitrary surface current distribution, compute the electric field induced by this distribution with a boundary element method, and optimise a TMS coil for focal stimulation. Additionally, we introduce a method for manufacturing such a coil by using Litz wire and a coil former machined from polyvinyl chloride. We designed, manufactured, and validated an optimised TMS coil and applied it to brain stimulation. Our simulations indicate that this coil requires less than half the power of a commercial figure-of-eight coil, with a 41% reduction due to the optimised winding geometry and a partial contribution due to our thinner coil former and reduced conductor height. With the optimised coil, the resting motor threshold of abductor pollicis brevis was reached with the capacitor voltage below 600 V and peak current below 3000 A. The described method allows designing practical TMS coils that have considerably higher efficiency than conventional figure-of-eight coils. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Polymer therapeutics with a coiled coil motif targeted against murine BCL1 leukemia

    Czech Academy of Sciences Publication Activity Database

    Pola, Robert; Laga, Richard; Ulbrich, Karel; Sieglová, Irena; Král, Vlastimil; Fábry, Milan; Kabešová, Martina; Kovář, Marek; Pechar, Michal

    2013-01-01

    Roč. 14, č. 3 (2013), s. 881-889 ISSN 1525-7797 R&D Projects: GA ČR GAP301/11/0325; GA AV ČR IAAX00500803 Institutional research plan: CEZ:AV0Z50520514 Institutional support: RVO:61389013 ; RVO:61388971 ; RVO:68378050 Keywords : coiled coil * polymer therapeutics * scFv Subject RIV: CD - Macromolecular Chemistry; EC - Immunology (MBU-M); EB - Genetics ; Molecular Biology (UMG-J) Impact factor: 5.788, year: 2013

  6. Polymer cancerostatics with a coiled coil motif targeted against murine leukemia

    Czech Academy of Sciences Publication Activity Database

    Pechar, Michal; Pola, Robert; Janoušková, Olga; Sieglová, Irena; Král, Vlastimil; Fábry, Milan; Tomalová, Barbora; Kovář, Marek

    2017-01-01

    Roč. 6, 4 (Suppl) (2017), s. 36 ISSN 2325-9604. [International Conference and Exhibition on Nanomedicine and Drug Delivery. 29.05.2017-31.05.2017, Osaka] R&D Projects: GA ČR(CZ) GA16-17207S Institutional support: RVO:61389013 ; RVO:68378050 ; RVO:61388971 Keywords : coiled coil * polymer cancerostatics * active targeting Subject RIV: CD - Macromolecular Chemistry; EC - Immunology (MBU-M) https://www.scitechnol.com/conference-abstracts/scientific-tracks-abstracts/nanodelivery-2017-proceedings.html

  7. Coil Migration after Transarterial Coil Embolization of a Splenic Artery Pseudoaneurysm

    Directory of Open Access Journals (Sweden)

    Bezawit D. Tekola

    2013-11-01

    Full Text Available A 48-year-old man with a history of splenic artery pseudoaneurysm requiring transarterial embolization 3 months earlier presented to the emergency department with abdominal pain and fever. Computed tomography showed evidence of embolization coil fragments within the gastrointestinal tract. Upper endoscopy showed a large gastric ulcer with numerous embolization coils extruding into the gastric lumen. The patient underwent partial gastrectomy, distal pancreatectomy and resection of the splenic artery pseudoaneurysm. This case illustrates a rare delayed complication of transarterial embolization of a splenic artery pseudoaneurysm.

  8. Endovascular treatment of posterior cerebral artery aneurysms using detachable coils

    Energy Technology Data Exchange (ETDEWEB)

    Roh, Hong Gee [Kangwon National University Hospital, Department of Radiology, Chuncheon, Kangwon-do (Korea); Konkuk University Hospital, Department of Radiology, Seoul (Korea); Kim, Sam Soo; Han, Heon [Kangwon National University Hospital, Department of Radiology, Chuncheon, Kangwon-do (Korea); Kang, Hyun-Seung [Konkuk University Hospital, Department of Neurosurgery, Seoul (Korea); Moon, Won-Jin [Konkuk University Hospital, Department of Radiology, Seoul (Korea); Byun, Hong Sik [Sungkyunkwan University School of Medicine, Department of Radiology and Center for Imaging Science, Samsung Medical Center, Seoul (Korea)

    2008-03-15

    Aneurysms of the posterior cerebral artery (PCA) are rare, and most of the studies reported in the literature in which the endovascular approach was applied were carried out on a limited number of patients with PCA aneurysms. We retrospectively reviewed our cases of PCA aneurysms - at various locations and of differing shapes - that received endovascular treatment and evaluated the treatment outcome. From January 1996 to December 2006, 13 patients (eight females and five males) with 17 PCA aneurysms (nine fusiform and eight saccular) were treated using the endovascular approach. The age of the patients ranged from 20 to 67 years, with a mean age of 44 years. Of the 13 patients, ten presented with intracranial hemorrhage, and one patient, with a large P2 aneurysm, presented with trigeminal neuralgia; the aneurysms were asymptomatic in the remaining two patients. All 13 patients were successfully treated, with only one procedure-related symptomatic complication. Seven patients were treated by occlusion of the aneurysm and parent artery together; five patients, by selective embolization of the aneurysm; one patient, by partial coiling. Although infarctions were found in two patients treated with selective embolization and in three patients treated with parent artery occlusion, only one patient with a ruptured P2 aneurysm treated with parent artery occlusion developed transient amnesia as an ischemic symptom. Posterior cerebral artery aneurysms can be treated safely with either occlusion of the aneurysm together with the PCA or with a selective coil embolization. Infarctions may occur after endovascular treatment, but they are rarely the cause of a disabling symptom. (orig.)

  9. Dryout occurrence in a helically coiled steam generator for nuclear power application

    Directory of Open Access Journals (Sweden)

    Santini L.

    2014-03-01

    Full Text Available Dryout phenomena have been experimentally investigated in a helically coiled steam generator tube. The experiences carried out in the present work are part of a wide experimental program devoted to the study of a GEN III+ innovative nuclear power plant [1].The experimental facility consists in an electrically heated AISI 316L stainless steel coiled tube. The tube is 32 meters long, 12.53 mm of inner diameter, with a coil diameter of 1m and a pitch of 0.79 m, resulting in a total height of the steam generator of 8 meters. The thermo-hydraulics conditions for dryout investigations covered a spectrum of mass fluxes between 199 and 810 kg/m2s, the pressures ranges from 10.7 to 60.7 bar, heat fluxes between 43.6 to 209.3 kW/m2.Very high first qualities dryout, between 0.72 and 0.92, were found in the range of explored conditions, comparison of our results with literature available correlations shows the difficulty in predicting high qualities dryout in helical coils., immediately following the heading. The text should be set to 1.15 line spacing. The abstract should be centred across the page, indented 15 mm from the left and right page margins and justified. It should not normally exceed 200 words.

  10. The heterotrimeric laminin coiled-coil domain exerts anti-adhesive effects and induces a pro-invasive phenotype.

    Directory of Open Access Journals (Sweden)

    Patricia Santos-Valle

    Full Text Available Laminins are large heterotrimeric cross-shaped extracellular matrix glycoproteins with terminal globular domains and a coiled-coil region through which the three chains are assembled and covalently linked. Laminins are key components of basement membranes, and they serve as attachment sites for cell adhesion, migration and proliferation. In this work, we produced a recombinant fragment comprising the entire laminin coiled-coil of the α1-, β1-, and γ1-chains that assemble into a stable heterotrimeric coiled-coil structure independently of the rest of the molecule. This domain was biologically active and not only failed to serve as a substrate for cell attachment, spreading and focal adhesion formation but also inhibited cell adhesion to laminin when added to cells in a soluble form at the time of seeding. Furthermore, gene array expression profiling in cells cultured in the presence of the laminin coiled-coil domain revealed up-regulation of genes involved in cell motility and invasion. These findings were confirmed by real-time quantitative PCR and zymography assays. In conclusion, this study shows for the first time that the laminin coiled-coil domain displays anti-adhesive functions and has potential implications for cell migration during matrix remodeling.

  11. Fifty years of coiled-coils and alpha-helical bundles: a close relationship between sequence and structure.

    Science.gov (United States)

    Parry, David A D; Fraser, R D Bruce; Squire, John M

    2008-09-01

    alpha-Helical coiled coils are remarkable for the diversity of related conformations that they adopt in both fibrous and globular proteins, and for the range of functions that they exhibit. The coiled coils are based on a heptad (7-residue), hendecad (11-residue) or a related quasi-repeat of apolar residues in the sequences of the alpha-helical regions involved. Most of these, however, display one or more sequence discontinuities known as stutters or stammers. The resulting coiled coils vary in length, in the number of chains participating, in the relative polarity of the contributing alpha-helical regions (parallel or antiparallel), and in the pitch length and handedness of the supercoil (left- or right-handed). Functionally, the concept that a coiled coil can act only as a static rod is no longer valid, and the range of roles that these structures have now been shown to exhibit has expanded rapidly in recent years. An important development has been the recognition that the delightful simplicity that exists between sequence and structure, and between structure and function, allows coiled coils with specialized features to be designed de novo.

  12. Split coil made of (RE)BCO pancake coils for IC(B) anisotropy measurements of superconductors

    International Nuclear Information System (INIS)

    Frolek, L; Pardo, E; Gömöry, F; Šouc, J; Pitel, J

    2014-01-01

    Measurement of the I c (B) anisotropy is standard characterization of superconducting tapes, wires or cables. This contribution presents a split coil consisting on two superconducting pancake coils in order to generate the magnetic field necessary for this kind of measurement. Both coils were made using (RE)BCO – based second generation (2G) coated conductor tape with cross section 0.1 mm × 12 mm. The individual turns of the tape were insulated by a fiberglass tape without impregnation. These coils have identical inner and outer diameter and number of turns. Their inner and outer diameters are 50 mm and 80 mm, respectively, and they have 62 turns. The length of conductor in each coil is approximately 13 m. The distance between both pancake coils is 22 mm. Individual coils and the complete split coil were characterized in liquid nitrogen bath. Their parameters, like the critical currents, E(I) characteristics and magnetic field of complete split coil, were measured and interpreted. The split coil can be used up to magnetic fields of 210 mT. The length between the potential taps on the sample can be up to 20 mm, while the magnetic field decrease is lower than 1% on this length.

  13. Comparison of the association of sac growth and coil compaction with recurrence in coil embolized cerebral aneurysms.

    Directory of Open Access Journals (Sweden)

    Anna L Hoppe

    Full Text Available In recurrent cerebral aneurysms treated by coil embolization, coil compaction is regarded as the presumptive mechanism. We test the hypothesis that aneurysm growth is the primary recurrence mechanism. We also test the hypothesis that the coil mass will translate a measurable extent when recurrence occurs.An objective, quantitative image analysis protocol was developed to determine the volumes of aneurysms and coil masses during initial and follow-up visits from 3D rotational angiograms. The population consisted of 15 recurrence and 12 non-recurrence control aneurysms initially completely coiled at a single center. An investigator sensitivity study was performed to assess the objectivity of the methods. Paired Wilcoxon tests (p<0.05, one-tailed were performed to assess for aneurysm and coil growth. The translation of the coil mass center at follow-up was computed. A Mann Whitney U-Test (p<0.05, one-tailed was used to compare translation of coil mass centers between recurrence and control subjects.Image analysis protocol was found to be insensitive to the investigator. Aneurysm growth was evident in the recurrence cohort (p=0.003 but not the control (p=0.136. There was no evidence of coil compaction in either the recurrence or control cohorts (recurrence: p=0.339; control: p=0.429. The translation of the coil mass centers was found to be significantly larger in the recurrence cohort than the control cohort (p=0.047.Aneurysm sac growth, not coil compaction, was the primary mechanism of recurrence following successful coil embolization. The coil mass likely translates to a measurable extent when recurrence occurs and has the potential to serve as a non-angiographic recurrence marker.

  14. An assessment of heat transfer models of water flow in helically coiled tubes based on selected experimental datasets

    International Nuclear Information System (INIS)

    Gou, Junli; Ma, Haifu; Yang, Zijiang; Shan, Jianqiang

    2017-01-01

    Highlights: •A review of heat transfer characteristics for water flow in helically coiled tubes are conducted. •An assessment of heat transfer models under different heat transfer modes in helically coiled tubes are performed. •This work could provide references for the use of the correlations and for further studies. -- Abstract: This paper presents an assessment of the heat transfer models under different heat transfer modes for water flow in helically coiled tubes based on the compiled datasets from the reviewed literatures. For single phase flow, most of the correlations of the heat transfer coefficient can fit well to the experiments. The correlations of Xin-Ebadian, Dravid and Kalb-Seader for laminar flow and those of Seban-McLaughlim, Mori-Nakayama, Xin-Ebadian, Hardik, Rogers-Mayhew, Mikaila-Poskas and El-Genk-Schriener for turbulent flow are recommended. For flow boiling heat transfer, Steiner-Taborek correlation could be utilized to predict the boiling heat transfer coefficients in helically coiled tubes for a relatively wide range of parameters. For dryout quality, the correlations of Hwang et al. and Santini et al. give relatively better predictions than others. However, more accurate correlations for flow boiling heat transfer coefficient and dryout quality need to be developed based on further investigations with wider parameter ranges in the future. The present work could provide references for the investigators for future uses of those correlations and for performing further investigations on the heat transfer characteristics of water flow in helically coiled tubes.

  15. New method to design stellarator coils without the winding surface

    Science.gov (United States)

    Zhu, Caoxiang; Hudson, Stuart R.; Song, Yuntao; Wan, Yuanxi

    2018-01-01

    Finding an easy-to-build coils set has been a critical issue for stellarator design for decades. Conventional approaches assume a toroidal ‘winding’ surface, but a poorly chosen winding surface can unnecessarily constrain the coil optimization algorithm, This article presents a new method to design coils for stellarators. Each discrete coil is represented as an arbitrary, closed, one-dimensional curve embedded in three-dimensional space. A target function to be minimized that includes both physical requirements and engineering constraints is constructed. The derivatives of the target function with respect to the parameters describing the coil geometries and currents are calculated analytically. A numerical code, named flexible optimized coils using space curves (FOCUS), has been developed. Applications to a simple stellarator configuration, W7-X and LHD vacuum fields are presented.

  16. Electromagnetic results of the Japanese LCT coil's domestic test

    International Nuclear Information System (INIS)

    Nishi, Masataka; Okuno, Kiyoshi; Takahashi, Yoshikazu; Tsuji, Hiroshi; Ando, Toshinari; Shimamoto, Susumu

    1984-01-01

    The domestic test of the Japanese LCT coil was carried out in 1982. During this test, the coil was charged up to the single coil's 100% state (10.22kA, 6.4T, 106MJ) four times and experienced no quenche. at the 100% charging state, coil stability was tested by using heaters installed in the conductor. A half turn length normal zone (about 5 m) generated by heaters was spontenously disappeared in 2 second. This normalized zone included the highest magnetic field position. The transport current which gives the stable limit is extraporated to be about 12.5kA at 8T by this test result. The dump test was carried out also from the 100% charging state. At that time, about 90% of the coil's stored energy was extracted by the dump resistor and the coil was not damaged. (author)

  17. Mechanical behavior of the ATLAS B0 model coil

    CERN Document Server

    Foussat, A; Acerbi, E; Alessandria, F; Berthier, R; Broggi, F; Daël, A; Dudarev, A; Mayri, C; Miele, P; Reytier, M; Rossi, L; Sorbi, M; Sun, Z; ten Kate, H H J; Vanenkov, I; Volpini, G

    2002-01-01

    The ATLAS B0 model coil has been developed and constructed to verify the design parameters and the manufacture techniques of the Barrel Toroid coils (BT) that are under construction for the ATLAS Detector. Essential for successful operation is the mechanical behavior of the superconducting coil and its support structure. In the ATLAS magnet test facility, a magnetic mirror is used to reproduce in the model coil the electromagnetic forces of the BT coils when assembled in the final Barrel Toroid magnet system. The model coil is extensively equipped with mechanical instrumentation to monitor stresses and force levels as well as contraction during a cooling down and excitation up to nominal current. The installed set up of strain gauges, position sensors and capacitive force transducers is presented. Moreover the first mechanical results in terms of expected main stress, strain and deformation values are presented based on detailed mechanical analysis of the design. (7 refs).

  18. Investigation of the mechanical and electrical properties of superconducting coils

    International Nuclear Information System (INIS)

    Saito, T.; Yamagiwa, T.; Hara, K.; Kojima, Y.; Hosoyama, K.; Mori, A.; Nojima, K.; Okamoto, Y.; Takabayashi, S.; Tanaka, T.

    1994-01-01

    Measurement of elastic (Young's) modulus of the superconducting coil and electrical punch-through test have been performed at LBL to understand the mechanical and electrical properties of the superconducting coils. The authors have investigated the elastic modulus of the superconducting coils with six kinds of insulators (made with polyimide-fiberglass-epoxy and all polyimide insulation with epoxy/polyimide adhesive) at room and liquid nitrogen temperatures using samples made of 10 stacks of superconducting cables. The samples are cured under varying compression to investigate the curing pressure dependence of Young's modulus of the coils with six kinds of the insulation system. The electrical punch-through test has also performed under compression at room and liquid nitrogen temperatures to investigate electrical integrity of the insulated coils. The tensile strength test of four kinds of polyimide films has been performed at various temperatures (between cryogenic and coil curing temperatures) to understand the mechanical properties of the films

  19. An automated coil winding machine for the SSC dipole magnets

    International Nuclear Information System (INIS)

    Kamiya, S.; Iwase, T.; Inoue, I.; Fukui, I.; Ishida, K.; Kashiwagi, S.; Sato, Y.; Yoshihara, T.; Yamamoto, S.; Johnson, E.; Gibson, C.

    1990-01-01

    The authors have finished the preliminary design of a fully automated coil winding machine that can be used to manufacture the large number of SSC dipole magnets. The machine aims to perform all coil winding operations including coil parts inserting without human operators at a high productive rate. The machine is composed of five industrial robots. In order to verify the design, they built a small winding machine using an industrial robot and successfully wound a 1 meter long coil using SSC dipole magnet wire. The basic design for the full length coil and the robot winding technique are described in this paper. A fully automated coil winding machine using standard industrial components would be very useful if duplicate production lines are used. 5 figs., 1 tab

  20. Empirical component model to predict the overall performance of heating coils: Calibrations and tests based on manufacturer catalogue data

    International Nuclear Information System (INIS)

    Ruivo, Celestino R.; Angrisani, Giovanni

    2015-01-01

    Highlights: • An empirical model for predicting the performance of heating coils is presented. • Low and high heating capacity cases are used for calibration. • Versions based on several effectiveness correlations are tested. • Catalogue data are considered in approach testing. • The approach is a suitable component model to be used in dynamic simulation tools. - Abstract: A simplified methodology for predicting the overall behaviour of heating coils is presented in this paper. The coil performance is predicted by the ε-NTU method. Usually manufacturers do not provide information about the overall thermal resistance or the geometric details that are required either for the device selection or to apply known empirical correlations for the estimation of the involved thermal resistances. In the present work, heating capacity tables from the manufacturer catalogue are used to calibrate simplified approaches based on the classical theory of heat exchangers, namely the effectiveness method. Only two reference operating cases are required to calibrate each approach. The validity of the simplified approaches is investigated for a relatively high number of operating cases, listed in the technical catalogue of a manufacturer. Four types of coils of three sizes of air handling units are considered. A comparison is conducted between the heating coil capacities provided by the methodology and the values given by the manufacturer catalogue. The results show that several of the proposed approaches are suitable component models to be integrated in dynamic simulation tools of air conditioning systems such as TRNSYS or EnergyPlus

  1. Sound Coiled-Tubing Drilling Practices

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Thomas; Deskins, Greg (Maurer Technology Inc.); Ward, Stephen L. (Advantage Energy Services Ltd); Hightower, Mel

    2001-09-30

    This Coiled-Tubing Drilling (CTD) Sound Practices Manual provides tools needed by CTD engineers and supervisors to plan, design and perform safe, successful CTD operations. As emphasized throughout, both careful planning and attention to detail are mandatory for success. A bibliography of many useful CTD references is presented in Chapter 6. This manual is organized according to three processes: 1) Pre-Job Planning Process, 2) Operations Execution Process, and 3) Post-Job Review Process. Each is discussed in a logical and sequential format.

  2. MRI of the orbit with surface coils

    International Nuclear Information System (INIS)

    Reuther, G.; Requardt, H.; Siemens A.G., Erlangen

    1986-01-01

    MRI of the orbit is strongly improved by the use of surface coils due to a higher signal-to-noise ratio. Oblique views without moving the patient present the optic nerve in full length on one slice. First experience with a small number of cases demonstrates normal anatomy and lesions in detail only at T 1 -weighted pulse sequences. Losses in contrast variation and detail accuracy are caused by movements of the eyeballs. Edge artifacts due to chemical shifting impair the image quality. So far there are no pinters towards tissue-specific signal intensity behaviour. Procedure and most favourable parameters at 1 tesla are given. (orig.) [de

  3. A large stellarator based on modular coils

    International Nuclear Information System (INIS)

    Hamberger, S.M.; Sharp, L.E.; Petersen, L.F.

    1979-06-01

    Although stellarators offer some considerable advantages over tokamaks, difficulties arise in designing large devices due, for instance, to poor plasma access as well as to constructional electromechanical and maintenance problems associated with continous helical windings. This paper describes a design for a fairly large device (major radius 2.1m), based on a set of discrete coil modules arranged in a toroidal configuration to provide the required closed magnetic surfaces, having gaps for unobstructed access to the plasma for diagnostics, etc, and allowing for easy removal for maintenance

  4. Mechanical properties of ISABELLE superconducting coils

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, P.; Bertsche, A.; Fuhrmann, J.; Greene, A.; Grove, E.; Repeta, L.; Short, F.; Tannenbaum, M.; Wanderer, P.

    1981-01-01

    As a part of the manufacturing processes, several mechanical measurements are made on ISABELLE dipoles. These are done both to control the process and to provide information for the evaluation of the behavior of the completed magnets. This paper discusses the Young's Modulus (E = 1-3 x 10/sup 6/ psi), the thermal contraction of the coil assembly (..delta..L/L = 290 +- 17 x 10/sup -5/ at 77/sup 0/K), and the loss of applied prestress with time (approx. 20% for times 20 days).

  5. General Atomic's superconducting toroidal field coil concept

    International Nuclear Information System (INIS)

    Alcorn, J.; Purcell, J.

    1978-01-01

    General Atomic's concept for a superconducting toroidal field coil is presented. The concept is generic for large tokamak devices, while a specific design is indicated for a 3.8 meter (major radius) ignition/burn machine. The concept utilizes bath cooled NbTi conductor to generate a peak field of 10 tesla at 4.2 K. The design is simple and straightforward, requires a minimum of developmental effort, and draws extensively upon the perspective of past experience in the design and construction of large superconducting magnets for high energy physics. Thus, the primary emphasis is upon economy, reliability, and expeditious construction scheduling. (author)

  6. New superconducting coil configuration for energy storage

    International Nuclear Information System (INIS)

    Tokorabet, M.; Mailfert, A.; Colteu, A.

    1998-01-01

    Energy storage using superconducting coils involves the problem of electromagnetic field pollution outside the considered system. Different configurations are widely studied: the torus, the alone solenoid and multiple parallel solenoids enclosed in one container. A new configuration which minimizes the external pollution is studied in this paper. The theoretical system is composed of two spherical distributions of the current which are concentric. The analytical study uses solution of Laplace equations. Parametric study covers energy, flux density and geometrical data. The second study concerns the numerical approach of this design using coaxial solenoids. A comparison between this new system and the known systems is presented as a conclusion. (orig.)

  7. Analytical solutions to SSC coil end design

    International Nuclear Information System (INIS)

    Bossert, R.C.; Brandt, J.S.; Carson, J.A.; Fulton, H.J.; Lee, G.C.; Cook, J.M.

    1989-03-01

    As part of the SCC magnet effort, Fermilab will build and test a series of one meter model SSC magnets. The coils in these magnets will be constructed with several different end configurations. These end designs must satisfy both mechanical and magnetic criteria. Only the mechanical problem will be addressed. Solutions will attempt to minimize stresses and provide internal support for the cable. Different end designs will be compared in an attempt to determine which is most appropriate for the SSC dipole. The mathematics required to create each end configuration will be described. The computer aided design, programming and machine technology needed to make the parts will be reviewed. 2 refs., 10 figs

  8. MRI surface-coil pair with strong inductive coupling.

    Science.gov (United States)

    Mett, Richard R; Sidabras, Jason W; Hyde, James S

    2016-12-01

    A novel inductively coupled coil pair was used to obtain magnetic resonance phantom images. Rationale for using such a structure is described in R. R. Mett et al. [Rev. Sci. Instrum. 87, 084703 (2016)]. The original rationale was to increase the Q-value of a small diameter surface coil in order to achieve dominant loading by the sample. A significant improvement in the vector reception field (VRF) is also seen. The coil assembly consists of a 3-turn 10 mm tall meta-metallic self-resonant spiral (SRS) of inner diameter 10.4 mm and outer diameter 15.1 mm and a single-loop equalization coil of 25 mm diameter and 2 mm tall. The low-frequency parallel mode was used in which the rf currents on each coil produce magnetic fields that add constructively. The SRS coil assembly was fabricated and data were collected using a tissue-equivalent 30% polyacrylamide phantom. The large inductive coupling of the coils produces phase-coherency of the rf currents and magnetic fields. Finite-element simulations indicate that the VRF of the coil pair is about 4.4 times larger than for a single-loop coil of 15 mm diameter. The mutual coupling between coils influences the current ratio between the coils, which in turn influences the VRF and the signal-to-noise ratio (SNR). Data on a tissue-equivalent phantom at 9.4 T show a total SNR increase of 8.8 over the 15 mm loop averaged over a 25 mm depth and diameter. The experimental results are shown to be consistent with the magnetic resonance theory of the emf induced by spins in a coil, the theory of inductively coupled resonant circuits, and the superposition principle. The methods are general for magnetic resonance and other types of signal detection and can be used over a wide range of operating frequencies.

  9. Magnet coils made from high-temperature superconductor

    International Nuclear Information System (INIS)

    Jenkins, R.G.; Yang, M.; Grovenor, C.R.M.; Goringe, M.J.

    1996-01-01

    We review the progress we have made in constructing HTS coils and report our latest results. Also we describe the cryogen-free operation of one of our HTS coils cooled to 55 K using a Stirling cycle cryocooler. Lastly, we describe how 4 Oxford coils are being used in a project to investigate the controllability of HTS magnets in applications such as ''maglev'' suspension systems. We briefly report the initial findings of this work and describe developments in progress. (orig.)

  10. Focused surface coil for MR imaging of the pituitary

    International Nuclear Information System (INIS)

    Harms, S.E.; Sherry, C.S.; Youshimura, L.; Lokken, R.; Hyde, J.S.

    1987-01-01

    A specially designed surface coil for pituitary MR imaging results in improved image quality over that achieved with conventional pituitary Mr imaging. The coil consists of connected planar pair coils with a variable intercoil distance to accommodate differences in head size. The sensitive field is focused deep to the surface between the two planar pairs. This arrangement optimizes the signal-to-noise ratio and allows better gradient magnification of the pituitary region. Fifteen subjects with a variety of pituitary disorders were imaged

  11. Invited review the coiled coil silk of bees, ants, and hornets.

    Science.gov (United States)

    Sutherland, Tara D; Weisman, Sarah; Walker, Andrew A; Mudie, Stephen T

    2012-06-01

    In this article, we review current knowledge about the silk produced by the larvae of bees, ants, and hornets [Apoidea and Vespoidea: Hymenoptera]. Different species use the silk either alone or in composites for a variety of purposes including mechanical reinforcement, thermal regulation, or humidification. The characteristic molecular structure of this silk is α-helical proteins assembled into tetrameric coiled coils. Gene sequences from seven species are available, and each species possesses a copy of each of four related silk genes that encode proteins predicted to form coiled coils. The proteins are ordered at multiple length scales within the labial gland of the final larval instar before spinning. The insects control the morphology of the silk during spinning to produce either fibers or sheets. The silk proteins are small and non repetitive and have been produced artificially at high levels by fermentation in E. coli. The artificial silk proteins can be fabricated into materials with structural and mechanical properties similar to those of native silks. Copyright © 2011 Wiley Periodicals, Inc.

  12. d-Cysteine Ligands Control Metal Geometries within De Novo Designed Three-Stranded Coiled Coils

    DEFF Research Database (Denmark)

    Ruckthong, Leela; Peacock, Anna F.A.; Pascoe, Cherilyn E.

    2017-01-01

    Although metal ion binding to naturally occurring l-amino acid proteins is well documented, understanding the impact of the opposite chirality (d-)amino acids on the structure and stereochemistry of metals is in its infancy. We examine the effect of a d-configuration cysteine within a designed l......-amino acid three-stranded coiled coil in order to enforce a precise coordination number on a metal center. The d chirality does not alter the native fold, but the side-chain re-orientation modifies the sterics of the metal binding pocket. l-Cys side chains within the coiled-coil structure have previously...... by comparison of the structure of ZnIICl(CSL16DC)3 2- to the published structure of ZnII(H2O)(GRAND-CSL12AL16LC)3 -. Moreover, spectroscopic analysis indicates that the CdII geometry observed by using l-Cys ligands (a mixture of three- and four-coordinate CdII) is altered to a single four-coordinate species...

  13. Structure and Misfolding of the Flexible Tripartite Coiled-Coil Domain of Glaucoma-Associated Myocilin

    Energy Technology Data Exchange (ETDEWEB)

    Hill, Shannon E.; Nguyen, Elaine; Donegan, Rebecca K.; Patterson-Orazem, Athéna C.; Hazel, Anthony; Gumbart, James C.; Lieberman, Raquel L.

    2017-11-01

    Glaucoma-associated myocilin is a member of the olfactomedins, a protein family involved in neuronal development and human diseases. Molecular studies of the myocilin N-terminal coiled coil demonstrate a unique tripartite architecture: a Y-shaped parallel dimer-of-dimers with distinct tetramer and dimer regions. The structure of the dimeric C-terminal 7-heptad repeats elucidates an unexpected repeat pattern involving inter-strand stabilization by oppositely charged residues. Molecular dynamics simulations reveal an alternate accessible conformation in which the terminal inter-strand disulfide limits the extent of unfolding and results in a kinked configuration. By inference, full-length myocilin is also branched, with two pairs of C-terminal olfactomedin domains. Selected variants within the N-terminal region alter the apparent quaternary structure of myocilin but do so without compromising stability or causing aggregation. In addition to increasing our structural knowledge of naturally occurring extracellular coiled coils and biomedically important olfactomedins, this work broadens the scope of protein misfolding in the pathogenesis of myocilin-associated glaucoma.

  14. Structure and Misfolding of the Flexible Tripartite Coiled-Coil Domain of Glaucoma-Associated Myocilin.

    Science.gov (United States)

    Hill, Shannon E; Nguyen, Elaine; Donegan, Rebecca K; Patterson-Orazem, Athéna C; Hazel, Anthony; Gumbart, James C; Lieberman, Raquel L

    2017-11-07

    Glaucoma-associated myocilin is a member of the olfactomedins, a protein family involved in neuronal development and human diseases. Molecular studies of the myocilin N-terminal coiled coil demonstrate a unique tripartite architecture: a Y-shaped parallel dimer-of-dimers with distinct tetramer and dimer regions. The structure of the dimeric C-terminal 7-heptad repeats elucidates an unexpected repeat pattern involving inter-strand stabilization by oppositely charged residues. Molecular dynamics simulations reveal an alternate accessible conformation in which the terminal inter-strand disulfide limits the extent of unfolding and results in a kinked configuration. By inference, full-length myocilin is also branched, with two pairs of C-terminal olfactomedin domains. Selected variants within the N-terminal region alter the apparent quaternary structure of myocilin but do so without compromising stability or causing aggregation. In addition to increasing our structural knowledge of naturally occurring extracellular coiled coils and biomedically important olfactomedins, this work broadens the scope of protein misfolding in the pathogenesis of myocilin-associated glaucoma. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Structure of a designed, right-handed coiled-coil tetramer containing all biological amino acids.

    Science.gov (United States)

    Sales, Mark; Plecs, Joseph J; Holton, James M; Alber, Tom

    2007-10-01

    The previous design of an unprecedented family of two-, three-, and four-helical, right-handed coiled coils utilized nonbiological amino acids to efficiently pack spaces in the oligomer cores. Here we show that a stable, right-handed parallel tetrameric coiled coil, called RH4B, can be designed entirely using biological amino acids. The X-ray crystal structure of RH4B was determined to 1.1 Angstrom resolution using a designed metal binding site to coordinate a single Yb(2+) ion per 33-amino acid polypeptide chain. The resulting experimental phases were particularly accurate, and the experimental electron density map provided an especially clear, unbiased view of the molecule. The RH4B structure closely matched the design, with equivalent core rotamers and an overall root-mean-square deviation for the N-terminal repeat of the tetramer of 0.24 Angstrom. The clarity and resolution of the electron density map, however, revealed alternate rotamers and structural differences between the three sequence repeats in the molecule. These results suggest that the RH4B structure populates an unanticipated variety of structures.

  16. Coil extensions improve line shapes by removing field distortions

    Science.gov (United States)

    Conradi, Mark S.; Altobelli, Stephen A.; McDowell, Andrew F.

    2018-06-01

    The static magnetic susceptibility of the rf coil can substantially distort the field B0 and be a dominant source of line broadening. A scaling argument shows that this may be a particular problem in microcoil NMR. We propose coil extensions to reduce the distortion. The actual rf coil is extended to a much longer overall length by abutted coil segments that do not carry rf current. The result is a long and nearly uniform sheath of copper wire, in terms of the static susceptibility. The line shape improvement is demonstrated at 43.9 MHz and in simulation calculations.

  17. Performance verification tests of JT-60SA CS model coil

    Energy Technology Data Exchange (ETDEWEB)

    Obana, Tetsuhiro, E-mail: obana.tetsuhiro@LHD.nifs.ac.jp [National Institute for Fusion Science, 322-6 Oroshi, Toki, Gifu 509-5292 (Japan); Murakami, Haruyuki [Japan Atomic Energy Agency, 801-1 Mukoyama, Naka, Ibaraki 311-0193 (Japan); Takahata, Kazuya; Hamaguchi, Shinji; Chikaraishi, Hirotaka; Mito, Toshiyuki; Imagawa, Shinsaku [National Institute for Fusion Science, 322-6 Oroshi, Toki, Gifu 509-5292 (Japan); Kizu, Kaname; Natsume, Kyohei; Yoshida, Kiyoshi [Japan Atomic Energy Agency, 801-1 Mukoyama, Naka, Ibaraki 311-0193 (Japan)

    2015-11-15

    Highlights: • The performance of the JT-60SA CS model coil was verified. • The CS model coil comprised a quad-pancake wound with a Nb{sub 3}Sn CIC conductor. • The CS model coil met the design requirements. - Abstract: As a final check of the coil manufacturing method of the JT-60 Super Advanced (JT-60SA) central solenoid (CS), we verified the performance of a CS model coil. The model coil comprised a quad-pancake wound with a Nb{sub 3}Sn cable-in-conduit conductor. Measurements of the critical current, joint resistance, pressure drop, and magnetic field were conducted in the verification tests. In the critical-current measurement, the critical current of the model coil coincided with the estimation derived from a strain of −0.62% for the Nb{sub 3}Sn strands. As a result, critical-current degradation caused by the coil manufacturing process was not observed. The results of the performance verification tests indicate that the model coil met the design requirements. Consequently, the manufacturing process of the JT-60SA CS was established.

  18. Reactivation of Open Coil Springs: A Novel Procedure

    Directory of Open Access Journals (Sweden)

    Sanjeeb Kumar Sahu

    2012-01-01

    Full Text Available Open coil springs are commonly used in orthodontic practice to create space for a palatally or lingually blocked out tooth. However, very often the clinician encounters a situation where the inter-bracket span is very less and the open coil spring is not long enough to open the required space needed for alignment. In such situations, the clinician needs to remove the arch wire and reinserts a longer coil spring. A new simple and cost-effective technique describes an intraoral reactivation of an open coil spring without the need for removal of the base archwire with the additional benefit of preventing unwanted forces to the adjacent teeth.

  19. Switching transients in the MFTF yin-yang coils

    International Nuclear Information System (INIS)

    Owen, E.W.; Shimer, D.W.

    1982-01-01

    This report is a study of the transients caused by the fast dump of large superconducting coils. Theoretical analysis, computer simulation, and actual measurements are used. Theoretical analysis can only be applied to the simplest of models. In the computer simulations two models are used, one in which the coil is divided into ten segments and another in which a single coil is employed. The circuit breaker that interrupts the current to the power supply, causing a fast dump, is represented by a time and current dependent conductance. Actual measurements are limited to measurements made incidental to the coils' performance tests

  20. Coil Array Design Inspired on the Kepler's Lenten Pretzel

    International Nuclear Information System (INIS)

    Vazquez, F.; Solis, S. E.; Rodriguez, A. O.

    2008-01-01

    The RF coil arrays are an important part in Magnetic Resonance Imaging, since they are the main device for transmission and reception of the magnetic resonance signal. An RF coil array with a new configuration based on the Kepler's Lenten pretzel for the geocentric path of Mars is proposed in this work. The evenly distributed trajectories may serve as the basic configuration to form a coil array to adequately cover a region of interest for magnetic resonance experiments. The main goal is to investigate the electromagnetic properties of this coil array geometry to obtain an optimal design for its further construction. Hence, the electromagnetic properties of the coil array were numerical simulated using the finite element method and the quasi-static approach. Resulting simulations showed that there is an important concentration of magnetic field lines at the centre of the coil array. This is an advantage over other coil arrays where the magnetic field usually decreased at their geometrical centre. Both the electric and magnetic fields had also a very good uniformity. These characteristics made this coil design a good candidate for applications where the use of multi-coil technology is mandatory

  1. Protection of large-stored-energy superconducting coils

    International Nuclear Information System (INIS)

    Kircher, F.

    1975-11-01

    When the stored energy of superconducting magnets increases, the problem of the protection of the coil when a quench occurs becomes more and more important, especially if the structure of the coil is such that the energy can be dissipated only in a small part of the coil. The aim of this paper is first to describe a program which enables to predict the increase of temperature inside the coil for several kinds of protection and to give results for KEK pulsed dipoles (under construction and planned for TRISTAN). (auth.)

  2. Magnetic field, inductance of circular coil and solenoids

    International Nuclear Information System (INIS)

    Ramirez Hoyos, P.; Barbero Garcia, A.J.; Mafe Matoses, S.

    1995-01-01

    The self-inductance of a current-carrying circular coil and the mutual inductances of the Helmholtz coils and coil-sole-noid systems have been measured and calculated theoretically. The experiments and the required equipment are suited to an undergraduate laboratory. The theoretical calculation involve the use of simple numerical integration methods for evaluating the magnetic field of the circular coil and the inductances. The calculated values agree with the measurements within the experimental error. The material presented can be proposed to the students as a laboratory project. (Author) 7 refs

  3. Stability analysis of high temperature superconducting coil in liquid hydrogen

    International Nuclear Information System (INIS)

    Nakayama, T.; Yagai, T.; Tsuda, M.; Hamajima, T.

    2007-01-01

    Recently, it is expected that hydrogen plays an important role in energy source including electric power in near future. Liquid hydrogen has high potential for cooling down superconducting coil wound with high temperature superconductors (HTS), such as BSCCO, YBCO. In this paper, we study stabilities of the coils wound with BSCCO tapes, which are immersed in the liquid hydrogen, and compare stability results with those cooled by liquid helium. We treat a minimum propagation zone (MPZ) theory to evaluate the coil stability considering boiling heat flux of the liquid hydrogen, and specific heat, heat conduction and resistivity of HTS materials as a function of temperature. It is found that the coil cooled by the liquid hydrogen has higher stability margin than that cooled by the liquid helium. We compare the stability margins of both coils wound with Bi-2223/Ag tape and Bi-2212/Ag tape in liquid hydrogen. As a result, it is found that the stability of Bi-2212 coil is equivalent to that of Bi-2223 coil in low and high magnetic field, while the maximum current of Bi-2212 coil exceeds a little bit that of Bi-2223 coil in both magnetic fields

  4. Finite element modeling of TFTR poloidal field coils

    International Nuclear Information System (INIS)

    Baumgartner, J.A.; O'Toole, J.A.

    1986-01-01

    The Tokamak Fusion Test Reactor (TFTR) Poloidal Field (PF) coils were originally analyzed to TFTR design conditions. The coils have been reanalyzed by PPPL and Grumman to determine operating limits under as-built conditions. Critical stress levels, based upon data obtained from the reanalysis of each PF coil, are needed for input to the TFTR simulation code algorithms. The primary objective regarding structural integrity has been to ascertain the magnitude and location of critical internal stresses in each PF coil due to various combinations of electromagnetic and thermally induced loads. For each PF coil, a global finite element model (FEM) of a coil sector is being analyzed to obtain the basic coil internal loads and displacements. Subsequent fine mesh local models of the coil lead stem and lead spur regions produce the magnitudes and locations of peak stresses. Each copper turn and its surrounding insulation are modeled using solid finite elements. The corresponding electromagnetic and thermal analyses are similarly modeled. A series of test beams were developed to determine the best combination of MSC/NASTRAN-type finite elements for use in PF coil analysis. The results of this analysis compare favorably with those obtained by the earlier analysis which was limited in scope

  5. Characteristics of parallel reverse coil inductors with different current ratio in coils used for melting in a suspension state

    International Nuclear Information System (INIS)

    Fogel', A.A.; Sidorova, T.A.; Smirnov, V.V.; Mezdrogina, M.M.

    1975-01-01

    The paper studies the effect of the ratio of the currents in the coils of an inductor with a parallel-switched ''reverse coil'', where the ratio of the current in the upper coil to that in the lower coil is 0.72. A region of stable dependence of liquid niobium characterized by upper and lower limits has been found. The maximum permissible volume of liquid niobium increases as the ratio of current in the upper coil to current in the lower coil decreases. The temperature dependences of niobium on the voltage in the inductor have been derived. Experiments have shown that the greater the capillary constant of niobium, the larger the region of stable dependence of liquid niobium, the larger the range of possible temperature regulation and the larger the maximum permissible volume. (N.K.)

  6. Poynting vector analysis for wireless power transfer between magnetically coupled coils with different loads.

    Science.gov (United States)

    Guo, Yunsheng; Li, Jiansheng; Hou, Xiaojuan; Lv, Xiaolong; Liang, Hao; Zhou, Ji; Wu, Hongya

    2017-04-07

    Wireless power transfer is a nonradiative type of transmission that is performed in the near-field region. In this region, the electromagnetic fields that are produced by both the transmitting and receiving coils are evanescent fields, which should not transmit energy. This then raises the question of how the energy can be transferred. Here we describe a theoretical study of the two evanescent field distributions at different terminal loads. It is shown that the essential principle of wireless energy transfer is the superposition of the two evanescent fields, and the resulting superimposed field is mediated through the terminal load. If the terminal load is either capacitive or inductive, then the superimposed field cannot transfer the energy because its Poynting vector is zero; in contrast, if the load is resistive, energy can then be conveyed from the transmitting coil to the receiving coil. The simulation results for the magnetic field distributions and the time-domain current waveforms agree very well with the results of the theoretical analysis. This work thus provides a comprehensive understanding of the energy transfer mechanism involved in the magnetic resonant coupling system.

  7. Performance of external and internal coil configurations for prostate investigations at 7 Tesla

    Science.gov (United States)

    Metzger, Gregory J.; van de Moortele, Pierre-Francois; Akgun, Can; Snyder, Carl J.; Moeller, Steen; Strupp, John; Andersen, Peter; Shrivastava, Devashish; Vaughan, Tommy; Ugurbil, Kamil; Adriany, Gregor

    2010-01-01

    Three different coil configurations were evaluated through simulation and experimentally to determine safe operating limits and evaluate subject size dependent performance for prostate imaging at 7 Tesla. The coils included a transceiver endorectal coil (trERC), a 16 channel transceiver external surface array (trESA) and a trESA combined with a receive-only ERC (trESA+roERC). While the transmit B1 (B1+) homogeneity was far superior for the trESA, the maximum achievable B1+ is subject size dependent and limited by transmit chain losses and amplifier performance. For the trERC, limitations in transmit homogeneity greatly compromised image quality and limited coverage of the prostate. Despite these challenges, the high peak B1+ close to the trERC and subject size independent performance provides potential advantages especially for spectroscopic localization where high bandwidth RF pulses are required. On the receive side, the combined trESA+roERC provided the highest SNR and improved homogeneity over the trERC resulting in better visualization of the prostate and surrounding anatomy. In addition, the parallel imaging performance of the trESA+roERC holds strong promise for diffusion weighted imaging and dynamic contrast enhanced MRI. PMID:20740657

  8. A novel method for coiled tubing installation

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, Peter J. [2H Offshore, Houston, TX (United States); Tibbetts, David [Aquactic Engineering and Construction Ltd., Aberdeen (United Kingdom)

    2009-12-19

    Installation of flexible pipe for offshore developments is costly due to the physical cost of the flexible pipe, expensive day rates and the availability of suitable installation vessels. Considering the scarcity of flexible pipe in today's increasingly demanding and busy market, operators are seeking a cost effective solution for installing piping in a range of water depths using vessels which are readily on hand. This paper describes a novel approach to installing reeled coiled tubing, from 1 inch to 5 inch diameter, from the back of a small vessel in water depths from 40 m up to around 1000 m. The uniqueness of the system is the fact that the equipment design is modular and compact. This means that when disassembled, it fits into standard 40 ft shipping containers, and the size allows it to be installed on even relatively small vessels of opportunity, such as anchor handling or installation vessels, from smaller, and cheaper quay side locations. Such an approach is the ideal solution to the problem faced by operators, in that it allows the installation of cheaper, readily available coiled tubing, from cost-effective vessels, which do not need to transit to a pick up the system. (author)

  9. Effect of Inductive Coil Shape on Sensing Performance of Linear Displacement Sensor Using Thin Inductive Coil and Pattern Guide

    Directory of Open Access Journals (Sweden)

    Hiroyuki Wakiwaka

    2011-11-01

    Full Text Available This paper discusses the effect of inductive coil shape on the sensing performance of a linear displacement sensor. The linear displacement sensor consists of a thin type inductive coil with a thin pattern guide, thus being suitable for tiny space applications. The position can be detected by measuring the inductance of the inductive coil. At each position due to the change in inductive coil area facing the pattern guide the value of inductance is different. Therefore, the objective of this research is to study various inductive coil pattern shapes and to propose the pattern that can achieve good sensing performance. Various shapes of meander, triangular type meander, square and circle shape with different turn number of inductive coils are examined in this study. The inductance is measured with the sensor sensitivity and linearity as a performance evaluation parameter of the sensor. In conclusion, each inductive coil shape has its own advantages and disadvantages. For instance, the circle shape inductive coil produces high sensitivity with a low linearity response. Meanwhile, the square shape inductive coil has a medium sensitivity with higher linearity.

  10. Quench detector for large pulsed coils and quench analysis for the LASL/Westinghouse 20 MJ coil

    International Nuclear Information System (INIS)

    Hennessy, M.J.; Heintz, A.W.; Eckels, P.W.

    1981-01-01

    A detection scheme has been devised for use in the test of the 20 Mj Induction Heating Coil. This scheme allows the sensing of plus or minus voltages less than 320 mv resistive in magnitude in coils which will have inductive voltage components as high as /plus or minus/2.5 kv. The network which achieves this sensitivity is stable to less than 12.8 ppm. This method adopted involves the bucking out of the inductive voltage with two secondary co-wound flux sensing coils tapped at locations adjacent to voltage taps in the main superconducting coil. The detection scheme is recommended if large ripple or control voltages exist subsequent to the coil pulse. The most severe event which might quench the coil and/or damage the winding is exposure of the coil to gaseous cooling through lack of proper liquid level control. The detection scheme will protect the coil against this and other abnormal conditions that could damage the coil

  11. Structure of bacteriophage T4 fibritin: a segmented coiled coil and the role of the C-terminal domain.

    Science.gov (United States)

    Tao, Y; Strelkov, S V; Mesyanzhinov, V V; Rossmann, M G

    1997-06-15

    Oligomeric coiled-coil motifs are found in numerous protein structures; among them is fibritin, a structural protein of bacteriophage T4, which belongs to a class of chaperones that catalyze a specific phage-assembly process. Fibritin promotes the assembly of the long tail fibers and their subsequent attachment to the tail baseplate; it is also a sensing device that controls the retraction of the long tail fibers in adverse environments and, thus, prevents infection. The structure of fibritin had been predicted from sequence and biochemical analyses to be mainly a triple-helical coiled coil. The determination of its structure at atomic resolution was expected to give insights into the assembly process and biological function of fibritin, and the properties of modified coiled-coil structures in general. The three-dimensional structure of fibritin E, a deletion mutant of wild-type fibritin, was determined to 2.2 A resolution by X-ray crystallography. Three identical subunits of 119 amino acid residues form a trimeric parallel coiled-coil domain and a small globular C-terminal domain about a crystallographic threefold axis. The coiled-coil domain is divided into three segments that are separated by insertion loops. The C-terminal domain, which consists of 30 residues from each subunit, contains a beta-propeller-like structure with a hydrophobic interior. The residues within the C-terminal domain make extensive hydrophobic and some polar intersubunit interactions. This is consistent with the C-terminal domain being important for the correct assembly of fibritin, as shown earlier by mutational studies. Tight interactions between the C-terminal residues of adjacent subunits counteract the latent instability that is suggested by the structural properties of the coiled-coil segments. Trimerization is likely to begin with the formation of the C-terminal domain which subsequently initiates the assembly of the coiled coil. The interplay between the stabilizing effect of the C

  12. Solutions for Safe Hot Coil Evacuation and Coil Handling in Case of Thick and High Strength Steel

    Directory of Open Access Journals (Sweden)

    Sieberer Stefan

    2016-01-01

    Full Text Available Currently hot rolling plants are entering the market segment for thick gauges and high strength steel grades where the elastic bending property of the strip leads to internal forces in the coil during coiling operation. The strip tends to open. Primetals is investigating several possibilities to facilitate safe coil evacuation and coil handling under spring-back conditions. The contribution includes finite element models of such mechanical solutions. Results of parameter variation and stability limits of case studies are presented in the paper.

  13. Development of Ground Coils with Low Eddy Current Loss by Applying the Compression Molding Method after the Coil Winding

    Science.gov (United States)

    Suzuki, Masao; Aiba, Masayuki; Takahashi, Noriyuki; Ota, Satoru; Okada, Shigenori

    In a magnetically levitated transportation (MAGLEV) system, a huge number of ground coils will be required because they must be laid for the whole line. Therefore, stable performance and reduced cost are essential requirements for the ground coil development. On the other hand, because the magnetic field changes when the superconducting magnet passes by, an eddy current will be generated in the conductor of the ground coil and will result in energy loss. The loss not only increases the magnetic resistance for the train running but also brings an increase in the ground coil temperature. Therefore, the reduction of the eddy current loss is extremely important. This study examined ground coils in which both the eddy current loss and temperature increase were small. Furthermore, quantitative comparison for the eddy current loss of various magnet wire samples was performed by bench test. On the basis of the comparison, a round twisted wire having low eddy current loss was selected as an effective ground coil material. In addition, the ground coils were manufactured on trial. A favorable outlook to improve the size accuracy of the winding coil and uneven thickness of molded resin was obtained without reducing the insulation strength between the coil layers by applying a compression molding after winding.

  14. Magnetic resonance imaging for radiotherapy planning of brain cancer patients using immobilization and surface coils

    Science.gov (United States)

    Hanvey, S.; Glegg, M.; Foster, J.

    2009-09-01

    This study investigated the compatibility of a head and neck immobilization device with magnetic resonance imaging (MRI). The immobilization device is used to position a patient in the same way as when receiving a computed tomography (CT) scan for radiotherapy planning and radiation treatment. The advantage of using immobilization in MR is improved accuracy in CT/MR image registration enabling greater confidence in the delineation of structures. The main practical difficulty in using an immobilization device in MRI is that physical constraints make their use incompatible with head imaging coils. Within this paper we describe a method for MR imaging of the brain which allows the use of head and neck immobilization devices. By a series of image quality tests we obtained the same or better image quality as a multi-channel head coil.

  15. Poster - Thur Eve - 13: Quantifying specific absorption rate of shielded RF coils through electromagnetic simulations for 7-T MRI.

    Science.gov (United States)

    Belliveau, J-G; Gilbert, K M; Abou-Khousa, M; Menon, R S

    2012-07-01

    Ultra-high field MRI has many advantages such as increasing spatial resolution and exploiting contrast never before seen in-vivo. This contrast has been shown to be beneficial for many applications such as monitoring early and late effect to radiation therapy and transient changes during disease to name a few. However, at higher field strengths the RF wave, needed to for transmitting and receiving signal, approaches that of the head. This leads to constructive and deconstructive interference and a non -uniform flip angle over the volume being imaged. A transmit or transceive RF surface coil arrays is currently a method of choice to overcome this problem; however, mutual inductance between elements poses a significant challenge for the designer. A method to decouple elements in such an array is by using circumferential shielding; however, the potential benefits and/or disadvantages have not been investigated. This abstract primarily focuses on understanding power deposition - measured through Specific Absorption Rate - in the sample using circumferentially shielded RF coils. Various geometries of circumferentially shielded coils are explored to determine the behaviour of shield width and its effect on required transmit power and power deposition to the sample. Our results indicate that there is an optimization on shield width depending on the imaging depth. Additionally, the circumferential shield focuses the field more than unshielded coils, meaning that slight SAR may even be lower for circumferential shielded RF coils in array. © 2012 American Association of Physicists in Medicine.

  16. Fault diagnosis and comparing risk for the steel coil manufacturing process using statistical models for binary data

    International Nuclear Information System (INIS)

    Debón, A.; Carlos Garcia-Díaz, J.

    2012-01-01

    Advanced statistical models can help industry to design more economical and rational investment plans. Fault detection and diagnosis is an important problem in continuous hot dip galvanizing. Increasingly stringent quality requirements in the automotive industry also require ongoing efforts in process control to make processes more robust. Robust methods for estimating the quality of galvanized steel coils are an important tool for the comprehensive monitoring of the performance of the manufacturing process. This study applies different statistical regression models: generalized linear models, generalized additive models and classification trees to estimate the quality of galvanized steel coils on the basis of short time histories. The data, consisting of 48 galvanized steel coils, was divided into sets of conforming and nonconforming coils. Five variables were selected for monitoring the process: steel strip velocity and four bath temperatures. The present paper reports a comparative evaluation of statistical models for binary data using Receiver Operating Characteristic (ROC) curves. A ROC curve is a graph or a technique for visualizing, organizing and selecting classifiers based on their performance. The purpose of this paper is to examine their use in research to obtain the best model to predict defective steel coil probability. In relation to the work of other authors who only propose goodness of fit statistics, we should highlight one distinctive feature of the methodology presented here, which is the possibility of comparing the different models with ROC graphs which are based on model classification performance. Finally, the results are validated by bootstrap procedures.

  17. Research of the heat exchanging processes running in the heating and hot water supply loops of the coil heat exchangers

    Directory of Open Access Journals (Sweden)

    Ірина Геннадіївна Шитікова

    2016-11-01

    Full Text Available The fuel-energy complex research has made it possible to disclose a huge power-saving potential in the municipal heat-and-power engineering. Power-and-resource-saving units and systems are becoming extremely urgent because of the power engineering crisis expansion. The self-adjusting heat supply system from the individual heating points with the heat-accumulating units and coil heat exchangers for independent heating and water supply systems has been examined. Coil heat exchangers are used in municipal heating for heat transfer (e.g. geothermal waters for the independent mains of the heating and hot water supply systems. The heat engineering calculation of the heating and accumulating unit with the coil heat exchanger for independent heat supply systems from individual heater was performed and experimental data were received at the experimental industrial unit under the laboratory conditions. The peculiarities of the flows in the intertubular space, their influence on the heat exchange and temperatures of the first and intermediate mains have been shown. It is important to know the processes running inside the apparatus to be able to improve the technical characteristics of the three-loop coil heat exchanger. The task solution will make it possible to save the materials consumption for the three-loop coil heat exchangers in the future

  18. Externally placed vs intravaginally positioned radio frequency coils for quantitative spin-spin relaxometry of ovarian follicular fluid

    International Nuclear Information System (INIS)

    Sarty, G.E.; Baerwald, A.R.; Loewy, J.; Pierson, R.A.

    2005-01-01

    To evaluate different imaging protocols, especially with respect to radio frequency (RF) receiver coil location, for Their suitability in providing least squares derived quantitative T 2 values of ovarian follicular fluid for investigations of basic ovarian physiology. Methods: The ovaries of 10 women were imaged via magnetic resonance imaging (MRI) using externally positioned and intravaginally placed RF receiver coils. Half-Fourier acquisition with single-shot turbo spin-echo (HASTE), multiple-echo T 2 , Dixon, turbo spin-echo, and 3-dimensional (3D) fast imaging with steady-state precession (FISP) and time-reversed FISP (PSIF) sequences were used. Quantitative T 2 nuclear spin relaxation rate information from the ovarian follicles between data acquired with the external and intravaginal coils were compared. Additionally, the amount of ovarian follicle and corpora lutea structural detail visible was qualitatively assessed. Results: The T 2 computations indicated that there was no difference in the follicular fluid T 2 values or in the heterogeneity (spatial variance) of the T 2 values between data acquired with the external RF coil and date acquired with the intravaginal RF coil. The best sequences for the visualization of ovarian internal structure were the 3D PSIF sequences and the multiple-echo T 2 -weighted images, confirming our earlier imaging work on excised cow ovaries. Conclusion: It is best to use an externally placed RF coil for quantitative MRI study of ovarian physiology given the lack of difference in quantitative T 2 information and the difficulty associated with imaging the ovaries using an intravaginal RF probe. (author)

  19. A flexible WLAN receiver

    NARCIS (Netherlands)

    Schiphorst, Roelof; Hoeksema, F.W.; Slump, Cornelis H.

    2003-01-01

    Flexible radio receivers are also called Software Defined Radios (SDRs) [1], [2]. The focus of our SDR project [3] is on designing the front end, from antenna to demodulation in bits, of a °exible, multi-standard WLAN receiver. We try to combine an instance of a (G)FSK receiver (Bluetooth) with an

  20. Mass and heat transfer at the outer surface of helical coils under single and two phase flow

    International Nuclear Information System (INIS)

    Abdel-Aziz, M.H.; Nirdosh, I.; Sedahmed, G.H.

    2016-01-01

    Highlights: • The work aims to develop reactors which need rapid temperature control. • Mass and heat transfer at the outer surface of helical coils was studied experimentally. • The experiments were conducted under gas sparing, single and two phase flow. • Variables were helical tube diameter, physical properties, and gas and liquid velocity. • Results verification in terms of natural convection and surface renewal mechanism was explained. - Abstract: The mass transfer behavior of the outer surface of vertical helical coil was studied by the electrochemical technique under single phase flow, gas sparging and two phase flow. Variables studied were helical tube diameter, physical properties of the solution, solution velocity and superficial gas velocity. The mass transfer data were correlated by dimensionless equations. Mass transfer enhancement ratio in case of two phase flow ranged from 1.1 to 4.9 compared to single phase flow. Implication of the results for the design and operation of helical coil reactors used to conduct L–S exothermic diffusion controlled reactions which need rapid temperature control were outlined. In this case the inner coil surface will act as a cooler while the outer surface will act a reaction surface. Immobilized enzyme catalyzed biochemical reactions where heat sensitive materials may be involved represent an example for the reactions which can employ the helical coil reactor. Also the importance of the results in the design of and operation of diffusion controlled membrane processes which employ helical coil membrane was noted. In view of the analogy between heat and mass transfer the possibility of using the results in the design and operation of helical coil heat exchangers was highlighted.