Smith, Gary
2015-01-01
Did you know that having a messy room will make you racist? Or that human beings possess the ability to postpone death until after important ceremonial occasions? Or that people live three to five years longer if they have positive initials, like ACE? All of these facts' have been argued with a straight face by researchers and backed up with reams of data and convincing statistics.As Nobel Prize-winning economist Ronald Coase once cynically observed, If you torture data long enough, it will confess.' Lying with statistics is a time-honoured con. In Standard Deviations, ec
Standard Deviation for Small Samples
Joarder, Anwar H.; Latif, Raja M.
2006-01-01
Neater representations for variance are given for small sample sizes, especially for 3 and 4. With these representations, variance can be calculated without a calculator if sample sizes are small and observations are integers, and an upper bound for the standard deviation is immediate. Accessible proofs of lower and upper bounds are presented for…
Comparison of estimators of standard deviation for hydrologic time series.
Tasker, Gary D.; Gilroy, E.J.
1982-01-01
Unbiasing factors as a function of serial correlation, rho, and sample size, n for the sample standard deviation of a lag one autoregressive model were generated by random number simulation. Monte Carlo experiments were used to compare the performance of several alternative methods for estimating the standard deviation sigma of a lag one autoregressive model in terms of bias, root mean square error, probability of underestimation, and expected opportunity design loss. -from Authors
The missing ingredient in effective-medium theories: Standard deviations
Bohren, Craig F; Lakhtakia, Akhlesh
2012-01-01
Effective-medium theories for electromagnetic constitutive parameters of particulate composite materials are theories of averages. Standard deviations are absent because of the lack of rigorous theories. But ensemble averages and standard deviations can be calculated from a rigorous theory of reflection by planar multilayers. Average reflectivities at all angles of incidence and two orthogonal polarization states for a multilayer composed of two kinds of electrically thin layers agree well with reflectivities for a single layer with the same overall thickness and a volume-weighted average of the relative permittivities of these two components. But the relative standard deviation can be appreciable depending on the angle of incidence and the polarization state of the incident illumination, and increases with increasing difference between the constitutive parameters of the two layers. This suggests that average constitutive parameters obtained from effective-medium theories do not have uniform validity for all ...
Estimation of amplitude and standard deviation of noisy sinusoidal signals
Juarez-Salazar, Rigoberto; Diaz-Ramirez, Victor H.
2017-01-01
A simple method to estimate the amplitude and standard deviation of sinusoidal signals corrupted with additive Gaussian noise is proposed. For this, a two-parameter model is developed by sorting the samples of the signal. This reduced parametric model allows robust parameter estimation, even if the phase function of the sinusoid is nonlinear, discontinuous, and unknown. The functionality and performance of the proposed method are analyzed by several computer simulations; the used GNU Octave program is provided. The proposed method can be useful for unbiased envelope estimation in fringe pattern normalization among other potential applications.
史海芳; 李树有; 姬永刚
2008-01-01
For two normal populations with u~nown means μi and variances σ2i>0,i=1,2,assume that there is a semi-order restriction between ratios of means and standard deviations and sample numbers of two normal populations are different.A procedure of obtaining the maximum likelihood estimatom of μi's and σ's under the semi-order restrictions is proposed.For i=3 case,some connected results and simulations are given.
New g-2 measurement deviates further from Standard Model
2004-01-01
"The latest result from an international collaboration of scientists investigating how the spin of a muon is affected as this type of subatomic particle moves through a magnetic field deviates further than previous measurements from theoretical predictions" (1 page).
Wang, Bin; Shi, Wenzhong; Miao, Zelang
2015-01-01
Standard deviational ellipse (SDE) has long served as a versatile GIS tool for delineating the geographic distribution of concerned features. This paper firstly summarizes two existing models of calculating SDE, and then proposes a novel approach to constructing the same SDE based on spectral decomposition of the sample covariance, by which the SDE concept is naturally generalized into higher dimensional Euclidean space, named standard deviational hyper-ellipsoid (SDHE). Then, rigorous recursion formulas are derived for calculating the confidence levels of scaled SDHE with arbitrary magnification ratios in any dimensional space. Besides, an inexact-newton method based iterative algorithm is also proposed for solving the corresponding magnification ratio of a scaled SDHE when the confidence probability and space dimensionality are pre-specified. These results provide an efficient manner to supersede the traditional table lookup of tabulated chi-square distribution. Finally, synthetic data is employed to generate the 1-3 multiple SDEs and SDHEs. And exploratory analysis by means of SDEs and SDHEs are also conducted for measuring the spread concentrations of Hong Kong's H1N1 in 2009.
Bin Wang
Full Text Available Standard deviational ellipse (SDE has long served as a versatile GIS tool for delineating the geographic distribution of concerned features. This paper firstly summarizes two existing models of calculating SDE, and then proposes a novel approach to constructing the same SDE based on spectral decomposition of the sample covariance, by which the SDE concept is naturally generalized into higher dimensional Euclidean space, named standard deviational hyper-ellipsoid (SDHE. Then, rigorous recursion formulas are derived for calculating the confidence levels of scaled SDHE with arbitrary magnification ratios in any dimensional space. Besides, an inexact-newton method based iterative algorithm is also proposed for solving the corresponding magnification ratio of a scaled SDHE when the confidence probability and space dimensionality are pre-specified. These results provide an efficient manner to supersede the traditional table lookup of tabulated chi-square distribution. Finally, synthetic data is employed to generate the 1-3 multiple SDEs and SDHEs. And exploratory analysis by means of SDEs and SDHEs are also conducted for measuring the spread concentrations of Hong Kong's H1N1 in 2009.
Timothy J. Fullman; Erin L. Bunting
2014-01-01
Northern Botswana is influenced by various socio-ecological drivers of landscape change. The African elephant ( Loxodonta africana ) is one of the leading sources of landscape shifts in this region. Developing the ability to assess elephant impacts on savanna vegetation is important to promote effective management strategies. The Moving Standard Deviation Index (MSDI) applies a standard deviation calculation to remote sensing imagery to assess degradation of vegetation. Used previously for as...
Set standard deviation, repeatability and offset of absolute gravimeter A10-008
Schmerge, D.; Francis, O.
2006-01-01
The set standard deviation, repeatability and offset of absolute gravimeter A10-008 were assessed at the Walferdange Underground Laboratory for Geodynamics (WULG) in Luxembourg. Analysis of the data indicates that the instrument performed within the specifications of the manufacturer. For A10-008, the average set standard deviation was (1.6 0.6) ??Gal (1Gal ??? 1 cm s -2), the average repeatability was (2.9 1.5) ??Gal, and the average offset compared to absolute gravimeter FG5-216 was (3.2 3.5) ??Gal. ?? 2006 BIPM and IOP Publishing Ltd.
American Society for Testing and Materials. Philadelphia
2009-01-01
1.1 This photographic practice determines the optical distortion and deviation of a line of sight through a simple transparent part, such as a commercial aircraft windshield or a cabin window. This practice applies to essentially flat or nearly flat parts and may not be suitable for highly curved materials. 1.2 Test Method F 801 addresses optical deviation (angluar deviation) and Test Method F 2156 addresses optical distortion using grid line slope. These test methods should be used instead of Practice F 733 whenever practical. 1.3 This standard does not purport to address the safety concerns associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.
Use of Standard Deviations as Predictors in Models Using Large-Scale International Data Sets
Austin, Bruce; French, Brian; Adesope, Olusola; Gotch, Chad
2017-01-01
Measures of variability are successfully used in predictive modeling in research areas outside of education. This study examined how standard deviations can be used to address research questions not easily addressed using traditional measures such as group means based on index variables. Student survey data were obtained from the Organisation for…
Deviating from the standard: effects on labor continuity and career patterns
Roman, A.A.
2006-01-01
Deviating from a standard career path is increasingly becoming an option for individuals to combine paid labor with other important life domains. These career detours emerge in diverse labor forms such as part-time jobs, temporary working hour reductions, and labor force time-outs, used to alleviate
Modeling of pharmaceuticals mixtures toxicity with deviation ratio and best-fit functions models.
Wieczerzak, Monika; Kudłak, Błażej; Yotova, Galina; Nedyalkova, Miroslava; Tsakovski, Stefan; Simeonov, Vasil; Namieśnik, Jacek
2016-11-15
The present study deals with assessment of ecotoxicological parameters of 9 drugs (diclofenac (sodium salt), oxytetracycline hydrochloride, fluoxetine hydrochloride, chloramphenicol, ketoprofen, progesterone, estrone, androstenedione and gemfibrozil), present in the environmental compartments at specific concentration levels, and their mutual combinations by couples against Microtox® and XenoScreen YES/YAS® bioassays. As the quantitative assessment of ecotoxicity of drug mixtures is an complex and sophisticated topic in the present study we have used two major approaches to gain specific information on the mutual impact of two separate drugs present in a mixture. The first approach is well documented in many toxicological studies and follows the procedure for assessing three types of models, namely concentration addition (CA), independent action (IA) and simple interaction (SI) by calculation of a model deviation ratio (MDR) for each one of the experiments carried out. The second approach used was based on the assumption that the mutual impact in each mixture of two drugs could be described by a best-fit model function with calculation of weight (regression coefficient or other model parameter) for each of the participants in the mixture or by correlation analysis. It was shown that the sign and the absolute value of the weight or the correlation coefficient could be a reliable measure for the impact of either drug A on drug B or, vice versa, of B on A. Results of studies justify the statement, that both of the approaches show similar assessment of the mode of mutual interaction of the drugs studied. It was found that most of the drug mixtures exhibit independent action and quite few of the mixtures show synergic or dependent action. Copyright © 2016. Published by Elsevier B.V.
Using Spectral Flux Ratios to Standardize SN Ia Luminosities
Bailey, S; Antilogus, P; Aragon, C; Baltay, C; Bongard, S; Buton, C; Childress, M; Chotard, N; Copin, Y; Gangler, E; Loken, S; Nugent, P; Pain, R; Pécontal, E; Pereira, R; Perlmutter, S; Rabinowitz, D; Rigaudier, G; Runge, K; Scalzo, R; Smadja, G; Swift, H; Tao, C; Thomas, R C; Wu, C
2009-01-01
We present a new method to standardize Type Ia supernova (SN Ia) luminosities to ~<0.13 magnitudes using flux ratios from a single flux-calibrated spectrum per SN. Using Nearby Supernova Factory spectrophotomery of 58 SNe Ia, we performed an unbiased search for flux ratios which correlate with SN Ia luminosity. After developing the method and selecting the best ratios from a training sample, we verified the results on a separate validation sample and with data from the literature. We identified multiple flux ratios whose correlations with luminosity are stronger than those of light curve shape and color, previously identified spectral feature ratios, or equivalent width measurements. In particular, the flux ratio R(642/443) = F(642 nm) / F(443 nm) has a correlation of 0.95 with SN Ia absolute magnitudes. Using this single ratio as a correction factor produces a Hubble diagram with a residual scatter standard deviation of 0.125 +- 0.011 mag, compared with 0.161 +- 0.015 mag when fit with the SALT2 light cur...
Isolating the Systematic Component of a Single Stock’s (or Portfolio’s) Standard Deviation
Cara Marshall
2008-01-01
This paper revisits the roots of modern portfolio theory and the recognition that a stock’s (or a stock portfolio’s) risk can be decomposed into a systematic component and an unsystematic component, and, further, that only the former should contribute to expected return. However, instead of isolating the systematic component of risk by recasting the risk in terms of a stock’s beta coefficient, I choose to decompose the standard deviation, or variance if one prefers the original risk measure, ...
National Oceanic and Atmospheric Administration, Department of Commerce — Standard deviation of depth was calculated from the bathymetry surface for each cell using the ArcGIS Spatial Analyst Focal Statistics "STD" parameter. Standard...
Timothy J. Fullman
2014-01-01
Full Text Available Northern Botswana is influenced by various socio-ecological drivers of landscape change. The African elephant (Loxodonta africana is one of the leading sources of landscape shifts in this region. Developing the ability to assess elephant impacts on savanna vegetation is important to promote effective management strategies. The Moving Standard Deviation Index (MSDI applies a standard deviation calculation to remote sensing imagery to assess degradation of vegetation. Used previously for assessing impacts of livestock on rangelands, we evaluate the ability of the MSDI to detect elephant-modified vegetation along the Chobe riverfront in Botswana, a heavily elephant-impacted landscape. At broad scales, MSDI values are positively related to elephant utilization. At finer scales, using data from 257 sites along the riverfront, MSDI values show a consistent negative relationship with intensity of elephant utilization. We suggest that these differences are due to varying effects of elephants across scales. Elephant utilization of vegetation may increase heterogeneity across the landscape, but decrease it within heavily used patches, resulting in the observed MSDI pattern of divergent trends at different scales. While significant, the low explanatory power of the relationship between the MSDI and elephant utilization suggests the MSDI may have limited use for regional monitoring of elephant impacts.
A standard deviation selection in evolutionary algorithm for grouper fish feed formulation
Cai-Juan, Soong; Ramli, Razamin; Rahman, Rosshairy Abdul
2016-10-01
Malaysia is one of the major producer countries for fishery production due to its location in the equatorial environment. Grouper fish is one of the potential markets in contributing to the income of the country due to its desirable taste, high demand and high price. However, the demand of grouper fish is still insufficient from the wild catch. Therefore, there is a need to farm grouper fish to cater to the market demand. In order to farm grouper fish, there is a need to have prior knowledge of the proper nutrients needed because there is no exact data available. Therefore, in this study, primary data and secondary data are collected even though there is a limitation of related papers and 30 samples are investigated by using standard deviation selection in Evolutionary algorithm. Thus, this study would unlock frontiers for an extensive research in respect of grouper fish feed formulation. Results shown that the fitness of standard deviation selection in evolutionary algorithm is applicable. The feasible and low fitness, quick solution can be obtained. These fitness can be further predicted to minimize cost in farming grouper fish.
Zagoris Konstantinos
2011-01-01
Full Text Available Abstract A text localization technique is required to successfully exploit document images such as technical articles and letters. The proposed method detects and extracts text areas from document images. Initially a connected components analysis technique detects blocks of foreground objects. Then, a descriptor that consists of a set of suitable document structure elements is extracted from the blocks. This is achieved by incorporating an algorithm called Standard Deviation Analysis of Structure Elements (SDASE which maximizes the separability between the blocks. Another feature of the SDASE is that its length adapts according to the requirements of the application. Finally, the descriptor of each block is used as input to a trained support vector machines that classify the block as text or not. The proposed technique is also capable of adjusting to the text structure of the documents. Experimental results on benchmarking databases demonstrate the effectiveness of the proposed method.
Xu Meng-Long; Yang Chang-Bao; Wu Yan-Gang; Chen Jing-Yi; Huan Heng-Fei
2015-01-01
Most edge-detection methods rely on calculating gradient derivatives of the potential field, a process that is easily affected by noise and is therefore of low stability. We propose a new edge-detection method named correlation coeffi cient of multidirectional standard deviations (CCMS) that is solely based on statistics. First, we prove the reliability of the proposed method using a single model and then a combination of models. The proposed method is evaluated by comparing the results with those obtained by other edge-detection methods. The CCMS method offers outstanding recognition, retains the sharpness of details, and has low sensitivity to noise. We also applied the CCMS method to Bouguer anomaly data of a potash deposit in Laos. The applicability of the CCMS method is shown by comparing the inferred tectonic framework to that inferred from remote sensing (RS) data.
Muon’s (g-2): the obstinate deviation from the Standard Model
Antonella Del Rosso
2011-01-01
It’s been 50 years since a small group at CERN measured the muon (g-2) for the first time. Several other experiments have followed over the years. The latest measurement at Brookhaven (2004) gave a value that obstinately remains about 3 standard deviations away from the prediction of the Standard Model. Francis Farley, one of the fathers of the (g-2) experiments, argues that a statement such as “everything we observe is accounted for by the Standard Model” is not acceptable. Francis J. M. Farley. Francis J. M. Farley, Fellow of the Royal Society since 1972 and the 1980 winner of the Hughes Medal "for his ultra-precise measurements of the muon magnetic moment, a severe test of quantum electrodynamics and of the nature of the muon", is among the scientists who still look at the (g-2) anomaly as one of the first proofs of the existence of new physics. “Although it seems to be generally believed that all experiments agree with the Stan...
Veissid, N. (Instituto de Pesquisas Espaciais, Sao Jose dos Campos (Brazil)); Cruz, M.T.F. da (Universidade de Sao Paulo, SP (Brazil). Inst. de Fisica); Andrade, A.M. de (Universidade de Sao Paulo, SP (Brazil). Lab. de Microeletronica)
1990-05-01
A method for the determination of the standard deviations of the solar cell characteristic curve fitting parameters is presented for the first time. In this method, a Taylor series expansion of the parameters, around their best values, is made resulting in linear functions which permit the determination of the standard deviations with the least-squares method. The parameters, with the respective standard deviations, were determined from the experimental I-V characteristic curves obtained under illuminated and dark conditions. For the studied experimental I-V curves, the diode saturation currents, the diode factor and the shunt resistance showed smaller standard deviations in the dark condition, and the series resistance appeared to be more precise in the illuminated I-V characteristic. (orig.).
Reyes, Melissa Lopez
2003-01-01
A structure for learning the connections among standard deviations, z-scores, and normal distributions is presented. The components of this structure are classified into intuitive or previously learned conceptual knowledge, computational knowledge, and formalized conceptual knowledge. (Contains 1 figure.)
Y. Song; Z. Gui; H. Wu; Y. Wei
2017-01-01
.... The framework uses standard deviational ellipse (SDE) and shifting route of gravity centers to show the spatial distribution and yearly developing trends of different enterprise types according to their industry categories...
Reyes, Melissa Lopez
2003-01-01
A structure for learning the connections among standard deviations, z-scores, and normal distributions is presented. The components of this structure are classified into intuitive or previously learned conceptual knowledge, computational knowledge, and formalized conceptual knowledge. (Contains 1 figure.)
Scatter-Reducing Sounding Filtration Using a Genetic Algorithm and Mean Monthly Standard Deviation
Mandrake, Lukas
2013-01-01
Retrieval algorithms like that used by the Orbiting Carbon Observatory (OCO)-2 mission generate massive quantities of data of varying quality and reliability. A computationally efficient, simple method of labeling problematic datapoints or predicting soundings that will fail is required for basic operation, given that only 6% of the retrieved data may be operationally processed. This method automatically obtains a filter designed to reduce scatter based on a small number of input features. Most machine-learning filter construction algorithms attempt to predict error in the CO2 value. By using a surrogate goal of Mean Monthly STDEV, the goal is to reduce the retrieved CO2 scatter rather than solving the harder problem of reducing CO2 error. This lends itself to improved interpretability and performance. This software reduces the scatter of retrieved CO2 values globally based on a minimum number of input features. It can be used as a prefilter to reduce the number of soundings requested, or as a post-filter to label data quality. The use of the MMS (Mean Monthly Standard deviation) provides a much cleaner, clearer filter than the standard ABS(CO2-truth) metrics previously employed by competitor methods. The software's main strength lies in a clearer (i.e., fewer features required) filter that more efficiently reduces scatter in retrieved CO2 rather than focusing on the more complex (and easily removed) bias issues.
Edjabou, Maklawe Essonanawe; Martín-Fernández, Josep Antoni; Scheutz, Charlotte; Astrup, Thomas Fruergaard
2017-09-04
Data for fractional solid waste composition provide relative magnitudes of individual waste fractions, the percentages of which always sum to 100, thereby connecting them intrinsically. Due to this sum constraint, waste composition data represent closed data, and their interpretation and analysis require statistical methods, other than classical statistics that are suitable only for non-constrained data such as absolute values. However, the closed characteristics of waste composition data are often ignored when analysed. The results of this study showed, for example, that unavoidable animal-derived food waste amounted to 2.21±3.12% with a confidence interval of (-4.03; 8.45), which highlights the problem of the biased negative proportions. A Pearson's correlation test, applied to waste fraction generation (kg mass), indicated a positive correlation between avoidable vegetable food waste and plastic packaging. However, correlation tests applied to waste fraction compositions (percentage values) showed a negative association in this regard, thus demonstrating that statistical analyses applied to compositional waste fraction data, without addressing the closed characteristics of these data, have the potential to generate spurious or misleading results. Therefore, ¨compositional data should be transformed adequately prior to any statistical analysis, such as computing mean, standard deviation and correlation coefficients. Copyright © 2017 Elsevier Ltd. All rights reserved.
A better detection of 2LSB steganography via standard deviation of the extended pairs of values
Khalind, Omed; Aziz, Benjamin
2015-05-01
This paper proposes a modification to the Extended Pairs of Values (EPoV) method of 2LSB steganalysis in digital still images. In EPoV, the detection and the estimation of the hidden message length were performed in two separate processes as it considered the automated detection. However, the new proposed method uses the standard deviation of the EPoV to measure the amount of distortion in the stego image made by the embedding process using 2LSB replacement, which is directly proportional with the embedding rate. It is shown that it can accurately estimate the length of the hidden message and outperform the other methods of the targeted 2LSB steganalysis in the literature. The proposed method is also more consistent with the steganalysis methods in the literature by giving the amount of difference to the expected clean image. According to the experimental results, based on analysing 3000 nevercompressed images, the proposed method is more accurate than the current targeted 2LSB steganalysis methods for low embedding rates.
Falabino, Simona; Trini Castelli, Silvia
2017-02-01
In air quality practice, observed data are often input to air pollution models to simulate the pollutants dispersion and to estimate their concentration. When the area of interest includes urban sites, observed data collected at urban or suburban stations can be available, and it can happen to use them for estimating surface layer parameters given in input to the models. In such case, roughness sublayer quantities may enter the parameterizations of the turbulence variables as if they were representative of the inertial sublayer, possibly leading to a not appropriate application of the Monin-Obukhov similarity theory. We investigate whether it is possible to derive suitable values of the wind velocity standard deviations for the inertial sublayer using the friction velocity and stability parameter observed in the roughness sublayer, inside a similarity-like analytical function. For this purpose, an analysis of sonic anemometer data sets collected in suburban and urban sites is proposed. The values derived through this approach are compared to actual observations in the inertial sublayer. The transferability of the empirical coefficients estimated for the similarity functions between different sites, characterized by similar or different morphologies, is also addressed. The derived functions proved to be a reasonable approximation of the actual data. This method was found to be feasible and generally reliable, and can be a reference to keep using, in air pollution models, the similarity theory parameterizations when measurements are available only in the roughness sublayer.
Berendes, Todd A.; Mecikalski, John R.; MacKenzie, Wayne M.; Bedka, Kristopher M.; Nair, U. S.
2008-10-01
This paper describes a statistical clustering approach toward the classification of cloud types within meteorological satellite imagery, specifically, visible and infrared data. The method is based on the Standard Deviation Limited Adaptive Clustering (SDLAC) procedure, which has been used to classify a variety of features within both polar orbiting and geostationary imagery, including land cover, volcanic ash, dust, and clouds of various types. In this study, the focus is on classifying cumulus clouds of various types (e.g., "fair weather, "towering, and newly glaciated cumulus, in addition to cumulonimbus). The SDLAC algorithm is demonstrated by showing examples using Geostationary Operational Environmental Satellite (GOES) 12, Meteosat Second Generation's (MSG) Spinning Enhanced Visible and Infrared Imager (SEVIRI), and the Moderate Resolution Infrared Spectrometer (MODIS). Results indicate that the method performs well, classifying cumulus similarly between MODIS, SEVIRI, and GOES, despite the obvious channel and resolution differences between these three sensors. The SDLAC methodology has been used in several research activities related to convective weather forecasting, which offers some proof of concept for its value.
Shahzad, Aamer; Tian, Fang-Bao; Young, John; Lai, Joseph C. S.
2016-11-01
This numerical study is focused on assessing the effect on the aerodynamic hovering performance of wing shapes defined by the radius of the first moment of the wing area ( r 1 ¯ ) and aspect ratio (AR). In addition, the effect of introducing a deviation angle in the kinematics is examined. The performance of r 1 ¯ = 0 . 43 , 0.53, and 0.63 wings with AR of 1.5, 2.96, 4.5, and 6.0 is investigated at Reynolds numbers (Re) = 12, 400, and 13 500. The performance trends of the wing shapes have been observed to be independent of Re for both 2-angle and 3-angle kinematics. This is because high suction pressures associated with the leading-edge vortex are predominantly spread in the distal (away from the wing root) and leeward regions (towards the trailing-edge) of high flapping velocities for all the cases. While the deviation angle is detrimental to the production of lift and power economy (PE, defined as the ratio of the mean lift coefficient to the mean aerodynamic power coefficient) at Re = 12 due to strong viscous effects, it improves PE at Re = 400 and 13 500. A high instantaneous angle of attack at the stroke reversal results in high lift peak for 3-angle kinematics but its effect at Re = 400 and 13 500 is attenuated by strong vortical structures on the underside of the wing. Maximum PE is achieved at AR = 2.96, as a low AR wing does not produce enough lift and high AR wings consume more aerodynamic power. Although the lift is maximized using high r 1 ¯ and AR wings, our results show that low r 1 ¯ and high AR wings are best for maximizing PE for a given lift in insects.
Encarnación Álvarez
2015-07-01
Full Text Available Statistical quality control (SQC is used by companies and industries for many reasons. For example, the process capability of machines is an important aspect of SQC, which consists in evaluating the ability of a production process to perform with the required specifications. In other words, the process capability measures the ability of a process of producing acceptable products according to the established specifications. The most common indicator used to measure the process capability is the process capability index, which depends on the process standard deviation. In practice, the standard deviation is unknown, and the process capability index is thus estimated by using an estimator of the process standard deviation. In this paper, we describe the most common estimators of the process standard deviation, and define the corresponding estimators of the process capability index. A bound for the bias ratio of the various estimators is obtained. Monte Carlo simulation studies are carried out to analyze the empirical performance of the various estimators of the process capability index. Empirical results indicate that biases can be obtained, specially in the presence of small samples. We also observe that the estimators of the process capability index based on sample ranges are less accurate than the alternative estimators.
ESRD QIP - Standardized Readmission Ratio - Payment Year 2017
U.S. Department of Health & Human Services — ESRD QIP â Standardized Readmission Ratio â Payment Year 2017 Lists standardized readmission data used by ESRD QIP to assess dialysis facility performance.
Joustra, S.D.; Plas, E.M. van der; Goede, J.; Oostdijk, W.; Delemarre-van de Waal, H.A.; Hack, W.W.M.; Buuren, S. van; Wit, J.M.
2015-01-01
Aim Accurate calculations of testicular volume standard deviation (SD) scores are not currently available. We constructed LMS-smoothed age-reference charts for testicular volume in healthy boys. Methods The LMS method was used to calculate reference data, based on testicular volumes from ultrasonogr
S.N. Danilchenko
2014-04-01
Full Text Available The causes of Са / Р ratio deviation in biological apatites from stoichiometric one were discussed. By the simple model evaluation Са / Р ratio was shown to deviate from stoichiometric one because of small sizes of crystals, and peculiarities in chemical composition of their facets. Also size effect is noted to be unsufficient for explanation of wide variations of Са / Р ratio in biological apatites. It proves the significant contribution of lattice isovalent and heterovalent substitution into variability of Са / Р ratio. The problem of revealing the predominant causes of Са / Р deviation from stoichiometric one and estimation of their relative contribution is related to determination of the functional role of the structural imperfections in biological apatites of different origin.
Nelde, Peter H.
1974-01-01
Concludes that the German used in the east Belgium newspaper differs fr om standard High German. Proceeds to list these differences in the areas of lexicology, semantics and stylistics, morphology and syntax, orthography e tc. (Text is in German.) (DS)
75 FR 67093 - Iceberg Water Deviating From Identity Standard; Temporary Permit for Market Testing
2010-11-01
...), Canada J3Z 1G4. This permit covers limited interstate marketing tests of products identified as ``GLACE... requirements of the standard with the exception of the source definition. The purpose of this temporary permit... problems, and assess commercial feasibility. This permit provides for the temporary marketing of...
SNR and Standard Deviation of cGNSS-R and iGNSS-R Scatterometric Measurements.
Alonso-Arroyo, Alberto; Querol, Jorge; Lopez-Martinez, Carlos; Zavorotny, Valery U; Park, Hyuk; Pascual, Daniel; Onrubia, Raul; Camps, Adriano
2017-01-19
This work addresses the accuracy of the Global Navigation Satellite Systems (GNSS)-Reflectometry (GNSS-R) scatterometric measurements considering the presence of both coherent and incoherent scattered components, for both conventional GNSS-R (cGNSS-R) and interferometric GNSS-R (iGNSS-R) techniques. The coherent component is present for some type of surfaces, and it has been neglected until now because it vanishes for the sea surface scattering case. Taking into account the presence of both scattering components, the estimated Signal-to-Noise Ratio (SNR) for both techniques is computed based on the detectability criterion, as it is done in conventional GNSS applications. The non-coherent averaging operation is considered from a general point of view, taking into account that thermal noise contributions can be reduced by an extra factor of 0.88 dB when using partially overlapped or partially correlated samples. After the SNRs are derived, the received waveform's peak variability is computed, which determines the system's capability to measure geophysical parameters. This theoretical derivations are applied to the United Kingdom (UK) TechDemoSat-1 (UK TDS-1) and to the future GNSS REflectometry, Radio Occultation and Scatterometry on board the International Space Station (ISS) (GEROS-ISS) scenarios, in order to estimate the expected scatterometric performance of both missions.
SNR and Standard Deviation of cGNSS-R and iGNSS-R Scatterometric Measurements
Alberto Alonso-Arroyo
2017-01-01
Full Text Available This work addresses the accuracy of the Global Navigation Satellite Systems (GNSS-Reflectometry (GNSS-R scatterometric measurements considering the presence of both coherent and incoherent scattered components, for both conventional GNSS-R (cGNSS-R and interferometric GNSS-R (iGNSS-R techniques. The coherent component is present for some type of surfaces, and it has been neglected until now because it vanishes for the sea surface scattering case. Taking into account the presence of both scattering components, the estimated Signal-to-Noise Ratio (SNR for both techniques is computed based on the detectability criterion, as it is done in conventional GNSS applications. The non-coherent averaging operation is considered from a general point of view, taking into account that thermal noise contributions can be reduced by an extra factor of 0.88 dB when using partially overlapped or partially correlated samples. After the SNRs are derived, the received waveform’s peak variability is computed, which determines the system’s capability to measure geophysical parameters. This theoretical derivations are applied to the United Kingdom (UK TechDemoSat-1 (UK TDS-1 and to the future GNSS REflectometry, Radio Occultation and Scatterometry on board the International Space Station (ISS (GEROS-ISS scenarios, in order to estimate the expected scatterometric performance of both missions.
42 CFR 403.215 - Loss ratio standards.
2010-10-01
... 42 Public Health 2 2010-10-01 2010-10-01 false Loss ratio standards. 403.215 Section 403.215 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL... of solicitation of individuals through the mail or by mass media advertising are...
Kang, Namgoo; Jung, Min-Ho; Jeong, Hyun-Cheol; Lee, Yung-Seop
2015-06-01
The general sample standard deviation and the Monte-Carlo methods as an estimate of confidence interval is frequently being used for estimates of uncertainties with regard to greenhouse gas emission, based on the critical assumption that a given data set follows a normal (Gaussian) or statistically known probability distribution. However, uncertainty estimated using those methods are severely limited in practical applications where it is challenging to assume the probability distribution of a data set or where the real data distribution form appears to deviate significantly from statistically known probability distribution models. In order to solve these issues encountered especially in reasonable estimation of uncertainty about the average of greenhouse gas emission, we present two statistical methods, the pooled standard deviation method (PSDM) and the standardized-t bootstrap method (STBM) based upon statistical theories. We also report interesting results of the uncertainties about the average of a data set of methane (CH4) emission from rice cultivation under the four different irrigation conditions in Korea, measured by gas sampling and subsequent gas analysis. Results from the applications of the PSDM and the STBM to these rice cultivation methane emission data sets clearly demonstrate that the uncertainties estimated by the PSDM were significantly smaller than those by the STBM. We found that the PSDM needs to be adopted in many cases where a data probability distribution form appears to follow an assumed normal distribution with both spatial and temporal variations taken into account. However, the STBM is a more appropriate method widely applicable to practical situations where it is realistically impossible with the given data set to reasonably assume or determine a probability distribution model with a data set showing evidence of fairly asymmetric distribution but severely deviating from known probability distribution models.
Osmar Abílio de Carvalho Júnior
2015-05-01
Full Text Available Typically, digital image processing for burned-areas detection combines the use of a spectral index and the seasonal differencing method. However, the seasonal differencing has many errors when applied to a long-term time series. This article aims to develop and test two methods as an alternative to the traditional seasonal difference. The study area is the Chapada dos Veadeiros National Park (Central Brazil that comprises different vegetation of the Cerrado biome. We used the MODIS/Terra Surface Reflectance 8-Day composite data, considering a 12-year period. The normalized burn ratio was calculated from the band 2 (250-meter resolution and the band 7 (500-meter resolution reasampled to 250-meter. In this context, the normalization methods aim to eliminate all possible sources of spectral variation and highlight the burned-area features. The proposed normalization methods were the standardized time-series and the interannual phenological deviation. The standardized time-series calculate for each pixel the z-scores of its temporal curve, obtaining a mean of 0 and a standard deviation of 1. The second method establishes a reference curve for each pixel from the average interannual phenology that is subtracted for every year of its respective time series. Optimal threshold value between burned and unburned area for each method was determined from accuracy assessment curves, which compare different threshold values and its accuracy indices with a reference classification using Landsat TM. The different methods have similar accuracy for the burning event, where the standardized method has slightly better results. However, the seasonal difference method has a very false positive error, especially in the period between the rainy and dry seasons. The interannual phenological deviation method minimizes false positive errors, but some remain. In contrast, the standardized time series shows excellent results not containing this type of error. This
Similar tests and the standardized log likelihood ratio statistic
Jensen, Jens Ledet
1986-01-01
When testing an affine hypothesis in an exponential family the 'ideal' procedure is to calculate the exact similar test, or an approximation to this, based on the conditional distribution given the minimal sufficient statistic under the null hypothesis. By contrast to this there is a 'primitive......' approach in which the marginal distribution of a test statistic considered and any nuisance parameter appearing in the test statistic is replaced by an estimate. We show here that when using standardized likelihood ratio statistics the 'primitive' procedure is in fact an 'ideal' procedure to order O(n -3...
Tscherning, Carl Christian
2015-01-01
The method of Least-Squares Collocation (LSC) may be used for the modeling of the anomalous gravity potential (T) and for the computation (prediction) of quantities related to T by a linear functional. Errors may also be estimated. However, when using an isotropic covariance function or equivalen...... on gravity anomalies (at 10 km altitude) predicted from GOCE Tzz. This has given an improved agreement between errors based on the differences between values derived from EGM2008 (to degree 512) and predicted gravity anomalies.......The method of Least-Squares Collocation (LSC) may be used for the modeling of the anomalous gravity potential (T) and for the computation (prediction) of quantities related to T by a linear functional. Errors may also be estimated. However, when using an isotropic covariance function or equivalent...... outside the data area. On the other hand, a comparison of predicted quantities with observed values show that the error also varies depending on the local data standard deviation. This quantity may be (and has been) estimated using the GOCE second order vertical derivative, Tzz, in the area covered...
Y. Song
2017-09-01
Full Text Available Analysing spatiotemporal distribution patterns and its dynamics of different industries can help us learn the macro-level developing trends of those industries, and in turn provides references for industrial spatial planning. However, the analysis process is challenging task which requires an easy-to-understand information presentation mechanism and a powerful computational technology to support the visual analytics of big data on the fly. Due to this reason, this research proposes a web-based framework to enable such a visual analytics requirement. The framework uses standard deviational ellipse (SDE and shifting route of gravity centers to show the spatial distribution and yearly developing trends of different enterprise types according to their industry categories. The calculation of gravity centers and ellipses is paralleled using Apache Spark to accelerate the processing. In the experiments, we use the enterprise registration dataset in Mainland China from year 1960 to 2015 that contains fine-grain location information (i.e., coordinates of each individual enterprise to demonstrate the feasibility of this framework. The experiment result shows that the developed visual analytics method is helpful to understand the multi-level patterns and developing trends of different industries in China. Moreover, the proposed framework can be used to analyse any nature and social spatiotemporal point process with large data volume, such as crime and disease.
Song, Y.; Gui, Z.; Wu, H.; Wei, Y.
2017-09-01
Analysing spatiotemporal distribution patterns and its dynamics of different industries can help us learn the macro-level developing trends of those industries, and in turn provides references for industrial spatial planning. However, the analysis process is challenging task which requires an easy-to-understand information presentation mechanism and a powerful computational technology to support the visual analytics of big data on the fly. Due to this reason, this research proposes a web-based framework to enable such a visual analytics requirement. The framework uses standard deviational ellipse (SDE) and shifting route of gravity centers to show the spatial distribution and yearly developing trends of different enterprise types according to their industry categories. The calculation of gravity centers and ellipses is paralleled using Apache Spark to accelerate the processing. In the experiments, we use the enterprise registration dataset in Mainland China from year 1960 to 2015 that contains fine-grain location information (i.e., coordinates of each individual enterprise) to demonstrate the feasibility of this framework. The experiment result shows that the developed visual analytics method is helpful to understand the multi-level patterns and developing trends of different industries in China. Moreover, the proposed framework can be used to analyse any nature and social spatiotemporal point process with large data volume, such as crime and disease.
Optimal reinsurance under the standard deviation principle%标准差准则下的最优再保险
宋立新; 黄玉洁; 周娟
2011-01-01
本文关注的是在标准差准则下如何进行再保险,使得保险公司和再保险公司的风险波动达到最小.在容许合约类范围内得到了建立最优再保险合约的充分条件.如果再保险公司的风险小于一个给定阈值,我们找到了使保险公司的风险最小的最优再保险合约.在这里,保险公司可以采取三种最一般且有效的风险措施.%This paper concerns how to purchase the reinsurance to minimize both the insurer and the reinsurer's risk fluctuation under the standard deviation principle. Sufficient conditions for the optimal reinsurance contract are obtained in the restricted class of admissible contracts. Assume that the reinsurer's risk is less than a threshold, and then we find out the optimal reinsurance contract that minimizes the insurer's risk. Here the insurer company can take three general and useful risk measures.
Negative Control Outcomes and the Analysis of Standardized Mortality Ratios.
Richardson, David B; Keil, Alexander P; Tchetgen Tchetgen, Eric; Cooper, Glinda
2015-09-01
In occupational cohort mortality studies, epidemiologists often compare the observed number of deaths in the cohort to the expected number obtained by multiplying person-time accrued in the study cohort by the mortality rate in an external reference population. Interpretation of the result may be difficult due to noncomparability of the occupational cohort and reference population with respect to unmeasured risk factors for the outcome of interest. We describe an approach to estimate an adjusted standardized mortality ratio (aSMR) to control for such bias. The approach draws on methods developed for the use of negative control outcomes. Conditions necessary for unbiased estimation are described, as well as looser conditions necessary for bias reduction. The approach is illustrated using data on bladder cancer mortality among male Oak Ridge National Laboratory workers. The SMR for bladder cancer was elevated among hourly-paid males (SMR = 1.9; 95% confidence interval [CI] = 1.3, 2.7) but not among monthly-paid males (SMR = 1.0; 95% CI = 0.67, 1.3). After indirect adjustment using the proposed approach, the mortality ratios were similar in magnitude among hourly- and monthly-paid men (aSMR = 2.2; 95% CI = 1.5, 3.2; and, aSMR = 2.0; 95% CI = 1.4, 2.8, respectively). The proposed adjusted SMR offers a complement to typical SMR analyses.
Martya Rahmaniati
2014-06-01
Full Text Available Dengue Fever Disease is still regarded as an endemic disease in Banjar City. Information is still required to map dengue fever case distribution, mean center of case distribution, and the direction of dengue fever case dispersion in order to support the surveillance program in the relation to the vast area of the dengue fever disease control program. The objective of the research is to obtain information regarding the area of dengue fever disease distribution in Banjar City by utilizing the Standard Deviational Ellipse (SDE model. The research is an observational study with Explanatory Spatial Data Analysis (ESDA. Data analysis uses SDE model with the scope of the entire sub district area in Banjar City. The data analyzed is dengue fever case from 2007-2013 periods, with the number of sample of 315 cases. Social demographic overview of dengue fever patients in Banjar City shows that most of the patients are within the productive age, with 39.7% within the school age and 45.7% are within the work age. Most of the dengue fever patients are men (58.1%. Distribution of dengue fever cases from the period of 2007 until 2012 mostly occur in 25-37.5 meters above sea level (MASL (55.8%. The SDE models of dengue fever cases in Banjar City generally form dispersion patterns following the x-axis and clustered by physiographic boundaries. The SDE model can be used to discover dispersion patterns and directions of dengue fever cases, therefore, dengue fever disease control program can be conducted based on local-specific information, in order to support health decision.
Varadhan, S R S
2016-01-01
The theory of large deviations deals with rates at which probabilities of certain events decay as a natural parameter in the problem varies. This book, which is based on a graduate course on large deviations at the Courant Institute, focuses on three concrete sets of examples: (i) diffusions with small noise and the exit problem, (ii) large time behavior of Markov processes and their connection to the Feynman-Kac formula and the related large deviation behavior of the number of distinct sites visited by a random walk, and (iii) interacting particle systems, their scaling limits, and large deviations from their expected limits. For the most part the examples are worked out in detail, and in the process the subject of large deviations is developed. The book will give the reader a flavor of how large deviation theory can help in problems that are not posed directly in terms of large deviations. The reader is assumed to have some familiarity with probability, Markov processes, and interacting particle systems.
Hollander, Frank den
2008-01-01
This book is an introduction to the theory and applications of large deviations, a branch of probability theory that describes the probability of rare events in terms of variational problems. By focusing the theory, in Part A of the book, on random sequences, the author succeeds in conveying the main ideas behind large deviations without a need for technicalities, thus providing a concise and accessible entry to this challenging and captivating subject. The selection of modern applications, described in Part B of the book, offers a good sample of what large deviation theory is able to achieve
Standardized morbidity ratio for leptospirosis mapping in Malaysia
Awang, Aznida Che; Samat, Nor Azah
2017-05-01
Leptospirosis is a worldwide zoonotic disease that affects human health in many parts of the world including Malaysia. Leptospirosis is a disease caused by the infection of pathogenic Leptospira genus called Spirochaetes. Leptospirosis can be transmitted directly or indirectly from rats to human. The human infection is usually caused by human contact with urine or tissues of infected animal. This disease can be spread through mucus membrane such as mouth, nose and eyes, ingestion of contaminated food and water and also exposed injured skin to contaminated water or soil. There is still no vaccine currently available for the prevention or treatment of leptospirosis disease but this disease can be treated if it is diagnosed early. Therefore, the aim of this study is to estimate the relative risk for leptospirosis disease based initially on the most common statistic used in the study of disease mapping called Standardized Morbidity Ratio (SMR). We then apply SMR to leptospirosis data obtained in Malaysia. The results show that the states of Melaka have very high risk areas. The states of Kedah, Terengganu and Kelantan are identified as high risk areas. The states of Perak, Perlis, Sabah and Sarawak showed medium risk areas. This is followed by low risk by other states except Pahang, Johor and Labuan with very low risk areas. In conclusion, SMR method is the best method for mapping leptospirosis because by referring to the relative risk maps, the states that deserve closer look and disease prevention can be identified.
Vigren, E.; Eriksson, A. I.; Edberg, N. J. T.; Odelstad, E. [Swedish Institute of Space Physics, Uppsala (Sweden); Galand, M.; Schwartz, S. J., E-mail: erik.vigren@irfu.se [Department of Physics, Imperial College London, London, SW7 2AZ (United Kingdom)
2015-10-10
We compute partial photoionization frequencies of H{sub 2}O, CO{sub 2}, and CO, the major molecules in the coma of comet 67P/Churyumov–Gerasimenko, the target comet of the ongoing ESA Rosetta mission. Values are computed from Thermosphere Ionosphere Mesosphere Energy and Dynamics/Solar EUV Experiment solar EUV spectra for 2014 August 1, 2015 March 1, and for perihelion (2015 August, as based on prediction). From the varying total photoionization frequency of H{sub 2}O, as computed from 2014 August 1 to 2015 May 20, we derive a simple analytical expression for the electron-to-neutral number density ratio as a function of cometocentric and heliocentric distance. The underlying model assumes radial movement of the coma constituents and does not account for chemical loss or the presence of electric fields. We discuss various effects/processes that can cause deviations between values from the analytical expression and actual electron-to-neutral number density ratios. The analytical expression is thus not strictly meant as predicting the actual electron-to-neutral number density ratio, but is useful in comparisons with observations as an indicator of processes at play in the cometary coma.
Veenhoven, Ruut
2012-01-01
Inequality of happiness in nations can be measured using the standard deviation of responses to surveys questions. The standard-deviation is not quite independent of the mean, being zero when everybody is maximally happy or unhappy while the possible value of the standard deviation is highest when the mean is in the middle of the response scale. Delhey and Kohler see this intrinsic dependency as a problem and propose two ways to compute 'corrected' standard deviations. I advise against this medicine. One reason is that there is no real disease, since the presumed problem does not occur with commonly used numerical rating scales of 10 or more steps. The second reason is that one of Delhey and Kohler's medicines have side effects, their first correction affects the mean and their second correction is based on implausible assumptions. A third reason is that there are better ways to estimate the effect happiness-inequality net happiness-level. Partialling out mean happiness did not affect the non-correlation between inequality of income and inequality of happiness in an analysis of 116 nations. Copyright © 2011 Elsevier Inc. All rights reserved.
U.S. Geological Survey, Department of the Interior — This part of the data release contains a grid of standard deviations of bathymetric soundings within each 0.5 m x 0.5 m grid cell. The bathymetry was collected on...
Jansen, Rob T P; Laeven, Mark; Kardol, Wim
2002-06-01
The analytical processes in clinical laboratories should be considered to be non-stationary, non-ergodic and probably non-stochastic processes. Both the process mean and the process standard deviation vary. The variation can be different at different levels of concentration. This behavior is shown in five examples of different analytical systems: alkaline phosphatase on the Hitachi 911 analyzer (Roche), vitamin B12 on the Access analyzer (Beckman), prothrombin time and activated partial thromboplastin time on the STA Compact analyzer (Roche) and PO2 on the ABL 520 analyzer (Radiometer). A model is proposed to assess the status of a process. An exponentially weighted moving average and standard deviation was used to estimate process mean and standard deviation. Process means were estimated overall and for each control level. The process standard deviation was estimated in terms of within-run standard deviation. Limits were defined in accordance with state of the art- or biological variance-derived cut-offs. The examples given are real, not simulated, data. Individual control sample results were normalized to a target value and target standard deviation. The normalized values were used in the exponentially weighted algorithm. The weighting factor was based on a process time constant, which was estimated from the period between two calibration or maintenance procedures. The proposed system was compared with Westgard rules. The Westgard rules perform well, despite the underlying presumption of ergodicity. This is mainly caused by the introduction of the starting rule of 12s, which proves essential to prevent a large number of rule violations. The probability of reporting a test result with an analytical error that exceeds the total allowable error was calculated for the proposed system as well as for the Westgard rules. The proposed method performed better. The proposed algorithm was implemented in a computer program running on computers to which the analyzers were
Tomatsuri, K. (Taisei Corp., Tokyo (Japan))
1991-10-30
Concrete strength varies in accordance with material proportioning and age, and is usually mixed and designed at the determined age in order to manifest the specified strength. Concerning high strength concrete with design strength over 360kg/cm{sup 2}, however, there is no clear provision to estimate increse and deviation of the strength in the case where either age or cumulative temperature varies. In this study, the strength and the distribution of standard curing concrete and concrete after long piriod of time were measured and analyzed statistically in regard to 14 kinds of high strength concrete with the nominal strength between 360 to 465kg/cm{sup 2} of three construction projects. Considering that strength ratio of concrete at two different kinds of cumulative temperature showed the nominal distribution, a method to predict the strength distribution of concrete after a long period of time was presented. In this method, for instance, use of such parameters as standard deviation of strength on the 28th day of age and strength index could make it possible to predict the average strength and the standard deviation at different ages. 9 refs., 15 figs., 6 tabs.
Ren, Hongwu; Ding, Zhihua; Zhao, Yonghua; Miao, Jianjun; Nelson, J. Stuart; Chen, Zhongping
2002-10-01
We describe a phase-resolved functional optical coherence tomography system that can simultaneously yield in situ images of tissue structure, blood flow velocity, standard deviation, birefringence, and the Stokes vectors in human skin. Multifunctional images were obtained by processing of analytical interference fringe signals derived from two perpendicular polarization-detection channels. The blood flow velocity and standard deviation images were obtained by comparison of the phases from pairs of analytical signals in neighboring A-lines in the same polarization state. The analytical signals from two polarization-diversity detection channels were used to determine the four Stokes vectors for four reference polarization states. From the four Stokes vectors, the birefringence image, which is not sensitive to the orientation of the optical axis in the sample, was obtained. Multifunctional in situ images of a port wine stain birthmark in human skin are presented.
Standardization for oxygen isotope ratio measurement - still an unsolved problem.
Kornexl; Werner; Gehre
1999-07-01
Numerous organic and inorganic laboratory standards were gathered from nine European and North American laboratories and were analyzed for their delta(18)O values with a new on-line high temperature pyrolysis system that was calibrated using Vienna standard mean ocean water (VSMOW) and standard light Antartic precipitation (SLAP) internationally distributed reference water samples. Especially for organic materials, discrepancies between reported and measured values were high, ranging up to 2 per thousand. The reasons for these discrepancies are discussed and the need for an exact and reliable calibration of existing reference materials, as well as for the establishment of additional organic and inorganic reference materials is stressed. Copyright 1999 John Wiley & Sons, Ltd.
Belyakov A. V.
2016-01-01
Full Text Available The newest Large Hadron Collider experiments targeting the search for New Physics manifested the possibility of new heavy particles. Such particles are not predicted in the framework of Standard Model, however their existence is lawful in the framework of another model based on J. A.Wheeler’s geometrodynamcs.
Segmentation Using Symmetry Deviation
Hollensen, Christian; Højgaard, L.; Specht, L.
2011-01-01
and evaluate the method. The method uses deformable registration on computed tomography(CT) to find anatomical symmetry deviations of Head & Neck squamous cell carcinoma and combining it with positron emission tomography (PET) images. The method allows the use anatomical and symmetrical information of CT scans...... to improve automatic delineations. Materials: PET/CT scans from 30 patients were used for this study, 20 without cancer in hypopharyngeal volume and 10 with hypharyngeal carcinoma. An head and neck atlas was created from the 20 normal patients. The atlas was created using affine and non-rigid registration...... of the CT-scans into a single atlas. Afterwards the standard deviation of anatomical symmetry for the 20 normal patients was evaluated using non-rigid registration and registered onto the atlas to create an atlas for normal anatomical symmetry deviation. The same non-rigid registration was used on the 10...
12 CFR 3.11 - Standards for determination of appropriate individual minimum capital ratios.
2010-01-01
.../or affiliate(s); (d) The bank's liquidity, capital, risk asset and other ratios compared to the... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Standards for determination of appropriate individual minimum capital ratios. 3.11 Section 3.11 Banks and Banking COMPTROLLER OF THE...
Nielsen, Hanne-Marie; Groen, A F; Østergaard, Søren
2006-01-01
The objective of this paper was to present a model of a dairy cattle production system for the derivation of economic values and their standard deviations for both production and functional traits under Danish production circumstances. The stochastic model used is dynamic, and simulates production...... and health in a dairy herd. Because of indirect effects between traits, the phenotypic levels of (related) traits can change as a result of genetic changes. Economic values for milk production and body weight were 0.28 and -0.76 €/kg per cow-year respectively. For incidence of milk fever, mastitis, retained...... placenta and laminitis economic values were -402.1, -162.5, -79.0 and -210.2 €/incidence per cow-year. The economic values for involuntary culling rate, stillbirth and conception rate were -6.66, -1.63, and 1.98 €/% per cow-year, respectively and the economic value for days from calving to first heat...
Abdu. M. A. Atta
2011-12-01
Full Text Available In many statistical process control (SPC applications, the ease of use of control charts leads to ignoring the fact that the process population of the quality characteristic being measured may be highly skewed. However, in many situations, the normality assumption is usually violated. Among the recent heuristic charts for skewed distributions proposed in the literature are those based on the weighted standard deviation (WSD method. Thus, this paper compares the performances of certain WSD charts, such as WSD X , WSD Exponential weighted moving Average (WSDEWMA and WSD Cumulative Sum (WSD-CUSUM charts for skewed distributions. The skewed distributions being considered are weibull, gamma and lognormal. The false alarm and mean shift detection rates were computed so as to evaluate the performances of the WSD charts. The WSD X chart was found to have the lowest false alarm rate in cases of known and unknown parameters. Moreover, when parameters are known and unknown, the WSD-CUSUM provided the highest mean shift detection rates. The chart with the lowest false alarm and the highest mean shift detection rates for most level of skewness and sample size, n is assumed to be have a better performance.
78 FR 71817 - Liquidity Coverage Ratio: Liquidity Risk Measurement, Standards, and Monitoring
2013-11-29
.... Liquidity Characteristics of HQLA a. Risk Profile b. Market-based Characteristics c. Central Bank... supervision of Federal branches and agencies of foreign banks before considering applying a liquidity coverage... liquidity coverage ratio as an enhanced prudential standard for bank holding companies and savings and...
Requirement of standardized ileal digestible valine to lysine ratio for 8- to 14-kg pigs
Assadi Soumeh, Elham; van Milgen, Jaap; Sloth, Niels Morten;
2015-01-01
The objective was to define the Val requirement for weaned piglets in the context of reducing the dietary protein content. A dose–response experiment was conducted to estimate the standardized ileal digestible (SID) Val to Lys ratio required to support the optimum growth of post-weaned piglets. I...
Larsen, Michael Hareskov; Fristrup, Claus Wilki; Hansen, Tine Plato
2012-01-01
. Endoscopic sonoelastography (ESE) assesses the elasticity of lymph nodes and has been used to differentiate lymph nodes with promising results. The aim of this study was to evaluate the use of EUS, EUS - FNA, ESE, and ESE-strain ratio using histology as the gold standard. PATIENTS AND METHODS: Patients......, EUS - FNA and EUS - FNM were performed. The marked lymph node was isolated during surgery for histological examination. RESULTS: The marked lymph node was isolated for separate histological examination in 56 patients, of whom 22 (39 %) had malignant lymph nodes and 34 (61 %) had benign lymph nodes...... - FNM technique enabled the identification of a specific lymph node and thereby the use of histology as gold standard. ESE and ESE-strain ratio were no better than standard EUS in differentiating between malignant and benign lymph nodes in patients with resectable upper gastrointestinal cancer....
Construction of 3D Seabed Terrain Model based on the Standard Deviation Criterion%基于标准差准则的海底三维地形模型构建
韩富江; 潘胜玲; 王德刚; 来向华
2011-01-01
At present, existing triangulation must be done in the projection plane, so it causes the loss of attribution information in LOP (Local Optimization Procedure). In this paper, a new triangulation criterion based on standard deviation is used. The definition of standard deviation, calculation of standard deviation, and description of standard deviation criterion is investigated. Then the construction algorithm of 3D seabed terrain model based on standard deviation is presented according to the standard deviation criterion. The result of experiment shows that this method improves the rationality of triangulation, the details and precision of seabed terrain model are better than others, and it is better in dealing with special terrain than the algorithm based on empty circum-circle criterion.%针对现有三角剖分需要投影到平面,局部优化时属性丢失的问题,本文采用一种顾及水深属性的三角剖分准则——标准差准则进行三角剖分,并且讨论了标准差的含义、标准差的计算以及标准差准则的描述.根据标准差准则,实现了一种基于标准差差则的海底三维地形模型构建方法.实验结果表明该方法提高了三角剖分的合理性,模型重建的细节与精确程度更高,在处理特殊地形土优于基于空外接圆准则的TIN模型构建方法.
Chinn, Raymond; Lempp, Jason M; Huang, Susan S; Murthy, Rekha; Torriani, Francesca J; Daley, Jacqueline; Dekker, Elaine; Goss-Bottorff, Barbara; Kaler, Wendy; Meyer, Karen; Myers, Frank; Nichols, Amy; Kathleen Quan; Birnbaum, David
2016-11-01
The government publishes 3 different public report surgical site infection (SSI) metrics, all called standardized infection ratios (SIRs), that impact perceived hospital quality. We conducted a non-random cross-sectional observational pilot study of 20 California hospitals that voluntarily submitted colon surgery and SSI data. Discordant SIR values, leading to contradictory conclusions, occurred in 35% of these hospitals. Infect Control Hosp Epidemiol 2016;1-5.
Standardization of BOD₅/COD ratio as a biological stability index for MSW.
Cossu, Raffaello; Lai, Tiziana; Sandon, Annalisa
2012-08-01
The control of biodegradable substances is the key issue in evaluating the short and long-term emission potential and environmental impact of a landfill. Aerobic and anaerobic indices, such as respirometric index (RI) and biomethane potential production (GB21), can be used in the estimation of the stability of solid waste samples. Previous studies showed different degrees of relationship between BOD₅/COD ratio compared with RI4. Aim of this study is to standardize the parameter BOD₅/COD ratio and to test the methodology under different operating conditions (dynamic or static leaching and leaching duration, 6 and 24-h) keeping constant temperature and liquid/solid ratio (L/S=10 l/kg(TS)), with the introduction of a COD fractioning method. The COD fractioning is based on the differentiation between the soluble fraction (COD(sol)) and the colloidal fraction (COD(coll)) using a flocculation method. The BOD₅/COD and the BOD₅/COD(sol) indices are both consistent and significant and can be used as stability indices. The BOD₅/COD ratio does not seem to be influenced, for the same test duration, by the type of test, static or dynamic. In the same way the longer test duration (24-h) does not influence significantly the values of BOD₅/COD ratio. As a consequence a leaching test duration of 6-h is preferable to avoid the beginning of the hydrolysis and oxidation processes.
Impact of Changes in Accounting Standards in Debt Ratios of Firms: Evidence in Brazil
André Aroldo Freitas de Moura
2016-01-01
Full Text Available ABSTRACT This research investigates the impact of changes in debt ratios of Brazilian firms due to the IFRS adoption. We make a comparison between the forecast of the time-series of debt ratios accounted until 2007 for the span from 2008 to the first quarter of 2015 with those effectively accounted from 2008 to the first quarter of 2015 derived from the new accounting standard. The research utilizes SARIMAX model and Chow’s (1960 structural break forecast test, controlling for changes originating from the macroeconomic environment as well. We find evidence of significant changes in the debt ratio towards both higher and lower debt with predominance of greater ratios. This result is consistent with past literature in Europe, Australia and New Zealand. Nevertheless, we do not find evidence of a structural break in the Financial Dependency ratio. Moreover, there is no evidence of any distinct effects across different industries. The research provides new evidence confirming the informational effects of IFRS by utilizing a robust time-series model with macroeconomic controls in an innovative approach towards the accounting environment.
Dissociated Vertical Deviation
... Frequently Asked Questions Español Condiciones Chinese Conditions Dissociated Vertical Deviation En Español Read in Chinese What is Dissociated Vertical Deviation (DVD)? DVD is a condition in which ...
Analytical Expressions of the Efficiency of Standard and High Contact Ratio Involute Spur Gears
Miguel Pleguezuelos
2013-01-01
Full Text Available Simple, traditional methods for computation of the efficiency of spur gears are based on the hypotheses of constant friction coefficient and uniform load sharing along the path of contact. However, none of them is accurate. The friction coefficient is variable along the path of contact, though average values can be often considered for preliminary calculations. Nevertheless, the nonuniform load sharing produced by the changing rigidity of the pair of teeth has significant influence on the friction losses, due to the different relative sliding at any contact point. In previous works, the authors obtained a nonuniform model of load distribution based on the minimum elastic potential criterion, which was applied to compute the efficiency of standard gears. In this work, this model of load sharing is applied to study the efficiency of both standard and high contact ratio involute spur gears (with contact ratio between 1 and 2 and greater than 2, resp.. Approximate expressions for the friction power losses and for the efficiency are presented assuming the friction coefficient to be constant along the path of contact. A study of the influence of some transmission parameters (as the gear ratio, pressure angle, etc. on the efficiency is also presented.
Larsen, Michael Hareskov; Fristrup, Claus Wilki; Hansen, Tine Plato
2012-01-01
. Endoscopic sonoelastography (ESE) assesses the elasticity of lymph nodes and has been used to differentiate lymph nodes with promising results. The aim of this study was to evaluate the use of EUS, EUS - FNA, ESE, and ESE-strain ratio using histology as the gold standard. PATIENTS AND METHODS: Patients...... with upper gastrointestinal cancer who were referred for EUS examination were enrolled if surgical treatment was planned and the patient had a lymph node that was accessible for EUS - FNA and EUS-guided fine-needle marking (FNM). The lymph node was classified using EUS, ESE, and ESE-strain ratio. Finally......, EUS - FNA and EUS - FNM were performed. The marked lymph node was isolated during surgery for histological examination. RESULTS: The marked lymph node was isolated for separate histological examination in 56 patients, of whom 22 (39 %) had malignant lymph nodes and 34 (61 %) had benign lymph nodes...
An approach to adjust standardized mortality ratios for competing cause of death in cohort studies.
Möhner, Matthias
2016-05-01
The calculation of standardized mortality ratios (SMRs) is a standard tool for the estimation of health risks in occupational epidemiology. An increasing number of studies deal with the analysis of the mortality in employees suffering from an occupational disease like silicosis or coal-worker pneumoconiosis (CWP). Their focus lies not on the mortality risk due to the occupational disease itself, but on other diseases such as lung cancer or heart diseases. Using population-based reference rates in these studies can cause misleading results because mortality rates of the general population do not reflect the elevated mortality due to the occupational disease investigated. Hence, the purpose of the present paper is to develop an approach to adjust the risk estimates for other causes of death with respect to the effect of an occupational disease as a competing cause of death in occupational mortality cohort studies. To overcome the problems associated with SMRs, the paper makes use of proportional mortality ratios (PMR), which are a further approach for the estimation of health risks in occupational epidemiology. The cause-specific SMR can be rewritten as a product of PMR times the overall SMR. The PMR can be adjusted by ignoring the competing cause of death. Hence, an adjusted cause-specific SMR can be derived by multiplying this adjusted PMR with the overall SMR. This approach is applied to studies concerning lung cancer risk in coal miners suffering from CWP. The usual approach for calculating SMRs leads to an underestimation of the real lung cancer risk in subgroups of miners suffering from CWP. The same effect can be observed in workers exposed to respirable silica already suffering from silicosis. The presented approach results in more realistic risk estimation in mortality cohort studies of employees suffering from an occupational disease. It is easily calculable on the basis of usually published values of observed cases and the corresponding cause-specific SMR.
Bladder cancer mapping in Libya based on standardized morbidity ratio and log-normal model
Alhdiri, Maryam Ahmed; Samat, Nor Azah; Mohamed, Zulkifley
2017-05-01
Disease mapping contains a set of statistical techniques that detail maps of rates based on estimated mortality, morbidity, and prevalence. A traditional approach to measure the relative risk of the disease is called Standardized Morbidity Ratio (SMR). It is the ratio of an observed and expected number of accounts in an area, which has the greatest uncertainty if the disease is rare or if geographical area is small. Therefore, Bayesian models or statistical smoothing based on Log-normal model are introduced which might solve SMR problem. This study estimates the relative risk for bladder cancer incidence in Libya from 2006 to 2007 based on the SMR and log-normal model, which were fitted to data using WinBUGS software. This study starts with a brief review of these models, starting with the SMR method and followed by the log-normal model, which is then applied to bladder cancer incidence in Libya. All results are compared using maps and tables. The study concludes that the log-normal model gives better relative risk estimates compared to the classical method. The log-normal model has can overcome the SMR problem when there is no observed bladder cancer in an area.
The Strip Scratch Analysis Method Based on Sample Standard Deviation%基于样本标准差理论的带钢板面划伤分析方法
陈代兵; 纪马力; 杨子秀; 连旭东
2014-01-01
For the discrimination of strip scratch which is caused by roll touch in continuous line , and the estimation of speed deviation wheather can make a influence on strip surface , this paper provides a new analysis method .It introduces the process of strip scratch that appears in the roll touch .Especially ,it shows the factors which will result in speed deviation .Al-so,it proposes the use of sample standard deviation method in the analysis , and the value which can lead to scratch .Finally, it provides the solution of speed deviation and share the experience in analysis with readers .When this method is widely used in the process of strip scratch analysis ,we can exactly discriminate the factors of scratch ,and resolve the speed deviation quickly .%为区分连续生产线上带钢板面划伤缺陷的来源，判断辊子速度偏差对板面质量的影响，进而解决这种产品缺陷，本文提出了一种新分析方法。通过介绍带钢板面划伤缺陷产生的机理，着重指出了造成辊子速度偏差的因素，将样本标准差理论运用到偏差的分析中，明确了造成划伤的速度偏差值，最后介绍了解决速度偏差的排查方法和经验。该分析方法在生产中得到推广运用，实现了准确识别缺陷来源、快速解决速度偏差的目的。
Requirement of standardized ileal digestible valine to lysine ratio for 8- to 14-kg pigs.
Soumeh, E A; van Milgen, J; Sloth, N M; Corrent, E; Poulsen, H D; Nørgaard, J V
2015-08-01
The objective was to define the Val requirement for weaned piglets in the context of reducing the dietary protein content. A dose-response experiment was conducted to estimate the standardized ileal digestible (SID) Val to Lys ratio required to support the optimum growth of post-weaned piglets. In this study, 96 pigs weighing 8 kg were allotted to one of six dietary treatments (16 pigs for each dietary treatment) and were housed individually. Diets were formulated to provide 0.58, 0.62, 0.66, 0.70, 0.74 and 0.78 SID Val : Lys by adding graded levels of crystalline l-Val to the 0.58 SID Val : Lys diet. Lysine was sub-limiting and supplied 90% of the recommendation (10.95 g SID Lys/kg equal to 11.8 g/kg total Lys). Average daily feed intake (ADFI), average daily gain (ADG) and gain to feed ratio (G : F) were determined during a 14-day period of ad libitum feeding. Blood and urine samples were taken at the end of each week (day 7 and 14 of the experiment) 3 h after feeding the experimental diets. The maximum ADFI and ADG were obtained in pigs fed the 0.78 SID Val : Lys diet; it was not different from the results of pigs fed 0.70 SID Val : Lys diet. The highest G : F was obtained in pigs fed 0.70 SID Val : Lys. The plasma concentration of Val increased linearly (P<0.001) as the dietary SID Val : Lys increased. The increasing dietary Val : Lys also resulted in a linear increase in Cys (P<0.001) and a quadratic increase in Arg (P=0.003), Lys (P=0.05) and Phe (P=0.009). The plasma Gly showed a quadratic decrease (P=0.05) as the dietary Val : Lys increased. Neither plasma nor urinary urea to creatinine ratio was affected by treatment. The minimum SID Val : Lys required to maximize ADFI, ADG and G : F was estimated at 0.67 SID Val : Lys by a broken-line model, and at 0.71 SID Val : Lys by a curvilinear plateau model. The Val deficiency caused a reduction in ADFI, and Val supplementation above the requirement did not impair animal performance. In conclusion, 0.70 SID Val
Ohsawa, Masaki; Kato, Karen; Itai, Kazuyoshi; Tanno, Kozo; Fujishima, Yosuke; Konda, Ryuichiro; Okayama, Akira; Abe, Koichi; Suzuki, Kazuyuki; Nakamura, Motoyuki; Onoda, Toshiyuki; Kawamura, Kazuko; Sakata, Kiyomi; Akiba, Takashi; Fujioka, Tomoaki
2010-01-01
Background Many studies have estimated the prevalence of anti-hepatitis C virus (HCV) antibody among hemodialysis (HD) patients; however, the prevalence of HCV core antigen—which indicates the presence of chronic HCV infection—is not known. Methods Standardized prevalence ratios (SPRs) for anti-HCV antibody and HCV core antigen among HD patients (n = 1214) were calculated on the basis of data from the general population (n = 22 472) living in the same area. Results The prevalences of anti-HCV antibody and HCV core antigen were 12.5% and 7.8%, respectively, in male hemodialysis patients, and 8.5% and 4.1% in female hemodialysis patients. The SPRs (95% confidence interval) for anti-HCV antibody and HCV core antigen were 8.39 (6.72–10.1) and 12.9 (9.66–16.1), respectively, in males, and 5.42 (3.67–7.17) and 8.77 (4.72–12.8) in females. Conclusions The prevalences of chronic HCV infection among male and female HD patients were 13-fold and 9-fold, respectively, those of the population-based controls. Further studies should therefore be conducted to determine the extent of chronic HCV infection among HD patients in other populations and to determine whether chronic HCV infection contributes to increased mortality in HD patients. PMID:19881229
Saglio, Giuseppe; le Coutre, Philipp; Cortes, Jorge; Mayer, Jiří; Rowlings, Philip; Mahon, François-Xavier; Kroog, Glenn; Gooden, Kyna; Subar, Milayna; Shah, Neil P
2017-08-01
With high survival rates for chronic myeloid leukemia (CML) patients treated with BCR-ABL1 tyrosine kinase inhibitors (TKIs), emerging consequences, such as arterial ischemic events, require consideration when evaluating treatment options. Cardiovascular ischemic event incidence in clinical trials was evaluated in 2712 dasatinib-treated patients with Philadelphia chromosome-positive (Ph+) leukemias from 11 first- and second-line trials (pooled), newly diagnosed CML patients treated with dasatinib or imatinib (DASISION), and prostate cancer patients treated with dasatinib or placebo plus docetaxel/prednisone (READY). Overall, 2-4% of dasatinib-treated patients had cardiovascular ischemic events. Most dasatinib-treated patients with an event had a history of and/or risk factor for atherosclerosis (pooled 77 with history/risk and event/96 with events; DASISION 8/10; READY 15/18). Most cardiovascular ischemic events occurred within 1 year of initiating dasatinib (pooled 69/96; DASISION 7/10; READY 16/18). Comparison of observed and expected event rates through standardized incidence ratios indicates that dasatinib does not increase risk for cardiovascular ischemic events compared with external reference populations.
Calculation on Batch Standard Deviation of the Blank and Methods Detection Limit%空白批内标准偏差和方法检出限的计算
祝旭初
2014-01-01
In environmental analytical chemistry,especially trace analysis,the methods detection limit for the reported results of the monitoring is extremely important. Determination of the detection limit often involves with calculating the standard deviation of the blank. Based on the analysis of a typical case,it was pointed out that part of the revised environmental standard method of using the new system between batches blank to calculate the standard deviation of the detection limit was unreasonable. Before calculating the detection limit it is necessary to determine whether there are significant differences between batches.%环境分析化学中，尤其痕量分析时，方法检出限对于监测结果的报出很重要。检出限的确定常会涉及空白标准偏差的计算。通过对一典型案例剖析，指出一部分新制修订环境标准方法采用空白批间标准偏差计算检出限是不合理的。在求算检出限时应先判断批间是否存在显著性差异。
Large Deviations and Metastability
Olivieri, Enzo; Eulália Vares, Maria
2005-02-01
This self-contained account of the main results in large deviation theory includes recent developments and emphasizes the Freidlin-Wentzell results on small random perturbations. Metastability is described on physical grounds, followed by the development of more exacting approaches to its description. The first part of the book then develops such pertinent tools as the theory of large deviations which is used to provide a physically relevant dynamical description of metastability. Written for graduate students, this book affords an excellent route into contemporary research as well.
Increased standardized incidence ratio of breast cancer in female electronics workers
Lin Yi-Ping
2007-06-01
Full Text Available Abstract Background In 1994, a hazardous waste site, polluted by the dumping of solvents from a former electronics factory, was discovered in Taoyuan, Taiwan. This subsequently emerged as a serious case of contamination through chlorinated hydrocarbons with suspected occupational cancer. The objective of this study was to determine if there was any increased risk of breast cancer among female workers in a 23-year follow-up period. Methods A total of 63,982 female workers were retrospectively recruited from the database of the Bureau of Labor Insurance (BLI covering the period 1973–1997; the data were then linked with data, up to 2001, from the National Cancer Registry at the Taiwanese Department of Health, from which standardized incidence ratios (SIRs for different types of cancer were calculated as compared to the general population. Results There were a total of 286 cases of breast cancer, and after adjustment for calendar year and age, the SIR was close to 1. When stratified by the year 1974 (the year in which the regulations on solvent use were promulgated, the SIR of the cohort of workers who were first employed prior to 1974 increased to 1.38 (95% confidence interval, 1.11–1.70. No such trend was discernible for workers employed after 1974. When 10 years of employment was considered, there was a further increase in the SIR for breast cancer, to 1.62. Those workers with breast cancer who were first employed prior to 1974 were employed at a younger age and for a longer period. Previous qualitative studies of interviews with the workers, corroborated by inspection records, showed a short-term high exposure to chlorinated alkanes and alkenes, particularly trichloroethylene before 1974. There were no similar findings on other types of cancer. Conclusion Female workers with exposure to trichloroethylene and/or mixture of solvents, first employed prior to 1974, may have an excess risk of breast cancer.
POSSIBILISTIC SHARPE RATIO BASED NOVICE PORTFOLIO SELECTION MODELS
Rupak Bhattacharyya
2013-01-01
This paper uses the concept of possibilistic risk aversion to propose a new approach for portfolio selection in fuzzy environment. Using possibility theory, the possibilistic mean, variance, standard deviation and risk premium of a fuzzy number are established. Possibilistic Sharpe ratio is defined as the ratio of possibilistic risk premium and possibilistic standard deviation of a portfolio. The Sharpe ratio is a measure of the performance of the portfolio compared to the risk...
Fan Aihua
2004-01-01
The vertices of an infinite locally finite tree T are labelled by a collection of i.i.d. real random variables {Xσ}σ∈T which defines a tree indexed walk Sσ = ∑θ＜r≤σXr. We introduce and study the oscillations of the walk:Exact Hausdorff dimension of the set of such ξ 's is calculated. An application is given to study the local variation of Brownian motion. A general limsup deviation problem on trees is also studied.
Marianna Rakszegi
2016-06-01
Full Text Available An assessment was previously made of the effects of organic and low-input field management systems on the physical, grain compositional and processing quality of wheat and on the performance of varieties developed using different breeding methods (“Comparison of quality parameters of wheat varieties with different breeding origin under organic and low-input conventional conditions” [1]. Here, accompanying data are provided on the performance and stability analysis of the genotypes using the coefficient of variation and the ‘ranking’ and ‘which-won-where’ plots of GGE biplot analysis for the most important quality traits. Broad-sense heritability was also evaluated and is given for the most important physical and quality properties of the seed in organic and low-input management systems, while mean values and standard deviation of the studied properties are presented separately for organic and low-input fields.
Rakszegi, Marianna; Löschenberger, Franziska; Hiltbrunner, Jürg; Vida, Gyula; Mikó, Péter
2016-06-01
An assessment was previously made of the effects of organic and low-input field management systems on the physical, grain compositional and processing quality of wheat and on the performance of varieties developed using different breeding methods ("Comparison of quality parameters of wheat varieties with different breeding origin under organic and low-input conventional conditions" [1]). Here, accompanying data are provided on the performance and stability analysis of the genotypes using the coefficient of variation and the 'ranking' and 'which-won-where' plots of GGE biplot analysis for the most important quality traits. Broad-sense heritability was also evaluated and is given for the most important physical and quality properties of the seed in organic and low-input management systems, while mean values and standard deviation of the studied properties are presented separately for organic and low-input fields.
Optimum standardized ileal digestible tryptophan to lysine ratio for pigs weighing 7–14 kg
Nørgaard, Jan Værum; Pedersen, Trine Friis; Assadi Soumeh, Elham
2015-01-01
/treatment. The diets contained similar crude protein (154 g/kg), NE (10.5 MJ/kg), and SID Lys (10.9 g/kg). Average daily feed intake (ADFI), average daily gain (ADG), and gain to feed ratio (G:F) were determined for a 21-d period. Blood and urine samples were collected on d 8 and 15. Urea concentration in plasma...
Large deviations and portfolio optimization
Sornette, Didier
Risk control and optimal diversification constitute a major focus in the finance and insurance industries as well as, more or less consciously, in our everyday life. We present a discussion of the characterization of risks and of the optimization of portfolios that starts from a simple illustrative model and ends by a general functional integral formulation. A major item is that risk, usually thought of as one-dimensional in the conventional mean-variance approach, has to be addressed by the full distribution of losses. Furthermore, the time-horizon of the investment is shown to play a major role. We show the importance of accounting for large fluctuations and use the theory of Cramér for large deviations in this context. We first treat a simple model with a single risky asset that exemplifies the distinction between the average return and the typical return and the role of large deviations in multiplicative processes, and the different optimal strategies for the investors depending on their size. We then analyze the case of assets whose price variations are distributed according to exponential laws, a situation that is found to describe daily price variations reasonably well. Several portfolio optimization strategies are presented that aim at controlling large risks. We end by extending the standard mean-variance portfolio optimization theory, first within the quasi-Gaussian approximation and then using a general formulation for non-Gaussian correlated assets in terms of the formalism of functional integrals developed in the field theory of critical phenomena.
Large deviations from freeness
Kargin, Vladislav
2010-01-01
Let H=A+UBU* where A and B are two N-by-N Hermitian matrices and U is a Haar-distributed random unitary matrix, and let \\mu_H, \\mu_A, and \\mu_B be empirical measures of eigenvalues of matrices H, A, and B, respectively. Then, it is known (see, for example, Pastur-Vasilchuk, CMP, 2000, v.214, pp.249-286) that for large N, measure \\mu_H is close to the free convolution of measures \\mu_A and \\mu_B, where the free convolution is a non-linear operation on probability measures. The large deviations of the cumulative distribution function of \\mu_H from its expectation have been studied by Chatterjee in JFA, 2007, v. 245, pp.379-389. In this paper we improve Chatterjee's estimate and show that P {\\sup_x |F_H (x) -F_+ (x)| > \\delta} < exp [-f(\\delta) N^2], where F_H (x) and F_+ (x) denote the cumulative distribution functions of \\mu_H and the free convolution of \\mu_A and \\mu_B, respectively, and where f(\\delta) is a specific function.
Are there standardized cutoff values for neutrophil-lymphocyte ratios in bacteremia or sepsis?
Gürol, Gölnül; Çiftci, İhsan Hakki; Terizi, Huseyin Agah; Atasoy, Ali Rıza; Ozbek, Ahmet; Köroğlu, Mehmet
2015-04-01
Bacteremia and sepsis are common causes of morbidity and mortality worldwide, with incorrect or delayed diagnoses being associated with increased mortality. New tests or markers that allow a more rapid and less costly detection of bacteremia and sepsis have been investigated. The aim of this study was to clarify the cutoff value of the neutrophillymphocyte ratio (NLR) according to procalcitonin (PCT) level in the decision-making processes for bacteremia and sepsis. In addition, other white blood cell subgroup parameters, which are assessed in all hospitals, for bacteremia and sepsis were explored. This retrospective study included 1,468 patients with suspected bacteremia and sepsis. Patients were grouped according to the following PCT criteria: levels sepsis group), and >10 ng/ml (sepsis shock group). One important finding of this study, which will serve as a baseline to measure future progress, is the presence of many gaps in the information on pathogens that constitute a major health risk. In addition, clinical decisions are generally not coordinated, compromising the ability to assess and monitor a situation. This report represents the first study to determine the limits of the use of NLR in the diagnosis of infection or sepsis using a cutoff value of <5 when sufficient exclusion criteria are used.
B. T. Poh
2013-01-01
Full Text Available Viscosity, tack and, peel and shear strengths of ethylene-propylene-diene rubber (EPDM/standard Malaysian rubber (SMR L blend adhesive were studied using various blend ratios of the two rubbers, ranging from 0 to 100% EPDM. Coumarone-indene resin, toluene, and poly(ethylene terephthalate (PET were used as the tackifier, solvent, and coating substrate, respectively. The tackifier content was fixed at 40 parts per hundred parts of rubber (phr. A SHEEN hand coater was used to coat the adhesive on PET film at four coating thicknesses, that is, 30, 60, 90, and 120 µm. The viscosity and adhesion properties were determined by a Brookfield viscometer and a Lloyd Adhesion Tester, respectively. Results show that the viscosity, loop tacks and peel strength of blend adhesives decrease gradually with increasing % EPDM. This observation is attributed to dilution effect and lowering in wettability and compatibility. Shear strength, however, passes through a maximum at 20–40% EPDM blend ratio, an observation which is ascribed to culmination of cohesive strength at the optimum EPDM blend ratio. Increasing coating thickness increases the adhesion properties in all blend ratios in this study.
Large deviations and idempotent probability
Puhalskii, Anatolii
2001-01-01
In the view of many probabilists, author Anatolii Puhalskii''s research results stand among the most significant achievements in the modern theory of large deviations. In fact, his work marked a turning point in the depth of our understanding of the connections between the large deviation principle (LDP) and well-known methods for establishing weak convergence results.Large Deviations and Idempotent Probability expounds upon the recent methodology of building large deviation theory along the lines of weak convergence theory. The author develops an idempotent (or maxitive) probability theory, introduces idempotent analogues of martingales (maxingales), Wiener and Poisson processes, and Ito differential equations, and studies their properties. The large deviation principle for stochastic processes is formulated as a certain type of convergence of stochastic processes to idempotent processes. The author calls this large deviation convergence.The approach to establishing large deviation convergence uses novel com...
Explorations in Statistics: Standard Deviations and Standard Errors
Curran-Everett, Douglas
2008-01-01
Learning about statistics is a lot like learning about science: the learning is more meaningful if you can actively explore. This series in "Advances in Physiology Education" provides an opportunity to do just that: we will investigate basic concepts in statistics using the free software package R. Because this series uses R solely as a vehicle…
X. Q. Bao; E. Cattan
2011-01-01
This work presents our understanding of insect wings, and the design and micromachining of artificial wings with golden ratio-based and tapered veins. The geometric anisotropy of Leading Edge Veins (LEVs) selected by Diptera has a function able to evade impact. As a Diptera example, the elliptic hollow LEVs of cranefly wings are mechanically and aerodynamically significant. In this paper, an artificial wing was designed to be a fractal structure by mimicking cranefly wings and incorporating cross-veins and discal cell. Standard technologies of Microelectromechanical Systems (MEMS) were employed to materialize the design using the selected material. One SU-8 wing sample, light and stiff enough to be comparable to fresh cranefly wings,was presented. The as-prepared SU-8 wings are faithful to real wings not only in weight and vein pattern, but also in flexural stiffness and mass distribution. Thus our method renders possible mimicking with good fidelity of natural wings with complex geometry and morphology.
Sampalis, J S; Lavoie, A; Williams, J I; Mulder, D S; Kalina, M
1992-08-01
Flora's Z statistic and standardized mortality ratios (SMRs) as indicators of excess mortality were calculated for a sample of 355 patients with major trauma. A statistically significant overall excess mortality was observed in this sample (Z = 6.77, SMR = 1.81, p less than 0.05). Advanced life support provided by physicians at the scene (MD-ALS) was not associated with reduced excess mortality. A significant trend toward lower excess mortality was associated with a higher level of trauma care at the receiving hospital (p less than 0.05). Total prehospital time over 60 minutes was associated with a significant increase in excess mortality (p less than 0.001). These results support regionalization of trauma care and failed to show any benefit associated with MD-ALS.
Masina, Isabella; Notari, Alessio
2012-05-11
For a narrow band of values of the top quark and Higgs boson masses, the standard model Higgs potential develops a false minimum at energies of about 10(16) GeV, where primordial inflation could have started in a cold metastable state. A graceful exit to a radiation-dominated era is provided, e.g., by scalar-tensor gravity models. We pointed out that if inflation happened in this false minimum, the Higgs boson mass has to be in the range 126.0±3.5 GeV, where ATLAS and CMS subsequently reported excesses of events. Here we show that for these values of the Higgs boson mass, the inflationary gravitational wave background has be discovered with a tensor-to-scalar ratio at hand of future experiments. We suggest that combining cosmological observations with measurements of the top quark and Higgs boson masses represent a further test of the hypothesis that the standard model false minimum was the source of inflation in the universe.
Estimation of the standardized ileal digestible valine-to-lysine ratio in 13- to 32-kilogram pigs.
Gaines, A M; Kendall, D C; Allee, G L; Usry, J L; Kerr, B J
2011-03-01
Three experiments were conducted to determine the optimum standardized ileal digestible Val-to-Lys (SID Val:Lys) ratio for 13- to 32-kg pigs. In Exp. 1, 162 pigs weaned at 17 d of age (8 pens/treatment) were used, and a Val-deficient basal diet containing 0.60% l-Lys·HCl, 1.21% SID Lys, and 0.68% SID Val was developed (0.56 SID Val:Lys). Performance of pigs fed the basal diet was inferior to a corn-soybean meal control containing only 0.06% l-Lys·HCl, but was fully restored with the addition of 0.146% l-Val to the basal diet (68% SID Val:Lys). In Exp. 2, 54 individually housed barrows (21.4 kg) were utilized in a 14-d growth assay. Pigs were offered a similar basal diet (1.10% SID Lys), ensuring Lys was marginally limiting with no supplemental l-Val (55% SID Val:Lys). The basal diet was fortified with 4 graded levels of l-Val (0.055% increments) up to a ratio of 75% SID Val:Lys. In Exp. 3, 147 barrows (13.5 kg) were fed identical diets, only with 1 additional level at a SID Val:Lys of 80% and fed for 21 d. In Exp. 2 and 3, a high protein, control diet was formulated to contain 1.10% SID Lys and 0.20% l-Lys·HCl. In Exp. 2, linear effects on ADG (713, 750, 800, 796, and 785 g/d; P = 0.05) and G:F (P = 0.07) were observed with increasing SID Val:Lys, characterized by improvements to a ratio of 65% and a plateau thereafter. In Exp. 3, quadratic improvements in ADG (600, 629, 652, 641, 630, and 642 g/d; P = 0.08) and G:F (P = 0.07) were observed with increasing SID Val:Lys, as performance increased to a ratio of 65% but no further improvement to a ratio of 80%. Pigs fed the control diet did not differ from those fed a ratio of 65% SID Val:Lys in Exp. 2, but did have improved G:F in Exp. 3 (P = 0.03). To provide a more accurate estimate of the optimum SID Val:Lys, data from Exp. 2 and 3 were combined. With single-slope broken-line methodology, the minimum ratio estimate was 64 and 65% SID Val:Lys for ADG and G:F, respectively. With combined requirement estimates, the
Semantic Deviation in Oliver Twist
康艺凡
2016-01-01
Dickens, with his adeptness with language, applies semantic deviation skillfully in his realistic novel Oliver Twist. However, most studies and comments home and abroad on it mainly focus on such aspects as humanity, society, and characters. Therefore, this thesis will take a stylistic approach to Oliver Twist from the perspective of semantic deviation, which is achieved by the use of irony, hyperbole, and pun and analyze how the application of the technique makes the novel attractive.
Paroxysmal upgaze deviation: case report
Echeverría-Palacio CM; Benavidez-Fierro MA
2012-01-01
The paroxysmal upgaze deviation is a syndrome that described in infants for first time in 1988; there are just about 50 case reports worldwide ever since. Its etiology is unclear and though it prognosis is variable; most case reports indicate that during growth the episodes tend to decrease in frequency and duration until they disappear. It describes a 16-months old male child who since 11-months old presented many episodes of variable conjugate upward deviation of the eyes, compensatory neck...
Angle-deviation optical profilometer
Chen-Tai Tan; Yuan-Sheng Chan; Zhen-Chin Lin; Ming-Hung Chiu
2011-01-01
@@ We propose a new optical profilometer for three-dimensional (3D) surface profile measurement in real time.The deviation angle is based on geometrical optics and is proportional to the apex angle of a test plate.Measuring the reflectivity of a parallelogram prism allows detection of the deviation angle when the beam is incident at the nearby critical angle. The reflectivity is inversely proportional to the deviation angle and proportional to the apex angle and surface height. We use a charge-coupled device (CCD) camera at the image plane to capture the reflectivity profile and obtain the 3D surface profile directly.%We propose a new optical profilometer for three-dimensional (3D) surface profile measurement in real time.The deviation angle is based on geometrical optics and is proportional to the apex angle of a test plate.Measuring the refiectivity of a parallelogram prism allows detection of the deviation angle when the beam is incident at the nearby critical angle. The refiectivity is inversely proportional to the deviation angle and proportional to the apex angle and surface height. We use a charge-coupled device (CCD) camera at the image plane to capture the refiectivity profile and obtain the 3D surface profile directly.
Timkova, Jana; Kotik, Lukas; Tomasek, Ladislav
2017-08-16
This paper assesses the coverage probability of commonly used confidence intervals for the standardized mortality ratio (SMR) when death certificates are missing. It also proposes alternative confidence interval approaches with coverage probabilities close to .95. In epidemiology, the SMR is an important measure of risk of disease mortality (or incidence) to compare a specific group to a reference population. The appropriate confidence interval for the SMR is crucial, especially when the SMR is close to 1.0 and the statistical significance of the risk needs to be determined. There are several ways to calculate confidence intervals, depending on a study characteristics (ie, studies with small number of deaths, studies with small counts, aggregate SMRs based on several countries or time periods, and studies with missing death certificates). This paper summarizes the most commonly used confidence intervals and newly applies several existing approaches not previously used for SMR confidence intervals. The coverage probability and length of the different confidence intervals are assessed using a simulation study and different scenarios. The performance of the confidence intervals for the lung cancer SMR and all other cancer SMR is also assessed using the dataset of French and Czech uranium miners. Finally, the most appropriate confidence intervals to use under different study scenarios are recommended. Copyright © 2017 John Wiley & Sons, Ltd.
Confusing Sterile Neutrinos with Deviation from Tribimaximal Mixing at Neutrino Telescopes
Awasthi, Ram Lal
2007-01-01
We expound the impact of extra sterile species on the ultra high energy neutrino fluxes in neutrino telescopes. We use three types of well-known flux ratios and compare the values of these flux ratios in presence of sterile neutrinos, with those predicted by deviation from the tribimaximal mixing scheme. We show that in neutrino telescopes, its easy to confuse between the signature of sterile neutrinos with that of the deviation from tribimaximal mixing. We also show that if the measured flux ratios acquire a value well outside the range predicted by the standard scenario with three active neutrinos only, it might be possible to tell the presence of extra sterile neutrinos by observing ultra high energy neutrinos in the upcoming neutrino telescopes.
无
2002-01-01
A relationship is established, using the least-squares method, between the standard enthalpy of formation and the standard enthalpy of formation divided by the exothermic denitration decomposition peak absolute temperature corresponding to β→0.
Large deviations in Taylor dispersion
Kahlen, Marcel; Engel, Andreas; Van den Broeck, Christian
2017-01-01
We establish a link between the phenomenon of Taylor dispersion and the theory of empirical distributions. Using this connection, we derive, upon applying the theory of large deviations, an alternative and much more precise description of the long-time regime for Taylor dispersion.
Cameron Lorraine L
2007-02-01
Full Text Available Abstract Background Exposure to arsenic concentrations in drinking water in excess of 300 μg/L is associated with diseases of the circulatory and respiratory system, several types of cancer, and diabetes; however, little is known about the health consequences of exposure to low-to-moderate levels of arsenic (10–100 μg/L. Methods A standardized mortality ratio (SMR analysis was conducted in a contiguous six county study area of southeastern Michigan to investigate the relationship between moderate arsenic levels and twenty-three selected disease outcomes. Disease outcomes included several types of cancer, diseases of the circulatory and respiratory system, diabetes mellitus, and kidney and liver diseases. Arsenic data were compiled from 9251 well water samples tested by the Michigan Department of Environmental Quality from 1983 through 2002. Michigan Resident Death Files data were amassed for 1979 through 1997 and sex-specific SMR analyses were conducted with indirect adjustment for age and race; 99% confidence intervals (CI were reported. Results The six county study area had a population-weighted mean arsenic concentration of 11.00 μg/L and a population-weighted median of 7.58 μg/L. SMR analyses were conducted for the entire six county study area, for only Genesee County (the most populous and urban county, and for the five counties besides Genesee. Concordance of results across analyses is used to interpret the findings. Elevated mortality rates were observed for both males (M and females (F for all diseases of the circulatory system (M SMR, 1.11; CI, 1.09–1.13; F SMR, 1.15; CI, 1.13,-1.17, cerebrovascular diseases (M SMR, 1.19; CI, 1.14–1.25; F SMR, 1.19; CI, 1.15–1.23, diabetes mellitus (M SMR, 1.28; CI, 1.18–1.37; F SMR, 1.27; CI, 1.19–1.35, and kidney diseases (M SMR, 1.28; CI, 1.15–1.42; F SMR, 1.38; CI, 1.25–1.52. Conclusion This is some of the first evidence to suggest that exposure to low-to-moderate levels of
Che Awang, Aznida; Azah Samat, Nor
2017-09-01
Leptospirosis is a disease caused by the infection of pathogenic species from the genus of Leptospira. Human can be infected by the leptospirosis from direct or indirect exposure to the urine of infected animals. The excretion of urine from the animal host that carries pathogenic Leptospira causes the soil or water to be contaminated. Therefore, people can become infected when they are exposed to contaminated soil and water by cut on the skin as well as open wound. It also can enter the human body by mucous membrane such nose, eyes and mouth, for example by splashing contaminated water or urine into the eyes or swallowing contaminated water or food. Currently, there is no vaccine available for the prevention or treatment of leptospirosis disease but this disease can be treated if it is diagnosed early to avoid any complication. The disease risk mapping is important in a way to control and prevention of disease. Using a good choice of statistical model will produce a good disease risk map. Therefore, the aim of this study is to estimate the relative risk for leptospirosis disease based initially on the most common statistic used in disease mapping called Standardized Morbidity Ratio (SMR) and Poisson-gamma model. This paper begins by providing a review of the SMR method and Poisson-gamma model, which we then applied to leptospirosis data of Kelantan, Malaysia. Both results are displayed and compared using graph, tables and maps. The result shows that the second method Poisson-gamma model produces better relative risk estimates compared to the SMR method. This is because the Poisson-gamma model can overcome the drawback of SMR where the relative risk will become zero when there is no observed leptospirosis case in certain regions. However, the Poisson-gamma model also faced problems where the covariate adjustment for this model is difficult and no possibility for allowing spatial correlation between risks in neighbouring areas. The problems of this model have
Paroxysmal upgaze deviation: case report
Echeverría-Palacio CM
2012-05-01
Full Text Available The paroxysmal upgaze deviation is a syndrome that described in infants for first time in 1988; there are just about 50 case reports worldwide ever since. Its etiology is unclear and though it prognosis is variable; most case reports indicate that during growth the episodes tend to decrease in frequency and duration until they disappear. It describes a 16-months old male child who since 11-months old presented many episodes of variable conjugate upward deviation of the eyes, compensatory neck flexion and down-beat saccades in attempted downgaze. These events are predominantly diurnal, and are exacerbated by stressful situations such as fasting or insomnia, however and improve with sleep. They have normal neurologic and ophthalmologic examination, and neuroimaging and EEG findings are not relevant.
Perception of aircraft Deviation Cues
Martin, Lynne; Azuma, Ronald; Fox, Jason; Verma, Savita; Lozito, Sandra
2005-01-01
To begin to address the need for new displays, required by a future airspace concept to support new roles that will be assigned to flight crews, a study of potentially informative display cues was undertaken. Two cues were tested on a simple plan display - aircraft trajectory and flight corridor. Of particular interest was the speed and accuracy with which participants could detect an aircraft deviating outside its flight corridor. Presence of the trajectory cue significantly reduced participant reaction time to a deviation while the flight corridor cue did not. Although non-significant, the flight corridor cue seemed to have a relationship with the accuracy of participants judgments rather than their speed. As this is the second of a series of studies, these issues will be addressed further in future studies.
48 CFR 2001.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Individual deviations. 2001... Individual deviations. In individual cases, deviations from either the FAR or the NRCAR will be authorized... deviations clearly in the best interest of the Government. Individual deviations must be authorized...
48 CFR 801.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Individual deviations. 801... Individual deviations. (a) Authority to authorize individual deviations from the FAR and VAAR is delegated to... nature of the deviation. (d) The DSPE may authorize individual deviations from the FAR and VAAR when...
48 CFR 1301.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Individual deviations... DEPARTMENT OF COMMERCE ACQUISITION REGULATIONS SYSTEM Deviations From the FAR 1301.403 Individual deviations. The designee authorized to approve individual deviations from the FAR is set forth in CAM 1301.70....
48 CFR 401.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Individual deviations. 401... AGRICULTURE ACQUISITION REGULATION SYSTEM Deviations From the FAR and AGAR 401.403 Individual deviations. In individual cases, deviations from either the FAR or the AGAR will be authorized only when essential to...
48 CFR 2801.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Individual deviations. 2801... OF JUSTICE ACQUISITION REGULATIONS SYSTEM Deviations From the FAR and JAR 2801.403 Individual deviations. Individual deviations from the FAR or the JAR shall be approved by the head of the...
48 CFR 301.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Individual deviations. 301... ACQUISITION REGULATION SYSTEM Deviations From the FAR 301.403 Individual deviations. Contracting activities shall prepare requests for individual deviations to either the FAR or HHSAR in accordance with 301.470....
48 CFR 1501.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Individual deviations. 1501.403 Section 1501.403 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY GENERAL GENERAL Deviations 1501.403 Individual deviations. Requests for individual deviations from the FAR and...
48 CFR 501.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Individual deviations. 501... Individual deviations. (a) An individual deviation affects only one contract action. (1) The Head of the Contracting Activity (HCA) must approve an individual deviation to the FAR. The authority to grant...
48 CFR 2401.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Individual deviations. 2401... DEVELOPMENT GENERAL FEDERAL ACQUISITION REGULATION SYSTEM Deviations 2401.403 Individual deviations. In individual cases, proposed deviations from the FAR or HUDAR shall be submitted to the Senior...
Allan deviation analysis of financial return series
Hernández-Pérez, R.
2012-05-01
We perform a scaling analysis for the return series of different financial assets applying the Allan deviation (ADEV), which is used in the time and frequency metrology to characterize quantitatively the stability of frequency standards since it has demonstrated to be a robust quantity to analyze fluctuations of non-stationary time series for different observation intervals. The data used are opening price daily series for assets from different markets during a time span of around ten years. We found that the ADEV results for the return series at short scales resemble those expected for an uncorrelated series, consistent with the efficient market hypothesis. On the other hand, the ADEV results for absolute return series for short scales (first one or two decades) decrease following approximately a scaling relation up to a point that is different for almost each asset, after which the ADEV deviates from scaling, which suggests that the presence of clustering, long-range dependence and non-stationarity signatures in the series drive the results for large observation intervals.
Rohlik, Harold E; Wintucky, William T; Scibbe, Herbert W
1957-01-01
Detailed design information including overall performance parameters, velocity diagrams, and blade surface velocities is presented. Experimental performance includes maps based on rating as well as total-pressure ratios showing the effect of exit whirl. Also included are results of surveys at the stator exit and downstream of the rotor at design speed and specific work. This information will be used as a standard for comparison with subsequent secondary-flow work.
POSSIBILISTIC SHARPE RATIO BASED NOVICE PORTFOLIO SELECTION MODELS
Rupak Bhattacharyya
2013-02-01
Full Text Available This paper uses the concept of possibilistic risk aversion to propose a new approach for portfolio selection in fuzzy environment. Using possibility theory, the possibilistic mean, variance, standard deviation and risk premium of a fuzzy number are established. Possibilistic Sharpe ratio is defined as the ratio of possibilistic risk premium and possibilistic standard deviation of a portfolio. The Sharpe ratio is a measure of the performance of the portfolio compared to the risk taken. The higher the Sharpe ratio, the better the performance of the portfolio is and the greater the profits of taking risk. New models of fuzzy portfolio selection considering the possibilistic Sharpe ratio, return and skewness of the portfolio are considered. The feasibility and effectiveness of the proposed method is illustrated by numerical example extracted from Bombay Stock Exchange (BSE, India and is solved by multiple objective genetic algorithm (MOGA.
Meryem Öztürk
2016-10-01
Full Text Available The studies regarding the changes made related to the accounting for lease have taken its final status with the publication of IFRS16 Lease Standard as a result of a long time and effort in January 2016. The related Standard shall ensure (1 the reporting of all the leases in the same way, (2 the displaying of the unrecorded leases in the financial statements and therefore, (3 the submission of more transparent, correct and comparable information. The purpose of our study is to examine the statement of financial position of the lessee enterprise after the transition to the new financial reporting standard IFRS 16 and the impacts of the change in the basic ratios. For this purpose, the impacts possible to occur in the financial position of an airline company having activities in Turkey as a result of the application of the related standard have been examined. The results of the study show that the reflection of the operating leases on the balance sheet shall cause to significant increases in the assets and liabilities and for this reason; there shall be a significant increase in the ratio of liability/asset and a significant decrease return on asset.
Ma, Wenfeng; Zhu, Jinlong; Zeng, Xiangfang; Liu, Xutong; Thacker, Philip; Qiao, Shiyan
2016-01-01
A total of 90 gilts were used to investigate the effects of various standard ileal digestible (SID) total sulfur amino acid (TSAA) to lysine (Lys) ratios on the performance and carcass characteristics of late finishing gilts receiving low crude protein (CP) diets supplemented with crystalline amino acids (CAA). Graded levels of crystalline methionine (Met) (0, 0.3, 0.5, 0.8 or 1.1 g/kg) were added to the basal diet to produce diets providing SID TSAA to Lys ratios of 0.48, 0.53, 0.58, 0.63 or 0.68. At the termination of the experiment, 30 gilts (one pig per pen) with an average body weight (BW) of 120 kg were killed to evaluate carcass traits. Increasing the SID TSAA to Lys ratio increased average daily gain (ADG) (linear and quadratic effect, P < 0.05), improved feed conversion ratio (FCR) (linear and quadratic effect, P < 0.05) and decreased serum urea nitrogen (SUN) concentration (linear and quadratic effect, P < 0.05) of finishing gilts. No effects were obtained for carcass traits. The optimum SID TSAA to Lys ratios to maximize ADG as well as to minimize FCR and SUN levels were 0.57, 0.58 and 0.53 using a linear-break point model and 0.64, 0.62 and 0.61 using a quadratic model. © 2015 Japanese Society of Animal Science.
McNamara, Bruce K.; O’Hara, Matthew J.; Casella, Andrew M.; Carter, Jennifer C.; Addleman, R. Shane; MacFarlan, Paul J.
2016-07-01
Abstract: We report a convenient method for the generation of volatile uranium hexafluoride (UF6) from solid uranium oxides and other uranium compounds, followed by uniform deposition of low levels of UF6 onto sampling coupons. Under laminar flow conditions, UF6 is shown to interact with surfaces within the chamber to a highly predictable degree. We demonstrate the preparation of uranium deposits that range between ~0.01 and 470±34 ng∙cm-2. The data suggest the method can be extended to creating depositions at the sub-picogram∙cm-2 level. Additionally, the isotopic composition of the deposits can be customized by selection of the uranium source materials. We demonstrate a layering technique whereby two uranium solids, each with a different isotopic composition, are employed to form successive layers of UF6 on a surface. The result is an ultra-thin deposit of UF6 that bears an isotopic signature that is a composite of the two uranium sources. The reported deposition method has direct application to the development of unique analytical standards for nuclear safeguards and forensics.
McNamara, Bruce K; O'Hara, Matthew J; Casella, Andrew M; Carter, Jennifer C; Addleman, R Shane; MacFarlan, Paul J
2016-07-01
We report a convenient method for the generation of volatile uranium hexafluoride (UF6) from solid uranium oxides and other U compounds, followed by uniform deposition of low levels of UF6 onto sampling coupons. Under laminar flow conditions, UF6 is shown to interact with surfaces within a fixed reactor geometry to a highly predictable degree. We demonstrate the preparation of U deposits that range between approximately 0.01 and 500ngcm(-2). The data suggest the method can be extended to creating depositions at the sub-picogramcm(-2) level. The isotopic composition of the deposits can be customized by selection of the U source materials and we demonstrate a layering technique whereby two U solids, each with a different isotopic composition, are employed to form successive layers of UF6 on a surface. The result is an ultra-thin deposit that bears an isotopic signature that is a composite of the two U sources. The reported deposition method has direct application to the development of unique analytical standards for nuclear safeguards and forensics. Further, the method allows access to very low atomic or molecular coverages of surfaces.
48 CFR 2501.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Individual deviations. 2501.403 Section 2501.403 Federal Acquisition Regulations System NATIONAL SCIENCE FOUNDATION GENERAL FEDERAL ACQUISITION REGULATIONS SYSTEM Deviations From the FAR 2501.403 Individual deviations....
48 CFR 1901.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Individual deviations. 1901.403 Section 1901.403 Federal Acquisition Regulations System BROADCASTING BOARD OF GOVERNORS GENERAL... Individual deviations. Deviations from the IAAR or the FAR in individual cases shall be authorized by...
48 CFR 201.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Individual deviations. 201.403 Section 201.403 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... Individual deviations. (1) Individual deviations, except those described in 201.402(1) and paragraph (2)...
48 CFR 1.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Individual deviations. 1.403 Section 1.403 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL FEDERAL ACQUISITION REGULATIONS SYSTEM Deviations from the FAR 1.403 Individual deviations....
48 CFR 601.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Individual deviations. 601.403 Section 601.403 Federal Acquisition Regulations System DEPARTMENT OF STATE GENERAL DEPARTMENT OF STATE ACQUISITION REGULATIONS SYSTEM Deviations from the FAR 601.403 Individual deviations....
48 CFR 3401.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Individual deviations. 3401.403 Section 3401.403 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION GENERAL ED ACQUISITION REGULATION SYSTEM Deviations 3401.403 Individual deviations. An...
CALIPSO lidar ratio retrieval over the ocean.
Josset, Damien; Rogers, Raymond; Pelon, Jacques; Hu, Yongxiang; Liu, Zhaoyan; Omar, Ali; Zhai, Peng-Wang
2011-09-12
We are demonstrating on a few cases the capability of CALIPSO to retrieve the 532 nm lidar ratio over the ocean when CloudSat surface scattering cross section is used as a constraint. We are presenting the algorithm used and comparisons with the column lidar ratio retrieved by the NASA airborne high spectral resolution lidar. For the three cases presented here, the agreement is fairly good. The average CALIPSO 532 nm column lidar ratio bias is 13.7% relative to HSRL, and the relative standard deviation is 13.6%. Considering the natural variability of aerosol microphysical properties, this level of accuracy is significant since the lidar ratio is a good indicator of aerosol types. We are discussing dependencies of the accuracy of retrieved aerosol lidar ratio on atmospheric aerosol homogeneity, lidar signal to noise ratio, and errors in the optical depth retrievals. We are obtaining the best result (bias 7% and standard deviation around 6%) for a nighttime case with a relatively constant lidar ratio (in the vertical) indicative of homogeneous aerosol type.
Cole, Stephen R; Lau, Bryan; Eron, Joseph J; Brookhart, M Alan; Kitahata, Mari M; Martin, Jeffrey N; Mathews, William C; Mugavero, Michael J
2015-02-15
There are few published examples of absolute risk estimated from epidemiologic data subject to censoring and competing risks with adjustment for multiple confounders. We present an example estimating the effect of injection drug use on 6-year risk of acquired immunodeficiency syndrome (AIDS) after initiation of combination antiretroviral therapy between 1998 and 2012 in an 8-site US cohort study with death before AIDS as a competing risk. We estimate the risk standardized to the total study sample by combining inverse probability weights with the cumulative incidence function; estimates of precision are obtained by bootstrap. In 7,182 patients (83% male, 33% African American, median age of 38 years), we observed 6-year standardized AIDS risks of 16.75% among 1,143 injection drug users and 12.08% among 6,039 nonusers, yielding a standardized risk difference of 4.68 (95% confidence interval: 1.27, 8.08) and a standardized risk ratio of 1.39 (95% confidence interval: 1.12, 1.72). Results may be sensitive to the assumptions of exposure-version irrelevance, no measurement bias, and no unmeasured confounding. These limitations suggest that results be replicated with refined measurements of injection drug use. Nevertheless, estimating the standardized risk difference and ratio is straightforward, and injection drug use appears to increase the risk of AIDS. © The Author 2014. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
丁悌平; 白瑞梅; 李延河; 万德芳; 邹晓秋; 张青莲
1999-01-01
The absolute 32S/34S ratios of IAEA-S-1 reference material and V-CDT standard are determined. For cross-checking, two sets of synthetic isotope mixtures are prepared from high purity 32S and 34S-enriched materials in different forms: the first set is prepared from BaSO4 whereas the second is prepared from Ag2S. The sulfur isotope analyses are done by using SF6 method with a MAT-251 EM mass spectrometer. The resulting 32S/34S ratio of IAEAS-1 reference material is 22.656 4±0. 006 0, and that of V-CDT is 22. 649 6±0. 006 0.
Teaching Standard Deviation by Building from Student Invention
Day, James; Nakahara, Hiroko; Bonn, Doug
2010-11-01
First-year physics laboratories are often driven by a mix of goals that includes the illustration or discovery of basic physics principles and a myriad of technical skills involving specific equipment, data analysis, and report writing. The sheer number of such goals seems guaranteed to produce cognitive overload, even when highly detailed "cookbook" instructions are given. Recent studies indicate that this approach leaves students with a poor conceptual understanding of one of the most important features of laboratory physics and of the real world of science, in general: the development of an understanding of the nature of measurement and its attendant uncertainty . While students might be able to reproduce certain technical manipulations of data, as novice thinkers they lack the mental scaffolding that allows an expert to organize and apply this knowledge.2,3 Our goal is to put novices on the path to expertise, so that they will be able to transfer their knowledge to novel situations.
Thomson, R M; Rogers, D W O
2010-07-07
Experiments which determine the product of (W/e)air, the average energy deposited per coulomb of charge of one sign released by an electron coming to rest in dry air, and (LDelta/rho)Ca, the Spencer-Attix mean restricted mass collision stopping-power ratio for graphite to air, in a 60Co or 137Cs beam are reanalysed. Correction factors, e.g., to account for gaps about a calorimeter core or perturbations due to a cavity's presence, are calculated using the EGSnrc Monte Carlo code system and these generally decrease the value of (W/e)air(LDelta/rho)Ca for each experiment. Stopping-power ratios are calculated for different choices of density correction and average excitation energy (I-value) for graphite. To calculate an average value (W/e)air(LBIPM/rho)Ca for the BIPM air kerma standard, each experimental result is multiplied by the ratio (LBIPM/rho)Ca/(LDelta/Rho)Ca. While individual values of (LDelta/rho)Ca are sensitive to the I-values and density corrections assumed, this ratio varies by less than 0.1% for different choices. Hence, the product (W/e)air(LBIPM/rho)Ca is relatively insensitive to these choices. The weighted mean of the updated data is (W/e)air(LBIPM/rho)Ca=33.68 J C(-1)+/-0.2%, suggesting that the accepted value of 33.97 J C(-1)+/-0.1% is 0.8% too high. This has implications for primary 60Co air kerma standards worldwide and potentially for the choice of graphite I-value and density correction for the calculation of the graphite stopping power, as well as the value of (W/e)air.
王红; 金煜炜; 陈晓波; 曹延延; 白晋丽; 瞿宇晋; 宋昉
2015-01-01
Objective To analyze the distribution of common chromosomal karyotypes of patients with Turner syndrome (TS), and to explore the correlation between the age and height standard deviation scores (HSDS) on diagnosis.Methods Retrospective investigation was performed for the data of age and HSDS on diagnosis in 273 TS girls(≤ 18.0 years old)diagnosed by chromosomal karyotypes.The main statistical methods were analyzed with t-test and Pearson correlation test by using the SPSS 18.0 statistical software.Results (1) There were 4 kinds of common chromosomal karyotypes in the TS :45, X (87/273 cases,31.9％),46, X, i (Xq) (43/273 cases, 15.7％) ,45, X/46, X, i (Xq) (36/273 cases, 13.2％) and 45, X/46, XX (23/273 cases, 8.4％), respectively, the adolescent TS all had delayed puberty.For the cases with 45, X karyotypes ,3 cases presented mental retardation and 2 cases with organs deformity.(2)The patients with 45 ,X/46,X,i(Xq) karyotypes or with 46,X,i(Xq) karyotypes had the maximum(12.56 age) or the minimum(9.70 age) mean age on diagnosis, respectively, there was a significant difference between 2 groups (t =3.019, P =0.004).The maximum deviation from normal height was found in the patients with karyotypes of 46, X,i (Xq) (HSDS =-4.04), and the minimum deviation was in the patients with karyotypes of 45,X/46, XX (HSDS =-3.16), and there was a significant difference between 2 groups (t =-2.95, P =0.004).(3) More than 75.7％ of TS patients was diagnosed when their heights deviated above 3 SD,and their mean age on diagnosis was 12.10 age,which was 3 years later than those patients within 2 SD.(4) There was a significant negative correlation between the age and HSDS on diagnosis in the groups of common chromosomal karyotypes[45,X、46,X,i(Xq) and 45,X/46,XX] (r =-0.551,-0.560,-0.622,all P ＜ 0.01), except for the group with the 45, X/46, X, i (Xq).Conclusions (1) In this study, the consti-tuent ratios of these 4 common chromosomal karyotypes were different from those in
Liu, X T; Ma, W F; Zeng, X F; Xie, C Y; Thacker, P A; Htoo, J K; Qiao, S Y
2015-10-01
Four 28-d experiments were conducted to determine the standardized ileal digestible (SID) valine (Val) to lysine (Lys) ratio required for 26- to 46- (Exp. 1), 49- to 70- (Exp. 2), 71- to 92- (Exp. 3), and 94- to 119-kg (Exp. 4) pigs fed low CP diets supplemented with crystalline AA. The first 3 experiments utilized 150 pigs (Duroc × Landrace × Large White), while Exp. 4 utilized 90 finishing pigs. Pigs in all 4 experiments were randomly allocated to 1 of 5 diets with 6 pens per treatment (3 pens of barrows and 3 pens of gilts) and 5 pigs per pen for the first 3 experiments and 3 pigs per pen for Exp. 4. Diets for all experiments were formulated to contain SID Val to Lys ratios of 0.55, 0.60, 0.65, 0.70, or 0.75. In Exp. 1 (26 to 46 kg), ADG increased (linear, = 0.039; quadratic, = 0.042) with an increasing dietary Val:Lys ratio. The SID Val:Lys ratio to maximize ADG was 0.62 using a linear broken-line model and 0.71 using a quadratic model. In Exp. 2 (49 to 70 kg), ADG increased (linear, = 0.021; quadratic, = 0.042) as the SID Val:Lys ratio increased. G:F improved (linear, = 0.039) and serum urea nitrogen (SUN) decreased (linear, = 0.021; quadratic, = 0.024) with an increased SID Val:Lys ratio. The SID Val:Lys ratios to maximize ADG as well as to minimize SUN levels were 0.67 and 0.65, respectively, using a linear broken-line model and 0.72 and 0.71, respectively, using a quadratic model. In Exp. 3 (71 to 92 kg), ADG increased (linear, = 0.007; quadratic, = 0.022) and SUN decreased (linear, = 0.011; quadratic, = 0.034) as the dietary SID Val:Lys ratio increased. The SID Val:Lys ratios to maximize ADG as well as to minimize SUN levels were 0.67 and 0.67, respectively, using a linear broken-line model and 0.72 and 0.74, respectively, using a quadratic model. In Exp. 4 (94 to 119 kg), ADG increased (linear, = 0.041) and G:F was improved (linear, = 0.004; quadratic, = 0.005) as the dietary SID Val:Lys ratio increased. The SID Val:Lys ratio to maximize G:F was 0
Chlorine/Bromine Ratios in Fracture-filling Aqueous Alteration Products in Nakhla Olivine
Sutton, S. R.; Rao, M. N.; Dreibus, G.; McKay, D. S.; Waenke, H.; Wentworth, S.; Newville, M.; Trainor, T.; Flynn, G. J.
2002-01-01
The Cl/Br ratios in fracture-filling materials in veins in Nakhla olivine was determined using x-ray microprobe (Br) and EDX (Cl) techniques. The Cl/Br ratio of 55 (standard deviation: 13) shows that the secondary altered material is pristine, extraterrestrial and akin to the Martian soil. Additional information is contained in the original extended abstract.
Xue Lingfeng
2012-03-01
Full Text Available Abstract A total of 335 lactating sows (Landrace × Large White were used in two experiments to determine the optimum ratio of standardized ileal digestible lysine (SID-Lys to metabolizable energy (ME for mixed parity sows during lactation. In Exp. 1, 185 sows (weighing an average of 256.2 ± 6.5 kg and having an average parity of 3.4 ± 0.3 were allocated to one of six experimental diets in a completely randomized block design within parity groups (1, 2, and 3+. The experimental diets were formulated to contain 3.06, 3.16, 3.20, 3.25, 3.30 or 3.40 Mcal/kg of ME and each diet was fed to the sows throughout a 28 day lactation. All diets provided a similar SID-lysine level (0.86%. As a result, the diets provided a SID-Lys:ME ratio of 2.81, 2.72, 2.69, 2.65, 2.61 or 2.53 g/Mcal ME. Sow feed intake was significantly (P P P P P P = 0.02; entire cohort, P P P P P P P = 0.04 were decreased as the SID-Lys:ME ratio of the diet increased. Insulin-like growth factor-1 (P = 0.02, estradiol (P P = 0.02 were increased as the SID-Lys:ME ratio in diet increased. Based on a broken-line model, the estimated SID-Lys:ME ratio to maximize litter weight gain was estimated to be 3.05 g/Mcal.
LARGE DEVIATIONS AND MODERATE DEVIATIONS FOR SUMS OF NEGATIVELY DEPENDENT RANDOM VARIABLES
Liu Li; Wan Chenggao; Feng Yanqin
2011-01-01
In this article, we obtain the large deviations and moderate deviations for negatively dependent (ND) and non-identically distributed random variables defined on (-∞, +∞). The results show that for some non-identical random variables, precise large deviations and moderate deviations remain insensitive to negative dependence structure.
Li Pengfei
2012-03-01
Full Text Available Abstract A total of 2,121 growing-finishing pigs (Duroc × Landrace × Large White were utilized in six experiments conducted to determine the effects of different ratios of standardized ileal digestible lysine (SID-Lys to metabolizable energy (ME on the performance and carcass characteristics of growing-finishing pigs. Exps. 1 (30 to 50 kg, 2 (52 to 70 kg and 3 (81 to 104 kg were conducted to find an optimum ME level and then this level was used in Exps. 4 (29 to 47 kg, 5 (54 to 76 kg and 6 (84 to 109 kg to test the response of pigs to different ratios of SID-Lys:ME. In Exps.1 to 3, four treatments were used consisting of diets with a formulated ME content of 3.1, 3.2, 3.3 or 3.4 in Exps. 1 and 2 while Exp. 3 used 3.05, 3.15, 3.25 or 3.35 Mcal/kg. A constant SID-Lys:ME ratio of 2.6, 2.3 or 2.0 g/Mcal was used in Exps. 1, 2 and 3, respectively. Weight gain was significantly increased with increasing energy level in Exp.1 while weight gain was unaltered in Exps. 2 and 3. For all three experiments, feed intake was decreased (P P P P P P
Vanderstichele, Hugo Marcel Johan; Janelidze, Shorena; Demeyer, Leentje; Coart, Els; Stoops, Erik; Herbst, Victor; Mauroo, Kimberley; Brix, Britta; Hansson, Oskar
2016-01-01
Background: Reduced cerebrospinal fluid (CSF) concentration of amyloid-β1-42 (Aβ1-42) reflects the presence of amyloidopathy in brains of subjects with Alzheimer’s disease (AD). Objective: To qualify the use of Aβ1-42/Aβ1-40 for improvement of standard operating procedures (SOP) for measurement of CSF Aβ with a focus on CSF collection, storage, and analysis. Methods: Euroimmun ELISAs for CSF Aβ isoforms were used to set up a SOP with respect to recipient properties (low binding, polypropylene), volume of tubes, freeze/thaw cycles, addition of detergents (Triton X-100, Tween-20) in collection or storage tubes or during CSF analysis. Data were analyzed with linear repeated measures and mixed effects models. Results: Optimization of CSF analysis included a pre-wash of recipients (e.g., tubes, 96-well plates) before sample analysis. Using the Aβ1-42/Aβ1-40 ratio, in contrast to Aβ1-42, eliminated effects of tube type, additional freeze/thaw cycles, or effect of CSF volumes for polypropylene storage tubes. ‘Low binding’ tubes reduced the loss of Aβ when aliquoting CSF or in function of additional freeze/thaw cycles. Addition of detergent in CSF collection tubes resulted in an almost complete absence of variation in function of collection procedures, but affected the concentration of Aβ isoforms in the immunoassay. Conclusion: The ratio of Aβ1-42/Aβ1-40 is a more robust biomarker than Aβ1-42 toward (pre-) analytical interfering factors. Further, ‘low binding’ recipients and addition of detergent in collection tubes are able to remove effects of SOP-related confounding factors. Integration of the Aβ1-42/Aβ1-40 ratio and ‘low-binding tubes’ into guidance criteria may speed up worldwide standardization of CSF biomarker analysis. PMID:27258423
Ensemble standar deviation of wind speed and direction of the FDDA input to WRF
U.S. Environmental Protection Agency — NetCDF file of the SREF standard deviation of wind speed and direction that was used to inject variability in the FDDA input. variable U_NDG_OLD contains standard...
Mathai, J K; Htoo, J K; Thomson, J E; Touchette, K J; Stein, H H
2016-10-01
Four experiments were conducted to determine effects of fiber on the ideal Thr:Lys ratio for 25- to 50-kg gilts. In Exp. 1, the objective was to determine the requirement for standardized ileal digestible Lys for gilts from 25 to 50 kg BW. Seventy gilts (24.54 ± 3.28 kg BW) were used in a growth assay with 2 pigs per pen, 5 diets, and 7 replicate pens per diet. The 5 diets were based on corn and soybean meal and contained between 0.80 and 1.32% SID Lys. Results indicated that 1.09% SID Lys was needed to optimize ADG and G:F. In Exp. 2, the objective was to determine the standardized ileal digestibility of AA in corn, soybean meal, field peas, fish meal, and soybean hulls. Six ileal-cannulated gilts (26.5 ± 0.74 kg BW) were allotted to a 6 × 6 Latin square design with 6 diets and 6 periods. Values for standardized ileal digestibility of AA were calculated for all ingredients. In Exp. 3, the objective was to determine the effect of fiber on the ideal SID Thr:Lys ratio for gilts from 25 to 50 kg BW. A total of 192 gilts (26.29 ± 4.64 kg BW) were used in a growth assay with 2 pigs per pen and 8 replicate pens per treatment. Six low-fiber diets and 6 high-fiber diets were formulated using the same batches of ingredients as in Exp. 2. Within each level of fiber, diets with SID Thr:Lys ratios ranging from 45:100 to 90:100 were formulated using the SID values calculated in Exp. 2. In both types of diets, ADG and G:F linearly and quadratically ( fiber diets and at 0.71 and 0.63, respectively, for pigs fed high-fiber diets. In Exp. 4, the objective was to determine the N balance in pigs fed low-fiber or high-fiber diets that were formulated to have SID Thr:Lys ratios of 45:100 or 60:100. The 4 diets were formulated using the same batches of ingredients as in Exp. 2, and the SID values determined in Exp. 2 were used in diet formulations. Thirty-six gilts (29.0 ± 0.74 kg BW) were individually housed in metabolism crates with 9 replicate pigs per diet. Retention of N (% of
48 CFR 1201.403 - Individual deviations.
2010-10-01
...) 48 CFR 1.405(e) applies). However, see TAM 1201.403. ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Individual deviations... FEDERAL ACQUISITION REGULATIONS SYSTEM 70-Deviations From the FAR and TAR 1201.403 Individual...
48 CFR 1401.403 - Individual deviations.
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Individual deviations. 1401.403 Section 1401.403 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL DEPARTMENT OF THE INTERIOR ACQUISITION REGULATION SYSTEM Deviations from the FAR and DIAR 1401.403...
48 CFR 3001.403 - Individual deviations.
2010-10-01
.... 3001.403 Section 3001.403 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY... from the FAR and HSAR 3001.403 Individual deviations. Unless precluded by law, executive order, or..., including complete documentation of the justification for the deviation (See HSAM 3001.403)....
2010-07-01
... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Deviation. 101-1.110 Section 101-1.110 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 1-INTRODUCTION 1.1-Regulation System § 101-1.110 Deviation...
2010-04-01
... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Deviations. 435.4 Section 435.4 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH... General § 435.4 Deviations. The Office of Management and Budget (OMB) may grant exceptions for classes...
On the applicability of the geodesic deviation equation in General Relativity
Philipp, Dennis; Laemmerzahl, Claus
2016-01-01
Within the theory of General Relativity we study the solution and range of applicability of the standard geodesic deviation equation in highly symmetric spacetimes. The deviation equation is used to model satellite orbit constellations around the earth. In particular, we reconsider the deviation equation in Newtonian gravity and then determine relativistic effects within the theory of General Relativity. The deviation of nearby orbits, as constructed from exact solutions of the underlying geodesic equation, is compared to the solution of the geodesic deviation equation to assess the accuracy of the latter. Furthermore, we comment on the so-called Shirokov effect in Schwarzschild spacetime.
Sait Eser KARLIK
2016-10-01
Full Text Available In this paper, variation of the signal-to-crosstalk ratio (SXR due to effects of four-wave mixing (FWM has been analyzed on center channels of 5-, 7-, 9-channel dense wavelength division multiplexing (DWDM systems implemented with G.652 standard single-mode fibers (SSMFs for 12.5 GHz, 25 GHz, 50 GHz and 100 GHz equal channel spacing values. Center channels on such systems are the most severely impacted channels by FWM. Therefore, results obtained are the worst-case values for the DWDM system performance and important for system design. Simulations have been performed for systems using three different commercially available SMFs having different design parameter values for chromatic dispersion, dispersion slope, nonlinearity coefficient and attenuation coefficient which are all in the scope of the G.652 Recommendation of Telecommunication Standardization Sector of International Telecommunication Union (ITU-T for SSMFs. In those simulations, under the impact of FWM, variation of SXR with variations in input powers, channel spacings and link lengths have been observed. Simulation results display the combined effect of the optical fiber and system design parameters on FWM performance of DWDM systems and give important clues for not only long-haul but also access network implementations of DWDM systems.
Large Deviations in Quantum Spin Chain
Ogata, Yoshiko
2008-01-01
We show the full large deviation principle for KMS-states and $C^*$-finitely correlated states on a quantum spin chain. We cover general local observables. Our main tool is Ruelle's transfer operator method.
Large deviations for a random speed particle
Lefevere, Raphael; Zambotti, Lorenzo
2011-01-01
We investigate large deviations for the empirical measure of the position and momentum of a particle traveling in a box with hot walls. The particle travels with uniform speed from left to right, until it hits the right boundary. Then it is absorbed and re-emitted from the left boundary with a new random speed, taken from an i.i.d. sequence. It turns out that this simple model, often used to simulate a heat bath, displays unusually complex large deviations features, that we explain in detail. In particular, if the tail of the update distribution of the speed is sufficiently oscillating, then the empirical measure does not satisfy a large deviations principle, and we exhibit optimal lower and upper large deviations functionals.
On geodesic deviation in Schwarzschild spacetime
Philipp, Dennis; Laemmerzahl, Claus; Deshpande, Kaustubh
2015-01-01
For metrology, geodesy and gravimetry in space, satellite based instruments and measurement techniques are used and the orbits of the satellites as well as possible deviations between nearby ones are of central interest. The measurement of this deviation itself gives insight into the underlying structure of the spacetime geometry, which is curved and therefore described by the theory of general relativity (GR). In the context of GR, the deviation of nearby geodesics can be described by the Jacobi equation that is a result of linearizing the geodesic equation around a known reference geodesic with respect to the deviation vector and the relative velocity. We review the derivation of this Jacobi equation and restrict ourselves to the simple case of the spacetime outside a spherically symmetric mass distribution and circular reference geodesics to find solutions by projecting the Jacobi equation on a parallel propagated tetrad as done by Fuchs. Using his results, we construct solutions of the Jacobi equation for...
Large deviations for fractional Poisson processes
Beghin, Luisa
2012-01-01
We present large deviation results for two versions of fractional Poisson processes: the main version which is a renewal process, and the alternative version where all the random variables are weighted Poisson distributed. We also present a sample path large deviation result for suitably normalized counting processes; finally we show how this result can be applied to the two versions of fractional Poisson processes considered in this paper.
The large deviations theorem and ergodicity
Gu Rongbao [School of Finance, Nanjing University of Finance and Economics, Nanjing 210046 (China)
2007-12-15
In this paper, some relationships between stochastic and topological properties of dynamical systems are studied. For a continuous map f from a compact metric space X into itself, we show that if f satisfies the large deviations theorem then it is topologically ergodic. Moreover, we introduce the topologically strong ergodicity, and prove that if f is a topologically strongly ergodic map satisfying the large deviations theorem then it is sensitively dependent on initial conditions.
2012-01-01
A total of 335 lactating sows (Landrace × Large White) were used in two experiments to determine the optimum ratio of standardized ileal digestible lysine (SID-Lys) to metabolizable energy (ME) for mixed parity sows during lactation. In Exp. 1, 185 sows (weighing an average of 256.2 ± 6.5 kg and having an average parity of 3.4 ± 0.3) were allocated to one of six experimental diets in a completely randomized block design within parity groups (1, 2, and 3+). The experimental diets were formulated to contain 3.06, 3.16, 3.20, 3.25, 3.30 or 3.40 Mcal/kg of ME and each diet was fed to the sows throughout a 28 day lactation. All diets provided a similar SID-lysine level (0.86%). As a result, the diets provided a SID-Lys:ME ratio of 2.81, 2.72, 2.69, 2.65, 2.61 or 2.53 g/Mcal ME. Sow feed intake was significantly (P sow parity. Using regression analysis, feed intake was shown to be maximized at 3.25, 3.21, 3.21 and 3.21 Mcal/kg of ME for parity 1, 2, 3+ sows and the entire cohort of sows respectively (quadratic; P sows and the entire cohort (P sows (weighing 254.6 ± 7.3 kg and having an average parity of 3.4 ± 0.4) were allocated to one of five treatments in a completely randomized block design within parity (1, 2, and 3+). The experimental diets were formulated to contain 2.1, 2.4, 2.7, 3.0 or 3.3 g/Mcal of SID-Lys:ME ratio with all diets providing 3.25 Mcal/kg of ME. The diets were fed to the sows throughout a 28 day lactation. Sow body weight loss was affected by dietary treatment (parity 3+ sows, P = 0.02; entire cohort, P sow parity (P sows and the entire cohort (P sow parity (P < 0.01). Plasma urea nitrogen (P < 0.01), creatinine (P < 0.01) and non-esterifide fatty acids (P = 0.04) were decreased as the SID-Lys:ME ratio of the diet increased. Insulin-like growth factor-1 (P = 0.02), estradiol (P < 0.01) and luteinizing hormone (P = 0.02) were increased as the SID-Lys:ME ratio in diet increased. Based on a broken-line model, the estimated SID-Lys:ME ratio to
Search for SM deviations in top precision studies at CMS
Skovpen, Kirill
2017-01-01
Precision studies of top quark properties provide a unique playground to test the predictions of the standard model and to search for new physics. Reviewed results from the CMS experiment done with the data collected at 8 TeV include studies of top quark Wtb anomalous and FCNC couplings, polarization, CP-violation and spin correlation effects. No significant deviations from the SM predictions are observed.
Anterior septal deviation and contralateral alar collapse.
Schalek, P; Hahn, A
2011-01-01
Septal deviation is often found in conjunction with other pathological conditions that adversely affect nasal patency. Anterior septal deviation, together with contralateral alar collapse, is a relatively rare type of anatomical and functional incompetence. In our experience, it can often be resolved with septoplasty, without the necessity of surgery involving the external valve. The aim of this paper was to verify this hypothesis prospectively. Twelve patients with anterior septal deviation and simultaneous alar collapse on the opposite side were prospectively enrolled in the study. Subjective assessment of nasal patency was made on post-operative day 1, and again 6 months after surgery, using a subjective evaluation of nasal breathing. The width of the nostril (alar-columellar distance) on the side with the alar collapse was measured during inspiration pre-operatively, 1 day after surgery and again 6 months after surgery. Immediately after surgery, all patients reported improved or excellent nasal breathing on the side of the original septal deviation. On the collapsed side, one patient reported no change in condition. With the exception of one patient, all measurements showed some degree of improvement in the extension of the alar-columellar distance. The average benefit 6 months after surgery was an improvement of 4.54 mm. In our group of patients (anterior septal deviation and simultaneous contralateral alar collapse and no obvious structural changes of the alar cartilage) we found septoplasty to be entirely suitable and we recommend it as the treatment of choice in such cases.
Investigating deviations from norms in court interpreting
Dubslaff, Friedel; Martinsen, Bodil
, in some cases, all - professional users involved (judges, lawyers, prosecutors). As far as the non-Danish speaking users are concerned, it has, with one notable exception, unfortunately not been possible to obtain data from this group via questionnaires. As this type of data, however, is important...... behaviour, explore why the deviations in question occur, find out what happens if deviations are perceived as such by the other participants involved in the interpreted event. We will reconstruct the norms in question by examining interpreters' and (mainly) professional users' behaviour in the course...... deviations and sanctions in every case. By way of example: Several judges, who had given their consent to recordings of authentic data in connection with the research project, reported that they had experienced problems with insufficient language proficiency on the part of untrained interpreters speaking...
On large deviations for ensembles of distributions
Khrychev, D. A.
2013-11-01
The paper is concerned with the large deviations problem in the Freidlin-Wentzell formulation without the assumption of the uniqueness of the solution to the equation involving white noise. In other words, it is assumed that for each \\varepsilon>0 the nonempty set \\mathscr P_\\varepsilon of weak solutions is not necessarily a singleton. Analogues of a number of concepts in the theory of large deviations are introduced for the set \\{\\mathscr P_\\varepsilon,\\,\\varepsilon>0\\}, hereafter referred to as an ensemble of distributions. The ensembles of weak solutions of an n-dimensional stochastic Navier-Stokes system and stochastic wave equation with power-law nonlinearity are shown to be uniformly exponentially tight. An idempotent Wiener process in a Hilbert space and idempotent partial differential equations are defined. The accumulation points in the sense of large deviations of the ensembles in question are shown to be weak solutions of the corresponding idempotent equations. Bibliography: 14 titles.
PoDMan: Policy Deviation Management
Aishwarya Bakshi
2017-07-01
Full Text Available Whenever an unexpected or exceptional situation occurs, complying with the existing policies may not be possible. The main objective of this work is to assist individuals and organizations to decide in the process of deviating from policies and performing a non-complying action. The paper proposes utilizing software agents as supportive tools to provide the best non-complying action while deviating from policies. The article also introduces a process in which the decision on the choice of non-complying action can be made. The work is motivated by a real scenario observed in a hospital in Norway and demonstrated through the same settings.
ZHANG Hui; ZHANG Shu-Yi; FAN Li
2009-01-01
A model of high-overtone bulk acoustic resonators is used to study the effects of thickness deviation of elastic plates on resonance frequency spectra in planar multi-layered systems. The resonance frequency shifts induced by the thickness deviations of the elastic plates periodically vary with the resonance order, which depends on the acoustic impedance ratios of the elastic plates to piezoelectric patches. Additionally, the center lines of the frequency shift oscillations Hnearly change with the orders of the resonance modes, and their slopes are sensitive to the thickness deviations of the plates, which can be used to quantitatively evaluate the thickness deviations.
21 CFR 600.14 - Reporting of biological product deviations by licensed manufacturers.
2010-04-01
... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Reporting of biological product deviations by... HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS BIOLOGICAL PRODUCTS: GENERAL Establishment Standards § 600.14 Reporting of biological product deviations by licensed manufacturers. (a) Who must report...
Bodily Deviations and Body Image in Adolescence
Vilhjalmsson, Runar; Kristjansdottir, Gudrun; Ward, Dianne S.
2012-01-01
Adolescents with unusually sized or shaped bodies may experience ridicule, rejection, or exclusion based on their negatively valued bodily characteristics. Such experiences can have negative consequences for a person's image and evaluation of self. This study focuses on the relationship between bodily deviations and body image and is based on a…
Bodily Deviations and Body Image in Adolescence
Vilhjalmsson, Runar; Kristjansdottir, Gudrun; Ward, Dianne S.
2012-01-01
Adolescents with unusually sized or shaped bodies may experience ridicule, rejection, or exclusion based on their negatively valued bodily characteristics. Such experiences can have negative consequences for a person's image and evaluation of self. This study focuses on the relationship between bodily deviations and body image and is based on a…
2010-10-01
... 45 Public Welfare 4 2010-10-01 2010-10-01 false Deviations. 2543.4 Section 2543.4 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General...
Voice Deviations and Coexisting Communication Disorders.
St. Louis, Kenneth O.; And Others
1992-01-01
This study examined the coexistence of other communicative disorders with voice disorders in about 3,400 children in grades 1-12 at 100 sites throughout the United States. The majority of voice-disordered children had coexisting articulation deviations and also differed from controls on two language measures and mean pure-tone hearing thresholds.…
41 CFR 109-1.5304 - Deviations.
2010-07-01
... Secretary for Procurement and Assistance Management. A HFO's decision not to provide life-cycle control... through the cognizant HFO to the Deputy Assistant Secretary for Procurement and Assistance Management. ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Deviations....
2010-10-01
... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Deviations. 12.904 Section 12.904 Public Lands: Interior Office of the Secretary of the Interior ADMINISTRATIVE AND AUDIT REQUIREMENTS AND COST PRINCIPLES FOR ASSISTANCE PROGRAMS Uniform Administrative Requirements for Grants and Agreements...
Otsubo, Koichi; Yamaoka, Kazue; Yokoyama, Tetsuji; Takahashi, Kunihiko; Nishikawa, Masako; Tango, Toshiro
2009-02-01
The standardized mortality ratio (SMR) is frequently used to compare health status among different populations. However, SMR could be biased when based upon communities with small population size such as towns and wards and comparison of SMRs in such cases is not appropriate. The "empirical Bayes estimate of standardized mortality ratio" (EBSMR) is a useful alternative index for comparing mortalities among small populations. The objective of the present study was to use the EBSMR to clarify the relationships between health care resources and mortalities in 3,360 municipalities in Japan. Health care resource data (number of physicians, number of general clinics, number of general sickbeds, and number of emergency hospitals) and socioeconomic factors (population, birth rate, aged households, marital rate, divorce rate, taxable income per individual under taxes duty, unemployment, secondary, tertiary industrial employment and prefecture) were obtained from officially published reports. EBSMRs for all causes, cerebrovascular disease, heart disease, acute myocardial infarction, and malignant neoplasms were calculated from the 1997-2001 vital statistic records. Multiple regression analysis was used to examine the relationships between EBSMRs and the variables representing health care resources and socioeconomic factors as covariates. Some of the variables were log-transformed to normalize the distribution of variables. The correlation between number of physicians and general sickbeds was very high (Pearson's r = 0.776). So, we excluded the number of general sickbeds. Some of the EBSMRs were inversely associated with the number of physicians per person (all causes in males (beta = -0.042, P = 0.024) and females (beta = -0.150, P < 0.001), cerebrovascular disease in females (beta = -0.074, P < 0.001), heart disease in males (beta = -0.066, P < 0.001) and females (beta = - 0.087, P < 0.001), acute myocardial infarction in females (beta = -0.061, P = 0.003), and malignant
Alhdiri, Maryam Ahmed; Samat, Nor Azah; Mohamed, Zulkifley
2017-03-01
Cancer is the most rapidly spreading disease in the world, especially in developing countries, including Libya. Cancer represents a significant burden on patients, families, and their societies. This disease can be controlled if detected early. Therefore, disease mapping has recently become an important method in the fields of public health research and disease epidemiology. The correct choice of statistical model is a very important step to producing a good map of a disease. Libya was selected to perform this work and to examine its geographical variation in the incidence of lung cancer. The objective of this paper is to estimate the relative risk for lung cancer. Four statistical models to estimate the relative risk for lung cancer and population censuses of the study area for the time period 2006 to 2011 were used in this work. They are initially known as Standardized Morbidity Ratio, which is the most popular statistic, which used in the field of disease mapping, Poisson-gamma model, which is one of the earliest applications of Bayesian methodology, Besag, York and Mollie (BYM) model and Mixture model. As an initial step, this study begins by providing a review of all proposed models, which we then apply to lung cancer data in Libya. Maps, tables and graph, goodness-of-fit (GOF) were used to compare and present the preliminary results. This GOF is common in statistical modelling to compare fitted models. The main general results presented in this study show that the Poisson-gamma model, BYM model, and Mixture model can overcome the problem of the first model (SMR) when there is no observed lung cancer case in certain districts. Results show that the Mixture model is most robust and provides better relative risk estimates across a range of models. Creative Commons Attribution License
Alhdiri, Maryam Ahmed; Samat, Nor Azah; Mohamed, Zulkifley
2017-01-01
Cancer is the most rapidly spreading disease in the world, especially in developing countries, including Libya. Cancer represents a significant burden on patients, families, and their societies. This disease can be controlled if detected early. Therefore, disease mapping has recently become an important method in the fields of public health research and disease epidemiology. The correct choice of statistical model is a very important step to producing a good map of a disease. Libya was selected to perform this work and to examine its geographical variation in the incidence of lung cancer. The objective of this paper is to estimate the relative risk for lung cancer. Four statistical models to estimate the relative risk for lung cancer and population censuses of the study area for the time period 2006 to 2011 were used in this work. They are initially known as Standardized Morbidity Ratio, which is the most popular statistic, which used in the field of disease mapping, Poisson-gamma model, which is one of the earliest applications of Bayesian methodology, Besag, York and Mollie (BYM) model and Mixture model. As an initial step, this study begins by providing a review of all proposed models, which we then apply to lung cancer data in Libya. Maps, tables and graph, goodness-of-fit (GOF) were used to compare and present the preliminary results. This GOF is common in statistical modelling to compare fitted models. The main general results presented in this study show that the Poisson-gamma model, BYM model, and Mixture model can overcome the problem of the first model (SMR) when there is no observed lung cancer case in certain districts. Results show that the Mixture model is most robust and provides better relative risk estimates across a range of models. PMID:28440974
Laurent, D; Authier, B; Lebas, J F; Rossi, A
1992-01-01
Seven subjects underwent a standard localized exercise of calf muscles in order to investigate whether the metabolic exercise-induced steady-state, as revealed by the evaluation of inorganic phosphate/phosphocreatine ratio, depends on the conditioning of the muscle just prior to the exercise. The experimental protocols consisted of two separate experiments using first [31P]nuclear magnetic resonance spectroscopy and second (on 3 subjects) infrared oxyphotometry to respectively follow variation of energy metabolism and tissular deoxygenation. The exercise consisted of 240 successive plantar flexions (0.5 Hz frequency) against a high load equivalent to 80% of the maximal voluntary contraction. This exercise was accomplished before cold exercise and after warm exercise, a warming-up period bringing to approximately 50% of VO2max. The results showed that: (1) steady-state level of phosphate/phosphocreatine and intracellular acidosis was significantly lowered by warming-up; (2) cold and warm exercise steady-state of calculated adenosine diphosphate values were not significantly different; (3) cold exercise rapidly induced a high tissular deoxygenation that is not observed during warm exercise; and (4) time-constant of phosphocreatine resynthesis is lowered after warm exercise but the initial slope of time-evolution is not modified. Parallel experiments also showed that phosphate/phosphocreatine steady-state was not modified in comparison with warm exercise when the same power of exercise was reached by stepwise incrementation of the charge. From these results we postulate that a better tissue oxygenation due to a global or localized warming-up allows to reach the same mechanical performance with a lower decrease of PCr content, owing to a faster adjustment of oxidative metabolism during the transitional period.(ABSTRACT TRUNCATED AT 250 WORDS)
Jodra, V Monge; Rodela, A Robustillo; Martínez, E Martín; Fresneña, N López
2003-10-01
To compare Spanish surgical wound infection (SWI) rates for three procedures with those published by the U.S. NNIS System, and to analyze quarterly trends. This was a 4-year prospective analysis of SWI using data from a Spanish nosocomial infection surveillance network based on CDC classification criteria. SWI rates were computed as standardized infection ratios (SIRs). Trends for both SWIs and SIRs were evaluated by linear regression. Forty-three Spanish hospitals during 1997 through 2000. Those undergoing cholecystectomy (n = 7,631), appendectomy (n = 5,780), and herniorrhaphy (n = 9,864). For cholecystectomy patients, the SWI rate was 4.38% and the SIR was 3.32. Both of these variables showed a slightly rising, although nonsignificant, linear trend during the study period. For appendectomy patients, the SWI rate was 7.94% and the SIR was 2.86. The linear trend was increasing for both, but only the SWI rate attained significance. For herniorrhaphy patients, the SWI rate was 1.77% and the SIR was 1.64. Both of these variables showed a significant descending tendency during the 4 years. Because the SIR takes into account the patient risk category, it is the best indicator of the trend shown by the SWI rate over time for a given surgical procedure. According to our comparison of SIRs with reference NNIS System values, SWI rates for cholecystectomy and appendectomy were high. Monitoring of the SIR will provide a basis for the design of infection control measures and the assessment of their effectiveness.
Exact Moderate and Large Deviations for Linear Processes
Peligrada, Magda; Zhong, Yunda; Wu, Wei Biao
2011-01-01
Large and moderate deviation probabilities play an important role in many applied areas, such as insurance and risk analysis. This paper studies the exact moderate and large deviation asymptotics in non-logarithmic form for linear processes with independent innovations. The linear processes we analyze are general and therefore they include the long memory case. We give an asymptotic representation for probability of the tail of the normalized sums and specify the zones in which it can be approximated either by a standard normal distribution or by the marginal distribution of the innovation process. The results are then applied to regression estimates, moving averages, fractionally integrated processes, linear processes with regularly varying exponents and functions of linear processes. We also consider the computation of value at risk and expected shortfall, fundamental quantities in risk theory and finance.
Moderate Deviation Principle for dynamical systems with small random perturbation
ma, Yutao; Wu, Liming
2011-01-01
Consider the stochastic differential equation in $\\rr^d$ dX^{\\e}_t&=b(X^{\\e}_t)dt+\\sqrt{\\e}\\sigma(X^\\e_t)dB_t X^{\\e}_0&=x_0,\\quad x_0\\in\\rr^d where $b:\\rr^d\\rightarrow\\rr^d$ is $C^1$ such that $ \\leq C(1+|x|^2)$, $\\sigma:\\rr^d\\rightarrow \\MM(d\\times n)$ is locally Lipschitzian with linear growth, and $B_t$ is a standard Brownian motion taking values in $\\rr^n$. Freidlin-Wentzell's theorem gives the large deviation principle for $X^\\e$ for small $\\e$. In this paper we establish its moderate deviation principle.
Association between septal deviation and sinonasal papilloma.
Nomura, Kazuhiro; Ogawa, Takenori; Sugawara, Mitsuru; Honkura, Yohei; Oshima, Hidetoshi; Arakawa, Kazuya; Oshima, Takeshi; Katori, Yukio
2013-12-01
Sinonasal papilloma is a common benign epithelial tumor of the sinonasal tract and accounts for 0.5% to 4% of all nasal tumors. The etiology of sinonasal papilloma remains unclear, although human papilloma virus has been proposed as a major risk factor. Other etiological factors, such as anatomical variations of the nasal cavity, may be related to the pathogenesis of sinonasal papilloma, because deviated nasal septum is seen in patients with chronic rhinosinusitis. We, therefore, investigated the involvement of deviated nasal septum in the development of sinonasal papilloma. Preoperative computed tomography or magnetic resonance imaging findings of 83 patients with sinonasal papilloma were evaluated retrospectively. The side of papilloma and the direction of septal deviation showed a significant correlation. Septum deviated to the intact side in 51 of 83 patients (61.4%) and to the affected side in 18 of 83 patients (21.7%). Straight or S-shaped septum was observed in 14 of 83 patients (16.9%). Even after excluding 27 patients who underwent revision surgery and 15 patients in whom the papilloma touched the concave portion of the nasal septum, the concave side of septal deviation was associated with the development of sinonasal papilloma (p = 0.040). The high incidence of sinonasal papilloma in the concave side may reflect the consequences of the traumatic effects caused by wall shear stress of the high-velocity airflow and the increased chance of inhaling viruses and pollutants. The present study supports the causative role of human papilloma virus and toxic chemicals in the occurrence of sinonasal papilloma.
张凯; 董华英
2013-01-01
A new method for discriminating the inrush current by integrating the characteristics of the two kinds of current is presented based on large of simulation and testing.Because of the character that the magnetic inrush current leans to the one side of the time axis and the internal fault current is similar to the sine wave,the difference between the maximum and minimum and the unitary area in cycle is used as a general criterion to discriminate the unsymmetrical inrush current.For the symmetrical inrush current,we set a second criterion,which needs to calculate the average standard deviation of the 2-norm between the part data in the half cycle and the sine wave with the same length.validity of the new method is verified with simulating and testing.%在大量仿真和实验的基础上,综合变压器励磁涌流和内部故障电流的特点,提出了一种鉴别变压器励磁涌流的新方法.该方法基于励磁涌流偏于时间轴一侧和故障电流接近正弦波的特点,以周波内最值差别和归一化面积作为综合判据鉴别非对称的励磁涌流,而对于对称的励磁涌流,以后半周波内一部分数据与同窗长的标准正弦波的2-范数的平均标准差作为判据进行鉴别.仿真和实验验证了方法的正确性.
邱桂华
2013-01-01
Cloud computing is the focus at present in the field of information technology , and the cloud platform covert channel is a new safety problem caused by the infrastructure of cloud computing platform .The covert channel in cloud platform will leak the confidential information of cloud customers , seriously damages the safety of cloud platform .We summarise the correlative works of the covert channel detection, aiming at the cloud platform covert channel based on CPU response time , we abstract its model, and put forward at the first time a detection method with hybrid indicators of the integration of entropy and standard deviation .Experimental results show that this detection method can reach a false positive rate less than 5%, therefore has good detection performance .%云计算是目前信息技术领域研究的热点，而云平台隐蔽信道是由云计算平台的基础架构导致的新的安全问题。云平台隐蔽信道会泄漏云客户的机密信息，严重危害云平台安全。总结隐蔽信道检测的相关工作，并针对基于CPU响应时间的云平台隐蔽信道，抽象云平台隐蔽信道模型，首次提出融合熵率和标准差混合指标的检测方法。实验结果表明使用该检测方法能够达到低于5％的误报率，具有很好的检测性能。
Habibollah Ghassemzadeh
1994-06-01
Full Text Available The Bender-Gestalt Test was given to thirty mentally-retarded psychiatric patients. The mean, standard deviation, and standard error were 56.73, 26.25, and 4.80 respectively. Rotation was the most frequent major deviation which occurred in all the designs."nDesign # 7 was the most difficult one to be reproduced in the sample. This design by itself, was subject to 47% of distortion, 79% of omission, and 21% of rotation.
Large Deviation Strategy for Inverse Problem
Ojima, Izumi
2011-01-01
Taken traditionally as a no-go theorem against the theorization of inductive processes, Duheme-Quine thesis may interfere with the essence of statistical inference. This difficulty can be resolved by \\textquotedblleft Micro-Macro duality\\textquotedblright\\ \\cite{Oj03, Oj05} which clarifies the importance of specifying the pertinent aspects and accuracy relevant to concrete contexts of scientific discussions and which ensures the matching between what to be described and what to describe in the form of the validity of duality relations. This consolidates the foundations of the inverse problem, induction method, and statistical inference crucial for the sound relations between theory and experiments. To achieve the purpose, we propose here Large Deviation Strategy (LDS for short) on the basis of Micro-Macro duality, quadrality scheme, and large deviation principle. According to the quadrality scheme emphasizing the basic roles played by the dynamics, algebra of observables together with its representations and ...
Deviations from LTE in a stellar atmosphere
Kalkofen, W.; Klein, R. I.; Stein, R. F.
1979-01-01
Deviations for LTE are investigated in an atmosphere of hydrogen atoms with one bound level, satisfying the equations of radiative, hydrostatic, and statistical equilibrium. The departure coefficient and the kinetic temperature as functions of the frequency dependence of the radiative cross section are studied analytically and numerically. Near the outer boundary of the atmosphere, the departure coefficient is smaller than unity when the radiative cross section grows with frequency faster than with the square of frequency; it exceeds unity otherwise. Far from the boundary the departure coefficient tends to exceed unity for any frequency dependence of the radiative cross section. Overpopulation always implies that the kinetic temperature in the statistical-equilibrium atmosphere is higher than the temperature in the corresponding LTE atmosphere. Upper and lower bounds on the kinetic temperature are given for an atmosphere with deviations from LTE only in the optically shallow layers when the emergent intensity can be described by a radiation temperature.
Detecting deviations from pure EOF during CE separations.
O'Grady, John F; Noonan, Kathryn Y; McDonnell, Patrick; Mancuso, Aaron J; Frederick, Kimberley A
2007-07-01
CE separations are known for their high separation efficiencies. In systems with EOF, the high efficiencies benefit from the flat, plug profile that is characteristic of EOF. When a velocity gradient is present, such as in separations which have nonuniform buffer ionic strength, surface adsorption or differences in the height of the ends of the capillary, a parabolic flow component is introduced. This deviation from purely EOF yields increased peak dispersion and a subsequent decrease in separation performance. This work details a rapid method for detecting deviations from ideal plug flow during the course of a separation using the radially averaged flow profile of a photobleached fluorophore added to the BGE. By comparing the ratio of two different data analysis procedures, deviations from ideal plug flow can be detected. This method allows rapid measurement of flow character and does not interfere with the concurrent separation. We demonstrate easy detection of the onset of hydrodynamic flow induced by both gravity siphoning and an ionic strength buffer discontinuity. A brief analysis of the radially averaged peak shapes is also presented.
Large deviations for tandem queueing systems
Roland L. Dobrushin
1994-01-01
Full Text Available The crude asymptotics of the large delay probability in a tandem queueing system is considered. The main result states that one of the two channels in the tandem system defines the crude asymptotics. The constant that determines the crude asymptotics is given. The results obtained are based on the large deviation principle for random processes with independent increments on an infinite interval recently established by the authors.
Fonseca, Daniel; Cartaxo, Adolfo V. T.; Monteiro, Paulo P.
2007-06-01
The impact of the extinction ratio (ER) on the performance of a 40-Gb/s return-to-zero transmission system over standard single-mode fiber (SSMF) is presented. Several dispersion maps are analyzed in order to minimize the distortion due to the intrachannel nonlinear effects, namely, intrachannel cross-phase modulation and intrachannel four wave mixing (IFWM). The decrease of the ER until a specific value leads to an increase of the intensity distortion, which is mainly due to IFWM. As a consequence, two distinct transmission regimes are identified, depending on the input average power of each section and the ER of the optical signals. The first regime has previously been called the pseudolinear regime in the literature and occurs when high ERs are considered. The optimum dispersion map of this regime has a given optical precompensation and a total residual dispersion near zero. The second regime occurs with the decrease of the ER. Under such a circumstance, the optimum dispersion map obtained in the pseudolinear regime leads to significant degradation, which is mainly due to ghost pulses appearing in the symbol “0.” This effect can be reduced by a system with residual dispersion that is significantly different from zero, leading to a detected eye pattern with low degradation in the symbol “0” but high timing jitter, which limits the use of such signals in feasible transmission systems. We call this new regime pseudosolitonic as the intrachannel nonlinear effects are apparently reduced by the residual group velocity dispersion (as it is observed in the solitonic regime occurring at lower bit rates), but strong waveform degradation occurs along the SSMF transmission. The exact value of ER for which the change between the two transmission regimes is observed depends on the optical average power at the input of each section. A simple expression to predict the system conditions (namely, ER, input average power of each section, and number of sections) for which
On large deviations for ensembles of distributions
Khrychev, D A [Moscow State Institute of Radio-Engineering, Electronics and Automation (Technical University), Moscow (Russian Federation)
2013-11-30
The paper is concerned with the large deviations problem in the Freidlin-Wentzell formulation without the assumption of the uniqueness of the solution to the equation involving white noise. In other words, it is assumed that for each ε>0 the nonempty set P{sub ε} of weak solutions is not necessarily a singleton. Analogues of a number of concepts in the theory of large deviations are introduced for the set (P{sub ε}, ε>0), hereafter referred to as an ensemble of distributions. The ensembles of weak solutions of an n-dimensional stochastic Navier-Stokes system and stochastic wave equation with power-law nonlinearity are shown to be uniformly exponentially tight. An idempotent Wiener process in a Hilbert space and idempotent partial differential equations are defined. The accumulation points in the sense of large deviations of the ensembles in question are shown to be weak solutions of the corresponding idempotent equations. Bibliography: 14 titles.
Stochastic gene expression conditioned on large deviations
Horowitz, Jordan M.; Kulkarni, Rahul V.
2017-06-01
The intrinsic stochasticity of gene expression can give rise to large fluctuations and rare events that drive phenotypic variation in a population of genetically identical cells. Characterizing the fluctuations that give rise to such rare events motivates the analysis of large deviations in stochastic models of gene expression. Recent developments in non-equilibrium statistical mechanics have led to a framework for analyzing Markovian processes conditioned on rare events and for representing such processes by conditioning-free driven Markovian processes. We use this framework, in combination with approaches based on queueing theory, to analyze a general class of stochastic models of gene expression. Modeling gene expression as a Batch Markovian Arrival Process (BMAP), we derive exact analytical results quantifying large deviations of time-integrated random variables such as promoter activity fluctuations. We find that the conditioning-free driven process can also be represented by a BMAP that has the same form as the original process, but with renormalized parameters. The results obtained can be used to quantify the likelihood of large deviations, to characterize system fluctuations conditional on rare events and to identify combinations of model parameters that can give rise to dynamical phase transitions in system dynamics.
Analysis of Road Base Uniformity via the Deviation of Modulus of Asphalt Mixtures
ZHI Yufeng; ZHANG Xiaoning
2007-01-01
The modulus deviation of base material calculated from the data of falling weight deflectometer (FWD) was used to evaluate the uniformity of road base so as to reflect the construction quality. Four parameters,the repeatability standard deviation of the data in the same driveway, the reproducibility standard deviation of the data in the different driveway, the consistency statistics value of the data in the different driveway, and the consistency statistics value of the data in the same driveway, were introduced for the construction uniformity analysis. The experimental result shows that the materials modulus calculated from FWD has a highly correlative relationship with the uniformity of road base.
On the physical chemistry of seawater with deviating ion composition
Feistel, R. [Rostock Univ., Warnemuende (Germany). Inst. fuer Ostseeforschung
1998-04-01
The salt composition in natural seawaters is not strictly conservative. Physico-chemical properties of the mixed electrolyte ``standard seawater`` and their variations with ionic composition are briefly reviewed. It is shown that a ``same absolute salinity`` rule, known from seawater densities, may lead to good results for sound speeds, too. Refractive index measurements have now become sufficiently precise to detect local deviations of ion abundances along with routine ocean profiling. The question is discussed which quantities/formulas still need to be quantitatively determined for this purpose, and which theoretical, empirical or experimental aids can be applied. (orig.) 52 refs.
B. N. Patel, S. S. Jaiwar, N. A. Patel, V. R. Akbari and P. B. Dave
2014-12-01
Full Text Available A line x tester analysis was undertaken to estimates the magnitude of heterosis and dominance deviation in Gossypium hirsutum L. for yield, its components and other matricate characters in 60 test entries including (44 F1s along with 15 parents and 1 standard check hybrid. Analysis of variance indicated the significant difference among the parents and hybrids for all 12 characters studied which revealed existence of variability among the genotypes. Studies revealed that out of 44 cross combinations, only 3 hybrids viz., BC-68-2 x MCU 11, BC-68-2 x AC 738 and BN 1 x Reba-B-50 depicted significant and positive heterosis over standard check hybrid G. Cot. Hy. 12. The hybrid BC-68-2 x MCU 11 exhibited significant positive standard heterosis for seed cotton yield per plant and other attributing characters i.e. total number of bolls per plant, average boll weight, lint yield per plant and lint index. The mean values of potence ratio in all twelve characters suggested that degree of dominance was governed by over dominance genes for the expression of all the characters under study.
LARGE DEVIATIONS AND MODERATE DEVIATIONS FOR m-NEGATIVELY ASSOCIATED RANDOM VARIABLES
Hu Yijun; Ming Ruixing; Yang Wenquan
2007-01-01
M-negatively associated random variables, which generalizes the classical one of negatively associated random variables and includes m-dependent sequences as its particular case, are introduced and studied. Large deviation principles and moderate deviation upper bounds for stationary m-negatively associated random variables are proved.Kolmogorov-type and Marcinkiewicz-type strong laws of large numbers as well as the three series theorem for m-negatively associated random variables are also given.
Meiosis and its deviations in polyploid plants.
Grandont, L; Jenczewski, E; Lloyd, A
2013-01-01
Meiosis is a fundamental process in all sexual organisms that ensures fertility and genome stability and creates genetic diversity. For each of these outcomes, the exclusive formation of crossovers between homologous chromosomes is needed. This is more difficult to achieve in polyploid species which have more than 2 sets of chromosomes able to recombine. In this review, we describe how meiosis and meiotic recombination 'deviate' in polyploid plants compared to diploids, and give an overview of current knowledge on how they are regulated. See also the sister article focusing on animals by Stenberg and Saura in this themed issue.
Guessing Revisited: A Large Deviations Approach
Hanawal, Manjesh Kumar
2010-01-01
The problem of guessing a random string is revisited. A close relation between guessing and compression is first established. Then it is shown that if the sequence of distributions of the information spectrum satisfies the large deviation property with a certain rate function, then the limiting guessing exponent exists and is a scalar multiple of the Legendre-Fenchel dual of the rate function. Other sufficient conditions related to certain continuity properties of the information spectrum are briefly discussed. This approach highlights the importance of the information spectrum in determining the limiting guessing exponent. All known prior results are then re-derived as example applications of our unifying approach.
VAR Portfolio Optimal: Perbandingan Antara Metode Markowitz dan Mean Absolute Deviation
R. Agus Sartono
2009-05-01
Full Text Available Portfolio selection method which have been introduced by Harry Markowitz (1952 used variance or deviation standard as a measure of risk. Kanno and Yamazaki (1991 introduced another method and used mean absolute deviation as a measure of risk instead of variance. The Value-at Risk (VaR is a relatively new method to capitalized risk that been used by financial institutions. The aim of this research is compare between mean variance and mean absolute deviation of two portfolios. Next, we attempt to assess the VaR of two portfolios using delta normal method and historical simulation. We use the secondary data from the Jakarta Stock Exchange – LQ45 during 2003. We find that there is a weak-positive correlation between deviation standard and return in both portfolios. The VaR nolmal delta based on mean absolute deviation method eventually is higher than the VaR normal delta based on mean variance method. However, based on the historical simulation the VaR of two methods is statistically insignificant. Thus, the deviation standard is sufficient measures of portfolio risk.Keywords: optimalisasi portofolio, mean-variance, mean-absolute deviation, value-at-risk, metode delta normal, metode simulasi historis
Statistical properties of the deviations of f 0 F 2 from monthly medians
Y. Tulunay
2002-06-01
Full Text Available The deviations of hourly f 0 F 2 from monthly medians for 20 stations in Europe during the period 1958-1998 are studied. Spectral analysis is used to show that, both for original data (for each hour and for the deviations from monthly medians, the deterministic components are the harmonics of 11 years (solar cycle, 1 year and its harmonics, 27 days and 12 h 50.49 m (2nd harmonic of lunar rotation period L 2 periodicities. Using histograms for one year samples, it is shown that the deviations from monthly medians are nearly zero mean (mean < 0.5 and approximately Gaussian (relative difference range between %10 to %20 and their standard deviations are larger for daylight hours (in the range 5-7. It is shown that the amplitude distribution of the positive and negative deviations is nearly symmetrical at night hours, but asymmetrical for day hours. The positive and negative deviations are then studied separately and it is observed that the positive deviations are nearly independent of R12 except for high latitudes, but negative deviations are modulated by R12 . The 90% confidence interval for negative deviations for each station and each hour is computed as a linear model in terms of R12. After correction for local time, it is shown that for all hours the confidence intervals increase with latitude but decrease above 60N. Long-term trend analysis showed that there is an increase in the amplitude of positive deviations from monthly means irrespective of the solar conditions. Using spectral analysis it is also shown that the seasonal dependency of negative deviations is more accentuated than the seasonal dependency of positive deviations especially at low latitudes. In certain stations, it is also observed that the 4th harmonic of 1 year corresponding to a periodicity of 3 months, which is missing in f 0 F 2 data, appears in the spectra of negative variations.
Large-Deviation Results for Discriminant Statistics of Gaussian Locally Stationary Processes
Junichi Hirukawa
2012-01-01
Full Text Available This paper discusses the large-deviation principle of discriminant statistics for Gaussian locally stationary processes. First, large-deviation theorems for quadratic forms and the log-likelihood ratio for a Gaussian locally stationary process with a mean function are proved. Their asymptotics are described by the large deviation rate functions. Second, we consider the situations where processes are misspecified to be stationary. In these misspecified cases, we formally make the log-likelihood ratio discriminant statistics and derive the large deviation theorems of them. Since they are complicated, they are evaluated and illustrated by numerical examples. We realize the misspecification of the process to be stationary seriously affecting our discrimination.
Deviation from Power Law Behavior in Landslide Phenomenon
Li, L.; Lan, H.; Wu, Y.
2013-12-01
Power law distribution of magnitude is widely observed in many natural hazards (e.g., earthquake, floods, tornadoes, and forest fires). Landslide is unique as the size distribution of landslide is characterized by a power law decrease with a rollover in the small size end. Yet, the emergence of the rollover, i.e., the deviation from power law behavior for small size landslides, remains a mystery. In this contribution, we grouped the forces applied on landslide bodies into two categories: 1) the forces proportional to the volume of failure mass (gravity and friction), and 2) the forces proportional to the area of failure surface (cohesion). Failure occurs when the forces proportional to volume exceed the forces proportional to surface area. As such, given a certain mechanical configuration, the failure volume to failure surface area ratio must exceed a corresponding threshold to guarantee a failure. Assuming all landslides share a uniform shape, which means the volume to surface area ratio of landslide regularly increase with the landslide volume, a cutoff of landslide volume distribution in the small size end can be defined. However, in realistic landslide phenomena, where heterogeneities of landslide shape and mechanical configuration are existent, a simple cutoff of landslide volume distribution does not exist. The stochasticity of landslide shape introduce a probability distribution of the volume to surface area ratio with regard to landslide volume, with which the probability that the volume to surface ratio exceed the threshold can be estimated regarding values of landslide volume. An experiment based on empirical data showed that this probability can induce the power law distribution of landslide volume roll down in the small size end. We therefore proposed that the constraints on the failure volume to failure surface area ratio together with the heterogeneity of landslide geometry and mechanical configuration attribute for the deviation from power law
Theory of Deviation and Its Application in College English Teaching
Xu Yanqiu
2008-01-01
Deviation is an important concept in stylistics.Besides Shklovskij and Mukarovsky,who made a theoreti cal generalization of deviational phenomena,Leech is the one who studies deviation systematically and catego rizes it into groups.To apply the theory of deviation to College English teaching is an effective way to culti rate students' interest in and aesthetic ability of English texts.
Hypotropic Dissociated Vertical Deviation; a Case Report
Zhale Rajavi
2013-01-01
Full Text Available Purpose: To report the clinical features of a rare case of hypotropic dissociated vertical deviation (DVD. Case report: A 25-year-old female was referred with unilateral esotropia, hypotropia and slow variable downward drift in her left eye. She had history of esotropia since she had been 3-4 months of age. Best corrected visual acuity was 20/20 in her right eye and 20/40 in the left one when hyperopia was corrected. She underwent bimedial rectus muscle recession of 5.25mm for 45 prism diopters (PDs of esotropia. She was orthophoric 3 months after surgery and no further operation was planned for correction of the hypotropic DVD. Conclusion: This rare case of hypotropic DVD showed only mild amblyopia in her non-fixating eye. The etiology was most probably acquired considering hyperopia as a sign of early onset accommodative esotropia.
Spotting deviations from R^2 inflation
de la Cruz-Dombriz, Alvaro; Odintsov, Sergei D; Saez-Gomez, Diego
2016-01-01
We discuss the soundness of inflationary scenarios in theories beyond the Starobinsky model, namely a class of theories described by arbitrary functions of the Ricci scalar and the K-essence field. We discuss the pathologies associated with higher-order equations of motion which will be shown to constrain the stability of this class of theories. We provide a general framework to calculate the slow-roll parameters and the corresponding mappings to the theory parameters. For paradigmatic gravitational models within the class of theories under consideration we illustrate the power of the Planck/Bicep2 latest results to constrain such gravitational Lagrangians. Finally, bounds for potential deviations from Starobinsky-like inflation are derived.
Large Deviations and Asymptotic Methods in Finance
Gatheral, Jim; Gulisashvili, Archil; Jacquier, Antoine; Teichmann, Josef
2015-01-01
Topics covered in this volume (large deviations, differential geometry, asymptotic expansions, central limit theorems) give a full picture of the current advances in the application of asymptotic methods in mathematical finance, and thereby provide rigorous solutions to important mathematical and financial issues, such as implied volatility asymptotics, local volatility extrapolation, systemic risk and volatility estimation. This volume gathers together ground-breaking results in this field by some of its leading experts. Over the past decade, asymptotic methods have played an increasingly important role in the study of the behaviour of (financial) models. These methods provide a useful alternative to numerical methods in settings where the latter may lose accuracy (in extremes such as small and large strikes, and small maturities), and lead to a clearer understanding of the behaviour of models, and of the influence of parameters on this behaviour. Graduate students, researchers and practitioners will find th...
An discussion on Graphological Deviation in Oliver Twist
肖潇
2016-01-01
In stylistic analysis,when we identifying the stylistic features in literary works,deviation serves as an important sign.According to Leech,there are eight types of deviation in poetry:lexical deviation,grammatical deviation,phonological deviation,graphological deviation,semantic deviation,dialectal deviation,deviation of register,deviation of historical period. Realism marks as an significant development in the history of fiction,for its success in achieving an exposure of the truth of people’s real life and fierce social problems.And foregrounded feature is inevitable part that constitute his language style.We will focus on Oliver Twist,for it is presented with unique writing style,which worthy our investigation.
Severo, Milton; Silva-Pereira, Fernanda; Ferreira, Maria Amelia
2013-01-01
Several studies have shown that the standard error of measurement (SEM) can be used as an additional “safety net” to reduce the frequency of false-positive or false-negative student grading classifications. Practical examinations in clinical anatomy are often used as diagnostic tests to admit students to course final examinations. The aim of this…
2015-01-01
Purpose In high-dose-rate (HDR) brachytherapy (BT), the source dwell times and dwell positions are essential treatment planning parameters. An optimal choice of these factors is fundamental to obtain the desired target coverage with the lowest achievable dose to the organs at risk (OARs). This study evaluates relevant dose parameters in cervix brachytherapy in order to assess existing tandem-ring dwell time ratio used at the first HDR BT center in Nigeria, and compare it with an alternative s...
Raju, M
2011-11-01
Full Text Available and optimization of core sampling procedure for carbon isotope analysis in eucalyptus and variation in carbon isotope ratios across species and growth conditions Mohan Raju, B#; Nuveshen Naidoo*; Sheshshaayee, M. S; Verryn, S. D*; Kamalkannan, R^; Bindumadhava... isotope analysis in Eucalyptus. Methods Expt 1: * Cores were taken from periphery to pith in 5 year old trees of Eucalyptus * Five half sib families of Eucalyptus grandis & E. urophylla were used ? Cores were further subdivided into 5 fragments...
Large Deviations for Random Matricial Moment Problems
Nagel, Jan; Gamboa, Fabrice; Rouault, Alain
2010-01-01
We consider the moment space $\\mathcal{M}_n^{K}$ corresponding to $p \\times p$ complex matrix measures defined on $K$ ($K=[0,1]$ or $K=\\D$). We endow this set with the uniform law. We are mainly interested in large deviations principles (LDP) when $n \\rightarrow \\infty$. First we fix an integer $k$ and study the vector of the first $k$ components of a random element of $\\mathcal{M}_n^{K}$. We obtain a LDP in the set of $k$-arrays of $p\\times p$ matrices. Then we lift a random element of $\\mathcal{M}_n^{K}$ into a random measure and prove a LDP at the level of random measures. We end with a LDP on Carth\\'eodory and Schur random functions. These last functions are well connected to the above random measure. In all these problems, we take advantage of the so-called canonical moments technique by introducing new (matricial) random variables that are independent and have explicit distributions.
Meiosis and its deviations in polyploid animals.
Stenberg, P; Saura, A
2013-01-01
We review the different modes of meiosis and its deviations encountered in polyploid animals. Bisexual reproduction involving normal meiosis occurs in some allopolyploid frogs with variable degrees of polyploidy. Aberrant modes of bisexual reproduction include gynogenesis, where a sperm stimulates the egg to develop. The sperm may enter the egg but there is no fertilization and syngamy. In hybridogenesis, a genome is eliminated to produce haploid or diploid eggs or sperm. Ploidy can be elevated by fertilization with a haploid sperm in meiotic hybridogenesis, which elevates the ploidy of hybrid offspring such that they produce diploid gametes. Polyploids are then produced in the next generation. In kleptogenesis, females acquire full or partial genomes from their partners. In pre-equalizing hybrid meiosis, one genome is transmitted in the Mendelian fashion, while the other is transmitted clonally. Parthenogenetic animals have a very wide range of mechanisms for restoring or maintaining the mother's ploidy level, including gamete duplication, terminal fusion, central fusion, fusion of the first polar nucleus with the product of the first division, and premeiotic duplication followed by a normal meiosis. In apomictic parthenogenesis, meiosis is replaced by what is effectively mitotic cell division. The above modes have different evolutionary consequences, which are discussed. See also the sister article by Grandont et al. in this themed issue.
Large deviations in the random sieve
Grimmett, Geoffrey
1997-05-01
The proportion [rho]k of gaps with length k between square-free numbers is shown to satisfy log[rho]k=[minus sign](1+o(1))(6/[pi]2) klogk as k[rightward arrow][infty infinity]. Such asymptotics are consistent with Erdos's challenge to prove that the gap following the square-free number t is smaller than clogt/log logt, for all t and some constant c satisfying c>[pi]2/12. The results of this paper are achieved by studying the probabilities of large deviations in a certain ‘random sieve’, for which the proportions [rho]k have representations as probabilities. The asymptotic form of [rho]k may be obtained in situations of greater generality, when the squared primes are replaced by an arbitrary sequence (sr) of relatively prime integers satisfying [sum L: summation operator]r1/sr<[infty infinity], subject to two further conditions of regularity on this sequence.
Bednyakov, V A; Kovalenko, S G
1994-01-01
The top quark mass values from the CDF Collaboration and the precision electroweak data at LEP combined with the bottom mass value allow to establish bounds on the parameter tan beta in the minimal supersymmetric standard model (MSSM) independent of the soft supersymmetry breaking parameters. We find: 0.96 1, where radiative electroweak symmetry breaking is possible. Assuming electroweak symmetry breaking leads to: tan beta=1.2 +- 0.2, if one neglects the high tan beta solution, which is unlikely due to proton lifetime limits.
A Historical Study of Contemporary Human Rights: Deviation or Extinction?
Tanel Kerikmäe
2016-10-01
Full Text Available Human rights is a core issue of continuing political, legal and economic relevance. The current article discusses the historical perceptions of the very essence of human rights standards and poses the question whether the Realpolitik of the changed world and Europe can justify the deviation from the “purist” approach to human rights. The EU Charter, as the most eminent and contemporary “bill of rights”, is chosen as an example of the divergence from “traditional values”. The article does not offer solutions but rather focuses on the expansive development in the doctrinal approach of interpreting human rights that has not been conceptually agreed upon by historians, philosophers and legal scholars.
Deviation Optimal Learning using Greedy Q-aggregation
Dai, Dong; Zhang, Tong
2012-01-01
Given a finite family of functions, the goal of model selection is to construct a procedure that mimics the function from this family that is the closest to an unknown regression function. More precisely, we consider a general regression model with fixed design and measure the distance between functions by the mean squared error at the design points. While procedures based on exponential weights are known to solve the problem of model selection in expectation, they are, surprisingly, sub-optimal in deviation. We propose a new formulation called Q-aggregation that addresses this limitation; namely, its solution leads to sharp oracle inequalities that are optimal in a minimax sense. Moreover, based on the new formulation, we design greedy Q-aggregation procedures that produce sparse aggregation models achieving the optimal rate. The convergence and performance of these greedy procedures are illustrated and compared with other standard methods on simulated examples.
Large deviations of the maximal eigenvalue of random matrices
Borot, Gaëtan; Majumdar, Satya; Nadal, Céline
2011-01-01
We present detailed computations of the 'at least finite' terms (three dominant orders) of the free energy in a one-cut matrix model with a hard edge a, in beta-ensembles, with any polynomial potential. beta is a positive number, so not restricted to the standard values beta = 1 (hermitian matrices), beta = 1/2 (symmetric matrices), beta = 2 (quaternionic self-dual matrices). This model allows to study the statistic of the maximum eigenvalue of random matrices. We compute the large deviation function to the left of the expected maximum. We specialize our results to the gaussian beta-ensembles and check them numerically. Our method is based on general results and procedures already developed in the literature to solve the Pastur equations (also called "loop equations"). It allows to compute the left tail of the analog of Tracy-Widom laws for any beta, including the constant term.
Aguocha Chinyere M
2009-09-01
Full Text Available Abstract Background There may be need to assess intelligent quotient (IQ scores in sub-Saharan African children with intellectual disability, either for the purpose of educational needs assessment or research. However, modern intelligence scales developed in the western parts of the world suffer limitation of widespread use because of the influence of socio-cultural variations across the world. This study examined the agreement between IQ scores estimation among Nigerian children with intellectual disability using clinicians' judgment based on International Classification of Diseases, tenth Edition (ICD - 10 criteria for mental retardation and caregivers judgment based on 'ratio IQ' scores calculated from estimated mental age in the context of socio-cultural milieu of the children. It proposed a viable option of IQ score assessment among sub-Saharan African children with intellectual disability, using a ratio of culture-specific estimated mental age and chronological age of the child in the absence of standardized alternatives, borne out of great diversity in socio-cultural context of sub-Saharan Africa. Methods Clinicians and care-givers independently assessed the children in relation to their socio-cultural background. Clinicians assessed the IQ scores of the children based on the ICD - 10 diagnostic criteria for mental retardation. 'Ratio IQ' scores were calculated from the ratio of estimated mental age and chronological age of each child. The IQ scores as assessed by the clinicians were then compared with the 'ratio IQ' scores using correlation statistics. Results A total of forty-four (44 children with intellectual disability were assessed. There was a significant correlation between clinicians' assessed IQ scores and the 'ratio IQ' scores employing zero order correlation without controlling for the chronological age of the children (r = 0.47, df = 42, p = 0.001. First order correlation controlling for the chronological age of the children
Assessment of gait deviation on the Babinski-Weill test in healthy Brazilians
Camila Souza Miranda
2013-09-01
Full Text Available Objective The aim of this study was to validate a simple and reproducible method for assessing gait deviation on the Babinski-Weill test in a representative sample of healthy Brazilians. Methods Gait deviations were measured in 75 individuals (median=30 years, 41 women for forward, backwards, and Babinski-Weill steps. The test entailed blindfolded individuals walking 10 paces at a frequency of 1 Hz with deviations subsequently measured by a protractor. Results Mean gait deviation forward was 0.53° with standard deviation (SD=4.22 and backwards was 2.14° with SD=4.29. No significant difference in deviation was detected between genders (t test p=0.40 forward and p=0.77 backwards or for age (ANOVA, p=0.33 forward and p=0.63 backwards. On the Babinski-Weill test, mean gait deviation was 5.26°; SD=16.32 in women and -3.11°; SD=12.41 in men, with no significant difference between genders (t test, p=0.056. Discussion Defining normative gait patterns helps distinguish pathological states.
9 CFR 318.308 - Deviations in processing.
2010-01-01
... AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY...) Deviations in processing (or process deviations) must be handled according to: (1)(i) A HACCP plan for canned...) of this section. (c) (d) Procedures for handling process deviations where the HACCP plan...
21 CFR 330.11 - NDA deviations from applicable monograph.
2010-04-01
... 21 Food and Drugs 5 2010-04-01 2010-04-01 false NDA deviations from applicable monograph. 330.11... EFFECTIVE AND NOT MISBRANDED Administrative Procedures § 330.11 NDA deviations from applicable monograph. A new drug application requesting approval of an OTC drug deviating in any respect from a monograph that...
Large deviations for Glauber dynamics of continuous gas
2008-01-01
This paper is devoted to the large deviation principles of the Glauber-type dynamics of finite or infinite volume continuous particle systems.We prove that the level-2 empirical process satisfies the large deviation principles in the weak convergence topology,while it does not satisfy the large deviation principles in the T-topology.
Hermínio J. Rocha-Neto
2015-10-01
Full Text Available Abstract: The VHS and CTR were assessed using computerized thoracic radiographs of ten clinically healthy tufted capuchin monkeys (five males and five females from the Wild Animal Screening Center in São Luís (Centro de Triagem de Animais Silvestres de São Luís-MA-CETAS. Radiographs were taken in laterolateral and dorsoventral projections to calculate the cardiothoracic ratio (VHS and vertebral heart size (CTR. The VHS showed mean values of 9.34±0.32v (males and 9.16±0.34v (females and there was no statistical difference between males and females (p>0.05. The CTR showed mean values of 0.55±0.04 (males and 0.52±0.03 (females and there was no statistical difference between the sexes (p>0.05. There was positive correlation between VHS and CTR (r=0.78. The thoracic and heart diameters showed mean values of 5.70±0.48cm and 2.16±0.40cm in the males, respectively. In the females they measured 5.32±0.39cm and 2.94±0.32cm. There was no statistical difference between the sexes. Our results show that the high correlation found between VHS and CTR permitted the verification with similar clinical precision between the two methods to estimate alterations in the heart silhouette by radiographic examination of tufted capuchin, making it an easy technique to apply that can be considered in the investigation of heart problems for this wild species.
Barea, R; Brossard, L; Le Floc'h, N; Primot, Y; van Milgen, J
2009-12-01
Most studies concerning the Ile requirement in pigs have been carried out using blood products as a protein source, and these have a relatively low Ile content relative to the other branched-chain AA (BCAA). There are indications that an excess supply of one BCAA can affect the utilization of the other BCAA. Little information is available concerning the Ile requirement in pigs when the supply of the other BCAA is moderate (e.g., in cereal- and soybean meal-based diets). The objective of the present study was to evaluate the response of piglets to Ile supplementation under different nutritional conditions. In all experiments, piglets were housed individually and had ad libitum access to feed during a 3-wk period. The first experiment was carried out to study the response of piglets to an increasing Ile supply by using 2 sources of l-Ile differing in degree of purity. Piglets received either a control diet with 48% standardized ileal digestible (SID) Ile:Lys or 1 of 4 other diets containing graded levels of either source of l-Ile to provide 52 or 56% SID Ile:Lys. All diets were formulated to provide 1.00% SID Lys in the diet. Feed intake and growth were not affected by Ile level or Ile source. Experiment 2 was performed to exclude a possible interaction between Ile and Lys supply. In a 2 x 2 factorial arrangement, 2 levels of Lys (1.00 and 1.15% SID Lys) and 2 levels of Ile (48 and 60% SID Ile:Lys) were used. Growth and G:F were 8 and 7% greater in piglets receiving the diet with the greater Lys content, but the Ile:Lys did not affect performance. No interactions were observed between the Lys and Ile supplies. In Exp. 3, a 2 x 2 factorial arrangement was used to test the effect of protein source (spray-dried blood cells or corn gluten meal) and Ile supply (50 or 65% SID Ile:Lys) on performance in piglets. Both protein sources had an elevated BCAA content but differed in Leu and Val contents. Protein source or Ile supply did not affect feed intake, growth, or G:F in
官玲俊; 谢泽渊; 江向阳
2013-01-01
Based on the national the currently executing public building energy efficiency standards , analysis and evaluation of the current energy -saving standard for central air conditioning system comprehensive Energy Efficiency ratio applicable scope , through the two practical engineering projects , evaluate comprehensive Energy Efficiency ra-tio of the temperature humidity independent control air conditioning system.Through the calculation analysis , this paper concludes that the current national standards for public buildings central air conditioning system minimum EER constraint value is 2.67 W/W, In this paper is beneficial for evaluation EER of new buildings air conditioning sys -tem and existing building air conditioning system energy saving operation provides a reliable technical data support .%基于国家当前执行的公共建筑节能标准，评价分析了当前节能标准对于中央空调系统综合能效比适用范围，通过计算分析得出：现行国家标准对于公共建筑中央空调系统最低能效比约束值为2.67 W/W，本文对于评价新建筑建筑空调系统能效比和既有建筑空调系统节能运营提供了可靠的技术数据支撑。
R. Hajian
2012-01-01
Full Text Available A new spectrophotometric method was developed for the simultaneous analysis of a ternary mixture containing paracetamol (PAR, ibuprofen (IBU and caffeine (CAF without prior separation. H-point standard addition method (HPSAM was used for the first time in the analysis of a component (IBU in a ternary mixture (paracetamol, ibuprofen and caffeine. In contrast, PAR and CAF determined using double divisor ratio spectra derivative method. This method is based on the use of derivative of the ratio spectrum obtained by dividing the absorption spectrum of the ternary mixture by a standard spectrum of a mixture of two of the three compounds in the title mixture. The concentrations of PAR and CAF compounds in their mixture are determined by using their respective standard addition graphs which are obtained by measuring the amplitude at either the maximum or minimum wavelengths selected. The mathematical explanation of the procedure is illustrated. It was shown that at wavelengths 226 and 260 nm, the coordinate of H-point is only dependent on the concentration of IBU without any interference by PAR and CAF. This method was successfully applied for the analysis of Novafen capsule, with no interference from excipients as indicated by the recovery study results. The proposed method is simple and rapid and can be easily used in the quality control of drugs as an alternative analysis tools.
Temperature deviation index and elderly mortality in Japan
Lim, Youn-Hee; Reid, Colleen E.; Honda, Yasushi; Kim, Ho
2016-07-01
Few studies have examined how the precedence of abnormal temperatures in previous neighboring years affects the population's health. In the present study, we attempted to quantify the health effects of abnormal weather patterns by creating a metric called the temperature deviation index (TDI) and estimated the effects of TDI on mortality in Japan. We used data from 47 prefectures in Japan to compute the TDI on days between May and September from 1966 to 2010. The TDI is a summed product of an indicator of absence of high temperatures in the neighboring years, and more weights were assigned to the years closest to the current year. To estimate the TDI effects on elderly mortality, we used generalized linear modeling with a Poisson distribution after adjusting for apparent temperature, barometric pressure, day of the week, and time trend. For each prefecture, we estimated the TDI effects and pooled the estimates to yield a national average for 1991-2010 in Japan. The estimated effects of TDI in middle- or high-latitude prefectures were greater than in low-latitude prefectures. The estimated national average of TDI effects was a 0.5 % (95 % confidence intervals [CI], 0.1, 1.0) increase in elderly mortality per 1-unit (around 1 standard deviation) increase in the TDI. The significant pooled estimation of TDI effects was mainly due to the TDI effects on summer days with moderate temperature (25th-49th percentile, mean temperature 22.9 °C): a 1.9 % (95 % CI, 1.1, 2.6) increase in elderly mortality per 1-unit increase in the TDI. However, TDI effects were insignificant in other temperature ranges. These findings suggest that elderly deaths increased on moderate temperature days in the summer that differed substantially from days during that time window in the neighboring years. Therefore, not only high temperature itself but also temperature deviation compared to previous years could be considered to be a risk factor for elderly mortality in the summer.
49 CFR 192.943 - When can an operator deviate from these reassessment intervals?
2010-10-01
...) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Gas... 49 Transportation 3 2010-10-01 2010-10-01 false When can an operator deviate from these reassessment intervals? 192.943 Section 192.943 Transportation Other Regulations Relating to Transportation...
无
2010-01-01
In this paper, we study an even order neutral differential equation with deviating arguments, and obtain new oscillation results without the assumptions which were required for related results given before. Our results extend and improve many known oscillation criteria, based on the standard integral averaging technique.
Mechanism Modeling and Simulation Based on Dimensional Deviation
无
2008-01-01
To analyze the effects on motion characteristics of mechanisms of dimensional variations, a study on random dimensional deviation generation techniques for 3D models on the basis of the present mechanical modeling software was carried out, which utilized the redeveloped interfaces provided by the modeling software to develop a random dimensional deviation generation system with certain probability distribution characteristics. This system has been used to perform modeling and simulation of the specific mechanical time delayed mechanism under multiple deviation varieties, simulation results indicate the dynamic characteristics of the mechanism are influenced significantly by the dimensional deviation in the tolerance distribution range, which should be emphasized in the design.
Deviation and rotation of the larynx in computer tomography
Shibusawa, Mitsunobu (Tokyo Medical and Dental Univ., Tokyo (Japan). Medical Research Institute); Yano, Kazuhiko
1990-01-01
Many authors described the clinical importance of asymmetry of the laryngeal framework. However, its pathogenesis is generally unknown. In this study, CT images of 315 Japanese subjects were investigated to define the laryngeal position relative to the midline of the cervical vertebra. The CT slice of each subject within 5 mm cephalad of the cricoarytenoid joint was traced. Then, the deviation and rotation angles were measured using our method. Seventy one percent of the subjects' larynges deviated and/or rotated to the right side, while 17% to the left side. Six percent showed neither deviation nor rotation. As to the rest of 6%, deviation and rotation were in opposite directions. Besides, the length of the thyroid alae were measured in 282 subjects. Left ala was longer in 55%, and right was in 23%, and almost equal in 22%. The conclusions are as follows. The majority of the subjects' CT images showed deviation and/or rotation of the laryngeal framework to the right side. So called idiopathic laryngeal deviation is a case which observed in those cases with remarkable deviation and/or rotation of the laryngeal framework. Aging seemed to be an important factor in accerelation of the laryngeal deviation and rotation. The type of diseases and the side of mass lesions had no statistical significance in deviation and rotation of the larynx. (author).
The Horwitz ratio (HorRat): A useful index of method performance with respect to precision.
Horwitz, William; Albert, Richard
2006-01-01
The Horwitz ratio (HorRat) is a normalized performance parameter indicating the acceptability of methods of analysis with respect to among-laboratory precision (reproducibility). It is the ratio of the observed relative standard deviation among laboratories calculated from the actual performance data, RSDR (%), to the corresponding predicted relative standard deviation calculated from the Horwitz equation PRSDR (%) = 2C(-0.15), where C is the concentration found or added, expressed as a mass fraction. It is more or less independent of analyte, matrix, method, and time of publication (as a surrogate for the state of the art of analytical chemistry). It is now one of the acceptability criteria for many of the recently adopted chemical methods of analysis of AOAC INTERNATIONAL, the European Union, and other European organizations dealing with food analysis (e.g., European Committee for Standardization and Nordic Analytical Committee). The origin and applications of the formula are described. Consistent deviations from the ratio on the low side (values 2) may indicate inhomogeneity of the test samples, need for further method optimization or training, operating below the limit of determination, or an unsatisfactory method.
Honguero Martínez, A F; García Jiménez, M D; García Vicente, A; López-Torres Hidalgo, J; Colon, M J; van Gómez López, O; Soriano Castrejón, Á M; León Atance, P
2016-01-01
F-18 fluorodeoxyglucose integrated PET-CT scan is commonly used in the work-up of lung cancer to improve preoperative disease stage. The aim of the study was to analyze the ratio between SUVmax of N1 lymph nodes and primary lung cancer to establish prediction of mediastinal disease (N2) in patients operated on non-small cell lung cancer. This is a retrospective study of a prospective database. Patients operated on non-small cell lung cancer (NSCLC) with N1 disease by PET-CT scan were included. None of them had previous induction treatment, but they underwent standard surgical resection plus systematic lymphadenectomy. There were 51 patients with FDG-PET-CT scan N1 disease. 44 (86.3%) patients were male with a mean age of 64.1±10.8 years. Type of resection: pneumonectomy=4 (7.9%), lobectomy/bilobectomy=44 (86.2%), segmentectomy=3 (5.9%). adenocarcinoma=26 (51.0%), squamous=23 (45.1%), adenosquamous=2 (3.9%). Lymph nodes after surgical resection: N0=21 (41.2%), N1=12 (23.5%), N2=18 (35.3%). Mean ratio of the SUVmax of N1 lymph node to the SUVmax of the primary lung tumor (SUVmax N1/T ratio) was 0.60 (range 0.08-2.80). ROC curve analysis to obtain the optimal cut-off value of SUVmax N1/T ratio to predict N2 disease was performed. At multivariate analysis, we found that a ratio of 0.46 or greater was an independent predictor factor of N2 mediastinal lymph node metastases with a sensitivity and specificity of 77.8% and 69.7%, respectively. SUVmax N1/T ratio in NSCLC patients correlates with mediastinal lymph node metastasis (N2 disease) after surgical resection. When SUVmax N1/T ratio on integrated PET-CT scan is equal or superior to 0.46, special attention should be paid on higher probability of N2 disease. Copyright © 2015 Elsevier España, S.L.U. and SEMNIM. All rights reserved.
Naito T
2015-11-01
Full Text Available Tomoko Naito,1 Keiji Yoshikawa,2 Shiro Mizoue,3 Mami Nanno,4 Tairo Kimura,5 Hirotaka Suzumura,6 Ryuji Takeda,7 Fumio Shiraga1 1Department of Ophthalmology, Okayama University Graduate School of Medicine, Okayama, 2Yoshikawa Eye Clinic, Tokyo, 3Department of Ophthalmology, Ehime University Graduate School of Medicine, Ehime, 4Kagurazaka Minamino Eye Clinic, 5Ueno Eye Clinic, 6Suzumura Eye Clinic, Tokyo, 7Department of Agriculture, Kinki University, Nara, Japan Purpose: To analyze the relationship between consecutive deterioration of mean deviation (MD value and glaucomatous visual field (VF progression in open-angle glaucoma (OAG, including primary OAG and normal tension glaucoma.Patients and methods: The subjects of the study were patients undergoing treatment for OAG who had performed VF tests at least 10 times with a Humphrey field analyzer (SITA standard, C30-2 program. The VF progression was defined by a significantly negative MD slope (MD slope worsening at the final VF test during the follow-up period. The relationship between the MD slope worsening and the consecutive deterioration of MD value were retrospectively analyzed.Results: A total of 165 eyes of 165 patients were included in the analysis. Significant progression of VF defects was observed in 72 eyes of 72 patients (43.6%, while no significant progression was evident in 93 eyes of 93 patients (56.4%. There was significant relationship between the frequency of consecutive deterioration of MD value and MD slope worsening (P<0.0001, Cochran–Armitage trend test. A significant association was observed for MD slope worsening in the eyes with three (odds ratio: 2.1, P=0.0224 and four (odds ratio: 3.6, P=0.0008 consecutive deterioration of MD value in multiple logistic regression analysis, but no significant association in the eyes with two consecutive deterioration (odds ratio: 1.1, P=0.8282. The eyes with VF progression had significantly lower intraocular pressure reduction rate (P<0
Ramalingam, S; Jayaprakash, A; Mohan, S; Karabacak, M
2011-11-01
FT-IR and FT-Raman (4000-100 cm(-1)) spectral measurements of 3-methyl-1,2-butadiene (3M12B) have been attempted in the present work. Ab-initio HF and DFT (LSDA/B3LYP/B3PW91) calculations have been performed giving energies, optimized structures, harmonic vibrational frequencies, IR intensities and Raman activities. Complete vibrational assignments on the observed spectra are made with vibrational frequencies obtained by HF and DFT (LSDA/B3LYP/B3PW91) at 6-31G(d,p) and 6-311G(d,p) basis sets. The results of the calculations have been used to simulate IR and Raman spectra for the molecule that showed good agreement with the observed spectra. The potential energy distribution (PED) corresponding to each of the observed frequencies are calculated which confirms the reliability and precision of the assignment and analysis of the vibrational fundamentals modes. The oscillation of vibrational frequencies of butadiene due to the couple of methyl group is also discussed. A study on the electronic properties such as HOMO and LUMO energies, were performed by time-dependent DFT (TD-DFT) approach. The calculated HOMO and LUMO energies show that charge transfer occurs within the molecule. The thermodynamic properties of the title compound at different temperatures reveal the correlations between standard heat capacities (C) standard entropies (S), and standard enthalpy changes (H).
Refraction in Terms of the Deviation of the Light.
Goldberg, Fred M.
1985-01-01
Discusses refraction in terms of the deviation of light. Points out that in physics courses where very little mathematics is used, it might be more suitable to describe refraction entirely in terms of the deviation, rather than by introducing Snell's law. (DH)
Downhole control of deviation with steerable straight-hole turbodrills
Gaynor, T.M.
1988-03-01
Advances in directional drilling have until recently been confined to issues that are peripheral to the central problem of controlling assembly behavior downhole. Examples of these advances are measurement while drilling (MWD) and the increasing use of computer assistance in well planning. These were significant steps forward, but the major problem remained. Changes in formation deviation tendencies led to trips to change bottomhole assemblies (BHA's) to cope with the new conditions. There is almost no direct control of deviation behavior. The steerable straight-hole turbodrill (SST) addresses this problem directly, allowing alteration of the well course without the need to trip. The availability of such a system radically changes the way in which directional well planning may be approached. This paper describes the equipment used and the equipment's construction and operational requirements. It discusses the capabilities and current limitation of the systems. Field results are presented for some 300,000 ft (91 500 m) of deviated drilling carried out over 2 years in Alaska and the North Sea. A series of four highly deviated wells totaling 35,000 ft (10 700m) with only three deviation trips is included. The SST is the first deviation drilling system to achieve deviation control over long sections without tripping to change BHA's. Bits and downhole equipment are now more reliable and long-lived than ever, therefore, deviation trips are becoming a major target for well cost saving.
7 CFR 3015.3 - Conflicting policies and deviations.
2010-01-01
... 7 Agriculture 15 2010-01-01 2010-01-01 false Conflicting policies and deviations. 3015.3 Section... Conflicting policies and deviations. (a) Statutory provisions. Federal statutes that apply to some USDA grant..., when permissible under existing laws. In those instances where a program receives an exception to...
Large Deviations without Principle: Join the Shortest Queue
Ridder, Ad; Shwartz, Adam
2004-01-01
We develop a methodology for studying "large deviations type" questions. Our approach does not require that the large deviations principle holds, and is thus applicable to a larg class of systems. We study a system of queues with exponential servers, which share an arrival stream. Arrivals are route
38 CFR 36.4304 - Deviations; changes of identity.
2010-07-01
... identity. 36.4304 Section 36.4304 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... Deviations; changes of identity. A deviation of more than 5 percent between the estimates upon which a... change in the identity of the property upon which the original appraisal was based, will invalidate...
Large deviations for stochastic flows and their applications
高付清; 任佳刚
2001-01-01
Large deviations for stochastic flow solutions to SDEs containing a small parameter are studied. The obtained results are applied to establish a Cp, r-large deviation principle for stochastic flows and for solutions to anticipating SDEs. The recent results of Millet-Nualart-Sans and Yoshida are improved and refined.
Large Deviations and a Fluctuation Symmetry for Chaotic Homeomorphisms
Maes, Christian; Verbitskiy, Evgeny
2003-01-01
We consider expansive homeomorphisms with the specification property. We give a new simple proof of a large deviation principle for Gibbs measures corresponding to a regular potential and we establish a general symmetry of the rate function for the large deviations of the antisymmetric part, under t
[The crooked nose: correction of dorsal and caudal septal deviations].
Foda, H M T
2010-09-01
The deviated nose represents a complex cosmetic and functional problem. Septal surgery plays a central role in the successful management of the externally deviated nose. This study included 800 patients seeking rhinoplasty to correct external nasal deviations; 71% of these suffered from variable degrees of nasal obstruction. Septal surgery was necessary in 736 (92%) patients, not only to improve breathing, but also to achieve a straight, symmetric external nose. A graduated surgical approach was adopted to allow correction of the dorsal and caudal deviations of the nasal septum without weakening its structural support to the nasal dorsum or nasal tip. The approach depended on full mobilization of deviated cartilage, followed by straightening of the cartilage and its fixation in the corrected position by using bony splinting grafts through an external rhinoplasty approach.
Measurement of z-axis deviation angle of electro-optic crystal by conoscopic interference
Li, Dong; Liu, Yong; Liu, Xu; Jiang, Hongzhen; Zheng, Fanglan
2016-09-01
Properties of plasma electrode pockels cell is directly affected by the Z-axis deviation angle of the electro-optic crystal. Therefore, high precision measurement of the Z-axis deviation angle is indispensable. By using conoscopic interference technique, a measurement system for Z-axis deviation angle of electro-optic crystal is introduced. The principle of conoscopic interference method is described in detail, and a series of techniques are implied in this measurement system to improve the accuracy. High-precision positioning method of the crystal based on Michelson interference is proposed to determine the normal consistency of crystal, which can ensure the high positioning repeatability of crystal in the measurement process. The positioning comparison experiment of the crystal shows that the standard deviation of our method is less than 1pixel, which is much better than the traditional method (nearly 4pixels). Moreover, melatope extraction algorithm of optical axis based on image matching technique is proposed to ensure the melatope can be extracted in high precision. Calibration method of the normal of transmission surface of crystal is also proposed. The experiment results show that the PV and rms of Z-axis deviation angle is less than 0.05mrad and 0.02mrad, respectively. The repeatability accuracy is less than 0.01mrad.
Vertical deviations of the midplane of the Galaxy.
Malhotra, S.; Rhoads, J. E.
Besides the integral sign warp in the outer Galaxy, the gas in the Milky Way shows small, but systematic deviations from a flat z = 0 plane both in the inner and the outer Galaxy. In the inner Galaxy, the tangent points have no distance ambiguity, so their distances, and hence midplane deviations, can be measured. From the tangent point analysis the authors find that the molecular and atomic gas layers deviate from the z = 0 plane with an amplitude of ≅50 pc. Whether these deviations are due to a small, smooth inner warp or are similar to the m = 10 mode corrugations found in the outer Galaxy (Kulkarni, Blitz & Heiles, 1982) can be checked by looking at the two-dimensional (in Galactic radius and azimuthal angle) structure of the z deviations. For the inner Galaxy, distance ambiguity at points other than the tangent points makes the interpretation difficult, but these hypotheses can be checked in a limited way. Magnetic instabilities can cause vertical deviations of the gas, but if stars share the same deviations the origin has to be gravitational.
Structure of deviations from optimality in biological systems.
Pérez-Escudero, Alfonso; Rivera-Alba, Marta; de Polavieja, Gonzalo G
2009-12-01
Optimization theory has been used to analyze evolutionary adaptation. This theory has explained many features of biological systems, from the genetic code to animal behavior. However, these systems show important deviations from optimality. Typically, these deviations are large in some particular components of the system, whereas others seem to be almost optimal. Deviations from optimality may be due to many factors in evolution, including stochastic effects and finite time, that may not allow the system to reach the ideal optimum. However, we still expect the system to have a higher probability of reaching a state with a higher value of the proposed indirect measure of fitness. In systems of many components, this implies that the largest deviations are expected in those components with less impact on the indirect measure of fitness. Here, we show that this simple probabilistic rule explains deviations from optimality in two very different biological systems. In Caenorhabditis elegans, this rule successfully explains the experimental deviations of the position of neurons from the configuration of minimal wiring cost. In Escherichia coli, the probabilistic rule correctly obtains the structure of the experimental deviations of metabolic fluxes from the configuration that maximizes biomass production. This approach is proposed to explain or predict more data than optimization theory while using no extra parameters. Thus, it can also be used to find and refine hypotheses about which constraints have shaped biological structures in evolution.
George Marsaglia
2006-05-01
Full Text Available This article extends and amplifies on results from a paper of over forty years ago. It provides software for evaluating the density and distribution functions of the ratio z/w for any two jointly normal variates z,w, and provides details on methods for transforming a general ratio z/w into a standard form, (a+x/(b+y , with x and y independent standard normal and a, b non-negative constants. It discusses handling general ratios when, in theory, none of the moments exist yet practical considerations suggest there should be approximations whose adequacy can be verified by means of the included software. These approximations show that many of the ratios of normal variates encountered in practice can themselves be taken as normally distributed. A practical rule is developed: If a < 2.256 and 4 < b then the ratio (a+x/(b+y is itself approximately normally distributed with mean μ = a/(1.01b − .2713 and variance 2 = (a2 + 1/(b2 + .108b − 3.795 − μ2.
George Marsaglia
2006-05-01
Full Text Available This article extends and amplifies on results from a paper of over forty years ago. It provides software for evaluating the density and distribution functions of the ratio z/w for any two jointly normal variates z,w, and provides details on methods for transforming a general ratio z/w into a standard form, (a+x/(b+y , with x and y independent standard normal and a, b non-negative constants. It discusses handling general ratios when, in theory, none of the moments exist yet practical considerations suggest there should be approximations whose adequacy can be verified by means of the included software. These approximations show that many of the ratios of normal variates encountered in practice can themselves be taken as normally distributed. A practical rule is developed: If a < 2.256 and 4 < b then the ratio (a+x/(b+y is itself approximately normally distributed with mean μ = a/(1.01b - .2713 and variance σ2 = (a2 + 1/(b2 + .108b - 3.795 μ2.
Fluctuations and large deviations in non-equilibrium systems
B Derrida
2005-05-01
For systems in contact with two reservoirs at different densities or with two thermostats at different temperatures, the large deviation function of the density gives a possible way of extending the notion of free energy to non-equilibrium systems. This large deviation function of the density can be calculated explicitly for exclusion models in one dimension with open boundary conditions. For these models, one can also obtain the distribution of the current of particles flowing through the system and the results lead to a simple conjecture for the large deviation function of the current of more general diffusive systems.
Wiltafsky, M K; Bartelt, J; Relandeau, C; Roth, F X
2009-08-01
Two growth assays and 1 N balance trial were conducted to determine the standardized ileal digestible (SID) Ile:Lys ratio in 8- to 25-kg pigs using spray-dried blood cells or corn gluten feed as a protein source. In Exp. 1, 48 individually penned pigs (initial BW = 7.7 kg) were used in a 6-point SID Ile titration study (analyzed SID Ile of 0.36, 0.43, 0.50, 0.57, 0.64, and 0.72%) by addition of graded levels of L-Ile. The basal diet contained 1.00% SID Lys, 18.4% CP, and 13.6 MJ of ME/kg. Diets were based on wheat, barley, corn, and 7.5% spray-dried blood cells as a protein source. Dietary SID Leu and Val levels were 1.61 and 1.02%, respectively. For the 35-d period, ADG, ADFI, and G:F increased linearly (P < 0.01) and quadratically (P < 0.04) with increasing SID Ile:Lys. Estimates of optimal SID Ile:Lys ratios were 59% for ADG and ADFI. In Exp. 2, 24 N balances were conducted using the Exp. 1 diets (12 pigs; individually penned; average BW = 11.5 kg). Pigs were fed 3 times daily with an amount equal to 1.0 MJ of ME/kg of BW(0.75). Preparation and collection periods (7 d each) were repeated after rearranging the animals to treatments. Increasing the dietary SID Ile:Lys ratio increased N retention linearly (P < 0.01), and N utilization linearly (P < 0.01) and quadratically (P < 0.01). An optimal SID Ile:Lys ratio of 54% was estimated for N retention. In Exp. 3, 48 individually penned pigs (initial BW = 8.0 kg) were fed grain-based diets in a 6-point SID Ile titration (analyzed SID Ile of 0.35, 0.41, 0.49, 0.56, 0.62, and 0.69%). Dietary SID Ile was increased by graded addition of L-Ile. The basal diet contained 0.97% SID Lys, 16.8% CP, and 13.6 MJ of ME/kg. In contrast to Exp. 1 and 2, spray-dried blood cells were excluded and corn gluten feed was used as a protein source. Dietary SID Leu and Val were set to 1.05 and 0.66%. For the 42-d period, ADG, ADFI, and G:F increased linearly (P < 0.01) and quadratically (P < 0.01) with increasing SID Ile:Lys. Estimated
Velocity Structure Determination Through Seismic Waveform Modeling and Time Deviations
Savage, B.; Zhu, L.; Tan, Y.; Helmberger, D. V.
2001-12-01
Through the use of seismic waveforms recorded by TriNet, a dataset of earthquake focal mechanisms and deviations (time shifts) relative to a standard model facilitates the investigation of the crust and uppermost mantle of southern California. The CAP method of focal mechanism determination, in use by TriNet on a routine basis, provides time shifts for surface waves and Pnl arrivals independently relative to the reference model. These shifts serve as initial data for calibration of local and regional seismic paths. Time shifts from the CAP method are derived by splitting the Pnl section of the waveform, the first arriving Pn to just before the arrival of the S wave, from the much slower surface waves then cross-correlating the data with synthetic waveforms computed from a standard model. Surface waves interact with the entire crust, but the upper crust causes the greatest effect. Whereas, Pnl arrivals sample the deeper crust, upper mantle, and source region. This natural division separates the upper from lower crust for regional calibration and structural modeling and allows 3-D velocity maps to be created using the resulting time shifts. Further examination of Pnl and other arrivals which interact with the Moho illuminate the complex nature of this boundary. Initial attempts at using the first 10 seconds of the Pnl section to determine upper most mantle structure have proven insightful. Two large earthquakes north of southern California in Nevada and Mammoth Lakes, CA allow the creation of record sections from 200 to 600 km. As the paths swing from east to west across southern California, simple 1-D models turn into complex structure, dramatically changing the waveform character. Using finite difference models to explain the structure, we determine that a low velocity zone is present at the base of the crust and extends to 100 km in depth. Velocity variations of 5 percent of the mantle in combination with steeply sloping edges produces complex waveform variations
Deviation of the statistical fluctuation in heterogeneous anomalous diffusion
Itto, Yuichi
2016-01-01
The exponent of anomalous diffusion of virus in cytoplasm of a living cell is experimentally known to fluctuate depending on localized areas of the cytoplasm, indicating heterogeneity of diffusion. In a recent paper (Itto, 2012), a maximum-entropy-principle approach has been developed in order to propose an Ansatz for the statistical distribution of such exponent fluctuations. Based on this approach, here the deviation of the statistical distribution of the fluctuations from the proposed one is studied from the viewpoint of Einstein's theory of fluctuations (of the thermodynamic quantities). This may present a step toward understanding the statistical property of the deviation. It is shown in a certain class of small deviations that the deviation obeys the multivariate Gaussian distribution.
A Hybrid Method with Deviational Particles for Spatial Inhomogeneous Plasma
Yan, Bokai
2015-01-01
In this work we propose a Hybrid method with Deviational Particles (HDP) for a plasma modeled by the inhomogeneous Vlasov-Poisson-Landau system. We split the distribution into a Maxwellian part evolved by a grid based fluid solver and a deviation part simulated by numerical particles. These particles, named deviational particles, could be both positive and negative. We combine the Monte Carlo method proposed in \\cite{YC15}, a Particle in Cell method and a Macro-Micro decomposition method \\cite{BLM08} to design an efficient hybrid method. Furthermore, coarse particles are employed to accelerate the simulation. A particle resampling technique on both deviational particles and coarse particles is also investigated and improved. The efficiency is significantly improved compared to a PIC-MCC method, especially near the fluid regime.
Spin-geodesic deviations in the Schwarzschild spacetime
Bini, Donato; Geralico, Andrea; Jantzen, Robert T.
2011-04-01
The deviation of the path of a spinning particle from a circular geodesic in the Schwarzschild spacetime is studied by an extension of the idea of geodesic deviation. Within the Mathisson-Papapetrou-Dixon model and assuming the spin parameter to be sufficiently small so that it makes sense to linearize the equations of motion in the spin variables as well as in the geodesic deviation, the spin-curvature force adds an additional driving term to the second order system of linear ordinary differential equations satisfied by nearby geodesics. Choosing initial conditions for geodesic motion leads to solutions for which the deviations are entirely due to the spin-curvature force, and one finds that the spinning particle position for a given fixed total spin oscillates roughly within an ellipse in the plane perpendicular to the motion, while the azimuthal motion undergoes similar oscillations plus an additional secular drift which varies with spin orientation.
Spin-geodesic deviations in the Schwarzschild spacetime
Bini, Donato; Jantzen, Robert T
2014-01-01
The deviation of the path of a spinning particle from a circular geodesic in the Schwarzschild spacetime is studied by an extension of the idea of geodesic deviation. Within the Mathisson-Papapetrou-Dixon model and assuming the spin parameter to be sufficiently small so that it makes sense to linearize the equations of motion in the spin variables as well as in the geodesic deviation, the spin-curvature force adds an additional driving term to the second order system of linear ordinary differential equations satisfied by nearby geodesics. Choosing initial conditions for geodesic motion leads to solutions for which the deviations are entirely due to the spin-curvature force, and one finds that the spinning particle position for a given fixed total spin oscillates roughly within an ellipse in the plane perpendicular to the motion, while the azimuthal motion undergoes similar oscillations plus an additional secular drift which varies with spin orientation.
Large Deviations for Multi-valued Stochastic Differential Equations
Ren, Jiagang; Zhang, Xicheng
2009-01-01
We prove a large deviation principle of Freidlin-Wentzell's type for the multivalued stochastic differential equations with monotone drifts, which in particular contains a class of SDEs with reflection in a convex domain.
Static large deviations of boundary driven exclusion processes
Farfan, Jonathan
2009-01-01
We prove that the stationary measure associated to a boundary driven exclusion process in any dimension satisfies a large deviation principle with rate function given by the quasi potential of the Freidlin and Wentzell theory.
ALTERNATING HYPERPHORIA - DISSOCIATED VERTICAL DEVIATION (DVD) OCCLUSION HYPERPHORIA
HOUTMAN, WA; ROZE, JH; DEVRIES, B; LETSCH, MC
1991-01-01
Alternating hyperphoria (synonyms: dissociated vertical deviation (DVD) or occlusion hyperphoria) and variants like 'unilateral patching hyperphoria' ('periodic vertical squint') and monocular vertical nystagmus, which may arise after strabismus operations or loss of the function of one of the eyes,
Large Deviations: An Introduction to 2007 Abel Prize
S Ramasubramanian
2008-05-01
2007 Abel prize has been awarded to S R S Varadhan for creating a unified theory of large deviations. We attempt to give a flavour of this branch of probability theory, highlighting the role of Varadhan.
Quenched moderate deviations principle for random walk in random environment
无
2010-01-01
We derive a quenched moderate deviations principle for the one-dimensional nearest random walk in random environment,where the environment is assumed to be stationary and ergodic.The approach is based on hitting time decomposition.
General Freidlin-Wentzell large deviations and positive diffusions
P. Baldi; Caramellino, L.
2011-01-01
Abstract We prove Freidlin-Wentzell Large Deviation estimates under rather minimal assumptions. This allows to derive Wentzell-Freidlin Large Deviation estimates for diffusions on the positive half line with coefficients that are neither bounded nor Lipschitz continuous. This applies to models of interest in Finance, i.e. the CIR and the CEV models, which are positive diffusion processes whose diffusion coefficient is only Holder continuous. correspondence: C...
The Analysis of a Deviation of Investment and Corporate Governance.
HISA Shoichi
2008-01-01
Investment of firms is affected by not only fundamentals factors, but liquidity constraint, ownership or corporate structure. Information structure between manager and owner is a significant factor to decide the level of investment, and deviation of investment from optimal condition. The reputation model between manager and owner suggest that the separate of ownership and management may induce the deviation of investment, and indicate that governance structure is important to reduce it. In th...
Large Deviations and a Fluctuation Symmetry for Chaotic Homeomorphisms
Maes, Christian; Verbitskiy, Evgeny
We consider expansive homeomorphisms with the specification property. We give a new simple proof of a large deviation principle for Gibbs measures corresponding to a regular potential and we establish a general symmetry of the rate function for the large deviations of the antisymmetric part, under time-reversal, of the potential. This generalizes the Gallavotti-Cohen fluctuation theorem to a larger class of chaotic systems.
Perception of midline deviations in smile esthetics by laypersons
Ferreira, Jamille Barros; da Silva, Licínio Esmeraldo; Caetano, Márcia Tereza de Oliveira; da Motta, Andrea Fonseca Jardim; Cury-Saramago, Adriana de Alcantara; Mucha, José Nelson
2016-01-01
ABSTRACT Objective: To evaluate the esthetic perception of upper dental midline deviation by laypersons and if adjacent structures influence their judgment. Methods: An album with 12 randomly distributed frontal view photographs of the smile of a woman with the midline digitally deviated was evaluated by 95 laypersons. The frontal view smiling photograph was modified to create from 1 mm to 5 mm deviations in the upper midline to the left side. The photographs were cropped in two different manners and divided into two groups of six photographs each: group LCN included the lips, chin, and two-thirds of the nose, and group L included the lips only. The laypersons performed the rate of each smile using a visual analog scale (VAS). Wilcoxon test, Student’s t-test and Mann-Whitney test were applied, adopting a 5% level of significance. Results: Laypersons were able to perceive midline deviations starting at 1 mm. Statistically significant results (p< 0.05) were found for all multiple comparisons of the values in photographs of group LCN and for almost all comparisons in photographs of group L. Comparisons between the photographs of groups LCN and L showed statistically significant values (p< 0.05) when the deviation was 1 mm. Conclusions: Laypersons were able to perceive the upper dental midline deviations of 1 mm, and above when the adjacent structures of the smiles were included. Deviations of 2 mm and above when the lips only were included. The visualization of structures adjacent to the smile demonstrated influence on the perception of midline deviation. PMID:28125140
Perception of midline deviations in smile esthetics by laypersons
Jamille Barros Ferreira
Full Text Available ABSTRACT Objective: To evaluate the esthetic perception of upper dental midline deviation by laypersons and if adjacent structures influence their judgment. Methods: An album with 12 randomly distributed frontal view photographs of the smile of a woman with the midline digitally deviated was evaluated by 95 laypersons. The frontal view smiling photograph was modified to create from 1 mm to 5 mm deviations in the upper midline to the left side. The photographs were cropped in two different manners and divided into two groups of six photographs each: group LCN included the lips, chin, and two-thirds of the nose, and group L included the lips only. The laypersons performed the rate of each smile using a visual analog scale (VAS. Wilcoxon test, Student’s t-test and Mann-Whitney test were applied, adopting a 5% level of significance. Results: Laypersons were able to perceive midline deviations starting at 1 mm. Statistically significant results (p< 0.05 were found for all multiple comparisons of the values in photographs of group LCN and for almost all comparisons in photographs of group L. Comparisons between the photographs of groups LCN and L showed statistically significant values (p< 0.05 when the deviation was 1 mm. Conclusions: Laypersons were able to perceive the upper dental midline deviations of 1 mm, and above when the adjacent structures of the smiles were included. Deviations of 2 mm and above when the lips only were included. The visualization of structures adjacent to the smile demonstrated influence on the perception of midline deviation.
A phase deviation based split-spectrum processing algorithm for ultrasonic flaw detection
LIU Zhenqing
2002-01-01
The Split Spectrum Processing (SSP) technique has proved its ability in reduction of interference noise in ultrasonic nondestructive testing for coarse grained materials. However,the results of SSP algorithms are not sufficiently stable since they are sensitive to the filter bank and filter parameters. And the mechanism of the technique to fully explore the signals is not clear. The statistical phase response characteristic of filter outputs for ultrasonic testing is discussed. Thus, a new SSP algorithm based on phase standard deviation is proposed. The performance is examined for both computer simulated and experimental data, and compared to commonly used minimum algorithm. The phase standard deviation algorithm is proved its superior effect and is less sensitive on the number of filters.
Nasal Septal Deviations: A Systematic Review of Classification Systems
Jeffrey Teixeira
2016-01-01
Full Text Available Objective. To systematically review the international literature for internal nasal septal deviation classification systems and summarize them for clinical and research purposes. Data Sources. Four databases (including PubMed/MEDLINE were systematically searched through December 16, 2015. Methods. Systematic review, adhering to PRISMA. Results. After removal of duplicates, this study screened 952 articles for relevance. A final comprehensive review of 50 articles identified that 15 of these articles met the eligibility criteria. The classification systems defined in these articles included C-shaped, S-shaped, reverse C-shaped, and reverse S-shaped descriptions of the septal deviation in both the cephalocaudal and anteroposterior dimensions. Additional studies reported use of computed tomography and categorized deviation based on predefined locations. Three studies graded the severity of septal deviations based on the amount of deflection. The systems defined in the literature also included an evaluation of nasal septal spurs and perforations. Conclusion. This systematic review ascertained that the majority of the currently published classification systems for internal nasal septal deviations can be summarized by C-shaped or reverse C-shaped, as well as S-shaped or reverse S-shaped deviations in the anteroposterior and cephalocaudal dimensions. For imaging studies, predefined points have been defined along the septum. Common terminology can facilitate future research.
Nasal Septal Deviations: A Systematic Review of Classification Systems
Teixeira, Jeffrey; Certal, Victor; Chang, Edward T.; Camacho, Macario
2016-01-01
Objective. To systematically review the international literature for internal nasal septal deviation classification systems and summarize them for clinical and research purposes. Data Sources. Four databases (including PubMed/MEDLINE) were systematically searched through December 16, 2015. Methods. Systematic review, adhering to PRISMA. Results. After removal of duplicates, this study screened 952 articles for relevance. A final comprehensive review of 50 articles identified that 15 of these articles met the eligibility criteria. The classification systems defined in these articles included C-shaped, S-shaped, reverse C-shaped, and reverse S-shaped descriptions of the septal deviation in both the cephalocaudal and anteroposterior dimensions. Additional studies reported use of computed tomography and categorized deviation based on predefined locations. Three studies graded the severity of septal deviations based on the amount of deflection. The systems defined in the literature also included an evaluation of nasal septal spurs and perforations. Conclusion. This systematic review ascertained that the majority of the currently published classification systems for internal nasal septal deviations can be summarized by C-shaped or reverse C-shaped, as well as S-shaped or reverse S-shaped deviations in the anteroposterior and cephalocaudal dimensions. For imaging studies, predefined points have been defined along the septum. Common terminology can facilitate future research. PMID:26933510
Sex Ratio Elasticity Influences the Selection of Sex Ratio Strategy
Wang, Yaqiang; Wang, Ruiwu; Li, Yaotang; (Sam) Ma, Zhanshan
2016-01-01
There are three sex ratio strategies (SRS) in nature—male-biased sex ratio, female-biased sex ratio and, equal sex ratio. It was R. A. Fisher who first explained why most species in nature display a sex ratio of ½. Consequent SRS theories such as Hamilton’s local mate competition (LMC) and Clark’s local resource competition (LRC) separately explained the observed deviations from the seemingly universal 1:1 ratio. However, to the best of our knowledge, there is not yet a unified theory that accounts for the mechanisms of the three SRS. Here, we introduce the price elasticity theory in economics to define sex ratio elasticity (SRE), and present an analytical model that derives three SRSs based on the following assumption: simultaneously existing competitions for both resources A and resources B influence the level of SRE in both sexes differently. Consequently, it is the difference (between two sexes) in the level of their sex ratio elasticity that leads to three different SRS. Our analytical results demonstrate that the elasticity-based model not only reveals a highly plausible mechanism that explains the evolution of SRS in nature, but also offers a novel framework for unifying two major classical theories (i.e., LMC & LRC) in the field of SRS research. PMID:28009000
Sex Ratio Elasticity Influences the Selection of Sex Ratio Strategy
Wang, Yaqiang; Wang, Ruiwu; Li, Yaotang; (Sam) Ma, Zhanshan
2016-12-01
There are three sex ratio strategies (SRS) in nature—male-biased sex ratio, female-biased sex ratio and, equal sex ratio. It was R. A. Fisher who first explained why most species in nature display a sex ratio of ½. Consequent SRS theories such as Hamilton’s local mate competition (LMC) and Clark’s local resource competition (LRC) separately explained the observed deviations from the seemingly universal 1:1 ratio. However, to the best of our knowledge, there is not yet a unified theory that accounts for the mechanisms of the three SRS. Here, we introduce the price elasticity theory in economics to define sex ratio elasticity (SRE), and present an analytical model that derives three SRSs based on the following assumption: simultaneously existing competitions for both resources A and resources B influence the level of SRE in both sexes differently. Consequently, it is the difference (between two sexes) in the level of their sex ratio elasticity that leads to three different SRS. Our analytical results demonstrate that the elasticity-based model not only reveals a highly plausible mechanism that explains the evolution of SRS in nature, but also offers a novel framework for unifying two major classical theories (i.e., LMC & LRC) in the field of SRS research.
Method of determining load in anisotropic non-crystalline materials using energy flux deviation
Prosser, William H. (Inventor); Kriz, Ronald D. (Inventor); Fitting, Dale W. (Inventor)
1994-01-01
An ultrasonic wave is applied to an anisotropic sample material in an initial direction and the intensity of the ultrasonic wave is measured on an opposite surface of the sample material by two adjacent receiving points located in an array of receiving points. A ratio is determined between the measured intensities of two adjacent receiving points, the ratio being indicative of an angle of flux deviation from the initial direction caused by an unknown applied load. This determined ratio is then compared to a plurality of ratios of a similarly tested, similar anisotropic reference material under a plurality of respective, known load conditions, whereby the load applied to the particular anisotropic sample material is determined. A related method is disclosed for determining the fiber orientation from known loads and a determined flux shift.
Smith, Russell J.; Lucey, John R.; Edge, Alastair C.
2017-10-01
We analyse the stellar kinematics of the z = 0.169 brightest cluster galaxy in Abell 1201, using integral field observations acquired with the Multi-Unit Spectroscopic Explorer on the Very Large Telescope. This galaxy has a gravitationally lensed arc located at unusually small radius (∼5 kpc), allowing us to constrain the mass distribution using lensing and stellar dynamical information over the same radial range. We measure a velocity dispersion profile which is nearly flat at σ ≈ 285 km s-1 in the inner ∼5 kpc, and then rises steadily to σ ≈ 360 km s-1 at ∼30 kpc. We analyse the kinematics using axisymmetric Jeans models, finding that the data require both a significant dark matter halo (to fit the rising outer profile) and a compact central component, with mass Mcen ≈ 2.5 × 1010 M⊙ (to fit the flat σ in the inner regions). The latter component could represent a supermassive black hole, in which case it would be among the largest known to date. Alternatively Mcen could describe excess mass associated with a gradient in the stellar mass-to-light ratio. Imposing a standard Navarro-Frenk-White (NFW) dark matter density profile, we recover a stellar mass-to-light ratio ϒ, which is consistent with a Milky Way-like initial mass function (IMF). By anchoring the models using the lensing mass constraint, we break the degeneracy between ϒ and the inner slope γ of the dark matter profile, finding γ = 1.0 ± 0.1, consistent with the NFW form. We show that our results are quite sensitive to the treatment of the central mass in the models. Neglecting Mcen biases the results towards both a heavier-than-Salpeter IMF and a shallower-than-NFW dark matter slope (γ ≈ 0.5).
Knowledge of food and drug administration reportable deviations.
Lam, Rebecca; Bryant, Barbara J
2011-07-01
As early as 2001, the Food and Drug Administration (FDA) required blood centers and hospital transfusion services to report events associated with testing, storage, or distribution of blood products that deviated from current good manufacturing practices or affected the safety, purity, or potency of the product. Between 2004 and 2009, an average of only 8.6% of hospitals reported blood product deviations. Case scenarios designed to evaluate knowledge of FDA reportable deviations were developed and sent for evaluation to the Center for Biologics Evaluation and Research (CBER) and FDA division directors for FDA reportable deviations. A final survey containing eight cases was launched in a web-based online survey tool and sent to blood bank medical technologists. Additional information was queried regarding job title/responsibilities and the size of the blood center and/or transfusion service. There were 176 respondents to the survey. Only 5.7% (10/176) answered all questions correctly. Analysis by job title and place of employment revealed no correlation to the number of correct responses. More importance was attached to deviations involving quality control, blood bank identification, unit specifications, and antibody identification. Less importance was attached to deviations involving phlebotomist's initials, failure to issue units in the computer, and using a recent sample from a previous hospitalization. This study revealed that blood bankers did not have clear understanding of what constituted an FDA reportable occurrence. Size or type of blood establishment or individual job title was not associated with more knowledge of FDA reportable deviations. © 2011 American Association of Blood Banks.
Outcomes of Surgical Treatment in Cases of Dissociated Vertical Deviation
Serpil Akar
2014-03-01
Full Text Available Objectives: To investigate the results of different surgical techniques for treating cases of dissociated vertical deviation (DVD. Materials and Methods: A retrospective review of medical records was performed, including 94 eyes of 47 patients who had undergone bilateral superior rectus (SR recessions (Group 1, bilateral SR recession with posterior fixation sutures (Group 2, or bilateral inferior oblique (IO anterior transposition surgery (Group 3 for treatment of DVD. Nineteen patients underwent secondary procedures (SR weakening or IO anterior transposition because of unsatisfactory results. The amount of the DVD in primary position before and after surgery, postoperative success ratios, and probable complications were evaluated. The Wilcoxon signed ranks test and chi-squared test were used for statistical evaluations. Results: In 69% of the 32 eyes in group 1, 65% of the 20 eyes in group 2, and 79% of the 42 eyes in group 3, satisfactory control of the DVD in primary position was achieved. All eyes undergoing both SR weakening and IO anterior transposition had a residual DVD of less than 5 prism diopters (pd. Of the total of 94 eyes, in 26 (89.6% of 29 eyes that had a preoperative DVD angle of more than 15 pd [ten eyes from group 1, seven eyes from group 2, and nine eyes from group 3], the residual DVD angle after surgery was more than 5 pd. However, in the 65 eyes with preoperative DVD of 15 pd or less (21from Group 1, 12 from Group 2, and 32 from Group 3, the residual DVD angle after the operation was less than 5 pd. Two eyes of 2 patients had -1 limitation to elevation after surgery. Conclusion: Only IO anterior transposition or SR weakening surgery appear to be a successful surgical approaches in the management of patients with mild- and moderate-angle (≤15 pd DVD. Weakening both the SR and IO muscles yield a greater success in the management of patients with large-angle (>15 pd DVD. (Turk J Ophthalmol 2014; 44: 132-7
Cosolvency and deviations from log-linear solubilization.
Rubino, J T; Yalkowsky, S H
1987-06-01
The solubilities of three nonpolar drugs, phenytoin, diazepam, and benzocaine, have been measured in 14 cosolvent-water binary mixtures. The observed solubilities were examined for deviations from solubilities calculated by the equation log Sm = f log Sc + (1 - f) log Sw, where Sm is the solubility of the drug in the cosolvent-water mixture, Sc is the solubility of the drug in neat cosolvent, f is the volume fraction of cosolvent, and Sw is the solubility of the drug in water. When presented graphically, the patterns of the deviations were similar for all three drugs in mixtures of amphiprotic cosolvents (glycols, polyols, and alcohols) and water as well as nonpolar, aprotic cosolvents (dioxane, triglyme, dimethyl isosorbide) and water. The deviations were positive for phenytoin and benzocaine but negative for diazepam in mixtures of dipolar, aprotic cosolvents (dimethylsulfoxide, dimethylformamide, and dimethylacetamide) and water. The source of the deviations could not consistently be attributed to physical properties of the cosolvent-water mixtures or to alterations in the solute crystal. Similarities between the results of this study and those of previous investigations suggest that changes in the structure of the solvent play a role in the deviations from the expected solubilities.
DYSFUNCTION OF THE MODERN RUSSIAN FAMILY AND PROBLEM OF THE DEVIATING SOCIALIZATION OF TEENAGERS
Tatyana I. BARSUKOVA
2015-01-01
Full Text Available In article influence of dysfunction of the family interpreted by authors as a negative consequence of its transformation, on deviations in socialization of teenagers, in their sotsializatsionnykh trajectories, on a gabitualization of "trouble" is analysed. Locates that violation of functioning of a family (its dysfunction in the attitude towards the teenager can be referred to determinants of deviations of socialization. Negative influence of a disfunktsionalnost of a family on formation of the identity of the modern teenager is shown in his deviant acts of a negative orientation now; forms of deviant behavior in which these deviations, and also consequences of refusal of a number of families of performance of economic and economic and protective functions prove are described. Author's definition of the normal and deviating socialization is presented. Attempt to define border between the normal and deviating socialization, between normal sotsializatsionny process and anomiyny, deformable becomes. By authors of article it is proved that the deviating socialization the deviation from sotsializatsionny norm as multidimensional a standard is the cornerstone, of fiksiruyushchy a sotsializirovannost of the person. Definition of sotsializatsionny norm as interval, as admissible in behavior of people and as its regulator is given. The emphasis is placed on a role of trajectory model of socialization which changes depending on influence of a family on socialization of teenagers. The choice locates in article as object of research of the teenager that at such age some "binarity" of the personality, a combination in it of lines, both the adult, and the child is observed. It, according to authors, complicates a choice the teenager of ethical standards and vital values. Besides, variety of alternatives at a choice of norms and behavior models it is complicated by a polinormativnost of social space of the teenager. The
Lin, Jonathan K; Wheatley, Francis C; Handwerker, Jason; Harris, Norman J; Wong, Brian J F
2014-01-01
IMPORTANCE Accurately characterizing nasal septal deviations is valuable for surgical planning, classifying nasal septal deviations, providing a means to accurately perform outcomes research, and understanding the causes of chronic conditions. OBJECTIVE To determine and quantify regions of septal deformity that can be used to develop a comprehensive classification system. DESIGN, SETTING, AND PARTICIPANTS A retrospective case series study was conducted at an academic tertiary care hospital. Sixty-four participants were selected based on a convenience sample of computed tomography (CT) scans of the paranasal sinuses and midface available between June 29, 2011, and August 16, 2012. Exclusion criteria consisted of incomplete or inadequate CT series. The most recent CT scans were chosen for analyses regardless of the indication for imaging. Digital Imaging and Communications in Medicine format bitmap file–formatted data were obtained and analyzed using MATLAB and OsiriX. The line to curve ratio, deviation area, and root mean square (RMS) values of the septal contour vs the ideal straight septum fit were calculated. Analysis was performed to detect significant differences (P < .05) using the 3 measures.MAIN OUTCOMES AND MEASURES Quantitative analysis of nasal septal deviation.RESULTS The population consisted of 50 male and 14 female patients aged 3 to 83 years(mean, 42 years). Mean line to curve ratios, areas, and RMS values were highest in contours that intersected the perpendicular plate–vomer junction, with a mean line to curve ratio of1.04 and mean deviated area of 627.16 arbitrary units (P = .02). Maximal deviation areas were also seen midway from the perpendicular plate–vomer junction to the nasal spine with a mean area of 577.31 arbitrary units (P = .01). The RMS values were significantly elevated along the crista galli and perpendicular plate–vomer junction (P < .05).CONCLUSIONS AND RELEVANCE Maximum septal deviation is seen at the perpendicular plate
Deviations of the distributions of seismic energies from the Gutenberg-Richter law
Pisarenko, V; Rodkin, M
2003-01-01
A new non-parametric statistic is introduced for the characterization of deviations from power laws. It is tested on the distribution of seismic energies given by the Gutenberg-Richter law. Based on the two first statistical log-moments, it evaluates quantitatively the deviations of the distribution of scalar seismic moments from a power-like (Pareto) law. This statistic is close to zero for the Pareto law with arbitrary power index, and deviates from zero for any non-Pareto distribution. A version of this statistic for discrete distribution of quantified magnitudes is also given. A methodology based on this statistics consisting in scanning the lower threshold for earthquake energies provides an explicit visualization of deviations from the Pareto law, surpassing in sensitivity the standard Hill estimator or other known techniques. This new statistical technique has been applied to shallow earthquakes (h < 70 km) both in subduction zones and in mid-ocean ridge zones (using the Harvard catalog of seismic m...
Jacobson, Gloria; Rella, Chris; Farinas, Alejandro
2014-05-01
Technological advancement of instrumentation in atmospheric and other geoscience disciplines over the past decade has lead to a shift from discrete sample analysis to continuous, in-situ monitoring. Standard error analysis used for discrete measurements is not sufficient to assess and compare the error contribution of noise and drift from continuous-measurement instruments, and a different statistical analysis approach should be applied. The Allan standard deviation analysis technique developed for atomic clock stability assessment by David W. Allan [1] can be effectively and gainfully applied to continuous measurement instruments. As an example, P. Werle et al has applied these techniques to look at signal averaging for atmospheric monitoring by Tunable Diode-Laser Absorption Spectroscopy (TDLAS) [2]. This presentation will build on, and translate prior foundational publications to provide contextual definitions and guidelines for the practical application of this analysis technique to continuous scientific measurements. The specific example of a Picarro G2401 Cavity Ringdown Spectroscopy (CRDS) analyzer used for continuous, atmospheric monitoring of CO2, CH4 and CO will be used to define the basics features the Allan deviation, assess factors affecting the analysis, and explore the time-series to Allan deviation plot translation for different types of instrument noise (white noise, linear drift, and interpolated data). In addition, the useful application of using an Allan deviation to optimize and predict the performance of different calibration schemes will be presented. Even though this presentation will use the specific example of the Picarro G2401 CRDS Analyzer for atmospheric monitoring, the objective is to present the information such that it can be successfully applied to other instrument sets and disciplines. [1] D.W. Allan, "Statistics of Atomic Frequency Standards," Proc, IEEE, vol. 54, pp 221-230, Feb 1966 [2] P. Werle, R. Miicke, F. Slemr, "The Limits
Novitskaia, Ia G; Gribakina, O G; Kolyvanov, G B; Zherdev, V P; Smirnov, V V; Seredenin, S B
2013-01-01
The effect of subchronic peroral administration in effective doses of afobazole (5 mg/kg), and cytochrome P450 inductors (rifampicin, 13.4 mg/kg; phenytoin, 10.4 mg/kg) and inhibitors (fluconazole, 35.7 mg/kg; ciprofloxacin, 44.0 mg/kg) on the metabolic ratio (MR) of drugs-markers of CYP2C9 and CYP1A2 activity was studied in rats. Afobazole did not change the MR of compounds metabolized by the P450 isoforms studied. After peroral administration of standard P450 inductors and inhibitors, statistically significant bidirectional effects were identified, which demonstrated the expedience of administering a complex of selected compounds, markers, and CYP2C9 and CYP1A2 activity modificators for comparative evaluation of the effects of new drugs in rats. It is recommended to evaluate the activity of CYP1A2 by determining the MR for one of two caffeine metabolites, paraxanthine or theobromine, and the activity of CYP2C9 by determining the MR of metabolite Exp-3174 to losartan.
Scaling Deviations for Neutrino Reactions in Aysmptotically Free Field Theories
Wilczek, F. A.; Zee, A.; Treiman, S. B.
1974-11-01
Several aspects of deep inelastic neutrino scattering are discussed in the framework of asymptotically free field theories. We first consider the growth behavior of the total cross sections at large energies. Because of the deviations from strict scaling which are characteristic of such theories the growth need not be linear. However, upper and lower bounds are established which rather closely bracket a linear growth. We next consider in more detail the expected pattern of scaling deviation for the structure functions and, correspondingly, for the differential cross sections. The analysis here is based on certain speculative assumptions. The focus is on qualitative effects of scaling breakdown as they may show up in the X and y distributions. The last section of the paper deals with deviations from the Callan-Gross relation.
Minimizing Hexapod Robot Foot Deviations Using Multilayer Perceptron
Vytautas Valaitis
2015-12-01
Full Text Available Rough-terrain traversability is one of the most valuable characteristics of walking robots. Even despite their slower speeds and more complex control algorithms, walking robots have far wider usability than wheeled or tracked robots. However, efficient movement over irregular surfaces can only be achieved by eliminating all possible difficulties, which in many cases are caused by a high number of degrees of freedom, feet slippage, frictions and inertias between different robot parts or even badly developed inverse kinematics (IK. In this paper we address the hexapod robot-foot deviation problem. We compare the foot-positioning accuracy of unconfigured inverse kinematics and Multilayer Perceptron-based (MLP methods via theory, computer modelling and experiments on a physical robot. Using MLP-based methods, we were able to significantly decrease deviations while reaching desired positions with the hexapod’s foot. Furthermore, this method is able to compensate for deviations of the robot arising from any possible reason.
Exact Large Deviation Function in the Asymmetric Exclusion Process
Derrida, Bernard; Lebowitz, Joel L.
1998-01-01
By an extension of the Bethe ansatz method used by Gwa and Spohn, we obtain an exact expression for the large deviation function of the time averaged current for the fully asymmetric exclusion process in a ring containing N sites and p particles. Using this expression we easily recover the exact diffusion constant obtained earlier and calculate as well some higher cumulants. The distribution of the deviation y of the average current is, in the limit N-->∞, skew and decays like exp-\\(Ay5/2\\) for y-->+∞ and exp-\\(A'\\|y\\|3/2\\) for y-->-∞. Surprisingly, the large deviation function has an expression very similar to the pressure (as a function of the density) of an ideal Bose or Fermi gas in 3D.
Mean-deviation analysis in the theory of choice.
Grechuk, Bogdan; Molyboha, Anton; Zabarankin, Michael
2012-08-01
Mean-deviation analysis, along with the existing theories of coherent risk measures and dual utility, is examined in the context of the theory of choice under uncertainty, which studies rational preference relations for random outcomes based on different sets of axioms such as transitivity, monotonicity, continuity, etc. An axiomatic foundation of the theory of coherent risk measures is obtained as a relaxation of the axioms of the dual utility theory, and a further relaxation of the axioms are shown to lead to the mean-deviation analysis. Paradoxes arising from the sets of axioms corresponding to these theories and their possible resolutions are discussed, and application of the mean-deviation analysis to optimal risk sharing and portfolio selection in the context of rational choice is considered.
Spin-geodesic deviations in the Kerr spacetime
Bini, D.; Geralico, A.
2011-11-01
The dynamics of extended spinning bodies in the Kerr spacetime is investigated in the pole-dipole particle approximation and under the assumption that the spin-curvature force only slightly deviates the particle from a geodesic path. The spin parameter is thus assumed to be very small and the back reaction on the spacetime geometry neglected. This approach naturally leads to solve the Mathisson-Papapetrou-Dixon equations linearized in the spin variables as well as in the deviation vector, with the same initial conditions as for geodesic motion. General deviations from generic geodesic motion are studied, generalizing previous results limited to the very special case of an equatorial circular geodesic as the reference path.
Spin-geodesic deviations in the Kerr spacetime
Bini, Donato
2014-01-01
The dynamics of extended spinning bodies in the Kerr spacetime is investigated in the pole-dipole particle approximation and under the assumption that the spin-curvature force only slightly deviates the particle from a geodesic path. The spin parameter is thus assumed to be very small and the back reaction on the spacetime geometry neglected. This approach naturally leads to solve the Mathisson-Papapetrou-Dixon equations linearized in the spin variables as well as in the deviation vector, with the same initial conditions as for geodesic motion. General deviations from generic geodesic motion are studied, generalizing previous results limited to the very special case of an equatorial circular geodesic as the reference path.
Large deviation theory for coin tossing and turbulence.
Chakraborty, Sagar; Saha, Arnab; Bhattacharjee, Jayanta K
2009-11-01
Large deviations play a significant role in many branches of nonequilibrium statistical physics. They are difficult to handle because their effects, though small, are not amenable to perturbation theory. Even the Gaussian model, which is the usual initial step for most perturbation theories, fails to be a starting point while discussing intermittency in fluid turbulence, where large deviations dominate. Our contention is: in the large deviation theory, the central role is played by the distribution associated with the tossing of a coin and the simple coin toss is the "Gaussian model" of problems where rare events play significant role. We illustrate this by applying it to calculate the multifractal exponents of the order structure factors in fully developed turbulence.
Deviations From Newton's Law in Supersymmetric Large Extra Dimensions
Callin, P
2006-01-01
Deviations from Newton's Inverse-Squared Law at the micron length scale are smoking-gun signals for models containing Supersymmetric Large Extra Dimensions (SLEDs), which have been proposed as approaches for resolving the Cosmological Constant Problem. Just like their non-supersymmetric counterparts, SLED models predict gravity to deviate from the inverse-square law because of the advent of new dimensions at sub-millimeter scales. However SLED models differ from their non-supersymmetric counterparts in three important ways: (i) the size of the extra dimensions is fixed by the observed value of the Dark Energy density, making it impossible to shorten the range over which new deviations from Newton's law must be seen; (ii) supersymmetry predicts there to be more fields in the extra dimensions than just gravity, implying different types of couplings to matter and the possibility of repulsive as well as attractive interactions; and (iii) the same mechanism which is purported to keep the cosmological constant natu...
Heterodyne Angle Deviation Interferometry in Vibration and Bubble Measurements
Ming-Hung Chiu
2016-07-01
Full Text Available We proposed heterodyne angle deviation interferometry (HADI for angle deviation measurements. The phase shift of an angular sensor (which can be a metal film or a surface plasmon resonance (SPR prism is proportional to the deviation angle of the test beam. The method has been demonstrated in bubble and speaker’s vibration measurements in this paper. In the speaker’s vibration measurement, the voltage from the phase channel of a lock-in amplifier includes the vibration level and frequency. In bubble measurement, we can count the number of bubbles passing through the cross section of the laser beam and measure the bubble size from the phase pulse signal.
Elzanfaly, Eman S; Hassan, Said A; Salem, Maissa Y; El-Zeany, Badr A
2015-04-01
Five signal processing techniques were applied to ratio spectra for quantitative determination of bisoprolol (BIS) and hydrochlorothiazide (HCT) in their binary mixture. The proposed techniques are Numerical Differentiation of Ratio Spectra (ND-RS), Savitsky-Golay of Ratio Spectra (SG-RS), Continuous Wavelet Transform of Ratio Spectra (CWT-RS), Mean Centering of Ratio Spectra (MC-RS) and Discrete Fourier Transform of Ratio Spectra (DFT-RS). The linearity of the proposed methods was investigated in the range of 2-40 and 1-22 μg/mL for BIS and HCT, respectively. The proposed methods were applied successfully for the determination of the drugs in laboratory prepared mixtures and in commercial pharmaceutical preparations and standard deviation was less than 1.5. The five signal processing techniques were compared to each other and validated according to the ICH guidelines and accuracy, precision, repeatability and robustness were found to be within the acceptable limit.
Deviation of eyes and head in acute cerebral stroke
Ilg UJ
2006-06-01
Full Text Available Abstract Background It is a well-known phenomenon that some patients with acute left or right hemisphere stroke show a deviation of the eyes (Prévost's sign and head to one side. Here we investigated whether both right- and left-sided brain lesions may cause this deviation. Moreover, we studied the relationship between this phenomenon and spatial neglect. In contrast to previous studies, we determined not only the discrete presence or absence of eye deviation with the naked eye through clinical inspection, but actually measured the extent of horizontal eye-in-head and head-on-trunk deviation. In further contrast, measurements were performed early after stroke onset (1.5 days on average. Methods Eye-in-head and head-on-trunk positions were measured at the bedside in 33 patients with acute unilateral left or right cerebral stroke consecutively admitted to our stroke unit. Results Each single patient with spatial neglect and right hemisphere lesion showed a marked deviation of the eyes and the head to the ipsilesional, right side. The average spontaneous gaze position in this group was 46° right, while it was close to the saggital body midline (0° in the groups with acute left- or right-sided stroke but no spatial neglect as well as in healthy subjects. Conclusion A marked horizontal eye and head deviation observed ~1.5 days post-stroke is not a symptom associated with acute cerebral lesions per se, nor is a general symptom of right hemisphere lesions, but rather is specific for stroke patients with spatial neglect. The evaluation of the patient's horizontal eye and head position thus could serve as a brief and easy way helping to diagnose spatial neglect, in addition to the traditional paper-and-pencil tests.
Moderate Deviation Principles for Stochastic Differential Equations with Jumps
2014-01-15
random measure and an in�nite dimensional Brownian motion) was derived. As in the Brownian motion case, the representation is motivated in part by...deviations of a smaller order than in large deviation theory . Consider for example an independent and identically distributed (iid) sequence fYigi1 of...8217") " E " 1 2 Z X[0;T ] ( ")21fj "jB"gdT + F G "("N " 1’") # " 1 2 3M 2(1); (3.6) where the last inequality follows from (3.5) on
Influence of Deviation on Optical Transmission through Aperiodic Superlattices
YIN Hai-Long; YANG Xiang-Bo; LAN Sheng; HU Wei
2007-01-01
We propose a deviation model and study the influences of the relative error and sensitivity of a machine on the transmission coefficients (TCs) of Fibonacci superlattices. It is found that for a system with fewer layers, the influence of deviation can be ignored. When superlattices become more complicated, they may be fabricated by a machine with suitable relative error and possess the designed value of TC. However, when the number of system layers exceeds some critical value, superlattices should be manufactured only by precise machines. The influence of the sensitivity is also discussed.
Small shape deviations causes complex dynamics in large electric generators
Lundström, Niklas L. P.; Grafström, Anton; Aidanpää, Jan-Olov
2014-05-01
We prove that combinations of small eccentricity, ovality and/or triangularity in the rotor and stator can produce complex whirling motions of an unbalanced rotor in large synchronous generators. It is concluded which structures of shape deviations that are more harmful, in the sense of producing complex whirling motions, than others. For each such structure, we derive simplified equations of motions from which we conclude analytically the relation between shape deviations and mass unbalance that yield non-smooth whirling motions. Finally we discuss validity of our results in the sense of modeling of the unbalanced magnetic pull force.
Sample-path Large Deviations in Credit Risk
Leijdekker, Vincent; Spreij, Peter
2009-01-01
The event of large losses plays an important role in credit risk. As these large losses are typically rare, and portfolios usually consist of a large number of positions, large deviation theory is the natural tool to analyze the tail asymptotics of the probabilities involved. We first derive a sample-path large deviation principle (LDP) for the portfolio's loss process, which enables the computation of the logarithmic decay rate of the probabilities of interest. In addition, we derive exact asymptotic results for a number of specific rare-event probabilities, such as the probability of the loss process exceeding some given function.
UNUSUAL SEXUAL DEVIATIONS IN A YOUNG MAN: A CASE REPORT
John Dinesh
2014-08-01
Full Text Available Sexual deviance in human refers to abnormal sexual expression. Though it is very difficult to exactly say what is normal or abnormal in sexual relationships, some sexual behaviors are clearly documented as abnormal in our society. Paraphilias or perversions are sexual stimuli or acts that are deviations from normal sexual behaviors, but are necessary for some individual’s to experience arousal and orgasm. Here we discuss abnormal sexual deviations in a young married male who presented with just feelings of guilt and without any psychosocial dysfunctions because of his uncommon sexual perversions.
Living at the Edge: A Large Deviations Approach to the Outage MIMO Capacity
Kazakopoulos, P; Moustakas, A L; Caire, G
2009-01-01
Using a large deviations approach we calculate the probability distribution of the mutual information of MIMO channels in the limit of large antenna numbers. In contrast to previous methods that only focused at the distribution close to its mean (thus obtaining an asymptotically Gaussian distribution), we calculate the full distribution, including its tails which strongly deviate from the Gaussian behavior near the mean. The resulting distribution interpolates seamlessly between the Gaussian approximation for rates $R$ close to the ergodic value of the mutual information and the approach of Zheng and Tse for large signal to noise ratios $\\rho$. This calculation provides us with a tool to obtain outage probabilities analytically at any point in the $(R, \\rho, N)$ parameter space, as long as the number of antennas $N$ is not too small. In addition, this method also yields the probability distribution of eigenvalues constrained in the subspace where the mutual information per antenna is fixed to $R$ for a given ...
Darwish, Hany W.; Hassan, Said A.; Salem, Maissa Y.; El-Zeiny, Badr A.
2011-12-01
Three simple, specific, accurate and precise spectrophotometric methods manipulating ratio spectra are developed for the simultaneous determination of Amlodipine besylate (AM) and Atorvastatin calcium (AT) in tablet dosage forms. The first method is first derivative of the ratio spectra ( 1DD), the second is ratio subtraction and the third is the method of mean centering of ratio spectra. The calibration curve is linear over the concentration range of 3-40 and 8-32 μg/ml for AM and AT, respectively. These methods are tested by analyzing synthetic mixtures of the above drugs and they are applied to commercial pharmaceutical preparation of the subjected drugs. Standard deviation is <1.5 in the assay of raw materials and tablets. Methods are validated as per ICH guidelines and accuracy, precision, repeatability and robustness are found to be within the acceptable limit.
Fat to muscle ratio measurements with dual energy x-ray absorbtiometry
Chen, A. [Shenzhen College of International Education, 1st HuangGang Park St., Shenzhen, GuangDong (China); Luo, J. [Department of Biomedical Engineering, University at Buffalo, 332 Bonner Hall, Buffalo, NY 14260-1920 (United States); Wang, A. [Department of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213 (United States); Broadbent, C. [School of Engineering, Columbia University, 1130 Amsterdam Av., New York, NY 10027 (United States); Zhong, J. [Department of English, Dartmouth College, 6032 Sanborn House, Hanover, NH 03755 (United States); Dilmanian, F.A. [Departments of Radiation Oncology, Neurology, and Radiology, Stony Brook University, Stony Brook, NY 11794 (United States); Zafonte, F.; Zhong, Z. [National Synchrotron Light Source II, Brookhaven National Laboratory, Bldg. 743, Upton, NY 11973 (United States)
2015-07-11
Accurate measurement of the fat-to-muscle ratio in animal model is important for obesity research. An efficient way to measure the fat to muscle ratio in animal model using dual-energy absorptiometry is presented in this paper. A radioactive source exciting x-ray fluorescence from a target material is used to provide the two x-ray energies needed. The x-rays, after transmitting through the sample, are measured with an energy-sensitive Ge detector. Phantoms and specimens were measured. The results showed that the method was sensitive to the fat to muscle ratios with good linearity. A standard deviation of a few percent in the fat to muscle ratio could be observed with the x-ray dose of 0.001 mGy.
Fat to Muscle Ratio Measurements with Dual Energy X Ray Absorbtiometry
Chen, A; Broadbent, C; Zhong, J; Dilmanian, A; Zafonte, F; Zhong, Z
2014-01-01
Accurate measurement of the fat-to-muscle ratio in animal model is important for obesity research. An efficient way to measure the fat to muscle ratio in animal model using dual-energy absorptiometry is presented in this paper. A radioactive source exciting x-ray fluorescence from a target material is used to provide the two x-ray energies needed. The x-rays, after transmitting through the sample, are measured with an energy-sensitive Ge detector. Phantoms and specimens were measured. The results showed that the method was sensitive to the fat to muscle ratios with good linearity. A standard deviation of a few percent in the fat to muscle ratio could be observed with the x-ray dose of 0.001 mGy.
78 FR 2273 - Canned Tuna Deviating From Identity Standard; Temporary Permit for Market Testing
2013-01-10
... INFORMATION CONTACT: Loretta A. Carey, Center for Food Safety and Applied Nutrition (HFS-820), Food and Drug..., and Cosmetic Act (21 U.S.C. 341). ] The permit covers limited interstate marketing tests of products... panels on the labels of the test products must bear nutrition labeling in accordance with 21 CFR...
Violation of a temporal Bell inequality for single spins in solid by over 50 standard deviations
Waldherr, G; Huelga, S F; Jelezko, F; Wrachtrup, J
2011-01-01
Quantum non-locality has been experimentally investigated by testing different forms of Bell's inequality, yet a loophole-free realization has not been achieved up to now. Much less explored are temporal Bell inequalities, which are not subject to the locality assumption, but impose a constrain on the system's time-correlations. In this paper, we report on the experimental violation of a temporal Bell's inequality using a nitrogen vacancy defect (NV) in diamond and provide a novel quantitative test of quantum coherence. We therefore present a new technique to initialize the electronic state of the NV with high fidelity, a necessary requirement for reliable quantum information processing and/or the implementation of protocols for quantum metrology.
7 CFR 1724.52 - Permitted deviations from RUS construction standards.
2010-01-01
... may not have the extra measure of protection needed in areas frequented by eagles and other large...) and 1 CFR part 51. Copies of this publication may be obtained from the Raptor Research Foundation, Inc... Division, 1400 Independence Avenue, SW., Washington, DC, Room 1246-S, and at the National Archives...
Rating Slam Dunks to Visualize the Mean, Median, Mode, Range, and Standard Deviation
Robinson, Nick W.; Castle Bell, Gina
2014-01-01
Among the many difficulties beleaguering the communication research methods instructor is the problem of contextualizing abstract ideas. Comprehension of variable operationalization, the utility of the measures of central tendency, measures of dispersion, and the visual distribution of data sets are difficult, since students have not handled data.…
Endong, Floribert Patrick Calvain
2015-01-01
This paper presents the content analysis of randomly selected print advertising copies partially written in Nigerian Pidgin English (NPE), and used for the promotion of services and products made in Nigeria. It is equally based on a focus group discussion with 15 literate and semi literate users (readers) of these copies. It attempts to show how the writing of advertising copy is complex due to the prevalence of different and personalized spelling systems in the representation of NPE words. I...
Doppler standard deviation imaging for clinical monitoring of in vivo human skin blood flow
Zhao, Yonghua; Chen, Zhongping; Saxer, Christopher; Shen, Qimin; Xiang, Shaohua; Boer, Johannes F. de; Nelson, J. Stuart
2000-09-15
We used a novel phase-resolved optical Doppler tomographic (ODT) technique with very high flow-velocity sensitivity (10 {mu}m/s) and high spatial resolution (10 {mu}m) to image blood flow in port-wine stain (PWS) birthmarks in human skin. In addition to the regular ODT velocity and structural images, we use the variance of blood flow velocity to map the PWS vessels. Our device combines ODT and therapeutic systems such that PWS blood flow can be monitored in situ before and after laser treatment. To the authors' knowledge this is the first clinical application of ODT to provide a fast semiquantitative evaluation of the efficacy of PWS laser therapy in situ and in real time. (c) 2000 Optical Society of America.
Dynamic deviation Volterra predistorter designed for linearizing power amplifiers
2011-01-01
Polynomial models of predistorter combined by the "black box" principle have been considered. A Volterra model using one-dimensional dynamic deviation was proposed. An adaptive predistorter was synthesized for linearizing the Wiener–Hammerstein model of power amplifiers. Estimates of the linearization accuracy and a comparative analysis of predistorter models were also presented.
A Positional Deviation Sensor for Training of Robots
Fredrik Dessen
1988-04-01
Full Text Available A device for physically guiding a robot manipulator through its task is described. It consists of inductive, contact-free positional deviation sensors. The sensor will be used in high performance sensory control systems. The paper describes problems concerning multi-dimensional, non-linear measurement functions and the design of the servo control system.
Large Deviation for Supercritical Branching Processes with Immigration
Jing Ning LIU; Mei ZHANG
2016-01-01
In this paper, we study the large deviation for a supercritical branching process with immigration controlled by a sequence of non-negative integer-valued independently identical distributed random variables, improving the previous results for non immigration processes. We rely heavily on the detail description and limit property of the generating function of immigration processes.
9 CFR 381.308 - Deviations in processing.
2010-01-01
... AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY...) must be handled according to: (1)(i) A HACCP plan for canned product that addresses hazards associated... (d) of this section. (c) (d) Procedures for handling process deviations where the HACCP plan...
Current Large Deviations for Asymmetric Exclusion Processes with Open Boundaries
Bodineau, T.; Derrida, B.
2006-04-01
We study the large deviation functional of the current for the Weakly Asymmetric Simple Exclusion Process in contact with two reservoirs. We compare this functional in the large drift limit to the one of the Totally Asymmetric Simple Exclusion Process, in particular to the Jensen-Varadhan functional. Conjectures for generalizing the Jensen-Varadhan functional to open systems are also stated.
48 CFR 2901.403 - Individual deviations from the FAR.
2010-10-01
... the FAR. 2901.403 Section 2901.403 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL DEPARTMENT OF LABOR ACQUISITION REGULATION SYSTEM Deviations From the FAR and DOLAR 2901.403 Individual... provisions (see FAR 1.403) or DOLAR provisions, which affect only one contracting action, unless FAR...
Freidlin-Wentzell's Large Deviations for Stochastic Evolution Equations
Ren, Jiagang; Zhang, Xicheng
2008-01-01
We prove a Freidlin-Wentzell large deviation principle for general stochastic evolution equations with small perturbation multiplicative noises. In particular, our general result can be used to deal with a large class of quasi linear stochastic partial differential equations, such as stochastic porous medium equations and stochastic reaction diffusion equations with polynomial growth zero order term and $p$-Laplacian second order term.
Process Measurement Deviation Analysis for Flow Rate due to Miscalibration
Oh, Eunsuk; Kim, Byung Rae; Jeong, Seog Hwan; Choi, Ji Hye; Shin, Yong Chul; Yun, Jae Hee [KEPCO Engineering and Construction Co., Deajeon (Korea, Republic of)
2016-10-15
An analysis was initiated to identify the root cause, and the exemption of high static line pressure correction to differential pressure (DP) transmitters was one of the major deviation factors. Also the miscalibrated DP transmitter range was identified as another major deviation factor. This paper presents considerations to be incorporated in the process flow measurement instrumentation calibration and the analysis results identified that the DP flow transmitter electrical output decreased by 3%. Thereafter, flow rate indication decreased by 1.9% resulting from the high static line pressure correction exemption and measurement range miscalibration. After re-calibration, the flow rate indication increased by 1.9%, which is consistent with the analysis result. This paper presents the brief calibration procedures for Rosemount DP flow transmitter, and analyzes possible three cases of measurement deviation including error and cause. Generally, the DP transmitter is required to be calibrated with precise process input range according to the calibration procedure provided for specific DP transmitter. Especially, in case of the DP transmitter installed in high static line pressure, it is important to correct the high static line pressure effect to avoid the inherent systematic error for Rosemount DP transmitter. Otherwise, failure to notice the correction may lead to indicating deviation from actual value.
Vertex deviation maps to bracked the Milky Way resonant radius
Roca-Fàbrega, S.; Antoja, T.; Figueras, F.; Valenzuela, O.; Romero-Gómez, M.; Pichardo, B.
2015-05-01
We map the kinematics of stars in simulated galaxy disks with spiral arms using the velocity ellipsoid vertex deviation (l_v). We use test particle simulations, and for the first time, fully self-consistent high resolution N-body models. We compare our maps with the Tight Winding Approximation model analytical predictions. We see that for all barred models spiral arms rotate closely to a rigid body manner and the vertex deviation values correlate with the density peaks position bounded by overdense and underdense regions. In such cases, vertex deviation sign changes from negative to positive when crossing the spiral arms in the direction of disk rotation, in regions where the spiral arms are in between corotation (CR) and the Outer Lindblad Resonance (OLR). By contrast, when the arm sections are inside the CR and outside the OLR, l_v changes from negative to positive.We propose that measurements of the vertex deviations pattern can be used to trace the position of the main resonances of the spiral arms. We propose that this technique might exploit future data from Gaia and APOGEE surveys. For unbarred N-body simulations with spiral arms corotating with disk material at all radii, our analysis suggests that no clear correlation exists between l_v and density structures.
Optical vibration and deviation measurement of rotating machine parts
无
2008-01-01
It is of interest to get appropriate information about the dynamic behaviour of rotating machinery parts in service. This paper presents an approach of optical vibration and deviation measurement of such parts. Essential of this method is an image derotator combined with a high speed camera or a laser doppler vibrometer (LDV).
The one-shot deviation principle for sequential rationality
Hendon, Ebbe; Whitta-Jacobsen, Hans Jørgen; Sloth, Birgitte
1996-01-01
We present a decentralization result which is useful for practical and theoretical work with sequential equilibrium, perfect Bayesian equilibrium, and related equilibrium concepts for extensive form games. A weak consistency condition is sufficient to obtain an analogy to the well known One-Stage......-Stage-Deviation Principle for subgame perfect equilibrium...
An experimental study of credible deviations and ACDC
de Groot Ruiz, A.; Offerman, T.; Onderstal, S.
2011-01-01
We test the Average Credible Deviation Criterion (ACDC), a stability measure and refinement for cheap talk equilibria introduced in De Groot Ruiz, Offerman & Onderstal (2011b). ACDC has been shown to be predictive under general conditions and to organize data well in previous experiments meant to te
International asset pricing under segmentation and PPP deviations
Chaieb, I.; Errunza, V.
2007-01-01
We analyze the impact of both purchasing power parity (PPP) deviations and market segmentation on asset pricing and investor's portfolio holdings. The freely traded securities command a world market risk premium and an inflation risk premium. The securities that can be held by only a subset of
Dispersion in Rectangular Networks: Effective Diffusivity and Large-Deviation Rate Function
Tzella, Alexandra; Vanneste, Jacques
2016-09-01
The dispersion of a diffusive scalar in a fluid flowing through a network has many applications including to biological flows, porous media, water supply, and urban pollution. Motivated by this, we develop a large-deviation theory that predicts the evolution of the concentration of a scalar released in a rectangular network in the limit of large time t ≫1 . This theory provides an approximation for the concentration that remains valid for large distances from the center of mass, specifically for distances up to O (t ) and thus much beyond the O (t1 /2) range where a standard Gaussian approximation holds. A byproduct of the approach is a closed-form expression for the effective diffusivity tensor that governs this Gaussian approximation. Monte Carlo simulations of Brownian particles confirm the large-deviation results and demonstrate their effectiveness in describing the scalar distribution when t is only moderately large.
MUSiC - A Generic Search for Deviations from Monte Carlo Predictions in CMS
Hof, Carsten
2009-05-01
We present a model independent analysis approach, systematically scanning the data for deviations from the Standard Model Monte Carlo expectation. Such an analysis can contribute to the understanding of the CMS detector and the tuning of the event generators. Furthermore, due to the minimal theoretical bias this approach is sensitive to a variety of models of new physics, including those not yet thought of. Events are classified into event classes according to their particle content (muons, electrons, photons, jets and missing transverse energy). A broad scan of various distributions is performed, identifying significant deviations from the Monte Carlo simulation. We outline the importance of systematic uncertainties, which are taken into account rigorously within the algorithm. Possible detector effects and generator issues, as well as models involving supersymmetry and new heavy gauge bosons have been used as an input to the search algorithm.
Comparison of setup deviations for two thermoplastic immobilization masks in glottis cancer
Jung, Jae Hong [Dept. of Biomedical Engineering, College of Medicine, The Catholic University, Seoul (Korea, Republic of)
2017-03-15
The purpose of this study was compare to the patient setup deviation of two different type thermoplastic immobilization masks for glottis cancer in the intensity-modulated radiation therapy (IMRT). A total of 16 glottis cancer cases were divided into two groups based on applied mask type: standard or alternative group. The mean error (M), three-dimensional setup displacement error (3D-error), systematic error (Σ), random error (σ) were calculated for each group, and also analyzed setup margin (mm). The 3D-errors were 5.2 ± 1.3 mm and 5.9 ± 0.7 mm for the standard and alternative groups, respectively; the alternative group was 13.6% higher than the standard group. The systematic errors in the roll angle and the x, y, z directions were 0.8°, 1.7 mm, 1.0 mm, and 1.5 mm in the alternative group and 0.8°, 1.1 mm, 1.8 mm, and 2.0 mm in the alternative group. The random errors in the x, y, z directions were 10.9%, 1.7%, and 23.1% lower in the alternative group than in the standard group. However, absolute rotational angle (i.e., roll) in the alternative group was 12.4% higher than in the standard group. For calculated setup margin, the alternative group in x direction was 31.8% lower than in standard group. In contrast, the y and z direction were 52.6% and 21.6% higher than in the standard group. Although using a modified thermoplastic immobilization mask could be affect patient setup deviation in terms of numerical results, various point of view for an immobilization masks has need to research in terms of clinic issue.
The Laplace Likelihood Ratio Test for Heteroscedasticity
J. Martin van Zyl
2011-01-01
Full Text Available It is shown that the likelihood ratio test for heteroscedasticity, assuming the Laplace distribution, gives good results for Gaussian and fat-tailed data. The likelihood ratio test, assuming normality, is very sensitive to any deviation from normality, especially when the observations are from a distribution with fat tails. Such a likelihood test can also be used as a robust test for a constant variance in residuals or a time series if the data is partitioned into groups.
Bonaccio, Marialaura; Di Castelnuovo, Augusto; Rago, Livia; de Curtis, Amalia; Assanelli, Deodato; Badilini, Fabio; Vaglio, Martino; Costanzo, Simona; Persichillo, Mariarosaria; Cerletti, Chiara; Donati, Maria Benedetta; de Gaetano, Giovanni; Iacoviello, Licia
2015-11-25
T-wave axis deviation (TDev) may help identifying subjects at risk for major cardiac events and mortality, but the pathogenesis of TDev is not well established; in particular, the possible association between TDev and inflammation is unexplored and unknown. We aimed at investigating the association between low-grade inflammation and TDev abnormalities by conducting a cross-sectional analysis on 17,507 subjects apparently free from coronary heart and haematological diseases enrolled in the MOLI-SANI study. TDev was measured from a standard 12-lead resting electrocardiogram. High sensitivity (Hs) C-reactive protein (CRP), leukocyte (WBC) and platelet counts, neutrophil or granulocyte to lymphocyte ratios were used as markers of inflammation. In multivariable model subjects reporting high CRP levels had higher odds of having borderline and abnormal TDev (OR=1.70; 95 %CI: 1.53-1.90 and OR=1.72; 95 %CI: 1.23-2.41, respectively); the association was still significant, although reduced, after controlling for body mass index (OR=1.17; 95 %CI: 1.05-1.32, for borderline and OR=1.46; 95 %CI: 1.03-2.08, for abnormal). Similarly, higher neutrophil or granulocyte to lymphocyte ratios were associated with increased odds of having abnormal TDev. Neither platelet nor leukocyte counts were associated with abnormal TDev. The relationship between CRP with TDev abnormalities was significantly stronger in men, in non- obese or normotensive individuals, and in those without metabolic syndrome. In conclusion, C-reactive protein and some cellular biomarkers of inflammation such as granulocyte or neutrophil to lymphocyte ratios were independently associated with abnormal TDev, especially in subjects at low CVD risk. These results suggest that a low-grade inflammation likely contributes to the pathogenesis of T- wave axis deviation.
Deviation from the superparamagnetic behaviour of fine-particle systems
Malaescu, I
2000-01-01
Studies concerning superparamagnetic behaviour of fine magnetic particle systems were performed using static and radiofrequency measurements, in the range 1-60 MHz. The samples were: a ferrofluid with magnetite particles dispersed in kerosene (sample A), magnetite powder (sample B) and the same magnetite powder dispersed in a polymer (sample C). Radiofrequency measurements indicated a maximum in the imaginary part of the complex magnetic susceptibility, for each of the samples, at frequencies with the magnitude order of tens of MHz, the origin of which was assigned to Neel-type relaxation processes. The static measurements showed a Langevin-type dependence of magnetisation M and of susceptibility chi, on the magnetic field for sample A. For samples B and C deviations from this type of dependence were found. These deviations were analysed qualitatively and explained in terms of the interparticle interactions, dispersion medium influence and surface effects.
Geodesics and Geodesic Deviation for Impulsive Gravitational Waves
Steinbauer, R
1998-01-01
The geometry of impulsive pp-waves is explored via the analysis of the geodesic and geodesic deviation equation using the distributional form of the metric. The geodesic equation involves formally ill-defined products of distributions due to the nonlinearity of the equations and the presence of the Dirac delta distribution. Thus, strictly speaking, it cannot be treated within Schwartz's linear theory of distributions. To cope with this problem we proceed by first regularizing the delta singularity, then solving the regularized equation within classical smooth functions and, finally, obtaining a distributional, regularization-idependent limit as solution to the original problem. We also treat the Jacobi equation which, despite being linear in the deviation vector field, involves even more delicate singular expressions, like the ``square'' of the delta distribution. Again the same regularization procedure provides us with a perfectly well behaved smooth regularization and a regularization-independent distributi...
Deviations in delineated GTV caused by artefacts in 4DCT
Persson, Gitte Fredberg; Nygaard, Ditte Eklund; Brink, Carsten;
2010-01-01
BACKGROUND AND PURPOSE: Four-dimensional computed tomography (4DCT) is used for breathing-adapted radiotherapy planning. Irregular breathing, large tumour motion or interpolation of images can cause artefacts in the 4DCT. This study evaluates the impact of artefacts on gross tumour volume (GTV......) size. MATERIAL AND METHODS: In 19 4DCT scans of patients with peripheral lung tumours, GTV was delineated in all bins. Variations in GTV size between bins in each 4DCT scan were analysed and correlated to tumour motion and variations in breathing signal amplitude and breathing signal period. End......-expiration GTV size (GTVexp) was considered as reference for GTV size. Intra-session delineation error was estimated by re-delineation of GTV in eight of the 4DCT scans. RESULTS: In 16 of the 4DCT scans the maximum deviations from GTVexp were larger than could be explained by delineation error. The deviations...
Large Deviations for the Macroscopic Motion of an Interface
Birmpa, P.; Dirr, N.; Tsagkarogiannis, D.
2017-03-01
We study the most probable way an interface moves on a macroscopic scale from an initial to a final position within a fixed time in the context of large deviations for a stochastic microscopic lattice system of Ising spins with Kac interaction evolving in time according to Glauber (non-conservative) dynamics. Such interfaces separate two stable phases of a ferromagnetic system and in the macroscopic scale are represented by sharp transitions. We derive quantitative estimates for the upper and the lower bound of the cost functional that penalizes all possible deviations and obtain explicit error terms which are valid also in the macroscopic scale. Furthermore, using the result of a companion paper about the minimizers of this cost functional for the macroscopic motion of the interface in a fixed time, we prove that the probability of such events can concentrate on nucleations should the transition happen fast enough.
Magnetic Elements at Finite Temperature and Large Deviation Theory
Kohn, R. V.; Reznikoff, M. G.; vanden-Eijnden, E.
2005-08-01
We investigate thermally activated phenomena in micromagnetics using large deviation theory and concepts from stochastic resonance. We give a natural mathematical definition of finite-temperature astroids, finite-temperature hysteresis loops, etc. Generically, these objects emerge when the (generalized) Arrhenius timescale governing the thermally activated barrier crossing event of magnetic switching matches the timescale at which the magnetic element is pulsed or ramped by an external field; in the special and physically relevant case of multiple-pulse experiments, on the other hand, short-time switching can lead to non-Arrhenius behavior. We show how large deviation theory can be used to explain some properties of the astroids, like their shrinking and sharpening as the number of applied pulses is increased. We also investigate the influence of the dynamics, in particular the relative importance of the gyromagnetic and the damping terms. Finally, we discuss some issues and open questions regarding spatially nonuniform magnetization.
Distributed Detection over Time Varying Networks: Large Deviations Analysis
Bajovic, Dragana; Xavier, Joao; Sinopoli, Bruno; Moura, Jose M F
2010-01-01
We apply large deviations theory to study asymptotic performance of running consensus distributed detection in sensor networks. Running consensus is a stochastic approximation type algorithm, recently proposed. At each time step k, the state at each sensor is updated by a local averaging of the sensor's own state and the states of its neighbors (consensus) and by accounting for the new observations (innovation). We assume Gaussian, spatially correlated observations. We allow the underlying network be time varying, provided that the graph that collects the union of links that are online at least once over a finite time window is connected. This paper shows through large deviations that, under stated assumptions on the network connectivity and sensors' observations, the running consensus detection asymptotically approaches in performance the optimal centralized detection. That is, the Bayes probability of detection error (with the running consensus detector) decays exponentially to zero as k goes to infinity at...
Contiguous Uniform Deviation for Multiple Linear Regression in Pattern Recognition
Andriana, A. S.; Prihatmanto, D.; Hidaya, E. M. I.; Supriana, I.; Machbub, C.
2017-01-01
Understanding images by recognizing its objects is still a challenging task. Face elements detection has been developed by researchers but not yet shows enough information (low resolution in information) needed for recognizing objects. Available face recognition methods still have error in classification and need a huge amount of examples which may still be incomplete. Another approach which is still rare in understanding images uses pattern structures or syntactic grammars describing shape detail features. Image pixel values are also processed as signal patterns which are approximated by mathematical function curve fitting. This paper attempts to add contiguous uniform deviation method to curve fitting algorithm to increase applicability in image recognition system related to object movement. The combination of multiple linear regression and contiguous uniform deviation method are applied to the function of image pixel values, and show results in higher resolution (more information) of visual object detail description in object movement.
Observable Deviations from Homogeneity in an Inhomogeneous Universe
Giblin, John T; Starkman, Glenn D
2016-01-01
How does inhomogeneity affect our interpretation of cosmological observations? It has long been wondered to what extent the observable properties of an inhomogeneous universe differ from those of a corresponding Friedman-Lemaitre-Robertson-Walker (FLRW) model, and how the inhomogeneities affect that correspondence. Here, we use numerical relativity to study the behavior of light beams traversing an inhomogeneous universe and construct the resulting Hubble diagrams. The universe that emerges exhibits an average FLRW behavior, but inhomogeneous structures contribute to deviations in observables across the observer's sky. We also investigate the relationship between angular diameter distance and the angular extent of a source, finding deviations that grow with source redshift. These departures from FLRW are important path-dependent effects with implications for using real observables in an inhomogeneous universe such as our own.
Large Deviation Principle for Benedicks-Carleson Quadratic Maps
Chung, Yong Moo; Takahasi, Hiroki
2012-11-01
Since the pioneering works of Jakobson and Benedicks & Carleson and others, it has been known that a positive measure set of quadratic maps admit invariant probability measures absolutely continuous with respect to Lebesgue. These measures allow one to statistically predict the asymptotic fate of Lebesgue almost every initial condition. Estimating fluctuations of empirical distributions before they settle to equilibrium requires a fairly good control over large parts of the phase space. We use the sub-exponential slow recurrence condition of Benedicks & Carleson to build induced Markov maps of arbitrarily small scale and associated towers, to which the absolutely continuous measures can be lifted. These various lifts together enable us to obtain a control of recurrence that is sufficient to establish a level 2 large deviation principle, for the absolutely continuous measures. This result encompasses dynamics far from equilibrium, and thus significantly extends presently known local large deviations results for quadratic maps.
Large deviations for stochastic flows and their applications
GAO; Fuqing(
2001-01-01
［1］Yoshida, N., A large deviation principle for (r,p)-capacities on the Wiener space, Proba. Th. Rel. Fields, 1993, 94:473-488.［2］Gao, F. Q., Large deviations of (r,p)-capacities for diffusion processes, Advances in Math. (in Chinese), 1996, 25:500-509.［3］Millet, A., Nualart, D., Sanz, M., Large deviations for a class of anticipating stochastic differential equations, Ann.Prob.. 1993, 20: 1902-1931.［4］Millet, A., Nualart, D., Sans, M., Composition of large deviation principles and applications, in Stochastic Analysis (ed.Mayer, E. ), San Diego: Academic Press, 1991, 383-395.［5］Ocone, D., Pardoux, E., A generalized Ito-Ventzell formula, Applications to a class of anticipating stochastic differentialequations, Ann. Inst. Poincaré, Sect. B, 1989, 25: 39-71.［6］Malliavin, P., Nualart, D., Quasi sure analysis of stochastic flows and Banach space valued smooth functionals on the Wiener space, J. Funct. Anal., 1993, 112: 287-317.［7］Huang, Z., Ren, J. , Quasi sure stochastic flows, Stoch. Stoch. Rep. , 1990, 33: 149-157.［8］Gao, E. Q., Large deviations for diffusion processes in Hslder norm, Advances in Math. (in Chinese), 1997, 26: 147-158.［9］Arous, B. G. , Ledoux, M., Grandes déviations sur la déviations de Freidlin-Wentzell en norme holderienne, 1994, Lecr.Notes in Math. , 1994, 987: 1583.［10］Baldi, P. , Sanz, M. , Une remarque sur la théorie des grandes deviations, Lect. Notes Math., 1991, 1485: 345-348.［11］Airault, H., Malliavin, P., Intégration géometrique sur l'espace de Wiener, Bull. Sci. Math., 1988, 112: 3-52.［12］Ikeda, N. , Watanabe, S., Stochastic Differential Equations and Diffusion Processes, 2nd ed., Amsterdam-Kodansha-Tokyo:North-Holland, 1988.［13］Malliavin, P., Stochastic Analysis, Grundlehren der Mathematischen Wissenschaften 313, Berlin: Springer-Verlag, 1997.［14］Brzezniak, Z., Elworthy, K. D., Stochastic flows of diffeomorphism. In Stochastic Analysis and Applications (eds. Davies,I. M.. Truman
Position of the patella in adults in central India: evaluation of the Insall-Salvati ratio.
Upadhyay, Sachin; Raza, H K T; Srivastava, Pranay
2013-04-01
To assess the Insall-Salvati ratio in normal Indian adults to determine its applicability and the incidence of patella alta and baja in Indian populations. 800 knees in 200 men and 200 women aged 18 to 50 (mean, 30) years were evaluated using lateral radiographs. The knee was set in semi-flexion (30º) to enable good visualisation of the patellar tendon and its insertion into the tibia on radiographs. The length of the patellar tendon (LT) over the length of the patella (LP)-the Insall-Salvati ratio-was measured, using a vernier caliper. The mean LT/LP ratio was 1.14 (standard deviation, 0.18). Based on the 95% confidence interval, the ratio was considered normal if within ±40%. The LT/LP ratio was significantly higher in females than males (1.17 vs. 1.12, ppatella alta was significantly greater in our Indian subjects than in western subjects (>1.5 vs. >1.2, ppatella alta (ratio, >1.5) and patella baja (ratio, <0.7) were 2.8% and 1%, respectively. The use of the Insall-Salvati ratio to determine the patellar position is less applicable to Indian populations in which squatting, sitting cross-legged, and kneeling are customs. We propose that the normal range of the ratio for squatters among Indian populations be 0.7 to 1.5.
Moderate deviations for the eigenvalue counting function of Wigner matrices
Doering, Hanna
2011-01-01
We establish a moderate deviation principle (MDP) for the number of eigenvalues of a Wigner matrix in an interval. The proof relies on fine asymptotics of the variance of the eigenvalue counting function of GUE matrices due to Gustavsson. The extension to large families of Wigner matrices is based on the Tao and Vu Four Moment Theorem and applies localization results by Erd\\"os, Yau and Yin. Moreover we investigate families of covariance matrices as well.
Maritime Group Motion Analysis: Representation, Learning, Recognition, and Deviation Detection
2017-02-01
Maritime Group Motion Analysis : Representation, Learning, Recognition, and Deviation Detection § Allen Waxman MultiSensor Scientific, LLC...while the authors were employed by, or sub-contractors of, Intelligent Software Solutions, Inc., of Colorado Springs, CO, USA, funded under contract...reading the PDF file of this manuscript.) Abstract - This paper introduces new concepts and methods in the analysis of group motions over extended
OSMOSIS: A CAUSE OF APPARENT DEVIATIONS FROM DARCY'S LAW.
Olsen, Harold W.
1985-01-01
This review of the existing evidence shows that osmosis causes intercepts in flow rate versus hydraulic gradient relationships that are consistent with the observed deviations from Darcy's law at very low gradients. Moreover, it is suggested that a natural cause of osmosis in laboratory samples could be chemical reactions such as those involved in aging effects. This hypothesis is analogous to the previously proposed occurrence of electroosmosis in nature generated by geochemical weathering reactions. Refs.
Large Deviation Functional of the Weakly Asymmetric Exclusion Process
Enaud, C.; Derrida, B.
2004-02-01
We obtain the large deviation functional of a density profile for the asymmetric exclusion process of L sites with open boundary conditions when the asymmetry scales like 1/L. We recover as limiting cases the expressions derived recently for the symmetric (SSEP) and the asymmetric (ASEP) cases. In the ASEP limit, the non linear differential equation one needs to solve can be analysed by a method which resembles the WKB method.
Probing the deviation from maximal mixing of atmospheric neutrinos
Choubey, S; Choubey, Sandhya; Roy, Probir
2006-01-01
Pioneering atmospheric muon neutrino experiments have demonstrated the near-maximal magnitude of the flavor mixing angle $\\theta_{23}$. But the precise value of the deviation $D \\equiv 1/2 - \\sin^2 \\theta_{23}$ from maximality (if nonzero) needs to be known, being of great interest -- especially to builders of neutrino mass and mixing models. We quantitatively investigate in a three generation framework the feasibility of determining $D$ in a statistically significant manner from studies of the atmospheric $\
Predictive visual tracking based on least absolute deviation estimation
Rongtai Cai; Yanjie Wang
2008-01-01
To cope with the occlusion and intersection between targets and the environment, location prediction is employed in the visual tracking system. Target trace is fitted by sliding subsection polynomials based on least absolute deviation (LAD) estimation, and the future location of target is predicted with the fitted trace. Experiment results show that the proposed location prediction algorithm based on LAD estimation has significant robustness advantages over least square (LS) estimation, and it is more effective than LS-based methods in visual tracking.
D/H Isotope Ratio Measurements of Atmospheric Volatile Organic Compounds
Meisehen, Thomas; Bühler, Fred; Koppmann, Ralf; Krebsbach, Marc
2015-04-01
Analysis of isotope ratios in atmospheric volatile organic compounds (VOC) is a reliable method to allocate their sources, to estimate atmospheric residence times and investigate physical and chemical processes on various temporal and spatial scales. Most investigations yet focus on carbon isotope ratios. Certainly more detailed information can be gained by the ratio of deuterium (D) to hydrogen (H) in VOC, especially due to the high mass ratio. Combining measurements of carbon and hydrogen isotopes could lead to considerable improvement in our understanding of atmospheric processes. For this purpose we set up and thoroughly characterised a gas chromatograph pyrolysis isotope ratio mass spectrometer to measure the D/H ratio in atmospheric VOC. From a custom-made gas standard mixture VOC were adsorbed on Tenax®TA which has the advantage that CO2 is not preconcentrated when measuring ambient air samples. Our results show that the pyrolysis method has significant impact on the D/H ratios. A pyrolysis temperature of at least 1723 K and conditioning of the ceramic tube on a regular basis is essential to obtain reproducible D/H isotope ratios. For an independent comparison D/H ratios of the pure VOC used in the gas standard were determined using elemental analysis by Agroisolab (Jülich, Germany). Comparisons of 10 VOC show perfect agreement within the standard deviations of our measurements and the errors given by Agroisolab, e.g. for n-pentane, toluene, 4-methyl-2-pentanone and n-octane. A slight mean difference of 5.1 o was obtained for n-heptane while significant mean differences of 15.5 o and 20.3 o arose for 1,2,4-trimethylbenzene and isoprene, respectively. We further demonstrate the stability of our system and show that the sample preparation does not affect the isotope ratios. Moreover the applicability of our system to ambient air samples is demonstrated.
Geometric deviation modeling by kinematic matrix based on Lagrangian coordinate
Liu, Weidong; Hu, Yueming; Liu, Yu; Dai, Wanyi
2015-09-01
Typical representation of dimension and geometric accuracy is limited to the self-representation of dimension and geometric deviation based on geometry variation thinking, yet the interactivity affection of geometric variation and gesture variation of multi-rigid body is not included. In this paper, a kinematic matrix model based on Lagrangian coordinate is introduced, with the purpose of unified model for geometric variation and gesture variation and their interactive and integrated analysis. Kinematic model with joint, local base and movable base is built. The ideal feature of functional geometry is treated as the base body; the fitting feature of functional geometry is treated as the adjacent movable body; the local base of the kinematic model is fixed onto the ideal geometry, and the movable base of the kinematic model is fixed onto the fitting geometry. Furthermore, the geometric deviation is treated as relative location or rotation variation between the movable base and the local base, and it's expressed by the Lagrangian coordinate. Moreover, kinematic matrix based on Lagrangian coordinate for different types of geometry tolerance zones is constructed, and total freedom for each kinematic model is discussed. Finally, the Lagrangian coordinate library, kinematic matrix library for geometric deviation modeling is illustrated, and an example of block and piston fits is introduced. Dimension and geometric tolerances of the shaft and hole fitting feature are constructed by kinematic matrix and Lagrangian coordinate, and the results indicate that the proposed kinematic matrix is capable and robust in dimension and geometric tolerances modeling.
PROBABILISTIC MEASURES FOR INTERESTINGNESS OF DEVIATIONS – A SURVEY
Adnan Masood
2013-03-01
Full Text Available Association rule mining has long being plagued with the problem of finding meaningful, actionable knowledge from the large set of rules. In this age of data deluge with modern computing capabilities, we gather, distribute, and store information in vast amounts from diverse data sources. With such data profusion, the core knowledge discovery problem becomes efficient data retrieval rather than simply finding heaps of information. The most common approach is to employ measures of rule interestingness to filter the results of the association rule generation process. However, study of literature suggests that interestingness is difficult to define quantitatively and can be best summarized as, a record or pattern is interesting if it suggests a change in an established model. Almost twenty years ago, Gregory Piatetsky-Shapiro and Christopher J. Matheus, in their paper, “The Interestingness of Deviations,” argued that deviations should be grouped together in a finding and that the interestingness of a finding is the estimated benefit from a possible action connected to it. Since then, this field has progressed and new data mining techniques have been introduced to address the subjective, objective, and semantic interestingness measures. In this brief survey, we review the current state of literature around interestingness of deviations, i.e. outliers with specific interest around probabilistic measures using Bayesian belief networks.
Quantifying prosthetic gait deviation using simple outcome measures
Kark, Lauren; Odell, Ross; McIntosh, Andrew S; Simmons, Anne
2016-01-01
AIM: To develop a subset of simple outcome measures to quantify prosthetic gait deviation without needing three-dimensional gait analysis (3DGA). METHODS: Eight unilateral, transfemoral amputees and 12 unilateral, transtibial amputees were recruited. Twenty-eight able-bodied controls were recruited. All participants underwent 3DGA, the timed-up-and-go test and the six-minute walk test (6MWT). The lower-limb amputees also completed the Prosthesis Evaluation Questionnaire. Results from 3DGA were summarised using the gait deviation index (GDI), which was subsequently regressed, using stepwise regression, against the other measures. RESULTS: Step-length (SL), self-selected walking speed (SSWS) and the distance walked during the 6MWT (6MWD) were significantly correlated with GDI. The 6MWD was the strongest, single predictor of the GDI, followed by SL and SSWS. The predictive ability of the regression equations were improved following inclusion of self-report data related to mobility and prosthetic utility. CONCLUSION: This study offers a practicable alternative to quantifying kinematic deviation without the need to conduct complete 3DGA. PMID:27335814
Tiago André Fontoura de Melo
2011-10-01
Full Text Available Introduction and objective: This study aimed to analyze the influence of root curvature’s initial position on apical deviation occurrence after oscillatory system preparation. Material and methods: For this purpose, we used twenty simulated root canals with 21 mm length and 30 degree angle, which were divided into two experimental groups according to curvature’s initial position: 8 mm (group A and 12 mm (group B short of the canal orifice. The canals were prepared using crown-down technique, and memory instrument was size #30. For apical deviation analysis, before and after preparation, canals were filled with Indian ink and standardly photographed with the aid of a platform. After that, the images were manipulated by Adobe Photoshop® software, through superimposing pre- and post-operative images. Deviation occurrence was measured 1 mm short of working length and at the middle of the curvature by using the ruler tool. Data were subjected to analysis of variance (ANOVA with significance level set at 5%. Results: Although group B showed a significantly greater deviation mean than group A, no significant interaction was verified between the analysis site and the experimental group. Conclusion: According to the present data, it could be observed that the smaller the curvature radius, the greater the deviation. Concerning to the analysis site, it could be noted that the area 1 mm short of working length presented a higher deviation than the point at the middle of the curvature.
A study on the deviation aspects of the poem “The Eightieth Stage”
Soghra Salmaninejad Mehrabadi
2016-02-01
's innovation. New expressions are also used in other parts of abnormality in “The Eightieth Stag e” . Stylistic deviation Sometimes, Akhavan uses local and slang words, and words with different songs and music produces deviation as well. This Application is one kind of abnormality. Words such as “han, hey, by the truth, pity, hoome, kope, meydanak and ...” are of this type of abnormality . Ancient deviation One way to break out of the habit of poetry , is attention to ancient words and actions . Archaism is one of the factors affecting the deviation. Archaism deviation helps to make the old sp. According to Leach, the ancient is the survival of the old language in the now. Syntactic factors, type of music and words, are effective in escape from the standard language. ”Sowrat (sharpness, hamgenan (counterparts, parine (last year, pour ( son, pahlaw (champion’’are Words that show Akhavan’s attention to archaism. The ancient pronunciation is another part of his work. Furthermore, use of mythology and allusion have created deviation of this type. Cases such as anagram adjectival compounds, the use of two prepositions for a word, the use of the adjective and noun in the plural form, are signs of archaism in grammar and syntax. He is interested in grammatical elements of Khorasani Style. Most elements of this style used in “The Eightieth Stage” poetry. S emantic deviation Semantic deviation is caused by the imagery . The poet uses frequently literary figures. By this way, he produces new meaning and therefore highlights his poem. Simile, metaphor, personification and irony are the most important examples of this deviation. Apparently the maximum deviation from the norm in this poem is of periodic deviation (ancient or archaism. The second row belongs to the semantic deviation in which metaphor is the most meaningful. The effect of metaphor in this poem is quite well. In general, Poet’s notice to the different deviations is one of his techniques and the key
Venusian highlands - Geoid to topography ratios and their implications
Smrekar, Suzanne E.; Phillips, Roger J.
1991-01-01
Geoid-to-topography ratios (GTRs) are estimated for 12 Venusian highland features to allow comparison with convection calculations and with terrestrial data of oceanic hot spots, swells, and plateaus. The geoid is estimated in the wavenumber domain from the isostatic formula, using the topography and the apparent depths isostatic compensation (ADC) for each region. In the space domain, the GTR is equal to the least squares slope of the linear fit of the geoid to the topograpy. The resulting GTR range is 7-31 m/km, which is much higher than terrestrial oceanic values (-1 to 5 m/km). The features fall into two distinct groups, one with a GTR range of 7-13 m/km, and one with a range of 19-25 m/km. A model for thermal thinning of a 100-km-thick lithosphere fits all values in the lower GTR group to within one standard deviation.
The retest distribution of the visual field summary index mean deviation is close to normal.
Anderson, Andrew J; Cheng, Allan C Y; Lau, Samantha; Le-Pham, Anne; Liu, Victor; Rahman, Farahnaz
2016-09-01
When modelling optimum strategies for how best to determine visual field progression in glaucoma, it is commonly assumed that the summary index mean deviation (MD) is normally distributed on repeated testing. Here we tested whether this assumption is correct. We obtained 42 reliable 24-2 Humphrey Field Analyzer SITA standard visual fields from one eye of each of five healthy young observers, with the first two fields excluded from analysis. Previous work has shown that although MD variability is higher in glaucoma, the shape of the MD distribution is similar to that found in normal visual fields. A Shapiro-Wilks test determined any deviation from normality. Kurtosis values for the distributions were also calculated. Data from each observer passed the Shapiro-Wilks normality test. Bootstrapped 95% confidence intervals for kurtosis encompassed the value for a normal distribution in four of five observers. When examined with quantile-quantile plots, distributions were close to normal and showed no consistent deviations across observers. The retest distribution of MD is not significantly different from normal in healthy observers, and so is likely also normally distributed - or nearly so - in those with glaucoma. Our results increase our confidence in the results of influential modelling studies where a normal distribution for MD was assumed. © 2016 The Authors Ophthalmic & Physiological Optics © 2016 The College of Optometrists.
Cicconetti, P; Salza, M C; Rizzo, V; Bianchi, A; Capponi, L; Marigliano, V
1996-01-01
Antihypertensive drug therapy uniformity of efficacy was evaluated in a group of elderly hypertensive subjects with trough-to-peak ratio, after a period of antihypertensive drug therapy with ACE-inhibitor fosinopril. An ambulatory blood pressure monitoring (ABPM) with evaluation of blood pressure variability assessed by standard deviation (S.D.) and coefficient of variation (C.V.) were evaluated in each subjects. Our preliminary data showed that the treatment with fosinopril had satisfactory uniformity of efficacy during all the 24-hour period, with both full dose (20 mg) and reduced dose (10 mg); little influence on blood pressure variability was determined by antihypertensive treatment.
C Van Der Horst
2003-08-01
Full Text Available PURPOSE: The Schroeder-Essed plication procedure is a standard technique for the correction of penile curvature. In a retrospective analysis we compared functional results and quality of life (LQ of the original technique with inverted sutures as described by Schroeder-Essed and our slight modification consisting of horizontal incisions into the tunica albuginea. MATERIALS AND METHODS: Twenty-six patients with congenital penis deviation were treated for penile deviation by the original Schroeder-Essed plication with inverted sutures (11 patients and by the described modification (15 patients. In case of modified technique, horizontal and parallel incisions 4 mm to 6 mm apart and about 8 mm - 10 mm long were made through the tunica albuginea. The outer edges of the incisions were then approximated with permanent inverted sutures (Gore-Tex® 3-0. Mean age was 21.6 years in the first group and 23.2 years in the second group. Average follow-up was 28 months and 13 months, respectively. The preoperative penile deviation angle was > 25º in all patients without difference between the 2 groups. RESULTS: All patients in both groups reported an improvement in their quality of life and full ability to engage in sexual intercourse. Nine patients (88% in the first group and 14 patients (93% in the second group were satisfied with the cosmetic result. In contrast, 10 patients (91% of the first and 13 patients (87% of the second group complained of penile shorting. Recurrence of deviation was only noticed in 2 males in the first group (18%. CONCLUSIONS: Our results indicate that this simple modification of the Schroeder-Essed plication offers good functional and cosmetic results. Most patients were satisfied with the penile angle correction results.
Beat the Deviations in Estimating Maximum Power of Thermoelectric Modules
Gao, Junling; Chen, Min
2013-01-01
Under a certain temperature difference, the maximum power of a thermoelectric module can be estimated by the open-circuit voltage and the short-circuit current. In practical measurement, there exist two switch modes, either from open to short or from short to open, but the two modes can give...... different estimations on the maximum power. Using TEG-127-2.8-3.5-250 and TEG-127-1.4-1.6-250 as two examples, the difference is about 10%, leading to some deviations with the temperature change. This paper analyzes such differences by means of a nonlinear numerical model of thermoelectricity, and finds out...
Elimination of Nonlinear Deviations in Thermal Lattice BGK Models
Chen, Y; Hongo, T; Chen, Yu; Ohashi, Hirotada; Akiyam, Mamoru
1993-01-01
Abstracet: We present a new thermal lattice BGK model in D-dimensional space for the numerical calculation of fluid dynamics. This model uses a higher order expansion of equilibrium distribution in Maxwellian type. In the mean time the lattice symmetry is upgraded to ensure the isotropy of 6th order tensor. These manipulations lead to macroscopic equations free from nonlinear deviations. We demonstrate the improvements by conducting classical Chapman-Enskog analysis and by numerical simulation of shear wave flow. The transport coefficients are measured numerically, too.
Brief Analysis of the Semantic Deviation in Oliver Twist
黄二靓
2016-01-01
As one of the foremost critical realist writers of the Victorian era, Charles Dickens is adept at using language to create all kinds of characters in a humorous or ironic tone. Therefore he received massive popularity for his unique style in storytelling. Oliver Twist is one of Charles Dickens's masterpieces and also the most appropriate choice for the stylistic study on Charles Dickens. This thesis endeavors to explore the aesthetic effect of semantic deviation appearing in Oliver Twist so that we can have a better comprehension about the excellent writing skill of Charles Dickens.
Quenched Large Deviations for Interacting Diffusions in Random Media
Luçon, Eric
2017-03-01
The aim of the paper is to establish a large deviation principle (LDP) for the empirical measure of mean-field interacting diffusions in a random environment. The point is to derive such a result once the environment has been frozen (quenched model). The main theorem states that a LDP holds for every sequence of environment satisfying appropriate convergence condition, with a rate function that does not depend on the disorder and is different from the rate function in the averaged model. Similar results concerning the empirical flow and local empirical measures are provided.
Pitch deviation analysis of pathological voice in connected speech.
Laflen, J Brandon; Lazarus, Cathy L; Amin, Milan R
2008-02-01
This study compares normal and pathologic voices using a novel voice analysis algorithm that examines pitch deviation during connected speech. The study evaluates the clinical potential of the algorithm as a mechanism to distinguish between normal and pathologic voices using connected speech. Adult vocalizations from normal subjects and patients with known benign free-edge vocal fold lesions were analyzed. Recordings had been previously obtained in quiet under controlled conditions. Two phrases and sustained /a/ were recorded per subject. The subject populations consisted of 10 normal and 31 abnormal subjects. The voice analysis algorithm generated 2-dimensional patterns that represent pitch deviation in time and under variable window widths. Measures were collected from these patterns for window widths between 10 and 250 ms. For comparison, jitter and shimmer measures were collected from sustained /a/ by means of the Computerized Speech Lab (CSL). A t-test and tests of sensitivity and specificity assessed discrimination between normal and abnormal populations. More than 58% of the measures collected from connected speech outperformed the CSL jitter and shimmer measures in population discrimination. Twenty-five percent of the experimental measures (including /a/) indicated significantly different populations (p connected speech.
Cohen, Mervyn D. [Indiana University School of Medicine, Department of Radiology, Riley Children' s Hospital, Indianapolis, IN (United States); Riley Hospital for Children, Department of Radiology, Indianapolis, IN (United States); Cooper, Matt L.; Piersall, Kelly [Indiana University School of Medicine, Department of Radiology, Riley Children' s Hospital, Indianapolis, IN (United States); Apgar, Bruce K. [Agfa HealthCare Corporation, Greenville, SC (United States)
2011-05-15
Many methods are used to track patient exposure during acquisition of plain film radiographs. A uniform international standard would aid this process. To evaluate and describe a new, simple quality-assurance method for monitoring patient exposure. This method uses the ''exposure index'' and the ''deviation index,'' recently developed by the International Electrotechnical Commission (IEC) and American Association of Physicists in Medicine (AAPM). The deviation index measures variation from an ideal target exposure index value. Our objective was to determine whether the exposure index and the deviation index can be used to monitor and control exposure drift over time. Our Agfa workstation automatically keeps a record of the exposure index for every patient. The exposure index and deviation index were calculated on 1,884 consecutive neonatal chest images. Exposure of a neonatal chest phantom was performed as a control. Acquisition of the exposure index and calculation of the deviation index was easily achieved. The weekly mean exposure index of the phantom and the patients was stable and showed <10% change during the study, indicating no exposure drift during the study period. The exposure index is an excellent tool to monitor the consistency of patient exposures. It does not indicate the exposure value used, but is an index to track compliance with a pre-determined target exposure. (orig.)
Kalman Filtering with Intermittent Observations: Weak Convergence and Moderate Deviations
Kar, Soummya
2009-01-01
The paper considers the problem of Kalman filtering with intermittent observations, where the observation packet arrival process is modeled as a Bernoulli process. We start by extending the results of \\cite{Riccati-weakconv} to show that the sequence of random conditional error covariance matrices converges in distribution to a unique invariant distribution $\\mathbb{\\mu}^{\\bar{\\gamma}}$, as long as the packet arrival probability $\\bar{\\gamma}>0$. We completely characterize the sequence ${\\mathbb{\\mu}^{\\bar{\\gamma}}}$ of invariant distributions as $\\bar{\\gamma}\\uparrow 1$, by showing that the sequence ${\\mathbb{\\mu}^{\\bar{\\gamma}}}$ satisfies a moderate deviations principle (MDP) with a good rate function $I$, which is explicitly characterized. We then study the sequence of invariant distributions ${\\mathbb{\\mu}^{\\bar{\\gamma}}}$ as $\\bar{\\gamma}\\uparrow 1$. We show that, as $\\bar{\\gamma}\\uparrow 1$, ...
Mod-ϕ convergence normality zones and precise deviations
Féray, Valentin; Nikeghbali, Ashkan
2016-01-01
The canonical way to establish the central limit theorem for i.i.d. random variables is to use characteristic functions and Lévy’s continuity theorem. This monograph focuses on this characteristic function approach and presents a renormalization theory called mod-ϕ convergence. This type of convergence is a relatively new concept with many deep ramifications, and has not previously been published in a single accessible volume. The authors construct an extremely flexible framework using this concept in order to study limit theorems and large deviations for a number of probabilistic models related to classical probability, combinatorics, non-commutative random variables, as well as geometric and number-theoretical objects. Intended for researchers in probability theory, the text is carefully well-written and well-structured, containing a great amount of detail and interesting examples. .
Prevalence of voice quality deviations in the normal adult population.
Brindle, B R; Morris, H L
1979-11-01
The purpose of this study was to determine the prevalence of voice quality deviations in a normal adult population. One-hundred twelve subjects, aged 17 to 80, read a short paragraph aloud into a high-fidelity tape recorder and completed a case history questionnaire. A group of 11 pretrained judges rated overall performance of each taped sample on a seven-point equal-appearing intervals scale, then designated those quality components which contributed toward deviant ratings. Eighty-two percent of the group received a mean severity rating lower than 1.99; 16% had a rating between 2.00 and 2.99; and 2% was assigned a mean rating higher than 3.00.
Lyapunov exponents of linear cocycles continuity via large deviations
Duarte, Pedro
2016-01-01
The aim of this monograph is to present a general method of proving continuity of Lyapunov exponents of linear cocycles. The method uses an inductive procedure based on a general, geometric version of the Avalanche Principle. The main assumption required by this method is the availability of appropriate large deviation type estimates for quantities related to the iterates of the base and fiber dynamics associated with the linear cocycle. We establish such estimates for various models of random and quasi-periodic cocycles. Our method has its origins in a paper of M. Goldstein and W. Schlag. Our present work expands upon their approach in both depth and breadth. We conclude this monograph with a list of related open problems, some of which may be treated using a similar approach.
Interpreting spacetimes of any dimension using geodesic deviation
Podolsky, Jiri
2012-01-01
We present a general method which can be used for geometrical and physical interpretation of an arbitrary spacetime in four or any higher number of dimensions. It is based on the systematic analysis of relative motion of free test particles. We demonstrate that local effect of the gravitational field on particles, as described by equation of geodesic deviation with respect to a natural orthonormal frame, can always be decomposed into a canonical set of transverse, longitudinal and Newton-Coulomb-type components, isotropic influence of a cosmological constant, and contributions arising from specific matter content of the universe. In particular, exact gravitational waves in Einstein's theory always exhibit themselves via purely transverse effects with D(D-3)/2 independent polarization states. To illustrate the utility of this approach we study the family of pp-wave spacetimes in higher dimensions and discuss specific measurable effects on a detector located in four spacetime dimensions. For example, the corres...
Geodesic deviation in Kundt spacetimes of any dimension
Svarc, Robert
2012-01-01
Using the invariant form of the equation of geodesic deviation, which describes relative motion of free test particles, we investigate a general family of D-dimensional Kundt spacetimes. We demonstrate that local influence of the gravitational field can be naturally decomposed into Newton-type tidal effects typical for type II spacetimes, longitudinal deformations mainly present in spacetimes of algebraic type III, and type N purely transverse effects corresponding to gravitational waves with D(D-3)/2 independent polarization states. We explicitly study the most important examples, namely exact pp-waves, gyratons, and VSI spacetimes. This analysis helps us to clarify the geometrical and physical interpretation of the Kundt class of nonexpanding, nontwisting and shearfree geometries.
Deviations from Wick's theorem in the canonical ensemble
Schönhammer, K.
2017-07-01
Wick's theorem for the expectation values of products of field operators for a system of noninteracting fermions or bosons plays an important role in the perturbative approach to the quantum many-body problem. A finite-temperature version holds in the framework of the grand canonical ensemble, but not for the canonical ensemble appropriate for systems with fixed particle number such as ultracold quantum gases in optical lattices. Here we present formulas for expectation values of products of field operators in the canonical ensemble using a method in the spirit of Gaudin's proof of Wick's theorem for the grand canonical case. The deviations from Wick's theorem are examined quantitatively for two simple models of noninteracting fermions.
A sella turcica bridge in subjects with severe craniofacial deviations.
Becktor, J P; Einersen, S; Kjaer, I
2000-02-01
In earlier studies, a sella turcica bridge was stated to occur in 1.75 to 6 per cent of the population. The occurrence of a sella turcica bridge has not previously been studied in a group of patients with craniofacial deviations treated by surgery. Profile radiographs from 177 individuals who had undergone combined orthodontic and surgical treatment at the Copenhagen School of Dentistry were studied. A sella turcica bridge was registered in those subjects where the radiograph revealed a continuous band of bony tissue from the anterior cranial fossa to the posterior cranial fossa across the sella turcica. Two types of sella turcica bridge were identified. A sella turcica bridge occurred in 18.6 per cent of the subjects.
Large Deviation Results for Generalized Compound Negative Binomial Risk Models
Fan-chao Kong; Chen Shen
2009-01-01
In this paper we extend and improve some results of the large deviation for random sums of random variables.Let {Xn;n≥1} be a sequence of non-negative,independent and identically distributed random variables with common heavy-tailed distribution function F and finite mean μ∈R+,{N(n);n≥0} be a sequence of negative binomial distributed random variables with a parameter p ∈(0,1),n≥0,let {M(n);n≥0} be a Poisson process with intensity λ0.Suppose {N(n);n≥0},{Xn;n≥1} and {M(n);n≥0} are mutually results.These results can be applied to certain problems in insurance and finance.
Regulation on radial position deviation for vertical AMB systems
Tsai, Nan-Chyuan; Kuo, Chien-Hsien; Lee, Rong-Mao
2007-10-01
As a source of model uncertainty, gyroscopic effect, depending on rotor speed, is studied for the vertical active magnetic bearing (VAMB) systems which are increasingly used in various industries such as clean rooms, compressors and satellites. This research applies H∞ controller to regulate the rotor position deviations of the VAMB systems in four degrees of freedom. The performance of H∞ controller is examined by experimental simulations to inspect its closed-loop stiffness, rise time and capability to suppress the high frequency disturbances. Although the H∞ is inferior to the LQR in position deviation regulation, the required control current in the electromagnetic bearings is much less than that for LQR or PID and the performance robustness is well retained. In order to ensure the stability robustness of H∞ controller, two approaches, by Kharitonov polynomials and TITO (two inputs & two outputs) Nyquist Stability Criterion, are employed to synthesize the control feedback loop. A test rig is built to further verify the efficacy of the proposed H∞ controller experimentally. Two Eddy-current types of gap sensors, perpendicular to each other, are included to the realistic rotor-bearing system. A four-pole magnetic bearing is used as the actuator for generation of control force. The commercial I/O module unit with A/D and D/A converters, dSPACE DS1104, is integrated to the VAMB, gap sensors, power amplifiers and signal processing circuits. The H∞ is designed on the basis of rotor speed 10 K rpm but in fact it is significantly robust with respect to the rotor speed, varying from 6.5 to 13.5 K rpm.
Spine deviations and orthodontic treatment of asymmetric malocclusions in children
Lippold Carsten
2012-08-01
Full Text Available Abstract Background The aim of this randomized clinical trial was to assess the effect of early orthodontic treatment for unilateral posterior cross bite in the late deciduous and early mixed dentition using orthopedic parameters. Methods Early orthodontic treatment was performed by initial maxillary expansion and subsequent activator therapy (Münster treatment concept. The patient sample was initially comprised of 80 patients with unilateral posterior cross bite (mean age 7.3 years, SD 2.1 years. After randomization, 77 children attended the initial examination appointment (therapy = 37, control = 40; 31 children in the therapy group and 35 children in the control group were monitored at the follow-up examination (T2. The mean interval between T1 and T2 was 1.1 years (SD 0.2 years. Rasterstereography was used for back shape analysis at T1 and T2. Using the profile, the kyphotic and lordotic angle, the surface rotation, the lateral deviation, pelvic tilt and pelvic torsion, statistical differences at T1 and T2 between the therapy and control groups were calculated (t-test. Our working hypothesis was, that early orthodontic treatment can induce negative therapeutic changes in body posture through thoracic and lumbar position changes in preadolescents with uniltaral cross bite. Results No clinically relevant differences between the control and the therapy groups at T1 and T2 were found for the parameters of kyphotic and lordotic angle, the surface rotation, lateral deviation, pelvic tilt, and pelvic torsion. Conclusions Our working hypothesis was tested to be not correct (within the limitations of this study. This randomized clinical trial demonstrates that in a juvenile population with unilateral posterior cross bite the selected early orthodontic treatment protocol does not affect negatively the postural parameters. Trial registration DRKS00003497 on DRKS
Deviations in Ukrainian gender culture: social and systemologic aspect
I. O. Svyatnenko
2017-08-01
Full Text Available The article is devoted to the problem of understanding of traditional (internal deviations in Ukrainian gender culture, which are developing rapidly under the influence of the spread of foreign cultures’ (mainly European and American ones gender deviations. As a result of the study, the following conclusion has been made by the author that matriarchy, cultivated by mistrust of men to each other, their mutual demonization due to the idealization of mothers and devaluation of fathers, contributes to the growth of misandry and homophobia of non-sexual content. We are talking about fears associated with non-sexual (socio-cultural and socio-economic spheres, which, however, can sexualize and take the form of sexual homophobia. These fears relate mostly to various manifestations of lies and fraud, which become normal for men’s relationships precisely because of the inferiority of communications between them. It has been stated in the article that mizandry and homophobia in Ukrainian gender culture express the fears of men before the masculine manifestations of themselves in any sphere of activity (including the sexual sphere that are projected onto other men as external objects and cause social and behavioral reactions or other technologies of gender castration (cultural, social, mental or bodily. The society reacts to masculine men with gender repression as their behavior is interpreted by other participants of social interactions as carrying a threat to the developed scenarios of suppression of social aggression. The damage of these scenarios is that any constructive activity causes social feelings of suspicion and envy, which entails centrifugal social reactions in the form of isolation of the initiator of this activity or sabotage and social escapism. This defectiveness manifests itself in the predominant concealment of the motives and intentions of participants and the disparity of verbal behavior with real behavioral characteristics.
Zhou, Jizhong; He, Zhili; Zhou, Jizhong
2008-03-06
Signal-to-noise-ratio (SNR) thresholds for microarray data analysis were experimentally determined with an oligonucleotide array that contained perfect match (PM) and mismatch (MM) probes based upon four genes from Shewanella oneidensis MR-1. A new SNR calculation, called signal to both standard deviations ratio (SSDR) was developed, and evaluated along with other two methods, signal to standard deviation ratio (SSR), and signal to background ratio (SBR). At a low stringency, the thresholds of SSR, SBR, and SSDR were 2.5, 1.60 and 0.80 with oligonucleotide and PCR amplicon as target templates, and 2.0, 1.60 and 0.70 with genomic DNA as target templates. Slightly higher thresholds were obtained at the high stringency condition. The thresholds of SSR and SSDR decreased with an increase in the complexity of targets (e.g., target types), and the presence of background DNA, and a decrease in the composition of targets, while SBR remained unchanged under all situations. The lowest percentage of false positives (FP) and false negatives (FN) was observed with the SSDR calculation method, suggesting that it may be a better SNR calculation for more accurate determination of SNR thresholds. Positive spots identified by SNR thresholds were verified by the Student t-test, and consistent results were observed. This study provides general guidance for users to select appropriate SNR thresholds for different samples under different hybridization conditions.
Pudji Andayani
2006-10-01
Full Text Available This report aimed to assess mothers’ perceptions on normal and deviation of development in their children. The study was done in underfive children and their mothers from May 1st 1999 to June 30th 1999 who visited the Nutrition, Growth & Development Clinic of the Child Health Department, Sanglah Hospital, Denpasar. A total of 76 children between 2 and 59 months of age and their mothers were enrolled. Data were collected by interview with mothers concerning the following items: perception of their children development, age of child, sex, mother’s education, mother’s job, number of sibling, and mother ability in making referral decisions. Denver II screening test was administered to each child to identify of development status as a gold standard. Sixteen (21% children was identified as having developmental deviation (by mother’s perception and 21 (28% by authors using Denver II screening test. The mother’s perception sensitivity was 67% and specificity was 97%. There were no significant differences of development status perception according to child’s age, mother’s education, mother’s job, and number of sibling. Most of mother’s perceptions about normal development were if the body weight increased and had no disability. Most of the sources of information about development was from the relatives. Thirteen of 21 children who had developmental deviation were referred by mothers. We conclude that mother’s perception can be used as early detection of developmental problems. Mother’s concerns of their children growth development had focused on again body weight, physical developmental and gross motor skill.
Kirk, J. T. O.
1967-01-01
A method is described for determination of the base composition (as guanine+cytosine or adenine+thymine content) of DNA by accurate measurement of the adenine/guanine ratio. The DNA is hydrolysed with 0·03n-hydrochloric acid for 40min. to release the purines. The hydrolysate is subjected to ion-exchange chromatography on Zeo-Karb 225. Apurinic acids are eluted with 0·03n-hydrochloric acid and then guanine and adenine are eluted separately with 2n-hydrochloric acid. Guanine and adenine are each collected as a single fraction, and the amount of base in each case is determined by measuring the volume and the extinction at suitable wavelengths. For use in the calculations, millimolar extinction coefficients in 2n-hydrochloric acid of 12·09 for adenine at 262mμ, and 10·77 for guanine at 248mμ, were determined with authentic samples of bases. The method gives extremely reproducible results: from 12 determinations with calf thymus DNA the adenine/guanine molar ratio had a standard deviation of 0·011; this corresponds to a standard deviation in guanine+cytosine content of 0·2% guanine+cytosine. PMID:5626094
Kirk, J T
1967-11-01
A method is described for determination of the base composition (as guanine+cytosine or adenine+thymine content) of DNA by accurate measurement of the adenine/guanine ratio. The DNA is hydrolysed with 0.03n-hydrochloric acid for 40min. to release the purines. The hydrolysate is subjected to ion-exchange chromatography on Zeo-Karb 225. Apurinic acids are eluted with 0.03n-hydrochloric acid and then guanine and adenine are eluted separately with 2n-hydrochloric acid. Guanine and adenine are each collected as a single fraction, and the amount of base in each case is determined by measuring the volume and the extinction at suitable wavelengths. For use in the calculations, millimolar extinction coefficients in 2n-hydrochloric acid of 12.09 for adenine at 262mmu, and 10.77 for guanine at 248mmu, were determined with authentic samples of bases. The method gives extremely reproducible results: from 12 determinations with calf thymus DNA the adenine/guanine molar ratio had a standard deviation of 0.011; this corresponds to a standard deviation in guanine+cytosine content of 0.2% guanine+cytosine.
Amplification biases: possible differences among deviating gene expressions
Piumi Francois
2008-01-01
Full Text Available Abstract Background Gene expression profiling has become a tool of choice to study pathological or developmental questions but in most cases the material is scarce and requires sample amplification. Two main procedures have been used: in vitro transcription (IVT and polymerase chain reaction (PCR, the former known as linear and the latter as exponential. Previous reports identified enzymatic pitfalls in PCR and IVT protocols; however the possible differences between the sequences affected by these amplification defaults were only rarely explored. Results Screening a bovine cDNA array dedicated to embryonic stages with embryonic (n = 3 and somatic tissues (n = 2, we proceeded to moderate amplifications starting from 1 μg of total RNA (global PCR or IVT one round. Whatever the tissue, 16% of the probes were involved in deviating gene expressions due to amplification defaults. These distortions were likely due to the molecular features of the affected sequences (position within a gene, GC content, hairpin number but also to the relative abundance of these transcripts within the tissues. These deviating genes mainly encoded housekeeping genes from physiological or cellular processes (70% and constituted 2 subsets which did not overlap (molecular features, signal intensities, gene ID. However, the differential expressions identified between embryonic stages were both reliable (minor intersect with biased expressions and relevant (biologically validated. In addition, the relative expression levels of those genes were biologically similar between amplified and unamplified samples. Conclusion Conversely to the most recent reports which challenged the use of intense amplification procedures on minute amounts of RNA, we chose moderate PCR and IVT amplifications for our gene profiling study. Conclusively, it appeared that systematic biases arose even with moderate amplification procedures, independently of (i the sample used: brain, ovary or embryos, (ii
JIANG Tao
2008-01-01
We establish an asymptotic relation for the large-deviation probabilities of the maxima of sums of subexponential random variables centered by multiples of order statistics of i.i.d. standard uniform random variables. This extends a corresponding result of Korshunov. As an application, we generalize a result of Tang,the uniform asymptotic estimate for the finite-time ruin probability, to the whole strongly subexponential class.
2008-01-01
We establish an asymptotic relation for the large-deviation probabilities of the maxima of sums of subexponential random variables centered by multiples of order statistics of i.i.d.standard uniform random variables.This extends a corresponding result of Korshunov.As an application,we generalize a result of Tang,the uniform asymptotic estimate for the finite-time ruin probability,to the whole strongly subexponential class.
Salor, Oezguel [TUeBiTAK - Uzay, Power Electronics Group, METU Campus, TR 06531, Ankara (Turkey)
2009-07-15
In this paper, a spectral correction-based algorithm for interharmonic computation is proposed for especially highly fluctuating fundamental frequency cases in the power system. It has been observed and reported that fluctuating demands of some loads such as arc furnaces, or disturbances and subsequent system transients make the fundamental frequency of the power system deviate and this causes non-existing interharmonics to appear in the spectrum due to grid-effect when a standard window length is used for the entire FFT process. The proposed method uses a synthetic waveform produced at the fundamental frequency and amplitude to determine the amount of the leakage due to the grid-effect at each frequency. Then the leakage is subtracted from the original FFT of the signal to correct the frequency spectrum. It has been shown that the leakage effect caused by the fundamental frequency variation is avoided with a correction algorithm applied after FFT and the error in the first interharmonic computation due to frequency deviation is reduced to zero exactly if the fundamental frequency can be determined accurately. Both simulative and field data tests have been performed. The method does not require online sampling frequency or FFT window length adjustment and it is simple to implement. (author)
WKB theory of large deviations in stochastic populations
Assaf, Michael; Meerson, Baruch
2017-06-01
Stochasticity can play an important role in the dynamics of biologically relevant populations. These span a broad range of scales: from intra-cellular populations of molecules to population of cells and then to groups of plants, animals and people. Large deviations in stochastic population dynamics—such as those determining population extinction, fixation or switching between different states—are presently in a focus of attention of statistical physicists. We review recent progress in applying different variants of dissipative WKB approximation (after Wentzel, Kramers and Brillouin) to this class of problems. The WKB approximation allows one to evaluate the mean time and/or probability of population extinction, fixation and switches resulting from either intrinsic (demographic) noise, or a combination of the demographic noise and environmental variations, deterministic or random. We mostly cover well-mixed populations, single and multiple, but also briefly consider populations on heterogeneous networks and spatial populations. The spatial setting also allows one to study large fluctuations of the speed of biological invasions. Finally, we briefly discuss possible directions of future work.
Optimal aggregation of noisy observations: A large deviations approach
Murayama, Tatsuto; Davis, Peter, E-mail: murayama@cslab.kecl.ntt.co.j, E-mail: davis@cslab.kecl.ntt.co.j [NTT Communication Science Laboratories, NTT Corporation, 2-4, Hikaridai, Seika-cho, Keihanna, Kyoto 619-0237 (Japan)
2010-06-01
Sensing and data aggregation tasks in distributed systems should not be considered as separate issues. The quality of collective estimation involves a fundamental tradeoff between sensing quality, which can be increased by increasing the number of sensors, and aggregation quality under a given capacity of the network, which decreases if the number of sensors is too large. In this paper, we examine a system level strategy for optimal aggregation of data from an ensemble of independent sensors. In particular, we consider large scale aggregation from very many sensors, in which case the network capacity diverges to infinity. Then, by applying the large deviations techniques, we conclude the following significant result: larger scale aggregation always outperforms smaller scale aggregation at higher noise levels, while below a critical value of noise, there exist moderate scale aggregation levels at which optimal estimation is realized. At a critical value of noise, there is an abrupt change in the behavior of a parameter characterizing the aggregation strategy, similar to a phase transition in statistical physics.
Gait Deviations in Children with Autism Spectrum Disorders: A Review
Deirdre Kindregan
2015-01-01
Full Text Available In recent years, it has become clear that children with autism spectrum disorders (ASDs have difficulty with gross motor function and coordination, factors which influence gait. Knowledge of gait abnormalities may be useful for assessment and treatment planning. This paper reviews the literature assessing gait deviations in children with ASD. Five online databases were searched using keywords “gait” and “autism,” and 11 studies were found which examined gait in childhood ASD. Children with ASD tend to augment their walking stability with a reduced stride length, increased step width and therefore wider base of support, and increased time in the stance phase. Children with ASD have reduced range of motion at the ankle and knee during gait, with increased hip flexion. Decreased peak hip flexor and ankle plantar flexor moments in children with ASD may imply weakness around these joints, which is further exhibited by a reduction in ground reaction forces at toe-off in children with ASD. Children with ASD have altered gait patterns to healthy controls, widened base of support, and reduced range of motion. Several studies refer to cerebellar and basal ganglia involvement as the patterns described suggest alterations in those areas of the brain. Further research should compare children with ASD to other clinical groups to improve assessment and treatment planning.
Geometry of River Networks; 1, Scaling, Fluctuations, and Deviations
Dodds, P S; Dodds, Peter Sheridan; Rothman, Daniel H.
2000-01-01
This article is the first in a series of three papers investigating the detailed geometry of river networks. Large-scale river networks mark an important class of two-dimensional branching networks, being not only of intrinsic interest but also a pervasive natural phenomenon. In the description of river network structure, scaling laws are uniformly observed. Reported values of scaling exponents vary suggesting that no unique set of scaling exponents exists. To improve this current understanding of scaling in river networks and to provide a fuller description of branching network structure, we report here a theoretical and empirical study of fluctuations about and deviations from scaling. We examine data for continent-scale river networks such as the Mississippi and the Amazon and draw inspiration from a simple model of directed, random networks. We center our investigations on the scaling of the length of sub-basin's dominant stream with its area, a characterization of basin shape known as Hack's law. We gene...
Large deviations of ergodic counting processes: a statistical mechanics approach.
Budini, Adrián A
2011-07-01
The large-deviation method allows to characterize an ergodic counting process in terms of a thermodynamic frame where a free energy function determines the asymptotic nonstationary statistical properties of its fluctuations. Here we study this formalism through a statistical mechanics approach, that is, with an auxiliary counting process that maximizes an entropy function associated with the thermodynamic potential. We show that the realizations of this auxiliary process can be obtained after applying a conditional measurement scheme to the original ones, providing is this way an alternative measurement interpretation of the thermodynamic approach. General results are obtained for renewal counting processes, that is, those where the time intervals between consecutive events are independent and defined by a unique waiting time distribution. The underlying statistical mechanics is controlled by the same waiting time distribution, rescaled by an exponential decay measured by the free energy function. A scale invariance, shift closure, and intermittence phenomena are obtained and interpreted in this context. Similar conclusions apply for nonrenewal processes when the memory between successive events is induced by a stochastic waiting time distribution.
Testing large-angle deviation from Gaussianity in CMB maps
Bernui, A; Teixeira, A F F
2010-01-01
A detection of the level of non-Gaussianity in the CMB data is essential to discriminate among inflationary models and also to test alternative primordial scenarios. However, the extraction of primordial non-Gaussianity is a difficult endeavor since several effects of non-primordial nature can produce non-Gaussianity. On the other hand, different statistical tools can in principle provide information about distinct forms of non-Gaussianity. Thus, any single statistical estimator cannot be sensitive to all possible forms of non-Gaussianity. In this context, to shed some light in the potential sources of deviation from Gaussianity in CMB data it is important to use different statistical indicators. In a recent paper we proposed two new large-angle non-Gaussianity indicators which provide measures of the departure from Gaussianity on large angular scales. We used these indicators to carry out analyses of non-Gaussianity of the bands and of the foreground-reduced WMAP maps with and without the KQ75 mask. Here we ...
Characterizing pathological deviations from normality using constrained manifold-learning.
Duchateau, Nicolas; De Craene, Mathieu; Piella, Gemma; Frangi, Alejandro F
2011-01-01
We propose a technique to represent a pathological pattern as a deviation from normality along a manifold structure. Each subject is represented by a map of local motion abnormalities, obtained from a statistical atlas of motion built from a healthy population. The algorithm learns a manifold from a set of patients with varying degrees of the same pathology. The approach extends recent manifold-learning techniques by constraining the manifold to pass by a physiologically meaningful origin representing a normal motion pattern. Individuals are compared to the manifold population through a distance that combines a mapping to the manifold and the path along the manifold to reach its origin. The method is applied in the context of cardiac resynchronization therapy (CRT), focusing on a specific motion pattern of intra-ventricular dyssynchrony called septal flash (SF). We estimate the manifold from 50 CRT candidates with SF and test it on 38 CRT candidates and 21 healthy volunteers. Experiments highlight the need of nonlinear techniques to learn the studied data, and the relevance of the computed distance for comparing individuals to a specific pathological pattern.
A Maximum Likelihood Approach to Least Absolute Deviation Regression
Yinbo Li
2004-09-01
Full Text Available Least absolute deviation (LAD regression is an important tool used in numerous applications throughout science and engineering, mainly due to the intrinsic robust characteristics of LAD. In this paper, we show that the optimization needed to solve the LAD regression problem can be viewed as a sequence of maximum likelihood estimates (MLE of location. The derived algorithm reduces to an iterative procedure where a simple coordinate transformation is applied during each iteration to direct the optimization procedure along edge lines of the cost surface, followed by an MLE of location which is executed by a weighted median operation. Requiring weighted medians only, the new algorithm can be easily modularized for hardware implementation, as opposed to most of the other existing LAD methods which require complicated operations such as matrix entry manipulations. One exception is Wesolowsky's direct descent algorithm, which among the top algorithms is also based on weighted median operations. Simulation shows that the new algorithm is superior in speed to Wesolowsky's algorithm, which is simple in structure as well. The new algorithm provides a better tradeoff solution between convergence speed and implementation complexity.
Inertial Manifold and Large Deviations Approach to Reduced PDE Dynamics
Cardin, Franco; Favretti, Marco; Lovison, Alberto
2017-09-01
In this paper a certain type of reaction-diffusion equation—similar to the Allen-Cahn equation—is the starting point for setting up a genuine thermodynamic reduction i.e. involving a finite number of parameters or collective variables of the initial system. We firstly operate a finite Lyapunov-Schmidt reduction of the cited reaction-diffusion equation when reformulated as a variational problem. In this way we gain a finite-dimensional ODE description of the initial system which preserves the gradient structure of the original one and that is exact for the static case and only approximate for the dynamic case. Our main concern is how to deal with this approximate reduced description of the initial PDE. To start with, we note that our approximate reduced ODE is similar to the approximate inertial manifold introduced by Temam and coworkers for Navier-Stokes equations. As a second approach, we take into account the uncertainty (loss of information) introduced with the above mentioned approximate reduction by considering the stochastic version of the ODE. We study this reduced stochastic system using classical tools from large deviations, viscosity solutions and weak KAM Hamilton-Jacobi theory. In the last part we suggest a possible use of a result of our approach in the comprehensive treatment non equilibrium thermodynamics given by Macroscopic Fluctuation Theory.
Kunioka, Masao
2010-06-01
The biomass carbon ratios of biochemicals related to biomass have been reviewed. Commercial products from biomass were explained. The biomass carbon ratios of biochemical compounds were measured by accelerator mass spectrometry (AMS) based on the (14)C concentration of carbons in the compounds. This measuring method uses the mechanism that biomass carbons include a very low level of (14)C and petroleum carbons do not include (14)C similar to the carbon dating measuring method. It was confirmed that there were some biochemicals synthesized from petroleum-based carbons. This AMS method has a high accuracy with a small standard deviation and can be applied to plastic products.
Analysis on the Isotopic Ratio of Picogram Pu by TIMS%皮克量级钚同位素丰度比的TIMS分析
杨天丽; 龙开明; 刘雪梅; 刘钊; 汤磊
2005-01-01
The isotopic abundance ratios for Pu at 6.7 pg level were measured by thermal surface ionization mass spectrometry (TIMS). During the preparation of Pu samples carbon power was used as an emitting and stabilizing reagent, which increase the collection efficiency, the ion current intense and the ion emission stability for Pu. The measurment results indicate that the relative standard deviation of 2.7% for the isotopic abundance ratios of 240Pu to 239Pu is achieved when the 240Pu ion current is 8-20 cps.
Lantes, B. [Electricite de France (EDF-DPN/Groupe Environnement), 31 - Toulouse (France); Bienvenu, Ph. [CEA Cadarache, Dept. d' Etudes des Dechets, DED, 13 - Saint-Paul-lez-Durance (France)
2001-07-01
This paper presents the type of declaration of radioactivity in the wastes of PWR type reactors park. Particularly, it insists on the justification of use of spectra for the declaration of short live radionuclides. It tackles the important developments of methods and measures of radiochemical analysis made by the Cea in order to determine the ratios to declare the long life radioisotopes. (N.C.)
Back in the saddle: Large-deviation statistics of the cosmic log-density field
Uhlemann, Cora; Pichon, Christophe; Bernardeau, Francis; Reimberg, Paulo
2015-01-01
We present a first principle approach to obtain analytical predictions for spherically-averaged cosmic densities in the mildly non-linear regime that go well beyond what is usually achieved by standard perturbation theory. A large deviation principle allows us to compute the leading-order cumulants of average densities in concentric cells. In this symmetry, the spherical collapse model leads to cumulant generating functions that are robust for finite variances and free of critical points when logarithmic density transformations are implemented. They yield in turn accurate density probability distribution functions (PDFs) from a straightforward saddle-point approximation valid for all density values. Based on this easy-to-implement modification, explicit analytic formulas for the evaluation of the one- and two-cell PDF are provided. The theoretical predictions obtained for the PDFs are accurate to a few percent compared to the numerical integration, regardless of the density under consideration and in excellen...
Classical diffusion and quantum level velocities: systematic deviations from random matrix theory.
Lakshminarayan, A; Cerruti, N R; Tomsovic, S
1999-10-01
We study the response of the quasienergy levels in the context of quantized chaotic systems through the level velocity variance and relate them to classical diffusion coefficients using detailed semiclassical analysis. The systematic deviations from random matrix theory, assuming independence of eigenvectors from eigenvalues, are shown to be connected to classical higher-order time correlations of the chaotic system. We study the standard map as a specific example, and thus the well-known oscillatory behavior of the diffusion coefficient with respect to the parameter is reflected exactly in the oscillations of the variance of the level velocities. We study the case of mixed phase-space dynamics as well and note a transition in the scaling properties of the variance that occurs along with the classical transition to chaos.
Simple Strehl ratio based method for pupil phase mask's optimization in wavefront coding system
Wenzi Zhang; Yanping Chen; Tingyu Zhao; Zi Ye; Feihong Yu
2006-01-01
@@ By applying the wavefront coding technique to an optical system,the depth of focus can be greatly increased.Several complicated methods have already been taken to optimize for the best pupil phase mask in ideal condition.Here a simple Strehl ratio based method with only the standard deviation method used to evaluate the Strehl ratio stability over the depth of focus is applied to optimize for the best coefficients of pupil phase mask in practical optical systems.Results of imaging simulations for optical systems with and without pupil phase mask are presented,and the sharpness of image is calculated for comparison.The optimized pupil phase mask shows good results in extending the depth of focus.
SOME SMALL DEVIATION THEOREMS FOR ARBITRARY CONTINUOUS RANDOM SEQUENCE
Wang Zhongzhi
2007-01-01
Let (Xn)n∈N be a sequence of arbitrary continuous random variables, by the notion of relative entropy h(μ)μ(ω) as a measure of dissimilarity between probability measure μ and reference measure (μ), the explicit, general bounds for the partial sums of arbitrary continuous random variables under suitable conditions are developed. The argument uses the known and elementary lemma of convergence for likelihood ratio.
Ohata, Masaki; Nonose, Naoko; Dorta, Ladina; Günther, Detlef
2015-01-01
The analytical performance of 265 nm femtosecond laser ablation (fs-LA) and 213 nm nanosecond laser ablation (ns-LA) systems coupled with multi-collector inductively coupled plasma mass spectrometry (MC-ICPMS) for Pb isotope ratio measurements of solder were compared. Although the time-resolved signals of Pb measured by fs-LA-MC-ICPMS showed smoother signals compared to those obtained by ns-LA-MC-ICPMS, similar precisions on Pb isotope ratio measurements were obtained between them, even though their operating conditions were slightly different. The mass bias correction of the Pb isotope ratio measurement was carried out by a comparison method using a Pb standard solution prepared from NIST SRM 981 Pb metal isotopic standard, which was introduced into the ICP by a desolvation nebulizer (DSN) via a dual-sample introduction system, and it was successfully demonstrated for Pb isotope ratio measurements for either NIST 981 metal isotopic standard or solder by fs-LA-MC-ICPMS since the analytical results agreed well with the certified value as well as the determined value within their standard deviations obtained and the expanded uncertainty of the certified or determined value. The Pb isotope ratios of solder obtained by ns-LA-MC-ICPMS also showed agreement with respect to the determined value within their standard deviations and expanded uncertainty. From these results, it was evaluated that the mass bias correction applied in the present study was useful and both LA-MC-ICPMS could show similar analytical performance for the Pb isotope ratio microanalysis of metallic samples such as solder.
Obtaining reliable Likelihood Ratio tests from simulated likelihood functions
Andersen, Laura Mørch
It is standard practice by researchers and the default option in many statistical programs to base test statistics for mixed models on simulations using asymmetric draws (e.g. Halton draws). This paper shows that when the estimated likelihood functions depend on standard deviations of mixed...
Direct uranium isotope ratio analysis of single micrometer-sized glass particles.
Kappel, Stefanie; Boulyga, Sergei F; Prohaska, Thomas
2012-11-01
We present the application of nanosecond laser ablation (LA) coupled to a 'Nu Plasma HR' multi collector inductively coupled plasma mass spectrometer (MC-ICP-MS) for the direct analysis of U isotope ratios in single, 10-20 μm-sized, U-doped glass particles. Method development included studies with respect to (1) external correction of the measured U isotope ratios in glass particles, (2) the applied laser ablation carrier gas (i.e. Ar versus He) and (3) the accurate determination of lower abundant (236)U/(238)U isotope ratios (i.e. 10(-5)). In addition, a data processing procedure was developed for evaluation of transient signals, which is of potential use for routine application of the developed method. We demonstrate that the developed method is reliable and well suited for determining U isotope ratios of individual particles. Analyses of twenty-eight S1 glass particles, measured under optimized conditions, yielded average biases of less than 0.6% from the certified values for (234)U/(238)U and (235)U/(238)U ratios. Experimental results obtained for (236)U/(238)U isotope ratios deviated by less than -2.5% from the certified values. Expanded relative total combined standard uncertainties U(c) (k = 2) of 2.6%, 1.4% and 5.8% were calculated for (234)U/(238)U, (235)U/(238)U and (236)U/(238)U, respectively. Copyright © 2012 Elsevier Ltd. All rights reserved.
X-ray dual energy spectral parameter optimization for bone Calcium/Phosphorus mass ratio estimation
Sotiropoulou, P. I.; Fountos, G. P.; Martini, N. D.; Koukou, V. N.; Michail, C. M.; Valais, I. G.; Kandarakis, I. S.; Nikiforidis, G. C.
2015-09-01
Calcium (Ca) and Phosphorus (P) bone mass ratio has been identified as an important, yet underutilized, risk factor in osteoporosis diagnosis. The purpose of this simulation study is to investigate the use of effective or mean mass attenuation coefficient in Ca/P mass ratio estimation with the use of a dual-energy method. The investigation was based on the minimization of the accuracy of Ca/P ratio, with respect to the Coefficient of Variation of the ratio. Different set-ups were examined, based on the K-edge filtering technique and single X-ray exposure. The modified X-ray output was attenuated by various Ca/P mass ratios resulting in nine calibration points, while keeping constant the total bone thickness. The simulated data were obtained considering a photon counting energy discriminating detector. The standard deviation of the residuals was used to compare and evaluate the accuracy between the different dual energy set-ups. The optimum mass attenuation coefficient for the Ca/P mass ratio estimation was the effective coefficient in all the examined set-ups. The variation of the residuals between the different set-ups was not significant.
Outcomes of minimally invasive strabismus surgery for horizontal deviation.
Merino, P; Blanco Domínguez, I; Gómez de Liaño, P
2016-02-01
To study the outcomes of minimally invasive strabismus surgery (MISS) for treating horizontal deviation Case Series of the first 26 consecutive patients operated on using the MISS technique in our hospital from February 2010 to March 2014. A total of 40 eyes were included: 26 patients (mean age: 7.7 years old ± 4.9); 34.61%: male. A total of 43 muscles were operated on: 20 medial, and 23 lateral recti; 28 recessions (range: 3-7.5mm), 6 resections (6-7 mm), and 9 plications (6.5-7.5 mm) were performed. No significant difference was found (P>0.05) for visual acuity at postoperative day 1, and 6 months after surgery. A mild hyperaemia was observed in 29.27%, moderate in 48.78%, and severe in 21.95% at postoperative day 1 and in 63.41%, 31.70% and 4.87%, respectively, at 4 days after surgery. The complications observed were 4 intraoperative conjunctival haemorrhages, 1 scleral perforation, and 2 Tenon's prolapses. A conversion from MISS to a fornix approach was necessary in 1 patient because of bad visualization. The operating time range decreased from 30 to 15 minutes. The MISS technique has obtained good results in horizontal strabismus surgery. The conjunctival inflammation was mild in most of the cases at postoperative day 4. The visual acuity was stable during follow-up, and operating time decreased after a 4-year learning curve. Copyright © 2015 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.
Large-deviation statistics of vorticity stretching in isotropic turbulence.
Johnson, Perry L; Meneveau, Charles
2016-03-01
A key feature of three-dimensional fluid turbulence is the stretching and realignment of vorticity by the action of the strain rate. It is shown in this paper, using the cumulant-generating function, that the cumulative vorticity stretching along a Lagrangian path in isotropic turbulence obeys a large deviation principle. As a result, the relevant statistics can be described by the vorticity stretching Cramér function. This function is computed from a direct numerical simulation data set at a Taylor-scale Reynolds number of Re(λ)=433 and compared to those of the finite-time Lyapunov exponents (FTLE) for material deformation. As expected, the mean cumulative vorticity stretching is slightly less than that of the most-stretched material line (largest FTLE), due to the vorticity's preferential alignment with the second-largest eigenvalue of strain rate and the material line's preferential alignment with the largest eigenvalue. However, the vorticity stretching tends to be significantly larger than the second-largest FTLE, and the Cramér functions reveal that the statistics of vorticity stretching fluctuations are more similar to those of the largest FTLE. In an attempt to relate the vorticity stretching statistics to the vorticity magnitude probability density function in statistically stationary conditions, a model Kramers-Moyal equation is constructed using the statistics encoded in the Cramér function. The model predicts a stretched-exponential tail for the vorticity magnitude probability density function, with good agreement for the exponent but significant difference (35%) in the prefactor.
Symphysis-fundal height curve in the diagnosis of fetal growth deviations
Djacyr Magna Cabral Freire
2010-12-01
Full Text Available OBJECTIVE: To validate a new symphysis-fundal curve for screening fetal growth deviations and to compare its performance with the standard curve adopted by the Brazilian Ministry of Health. METHODS: Observational study including a total of 753 low-risk pregnant women with gestational age above 27 weeks between March to October 2006 in the city of João Pessoa, Northeastern Brazil. Symphisys-fundal was measured using a standard technique recommended by the Brazilian Ministry of Health. Estimated fetal weight assessed through ultrasound using the Brazilian fetal weight chart for gestational age was the gold standard. A subsample of 122 women with neonatal weight measurements was taken up to seven days after estimated fetal weight measurements and symphisys-fundal classification was compared with Lubchenco growth reference curve as gold standard. Sensitivity, specificity, positive and negative predictive values were calculated. The McNemar χ2 test was used for comparing sensitivity of both symphisys-fundal curves studied. RESULTS: The sensitivity of the new curve for detecting small for gestational age fetuses was 51.6% while that of the Brazilian Ministry of Health reference curve was significantly lower (12.5%. In the subsample using neonatal weight as gold standard, the sensitivity of the new reference curve was 85.7% while that of the Brazilian Ministry of Health was 42.9% for detecting small for gestational age. CONCLUSIONS: The diagnostic performance of the new curve for detecting small for gestational age fetuses was significantly higher than that of the Brazilian Ministry of Health reference curve.
[Study on the correlation between chronic sinusitis with nasal septum deviation].
Ji, Xiaoqing; Fu, Hongjuan; Song, Aiqin
2015-06-01
Study on the correlation between chronic sinusitis with nasal septum deviation. Randomly selected 722 patients with coronal sinuses CT, statistics the number of cases of nasal septum deviation, cases of nasal septum deviation with chronic sinusitis, the wide and narrow side cases of nasal septum deviation complicated with sinusitis. The number of sinusitis without deviation, and paired test. The incidence of sinusitis between deviation of nasal septum and non deviation were 54. 13% and 44. 66%, the difference between two groups was statistically significant (Psinusitis with nasal septum deviation of wide and narrow side were 31. 65% and 32. 12%, no significant difference between the two groups (P>0. 01). The incidence of sinusitis high deviation and non high deviation were 59. 54% and 46. 97%, the difference between the two groups was statistically significant (Psinusitis was 54, the narrow side was 66, there is no significant difference between the two groups (P>0. 05). The deviation of nasal septum is associated with the formation of chronic sinusitis, the high deviation is more prone to sinusitis, The incidence of sinusitis and nasal septum deviation on both sides was no different.
Pröfrock, Daniel; Irrgeher, Johanna; Prohaska, Thomas
2016-01-01
The performance and validation characteristics of different single collector inductively coupled plasma mass spectrometers based on different technical principles (ICP-SFMS, ICP-QMS in reaction and collision modes, and ICP-MS/MS) were evaluated in comparison to the performance of MC ICP-MS for fast and reliable S isotope ratio measurements. The validation included the determination of LOD, BEC, measurement repeatability, within-lab reproducibility and deviation from certified values as well as a study on instrumental isotopic fractionation (IIF) and the calculation of the combined standard measurement uncertainty. Different approaches of correction for IIF applying external intra-elemental IIF correction (aka standard-sample bracketing) using certified S reference materials and internal inter-elemental IIF (aka internal standardization) correction using Si isotope ratios in MC ICP-MS are explained and compared. The resulting combined standard uncertainties of examined ICP-QMS systems were not better than 0.3–0.5% (uc,rel), which is in general insufficient to differentiate natural S isotope variations. Although the performance of the single collector ICP-SFMS is better (single measurement uc,rel = 0.08%), the measurement reproducibility (>0.2%) is the major limit of this system and leaves room for improvement. MC ICP-MS operated in the edge mass resolution mode, applying bracketing for correction of IIF, provided isotope ratio values with the highest quality (relative combined measurement uncertainty: 0.02%; deviation from the certified value: <0.002%). PMID:27812369
Hanousek, Ondrej; Brunner, Marion; Pröfrock, Daniel; Irrgeher, Johanna; Prohaska, Thomas
2016-11-14
The performance and validation characteristics of different single collector inductively coupled plasma mass spectrometers based on different technical principles (ICP-SFMS, ICP-QMS in reaction and collision modes, and ICP-MS/MS) were evaluated in comparison to the performance of MC ICP-MS for fast and reliable S isotope ratio measurements. The validation included the determination of LOD, BEC, measurement repeatability, within-lab reproducibility and deviation from certified values as well as a study on instrumental isotopic fractionation (IIF) and the calculation of the combined standard measurement uncertainty. Different approaches of correction for IIF applying external intra-elemental IIF correction (aka standard-sample bracketing) using certified S reference materials and internal inter-elemental IIF (aka internal standardization) correction using Si isotope ratios in MC ICP-MS are explained and compared. The resulting combined standard uncertainties of examined ICP-QMS systems were not better than 0.3-0.5% (uc,rel), which is in general insufficient to differentiate natural S isotope variations. Although the performance of the single collector ICP-SFMS is better (single measurement uc,rel = 0.08%), the measurement reproducibility (>0.2%) is the major limit of this system and leaves room for improvement. MC ICP-MS operated in the edge mass resolution mode, applying bracketing for correction of IIF, provided isotope ratio values with the highest quality (relative combined measurement uncertainty: 0.02%; deviation from the certified value: <0.002%).
Problems using ratios of galaxy shape moments in requirements for weak lensing surveys
Israel, H.; Kitching, T. D.; Massey, R.; Cropper, M.
2017-01-01
Context. The shapes of galaxies are typically quantified by ratios of their quadrupole moments. Knowledge of these ratios (i.e. their measured standard deviation) is commonly used to assess the efficiency of weak gravitational lensing surveys. For faint galaxies, observational noise can make the denominator close to zero, so the ratios become ill-defined. Aims: Since the requirements cannot be formally tested for faint galaxies, we explore two complementary mitigation strategies. In many weak lensing contexts, the most problematic sources can be removed by a cut in measured size. This first technique is applied frequently. As our second strategy, we propose requirements directly on the quadrupole moments rather than their ratio. Methods: As an example of the first strategy, we have investigated how a size cut affects the required precision of the charge transfer inefficiency model for two shape measurement settings. For the second strategy, we analysed the joint likelihood distribution of the image quadrupole moments measured from simulated galaxies, and propagate their (correlated) uncertainties into ellipticities. Results: Using a size cut, we find slightly wider tolerance margins for the charge transfer inefficiency parameters compared to the full size distribution. However, subtle biases in the data analysis chain may be introduced. These can be avoided using the second strategy. To optimally exploit a Stage-IV dark energy survey, we find that the mean and standard deviation of a population of galaxies' quadrupole moments must to be known to better than 1.4 × 10-3 arcsec2, or the Stokes parameters to 1.9 × 10-3 arcsec2. Conclusions: Cuts in measured size remove sources that otherwise make ellipticity statistics of weak lensing galaxy samples diverge. However, size cuts bias the source population non-trivially. Assessing weak lensing data quality directly on the quadrupole moments instead mitigates the need for size cuts. Such testable requirements can form
Li, Yongqiang; Hsi, Wen C.
2017-04-01
To analyze measurement deviations of patient-specific quality assurance (QA) using intensity-modulated spot-scanning particle beams, a commercial radiation dosimeter using 24 pinpoint ionization chambers was utilized. Before the clinical trial, validations of the radiation dosimeter and treatment planning system were conducted. During the clinical trial 165 measurements were performed on 36 enrolled patients. Two or three fields of particle beam were used for each patient. Measurements were typically performed with the dosimeter placed at special regions of dose distribution along depth and lateral profiles. In order to investigate the dosimeter accuracy, repeated measurements with uniform dose irradiations were also carried out. A two-step approach was proposed to analyze 24 sampling points over a 3D treatment volume. The mean value and the standard deviation of each measurement did not exceed 5% for all measurements performed on patients with various diseases. According to the defined intervention thresholds of mean deviation and the distance-to-agreement concept with a Gamma index analysis using criteria of 3.0% and 2 mm, a decision could be made regarding whether the dose distribution was acceptable for the patient. Based measurement results, deviation analysis was carried out. In this study, the dosimeter was used for dose verification and provided a safety guard to assure precise dose delivery of highly modulated particle therapy. Patient-specific QA will be investigated in future clinical operations.
Determination of the onset time in polarization power ratio Z/H for precursor of Sumatra earthquake
Ahadi, S., E-mail: su4idi@yahoo.com [Faculty of Earth Sciences and Technology, Bandung Institute of Technology, Jl. Ganesha No.10, Bandung 40132 (Indonesia); Puspito, N. T.; Ibrahim, G. [Faculty of Mining and Petroleum Engineering, Bandung Institute of Technology, Jl. Ganesha No.10 Bandung 40132 (Indonesia); Saroso, S. [National Institute of Aeronautic and Space (LAPAN), Jl. Djunjunan No. 133, Bandung 40173 (Indonesia)
2014-09-25
Determination of onset time precursors of strong earthquakes (Mw > 5) and distance (d < 500 km) using geomagnetic data from Geomagnetic station KTB, Sumatra and two station references DAV, Philippine and DAW, Australia. separate techniques are required in its determination. Not the same as that recorded in the kinetic wave seismograms can be determined by direct time domain. Difficulties associated with electromagnetic waves seismogenic activities require analysis of the transformed signal in the frequency domain. Determination of the frequency spectrum will determine the frequency of emissions emitted from the earthquake source. The aim is to analyze the power amplitude of the ULF emissions in the horizontal component (H) and vertical component (Z). Polarization power ratio Z/H is used for determining the sign of earthquake precursors controlled by the standard deviation. The pattern recognition polarization ratio should be obtained which can differentiate emissions from seismogenic effects of geomagnetic activity. ULF emission patterns generated that seismogenic effect has duration > 5 days and the dominance of emission intensity recorded at the Z component and for the dominance of the emission intensity of geomagnetic activity recorded in the component H. The result shows that the onset time is determined when the polarization power ratio Z/H standard deviation over the limit (p ± 2 σ) which has a duration of > 5 days.
Moderate deviations for the quenched mean of the super-Brownian motion with random immigration
2008-01-01
Moderate deviations for the quenched mean of the super-Brownian motion with random immigration are proved for 3≤d≤6, which fills in the gap between central limit theorem(CLT)and large deviation principle(LDP).
MODERATE DEVIATIONS FROM HYDRODYNAMIC LIMIT OF A GINZBURG-LANDAU MODEL
无
2006-01-01
The authors consider the moderate deviations of hydrodynamic limit for Ginzburg-Landau models. The moderate deviation principle of hydrodynamic limit for a specific Ginzburg-Landau model is obtained and an explicit formula of the rate function is derived.
Effects of carbonate leaching on foraminifer stable isotopes ratios
Obrochta, S.; Yokoyama, Y.; Sakai, S.; Ishimura, T.
2011-12-01
Stable carbon and oxygen isotope ratios were measured on 125 individual epifaunal and infaunal benthic foraminifers from two discrete Holocene intervals in a shallow-water sediment core (~ 450 m) from the Timor Sea. Methane seeps are common in the area, resulting in significant precipitation of secondary calcite that is confirmed by SEM photomicrographs and has likely resulted in inconsistent downcore results. To assess the degree of removal of contaminants, individual Uvigerina peregrina were subjected to varying degrees of pretreatment prior to analysis. All foraminifers received standard cleaning with ethanol and brief sonication. A subset were further cleaned and sonicated in a dilute HCl solution (~ 0.003 M). Foraminifer tests were photographed using both reflected light and scanning electron microscopes during the course of treatment to monitor the changing degree of contaminant removal as increasingly aggressive cleaning methods were employed. Visible contamination remained on individuals not subjected to HCl treatment. The leached individuals exhibit a lower overall relative standard deviation and consistent results within morphotype groups. Based on these results, a 2% value is expected to be typical of the Holocene, though further downcore analyses are pending restoration of equipment adversely effected by the Eastern Japan 3/11 earthquake.
Gorman, Jamie C; Amazeen, Polemnia G; Crites, Michael J; Gipson, Christina L
2017-02-10
In activities such as dancing and sports, people synchronize behaviors in many different ways. Synchronization between people has traditionally been characterized as either perfect mirroring (1:1 in-phase synchronization, spontaneous synchrony, and mimicry) or reflectional mirroring (1:1 antiphase synchronization), but most activities require partners to synchronize more complicated patterns. We asked visually coupled dyads to coordinate finger movements to perform multifrequency ratios (1:1, 2:1, 3:1, 4:1, and 5:1). Because these patterns are coordinated across and not just within individual physiological and motor systems, we based our predictions on frequency-locking dynamics, which is a general coordination principle that is not limited to physiological explanations. Twenty dyads performed five multifrequency ratios under three levels of visual coupling, with half using a subcritical visual information update rate. The dynamical principle was supported, such that multifrequency performance tends to abide by the strictures of frequency locking. However, these constraints are relaxed if the visual information rate is beyond the critical information update rate. An analysis of turning points in the oscillatory finger movements suggested that dyads did not rely on this visual information to stabilize coordination. How the laboratory findings align with naturalistic observations of multifrequency performance in actual sports teams (Double Dutch) is discussed. Frequency-locking accounts not only for the human propensity for perfect mirroring but also for variations in performance when dyads deviate from mirroring.
Strong Deviation Theorems of the Binomial Distribution%关于二项分布的强偏差定理
王学武; 张宇超
2011-01-01
利用分析方法建立了用不等式表示的用渐近平均对数似然比刻划的服从二项分布的随机变量序列的强偏差定理,作为推论得到了服从二项分布的相依随机变量序列的强大数定律.%In this paper, the notion of the logarithmic likelihood ratio, as a measure of the deviation between a sequence of arbitrary random variables and a sequence of independent random variables with the binomial distribution, is introduced. Using the concept, we obtain the strong deviation theorems represented by inequalities. Meanwhile, we get the strong laws of the large numbers for the sequence of the dependent random variables obeyed the the binomial distributions.
无
2010-01-01
This paper studies the moderate deviations of real-valued extended negatively dependent(END) random variables with consistently varying tails.The moderate deviations of partial sums are first given.The results are then used to establish the necessary and sufficient conditions for the moderate deviations of random sums under certain circumstances.
Parameterization for Neutrino Mixing Matrix with Deviated Unitarity
LU Lei; WANG Wen-Yu; XIONG Zhao-Hua
2009-01-01
Neutrino oscillation experiments provide the first evidence on non-zero neutrino masses and indicate new physics beyond the standard model.With Majorana neutrinos introduced to acquire tiny neutrino maases,it leads to the existence of more than three neutrino species,implying that the ordinary neutrino mixing matrix is only a part of the whole extended unitary mixing matrix and thus no longer unitary.We give a parameterization for a non-unitary neutrino mixing matrix under seesaw framework and further present a method to test the unitarity of the ordinary neutrino mixing matrix.
Abraha, Iosief; Cozzolino, Francesco; Orso, Massimiliano; Marchesi, Mauro; Germani, Antonella; Lombardo, Guido; Eusebi, Paolo; De Florio, Rita; Luchetta, Maria Laura; Iorio, Alfonso; Montedori, Alessandro
2017-04-01
To describe the characteristics, and estimate the incidence, of trials included in systematic reviews deviating from the intention-to-treat (ITT) principle. A 5% random sample of reviews were selected (Medline 2006-2010). Trials from reviews were classified based on the ITT: (1) ITT trials (trials reporting standard ITT analyses); (2) modified ITT (mITT) trials (modified ITT; trials deviating from standard ITT); or (3) no ITT trials. Of 222 reviews, 81 (36%) included at least one mITT trial. Reviews with mITT trials were more likely to contain trials that used placebo, that investigated drugs, and that reported favorable results. The incidence of reviews with mITT trial ranged from 29% (17/58) to 48% (23/48). Of the 2,349 trials, 597 (25.4%) were classified as ITT trials, 323 (13.8%) as mITT trials, and 1,429 (60.8%) as no ITT trials. The mITT trials were more likely to have reported exclusions compared to studies classified as ITT trials and to have received funding. The reporting of the type of ITT may differ according to the clinical area and the type of intervention. Deviation from ITT in randomized controlled trials is a widespread phenomenon that significantly affects systematic reviews. Copyright © 2017 Elsevier Inc. All rights reserved.
Deviation from power law of the global seismic moment distribution
Serra, Isabel; Corral, Álvaro
2017-01-01
The distribution of seismic moment is of capital interest to evaluate earthquake hazard, in particular regarding the most extreme events. We make use of likelihood-ratio tests to compare the simple Gutenberg-Richter power-law (PL) distribution with two statistical models that incorporate an exponential tail, the so-called tapered Gutenberg-Richter (Tap) and the truncated gamma, when fitted to the global CMT earthquake catalog. Although the Tap distribution does not introduce any significant improvement of fit respect the PL, the truncated gamma does. Simulated samples of this distribution, with parameters β = 0.68 and mc = 9.15 and reshuffled in order to mimic the time occurrence of the order statistics of the empirical data, are able to explain the temporal heterogeneity of global seismicity both before and after the great Sumatra-Andaman earthquake of 2004. PMID:28053311
CCSSM Challenge: Graphing Ratio and Proportion
Kastberg, Signe E.; D'Ambrosio, Beatriz S.; Lynch-Davis, Kathleen; Mintos, Alexia; Krawczyk, Kathryn
2013-01-01
A renewed emphasis was placed on ratio and proportional reasoning in the middle grades in the Common Core State Standards for Mathematics (CCSSM). The expectation for students includes the ability to not only compute and then compare and interpret the results of computations in context but also interpret ratios and proportions as they are…
Two-Phase Flow in Porous Media: Predicting Its Dependence on Capillary Number and Viscosity Ratio
Ferer, M. [National Energy Technology Lab. (NETL), Morgantown, WV (United States); West Virginia Univ., Morgantown, WV (United States); Anna, Shelley L. [National Energy Technology Lab. (NETL), Morgantown, WV (United States); Carnegie Mellon Univ., Pittsburgh, PA (United States); Tortora, Paul [National Energy Technology Lab. (NETL), Morgantown, WV (United States); Carnegie Mellon Univ., Pittsburgh, PA (United States); Kadambi, J. R. [Case Western Reserve Univ., Cleveland, OH (United States); Oliver, M. [Case Western Reserve Univ., Cleveland, OH (United States); Bromhal, Grant S. [National Energy Technology Lab. (NETL), Morgantown, WV (United States); Smith, Duane H. [National Energy Technology Lab. (NETL), Morgantown, WV (United States); West Virginia Univ., Morgantown, WV (United States)
2011-01-01
Motivated by the need to determine the dependencies of two-phase flow in a wide range of applications from carbon dioxide sequestration to enhanced oil recovery, we have developed a standard two-dimensional, pore-level model of immiscible drainage, incorporating viscous and capillary effects. This model has been validated through comparison with several experiments. For a range of stable viscosity ratios (M=μ_{injected,nwf}/μ_{defending,wf} ≥ 1), we had increased the capillary number, N_{c} and studied the way in which the flows deviate from fractal capillary fingering at a characteristic time and become compact for realistic capillary numbers. This crossover has enabled predictions for the dependence of the flow behavior upon capillary number and viscosity ratio. Our results for the crossover agreed with earlier theoretical predictions, including the universality of the leading power-law indicating its independence of details of the porous medium structure. In this article, we have observed a similar crossover from initial fractal viscous fingering (FVF) to compact flow, for large capillary numbers and unstable viscosity ratios M < 1. In this case, we increased the viscosity ratio from infinitesimal values, and studied the way in which the flows deviate from FVF at a characteristic time and become compact for non-zero viscosity ratios. This crossover has been studied using both our pore-level model and micro-fluidic flow-cell experiments. The same characteristic time, τ = 1/M^{0.7}, satisfactorily describes both the pore-level results.
Rutkowska-Ziarko Anna
2015-06-01
Full Text Available A study was conducted of 15 food companies listed on the Warsaw Stock Exchange. The profitability of companies was measured by: return on assets (ROA, return on equity (ROE and return on sales (ROS. Investment risk was measured by standard deviation and semi-deviation. The main objective of the study was to examine whether the average level and variability of selected indicators of profitability are reflected in the average level and the variability of returns on the capital market. An additional aim was to examine whether the size of the company affects the profitability and risk of investment in stocks as well as the average value and the volatility of profitability ratios. A positive correlation between the average value of the profitability ratios (ROA and ROS and the average rates of return on the capital market was identified. Similarly, companies with higher volatility and semi-volatility of profitability ratios were simultaneously characterized by larger fluctuations in rates of return on the stock market. Studies have shown that the size of the company is negatively correlated with the risk of stock market investments and the volatility of profitability ratios.
Large deviations for Markov chains in the positive quadrant
Borovkov, A. A.; Mogul'skii, A. A.
2001-10-01
The paper deals with so-called N-partially space-homogeneous time-homogeneous Markov chains X(y,n), n=0,1,2,\\dots, X(y,0)=y, in the positive quadrant \\mathbb R^{2+}=\\{x=(x_2,x_2):x_1\\geqslant0,\\ x_2\\geqslant0\\}. These Markov chains are characterized by the following property of the transition probabilities P(y,A)=\\mathsf P(X(y,1)\\in A): for some N\\geqslant 0 the measure P(y,dx) depends only on x_2, y_2, and x_1-y_1 in the domain x_1>N, y_1>N, and only on x_1, y_1, and x_2-y_2 in the domain x_2>N, y_2>N. For such chains the asymptotic behaviour of \\displaystyle \\ln\\mathsf P\\Bigl(\\frac 1sX(y,n)\\in B\\Bigr), \\qquad \\ln\\mathsf P\\bigl(X(y,n)\\in x+B\\bigr) is found for a fixed set B as s\\to\\infty, \\vert x\\vert\\to\\infty, and n\\to\\infty. Some other conditions on the growth of parameters are also considered, for example, \\vert x-y\\vert\\to\\infty, \\vert y\\vert\\to\\infty. A study is made of the structure of the most probable trajectories, which give the main contribution to this asymptotics, and a number of other results pertaining to the topic are established. Similar results are obtained for the narrower class of 0-partially homogeneous ergodic chains under less restrictive moment conditions on the transition probabilities P(y,dx). Moreover, exact asymptotic expressions for the probabilities \\mathsf P(X(0,n)\\in x+B) are found for 0-partially homogeneous ergodic chains under some additional conditions. The interest in partially homogeneous Markov chains in positive octants is due to the mathematical aspects (new and interesting problems arise in the framework of general large deviation theory) as well as applied issues, for such chains prove to be quite accurate mathematical models for numerous basic types of queueing and communication networks such as the widely known Jackson networks, polling systems, or communication networks associated with the ALOHA algorithm. There is a vast literature dealing with the analysis of these objects. The
F. M. R. Mesquita
2012-09-01
Full Text Available Viscosities of four binaries mixtures [soybean biodiesel + diesel oil (or n-hexadecane and coconut biodiesel + diesel oil (or n-hexadecane] have been determined at T = (293.15, 313.15, 333.15, 353.15, 373.15 K and atmospheric pressure over the entire composition range. Experimental data were fitted to the Andrade equation and the adjustable parameters and the standard deviations between experimental and calculated values were estimated. From the experimental data, the viscosity deviations, , were calculated by using the Redlich - Kister polynomial equation. The comparison between experimental data determined in this work and four predictive methods used for the estimation of viscosities of biodiesel fuels (based on their fatty acid composition is discussed.
Marli - -
2012-05-01
Full Text Available ABSTRAK Penilaian harga saham berdasarkan analisa fundamental diklasifikasikan pada pendekatan dividend discount model dan P/E ratio. Permasalahan yang penting dalam penelitian ini menyangkut tentang aplikasi penilaian harga saham berdasarkan pendekatan PER dengan menggunakan variabel bebas yang dianggap relevan mempengaruhi harga saham. Selain itu, juga dapat digunakan untuk menjelaskan kondisi harga saham, variabel mana yang dominan dan bagaimana perubahan harga sahamnya dengan acuan pada pendekatan P/E ratio. Variabel yang dipertimbangkan oleh investor dalam melakukan investasi di pasar modal diantaranya dividend payout ratio, standard deviation of EPS, return on equity dan debt to equity ratio sedangkan earning growth tetap dipertimbangkan tetapi dengan tingkat signifikansi yang lebih rendah. Return on equity merupakan variabel penelitian yang paling dominan mempengaruhi harga saham. Harga saham di Bursa efek Jakarta belum menunjukkan harga yang wajar dan berdasarkan analisa teknikal dengan menggunakan indikator moving average dan trend, kecenderungan perubahan harga sahamnya tidak selalu menuju nilai intrinsiknya. Kata kunci: P/E ratio, return on equity, debt to equity ratio ABSTRACT The assessment of stock price based on fundamental analyse is grouped on model discount dividend approach and P/E ratio. The important problems in this research include assessment stock price application based on PER approach using independent variable which have relevant influence at stock price. It also used to explain stock price condition, dominant variable, and how is the changing of stock price with based on P/E ratio approach. Variable considered by investor on conducting investment in stock exchange market are: dividend payout ratio, standard deviation of EPS, return on equity, and debt to equity ratio while earning growth also considered but at lower significance level. Return on equity is dominant influence research variable on stock price. Stock
Measurement of the atmospheric muon charge ratio at TeV energies with MINOS
Adamson, P.; Andreopoulos, C.; Arms, K.E.; Armstrong, R.; Auty, D.J.; Avvakumov, S.; Ayres, D.S.; Baller, B.; Barish, B.; Barnes, P.D., Jr.; Barr, G.; /Fermilab /University Coll. London /Rutherford /Minnesota U. /Indiana U. /Sussex U. /Stanford U., Phys. Dept. /Argonne /Caltech /LLNL, Livermore /Oxford U.
2007-05-01
The 5.4 kton MINOS far detector has been taking charge-separated cosmic ray muon data since the beginning of August, 2003 at a depth of 2070 m.w.e. in the Soudan Underground Laboratory, Minnesota, USA. The data with both forward and reversed magnetic field running configurations were combined to minimize systematic errors in the determination of the underground muon charge ratio. When averaged, two independent analyses find the charge ratio underground to be N{sub {mu}}+/N{sub {mu}}-=1.374{+-}0.004(stat)-0.010{sup +0.012}(sys). Using the map of the Soudan rock overburden, the muon momenta as measured underground were projected to the corresponding values at the surface in the energy range 1-7 TeV. Within this range of energies at the surface, the MINOS data are consistent with the charge ratio being energy independent at the 2 standard deviation level. When the MINOS results are compared with measurements at lower energies, a clear rise in the charge ratio in the energy range 0.3-1.0 TeV is apparent. A qualitative model shows that the rise is consistent with an increasing contribution of kaon decays to the muon charge ratio.
Large-deviation joint statistics of the finite-time Lyapunov spectrum in isotropic turbulence
Johnson, Perry L., E-mail: pjohns86@jhu.edu; Meneveau, Charles [Department of Mechanical Engineering and Center for Environmental and Applied Fluid Mechanics, The Johns Hopkins University, 3400 N. Charles Street, Baltimore, Maryland 21218 (United States)
2015-08-15
One of the hallmarks of turbulent flows is the chaotic behavior of fluid particle paths with exponentially growing separation among them while their distance does not exceed the viscous range. The maximal (positive) Lyapunov exponent represents the average strength of the exponential growth rate, while fluctuations in the rate of growth are characterized by the finite-time Lyapunov exponents (FTLEs). In the last decade or so, the notion of Lagrangian coherent structures (which are often computed using FTLEs) has gained attention as a tool for visualizing coherent trajectory patterns in a flow and distinguishing regions of the flow with different mixing properties. A quantitative statistical characterization of FTLEs can be accomplished using the statistical theory of large deviations, based on the so-called Cramér function. To obtain the Cramér function from data, we use both the method based on measuring moments and measuring histograms and introduce a finite-size correction to the histogram-based method. We generalize the existing univariate formalism to the joint distributions of the two FTLEs needed to fully specify the Lyapunov spectrum in 3D flows. The joint Cramér function of turbulence is measured from two direct numerical simulation datasets of isotropic turbulence. Results are compared with joint statistics of FTLEs computed using only the symmetric part of the velocity gradient tensor, as well as with joint statistics of instantaneous strain-rate eigenvalues. When using only the strain contribution of the velocity gradient, the maximal FTLE nearly doubles in magnitude, highlighting the role of rotation in de-correlating the fluid deformations along particle paths. We also extend the large-deviation theory to study the statistics of the ratio of FTLEs. The most likely ratio of the FTLEs λ{sub 1} : λ{sub 2} : λ{sub 3} is shown to be about 4:1:−5, compared to about 8:3:−11 when using only the strain-rate tensor for calculating fluid volume
RELIGIOUS ANOMIE AS THE DEVIATION CATALYST IN THE MODERN SOCIETY
Alexander Vladislavovich Pletnev
2015-11-01
Full Text Available In the article features of influence of religion on the individual in the modern society are considered. In the XXI century the religion shows weak ability to execute functions of social control. At the same time the religion remains the major psychological factor which in many respects defines the maintenance of the vital world of individuals. Strengthening of influence of religion as psychological factor allows to study social consequences of this influence. If the classical sociological theory considers religion as a factor certainly constraining an anomy, in modern conditions the religion has rather opposite effect. The Christian religion shows the highest, unrealizable requirements to the individual.As a result of it the individuals strongly subject to influence of Christian values feel ina-bility to correspond to Christian model of ideal human behavior. The variety of religions in the modern society of the western type and conducting interreligious dialogue is other reason of development of religious anomy. The mutual erosion of the valuable and standard bases of each religion turns out to be consequence of this dialogue. In addition, modern society is characterized by essential distinction in understanding individuals of norms and principles of that religion which supporters they are.As for change of functioning of religion as social institute, in this aspect the increasing reorientation of religious institutes of the western society to the market purposes and values is observed. The specified processes in general will lead to increase of deviant behavior due to development of religious anomy.
CUSUM control charts based on likelihood ratio for preliminary analysis
Yi DAI; Zhao-jun WANG; Chang-liang ZOU
2007-01-01
To detect and estimate a shift in either the mean and the deviation or both for the preliminary analysis, the statistical process control (SPC) tool, the control chart based on the likelihood ratio test (LRT), is the most popular method.Sullivan and woodall pointed out the test statistic lrt (n1, n2) is approximately distributed as x2 (2) as the sample size n, n1 and n2 are very large, and the value of n1 = 2, 3,..., n- 2 and that of n2 = n- n1.So it is inevitable that n1 or n2 is not large. In this paper the limit distribution of lrt(n1, n2) for fixed n1 or n2 is figured out, and the exactly analytic formulae for evaluating the expectation and the variance of the limit distribution are also obtained.In addition, the properties of the standardized likelihood ratio statistic slr(n1,n) are discussed in this paper. Although slr(n1, n) contains the most important information, slr(i, n)(i ≠ n1) also contains lots of information. The cumulative sum (CUSUM) control chart can obtain more information in this condition. So we propose two CUSUM control charts based on the likelihood ratio statistics for the preliminary analysis on the individual observations. One focuses on detecting the shifts in location in the historical data and the other is more general in detecting a shift in either the location and the scale or both.Moreover, the simulated results show that the proposed two control charts are, respectively, superior to their competitors not only in the detection of the sustained shifts but also in the detection of some other out-of-control situations considered in this paper.
CUSUM control charts based on likelihood ratio for preliminary analysis
2007-01-01
To detect and estimate a shift in either the mean and the deviation or both for the preliminary analysis, the statistical process control (SPC) tool, the control chart based on the likelihood ratio test (LRT), is the most popular method. Sullivan and woodall pointed out the test statistic lrt(n1, n2) is approximately distributed as x2(2) as the sample size n,n1 and n2 are very large, and the value of n1 = 2,3,..., n - 2 and that of n2 = n - n1. So it is inevitable that n1 or n2 is not large. In this paper the limit distribution of lrt(n1, n2) for fixed n1 or n2 is figured out, and the exactly analytic formulae for evaluating the expectation and the variance of the limit distribution are also obtained. In addition, the properties of the standardized likelihood ratio statistic slr(n1, n) are discussed in this paper. Although slr(n1, n) contains the most important information, slr(i, n)(i≠n1) also contains lots of information. The cumulative sum (CUSUM) control chart can obtain more information in this condition. So we propose two CUSUM control charts based on the likelihood ratio statistics for the preliminary analysis on the individual observations. One focuses on detecting the shifts in location in the historical data and the other is more general in detecting a shift in either the location and the scale or both. Moreover, the simulated results show that the proposed two control charts are, respectively, superior to their competitors not only in the detection of the sustained shifts but also in the detection of some other out-of-control situations considered in this paper.
Stable isotope ratio analysis for verifying the authenticity of balsamic and wine vinegar.
Perini, M; Paolini, M; Simoni, M; Bontempo, L; Vrhovsek, U; Sacco, M; Thomas, F; Jamin, E; Hermann, A; Camin, F
2014-08-13
In this paper, we investigate whether the analysis of stable isotope ratios D/H and ¹³C/¹²C in ethanol and acetic acid and of ¹⁸O/¹⁶O in water can be applied to the ingredients of "aceto balsamico di Modena IGP" (ABM) to evaluate their authenticity. We found that impurities in the extraction solution do not affect the ¹³C/¹²C of acetic acid and the D/H values of acetic acid are not affected under a composite NMR experiment. The standard deviation of repeatability and standard deviation of reproducibility are comparable in wine vinegar and ABM and generally lower than those quoted in the official methods. This means that the validation parameters quoted in the official methods can also be applied to the ingredients of ABM. In addition, we found no changes in the isotopic values from wine to vinegar and to ABM, and from the original must to the ABM must, providing experimental evidence that reference data from wine databanks can also be used to evaluate the authenticity of vinegar and ABM.
Tănase Alin-Eliodor
2014-08-01
Full Text Available This article focuses on computing techniques starting from trial balance data regarding financial key ratios. There are presented activity, liquidity, solvency and profitability financial key ratios. It is presented a computing methodology in three steps based on a trial balance.
Collins, Mimi
1997-01-01
Explores how human resource professionals, with above average offer/acceptance ratios, streamline their recruitment efforts. Profiles company strategies with internships, internal promotion, cooperative education programs, and how to get candidates to accept offers. Also discusses how to use the offer/acceptance ratio as a measure of program…
Akkerman, J. W.
1982-01-01
New mechanism alters compression ratio of internal-combustion engine according to load so that engine operates at top fuel efficiency. Ordinary gasoline, diesel and gas engines with their fixed compression ratios are inefficient at partial load and at low-speed full load. Mechanism ensures engines operate as efficiently under these conditions as they do at highload and high speed.
Wyer, J C; Salzinger, F H
1983-01-01
Many common management techniques have little use in managing a medical group practice. Ratio analysis, however, can easily be adapted to the group practice setting. Acting as broad-gauge indicators, financial ratios provide an early warning of potential problems and can be very useful in planning for future operations. The author has gathered a collection of financial ratios which were developed by participants at an education seminar presented for the Virginia Medical Group Management Association. Classified according to the human element, system component, and financial factor, the ratios provide a good sampling of measurements relevant to medical group practices and can serve as an example for custom-tailoring a ratio analysis system for your medical group.
A study on the deviation aspects of the poem âThe Eightieth Stageâ
Soghra Salmaninejad Mehrabadi
2016-01-01
of synergistic base has helped to the poet's innovation. New expressions are also used in other parts of abnormality in âThe Eightieth Stag eâ . Stylistic deviation Sometimes, Akhavan uses local and slang words, and words with different songs and music produces deviation as well. This Application is one kind of abnormality. Words such as âhan, hey, by the truth, pity, hoome, kope, meydanak and ...â are of this type of abnormality . Â Ancient deviation One way to break out of the habit of poetry , is attention to ancient words and actions . Archaism is one of the factors affecting the deviation. Archaism deviation helps to make the old sp. According to Leach, the ancient is the survival of the old language in the now. Syntactic factors, type of music and words, are effective in escape from the standard language. âSowrat (sharpness, hamgenan (counterparts, parine (last year, pour ( son, pahlaw (championââare Words that show Akhavanâs attention to archaism. The ancient pronunciation is another part of his work. Furthermore, use of mythology and allusion have created deviation of this type. Cases such as anagram adjectival compounds, the use of two prepositions for a word, the use of the adjective and noun in the plural form, are signs of archaism in grammar and syntax. He is interested in grammatical elements of Khorasani Style. Most elements of this style used in âThe Eightieth Stageâ poetry. S emantic deviation Semantic deviation is caused by the imagery . The poet uses frequently literary figures. By this way, he produces new meaning and therefore highlights his poem. Simile, metaphor, personification and irony are the most important examples of this deviation. Apparently the maximum deviation from the norm in this poem is of periodic deviation (ancient or archaism. The second row belongs to the semantic deviation in which metaphor is the most meaningful. The effect of metaphor in this poem is quite well. In
The Standard Model confronts CP violation in $D^0 \\to \\pi^+\\pi^-$ and $D^0 \\to K^+K^-$
Franco, Enrico; Silvestrini, Luca
2012-01-01
The recently measured direct CP asymmetries in the processes $D^0\\to \\pi^+\\pi^-$ and $D^0\\to K^+K^-$ show a significant deviation from the naive Standard Model expectation. Using a general parameterization of the decay amplitudes, we show that the measured branching ratios imply large SU(3) breaking and large violations of the naive $1/N_c$ counting. Furthermore, rescattering constrains the I=0 amplitudes in the $\\pi\\pi$ and $KK$ channels. Combining all this information, we show that, with present errors, the observed asymmetries are marginally compatible with the Standard Model. Improving the experimental accuracy could lead to an indirect signal of new physics.
Deviation of permeable coarse-grained boundary resistance from Nikuradse's observations
Cheng, Nian-Sheng; Liu, Xingnian; Chen, Xingwei; Qiao, Changkai
2016-02-01
Nikuradse's (1933) rough pipe study is enormously influential in the understanding of flow resistance over a sediment bed. However, the rough boundary employed in Nikuradse's study differs from permeable sediment beds in rivers. This implies that the results derived from the rough pipe experiments may not be applicable for flows over a permeable coarse-grained bed. The present study aimed to explore to what extent the flow resistance of a permeable coarse-grained boundary deviates from the Nikuradse's observations. Experiments were conducted with rough pipes, which were prepared by overlaying the inner wall with one to four layers of spherical beads. The single layer roughness resembles the experimental setup reported in Nikuradse's study, while the multilayer of grains allows significant flow to pass through the porous roughness layer. In addition, the ratio of grain diameter, k, to pipe diameter, d, was chosen to be one to two orders greater than the range (0.001 measurements also suggest the existence of a laminar flow regime, in which the friction factor is inversely proportional to the Reynolds number. The observed variations in the flow resistance are attributed to both wall permeability and large-scale roughness.
P. I. Azubuike
2012-01-01
Full Text Available Problem statement: The Shewhart and S control charts, in the literature, were combined to evaluate the stability of a process. These charts were based on the fundamental assumption of normality of the quality characteristics under investigation. Approach: In practice, the normality assumption was often violated by real life data, therefore, use of the Shewhart and S control charts on real life data might leads to misplacement of control limits. There were many alternatives in the literature to handle non-normality of quality characteristics. The Median Absolute Deviation (MAD claimed in the literature to be the best estimate when the data under consideration is non-normal. Thus in this study, we derived the control limits for the-control chart using the median absolute deviation for monitoring process stability when the quality characteristic under investigation was non-normal. Results: The derived control limits were compared with the control limits when the sample standard deviation was used as a measure of controlling the process variability using manufacturing process (real life data. Furthermore, a simulation study was carried out to evaluate the performance of the proposed MAD based control charts on both normal and non-normal process. Conclusion: The obtained results show that the derived control limit is an improvement on the control limit of the Shewhart and that the MAD control charts performed better for non-normal process than for normal process.
Sex ratio strategies and the evolution of cue use
Moore, J.; Zavodna, M.; Compton, S.G.; Gilmartin, P.M.
2005-01-01
Quantitative tests of sex allocation theory have often indicated that organism strategies deviate from model predictions. In pollinating fig wasps, Lipporrhopalum tentacularis, whole fig (brood) sex ratios are generally more female-biased than predicted by local mate competition (LMC) theory where f
A correlational study of scoliosis and trunk balance in adult patients with mandibular deviation.
Zhou, Shuncheng; Yan, Juanjuan; Da, Hu; Yang, Yang; Wang, Na; Wang, Wenyong; Ding, Yin; Sun, Shiyao
2013-01-01
Previous studies have confirmed that patients with mandibular deviation often have abnormal morphology of their cervical vertebrae. However, the relationship between mandibular deviation, scoliosis, and trunk balance has not been studied. Currently, mandibular deviation is usually treated as a single pathology, which leads to poor clinical efficiency. We investigated the relationship of spine coronal morphology and trunk balance in adult patients with mandibular deviation, and compared the finding to those in healthy volunteers. 35 adult patients with skeletal mandibular deviation and 10 healthy volunteers underwent anterior X-ray films of the head and posteroanterior X-ray films of the spine. Landmarks and lines were drawn and measured on these films. The axis distance method was used to measure the degree of scoliosis and the balance angle method was used to measure trunk balance. The relationship of mandibular deviation, spine coronal morphology and trunk balance was evaluated with the Pearson correlation method. The spine coronal morphology of patients with mandibular deviation demonstrated an "S" type curve, while a straight line parallel with the gravity line was found in the control group (significant difference, pbalance of patients with mandibular deviation was disturbed (imbalance angle >1°), while the control group had a normal trunk balance (imbalance angle <1°). There was a significant difference between the two groups (p<0.01). The degree of scoliosis and shoulder imbalance correlated with the degree of mandibular deviation, and presented a linear trend. The direction of mandibular deviation was the same as that of the lateral bending of thoracolumbar vertebrae, which was opposite to the direction of lateral bending of cervical vertebrae. Our study shows the degree of mandibular deviation has a high correlation with the degree of scoliosis and trunk imbalance, all the three deformities should be clinically evaluated in the management of mandibular
A Hybrid Joint Moment Ratio Test for Financial Time Series
Groenendijk, Patrick A.; Lucas, André; Vries, de Casper G.
1998-01-01
We advocate the use of absolute moment ratio statistics in conjunctionwith standard variance ratio statistics in order to disentangle lineardependence, non-linear dependence, and leptokurtosis in financial timeseries. Both statistics are computed for multiple return horizonssimultaneously, and the
A Hybrid Joint Moment Ratio Test for Financial Time Series
Groenendijk, Patrick A.; Lucas, André; Vries, de Casper G.
1998-01-01
We advocate the use of absolute moment ratio statistics in conjunctionwith standard variance ratio statistics in order to disentangle lineardependence, non-linear dependence, and leptokurtosis in financial timeseries. Both statistics are computed for multiple return horizonssimultaneously, and the r
An Analysis of the Linguistic Deviation in Chapter X of Oliver Twist
刘聪
2013-01-01
Charles Dickens is one of the greatest critical realist writers of the Victorian Age. In language, he is often compared with William Shakespeare for his adeptness with the vernacular and large vocabulary. Charles Dickens achieved a recognizable place among English writers through the use of the stylistic features in his fictional language. Oliver Twist is the best representative of Charles Dickens’style, which makes it the most appropriate choice for the present stylistic study on Charles Dickens. No one who has ever read the dehumanizing workhouse scenes of Oliver Twist and the dark, criminal underworld life can forget them. This thesis attempts to investigate Oliver Twist through the approach of modern stylistics, particularly the theory of linguistic devia-tion. This thesis consists of an introduction, the main body and a conclusion. The introduction offers a brief summary of the com-ments on Charles Dickens and Chapter X of Oliver Twist, introduces the newly rising linguistic deviation theories, and brings about the theories on which this thesis settles. The main body explores the deviation effects produced from four aspects: lexical deviation, grammatical deviation, graphological deviation, and semantic deviation. It endeavors to show Dickens ’manipulating language and the effects achieved through this manipulation. The conclusion mainly sums up the previous analysis, and reveals the theme of the novel, positive effect of linguistic deviation and significance of deviation application.
Search for Standard Model Higgs boson in H → τ+τ− decay with the ATLAS detector
Nakamura Koji
2013-05-01
Full Text Available A search for the Standard Model (SM Higgs boson decaying into a pair of τ leptons is presented. The results are based on data samples of proton-proton collisions accumulated by ATLAS experiment at the LHC and corresponding to integrated luminosities of 4.6 fb−1 and 13.0 fb−1 at center-of-mass energies of √s = 7 TeV and 8 TeV, respectively. The observed (expected upper limit at 95% C.L. on the cross-section times the branching ratio for SM H → τ+τ− is found to be 1.9 (1.2 times the SM prediction for a Higgs boson with mass mH = 125 GeV. For this mass the observed (expected deviation from the background-only hypothesis corresponds to a local significance of 1.1 (1.7 standard deviations.
Svendsen, Anders Jørgen; Holmskov, U; Bro, Peter
1995-01-01
hitherto unnoted differences between controls and patients with either rheumatoid arthritis or systemic lupus erythematosus. For this we use simple, but unconventional, graphic representations of the data, based on difference plots and ratio plots. Differences between patients with Burkitt's lymphoma...... and systemic lupus erythematosus from another previously published study (Macanovic, M. and Lachmann, P.J. (1979) Clin. Exp. Immunol. 38, 274) are also represented using ratio plots. Our observations indicate that analysis by regression analysis may often be misleading....
Appert
2000-02-01
It has been recently conjectured that for large systems, the shape of the central part of the large deviation function of the growth velocity would be universal for all the growth systems described by the Kardar-Parisi-Zhang equation in 1+1 dimension. One signature of this universality would be that the ratio of cumulants R(t)=[(c)](2)/[(c)(c)] would tend towards a universal value 0.415 17ellipsis as t tends to infinity, provided periodic boundary conditions are used. This has recently been questioned by Stauffer. In this paper we summarize various numerical and analytical results supporting this conjecture, and report in particular some numerical measurements of the ratio R(t) for the Eden model.
Asaranti Kar
2015-01-01
Full Text Available Introduction: Neural tube defects (NTD are a group of serious birth defects occurring due to defective closure of neural tube during embryonic development. It comprises of anencephaly, encephalocele and spina bifida. We conducted this prospective fetal autopsy series to study the rate and distribution of NTD, analyze the reproductive factors and risk factors, note any associated anomalies and evaluate the organ weights and their deviation from normal. Materials and Methods: This was a prospective study done over a period of 6 years from August, 2007 to July, 2013. All cases of NTDs delivered as abortion, still born and live born were included. The reproductive and risk factors like age, parity, multiple births, previous miscarriage, obesity, diabetes mellitus, socioeconomic status and use of folic acid during pregnancy were collected.Autopsy was performed according to Virchow′s technique. Detail external and internal examination were carried out to detect any associated anomalies. Gross and microscopic examination of organs were done. Results: Out of 210 cases of fetal and perinatal autopsy done, 72 (34.28% had NTD constituting 49 cases of anencephaly, 16 spina bifida and 7 cases of encephalocele. The mothers in these cases predominantly were within 25-29 years (P = 0.02 and primy (P = 0.01. Female sex was more commonly affected than males (M:F = 25:47, P = 0.0005 There was no history of folate use in majority of cases. Organ weight deviations were >2 standard deviation low in most of the cases. Most common associated anomalies were adrenal hypoplasia and thymic hyperplasia. Conclusion: The authors have made an attempt to study NTD cases in respect to maternal reproductive and risk factors and their association with NTD along with the organ weight deviation and associated anomalies. This so far in our knowledge is an innovative study which was not found in literature even after extensive search.
Griffin, James M.; Diaz, Fernanda; Geerling, Edgar; Clasing, Matias; Ponce, Vicente; Taylor, Chris; Turner, Sam; Michael, Ernest A.; Patricio Mena, F.; Bronfman, Leonardo
2017-02-01
By using acoustic emission (AE) it is possible to control deviations and surface quality during micro milling operations. The method of micro milling is used to manufacture a submillimetre waveguide where micro machining is employed to achieve the required superior finish and geometrical tolerances. Submillimetre waveguide technology is used in deep space signal retrieval where highest detection efficiencies are needed and therefore every possible signal loss in the receiver has to be avoided and stringent tolerances achieved. With a sub-standard surface finish the signals travelling along the waveguides dissipate away faster than with perfect surfaces where the residual roughness becomes comparable with the electromagnetic skin depth. Therefore, the higher the radio frequency the more critical this becomes. The method of time-frequency analysis (STFT) is used to transfer raw AE into more meaningful salient signal features (SF). This information was then correlated against the measured geometrical deviations and, the onset of catastrophic tool wear. Such deviations can be offset from different AE signals (different deviations from subsequent tests) and feedback for a final spring cut ensuring the geometrical accuracies are met. Geometrical differences can impact on the required transfer of AE signals (change in cut off frequencies and diminished SNR at the interface) and therefore errors have to be minimised to within 1 μm. Rules based on both Classification and Regression Trees (CART) and Neural Networks (NN) were used to implement a simulation displaying how such a control regime could be used as a real time controller, be it corrective measures (via spring cuts) over several initial machining passes or, with a micron cut introducing a level plain measure for allowing setup corrective measures (similar to a spirit level).
Graphene Nanogrids FET Immunosensor: Signal to Noise Ratio Enhancement
Jayeeta Basu
2016-10-01
Full Text Available Recently, a reproducible and scalable chemical method for fabrication of smooth graphene nanogrids has been reported which addresses the challenges of graphene nanoribbons (GNR. These nanogrids have been found to be capable of attomolar detection of biomolecules in field effect transistor (FET mode. However, for detection of sub-femtomolar concentrations of target molecule in complex mixtures with reasonable accuracy, it is not sufficient to only explore the steady state sensitivities, but is also necessary to investigate the flicker noise which dominates at frequencies below 100 kHz. This low frequency noise is dependent on the exposure time of the graphene layer in the buffer solution and concentration of charged impurities at the surface. In this paper, the functionalization strategy of graphene nanogrids has been optimized with respect to concentration and incubation time of the cross linker for an enhancement in signal to noise ratio (SNR. It has been interestingly observed that as the sensitivity and noise power change at different rates with the functionalization parameters, SNR does not vary monotonically but is maximum corresponding to a particular parameter. The optimized parameter has improved the SNR by 50% which has enabled a detection of 0.05 fM Hep-B virus molecules with a sensitivity of around 30% and a standard deviation within 3%. Further, the SNR enhancement has resulted in improvement of quantification accuracy by five times and selectivity by two orders of magnitude.
Constrained variability of modeled T:ET ratio across biomes
Fatichi, Simone; Pappas, Christoforos
2017-07-01
A large variability (35-90%) in the ratio of transpiration to total evapotranspiration (referred here as T:ET) across biomes or even at the global scale has been documented by a number of studies carried out with different methodologies. Previous empirical results also suggest that T:ET does not covary with mean precipitation and has a positive dependence on leaf area index (LAI). Here we use a mechanistic ecohydrological model, with a refined process-based description of evaporation from the soil surface, to investigate the variability of T:ET across biomes. Numerical results reveal a more constrained range and higher mean of T:ET (70 ± 9%, mean ± standard deviation) when compared to observation-based estimates. T:ET is confirmed to be independent from mean precipitation, while it is found to be correlated with LAI seasonally but uncorrelated across multiple sites. Larger LAI increases evaporation from interception but diminishes ground evaporation with the two effects largely compensating each other. These results offer mechanistic model-based evidence to the ongoing research about the patterns of T:ET and the factors influencing its magnitude across biomes.
Measurement of the Atmospheric Muon Charge Ratio at TeV Energies with MINOS
Adamson, P; Arms, K E; Armstrong, R; Auty, D J; Avvakumov, S; Ayres, D S; Baller, B; Barish, B; Barnes, P D; Barr, G; Barrett, W L; Beall, E; Becker, B R; Belias, A; Bergfeld, T; Bernstein, R H; Bhattacharya, D; Bishai, M; Blake, A; Bock, B; Bock, G J; Böhm, J; Böhnlein, D J; Bogert, D; Border, P M; Bower, C; Buckley-Geer, E; Bungau, C; Cabrera, A; Chapman, J D; Cherdack, D; Childress, S; Choudhary, B C; Cobb, J H; Culling, A J; De Jong, J K; De Santo, A; Dierckxsens, M; Diwan, M V; Dorman, M; Drakoulakos, D; Durkin, T; Erwin, A R; Escobar, C O; Evans, J J; Falk-Harris, E; Feldman, G J; Fields, T H; Ford, R; Frohne, M V; Gallagher, H R; Giurgiu, G A; Godley, A; Gogos, J; Goodman, M C; Gouffon, P; Gran, R; Grashorn, E W; Grossman, N; Grzelak, K; Habig, A; Harris, D; Harris, P G; Hartnell, J; Hartouni, E P; Hatcher, R; Heller, K; Holin, A; Howcroft, C; Hylen, J; Indurthy, D; Irwin, G M; Ishitsuka, M; Jaffe, D E; James, C; Jenner, L; Jensen, D; Joffe-Minor, T; Kafka, T; Kang, H J; Kasahara, S M S; Kim, M S; Koizumi, G; Kopp, S; Kordosky, M; Koskinen, D J; Kotelnikov, S K; Kreymer, A; Kumaratunga, S; Lang, K; Lebedev, A; Lee, R; Ling, J; Liu, J; Litchfield, P J; Litchfield, R P; Lucas, P; Mann, W A; Marchionni, A; Marino, A D; Marshak, M L; Marshall, J S; Mayer, N; McGowan, A M; Meier, J R; Merzon, G I; Messier, M D; Michael, D G; Milburn, R H; Miller, J L; Miller, W H; Mishra, S R; Mislivec, A; Miyagawa, P S; Moore, C D; Morfin, J; Mualem, L; Mufson, S; Murgia, S; Musser, J; Naples, D; Nelson, J K; Newman, H B; Nichol, R J; Nicholls, T C; Ochoa-Ricoux, J P; Oliver, W P; Osiecki, T; Ospanov, R; Paley, J; Paolone, V; Para, A; Patzak, T; Pavlovic, Z; Pearce, G F; Peck, C W; Peterson, E A; Petyt, D A; Ping, H; Piteira, R; Pittam, R; Plunkett, R K; Rahman, D; Rameika, R A; Raufer, T M; Rebel, B; Reichenbacher, J; Reyna, D E; Rosenfeld, C; Rubin, H A; Ruddick, K; Ryabov, V A; Saakyan, R; Sanchez, M C; Saoulidou, N; Schneps, J; Schreiner, P; Semenov, V K; Seun, S M; Shanahan, P; Smart, W; Smirnitsky, V; Smith, C; Sousa, A; Speakman, B; Stamoulis, P; Symes, P A; Tagg, N; Talaga, R L; Tetteh-Lartey, E; Thomas, J; Thompson, J; Thomson, M A; Thron, J L; Tinti, G; Trostin, I; Tsarev, V A; Tzanakos, G; Urheim, J; Vahle, P; Velissaris, C; Verebryusov, V; Viren, B; Ward, C P; Ward, D R; Watabe, M; Weber, A; Webb, R C; Wehmann, A; West, N; White, C; Wojcicki, S G; Wright, D M; Wu, Q K; Yang, T; Yumiceva, F X; Zheng, H; Zois, M; Zwaska, R
2007-01-01
The 5.4 kton MINOS far detector has been taking charge-separated cosmic ray muon data since the beginning of August, 2003 at a depth of 2070 meters-water-equivalent in the Soudan Underground Laboratory, Minnesota, USA. The data with both forward and reversed magnetic field running configurations were combined to minimize systematic errors in the determination of the underground muon charge ratio. When averaged, two independent analyses find the charge ratio underground to be 1.374 +/- 0.004 (stat.) +0.012 -0.010(sys.). Using the map of the Soudan rock overburden, the muon momenta as measured underground were projected to the corresponding values at the surface in the energy range 1-7 TeV. Within this range of energies at the surface, the MINOS data are consistent with the charge ratio being energy independent at the two standard deviation level. When the MINOS results are compared with measurements at lower energies, a clear rise in the charge ratio in the energy range 0.3 -- 1.0 TeV is apparent. A qualitativ...
A correlational study of scoliosis and trunk balance in adult patients with mandibular deviation.
Shuncheng Zhou
Full Text Available Previous studies have confirmed that patients with mandibular deviation often have abnormal morphology of their cervical vertebrae. However, the relationship between mandibular deviation, scoliosis, and trunk balance has not been studied. Currently, mandibular deviation is usually treated as a single pathology, which leads to poor clinical efficiency. We investigated the relationship of spine coronal morphology and trunk balance in adult patients with mandibular deviation, and compared the finding to those in healthy volunteers. 35 adult patients with skeletal mandibular deviation and 10 healthy volunteers underwent anterior X-ray films of the head and posteroanterior X-ray films of the spine. Landmarks and lines were drawn and measured on these films. The axis distance method was used to measure the degree of scoliosis and the balance angle method was used to measure trunk balance. The relationship of mandibular deviation, spine coronal morphology and trunk balance was evaluated with the Pearson correlation method. The spine coronal morphology of patients with mandibular deviation demonstrated an "S" type curve, while a straight line parallel with the gravity line was found in the control group (significant difference, p1°, while the control group had a normal trunk balance (imbalance angle <1°. There was a significant difference between the two groups (p<0.01. The degree of scoliosis and shoulder imbalance correlated with the degree of mandibular deviation, and presented a linear trend. The direction of mandibular deviation was the same as that of the lateral bending of thoracolumbar vertebrae, which was opposite to the direction of lateral bending of cervical vertebrae. Our study shows the degree of mandibular deviation has a high correlation with the degree of scoliosis and trunk imbalance, all the three deformities should be clinically evaluated in the management of mandibular deviation.
Christensen, Ole Fredslund; Frydenberg, Morten; Jensen, Jens Ledet
2005-01-01
The large deviation modified likelihood ratio statistic is studied for testing a variance component equal to a specified value. Formulas are presented in the general balanced case, whereas in the unbalanced case only the one-way random effects model is studied. Simulation studies are presented, s......, showing that the normal approximation to the large deviation modified likelihood ratio statistic gives confidence intervals for variance components with coverage probabilities very close to the nominal confidence coefficient....
Measurement of the branching ratio of $\\bar{B} \\to D^{(\\ast)} \\tau^- \\bar{\
Huschle, M; Heck, M; Goldenzweig, P; Abdesselam, A; Adachi, I; Adamczyk, K; Aihara, H; Said, S Al; Arinstein, K; Asner, D M; Aushev, T; Ayad, R; Aziz, T; Badhrees, I; Bakich, A M; Bansal, V; Barberio, E; Bhardwaj, V; Bhuyan, B; Biswal, J; Bobrov, A; Bozek, A; Bračko, M; Browder, T E; Červenkov, D; Chang, P; Chekelian, V; Chen, A; Cheon, B G; Chilikin, K; Chistov, R; Cho, K; Chobanova, V; Choi, Y; Cinabro, D; Dalseno, J; Danilov, M; Doležal, Z; Drásal, Z; Dutta, D; Eidelman, S; Epifanov, D; Farhat, H; Fast, J E; Ferber, T; Frey, A; Fulsom, B G; Gaur, V; Gabyshev, N; Garmash, A; Gillard, R; Glattauer, R; Goh, Y M; Golob, B; Grygier, J; Hamer, P; Hara, K; Hara, T; Hasenbusch, J; Hayasaka, K; Hayashii, H; He, X H; Heider, M; Heller, A; Horiguchi, T; Hou, W -S; Hsu, C -L; Iijima, T; Inami, K; Inguglia, G; Ishikawa, A; Itoh, R; Iwasaki, Y; Jaegle, I; Joffe, D; Joo, K K; Julius, T; Kang, K H; Kato, E; Katrenko, P; Kawasaki, T; Keck, T; Kiesling, C; Kim, D Y; Kim, H J; Kim, J B; Kim, J H; Kim, K T; Kim, M J; Kim, S H; Kim, Y J; Kinoshita, K; Ko, B R; Kobayashi, N; Kodyš, P; Korpar, S; Križan, P; Krokovny, P; Kumita, T; Kuzmin, A; Kwon, Y -J; Lee, I S; Li, C; Li, Y; Gioi, L Li; Libby, J; Liventsev, D; Lukin, P; Masuda, M; Matvienko, D; Miyabayashi, K; Miyake, H; Miyata, H; Mizuk, R; Mohanty, G B; Mohanty, S; Moll, A; Moon, H K; Mussa, R; Nakamura, K R; Nakano, E; Nakao, M; Nanut, T; Nayak, M; Nisar, N K; Nishida, S; Ogawa, S; Okuno, S; Oswald, C; Pakhlova, G; Pal, B; Park, C W; Park, H; Pedlar, T K; Pesántez, L; Pestotnik, R; Petrič, M; Piilonen, L E; Pulvermacher, C; Ribežl, E; Ritter, M; Rostomyan, A; Sakai, Y; Sandilya, S; Santelj, L; Sanuki, T; Sato, Y; Savinov, V; Schneider, O; Schnell, G; Schwanda, C; Schwartz, A J; Semmler, D; Senyo, K; Seon, O; Sevior, M E; Shebalin, V; Shen, C P; Shibata, T -A; Shiu, J -G; Simon, F; Sohn, Y -S; Sokolov, A; Solovieva, E; Stanič, S; Starič, M; Steder, M; Stypula, J; Sumihama, M; Sumiyoshi, T; Tamponi, U; Teramoto, Y; Trabelsi, K; Trusov, V; Uchida, M; Uglov, T; Uno, S; Usov, Y; Van Hulse, C; Vanhoefer, P; Varner, G; Vinokurova, A; Vorobyev, V; Wagner, M N; Wang, C H; Wang, M -Z; Wang, P; Wang, X L; Watanabe, M; Watanabe, Y; Won, E; Yamamoto, H; Yamaoka, J; Yashchenko, S; Ye, H; Yook, Y; Yuan, C Z; Yusa, Y; Zhang, Z P; Zhilich, V; Zhulanov, V; Zupanc, A
2015-01-01
We report a measurement of the branching fraction ratios R(D(*)) of Bbar -> D(*) tau- nubar_tau relative to Bbar -> D()* l- nubar_l (where l = e or mu) using the full Belle data sample of 772 x 10^6 BBbar pairs collected at the Y(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. The measured values are R(D)= 0.375 +- 0.064(stat.) +- 0.026(syst.) and R(D*) = 0.293 +- 0.038(stat.) +- 0.015(syst.). The analysis uses hadronic reconstruction of the tag-side B meson and purely leptonic tau decays. The results are consistent with earlier measurements and do not show a significant deviation from the standard model prediction.
Young, Virginia R
2007-01-01
We develop a pricing rule for life insurance under stochastic mortality in an incomplete market by assuming that the insurance company requires compensation for its risk in the form of a pre-specified instantaneous Sharpe ratio. Our valuation formula satisfies a number of desirable properties, many of which it shares with the standard deviation premium principle. The major result of the paper is that the price per contract solves a linear partial differential equation as the number of contracts approaches infinity. One can interpret the limiting price as an expectation with respect to an equivalent martingale measure. Another important result is that if the hazard rate is stochastic, then the risk-adjusted premium is greater than the net premium, even as the number of contracts approaches infinity. We present a numerical example to illustrate our results, along with the corresponding algorithms.
First observation of the decay Bs0-->Ds-Ds+ and measurement of its branching ratio.
Aaltonen, T; Adelman, J; Akimoto, T; Albrow, M G; Alvarez González, B; Amerio, S; Amidei, D; Anastassov, A; Annovi, A; Antos, J; Aoki, M; Apollinari, G; Apresyan, A; Arisawa, T; Artikov, A; Ashmanskas, W; Attal, A; Aurisano, A; Azfar, F; Azzi-Bacchetta, P; Azzurri, P; Bacchetta, N; Badgett, W; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Baroiant, S; Bartsch, V; Bauer, G; Beauchemin, P-H; Bedeschi, F; Bednar, P; Behari, S; Bellettini, G; Bellinger, J; Belloni, A; Benjamin, D; Beretvas, A; Beringer, J; Berry, T; Bhatti, A; Binkley, M; Bisello, D; Bizjak, I; Blair, R E; Blocker, C; Blumenfeld, B; Bocci, A; Bodek, A; Boisvert, V; Bolla, G; Bolshov, A; Bortoletto, D; Boudreau, J; Boveia, A; Brau, B; Bridgeman, A; Brigliadori, L; Bromberg, C; Brubaker, E; Budagov, J; Budd, H S; Budd, S; Burkett, K; Busetto, G; Bussey, P; Buzatu, A; Byrum, K L; Cabrera, S; Campanelli, M; Campbell, M; Canelli, F; Canepa, A; Carlsmith, D; Carosi, R; Carrillo, S; Carron, S; Casal, B; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavalli-Sforza, M; Cerri, A; Cerrito, L; Chang, S H; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Chlebana, F; Cho, K; Chokheli, D; Chou, J P; Choudalakis, G; Chuang, S H; Chung, K; Chung, W H; Chung, Y S; Ciobanu, C I; Ciocci, M A; Clark, A; Clark, D; Compostella, G; Convery, M E; Conway, J; Cooper, B; Copic, K; Cordelli, M; Cortiana, G; Crescioli, F; Cuenca Almenar, C; Cuevas, J; Culbertson, R; Cully, J C; Dagenhart, D; Datta, M; Davies, T; de Barbaro, P; De Cecco, S; Deisher, A; De Lentdecker, G; De Lorenzo, G; Dell'Orso, M; Demortier, L; Deng, J; Deninno, M; De Pedis, D; Derwent, P F; Di Giovanni, G P; Dionisi, C; Di Ruzza, B; Dittmann, J R; D'Onofrio, M; Donati, S; Dong, P; Donini, J; Dorigo, T; Dube, S; Efron, J; Erbacher, R; Errede, D; Errede, S; Eusebi, R; Fang, H C; Farrington, S; Fedorko, W T; Feild, R G; Feindt, M; Fernandez, J P; Ferrazza, C; Field, R; Flanagan, G; Forrest, R; Forrester, S; Franklin, M; Freeman, J C; Furic, I; Gallinaro, M; Galyardt, J; Garberson, F; Garcia, J E; Garfinkel, A F; Gerberich, H; Gerdes, D; Giagu, S; Giakoumopolou, V; Giannetti, P; Gibson, K; Gimmell, J L; Ginsburg, C M; Giokaris, N; Giordani, M; Giromini, P; Giunta, M; Glagolev, V; Glenzinski, D; Gold, M; Goldschmidt, N; Golossanov, A; Gomez, G; Gomez-Ceballos, G; Goncharov, M; González, O; Gorelov, I; Goshaw, A T; Goulianos, K; Gresele, A; Grinstein, S; Grosso-Pilcher, C; Grundler, U; Guimaraes da Costa, J; Gunay-Unalan, Z; Haber, C; Hahn, K; Hahn, S R; Halkiadakis, E; Hamilton, A; Han, B-Y; Han, J Y; Handler, R; Happacher, F; Hara, K; Hare, D; Hare, M; Harper, S; Harr, R F; Harris, R M; Hartz, M; Hatakeyama, K; Hauser, J; Hays, C; Heck, M; Heijboer, A; Heinemann, B; Heinrich, J; Henderson, C; Herndon, M; Heuser, J; Hewamanage, S; Hidas, D; Hill, C S; Hirschbuehl, D; Hocker, A; Hou, S; Houlden, M; Hsu, S-C; Huffman, B T; Hughes, R E; Husemann, U; Huston, J; Incandela, J; Introzzi, G; Iori, M; Ivanov, A; Iyutin, B; James, E; Jayatilaka, B; Jeans, D; Jeon, E J; Jindariani, S; Johnson, W; Jones, M; Joo, K K; Jun, S Y; Jung, J E; Junk, T R; Kamon, T; Kar, D; Karchin, P E; Kato, Y; Kephart, R; Kerzel, U; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kimura, N; Kirsch, L; Klimenko, S; Klute, M; Knuteson, B; Ko, B R; Koay, S A; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kraus, J; Kreps, M; Kroll, J; Krumnack, N; Kruse, M; Krutelyov, V; Kubo, T; Kuhlmann, S E; Kuhr, T; Kulkarni, N P; Kusakabe, Y; Kwang, S; Laasanen, A T; Lai, S; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; Lecompte, T; Lee, J; Lee, J; Lee, Y J; Lee, S W; Lefèvre, R; Leonardo, N; Leone, S; Levy, S; Lewis, J D; Lin, C; Lin, C S; Linacre, J; Lindgren, M; Lipeles, E; Lister, A; Litvintsev, D O; Liu, T; Lockyer, N S; Loginov, A; Loreti, M; Lovas, L; Lu, R-S; Lucchesi, D; Lueck, J; Luci, C; Lujan, P; Lukens, P; Lungu, G; Lyons, L; Lys, J; Lysak, R; Lytken, E; Mack, P; Macqueen, D; Madrak, R; Maeshima, K; Makhoul, K; Maki, T; Maksimovic, P; Malde, S; Malik, S; Manca, G; Manousakis, A; Margaroli, F; Marino, C; Marino, C P; Martin, A; Martin, M; Martin, V; Martínez, M; Martínez-Ballarín, R; Maruyama, T; Mastrandrea, P; Masubuchi, T; Mattson, M E; Mazzanti, P; McFarland, K S; McIntyre, P; McNulty, R; Mehta, A; Mehtala, P; Menzemer, S; Menzione, A; Merkel, P; Mesropian, C; Messina, A; Miao, T; Miladinovic, N; Miles, J; Miller, R; Mills, C; Milnik, M; Mitra, A; Mitselmakher, G; Miyake, H; Moed, S; Moggi, N; Moon, C S; Moore, R; Morello, M; Movilla Fernandez, P; Mülmenstädt, J; Mukherjee, A; Muller, Th; Mumford, R; Murat, P; Mussini, M; Nachtman, J; Nagai, Y; Nagano, A; Naganoma, J; Nakamura, K; Nakano, I; Napier, A; Necula, V; Neu, C; Neubauer, M S; Nielsen, J; Nodulman, L; Norman, M; Norniella, O; Nurse, E; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Oldeman, R; Orava, R; Osterberg, K; Pagan Griso, S; Pagliarone, C; Palencia, E; Papadimitriou, V; Papaikonomou, A; Paramonov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Pellett, D E; Penzo, A; Phillips, T J; Piacentino, G; Piedra, J; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Portell, X; Poukhov, O; Pounder, N; Prakoshyn, F; Pronko, A; Proudfoot, J; Ptohos, F; Punzi, G; Pursley, J; Rademacker, J; Rahaman, A; Ramakrishnan, V; Ranjan, N; Redondo, I; Reisert, B; Rekovic, V; Renton, P; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robson, A; Rodrigo, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Roy, P; Ruiz, A; Russ, J; Rusu, V; Saarikko, H; Safonov, A; Sakumoto, W K; Salamanna, G; Saltó, O; Santi, L; Sarkar, S; Sartori, L; Sato, K; Savoy-Navarro, A; Scheidle, T; Schlabach, P; Schmidt, E E; Schmidt, M A; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scott, A L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sfyria, A; Shalhout, S Z; Shapiro, M D; Shears, T; Shepard, P F; Sherman, D; Shimojima, M; Shochet, M; Shon, Y; Shreyber, I; Sidoti, A; Sinervo, P; Sisakyan, A; Slaughter, A J; Slaunwhite, J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Soderberg, M; Soha, A; Somalwar, S; Sorin, V; Spalding, J; Spinella, F; Spreitzer, T; Squillacioti, P; Stanitzki, M; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Stuart, D; Suh, J S; Sukhanov, A; Sun, H; Suslov, I; Suzuki, T; Taffard, A; Takashima, R; Takeuchi, Y; Tanaka, R; Tecchio, M; Teng, P K; Terashi, K; Thom, J; Thompson, A S; Thompson, G A; Thomson, E; Tipton, P; Tiwari, V; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Tourneur, S; Trischuk, W; Tu, Y; Turini, N; Ukegawa, F; Uozumi, S; Vallecorsa, S; van Remortel, N; Varganov, A; Vataga, E; Vázquez, F; Velev, G; Vellidis, C; Veszpremi, V; Vidal, M; Vidal, R; Vila, I; Vilar, R; Vine, T; Vogel, M; Volobouev, I; Volpi, G; Würthwein, F; Wagner, P; Wagner, R G; Wagner, R L; Wagner-Kuhr, J; Wagner, W; Wakisaka, T; Wallny, R; Wang, S M; Warburton, A; Waters, D; Weinberger, M; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Wynne, S M; Yagil, A; Yamamoto, K; Yamaoka, J; Yamashita, T; Yang, C; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zaw, I; Zhang, X; Zheng, Y; Zucchelli, S
2008-01-18
We report the observation of the exclusive decay Bs0-->Ds-Ds+ at the 7.5 standard deviation level using 355 pb(-1) of data collected by the CDF II detector in pp collisions at sqrt[s]=1.96 TeV at the Fermilab Tevatron. We measure the relative branching ratio B(Bs0-->Ds-Ds+)/B(B0-->D-Ds+)=1.44(-0.44)(+0.48). Using the world average value for B(B0-->D-Ds+), we find B(Bs0-->Ds-Ds+)=(9.4(-4.2)(+4.4))x10(-3). This provides a lower bound DeltaGammasCP/Gammas>or=2B(Bs0-->Ds-Ds+)>1.2x10(-2) at 95% C.L.
Large Deviations for Parameter Estimators of Some Time Inhomogeneous Diffusion Process
Shou Jiang ZHAO; Fu Qing GAO
2011-01-01
The goal of this paper is to study large deviations for estimator and score function of some time inhomogeneous diffusion process.Large deviation in the non-steepness case with explicit rate functions is obtained by using parameter-dependent change of measure.
Moderate Deviations for M-estimators in Linear Models with φ-mixing Errors
Jun FAN
2012-01-01
In this paper,the moderate deviations for the M-estimators of regression parameter in a linear model are obtained when the errors form a strictly stationary φ-mixing sequence.The results are applied to study many different types of M-estimators such as Huber's estimator,Lp-regression estimator,least squares estimator and least absolute deviation estimator.
Yi Wen JIANG; Li Ming WU
2005-01-01
All known results on large deviations of occupation measures of Markov processes are based on the assumption of (essential) irreducibility. In this paper we establish the weak* large deviation principle of occupation measures for any countable Markov chain with arbitrary initial measures. The new rate function that we obtain is not convex and depends on the initial measure, contrary to the (essentially) irreducible case.
Dynamical Gibbs-non-Gibbs transitions : a study via coupling and large deviations
Wang, Feijia
2012-01-01
In this thesis we use both the two-layer and the large-deviation approach to study the conservation and loss of the Gibbs property for both lattice and mean-field spin systems. Chapter 1 gives general backgrounds on Gibbs and non-Gibbs measures and outlines the the two-layer and the large-deviation
Litvin, Faydor L.; Kuan, Chihping; Zhang, YI
1991-01-01
A numerical method is developed for the minimization of deviations of real tooth surfaces from the theoretical ones. The deviations are caused by errors of manufacturing, errors of installment of machine-tool settings and distortion of surfaces by heat-treatment. The deviations are determined by coordinate measurements of gear tooth surfaces. The minimization of deviations is based on the proper correction of initially applied machine-tool settings. The contents of accomplished research project cover the following topics: (1) Descriptions of the principle of coordinate measurements of gear tooth surfaces; (2) Deviation of theoretical tooth surfaces (with examples of surfaces of hypoid gears and references for spiral bevel gears); (3) Determination of the reference point and the grid; (4) Determination of the deviations of real tooth surfaces at the points of the grid; and (5) Determination of required corrections of machine-tool settings for minimization of deviations. The procedure for minimization of deviations is based on numerical solution of an overdetermined system of n linear equations in m unknowns (m much less than n ), where n is the number of points of measurements and m is the number of parameters of applied machine-tool settings to be corrected. The developed approach is illustrated with numerical examples.
Zhong Hao XU; Dong HAN
2011-01-01
We model an epidemic with a class of nonhomogeneous Markov chains on the supercritical percolation network on Zd.The large deviations law for the Markov chain is given.Explicit expression of the rate function for large deviation is obtained.
On Translation of Language Deviation from the Perspective of Peter Newmark’s Translation Dichotomy
胡娜; 延宏
2016-01-01
Language deviation can bring fresh vitality to literary creation. In literary works translation,through adoption of proper translation strategies, the effects created by language deviation in the original text can be efficiently reproduced. Here, the writer attempts to make a narration and relevant analyses on it.
Large Deviations Methods and the Join-the-Shortest-Queue Model
Ridder, Ad; Shwartz, Adam
2005-01-01
We develop a methodology for studying ''large deviations type'' questions. Our approach does not require that the large deviations principle holds, and is thus applicable to a larg class of systems. We study a system of queues with exponential servers, which share an arrival stream. Arrivals are rou
2013-09-24
... Program; Single- Case Deviation From Competition Requirements AGENCY: Health Resources and Services Administration (HRSA), Department of Health and Human Services (HHS). ACTION: Notice of Single-Case Deviation... purpose to improve the health of all mothers and children, a key objective of the Title V MCH Block Grant...
Martya Rahmaniati; Tris Eryando; Dewi Susanna; Dian Pratiwi; Fajar Nugraha; Andri Ruliansah; Muhammad Umar Riandi
2014-01-01
Dengue Fever Disease is still regarded as an endemic disease in Banjar City. Information is still required to map dengue fever case distribution, mean center of case distribution, and the direction of dengue fever case dispersion in order to support the surveillance program in the relation to the vast area of the dengue fever disease control program. The objective of the research is to obtain information regarding the area of dengue fever disease distribution in Banjar City by utilizing the S...
Rodbard, David
2012-10-01
We describe a new approach to estimate the risks of hypo- and hyperglycemia based on the mean and SD of the glucose distribution using optional transformations of the glucose scale to achieve a more nearly symmetrical and Gaussian distribution, if necessary. We examine the correlation of risks of hypo- and hyperglycemia calculated using different glucose thresholds and the relationships of these risks to the mean glucose, SD, and percentage coefficient of variation (%CV). Using representative continuous glucose monitoring datasets, one can predict the risk of glucose values above or below any arbitrary threshold if the glucose distribution is Gaussian or can be transformed to be Gaussian. Symmetry and gaussianness can be tested objectively and used to optimize the transformation. The method performs well with excellent correlation of predicted and observed risks of hypo- or hyperglycemia for individual subjects by time of day or for a specified range of dates. One can compare observed and calculated risks of hypo- and hyperglycemia for a series of thresholds considering their uncertainties. Thresholds such as 80 mg/dL can be used as surrogates for thresholds such as 50 mg/dL. We observe a high correlation of risk of hypoglycemia with %CV and illustrate the theoretical basis for that relationship. One can estimate the historical risks of hypo- and hyperglycemia by time of day, date, day of the week, or range of dates, using any specified thresholds. Risks of hypoglycemia with one threshold (e.g., 80 mg/dL) can be used as an effective surrogate marker for hypoglycemia at other thresholds (e.g., 50 mg/dL). These estimates of risk can be useful in research studies and in the clinical care of patients with diabetes.
Salomons, E.M.; Janssen, S.A.; Verhagen, H.L.M.; Wessels, P.W.
2014-01-01
Annoyance and sleep disturbance by road and rail traffic noise in an urban area are investigated. Noise levels Lden and Lnight are determined with an engineering noise model that is optimized for the local situation, based on local noise measurements. The noise levels are combined with responses of
OPINIONSCONCERNINGTHE ORGANIZATIONOF STANDARD COSTS ACCOUNTANCY
Ion Ionescu
2015-10-01
Full Text Available The main purpose of this research is to present a way for organizing the accountancy under the conditions of applying the method of standard costs, such that to allow both the registration of standard and effective costs and the separate registration of the deviations from standard costs. Making some pertinent and performance decisions is mainly influenced by the quality of the information provided to managers and by the promptitude they are sent. This desiderate is not possible if using classical methods for calculating costs, reason for which it is mandatory to organize and implement a managerial accountancy, based on using a modern method, namely the method of standard costs. The main implications of this method consist of establishing a pertinent cost, orientated towards the entity management, regardless the activity domain where it is implemented. The carried out study concerns only one of the phases performed for applying the method of standard cost, respectively the organization of the standard costs accountancy.
Kjærgaard, Søren; Canudas-Romo, Vladimir
2017-01-01
, the prospective potential support ratio usually focuses on the current mortality schedule, or period life expectancy. Instead, in this paper we look at the actual mortality experienced by cohorts in a population, using cohort life tables. We analyse differences between the two perspectives using mortality models......, historical data, and forecasted data. Cohort life expectancy takes future mortality improvements into account, unlike period life expectancy, leading to a higher prospective potential support ratio. Our results indicate that using cohort instead of period life expectancy returns around 0.5 extra younger...
Sanfilippo, Paul G; Hammond, Christopher J; Staffieri, Sandra E; Kearns, Lisa S; Melissa Liew, S H; Barbour, Julie M; Hewitt, Alex W; Ge, Dongliang; Snieder, Harold; Mackinnon, Jane R; Brown, Shayne A; Lorenz, Birgit; Spector, Tim D; Martin, Nicholas G; Wilmer, Jeremy B; Mackey, David A
2012-10-01
Strabismus represents a complex oculomotor disorder characterized by the deviation of one or both eyes and poor vision. A more sophisticated understanding of the genetic liability of strabismus is required to guide searches for associated molecular variants. In this classical twin study of 1,462 twin pairs, we examined the relative influence of genes and environment in comitant strabismus, and the degree to which these influences can be explained by factors in common with refractive error. Participants were examined for the presence of latent ('phoria') and manifest ('tropia') strabismus using cover-uncover and alternate cover tests. Two phenotypes were distinguished: eso-deviation (esophoria and esotropia) and exo-deviation (exophoria and exotropia). Structural equation modeling was subsequently employed to partition the observed phenotypic variation in the twin data into specific variance components. The prevalence of eso-deviation and exo-deviation was 8.6% and 20.7%, respectively. For eso-deviation, the polychoric correlation was significantly greater in monozygotic (MZ) (r = 0.65) compared to dizygotic (DZ) twin pairs (r = 0.33), suggesting a genetic role (p = .003). There was no significant difference in polychoric correlation between MZ (r = 0.55) and DZ twin pairs (r = 0.53) for exo-deviation (p = .86), implying that genetic factors do not play a significant role in the etiology of exo-deviation. The heritability of an eso-deviation was 0.64 (95% CI 0.50-0.75). The additive genetic correlation for eso-deviation and refractive error was 0.13 and the bivariate heritability (i.e., shared variance) was less than 1%, suggesting negligible shared genetic effect. This study documents a substantial heritability of 64% for eso-deviation, yet no corresponding heritability for exo-deviation, suggesting that the genetic contribution to strabismus may be specific to eso-deviation. Future studies are now needed to identify the genes associated with eso-deviation and
[Down with odds ratios: risk ratios in cohort studies and randomised clinical trials].
Knol, Mirjam J
2012-01-01
Various effect measures are available for quantifying the relationship between an intervention or a risk factor and an outcome, such as the risk ratio and the odds ratio. Odds ratios are intended for use in case-control studies in which they are an appropriate measure for estimating the relative risk; however, this measure is also often presented in cohort studies and in randomized clinical trials. When used for cohort studies and randomized clinical trials, the odds ratio is often incorrectly interpreted as the risk ratio; the odds ratio then provides an overestimation of the risk ratio, especially when the outcome is frequent. The use of logistic regression to adjust for confounding is one of the reasons that odds ratios are presented. For cohort studies and randomized clinical trials, however, there are methods to estimate adjusted risk ratios; these include the Mantel-Haenszel method, log-binomial regression, Poisson regression with robust standard error, and 'doubling of cases' method with robust standard error. To avoid misinterpretation of odds ratios, risk ratios should be calculated in cohort studies and randomized clinical trials.
Deformation behavior of A6063 tube with initial thickness deviation in free hydraulic bulging
YANG Lian-fa; GUO Cheng; DENG Yang
2006-01-01
Experiment on seamless tubes of aluminum alloy A6063 with initial thickness deviation of 0-20% was conducted through a free hydraulic bulging with tube ends free. The influence of initial thickness deviation on the cross-section profile, thickness distribution, maximum internal pressure and maximum radial expansion was investigated. FEM simulation was also performed in order to examine and help explaining the experimental results. The results indicate that the internal pressure and maximum internal pressure appear to be little influenced by the initial thickness deviation, and that the cross-section profile of the bulged tube changes diversely and can not be a perfect circle. The results also suggest that the increase in initial thickness deviation may lead to a remarkable decrease in maximum radial expansion, and a rapid increase in thickness deviation and the center eccentricity of the inner and outer profiles.
The role of septal surgery in management of the deviated nose.
Foda, Hossam M T
2005-02-01
The deviated nose represents a complex cosmetic and functional problem. Septal surgery plays a central role in the successful management of the externally deviated nose. This study included 260 patients seeking rhinoplasty to correct external nasal deviations; 75 percent of them had various degrees of nasal obstruction. Septal surgery was necessary in 232 patients (89 percent), not only to improve breathing but also to achieve a straight, symmetrical, external nose as well. A graduated surgical approach was adopted to allow correction of the dorsal and caudal deviations of the nasal septum without weakening its structural support to the dorsum or nasal tip. The approach depended on full mobilization of deviated cartilage, followed by straightening of the cartilage and its fixation in the corrected position by using bony splinting grafts through an external rhinoplasty approach.
Bongiorno, C; Lillo, F; Mantegna, R N; Miccichè, S
2016-01-01
Understanding the relation between planned and realized flight trajectories and the determinants of flight deviations is of great importance in air traffic management. In this paper we perform an in depth investigation of the statistical properties of planned and realized air traffic on the German airspace during a 28 day periods, corresponding to an AIRAC cycle. We find that realized trajectories are on average shorter than planned ones and this effect is stronger during night-time than daytime. Flights are more frequently deviated close to the departure airport and at a relatively large angle to destination. Moreover, the probability of a deviation is higher in low traffic phases. All these evidences indicate that deviations are mostly used by controllers to give directs to flights when traffic conditions allow it. Finally we introduce a new metric, termed difork, which is able to characterize navigation points according to the likelihood that a deviation occurs there. Difork allows to identify in a statist...
Benkler, Erik; Sterr, Uwe
2015-01-01
The power spectral density in Fourier frequency domain, and the different variants of the Allan deviation (ADEV) in dependence on the averaging time are well established tools to analyse the fluctuation properties and frequency instability of an oscillatory signal. It is often supposed that the statistical uncertainty of a measured average frequency is given by the ADEV at a well considered averaging time. However, this approach requires further mathematical justification and refinement, which has already been done regarding the original ADEV for certain noise types. Here we provide the necessary background to use the modified Allan deviation (modADEV) and other two-sample deviations to determine the uncertainty of weighted frequency averages. The type of two-sample deviation used to determine the uncertainty depends on the method used for determination of the average. We find that the modADEV, which is connected with $\\Lambda$-weighted averaging, and the two sample deviation associated to a linear phase regr...
['Gold standard', not 'golden standard'
Claassen, J.A.H.R.
2005-01-01
In medical literature, both 'gold standard' and 'golden standard' are employed to describe a reference test used for comparison with a novel method. The term 'gold standard' in its current sense in medical research was coined by Rudd in 1979, in reference to the monetary gold standard. In the same w
['Gold standard', not 'golden standard'
Claassen, J.A.H.R.
2005-01-01
In medical literature, both 'gold standard' and 'golden standard' are employed to describe a reference test used for comparison with a novel method. The term 'gold standard' in its current sense in medical research was coined by Rudd in 1979, in reference to the monetary gold standard. In the same
USL/DBMS NASA/PC R and D project C programming standards
Dominick, Wayne D. (Editor); Moreau, Dennis R.
1984-01-01
A set of programming standards intended to promote reliability, readability, and portability of C programs written for PC research and development projects is established. These standards must be adhered to except where reasons for deviation are clearly identified and approved by the PC team. Any approved deviation from these standards must also be clearly documented in the pertinent source code.
Miles, T. R.; Haslum, M. N.; Wheeler, T. J.
1998-01-01
A study involving 11,804 British children (age 10) found that when specified criteria for dyslexia were used, 269 children qualified as dyslexic. These included 223 boys and 46 girls, for a ratio of 4.51 to 1. Difficulties in interpreting these data are discussed and a defense of the criteria is provided. (Author/CR)
PO de Wet
2005-06-01
Full Text Available The rectilinear Steiner ratio was shown to be 3/2 by Hwang [Hwang FK, 1976, On Steiner minimal trees with rectilinear distance, SIAM Journal on Applied Mathematics, 30, pp. 104– 114.]. We use continuity and introduce restricted point sets to obtain an alternative, short and self-contained proof of this result.
Baharoglu, Merih I; Lauric, Alexandra; Wu, Chengyuan; Hippelheuser, James; Malek, Adel M
2014-10-17
Cerebral aneurysms form preferentially at arterial bifurcations. The vascular optimality principle (VOP) decrees that minimal energy loss across bifurcations requires optimal caliber control between radii of parent (r₀) and daughter branches (r1 and r2): r₀(n)=r₁(n)+r₂(n), with n approximating three. VOP entails constant wall shear stress (WSS), an endothelial phenotype regulator. We sought to determine if caliber control is maintained in aneurysmal intracranial bifurcations. Three-dimensional rotational angiographic volumes of 159 middle cerebral artery (MCA) bifurcations (62 aneurysmal) were processed using 3D gradient edge-detection filtering, enabling threshold-insensitive radius measurement. Radius ratio (RR)=r₀(3)/(r₁(3)+r₂(3)) and estimated junction exponent (n) were compared between aneurysmal and non-aneurysmal bifurcations using Student t-test and Wilcoxon rank-sum analysis. The results show that non-aneurysmal bifurcations display optimal caliber control with mean RR of 1.05 and median n of 2.84. In contrast, aneurysmal bifurcations had significantly lower RR (0.76, pbifurcations revealed a daughter branch larger than its parent vessel, an absolute violation of optimality, not witnessed in non-aneurysmal bifurcations. The aneurysms originated more often off the smaller daughter (52%) vs. larger daughter branch (16%). Aneurysm size was not statistically correlated to RR or n. Aneurysmal males showed higher deviation from VOP. Non-aneurysmal MCA bifurcations contralateral to aneurysmal ones showed optimal caliber control. Aneurysmal bifurcations, in contrast to non-aneurysmal counterparts, disobey the VOP and may exhibit dysregulation in WSS-mediated caliber control. The mechanism of this focal divergence from optimality may underlie aneurysm pathogenesis and requires further study.
Stellinga, B.; Mügge, D.
2014-01-01
The European and global regulation of accounting standards have witnessed remarkable changes over the past twenty years. In the early 1990s, EU accounting practices were fragmented along national lines and US accounting standards were the de facto global standards. Since 2005, all EU listed companie
Rotator Cuff Strength Ratio and Injury in Glovebox Workers
Weaver, Amelia M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
2014-01-30
Rotator cuff integrity is critical to shoulder health. Due to the high workload imposed upon the shoulder while working in an industrial glovebox, this study investigated the strength ratio of the rotator cuff muscles in glovebox workers and compared this ratio to the healthy norm. Descriptive statistics were collected using a short questionnaire. Handheld dynamometry was used to quantify the ratio of forces produced in the motions of shoulder internal and external rotation. Results showed this population to have shoulder strength ratios that were significantly different from the healthy norm. The deviation from the normal ratio demonstrates the need for solutions designed to reduce the workload on the rotator cuff musculature of glovebox workers in order to improve health and safety. Assessment of strength ratios can be used to screen for risk of symptom development.
A contribution to large deviations for heavy-tailed random sums
SU; Chun
2001-01-01
［1］ Nagaev, A. V., Integral limit theorems for large deviations when Cramer's condition is not fulfilled I, II, Theory Prob. Appl., 1969, 14: 51-64, 193-208.［2］ Nagaev, A. V., Limit theorems for large deviations where Cramer's conditions are violated (In Russian), Izv. Akad. Nauk USSR Ser., Fiz-Mat Nauk., 1969, 7: 17.［3］ Heyde, C. C., A contribution to the theory of large deviations for sums of independent random variables, Z. Wahrscheinlichkeitsth, 1967, 7: 303.［4］ Heyde, C. C., On large deviation probabilities for sums of random variables which are not attracted to the normal law, Ann. Math. Statist., 1967, 38: 1575.［5］ Heyde, C. C., On large deviation probabilities in the case of attraction to a nonnormal stable law, Sanky, 1968, 30: 253.［6］ Nagaev, S. V., Large deviations for sums of independent random variables, in Sixth Prague Conf. on Information Theory, Random Processes and Statistical Decision Functions, Prague: Academic, 1973, 657674.［7］ Nagaev, S. V., Large deviations of sums of independent random variables, Ann. Prob., 1979, 7: 745.［8］ Embrechts, P., Klüppelberg, C., Mikosch, T., Modelling Extremal Events for Insurance and Finance, Berlin-Heidelberg: Springer-Verlag, 1997.［9］ Cline, D. B. H., Hsing, T., Large deviation probabilities for sums and maxima of random variables with heavy or subexponential tails, Preprint, Texas A&M University, 1991.［10］ Klüppelberg, C., Mikosch, T., Large deviations of heavy-tailed random sums with applications to insurance and finance, J. Appl. Prob., 1997, 34: 293.
Lasheen, Wael; Walsh, Declan; Mahmoud, Fade; Sarhill, Nabeel; Rivera, Nilo; Davis, Mellar; Lagman, Ruth; Legrand, Susan
2010-01-01
Morphine (M) is the opioid analgesic of choice for severe cancer pain. The IV to PO M equipotent switch ratio (CR) is controversial. We designed this prospective observational cohort to confirm the efficacy and safety of M IV to PO CR of 1:3. Consecutive cancer patients admitted to an inpatient palliative medicine unit were screened for inclusion. Pain was managed by palliative medicine specialists. They were blinded to the patient data collected, and the calculated CR. The switch was considered successful if the following criteria were met: (1) Pain adequately controlled: pain rated as none or mild (2) Number of RD less than 4 (for non incident pain) per 24 hours (3) No limiting side effects. We used Day 3 ATC M dose for CR calculations. The major outcome measures were the IV : PO CR ratio, morphine doses (mg/day), pain severity, number of PRN doses, and day 1 and day 3side effects. Descriptive statistics were used to report mean, median, standard deviation and range of different variables. Two hundred and fifty six consecutive admissions were screened, and 106 were eligible for the study. Sixty two underwent a successful M route switch and were included in this analysis. A ratio of 1:3 was safely implemented over a wide M dose range. About 80% were successfully switched with a calculated CR of 1:3. 20% required an oral M dose adjustment after route switch either to better pain control or reduce side effects with a resultant higher (e.g. 1:4) or lower (e.g. 1:2) calculated potency ratios respectively. A potency ratio of 1:3 was safe as evaluated by common M side-effects, the dose also easy to calculate. The 1: 3 M IV to PO relative milligram potency ratio appears correct and practical for most patients over a wide M dose range.
A large deviations approach to limit theory for heavy-tailed time series
Mikosch, Thomas Valentin; Wintenberger, Olivier
2016-01-01
In this paper we propagate a large deviations approach for proving limit theory for (generally) multivariate time series with heavy tails. We make this notion precise by introducing regularly varying time series. We provide general large deviation results for functionals acting on a sample path...... and vanishing in some neighborhood of the origin. We study a variety of such functionals, including large deviations of random walks, their suprema, the ruin functional, and further derive weak limit theory for maxima, point processes, cluster functionals and the tail empirical process. One of the main results...
Method for solving fully fuzzy linear programming problems using deviation degree measure
Haifang Cheng; Weilai Huang; Jianhu Cai
2013-01-01
A new ful y fuzzy linear programming (FFLP) prob-lem with fuzzy equality constraints is discussed. Using deviation degree measures, the FFLP problem is transformed into a crispδ-parametric linear programming (LP) problem. Giving the value of deviation degree in each constraint, the δ-fuzzy optimal so-lution of the FFLP problem can be obtained by solving this LP problem. An algorithm is also proposed to find a balance-fuzzy optimal solution between two goals in conflict: to improve the va-lues of the objective function and to decrease the values of the deviation degrees. A numerical example is solved to il ustrate the proposed method.
Non-equilibrium steady states: fluctuations and large deviations of the density and of the current
Derrida, Bernard
2007-07-01
These lecture notes give a short review of methods such as the matrix ansatz, the additivity principle or the macroscopic fluctuation theory, developed recently in the theory of non-equilibrium phenomena. They show how these methods allow us to calculate the fluctuations and large deviations of the density and the current in non-equilibrium steady states of systems like exclusion processes. The properties of these fluctuations and large deviation functions in non-equilibrium steady states (for example, non-Gaussian fluctuations of density or non-convexity of the large deviation function which generalizes the notion of free energy) are compared with those of systems at equilibrium.
Saito, Takuya
2017-09-01
We discuss a deviation of the fluctuation-dissipation relation (FDR) in a driven superdiffusive system as exemplified by polymer stretching. The superdiffusion is found by monitoring momentum transfer to a tracer, which is a conjugate observable with the position. Molecular-dynamics simulation demonstrates that the FDR deviates during the nonequilibrium transient process. We then propose nonequilibrium mode analysis for superdiffusion, which is a counterpart to that for driven subdiffusion. The mode analysis yields results that are in qualitative agreement with the simulation results, suggesting that the fluctuations of the stiffness in the system from initial equilibrium to stretching account for the FDR deviation.
Yue Bao WANG; Kai Yong WANG; Dong Ya CHENG
2006-01-01
In this paper, we obtain results on precise large deviations for non-random and random sums of negatively associated nonnegative random variables with common dominatedly varying tail distribution function. We discover that, under certain conditions, three precise large-deviation probabilities with different centering numbers are equivalent to each other. Furthermore, we investigate precise large deviations for sums of negatively associated nonnegative random variables with certain negatively dependent occurrences. The obtained results extend and improve the corresponding results of Ng, Tang, Yan and Yang (J. Appl. Prob., 41, 93-107, 2004).
Large deviation functions in a system of diffusing particles with creation and annihilation.
Popkov, V; Schütz, G M
2011-08-01
Large deviation functions for an exactly solvable lattice gas model of diffusing particles on a ring, subject to pair annihilation and creation, are obtained analytically using exact free-fermion techniques. Our findings for the large deviation function for the current are compared to recent results of Appert-Rolland et al. [Phys. Rev. E 78, 021122 (2008)] for diffusive systems with conserved particle number. Unlike conservative dynamics, our nonconservative model has no universal finite-size corrections for the cumulants. However, the leading Gaussian part has the same variance as in the conservative case. We also elucidate some properties of the large deviation functions associated with particle creation and annihilation.
Narikawa, Tatsuya
2016-01-01
We discuss the potential of the advanced ground-based gravitational-wave detectors, such as LIGO, Virgo, and KAGRA, to detect generic deviations of gravitational waveforms from the prediction of General Relativity. We use the parameterized post-Einsteinian formalism to characterize the deviations, and assess how much magnitude of the deviations are detectable by using an approximate decision scheme based on Bayesian statistics. We find that there exist detectable regions of the parameterized post-Einsteinian parameters by using a single gravitational wave event. The regions are not excluded by currently existing binary pulsar observations for the parameterized post-Einsteinian parameters at higher post-Newtonian order.
Loewe, Axel; Schulze, Walther H W; Jiang, Yuan; Wilhelms, Mathias; Luik, Armin; Dössel, Olaf; Seemann, Gunnar
2015-01-01
In case of chest pain, immediate diagnosis of myocardial ischemia is required to respond with an appropriate treatment. The diagnostic capability of the electrocardiogram (ECG), however, is strongly limited for ischemic events that do not lead to ST elevation. This computational study investigates the potential of different electrode setups in detecting early ischemia at 10 minutes after onset: standard 3-channel and 12-lead ECG as well as body surface potential maps (BSPMs). Further, it was assessed if an additional ECG electrode with optimized position or the right-sided Wilson leads can improve sensitivity of the standard 12-lead ECG. To this end, a simulation study was performed for 765 different locations and sizes of ischemia in the left ventricle. Improvements by adding a single, subject specifically optimized electrode were similar to those of the BSPM: 2-11% increased detection rate depending on the desired specificity. Adding right-sided Wilson leads had negligible effect. Absence of ST deviation could not be related to specific locations of the ischemic region or its transmurality. As alternative to the ST time integral as a feature of ST deviation, the K point deviation was introduced: the baseline deviation at the minimum of the ST-segment envelope signal, which increased 12-lead detection rate by 7% for a reasonable threshold.
Axel Loewe
2015-01-01
Full Text Available In case of chest pain, immediate diagnosis of myocardial ischemia is required to respond with an appropriate treatment. The diagnostic capability of the electrocardiogram (ECG, however, is strongly limited for ischemic events that do not lead to ST elevation. This computational study investigates the potential of different electrode setups in detecting early ischemia at 10 minutes after onset: standard 3-channel and 12-lead ECG as well as body surface potential maps (BSPMs. Further, it was assessed if an additional ECG electrode with optimized position or the right-sided Wilson leads can improve sensitivity of the standard 12-lead ECG. To this end, a simulation study was performed for 765 different locations and sizes of ischemia in the left ventricle. Improvements by adding a single, subject specifically optimized electrode were similar to those of the BSPM: 2–11% increased detection rate depending on the desired specificity. Adding right-sided Wilson leads had negligible effect. Absence of ST deviation could not be related to specific locations of the ischemic region or its transmurality. As alternative to the ST time integral as a feature of ST deviation, the K point deviation was introduced: the baseline deviation at the minimum of the ST-segment envelope signal, which increased 12-lead detection rate by 7% for a reasonable threshold.
Ascaso Carlos
2010-04-01
Full Text Available Abstract Background In an agreement assay, it is of interest to evaluate the degree of agreement between the different methods (devices, instruments or observers used to measure the same characteristic. We propose in this study a technical simplification for inference about the total deviation index (TDI estimate to assess agreement between two devices of normally-distributed measurements and describe its utility to evaluate inter- and intra-rater agreement if more than one reading per subject is available for each device. Methods We propose to estimate the TDI by constructing a probability interval of the difference in paired measurements between devices, and thereafter, we derive a tolerance interval (TI procedure as a natural way to make inferences about probability limit estimates. We also describe how the proposed method can be used to compute bounds of the coverage probability. Results The approach is illustrated in a real case example where the agreement between two instruments, a handle mercury sphygmomanometer device and an OMRON 711 automatic device, is assessed in a sample of 384 subjects where measures of systolic blood pressure were taken twice by each device. A simulation study procedure is implemented to evaluate and compare the accuracy of the approach to two already established methods, showing that the TI approximation produces accurate empirical confidence levels which are reasonably close to the nominal confidence level. Conclusions The method proposed is straightforward since the TDI estimate is derived directly from a probability interval of a normally-distributed variable in its original scale, without further transformations. Thereafter, a natural way of making inferences about this estimate is to derive the appropriate TI. Constructions of TI based on normal populations are implemented in most standard statistical packages, thus making it simpler for any practitioner to implement our proposal to assess agreement.
Higgs Branching Ratio Study in CEPC
HU; Shou-yang; LIANG; Hao; ZHOU; Jing; LI; Xiao-mei; LI; Xing-long; ZHOU; Shu-hua
2015-01-01
Higgs branching ratio(BR)measurement is one of the important issue of the Circular Electron Positron Collider(CEPC)project,which is strongly related to the coupling strength with particles and reveal their mass generation mechanism.The Large Hadron Collider(LHC)has discovered the Higgs boson in 2012,CEPC can confirm whether that is the standard model(SM)
Simulation of heat waves in climate models using large deviation algorithms
Ragone, Francesco; Bouchet, Freddy; Wouters, Jeroen
2016-04-01
One of the goals of climate science is to characterize the statistics of extreme, potentially dangerous events (e.g. exceptionally intense precipitations, wind gusts, heat waves) in the present and future climate. The study of extremes is however hindered by both a lack of past observational data for events with a return time larger than decades or centuries, and by the large computational cost required to perform a proper sampling of extreme statistics with state of the art climate models. The study of the dynamics leading to extreme events is especially difficult as it requires hundreds or thousands of realizations of the dynamical paths leading to similar extremes. We will discuss here a new numerical algorithm, based on large deviation theory, that allows to efficiently sample very rare events in complex climate models. A large ensemble of realizations are run in parallel, and selection and cloning procedures are applied in order to oversample the trajectories leading to the extremes of interest. The statistics and characteristic dynamics of the extremes can then be computed on a much larger sample of events. This kind of importance sampling method belongs to a class of genetic algorithms that have been successfully applied in other scientific fields (statistical mechanics, complex biomolecular dynamics), allowing to decrease by orders of magnitude the numerical cost required to sample extremes with respect to standard direct numerical sampling. We study the applicability of this method to the computation of the statistics of European surface temperatures with the Planet Simulator (Plasim), an intermediate complexity general circulation model of the atmosphere. We demonstrate the efficiency of the method by comparing its performances against standard approaches. Dynamical paths leading to heat waves are studied, enlightening the relation of Plasim heat waves with blocking events, and the dynamics leading to these events. We then discuss the feasibility of this
Testing the Standard Model with the Primordial Inflation Explorer
Kogut, Alan J.
2011-01-01
The Primordial Inflation Explorer is an Explorer-class mission to measure the gravity-wave signature of primordial inflation through its distinctive imprint on the linear polarization of the cosmic microwave background. PIXIE uses an innovative optical design to achieve background-limited sensitivity in 400 spectral channels spanning 2.5 decades in frequency from 30 GHz to 6 THz (1 cm to 50 micron wavelength). The principal science goal is the detection and characterization of linear polarization from an inflationary epoch in the early universe, with tensor-to-scalar ratio r < 10A{-3) at 5 standard deviations. The rich PIXIE data set will also constrain physical processes ranging from Big Bang cosmology to the nature of the first stars to physical conditions within the interstellar medium of the Galaxy. I describe the PIXIE instrument and mission architecture needed to detect the inflationary signature using only 4 semiconductor bolometers.
Zafar, Tayyaba
2013-01-01
Among the key parameters defining the ISM of galaxies is the fraction of the metals that are locked up in dust: the metals-to-dust ratio. This ratio bears not only on the ISM and its evolution, but particularly on the origin of cosmic dust. We combine extinction and abundance data from GRB afterglows, from QSO absorbers, as well as from galaxy-lensed QSOs, to determine the metals-to-dust ratios for lines-of-sight through a wide diversity of galaxies from blue, dwarf starbursts to massive ellipticals, across a vast range in redshift z=0.1-6.3, and nearly three orders of magnitude in column density and metal abundance. We thus determine the metals-to-dust ratio in a unique way, providing direct determinations of in situ gas and dust columns without recourse to assumptions with large uncertainties. We find that the metals-to-dust ratios in these systems are surprisingly close to the value for the local group (10^{21.3} cm-2 A_V mag-1), with a mean value of 10^{21.2} cm-2 A_V mag-1 and a standard deviation of 0.3...
Reddy Sreenivasulu
2016-05-01
Full Text Available This paper presents the influence of cutting parameters like cutting speed, feed rate, drill diameter, point angle and clearance angle on the surface roughness and circularity deviation of Alluminium alloys during drilling on CNC vertical machining center. A plan of experiments based on Taguchi method has been used to acquire the data. An orthogonal array, signal to noise (S/N ratio and analysis of variance (ANOVA are employed to investigate machining characteristics of Alluminium alloys using HSS twist drill bits of variable tool geometry and maintain constant helix angle of 45 degrees. Confirmation tests have been carried out to predict the optimal setting of process parameters to validate the proposed approach and obtained the values of 3.7451µm, 0.1076mm for surface roughness and circularity deviation respectively. Finally, the output results of taguchi method fed as input to the AHP and TOPSIS. the results generated in both AHP and TOPSIS suggests the suitable alternative of aluminium alloy, which results in better surface roughness and less error in circularity.
Hemingway’s Internal Deviation from His Primary Norm in The Old Man and the Sea
Trisnowati Tanto
2009-01-01
Full Text Available Ernest Hemingway is well known for the use of short and simple sentences when writing his novels since he aims at ‘[getting] the most out of the least’. This sentence-simplicity style is Hemingway’s primary norm. The Old Man and the Sea is the perfect example of this. However, in this novel, he sometimes uses long, complex sentences to describe certain points, and this sentence-complexity style can be said to be Hemingway’s secondary norm. In this case, there is a deviation within Hemingway’s own style of writing – an internal deviation. The deviation is obviously done on purpose as a kind of distraction so as to make the readers aware of the special and important ‘message’ that Hemingway wants to convey. In this novel, the deviation is used to build the elements of suspense and foreshadowing in much detail.
THE INFLUENCE OF TECHNICAL DEVIATIONS OVER EFFORTS FROM A 4R SPHERICAL QUADRILATERAL MECHANISM
Nicolae PANDREA
2013-05-01
Full Text Available In the present paper is mechanically defined the notion of technical deviation (geometrical through a matrix of pluckerian coordinates and those influence over the efforts from the 4R spherical quadrilateral mechanism elements.
Large Deviations for Stochastic Partial Differential Equations Driven by a Poisson Random Measure
Budhiraja, Amarjit; Dupuis, Paul
2012-01-01
Stochastic partial differential equations driven by Poisson random measures (PRM) have been proposed as models for many different physical systems, where they are viewed as a refinement of a corresponding noiseless partial differential equations (PDE). A systematic framework for the study of probabilities of deviations of the stochastic PDE from the deterministic PDE is through the theory of large deviations. The goal of this work is to develop the large deviation theory for small Poisson noise perturbations of a general class of deterministic infinite dimensional models. Although the analogous questions for finite dimensional systems have been well studied, there are currently no general results in the infinite dimensional setting. This is in part due to the fact that in this setting solutions may have little spatial regularity, and thus classical approximation methods for large deviation analysis become intractable. The approach taken here, which is based on a variational representation for nonnegative func...