WorldWideScience

Sample records for rapidly increasing economic

  1. Economic analyses of rapid population growth.

    Science.gov (United States)

    Birdsall, N

    1989-01-01

    "Discussion of the macroeconomic consequences of rapid population growth is organized into three schools: pessimists, optimists, and the recent revisionists. For the revisionists, differing views are presented about the pervasiveness and relevance of market failures, such as the negative externalities of childbearing, and about the ability of families and institutions to adjust rapidly to changes brought on by rapid population growth. A welfare economics approach is used to review the merits of various public policies to reduce fertility, including public financing of family planning services and taxes and incentives associated with childbearing." The focus is on developing countries. excerpt

  2. Africa: rapid population increase retards development.

    Science.gov (United States)

    1993-10-01

    The Organization of African Unity (OAU), the African Development Bank (ADB) and the UN Economic Commission for Africa (ECA) have criticized African governments for not taking the problem of unchecked population growth seriously enough. "Until recently most African governments did not view rapid population growth as a matter for concern," said the OAU assistant secretary-general for political affairs, Machivenyika Mapuranga, at a seminar on 'population and development'. The OAU estimates that an annual average population increase of 3.1% far outstrips Africa's economic growth, which in 1992 was less than 1%. Mapuranga acknowledged that cutting the population increase is an uphill struggle, especially among rural communities. African agriculture is largely labor intensive, sustained by smallholders, which encourages farmers to have more children. Like other wage earners, African farmers look to support from their family when they grow old and, for that reason, the number of children also counts. But with agricultural production growing at an average annual rate of 2.5%, self-sufficiency in food remains an elusive goal. Cities in sub-Saharan Africa are growing much faster than the overall rate of population increase of 3.1% per year. Between 1980 and 1988 the region's urban population increased at the rate of 6.9% a year. Urban areas now account for nearly 30% of the sub-Saharan Africa population, currently put at 680 million. By 2025, approximately 700 million people are expected to live in urban areas. Despite migration to towns, the rural population is expected to rise more than 68%, reaching over 590 million. full text

  3. Economic inequality increases risk taking.

    Science.gov (United States)

    Payne, B Keith; Brown-Iannuzzi, Jazmin L; Hannay, Jason W

    2017-05-02

    Rising income inequality is a global trend. Increased income inequality has been associated with higher rates of crime, greater consumer debt, and poorer health outcomes. The mechanisms linking inequality to poor outcomes among individuals are poorly understood. This research tested a behavioral account linking inequality to individual decision making. In three experiments ( n = 811), we found that higher inequality in the outcomes of an economic game led participants to take greater risks to try to achieve higher outcomes. This effect of unequal distributions on risk taking was driven by upward social comparisons. Next, we estimated economic risk taking in daily life using large-scale data from internet searches. Risk taking was higher in states with greater income inequality, an effect driven by inequality at the upper end of the income distribution. Results suggest that inequality may promote poor outcomes, in part, by increasing risky behavior.

  4. [Electrical acupoint stimulation increases athletes' rapid strength].

    Science.gov (United States)

    Yang, Hua-yuan; Liu, Tang-yi; Kuai, Le; Gao, Ming

    2006-05-01

    To search for a stimulation method for increasing athletes' performance. One hundred and fifty athletes were randomly divided into a trial group and a control group, 75 athletes in each group. Acupoints were stimulated with audio frequency pulse modulated wave and multi-blind method were used to investigate effects of the electric stimulation of acupoints on 30-meter running, standing long jumping and Cybex isokinetic testing index. The acupoint electric stimulation method could significantly increase athlete's performance (P < 0.05), and the biomechanical indexes, maximal peak moment of force (P < 0.05), force moment accelerating energy (P < 0.05) and average power (P < 0.05). Electrical acupoint stimulation can enhance athlete's rapid strength.

  5. Economic Growth of a Rapidly Developing Economy: Theoretical Formulation

    Directory of Open Access Journals (Sweden)

    Oleg Sergeyevich Sukharev

    2016-06-01

    Full Text Available The subject matter of the article is the description of economic growth. Modern economy is characterized by a high rate of changes. These changes are the limiting parameters of modern development, which requires a modification of the basic models of growth, the substantiation of the expediency and necessity of a rapid development strategy. In a simple mathematical form, the statement of the problem of economic growth in the “green economy” is examined, in which the costs of environmental measures are not considered a priori as hampering economic development (as it is common for a number of modern neoclassical and neo-Keynesian growth models. The methodological basis of the article are the econometric approach and modelling method. The article has a theoretical character. The main hypothesis supposes that the rapid development strategy cannot make an adequate development strategy under certain conditions, but may be acceptable in other its specific conditions. In this sense, the important growth conditions are the availability of resources, the effectiveness of institutions and the current economic structure, the technological effectiveness of economy, as well as the conditions of technological development (“green economy” and the path of such development. In the article, on the theoretical level of analysis, the substantiation of the adequacy of the rapid development strategy for an economic system is given, whose goal is to achieve the standard of living of the countryleader. Based on the assumptions introduced, the period for which the rapid development strategy might be implemented and the economic lag of the country might be reduced from the country-leader is determined. The conditions that ensure the impact of innovations on the rate of economic development are summarized. The introduced range of dependencies and relations can be useful for the elaboration of the theory of innovation development and for the formation of a new

  6. Rapid estimation of the economic consequences of global earthquakes

    Science.gov (United States)

    Jaiswal, Kishor; Wald, David J.

    2011-01-01

    The U.S. Geological Survey's (USGS) Prompt Assessment of Global Earthquakes for Response (PAGER) system, operational since mid 2007, rapidly estimates the most affected locations and the population exposure at different levels of shaking intensities. The PAGER system has significantly improved the way aid agencies determine the scale of response needed in the aftermath of an earthquake. For example, the PAGER exposure estimates provided reasonably accurate assessments of the scale and spatial extent of the damage and losses following the 2008 Wenchuan earthquake (Mw 7.9) in China, the 2009 L'Aquila earthquake (Mw 6.3) in Italy, the 2010 Haiti earthquake (Mw 7.0), and the 2010 Chile earthquake (Mw 8.8). Nevertheless, some engineering and seismological expertise is often required to digest PAGER's exposure estimate and turn it into estimated fatalities and economic losses. This has been the focus of PAGER's most recent development. With the new loss-estimation component of the PAGER system it is now possible to produce rapid estimation of expected fatalities for global earthquakes (Jaiswal and others, 2009). While an estimate of earthquake fatalities is a fundamental indicator of potential human consequences in developing countries (for example, Iran, Pakistan, Haiti, Peru, and many others), economic consequences often drive the responses in much of the developed world (for example, New Zealand, the United States, and Chile), where the improved structural behavior of seismically resistant buildings significantly reduces earthquake casualties. Rapid availability of estimates of both fatalities and economic losses can be a valuable resource. The total time needed to determine the actual scope of an earthquake disaster and to respond effectively varies from country to country. It can take days or sometimes weeks before the damage and consequences of a disaster can be understood both socially and economically. The objective of the U.S. Geological Survey's PAGER system is

  7. Strong economic growth driving increased electricity consumption

    International Nuclear Information System (INIS)

    Tiusanen, P.

    2000-01-01

    The Finnish economy is growing faster today than anyone dared hope only a few years ago. Growth estimates for 2000 have already had to be raised. This strong level of economic growth has been reflected in electricity consumption, which has continued to increase, despite the exceptionally warm winter. A major part of this increased electricity usage has so far been met through imports. The continued growth in electricity imports has largely been a result of the fact that the good water level situation in Sweden and Norway, together with the mild winter, has kept electricity prices exceptionally low on the Nordic electricity exchange. The short period of low temperatures seen at the end of January showed, however, that this type of temperature fluctuation, combined with the restrictions that exist in regard to transfer capacity, can serve to push Nordic exchange electricity prices to record levels. This increase in price also highlights the fact that we are approaching a situation in which capacity will be insufficient to meet demand. A truly tough winter has not been seen since the Nordic region's electricity markets were deregulated. The lesson that needs to be learnt is that Finland needs sufficient capacity of her own to meet demand even during particularly cold winters. Finland used 77.9 billion kWh of electricity last year, up 1.6% or 1.3 billion kWh on 1998. This growth was relatively evenly distributed among different user groups. This year, electricity consumption is forecast to grow by 2-3%

  8. eRME - Rapid Maxillary Expansion in the economic way

    Directory of Open Access Journals (Sweden)

    Sonali Mahadevia

    2011-01-01

    Full Text Available Aim and Objectives: Rapid Maxillary Expansion constitutes a routine clinical procedure in orthodontics, involving separation of mid-palatine suture which is usually done with help of the Hyrax screw. However, because of its high cost, the use has been limited, especially in institutions. So, the purpose of this study was to construct an economical device which can expand the maxillary arch in growing patients. Materials and Methods: Six patients having constricted maxilla and posterior skeletal crossbite were randomly selected from the Department of Orthodontics. A unique, easy and simple alternative device for expanding the maxillary arch called economic Rapid Maxillary Expander (eRME has been fabricated at about one-tenth the cost of the conventional Hyrax. Pre- and post-treatment effects were statistically tested by using paired t-test at 0.05 level of significance. Results and Conclusion: The study results showed an average expansion in canine, premolar and molar regions of 4.4 mm, 6.8 mm and 9.4 mm, respectively, having significant difference pre-and post-treatment. Thus, it shows that maxillary expansion is efficiently possible with the application of this newly constructed device named eRME. This appliance also acts as a fixed retainer to avoid relapse, hence negating the need for a separate retainer.

  9. Are Global Economic Losses from Natural Hazards Increasing?

    Science.gov (United States)

    McMullan, Caroline; Simic, Milan; Tosco, Antonello; Latchman, Shane

    2016-04-01

    Global society has long been influenced by natural hazards, but it has been widely noted that the economic cost of natural hazards has been rising rapidly over recent decades. This upward trend highlights the increasing exposure of the global economy to natural hazards and the need for society to understand the driving factors to help improve the resilience of communities. However disaster risk is driven by a plethora of factors, including population, wealth, land-use, and demographics. Consider also the natural variability in the frequency and severity of events, climate change, and implementation of resilience policies, and it becomes clear that disaster-risk management is a challenging field. To investigate the apparent upward trend in reported annual economic losses from natural disasters, socioeconomic factors known to influence the magnitude of losses must first be accounted for. Adjustment for these factors, known as loss normalisation, aims to estimate the losses sustained if historical events were to impact present day society. We have undertaken a detailed assessment of global economic losses from natural disasters for the period 1995 through 2013. Although the studied time-period is relatively short, expanding the investigated period would not necessarily produce more reliable insights owing to the inherent difficulty in obtaining accurate economic loss estimates for earlier periods and the challenge of finding consistent and reliable sources of socioeconomic data for the normalisation process. The results of the study, presented at a global and regional level, appear to suggest that the main driver of perceived increase in economic losses over the last ~20 years was the development of nations' economies (i.e. increase in population and wealth/GDP) and not in the natural hazards themselves. As populations all over the world migrate into areas of higher natural hazards regions (e.g. coastal areas or floodplain zones) and global wealth continues to

  10. BENEFITS, COSTS AND LIMITS OF ECONOMIC INCREASE

    Directory of Open Access Journals (Sweden)

    VĂDUVA CECILIA ELENA

    2014-08-01

    Full Text Available The macroeconomic situation of a nation cannot be characterized just by the equilibrium conditions of its economy, but especially by the growth level and rate of the gross domestic product or the national, total income and per inhabitant. These are at the base to ensure the resources to raise the life standard of people, and for the overall progress of the country, for its honorable placement or framing in the national economy. The oscillations of the economic activities and the long term trend interweaved along centuries. Looked in a millenary retrospective by “L'Histoire” known magazine, they appear like: “while the brutal, short-term crises are well sighted, and the tri-decennial cycles have been defined by the Russian economist Kondratieff and are admitted, the long term movements are less known, those trends which make the succession of “The beautiful of the XIV century”, “The gloomy of the XVII century” and the XIX century, considered “grey”, the extraordinary of the XX century, the economics and economic historians are far from agreeing on the reality of these long movements, and if they admit them, they separate on their profound causes.”

  11. Rapid increases in tropospheric ozone production and export from China

    NARCIS (Netherlands)

    Verstraeten, W.W.; Neu, J.L.; Williams, J.E.; Bowman, K.W.; Worden, J.R.; Boersma, K.F.

    2015-01-01

    Rapid population growth and industrialization have driven substantial increases in Asian ozone precursor emissions over the past decade1, with highly uncertain impacts on regional and global tropospheric ozone levels. According to ozonesonde measurements2, 3, tropospheric ozone concentrations at two

  12. Mechanisms Underlying Early Rapid Increases in Creatinine in Paraquat Poisoning

    Science.gov (United States)

    Mohamed, Fahim; Endre, Zoltan; Jayamanne, Shaluka; Pianta, Timothy; Peake, Philip; Palangasinghe, Chathura; Chathuranga, Umesh; Jayasekera, Kithsiri; Wunnapuk, Klintean; Shihana, Fathima; Shahmy, Seyed; Buckley, Nicholas

    2015-01-01

    Background Acute kidney injury (AKI) is common after severe paraquat poisoning and usually heralds a fatal outcome. The rapid large increases in serum creatinine (Cr) exceed that which can be explained by creatinine kinetics based on loss of glomerular filtration rate (GFR). Methods and Findings This prospective multi-centre study compared the kinetics of two surrogate markers of GFR, serum creatinine and serum cystatin C (CysC), following paraquat poisoning to understand and assess renal functional loss after paraquat poisoning. Sixty-six acute paraquat poisoning patients admitted to medical units of five hospitals were included. Relative changes in creatinine and CysC were monitored in serial blood and urine samples, and influences of non-renal factors were also studied. Results Forty-eight of 66 patients developed AKI (AKIN criteria), with 37 (56%) developing moderate to severe AKI (AKIN stage 2 or 3). The 37 patients showed rapid increases in creatinine of >100% within 24 hours, >200% within 48 hours and >300% by 72 hours and 17 of the 37 died. CysC concentration increased by 50% at 24 hours in the same 37 patients and then remained constant. The creatinine/CysC ratio increased 8 fold over 72 hours. There was a modest fall in urinary creatinine and serum/urine creatinine ratios and a moderate increase in urinary paraquat during first three days. Conclusion Loss of renal function contributes modestly to the large increases in creatinine following paraquat poisoning. The rapid rise in serum creatinine most probably represents increased production of creatine and creatinine to meet the energy demand following severe oxidative stress. Minor contributions include increased cyclisation of creatine to creatinine because of acidosis and competitive or non-competitive inhibition of creatinine secretion. Creatinine is not a good marker of renal functional loss after paraquat poisoning and renal injury should be evaluated using more specific biomarkers of renal injury

  13. Health impacts of rapid economic changes in Thailand.

    Science.gov (United States)

    Tangcharoensathien, V; Harnvoravongchai, P; Pitayarangsarit, S; Kasemsup, V

    2000-09-01

    The economic crisis in Thailand in July 1997 had major social implications for unemployment, under employment, household income contraction, changing expenditure patterns, and child abandonment. The crisis increased poverty incidence by 1 million, of whom 54% were the ultra-poor. This paper explores and explains the short-term health impact of the crisis, using existing data and some special surveys and interviews for 2 years during 1998-99. The health impacts of the crisis are mixed, some being negative and some being positive. Household health expenditure reduced by 24% in real terms; among the poorer households, institutional care was replaced by self-medication. The pre-crisis rising trend in expenditure on alcohol and tobacco consumption was reversed. Immunization spending and coverage were sustained at a very high level after the crisis, but reports of increases in diphtheria and pertussis indicate declining programme quality. An increase in malaria, despite budget increases, had many causes but was mainly due to reduced programme effectiveness. STD incidence continued the pre-crisis downward trend. Rates of HIV risky sexual behaviour were higher among conscripts than other male workers, but in both groups there was lower condom use with casual partners. HIV serosurveillance showed a continuation of the pre-crisis downward trend among commercial sex workers (CSW, both brothel and non-brothel based), pregnant women and donated blood; this trend was slightly reversed among male STD patients and more among intravenous drug users. Condom coverage among brothel based CSW continued to increase to 97.5%, despite a 72% budget cut in free condom distribution. Poverty and lack of insurance coverage are two major determinants of absence of or inadequate antenatal care, and low birthweight. The Low Income Scheme could not adequately cover the poor but the voluntary Health Card Scheme played a health safety net role for maternal and child health. Low birthweight and

  14. The impact of rapid economic growth and globalization on zinc nutrition in South Korea.

    Science.gov (United States)

    Kwun, In-Sook; Do, Mi-Sook; Chung, Hae-Rang; Kim, Yang Ha; Beattie, John H

    2009-08-01

    Zn deficiency may be widespread in Asian countries such as South Korea. However, dietary habits have changed in response to rapid economic growth and globalization. Zn nutrition in South Koreans has therefore been assessed during a period (1969-1998) of unprecedented economic growth. Cross-sectional food consumption data from the Korean National Nutrition Survey Reports (KNNSR) of South Korea at four separate time points (1969, 1978, 1988 and 1998) were used to calculate Zn, Ca and phytate intakes using various food composition tables, databases and literature values. Nutrient values in local foods were cited from their analysed values. Average Zn intake was 5.8, 4.8 and 5.3 mg/d for 1969, 1978 and 1988 respectively, increasing to 7.3 mg/d in 1998 (73 % of the Korean Dietary Reference Intake). The phytate:Zn molar ratio decreased from 21 to 8 during the study period. Dietary Zn depletion due to marked decreases in cereal consumption, particularly barley which has a low Zn bioavailability, was counterbalanced by marked increases in the consumption of meat and fish, which are also Zn-rich foods. Reduced phytate consumption coincident with increased Zn intake suggests that Zn bioavailability also improved, particularly by 1998. Although total Zn intake was not greatly affected over the initial period of economic growth in South Korea (1969-1988), Zn contributions from different food sources changed markedly and both Zn intake and potential bioavailability were improved by 1998. The study may have implications for Zn nutrition in other Asian countries currently experiencing rapid economic growth.

  15. Economic impacts of bus rapid transit in southeast Michigan.

    Science.gov (United States)

    2015-12-01

    In recent years, Bus Rapid Transit (BRT) has generated great interest across the United States. There are more than 20 BRT : systems in existence, and more are in the planning stage (including in Detroit). Within the next few years, BRT will be plann...

  16. Energy price increases and economic development in Malaysia.

    OpenAIRE

    Fong CO

    1984-01-01

    ILO pub-WEP pub. Working paper on the impact of higher energy costs (particularly petroleum price increases) on economic development in Malaysia, 1973 to 1983 - outlines trends in gross domestic product, balance of payments, trade and economic growth; considers household income and fuel expenditure of low income rural communitys; deals with choice of technology and employment in certain high power consumption industries; discusses energy policy implications. Graphs, maps, questionnaires, refe...

  17. Increased wood-fiber production: technology, economics, and ecology

    Science.gov (United States)

    William R. Bentley

    1973-01-01

    Forest tree improvement is a form of technological change, and it should be viewed as such. The economic objective of technological change is to increase productivity per dollar invested. This is accomplished through selection and breeding for increased growth rates or reduced losses to insects and disease. Programs which yield improved planting stock make forest...

  18. Socio-economic status by rapid appraisal is highly correlated with mortality risks in rural Africa

    NARCIS (Netherlands)

    van Bodegom, D.; May, L.; Kuningas, M.; Kaptijn, R.; Thomese, G.C.F.; Meij, H.J.; Amankwa, J.; Westendorp, R.G.J.

    2009-01-01

    Socio-economic status is an important determinant of health and survival in rural Africa and necessitates a practical and valid instrument to implement in health studies. Our objective was to investigate the validity of the rapid appraisal method to assess socio-economic status and its ability to

  19. Economic impact of reduced mortality due to increased cycling.

    Science.gov (United States)

    Rutter, Harry; Cavill, Nick; Racioppi, Francesca; Dinsdale, Hywell; Oja, Pekka; Kahlmeier, Sonja

    2013-01-01

    Increasing regular physical activity is a key public health goal. One strategy is to change the physical environment to encourage walking and cycling, requiring partnerships with the transport and urban planning sectors. Economic evaluation is an important factor in the decision to fund any new transport scheme, but techniques for assessing the economic value of the health benefits of cycling and walking have tended to be less sophisticated than the approaches used for assessing other benefits. This study aimed to produce a practical tool for estimating the economic impact of reduced mortality due to increased cycling. The tool was intended to be transparent, easy to use, reliable, and based on conservative assumptions and default values, which can be used in the absence of local data. It addressed the question: For a given volume of cycling within a defined population, what is the economic value of the health benefits? The authors used published estimates of relative risk of all-cause mortality among regular cyclists and applied these to levels of cycling defined by the user to produce an estimate of the number of deaths potentially averted because of regular cycling. The tool then calculates the economic value of the deaths averted using the "value of a statistical life." The outputs of the tool support decision making on cycle infrastructure or policies, or can be used as part of an integrated economic appraisal. The tool's unique contribution is that it takes a public health approach to a transport problem, addresses it in epidemiologic terms, and places the results back into the transport context. Examples of its use include its adoption by the English and Swedish departments of transport as the recommended methodologic approach for estimating the health impact of walking and cycling. Copyright © 2013 World Health Organization. Published by Elsevier Inc. All rights reserved.

  20. Skills Management: A Base for Increasing Economic Competitiveness in Romania

    Directory of Open Access Journals (Sweden)

    Viorica CHIŞU

    2012-06-01

    Full Text Available The study incorporates an analysis of the performance of higher education system (the Bologna Model from the perspective of evaluations made by companies. The main objective is to identify the competence areas required from fresh graduates for sustaining the contention of business enterprises and to analyse investments made by companies for developing talents within the framework of pressure generated by the economic crisis. The study take into consideration the partnership between the economic environment and higher education institutions as well as an anticipation of occupation trends for young graduates based on employee forecasts. Research results demonstrate the fact that the education system relies mainly on a transfer of knowledge and not on developing the competencies necessary for enhancing the employment chances of graduates or on their job performance. Only two out of ten employers are satisfied by the competencies demonstrated by graduates, the statistics being similar to the number of employers who collaborate with higher education institutions for providing adequate study programmes. From amongst the companies declaring that they provide continual development programmes, most invest in courses related to communication, team work and client orientation, although they are not satisfied with the graduates’ abilities in solving problems, making decisions or in leadership. A weak collaboration between companies and educational institutions generates a lack of rapid response from the educational system to the requirements of the market economy, amplifying the deficiency of competences, especially in fields with continual technological development or in those where new occupations are constantly appearing.

  1. Economic Effects of Increased Control Zone Sizes in Conflict Resolution

    Science.gov (United States)

    Datta, Koushik

    1998-01-01

    A methodology for estimating the economic effects of different control zone sizes used in conflict resolutions between aircraft is presented in this paper. The methodology is based on estimating the difference in flight times of aircraft with and without the control zone, and converting the difference into a direct operating cost. Using this methodology the effects of increased lateral and vertical control zone sizes are evaluated.

  2. Rapid determination of the hypoxanthine increase in ischemic exercise tests

    NARCIS (Netherlands)

    Bolhuis, P. A.; Zwart, R.; Bär, P. R.; de Visser, M.; van der Helm, H. J.

    1988-01-01

    After ischemic exercise tests, performed to detect glycogenoses or myoadenylate deaminase (EC 3.5.4.6) deficiency, the increases in serum lactate and ammonia usually are measured. Determination of hypoxanthine instead of ammonia can also be used to show myoadenylate deaminase deficiency, but HPLC of

  3. Applying lessons from behavioral economics to increase flu vaccination rates.

    Science.gov (United States)

    Chen, Frederick; Stevens, Ryan

    2017-12-01

    Seasonal influenza imposes an enormous burden on society every year, yet many people refuse to obtain flu shots due to misconceptions of the flu vaccine. We argue that recent research in psychology and behavioral economics may provide the answers to why people hold mistaken beliefs about flu shots, how we can correct these misconceptions, and what policy-makers can do to increase flu vaccination rates. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  4. Economic repercussions of OPEC's crude oil price increases

    Energy Technology Data Exchange (ETDEWEB)

    Merklein, H A

    1980-05-01

    Accusations that the Organization of Petroleum Exporting Countries (OPEC) created the world energy crisis and destroyed the economies of oil-importing nations are challenged by Dr. Merklein. He shows that the economic impact of OPEC price increases have only accelerated an already-developing energy shortage and only reflect the existing problems of inflation, unemployment, and declining currency exchange rates. The real problem is argued to be a US energy policy that is incapable of responding appropriately to what should be a manageable crude oil tax. When the arguments against OPEC policies are examined in an historical context, they are shown to be essentially neutral. 4 tables. (DCK)

  5. Rapid population increase in an introduced muskox population, West Greenland

    Directory of Open Access Journals (Sweden)

    Carsten Riis Olesen

    1993-10-01

    Full Text Available In 1962 and 1965, 27 (13 and 14 muskox yearlings were translocated from East Greenland (71°N to the Angujaartorfiup Nunaa range in West Greenland (67°N. Angujaartorfiup Nunaa is a 6600 km2 icefree, continental area where caribou are indigenous. The climate is strictly continental with a minimum of precipitation but with abundant vegetation. Aerial surveys in 1990 documented that the muskox population has increased to 2600 heads despite quota-based harvesting since 1988. The annual quota was 200, 300 and 400 for 1988, 1989 and 1990, respectively. Distribution of muskoxen shows a significant preference for low altitude habitats southeast of Kangerlussuaq Airport and around Arnangarnup Qoorua (Paradise valley. Annual population increment averages 30% and the calf crop is around 24% of the population. Yearling recruitment in the population reveals that calf mortality during winter is very limited. About half of the 1-year-old females are served and they eventually give birth to their first calf when they turn 2 years old. With half of the 2-year-old females reproducing, the calf/cow ration ranges between 0.9 and 1.0.

  6. ORGANIZATIONAL AND ECONOMIC ASPECTS OF INCREASING COMPETITIVENESS OF UKRAINIAN BANKS

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    Ivanova S.

    2018-01-01

    Full Text Available Introduction. Modern business conditions and comprehensive economic globalization put the banking institutions at the forefront of the task of achieving and maintaining a high level of competitiveness both on the domestic and on the external financial markets, as banks serve as the main intermediaries in the whole complex of relationships between different economic subjects. To achieve and maintain the competitiveness of banks it is important to create an effective management mechanism, which determines the relevance of the chosen topic. Purpose. The purpose of the work is to summarize the existing theoretical aspects concerning the competitiveness of banks and develop organizational and economic approaches to its enhancement and implementation in banking practice. Results. The article generalizes the notion of competitiveness as an economic category and defines the main approaches of scientists to its interpretation. The role and importance of foreign capital in the banking system and its impact on the competitiveness of banks are considered, and the share of foreign capital in the authorized capital of banks for the period of 2008-2017 is calculated. On the basis of the comparative analysis, the impact on the competitiveness of the largest banking institutions of Ukraine on the performance indicators, such as volumes of assets, liabilities of banks and capital adequacy, was investigated. The possibility of increasing the efficiency of the mechanism of ensuring competitiveness according to the process approach is outlined. By means of the Microsoft Office Visio software system, the Bank’s own Banking Business Management business process was built to ensure the bank’s viability and its structural analysis according to the IDEF0 standard of the SADT methodology. Conclusions. The relationship between the analysis of the bank’s position and the development of its development strategy is important for the understanding and effective management

  7. Increase Economic Valuation of Marine Ecotourism Spots In Small Islands

    Science.gov (United States)

    Rahakbauw, Siska D.; Teniwut, Wellem A.; Renjaan, Meiskyana R.; Hungan, Marselus

    2017-10-01

    Ecotourism is one of the fast-growing sectors especially in the developing country as a source of revenue. To get a sustainable development of ecotourism, it needs broad and comprehensive effort from central government and local government, perfect example in that regards in Indonesia is Bali and Lombok. For another area in Indonesia like Kei Islands which located in two administrative governments have a major problem to build a sustainable nature-based tourism because of the location of this area to the major cities in the country makes the travel cost is high. This situation makes the role of local community as the backbone of the growth and development of nature-based tourism is critical. By using structural equation modeling (SEM), we constructed a model to enhance local community perception on economic valuation of ecotourism spots in the area. Results showed that perceived quality as the mediation driven by the intensity of appearance on national television and the internet could increase community attachment to increase willingness to pay from the local community on ecotourism in Kei islands. Also, the result also indicated that WTP value for the local community on ecotourism in Kei Islands was 10.81 per trip, with average trip per month was 1 to 4 times.

  8. Think Again: Higher Elasticity of Substitution Increases Economic Resilience

    OpenAIRE

    P. Dumas; S. Hallegatte

    2009-01-01

    This paper shows that, counter-intuitively, a higher elasticity of substitution in model production function can lead to reduced economic resilience and larger vulnerability to shocks in production factor prices. This result is due to the fact that assuming a higher elasticity of substitution requires a recalibration of the production function parameters to keep the model initial state unchanged. This result has consequences for economic analysis, e.g., on the economic vulnerability to climat...

  9. On Rural Financial and Accounting Work under the Background of Rapid Agricultural Economic Development

    OpenAIRE

    Tang, Yaozheng

    2013-01-01

    Under the background of rapid agricultural economic development, rural financial and accounting work is of great significance. From rural accounting management system, rural accountant allocation and rural accounting training, this paper analyzes current situations of rural accounting work in China. In rural financial and accounting work, there are following problems. (1) Accounting behavior is not standard, and basic accounting work is to be further strengthened; (2) Internal control is not ...

  10. Two Essays on Increasing the Learning Effectiveness of Economics Education

    Science.gov (United States)

    McLean, William J.

    2010-01-01

    Scope and Method of Study: This study develops, implements, and evaluates a new economics teaching pedagogy based on the U.S. Army's systems approach to training model. Using the approach, tasks are identified that compose the task domain for the Principles of Microeconomics course. From the 130 identified tasks, 73 are used by Economics of…

  11. Increasing Impact of Economic Conditions upon Higher Education Enrollments.

    Science.gov (United States)

    Rusk, James J.; And Others

    1982-01-01

    To assess the impact of economic conditions on enrollment in higher education, researchers used time series analysis on national data for 1966-78 and on 1972-78 data from all eight regions of the country and the University of Arizona. The findings indicate enrollment has gone up during economic downturns. (Author/RW)

  12. INCREASING ECONOMIC WELFARE OF CHURCH CONGREGATION : A CONCEPT OF EMPOWERMENT

    Directory of Open Access Journals (Sweden)

    TONGAM SIHOL NABABAN

    2017-03-01

    Full Text Available In our community, many structural problems unresolved well, especially in social and economic life. Seeing this reality, the Church needs to have a sensitivity and a strong commitment to encourage cooperation of some parties to empower people, especially its congregation. Congregation of the Church, especially the poor need to be raised and empowered to pursue their own welfare through economic business. One manifestation of the Church's task is to empower the community-based and to revitalize its role more focused on optimizing the institution of community economy. For that, it is important to use the Model of Empowerment of Congregation-Based Community Economic in form of business partnership. The success of congregation economic empowerment lies in the motivation and orientation of the actors themselves, where the Church is expected to seriously fight. Keywords: Church, Congregation, Community-Based Economic, Business Partnership,  Empowerment.

  13. Approach to increasing techno-economic effects of ventilation in uranium mines

    International Nuclear Information System (INIS)

    Zhou Xinhuo

    1989-01-01

    The main factors affecting techno-economic effects of ventilation in uranium mines are discussed in this paper. Under the conditions of technical feasibility and economic rationality, the method of economic analysis for ventilation and radiation protection in uranium mines is proposed. The technically feasible and economically reasonable suggestions are presented for increasing the techno-economic effects of ventilation in uranium mines

  14. Analysis of Increasing Malwares and Cyber Crimes Using Economic Approach

    OpenAIRE

    Asgher, Umer; Dar, Fahad Moazzam; Hamza, Ali; Paracha, Abdul Moeed

    2014-01-01

    The economics of an internet crime has newly developed into a field of controlling black money. This economic approach not only provides estimated technique of analyzing internet crimes but also gives details to analyzers of system dependability and divergence. This paper will highlight on the subject of online crime, which has formed its industry since. It all started from amateur hackers who cracked websites and wrote malicious software in pursuit of fun or achieving limited objectives to p...

  15. Human Mobility Analysis for Extracting Local Interactions under Rapid Socio-Economic Transformation in Dawei, Myanmar

    Directory of Open Access Journals (Sweden)

    Satomi Kimijima

    2017-09-01

    Full Text Available Understanding human mobility patterns provides knowledge about impacts of a socio-economic transformation in a rapidly urbanizing environment. This study assesses a long-term mobility data which uses a face-to-face questionnaire and GPS logger-based method of data collection for extracting socio-economic impacts from the rapid transformation. Conversion of mobility related information such as travel distance, direction, and time from the questionnaire survey into spatiotemporal information was carried out by developing an algorithm. To illustrate the proposed approach, a case study in Dawei Special Economic Zone, Myanmar was conducted. The results show that the questionnaire-based mobility data can be associated with GPS-based mobility data and diverse mobility patterns are found for different social groups in the stage of urban formation. The results enabled an understanding of the human dynamics in interactions, which can be used for monitoring rural sustainability and its challenges in the future with the background of the accelerated project development in the area.

  16. Rapid and economical data acquisition in ultrafast frequency-resolved spectroscopy using choppers and a microcontroller.

    Science.gov (United States)

    Guo, Liang; Monahan, Daniele M; Fleming, Graham

    2016-08-08

    Spectrometers and cameras are used in ultrafast spectroscopy to achieve high resolution in both time and frequency domains. Frequency-resolved signals from the camera pixels cannot be processed by common lock-in amplifiers, which have only a limited number of input channels. Here we demonstrate a rapid and economical method that achieves the function of a lock-in amplifier using mechanical choppers and a programmable microcontroller. We demonstrate the method's effectiveness by performing a frequency-resolved pump-probe measurement on the dye Nile Blue in solution.

  17. Challenges of rapid economic growth in China: Reconciling sustainable energy use, environmental stewardship and social development

    International Nuclear Information System (INIS)

    Li Yong; Oberheitmann, Andreas

    2009-01-01

    China aims at quadrupling per-capita GDP by 2020 compared to the year 2000. Without any energy and environmental policy measures, this tremendous economic growth would be associated with a quadrupling of primary energy consumption up to 6.3 billion tons of standard coal equivalents (sce) and energy-related CO 2 -emissions of 13.9 billion tons Against this background, this paper is to set China's need to implement its sustainable development strategy into the quantitative context of the countries economic development and subsequent economic growth-related environmental problems. China is urgently searching for a way to ease the negative implications of economic growth and has committed itself to achieve a level of 3.0 billion ton sce primary energy consumption in 2020. As a consequence, the macro-economic energy intensity has to be reduced by 53% by 2020. A reduction of 53% by 2020 would lead to an energy intensity level 30% points below the year-2000 level of developed countries. As for natural resources, the expected economic growth will lead to an increase of crude oil net-imports up to 455 million ton sce in 2020 and 650 million ton sce in 2030. As for regional income distribution, economic growth helped to decrease existing inequities

  18. Insight into the Physical and Dynamical Processes that Control Rapid Increases in Total Flash Rate

    Science.gov (United States)

    Schultz, Christopher J.; Carey, Lawrence D.; Schultz, Elise V.; Blakeslee, Richard J.; Goodman, Steven J.

    2015-01-01

    Rapid increases in total lightning (also termed "lightning jumps") have been observed for many decades. Lightning jumps have been well correlated to severe and hazardous weather occurrence. The main focus of lightning jump work has been on the development of lightning algorithms to be used in real-time assessment of storm intensity. However, in these studies it is typically assumed that the updraft "increases" without direct measurements of the vertical motion, or specification of which updraft characteristic actually increases (e.g., average speed, maximum speed, or convective updraft volume). Therefore, an end-to-end physical and dynamical basis for coupling rapid increases in total flash rate to increases in updraft speed and volume must be understood in order to ultimately relate lightning occurrence to severe storm metrics. Herein, we use polarimetric, multi-Doppler, and lightning mapping array measurements to provide physical context as to why rapid increases in total lightning are closely tied to severe and hazardous weather.

  19. A rapid and economic in-house DNA purification method using glass syringe filters.

    Directory of Open Access Journals (Sweden)

    Yun-Cheol Kim

    Full Text Available BACKGROUND: Purity, yield, speed and cost are important considerations in plasmid purification, but it is difficult to achieve all of these at the same time. Currently, there are many protocols and kits for DNA purification, however none maximize all four considerations. METHODOLOGY/PRINCIPAL FINDINGS: We now describe a fast, efficient and economic in-house protocol for plasmid preparation using glass syringe filters. Plasmid yield and quality as determined by enzyme digestion and transfection efficiency were equivalent to the expensive commercial kits. Importantly, the time required for purification was much less than that required using a commercial kit. CONCLUSIONS/SIGNIFICANCE: This method provides DNA yield and quality similar to that obtained with commercial kits, but is more rapid and less costly.

  20. On Rural Financial and Accounting Work under the Background of Rapid Agricultural Economic Development

    Institute of Scientific and Technical Information of China (English)

    Yaozheng; TANG

    2013-01-01

    Under the background of rapid agricultural economic development,rural financial and accounting work is of great significance. From rural accounting management system,rural accountant allocation and rural accounting training,this paper analyzes current situations of rural accounting work in China. In rural financial and accounting work,there are following problems. ( 1) Accounting behavior is not standard,and basic accounting work is to be further strengthened; ( 2) Internal control is not perfect and implementation of supervision mechanism is formalized; ( 3) Few people manipulate accounting behavior and accounting information is not transparent. In view of these problems,it puts forward countermeasures for improving rural accounting work: ( 1) establishing perfect agricultural accounting system; ( 2) regulating fund management order; ( 3) promoting computerized agricultural financial and accounting work; ( 4) improving professional and comprehensive quality of rural accountants.

  1. Can organic crops increase the economic potential for biorefineries?

    OpenAIRE

    Gylling, Morten; Jakobsen, Anders B.

    2017-01-01

    With the current cost and price relations, the profitability of biorefineries is still challenged. The use of organic crops, such as grass, in biorefineries can increase the profitability because organic products can be sold at higher prices.

  2. Fertility in Alberta in a Context of Rapid Economic Growth, 1997-2007

    Directory of Open Access Journals (Sweden)

    Frank Trovato

    2010-12-01

    Full Text Available Historically, birth rates in Alberta have followed closely the trajectory of change experienced by the other Canadian provinces. Its total fertility rate fell during the low point of the 1930s; it increased during the post-War baby boom in the 1950s and sixties, and thereafter fell to subreplacement levels beginning in the mid 1970s. In recent years, especially since the early 2000s, the birth rate in Alberta has unexpectedly increased, such that by 2007, it had reached 1.90 children per woman - not far from the 2.1 level needed for generational replacement in the long term. During this same period both national and provincial fertility rates fluctuated at levels below those of Alberta (except Saskatchewan and Manitoba, whose rates have been higher. In this study, I examine the historical pattern of fertility change in Alberta, noting similarities and differences with the other provinces. I then look at the association of selected macro level factors (marriage, unemployment, wages, female labour force participation with change in total and parity-specific birth rates between 1997 and 2007, a period of unprecedented economic growth in Alberta. The statistical results show that although marriage is not significantly correlated with change in fertility rates, male and female wages and female labour force participation all show associations consistent with a procyclical interpretation of fertility change - that is, periods of economic growth are conducive to fertility increase whereas bad economic times are associated with reduced fertility.

  3. Fertility in Alberta in a Context of Rapid Economic Growth, 1997-2007

    Directory of Open Access Journals (Sweden)

    Frank Trovato

    2010-01-01

    Full Text Available Historically, birth rates in Alberta have followed closely the trajectory of change experienced by the other Canadian provinces. Its total fertility rate fell during the low point of the 1930s; it increased during the post-War baby boom in the 1950s and sixties, and thereafter fell to sub-replacement levels beginning in the mid 1970s. In recent years, especially since the early 2000s, the birth rate in Alberta has unexpectedly increased, such that by 2007, it had reached 1.90 children per woman---not far from the 2.1 level needed for generational replacement in the long term. During this same period both national and provincial fertility rates fluctuated at levels below those of Alberta (except Saskatchewan and Manitoba, whose rates have been higher. In this study, I examine the historical pattern of fertility change in Alberta, noting similarities and differences with the other provinces. I then look at the association of selected macro level factors (marriage, unemployment, wages, female labour force participation with change in total and parity-specific birth rates between 1997 and 2007, a period of unprecedented economic growth in Alberta. The statistical results show that although marriage is not significantly correlated with change in fertility rates, male and female wages and female labour force participation all show associations consistent with a procyclical interpretation of fertility change --- that is, periods of economic growth are conducive to fertility increase whereas bad economic times lead to reduced fertility.

  4. Increased corrosion resistance of the AZ80 magnesium alloy by rapid solidification.

    Science.gov (United States)

    Aghion, E; Jan, L; Meshi, L; Goldman, J

    2015-11-01

    Magnesium (Mg) and Mg-alloys are being considered as implantable biometals. Despite their excellent biocompatibility and good mechanical properties, their rapid corrosion is a major impediment precluding their widespread acceptance as implantable biomaterials. Here, we investigate the potential for rapid solidification to increase the corrosion resistance of Mg alloys. To this end, the effect of rapid solidification on the environmental and stress corrosion behavior of the AZ80 Mg alloy vs. its conventionally cast counterpart was evaluated in simulated physiological electrolytes. The microstructural characteristics were examined by optical microscopy, SEM, TEM, and X-ray diffraction analysis. The corrosion behavior was evaluated by immersion, salt spraying, and potentiodynamic polarization. Stress corrosion resistance was assessed by Slow Strain Rate Testing. The results indicate that the corrosion resistance of rapidly solidified ribbons is significantly improved relative to the conventional cast alloy due to the increased Al content dissolved in the α-Mg matrix and the correspondingly reduced presence of the β-phase (Mg17 Al12 ). Unfortunately, extrusion consolidated solidified ribbons exhibited a substantial reduction in the environmental performance and stress corrosion resistance. This was mainly attributed to the detrimental effect of the extrusion process, which enriched the iron impurities and increased the internal stresses by imposing a higher dislocation density. In terms of immersion tests, the average corrosion rate of the rapidly solidified ribbons was <0.4 mm/year compared with ∼2 mm/year for the conventionally cast alloy and 26 mm/year for the rapidly solidified extruded ribbons. © 2014 Wiley Periodicals, Inc.

  5. Economic impact of the energy price increase in Mexico

    International Nuclear Information System (INIS)

    Uri, N.D.; Boyd, R.

    1997-01-01

    One unknown with regard to the price increases for gasoline and electricity is what will be the expected impact as the Mexican economy struggles to rebound. This is of more than spurious concern since many Mexican industries rely both intensively and extensively on gasoline and electricity to produce their goods and services. For example, the petrochemical and steel manufacturing industries are major consumers in Mexico's industrial sector which accounts for 55% of total energy consumption. Mexico's steel industry is one of the most electricity intensive in the world, with heavy reliance on electric arc furnace technology. Mexico's transportation sector accounts for about 30% of total energy consumption. Higher energy prices are expected to affect significantly the price and quantity of the goods and services produced. The nature and extent of this effect is the subject of this article. Also the modelling approach to be used in assessing the impact of higher energy prices will be discussed. 2 tabs., 20 refs

  6. Pilot testing a methodology to measure the marginal increase in economic impact of rural tourism sites

    Science.gov (United States)

    April Evans; Hans Vogelsong

    2008-01-01

    Rural tourism is a rapidly expanding industry which holds some promise of improving the economy in small towns and farming regions. However, rural communities have limited funding available for promotional efforts. To understand if limited funds are effective in producing the desired economic impacts, it is important that rural communities evaluate their promotional...

  7. Water Quality Changes during Rapid Urbanization in the Shenzhen River Catchment: An Integrated View of Socio-Economic and Infrastructure Development

    Directory of Open Access Journals (Sweden)

    Hua-peng Qin

    2014-10-01

    Full Text Available Surface water quality deterioration is a serious problem in many rapidly urbanizing catchments in developing countries. There is currently a lack of studies that quantify water quality variation (deterioration or otherwise due to both socio-economic and infrastructure development in a catchment. This paper investigates the causes of water quality changes over the rapid urbanization period of 1985–2009 in the Shenzhen River catchment, China and examines the changes in relation to infrastructure development and socio-economic policies. The results indicate that the water quality deteriorated rapidly during the earlier urbanization stages before gradually improving over recent years, and that rapid increases in domestic discharge were the major causes of water quality deterioration. Although construction of additional wastewater infrastructure can significantly improve water quality, it was unable to dispose all of the wastewater in the catchment. However, it was found that socio-economic measures can significantly improve water quality by decreasing pollutant load per gross regional production (GRP or increasing labor productivity. Our findings suggest that sustainable development during urbanization is possible, provided that: (1 the wastewater infrastructure should be constructed timely and revitalized regularly in line with urbanization, and wastewater treatment facilities should be upgraded to improve their nitrogen and phosphorus removal efficiencies; (2 administrative regulation policies, economic incentives and financial policies should be implemented to encourage industries to prevent or reduce the pollution at the source; (3 the environmental awareness and education level of local population should be increased; (4 planners from various sectors should consult each other and adapt an integrated planning approach for socio-economic and wastewater infrastructure development.

  8. Rapid Increase of Genetically Diverse Methicillin-Resistant Staphylococcus aureus, Copenhagen, Denmark

    DEFF Research Database (Denmark)

    Bartels, Mette Damkjær; Boye, Kit; Larsen, Anders Rhod

    2007-01-01

    In Copenhagen, methicillin-resistant Staphylococcus aureus (MRSA) accounted for <15 isolates per year during 1980-2002. However, since 2003 an epidemic increase has been observed, with 33 MRSA cases in 2003 and 110 in 2004. We analyzed these 143 cases epidemiologically and characterized isolates ...... and soft tissue infections dominated. CO-MRSA with diverse genetic backgrounds is rapidly emerging in a low MRSA prevalence area. Udgivelsesdato: October...

  9. Rapid increase in cystic volume of an anaplastic astrocytoma misdiagnosed as neurocysticercosis: A case report

    Science.gov (United States)

    Li, Hong-Jiang; Han, Hong-Xiu; Feng, Dong-Fu

    2016-01-01

    Reports describing a rapid increase in the cystic volume of anaplastic astrocytoma (AA) in a short time frame are rare. The present study reports the case of a 68-year-old male who was admitted to the No. 9 People's Hospital, Shanghai Jiaotong University School of Medicine (Shanghai, China), with a small cystic brain lesion and positive immunological testing for cysticercosis. Head magnetic resonance imaging (MRI) showed a cystic lesion, 6 mm in diameter, in the left frontal lobe. Neurocysticercosis was suspected and the patient was treated with a clinical trial of albendazole and steroids. A period of 25 days later, the patient's condition had deteriorated, and MRI revealed a cystic lesion in the left frontal lobe; thereafter, the cystic lesion was removed and a diagnosis of AA was established. The tumor was soft, ivory white and gelatinous due to myxoid degeneration. In this case, tumor-related angiogenesis and microvascular extravasation (blood-brain barrier disruption) may have been the main cause of the rapid increase in the cystic volume in such a short time frame. The similarity of the glioma and cysticercus antigens may have been the cause of the positive reactions in the cystic fluid. The present study reports the rare occurrence of a rapid increase of cystic volume and potential diagnostic difficulties. PMID:27698865

  10. SOCIAL INEQUALITY IN CHINA AS A RESULT OF THE RAPID ECONOMIC GROWTH

    Directory of Open Access Journals (Sweden)

    Вероника Игоревна Шехурдина

    2013-12-01

    Full Text Available Since the period of openness in China, laid the foundation for more than 30 years ago, he has made remarkable progress in increasing incomes and reducing absolute poverty. However, they are caused by rising inequality. It should be noted that the rise in inequality was seen almost everywhere in the world over the past two decades. Growing dissatisfaction with the quality of economic growth is often seen in favor of certain groups more than the general population. This is clearly reflected in the growth of inequality between different groups - the rich are getting richer faster than the poor. The economic literature attributes this mainly to globalization, technological change, skills-based, and reduce the "power" of the workers. Growth model, which accompanies the last three decades to China, included a trade-off between high growth (and subsequent reduction of absolute poverty and worsening inequality. The government of China has recognized this problem and taken active steps to reduce the gap incomes and standards of living in the city and rural areas, which have already brought the first results.DOI: http://dx.doi.org/10.12731/2218-7405-2013-10-16

  11. Rapid

    Directory of Open Access Journals (Sweden)

    Nahla M. Wassim

    2013-01-01

    Full Text Available Members of Aedes caspius mosquitoes are incriminated to be a potential reservoir of “Rift Valley Fever Virus” (RVF during interepizootic periods in Egypt. Ae. caspius contains two distinct forms which are morphologically indistinguishable but differ in physiology and behavior; Ae. caspius form (a requires a blood meal for each egg batch(anautogeny, is unable to mate in confined spaces(eurygamous. The second form (b lays egg batch without blood meal (autogenous and can mate in confined spaces (stenogamous. In this work, we collected the autogenous and anautogenous forms of Ae. caspius from two different breeding habitats in the Qalyubia Governorate. Analysis of the Drosophila ace-Orthologous acetylecholinesterase gene revealed that a single polymorphic region characterized each species. Based on this region, specific primers were used to amplify the entire section of intron II, sections of Exon 2 and Exon 3 of ace-2 gene for differentiating the complex species of mosquitoes. The amplicons of anautogenous form sized 441 pb and increase 116 bp than autogenous form of Ae. caspius. High rates of point mutations were addressed; deletion/insertion events are 120 bases. The transversion mutations were 44 bases and were relatively close to the transtion mutations 43 base. The genetic distance was 0.01 between the two forms.

  12. Increasing the Economical Efficiency and Sustainability of Indoor Fish Farming by Means of Aquaponics - Review

    Directory of Open Access Journals (Sweden)

    Flavius Blidariu

    2011-10-01

    Full Text Available This review focuses on increasing economical efficiency and sustainability of indoor fish farming. Aspects like sustainability and economical efficiency were reviewed. In order to improve man`s health we must reconsider the agricultural sciences, by this we understand that we must develop technologies friendly for the environment. Sustainable indoor fish farming is the farming of the new millennium. Combining aquaculture with hydroponics we obtain a new innovation named aquaponics which respects principles of sustainable agriculture (wastewater biofiltration by plants and gives us the possibility to increase economical efficiency with an additional production (organic vegetables.

  13. Exogenous Testosterone Rapidly Increases Aggressive Behavior in Dominant and Impulsive Men.

    Science.gov (United States)

    Carré, Justin M; Geniole, Shawn N; Ortiz, Triana L; Bird, Brian M; Videto, Amber; Bonin, Pierre L

    2017-08-15

    Although traditional wisdom suggests that baseline levels of testosterone (T) promote aggressive behavior, decades of research have produced findings that have been largely weak and inconsistent. However, more recent experimental work suggests that exogenous administration of T rapidly potentiates amygdala and hypothalamus responses to angry facial expressions. Notably, these brain regions are rich in androgen receptors and play a key role in modulating aggressive behavior in animal models. The present experiment extends this work by examining whether acutely increasing T potentiates aggressive behavior in men. In a double-blind, placebo-controlled, between-subject design, healthy adult men (n = 121) were administered either T or placebo, and subsequently engaged in a well-validated decision-making game that measures aggressive behavior in response to social provocation. In light of prior correlational research, we also assessed the extent to which T's effects on aggressive behavior would depend on variability in trait dominance and/or trait self-control. Exogenous T on its own did not modulate aggressive behavior. However, T's effects on aggression were strongly influenced by variation in trait dominance and trait self-control. Specifically, T caused an increase in aggressive behavior, but only among men scoring relatively high in trait dominance or low in trait self-control. These findings are the first to demonstrate that T can rapidly (within 60 minutes) potentiate aggressive behavior, but only among men with dominant or impulsive personality styles. Copyright © 2016 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  14. Rapid Environmental Change Drives Increased Land Use by an Arctic Marine Predator.

    Directory of Open Access Journals (Sweden)

    Todd C Atwood

    Full Text Available In the Arctic Ocean's southern Beaufort Sea (SB, the length of the sea ice melt season (i.e., period between the onset of sea ice break-up in summer and freeze-up in fall has increased substantially since the late 1990s. Historically, polar bears (Ursus maritimus of the SB have mostly remained on the sea ice year-round (except for those that came ashore to den, but recent changes in the extent and phenology of sea ice habitat have coincided with evidence that use of terrestrial habitat is increasing. We characterized the spatial behavior of polar bears spending summer and fall on land along Alaska's north coast to better understand the nexus between rapid environmental change and increased use of terrestrial habitat. We found that the percentage of radiocollared adult females from the SB subpopulation coming ashore has tripled over 15 years. Moreover, we detected trends of earlier arrival on shore, increased length of stay, and later departure back to sea ice, all of which were related to declines in the availability of sea ice habitat over the continental shelf and changes to sea ice phenology. Since the late 1990s, the mean duration of the open-water season in the SB increased by 36 days, and the mean length of stay on shore increased by 31 days. While on shore, the distribution of polar bears was influenced by the availability of scavenge subsidies in the form of subsistence-harvested bowhead whale (Balaena mysticetus remains aggregated at sites along the coast. The declining spatio-temporal availability of sea ice habitat and increased availability of human-provisioned resources are likely to result in increased use of land. Increased residency on land is cause for concern given that, while there, bears may be exposed to a greater array of risk factors including those associated with increased human activities.

  15. Rapid economic growth leads to boost in NO2 pollution over India, as seen from space

    Science.gov (United States)

    Hilboll, Andreas; Richter, Andreas; Burrows, John P.

    2016-04-01

    Over the past decades, the Indian economy has been growing at an exceptional pace. This growth was induced and accompanied by a strong increase of the Indian population. Consequently, traffic, electricity consumption, and industrial production have soared over the past decades, leading to a strong increase in fuel consumption and thus pollutant emissions. Nitrogen oxides (NO+NO2) are a major component of anthropogenic air pollution, playing key part in reaction cycles leading to the formation of tropospheric ozone. They are mainly emitted by the combustion of fossil fuels; other sources include production by lightning, biomass burning, and microbial activity in soils. Since the mid-1990s, space-borne measurements of tropospheric nitrogen dioxide (NO2) have been conducted by the GOME, SCIAMACHY, GOME-2, and OMI instruments. These instruments perform hyperspectral measurements of scattered and reflected sunlight. Their measurements are then analyzed using differential optical absorption spectroscopy (DOAS) to yield vertically integrated columnar trace gas abundances. Here, we will present the results of 20 years of NO2 measurements over the Indian subcontinent. After showing the spatial distribution of NO2 pollution over India, we will present time series for individual states and urban agglomerations. These time series will then be related to various indicators of economic development. Finally, we will highlight several instances where single industrial pollution sources and their development can clearly be identified from the NO2 maps and estimate their NO2 emissions.

  16. Income Inequality Explains Why Economic Growth Does Not Always Translate to an Increase in Happiness.

    Science.gov (United States)

    Oishi, Shigehiro; Kesebir, Selin

    2015-10-01

    One of the most puzzling social science findings in the past half century is the Easterlin paradox: Economic growth within a country does not always translate into an increase in happiness. We provide evidence that this paradox can be partly explained by income inequality. In two different data sets covering 34 countries, economic growth was not associated with increases in happiness when it was accompanied by growing income inequality. Earlier instances of the Easterlin paradox (i.e., economic growth not being associated with increasing happiness) can thus be explained by the frequent concurrence of economic growth and growing income inequality. These findings suggest that a more even distribution of growth in national wealth may be a precondition for raising nationwide happiness. © The Author(s) 2015.

  17. Clustered lot quality assurance sampling to assess immunisation coverage: increasing rapidity and maintaining precision.

    Science.gov (United States)

    Pezzoli, Lorenzo; Andrews, Nick; Ronveaux, Olivier

    2010-05-01

    Vaccination programmes targeting disease elimination aim to achieve very high coverage levels (e.g. 95%). We calculated the precision of different clustered lot quality assurance sampling (LQAS) designs in computer-simulated surveys to provide local health officers in the field with preset LQAS plans to simply and rapidly assess programmes with high coverage targets. We calculated sample size (N), decision value (d) and misclassification errors (alpha and beta) of several LQAS plans by running 10 000 simulations. We kept the upper coverage threshold (UT) at 90% or 95% and decreased the lower threshold (LT) progressively by 5%. We measured the proportion of simulations with d unvaccinated individuals if the coverage was LT% (pLT) to calculate alpha (1-pLT). We divided N in clusters (between 5 and 10) and recalculated the errors hypothesising that the coverage would vary in the clusters according to a binomial distribution with preset standard deviations of 0.05 and 0.1 from the mean lot coverage. We selected the plans fulfilling these criteria: alpha LQAS plans dividing the lot in five clusters with N = 50 (5 x 10) and d = 4 to evaluate programmes with 95% coverage target and d = 7 to evaluate programmes with 90% target. These plans will considerably increase the feasibility and the rapidity of conducting the LQAS in the field.

  18. Thermodynamic balance of photosynthesis and transpiration at increasing CO2 concentrations and rapid light fluctuations.

    Science.gov (United States)

    Marín, Dolores; Martín, Mercedes; Serrot, Patricia H; Sabater, Bartolomé

    2014-02-01

    Experimental and theoretical flux models have been developed to reveal the influence of sun flecks and increasing CO2 concentrations on the energy and entropy balances of the leaf. The rapid and wide range of fluctuations in light intensity under field conditions were simulated in a climatic gas exchange chamber and we determined the energy and entropy balance of the leaf based on radiation and gas exchange measurements. It was estimated that the energy of photosynthetic active radiation (PAR) accounts for half of transpiration, which is the main factor responsible for the exportation of the entropy generated in photosynthesis (Sg) out of the leaf in order to maintain functional the photosynthetic machinery. Although the response of net photosynthetic production to increasing concentrations of CO2 under fluctuating light is similar to that under continuous light, rates of transpiration respond slowly to changes of light intensity and are barely affected by the concentration of CO2 in the range of 260-495 ppm, in which net photosynthesis increases by more than 100%. The analysis of the results confirms that future increases of CO2 will improve the efficiency of the conversion of radiant energy into biomass, but will not reduce the contribution of plant transpiration to the leaf thermal balance. Copyright © 2013 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  19. Rapidly Increasing Trend of Recorded Alcohol Consumption Since the End of the Armed Conflict in Sri Lanka.

    Science.gov (United States)

    Nugawela, Manjula D; Lewis, Sarah; Szatkowski, Lisa; Langley, Tessa

    2017-09-01

    To evaluate temporal changes in recorded alcohol consumption in Sri Lanka during and after the armed conflict 1998-2013. District level alcohol sales, and mid-year population data for the whole study period (1998-2013) were consistently available from the Department of Excise and the Department of Census and Statistics for 18 of 25 districts. These data were used to estimate the recorded per capita consumption for the areas that were not directly exposed to the armed conflict. An interrupted time series design was employed to estimate the impact of the end of the armed conflict on recorded adult per capita alcohol consumption of population lived in the 18 districts. Adult per capita recorded alcohol consumption among Sri Lankans living in the 18 districts was 1.59 l of pure alcohol in 1998. This increased up to 2.07 l in 2009 and 2.55 l in 2013. Prior to the end of the conflict in 2009 adult per capita recorded consumption increased by 0.051 l of pure alcohol per year (95% CI: 0.029-0.074, P increased markedly after the end of the conflict. Rapid socio-economic development, alcohol industry penetration and lack of alcohol control strategies during the post-conflict period may have driven this increase. Adult per capita recorded alcohol consumption among Sri Lankans living in 18 districts that were not directly exposed to the armed conflict increased markedly after the end of the conflict in 2009, with a dramatic acceleration in the trend of per capita beer consumption. © The Author 2017. Medical Council on Alcohol and Oxford University Press. All rights reserved.

  20. THE ROLE OF INTERNATIONAL INNOVATION CLUSTERS ON INCREASING ECONOMIC AGENTS SUSTAINABILITY

    Directory of Open Access Journals (Sweden)

    M. Ustymenko

    2014-09-01

    Full Text Available The influence of enterprises integration into international innovation clusters on the increasing of enterprises, countries and regions economic sustainability under the global instability are explored. Potential sources of instability and threats of the integration into international cluster structures are defined. Author outlines the main benefits of international innovation cluster for enhancement of economic agents sustainability, such as: possibility for joint exploitation of market opportunities and efforts consolidation for overcoming market threats, cluster self-sufficiency, effective cluster internal reorganization and adaptation in response to external changes. Three clusters (engineering for agriculture production cluster (Hersonska oblast and German enterprises, IT cluster (Lvivska oblast and Poland enterprises, cluster for R&D commercialization (Slobodzanschina euroregion are examined to uncover the role of international innovation cluster formation on enhancement of economic agents' economic sustainability.

  1. Rapid increase in the use of oral antidiabetic drugs in the United States, 1990-2001.

    Science.gov (United States)

    Wysowski, Diane K; Armstrong, George; Governale, Laura

    2003-06-01

    To describe the use of oral antidiabetic drugs for management of type 2 diabetes in the U.S. from 1990 through 2001. Data on oral antidiabetic drugs were derived from two pharmaceutical marketing databases from IMS Health, the National Prescription Audit Plus and the National Disease and Therapeutic Index. In 1990, 23.4 million outpatient prescriptions of oral antidiabetic agents were dispensed. By 2001, this number had increased 3.9-fold, to 91.8 million prescriptions. Glipizide and glyburide, two sulfonylurea medications, accounted for approximately 77% of prescriptions of oral antidiabetic drugs in 1990 and 35.5% of prescriptions in 2001. By 2001, the biguanide metformin (approved in 1995) had captured approximately 33% of prescriptions, and the thiazolidinedione insulin sensitizers (rosiglitazone and pioglitazone marketed beginning in 1999) accounted for approximately 17% of market share. Compared with patients treated in 1990, those in 2001 were proportionately younger and they more often used oral antidiabetic drugs and insulin in combination. Internists and general and family practitioners were the primary prescribers of this class of drugs. Consistent with the reported increase in the prevalence of type 2 diabetes, the number of dispensed outpatient prescriptions of oral antidiabetic drugs increased rapidly between 1990 and 2001. This period was marked by an increase in the treatment of younger people and the use of oral antidiabetic drugs in combination. With the approval in the last decade of several new types of oral antidiabetic medications with different mechanisms of action, options for management of type 2 diabetes have expanded.

  2. Economic Impact of Tobacco Price Increases Through Taxation: A Community Guide Systematic Review.

    Science.gov (United States)

    Contreary, Kara A; Chattopadhyay, Sajal K; Hopkins, David P; Chaloupka, Frank J; Forster, Jean L; Grimshaw, Victoria; Holmes, Carissa B; Goetzel, Ron Z; Fielding, Jonathan E

    2015-11-01

    Tobacco use is a leading cause of preventable death in the U.S. and around the world. Increasing tobacco price through higher taxes is an effective intervention both to reduce tobacco use in the population and generate government revenues. The goal of this paper is to review evidence on the economic impact of tobacco price increases through taxation with a focus on the likely healthcare cost savings and improvements in employee productivity. The search covered studies published in English from January 2000 to July 2012 and included evaluations of national, state, and local policies to increase the price of any type of tobacco product by raising taxes in high-income countries. Economic review methods developed for The Guide to Community Preventive Services were used to screen and abstract included studies. Economic impact estimates were standardized to summarize the available evidence. Analyses were conducted in 2012. The review included eight modeling studies, with seven providing estimates of the impact on healthcare costs and three providing estimates of the value of productivity gains. Only one study provided an estimate of intervention costs. The economic merit of tobacco product price increases through taxation was determined from the overall body of evidence on per capita annual cost savings from a conservative 20% price increase. The evidence indicates that interventions that raise the unit price of tobacco products through taxes generate substantial healthcare cost savings and can generate additional gains from improved productivity in the workplace. Published by Elsevier Inc.

  3. Explaining the Rapid Increase in Nigeria's Sex Ratio at Birth: Factors and Implications.

    Science.gov (United States)

    Kaba, Amadu J

    2015-06-01

    This paper examines the rapid increase in Nigeria's sex ratio at birth from 1.03 boys born for every 1 girl born in each year from 1996-2008 to 1.06 in each year from 2009-2014, second only to Tunisia in Africa at 1.07. The average sex ratio at birth in the world in 2014 was 1.07. In most Black African nations or Black majority nations, it is 1.03 or less. Among the factors presented for this development are: historical fluctuations of sex ratio at birth; geography and ethnicity; male preference/chasing a son; Age of parents; high death rates of male infants and males in general; and wealth/socioeconomic status. Among the potential implications are: young and poor men in Nigeria may not be able to find brides and form families due to a potential shortage of females; emigration of young and poor Nigerian men to West (Africa) and elsewhere to seek brides and form families; immigration of marriage age women from West (Africa) and around the world to Nigeria to seek husbands; and low contraceptive use and high fertility rates in Nigeria.

  4. Rapid increase of near atomic resolution virus capsid structures determined by cryo-electron microscopy.

    Science.gov (United States)

    Ho, Phuong T; Reddy, Vijay S

    2018-01-01

    The recent technological advances in electron microscopes, detectors, as well as image processing and reconstruction software have brought single particle cryo-electron microscopy (cryo-EM) into prominence for determining structures of bio-molecules at near atomic resolution. This has been particularly true for virus capsids, ribosomes, and other large assemblies, which have been the ideal specimens for structural studies by cryo-EM approaches. An analysis of time series metadata of virus structures on the methods of structure determination, resolution of the structures, and size of the virus particles revealed a rapid increase in the virus structures determined by cryo-EM at near atomic resolution since 2010. In addition, the data highlight the median resolution (∼3.0 Å) and size (∼310.0 Å in diameter) of the virus particles determined by X-ray crystallography while no such limits exist for cryo-EM structures, which have a median diameter of 508 Å. Notably, cryo-EM virus structures in the last four years have a median resolution of 3.9 Å. Taken together with minimal sample requirements, not needing diffraction quality crystals, and being able to achieve similar resolutions of the crystal structures makes cryo-EM the method of choice for current and future virus capsid structure determinations. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Rapid eye movement sleep deprivation induces an increase in acetylcholinesterase activity in discrete rat brain regions

    Directory of Open Access Journals (Sweden)

    Benedito M.A.C.

    2001-01-01

    Full Text Available Some upper brainstem cholinergic neurons (pedunculopontine and laterodorsal tegmental nuclei are involved in the generation of rapid eye movement (REM sleep and project rostrally to the thalamus and caudally to the medulla oblongata. A previous report showed that 96 h of REM sleep deprivation in rats induced an increase in the activity of brainstem acetylcholinesterase (Achase, the enzyme which inactivates acetylcholine (Ach in the synaptic cleft. There was no change in the enzyme's activity in the whole brain and cerebrum. The components of the cholinergic synaptic endings (for example, Achase are not uniformly distributed throughout the discrete regions of the brain. In order to detect possible regional changes we measured Achase activity in several discrete rat brain regions (medulla oblongata, pons, thalamus, striatum, hippocampus and cerebral cortex after 96 h of REM sleep deprivation. Naive adult male Wistar rats were deprived of REM sleep using the flower-pot technique, while control rats were left in their home cages. Total, membrane-bound and soluble Achase activities (nmol of thiocholine formed min-1 mg protein-1 were assayed photometrically. The results (mean ± SD obtained showed a statistically significant (Student t-test increase in total Achase activity in the pons (control: 147.8 ± 12.8, REM sleep-deprived: 169.3 ± 17.4, N = 6 for both groups, P<0.025 and thalamus (control: 167.4 ± 29.0, REM sleep-deprived: 191.9 ± 15.4, N = 6 for both groups, P<0.05. Increases in membrane-bound Achase activity in the pons (control: 171.0 ± 14.7, REM sleep-deprived: 189.5 ± 19.5, N = 6 for both groups, P<0.05 and soluble enzyme activity in the medulla oblongata (control: 147.6 ± 16.3, REM sleep-deprived: 163.8 ± 8.3, N = 6 for both groups, P<0.05 were also observed. There were no statistically significant differences in the enzyme's activity in the other brain regions assayed. The present findings show that the increase in Achase activity

  6. Sugammadex for reversal of neuromuscular block after rapid sequence intubation: a systematic review and economic assessment†

    Science.gov (United States)

    Chambers, D.; Paulden, M.; Paton, F.; Heirs, M.; Duffy, S.; Hunter, J. M.; Sculpher, M.; Woolacott, N.

    2010-01-01

    Summary Sugammadex 16 mg kg−1 can be used for the immediate reversal of neuromuscular block 3 min after administration of rocuronium and could be used in place of succinylcholine for emergency intubation. We have systematically reviewed the efficacy and cost-effectiveness and made an economic assessment of sugammadex for immediate reversal. The economic assessment investigated whether sugammadex appears cost-effective under various assumptions about the value of any reduction in recovery time with sugammadex, the likelihood of a ‘can't intubate, can't ventilate’ (CICV) event, the age of the patient, and the length of the procedure. Three trials were included in the efficacy review. Sugammadex administered 3 or 5 min after rocuronium produced markedly faster recovery than placebo or spontaneous recovery from succinylcholine-induced block. No published economic evaluations were found. Our economic analyses showed that sugammadex appears more cost-effective, where the value of any reduction in recovery time is greater, where the reduction in mortality compared with succinylcholine is greater, and where the patient is younger, for lower probabilities of a CICV event and for long procedures which do not require profound block throughout. Because of the lack of evidence, the value of some parameters remains unknown, which makes it difficult to provide a definitive assessment of the cost-effectiveness of sugammadex in practice. The use of sugammadex in combination with high-dose rocuronium is efficacious. Further research is needed to clarify key parameters in the analysis and to allow a fuller economic assessment. PMID:20937718

  7. The impact of the 2008 economic crisis on the increasing number of young psychiatric inpatients.

    Science.gov (United States)

    Medel-Herrero, Alvaro; Gomez-Beneyto, Manuel

    2017-11-21

    Little is published about the impact of the 2008 economic crisis on mental health services in Spain. An interrupted time series analysis was conducted to investigate a potential short-term association between the 2008 economic crisis and the number of psychiatric hospital admissions. The timing of the intervention (April 2008) was based on observed changes in Gross Domestic Product (GDP). Data on 1,152,880 psychiatric inpatients from the national Hospital Morbidity Survey, 69 months before and after the onset of the economic crisis (April 2008), were analyzed. Age-adjusted psychiatric (ICD9 290-319) hospital discharge rates significantly increased from April 2008, matching the onset of the crisis, especially for inpatients aged 15-24 years old and to a less extend for inpatients aged 25-34 years old. Other age groups were not affected. There was a significant increase in diagnoses for disturbance of conduct and emotions, depression, neurotic and personality disorders and alcohol and drug disorders; however, diagnoses for mental retardation and organic psychosis for 15-34 years old inpatients were unaffected. Psychiatric hospital admissions abruptly increased in April 2008, coinciding with the onset of the economic crisis. We identified age groups and diagnoses affected. Increased hospitalizations were found only at the age-ranges most affected by the rise in unemployment. The diagnoses affected were those most sensitive to environmental changes. Copyright © 2017 SEP y SEPB. Publicado por Elsevier España, S.L.U. All rights reserved.

  8. RAPID KNEE-EXTENSIONS TO INCREASE QUADRICEPS MUSCLE ACTIVITY IN PATIENTS WITH TOTAL KNEE ARTHROPLASTY

    DEFF Research Database (Denmark)

    Husted, Rasmus Skov; Wilquin, Lousia; Jakobsen, Thomas Linding

    2017-01-01

    rapid knee-extensions were associated with greater voluntary quadriceps muscle activity during an experimental strength training session, compared to that elicited using slow knee-extensions. STUDY DESIGN: A randomized cross-over study. METHODS: Twenty-four patients (age 66.5) 4-8 weeks post total knee...... agonist muscle activity, especially if the exercise is conducted using rapid muscle contractions. PURPOSE: The purpose of this study was to examine if patients with total knee arthroplasty could perform rapid knee-extensions using a 10 RM load four to eight weeks after surgery, and the degree to which...... arthroplasty randomly performed one set of five rapid, and one set of five slow knee-extensions with the operated leg, using a load of their 10 repetition maximum, while surface electromyography recordings were obtained from the vastus medialis and lateralis of the quadriceps muscle. RESULTS: Data from 23...

  9. Rapid knee-extensions to increase quadriceps muscle activity in patients with total knee arthroplasty

    DEFF Research Database (Denmark)

    Husted, Rasmus Skov; Wilquin, Lousia; Jakobsen, Thomas Linding

    2017-01-01

    rapid knee-extensions were associated with greater voluntary quadriceps muscle activity during an experimental strength training session, compared to that elicited using slow knee-extensions. STUDY DESIGN: A randomized cross-over study. METHODS: Twenty-four patients (age 66.5) 4-8 weeks post total knee...... agonist muscle activity, especially if the exercise is conducted using rapid muscle contractions. PURPOSE: The purpose of this study was to examine if patients with total knee arthroplasty could perform rapid knee-extensions using a 10 RM load four to eight weeks after surgery, and the degree to which...... arthroplasty randomly performed one set of five rapid, and one set of five slow knee-extensions with the operated leg, using a load of their 10 repetition maximum, while surface electromyography recordings were obtained from the vastus medialis and lateralis of the quadriceps muscle. RESULTS: Data from 23...

  10. Economic expansion and increase in labout market formality: a poaching approach

    Directory of Open Access Journals (Sweden)

    Carlos Henrique L. Corseuil

    2012-06-01

    Full Text Available This paper investigates the relationship between economic expansion and the degree of formalization for the Brazilian labour market in the recent period. We present a theoretical framework that attempts to explain this relationship through the dynamics of firms hiring strategies. The main predictions are: the share of formal employment rises as the unemployment rate falls, and that the formal-informal wage gap increases, at least at the beginning of the economic expansion. In the empirical part, we use longitudinal microdata from a Brazilian household survey to check whether these two predictions are confirmed. To a large extent our results corroborate both predictions.

  11. Social and environmental determinants of child health in Mongolia across years of rapid economic growth: 2000-2010.

    Science.gov (United States)

    Joshi, Nehal; Bolorhon, Bolormaa; Narula, Indermohan; Zhu, Shihua; Manaseki-Hollan, Semira

    2017-10-30

    To understand the effect of economic growth on health, we investigated the trend in socio-economic and regional determinants of child health in Mongolia. This Central Asian country had the fastest economic growth amongst low and middle-income countries (LMICs) from 2000 to 2010 and a healthcare system in transition. Data was from Mongolian multiple indicator cluster surveys (MICS) in 2000, 2005 and 2010. Child nutrition/growth was measured by height-for-age z-score (HAZ), weight-for-age z-score (WAZ), prevalence of stunted (HAZ economic and environmental health determinants on each outcome in each year; 2000, 2005 and 2010. T-tests were used to measure significant change in HAZ and WAZ over the decade. Overall, from 2000 to 2010, there was a significant improvement (p economic factors increased on both stunting and weight. In 2000, region was a significant determinant: children living in three provinces were significantly more likely to be stunted and less likely to be immunised than Ulaanbaatar, but this was not significant by 2010. By 2010, none of the factors were significant determinants of immunisation in children. In 2000, economic status had no effect on stunting (OR = 0.91; 95%CI:0.49,1.66), however by 2010, children in the poorest economic quintile were 4 times more likely to be stunted than the richest (OR = 0.24; 95% CI:0.13,0.45; p Economic growth in Mongolia from 2000 to 2010 resulted in an increase in the effect of social determinants of child health; whilst focused policy improved access to immunisation. Children with less educated mothers and lower household incomes should be targeted in interventions to reduce health inequity.

  12. Economical Feedback of Increasing Fuel Enrichment on Electricity Cost for VVER-1000

    Directory of Open Access Journals (Sweden)

    Mohammed Saad Dwiddar

    2015-08-01

    Full Text Available A methodology of evaluating the economics of the front-end nuclear fuel cycle with a price change sensitivity analysis for a VVER-1000 reactor core as a case study is presented. The effect of increasing the fuel enrichment and its corresponding reactor cycle length on the energy cost is investigated. The enrichment component was found to represent the highly expenses dynamic component affecting the economics of the front-end fuel cycle. Nevertheless, the increase of the fuel enrichment will increase the reactor cycle length, which will have a positive feedback on the electricity generation cost (cent/KWh. A long reactor operation time with a cheaper energy cost set the nuclear energy as a competitive alternative when compared with other energy sources.

  13. Economic Benefit of Introducing a Bus Rapid Transit (BRT) in Kano State Nigeria

    Science.gov (United States)

    Ahmad, K. A.; Afolabi, S.; Nda, M.; Daura, H. A.

    2018-04-01

    The objective of this study is to know the variables use in quantifying economic benefits of public transport project, contribution of public transport to economic productivity This paper attempts to provide a Road User Cost (RUC) comparison of current usage of Buses and Cars in three different stages which are the present time, do nothing and the introduction of new modes. Vehicle operating cost (VOC), value of time (VOT), pollution cost, accident cost and environmental cost are calculated in other to know the benefits for their abilities to ensure accessibility and mobility, reduce accidents and reduce environmental loss. The study stretch involves an 11.1 km of 2-lane divided carriageway road connecting Kabuga bus stop to Janguza market. Social costs which included accident costs, accident cost of cars (private modes) were found to be 50 times the accident cost of bus accidents. California Air Resource Board (CARB) model was adopted to evaluate Environmental costs. The total road user costs were then obtained to provide comparative evaluation among the study modes. Furthermore, the multiple future scenarios were created to provide understanding about the need for inclusion of other modes. In this regard, this paper provided a framework for the cost evaluation for an urban area and results indicate that buses are more cost-effective in transportation of equivalent number of passengers.

  14. A rapid, efficient, and economic device and method for the isolation and purification of mouse islet cells.

    Directory of Open Access Journals (Sweden)

    Yin Zongyi

    Full Text Available Rapid, efficient, and economic method for the isolation and purification of islets has been pursued by numerous islet-related researchers. In this study, we compared the advantages and disadvantages of our developed patented method with those of commonly used conventional methods (Ficoll-400, 1077, and handpicking methods. Cell viability was assayed using Trypan blue, cell purity and yield were assayed using diphenylthiocarbazone, and islet function was assayed using acridine orange/ethidium bromide staining and enzyme-linked immunosorbent assay-glucose stimulation testing 4 days after cultivation. The results showed that our islet isolation and purification method required 12 ± 3 min, which was significantly shorter than the time required in Ficoll-400, 1077, and HPU groups (34 ± 3, 41 ± 4, and 30 ± 4 min, respectively; P 1000 islets. In summary, the MCT method is a rapid, efficient, and economic method for isolating and purifying murine islet cell clumps. This method overcomes some of the shortcomings of conventional methods, showing a relatively higher quality and yield of islets within a shorter duration at a lower cost. Therefore, the current method provides researchers with an alternative option for islet isolation and should be widely generalized.

  15. Economic impact of rapid diagnostic methods in Clinical Microbiology: Price of the test or overall clinical impact.

    Science.gov (United States)

    Cantón, Rafael; Gómez G de la Pedrosa, Elia

    2017-12-01

    The need to reduce the time it takes to establish a microbiological diagnosis and the emergence of new molecular microbiology and proteomic technologies has fuelled the development of rapid and point-of-care techniques, as well as the so-called point-of-care laboratories. These laboratories are responsible for conducting both techniques partially to response to the outsourcing of the conventional hospital laboratories. Their introduction has not always been accompanied with economic studies that address their cost-effectiveness, cost-benefit and cost-utility, but rather tend to be limited to the unit price of the test. The latter, influenced by the purchase procedure, does not usually have a regulated reference value in the same way that medicines do. The cost-effectiveness studies that have recently been conducted on mass spectrometry in the diagnosis of bacteraemia and the use of antimicrobials have had the greatest clinical impact and may act as a model for future economic studies on rapid and point-of-care tests. Copyright © 2017 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  16. The economic case for low-carbon development in rapidly growing developing world cities: A case study of Palembang, Indonesia

    International Nuclear Information System (INIS)

    Colenbrander, Sarah; Gouldson, Andy; Sudmant, Andrew Heshedahl; Papargyropoulou, Effie

    2015-01-01

    Where costs or risks are higher, evidence is lacking or supporting institutions are less developed, policymakers can struggle to make the case for low-carbon investment. This is especially the case in developing world cities where decision-makers struggle to keep up with the pace and scale of change. Focusing on Palembang in Indonesia, this paper considers the economic case for proactive investment in low-carbon development. We find that a rapidly growing industrial city in a developing country can reduce emissions by 24.1% in 2025, relative to business as usual levels, with investments of USD405.6 million that would reduce energy expenditure in the city by USD436.8 million. Emissions from the regional grid could be reduced by 12.2% in 2025, relative to business as usual trends, with investments of USD2.9 billion that would generate annual savings of USD175 million. These estimates understate the savings from reduced expenditure on energy subsidies and energy infrastructure. The compelling economic case for mainstreaming climate mitigation in this developing country city suggests that the constraints on climate action can be political and institutional rather than economic. There is therefore a need for more effective energy governance to drive the transition to a low-carbon economy. - Highlights: • We evaluate the economic case for low carbon investment in a developing world city. • Cost-effective measures could reduce emissions by 24.1% relative to BAU levels. • These pay for themselves in <1 year and generate savings throughout their lifetime. • Further savings come from reduced expenditure on energy infrastructure, subsidies. • Limitations on climate action seem to be political/institutional – not economic

  17. Increasing economic benefits by load-shifting of electrical heat pumps

    OpenAIRE

    Laveyne, Joannes; Zwaenepoel, Brecht; Van Eetvelde, Greet; Vandevelde, Lieven

    2014-01-01

    Electrical heating is still widely used in the process industry. While the use of immersion heaters for the production of hot water or steam is declining, the adoption rate of electrical heat pumps is increasing rapidly. Heat pumps show great flexibility and potential for energy savings, e.g. through low temperature waste heat recuperation. In combination with thermal storage they also allow for load shifting. Because their main power source is electricity, which up to now cannot be stored ef...

  18. Energy consumption and economic development after the energy price increases of 1973

    International Nuclear Information System (INIS)

    Danielewski, J.

    1993-01-01

    The interdependence between energy consumption and economic development are highlighted in this research, which focuses on energy price rises between 1973 and 1989. Three groups of countries are identified, developing and developed market economies and centrally planned economies. Two areas of interdependence are examined, firstly the dynamic relationship between primary energy consumption growth and real economic growth and secondly the static relationship between primary energy consumption and national income. In the period under review, developing market economies reacted most strongly to higher energy prices, with lower energy consumption while maintaining real growth in the Gross Domestic Product. However developing countries and centrally planned economies increased their energy consumption per unit of national income although the rate of increase slowed after 1975. (UK)

  19. A rapid cosmic-ray increase in BC 3372-3371 from ancient buried tree rings in China.

    Science.gov (United States)

    Wang, F Y; Yu, H; Zou, Y C; Dai, Z G; Cheng, K S

    2017-11-14

    Cosmic rays interact with the Earth's atmosphere to produce 14 C, which can be absorbed by trees. Therefore, rapid increases of 14 C in tree rings can be used to probe previous cosmic-ray events. By this method, three 14 C rapidly increasing events have been found. Plausible causes of these events include large solar proton events, supernovae, or short gamma-ray bursts. However, due to the lack of measurements of 14 C by year, the occurrence frequency of such 14 C rapidly increasing events is poorly known. In addition, rapid increases may be hidden in the IntCal13 data with five-year resolution. Here we report the result of 14 C measurements using an ancient buried tree during the period between BC 3388 and 3358. We found a rapid increase of about 9‰ in the 14 C content from BC 3372 to BC 3371. We suggest that this event could originate from a large solar proton event.

  20. Collateral damage: rapid exposure-induced evolution of pesticide resistance leads to increased susceptibility to parasites.

    Science.gov (United States)

    Jansen, Mieke; Stoks, Robby; Coors, Anja; van Doorslaer, Wendy; de Meester, Luc

    2011-09-01

    Although natural populations may evolve resistance to anthropogenic stressors such as pollutants, this evolved resistance may carry costs. Using an experimental evolution approach, we exposed different Daphnia magna populations in outdoor containers to the carbamate pesticide carbaryl and control conditions, and assessed the resulting populations for both their resistance to carbaryl as well as their susceptibility to infection by the widespread bacterial microparasite Pasteuria ramosa. Our results show that carbaryl selection led to rapid evolution of carbaryl resistance with seemingly no cost when assessed in a benign environment. However, carbaryl-resistant populations were more susceptible to parasite infection than control populations. Exposure to both stressors reveals a synergistic effect on sterilization rate by P. ramosa, but this synergism did not evolve under pesticide selection. Assessing costs of rapid adaptive evolution to anthropogenic stress in a semi-natural context may be crucial to avoid too optimistic predictions for the fitness of the evolving populations. © 2011 The Author(s).

  1. Blend-wall economics. Relaxing US ethanol regulations can lead to increased use of fossil fuels

    International Nuclear Information System (INIS)

    Zhang, Zibin; Qiu, Cheng; Wetzstein, Michael

    2010-01-01

    The US Environmental Protection Agency is currently considering a waiver allowing an increase in the fuel-ethanol blend limit (the 'blend wall') from 10% (E10) up to 15% (E15). Justifications for this waiver are reduced vehicle fuel prices and less consumption of petroleum gasoline leading to energy security. A theoretical examination of this waiver reveals an anomaly where a relaxation of this blend wall elicits a demand response. Under a wide range of elasticities, this demand response can actually increase the consumption of petroleum gasoline and thus lead to greater energy insecurity. The economics supporting this result and associated policy implications are developed and discussed. (author)

  2. Blend-wall economics. Relaxing US ethanol regulations can lead to increased use of fossil fuels

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Zibin [Department of Economics at Zhejiang University, Hangzhou (China); Qiu, Cheng; Wetzstein, Michael [Department of Agricultural and Applied Economics, University of Georgia, Athens, Georgia 30602 (United States)

    2010-07-15

    The US Environmental Protection Agency is currently considering a waiver allowing an increase in the fuel-ethanol blend limit (the 'blend wall') from 10% (E10) up to 15% (E15). Justifications for this waiver are reduced vehicle fuel prices and less consumption of petroleum gasoline leading to energy security. A theoretical examination of this waiver reveals an anomaly where a relaxation of this blend wall elicits a demand response. Under a wide range of elasticities, this demand response can actually increase the consumption of petroleum gasoline and thus lead to greater energy insecurity. The economics supporting this result and associated policy implications are developed and discussed. (author)

  3. Health inequalities during 20 years of rapid economic development in China (1980-2000): a mortality analysis.

    Science.gov (United States)

    Zheng, XiaoYing; Song, XinMing; Chen, Gong; You, YunZhong; Ren, Qiang; Liu, JuFen; Zhang, Lei; Tan, LingFang; Wei, JiHong; Chen, QiuYuan

    2011-08-01

    To examine the influence of China's economic reforms on population health and regional mortality rates. Longitudinal study measuring the mortality trends and their regional variations. Using data from the three most recent national censuses, we used the model life table to adjust the mortality levels within the population for each census, and to calculate life expectancy. We then examined the variation in patterns of mortality and population health by economic status, region and gender from 1980-2000. Life expectancy varied with economic status, province, and gender. Results showed that, although life expectancy in China had increased overall since the early 1980s, regional differences became more pronounced. Life expectancy for populations who live in the eastern coastal provinces are greater than those in the western regions. Differences in life expectancy are primarily related to differences in regional economic development, which in turn exacerbate regional health inequalities. Therefore, it is necessary to improve economic development in less developed regions and to improve health policies and the public health system that address the needs of everyone. Copyright © 2011 The Editorial Board of Biomedical and Environmental Sciences. Published by Elsevier B.V. All rights reserved.

  4. Novel HPTLC and UV-AUC analyses: For simple, economical, and rapid determination of Zileuton racemate

    Directory of Open Access Journals (Sweden)

    Saurabh B. Ganorkar

    2017-03-01

    Full Text Available Novel, simple, rapid and reliable High-Performance Thin-Layer Chromatographic (HPTLC and UV-spectroscopic area under curve (UV-AUC methods were developed and validated for the analysis of zileuton racemate in bulk and in in-house tablet formulation. HPTLC quantitation of zileuton was done by UV detection at 260 nm and analysis was performed on (20 × 10 cm aluminium sheets precoated with silica gel 60-F254 (E. Merck as stationary phase and toluene–methanol–glacial acetic acid (3.5:1.5:0.1 v/v as mobile phase. Quantitation by HPTLC method was performed over the concentration range of 200–1200 ng/band. The HPTLC method resulted into a compact and well resolved band for zileuton at retention factor (Rf of 0.51 ± 0.02. Linear regression analysis data for calibration of HPTLC method represented a good linear relationship with regression coefficient; r2 = 0.997. UV-AUC method was developed using sodium lauryl sulphate (0.05 M as a hydrotropic agent to enhance water solubility and area was determined at a wavelength range in between 248.40 and 271.0 nm. Correlation coefficient for UV-AUC analysis was found to be r2 = 0.999. The developed UV-AUC method depicted a fine linear relationship for zileuton racemate in a concentration range of 2–12 μg/mL. Both the developed methods were validated for precision, robustness, ruggedness, accuracy, sensitivity as per guidelines laid by the International Conference on Harmonisation (ICH. Statistical analysis proved that the developed methods were precise, robust, sensitive and accurate and can be used effectively for the analysis of zileuton in bulk and pharmaceutical formulations.

  5. Social and economic factors of the natural risk increasing: estimation of the Russian regions

    Directory of Open Access Journals (Sweden)

    E. Petrova

    2004-01-01

    Full Text Available This study is an attempt to assess quantitatively social and economic factors that determine vulnerability of Russian regions to natural risk, to trace the space differences of the considered factors, and to group the regions by their similarity. In order to indicate the regional differences in social and economic development, equipment condition, dangerous substances accumulation, and social trouble four the most suitable parameters were estimated, including the per capita production of Gross Regional Product (GRP, capital consumption, volume of total toxic waste, and crime rate. Increase of the first parameter causes vulnerability reducing, the increase of the last three causes its increasing. Using multidimensional cluster analysis five types of regions were found for Russia according to similarity of the considered parameters. These types are characterized with higher value of a single (rarely two chosen parameter, which seems to be sufficient enough to affect natural risks increasing in these regions in near future. Only few regions belonging to the fifth type proved to have rather high value of GRP and relatively low values of the other parameters. The negative correlation was found between a number of natural disasters (ND and the per capita GRP in case when some parameters reached anomalously high value. The distinctions between regions by prevailing different parameters, which result in natural risk increasing, help risk management to find directions where to focus on.

  6. Mindfulness training increases cooperative decision making in economic exchanges: Evidence from fMRI.

    Science.gov (United States)

    Kirk, Ulrich; Gu, Xiaosi; Sharp, Carla; Hula, Andreas; Fonagy, Peter; Montague, P Read

    2016-09-01

    Emotions have been shown to exert influences on decision making during economic exchanges. Here we investigate the underlying neural mechanisms of a training regimen which is hypothesized to promote emotional awareness, specifically mindfulness training (MT). We test the hypothesis that MT increases cooperative economic decision making using fMRI in a randomized longitudinal design involving 8weeks of either MT or active control training (CT). We find that MT results in an increased willingness to cooperate indexed by higher acceptance rates to unfair monetary offers in the Ultimatum Game. While controlling for acceptance rates of monetary offers between intervention groups, subjects in the MT and CT groups show differential brain activation patterns. Specifically, a subset of more cooperative MT subjects displays increased activation in the septal region, an area linked to social attachment, which may drive the increased willingness to express cooperative behavior in the MT cohort. Furthermore, MT resulted in attenuated activity in anterior insula compared with the CT group in response to unfair monetary offers post-training, which may suggest that MT enables greater ability to effectively regulate the anterior insula and thereby promotes social cooperation. Finally, functional connectivity analyses show a coupling between the septal region and posterior insula in the MT group, suggesting an integration of interoceptive inputs. Together, these results highlight that MT may be employed in contexts where emotional regulation is required to promote social cooperation. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. Corticosterone rapidly increases thorns of CA3 neurons via synaptic/extranuclear glucocorticoid receptor in rat hippocampus

    Directory of Open Access Journals (Sweden)

    Miyuki eYoshiya

    2013-11-01

    Full Text Available Modulation of synapses under acute stress is attracting much attention. Exposure to acute stress induces corticosterone (CORT secretion from the adrenal cortex, resulting in rapid increase of CORT levels in plasma and the hippocampus. We tried to test whether rapid CORT effects involve activation of essential kinases as non-genomic processes.We demonstrated rapid effects (~ 1 h of CORT on the density of thorns, by imaging Lucifer Yellow-injected neurons in adult male rat hippocampal slices. Thorns of thorny excrescences of CA3 hippocampal neurons are post-synaptic regions whose presynaptic partners are mossy fiber terminals. The application of CORT at 100, 500 and 1000 nM induced a rapid increase in the density of thorns in the stratum lucidum of CA3 pyramidal neurons. Co-administration of RU486, an antagonist of glucocorticoid receptor (GR, abolished the effect of CORT. Blocking a single kinase, including MAPK, PKA or PKC, suppressed CORT-induced enhancement of thorn-genesis. On the other hand, GSK-3β was not involved in the signaling of thorn-genesis. Blocking AMPA receptors suppressed the CORT effect. Expression of CA3 synaptic/extranuclear GR was demonstrated by immunogold electron microscopic analysis. From these results, stress levels of CORT (100-1000 nM might drive the rapid thorn-genesis via synaptic/extranuclear GR and multiple kinase pathways, although a role of nuclear GRs cannot be completely excluded.

  8. Problems of Development and Increase of Economic Efficiency of Sugar Beet Production

    Directory of Open Access Journals (Sweden)

    Tomashevska Olga A.

    2017-06-01

    Full Text Available The aim of the article is the studying of the trends of development and economic efficiency of sugar beet production (using the example of agricultural enterprises of Rokytne district of Kyiv region and an attempt to outline the directions for improvement of the situation in the sugar beet industry. As a result of the research, the dynamics of development and economic efficiency of sugar beet production at farms of Rokytne district of Kyiv region is analyzed, and the break-even volume of sugar beet production by agrarian enterprises of Kiev region and an individual enterprise of Rokytne district is determined. Particular attention is paid to the dynamics of profitability of sugar beet production in the period from 2011 to 2015. The main problems hindering the development of sugar beet production are identified, namely, the lack of sales channels and high production costs. Prospects for further research in this area are to increase the economic efficiency of sugar beet production and find ways to develop this sector, provided that the production is properly organized, the manufacturing process is followed, the fertilizers are properly used, the seeds are chosen correctly, advanced technologies and high-performance equipment are applied, etc.

  9. Does Rapid and Sustained Economic Growth Lead to Convergence in Health Resources: The Case of China From 1980 to 2010.

    Science.gov (United States)

    Liang, Di; Zhang, Donglan; Huang, Jiayan; Schweitzer, Stuart

    2016-01-01

    China's rapid and sustained economic growth offers an opportunity to ask whether the advantages of growth diffuse throughout an economy, or remain localized in areas where the growth has been the greatest. A critical policy area in China has been the health system, and health inequality has become an issue that has led the government to broaden national health insurance programs. This study investigates whether health system resources and performance have converged over the past 30 years across China's 31 provinces. To examine geographic variation of health system resources and performance at the provincial level, we measure the degree of sigma convergence and beta convergence in indicators of health system resources (structure), health services utilization (process), and outcome. All data are from officially published sources: the China Health Statistics Year Book and the China Statistics Year Book. Sigma convergence is found for resource indicators, whereas it is not observed for either process or outcome indicators, indicating that disparities only narrowed in health system resources. Beta convergence is found in most indicators, except for 2 procedure indicators, reflecting that provinces with poorer resources were catching up. Convergence found in this study probably reflects the mixed outcome of government input, and market forces. Thus, left alone, the equitable distribution of health care resources may not occur naturally during a period of economic growth. Governmental and societal efforts are needed to reduce geographic health variation and promote health equity. © The Author(s) 2016.

  10. The nutrition transition in amazonia: rapid economic change and its impact on growth and development in Ribeirinhos.

    Science.gov (United States)

    Piperata, Barbara A; Spence, Jennifer E; Da-Gloria, Pedro; Hubbe, Mark

    2011-09-01

    The goal of this longitudinal study was to assess the impact of economic change and increased market integration on subsistence strategies, living conditions, growth, and nutritional status of Ribeirinhos living in the rural Amazon, Brazil. Data on weight, height, skinfolds, and circumferences, as well as data on economic strategies and living conditions were collected from 469 individuals in 2002 and 429 in 2009. Of these, 204 individuals were measured on both occasions. Independent and paired t-tests were used to identify changes in nutritional status over time in the larger sample and smaller, longitudinal subsample, respectively. Multiple linear regressions were used to examine the relationship between changes in economic/living conditions and nutritional status in the longitudinal subsample. Results indicate modest improvements in linear growth (HAZ) and among male children the observed increase was related to enrollment in the Brazilian conditional cash transfer program, Bolsa Família (P = 0.03). In terms of short-term measures of nutritional status, we found a significant increase in ZTSF and a reduction in ZUMA in most age/sex groups. Among subadults, there was a negative relationship between ZUMA and access to electricity (P = 0.01) and positive relationship between ZUMA and the sale of the açaí fruit (P = 0.04). Significant changes in weight and BMI (P economic strategies and lifestyle, changes in nutritional status were modest which may be explained by increased food insecurity documented during this early stage of transition. 2010 Wiley-Liss, Inc.

  11. 78 FR 57408 - U.S. Customs and Border Protection 2013 East Coast Trade Symposium: “Increasing Economic...

    Science.gov (United States)

    2013-09-18

    ..., 2013. Maria Luisa Boyce, Senior Advisor for Private Sector Engagement, Executive Director, Office of... Protection 2013 East Coast Trade Symposium: ``Increasing Economic Competitiveness Through Global Partnership..., 2013. The theme for the 2013 East Coast Trade Symposium will be ``Increasing Economic Competitiveness...

  12. 13 CFR 123.19 - May I request an increase in the amount of an economic injury loan?

    Science.gov (United States)

    2010-01-01

    ... amount of an economic injury loan? 123.19 Section 123.19 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION DISASTER LOAN PROGRAM Overview § 123.19 May I request an increase in the amount of an economic... increase is essential for your business to continue and is based on events occurring after SBA approved...

  13. The economic benefits of malaria elimination: do they include increases in tourism?

    Science.gov (United States)

    Modrek, Sepideh; Liu, Jenny; Gosling, Roland; Feachem, Richard G A

    2012-07-28

    Policy makers have speculated that one of the economic benefits of malaria elimination includes increases in foreign direct investment, particularly tourism. This study examines the empirical relationship between the demand for travel and malaria cases in two countries with large tourism industries around the time in which they carried out malaria-elimination campaigns. In Mauritius, this analysis examines historical, yearly tourist arrivals and malaria cases from 1978-1999, accounting for the background secular trend of increasing international travel. In Dominican Republic, a country embarking upon malaria elimination, it employs a time-series analysis of the monthly, international tourist arrivals from 1998-2010 to determine whether the timing of significant deviations in tourist arrivals coincides with malaria outbreaks. While naïve relationships exist in both cases, the results show that the relationships between tourist arrivals and malaria cases are relatively weak and statistically insignificant once secular confounders are accounted for. This suggests that any economic benefits from tourism that may be derived from actively pursuing elimination in countries that have high tourism potential are likely to be small when measured at a national level. Rather, tourism benefits are likely to be experienced with greater impact in more concentrated tourist areas within countries, and future studies should seek to assess these relationships at a regional or local level.

  14. TAX COMPONENT OF FISCAL POLICY OF INCREASE COMPETITIVENESS OF NATIONAL ECONOMICS

    Directory of Open Access Journals (Sweden)

    A. Danilov

    2013-08-01

    Full Text Available The article is devoted to the problems of using fiscal levers to regulate the national economy competitiveness. What kind of tax levers should be used in order to increase the competitiveness of the national economy is justified. Taxes are the main source of fiscal revenue of the country, which depends on the inherent principles of optimizing the tax system, determined Ukraine's withdrawal from the crisis and raising the country's competitiveness. It is proposed differentiation in income tax rates, depending on whether the company is engaged in innovation and investment activity or not. Changing the rate of value added tax in a downward will reduce the revenue of the country. For enterprises that are not exporting products to decrease the amount of working capital for a certain period Fiscal policy that promotes the removal of the country's financial and economic crisis and the increasing competitiveness of the state, should be challenging. In order to implement incentive effects of taxes set forth in the tax code, we propose a linear programming model of the budget (revenue and expenditure . Building the economic and mathematical optimization model with possible actions challenging the tax factors of individual taxes and the possibilities of using the proceeds of certain taxes on certain items of expenditure budget.

  15. Economic Analysis of Cikaso Mini Hydro Power Plant as a CDM Project for Increasing IRR

    Directory of Open Access Journals (Sweden)

    Irhan Febijanto

    2013-12-01

    Full Text Available Renewable energy fueled power generations are few developed by private sector in Indonesia. High-cost investment and low electricity selling price to PT PLN as a single buyer is main barriers for private sector to involve in the development of renewable energy fueled power generations. In this project, the economic feasibility of Mini Hydro Power Plant of Cikaso with capacity of 5.3 MW, located at Sukabumi Regency, West Java province was assessed. This project utilized revenue generated from carbon market to increase the economic feasibility. Procedure to register the project to United Nation for Climate Change Convention (UNFCCC as a Clean Development Mechanism project was explained in detail. Approved Consolidation Methodology (ACM 0002 Version 12.3.0 was used to calculate grid emission factor in Jawa-Bali-Madura the grid electricity system. It was calculated that the grid emission factor is 0.833 (t-CO2/MWh, and the carbon emission reduction generated for this project is 21,982 ton/year. From the analysis result, it can be proven that the additional revenue from carbon credit could increase the project IRR from 10.28% to 13.52%.

  16. Caffeine increases the velocity of rapid eye movements in unfatigued humans.

    Science.gov (United States)

    Connell, Charlotte J W; Thompson, Benjamin; Turuwhenua, Jason; Hess, Robert F; Gant, Nicholas

    2017-08-01

    Caffeine is a widely used dietary stimulant that can reverse the effects of fatigue on cognitive, motor and oculomotor function. However, few studies have examined the effect of caffeine on the oculomotor system when homeostasis has not been disrupted by physical fatigue. This study examined the influence of a moderate dose of caffeine on oculomotor control and visual perception in participants who were not fatigued. Within a placebo-controlled crossover design, 13 healthy adults ingested caffeine (5 mg·kg -1 body mass) and were tested over 3 h. Eye movements, including saccades, smooth pursuit and optokinetic nystagmus, were measured using infrared oculography. Caffeine was associated with higher peak saccade velocities (472 ± 60° s -1 ) compared to placebo (455 ± 62° s -1 ). Quick phases of optokinetic nystagmus were also significantly faster with caffeine, whereas pursuit eye movements were unchanged. Non-oculomotor perceptual tasks (global motion and global orientation processing) were unaffected by caffeine. These results show that oculomotor control is modulated by a moderate dose of caffeine in unfatigued humans. These effects are detectable in the kinematics of rapid eye movements, whereas pursuit eye movements and visual perception are unaffected. Oculomotor functions may be sensitive to changes in central catecholamines mediated via caffeine's action as an adenosine antagonist, even when participants are not fatigued.

  17. Increasing usage of rapid diagnostics for Dengue virus detection in Pakistan

    International Nuclear Information System (INIS)

    Hasan, Z.; Razzak, S.; Farhan, M.; Rahim, M.; Islam, N.; Samreen, A.; Khan, E.

    2017-01-01

    To evaluate the trends in usage of dengue virus diagnostics in Pakistan. Methods: This retrospective study was conducted at the Aga Khan University Hospital, Karachi, and comprised data for specimens tested for dengue virus from January 2012 to December 2015. Test for dengue virus ribonucleic acid by reverse transcription polymerase chain reaction, dengue virus antigen by immunochromatic assay and for human immunoglobulin M against dengue virus by enzyme-linked immunosorbent assay were reviewed. SPSS 17 was used for data analysis. Results: Overall, 33,577 specimens tested for dengue virus. Of them, 11,995 (35.7%) were positive. among them, 1,039(8.66%) were reported in 2012; 5,791(48.28%) in 2013; 1,027(8.56%) in 2014; and 4,138(34.49%) in 2015. In 2012, 966(93%) of the positive samples were diagnosed by immunoglobulin M-based method and 73(7%) by non-structural protein-1 antigen. In 2013, 4,401(76%) samples were tested positive by immunoglobulin M, 1,332(23%) by antigen and 58(1%) by polymerase chain reaction. The trend continued in 2014, but in 2015, 2,111(51%) of all dengue positive tests were determined by antigen testing, 1,969(47.6%) by immunoglobulin M and 58(1.4%) by polymerase chain reaction. Conclusion: There was a shift in usage of direct virus identification for rapid diagnosis of dengue virus compared with host immunoglobulin M testing. (author)

  18. More rapid climate change promotes evolutionary rescue through selection for increased dispersal distance.

    Science.gov (United States)

    Boeye, Jeroen; Travis, Justin M J; Stoks, Robby; Bonte, Dries

    2013-02-01

    Species can either adapt to new conditions induced by climate change or shift their range in an attempt to track optimal environmental conditions. During current range shifts, species are simultaneously confronted with a second major anthropogenic disturbance, landscape fragmentation. Using individual-based models with a shifting climate window, we examine the effect of different rates of climate change on the evolution of dispersal distances through changes in the genetically determined dispersal kernel. Our results demonstrate that the rate of climate change is positively correlated to the evolved dispersal distances although too fast climate change causes the population to crash. When faced with realistic rates of climate change, greater dispersal distances evolve than those required for the population to keep track of the climate, thereby maximizing population size. Importantly, the greater dispersal distances that evolve when climate change is more rapid, induce evolutionary rescue by facilitating the population in crossing large gaps in the landscape. This could ensure population persistence in case of range shifting in fragmented landscapes. Furthermore, we highlight problems in using invasion speed as a proxy for potential range shifting abilities under climate change.

  19. Rapidly increasing prescribing of proton pump inhibitors in primary care despite interventions

    DEFF Research Database (Denmark)

    Haastrup, Peter; Paulsen, Maja Skov; Zwisler, Jon Eik

    2014-01-01

    Background: Guideline and reimbursement modifications have been introduced to optimize prescribing of antisecretory medication in Danish general practice. Impacts of the interventions have not been evaluated. Objectives: To analyse developments in prescribing of antisecretory medication in Denmark...... increased substantially during the past decade. Both number of users and the average individual use have increased. The prescribing of ulcerogenic drugs to the elderly has stagnated in the same time range. Reimbursement modifications and scientific guidelines do not seem to have had a substantial influence...

  20. APPLYING THE THEORY OF CONSTRAINTS TO INCREASE ECONOMIC VALUE ADDED: PART 1—THEORY

    Directory of Open Access Journals (Sweden)

    Malan Smith

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: This article, presented in two parts, explains how to apply the Theory of Constraints (TOC in a business to increase Economic Value Added (EVA. The first part deals with the theory, while the second part deals with the implementation. The goal of a business, the measurements of the goal and the priority of the measurements are discussed. The future reality of a company which implements TOC principles is shown through cause and effect to lead to an increase in EVA. The increase in EVA is caused by an increase in return on investment and a reduction in the cost of capital. The actions the company must take to increase EVA is presented.

    AFRIKAANSE OPSOMMING: Hierdie artikel, aangebied in twee dele, verduidelik hoe om die Teorie van Beperkinge (TVB in a besigheid toe te pas om Ekonomiese Toegevoegde Waarde (ETW te vermeerder. Die eerste gedeelte verduidelik die teorie, terwyl die tweede gedeelte die toepassing hanteer. Die doel van ’n besigheid, die maatstawwe van die doel en die prioriteit van die maatstawwe word bespreek. Deur middel van oorsaak en effek word gewys dat die toekomstige werklikheid van ’n besigheid wat TVB beginsels toepas lei tot ’n toename in ETW. Die toename in ETW word veroorsaak deur ’n toename in opbrengs op belegging en ’n afname in die koste van kapitaal. Die aksies wat ’n besigheid moet neem om ETW te vermeerder, word genoem.

  1. THE ECONOMIC CONSEQUENCES OF THE INCREASE OF THE WORLD OCEAN’S TEMPERATURE

    Directory of Open Access Journals (Sweden)

    Diana Perticas

    2016-12-01

    Full Text Available Environmental pollution represents one of the problems that humanity is facing right now, problems that create a series of economic, ecologic and social consequences. This paper wishes to identify by presenting concrete data, some of the negative effects that occurred as a result of the increase of pollution on global scale, for example like the rise of global temperature. Starting with the industrial revolution but especially with the increase of the population’s needs, desires, interests that occurred during the last decades, environmental pollution intensified to an extent that we could even consider alarming. A main effect which can be easily observed by each and every person without the need to perform measurements, is the climate warming which has a series of consequences, like for example: drought, natural disasters, decrease in agricultural production, fires (especially wildfires which reduce the population of wild animals, etc. So the effects of global warming are not just ecologic but also economic and social. Another aspect analyzed in this paper is the rise of the seas’ and oceans’ temperature which inevitably results in the decrease of the population of fish and aquatic animals. The melting of glaciers is another negative effect of the climate warming which is discussed in this paper, effect which is responsible for numerous floods that result from the rise of the sea levels causing numerous damages, the most affected people being those living in the vicinity of waters. During floods, phenomenon which occurs more and more often, drainage channels are overused many times not being able to handle the huge quantities of water, thus favoring the multiplication and spreading of rodents. There are evidences showing that the number of cases of diseases transmitted by rodents increases during natural disasters, which occur more and more often during the last decades.

  2. Economics.

    Science.gov (United States)

    Palley, Paul D; Parcero, Miriam E

    2016-10-01

    A review of literature in the calendar year 2015 dedicated to environmental policies and sustainable development, and economic policies. This review is divided into these sections: sustainable development, irrigation, ecosystems and water management, climate change and disaster risk management, economic growth, water supply policies, water consumption, water price regulation, and water price valuation.

  3. Rapid surface accumulation of NMDA receptors increases glutamatergic excitation during status epilepticus.

    Science.gov (United States)

    Naylor, David E; Liu, Hantao; Niquet, Jerome; Wasterlain, Claude G

    2013-06-01

    After 1h of lithium-pilocarpine status epilepticus (SE), immunocytochemical labeling of NMDA receptor NR1 subunits reveals relocation of subunits from the interior to the cell surface of dentate gyrus granule cells and CA3 pyramidal cells. Simultaneously, an increase in NMDA-miniature excitatory postsynaptic currents (mEPSC) as well as an increase in NMDA receptor-mediated tonic currents is observed in hippocampal slices after SE. Mean-variance analysis of NMDA-mEPSCs estimates that the number of functional postsynaptic NMDA receptors per synapse increases 38% during SE, and antagonism by ifenprodil suggests that an increase in the surface representation of NR2B-containing NMDA receptors is responsible for the augmentation of both the phasic and tonic excitatory currents with SE. These results provide a potential mechanism for an enhancement of glutamatergic excitation that maintains SE and may contribute to excitotoxic injury during SE. Therapies that directly antagonize NMDA receptors may be a useful therapeutic strategy during refractory SE. Copyright © 2013 Elsevier Inc. All rights reserved.

  4. Nicotine reduction as an increase in the unit price of cigarettes: a behavioral economics approach.

    Science.gov (United States)

    Smith, Tracy T; Sved, Alan F; Hatsukami, Dorothy K; Donny, Eric C

    2014-11-01

    Urgent action is needed to reduce the harm caused by smoking. Product standards that reduce the addictiveness of cigarettes are now possible both in the U.S. and in countries party to the Framework Convention on Tobacco Control. Specifically, standards that required substantially reduced nicotine content in cigarettes could enable cessation in smokers and prevent future smoking among current non-smokers. Behavioral economics uses principles from the field of microeconomics to characterize how consumption of a reinforcer changes as a function of the unit price of that reinforcer (unit price=cost/reinforcer magnitude). A nicotine reduction policy might be considered an increase in the unit price of nicotine because smokers are paying more per unit of nicotine. This perspective allows principles from behavioral economics to be applied to nicotine reduction research questions, including how nicotine consumption, smoking behavior, use of other tobacco products, and use of other drugs of abuse are likely to be affected. This paper reviews the utility of this approach and evaluates the notion that a reduction in nicotine content is equivalent to a reduction in the reinforcement value of smoking-an assumption made by the unit price approach. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. Economic costs attributable to smoking in Hong Kong in 2011: a possible increase from 1998.

    Science.gov (United States)

    Chen, Jing; McGhee, Sarah; Lam, Tai Hing

    2017-11-15

    Reduction in smoking prevalence does not necessarily reduce the costs of smoking as evidence shows in developed countries. We provide up-to-date estimates for direct and indirect costs attributable to smoking in Hong Kong in 2011 and compare with our 1998 estimates. We took a societal perspective to include lives and life years lost, health care costs and time lost from work in the costing. We followed guidelines on estimating costs of active smoking for those aged 35 years or above (35+) and costs due to SHS exposure for 35+, infants aged 12 months and under and children aged 15 and below. All costs are in US$. We estimated that 6154 deaths among 35+ in Hong Kong in 2011 were attributable to active smoking, an increase of 10% from 1998. Besides, 672 deaths were attributable to SHS exposure, i.e. 10% of the total 6826 smoking-attributable deaths. The estimate of productive life lost due to deaths from active smoking by those aged under 65 years in 2011 was $166 million, an increase of about 4% over the estimate in 1998. Our conservative estimate of the annual tobacco-related disease cost in 2011 was $716 million which accounted for 0.3% of GDP. If we added the value of attributable lives lost, the annual cost would be $4.7 billion. Despite the reduction in smoking prevalence, smoking-attributable disease still imposes a substantial economic burden on Hong Kong society. These findings support more stringent and effective tobacco control legislation, polices and measures. Current evidence shows reduction in smoking prevalence does not necessarily reduce the economic costs of smoking. Most studies in developed countries employed a societal perspective, including costs of productivity loss and indirect costs, but not all studies estimated costs associated with second-hand smoking (SHS). The present study estimated the total costs of smoking in Hong Kong including direct and indirect costs attributable to active smoking and to SHS exposure. Our study confirms the

  6. Rapid increases in training load affects markers of skeletal muscle damage and mechanical performance

    DEFF Research Database (Denmark)

    Kamandulis, Sigitas; Snieckus, Audrius; Venckunas, Tomas

    2012-01-01

    The aim of the present study was to monitor the changes in indirect markers of muscle damage during 3 weeks (nine training sessions) of stretch-shortening (drop jump) exercise with constant load alternated with steep increases in load. Physically active men (n = 9, mean age 19.1 years) performed....... Maximal jump height increased by 7.8% ± 6.3% (P training session, respectively. Gains in isometric knee extension MVC (7.9% ± 8.2%) and 100-Hz-evoked torque (9.9% ± 9.6%) (both P ... within 17 days after the end of training. The magnitude of improvement was greater after this protocol than that induced by a continuous constant progression loading pattern with small gradual load increments in each training session. These findings suggest that plyometric training using infrequent...

  7. Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production

    Science.gov (United States)

    Bailey, Andy M.; Alberti, Fabrizio; Kilaru, Sreedhar; Collins, Catherine M.; de Mattos-Shipley, Kate; Hartley, Amanda J.; Hayes, Patrick; Griffin, Alison; Lazarus, Colin M.; Cox, Russell J.; Willis, Christine L.; O'Dwyer, Karen; Spence, David W.; Foster, Gary D.

    2016-05-01

    Semi-synthetic derivatives of the tricyclic diterpene antibiotic pleuromutilin from the basidiomycete Clitopilus passeckerianus are important in combatting bacterial infections in human and veterinary medicine. These compounds belong to the only new class of antibiotics for human applications, with novel mode of action and lack of cross-resistance, representing a class with great potential. Basidiomycete fungi, being dikaryotic, are not generally amenable to strain improvement. We report identification of the seven-gene pleuromutilin gene cluster and verify that using various targeted approaches aimed at increasing antibiotic production in C. passeckerianus, no improvement in yield was achieved. The seven-gene pleuromutilin cluster was reconstructed within Aspergillus oryzae giving production of pleuromutilin in an ascomycete, with a significant increase (2106%) in production. This is the first gene cluster from a basidiomycete to be successfully expressed in an ascomycete, and paves the way for the exploitation of a metabolically rich but traditionally overlooked group of fungi.

  8. Population increase, economic growth, educational inequality, and income distribution: some recent evidence.

    Science.gov (United States)

    Ram, R

    1984-04-01

    The relationship between population increase, economic growth, education and income inequality was examined in a cross-section study based on data from 26 developing and 2 developed countries. As other studies have noted, high population growth is associated with a less equal income distribution. A 1 percentage point reduction in the rate of population growth tends to raise the income share of the poorest 80% in the less developed world by almost 5 percentage points and is associated with a 1.7 percentage point increase in the income share of the poorest 40%. The relationship between short-run income growth and equality, on the other hand, is strong and positive. Estimates suggest that a 1 percentage point increase in the short-run rate of growth of the gross domestic product (GDP) increases the income share of the bottom 80% by about 2 percentage points and that of the poorest 40% by almost 1 percentage point. Although higher mean schooling appears to be a mild equalizer, educational inequality does not appear to have an adverse effect on income distribution. Overall, these results challenge the widely held belief that there must be a growth-equity trade-off. Moreover, they suggest that the impact of educational inequality on income distribution may be different from that observed in earlier studies, implying a need for caution in using these earlier results as a basis for educational policy development.

  9. Increases in myocardial workload induced by rapid atrial pacing trigger alterations in global metabolism.

    Directory of Open Access Journals (Sweden)

    Aslan T Turer

    Full Text Available To determine whether increases in cardiac work lead to alterations in the plasma metabolome and whether such changes arise from the heart or peripheral organs.There is growing evidence that the heart influences systemic metabolism through endocrine effects and affecting pathways involved in energy homeostasis.Nineteen patients referred for cardiac catheterization were enrolled. Peripheral and selective coronary sinus (CS blood sampling was performed at serial timepoints following the initiation of pacing, and metabolite profiling was performed by liquid chromatography-mass spectrometry (LC-MS.Pacing-stress resulted in a 225% increase in the median rate·pressure product from baseline. Increased myocardial work induced significant changes in the peripheral concentration of 43 of 125 metabolites assayed, including large changes in purine [adenosine (+99%, p = 0.006, ADP (+42%, p = 0.01, AMP (+79%, p = 0.004, GDP (+69%, p = 0.003, GMP (+58%, p = 0.01, IMP (+50%, p = 0.03, xanthine (+61%, p = 0.0006], and several bile acid metabolites. The CS changes in metabolites qualitatively mirrored those in the peripheral blood in both timing and magnitude, suggesting the heart was not the major source of the metabolite release.Isolated increases in myocardial work can induce changes in the plasma metabolome, but these changes do not appear to be directly cardiac in origin. A number of these dynamic metabolites have known signaling functions. Our study provides additional evidence to a growing body of literature on metabolic 'cross-talk' between the heart and other organs.

  10. Increased insight in microbial processes in rapid sandfilters in drinking water treatment (DW BIOFILTERS)

    DEFF Research Database (Denmark)

    Albrechtsen, Hans-Jørgen; Gülay, Arda; Lee, Carson

    2012-01-01

    . The sustainability and climate friendliness are evaluated by life cycle assessment (LCA). Molecular methods based on qPCR are being developed and implemented to quantify bacteria in different functional groups, such as those responsible for nitrification. This allows for development of diagnostic tools to detect...... of increased load of e.g. ammonium, manganese and ferrous iron. This filter will also be used to validate the mathematical models build for the biological filters at full scale....

  11. Rapid responses of permafrost and vegetation to experimentally increased snow cover in sub-arctic Sweden

    International Nuclear Information System (INIS)

    Johansson, Margareta; Bosiö, Julia; Akerman, H Jonas; Jackowicz-Korczynski, Marcin; Christensen, Torben R; Callaghan, Terry V

    2013-01-01

    Increased snow depth already observed, and that predicted for the future are of critical importance to many geophysical and biological processes as well as human activities. The future characteristics of sub-arctic landscapes where permafrost is particularly vulnerable will depend on complex interactions between snow cover, vegetation and permafrost. An experimental manipulation was, therefore, set up on a lowland peat plateau with permafrost, in northernmost Sweden, to simulate projected future increases in winter precipitation and to study their effects on permafrost and vegetation. After seven years of treatment, statistically significant differences between manipulated and control plots were found in mean winter ground temperatures, which were 1.5 ° C higher in manipulated plots. During the winter, a difference in minimum temperatures of up to 9 ° C higher could be found in individual manipulated plots compared with control plots. Active layer thicknesses increased at the manipulated plots by almost 20% compared with the control plots and a mean surface subsidence of 24 cm was recorded in the manipulated plots compared to 5 cm in the control plots. The graminoid Eriophorum vaginatum has expanded in the manipulated plots and the vegetation remained green longer in the season. (letter)

  12. Socioeconomic Status Accounts for Rapidly Increasing Geographic Variation in the Incidence of Poor Fetal Growth

    Science.gov (United States)

    Ball, Stephen J.; Jacoby, Peter; Zubrick, Stephen R.

    2013-01-01

    Fetal growth is an important risk factor for infant morbidity and mortality. In turn, socioeconomic status is a key predictor of fetal growth; however, other sociodemographic factors and environmental effects may also be important. This study modelled geographic variation in poor fetal growth after accounting for socioeconomic status, with a fixed effect for socioeconomic status and a combination of spatially-correlated and spatially-uncorrelated random effects. The dataset comprised 88,246 liveborn singletons, aggregated within suburbs in Perth, Western Australia. Low socioeconomic status was strongly associated with an increased risk of poor fetal growth. An increase in geographic variation of poor fetal growth from 1999–2001 (interquartile odds ratio among suburbs = 1.20) to 2004–2006 (interquartile odds ratio = 1.40) indicated a widening risk disparity by socioeconomic status. Low levels of residual spatial patterns strengthen the case for targeting policies and practices in areas of low socioeconomic status for improved outcomes. This study indicates an alarming increase in geographic inequalities in poor fetal growth in Perth which warrants further research into the specific aspects of socioeconomic status that act as risk factors. PMID:23799513

  13. Proton Pump Inhibition Increases Rapid Eye Movement Sleep in the Rat

    Directory of Open Access Journals (Sweden)

    Munazah Fazal Qureshi

    2014-01-01

    Full Text Available Increased bodily CO2 concentration alters cellular pH as well as sleep. The proton pump, which plays an important role in the homeostatic regulation of cellular pH, therefore, may modulate sleep. We investigated the effects of the proton pump inhibitor “lansoprazole” on sleep-wakefulness. Male Wistar rats were surgically prepared for chronic polysomnographic recordings. Two different doses of lansoprazole (low: 1 mg/kg; high: 10 mg/kg were injected intraperitoneally in the same animal (n=7 and sleep-wakefulness was recorded for 6 hrs. The changes in sleep-wakefulness were compared statistically. Percent REM sleep amount in the vehicle and lansoprazole low dose groups was 9.26±1.03 and 9.09±0.54, respectively, which increased significantly in the lansoprazole high dose group by 31.75% (from vehicle and 34.21% (from low dose. Also, REM sleep episode numbers significantly increased in lansoprazole high dose group. Further, the sodium-hydrogen exchanger blocker “amiloride” (10 mg/kg; i.p. (n=5 did not alter sleep-wake architecture. Our results suggest that the proton pump plays an important role in REM sleep modulation and supports our view that REM sleep might act as a sentinel to help maintain normal CO2 level for unperturbed sleep.

  14. Rapidly increasing macroalgal cover not related to herbivorous fishes on Mesoamerican reefs

    Directory of Open Access Journals (Sweden)

    Adam Suchley

    2016-05-01

    Full Text Available Long-term phase shifts from coral to macroalgal dominated reef systems are well documented in the Caribbean. Although the impact of coral diseases, climate change and other factors is acknowledged, major herbivore loss through disease and overfishing is often assigned a primary role. However, direct evidence for the link between herbivore abundance, macroalgal and coral cover is sparse, particularly over broad spatial scales. In this study we use a database of coral reef surveys performed at 85 sites along the Mesoamerican Reef of Mexico, Belize, Guatemala and Honduras, to examine potential ecological links by tracking site trajectories over the period 2005–2014. Despite the long-term reduction of herbivory capacity reported across the Caribbean, the Mesoamerican Reef region displayed relatively low macroalgal cover at the onset of the study. Subsequently, increasing fleshy macroalgal cover was pervasive. Herbivorous fish populations were not responsible for this trend as fleshy macroalgal cover change was not correlated with initial herbivorous fish biomass or change, and the majority of sites experienced increases in macroalgae browser biomass. This contrasts the coral reef top-down herbivore control paradigm and suggests the role of external factors in making environmental conditions more favourable for algae. Increasing macroalgal cover typically suppresses ecosystem services and leads to degraded reef systems. Consequently, policy makers and local coral reef managers should reassess the focus on herbivorous fish protection and consider complementary measures such as watershed management in order to arrest this trend.

  15. Recent rapid increases in the demand for city gas in manufacturing industries and future developments

    International Nuclear Information System (INIS)

    Kusano, Shigero

    1992-01-01

    City gas companies in Japan are experiencing an expansion in demand for gas in all manufacturing industries. The reason for this is, first and foremost, external, in that the first and second oil crises and the recent Gulf War have placed the oil market in a state of flux. That is to say, supply and demand in the oil products market is unstable while the stability of city gas, which is the main raw material for LNG, is being highly appraised. Another external reason is related to a subject much in the news recently the world over - the environment. City gas is highly regarded for its minimum environmental impact. Domestic reasons for the expansion include the fact that with the increase in use of city gas in manufacturing industries, the end user is beginning to recognize the various special qualities that city gas possesses. The expansion is also due in part to the unrelenting efforts in sales by the gas producers themselves. This report focuses on the expansion in demand in city gas over the past ten years from the point of view of Tokyo Gas as a producer that has been party to the increased sales of city gas in manufacturing industries for over 10 years giving views on the reasons for the increase. Graphic reports of the actual situation of the industry at meetings such as these are rare and therefore although this is slightly different from the main theme, I would like to proceed with the debate in the hope that this will be beneficial in the expansion of future gas demand in countries all over the world

  16. Rapid increases and time-lagged declines in amphibian occupancy after wildfire.

    Science.gov (United States)

    Hossack, Blake R; Lowe, Winsor H; Corn, Paul Stephen

    2013-02-01

    Climate change is expected to increase the frequency and severity of drought and wildfire. Aquatic and moisture-sensitive species, such as amphibians, may be particularly vulnerable to these modified disturbance regimes because large wildfires often occur during extended droughts and thus may compound environmental threats. However, understanding of the effects of wildfires on amphibians in forests with long fire-return intervals is limited. Numerous stand-replacing wildfires have occurred since 1988 in Glacier National Park (Montana, U.S.A.), where we have conducted long-term monitoring of amphibians. We measured responses of 3 amphibian species to fires of different sizes, severity, and age in a small geographic area with uniform management. We used data from wetlands associated with 6 wildfires that burned between 1988 and 2003 to evaluate whether burn extent and severity and interactions between wildfire and wetland isolation affected the distribution of breeding populations. We measured responses with models that accounted for imperfect detection to estimate occupancy during prefire (0-4 years) and different postfire recovery periods. For the long-toed salamander (Ambystoma macrodactylum) and Columbia spotted frog (Rana luteiventris), occupancy was not affected for 6 years after wildfire. But 7-21 years after wildfire, occupancy for both species decreased ≥ 25% in areas where >50% of the forest within 500 m of wetlands burned. In contrast, occupancy of the boreal toad (Anaxyrus boreas) tripled in the 3 years after low-elevation forests burned. This increase in occupancy was followed by a gradual decline. Our results show that accounting for magnitude of change and time lags is critical to understanding population dynamics of amphibians after large disturbances. Our results also inform understanding of the potential threat of increases in wildfire frequency or severity to amphibians in the region. ©2012 Society for Conservation Biology.

  17. Economic and environmental effects of providing increased amounts of solid feed to veal calves.

    Science.gov (United States)

    Mollenhorst, H; Berentsen, P B M; Berends, H; Gerrits, W J J; de Boer, I J M

    2016-03-01

    Traditionally, veal calves receive most of their nutrients from milk replacer (MR). Nowadays, however, solid feed (SF; i.e., concentrates and roughages) increasingly substitutes for MR. Studies have shown that providing SF reduces different types of nonnutritive oral behaviors. The objective of this study was to assess the economic and environmental effects of substituting SF for MR in veal calf diets. With respect to environmental effects, we considered the emission of greenhouse gases and land occupation. Substitution rates were based on an experiment in which 160 calves were provided 2 mixtures of SF at 4 levels of dry matter (DM) intake. Mixtures of SF contained either 80% concentrates, 10% corn silage, and 10% straw on DM basis (C80) or 50% concentrates, 25% corn silage, and 25% straw (C50). The 4 levels of SF during the last 17 wk of the fattening period were 20, 100, 180, and 260 kg of DM SF. Additionally, provision of MR was adjusted to achieve equal rates of carcass gain. Substitution rates, representing the SF equivalent needed to substitute for 1 kg of DM MR, were 1.43 kg of DM for C80 and 1.61 kg of DM for C50. Economic effects were assessed based on prices and substitution rates of SF for MR and the possible penalty for carcass color. Environmental effects were assessed based on effects related to the production of feed ingredients, substitution rates, and changes in enteric methane emission and energy use for feed preparation. Costs of feeding SF needed to substitute for 1 kg of DM MR were €0.68 lower for C80 and €0.71 lower for C50, compared with the costs of feeding 1 kg of DM MR. When carcass color scores became too high, however, lower feeding costs were offset by lower revenues from meat. Emissions of greenhouse gases were hardly affected when SF intake was increased. In general, increased enteric methane emission were offset by lower emissions from feed production and energy use. Land occupation increased when intake of SF was increased

  18. Rapid Increase in Scrub Typhus Incidence in Mainland China, 2006-2014.

    Science.gov (United States)

    Wu, Yi-Cheng; Qian, Quan; Magalhaes, Ricardo J Soares; Han, Zhi-Hai; Haque, Ubydul; Weppelmann, Thomas A; Hu, Wen-Biao; Liu, Yun-Xi; Sun, Yan-Song; Zhang, Wen-Yi; Li, Shen-Long

    2016-03-01

    Scrub typhus is a vector-borne disease, which has recently reemerged in China. In this study, we describe the distribution and incidence of scrub typhus cases in China from 2006 to 2014 and quantify differences in scrub typhus cases with respect to sex, age, and occupation. The results of our study indicate that the annual incidence of scrub typhus has increased during the study period. The number of cases peaked in 2014, which was 12.8 times greater than the number of cases reported in 2006. Most (77.97%) of the cases were reported in five provinces (Guangdong, Yunnan, Anhui, Fujian, and Shandong). Our study also demonstrates that the incidence rate of scrub typhus was significantly higher in females compared to males (P scrub typhus incidence, but also document an expansion in the geographic distribution throughout the country. © The American Society of Tropical Medicine and Hygiene.

  19. Symptoms and Mucosal Changes Stable During Rapid Increase of Pediatric Celiac Disease in Norway.

    Science.gov (United States)

    Beitnes, Ann-Christin R; Vikskjold, Florin B; Jóhannesdóttir, Gróa B; Perminow, Gøri; Olbjørn, Christine; Andersen, Solveig N; Bentsen, Beint S; Rugtveit, Jarle; Størdal, Ketil

    2017-04-01

    We aimed to study whether the incidence of pediatric celiac disease (CD) in South-Eastern Norway changed from 2000 to 2010. We also examined whether there was a change in symptoms and histopathological morphology in the duodenal biopsies during the same period. In 3 hospitals in South-Eastern Norway, records from pediatric patients (0-14.9 years) diagnosed with CD during two 3-year periods (2000-2002 and 2008-2010) were reviewed. Only cases with a duodenal biopsy diagnosis of CD classified as Marsh grade 2 and 3a-c were included. Frequencies of symptoms, anthropometric data, and laboratory results were compared, in addition to re-examinations of histological sections from one of the hospitals. A total of 400 cases were diagnosed with a female to male ratio of 1.5:1. The incidence rate for 2000 to 2002 was 15.9 cases per 100,000 person-years (95% confidence interval 12.8-19.4), compared with 45.5 cases per 100,000 person-years during 2008 to 2010 (95% confidence interval 40.5-50.9), P symptoms and the distribution of histopathological changes were similar in the 2 periods, whereas weight z scores and hemoglobin levels were significantly lower in the first period. We found a 3-fold increase in the incidence rate for CD in the Norwegian pediatric population during the decade 2000 to 2010. Slightly higher weight and hemoglobin levels at diagnosis in the latter period may be due to improved CD awareness. Unaltered relative frequencies of symptoms and histopathological changes in the gut, however, suggest a true increase of CD in Norwegian children.

  20. Energy system, electricity market and economic studies on increasing nuclear power capacity

    International Nuclear Information System (INIS)

    Forsstrom, J.; Pursiheimo, E.; Kekkonen, V.; Honkatukia, J.

    2010-04-01

    Objective of this research project is to examine effects of addition of nuclear capacity from three different angles by using energy system, electricity market and economic analysis. In each area the analysis is based on computational methods. Finland is a member of Nordic electricity market which is further connected to networks of Continental Europe and Russia. Due to the foreign connections Finland has been able to import inexpensive electricity from its neighboring countries and this state is expected to continue. Addition of nuclear capacity lowers electricity import demand, affects level of electricity price decreasingly and decreases shortfall of installed production capacity. Substantial additions of nuclear power capacity and generous import supply have disadvantageous effect on profitability of combined heat and power production. The development of import possibilities depends on progression of difficult-to-estimate balance between electricity consumption and production in the neighboring countries. Investments on nuclear power increase national product during the construction phase. Growth of employment is also rather significant, especially during the construction phase. In the long term permanent jobs will be created too. Increase of employment is held back by increasing real wages, but it is though evident that consumer purchasing power is improved due to these nuclear power developments. (orig.)

  1. Economism

    Directory of Open Access Journals (Sweden)

    P. Simons

    2010-07-01

    Full Text Available Modern society is characterised not only by a fascination with scientific technology as a means of solving all problems, especially those that stand in the way of material progress (technicism, but also by an obsessive interest in everything that has to do with money (economism or mammonism. The article discusses the relationship between technicism and economism, on the basis of their relationship to utilitarian thinking: the quest for the greatest happiness for the greatest number of people. Recent major studies of neo-liberalism (seen as an intensification of utilitarianism by Laval and Dardot are used as reference to the development of utilitarianism. It is suggested that the western view of the world, as expressed in economism and technicism, with a utilitarian ethics, features three absolutisations: those of theoretical thinking, technology and economics. In a second part, the article draws on the framework of reformational philosophy to suggest an approach that, in principle, is not marred by such absolutisations.

  2. Synthetic polymers in the marine environment: a rapidly increasing, long-term threat.

    Science.gov (United States)

    Moore, Charles James

    2008-10-01

    Synthetic polymers, commonly known as plastics, have been entering the marine environment in quantities paralleling their level of production over the last half century. However, in the last two decades of the 20th Century, the deposition rate accelerated past the rate of production, and plastics are now one of the most common and persistent pollutants in ocean waters and beaches worldwide. Thirty years ago the prevailing attitude of the plastic industry was that "plastic litter is a very small proportion of all litter and causes no harm to the environment except as an eyesore" [Derraik, J.G.B., 2002. The pollution of the marine environment by plastic debris: a review. Mar. Pollut. Bull. 44(9), 842-852]. Between 1960 and 2000, the world production of plastic resins increased 25-fold, while recovery of the material remained below 5%. Between 1970 and 2003, plastics became the fastest growing segment of the US municipal waste stream, increasing nine-fold, and marine litter is now 60-80% plastic, reaching 90-95% in some areas. While undoubtedly still an eyesore, plastic debris today is having significant harmful effects on marine biota. Albatross, fulmars, shearwaters and petrels mistake floating plastics for food, and many individuals of these species are affected; in fact, 44% of all seabird species are known to ingest plastic. Sea turtles ingest plastic bags, fishing line and other plastics, as do 26 species of cetaceans. In all, 267 species of marine organisms worldwide are known to have been affected by plastic debris, a number that will increase as smaller organisms are assessed. The number of fish, birds, and mammals that succumb each year to derelict fishing nets and lines in which they become entangled cannot be reliably known; but estimates are in the millions. We divide marine plastic debris into two categories: macro, >5 mm and micro, plastic micro-debris by filter feeders at the base of the food web is known to occur, but has not been quantified

  3. Increased common carotid artery wall thickness is associated with rapid progression of asymptomatic carotid stenosis.

    Science.gov (United States)

    Diomedi, Marina; Scacciatelli, Daria; Misaggi, Giulia; Balestrini, Simona; Balucani, Clotilde; Sallustio, Fabrizio; Di Legge, Silvia; Stanzione, Paolo; Silvestrini, Mauro

    2014-01-01

    This study aimed to identify clinical and ultrasound imaging predictors of progression of carotid luminal narrowing in subjects with asymptomatic moderate internal carotid artery (ICA) stenosis. A total of 571 subjects with asymptomatic moderate (50-69%) ICA stenoses were enrolled. They underwent ultrasound examination at baseline and after 12 months. Demographics, vascular risk factors, medications, plaque characteristics (surface and echogenicity) and common carotid intima-media thickness (IMT) were collected. At the follow-up examination, any change of ICA stenosis was graded in three categories (i) ≥70% to near occlusion, (ii) near occlusion, and (iii) occlusion. Progression of stenosis was defined as an increase in the stenosis degree by at least one category from baseline to follow-up. At 12 months, progression occurred in 142 subjects (prevalence rate 25%). At the multivariable logistic model, pathological IMT values (considered as binary variable: normal: ≤1 mm vs. pathologic: >1 mm) significantly predicted the risk for plaque progression after adjusting the model for possible confounders (OR 2.28, 95% CI 1.18-4.43, P = .014, multivariable logistic model). Our results confirm the role of carotid wall thickening as a marker of atherosclerosis. Carotid IMT measurement should be considered to implement risk stratification in patients with asymptomatic carotid disease.

  4. Rapid temperature increase near the anode and cathode in the afterglow of a pulsed positive streamer discharge

    Science.gov (United States)

    Ono, Ryo

    2018-06-01

    The spatiotemporal evolution of the temperature in the afterglow of point-to-plane, pulsed positive streamer discharge was measured near the anode tip and cathode surface using laser-induced predissociation fluorescence of OH radicals. The temperature exhibited a rapid increase and displayed a steep spatial gradient after a discharge pulse. The rate of temperature rise reached 84 K μs‑1 at mm, where z represents the distance from the anode tip. The temperature rise was much faster than in the middle of the gap; it was only 2.8 K μs‑1 at mm. The temperature reached 1700 K near the anode tip at s and 1500 K near the cathode surface at s, where t represents the postdischarge time. The spatial gradient reached 1280 K mm‑1 near the anode tip at s. The mechanism responsible for the rapid temperature increase was discussed, including rapid heating of the gas in the early postdischarge phase (s), and vibration-to-translation energy transfer in the later postdischarge phase (s). The high temperatures near the anode tip and cathode surface are particularly important for the ignition of combustible mixtures and for surface treatments, including solid-surface treatments, water treatments, and plasma medicine using pulsed streamer discharges.

  5. Protein and glucogenic precursor supplementation: a nutritional strategy to increase reproductive and economic output.

    Science.gov (United States)

    Mulliniks, J T; Cox, S H; Kemp, M E; Endecott, R L; Waterman, R C; Vanleeuwen, D M; Torell, L A; Petersen, M K

    2011-10-01

    Reproductive performance in young beef cows is often compromised due to a mismatch of physiological demands and suboptimal environmental conditions. Studies conducted at the Corona Range and Livestock Research Center from 2000 to 2007 evaluated 3 postpartum supplement strategies that varied in the amount of glucogenic potential (GP) supplied. Reproductive variables, milk production, and serum metabolites were used to assess supplement effectiveness and economics associated with 2- and 3-yr-old beef cows (n = 379) grazing native range. Supplements were individually fed twice/week at 1,135 g/d (2003 to 2004) or 908 g/d (all other years) and provided 1) 327 g of CP, 109 to 118 g of RUP (CON); 2) 327 to 341 g of CP, 142 to 157 g of RUP (RUP); or 3) 327 g of CP, 151 to 173 g of RUP + 40 to 100 g of propionate salt (PS; RUP+PS). Ultimately, total GP for CON, RUP, and RUP+PS was 44 to 47, 57 to 70, and 93 to 141 g, respectively. Blood samples were collected once/week (2000) or twice/week (2001 to 2007) for progesterone analysis to estimate days to resumption of estrus. Cows were exposed to bulls for 60 d or less, and pregnancy was confirmed by rectal palpation at weaning. Days to resumption of estrus after calving decreased linearly (P = 0.02), resulting in an increased pregnancy rate (P = 0.03) with increasing GP. Milk production exhibited a quadratic (P = 0.04) response to increasing GP, with cows fed RUP producing the most amount of milk. However, a linear decrease (P = 0.07) in days from BW nadir to estrus was found with increasing GP. Total kilograms of calf weaned per cow exposed for the supplemental year and subsequent year was increased linearly (P = 0.07) with increased GP. The improvement in pregnancy rate by supplementing RUP+PS resulted in an increase in total revenue of 18% compared with CON-fed cows and 9.5% compared with RUP-fed cows in the subsequent year after supplementation. These data suggest feeding young cows additional GP in the form of PS allows

  6. Rapidly increasing body mass index among children, adolescents and young adults in a transitioning population, South Africa, 2008-15.

    Science.gov (United States)

    Sartorius, B; Sartorius, K; Taylor, M; Aagaard-Hansen, J; Dukhi, N; Day, C; Ndlovu, N; Slotow, R; Hofman, K

    2017-12-14

    There is a global epidemic of overweight and obesity; however, this rate of increase is even greater in some low- and middle-income countries (LMIC). South Africa (SA) is undergoing rapid socioeconomic and demographic changes that have triggered a rapid nutrition transition. The paper focuses on the recent rate of change of body mass index (BMI) among children, adolescents and young adults, further stratified by key sociodemographic factors. We analysed mean BMI of 28 247 individuals (including children) from 7301 households by age and year, from anthropometric data from four national cross-sectional (repeated panel) surveys using non-linear fitted curves and associated 95% confidence intervals. From 2008 to 2015, there was rapid rise in mean BMI in the 6-25 age band, with the highest risk (3-4+ BMI unit increase) among children aged 8-10 years. The increase was largely among females in urban areas and of middle-high socioeconomic standing. Prominent gains were also observed in certain rural areas, with extensive geographical heterogeneity across the country. We have demonstrated a major deviation from the current understanding of patterns of BMI increase, with a rate of increase substantially greater in the developing world context compared with the global pattern. This population-wide effect will have major consequences for national development as the epidemic of related non-communicable disease unfolds, and will overtax the national health care budget. Our refined understanding highlights that risks are further compounded for certain groups/places, and emphasizes that urgent geographical and population-targeted interventions are necessary. These interventions could include a sugar tax, clearer food labelling, revised school feeding programmes and mandatory bans on unhealthy food marketing to children.The scenario unfolding in South Africa will likely be followed in other LMICs. © The Author 2017. Published by Oxford University Press on behalf of the

  7. Mutual Payments in Increase of the Level of Economic Security of Energy Generating Enterprises

    Directory of Open Access Journals (Sweden)

    Ruzhytskyi Andrіy V

    2013-12-01

    Full Text Available The article presents main approaches to the essence of the economic security of an enterprise notion, namely, approach of counter-action to threats, approach of successful market activity and approach of achievement of certain development goals; it identifies the role of economic security of energy generating enterprises in economic security of other subjects and the country in general; it offers definition of the economic security of an enterprise notion as a complex characteristic of the state of the enterprise that reflects the level of the enterprise possibility to ensure functioning and development; it marks out functional components of economic security, which are connected with mutual payments, namely, financial, personnel, technical and technological, political and legal, informational and interface ones; it presents connection of mutual payments with the level of financial component of economic security of enterprises, which envisages financial flow from or to the enterprise for changing the obligation status or its quantitative characteristics.

  8. Environmental and economic impacts of livestock productivity increase in sub-Saharan Africa.

    Science.gov (United States)

    Cardoso, Luis Alfaro

    2012-12-01

    Livestock production in sub-Saharan Africa (SSA) is not matching the annual 2.5 % growth of its population. Regional per capita meat and milk production corresponds, respectively, to about 13 and 8 % of developed countries indicators. Livestock performances in this region have decreased within the last 30 years. In fact, SSA, with a 12 % bovine extraction rate against a world average of 21 %, includes about 16 % of world cattle, only producing 6 and 2.6 % of global meat and milk, respectively. These low performances have economic and environmental consequences reflecting the necessity for upgrading livestock managing skills in the region. This effort includes various components such as sanitary prophylaxis, reproduction, nutrition, and in particular, substantial increase in livestock yield for human consumption. This will allow for an improved animal and pasture management and soil preservation, enhancing meat production and decreasing methane and nitrogen emissions from enteric fermentation and manure processing. These environmental gains due to increased livestock off-take rates can represent relevant credits in the global Environmental Carbon Market under the United Nations Framework Convention on Climate Change Kyoto protocol. These credits can be used for investments in livestock essential services and marketing facilities leading to improved productivity.

  9. Modeling The Economic And Health Impact Of Increasing Children's Physical Activity In The United States.

    Science.gov (United States)

    Lee, Bruce Y; Adam, Atif; Zenkov, Eli; Hertenstein, Daniel; Ferguson, Marie C; Wang, Peggy I; Wong, Michelle S; Wedlock, Patrick; Nyathi, Sindiso; Gittelsohn, Joel; Falah-Fini, Saeideh; Bartsch, Sarah M; Cheskin, Lawrence J; Brown, Shawn T

    2017-05-01

    Increasing physical activity among children is a potentially important public health intervention. Quantifying the economic and health effects of the intervention would help decision makers understand its impact and priority. Using a computational simulation model that we developed to represent all US children ages 8-11 years, we estimated that maintaining the current physical activity levels (only 31.9 percent of children get twenty-five minutes of high-calorie-burning physical activity three times a week) would result each year in a net present value of $1.1 trillion in direct medical costs and $1.7 trillion in lost productivity over the course of their lifetimes. If 50 percent of children would exercise, the number of obese and overweight youth would decrease by 4.18 percent, averting $8.1 billion in direct medical costs and $13.8 billion in lost productivity. Increasing the proportion of children who exercised to 75 percent would avert $16.6 billion and $23.6 billion, respectively. Project HOPE—The People-to-People Health Foundation, Inc.

  10. Phylogenomics of a rapid radiation: is chromosomal evolution linked to increased diversification in north american spiny lizards (Genus Sceloporus)?

    Science.gov (United States)

    Leaché, Adam D; Banbury, Barbara L; Linkem, Charles W; de Oca, Adrián Nieto-Montes

    2016-03-22

    Resolving the short phylogenetic branches that result from rapid evolutionary diversification often requires large numbers of loci. We collected targeted sequence capture data from 585 nuclear loci (541 ultraconserved elements and 44 protein-coding genes) to estimate the phylogenetic relationships among iguanian lizards in the North American genus Sceloporus. We tested for diversification rate shifts to determine if rapid radiation in the genus is correlated with chromosomal evolution. The phylogenomic trees that we obtained for Sceloporus using concatenation and coalescent-based species tree inference provide strong support for the monophyly and interrelationships among nearly all major groups. The diversification analysis supported one rate shift on the Sceloporus phylogeny approximately 20-25 million years ago that is associated with the doubling of the speciation rate from 0.06 species/million years (Ma) to 0.15 species/Ma. The posterior probability for this rate shift occurring on the branch leading to the Sceloporus species groups exhibiting increased chromosomal diversity is high (posterior probability = 0.997). Despite high levels of gene tree discordance, we were able to estimate a phylogenomic tree for Sceloporus that solves some of the taxonomic problems caused by previous analyses of fewer loci. The taxonomic changes that we propose using this new phylogenomic tree help clarify the number and composition of the major species groups in the genus. Our study provides new evidence for a putative link between chromosomal evolution and the rapid divergence and radiation of Sceloporus across North America.

  11. Possible causes of the recent rapid increase in the radial increment of silver fir in the Western Carpathians

    International Nuclear Information System (INIS)

    Bošeľa, Michal; Petráš, Rudolf; Sitková, Zuzana; Priwitzer, Tibor; Pajtík, Jozef; Hlavatá, Helena; Sedmák, Róbert; Tobin, Brian

    2014-01-01

    Silver fir is one of the most productive and ecologically valuable native European tree species, however, it has been experiencing decline which has periodically occurred over its natural range. This paper aims to investigate the recent climate–growth relationships of silver fir (Abies alba Mill.) and its temporal change along the course of its life. Long-term tree-ring databases, as well as records on climate, atmospheric SO 2 , NO 3 and acid concentrations from four different regions in the Western Carpathians were used. The results provide clear evidence of significant increase of silver fir's radial increment over the entire Western Carpathian area since 1970–1980. The results indicated that the most probable factors behind the rapid recovery of tree radial increment were reductions in emissions of NO 3 and SO 2 , alongside a significant increase in mean June, July and April temperatures. Highlights: • Silver fir radial growth was mostly related to mean month late winter temperatures. • Silver fir growth also responded to summer, especially July temperatures. • Strength of the climate–growth response has gradually increased since 1960–1980. • SO 2 , NO 3 , and recent climate change as major factor of the rapid radial growth recovery. -- Reductions of SO 2 and NO 3 emission along with climate change are the major causes of the recent recovery of Silver fir radial growth

  12. Manipulating the antioxidant capacity of halophytes to increase their cultural and economic value through saline cultivation.

    Science.gov (United States)

    Boestfleisch, Christian; Wagenseil, Niko B; Buhmann, Anne K; Seal, Charlotte E; Wade, Ellie Merrett; Muscolo, Adele; Papenbrock, Jutta

    2014-08-13

    Halophytes, salt-tolerant plants, are a source of valuable secondary metabolites with potential economic value. The steady-state pools of many stress-related metabolites are already enhanced in halophytes when compared with glycophytes, but growth under conditions away from the optimum can induce stress and consequently result in changes to secondary metabolites such as antioxidants. However, direct evidence for increasing the concentration of valuable secondary metabolites as a consequence of altering the salinity of the growing environment still remains equivocal. To address this, we analysed a range of metabolites with antioxidant capacity (including total phenols, flavonoids, ascorbate, reduced/oxidized glutathione and reactive oxygen species scavenging enzymes) in seedlings and plants from different families (Amaranthaceae, Brassicaceae, Plantaginaceae and Rhizophoraceae) and habitats grown under different salt concentrations. We show that it is possible to manipulate the antioxidant capacity of plants and seedlings by altering the saline growing environment, the length of time under saline cultivation and the developmental stage. Among the species studied, the halophytes Tripolium pannonicum, Plantago coronopus, Lepidium latifolium and Salicornia europaea demonstrated the most potential as functional foods or nutraceuticals. Published by Oxford University Press on behalf of the Annals of Botany Company.

  13. Stochasticity in economic losses increases the value of reputation in indirect reciprocity.

    Science.gov (United States)

    dos Santos, Miguel; Placì, Sarah; Wedekind, Claus

    2015-12-14

    Recent theory predicts harsh and stochastic conditions to generally promote the evolution of cooperation. Here, we test experimentally whether stochasticity in economic losses also affects the value of reputation in indirect reciprocity, a type of cooperation that is very typical for humans. We used a repeated helping game with observers. One subject (the "Unlucky") lost some money, another one (the "Passer-by") could reduce this loss by accepting a cost to herself, thereby building up a reputation that could be used by others in later interactions. The losses were either stable or stochastic, but the average loss over time and the average efficiency gains of helping were kept constant in both treatments. We found that players with a reputation of being generous were generally more likely to receive help by others, such that investing into a good reputation generated long-term benefits that compensated for the immediate costs of helping. Helping frequencies were similar in both treatments, but players with a reputation to be selfish lost more resources under stochastic conditions. Hence, returns on investment were steeper when losses varied than when they did not. We conclude that this type of stochasticity increases the value of reputation in indirect reciprocity.

  14. Rapid Bolus Administration Does not Increase The Extravasation Rate of Albumin: A Randomized Controlled Trial in The Endotoxemic Pig.

    Science.gov (United States)

    von Seth, Magnus; Lipcsey, Miklós; Engström, Peter; Larsson, Anders; Hillered, Lars; Maripuu, Enn; Widström, Charles; Sjölin, Jan

    2017-04-01

    Some experimental data suggest that rapid bolus administration of albumin causes less plasma-expanding effects than slow, continuous infusion. To determine whether rapid bolus administration, in comparison with slow infusion, results in greater extravasation of albumin in experimental septic shock we performed a randomized controlled trial with 32 endotoxemic pigs. The animals were monitored and ventilated with standard intensive care equipment and given 10 mL × kg 5% albumin labeled with Technetium-99m, either as a rapid 15-min bolus (Bolus group, n = 16) or as a 2-h infusion (Infusion group, n = 16). Radioactivity was monitored in plasma, extracellular microdialysate, and urine for 6 h. Physiological parameters were monitored hourly. Radioactivity in the liver, spleen, kidney, and lung was analyzed post mortem.The plasma area under the curve activity0-6 h was 4.4 ± 0.9 × 10 in the Bolus group and 4.4 ± 1.1 × 10 counts × min × mL × h in the Infusion group. Blood hemoglobin levels increased in both groups, suggesting severe capillary leakage. Yet, there were no group differences in albumin radioactivity in plasma, muscle tissue, urine, or in the post-mortem analysis of the organs. Following albumin administration, circulatory and respiratory parameters were similar in the two groups.In conclusion, the present results suggest that albumin might be given as a bolus without leading to increased extravasation of albumin, in contrast to previous animal experiments in rodents.

  15. Alternative long term strategies for sustainable development: Rapidly increasing electricity consumption in Asian countries and future role of nuclear energy

    International Nuclear Information System (INIS)

    Sagawa, N.

    1997-01-01

    Many people in the world express the concern that global warming will become an increasingly serious problem. A rapid increase in population and demand for energy in the Asian region must be discussed in this context. Despite the forecast of an increase in demand for energy, the Asian region is short of oil and natural gas resources. In addition, only less energy can be supplied by renewable energy sources in the Asian region than in the other regions because of high population density. Nuclear energy is an important energy resource for fulfilling the future increasing energy demand in the Asian region and for contributing to the suppression of carbon dioxide emissions. In the Asian region alone, however, we cannot rely limitlessly on LWR which does not use plutonium. According to a scenario analysis, the total capacity of nuclear power plants in the Asian region would reach large scale and the cumulative amount of demand for natural uranium will increase to about 5 million tons in the Asian region alone. Just the nuclear power plants of this scale in Asia alone will rapidly consume the world's cheap natural uranium resources if we rely only on natural uranium. In the Asian region, few countries have embarked on nuclear power generation and the capacity of equipment is still small. Currently, however, many plans for nuclear power generation are being designed. Many Asian countries obviously consider nuclear power generation as a valid option. Many potential policies must be examined in the light of future uncertainty. In the future, both renewable energy and nuclear energy must be resorted to. When nuclear energy is utilized, the use of plutonium and FBR in the Asian region must be taken into account in order to attain continual growth and development. (author)

  16. The population in China’s earthquake-prone areas has increased by over 32 million along with rapid urbanization

    Science.gov (United States)

    He, Chunyang; Huang, Qingxu; Dou, Yinyin; Tu, Wei; Liu, Jifu

    2016-07-01

    Accurate assessments of the population exposed to seismic hazard are crucial in seismic risk mapping. Recent rapid urbanization in China has resulted in substantial changes in the size and structure of the population exposed to seismic hazard. Using the latest population census data and seismic maps, this work investigated spatiotemporal changes in the exposure of the population in the most seismically hazardous areas (MSHAs) in China from 1990 to 2010. In the context of rapid urbanization and massive rural-to-urban migration, nearly one-tenth of the Chinese population in 2010 lived in MSHAs. From 1990 to 2010, the MSHA population increased by 32.53 million at a significantly higher rate of change (33.6%) than the national average rate (17.7%). The elderly population in MSHAs increased by 81.4%, which is much higher than the group’s national growth rate of 58.9%. Greater attention should be paid to the demographic changes in earthquake-prone areas in China.

  17. Economic cost of increased somatic cell count in South African dairy ...

    African Journals Online (AJOL)

    cuthbert

    2014-06-24

    Jun 24, 2014 ... Relative economic values, standardized to the value of protein, were ... as somatic cell count (SCC), is the most widely used measure of raw milk quality. .... Milk (l). Fat (kg). Protein (kg). Calving interval (days). Live weight (kg).

  18. Economic benefits of productivity increases through truck-to-rail mode shift in freight transport.

    Science.gov (United States)

    2016-01-29

    Although the study of economic benefits of improving (or not improving) the efficiency of freight movement has been recognized as one of the critical research topic by the decision makers and researchers alike, there remains a dearth of transparent a...

  19. Changes in Indirect Markers of Muscle Damage and Tendons After Daily Drop Jumping Exercise with Rapid Load Increase

    Directory of Open Access Journals (Sweden)

    Vidas Paleckis, Mantas Mickevičius, Audrius Snieckus, Vytautas Streckis, Mati Pääsuke, Saulius Rutkauskas, Rasa Steponavičiūtė, Albertas Skurvydas, Sigitas Kamandulis

    2015-12-01

    Full Text Available The aim of this study was to assess changes in indirect markers of muscle damage and type I collagen degradation, as well as, patellar and Achilles tendon morphological differences during nine daily drop-jumps sessions with constant load alternated with rapid increases in load to test the hypothesis that frequent drop-jump training results in negative muscular and tendon adaptation. Young men (n = 9 performed daily drop jump workouts with progression every 3 days in terms of number of jumps, platform height and squat amplitude. Voluntary and electrically evoked knee extensor torque, muscle soreness, blood plasma creatine kinase (CK activity and carboxyterminal cross-linked telopeptide (ICTP, patellar and Achilles tendon thickness and cross-sectional area (CSA were assessed at different time points during the training period and again on days 1, 3, 10 and 17 after the training. The findings were as follows: (1 steady decline in maximal muscle strength with major recovery within 24 hours after the first six daily training sessions; (2 larger decline in electrically induced muscle torque and prolonged recovery during last three training sessions; (3 increase in patellar and Achilles tendons CSA without change in thickness towards the end of training period; (4 increase in jump height but not in muscle strength after whole training period. Our findings suggest that frequent drop-jump sessions with constant load alternated with rapid increases in load do not induce severe muscle damage or major changes in tendons, nonetheless, this type of loading is not advisable for muscle strength improvement.

  20. Applying Psychology to Economic Policy Design: Using Incentive Preserving Rebates to Increase Acceptance of Critical Peak Electricity Pricing

    OpenAIRE

    Letzler, Robert

    2007-01-01

    This project extends the idea that policy makers should address problems by improving economic incentives. This project adds that presenting incentives in a way that reflects how people make decisions can sometimes improve consumers’ responses to the incentives and policy outcomes. This paper uses behavioral economics to propose ways to increase electricity policy effectiveness. The cost of generating power fluctuates enormously from hour to hour but most customers pay time-invariant prices f...

  1. Safe communities in China as a strategy for injury prevention and safety promotion programmes in the era of rapid economic growth.

    Science.gov (United States)

    Wang, Shu-Mei; Dalal, Koustuv

    2013-02-01

    Due to its rapid economic development, China is facing a huge health, social, and economic burden resulting from injuries. The study's objective was to examine Safe Communities in China as a strategy for injury prevention and safety promotion programmes in the era of rapid economic growth. Literature searches in English and Chinese, which included grey literature, were performed on the Chinese Journal Full-text Search System and Medline, using the words "Safe Community", "injury", "economics", and "prevention". The results showed that the existing 35 recognized members of the International Safe Community Network have not placed due emphasis on suicide prevention, which is one of the leading problems in both rural and urban China. A few groups, such as children, the elderly, cyclists, and pedestrians, have received due emphasis, while other vulnerable groups, such as migrant workers, motorcyclists, students, players, and farmers have not received the necessary attention from the Safe Community perspective. As the evidence describes, Safe Communities in China can be a very effective strategy for injury prevention, but four aspects need to be strengthened in the future: (1) establish and strengthen the policy and regulations in terms of injury prevention at the national level; (2) create a system to involve professional organizations and personnel in projects; (3) consider the economic development status of different parts of China; and (4) intentional injury prevention should receive greater attention.

  2. Long-Term Urban Market Dynamics Reveal Increased Bushmeat Carcass Volume despite Economic Growth and Proactive Environmental Legislation on Bioko Island, Equatorial Guinea

    Science.gov (United States)

    Cronin, Drew T.; Woloszynek, Stephen; Morra, Wayne A.; Honarvar, Shaya; Linder, Joshua M.; Gonder, Mary Katherine; O’Connor, Michael P.; Hearn, Gail W.

    2015-01-01

    Bushmeat hunting is extensive in west and central Africa as both a means for subsistence and for commercial gain. Commercial hunting represents one of the primary threats to wildlife in the region, and confounding factors have made it challenging to examine how external factors influence the commercial bushmeat trade. Bioko Island, Equatorial Guinea is a small island with large tracts of intact forest that support sizeable populations of commercially valuable vertebrates, especially endemic primates. The island also has a low human population and has experienced dramatic economic growth and rapid development since the mid-1990’s. From October 1997 – September 2010, we monitored the largest bushmeat market on Bioko in Malabo, recording over 197,000 carcasses for sale. We used these data to analyze the dynamics of the market in relation to political events, environmental legislation, and rapid economic growth. Our findings suggest that bushmeat hunting and availability increased in parallel with the growth of Equatorial Guinea’s GDP and disposable income of its citizens. During this 13-year study, the predominant mode of capture shifted from trapping to shotguns. Consequently, carcass volume and rates of taxa typically captured with shotguns increased significantly, most notably including intensified hunting of Bioko's unique and endangered monkey fauna. Attempts to limit bushmeat sales, including a 2007 ban on primate hunting and trade, were only transiently effective. The hunting ban was not enforced, and was quickly followed by a marked increase in bushmeat hunting compared to hunting rates prior to the ban. Our results emphasize the negative impact that rapid development and unenforced legislation have had on Bioko’s wildlife, and demonstrate the need for strong governmental support if conservation strategies are to be successful at preventing extinctions of tropical wildlife. PMID:26230504

  3. Rapid Economic Growth and Natural Gas Consumption Nexus: Looking forward from Perspective of 11th Malaysian Plan

    Science.gov (United States)

    Bekhet, H. A.; Yasmin, T.

    2016-03-01

    The present study investigates the relationship between economic growth and energy consumption by incorporating CO2 emissions, natural gas consumption and population in Malaysia. Annual data and F-bound test and granger causality have applied to test the existence of long run relationship between the series. The results show that variables are cointegrated for long run relationship. The results also indicate that natural gas consumption is an important contributing factor to energy demand and hence economic growth in case of Malaysia. The causality analysis highlights that the feedback hypothesis exists between economic growth and energy consumption. While, conservative hypothesis is validated between natural gas consumption and economic growth which implies that economic growth will push natural gas consumption policies in future. This study opens up new direction for policy makers to formulate a comprehensive natural gas policy to sustain environment for long span of time in case to achieve 11th MP targets.

  4. Large-scale deployment of seed treatments has driven rapid increase in use of neonicotinoid insecticides and preemptive pest management in US field crops.

    Science.gov (United States)

    Douglas, Margaret R; Tooker, John F

    2015-04-21

    Neonicotinoids are the most widely used class of insecticides worldwide, but patterns of their use in the U.S. are poorly documented, constraining attempts to understand their role in pest management and potential nontarget effects. We synthesized publicly available data to estimate and interpret trends in neonicotinoid use since their introduction in 1994, with a special focus on seed treatments, a major use not captured by the national pesticide-use survey. Neonicotinoid use increased rapidly between 2003 and 2011, as seed-applied products were introduced in field crops, marking an unprecedented shift toward large-scale, preemptive insecticide use: 34-44% of soybeans and 79-100% of maize hectares were treated in 2011. This finding contradicts recent analyses, which concluded that insecticides are used today on fewer maize hectares than a decade or two ago. If current trends continue, neonicotinoid use will increase further through application to more hectares of soybean and other crop species and escalation of per-seed rates. Alternatively, our results, and other recent analyses, suggest that carefully targeted efforts could considerably reduce neonicotinoid use in field crops without yield declines or economic harm to farmers, reducing the potential for pest resistance, nontarget pest outbreaks, environmental contamination, and harm to wildlife, including pollinator species.

  5. Does increase in the depreciation expensing allowance spur economic growth? Evidence from USA

    Directory of Open Access Journals (Sweden)

    Xiaoli Yuan

    2016-07-01

    Full Text Available Despite substantial evidence that economic growth is influenced by taxation, the impact of Section 179 on GDP is unclear. Section 179 of the Internal Revenue Code enacted in 1958 has operated for several decades in the United States. In addition, in late 2010, two congressional acts affecting Section 179 have been passed, i.e. The Tax Relief Act of 2010 and The Small Business Jobs Act of 2010. The essence of these adoptions is to provide incentives for corporate as well as individual taxpayers. However, there are concerns as to the degree of economic growth these adoptions will provide. This research is therefore focused on showing the correlation between these Section 179 deductions, depreciation and economic growth as the Section 179 figures are debated and changed annually. The study suggests that annual increments of capital depreciation deductions will aid corporate growth as well as other variables that affect economic growth in the United States. However, the benefits for small business are lower than for corporations.

  6. METHODS OF INCREASING THE ROLE OF THE CORPORATE TAX IN THE ECONOMIC AND SOCIAL DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Abrudan Leonard Calin

    2009-05-01

    Full Text Available In this paper we will discuss about the implications of the corporate tax in the field of economical and social development. In the beginning we will present the results of the introduction of the new quota (16% as budgetary receipts and after that we wi

  7. Using agent based modeling to assess the effect of increased Bus Rapid Transit system infrastructure on walking for transportation.

    Science.gov (United States)

    Lemoine, Pablo D; Cordovez, Juan Manuel; Zambrano, Juan Manuel; Sarmiento, Olga L; Meisel, Jose D; Valdivia, Juan Alejandro; Zarama, Roberto

    2016-07-01

    The effect of transport infrastructure on walking is of interest to researchers because it provides an opportunity, from the public policy point of view, to increase physical activity (PA). We use an agent based model (ABM) to examine the effect of transport infrastructure on walking. Particular relevance is given to assess the effect of the growth of the Bus Rapid Transit (BRT) system in Bogotá on walking. In the ABM agents are assigned a home, work location, and socioeconomic status (SES) based on which they are assigned income for transportation. Individuals must decide between the available modes of transport (i.e., car, taxi, bus, BRT, and walking) as the means of reaching their destination, based on resources and needed travel time. We calibrated the model based on Bogota's 2011 mobility survey. The ABM results are consistent with previous empirical findings, increasing BRT access does indeed increase the number of minutes that individuals walk for transportation, although this effect also depends on the availability of other transport modes. The model indicates a saturation process: as more BRT lanes are added, the increment in minutes walking becomes smaller, and eventually the walking time decreases. Our findings on the potential contribution of the expansion of the BRT system to walking for transportation suggest that ABMs may prove helpful in designing policies to continue promoting walking. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. FINANCIAL-ECONOMIC INTEGRATION AS A TOOL FOR INCREASE OF INVESTMENT SUPPORT OF AGRO-INDUSTRIAL PRODUCTION

    Directory of Open Access Journals (Sweden)

    E. R. Zakirova

    2017-01-01

    Full Text Available The article reveals the essence and systematizes the advantages of financial and economic integration. In the agro-industrial complex, this kind of integration contributes to attracting investments and reducing risks for investors, increasing the competitiveness and economic growth of the region. The relevance of the study is due to insufficiently researched remains many aspects of the functioning of integrated business systems in relation to individual industries, in particular, to agroindustrial production. The aim of the article is to study theoretical approaches to the essence of financial and economic integration in agro-industrial production and analyze the mechanism of investment support for the Russian agrarian sector, taking into account financial and economic integration. In preparing the article, general scientific methods of research were used: analysis and synthesis, generalization, comparison, classification. Results. The interpretation of financial and economic integration in Russian and foreign scientific publications is generalized. Distinctions of financial and economic integration are distinguished from other economic processes. The advantages of financial and economic integration for the economy and business entities are systematized. The importance of integrating industries and business entities in the agro-industrial complex, which is of strategic importance for ensuring Russia's food security, was noted. The branch structure of the agro-industrial complex is analyzed. The scheme of the integrated financial and economic mechanism in the agroindustrial complex is described. The importance of an optimal balance between cooperation and integration was underscored. The insufficiency of the methodological level of studies of agro-industrial integration is grounded. The components of the effect of financial and economic integration are considered. Positive effects of integration processes in the agroindustrial complex are

  9. Anchorage onto deciduous teeth: effectiveness of early rapid maxillary expansion in increasing dental arch dimension and improving anterior crowding.

    Science.gov (United States)

    Mutinelli, Sabrina; Manfredi, Mario; Guiducci, Antonio; Denotti, Gloria; Cozzani, Mauro

    2015-01-01

    Anchorage onto permanent dentition is a common procedure in rapid maxillary expansion. However, replacing first permanent molars with the second deciduous molars seems to be an option to reduce some negative side effects during orthodontic treatment. The purpose of this study was to evaluate the dental effect of rapid maxillary expansion with anchorage exclusively onto deciduous teeth performed in the first period of transition. Twenty patients with a lateral cross-bite treated exclusively by a Haas expander in early mixed dentition were retrospectively analyzed before treatment, at appliance removal, and at 21 months out of retention. The sagittal and transverse dimensions, together with the inter-canine arch and irregularity index, were digitally measured on scanned images of dental casts. The patients were compared with three balanced control groups (in total, 60 individuals) matched for gender. Two control groups had the same canine dental class as the treated group at T1, were in the inter-transitional period, and either had or lacked a lateral cross-bite. The last control group was comprised of adolescents in permanent dentition with a dental class I. The statistical analysis was performed by means of repeated-measures ANOVA for paired data and one-way ANOVA, the Kruskal-Wallis test, and the Mann-Whitney test for independent measures (α-level p dentition), the dental arch dimensions of treated patients were similar to those of adolescents with a dental class I and significantly wider than those of patients with a lateral cross-bite. Also, the anterior irregularity index was lower among patients who had undergone expansion treatments than in all untreated study participants. The Haas expander anchored to the deciduous teeth is effective in increasing the dental arch width in patients with a lateral cross-bite. The dimensions of the dental arch were modified earlier toward the values of the permanent dentition.

  10. Yersinia pestis endowed with increased cytotoxicity is avirulent in a bubonic plague model and induces rapid protection against pneumonic plague.

    Directory of Open Access Journals (Sweden)

    Ayelet Zauberman

    Full Text Available An important virulence strategy evolved by bacterial pathogens to overcome host defenses is the modulation of host cell death. Previous observations have indicated that Yersinia pestis, the causative agent of plague disease, exhibits restricted capacity to induce cell death in macrophages due to ineffective translocation of the type III secretion effector YopJ, as opposed to the readily translocated YopP, the YopJ homologue of the enteropathogen Yersinia enterocolitica Oratio8. This led us to suggest that reduced cytotoxic potency may allow pathogen propagation within a shielded niche, leading to increased virulence. To test the relationship between cytotoxic potential and virulence, we replaced Y. pestis YopJ with YopP. The YopP-expressing Y. pestis strain exhibited high cytotoxic activity against macrophages in vitro. Following subcutaneous infection, this strain had reduced ability to colonize internal organs, was unable to induce septicemia and exhibited at least a 10(7-fold reduction in virulence. Yet, upon intravenous or intranasal infection, it was still as virulent as the wild-type strain. The subcutaneous administration of the cytotoxic Y. pestis strain appears to activate a rapid and potent systemic, CTL-independent, immunoprotective response, allowing the organism to overcome simultaneous coinfection with 10,000 LD(50 of virulent Y. pestis. Moreover, three days after subcutaneous administration of this strain, animals were also protected against septicemic or primary pneumonic plague. Our findings indicate that an inverse relationship exists between the cytotoxic potential of Y. pestis and its virulence following subcutaneous infection. This appears to be associated with the ability of the engineered cytotoxic Y. pestis strain to induce very rapid, effective and long-lasting protection against bubonic and pneumonic plague. These observations have novel implications for the development of vaccines/therapies against Y. pestis and shed

  11. Rapid land use change after socio-economic disturbances: the collapse of the Soviet Union versus Chernobyl

    International Nuclear Information System (INIS)

    Hostert, Patrick; Kuemmerle, Tobias; Sieber, Anika; Prishchepov, Alexander; Lambin, Eric F; Radeloff, Volker C

    2011-01-01

    Land use change is a principal force and inherent element of global environmental change, threatening biodiversity, natural ecosystems, and their services. However, our ability to anticipate future land use change is severely limited by a lack of understanding of how major socio-economic disturbances (e.g., wars, revolutions, policy changes, and economic crises) affect land use. Here we explored to what extent socio-economic disturbances can shift land use systems onto a different trajectory, and whether this can result in less intensive land use. Our results show that the collapse of the Soviet Union in 1991 caused a major reorganization in land use systems. The effects of this socio-economic disturbance were at least as drastic as those of the nuclear disaster in the Chernobyl region in 1986. While the magnitudes of land abandonment were similar in Ukraine and Belarus in the case of the nuclear disaster (28% and 36% of previously farmed land, respectively), the rates of land abandonment after the collapse of the Soviet Union in Ukraine were twice as high as those in Belarus. This highlights that national policies and institutions play an important role in mediating effects of socio-economic disturbances. The socio-economic disturbance that we studied caused major hardship for local populations, yet also presents opportunities for conservation, as natural ecosystems are recovering on large areas of former farmland. Our results illustrate the potential of socio-economic disturbances to revert land use intensification and the important role institutions and policies play in determining land use systems' resilience against such socio-economic disturbances.

  12. Rapid land use change after socio-economic disturbances: the collapse of the Soviet Union versus Chernobyl

    Science.gov (United States)

    Hostert, Patrick; Kuemmerle, Tobias; Prishchepov, Alexander; Sieber, Anika; Lambin, Eric F.; Radeloff, Volker C.

    2011-10-01

    Land use change is a principal force and inherent element of global environmental change, threatening biodiversity, natural ecosystems, and their services. However, our ability to anticipate future land use change is severely limited by a lack of understanding of how major socio-economic disturbances (e.g., wars, revolutions, policy changes, and economic crises) affect land use. Here we explored to what extent socio-economic disturbances can shift land use systems onto a different trajectory, and whether this can result in less intensive land use. Our results show that the collapse of the Soviet Union in 1991 caused a major reorganization in land use systems. The effects of this socio-economic disturbance were at least as drastic as those of the nuclear disaster in the Chernobyl region in 1986. While the magnitudes of land abandonment were similar in Ukraine and Belarus in the case of the nuclear disaster (28% and 36% of previously farmed land, respectively), the rates of land abandonment after the collapse of the Soviet Union in Ukraine were twice as high as those in Belarus. This highlights that national policies and institutions play an important role in mediating effects of socio-economic disturbances. The socio-economic disturbance that we studied caused major hardship for local populations, yet also presents opportunities for conservation, as natural ecosystems are recovering on large areas of former farmland. Our results illustrate the potential of socio-economic disturbances to revert land use intensification and the important role institutions and policies play in determining land use systems' resilience against such socio-economic disturbances.

  13. Rapid land use change after socio-economic disturbances: the collapse of the Soviet Union versus Chernobyl

    Energy Technology Data Exchange (ETDEWEB)

    Hostert, Patrick; Kuemmerle, Tobias; Sieber, Anika [Geography Department, Humboldt-Universitaet zu Berlin, Unter den Linden 6, 10099 Berlin (Germany); Prishchepov, Alexander [Leibniz Institute of Agricultural Development in Central and Eastern Europe (IAMO), Department of Structural Development of Farms and Rural Areas, Theodor-Lieser-Strasse 2, 06120 Halle (Germany); Lambin, Eric F [Earth and Life Institute, Universite catholique de Louvain, place L. Pasteur 3, B-1348 Louvain-la-Neuve (Belgium); Radeloff, Volker C, E-mail: patrick.hostert@geo.hu-berlin.de [Department of Forest and Wildlife Ecology, University of Wisconsin-Madison, 1630 Linden Drive, Madison, WI 53706-1598 (United States)

    2011-10-15

    Land use change is a principal force and inherent element of global environmental change, threatening biodiversity, natural ecosystems, and their services. However, our ability to anticipate future land use change is severely limited by a lack of understanding of how major socio-economic disturbances (e.g., wars, revolutions, policy changes, and economic crises) affect land use. Here we explored to what extent socio-economic disturbances can shift land use systems onto a different trajectory, and whether this can result in less intensive land use. Our results show that the collapse of the Soviet Union in 1991 caused a major reorganization in land use systems. The effects of this socio-economic disturbance were at least as drastic as those of the nuclear disaster in the Chernobyl region in 1986. While the magnitudes of land abandonment were similar in Ukraine and Belarus in the case of the nuclear disaster (28% and 36% of previously farmed land, respectively), the rates of land abandonment after the collapse of the Soviet Union in Ukraine were twice as high as those in Belarus. This highlights that national policies and institutions play an important role in mediating effects of socio-economic disturbances. The socio-economic disturbance that we studied caused major hardship for local populations, yet also presents opportunities for conservation, as natural ecosystems are recovering on large areas of former farmland. Our results illustrate the potential of socio-economic disturbances to revert land use intensification and the important role institutions and policies play in determining land use systems' resilience against such socio-economic disturbances.

  14. Increasing economic stability of the industrial enterprise as a result of its market value modeling

    Directory of Open Access Journals (Sweden)

    Efimova M.G.

    2017-01-01

    Full Text Available The article deals with an urgent problem of the Russian and global economic stability. The issues of management of the modern industrial enterprise in the conditions of variable economy are considered in this research. Also the article highlights the importance of evaluation of industrial enterprises in Russia nowadays. The management model of the industrial enterprise cost based on sustainability criteria is constructed. The author focuses on new approaches to mathematic modeling of business evaluation. The article contains graphs and charts related to performance of enterprise system and different business strategies based on economic sustainability. Relevant problems of management by means of business assessment for enterprises owners and top managers are defined. The aim of the article is to suggest measures for the Russian industry to manage the cost of enterprises and consequently, to make national economy management more effective.

  15. Getting Risks Right:Thoughts about Increasing the Resilience of the Global Social & Economic System

    Directory of Open Access Journals (Sweden)

    Patrick Liedtke

    2012-04-01

    Full Text Available The extraordinary extent of the financial crisis has inspired deep systemic reforms world-wide, rethinking financial stability, the resilience of our economic systems, and the role that national and international institutions play. While most of the ongoing activities are understandably centred on banks and the banking sector – the origin and centre of the crisis – other important elements have been relegated into secondary roles and fundamental democratic processes have been sidelined. Financial issues have crowded out real economic issues as policy-makers and politicians spend more time on the financial than the substantial (i.e. the real economy and the democratic. Two fundamental concerns need to be addressed proactively: 1. A comprehensive approach to deal with both financial and real world risks on this planet, and 2. The global governance system based on democratic principles to follow globalisation of the business (and particularly the financial sector.

  16. Nicotine reduction as an increase in the unit price of cigarettes: A behavioral economics approach

    OpenAIRE

    Smith, Tracy T.; Sved, Alan F.; Hatsukami, Dorothy K.; Donny, Eric C.

    2014-01-01

    Urgent action is needed to reduce the harm caused by smoking. Product standards that reduce the addictiveness of cigarettes are now possible both in the U.S. and in countries party to the Framework Convention on Tobacco Control. Specifically, standards that required substantially reduced nicotine content in cigarettes could enable cessation in smokers and prevent future smoking among current non-smokers. Behavioral economics uses principles from the field of microeconomics to characterize how...

  17. Increasing Feedstock Production for Biofuels: Economic Drivers, Environmental Implications, and the Role of Research

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2009-10-27

    The Biomass Research and Development Board (Board) commissioned an economic analysis of feedstocks to produce biofuels. The Board seeks to inform investments in research and development needed to expand biofuel production. This analysis focuses on feedstocks; other interagency teams have projects underway for other parts of the biofuel sector (e.g., logistics). The analysis encompasses feedstocks for both conventional and advanced biofuels from agriculture and forestry sources.

  18. Economic Analysis Supporting the Increase of the Unspecified Minor Military Construction Threshold

    Science.gov (United States)

    2016-06-01

    rates. Some even go as far as including productivity rates, taxes and insurance costs . A complete breakdown, conducted by OSD, of all the major indices...of technical solution. (6) Completeness of scope and cost estimate. (7) Adequacy of economic analysis (when required). (8) Compliance with the...and to the Office of Management and Budget, Paperwork Reduction Project (0704-0188) Washington, DC 20503. 1. AGENCY USE ONLY (Leave blank) 2

  19. Economic Analysis of Cikaso Mini Hydro Power Plant as a CDM Project for Increasing IRR

    OpenAIRE

    Febijanto, Irhan

    2013-01-01

    Renewable energy fueled power generations are few developed by private sector in Indonesia. High-cost investment and low electricity selling price to PT PLN as a single buyer is main barriers for private sector to involve in the development of renewable energy fueled power generations. In this project, the economic feasibility of Mini Hydro Power Plant of Cikaso with capacity of 5.3 MW, located at Sukabumi Regency, West Java province was assessed. This project utilized revenue generated from ...

  20. 78 FR 77141 - U.S. Customs and Border Protection 2014 East Coast Trade Symposium: “Increasing Economic...

    Science.gov (United States)

    2013-12-20

    ..., 2013. Maria Luisa Boyce, Senior Advisor for Private Sector Engagement, Executive Director, Office of... Protection 2014 East Coast Trade Symposium: ``Increasing Economic Competitiveness Through Global Partnership... Competitiveness Through Global Partnership and Innovation.'' The format of the East Coast Trade Symposium will be...

  1. Renewal of Collaborative Research: Economically Viable Forest Harvesting Practices That Increase Carbon Sequestration

    Energy Technology Data Exchange (ETDEWEB)

    Davidson, E.A.; Dail, D.B., Hollinger, D.; Scott, N.; Richardson, A.

    2012-08-02

    Forests provide wildlife habitat, water and air purification, climate moderation, and timber and nontimber products. Concern about climate change has put forests in the limelight as sinks of atmospheric carbon. The C stored in the global vegetation, mostly in forests, is nearly equivalent to the amount present in atmospheric CO{sub 2}. Both voluntary and government-mandated carbon trading markets are being developed and debated, some of which include C sequestration resulting from forest management as a possible tradeable commodity. However, uncertainties regarding sources of variation in sequestration rates, validation, and leakage remain significant challenges for devising strategies to include forest management in C markets. Hence, the need for scientifically-based information on C sequestration by forest management has never been greater. The consequences of forest management on the US carbon budget are large, because about two-thirds of the {approx}300 million hectare US forest resource is classified as 'commercial forest.' In most C accounting budgets, forest harvesting is usually considered to cause a net release of C from the terrestrial biosphere to the atmosphere. However, forest management practices could be designed to meet the multiple goals of providing wood and paper products, creating economic returns from natural resources, while sequestering C from the atmosphere. The shelterwood harvest strategy, which removes about 30% of the basal area of the overstory trees in each of three successive harvests spread out over thirty years as part of a stand rotation of 60-100 years, may improve net C sequestration compared to clear-cutting because: (1) the average C stored on the land surface over a rotation increases, (2) harvesting only overstory trees means that a larger fraction of the harvested logs can be used for long-lived sawtimber products, compared to more pulp resulting from clearcutting, (3) the shelterwood cut encourages growth of

  2. A contingency safe, responsible, economic, increased capacity spent nuclear fuel (SNF) advance fuel cycle

    International Nuclear Information System (INIS)

    Levy, S.

    2008-01-01

    The purpose of this paper is to have an Advanced Light Water (LWR) fuel cycle and an associated development program to provide a contingency plan to the current DOE effort to license once-through spent Light Water Reactor (LWR) fuel for disposition at Yucca Mountain (YM). The intent is to fully support the forthcoming June 2008 DOE submittal to the Nuclear Regulatory Commission (NRC) based upon the latest DOE draft DOE/EIS-0250F-SID dated October 2007 which shows that the latest DOE YM doses would readily satisfy the anticipated NRC and Environmental Protection Agency (EP) standards. The proposed Advance Fuel Cycle can offer potential resolution of obstacles that might arise during the NRC review and, particularly, during the final hearings process to be held in Nevada. Another reason for the proposed concept is that a substantial capacity growth of the YM repository will be necessary to accommodate the SNF of Advance Light Water Reactors (ALWRs) currently under consideration for United States (U.S.) electricity production (1) and the results of the recently issued study by the Electric Power Research Institute (EPRI) to reduce CO 2 emissions (2). That study predicts that by 2030 U.S. nuclear power generation would grow by 64 Gigawatt electrical (GWe) and account for 25.5 percent of the overall U.S. electrical generation. The current annual SNF once-through fuel cycle accumulation would rise from 2000-2100 MT (Metric Tons) to about 3480 MT in 2030 and the total SNF inventory, would reach nearly 500,000 MT by 2100 if U. S. nuclear power continues to grow at 1.1 percent per year after 2030. That last projection does not account for any SNF reduction due to increased fuel burnup or any increased capacity needed 'to establish supply Global Nuclear Energy Partnership (GNEP,) arrangements among nations to provide nuclear fuel and taking back spent fuel for recycling without spreading enrichment and reprocessing technologies' (3). The anticipated capacity of 120 MT

  3. Energy price increases, economic rents, and industrial structure in a small regional economy

    Energy Technology Data Exchange (ETDEWEB)

    Norrie, K.H.; Percy, M.B.

    1982-01-01

    The authors model the relationship between natural-resource revenues and regional economic diversification in the context of a general-equilibrium model of a small, open, natural-resource-based regional economy. The model is then used to stimulate the implications of various province-building strategies, and to draw policy implications from this. They find that the efforts to diversify the economy using the fiscal capacity of the region will, in general, impose real welfare losses on the residents of the province, although certain groups, such as land owners, are already better off.

  4. Rapid ecological shift following piscivorous fish introduction to increasingly eutrophic and warmer Lake Furnas (Azores Archipelago, Portugal): A paleoecological approach

    DEFF Research Database (Denmark)

    Buchaca, Teresa; Skov, Tue; Amsinck, Susanne Lildal

    2011-01-01

    Lake ecosystems are nowadays often subjected to multi-stressors, such as eutrophication, climate change, and fish manipulations, the effects of which can be difficult to disentangle, not least from the usual short-term limnological time-series that are available. However, multi-proxy paleoecologi......Lake ecosystems are nowadays often subjected to multi-stressors, such as eutrophication, climate change, and fish manipulations, the effects of which can be difficult to disentangle, not least from the usual short-term limnological time-series that are available. However, multi......, meteorological forcing, and fish species introduction for recent lake ecosystem development in Lake Furnas on the island of Sa˜o Miguel, the Azores. The lake was stocked with cyprinids in the late nineteenth century and recently also with piscivorous fish, and has been affected by increasing agricultural......, and cryptophytes. The composition of microbial and algal assemblages changed rapidly after Daphnia appearance, and the covariance between fish stocking, nutrient loading, and enhanced temperatures captured most of the variability in algae accumulation, and thus likely in lake primary production as well. Thus, lake...

  5. Caffeine ingestion after rapid weight loss in judo athletes reduces perceived effort and increases plasma lactate concentration without improving performance.

    Science.gov (United States)

    Lopes-Silva, Joao P; Felippe, Leandro J C; Silva-Cavalcante, Marcos D; Bertuzzi, Romulo; Lima-Silva, Adriano E

    2014-07-22

    The objective of this study was to examine the effect of caffeine on judo performance, perceived exertion, and plasma lactate response when ingested during recovery from a 5-day weight loss period. Six judokas performed two cycles of a 5-day rapid weight loss procedure to reduce their body weight by ~5%. After weigh-in, subjects re-fed and rehydrated over a 4-h recovery period. In the third hour of this "loading period", subjects ingested a capsule containing either caffeine (6 mg·kg-1) or placebo. One hour later, participants performed three bouts of a judo fitness test with 5-min recovery periods. Perceived exertion and plasma lactate were measured before and immediately after each test bout. Body weight was reduced in both caffeine and placebo conditions after the weight loss period (-3.9% ± 1.6% and -4.0% ± 2.3% from control, respectively, p caffeine or placebo groups. However, plasma lactate was systemically higher and perceived exertion lower in the subjects who ingested caffeine compared to either the control or placebo subjects (p caffeine did not improve performance during the judo fitness test after a 5-day weight loss period, but reduced perceived exertion and increased plasma lactate.

  6. German enterprises and the changes in energy economics due to increased concerns regarding environmental sustainability

    Directory of Open Access Journals (Sweden)

    Weber Gregor

    2015-06-01

    Full Text Available This article is part of a first year doctoral research regarding the current state of knowledge in environmental sustainability, energy economics and their impact on European enterprises. As the current changes and modifications of the German energy economics system are observed by people all around the globe, the current paper analyzes what has been said until now in the scientific literature on character of the new strategy for energy consumption and production in Germany and its impact on environmental and social sustainability. With the help of two questionnaire-based surveys conducted in 2013 and 2014 through the German DIHK1, German enterprises were surveyed in order to: identify potential differences and similarities between the two periods, identify the effects of the energy transition on companies’ profitability, and analyze these effects and compare the results in terms of potential trend developments. The research findings confirmed that changes in the energy system affect not only the environmental sustainability only, but also the economy, in some cases even independent of the stage in which the changing system of the economy presently is.

  7. [Ecological risk assessment of human activity of rapid economic development regions in southern Jiangsu, China: a case study of Dantu District of Zhenjiang City].

    Science.gov (United States)

    Fang, Guang-Ling; Xiang, Bao; Wang, Bao-Liang; Jin, Xia; Hu, Yu; Zhang, Li-Kun

    2014-04-01

    This article investigated the spatiotemporal variation of landscape ecological risk in Dantu District of Zhenjiang City with statistical method based on the ETM remote sensing data in 2000 and 2005, and the TM remote sensing data in 2010, and quantitative index of regional ecological risk assessment was established with the employment of landscape index, so as to enhance the ecosystem management, prevent and reduce the regional ecological risk in southern Jiangsu with rapid economic development. The results showed that the fragmentations, divergence, and ecological losses of natural landscape types, such as forestland, wetland, waters, etc., were deteriorated with the expansion of built-up lands from 2000 to 2010. The higher ecological risk zone took up 5.7%, 9.0%, and 10.2% of the whole region in 2000, 2005, and 2010, respectively, which mainly distributed in the plain hilly region. During the study period, the area aggravating to the higher ecological risk zone was approximately 296.2 km2, 48% of the whole region. The ecological risk rose up in most of the region. The interference of rapid economic development to landscape patterns was even more intensive, with obvious spatial differences in ecological risk distribution. The measures of exploiting resources near the port, utilizing natural wetlands, constructing industrial parks, and rapid urbanization, etc., intensified the ecological risk and accelerated the conversion rate. Prompt strategies should be established to manage the ecological risk of this region.

  8. SMS messages increase adherence to rapid diagnostic test results among malaria patients: results from a pilot study in Nigeria.

    Science.gov (United States)

    Modrek, Sepideh; Schatzkin, Eric; De La Cruz, Anna; Isiguzo, Chinwoke; Nwokolo, Ernest; Anyanti, Jennifer; Ujuju, Chinazo; Montagu, Dominic; Liu, Jenny

    2014-02-25

    The World Health Organization now recommends parasitological confirmation for malaria case management. Rapid diagnostic tests (RDTs) for malaria are an accurate and simple diagnostic to confirm parasite presence in blood. However, where they have been deployed, adherence to RDT results has been poor, especially when the test result is negative. Few studies have examined adherence to RDTs distributed or purchased through the private sector. The Rapid Examination of Malaria and Evaluation of Diagnostic Information (REMEDI) study assessed the acceptability of and adherence to RDT results for patients seeking care from private sector drug retailers in two cities in Oyo State in south-west Nigeria. In total, 465 adult participants were enrolled upon exit from a participating drug shop having purchased anti-malaria drugs for themselves. Participants were given a free RDT and the appropriate treatment advice based on their RDT result. Short Message Service (SMS) text messages reiterating the treatment advice were sent to a randomly selected half of the participants one day after being tested. Participants were contacted via phone four days after the RDT was conducted to assess adherence to the RDT information and treatment advice. Adherence to RDT results was 14.3 percentage points (P-val <0.001) higher in the treatment group who were sent the SMS. The higher adherence in the treatment group was robust to several specification tests and the estimated difference in adherence ranged from 9.7 to 16.1 percentage points. Further, the higher adherence to the treatment advice was specific to the treatment advice for anti-malarial drugs and not other drugs purchased to treat malaria symptoms in the RDT-negative participants who bought both anti-malarial and symptom drugs. There was no difference in adherence for the RDT-positive participants who were sent the SMS. SMS text messages substantially increased adherence to RDT results for patients seeking care for malaria from

  9. Caffeine Ingestion after Rapid Weight Loss in Judo Athletes Reduces Perceived Effort and Increases Plasma Lactate Concentration without Improving Performance

    Directory of Open Access Journals (Sweden)

    Joao P. Lopes-Silva

    2014-07-01

    Full Text Available The objective of this study was to examine the effect of caffeine on judo performance, perceived exertion, and plasma lactate response when ingested during recovery from a 5-day weight loss period. Six judokas performed two cycles of a 5-day rapid weight loss procedure to reduce their body weight by ~5%. After weigh-in, subjects re-fed and rehydrated over a 4-h recovery period. In the third hour of this “loading period”, subjects ingested a capsule containing either caffeine (6 mg·kg−1 or placebo. One hour later, participants performed three bouts of a judo fitness test with 5-min recovery periods. Perceived exertion and plasma lactate were measured before and immediately after each test bout. Body weight was reduced in both caffeine and placebo conditions after the weight loss period (−3.9% ± 1.6% and −4.0% ± 2.3% from control, respectively, p < 0.05. At three hours after weigh-in, body weight had increased with both treatments but remained below the control (−3.0% ± 1.3% and −2.7% ± 2.2%. There were no significant differences in the number of throws between the control, caffeine or placebo groups. However, plasma lactate was systemically higher and perceived exertion lower in the subjects who ingested caffeine compared to either the control or placebo subjects (p < 0.05. In conclusion, caffeine did not improve performance during the judo fitness test after a 5-day weight loss period, but reduced perceived exertion and increased plasma lactate.

  10. A predictive modeling approach to increasing the economic effectiveness of disease management programs.

    Science.gov (United States)

    Bayerstadler, Andreas; Benstetter, Franz; Heumann, Christian; Winter, Fabian

    2014-09-01

    Predictive Modeling (PM) techniques are gaining importance in the worldwide health insurance business. Modern PM methods are used for customer relationship management, risk evaluation or medical management. This article illustrates a PM approach that enables the economic potential of (cost-) effective disease management programs (DMPs) to be fully exploited by optimized candidate selection as an example of successful data-driven business management. The approach is based on a Generalized Linear Model (GLM) that is easy to apply for health insurance companies. By means of a small portfolio from an emerging country, we show that our GLM approach is stable compared to more sophisticated regression techniques in spite of the difficult data environment. Additionally, we demonstrate for this example of a setting that our model can compete with the expensive solutions offered by professional PM vendors and outperforms non-predictive standard approaches for DMP selection commonly used in the market.

  11. Anchorage onto deciduous teeth: effectiveness of early rapid maxillary expansion in increasing dental arch dimension and improving anterior crowding

    OpenAIRE

    Mutinelli, Sabrina; Manfredi, Mario; Guiducci, Antonio; Denotti, Gloria; Cozzani, Mauro

    2015-01-01

    Background Anchorage onto permanent dentition is a common procedure in rapid maxillary expansion. However, replacing first permanent molars with the second deciduous molars seems to be an option to reduce some negative side effects during orthodontic treatment. The purpose of this study was to evaluate the dental effect of rapid maxillary expansion with anchorage exclusively onto deciduous teeth performed in the first period of transition. Methods Twenty patients with a lateral cross-bite tre...

  12. The association between economic recession and public support for increased tobacco taxation in 27 European countries.

    Science.gov (United States)

    Filippidis, Filippos T; Agaku, Israel T; Vardavas, Constantine I; Majeed, Azeem

    2014-11-01

    Increased taxation on tobacco products is an effective method of reducing tobacco use. This study assessed population support among respondents aged ≥15 years, from 27 European Union (EU) countries for increased taxation and other tobacco control measures during the 2009-2012 period. Nationally representative data were obtained from the 2009 (n=26,788) and 2012 (n=26,751) cross-sectional Eurobarometer surveys. Estimates were compared using chi-square statistics. The effect of the relative change in gross domestic product (GDP) on the change in support for increased taxation during 2009-2012 was calculated using the Pearson correlation coefficient and linear regression models. Between 2009 and 2012, population support for increased taxes on tobacco products declined (56.1% to 53.2%; p<0.001). However, support for other tobacco control measures increased significantly. After adjusting for baseline GDP per capita (2009), a 10% increase in GDP per capita was associated with 4.5% increase in support of tax increases. When Latvia and Lithuania were excluded from the analyses (because of their marked deviation from the general trend), there was a strong correlation between the change in GDP and support for increased taxes (ρ=0.64; p<0.001). Also, after adjusting for baseline GDP, support for higher taxes on tobacco increased by 7.0% for every 10% increase in GDP between 2009 and 2012. Population support for tax increases declined in the EU between 2009 and 2012, especially in countries with declines in GDP nonetheless, public support for other tobacco control measures remains high, thus indicating a viable environment for more comprehensive tobacco control. © 2014 the Nordic Societies of Public Health.

  13. Evaluating the influence of increasing block tariffs in residential gas sector using agent-based computational economics

    International Nuclear Information System (INIS)

    Gong, Chengzhu; Yu, Shiwei; Zhu, Kejun; Hailu, Atakelty

    2016-01-01

    Designing a desirable increasing block tariff for the residential gas retail market has been a challenging task for regulated utilities, especially in China. To deal with such problems, in this paper, we establish an agent-based, computational economics system to provide a formal evaluation of the direct and indirect influences of several issued increasing block tariffs in the residential gas market. Moreover, a comprehensive demand response behaviour model has been improved in term of price elasticity, while still coping with income levels and complex social environment. We also compute and compare the outcomes of several increasing block tariffs with the initial flat tariff by running the system on a test-case using real-world data from a middle-scale gas retail market in Wuhan. The results indicate that there is an appropriate increasing block gas tariff scheme that has greater ability to improve social equity while still ensuring operator revenue and promoting gas conservation. In order to offset the limitations of the proposed increasing block tariffs, the regulator should adopt some complementary measures, such as applying appropriate policies targeting the intended consumers, and allowing large families to obtain extra allowance of volume. - Highlights: •Analyse the influence of increasing block tariffs in residential gas sector. •An agent-based computational economics system is utilised for policy analysis. •Increasing block tariff can generate revenue while still promote gas conservation. •The increasing subsidy for low income household can improve the social equity.

  14. Eight new genomes and synthetic controls increase the accessibility of rapid melt-MAMA SNP typing of Coxiella burnetii.

    Directory of Open Access Journals (Sweden)

    Edvin Karlsson

    Full Text Available The case rate of Q fever in Europe has increased dramatically in recent years, mainly because of an epidemic in the Netherlands in 2009. Consequently, there is a need for more extensive genetic characterization of the disease agent Coxiella burnetii in order to better understand the epidemiology and spread of this disease. Genome reference data are essential for this purpose, but only thirteen genome sequences are currently available. Current methods for typing C. burnetii are criticized for having problems in comparing results across laboratories, require the use of genomic control DNA, and/or rely on markers in highly variable regions. We developed in this work a method for single nucleotide polymorphism (SNP typing of C. burnetii isolates and tissue samples based on new assays targeting ten phylogenetically stable synonymous canonical SNPs (canSNPs. These canSNPs represent previously known phylogenetic branches and were here identified from sequence comparisons of twenty-one C. burnetii genomes, eight of which were sequenced in this work. Importantly, synthetic control templates were developed, to make the method useful to laboratories lacking genomic control DNA. An analysis of twenty-one C. burnetii genomes confirmed that the species exhibits high sequence identity. Most of its SNPs (7,493/7,559 shared by >1 genome follow a clonal inheritance pattern and are therefore stable phylogenetic typing markers. The assays were validated using twenty-six genetically diverse C. burnetii isolates and three tissue samples from small ruminants infected during the epidemic in the Netherlands. Each sample was assigned to a clade. Synthetic controls (vector and PCR amplified gave identical results compared to the corresponding genomic controls and are viable alternatives to genomic DNA. The results from the described method indicate that it could be useful for cheap and rapid disease source tracking at non-specialized laboratories, which requires accurate

  15. Importance of bio-medical and socio-economic factors for increase of life expectancy

    Directory of Open Access Journals (Sweden)

    Radivojević Biljana M.

    2004-01-01

    Full Text Available This paper analyzes the connection between life expectancy according to sex and numerous factors on which its level depends on. Statistical analysis understood application of correlation and regression analysis for determining the connection strength of life expectancy and researched factors separately and then all factors together, as well as separately groups of health-medical and socio-economic factors. The analysis was carried out for a group of developed countries, medium developed, mixed group and Yugoslavia (now SCG on available data for the second half of the 20th century. Analysis results for Yugoslavia showed that the greatest influence on life expectancy of all factors together were setting aside funds for social security (p<0.05. If only health-medical factors are observed, then child mortality up to 5 years and tumor mortality are in question. With women, the greatest influence is with child mortality up to five years old among all factors (economic factors on life expectancy was very strong in present conditions of mortality, not only in positive, but in negative direction as well, and that their influence in that second half of the 20th century was greater than the influence of health

  16. Past, Present, and Future of Antibacterial Economics: Increasing Bacterial Resistance, Limited Antibiotic Pipeline, and Societal Implications.

    Science.gov (United States)

    Luepke, Katherine H; Suda, Katie J; Boucher, Helen; Russo, Rene L; Bonney, Michael W; Hunt, Timothy D; Mohr, John F

    2017-01-01

    Growing antimicrobial resistance and a dwindling antibiotic pipeline have resulted in an emerging postantibiotic era, as patients are now dying from bacterial infections that were once treatable. The fast-paced "Golden Age" of antibiotic development that started in the 1940s has lost momentum; from the 1980s to the early 2000s, there was a 90% decline in the approval of new antibiotics as well as the discovery of few new novel classes. Many companies have shifted away from development due to scientific, regulatory, and economic hurdles that proved antibiotic development to be less attractive compared with more lucrative therapeutic areas. National and global efforts are focusing attention toward potential solutions for reinvigorating the antibiotic pipeline and include "push" incentives such as public-private partnerships and "pull" incentives such as reimbursement reform and market exclusivity. Hybrid models of incentives, global coordination among stakeholders, and the appropriate balance of antibiotic pricing, volume of drug used, and proper antimicrobial stewardship are key to maximizing efforts toward drug development to ensure access to patients in need of these therapies. © 2016 Pharmacotherapy Publications, Inc.

  17. Meat Feeding Restricts Rapid Cold Hardening Response and Increases Thermal Activity Thresholds of Adult Blow Flies, Calliphora vicina (Diptera: Calliphoridae.

    Directory of Open Access Journals (Sweden)

    Paul C Coleman

    Full Text Available Virtually all temperate insects survive the winter by entering a physiological state of reduced metabolic activity termed diapause. However, there is increasing evidence that climate change is disrupting the diapause response resulting in non-diapause life stages encountering periods of winter cold. This is a significant problem for adult life stages in particular, as they must remain mobile, periodically feed, and potentially initiate reproductive development at a time when resources should be diverted to enhance stress tolerance. Here we present the first evidence of protein/meat feeding restricting rapid cold hardening (RCH ability and increasing low temperature activity thresholds. No RCH response was noted in adult female blow flies (Calliphora vicina Robineau-Desvoidy fed a sugar, water and liver (SWL diet, while a strong RCH response was seen in females fed a diet of sugar and water (SW only. The RCH response in SW flies was induced at temperatures as high as 10°C, but was strongest following 3h at 0°C. The CTmin (loss of coordinated movement and chill coma (final appendage twitch temperature of SWL females (-0.3 ± 0.5°C and -4.9 ± 0.5°C, respectively was significantly higher than for SW females (-3.2 ± 0.8°C and -8.5 ± 0.6°C. We confirmed this was not directly the result of altered extracellular K+, as activity thresholds of alanine-fed adults were not significantly different from SW flies. Instead we suggest the loss of cold tolerance is more likely the result of diverting resource allocation to egg development. Between 2009 and 2013 winter air temperatures in Birmingham, UK, fell below the CTmin of SW and SWL flies on 63 and 195 days, respectively, suggesting differential exposure to chill injury depending on whether adults had access to meat or not. We conclude that disruption of diapause could significantly impact on winter survival through loss of synchrony in the timing of active feeding and reproductive development with

  18. Strategies for Mitigating the Reduction in Economic Value of Variable Generation with Increasing Penetration Levels

    Energy Technology Data Exchange (ETDEWEB)

    Mills, Andrew; Wiser, Ryan

    2014-03-03

    In this report, we evaluate individual options that have the potential to stem the decline in the marginal value of variable generation (VG) with increasing penetration levels. We focus only on the effectiveness of mitigation measures for wind and PV.

  19. Increasing Access for Economically Disadvantaged Students: The NSF/CSEM & S-STEM Programs at Louisiana State University

    Science.gov (United States)

    Wilson, Zakiya S.; Iyengar, Sitharama S.; Pang, Su-Seng; Warner, Isiah M.; Luces, Candace A.

    2012-10-01

    Increasing college degree attainment for students from disadvantaged backgrounds is a prominent component of numerous state and federal legislation focused on higher education. In 1999, the National Science Foundation (NSF) instituted the "Computer Science, Engineering, and Mathematics Scholarships" (CSEMS) program; this initiative was designed to provide greater access and support to academically talented students from economically disadvantaged backgrounds. Originally intended to provide financial support to lower income students, this NSF program also advocated that additional professional development and advising would be strategies to increase undergraduate persistence to graduation. This innovative program for economically disadvantaged students was extended in 2004 to include students from other disciplines including the physical and life sciences as well as the technology fields, and the new name of the program was Scholarships for Science, Technology, Engineering and Mathematics (S-STEM). The implementation of these two programs in Louisiana State University (LSU) has shown significant and measurable success since 2000, making LSU a Model University in providing support to economically disadvantaged students within the STEM disciplines. The achievement of these programs is evidenced by the graduation rates of its participants. This report provides details on the educational model employed through the CSEMS/S-STEM projects at LSU and provides a path to success for increasing student retention rates in STEM disciplines. While the LSU's experience is presented as a case study, the potential relevance of this innovative mentoring program in conjunction with the financial support system is discussed in detail.

  20. A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood.

    Science.gov (United States)

    Teuffel, Pauline; Goebel-Stengel, Miriam; Hofmann, Tobias; Prinz, Philip; Scharner, Sophie; Körner, Jan L; Grötzinger, Carsten; Rose, Matthias; Klapp, Burghard F; Stengel, Andreas

    2016-04-28

    Research in the field of food intake regulation is gaining importance. This often includes the measurement of peptides regulating food intake. For the correct determination of a peptide's concentration, it should be stable during blood processing. However, this is not the case for several peptides which are quickly degraded by endogenous peptidases. Recently, we developed a blood processing method employing Reduced temperatures, Acidification, Protease inhibition, Isotopic exogenous controls and Dilution (RAPID) for the use in rats. Here, we have established this technique for the use in humans and investigated recovery, molecular form and circulating concentration of food intake regulatory hormones. The RAPID method significantly improved the recovery for (125)I-labeled somatostatin-28 (+39%), glucagon-like peptide-1 (+35%), acyl ghrelin and glucagon (+32%), insulin and kisspeptin (+29%), nesfatin-1 (+28%), leptin (+21%) and peptide YY3-36 (+19%) compared to standard processing (EDTA blood on ice, p processing, while after standard processing 62% of acyl ghrelin were degraded resulting in an earlier peak likely representing desacyl ghrelin. After RAPID processing the acyl/desacyl ghrelin ratio in blood of normal weight subjects was 1:3 compared to 1:23 following standard processing (p = 0.03). Also endogenous kisspeptin levels were higher after RAPID compared to standard processing (+99%, p = 0.02). The RAPID blood processing method can be used in humans, yields higher peptide levels and allows for assessment of the correct molecular form.

  1. Coniferous tree plantations in forest conditions-economic analysis of dedicated and semi-dedicated pathways to increase wood production

    International Nuclear Information System (INIS)

    Rakotoarison, Hanitra; Richter, Claudine; Cailly, Priscilla; Deleuze, Christine; Berthelot, Alain

    2015-01-01

    To meet growing demand for wood, particularly softwoods, the authors study a number of new silvicultural pathways for planting 3 species: Douglas fir, spruce and maritime pine. The goal of these pathways is to achieve specialised production of either industrial and workable timber, or a mixture of industrial and workable timber with medium-diameter workable timber. Pathways of this type have already been standardised for hardwoods, generally on fertile farmland. In a less fertile forest context, softwoods have a significant potential for woody production but specialized pathways and their profitability have yet to be studied. This article describes the innovative work being done to construct and simulate profitable production, new potential pathways, where plantation density, rotation time, the level of fertility are made to vary using the data from the FCBA test network in conjunction with the FCBA growth models (Oasis for spruce and Douglas fir, Sylveco for maritime pine). Economic data is derived from auction sales statistics and the ONF management and forestry work costs for the period 2012-2015. The Economics module developed by FCBA and ONF on the Capsis platform in the framework of the ICI project (Futurol) was used for the economic simulations. The analyses show that compared to conventional pathways, these pathways generally increase productivity but are nonetheless less profitable than current economic assumptions, although results vary according to species, fertility and the particular pathway. The sensitivity study shows that variations in the price of wood could alter the performance ratings as between conventional and specialised pathways. (authors)

  2. The Project Approach in Organization of Foreign Economic Activity as a Means of Increasing Competitiveness of Industrial Enterprise

    Directory of Open Access Journals (Sweden)

    Lazarenko Vladimir Ye.

    2017-12-01

    Full Text Available The article is aimed at studying the organization of foreign economic activity of industrial enterprise in case of introduction of project approach to its management. New conditions of doing business in terms of aircraft building enterprises, consisting in the transition to production according to international standards, require a modern approach to the solution of the range of issues. In conditions of limited internal financial resources of company and high expenses connected with entering the foreign market, it is extremely important to define the priority directions of foreign economic activity and the most optimal mechanisms of its organization and management. The functioning of the sphere of foreign economic activity of industrial enterprise in case of introduction of project approach to management has been analyzed. The essence, features and the main parameters of project approach as a means of increasing the competitiveness of enterprise have been defined. Priorities of the large-scale enterprise development strategy have been analyzed and suggested by means of carrying out the project method of organization of foreign economic activity.

  3. Ethanol and agriculture: Effect of increased production on crop and livestock sectors. Agricultural economic report

    International Nuclear Information System (INIS)

    House, R.; Peters, M.; Baumes, H.; Disney, W.T.

    1993-05-01

    Expanded ethanol production could increase US farm income by as much as $1 billion (1.4 percent) by 2000. Because corn is the primary feedstock for ethanol, growers in the Corn Belt would benefit most from improved ethanol technology and heightened demand. Coproducts from the conversion process (corn gluten meal, corn gluten feed, and others) compete with soybean meal, soybean growers in the South may see revenues decline. The US balance of trade would improve with increased ethanol production as oil import needs decline

  4. Economic and public health impact of 2007-2010 tobacco tax increases in Ukraine.

    Science.gov (United States)

    Ross, Hana; Stoklosa, Michal; Krasovsky, Konstantin

    2012-07-01

    To evaluate the impact of the dynamic 2007-2010 tobacco tax policy in Ukraine on cigarette prices, cigarette consumption, tobacco tax revenue and the tobacco industry's price strategy. Using data on cigarette sales, cigarette prices, income and tobacco control policies, price elasticities of cigarette demand in Ukraine were estimated using two methods. Annual data were used to generate point price elasticity estimates, while monthly data were used in a two-step Engle-Granger procedure. The point price elasticity estimate is data sensitive and ranges from -0.11 to -0.62, centring around -0.32. The regression model estimates a long-run price elasticity of -0.28. Cigarette consumption fell by 13% in 2009 and 15% in 2010 while the tax revenue increased by US$700 million and by US$500 million in 2009 and 2010, respectively, compared to the previous year. Tax increases have changed the tobacco industry's price strategy from one of shielding consumers from the impact of smaller tax hikes in 2007-2008, to one of increasing industry net-of-tax prices, after recent, larger tax increases. The higher real tobacco excise taxes of 2009 and 2010 have significantly reduced tobacco consumption in Ukraine, resulting in encouraging public health and fiscal gains. It will be important for cigarette prices/taxes to keep pace with inflation and income growth for this impact to be sustained.

  5. Increasing the technical and economic performance of wind diesel systems by including fresh water production

    DEFF Research Database (Denmark)

    Bindner, H.; Lundsager, P.

    1996-01-01

    In many remote regions of the world there is a lack of both electricity and potable water. In order to increase the standard of living and thus maintain the population both power and water have to be supplied at reasonable prices. A good option at many of these places are wind diesel systems...

  6. Economic and environmental effects of providing increased amounts of solid feed to veal calves

    NARCIS (Netherlands)

    Mollenhorst, H.; Berentsen, P.B.M.; Berends, H.; Gerrits, W.J.J.; Boer, de I.J.M.

    2016-01-01

    Traditionally, veal calves receive most of their nutrients from milk replacer (MR). Nowadays, however, solid feed (SF; i.e., concentrates and roughages) increasingly substitutes for MR. Studies have shown that providing SF reduces different types of nonnutritive oral behaviors. The objective of

  7. Going Global: The Economic and Geopolitical Effect of China’s Increasing Outward Foreign Direct Investment

    Science.gov (United States)

    2013-03-01

    Sinopec to partner with a Malaysian oil company to undercut a Chinese National Petroleum Corporation (CNPC) bid by over $60 million. Sinopec not only...invested abroad, states will enact taxation polices, trade barriers, and other measures that favor their increase in relative power.131 In summation, if

  8.  Economic growth leads to increase of obesity and associated hepatocellular carcinoma in developing countries.

    Science.gov (United States)

    Seyda Seydel, G; Kucukoglu, Ozlem; Altinbasv, Akif; Demir, O Oguz; Yilmaz, Sezai; Akkiz, Hikmet; Otan, Emrah; Sowa, Jan-Peter; Canbay, Ali

    2016-01-01

     Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and the third leading cause of cancer related death worldwide. In recent years, the prevalence of HCC has increased in both developing and developed countries. Most HCC cases develop in the presence of advanced chronic liver disease related to viral hepatitis. In particular hepatitis B virus and hepatitis C virus infections are considered as major HCC risk factors worldwide. However, current studies provide strong evidence for increasing numbers of HCC in nonalcoholic fatty liver disease (NAFLD). NAFLD represents the hepatic manifestation of metabolic syndrome which is based on obesity and insulin resistance. Epidemiologic data clearly demonstrates that NAFLD and obesity-related disorders are significant risk factors for tumor development in general and HCC in particular. As a consequence of life style changes towards higher calorie intake and less exercise, obesity and metabolic syndrome are spreading all over the world. Due to this increase in obesity and metabolic syndrome NAFLD-related HCC will become a major health care problem in the future. In conclusion, better understanding of the impact of NAFLD and obesity in the development of HCC will improve our treatment strategies of HCC and allow preventive measures.

  9. Economic evaluation of increased ethanol use from a 'general equilibrium' aspect

    International Nuclear Information System (INIS)

    Daruvala, D.

    1997-12-01

    It has been recognized that a contribution to the reduction of carbon dioxide emissions can be achieved within the transport sector by the increased use of motor alcohols such as ethanol. The production of ethanol using renewable lignocellulosic materials such as softwood rather than a starch based process is of interest as these raw materials are cheaper and available in large quantities in Sweden. However the large quantities of wood raw material required has raised the question of how an increase in demand for wood material would affect production and profitability in other sectors, particularly the forest related industries. This study contains a broad outline over the flow of wood raw material through such sectors that can be affected if a large increased production of ethanol would occur. These sectors are the forest sector, sawmill sector, pulp sector, the district heating sector and the ethanol sector were chosen because of their production or use of wood raw material. A theoretical model that could estimate these effects was developed. The model in this study is not a general equilibrium model in the traditional sense, but has been designed to measure the net welfare effects caused by an introduction of a single distortion where other sectors in the economy, where in this case the district heating and forest related industries are assumed to be the only other sectors altered as a result. The idea behind this is that a change in the price of ethanol, caused for example by a subsidy will affect not only the market for ethanol but will even have consequences on the other markets, which are interlinked through their production and consumption of wood raw material 17 refs, 4 figs, 9 tabs

  10. Modelling the correlations of e-waste quantity with economic increase.

    Science.gov (United States)

    Awasthi, Abhishek Kumar; Cucchiella, Federica; D'Adamo, Idiano; Li, Jinhui; Rosa, Paolo; Terzi, Sergio; Wei, Guoyin; Zeng, Xianlai

    2018-02-01

    Waste from Electrical and Electronic Equipment (WEEE or e-waste) is regarded as one of the fastest growing waste streams in the world and is becoming an emerging issue owing to adverse consequences on the natural environment and the human health. This research article reveals the presence of a strong linear correlation among global e-waste generation and Gross Domestic Product. The obtained results indicate that the best fit for data can be reached by comparing e-waste collected volumes and GDP PPS. More in detail, an increase of 1000 GDP PPS means an additional 0.27kg of e-waste collected and 0.22kg of e-waste reused/recycled. Furthermore, for each additional citizen, there will be an increase of 7.7kg of e-waste collected and 6.2kg of e-waste reused/recycled. The better collection of e-waste acts an important role concerning the circular economy, and it can be an advantageous approach. Therefore, e-waste could be considered as an opportunity for recycling or recovery of valuable metals (e.g., copper, gold, silver, and palladium), given their significant content in precious metals than in mineral ores. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Economic Impacts of Increased U.S. Exports of Natural Gas: An Energy System Perspective

    Directory of Open Access Journals (Sweden)

    Kemal Sarıca

    2016-05-01

    Full Text Available With the recent shale gas boom, the U.S. is expected to have very large natural gas resources. In this respect, the key question is would it be better to rely completely on free market resource allocations which would lead to large exports of natural gas or to limit natural gas exports so that more could be used in the U.S.. After accounting for the cost of liquefying the natural gas and shipping it to foreign markets, the current price difference leaves room for considerable profit to producers from exports. In addition, there is a large domestic demand for natural gas from various sectors such as electricity generation, industrial applications, and the transportation sector etc. A hybrid modeling approach has been carried out using our version of the well-known MARket ALlocation (MARKAL-Macro model to keep bottom-up model richness with macro effects to incorporate price and gross domestic product (GDP feedbacks. One of the conclusion of this study is that permitting higher natural gas export levels leads to a small reduction in GDP (0.04%–0.17%. Higher exports also increases U.S. greenhouse gas (GHG emissions and electricity prices (1.1%–7.2%. We also evaluate the impacts of natural gas exports in the presence of a Clean Energy Standard (CES for electricity. In this case, the GDP impacts are similar, but the electricity and transport sector impacts are different.

  12. A Rapid, Highly Efficient and Economical Method of Agrobacterium-Mediated In planta Transient Transformation in Living Onion Epidermis

    Science.gov (United States)

    Xu, Kedong; Huang, Xiaohui; Wu, Manman; Wang, Yan; Chang, Yunxia; Liu, Kun; Zhang, Ju; Zhang, Yi; Zhang, Fuli; Yi, Liming; Li, Tingting; Wang, Ruiyue; Tan, Guangxuan; Li, Chengwei

    2014-01-01

    Transient transformation is simpler, more efficient and economical in analyzing protein subcellular localization than stable transformation. Fluorescent fusion proteins were often used in transient transformation to follow the in vivo behavior of proteins. Onion epidermis, which has large, living and transparent cells in a monolayer, is suitable to visualize fluorescent fusion proteins. The often used transient transformation methods included particle bombardment, protoplast transfection and Agrobacterium-mediated transformation. Particle bombardment in onion epidermis was successfully established, however, it was expensive, biolistic equipment dependent and with low transformation efficiency. We developed a highly efficient in planta transient transformation method in onion epidermis by using a special agroinfiltration method, which could be fulfilled within 5 days from the pretreatment of onion bulb to the best time-point for analyzing gene expression. The transformation conditions were optimized to achieve 43.87% transformation efficiency in living onion epidermis. The developed method has advantages in cost, time-consuming, equipment dependency and transformation efficiency in contrast with those methods of particle bombardment in onion epidermal cells, protoplast transfection and Agrobacterium-mediated transient transformation in leaf epidermal cells of other plants. It will facilitate the analysis of protein subcellular localization on a large scale. PMID:24416168

  13. Testing the economic independence hypothesis: the effect of an exogenous increase in child support on subsequent marriage and cohabitation.

    Science.gov (United States)

    Cancian, Maria; Meyer, Daniel R

    2014-06-01

    We examine the effects of an increase in income on the cohabitation and marriage of single mothers. Using data from an experiment that resulted in randomly assigned differences in child support receipt for welfare-receiving single mothers, we find that exogenous income increases (as a result of receiving all child support that was paid) are associated with significantly lower cohabitation rates between mothers and men who are not the fathers of their child(ren). Overall, these results support the hypothesis that additional income increases disadvantaged women's economic independence by reducing the need to be in the least stable type of partnerships. Our results also show the potential importance of distinguishing between biological and social fathers.

  14. Integrated rice-duck farming decreases global warming potential and increases net ecosystem economic budget in central China.

    Science.gov (United States)

    Sheng, Feng; Cao, Cou-Gui; Li, Cheng-Fang

    2018-05-31

    Over the past decades, many attempts have been made to assess the effects of integrated rice-duck farming on greenhouse gas emissions, use efficient of energy, soil fertility, and economic significance. However, very few studies have been focused on the effects of the farming on net ecosystem economic budget (NEEB). Here, a 2-year field experiment was conducted to comprehensively investigate the effects of ducks raised in paddy fields on CH 4 and N 2 O emissions, global warming potential (GWP), rice grain yield, and NEEB in central China. The experiment included two treatments: integrated rice-duck farming (RD) and conventional rice farming (R). The introduction of ducks into the paddy fields markedly increased the rice grain yield due to enhanced tiller number and root bleeding rate. RD treatment significantly elevated the N 2 O emissions (p < 0.05) but decreased CH 4 emissions (p < 0.05) during rice growing seasons compared with R treatment. Analysis of GWP based on CH 4 and N 2 O emissions showed that compared with R treatment, RD treatment significantly decreased the GWP by 28.1 and 28.0% and reduced the greenhouse gas intensity by 30.6 and 29.8% in 2009 and 2010, respectively. In addition, RD treatment increased NEEB by 40.8 and 39.7% respectively in 2009 and 2010 relative to R treatment. Taken together, our results suggest that the integrated rice-duck farming system is an effective strategy to optimize the economic and environmental benefits of paddy fields in central China.

  15. Rapid increase in cosmogenic 14C in AD 775 measured in New Zealand kauri trees indicates short-lived increase in 14C production spanning both hemispheres

    Science.gov (United States)

    Güttler, D.; Adolphi, F.; Beer, J.; Bleicher, N.; Boswijk, G.; Christl, M.; Hogg, A.; Palmer, J.; Vockenhuber, C.; Wacker, L.; Wunder, J.

    2015-02-01

    In 2012, Miyake et al. reported a sudden and strong increase of the atmospheric radiocarbon (14C) content in Japanese cedar trees of 1.2% between AD 774 and 775. While their findings were quickly confirmed by a German oak chronology for the Northern Hemisphere (NH), the question remained if the effect was seen in both hemispheres. Here we present the first annually resolved Southern Hemisphere (SH) 14C record spanning the interval AD 760-787, using New Zealand kauri (Agathis australis) chronology wood. An almost identical distinct increase compared to Northern Hemisphere data was observed, suggesting a cosmic event with globally uniform impact as a potential cause for the increase. Deploying a carbon cycle box model a worldwide averaged net 14C production of 2.2 ×108 14C atoms cm-2 was estimated, which is 3.7 times higher than the average annual 14C production. The immediate appearance of the event in tree rings on both hemispheres suggests a short duration event of significantly less than 1 yr.

  16. Analysis of complete mitochondrial genome sequences increases phylogenetic resolution of bears (Ursidae, a mammalian family that experienced rapid speciation

    Directory of Open Access Journals (Sweden)

    Ryder Oliver A

    2007-10-01

    Full Text Available Abstract Background Despite the small number of ursid species, bear phylogeny has long been a focus of study due to their conservation value, as all bear genera have been classified as endangered at either the species or subspecies level. The Ursidae family represents a typical example of rapid evolutionary radiation. Previous analyses with a single mitochondrial (mt gene or a small number of mt genes either provide weak support or a large unresolved polytomy for ursids. We revisit the contentious relationships within Ursidae by analyzing complete mt genome sequences and evaluating the performance of both entire mt genomes and constituent mtDNA genes in recovering a phylogeny of extremely recent speciation events. Results This mitochondrial genome-based phylogeny provides strong evidence that the spectacled bear diverged first, while within the genus Ursus, the sloth bear is the sister taxon of all the other five ursines. The latter group is divided into the brown bear/polar bear and the two black bears/sun bear assemblages. These findings resolve the previous conflicts between trees using partial mt genes. The ability of different categories of mt protein coding genes to recover the correct phylogeny is concordant with previous analyses for taxa with deep divergence times. This study provides a robust Ursidae phylogenetic framework for future validation by additional independent evidence, and also has significant implications for assisting in the resolution of other similarly difficult phylogenetic investigations. Conclusion Identification of base composition bias and utilization of the combined data of whole mitochondrial genome sequences has allowed recovery of a strongly supported phylogeny that is upheld when using multiple alternative outgroups for the Ursidae, a mammalian family that underwent a rapid radiation since the mid- to late Pliocene. It remains to be seen if the reliability of mt genome analysis will hold up in studies of other

  17. Rapid decadal convective precipitation increase over Eurasia during the last three decades of the 20th century.

    Science.gov (United States)

    Ye, Hengchun; Fetzer, Eric J; Wong, Sun; Lambrigtsen, Bjorn H

    2017-01-01

    Convective precipitation-localized, short-lived, intense, and sometimes violent-is at the root of challenges associated with observation, simulation, and prediction of precipitation. The understanding of long-term changes in convective precipitation characteristics and their role in precipitation extremes and intensity over extratropical regions are imperative to future water resource management; however, they have been studied very little. We show that annual convective precipitation total has been increasing astonishingly fast, at a rate of 18.4%/°C, of which 16% is attributable to an increase in convective precipitation occurrence, and 2.4% is attributable to increased daily intensity based on the 35 years of two (combined) historical data sets of 3-hourly synoptic observations and daily precipitation. We also reveal that annual daily precipitation extreme has been increasing at a rate of about 7.4%/°C in convective events only. Concurrently, the overall increase in mean daily precipitation intensity is mostly due to increased convective precipitation, possibly at the expanse of nonconvective precipitation. As a result, transitional seasons are becoming more summer-like as convective becomes the dominant precipitation type that has accompanied higher daily extremes and intensity since the late 1980s. The data also demonstrate that increasing convective precipitation and daily extremes appear to be directly linearly associated with higher atmospheric water vapor accompanying a warming climate over northern Eurasia.

  18. Does plasticity in plant physiological traits explain the rapid increase in water use efficiency? An ecohydrological modeling approach

    Science.gov (United States)

    Mastrotheodoros, Theodoros; Fatichi, Simone; Pappas, Christoforos; Molnar, Peter; Burlando, Paolo

    2016-04-01

    The rise of atmospheric CO2 concentration is expected to stimulate plant productivity by enhancing photosynthesis and reducing stomatal conductance and thus increasing plant water use efficiency (WUE) worldwide. An analysis of eddy covariance flux tower data from 21 forested ecosystems across the north hemisphere detected an unexpectedly large increase in WUE (Keenan et al, 2013), which was six times larger than the increase found by most previous studies based on controlled experiments (e.g., FACE), leaf-scale analyses, and numerical modelling. This increase could be solely attributed to the increase in atmospheric CO2 since other confounding factors were ruled out. Here, we investigate the potential contribution of plant plasticity, reflected in the temporal adjustment of major plant physiological traits, on changes in WUE using the ecohydrological model Tethys and Chloris (T&C). We hypothesize that the increase in WUE can be attributed to small variations in plant physiological traits, undetectable through observations, eventually triggered by the atmospheric CO2 increase. Data from the 21 sites in the above mentioned study are used to force the model. Simulation results with and without plasticity in the physiological traits (i.e., model parameters in our numerical experiments) are compared with the observed trends in WUE. We test several plant adaptation strategies in being effective in explaining the observed increase in WUE using a multifactorial numerical experiment in which we perturb in a systematic way selected plant parameters. Keenan, T. F., Hollinger, D. Y., Bohrer, G., Dragoni, D., Munger, J. W., Schmid, H. P., and Richardson, A. D. (2013). Increase in forest water-use efficiency as atmospheric carbon dioxide concentrations rise. Nature, 499(7458), 324-7.

  19. Clickenomics: Using a Classroom Response System to Increase Student Engagement in a Large-Enrollment Principles of Economics Course

    Science.gov (United States)

    Salemi, Michael K.

    2009-01-01

    One of the most important challenges facing college instructors of economics is helping students engage. Engagement is particularly important in a large-enrollment Principles of Economics course, where it can help students achieve a long-lived understanding of how economists use basic economic ideas to look at the world. The author reports how…

  20. Did the Establishment of Poyang Lake Eco-Economic Zone Increase Agricultural Labor Productivity in Jiangxi Province, China?

    Directory of Open Access Journals (Sweden)

    Tao Wu

    2015-12-01

    Full Text Available In this paper, we take the establishment of Poyang Lake Eco-Economic Zone in 2009 as a quasi-natural experiment, to evaluate its influence on the agricultural labor productivity in Jiangxi Province, China. The estimation results of the DID method show that the establishment of the zone reduced agricultural labor productivity by 3.1%, lowering farmers’ net income by 2.5% and reducing the agricultural GDP by 3.6%. Furthermore, this negative effect has increased year after year since 2009. However, the heterogeneity analysis implies that the agricultural labor productivities of all cities in Jiangxi Province will ultimately converge. We find that the lack of agricultural R&D activities and the abuse of chemical fertilizers may be the main reasons behind the negative influence of the policy, by examining two possible transmission channels—the R&D investment and technological substitution. Corresponding policy implications are also provided.

  1. Identifying solutions to increase participation in physical activity interventions within a socio-economically disadvantaged community: a qualitative study.

    Science.gov (United States)

    Cleland, Claire L; Hunter, Ruth F; Tully, Mark A; Scott, David; Kee, Frank; Donnelly, Michael; Prior, Lindsay; Cupples, Margaret E

    2014-05-23

    There is an urgent need to increase population levels of physical activity, particularly amongst those who are socio-economically disadvantaged. Multiple factors influence physical activity behaviour but the generalisability of current evidence to such 'hard-to-reach' population subgroups is limited by difficulties in recruiting them into studies. Also, rigorous qualitative studies of lay perceptions and perceptions of community leaders about public health efforts to increase physical activity are sparse. We sought to explore, within a socio-economically disadvantaged community, residents' and community leaders' perceptions of physical activity (PA) interventions and issues regarding their implementation, in order to improve understanding of needs, expectations, and social/environmental factors relevant to future interventions. Within an ongoing regeneration project (Connswater Community Greenway), in a socio-economically disadvantaged community in Belfast, we collaborated with a Community Development Agency to purposively sample leaders from public- and voluntary-sector community groups and residents. Individual semi-structured interviews were conducted with 12 leaders. Residents (n = 113), of both genders and a range of ages (14 to 86 years) participated in focus groups (n = 14) in local facilities. Interviews and focus groups were recorded, transcribed verbatim and analysed using a thematic framework. Three main themes were identified: awareness of PA interventions; factors contributing to intervention effectiveness; and barriers to participation in PA interventions. Participants reported awareness only of interventions in which they were involved directly, highlighting a need for better communications, both inter- and intra-sectoral, and with residents. Meaningful engagement of residents in planning/organisation, tailoring to local context, supporting volunteers, providing relevant resources and an 'exit strategy' were perceived as important factors

  2. Increasing magnitude of Hurricane Rapid Intensification in the central-eastern Atlantic over the past 30 years

    Science.gov (United States)

    Leung, L. R.; Balaguru, K.; Foltz, G. R.

    2017-12-01

    During the 2017 Atlantic hurricane season, several hurricanes underwent rapid intensification (RI) in the central-eastern Atlantic. This motivates an analysis of trends in the strength of hurricane RI during the 30-year post-satellite period of 1986-2015. Our results show that in the eastern tropical Atlantic, to the east of 60W, the mean RI magnitude averaged during 2001-2015 was 3.8 kt per 24 hr higher than during 1986-2000. However, in the western tropical Atlantic, to the west of 60W, changes in RI magnitude over the same period were not statistically significant. We examined the large-scale environment to understand the causes behind these changes in RI magnitude and found that various oceanic and atmospheric parameters that play an important role in RI changed favorably in the eastern tropical Atlantic. More specifically, changes in SST, Potential Intensity, upper-ocean heat content, wind shear, relative humidity and upper-level divergence enhanced the ability for hurricanes to undergo RI in the eastern tropical Atlantic. In contrast, changes in the same factors are inconsistent in the western tropical Atlantic. While changes in SST and Potential Intensity were positive, changes in upper-ocean heat content, wind shear and upper-level divergence were either insignificant or unfavorable for RI. Finally, we examined the potential role of various climate phenomena, which are well-known to impact Atlantic hurricane activity, in causing the changes in the large-scale environment. Our analysis reveals that changes in the Atlantic Multidecadal Oscillation over the 30-year period are predominantly responsible. These results provide important aspects of the large-scale context to understand the Atlantic hurricane season of 2017.

  3. Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE): a physiological method of increasing apnoea time in patients with difficult airways.

    Science.gov (United States)

    Patel, A; Nouraei, S A R

    2015-03-01

    Emergency and difficult tracheal intubations are hazardous undertakings where successive laryngoscopy-hypoxaemia-re-oxygenation cycles can escalate to airway loss and the 'can't intubate, can't ventilate' scenario. Between 2013 and 2014, we extended the apnoea times of 25 patients with difficult airways who were undergoing general anaesthesia for hypopharyngeal or laryngotracheal surgery. This was achieved through continuous delivery of transnasal high-flow humidified oxygen, initially to provide pre-oxygenation, and continuing as post-oxygenation during intravenous induction of anaesthesia and neuromuscular blockade until a definitive airway was secured. Apnoea time commenced at administration of neuromuscular blockade and ended with commencement of jet ventilation, positive-pressure ventilation or recommencement of spontaneous ventilation. During this time, upper airway patency was maintained with jaw-thrust. Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) was used in 15 males and 10 females. Mean (SD [range]) age at treatment was 49 (15 [25-81]) years. The median (IQR [range]) Mallampati grade was 3 (2-3 [2-4]) and direct laryngoscopy grade was 3 (3-3 [2-4]). There were 12 obese patients and nine patients were stridulous. The median (IQR [range]) apnoea time was 14 (9-19 [5-65]) min. No patient experienced arterial desaturation gaseous exchange through flow-dependent deadspace flushing. It has the potential to transform the practice of anaesthesia by changing the nature of securing a definitive airway in emergency and difficult intubations from a pressured stop-start process to a smooth and unhurried undertaking. © 2014 The Authors Anaesthesia published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists of Great Britain and Ireland.

  4. Enduring increases in anxiety-like behavior and rapid nucleus accumbens dopamine signaling in socially isolated rats.

    Science.gov (United States)

    Yorgason, Jordan T; España, Rodrigo A; Konstantopoulos, Joanne K; Weiner, Jeffrey L; Jones, Sara R

    2013-03-01

    Social isolation (SI) rearing, a model of early life stress, results in profound behavioral alterations, including increased anxiety-like behavior, impaired sensorimotor gating and increased self-administration of addictive substances. These changes are accompanied by alterations in mesolimbic dopamine function, such as increased dopamine and metabolite tissue content, increased dopamine responses to cues and psychostimulants, and increased dopamine neuron burst firing. Using voltammetric techniques, we examined the effects of SI rearing on dopamine transporter activity, vesicular release and dopamine D2-type autoreceptor activity in the nucleus accumbens core. Long-Evans rats were housed in group (GH; 4/cage) or SI (1/cage) conditions from weaning into early adulthood [postnatal day (PD) 28-77]. After this initial housing period, rats were assessed on the elevated plus-maze for an anxiety-like phenotype, and then slice voltammetry experiments were performed. To study the enduring effects of SI rearing on anxiety-like behavior and dopamine terminal function, another cohort of similarly reared rats was isolated for an additional 4 months (until PD 174) and then tested. Our findings demonstrate that SI rearing results in lasting increases in anxiety-like behavior, dopamine release and dopamine transporter activity, but not D2 activity. Interestingly, GH-reared rats that were isolated as adults did not develop the anxiety-like behavior or dopamine changes seen in SI-reared rats. Together, our data suggest that early life stress results in an anxiety-like phenotype, with lasting increases in dopamine terminal function. © 2013 Federation of European Neuroscience Societies and Blackwell Publishing Ltd.

  5. Rapid Increases in forest understory diversity and productivity following a mountain pine beetle (Dendroctonus ponderosae outbreak in pine forests.

    Directory of Open Access Journals (Sweden)

    Gregory J Pec

    Full Text Available The current unprecedented outbreak of mountain pine beetle (Dendroctonus ponderosae in lodgepole pine (Pinus contorta forests of western Canada has resulted in a landscape consisting of a mosaic of forest stands at different stages of mortality. Within forest stands, understory communities are the reservoir of the majority of plant species diversity and influence the composition of future forests in response to disturbance. Although changes to stand composition following beetle outbreaks are well documented, information on immediate responses of forest understory plant communities is limited. The objective of this study was to examine the effects of D. ponderosae-induced tree mortality on initial changes in diversity and productivity of understory plant communities. We established a total of 110 1-m2 plots across eleven mature lodgepole pine forests to measure changes in understory diversity and productivity as a function of tree mortality and below ground resource availability across multiple years. Overall, understory community diversity and productivity increased across the gradient of increased tree mortality. Richness of herbaceous perennials increased with tree mortality as well as soil moisture and nutrient levels. In contrast, the diversity of woody perennials did not change across the gradient of tree mortality. Understory vegetation, namely herbaceous perennials, showed an immediate response to improved growing conditions caused by increases in tree mortality. How this increased pulse in understory richness and productivity affects future forest trajectories in a novel system is unknown.

  6. Rapid Increases in forest understory diversity and productivity following a mountain pine beetle (Dendroctonus ponderosae) outbreak in pine forests.

    Science.gov (United States)

    Pec, Gregory J; Karst, Justine; Sywenky, Alexandra N; Cigan, Paul W; Erbilgin, Nadir; Simard, Suzanne W; Cahill, James F

    2015-01-01

    The current unprecedented outbreak of mountain pine beetle (Dendroctonus ponderosae) in lodgepole pine (Pinus contorta) forests of western Canada has resulted in a landscape consisting of a mosaic of forest stands at different stages of mortality. Within forest stands, understory communities are the reservoir of the majority of plant species diversity and influence the composition of future forests in response to disturbance. Although changes to stand composition following beetle outbreaks are well documented, information on immediate responses of forest understory plant communities is limited. The objective of this study was to examine the effects of D. ponderosae-induced tree mortality on initial changes in diversity and productivity of understory plant communities. We established a total of 110 1-m2 plots across eleven mature lodgepole pine forests to measure changes in understory diversity and productivity as a function of tree mortality and below ground resource availability across multiple years. Overall, understory community diversity and productivity increased across the gradient of increased tree mortality. Richness of herbaceous perennials increased with tree mortality as well as soil moisture and nutrient levels. In contrast, the diversity of woody perennials did not change across the gradient of tree mortality. Understory vegetation, namely herbaceous perennials, showed an immediate response to improved growing conditions caused by increases in tree mortality. How this increased pulse in understory richness and productivity affects future forest trajectories in a novel system is unknown.

  7. Implications for U.S. trade and nonindigenous species risk resulting from increased economic integration of the Asia-Pacific Region

    Science.gov (United States)

    Amanda M. Countryman; Travis Warziniack; Erin Grey

    2018-01-01

    This work investigates how potential changes in trade patterns resulting from increased economic integration in the Asia-Pacific region may affect the risk for nonindigenous species spread to the United States. We construct an invasion risk index utilizing the results from a global economic modeling framework in tandem with data for climate similarities between trade...

  8. Energy system, electricity market and economic studies on increasing nuclear power capacity; Ydinvoimahankkeiden periaatepaeaetoekseen liittyvaet energia- ja kansantaloudelliset selvitykset

    Energy Technology Data Exchange (ETDEWEB)

    Forsstrom, J.; Pursiheimo, E.; Kekkonen, V.; Honkatukia, J.

    2010-04-15

    Objective of this research project is to examine effects of addition of nuclear capacity from three different angles by using energy system, electricity market and economic analysis. In each area the analysis is based on computational methods. Finland is a member of Nordic electricity market which is further connected to networks of Continental Europe and Russia. Due to the foreign connections Finland has been able to import inexpensive electricity from its neighboring countries and this state is expected to continue. Addition of nuclear capacity lowers electricity import demand, affects level of electricity price decreasingly and decreases shortfall of installed production capacity. Substantial additions of nuclear power capacity and generous import supply have disadvantageous effect on profitability of combined heat and power production. The development of import possibilities depends on progression of difficult-to-estimate balance between electricity consumption and production in the neighboring countries. Investments on nuclear power increase national product during the construction phase. Growth of employment is also rather significant, especially during the construction phase. In the long term permanent jobs will be created too. Increase of employment is held back by increasing real wages, but it is though evident that consumer purchasing power is improved due to these nuclear power developments. (orig.)

  9. Post-Mesozoic Rapid Increase of Seawater Mg/Ca due to Enhanced Mantle-Seawater Interaction

    OpenAIRE

    Marco Ligi; Enrico Bonatti; Marco Cuffaro; Daniele Brunelli

    2013-01-01

    The seawater Mg/Ca ratio increased significantly from ~ 80?Ma to present, as suggested by studies of carbonate veins in oceanic basalts and of fluid inclusions in halite. We show here that reactions of mantle-derived peridotites with seawater along slow spreading mid-ocean ridges contributed to the post-Cretaceous Mg/Ca increase. These reactions can release to modern seawater up to 20% of the yearly Mg river input. However, no significant peridotite-seawater interaction and Mg-release to the ...

  10. Impaired gait function in adults with cerebral palsy is associated with reduced rapid force generation and increased passive stiffness

    DEFF Research Database (Denmark)

    Geertsen, Svend Sparre; Kirk, Henrik; Lorentzen, Jakob

    2015-01-01

    analysis of the ankle joint during treadmill walking was obtained by 3-D motion analysis. RESULTS: Passive stiffness was significantly increased in adults with CP compared to controls. Passive stiffness and RFDdf were correlated to reduced toe lift. RFDpf provided the best correlation to push-off velocity...

  11. Characterization of apoplast phenolics: Invitro oxidation of acetosyringone results in a rapid prolonged increase in the redox potential

    Science.gov (United States)

    In a previous study we observed that if tobacco cell suspensions were inoculated with certain bacterial strains, several hours later the redox potential of the suspensions would increase (oxidative), as much as 100 mV, and in some cases last more than an hour. To discover possible contributors to t...

  12. Rapid increase in lymphogranuloma venereum in men who have sex with men, United Kingdom, 2003 to September 2015.

    Science.gov (United States)

    Childs, Tristan; Simms, Ian; Alexander, Sarah; Eastick, Kirstine; Hughes, Gwenda; Field, Nigel

    2015-01-01

    United Kingdom (UK) national data show a sharp increase in diagnoses of lymphogranuloma venereum (LGV) since 2012. Most cases are in men who have sex with men (MSM) living in London, with high rates of co-infection with HIV and other sexually transmitted infections. In light of these data, and the recent finding that one quarter of LGV infections may be asymptomatic, clinicians should be vigilant in testing for LGV, including in asymptomatic HIV-positive MSM.

  13. Post-Mesozoic Rapid Increase of Seawater Mg/Ca due to Enhanced Mantle-Seawater Interaction

    Science.gov (United States)

    Ligi, Marco; Bonatti, Enrico; Cuffaro, Marco; Brunelli, Daniele

    2013-01-01

    The seawater Mg/Ca ratio increased significantly from ~ 80 Ma to present, as suggested by studies of carbonate veins in oceanic basalts and of fluid inclusions in halite. We show here that reactions of mantle-derived peridotites with seawater along slow spreading mid-ocean ridges contributed to the post-Cretaceous Mg/Ca increase. These reactions can release to modern seawater up to 20% of the yearly Mg river input. However, no significant peridotite-seawater interaction and Mg-release to the ocean occur in fast spreading, East Pacific Rise-type ridges. The Mesozoic Pangean superocean implies a hot fast spreading ridge system. This prevented peridotite-seawater interaction and Mg release to the Mesozoic ocean, but favored hydrothermal Mg capture and Ca release by the basaltic crust, resulting in a low seawater Mg/Ca ratio. Continent dispersal and development of slow spreading ridges allowed Mg release to the ocean by peridotite-seawater reactions, contributing to the increase of the Mg/Ca ratio of post-Mesozoic seawater. PMID:24067442

  14. Loads of green washing—can behavioural economics increase willingness-to-pay for efficient washing machines in the UK?

    International Nuclear Information System (INIS)

    Bull, Joe

    2012-01-01

    The EU energy efficiency labelling scheme has successfully increased demand for efficient appliances by providing a prominent letter rating to consumers during their product search. Behavioural economics (BE) suggests the adoption of efficient appliances could be accelerated further by: (i) monetising efficiency, (ii) directly communicating the link between efficiency and carbon emissions, (iii) communicating the long-term (e.g., operational life) financial and environmental impact of product choices, and, (iv) framing the information as avoided losses (‘extra’) rather than gains (‘savings’). This study tested these hypotheses via an online, stated preference survey of 465 UK residents using actual market pricing and efficiency data for washing machines. The provision of information about either running costs or running emissions did encourage selection of more expensive and efficient products (strongly correlated variables in the choice set and actual market) (p<.001, r=.30–.41) with no statistically significant difference between their impact. Providing lifetime running cost information also nudged respondents towards more expensive, efficient products than annual information (p=.006–.027, r=.15–.18). Finally, loss-framed running emissions information encouraged selection of more expensive, efficient products than gain-framed information (p<.05, r=.13–.16). The EU label is an impracticable means of communication, but digital communication channels (e.g., price comparison websites) may offer potential for inexpensive localisation and personalisation of the information. The results suggest that successful communication could benefit the private sector whilst making a contribution to reducing carbon emissions. - Highlights: ► 465 UK residents made a hypothetical washing machine purchase via an online survey. ► Respondents were exposed to either running cost or running emissions information. ► Running cost information increased willingness

  15. Sewage sludge and wastewater fertilisation of Short Rotation Coppice (SRC) for increased bioenergy production - Biological and economic potential

    International Nuclear Information System (INIS)

    Dimitriou, I.; Rosenqvist, H.

    2011-01-01

    Application of municipal residues, e.g. wastewater or sewage sludge, to Short Rotation Coppice (SRC) is among the most attractive methods for attaining environmental and energy goals set for Europe. At current woodchip prices in Sweden, the gross margin for SRC cultivation is positive only if biomass production is >9 t DM/ha yr. The gross profit margin increases (by 39 and 199 EUR/GJ, respectively) if sewage sludge and wastewater are applied to SRC. Application of residues to SRC has proved to be an acceptable alternative treatment method, and the farmer's profit can be markedly increased if compensation is paid for waste treatment. If all available sludge and wastewater were applied to SRC plantations, they could be grown on large agricultural areas in Europe, and c. 6000 PJ of renewable energy could be produced annually. However, a more economical landuse strategy, e.g. the use of more P-rich residues, appears more rational, and is biologically justifiable. (author)

  16. Sewage sludge and wastewater fertilisation of Short Rotation Coppice (SRC) for increased bioenergy production - Biological and economic potential

    Energy Technology Data Exchange (ETDEWEB)

    Dimitriou, I. [Department of Crop Production Ecology, Swedish University of Agricultural Sciences, P.O. Box 7043, SE 750 07 Uppsala (Sweden); Rosenqvist, H. [Department of Agriculture-Farming Systems, Technology and Product Quality, Swedish University of Agricultural Sciences, P.O. Box 17, SE-261 21 Billeberga (Sweden)

    2011-02-15

    Application of municipal residues, e.g. wastewater or sewage sludge, to Short Rotation Coppice (SRC) is among the most attractive methods for attaining environmental and energy goals set for Europe. At current woodchip prices in Sweden, the gross margin for SRC cultivation is positive only if biomass production is >9 t DM/ha yr. The gross profit margin increases (by 39 and 199 EUR/GJ, respectively) if sewage sludge and wastewater are applied to SRC. Application of residues to SRC has proved to be an acceptable alternative treatment method, and the farmer's profit can be markedly increased if compensation is paid for waste treatment. If all available sludge and wastewater were applied to SRC plantations, they could be grown on large agricultural areas in Europe, and c. 6000 PJ of renewable energy could be produced annually. However, a more economical landuse strategy, e.g. the use of more P-rich residues, appears more rational, and is biologically justifiable. (author)

  17. Trends in the incidence of nonmelanoma skin cancer in Denmark 1978-2007: Rapid incidence increase among young Danish women

    DEFF Research Database (Denmark)

    Birch-Johansen, Fatima; Jensen, Allan; Mortensen, Lone

    2010-01-01

    Nonmelanoma skin cancer (NMSC) is the most common cancer among Caucasian populations worldwide, and incidence rates are increasing. However, NMSC data are not routinely collected by cancer registries, but Denmark has extensive registration of NMSC in two nationwide population-based registries. We...... assessed incidence trends of NMSC in Denmark from 1978 to 2007. Data for basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) were obtained from the Danish Cancer Registry and the Danish Registry of Pathology. For both genders, age-specific incidence rates and overall incidence rates, age...

  18. Rapid increase of inositol 1,4,5-trisphosphate in the HeLa cells after hypergravity exposure

    Science.gov (United States)

    Kumei, Yasuhiro; Whitson, Peggy A.; Cintron, Nitza M.; Sato, Atsushige

    1990-01-01

    The IP3 level in HeLa cells has been elevated through the application in hypergravity in a time-dependent manner. The data obtained for the hydrolytic products of PIP2, IP3, and DG are noted to modulate c-myc gene expression. It is also established that the cAMP accumulation by the IBMX in hypergravity-exposed cells was suppressed relative to the control. In light of IP3 increase and cAMP decrease results, a single GTP-binding protein may play a role in the hypergravity signal transduction of HeLa cells by stimulating PLC while inhibiting adenylate cyclase.

  19. Alcohol consumption in Polish middle and high school pupils – has this rapidly increased during 2009–11?

    Directory of Open Access Journals (Sweden)

    Paulina Wojtyła-Buciora

    2014-09-01

    Full Text Available [b]Introduction.[/b] The dynamic rise of alcohol consumption in adolescents is a matter of serious concern, requiring frequently updated monitoring. By such means, it is possible to optimise preventative measures for dealing with this problem. [b]Objective[/b]. To estimate the magnitude/amount and frequency of alcohol consumed by middle and high school pupils in Poland, including the circumstances when alcohol was first drunk. [b]Materials and Methods[/b]. A randomised survey was performed throughout Poland on middle school (junior high school pupils, (n=9360 in 2009, followed by both middle and high school pupils in 2011 (n=7971. The questionnaire was devised by the Polish Chief Sanitary Inspectorate (GIS. [b]Results[/b]. A strikingly sharp increase in alcohol consumption (29% was observed in subjects between 2009 – 2011. In the latter year, 1 month prior to survey, respectively, 50% and 71% of middle school and high school pupils drank alcohol, and correspondingly, 36% and 63% of these pupils ever became intoxicated/drunk. [b]Conclusions[/b]. 1 Adolescent alcohol consumption increases with age and is highest in girls. Monitoring as well as in-depth analysis thus becomes necessary. 2 Systematic monitoring and analysis of changing healthy lifestyle behaviour should be used for taking the necessary corrective action. This should happen concurrently and consist of planned health education programmes, including health promotion.

  20. Rapid increases in permeability and porosity of bentonite-sand mixtures due to alteration by water vapor

    International Nuclear Information System (INIS)

    Couture, R.A.

    1984-01-01

    Packed columns of canister packing material containing 25% bentonite and 75% quartz or basalt sand, were exposed to water vapor at temperatures up t 260 0 C. The permeabilities of the columns were subsequently measured after complete saturation with liquid water in a pressurized system. Exposure to water vapor caused irreversible increases in permeability by factors of up to 10 5 . After saturation with liquid water, the permeability was nearly independent of temperature. The increases in permeability were due to a large decrease in the ability of the bentonite to swell in water. Calculations suggest that swelling of bentonite altered at 250 0 C was not sufficient to fill the pore spaces. If the pore spaces are filled, the mixture will form an effective barrier against flow, diffusion, and transport of colloids. The results suggest that if bentonite-based canister packing material is exposed even briefly to water vapor at high temperatures in a high-level nuclear waste repository, its performance will be seriously impaired. The problem is less severe if the proportion of bentonite is high and the material is highly compacted. Previous results show significant degradation of bentonite by water vapor at temperatures as low as 150 0 C. This suggests that in some repositories, backfill in tunnels and drifts may also be affected. 9 references, 5 figures, 1 table

  1. INCREASED COMPETITIVENESS OF CONSTRUCTION ENTERPRISES ON THE BASIS OF ORGANISATIONAL-ECONOMIC DECISIONS OF PERSONNEL POTENTIAL MANAGEMENT

    Directory of Open Access Journals (Sweden)

    J. R. Emirbekova

    2017-01-01

    Full Text Available Objectives. The development of an algorithm for optimising the formation and use of human resources of a construction enterprise.Methods. The research basis consists in a generalised methodology  for personnel management, as well as specific methods for logical  and statistical analysis of management decision-making in  construction activities. The approaches, criteria, indicators and methods for assessing the effectiveness of human resource  management are studied alongside factors influencing the efficiency  resource potential management in a construction enterprise.Results. A quantitative methodology for the selection of qualified  staff for the implementation of construction projects is proposed.  The indicators of the effectiveness of the staff potential are  determined. Qualitative and quantitative data for the optimal  personnel formation for the construction project realisation are  systematised. An algorithm for optimising the personnel potential of  a construction enterprise is proposed. The use of this algorithm will  inform the choice of organisational and economic solutions for the  formation and effective use of qualified personnel at the expense of  combining professions, thereby reducing the cost and duration of construction work and increasing the resource efficiency and competitiveness of the construction enterprise.Conclusion. The labour potential of a construction enterprise can  significantly contribute to increased efficiency if it is used  appropriately and in an organised manner, using modern scientific  methods of management. Methods for building and organising the  activity of the personnel management system are proposed and a  mechanism for establishing relationships between the employer and employees that promote the most effective use of all types of resources for the development of the enterprise according to  strategic objectives is disclosed. The dominant role of the

  2. A Boom for Whom? Exploring the Impacts of a Rapid Increase in the Male Population Upon Women's Services in Darwin, Northern Territory.

    Science.gov (United States)

    Ennis, Gretchen; Tofa, Matalena; Finlayson, Mary; U'Ren, Julie

    2016-05-03

    A rapidly expanding natural-resource extraction industry and a growing military presence mean an increasingly male-skewed population for the city of Darwin, Australia. This has sparked concerns about the potential for increased violence against women. In this article, we present qualitative research detailing the views of 13 participants from 10 women's support services in the Darwin area. We argue that women's support services bear witness to and are tasked with responding to the impacts of population change on women, yet their work is undermined by uncertainties that stem from neoliberal funding rationales and limited demands on companies to address social issues. © The Author(s) 2016.

  3. A rapid culture system uninfluenced by an inoculum effect increases reliability and convenience for drug susceptibility testing of Mycobacterium tuberculosis.

    Science.gov (United States)

    Jung, Yong-Gyun; Kim, Hyejin; Lee, Sangyeop; Kim, Suyeoun; Jo, EunJi; Kim, Eun-Geun; Choi, Jungil; Kim, Hyun Jung; Yoo, Jungheon; Lee, Hye-Jeong; Kim, Haeun; Jung, Hyunju; Ryoo, Sungweon; Kwon, Sunghoon

    2018-06-05

    The Disc Agarose Channel (DAC) system utilizes microfluidics and imaging technologies and is fully automated and capable of tracking single cell growth to produce Mycobacterium tuberculosis (MTB) drug susceptibility testing (DST) results within 3~7 days. In particular, this system can be easily used to perform DSTs without the fastidious preparation of the inoculum of MTB cells. Inoculum effect is one of the major problems that causes DST errors. The DAC system was not influenced by the inoculum effect and produced reliable DST results. In this system, the minimum inhibitory concentration (MIC) values of the first-line drugs were consistent regardless of inoculum sizes ranging from ~10 3 to ~10 8 CFU/mL. The consistent MIC results enabled us to determine the critical concentrations for 12 anti-tuberculosis drugs. Based on the determined critical concentrations, further DSTs were performed with 254 MTB clinical isolates without measuring an inoculum size. There were high agreement rates (96.3%) between the DAC system and the absolute concentration method using Löwenstein-Jensen medium. According to these results, the DAC system is the first DST system that is not affected by the inoculum effect. It can thus increase reliability and convenience for DST of MTB. We expect that this system will be a potential substitute for conventional DST systems.

  4. Rapid Increase in Genome Size as a Consequence of Transposable Element Hyperactivity in Wood-White (Leptidea) Butterflies.

    Science.gov (United States)

    Talla, Venkat; Suh, Alexander; Kalsoom, Faheema; Dinca, Vlad; Vila, Roger; Friberg, Magne; Wiklund, Christer; Backström, Niclas

    2017-10-01

    Characterizing and quantifying genome size variation among organisms and understanding if genome size evolves as a consequence of adaptive or stochastic processes have been long-standing goals in evolutionary biology. Here, we investigate genome size variation and association with transposable elements (TEs) across lepidopteran lineages using a novel genome assembly of the common wood-white (Leptidea sinapis) and population re-sequencing data from both L. sinapis and the closely related L. reali and L. juvernica together with 12 previously available lepidopteran genome assemblies. A phylogenetic analysis confirms established relationships among species, but identifies previously unknown intraspecific structure within Leptidea lineages. The genome assembly of L. sinapis is one of the largest of any lepidopteran taxon so far (643 Mb) and genome size is correlated with abundance of TEs, both in Lepidoptera in general and within Leptidea where L. juvernica from Kazakhstan has considerably larger genome size than any other Leptidea population. Specific TE subclasses have been active in different Lepidoptera lineages with a pronounced expansion of predominantly LINEs, DNA elements, and unclassified TEs in the Leptidea lineage after the split from other Pieridae. The rate of genome expansion in Leptidea in general has been in the range of four Mb/Million year (My), with an increase in a particular L. juvernica population to 72 Mb/My. The considerable differences in accumulation rates of specific TE classes in different lineages indicate that TE activity plays a major role in genome size evolution in butterflies and moths. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  5. Rapid extirpation of a North American frog coincides with an increase in fungal pathogen prevalence: Historical analysis and implications for reintroduction.

    Science.gov (United States)

    Adams, Andrea J; Pessier, Allan P; Briggs, Cheryl J

    2017-12-01

    As extinctions continue across the globe, conservation biologists are turning to species reintroduction programs as one optimistic tool for addressing the biodiversity crisis. For repatriation to become a viable strategy, fundamental prerequisites include determining the causes of declines and assessing whether the causes persist in the environment. Invasive species-especially pathogens-are an increasingly significant factor contributing to biodiversity loss. We hypothesized that Batrachochytrium dendrobatidis (Bd), the causative agent of the deadly amphibian disease chytridiomycosis, was important in the rapid (herpetological experts, analysis of archived field notes and museum specimen collections, and field sampling of the extant amphibian assemblage to examine (1) historical relative abundance of R. boylii ; (2) potential causes of R. boylii declines; and (3) historical and contemporary prevalence of Bd. We found that R. boylii were relatively abundant prior to their rapid extirpation, and an increase in Bd prevalence coincided with R. boylii declines during a time of rapid change in the region, wherein backcountry recreation, urban development, and the amphibian pet trade were all on the rise. In addition, extreme flooding during the winter of 1969 coincided with localized extirpations in R. boylii populations observed by interview respondents. We conclude that Bd likely played an important role in the rapid extirpation of R. boylii from southern California and that multiple natural and anthropogenic factors may have worked in concert to make this possible in a relatively short period of time. This study emphasizes the importance of recognizing historical ecological contexts in making future management and reintroduction decisions.

  6. The role of research programs and commercial contracts for increase of economic competitiveness and development at INR Pitesti

    International Nuclear Information System (INIS)

    Petra, Nicoleta Mihaela; Ionila, Maria; Datcu, Mirela; Balan, Iosif Bogdan; Cretu, Ileana

    2008-01-01

    In the period in which globalization is increasing, one of the strategic objectives of the institute is to focus on those activities which help developing of services, products and technologies, applicable in nuclear industry, environment protection and medicine. One way to sustain INR activity is the technological transfer which ensures availability of research results by carrying out of R and D contracts in priority areas and of contracts with economical agents for the supply of services, products, technologies, such as: - Materials irradiation for medicine, industry and research; - Neutron Activation Analysis (NAA) and prompt gamma spectrometry for Cernavoda NPP - Unit 1; - Control and testing: non-destructive examination, functional tests of samples and equipment from Cernavoda NPP - Unit 1; - Characterization, conditioning and treatment of radioactive wastes for NPP- Cernavoda, Unit 1, Nuclear Fuel Plant (FCN) - Pitesti; - Measurement of isotopes concentration in environmental samples; -Corrosion experiments in static autoclaves and experiments regarding microbial corrosion for NPP Cernavoda Unit 1 and FCN Pitesti; - Nuclear consultancy for Cernavoda NPP - Unit 1 and Unit 2; - Stainless steel casks for radwaste; - Containers for heavy water; - Training and practice for students at the Universities of Pitesti, Bucuresti, Brasov. The paper presents the main areas where the results obtained in R and D programs can be applied, their implementation can be done, and the status of contracts and their importance for INR Pitesti and Romanian society development, as well. (authors)

  7. Using Behavioral Economic Theory to Increase Use of Effective Contraceptives among Opioid-maintained Women at Risk of Unintended Pregnancy

    Science.gov (United States)

    Heil, Sarah H.; Hand, Dennis J.; Sigmon, Stacey C.; Badger, Gary J.; Meyer, Marjorie C.; Higgins, Stephen T.

    2016-01-01

    Objective An unsettling aspect of the US opioid epidemic is the high rate of in utero exposure, especially since most of these pregnancies are unintended, due in part to low rates of effective contraceptive use among opioid-using women. This study tested an intervention informed by behavioral economic theory and aimed at promoting effective contraceptive use among opioid-maintained women at risk of unintended pregnancy in the Burlington, VT area between 2011–2013. Methods Thirty-one women were assigned (initial 5 consecutively, subsequent 26 randomly) to either usual care or an experimental intervention. Participants in usual care received condoms, a dose of emergency contraception, and referral to local providers. Participants in the experimental condition received usual care plus the World Health Organization’s contraception initiation protocol, including free prescription contraceptives, and financial incentives for attending 13 follow-up visits over 6 months to help manage side effects and other issues. Results Significantly more women in the experimental vs. usual care control conditions initiated prescription contraceptive use (100% vs. 29%) and reported prescription contraceptive use at 1-month (63% vs. 13%), 3-month (88% vs. 20%), and 6-month (94% vs. 13%) assessments. None of the experimental condition participants became pregnant during the 6-month protocol vs. three women (20%) in the control condition. Conclusions These results provide the first experimental evidence supporting the efficacy of an intervention for increasing prescription contraceptive use among opioid-maintained women at risk of unintended pregnancy. PMID:27346756

  8. The problem of economic stability and the independence of Latin America in the context of the increase of military equipment

    Directory of Open Access Journals (Sweden)

    Korchun V. S.

    2015-05-01

    Full Text Available The article is based on the issue of economic stability in Latin America. Indicated that the economic potential of the countries of the region is not in plentitude. Emphasized the immediate leaders of the region, concerning the accumulation of weapons, and also shows the amount of the cost of the purchase. Also ascertained the dependence of less developed countries from the United States.

  9. Exposure to high hydrostatic pressure rapidly selects for increased RpoS activity and general stress-resistance in Escherichia coli O157:H7.

    Science.gov (United States)

    Vanlint, Dietrich; Rutten, Nele; Govers, Sander K; Michiels, Chris W; Aertsen, Abram

    2013-04-15

    Exposure to high hydrostatic pressure (HHP) is increasingly being used in food preservation as a non-thermal pasteurization process, and its further implementation necessitates a more thorough understanding of bacterial resistance development and intraspecies variability with regard to inactivation by HHP. In this report, we discovered that exposure to high hydrostatic pressure stress can rapidly select for strongly increased RpoS activity in a hypersensitive Escherichia coli O157:H7 strain (ATCC 43888), leading to a simultaneous increase in HHP and heat resistance. Moreover, the level of RpoS activity correlated well with the original hypersensitivity and the extent of acquired HHP resistance, and extremely HHP-resistant mutants of ATCC 43888 clearly incurred a number of additional RpoS-dependent phenotypes. These findings suggest that implementation of novel processing techniques in the food production chain can readily affect the physiology of food-borne pathogens. Copyright © 2013 Elsevier B.V. All rights reserved.

  10. Quantum economics

    Directory of Open Access Journals (Sweden)

    Vukotić Veselin

    2011-01-01

    Full Text Available The globalization is breaking-down the idea of national state, which was the base for the development of economic theory which is dominant today. Global economic crisis puts emphasis on limited possibilities of national governments in solving economic problems and general problems of society. Does it also mean that globalization and global economic crisis points out the need to think about new economic theory and new understanding of economics? In this paper I will argue that globalization reveals the need to change dominant economic paradigm - from traditional economic theory (mainstream with macroeconomic stability as the goal of economic policy, to the “quantum economics“, which is based on “economic quantum” and immanent to the increase of wealth (material and non-material of every individual in society and promoting set of values immanent to the wealth increase as the goal of economic policy. Practically the question is how we can use global market for our development!

  11. Economic impacts of an increase in the foreign tourism receipts: A sam-based income multiplier analysis for Turkey

    Directory of Open Access Journals (Sweden)

    Hasan Gül

    2013-12-01

    Full Text Available This   study   aims   at   analyzing   the   impacts   of   an   increase   in   inbound   tourism  receipts   in   Turkey.   To   carry   out   the   analyses   a   social   accounting   matrix   is   developed,  that  explicitly  included  tourism  as  an  aggregate  industry,  by  basing  on  input-­output  and  tourism  satellite  account  tables.  Income  multipliers  derived  from  this   social   accounting   matrix   are   used   to   reveal   the   effects   on   inter-­industry  relations,   factor   and  household  incomes.  Empirical   findings   suggest   that  demand  side  shocks  on  tourism  industry  might  be  used  to  boost  the  overall  economy  and  to  cope  with  unemployment  problem.  In  addition,  the  economic  potential  involved  in  tourism  industry  seems   to  be  promising  in   terms  of  reaching   the  intended   targets   declared  in  “Tourism  Strategy  of  Turkey-­2023”.

  12. Environmental, economic, social and political drivers for increasing use of woodfuel as a renewable resource in Britain

    International Nuclear Information System (INIS)

    McKay, Helen

    2006-01-01

    Present woodfuel usage in Britain is negligible. Historically, Britain has been fortunate in having abundant coal, oil and gas. At an EU level, biomass is seen as an important element of energy, environment and agriculture/forestry policy. In the European context, biomass is taken to include agricultural and industrial wastes in addition to forest woodfuel, and it is regarded as a potential source of heat, fuels and electricity. In the UK, energy policy as a whole is based on four considerations-environment, energy reliability and security, affordability for the poorest in society and competitive pricing for businesses, industries and households. Within UK policy, the dominant driver for greater use of biomass as a renewable source of energy is climate change mitigation; energy security is an emerging driver; all other potential benefits of biomass as a renewable resource are of limited significance. At the moment, the UK focus is narrower than in Europe. National targets are set only for electricity generation. Furthermore, expansion of energy crops, which are defined in the major regulations as 'crops planted since 1989 and grown primarily for the purpose of being used as a fuel' and, therefore, do not include material from extant forests, is seen as the main way to ensure energy security and minimise carbon expended to transport the raw material to the point of end use. Nevertheless, woody biomass from forests, sawmills, urban areas and transportation corridors is already available in vastly greater quantities than 'energy crops'. At a regional and local scale, global environmental issues are of lower relative importance and a much wider range of potential benefits tend to be taken into consideration. For example, the economic benefits of woodfuel heating in areas without connections to the gas grid have been an important consideration in the steady increase in woodheat developments. In other areas where there is a less obvious financial driver, rural

  13. Development of mechanisms and instruments of increasing economic safety with regard to the peculiarities of the present stage of the economy

    Directory of Open Access Journals (Sweden)

    Yu. M. Sokolinskaya

    2017-01-01

    Full Text Available The development of theoretical provisions of economic security, their mechanisms and instruments is determined by the laws of the economy that reveal the management of production, the market processes of distribution, exchange, consumption, taking into account the features of industries, regions, the level of globalization, etc. Each sphere, region or branch of the economy is characterized by peculiar economic processes justified by a specific approach to their disclosure. Economic security, its emergence, development and adaptation to changing market conditions, is based on the information economy or on the knowledge economy. Economic security is determined by the costs of information, its confidentiality, taking into account the interaction, on the one hand, and the competition of various enterprises, regions and countries, on the other. In the process of economic development, knowledge in general and any specialists are needed, but only those that are necessary in the economy. Communication and interaction of science, knowledge, information with production provides not only economic security, but also their successful development. To develop certain principles or laws for the interaction of technological and economic factors, their degree and level of interaction, a study of economic activity was conducted. In the present study, a civilizational approach was used that is based on the determining role of man in the economy and society and the importance of knowledge and information, when the important mechanisms remain: the development of technology and technology, the role of knowledge and information, and communication. The implementation of the civilized approach takes into account the new methodological level of increasing economic security, when the main factor in the development of the economy is the scientific and technological progress that justifies the information path of economic development.

  14. Polymeric nanoparticles for increased oral bioavailability and rapid absorption using celecoxib as a model of a low-solubility, high-permeability drug.

    Science.gov (United States)

    Morgen, Michael; Bloom, Corey; Beyerinck, Ron; Bello, Akintunde; Song, Wei; Wilkinson, Karen; Steenwyk, Rick; Shamblin, Sheri

    2012-02-01

    To demonstrate drug/polymer nanoparticles can increase the rate and extent of oral absorption of a low-solubility, high-permeability drug. Amorphous drug/polymer nanoparticles containing celecoxib were prepared using ethyl cellulose and either sodium caseinate or bile salt. Nanoparticles were characterized using dynamic light scattering, transmission and scanning electron microscopy, and differential scanning calorimetry. Drug release and resuspension studies were performed using high-performance liquid chromatography. Pharmacokinetic studies were performed in dogs and humans. A physical model is presented describing the nanoparticle state of matter and release performance. Nanoparticles dosed orally in aqueous suspensions provided higher systemic exposure and faster attainment of peak plasma concentrations than commercial capsules, with median time to maximum drug concentration (Tmax) of 0.75 h in humans for nanoparticles vs. 3 h for commercial capsules. Nanoparticles released celecoxib rapidly and provided higher dissolved-drug concentrations than micronized crystalline drug. Nanoparticle suspensions are stable for several days and can be spray-dried to form dry powders that resuspend in water. Drug/polymer nanoparticles are well suited for providing rapid oral absorption and increased bioavailability of BCS Class II drugs.

  15. A Comprehensive Partnership Approach Increasing High School Graduation Rates and College Enrollment of Urban Economically Disadvantaged Youth

    Science.gov (United States)

    Morgan, Yvette; Sinatra, Richard; Eschenauer, Robert

    2015-01-01

    Described is a 4-year model of a Gaining Early Awareness and Readiness for Undergraduate Program (GEAR UP) offered to 294 academically and economically disadvantaged students and their parents during in- and out-of-school time activities through partnerships forged with school personnel and community-based agencies. In an urban high school where…

  16. Rapid Increase in Reports of Syphilis Associated With Men Who Have Sex With Women and Women Who Have Sex With Men, Japan, 2012 to 2016

    Science.gov (United States)

    Takahashi, Takuri; Arima, Yuzo; Yamagishi, Takuya; Nishiki, Shingo; Kanai, Mizue; Ishikane, Masahiro; Matsui, Tamano; Sunagawa, Tomimasa; Ohnishi, Makoto; Oishi, Kazunori

    2018-01-01

    Background In Japan, syphilis reports have recently increased rapidly. However, unlike other developed countries where men who have sex with men (MSM) were associated with the rise, the increase in Japan has been attributed more to men who have sex with women (MSW) and women who have sex with men (WSM). We report on this increase based on surveillance data. Methods Syphilis is a notifiable disease requiring all laboratory-confirmed cases to be reported; stage and sex of the sex partner(s) suspected as the infection source are also reported. Focusing on primary and secondary (P&S) cases, we describe the temporal, demographic, and geographic distributions of reported cases in 2012 through 2016. Results A total of 7040 (64.0%) of 10,997 cases were P&S; the annual rate of increase was greatest for P&S and the proportion of P&S increased over time. Among P&S cases (1609 MSM, 2768 MSW, and 1323 WSM), MSW and WSM each surpassed MSM cases in 2016. Men were older with a wider age distribution (median, 37 years; interquartile range, 28–46 years) relative to women (median, 26 years; interquartile range, 21–34 years). Among women, 20- to 24-year-olds consistently had the highest reporting rate, reaching 9.0 per 100,000 in 2016. Congenital syphilis reports increased from 0.4 in 2012 to 1.4 per 100,000 live births in 2016. Although Tokyo prefecture had the highest reporting rate (3.98 per 100,000 person-years), the proportionate contribution from Tokyo decreased in 2016. Conclusions Reports on P&S syphilis increased yearly among MSW and WSM. Young women seem to be at particular risk, and with increased reports of congenital syphilis, syphilis prevention and control is currently a public health priority in Japan. PMID:29420439

  17. The linkages of anthropogenic emissions and meteorology in the rapid increase of particulate matter at a foothill city in the Arawali range of India

    Science.gov (United States)

    Yadav, Ravi; Beig, G.; Jaaffrey, S. N. A.

    2014-03-01

    The city of Udaipur (24.58°N, 73.68°E) in the province of Rajasthan in the Western part of India has a special significance as it is surrounded by the Arawali mountain ranges on one side and desert on the other side. It is located around the foothills of the rocky Arawali range. It is on the world map due to its tourist attraction. The changing pattern in particulate matter (PM2.5 and PM10) during the past three years indicates an alarming increasing trend, posing a threat to its environment & tourism sector which regulates its economy to a period during the monsoon and distribution of particulate matter is found to be governed by the meteorology and changes the trend. The level of PM10, which was already above the threshold level in 2010, further increased in 2012. The trend is found to be rapid during the months of October & November where an increase by 37% is observed in 3 years. The level of PM2.5, which is the most hazardous for respiratory system diseases, has now started to cross the ambient air quality standards set by the World Health Organization. The impact is significant during winter when the inversion layer is down due to colder temperature and foreign tourists are a peak giving rise an increased morbidity rate. The linkages of local weather with an anthropogenically induced trend and long range transport of pollutants have been outlined.

  18. Increased iron availability resulting from increased CO2 enhances carbon and nitrogen metabolism in the economical marine red macroalga Pyropia haitanensis (Rhodophyta).

    Science.gov (United States)

    Chen, Binbin; Zou, Dinghui; Yang, Yufeng

    2017-04-01

    Ocean acidification caused by rising CO 2 is predicted to increase the concentrations of dissolved species of Fe(II) and Fe(III), leading to the enhanced photosynthetic carbon sequestration in some algal species. In this study, the carbon and nitrogen metabolism in responses to increased iron availability under two CO 2 levels (390 μL L -1 and 1000 μL L -1 ), were investigated in the maricultivated macroalga Pyropia haitanensis (Rhodophyta). The results showed that, elevated CO 2 increased soluble carbonhydrate (SC) contents, resulting from enhanced photosynthesis and photosynthetic pigment synthesis in this algae, but declined its soluble protein (SP) contents, resulting in increased ratio of SC/SP. This enhanced photosynthesis performance and carbon accumulation was more significant under iron enrichment condition in seawater, with higher iron uptake rate at high CO 2 level. As a key essential biogenic element for algae, Fe-replete functionally contributed to P. haitanensis photosynthesis. Increased SC fundamentally provided carbon skeletons for nitrogen assimilation. The significant increase of carbon and nitrogen assimilation finally contributed to enhanced growth in this alga. This was also intuitively reflected by respiration that provided energy for cellular metabolism and algal growth. We propose that, in the predicted scenario of rising atmospheric CO 2 , P. haitanensis is capable to adjust its physiology by increasing its carbon and nitrogen metabolism to acclimate the acidified seawater, at the background of global climate change and simultaneously increased iron concentration due to decreased pH levels. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. NICE recommendations for the assessment of stable chest pain: assessing the early economic and service impact in the rapid-access chest pain service.

    Science.gov (United States)

    Ashrafi, Reza; Raga, Santosh; Abdool, Ali; Disney, Andrew; Wong, Peter; Davis, Gershan K

    2013-05-01

    In 2010, guidelines published by the National Institute for Clinical Excellence (NICE) suggested a change in the way patients with stable chest pain of suspected cardiac origin were investigated. These guidelines removed exercise treadmill testing from routine use and introduced cardiac CT to regular use. To investigate whether these guidelines had improved our service provision by reducing the number of further investigations required to make a diagnosis, and to see if our costs had increased now that the less expensive exercise treadmill tests were not recommended. Clinic letters were used to assess patients pretest likelihood of coronary artery disease for two six-month cohorts of consecutive patients seen in the rapid access chest pain clinic (January-June 2010 and July-December 2011) using NICE published methodology, and to ascertain which investigations patients had. Using NICE modelled costs, we generated comparative hypothetical costs for each cohort and an average cost per patient. In the January-June 2010 cohort, 435 patients with chest pain were seen, and in July-December 2011, 334 patients were seen. In the pre-NICE guidelines cohort, 23% of patients required two investigations as compared with 11.4% in the post-NICE guidelines cohort, with no patient requiring three investigations as compared with 3% in the original cohort. There was no significant increase in costs per patient in the post-NICE guidance group. Implementing NICE guidance reduced the number of investigations needed per patient, and did not prove more expensive for our department in the short term.

  20. Osmotic Edema Rapidly Increases Neuronal Excitability Through Activation of NMDA Receptor-Dependent Slow Inward Currents in Juvenile and Adult Hippocampus

    Directory of Open Access Journals (Sweden)

    Kelli Lauderdale

    2015-09-01

    Full Text Available Cellular edema (cell swelling is a principal component of numerous brain disorders including ischemia, cortical spreading depression, hyponatremia, and epilepsy. Cellular edema increases seizure-like activity in vitro and in vivo, largely through nonsynaptic mechanisms attributable to reduction of the extracellular space. However, the types of excitability changes occurring in individual neurons during the acute phase of cell volume increase remain unclear. Using whole-cell patch clamp techniques, we report that one of the first effects of osmotic edema on excitability of CA1 pyramidal cells is the generation of slow inward currents (SICs, which initiate after approximately 1 min. Frequency of SICs increased as osmolarity decreased in a dose-dependent manner. Imaging of real-time volume changes in astrocytes revealed that neuronal SICs occurred while astrocytes were still in the process of swelling. SICs evoked by cell swelling were mainly nonsynaptic in origin and NMDA receptor-dependent. To better understand the relationship between SICs and changes in neuronal excitability, recordings were performed in increasingly physiological conditions. In the absence of any added pharmacological reagents or imposed voltage clamp, osmotic edema induced excitatory postsynaptic potentials and burst firing over the same timecourse as SICs. Like SICs, action potentials were blocked by NMDAR antagonists. Effects were more pronounced in adult (8–20 weeks old compared with juvenile (P15–P21 mice. Together, our results indicate that cell swelling triggered by reduced osmolarity rapidly increases neuronal excitability through activation of NMDA receptors. Our findings have important implications for understanding nonsynaptic mechanisms of epilepsy in relation to cell swelling and reduction of the extracellular space.

  1. Fiscal greening and energy. Part 2. Economic effects of increase and broadening of the Regulating Energy Levy (REB)

    International Nuclear Information System (INIS)

    Lijesen, M.; Mulder, M.; Vromans, M.

    2001-07-01

    For the benefit of the discussion on greening the Dutch tax system, The Netherlands Bureau for Economic Policy Analysis (CPB) has made an analysis of the economic and environmental effects of raising the energy tax in the Netherlands, the so called Regulating Energy Tax.This energy tax is introduced in 1996 and has been raised in the following years in order to encourage energy efficiency improvement and the production of renewable energy. Since the introduction and the raising of this energy tax is coupled with a reduction of the tax tariffs on labour and capital, the tax basis is shifted towards environment polluting factors.This tax shift is called 'greening the tax system'. Five variants for raising the energy tax are analysed. In two of these variants the existing tariffs are raised by maintaining the existing exemption for energy use above a certain level. In the other two variants this level is raised, meaning that a larger part of the total energy use is taxed.In addition to these 4 variants, CPB has formulated a variant in which taxes have to be paid for all energy use without any exemption. In the long run uniform marginal tariffs for all energy users is the most efficient variant. Measures to reduce emissions will then be taken by the firms and households where the marginal reduction costs are relatively low. In the medium run the environmental and macroeconomic effects are almost the same in all variants. Raising the energy tax will result in a reduction of the emissions of CO2 in 2020 by 2,5 -8,5 Mton. The explanation for this range is the existence of large uncertainties concerning the development of costs and non-financial bottlenecks in the field of renewable energy production. The macro-economic costs of all variants in 2020 will be less then 0,1% GDP. The differences in environmental and macro-economic effects in the medium run are too small and the uncertainties about these effects are too large to rank these variants according their cost

  2. Age-period-cohort projections of ischaemic heart disease mortality by socio-economic position in a rapidly transitioning Chinese population

    OpenAIRE

    Wong, IOL; Schooling, CM; Cowling, BJ; Leung, GM

    2013-01-01

    Background:With economic development and population aging, ischaemic heart disease (IHD) is becoming a leading cause of mortality with widening inequalities in China. To forewarn the trends in China we projected IHD trends in the most economically developed part of China, i.e., Hong Kong.Methods:Based on sex-specific IHD mortality rates from 1976 to 2005, we projected mortality rates by neighborhood-level socio-economic position (i.e., low- or high-income groups) to 2020 in Hong Kong using Po...

  3. Reforming the IMF to Increase FDI Led Economic Growth: The Case of Latin American and Caribbean Countries

    Directory of Open Access Journals (Sweden)

    Ashraf Mahate

    2018-01-01

    Full Text Available There is a strong body of literature that finds a direct connection between inward foreign direct investment and economic growth in the host country. At the same time, economic growth in the host country attracts additional Foreign Direct Investment (FDI. This bidirectional relationship can be supported by the IMF through its lending program to countries to assist in dealing with short-term shocks as well as managing more long-term structural issues. In fact, the IMF programs in theory should provide an indicator to potential investors that the country is committed to making a change and opening its economy, which are typical requirements under IMF conditions. IMF intervention should lead to a positive impact on inward FDI. This study examines the impact of IMF-support programs on inward FDI for a sample of Latin American and Caribbean Countries. The results from this study reveal that being on an IMF borrowing program has a negative impact on inward FDI in the second and third year. We argue that being on an IMF borrowing program does not provide inward FDI with the seal of approval that it requires in making an investment.

  4. Using Increases in Criminal Deportees from the US to Estimate the Effect of Crime on Economic Growth and Development in Latin America and the Caribbean

    Directory of Open Access Journals (Sweden)

    Garfield O. Blake

    2015-11-01

    Full Text Available Previous empirical studies have uncovered little evidence that crime hinders development, possibly due to simultaneity problems. This paper uses the increase in criminal deportees from the US as an instrumental variable to identify the causal effect of crime on economic growth and development. An increase in the number of criminal deportees received by a country is shown to substantially increase that country’s homicide rate. Using panel data for a sample of 30 Latin America and the Caribbean (LAC countries, I show that the increase in crime is becoming a major obstacle to growth and development in the region.

  5. Increasing biopsy number and sampling from gastric body improve the sensitivity of rapid urease test in patients with peptic ulcer bleeding.

    Science.gov (United States)

    Lee, Tzong-Hsi; Lin, Chien-Chu; Chung, Chen-Shuan; Lin, Cheng-Kuan; Liang, Cheng-Chao; Tsai, Kuang-Chau

    2015-02-01

    Previous studies demonstrated that the sensitivity of rapid urease test (RUT) for diagnosis of Helicobacter pylori infection decreased during peptic ulcer bleeding. We designed this study and tried to find a better method to improve the detection rate of H. pylori infection at the same session of endoscopic diagnosis of peptic ulcer bleeding. We prospectively enrolled 116 patients with peptic ulcer bleeding. These patients received intravenous proton pump inhibitor and then received upper gastrointestinal endoscopy within 24 h after arrival. We took one piece of biopsy from gastric antrum (Group 1), four pieces from gastric antrum (Group 2), and one piece from the gastric body (Group 3) for three separate RUTs, respectively. (13)C-urease breath test was used as gold standard for diagnosis of H. pylori infection. There were 74 patients (64 %) with positive (13)C-urease breath test. Among these 74 patients, 45 patients had positive RUT (sensitivity: 61 %) in Group 1; 55 patients had positive RUT (sensitivity: 74 %) in Group 2; 54 patients had positive RUT (sensitivity: 73 %) in Group 3. There were significant differences between Group 1 and Group 2 (p = 0.02) and between Group 1 and Group 3 (p = 0.022). The sensitivity of RUT was 61 % during peptic ulcer bleeding. The sensitivity of RUT can be increased significantly by increased biopsy number from gastric antrum or biopsy from gastric body.

  6. Economic liberalization and globalization vs. India's poor

    OpenAIRE

    Oschinski, Matthias

    2003-01-01

    Today, many in the national and international NGO community perceive globalization and economic liberalization as a threat claiming that it widens inequalities and increases overall poverty. While it is true that inequality is on the rise in a rapidly globalizing world the real culprit is not globalization itself but rather a lack of economic reforms and economic liberalization. This paper aims to show that many in the international NGO community confuse cause and effect. The root cause of po...

  7. Increased crop failure due to climate change: assessing adaptation options using models and socio-economic data for wheat in China

    Energy Technology Data Exchange (ETDEWEB)

    Challinor, Andrew J [Institute for Climate and Atmospheric Science, School of Earth and Environment, University of Leeds, Leeds LS2 9JT (United Kingdom); Simelton, Elisabeth S; Fraser, Evan D G [Sustainability Research Institute, School of Earth and Environment, University of Leeds, Leeds LS2 9JT (United Kingdom); Hemming, Debbie; Collins, Mathew, E-mail: a.j.challinor@leeds.ac.uk [Met Office Hadley Centre, FitzRoy Road, Exeter EX1 3PB (United Kingdom)

    2010-07-15

    Tools for projecting crop productivity under a range of conditions, and assessing adaptation options, are an important part of the endeavour to prioritize investment in adaptation. We present ensemble projections of crop productivity that account for biophysical processes, inherent uncertainty and adaptation, using spring wheat in Northeast China as a case study. A parallel 'vulnerability index' approach uses quantitative socio-economic data to account for autonomous farmer adaptation. The simulations show crop failure rates increasing under climate change, due to increasing extremes of both heat and water stress. Crop failure rates increase with mean temperature, with increases in maximum failure rates being greater than those in median failure rates. The results suggest that significant adaptation is possible through either socio-economic measures such as greater investment, or biophysical measures such as drought or heat tolerance in crops. The results also show that adaptation becomes increasingly necessitated as mean temperature and the associated number of extremes rise. The results, and the limitations of this study, also suggest directions for research for linking climate and crop models, socio-economic analyses and crop variety trial data in order to prioritize options such as capacity building, plant breeding and biotechnology.

  8. Increasing efficiency in ethanol production: Water footprint and economic productivity of sugarcane ethanol under nine different water regimes in north-eastern Brazil

    Directory of Open Access Journals (Sweden)

    Daniel Chico

    2015-06-01

    Full Text Available Ethanol production in Brazil has grown by 219% between 2001 and 2012, increasing the use of land and water resources. In the semi-arid north-eastern Brazil, irrigation is the main way for improving sugarcane production. This study aimed at quantifying water consumed in ethanol production from sugarcane in this region using the water footprint (WF indicator and complementing it with an evaluation of the water apparent productivity (WAP. This way we were able to provide a measure of the crop´s physical and economic water productivity using, respectively, the WF and WAP concepts. We studied sugarcane cultivation under nine different water regimes, including rainfed and full irrigation. Data from a mill of the state of Alagoas for three production seasons were used. Irrigation influenced sugarcane yield increasing total profit per hectare and economic water productivity. Full irrigation showed the lowest WF, 1229 litres of water per litre of ethanol (L/L, whereas rainfed production showed the highest WF, 1646 L/L. However, the lower WF in full irrigation as compared to the rest of the water regimes implied the use of higher volumes of blue water per cultivated hectare. Lower water regimes yielded the lowest economic productivity, 0.72 US$/m3 for rainfed production as compared to 1.11 US$/m3 for full irrigation. Since economic revenues are increased with higher water regimes, there are incentives for the development of these higher water regimes. This will lead to higher general crop water and economic productivity at field level, as green water is replaced by blue water consumption.

  9. Increasing efficiency in ethanol production: Water footprint and economic productivity of sugarcane ethanol under nine different water regimes in north-eastern Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Chico, D.; Santiago, A. D.; Garrido, A.

    2015-07-01

    Ethanol production in Brazil has grown by 219% between 2001 and 2012, increasing the use of land and water resources. In the semi-arid north-eastern Brazil, irrigation is the main way for improving sugarcane production. This study aimed at quantifying water consumed in ethanol production from sugarcane in this region using the water footprint (WF) indicator and complementing it with an evaluation of the water apparent productivity (WAP). This way we were able to provide a measure of the crop´s physical and economic water productivity using, respectively, the WF and WAP concepts. We studied sugarcane cultivation under nine different water regimes, including rainfed and full irrigation. Data from a mill of the state of Alagoas for three production seasons were used. Irrigation influenced sugarcane yield increasing total profit per hectare and economic water productivity. Full irrigation showed the lowest WF, 1229 litres of water per litre of ethanol (L/L), whereas rainfed production showed the highest WF, 1646 L/L. However, the lower WF in full irrigation as compared to the rest of the water regimes implied the use of higher volumes of blue water per cultivated hectare. Lower water regimes yielded the lowest economic productivity, 0.72 US$/m3 for rainfed production as compared to 1.11 US$/m3 for full irrigation. Since economic revenues are increased with higher water regimes, there are incentives for the development of these higher water regimes. This will lead to higher general crop water and economic productivity at field level, as green water is replaced by blue water consumption. (Author)

  10. Eating 'Junk-Food' Produces Rapid and Long-Lasting Increases in NAc CP-AMPA Receptors: Implications for Enhanced Cue-Induced Motivation and Food Addiction.

    Science.gov (United States)

    Oginsky, Max F; Goforth, Paulette B; Nobile, Cameron W; Lopez-Santiago, Luis F; Ferrario, Carrie R

    2016-12-01

    Urges to eat are influenced by stimuli in the environment that are associated with food (food cues). Obese people are more sensitive to food cues, reporting stronger craving and consuming larger portions after food cue exposure. The nucleus accumbens (NAc) mediates cue-triggered motivational responses, and activations in the NAc triggered by food cues are stronger in people who are susceptible to obesity. This has led to the idea that alterations in NAc function similar to those underlying drug addiction may contribute to obesity, particularly in obesity-susceptible individuals. Motivational responses are mediated in part by NAc AMPA receptor (AMPAR) transmission, and recent work shows that cue-triggered motivation is enhanced in obesity-susceptible rats after 'junk-food' diet consumption. Therefore, here we determined whether NAc AMPAR expression and function is increased by 'junk-food' diet consumption in obesity-susceptible vs -resistant populations using both outbred and selectively bred models of susceptibility. In addition, cocaine-induced locomotor activity was used as a general 'read out' of mesolimbic function after 'junk-food' consumption. We found a sensitized locomotor response to cocaine in rats that gained weight on a 'junk-food' diet, consistent with greater responsivity of mesolimbic circuits in obesity-susceptible groups. In addition, eating 'junk-food' increased NAc calcium-permeable-AMPAR (CP-AMPAR) function only in obesity-susceptible rats. This increase occurred rapidly, persisted for weeks after 'junk-food' consumption ceased, and preceded the development of obesity. These data are considered in light of enhanced cue-triggered motivation and striatal function in obesity-susceptible rats and the role of NAc CP-AMPARs in enhanced motivation and addiction.

  11. Eating ‘Junk-Food' Produces Rapid and Long-Lasting Increases in NAc CP-AMPA Receptors: Implications for Enhanced Cue-Induced Motivation and Food Addiction

    Science.gov (United States)

    Oginsky, Max F; Goforth, Paulette B; Nobile, Cameron W; Lopez-Santiago, Luis F; Ferrario, Carrie R

    2016-01-01

    Urges to eat are influenced by stimuli in the environment that are associated with food (food cues). Obese people are more sensitive to food cues, reporting stronger craving and consuming larger portions after food cue exposure. The nucleus accumbens (NAc) mediates cue-triggered motivational responses, and activations in the NAc triggered by food cues are stronger in people who are susceptible to obesity. This has led to the idea that alterations in NAc function similar to those underlying drug addiction may contribute to obesity, particularly in obesity-susceptible individuals. Motivational responses are mediated in part by NAc AMPA receptor (AMPAR) transmission, and recent work shows that cue-triggered motivation is enhanced in obesity-susceptible rats after ‘junk-food' diet consumption. Therefore, here we determined whether NAc AMPAR expression and function is increased by ‘junk-food' diet consumption in obesity-susceptible vs -resistant populations using both outbred and selectively bred models of susceptibility. In addition, cocaine-induced locomotor activity was used as a general ‘read out' of mesolimbic function after ‘junk-food' consumption. We found a sensitized locomotor response to cocaine in rats that gained weight on a ‘junk-food' diet, consistent with greater responsivity of mesolimbic circuits in obesity-susceptible groups. In addition, eating ‘junk-food' increased NAc calcium-permeable-AMPAR (CP-AMPAR) function only in obesity-susceptible rats. This increase occurred rapidly, persisted for weeks after ‘junk-food' consumption ceased, and preceded the development of obesity. These data are considered in light of enhanced cue-triggered motivation and striatal function in obesity-susceptible rats and the role of NAc CP-AMPARs in enhanced motivation and addiction. PMID:27383008

  12. Analysis of Human Resource Competency as Effort to Increase SMEs Economic Sector Productivity with Gender as Differentiating Variable

    OpenAIRE

    Wibawa, Dian Prihardini

    2018-01-01

    Competence is a very important factor in increasing work productivity. A qualified workforce will have a positive impact on improving business productivity. Thus, the level of corporate profitability also increased. Human resource improvement strategy is an excellent strategy apart from other factors such as technology improves. Increased strategy through human resource competence can be done with the improvement of ability, attitude, knowledge, and expertise. The purpose of this research is ...

  13. Plasma leptin and growth hormone levels in the fine flounder (Paralichthys adspersus) increase gradually during fasting and decline rapidly after refeeding.

    Science.gov (United States)

    Fuentes, Eduardo N; Kling, Peter; Einarsdottir, Ingibjörg Eir; Alvarez, Marco; Valdés, Juan Antonio; Molina, Alfredo; Björnsson, Björn Thrandur

    2012-05-15

    In fish, recent studies have indicated an anorexigenic role of leptin and thus its possible involvement in regulation of energy balance and growth. In the present study, the effects of fasting and refeeding periods on plasma leptin levels were studied in the fine flounder, a flatfish with remarkably slow growth. To further assess the endocrine status of the fish during periods of catabolism and anabolism, plasma growth hormone (GH) levels were also analyzed. Under normal feeding condition, plasma leptin and GH levels remained stable and relatively high in comparison with other teleost species. For the three separate groups of fish, fasted for 2, 3, and 4 weeks, respectively, plasma leptin levels increase gradually, becoming significantly elevated after 3 weeks, and reaching highest levels after 4-week fasting. Plasma GH levels were significantly elevated after 2-week fasting. At the onset of refeeding, following a single meal, leptin levels decline rapidly to lower than initial levels within 2 h, irrespective of the length of fasting. Plasma GH also decline, the decrease being significant after 4, 24 and 2 h for the 2, 3 and 4-week fasted groups, respectively. This study shows that plasma leptin levels in the fine flounder are strongly linked to nutritional status and suggests that leptin secretion is regulated by fast-acting mechanisms. Elevated leptin levels in fasted fish may contribute to a passive survival strategy of species which experience natural food shortage periods by lowering appetite and limiting physical foraging activity. Copyright © 2012 Elsevier Inc. All rights reserved.

  14. Essential roles of GABA transporter-1 in controlling rapid eye movement sleep and in increased slow wave activity after sleep deprivation.

    Directory of Open Access Journals (Sweden)

    Xin-Hong Xu

    Full Text Available GABA is the major inhibitory neurotransmitter in the mammalian central nervous system that has been strongly implicated in the regulation of sleep. GABA transporter subtype 1 (GAT1 constructs high affinity reuptake sites for GABA and regulates GABAergic transmission in the brain. However, the role of GAT1 in sleep-wake regulation remains elusive. In the current study, we characterized the spontaneous sleep-wake cycle and responses to sleep deprivation in GAT1 knock-out (KO mice. GAT1 KO mice exhibited dominant theta-activity and a remarkable reduction of EEG power in low frequencies across all vigilance stages. Under baseline conditions, spontaneous rapid eye movement (REM sleep of KO mice was elevated both during the light and dark periods, and non-REM (NREM sleep was reduced during the light period only. KO mice also showed more state transitions from NREM to REM sleep and from REM sleep to wakefulness, as well as more number of REM and NREM sleep bouts than WT mice. During the dark period, KO mice exhibited more REM sleep bouts only. Six hours of sleep deprivation induced rebound increases in NREM and REM sleep in both genotypes. However, slow wave activity, the intensity component of NREM sleep was briefly elevated in WT mice but remained completely unchanged in KO mice, compared with their respective baselines. These results indicate that GAT1 plays a critical role in the regulation of REM sleep and homeostasis of NREM sleep.

  15. Increase in socio-economic value of the fresh water fishery by reductions in the sulfur precipitation. [Norway]. Oekt samfunnsoekonomisk verdi av ferskvannsfisket ved reduksjoner i svovelnedfallet

    Energy Technology Data Exchange (ETDEWEB)

    Navrud, S

    1985-01-29

    A reduction of about 30% in the sulfur out-lets in Europe would lead to approximately the same reduction in acid precipitation in the South of Norway. The resulting improvement of water quality would facilitate improvements in the fish population. The report discussed various methods of measuring the socio-economic value of an assumed marginal increase of the amount of fresh water fish and recommends a ''parcel of methods'' in order to solve the estimation problem. A reduction of 30% in the acid precipitation would result in a total yearly socio-economic value increase of approximately 37 millions Norwegian kroners measured by the total willingness of payment by the Norwegian population - wich probably is an underestimation. 66 references, 22 drawings, 5 tables.

  16. Households across all income quintiles, especially the poorest, increased animal source food expenditures substantially during recent Peruvian economic growth.

    Science.gov (United States)

    Humphries, Debbie L; Behrman, Jere R; Crookston, Benjamin T; Dearden, Kirk A; Schott, Whitney; Penny, Mary E

    2014-01-01

    Relative to plant-based foods, animal source foods (ASFs) are richer in accessible protein, iron, zinc, calcium, vitamin B-12 and other nutrients. Because of their nutritional value, particularly for childhood growth and nutrition, it is important to identify factors influencing ASF consumption, especially for poorer households that generally consume less ASFs. To estimate differential responsiveness of ASF consumption to changes in total household expenditures for households with different expenditures in a middle-income country with substantial recent income increases. The Peruvian Young Lives household panel (n = 1750) from 2002, 2006 and 2009 was used to characterize patterns of ASF expenditures. Multivariate models with controls for unobserved household fixed effects and common secular trends were used to examine nonlinear relationships between changes in household expenditures and in ASF expenditures. Households with lower total expenditures dedicated greater percentages of expenditures to food (58.4% vs.17.9% in 2002 and 24.2% vs. 21.5% in 2009 for lowest and highest quintiles respectively) and lower percentages of food expenditures to ASF (22.8% vs. 33.9% in 2002 and 30.3% vs. 37.6% in 2009 for lowest and highest quintiles respectively). Average percentages of overall expenditures spent on food dropped from 47% to 23.2% between 2002 and 2009. Households in the lowest quintiles of expenditures showed greater increases in ASF expenditures relative to total consumption than households in the highest quintiles. Among ASF components, meat and poultry expenditures increased more than proportionately for households in the lowest quintiles, and eggs and fish expenditures increased less than proportionately for all households. Increases in household expenditures were associated with substantial increases in consumption of ASFs for households, particularly households with lower total expenditures. Increases in ASF expenditures for all but the top quintile of

  17. Effect of increasing the price of sugar-sweetened beverages on alcoholic beverage purchases: an economic analysis of sales data.

    Science.gov (United States)

    Quirmbach, Diana; Cornelsen, Laura; Jebb, Susan A; Marteau, Theresa; Smith, Richard

    2018-04-01

    Taxing soft-drinks may reduce their purchase, but assessing the impact on health demands wider consideration on alternative beverage choices. Effects on alcoholic drinks are of particular concern, as many contain similar or greater amounts of sugar than soft-drinks and have additional health harms. Changes in consumption of alcoholic drinks may reinforce or negate the intended effect of price changes for soft-drinks. A partial demand model, adapted from the Almost Ideal Demand System, was applied to Kantar Worldpanel data from 31 919 households from January 2012 to December 2013, covering drink purchases for home consumption, providing ~6 million purchases aggregated into 11 groups, including three levels of soft-drink, three of other non-alcoholic drinks and five of alcoholic drinks. An increase in the price of high-sugar drinks leads to an increase in the purchase of lager, an increase in the price of medium-sugar drinks reduces purchases of alcoholic drinks, while an increase in the price of diet/low-sugar drinks increases purchases of beer, cider and wines. Overall, the effects of price rises are greatest in the low-income group. Increasing the price of soft-drinks may change purchase patterns for alcohol. Increasing the price of medium-sugar drinks has the potential to have a multiplier-effect beneficial to health through reducing alcohol purchases, with the converse for increases in the price of diet-drinks. Although the reasons for such associations cannot be explained from this analysis, requiring further study, the design of fiscal interventions should now consider these wider potential outcomes. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  18. Behavioral Economics, Wearable Devices, and Cooperative Games: Results From a Population-Based Intervention to Increase Physical Activity.

    Science.gov (United States)

    van Mierlo, Trevor; Hyatt, Douglas; Ching, Andrew T; Fournier, Rachel; Dembo, Ron S

    2016-01-28

    Health care literature supports the development of accessible interventions that integrate behavioral economics, wearable devices, principles of evidence-based behavior change, and community support. However, there are limited real-world examples of large scale, population-based, member-driven reward platforms. Subsequently, a paucity of outcome data exists and health economic effects remain largely theoretical. To complicate matters, an emerging area of research is defining the role of Superusers, the small percentage of unusually engaged digital health participants who may influence other members. The objective of this preliminary study is to analyze descriptive data from GOODcoins, a self-guided, free-to-consumer engagement and rewards platform incentivizing walking, running and cycling. Registered members accessed the GOODcoins platform through PCs, tablets or mobile devices, and had the opportunity to sync wearables to track activity. Following registration, members were encouraged to join gamified group challenges and compare their progress with that of others. As members met challenge targets, they were rewarded with GOODcoins, which could be redeemed for planet- or people-friendly products. Outcome data were obtained from the GOODcoins custom SQL database. The reporting period was December 1, 2014 to May 1, 2015. Descriptive self-report data were analyzed using MySQL and MS Excel. The study period includes data from 1298 users who were connected to an exercise tracking device. Females consisted of 52.6% (n=683) of the study population, 33.7% (n=438) were between the ages of 20-29, and 24.8% (n=322) were between the ages of 30-39. 77.5% (n=1006) of connected and active members met daily-recommended physical activity guidelines of 30 minutes, with a total daily average activity of 107 minutes (95% CI 90, 124). Of all connected and active users, 96.1% (n=1248) listed walking as their primary activity. For members who exchanged GOODcoins, the mean balance was 4

  19. Socio-economic significance of mangroves in India

    Digital Repository Service at National Institute of Oceanography (India)

    Untawale, A.G.; Wafar, S.

    Mangrove ecosystem is considered ecologically and economically important perhaps due to its high productivity. However, due to the lack of proper scientific knowledge as well as the rapid increase in various developmental pressures along the coastal...

  20. Increased incidence of tuberculosis in zimbabwe, in association with food insecurity, and economic collapse: an ecological analysis.

    Science.gov (United States)

    Burke, Stephen J; Lass, Elliot; Thistle, Paul; Katumbe, Lovemore; Jetha, Arif; Schwarz, Dan; Bolotin, Shelly; Barker, R D; Simor, Andrew; Silverman, Michael

    2014-01-01

    Zimbabwe underwent a socioeconomic crisis and resultant increase in food insecurity in 2008-9. The impact of the crisis on Tuberculosis (TB) incidence is unknown. Prospective databases from two mission hospitals, which were geographically widely separated, and remained open during the crisis, were reviewed. At the Howard Hospital (HH) in northern Zimbabwe, TB incidence increased 35% in 2008 from baseline rates in 2003-2007 (pcrisis at HH showed a decrease of 33% in TB incidence between 2009 to 2010 (pcrisis years of 2008/2009 (pcrisis in this high HIV prevalence country.

  1. Dexamethasone rapidly increases GABA release in the dorsal motor nucleus of the vagus via retrograde messenger-mediated enhancement of TRPV1 activity.

    Directory of Open Access Journals (Sweden)

    Andrei V Derbenev

    Full Text Available Glucocorticoids influence vagal parasympathetic output to the viscera via mechanisms that include modulation of neural circuitry in the dorsal vagal complex, a principal autonomic regulatory center. Glucocorticoids can modulate synaptic neurotransmitter release elsewhere in the brain by inducing release of retrograde signalling molecules. We tested the hypothesis that the glucocorticoid agonist dexamethasone (DEX modulates GABA release in the rat dorsal motor nucleus of the vagus (DMV. Whole-cell patch-clamp recordings revealed that DEX (1-10 µM rapidly (i.e. within three minutes increased the frequency of tetrodotoxin-resistant, miniature IPSCs (mIPSCs in 67% of DMV neurons recorded in acutely prepared slices. Glutamate-mediated mEPSCs were also enhanced by DEX (10 µM, and blockade of ionotropic glutamate receptors reduced the DEX effect on mIPSC frequency. Antagonists of type I or II corticosteroid receptors blocked the effect of DEX on mIPSCs. The effect was mimicked by application of the membrane-impermeant BSA-conjugated DEX, and intracellular blockade of G protein function with GDP βS in the recorded cell prevented the effect of DEX. The enhancement of GABA release was blocked by the TRPV1 antagonists, 5'-iodoresiniferatoxin or capsazepine, but was not altered by the cannabinoid type 1 receptor antagonist AM251. The DEX effect was prevented by blocking fatty acid amide hydrolysis or by inhibiting anandamide transport, implicating involvement of the endocannabinoid system in the response. These findings indicate that DEX induces an enhancement of GABA release in the DMV, which is mediated by activation of TRPV1 receptors on afferent terminals. The effect is likely induced by anandamide or other 'endovanilloid', suggesting activation of a local retrograde signal originating from DMV neurons to enhance synaptic inhibition locally in response to glucocorticoids.

  2. The apoptotic response in HCT116BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein

    International Nuclear Information System (INIS)

    Semaan, Sheila J; Nickells, Robert W

    2010-01-01

    Many chemotherapeutic agents promote tumor cell death by activating the intrinsic pathway of apoptosis. Intrinsic apoptosis involves permeabilization of the mitochondrial outer membrane and the release of cytochrome c, a process that is controlled by proteins of the BCL2 gene family. Chemoresistance is often associated with abnormalities in concentrations of BCL2 family proteins. Although stoichiometirc interactions between anti-apoptotic and BH3-only BCL2 family proteins have been well documented as affecting cell death, the association between changes in BAX concentration and intrinsic apoptosis are poorly understood. Exogenous GFP-murine Bax fusion constructs were transfected into BAX-deficient HCT116 cells. To titrate the expression of the fusion protein, GFP-BAX was cloned into a tetracycline sensitive expression cassette and cotransfected with a plasmid expressing the rtTA transcription factor into HCT116 BAX-/- cells. Linear expression of the fusion gene was induced with doxycycline and monitored by quantitative PCR and immunoblotting. Cell death was assayed by DAPI staining cells after exposure to indomethacin, and scoring nuclei for condensed chromatin and fragmented nuclei. HCT116 BAX-/- cells were resistant to indomethacin, but susceptibility could be recovered in cells expressing a GFP-BAX fusion protein. Titration of GFP-BAX expression revealed that the concentration of BAX required to induce a saturating apoptosis response from baseline, was rapidly achieved. Increased levels of GFP-BAX were unable to stimulate higher levels of cell death. Examination of GFP-BAX distribution before and after indomethacin treatment indicated that BAX protein did not form aggregates when present at sub-lethal concentrations. Within the limitations of this experimental system, BAX-dependent apoptosis in HCT116 cells exhibits an all-or-none response depending on the level of BAX protein present. The lack of BAX aggregation at sub-saturation levels suggests that the

  3. The apoptotic response in HCT116BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein

    Directory of Open Access Journals (Sweden)

    Semaan Sheila J

    2010-10-01

    Full Text Available Abstract Background Many chemotherapeutic agents promote tumor cell death by activating the intrinsic pathway of apoptosis. Intrinsic apoptosis involves permeabilization of the mitochondrial outer membrane and the release of cytochrome c, a process that is controlled by proteins of the BCL2 gene family. Chemoresistance is often associated with abnormalities in concentrations of BCL2 family proteins. Although stoichiometirc interactions between anti-apoptotic and BH3-only BCL2 family proteins have been well documented as affecting cell death, the association between changes in BAX concentration and intrinsic apoptosis are poorly understood. Methods Exogenous GFP-murine Bax fusion constructs were transfected into BAX-deficient HCT116 cells. To titrate the expression of the fusion protein, GFP-BAX was cloned into a tetracycline sensitive expression cassette and cotransfected with a plasmid expressing the rtTA transcription factor into HCT116BAX-/- cells. Linear expression of the fusion gene was induced with doxycycline and monitored by quantitative PCR and immunoblotting. Cell death was assayed by DAPI staining cells after exposure to indomethacin, and scoring nuclei for condensed chromatin and fragmented nuclei. Results HCT116BAX-/- cells were resistant to indomethacin, but susceptibility could be recovered in cells expressing a GFP-BAX fusion protein. Titration of GFP-BAX expression revealed that the concentration of BAX required to induce a saturating apoptosis response from baseline, was rapidly achieved. Increased levels of GFP-BAX were unable to stimulate higher levels of cell death. Examination of GFP-BAX distribution before and after indomethacin treatment indicated that BAX protein did not form aggregates when present at sub-lethal concentrations. Conclusion Within the limitations of this experimental system, BAX-dependent apoptosis in HCT116 cells exhibits an all-or-none response depending on the level of BAX protein present. The lack of

  4. Assessing the economic impact of public investment in Malaysia: a case study on MyRapid Transit project using a dynamic computable general equilibrium model

    OpenAIRE

    Muniandy, Meenachi

    2017-01-01

    The central focus of this thesis is the question of whether public investment in transport infrastructure contributes positively to Malaysia’s economic growth and welfare. Although there are strong analytical reasons to believe that public investment spending is one of the important variables that influence growth, there remains significant uncertainty about its actual degree of influence. In Malaysia, whenever there is a collapse in domestic demand, government spending becomes an important m...

  5. Rapid Electrical Stimulation Increased Cardiac Apoptosis Through Disturbance of Calcium Homeostasis and Mitochondrial Dysfunction in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

    Directory of Open Access Journals (Sweden)

    Le Geng

    2018-06-01

    Full Text Available Background/Aims: Heart failure induced by tachycardia, the most common arrhythmia, is frequently observed in clinical practice. This study was designed to investigate the underlying mechanisms. Methods: Rapid electrical stimulation (RES at a frequency of 3 Hz was applied on human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs for 7 days, with 8 h/day and 24 h/day set to represent short-term and long-term tachycardia, respectively. Age-matched hiPSC-CMs without electrical stimulation or with slow electrical stimulation (1 Hz were set as no electrical stimulation (NES control or low-frequency electrical stimulation (LES control. Following stimulation, JC-1 staining flow cytometry analysis was performed to examine mitochondrial conditions. Apoptosis in hiPSC-CMs was evaluated using Hoechst staining and Annexin V/propidium iodide (AV/PI staining flow cytometry analysis. Calcium transients and L-type calcium currents were recorded to evaluate calcium homeostasis. Western blotting and qPCR were performed to evaluate the protein and mRNA expression levels of apoptosis-related genes and calcium homeostasis-regulated genes. Results: Compared to the controls, hiPSC-CMs following RES presented mitochondrial dysfunction and an increased apoptotic percentage. Amplitudes of calcium transients and L-type calcium currents were significantly decreased in hiPSC-CMs with RES. Molecular analysis demonstrated upregulated expression of Caspase3 and increased Bax/Bcl-2 ratio. Genes related to calcium re-sequence were downregulated, while phosphorylated Ca2+/calmodulin-dependent protein kinase II (CaMKII was significantly upregulated following RES. There was no significant difference between the NES control and LES control groups in these aspects. Inhibition of CaMKII with 1 µM KN93 partly reversed these adverse effects of RES. Conclusion: RES on hiPSC-CMs disturbed calcium homeostasis, which led to mitochondrial stress, promoted cell apoptosis and

  6. Cost-effectiveness of Bariatric Surgery: Increasing the Economic Viability of the Most Effective Treatment for Type II Diabetes Mellitus.

    Science.gov (United States)

    Warren, Jeremy A; Ewing, Joseph A; Hale, Allyson L; Blackhurst, Dawn W; Bour, Eric S; Scott, John D

    2015-08-01

    There has been considerable debate on the cost-effectiveness of bariatric surgery within larger population groups. Despite the recognition that morbid obesity and its comorbidities are best treated surgically, insurance coverage is not universally available. One of the more costly comorbidities of obesity is Type II diabetes mellitus (T2DM). We propose a model that demonstrates the cost-effectiveness of increasing the number of bariatric surgical operations performed on patients with T2DM in the United States. We applied published population cost estimates (2012) for medical care of T2DM to a retrospective cohort of morbidly obese patients in South Carolina. We compared differences in 10-year medical costs between those having bariatric surgery and controls. Resolution of T2DM in the bariatric cohort was assumed to be 40 per cent. Considering only the direct medical costs of T2DM, the 10-year aggregate cost savings compared with a control group is $2.7 million/1000 patients; the total (direct and indirect) cost savings is $5.4 million/1000 patients. When considering resolution of T2DM alone, increasing the number of bariatric operations for a given population leads to a substantial cost savings over a 10-year period. This study adds to the growing body of evidence suggesting that bariatric surgery is a cost-effective means of caring for the obese patient.

  7. Medical and economic impact of extraintestinal infections due to Escherichia coli: focus on an increasingly important endemic problem.

    Science.gov (United States)

    Russo, Thomas A; Johnson, James R

    2003-04-01

    Escherichia coli is probably the best-known bacterial species and one of the most frequently isolated organisms from clinical specimens. Despite this, underappreciation and misunderstandings exist among medical professionals and the lay public alike regarding E. coli as an extraintestinal pathogen. Underappreciated features include (i) the wide variety of extraintestinal infections E. coli can cause, (ii) the high incidence and associated morbidity, mortality, and costs of these diverse clinical syndromes, (iii) the pathogenic potential of different groups of E. coli strains for causing intestinal versus extraintestinal disease, and (iv) increasing antimicrobial resistance. In this era in which health news often sensationalizes uncommon infection syndromes or pathogens, the strains of E. coli that cause extraintestinal infection are an increasingly important endemic problem and underappreciated "killers". Billions of health care dollars, millions of work days, and hundreds of thousands of lives are lost each year to extraintestinal infections due to E. coli. New treatments and prevention measures will be needed for improved outcomes and a diminished disease burden.

  8. TOURISM IN TIME OF CRISIS AND INFLUENCE IN THE PROCESS OF INCREASE ECONOMIC. COMPARATIVE ANALYSIS ROMANIA-BULGARIA-GREECE

    Directory of Open Access Journals (Sweden)

    Laura-Maria POPESCU

    2013-10-01

    Full Text Available The article shows an analysis of tourist activity in the period of crisis, as well as as far as this sector is retrieves in the process of increase in ecomonic among countries concerned. Have been taken into account three areas with different approaches in the field of tourism so as to be able to easily highlight difference between tradition in the case of Greece, exploitation and operation of the investment in Bulgaria and development in progress, in the case of Romania. In this way, the work of front proposes to analyze determinants underlying competitiveness in tourism from the perspective of the three states in direct competition, to highlight effects of communication on the competitiveness in the tourism industry. The purpose of this analysis is to provide a series of responses, from the perspective of the development strategies and communication, which could explain the results so different in its turn to the three national economy in the tourism sector.

  9. Relative Economic Merits of Storage and Combustion Turbines for Meeting Peak Capacity Requirements under Increased Penetration of Solar Photovoltaics

    Energy Technology Data Exchange (ETDEWEB)

    Denholm, Paul [National Renewable Energy Lab. (NREL), Golden, CO (United States); Diakov, Victor [National Renewable Energy Lab. (NREL), Golden, CO (United States); Margolis, Robert [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-09-01

    Batteries with several hours of capacity provide an alternative to combustion turbines for meeting peak capacity requirements. Even when compared to state-of-the-art highly flexible combustion turbines, batteries can provide a greater operational value, which is reflected in a lower system-wide production cost. By shifting load and providing operating reserves, batteries can reduce the cost of operating the power system to a traditional electric utility. This added value means that, depending on battery life, batteries can have a higher cost than a combustion turbine of equal capacity and still produce a system with equal or lower overall life-cycle cost. For a utility considering investing in new capacity, the cost premium for batteries is highly sensitive to a variety of factors, including lifetime, natural gas costs, PV penetration, and grid generation mix. In addition, as PV penetration increases, the net electricity demand profile changes, which may reduce the amount of battery energy capacity needed to reliably meet peak demand.

  10. Does demolition or refurbishment of old and inefficient homes help to increase our environmental, social and economic viability?

    International Nuclear Information System (INIS)

    Power, Anne

    2008-01-01

    The issue of whether to demolish or refurbish older housing has been debated for over a century. It has been an active policy area since the late 1880s, when the Government first authorised the statutory demolition of insanitary slums. In the 1960s, revulsion at the scale of 'demolition blight' and new building caused a rethink, leading to a major reinvestment in inner city neighbourhoods of older housing. In the past 5 years, debate on demolition and new building has been intensified by the Government's Sustainable Communities Plan of 2003, with its proposals for large-scale clearance and building. Environmental arguments about renovating the existing stock have gained increasing prominence as people have sought to defend their communities from demolition. The evidence on whether demolition would reduce the amount of greenhouse gases we emit into the atmosphere is unclear and disputed. This paper summarises the evidence and arguments, and attempts to clarify the most realistic, achievable route to major reductions in energy use in homes

  11. Does demolition or refurbishment of old and inefficient homes help to increase our environmental, social and economic viability?

    Energy Technology Data Exchange (ETDEWEB)

    Power, Anne [London School of Economics, Houghton Street, London WC2A 2AE (United Kingdom); Sustainable Development Commission, Room 101, 55 Whitehall, c/o 3-8 Whitehall Place, London SW1A 2HH (United Kingdom)

    2008-12-15

    The issue of whether to demolish or refurbish older housing has been debated for over a century. It has been an active policy area since the late 1880s, when the Government first authorised the statutory demolition of insanitary slums. In the 1960s, revulsion at the scale of 'demolition blight' and new building caused a rethink, leading to a major reinvestment in inner city neighbourhoods of older housing. In the past 5 years, debate on demolition and new building has been intensified by the Government's Sustainable Communities Plan of 2003, with its proposals for large-scale clearance and building. Environmental arguments about renovating the existing stock have gained increasing prominence as people have sought to defend their communities from demolition. The evidence on whether demolition would reduce the amount of greenhouse gases we emit into the atmosphere is unclear and disputed. This paper summarises the evidence and arguments, and attempts to clarify the most realistic, achievable route to major reductions in energy use in homes. The arguments that apply to housing also apply to most other buildings and therefore to the overall built environment, which accounts for half of all carbon emissions. Three main sources of evidence have helped in the development of this paper, but there are many other studies we draw on in the discussion.

  12. Age-period-cohort projections of ischaemic heart disease mortality by socio-economic position in a rapidly transitioning Chinese population.

    Directory of Open Access Journals (Sweden)

    Irene O L Wong

    Full Text Available BACKGROUND: With economic development and population aging, ischaemic heart disease (IHD is becoming a leading cause of mortality with widening inequalities in China. To forewarn the trends in China we projected IHD trends in the most economically developed part of China, i.e., Hong Kong. METHODS: Based on sex-specific IHD mortality rates from 1976 to 2005, we projected mortality rates by neighborhood-level socio-economic position (i.e., low- or high-income groups to 2020 in Hong Kong using Poisson age-period-cohort models with autoregressive priors. RESULTS: In the low-income group, age-standardized IHD mortality rates among women declined from 33.3 deaths in 1976-1980 to 19.7 per 100,000 in 2016-2020 (from 55.5 deaths to 34.2 per 100,000 among men. The rates in the high-income group were initially higher in both sexes, particularly among men, but this had reversed by the end of the study periods. The rates declined faster for the high-income group than for the low-income group in both sexes. The rates were projected to decline faster in the high-income group, such that by the end of the projection period the high-income group would have lower IHD mortality rates, particularly for women. Birth cohort effects varied with sex, with a marked upturn in IHD mortality around 1945, i.e., for the first generation of men to grow up in a more economically developed environment. There was no such upturn in women. Birth cohort effects were the main drivers of change in IHD mortality rates. CONCLUSION: IHD mortality rates are declining in Hong Kong and are projected to continue to do so, even taking into account greater vulnerability for the first generation of men born into a more developed environment. At the same time social disparities in IHD have reversed and are widening, partly as a result of a cohort effect, with corresponding implications for prevention.

  13. Determination of GABA and vigabatrin in human plasma by a rapid and simple HPLC method: correlation between clinical response to vigabatrin and increase in plasma GABA.

    Science.gov (United States)

    Löscher, W; Fassbender, C P; Gram, L; Gramer, M; Hörstermann, D; Zahner, B; Stefan, H

    1993-03-01

    The novel antiepileptic drug vigabatrin (Sabril) acts by inhibiting degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), increasing the GABA concentrations in the brain. Because the GABA degrading enzyme GABA aminotransferase (GABA-T) is also present in peripheral tissues, including blood platelets, measurement of plasma GABA levels might be a useful indication of the pharmacological response to vigabatrin during therapeutic monitoring. However, because of the very low concentrations of GABA in plasma, the few methods available for plasma GABA analysis are time-consuming, difficult to perform and/or not selective enough because of potential interference with other plasma constituents. In the present study, a rapid, selective and sensitive amino acid analysis HPLC method has been developed for plasma GABA determination with fluorescence detection, using o-phthaldialdehyde as a precolumn derivatizing agent. By employing a 3 microns particle size reversed-phase column and a multi-step gradient system of two solvents, the very low endogenous concentration of GABA in human plasma could be reproducibly quantitated without interference of other endogenous compounds. Incubation of human plasma samples with GABA degrading enzyme(s) resulted in an almost total loss of the GABA peak, thus demonstrating the specificity of the method for GABA analysis. In addition to GABA and other endogenous amino acids, the HPLC method could be used to quantitate plasma levels of vigabatrin. Thus, this improved HPLC amino acid assay might be used to examine whether concomitant monitoring of plasma GABA and vigabatrin is useful for clinical purposes. This was examined in 20 epileptic patients undergoing chronic treatment with vigabatrin. The average plasma GABA level of these 20 patients did not differ significantly from non-epileptic controls. However, when epileptic patients were subdivided according to their clinical response to vigabatrin, vigabatrin responders

  14. Advertising representation, treatment menu and economic circulation of substance misuse treatment centers in Iran: a rapid survey based on newspaper advertisements.

    Science.gov (United States)

    Rezaee, Sobhan; Ekhtiari, Hamed

    2014-05-01

    Daily newspapers are the main platform by which substance misuse treatment (SMT) centers in Iran advertise their services. However, these advertisements provide little information on treatment options or costs. The current research aimed to use advertisements to compile a schema of treatment services and to map the extent and nature of drug treatments offered. During a four-week period (April to May) in 2009, the four most popular Persian newspapers printed in Tehran were reviewed. Across these publications 1704 advertisements were posted by 66 SMT centers. Each center was then contacted by telephone to complete a structured interview about services offered and related costs. The advertisements were also decoded through a quantitative contextual analysis method. On average, each SMT center published 26 advertisements during the review period, costing 421 US$. In addition, advertisements included word signifiers in six main categories including centers' introduction (100%), treatment types (91%), treatment duration (68%), medicines (70%), treatment features (60%) and psychological facilities (52%). The three detoxification programs advertised were the rapid method (57% of clinics, 443.23 US$), buprenorphine (68%, 265 US$) and methadone (71%, 137 US$). More than 90% of the centers in Tehran were offering methadone maintenance (99 US$, per month). SMT services in the Iranian market ranged from abstinence to maintenance programs, with opiates as the main focus. This review of centers' advertisements provides an indirect but rapidly obtained picture of the drug misuse treatment network. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. The economic case for low carbon waste management in rapidly growing cities in the developing world: The case of Palembang, Indonesia.

    Science.gov (United States)

    Papargyropoulou, Effie; Colenbrander, Sarah; Sudmant, Andrew Heshedahl; Gouldson, Andy; Tin, Lee Chew

    2015-11-01

    The provision of appropriate waste management is not only an indicator of development but also of broader sustainability. This is particularly relevant to expanding cities in developing countries faced with rising waste generation and associated environmental health problems. Despite these urgent issues, city authorities often lack the evidence required to make well-informed decisions. This study evaluates the carbon and economic performance of low-carbon measures in the waste sector at a city level, within the context of a developing country. Palembang in Indonesia is used as a case of a medium-sized city in a newly industrialized country, with relevance to other similar cities in the developing world. Evidence suggests that the waste sector can achieve substantial carbon emission reductions, and become a carbon sink, in a cost effective way. Hence there is an economic case for a low carbon development path for Palembang, and possibly for other cities in developing and developed countries facing similar challenges. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Applying economic incentives to increase effectiveness of an outpatient weight loss program (TRIO) - A randomized controlled trial.

    Science.gov (United States)

    Finkelstein, Eric A; Tham, Kwang-Wei; Haaland, Benjamin A; Sahasranaman, Aarti

    2017-07-01

    The prevalence of overweight and obesity has more than doubled in the past three decades, leading to rising rates of non-communicable diseases. This study tests whether adding a payment/rewards (term reward) program to an existing evidence-based weight loss program can increase weight loss and weight loss maintenance. We conducted a parallel-group randomized controlled trial from October 2012 to October 2015 with 161 overweight or obese individuals randomized to either control or reward arm in a 1:2 ratio. Control and reward arm participants received a four month weight loss program at the LIFE (Lifestyle Improvement and Fitness Enhancement) Centre at Singapore General Hospital. Those in the reward arm paid a fee of S$165.00 (1US$ = 1.35S$) to access a program that provided rewards of up to S$660 for meeting weight loss and physical activity goals. Participants could choose to receive rewards as guaranteed cash payments or a lottery ticket with a 1 in 10 chance of winning but with the same expected value. The primary outcome was weight loss at months 4, 8, and 12. 161 participants were randomized to control (n = 54) or reward (n = 107) arms. Average weight loss was more than twice as great in the reward arm compared to the control arm at month 4 when the program concluded (3.4 kg vs 1.4 kg, p rewards concluded (3.3 kg vs 1.8 kg, p rewards program can be used to improve weight loss and weight loss maintenance when combined with an evidence-based weight loss program. Future efforts should attempt to replicate this approach and identify how to cost effectively expand these programs to maximize their reach. This study is registered at www.clinicaltrials.gov (Identifier: NCT01533454). Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. The economic situation of large hydropower in Bavaria. Increasing burdens but dwindling revenues; Zur wirtschaftlichen Situation der grossen Wasserkraft in Bayern. Steigende Lasten - schwindende Erloese

    Energy Technology Data Exchange (ETDEWEB)

    Engels, Klaus; Gollum, Carsten [Uniper Kraftwerke GmbH, Landshut (Germany). Sparte Wasserkraft; Gruber, Karl Heinz [VERBUND Wasserkraft, Wien/Simbach/Toeging (Austria); Poehler, Frank [Bayerische Elektrizitaetswerke GmbH, Augsburg (Germany); Schleich, Albrecht [Rhein-Main-Donau AG, Muenchen (Germany)

    2016-11-01

    The current price development in the German electricity market results in significant economic challenges also for larger hydropower assets. Although an ideal partner for the transformation of the German energy system (''Energiewende''), the decline of electricity prices increasingly endangers adequate operations and sustainable investments, too. Hence, not only the renewable, emission-free, flexible and decentralised generation is questions but also multiple additional services for the society which are not remunerated by an ''energy only'' market. Price determination mechanisms as well as remunerations system in general need to be reviewed - an improvement of these structures is essential for larger hydropower assets.

  18. Rapid population growth.

    Science.gov (United States)

    1972-01-01

    At the current rate of population growth, world population by 2000 is expected to reach 7 billion or more, with developing countries accounting for some 5.4 billion, and economically advanced nations accounting for 1.6 billion. 'Population explosion' is the result of falling mortality rates and continuing high birth rates. Many European countries, and Japan, have already completed what is termed as demographic transition, that is, birth rates have fallen to below 20 births per 1000 population, death rates to 10/1000 population, and annual growth rates are 1% or less; annual growth rates for less developed countries ranged from 2 to 3.5%. Less developed countries can be divided into 3 groups: 1) countries with both high birth and death rates; 2) countries with high birth rates and low death rates; and 3) countries with intermediate and declining birth rates and low death rates. Rapid population growth has serious economic consequences. It encourages inequities in income distribution; it limits rate of growth of gross national product by holding down level of savings and capital investments; it exerts pressure on agricultural production and land; and it creates unemployment problems. In addition, the quality of education for increasing number of chidren is adversely affected, as high proportions of children reduce the amount that can be spent for the education of each child out of the educational budget; the cost and adequacy of health and welfare services are affected in a similar way. Other serious consequences of rapid population growth are maternal death and illness, and physical and mental retardation of children of very poor families. It is very urgent that over a billion births be prevented in the next 30 years to reduce annual population growth rate from the current 2% to 1% per year.

  19. An Asian dilemma. Modernising the electricity sector in China and India in the context of rapid economic growth and the concern for climate change

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, J.; Vlasblom, J.; Kroeze, C. (eds.)

    2001-12-01

    The research question dealt with in this report is: What are the feasible policy and technology options to modernise the electricity sector in China and India taking into account the supply and demand for electricity and given the conflict between the need for economic growth and the need to anticipate future developments in relation to the reduction of greenhouse gas emissions? The project essentially integrates three methodological approaches, a scenario approach, a bottom-up technology approach and an institutional cum stakeholder approach. Following an initial appraisal of the 'business-as-usual' scenario for the electricity sector for both countries, a range of policy and technology options was identified, as well as their potential and technical, economic and political feasibility. These options were combined and compared to the business-as-usual scenario to develop emission reduction scenarios for China and India and were tested with stakeholders to identify their feasibility and to assess the potential of using instruments at national and international level to facilitate their implementation. Although some measures have a high technical potential for reducing greenhouse gas emissions in both countries, these are not seen as particularly feasible by the stakeholders. For example end use efficiency has a very high technical emission to reduce emissions but is not given much priority in China and India (especially in the small-scale sector). Efficiency improvement in power plants and in transmission and distribution can also yield results in terms of emission reductions but are not seen as important in China. The report discusses the barriers and opportunities in relation to the various options. refs.

  20. Lactation curves and economic results of Saanen goats fed increasing dietary energy levels obtained by the addition of calcium salts of fatty acids

    Directory of Open Access Journals (Sweden)

    Rodrigo de Souza

    2014-02-01

    Full Text Available The objective of this study was to evaluate the use of calcium salts of fatty acids (CSFA to increase the dietary energy levels for Saanen goats and their effects on the lactation curve, dry matter intake, body weight, and economic results of the goats. Twenty multiparous goats, weighing an average of 63.5±10.3 kg, were randomly assigned to one of four treatment groups, each receiving one of the following dietary energy levels: a control diet consisting of 2.6 Mcal of metabolizable energy per kg of dry matter (Mcal ME/kg DM or a test diet supplemented with CSFA (Lactoplus® to obtain 2.7, 2.8, or 2.9 Mcal ME/kg DM. Goats were housed in individual stalls and were fed and milked twice daily. The animals were evaluated until 180 days in milk by measuring dry matter intake and milk yield. These measurements were used to calculate feed efficiencies and the cost-benefit ratio of diet and lactation curves using Wood's nonlinear model. Increasing dietary energy levels showed no effect on body weight. Supplementation with CSFA did not limit dry matter intake; however, it changed the shape of the lactation curve by promoting a late peak lactation with a longer duration. Milk yields at 180 days in milk had a quadratic increase with a maximum energy level at 2.85 Mcal ME/kg DM. Increasing the dietary energy level for Saanen goats using CSFA changes their lactation curves, with the best milk production achieved with a 2.85 Mcal ME/kg DM diet; however, the greatest economic results were obtained with a 2.7 Mcal ME/kg DM diet.

  1. Ecological economics and economic growth.

    Science.gov (United States)

    Victor, Peter A

    2010-01-01

    Boulding's 1966 paper on the economics of spaceship Earth established the framework for ecological economics and an understanding of economic growth. In ecological economics, economies are conceptualized as open subsystems of the closed biosphere and are subject to biophysical laws and constraints. Economic growth measured as an increase in real gross domestic product (GDP) has generally been associated with increases in the use of energy and materials and the generation of wastes. Scale, composition, and technology are the proximate determinants of environmental impacts. They are often reduced to two: scale (GDP) and intensity (impact per unit GDP). New work described in this paper defines "green" growth as intensity that declines faster than scale increases. Similarly, "brown" growth occurs when intensity declines more slowly than increases in scale, and "black" growth happens when both scale and intensity increase. These concepts are then related to the environmental Kuznets curve, which can be understood as a transition from brown to green growth. Ecological economics provides a macroperspective on economic growth. It offers broad policy principles, and it challenges the primacy of economic growth as a policy objective, but many important questions remain.

  2. Socio-economic status, lifestyle and childhood obesity in Gombe ...

    African Journals Online (AJOL)

    Background: Childhood obesity is a complex condition resulting from an interplay of genetic predisposition, environmental factors and socio-economic status. The prevalence has been increasing all over the world, probably due to economic transition and rapid urbanization as well as globalisation. This relationship should ...

  3. Impact of economic crisis on the intention to move house

    NARCIS (Netherlands)

    Dane, G.Z.; Grigolon, A.B.; Rasouli, S.; Timmermans, H.J.P.

    2016-01-01

    As a result of the economic crisis in 2008, the price of petrol, goods and agricultural products has rapidly increased and cities all over the world started to suffer from high levels of unemployment and lower business survival rates. Due to the economic downturn, the Dutch housing market also

  4. Impact of economic crisis on the intention to move house

    NARCIS (Netherlands)

    Dane, G.Z.; Grigolon, A.B.; Rasouli, S.; Timmermans, H.J.P.

    2014-01-01

    As a result of the economic crisis in 2008, the price of petrol, goods and agricultural products has rapidly increased and cities all over the world started to suffer from high levels of unemployment and lower business survival rates. Due to the economic downturn, the Dutch housing market also

  5. Improving early cycle economic evaluation of diagnostic technologies

    NARCIS (Netherlands)

    Steuten, Lotte Maria Gertruda; Ramsey, Scott D.

    2014-01-01

    The rapidly increasing range and expense of new diagnostics, compels consideration of a different, more proactive approach to health economic evaluation of diagnostic technologies. Early cycle economic evaluation is a decision analytic approach to evaluate technologies in development so as to

  6. Testing the effectiveness of in-home behavioral economics strategies to increase vegetable intake, liking, and variety among children residing in households that receive food assistance.

    Science.gov (United States)

    Leak, Tashara M; Swenson, Alison; Vickers, Zata; Mann, Traci; Mykerezi, Elton; Redden, Joseph P; Rendahl, Aaron; Reicks, Marla

    2015-01-01

    To test the effectiveness of behavioral economics strategies for increasing vegetable intake, variety, and liking among children residing in homes receiving food assistance. A randomized controlled trial with data collected at baseline, once weekly for 6 weeks, and at study conclusion. Family homes. Families with a child (9-12 years) will be recruited through community organizations and randomly assigned to an intervention (n = 36) or control (n = 10) group. The intervention group will incorporate a new behavioral economics strategy during home dinner meal occasions each week for 6 weeks. Strategies are simple and low-cost. The primary dependent variable will be child's dinner meal vegetable consumption based on weekly reports by caregivers. Fixed independent variables will include the strategy and week of strategy implementation. Secondary dependent variables will include vegetable liking and variety of vegetables consumed based on data collected at baseline and study conclusion. Mean vegetable intake for each strategy across families will be compared using a mixed-model analysis of variance with a random effect for child. In additionally, overall mean changes in vegetable consumption, variety, and liking will be compared between intervention and control groups. Copyright © 2015 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  7. The impact of the financial crisis under the effects of increasing global economic interdependence. The case of Eastern and Central Europe Economies

    Directory of Open Access Journals (Sweden)

    Bușega Ionuț

    2015-03-01

    Full Text Available The technological progress that arose in areas such as transportation, communication and information exchange has led to a series of consequences that forced national economies to converge into a global, market based economy. In addition to the aforementioned causes, increased liberalisation amidst financial markets has supplemented the initiation of this metamorphosis that had several benefits in terms of general commercial exchange (trade, capital flows, and investment opportunities for business organisations. Simultaneously with the financial leverage resulted from the expansion of these interconnections, a series of channels that are detrimental to the financial welfare of entities has emerged, which, in consequence elevated the vulnerability and susceptibility to external economic shocks. The major debate elicited by this trade-off mainly concerns the costs and benefits of the international liberalisation of capital flows and trade. The purpose of this article is to examine the methods through which globalisation has affected the expansion of the international financial crisis back in 2008, by identifying and assessing the subsequent transfer routes, to and from the United States, where it was initially triggered. This article also aims to evaluate the repercussions experienced by Central and Eastern Europe and how they re-established economic growth following the financial crisis.

  8. Use of extraction chromatography, ion chromatography and liquid scintillation spectrometry for rapid determination of strontium-89 and strontium-90 in food in cases of increased release of radionuclides

    International Nuclear Information System (INIS)

    Heilgeist, M.

    2000-01-01

    For rapid determination of 89 Sr and 90 Sr in food, isocratic ion chromatography used for Sr isolation and purification is integrated in a complete analytical system comprising sample preparation, incineration, dissolution, phosphate precipitation for alkali/alkaline earth separation, and Sr specific extraction chromatography on crown ether basis for Ca/Sr separation. Strontium-89 and 90 Sr are determined by liquid scintillation spectrometry after carbonate precipitation. The components of the mixed spectra obtained are calculated by the computerized spectra subtraction method. Two days plus measuring time are required for single, three for double analysis. The limit of detection for 89 Sr and 90 Sr is ca. 0.1 Bq x kg -1 , related to the fresh produce. (author)

  9. Can cognitive dissonance methods developed in the West for combatting the 'thin ideal' help slow the rapidly increasing prevalence of eating disorders in non-Western cultures?

    Science.gov (United States)

    Witcomb, Gemma L; Arcelus, Jon; Chen, Jue

    2013-12-01

    Eating disorders are common, life-threatening conditions in Western countries, but until relatively recently they were regarded as uncommon in non-Western cultures. However, the prevalence of eating disorders in many of the more affluent non-Western countries is rising rapidly as community members, particularly young women, internalize the 'thin ideal' that has been widely promoted by the international media. This review discusses the factors involved in the development of eating disorders in non-Western settings with a particular emphasis on the influences of urbanization, modernization, Westernization, and the resulting changes in women's roles. The cognitive dissonance programs developed in Western countries that have proven successful in countering the negative effects of the thin idea are described and their potential application to East Asia and other non-Western countries are discussed.

  10. The transgenerational effects of heat stress in the nematode Caenorhabditis remanei are negative and rapidly eliminated under direct selection for increased stress resistance in larvae.

    Science.gov (United States)

    Sikkink, Kristin L; Ituarte, Catherine M; Reynolds, Rose M; Cresko, William A; Phillips, Patrick C

    2014-12-01

    Parents encountering stress environments can influence the phenotype of their offspring in a form of transgenerational phenotypic plasticity that has the potential to be adaptive if offspring are thereby better able to deal with future stressors. Here, we test for the existence of anticipatory parental effects in the heat stress response in the highly polymorphic nematode Caenorhabditis remanei. Rather providing an anticipatory response, parents subject to a prior heat stress actually produce offspring that are less able to survive a severe heat shock. Selection on heat shock resistance within the larvae via experimental evolution leads to a loss of sensitivity (robustness) to environmental variation during both the parental and larval periods. Whole genome transcriptional analysis of both ancestor and selected lines shows that there is weak correspondence between genetic pathways induced via temperature shifts during parental and larval periods. Parental effects can evolve very rapidly via selection acting directly on offspring. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. The world energy demand in 2006: Confirmed increase in energy consumptions in a context of soaring crude oil prices; but economic growth is twice faster - June, 10 2007

    International Nuclear Information System (INIS)

    Chateau, Bertrand

    2007-01-01

    Confirmed increase in energy consumptions in a context of soaring crude oil prices; but economic growth is twice faster. According to the latest estimates by Enerdata, The world energy demand growth remains sustained in 2006, but twice slower than the GDP's growth, probably due to high energy prices on the international market. Oil: The oil demand, very captive, confirms once again its low elasticity to prices. 71% of the world oil product demand is concentrated on transport and petro-chemical sectors (77% in Europe, +13 points since 1990; 89% in North America). Gas/Electricity: Gas demand growth in 2006 is driven by Asia and the CIS, obvious price effects in the European Union. The CIS regains its position in the world production growth (22% in 2006 against 13% in 2005 and 33% in 2004). The power generation growth is more and more dominated by China and other Asian countries. The world electricity demand increases in the same proportions as in 2005 and 2004: 4%/year. Coal: Coal accounts for half of the world increase in energy consumption in 2006. China still accounts for 72% of the coal consumption, India for 10%, the rest of Asia 8% the rest of the world 10%. (authors)

  12. Modelling the implications of reducing smoking prevalence: the benefits of increasing the UK tobacco duty escalator to public health and economic outcomes.

    Science.gov (United States)

    Knuchel-Takano, Andre; Hunt, Daniel; Jaccard, Abbygail; Bhimjiyani, Arti; Brown, Martin; Retat, Lise; Brown, Katrina; Hinde, Sebastian; Selvarajah, Chit; Bauld, Linda; Webber, Laura

    2017-12-06

    Taxing tobacco is one of the most effective ways to reduce smoking prevalence, mitigate its devastating consequential health harms and progress towards a tobacco-free society. This study modelled the health and economic impacts of increasing the existing cigarette tobacco duty escalator (TDE) in the UK from the current 2% above consumer price inflation to 5%. A two-stage modelling process was used. First, a non-linear multivariate regression model was fitted to cross-sectional smoking data, creating longitudinal projections from 2015 to 2035. Second, these projections were used to predict the future incidence, prevalence and cost of 17 smoking-related diseases using a Monte Carlo microsimulation approach. A sustained increase in the duty escalator was evaluated against a baseline of continuing historical smoking trends and the existing duty escalator. A sustained increase in the TDE is projected to reduce adult smoking prevalence to 6% in 2035, from 10% in a baseline scenario. After increasing the TDE, only 65% of female and 60% of male would-be smokers would actually be smoking in 2035. The intervention is projected to avoid around 75 200 new cases of smoking-related diseases between 2015 and 2035. In 2035 alone, £49 m in National Health Service and social care costs and £192 m in societal premature mortality and morbidity costs are projected to be avoided. Increasing the UK TDE to 5% above inflation could effectively reduce smoking prevalence, prevent diseases and avoid healthcare costs. It would deliver substantial progress towards a tobacco-free society and should be implemented by the UK Government with urgency. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  13. The Impact of the Economic Transition on the Development of Economic Freedom – Case of Poland

    Directory of Open Access Journals (Sweden)

    Anna Stepniak-Kucharska

    2015-06-01

    Full Text Available The changes in the Polish socio-economic system, initiated at the turn of 1989 and 1990, led to a systematic increase in the liberalization of economy and thereby the rise of the level of economic freedom. The aim of this paper is to examine the impact of the economic transition on the development of economic freedom in Poland. The analysis, carried out in the period 1995-2015, was conducted on the basis of the chain-linked Economic Freedom Index by the Fraser Institute and the Index of Economic Freedom of the Heritage Foundation and the Wall Street Journal. The analysis indicates that: (1 Poland cannot be considered as a country that is fully free economically, but the transition of its economic system has resulted in a rapid growth of economic freedom. (2 The impact of transition varies for different areas (sub-indices of the economy. (3 The European economic integration stimulated the increase of EFI, but the economic crisis did not decrease the level of economic freedom.

  14. Rapid point-of-care CD4 testing at mobile HIV testing sites to increase linkage to care: an evaluation of a pilot program in South Africa.

    Science.gov (United States)

    Larson, Bruce A; Schnippel, Kathryn; Ndibongo, Buyiswa; Xulu, Thembisile; Brennan, Alana; Long, Lawrence; Fox, Matthew P; Rosen, Sydney

    2012-10-01

    A mobile HIV counseling and testing (HCT) program around Johannesburg piloted the integration of point-of-care (POC) CD4 testing, using the Pima analyzer, to improve linkages to HIV care. We report results from this pilot program for patients testing positive (n = 508) from May to October 2010. We analyzed 3 primary outcomes: assignment to testing group (offered POC CD4 or not), successful follow-up (by telephone), and completed the referral visit for HIV care within 8 weeks after HIV testing if successfully followed up. Proportions for each outcome were calculated, and relative risks were estimated using a modified Poisson approach. Three hundred eleven patients were offered the POC CD4 test, and 197 patients were not offered the test. No differences in patient characteristics were observed between the 2 groups. Approximately 62.7% of patients were successfully followed up 8 weeks after HIV testing, with no differences observed between testing groups. Among those followed up, 54.4% reported completing their referral visit. Patients offered the POC CD4 test were more likely to complete the referral visit for further HIV care (relative risk 1.25, 95% confidence interval: 1.00 to 1.57). In this mobile HCT setting, patients offered POC CD4 testing as part of the HCT services were more likely to visit a referral clinic after testing, suggesting that rapid CD4 testing technology may improve linkage to HIV care. Future research can evaluate options for adjusting HCT services if POC CD4 testing was included permanently and the cost-effectiveness of the POC CD4 testing compared with other approaches for improving linkage of care.

  15. Fluoroquinolone resistance mechanisms in urinary tract pathogenic Escherichia coli isolated during rapidly increasing fluoroquinolone consumption in a low-use country

    DEFF Research Database (Denmark)

    Christiansen, Nina; Nielsen, Lene; Jakobsen, Lotte

    2011-01-01

    Resistance to ciprofloxacin in Escherichia coli from urinary tract infections (UTI) in Denmark is increasing parallel to increased use of fluoroquinolones both in Denmark and in other European countries. The objective was to investigate the occurrence of ciprofloxacin resistance mechanisms......, phenotypic coresistance, and if ciprofloxacin resistance was caused by clonal spread or to individual mutational events in a collection of consecutively obtained E. coli submitted to a clinical microbiology department at a Danish hospital. One hundred four UTI-related E. coli resistant toward nalidixic acid...

  16. Profitability of a Smallholder Late Season Rapid Multiplication of ...

    African Journals Online (AJOL)

    The study investigated the effects of increasing poultry manure rates on the soil physicochemical properties, crop productivity and economic returns to investment of late season rapid multiplication of cassava stem enterprise at the Teaching and Research Farm, Federal University of Technology, Owerri in the humid ...

  17. Rapid Increase in Ownership and Use of Long-Lasting Insecticidal Nets and Decrease in Prevalence of Malaria in Three Regional States of Ethiopia (2006-2007

    Directory of Open Access Journals (Sweden)

    Estifanos Biru Shargie

    2010-01-01

    Full Text Available Following recent large scale-up of malaria control interventions in Ethiopia, this study aimed to compare ownership and use of long-lasting insecticidal nets (LLIN, and the change in malaria prevalence using two population-based household surveys in three regions of the country. Each survey used multistage cluster random sampling with 25 households per cluster. Household net ownership tripled from 19.6% in 2006 to 68.4% in 2007, with mean LLIN per household increasing from 0.3 to 1.2. Net use overall more than doubled from 15.3% to 34.5%, but in households owning LLIN, use declined from 71.7% to 48.3%. Parasitemia declined from 4.1% to 0.4%. Large scale-up of net ownership over a short period of time was possible. However, a large increase in net ownership was not necessarily mirrored directly by increased net use. Better targeting of nets to malaria-risk areas and sustained behavioural change communication are needed to increase and maintain net use.

  18. Localized infusions of the partial alpha 7 nicotinic receptor agonist SSR180711 evoke rapid and transient increases in prefrontal glutamate release

    DEFF Research Database (Denmark)

    Bortz, D M; Mikkelsen, J D; Bruno, J P

    2013-01-01

    The ability of local infusions of the alpha 7 nicotinic acetycholine receptor (α7 nAChR) partial agonist SSR180711 to evoke glutamate release in prefrontal cortex was determined in awake rats using a microelectrode array. Infusions of SSR180711 produced dose-dependent increases in glutamate levels...

  19. A surge of p-values between 0.041 and 0.049 in recent decades (but negative results are increasing rapidly too)

    Science.gov (United States)

    Dodou, Dimitra

    2015-01-01

    It is known that statistically significant (positive) results are more likely to be published than non-significant (negative) results. However, it has been unclear whether any increasing prevalence of positive results is stronger in the “softer” disciplines (social sciences) than in the “harder” disciplines (physical sciences), and whether the prevalence of negative results is decreasing over time. Using Scopus, we searched the abstracts of papers published between 1990 and 2013, and measured longitudinal trends of multiple expressions of positive versus negative results, including p-values between 0.041 and 0.049 versus p-values between 0.051 and 0.059, textual reporting of “significant difference” versus “no significant difference,” and the reporting of p 0.05. We found no support for a “hierarchy of sciences” with physical sciences at the top and social sciences at the bottom. However, we found large differences in reporting practices between disciplines, with p-values between 0.041 and 0.049 over 1990–2013 being 65.7 times more prevalent in the biological sciences than in the physical sciences. The p-values near the significance threshold of 0.05 on either side have both increased but with those p-values between 0.041 and 0.049 having increased to a greater extent (2013-to-1990 ratio of the percentage of papers = 10.3) than those between 0.051 and 0.059 (ratio = 3.6). Contradictorily, p 0.05 (ratios = 1.4 and 4.8, respectively), while the use of “significant difference” has shown only a modest increase compared to “no significant difference” (ratios = 1.5 and 1.1, respectively). We also compared reporting of significance in the United States, Asia, and Europe and found that the results are too inconsistent to draw conclusions on cross-cultural differences in significance reporting. We argue that the observed longitudinal trends are caused by negative factors, such as an increase of questionable research practices, but also by

  20. China's Economic Conditions

    National Research Council Canada - National Science Library

    Morrison, Wayne M

    2008-01-01

    ... (the fastest annual growth since 1994). While China is expected to continue to enjoy rapid economic growth in the years ahead and could become the world's largest economy within a decade or so, it faces a number of challenges, including...

  1. China's Economic Conditions

    National Research Council Canada - National Science Library

    Morrison, Wayne M

    2007-01-01

    .... China is expected to continue to enjoy rapid economic growth over the next several years, provided that it continues to implement needed reforms, particularly in regard to its inefficient state-owned...

  2. Are economic evaluations and health technology assessments increasingly demanded in times of rationing health services? The case of the Argentine financial crisis.

    Science.gov (United States)

    Rubinstein, Adolfo; Belizán, María; Discacciati, Vilda

    2007-01-01

    After 4 years of deepening recession, Argentina's economy plummeted after default in 2002. This crisis critically affected health expenditures and triggered acute rationing. Our objective was to explore health decision-makers' knowledge and attitudes about economic evaluations (EE) and whether health technology assessment (HTA) were increasingly used for decision making. A qualitative design based on semistructured interviews and focus groups was used to explore how decision makers belonging to different health sectors implement resource allocation decisions. Informants were mostly unaware of EE. The most important criteria mentioned to adopt a treatment were evidence of effectiveness, social/stakeholder demand, or resource availability. Despite general positive attitudes about EE, knowledge was rather limited. Although cost considerations were widely accepted by purchasers and managers, clinicians argued about these issues as interfering with the doctor-patient relationship. Other important perceived barriers to HTA use were lack of confidence in the transferability of studies conducted in developed countries and institutional fragmentation of the Argentine healthcare system. The new macroeconomic context was cited as a justification of implicit rationing measures. Although explicit priority setting was implemented by many purchasers and managers, HTA was not used to improve technical and/or allocative efficiency. The crisis seems to be a strong incentive to extend the use of HTA in Argentina, provided decision makers are aware as well as involved in the generation of local studies.

  3. Impaired left ventricular systolic function and increased brachial-ankle pulse-wave velocity are independently associated with rapid renal function progression.

    Science.gov (United States)

    Chen, Szu-Chia; Lin, Tsung-Hsien; Hsu, Po-Chao; Chang, Jer-Ming; Lee, Chee-Siong; Tsai, Wei-Chung; Su, Ho-Ming; Voon, Wen-Chol; Chen, Hung-Chun

    2011-09-01

    Heart failure and increased arterial stiffness are associated with declining renal function. Few studies have evaluated the association between left ventricular ejection fraction (LVEF) and brachial-ankle pulse-wave velocity (baPWV) and renal function progression. The aim of this study was to assess whether LVEFfunction was estimated by eGFR slope. The renal end point was defined as ≥25% decline in eGFR. Clinical and echocardiographic parameters were compared and analyzed. After a multivariate analysis, serum hematocrit was positively associated with eGFR slope, and diabetes mellitus, baPWV (P=0.031) and LVEFfunction decline and progression to the renal end point.

  4. Feeding Strategies Derived from Behavioral Economics and Psychology Can Increase Vegetable Intake in Children as Part of a Home-Based Intervention: Results of a Pilot Study.

    Science.gov (United States)

    Cravener, Terri L; Schlechter, Haley; Loeb, Katharine L; Radnitz, Cynthia; Schwartz, Marlene; Zucker, Nancy; Finkelstein, Stacey; Wang, Y Claire; Rolls, Barbara J; Keller, Kathleen L

    2015-11-01

    Behavioral economics and psychology have been applied to altering food choice, but most studies have not measured food intake under free-living conditions. To test the effects of a strategy that pairs positive stimuli (ie, stickers and cartoon packaging) with vegetables and presents them as the default snack. A randomized controlled trial was conducted with children who reported consumption of fewer than two servings of vegetables daily. Children (aged 3 to 5 years) in both control (n=12) and treatment (n=12) groups received a week's supply of plainly packaged (ie, generic) vegetables, presented by parents as a free choice with an alternative snack (granola bar), during baseline (Week 1) and follow-up (Week 4). During Weeks 2 and 3, the control group continued to receive generic packages of vegetables presented as a free choice, but the treatment group received vegetables packaged in containers with favorite cartoon characters and stickers inside, presented by parents as the default choice. Children in the treatment group were allowed to opt out of the vegetables and request the granola bar after an imposed 5-minute wait. General Linear Model repeated measures analysis of variance was conducted to compare vegetable and granola bar intake between control and treatment groups across the 4-week study. Both within- and between-subjects models were tested. A time×treatment interaction on vegetable intake was significant. The treatment group increased vegetable intake from baseline to Week 2 relative to control (Ppsychology in the home to increase children's vegetable intake and decrease intake of a high-energy-density snack. Additional studies are needed to test the long-term sustainability of these practices. Copyright © 2015 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  5. The mass spectrometry technology MALDI-TOF (Matrix-Assisted Laser Desorption/Ionization Time- Of-Flight for a more rapid and economic workflow in the clinical microbiology laboratory

    Directory of Open Access Journals (Sweden)

    Simona Barnini

    2012-12-01

    Full Text Available Introduction: In order to improve the outcome of patients, reduce length of stay, costs and resources engaged in diagnostics, more rapid reports are requested to the clinical microbiologists.The purpose of this study is to assess the impact on workflow of MALDI-TOF technology, recently made available for use in routine diagnostics. Methods:The work list by the management information system is sent to the instrument MALDI-TOF, where are held at least three successive analytic sessions: the first includes bacteria isolated from CSF, blood cultures, and cases already reported as serious/urgent, the second includes all other germs isolated, the third, microorganisms that require extraction with trifluoroacetic acid (TFA or formic acid (FA for identification.The results of each session direct to the execution of different types of susceptibility testing. Results:The times of microbial identifications are reduced by 24 or 48 hours and made available to the clinician for the rational empirical therapy.The reagent costs are reduced by 40%.The subcultures were reduced by 80%, and microscopic examinations by 50%.The antibiotic susceptibility tests were immediately performed with the most appropriate method, based on the knowledge of local epidemiology and microbial species. Conclusion:The bacteriology is the less automated discipline among the clinical laboratory activities and results of diagnostic tests are poorly well-timed. The new interpretative algorithms of MALDI-TOF spectra, now available, allow the correct identification of bacteria in near real time, completely eliminating the wait is necessary for biochemical identification and guiding the operator in selecting the most appropriate antibiotic susceptibility tests. This technology makes work more rapid, economic and efficient, eliminating errors and, together with effective computerization of data, transforms the information content of the microbiological report, making it much more effective

  6. Evaluation of the Implementation of a Rapid Response Treatment Protocol for Patients with Acute Onset Stroke: Can We Increase the Number of Patients Treated and Shorten the Time Needed

    Directory of Open Access Journals (Sweden)

    Rajiv Advani

    2014-06-01

    Full Text Available Aims: This study aims to evaluate the implementation of a rapid response treatment protocol for patients presenting with acute onset ischemic stroke. Improvements of routines surrounding the admission and treatment of patients with intravenous thrombolysis (IVT, such as door-to-needle (DTN times, and increasing the numbers of patients treated are discussed. Methods: We conducted a retrospective analysis of all patients (n = 320 treated with IVT for acute onset ischemic stroke at the Stavanger University Hospital, Norway, between 2003 and 2012. In 2009, a succession of changes to pre- and intra-hospital routines were made as well as an improvement in the education of primary health care physicians, nurses and paramedics involved in the treatment of acute onset stroke patients (rapid response treatment protocol. Analyses of DTN times, onset-to-needle times and the number of patients treated per year were carried out to ascertain the effect of the changes made. The primary aim was to analyze DTN times to look for any changes, and the secondary aim was to analyze changes in the number of patients treated per year. Results: In the years after the implementation of the rapid treatment protocol, we saw an improvement in the median DTN time with a decrease from 73 to 50 min in the first year (p = 0.03, a decrease of 45 min in the second year (p = 0.01 and a decrease of 31 min in the third year (p Conclusions: The implementation of the rapid treatment protocol for acute onset ischemic stroke patients led to a significant decrease in the DTN time at our center. These improvements also produced an increase in the number of patients treated per year. The extension of the therapeutic window from 3 to 4.5 h for the use of intravenous recombinant tissue plasminogen activator also played a role in the increased treatment numbers.

  7. Rapid Increase in Prevalence of Carbapenem-Resistant Enterobacteriaceae (CRE) and Emergence of Colistin Resistance Gene mcr-1 in CRE in a Hospital in Henan, China.

    Science.gov (United States)

    Li, Yi; Sun, Qiao-Ling; Shen, Yingbo; Zhang, Yangjunna; Yang, Jun-Wen; Shu, Ling-Bin; Zhou, Hong-Wei; Wang, Yang; Wang, Bing; Zhang, Rong; Wang, Shaolin; Shen, Zhangqi

    2018-04-01

    The global spread of carbapenem-resistant Enterobacteriaceae (CRE) is one of the most severe threats to human health in a clinical setting. The recent emergence of plasmid-mediated colistin resistance gene mcr-1 among CRE strains greatly compromises the use of colistin as a last resort for the treatment of infections caused by CRE. This study aimed to understand the current epidemiological trends and characteristics of CRE from a large hospital in Henan, the most populous province in China. From 2014 to 2016, a total of 7,249 Enterobacteriaceae isolates were collected from clinical samples, among which 18.1% (1,311/7,249) were carbapenem resistant. Carbapenem-resistant Klebsiella pneumoniae and carbapenem-resistant Escherichia coli were the two most common CRE species, with Klebsiella pneumoniae carbapenemases (KPC) and New Delhi metallo-β-lactamases (NDM), respectively, responsible for the carbapenem resistance of the two species. Notably, >57.0% ( n = 589) of the K. pneumoniae isolates from the intensive care unit were carbapenem resistant. Furthermore, bla NDM-5 and mcr-1 were found to coexist in one E. coli isolate, which exhibited resistance to almost all tested antibiotics. Overall, we observed a significant increase in the prevalence of CRE isolates during the study period and suggest that carbapenems may no longer be considered to be an effective treatment for infections caused by K. pneumoniae in the studied hospital. Copyright © 2018 American Society for Microbiology.

  8. Are Koreans Prepared for the Rapid Increase of the Single-Household Elderly? Life Satisfaction and Depression of the Single-Household Elderly in Korea

    Directory of Open Access Journals (Sweden)

    Mi-Ra Won

    2013-01-01

    Full Text Available Purpose. In Korea, it has been estimated that the number of the single-household elderly increased 45% from 2005 to 2010. This research was conducted to provide empirical resources for development of a community mental health program by an explorative investigation on depression, coping mechanism, and life satisfaction of a single-household elderly population. Design and Methods. This research applied a descriptive survey research design. Participants were 225 single-household elderlies residing in Seoul, Korea. The geriatric depression scale and the satisfaction with life scale were used to check the level of depression and life satisfaction of the participants. Results. Results showed that 46.3 percent of the participants were categorized as having light-to-severe level of depression, and 80.5 percent of the participants responded that they were dissatisfied with their lives. This research demonstrated that the level of depression and life satisfaction of the Korean single-household elderly is statistically significantly related to age and gender as well as coping resources and human resources. Implications. Current public health services in Korea for the single-household elderly are still lacking and require active support, intervention, and research to provide effective programs and services. Case management, counseling, and various programs based on Korean culture including support from family members and community-based assistance are recommended to help the vulnerable population.

  9. Numerical responses of saproxylic beetles to rapid increases in dead wood availability following geometrid moth outbreaks in sub-arctic mountain birch forest.

    Science.gov (United States)

    Vindstad, Ole Petter Laksforsmo; Schultze, Sabrina; Jepsen, Jane Uhd; Biuw, Martin; Kapari, Lauri; Sverdrup-Thygeson, Anne; Ims, Rolf Anker

    2014-01-01

    Saproxylic insects play an important part in decomposing dead wood in healthy forest ecosystems, but little is known about their role in the aftermath of large-scale forest mortality caused by pest insect outbreaks. We used window traps to study short-term changes in the abundance and community structure of saproxylic beetles following extensive mortality of mountain birch in sub-arctic northern Norway caused by an outbreak of geometrid moths. Three to five years after the outbreak, the proportion of obligate saproxylic individuals in the beetle community was roughly 10% higher in forest damaged by the outbreak than in undamaged forest. This was mainly due to two early-successional saproxylic beetle species. Facultative saproxylic beetles showed no consistent differences between damaged and undamaged forest. These findings would suggest a weak numerical response of the saproxylic beetle community to the dead wood left by the outbreak. We suggest that species-specific preferences for certain wood decay stages may limit the number of saproxylic species that respond numerically to an outbreak at a particular time, and that increases in responding species may be constrained by limitations to the amount of dead wood that can be exploited within a given timeframe (i.e. satiation effects). Low diversity of beetle species or slow development of larvae in our cold sub-arctic study region may also limit numerical responses. Our study suggests that saproxylic beetles, owing to weak numerical responses, may so far have played a minor role in decomposing the vast quantities of dead wood left by the moth outbreak.

  10. Numerical responses of saproxylic beetles to rapid increases in dead wood availability following geometrid moth outbreaks in sub-arctic mountain birch forest.

    Directory of Open Access Journals (Sweden)

    Ole Petter Laksforsmo Vindstad

    Full Text Available Saproxylic insects play an important part in decomposing dead wood in healthy forest ecosystems, but little is known about their role in the aftermath of large-scale forest mortality caused by pest insect outbreaks. We used window traps to study short-term changes in the abundance and community structure of saproxylic beetles following extensive mortality of mountain birch in sub-arctic northern Norway caused by an outbreak of geometrid moths. Three to five years after the outbreak, the proportion of obligate saproxylic individuals in the beetle community was roughly 10% higher in forest damaged by the outbreak than in undamaged forest. This was mainly due to two early-successional saproxylic beetle species. Facultative saproxylic beetles showed no consistent differences between damaged and undamaged forest. These findings would suggest a weak numerical response of the saproxylic beetle community to the dead wood left by the outbreak. We suggest that species-specific preferences for certain wood decay stages may limit the number of saproxylic species that respond numerically to an outbreak at a particular time, and that increases in responding species may be constrained by limitations to the amount of dead wood that can be exploited within a given timeframe (i.e. satiation effects. Low diversity of beetle species or slow development of larvae in our cold sub-arctic study region may also limit numerical responses. Our study suggests that saproxylic beetles, owing to weak numerical responses, may so far have played a minor role in decomposing the vast quantities of dead wood left by the moth outbreak.

  11. Modeling the economic dependence between town development policy and increasing energy effectiveness with neural networks. Case study: The town of Zielona Góra

    International Nuclear Information System (INIS)

    Skiba, Marta; Mrówczyńska, Maria; Bazan-Krzywoszańska, Anna

    2017-01-01

    Highlights: • Artificial neural networks (AI) are suitable to estimate the distribution of potential energy savings. • Improving the energy efficiency of buildings helps to reduce energy poverty. • Improving energy efficiency requires monitoring of estates and districts of cities. - Abstract: Due to the changes in legal requirements, growth of energy consumption from different media and prices increase it is necessary to change the attitude of urban consumers. Achieving the objectives of energy policy in each country requires societies to consolidate the confidence that reducing the demand for energy will pay to each household. Creating a positive investment climate, promoting new models and the dissemination of good examples can also lead to economic growth through the use of low-carbon technologies. In many countries, including Poland, the high energy intensity of buildings is seen as a result of the use of low quality materials, low constructing awareness causing the low standard of residential buildings, which is the reason for forcing thermal renovations. This article presents the distribution of market potential of savings for energy efficient renovations in construction on the example of a medium-sized city of Zielona Gora (Poland), which may be representative of cities in the country and in the world. The potential was determined on the basis of technology and a year of a construction of the buildings, technologies used, kind of development and dominating kind of heat and power supply. The calculated potential was presented as the value of the investments necessary to reduce energy consumption by 1 kW h/m"2. Artificial neural networks, which represent a sophisticated modeling technique and are among the computational intelligence methods were used to compute a distribution of potential. The article makes use of possibilities of multi-layer artificial neural networks trained by back propagation error technique and neural networks with radial basis

  12. Increases in CO2 from past low to future high levels result in “slower” strategies on the leaf economic spectrum

    NARCIS (Netherlands)

    Temme, Andries A.; Liu, Jin Chun; van Hal, Jurgen; Cornwell, Will K.; Cornelissen, Johannes (Hans) H.C.; Aerts, Rien

    2017-01-01

    Depending on resource availability plants exhibit a specific suite of traits. At the interspecific level these traits follow the leaf economic spectrum (LES), traits related to slow turnover when resources are poor and fast turnover when resources are plentiful. Limited data shows that within

  13. Increased Economic Relations Between China and Zambia in the Last Decade: Implications on Zambia’s Existing Bilateral Relations with the United States

    Science.gov (United States)

    2013-12-13

    political elites constitute a form of political embeddedness. Instead of engaging directly with affected parties, NFCA expects the Zambian government to...profits, but also how they make them. It goes beyond philanthropy and compliance and addresses how companies manage their economic, social, and

  14. Economic enterprise during economic dowturn

    Directory of Open Access Journals (Sweden)

    Eugeniusz Niedzielski

    2015-12-01

    The analysis showed, among others, that after a marked deterioration in the small and medium-sized enterprises sector in 2009 there was a gradual improvement of the financial situation and development of companies. Also, last year the level of optimism of entrepreneurs in the perception of the economic situation increased significantly.

  15. Neoclassical economic orthodoxy and the need for a new post-crisis economic paradigm

    Directory of Open Access Journals (Sweden)

    Andrei JOSAN

    2013-08-01

    Full Text Available Capitalism is a social adaptive system that evolve, change and grow in response to the challenges of a rapidly changing economic environment. When capitalism is seriously threatened by a systemic crisis, a new version much better adapted to existing conditions appears. Critical analysis of the fundamental ideas underlying neoclassical economic theory shows that the capitalist system is fundamentally a dynamic and therefore static neoclassical models proved to be unsuitable for studying it. Contrary to neoclassical economic vision, the capitalist economy is not governed by immutable economic laws. Global systemic crisis of capitalism that began in 2007 has highlighted the need for a new economic paradigm on which to be built and to be performed a new version of capitalism, in line with the increasingly complex realities of a globalized and quick changing world.

  16. Wind energy economics

    International Nuclear Information System (INIS)

    Milborrow, D.J.

    1995-01-01

    The economics of wind energy have improved rapidly in the past few years, with improvements in machine performance and increases in size both contributing to reduce costs. These trends are examined and future costs assessed. As bank loan periods for wind projects are shorter than for thermal plant, the effect on the price of wind energy is discussed. It is argued that wind energy has a higher value than that of centralised plant, since it is fed into the low voltage distribution network and it follows that the price of wind energy is converging with its value. The paper also includes a brief review of the capacity credit of wind plant and an assessment of the cost penalties which are incurred due to the need to hold extra plant on part load. These penalties are shown to be small. (author)

  17. Wind farm economics

    International Nuclear Information System (INIS)

    Milborrow, D.J.

    1995-01-01

    The economics of wind energy are changing rapidly, with improvements in machine performance and increases in size both contributing to reduce costs. These trends are examined and future costs assessed. Although the United Kingdom has regions of high wind speed, these are often in difficult terrain and construction costs are often higher than elsewhere in Europe. Nevertheless, wind energy costs are converging with those of the conventional thermal sources. At present, bank loan periods for wind projects are shorter than for thermal plant, which means that energy prices are higher. Ways of overcoming this problem are explored. It is important, also, to examine the value of wind energy. It is argued that wind energy has a higher value than energy from centralized plant, since it is fed into the low-voltage distribution network. (Author)

  18. An acute injection of corticosterone increases thyrotrophin-releasing hormone expression in the paraventricular nucleus of the hypothalamus but interferes with the rapid hypothalamus pituitary thyroid axis response to cold in male rats.

    Science.gov (United States)

    Sotelo-Rivera, I; Jaimes-Hoy, L; Cote-Vélez, A; Espinoza-Ayala, C; Charli, J-L; Joseph-Bravo, P

    2014-12-01

    The activity of the hypothalamic-pituitary-thyroid (HPT) axis is rapidly adjusted by energy balance alterations. Glucocorticoids can interfere with this activity, although the timing of this interaction is unknown. In vitro studies indicate that, albeit incubation with either glucocorticoid receptor (GR) agonists or protein kinase A (PKA) activators enhances pro-thyrotrophin-releasing hormone (pro-TRH) transcription, co-incubation with both stimuli reduces this enhancement. In the present study, we used primary cultures of hypothalamic cells to test whether the order of these stimuli alters the cross-talk. We observed that a simultaneous or 1-h prior (but not later) activation of GR is necessary to inhibit the stimulatory effect of PKA activation on pro-TRH expression. We tested these in vitro results in the context of a physiological stimulus on the HPT axis in adult male rats. Cold exposure for 1 h enhanced pro-TRH mRNA expression in neurones of the hypophysiotrophic and rostral subdivisions of the paraventricular nucleus (PVN) of the hypothalamus, thyrotrophin (TSH) serum levels and deiodinase 2 (D2) activity in brown adipose tissue (BAT). An i.p. injection of corticosterone stimulated pro-TRH expression in the PVN of rats kept at ambient temperature, more pronouncedly in hypophysiotrophic neurones that no longer responded to cold exposure. In corticosterone-pretreated rats, the cold-induced increase in pro-TRH expression was detected only in the rostral PVN. Corticosterone blunted the increase in serum TSH levels and D2 activity in BAT produced by cold in vehicle-injected animals. Thus, increased serum corticosterone levels rapidly restrain cold stress-induced activation of TRH hypophysiotrophic neurones, which may contribute to changing energy expenditure. Interestingly, TRH neurones of the rostral PVN responded to both corticosterone and cold exposure with an amplified expression of pro-TRH mRNA, suggesting that these neurones integrate stress and temperature

  19. Block chain Technology:Concept of Digital Economics

    OpenAIRE

    Ahmed, Ovais

    2017-01-01

    The purpose of the study is to explain about blockchain technology and how to use of blockchain technology for modern economics practices. We focused on this paper to put the light on blockchain usage in some other areas of economy such as, governance and political decision making, public finance, financial institution & stock market trading, global trading and other economic activities. The literature showed that blockchain is rapidly growing at globally and increasing digital money for tran...

  20. Consumption and environment - ecological economic perspectives

    DEFF Research Database (Denmark)

    Røpke, Inge

    2006-01-01

    motivation for dealing with consumption in ecological economics is presented. Basically, ecological economists agree that there are limits to the material growth of the economy, and that these limits have already been reached or exceeded. As there is an ethical challenge to increase environmental space......Consumption and environment – ecological economic perspectives Summary Research on issues related to consumption and environment has grown rapidly since the middle of the 1990s, and several disciplines as well as transdisciplinary fields have contributed to this development. The present papers...... constitute a small part of this wave of interest, and they are mostly framed as belonging to ecological economics. The collection starts with an introduction to the field of consumption research within ecological economics and then follows a series of papers on more specific issues. The introductionary...

  1. Multidetector-row CT: economics and workflow

    International Nuclear Information System (INIS)

    Pottala, K.M.; Kalra, M.K.; Saini, S.; Ouellette, K.; Sahani, D.; Thrall, J.H.

    2005-01-01

    With rapid evolution of multidetector-row CT (MDCT) technology and applications, several factors such ad technology upgrade and turf battles for sharing cost and profitability affect MDCT workflow and economics. MDCT workflow optimization can enhance productivity and reduce unit costs as well as increase profitability, in spite of decrease in reimbursement rates. Strategies for workflow management include standardization, automation, and constant assessment of various steps involved in MDCT operations. In this review article, we describe issues related to MDCT economics and workflow. (orig.)

  2. Community Economics

    OpenAIRE

    武藤, 宣道; Nobumichi, MUTOH

    2000-01-01

    This paper examines the new field of community economics with respect to Japan. A number of studies in community economics have already been produced in OECD countries including the United States. Although these are of great interest, each country has its own historical, socioeconomic context and must therefore develop its own approach to community economics. Community-oriented economics is neither macro-nor micro-economics in the standard economics textbook sense. Most community economics st...

  3. What factors are associated with increasing co-authorship in the social sciences? A case study of Danish Economics and Political Science

    DEFF Research Database (Denmark)

    Henriksen, Dorte

    2018-01-01

    these changes. This article examines the relationship between changes in co-authorship and research in Danish economics and political science to gain greater insights into whether there are changes in the research or in researchers' behavior. The analysis shows that articles with empirical research......The number of co-authors has in the social sciences has been rising over the last decades, but a deeper understanding of why this rise is occurring is lacking. Previous studies of co-authorship in the social sciences often refer to the physical or life sciences or anecdotal evidence to explain......, quantitative research and/or survey are more likely to have a higher number of coauthors than articles based on theoretical, interview, and qualitative research. Furthermore, international and interinstitutional Danish articles tend to have more coauthors than interinstitutional articles. The analysis also...

  4. Intimate partner violence and symptoms of sexually transmitted infections: are the women from low socio-economic strata in Bangladesh at increased risk.

    Science.gov (United States)

    Rahman, Mosiur; Nakamura, Keiko; Seino, Kaoruko; Kizuki, Masashi

    2014-04-01

    There is little research on whether women who are either poor or illiterate and have experienced intimate partner violence (IPV) have a unique risk of sexually transmitted infections (STIs). Most such research concerns families displaced by wars and conflicts. Therefore, we aimed to further this important area of inquiry by (1) addressing whether an association exists between experiences of physical and/or sexual IPV within the past year and symptoms of STI and (2) exploring the relationship between low socio-economic status and IPV and the relative roles they play as obstacles to reducing women's risk of STI in a nationally representative sample of Bangladesh. This paper used data from the 2007 Bangladesh Demographic Health Survey. The analyses were based on the responses of 4,195 currently married women. Exposure was determined from women's experiences of physical and sexual IPV within the past year. Genital sores and genital discharge were used as proxy outcome variables of the symptoms of STI. Descriptive statistics and multivariate logistic regression analysis were used in the study. Experience of any physical and/or sexual IPV were associated with genital sores (adjusted odds ratio [AOR] = 1.79; 95 % confidence interval [CI], 1.28-2.51) and genital discharge (AOR 1.90, 95 % CI 1.42-2.53). Severity of physical IPV appeared to have more profound consequences on the outcome measured. Findings also demonstrated that for the risk of STI, women at the nexus of poverty or illiteracy and IPV were not more uniquely disadvantaged. The results suggest that for the risk of STI, the negative effect of having experienced IPV extends across all socio-economic backgrounds and is not limited to women at either at the nexus of poverty or illiteracy and IPV. Findings underscore the calls for protecting women from all forms of physical and sexual violence from their husbands as a part of interventions to reduce the risk of STI.

  5. Economic Effect on the Plutonium Cycle of Employing {sup 235}U in Fast Reactor Start-Up; Incidence Economique du Demarrage des Reacteurs Rapides a l'Aide d'Uranium-235 sur le Cycle du Plutonium

    Energy Technology Data Exchange (ETDEWEB)

    Van Dievoet, J.; Egleme, M.; Hermans, L. [BELGONUCLEAIRE, Bruxelles (Belgium)

    1967-09-15

    Preliminary results are presented of a study carried out under an agreement concluded between Euratom and the Belgian Government to evaluate the advantages of loading fast reactors with {sup 235}U. There are several ways of starting up a fast reactor with {sup 235}U: (1) the reactor can be operated entirely with enriched uranium, the plutonium produced being used to start up and operate other reactors; in this case the uranium is recycled within the reactor and more enriched uranium is added; (2) the plutonium produced can be partly recycled within the reactor together with the uranium; in this case the reactor is transformed gradually into a plutonium reactor. These two procedures can be combined and applied simultaneously in different enrichment zones of the same reactor, enriched uranium being added, for example, to the internal zone and plutonium recycled in the external zone. The method of reprocessing the fuel is also a complicating factor, depending on whether the core and the axial breeding blankets are reprocessed together or separately. Similarly, where a reactor has several enrichment zones, these can likewise be reprocessed either together or separately. The calculations are performed with the help of a code that uses the equivalence coefficients defined by Baker and Ross for the part relating to the characteristics of successive reactors, and the discounted fuel cycle cost method for the economic part. In the first stage of this work a rough analysis was made. The reloading of each zone was assumed to be carried out in a single operation, and the time spent by the fuel elements out of pile was ignored. In a later stage, progressive reloading by batches will be considered, with allowance for fabrication and reprocessing times, etc. The most interesting results relate to variations in fuel composition (plutonium content, isotopic composition) from one cycle to another, variations in the fuel cycle characteristics (doubling time, loading and unloading

  6. Space and economics

    NARCIS (Netherlands)

    Klijs, Jeroen; Heijman, Wim J.M.; Peerlings, Jack H.M.; Rouwendal, Jan; Schipper, Rob A.

    2017-01-01

    The subject area Regional Economics has become topical. This means that in economic analyses the production factor 'space' is of increasing importance. This study book aims to integrate space in the area of General Economics in an analytical way. Models and their applications play a major role in

  7. Population and economics.

    Science.gov (United States)

    Wright, W

    1995-06-01

    The first world consists of the developed industrial countries, the second consists of rapidly developing countries, and the third of less developed, largely pre-industrial countries. The economies of most developed countries in recent years have been relatively stagnant. Most people in the developed world therefore assume that the bottom of the business cycle has arrived and that an upturn will soon be forthcoming. With the exception of the USA and Chile, which have been moderately prosperous in the last few years, the bottom has persisted for a very long time. Indeed, the developed world is not caught in a conventional business cycle, but in something quite new and different. The first world is struggling to stay at the top of countries worldwide both economically and politically, but the second world is rapidly catching up. Populations in these latter countries are both better educated and willing to work harder per unit of capital compared to people in the first world. Marketplace forces and the communication highway are increasingly bring about a scenario in which the first and second worlds will be economic peers. Faced with increased competition from the second world and a larger number of countries capable of providing foreign aid to the third world, it should be clear that the first world will turn inward and reduce its annual aid contributions to less developed countries. It is, however, in the first world's interest to promote family planning toward the goal of reduced population growth. Developed countries should insist that a substantial fraction of whatever foreign aid is provided goes toward reducing the rate of population growth. The first priority should be to make contraceptives available and promote their use worldwide. Efforts should then be taken to empower women through educational and other programs. This approach will slow population growth and improve the economic productivity of both men and women. The Third World should also seriously

  8. Development Center for Digital Government Cooperation Patterns of Small Medium Enterprises-Private to the Acceleration of Economic Increase in Tourist Areas

    OpenAIRE

    Suyono, Joko; Sudapet, Nyoman

    2017-01-01

    The infrastructure budget reached Rp 290 Billion in APBN-P (Budget spending Revenue State changes) in 2015 be consist of opportunities for investors and Government Areas, this will be trigger an increase in the central area of UKM. 2014 year Indonesia stock exchange noted the value of market capitalization (market cap) to the property sector, real estate, and construction of the building reached Rp 360 Billion (idx, 2014). Bank Indonesia survey showed a significant increase in the selling pri...

  9. Economic impact of GM crops

    Science.gov (United States)

    Brookes, Graham; Barfoot, Peter

    2014-01-01

    A key part of any assessment of the global value of crop biotechnology in agriculture is an examination of its economic impact at the farm level. This paper follows earlier annual studies which examined economic impacts on yields, key costs of production, direct farm income and effects, and impacts on the production base of the four main crops of soybeans, corn, cotton and canola. The commercialization of genetically modified (GM) crops has continued to occur at a rapid rate, with important changes in both the overall level of adoption and impact occurring in 2012. This annual updated analysis shows that there have been very significant net economic benefits at the farm level amounting to $18.8 billion in 2012 and $116.6 billion for the 17-year period (in nominal terms). These economic gains have been divided roughly 50% each to farmers in developed and developing countries. GM technology have also made important contributions to increasing global production levels of the four main crops, having added 122 million tonnes and 230 million tonnes respectively, to the global production of soybeans and maize since the introduction of the technology in the mid-1990s. PMID:24637520

  10. Analyzing suitability for urban expansion under rapid coastal urbanization with remote sensing and GIS techniques: a case study of Linanyungang, China

    DEFF Research Database (Denmark)

    Zhao, Wenjun; Zhu, Xiaodong; Reenberg, Anette

    2010-01-01

    Beginning in 2000, Lianyungang's urbanization entered a period of rapid growth, spatially as well as economically. Rapid and intensive expansion of "construction land" imposed increasing pressures on regional environment. With the support of remote sensing data and GIS tools, this paper reports a...

  11. China's Economic Conditions

    National Research Council Canada - National Science Library

    Morrison, Wayne M

    2008-01-01

    ... (the fastest annual growth since 1994). While China is expected to continue to enjoy rapid economic growth in the years ahead and could become the world s largest economy within a decade or so, it faces a number of challenges, including...

  12. Economics of nuclear and renewables

    International Nuclear Information System (INIS)

    Khatib, Hisham; Difiglio, Carmine

    2016-01-01

    This paper provides an assessment of the economic challenges faced by both nuclear power and “new” renewable electricity technologies. The assessment reflects the need to incorporate new renewables into power grids and issues faced in dispatching power and their effect on traditional electricity technologies as well as the need for transmission extension and/or grid reinforcement. Wider introduction of smart grids and the likely demise of nuclear in some OECD countries are bound to enhance the future prospects for new renewables. However, their immediate future expansion will depend on continued subsidies, which are becoming difficult to sustain in present economic circumstances. Development of large energy storage facilities and carbon pricing could significantly enhance future renewable energy prospects. Correspondingly, expanding renewable energy, in spite of their popularity with some governments and sections of the public, is likely to face challenges which will slow their present rapid progress. Nuclear is now shied away from in many industrialized countries and having mixed prospects in developing economies. In many instances, it suffers from high initial costs, long lead times and often excessive construction delays. Nuclear power also faces challenging risks – investment as well as regulatory. In contrast to renewables, its share of global energy consumption is declining. - Highlights: •Renewables are increasing their energy share. •Renewables system cost is higher than their production cost. •Nuclear share is not increasing and their costs are not reduced. •Discount rate and subsidies are important in economics of renewables and nuclear.

  13. Rapid Geophysical Surveyor

    International Nuclear Information System (INIS)

    Roybal, L.G.; Carpenter, G.S.; Josten, N.E.

    1993-01-01

    The Rapid Geophysical Surveyor (RGS) is a system designed to rapidly and economically collect closely-spaced geophysical data used for characterization of US Department of Energy waste sites. Geophysical surveys of waste sites are an important first step in the remediation and closure of these sites; especially older sites where historical records are inaccurate and survey benchmarks have changed because of refinements in coordinate controls and datum changes. Closely-spaced data are required to adequately differentiate pits, trenches, and soil vault rows whose edges may be only a few feet from each other. A prototype vehicle designed to collect magnetic field data was built at the Idaho National Engineering Laboratory (INEL) during the summer of 1992. The RGS was funded by the Buried Waste Integrated Demonstration program. This vehicle was demonstrated at the Subsurface Disposal Area (SDA) within the Radioactive Waste Management Complex at the INEL in September 1992. Magnetic data were collected over two areas in the SDA, with a total survey area of about 1.7 acres. Data were collected at a nominal density of 2 1/2 in. along survey lines spaced 1-ft apart. Over 350,000 data points were collected over a 6 day period corresponding to about 185 worker-days using conventional ground survey techniques

  14. Economic growth of the United States: perspective and prospective. [Monograph

    Energy Technology Data Exchange (ETDEWEB)

    Fabricant, S

    1979-01-01

    A post-World War II analysis of the potential for US economic expansion projects a continuation of the basic social and economic expectations and international relations and of the upward trend of labor input, labor productivity, and national output. How economic growth of the future will differ as a result of global changes in population and resources is examined in the context of other national objectives. The rapid increase in labor productivity during the postwar period was taken in the form of income rather than leisure. This led to a growth of goods and real per capita income as well as higher standards of living, education, and economic stability. The implications for future growth indicate the need to slow the growth of the national product in line with the rate of population growth. The improved welfare of the people should be the overall goal of which economic growth is one component. 23 tables. (DCK)

  15. Bifurcations of a class of singular biological economic models

    International Nuclear Information System (INIS)

    Zhang Xue; Zhang Qingling; Zhang Yue

    2009-01-01

    This paper studies systematically a prey-predator singular biological economic model with time delay. It shows that this model exhibits two bifurcation phenomena when the economic profit is zero. One is transcritical bifurcation which changes the stability of the system, and the other is singular induced bifurcation which indicates that zero economic profit brings impulse, i.e., rapid expansion of the population in biological explanation. On the other hand, if the economic profit is positive, at a critical value of bifurcation parameter, the system undergoes a Hopf bifurcation, i.e., the increase of delay destabilizes the system and bifurcates into small amplitude periodic solution. Finally, by using Matlab software, numerical simulations illustrate the effectiveness of the results obtained here. In addition, we study numerically that the system undergoes a saddle-node bifurcation when the bifurcation parameter goes through critical value of positive economic profit.

  16. Rapid thermal conditioning of sewage sludge

    Science.gov (United States)

    Zheng, Jianhong

    Rapid thermal conditioning (RTC) is a developing technology recently applied to sewage sludge treatment. Sludge is heated rapidly to a reaction temperature (up to about 220sp°C) under sufficient pressure to maintain the liquid phase. Reaction is quenched after 10 to 30 seconds when the mixture of sludge and steam pass through a pressure let-down valve. This process reduces the amount of sludge requiring land disposal, eliminates the need for polymer coagulant, improves dewaterability, increases methane production, and further reduces the concentration of pathogens. The odor problem associated with traditional thermal conditioning processes is largely minimized. Ammonia removal is readily integrated with the process. For this research, a pilot unit was constructed capable of processing 90 liters of sludge per hour. Over 22 runs were made with this unit using sludge from New York City Water Pollution Control Plants (WPCP). Sludges processed in this equipment were tested to determine the effect of RTC operating conditions on sludge dewaterability, biodegradability, and other factors affecting the incorporation of RTC into wastewater treatment plants. Dewaterability of thermally conditioned sludge was assessed for cetrifugeability and filterability. Bench scale centrifugation was used for evaluating centrifugeability, pressure filtration and capillary suction time (CST) for filterability. A mathematical model developed for centrifuge dewatering was used to predict the effect of RTC on full scale centrifuge performance. Particle size distribution and solids density of raw and treated PDS were also analyzed. An observed increase in sludge solids density at least partially explains its improved centrifugeability. An investigation of thermally conditioned amino acids showed that the L-isomer is highly biodegradable while the D-isomers are generally less so. Glucose is highly biodegradable, but rapidly becomes refractory as thermal conditioning time is lengthened. This

  17. The antidepressant agomelatine blocks the adverse effects of stress on memory and enables spatial learning to rapidly increase neural cell adhesion molecule (NCAM) expression in the hippocampus of rats.

    Science.gov (United States)

    Conboy, Lisa; Tanrikut, Cihan; Zoladz, Phillip R; Campbell, Adam M; Park, Collin R; Gabriel, Cecilia; Mocaer, Elisabeth; Sandi, Carmen; Diamond, David M

    2009-04-01

    Agomelatine, a novel antidepressant with established clinical efficacy, acts as a melatonin receptor agonist and 5-HT(2C) receptor antagonist. As stress is a significant risk factor in the development of depression, we sought to determine if chronic agomelatine treatment would block the stress-induced impairment of memory in rats trained in the radial-arm water maze (RAWM), a hippocampus-dependent spatial memory task. Moreover, since neural cell adhesion molecule (NCAM) is known to be critically involved in memory consolidation and synaptic plasticity, we evaluated the effects of agomelatine on NCAM, and polysialylated NCAM (PSA-NCAM) expression in rats given spatial memory training with or without predator stress. Adult male rats were pre-treated with agomelatine (10 mg/kg i.p., daily for 22 d), followed by a single day of RAWM training and memory testing. Rats were given 12 training trials and then they were placed either in their home cages (no stress) or near a cat (predator stress). Thirty minutes later the rats were given a memory test trial followed immediately by brain extraction. We found that: (1) agomelatine blocked the predator stress-induced impairment of spatial memory; (2) agomelatine-treated stressed, as well as non-stressed, rats exhibited a rapid training-induced increase in the expression of synaptic NCAM in the ventral hippocampus; and (3) agomelatine treatment blocked the water-maze training-induced decrease in PSA-NCAM levels in both stressed and non-stressed animals. This work provides novel observations which indicate that agomelatine blocks the adverse effects of stress on hippocampus-dependent memory and activates molecular mechanisms of memory storage in response to a learning experience.

  18. Economic development and road traffic fatalities in two neighbouring African nations

    Directory of Open Access Journals (Sweden)

    Douglas J. Wiebe

    2016-06-01

    Conclusion: Road crash fatalities increased in recent decades in both Zambia and Botswana. But the rapid economic development in Botswana over this time period appears to have driven proportionate road traffic fatality increases. There are opportunities for newly emerging economies such as Zambia, Angola, and others to learn from the Botswana experience. Evidence-based investments in road safety interventions should be concomitant with economic development.

  19. The way to improve the quality of domestic shipbuilding and ship repair for increasing economic presence of Russia in the Arctic

    Directory of Open Access Journals (Sweden)

    Semenov V. P.

    2016-06-01

    Full Text Available The main problems and ways to improve the efficiency and quality of military shipbuilding and ship repair in modern conditions have been presented. The necessity for state support of shipbuilding and ship repair and development of entrepreneurship in the industry has been pointed out; a number of modern ways of increasing the efficiency and quality of management has been defined. Представлены основные проблемы и направления повышения эффективности и качества военного судостроения и судоремонта в современных условиях. В контексте решения проблем выделена необходимость обеспечения государственной поддержки судостроения и судоремонта, развития предпринимательства в отрасли, определен ряд современных направлений повышения эффективности и развития менеджмента качества

  20. Economic Theory, Economic Reality And Economic Policy

    Directory of Open Access Journals (Sweden)

    Dmitry Evgenievich Sorokin

    2015-03-01

    Full Text Available This paper analyzes the opposition between the «liberals» and «statists» in the Russian political and economic thought. It demonstrates that the economic liberalization is an absolute prerequisite for the transition to sustainable socio-economic development. Such development must rely on investment activities of the state, which in the current circumstances is a necessary but not sufficient measure for reversing the negative trends. The negative developments can be prevented only through implementation, along with the institutional changes in the economic area that form a strata of economically independent entrepreneurs-innovators, of no less profound transformation in political institutions aimed at democratization of public life

  1. Internet economics

    DEFF Research Database (Denmark)

    Henten, Anders; Skouby, Knud Erik; Øst, Alexander Gorm

    1997-01-01

    A paper on the economics of the Internet with respect to end user pricing and pricing og interconnect.......A paper on the economics of the Internet with respect to end user pricing and pricing og interconnect....

  2. Energy economics

    Energy Technology Data Exchange (ETDEWEB)

    Develi, Abdulkadir; Kaynak, Selahattin (eds.)

    2012-07-01

    Energy resources, the basic input in every area of the economy, have a fundamental function for society's welfare. Traditional energy resources are, however, rapidly decreasing. Energy supply has been falling behind in meeting global demand, and is causing increased focus on efficiency and economy concepts in recent energy policies. Since the existing energy resources are not spread evenly among the countries, but instead are concentrated in certain regions and countries, a monopolistic situation arises. Equally, supply assurance is an issue, since the energy supply is held by certain regions and countries who have monopolistic pricing power. Both the EU and many other countries are studying how to marketize energy. This book focuses on the importance of energy and the problems posed by it. It will be useful for the academic community, related sectors and decision makers.

  3. Economic Development

    Science.gov (United States)

    Recruitment Events Community Commitment Giving Campaigns, Drives Economic Development Employee Funded : Environmental Documents, Reports LANL Home Calendar Search Contacts Community » Economic Development LANL 75th logo Economic Development Los Alamos National Laboratory is committed to investing and partnering in

  4. STYLIZED ECONOMIC FACTS OF TRANSITION

    Directory of Open Access Journals (Sweden)

    NATASHA TRAJKOVA-NAJDOVSKA

    2017-12-01

    Full Text Available In the course of transition, former socialistic countries moved from planned to market economy. This journey typically started with sharp falls in economic activity in all transition countries, accompanied by deterioration of various social indicators. Hence, their main objective was the recovery of economic activity, i.e. increasing the economic growth rate, which in addition was supposed to enable catching up with the European developed economies. This growth movement is usually described by famous U-curve of transition. However, in spite of the efforts and reforms, all transition economies recorded various paces of recovery. This study discusses that difference, through various GDP indicators, - real GDP path, GDP growth rates path, the height of the GDP index achieved and the volatility of growth rates. Analysed in concert, these indicators suggest several other variations of the transition Ucurve, such as: the rapid-J group, the wide-U group and the L-curve group. Namely, almost three decades after the start of the transition, the differences persist, suggesting that some transition economies has not moved significantly towards catching up with the successful transition countries, or with the developed economies.

  5. Economics Aspects of Increasing the Oil Price

    Directory of Open Access Journals (Sweden)

    Grendel Peter

    2004-09-01

    Full Text Available In paper I describe mainly high price of oil, which has influence on many circumstances. The important effect on growing up the price of oil has situation in Mid-east, and everyday rising consumption of oil in China. Meaningful position have USA, which using 45% of word energy. The problem is particularly in daily mining of lode. In next part i describing aspect of this situation on stock-exchange, mainly behaviour of speculators, and OPEC, and also presure on inflation in Euro-zone. In the last chapter I discuss about reaction of the big world oil concern like CONOCO, SHELL, BP, OMV and MOL.

  6. Economic consequences of increased bioenergy demand

    NARCIS (Netherlands)

    Johnston, C.; Kooten, van G.C.

    2014-01-01

    Although wind, hydro and solar are the most discussed sources of renewable energy, countries will need to rely much more on biomass if they are to meet renewable energy targets. In this study, a global forest trade model is used to examine the global effects of expanded demand for wood pellets fired

  7. Perspectives of economics – behavioural economics

    Directory of Open Access Journals (Sweden)

    Paula-Elena DIACON

    2013-07-01

    Full Text Available The present turning point, accentuated by the crisis, has revitalized the interdisciplinary study of economics and determined the reconsideration of its fundamental bases as a social science. The economists have abandoned the traditional neoclassical sphere and have directed towards understanding the behaviour resorting to psychology and developing in this manner a new field - behavioural economics. This article examines whether this economic sub-discipline is a viable research direction and the extent to which it may increase the explanatory power of science by providing a realistic database for analysis, taking into account the complexity of the human factor.

  8. Rapid shallow breathing

    Science.gov (United States)

    Tachypnea; Breathing - rapid and shallow; Fast shallow breathing; Respiratory rate - rapid and shallow ... Shallow, rapid breathing has many possible medical causes, including: Asthma Blood clot in an artery in the ...

  9. Economics-driven software architecture

    CERN Document Server

    Mistrik, Ivan; Kazman, Rick; Zhang, Yuanyuan

    2014-01-01

    Economics-driven Software Architecture presents a guide for engineers and architects who need to understand the economic impact of architecture design decisions: the long term and strategic viability, cost-effectiveness, and sustainability of applications and systems. Economics-driven software development can increase quality, productivity, and profitability, but comprehensive knowledge is needed to understand the architectural challenges involved in dealing with the development of large, architecturally challenging systems in an economic way. This book covers how to apply economic consider

  10. The ethics and economics of pharmaceutical pricing.

    Science.gov (United States)

    Parker-Lue, Sara; Santoro, Michael; Koski, Greg

    2015-01-01

    The cost of drugs is a major and rapidly rising component of health-care expenditures. We survey recent literature on the ethics and economics of skyrocketing pharmaceutical prices and find that advances in economic research have increased the sharpness and focus of the ethically based calls to increase access by modifying patent protection and reducing prices. In some cases, research supports ethical arguments for broader access. Other research suggests that efforts to broaden access result in unintended consequences for innovation and the medical needs of patients. Both ethicists and economists need to be more cognizant of the real clinical settings in which physicians practice medicine with real patients. Greater cross-disciplinary interaction among economists, ethicists, and physicians can help reduce the disjunction between innovation and access and improve access and patient care. This dialogue will impact private industry and may spur new multistakeholder paradigms for drug discovery, development, and pricing.

  11. Economic Studies

    Directory of Open Access Journals (Sweden)

    A. V. Kholopov

    2014-01-01

    Full Text Available The establishment of the School of Economic Science at MGIMO was due to the necessity of the world economy research, and the need to prepare highly skilled specialists in international economics. The school is developing a number of areas, which reflect the Faculty structure. - Economic theory is one of the most important research areas, a kind of foundation of the School of Economic Science at MGIMO. Economic theory studies are carried out at the chair of Economic theory. "The course of economic theory" textbook was published in 1991, and later it was reprinted seven times. Over the past few years other textbooks and manuals have been published, including "Economics for Managers" by Professor S.N. Ivashkovskaya, which survived through five editions; "International Economics" - four editions and "History of Economic Thought" - three editions. - International Economic Relations are carried out by the Department of International Economic Relations and Foreign Economic Activity. Its establishment is associated with the prominent economist N.N. Lyubimov. In 1957 he with his colleagues published the first textbook on the subject which went through multiple republications. The editorial team of the textbook subsequently formed the pride of Soviet economic science - S.M. Menshikov, E.P. Pletnev, V.D. Schetinin. Since 2007, the chair of Foreign Economic Activities led by Doctor of Economics, Professor I. Platonova has been investigating the problems of improving the architecture of foreign economic network and the international competitiveness of Russia; - The history of the study of problems of the world economy at MGIMO begins in 1958 at the chair baring the same name. Since 1998, the department has been headed by Professor A. Bulatov; - The study of international monetary relations is based on the chair of International Finance, and is focused on addressing the fundamental scientific and practical problems; - The chair "Banks, monetary circulation

  12. Rapid geophysical surveyor

    International Nuclear Information System (INIS)

    Roybal, L.G.; Carpenter, G.S.; Josten, N.E.

    1993-01-01

    The Rapid Geophysical Surveyor (RGS) is a system designed to rapidly and economically collect closely-spaced geophysical data used for characterization of Department of Energy (DOE) waste sites. Geophysical surveys of waste sites are an important first step in the remediation and closure of these sites; especially older sties where historical records are inaccurate and survey benchmarks have changed due to refinements in coordinate controls and datum changes. Closely-spaced data are required to adequately differentiate pits, trenches, and soil vault rows whose edges may be only a few feet from each other. A prototype vehicle designed to collect magnetic field data was built at the Idaho national Engineering Laboratory (INEL) during the summer of 1992. The RGS was one of several projects funded by the Buried Waste Integrated Demonstration (BWID) program. This vehicle was demonstrated at the Subsurface Disposal Area (SDA) within the Radioactive Waste Management Complex (RWMC) on the INEL in September of 1992. Magnetic data were collected over two areas in the SDA, with a total survey area of about 1.7 acres. Data were collected at a nominal density of 2 1/2 inches along survey lines spaced 1 foot apart. Over 350,000 data points were collected over a 6 day period corresponding to about 185 man-days using conventional ground survey techniques. This report documents the design and demonstration of the RGS concept including the presentation of magnetic data collected at the SDA. The surveys were able to show pit and trench boundaries and determine details of their spatial orientation never before achieved

  13. Environmentally Sustainable Economic Growth

    Directory of Open Access Journals (Sweden)

    Stelian Brad

    2016-05-01

    Full Text Available Economic growth and sustainable development are important issues for social prosperity. Sustainable development strives for moderate and responsible use within the economic activity of the limited resources of our planet, whereas economic growth does not limit the resource exploitation and energy, being mainly focused on productivity increase. From this perspective, both conceptual and operational contradictions occur between the two pillars of prosperity. This paper looks to these contradictions and proposes some streams of intervention such as economic growth and environmental sustainability to operate in harmony. A structured framework for innovative problem solving is considered in this respect. Results of this research show that it is possible to induce smart measures in the economic system for directing businesses towards new paradigms where economic growth is possible without negative effects on environmental sustainability.

  14. Uruguay; Recent Economic Developments

    OpenAIRE

    International Monetary Fund

    1996-01-01

    This paper describes economic developments in Uruguay during the 1990s. Real GDP expanded on average by more than 4 percent a year in 1990–94 and fell by 2½ percent in 1995. The rapid growth of output during 1990–94 reflected buoyant external demand from Uruguay’s main trading partners (Argentina and Brazil), as well as progress in strengthening the public finances, reducing wage indexation, opening the economy, and curtailing government intervention. Consumer price inflation fell steadily fr...

  15. Rapidly variable relatvistic absorption

    Science.gov (United States)

    Parker, M.; Pinto, C.; Fabian, A.; Lohfink, A.; Buisson, D.; Alston, W.; Jiang, J.

    2017-10-01

    I will present results from the 1.5Ms XMM-Newton observing campaign on the most X-ray variable AGN, IRAS 13224-3809. We find a series of nine absorption lines with a velocity of 0.24c from an ultra-fast outflow. For the first time, we are able to see extremely rapid variability of the UFO features, and can link this to the X-ray variability from the inner accretion disk. We find a clear flux dependence of the outflow features, suggesting that the wind is ionized by increasing X-ray emission.

  16. Economic Darwinism

    DEFF Research Database (Denmark)

    Sloth, Birgitte; Whitta-Jacobsen, Hans Jørgen

    2011-01-01

    We define an evolutionary process of "economic Darwinism" for playing the field, symmetric games. The process captures two forces. One is "economic selection": if current behavior leads to payoff differences, behavior yielding lowest payoff has strictly positive probability of being replaced...... in the literature. Using this result, we demonstrate that generally under positive (negative) externalities, economic Darwinism implies even more under- (over-)activity than does Nash equilibrium....

  17. Economic Darwinism

    DEFF Research Database (Denmark)

    Sloth, Birgitte; Whitta-Jacobsen, Hans Jørgen

    We define an evolutionary process of “economic Darwinism” for playing-the-field, symmetric games. The process captures two forces. One is “economic selection”: if current behavior leads to payoff differences, behavior yielding lowest payoff has strictly positive probability of being replaced...... in the literature. Using this result, we demonstrate that generally under positive (negative) externalities, economic Darwinism implies even more under- (over-) activity than does Nash equilibrium...

  18. Qualitative Economics

    DEFF Research Database (Denmark)

    Fast, Michael; Clark, Woodrow

    2012-01-01

    the everyday economic life is the central issue and is discussed from the perspective of interactionism. It is a perspective developed from the Lifeworld philosophical traditions, such as symbolic interactionism and phenomenology, seeking to develop the thinking of economics. The argument is that economics...... and the process of thinking, e.g. the ontology and the epistemology. Keywords: qualitative, interaction, process, organizing, thinking, perspective, epistemology....

  19. ECOLOGICAL ECONOMICS VS ECONOMIC(AL ECOLOGY

    Directory of Open Access Journals (Sweden)

    G. Kharlamova

    2015-10-01

    Full Text Available Currently world faces the dilemma – ecological economy or economic(al ecology. The researchers produce hundreds of surveys on the topic. However the analyses of recent most cited simulations had shown the diversity of results. Thus, for some states the Kuznets environmental curve has place, for others – no. Same could be said about different years for the same state. It provokes the necessity of drawing new group analyses to reveal the tendencies and relationships between economic and environmental factors. Most flexible and mirror factor of environmental sustainability is the volume of CO2 emissions. The econometric analysis was used for detecting the economic impact on this indicator at the global level and in the spectra of group of states depending on their income. The hypothesis of the existence of environmental Kuznets curve for the analysed data is rejected. Real GDP per capita impact on carbon dioxide emissions is considered only at the global level. The impact of openness of the economy is weak. Rejection happened also to the hypothesis that for the developed countries there is a reverse dependence between the environmental pollution and economic openness. Indicator “energy consumption per capita” impacts on greenhouse gas emissions only in countries with high income. Whereby it should be noted that the more developed a country is, the more elastic is this influence. These results have a potential usage for environmental policy regulation and climate strategy.

  20. Qualitative Economics

    DEFF Research Database (Denmark)

    Fast, Michael; Clark II, Woodrow W

                         This book is about science -- specifically, the science of economics. Or lack thereof is more accurate. The building of any science, let alone economics, is grounded in the understanding of what is beneath the "surface" of economics. Science, and hence economics, should...... be concerned with formulating ideas that express theories which produce descriptions of how to understand phenomenon and real world experiences.                       Economics must become a science, because the essence of economics in terms of human actions, group interactions and communities are in need...... of scientific inquiry. Academics and scholars need a scientific perspective that can hypothesize, theorize document, understand and analyze human dynamics from the individual to more societal interactions. And that is what qualitative economics does; it can make economics into becoming a science. The economic...

  1. Economic development and family size.

    Science.gov (United States)

    Rios, R J

    1991-01-01

    The demographic transition in Latin America has resulted in increased family size rather than the Western European model of reduced family size. In 1905, both fertility and mortality were high in Latin America, but mortality declined more rapidly in Latin America than in Europe. In 1905, the crude birth rate for 15 selected countries averaged 44/1000 population. Western fertility at a comparable transition point was much lower at 30/1000. Between 1905 and 1960, fertility declines were evident in Uruguay, Argentina, Cuba, and Chile. Between 1960 and 1985, fertility declines appeared in Costa Rica, Panama, Brazil, and Colombia. Fertility declines were smaller in the other Latin American countries. Crude birth rates declined markedly by 1985 but may overestimate fertility decline, which is more accurately measured by standardized birth rates. Fertility decline was evident in Argentina, Chile, and Costa Rica for standardized birth rates, survivorship ratio, and births surviving past the age of 15 years. Theoretically, families are expected to reduce family size when survivorship is assured; when mortality is 25%, only four children need be planned instead of six when mortality is 50%. A result of falling mortality is a cheaper cost of producing children, which may stimulate parents to raise bigger families. Western fertility decline has been attributed to mortality decline, urbanization, increased female labor force participation, rising wages, and more efficient contraception. Comparable economic development in Latin America has not resulted in large enough changes to encourage family size limitation. A table of fertility and economic indicators for selected countries in Latin America and Europe reflects the inverse relationship between income growth, urban growth, and growth in female educational status and fertility. The regression equation explains 60% of the variation in fertility rates among Latin American countries. Explanatory power increases to 75% when female

  2. Economic impacts study

    Energy Technology Data Exchange (ETDEWEB)

    Brunsen, W.; Worley, W.; Frost, E.

    1988-09-30

    This is a progress report on the first phase of a project to measure the economic impacts of a rapidly changing U.S. target base. The purpose of the first phase is to designate and test the macroeconomic impact analysis model. Criteria were established for a decision-support model. Additional criteria were defined for an interactive macroeconomic impact analysis model. After a review of several models, the Economic Impact Forecast System model of the U.S. Army Construction Research Laboratory was selected as the appropriate input-output tool that can address local and regional economic analysis. The model was applied to five test cases to demonstrate its utility and define possible revisions to meet project criteria. A plan for EIFS access was defined at three levels. Objectives and tasks for scenario refinement are proposed.

  3. Impact of Flexibility Options on Grid Economic Carrying Capacity of Solar and Wind: Three Case Studies

    Energy Technology Data Exchange (ETDEWEB)

    Denholm, Paul [National Renewable Energy Lab. (NREL), Golden, CO (United States); Novacheck, Joshua [National Renewable Energy Lab. (NREL), Golden, CO (United States); Jorgenson, Jennie [National Renewable Energy Lab. (NREL), Golden, CO (United States); O' Connell, Matthew [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-12-01

    In this study, we attempt to quantify the benefits of various options of grid flexibility by measuring their impact on two measures: economic carrying capacity and system costs. Flexibility can increase economic carrying capacity and reduce overall system costs. In some cases, options that provide a limited increase in economic carrying capacity can provide significant operational savings, thus demonstrating the need to evaluate flexibility options using multiple metrics. The value of flexibility options varies regionally due to different generation mixes and types of renewables. The more rapid decline in PV value compared to wind makes PV more dependent on adding flexibility options, including transmission and energy storage.

  4. The Economic and Social Consequences of Gambling on the Tourism Industry in Macau

    OpenAIRE

    Wong, Weng U

    2007-01-01

    Macau is known as the Eastern Monte Carlo, her main industry of gambling makes Macau a rapid economic expansion and brings Macau a lot of job opportunities. However, in recent years, crime and negative social impacts have increased as a result of this industry. Gambling making Macau's economic structure lopsided and fragile as well as bring a series of social problems to Macau. This dissertation illustrates both the positive and negative impacts that Macau's gambling industry is having on int...

  5. Beyond demographics is destiny: understanding economic mitigation strategies for demographic change in China

    OpenAIRE

    Judy, John B.

    2015-01-01

    Approved for public release; distribution is unlimited The favorable demographics that have contributed to China’s rapid economic growth are changing. China’s working-age population is currently peaking and within two decades its overall population will begin to shrink. In addition to a shrinking working-age population, China will see an increase in the elderly population and a rising dependency ratio. This demographic change may have an economically significant impact. If China’s enormous...

  6. Socio-economic perspectives on shifting cultivation landscapes in Northern Laos

    DEFF Research Database (Denmark)

    Heinimann, Andreas; Hett, Cornelia; Hurni, Kaspar

    2013-01-01

    Despite the rapid agricultural transition that has occurred in the past decade, shifting cultivation remains a widespread agricultural practice in the northern uplands of Lao PDR. Little information is available on the basic socio-economic situation and respective possible patterns in shifting cu...... minorities, pointing to multi-dimensional marginality of these areas. We discuss whether economic growth and increased market accessibility are sufficient to lift these landscapes out of poverty....

  7. "New Economics"?

    DEFF Research Database (Denmark)

    Nielsen, Jørgen Ulff-Møller

    1999-01-01

    The United States, the United Kingdom and Denmark have all enjoyed a long period of high stable growth and low inflation in the 1990s. Attempts to determine the implications of this have led to the so-called "New Economics", whose advocates claim that the relationship between economic growth...

  8. A CONCEPTUAL APPROACH TO ECONOMIC AGGLOMERATIONS

    Directory of Open Access Journals (Sweden)

    Mădălina-Ștefania Dîrzu

    2012-09-01

    Full Text Available Technological progress and rapid structural adjustments have characterized a lot of economies in the last century and they still feature pronounced structures. An important observation is that economic activities tend to agglomerate in space as a result of some kind increasing returns, forming eventually economic agglomerations. When various companies gather together, they establish specific forms of interaction. Increasing returns produce when this mutual interplay creates positive externalities for those firms which operate into an agglomeration. In this context, it is crucial to raise a question: what is an economic agglomeration and what do different scientists imply when using the concept? The phenomenon of agglomeration has attracted researchers from various disciplines employing a hybrid set of analytical perspectives. This whole framework is still puzzled with contradictory conceptualizations which are often used in an ambiguous way. Scientists tend to utilize notions such as agglomeration, cluster, territorial network, specialization, concentration somewhat interchangeably and with little concern about how to operationalize them. To shed a light on this issue, the aim of this paper is to provide a comprehensive analyze of different theoretical framework in which economic agglomerations have been debated and researched.

  9. Improving early cycle economic evaluation of diagnostic technologies.

    Science.gov (United States)

    Steuten, Lotte M G; Ramsey, Scott D

    2014-08-01

    The rapidly increasing range and expense of new diagnostics, compels consideration of a different, more proactive approach to health economic evaluation of diagnostic technologies. Early cycle economic evaluation is a decision analytic approach to evaluate technologies in development so as to increase the return on investment as well as patient and societal impact. This paper describes examples of 'early cycle economic evaluations' as applied to diagnostic technologies and highlights challenges in its real-time application. It shows that especially in the field of diagnostics, with rapid technological developments and a changing regulatory climate, early cycle economic evaluation can have a guiding role to improve the efficiency of the diagnostics innovation process. In the next five years the attention will move beyond the methodological and analytic challenges of early cycle economic evaluation towards the challenge of effectively applying it to improve diagnostic research and development and patient value. Future work in this area should therefore be 'strong on principles and soft on metrics', that is, the metrics that resonate most clearly with the various decision makers in this field.

  10. Offshore hydrocarbon resources in the Arctic: from cooperation to confrontation in an era of geopolitical and economic turbulence?

    OpenAIRE

    Morgunova, Maria; Westphal, Kirsten

    2016-01-01

    The Arctic region has been an area of low tension since the end of the Cold War. This observation is important because the run on hydrocarbons in the Arctic has not resulted in increased rivalries as expected. The outcomes have been international joint ventures in oil and gas project on the economic side and a strengthening of Arctic governance in the political realm. Since 2014, the situation has changed rapidly. Economic interests in hydrocarbon development are increasingly diverging betwee...

  11. Estimating the economic consequences of an increased medication adherence due to a potential improvement in the inhaler technique with Spiromax® compared with Turbuhaler® in patients with moderate-to-severe chronic obstructive pulmonary disease in Spain

    Directory of Open Access Journals (Sweden)

    Darbà J

    2017-02-01

    Full Text Available Josep Darbà,1 Gabriela Ramírez,2 Juan L García-Rivero,3 Sagrario Mayoralas,4 José Francisco Pascual,5 Diego Vargas,6 Adi Bijedic7 1Department of Economics, Universitat de Barcelona, 2BCN Health Economics & Outcomes Research S.L., Barcelona, 3Hospital Laredo, Cantabria, 4Hospital Ramón y Cajal, Madrid, 5Hospital General Universitario de Alicante, Alicante, 6Hospital de Alta Resolución el Toyo, Andalusia, 7Market Access and HEOR Department, TEVA Pharmaceutical, Madrid, Spain Objective: The objective of this study was to estimate the economic impact of the introduction of DuoResp® Spiromax®, budesonide/formoterol fixed-dose combination (FDC, focusing on an increase in medication adherence due to an enhancement of the inhalation technique for the treatment of COPD patients in Spain and 5 regions including Andalusia, Catalonia, Galicia, Madrid, and Valencia.Methods: A 4-year budget impact model was developed for the time period of 2015–2018. This study aimed at evaluating the budget impact associated with the introduction of DuoResp Spiromax in comparison with Symbicort® Turbuhaler® and Rilast® Turbuhaler. National and regional data on COPD prevalence were obtained from the literature. Input data on health care resource utilization were obtained by clinical consultation. Resource included primary care visits, specialist visits, hospitalization, and emergency room visits as well as the length of hospital stay. Based on both pharmacological and health care resource costs, overall annual treatment cost per patient was estimated in EUR 2015. Results: It was calculated that 130,777 adults were treated with budesonide/formoterol FDC delivered by a dry powder inhaler, Turbuhaler, in Spain in 2015. However, the target population decreases over the next 4 years. This pattern was observed in 4 regions, but for Andalusia, the treated population increased slightly. The overall budget savings in Spain with the market share of DuoResp Spiromax were

  12. Evaluation of community-level interventions to increase early initiation of antenatal care in pregnancy: protocol for the Community REACH study, a cluster randomised controlled trial with integrated process and economic evaluations.

    Science.gov (United States)

    Sawtell, Mary; Sweeney, Lorna; Wiggins, Meg; Salisbury, Cathryn; Eldridge, Sandra; Greenberg, Lauren; Hunter, Rachael; Kaur, Inderjeet; McCourt, Christine; Hatherall, Bethan; Findlay, Gail; Morris, Joanne; Reading, Sandra; Renton, Adrian; Adekoya, Ruth; Green, Belinda; Harvey, Belinda; Latham, Sarah; Patel, Kanta; Vanlessen, Logan; Harden, Angela

    2018-03-05

    The provision of high-quality maternity services is a priority for reducing inequalities in health outcomes for mothers and infants. Best practice includes women having their initial antenatal appointment within the first trimester of pregnancy in order to provide screening and support for healthy lifestyles, well-being and self-care in pregnancy. Previous research has identified inequalities in access to antenatal care, yet there is little evidence on interventions to improve early initiation of antenatal care. The Community REACH trial will assess the effectiveness and cost-effectiveness of engaging communities in the co-production and delivery of an intervention that addresses this issue. The study design is a matched cluster randomised controlled trial with integrated process and economic evaluations. The unit of randomisation is electoral ward. The intervention will be delivered in 10 wards; 10 comparator wards will have normal practice. The primary outcome is the proportion of pregnant women attending their antenatal booking appointment by the 12th completed week of pregnancy. This and a number of secondary outcomes will be assessed for cohorts of women (n = approximately 1450 per arm) who give birth 2-7 and 8-13 months after intervention delivery completion in the included wards, using routinely collected maternity data. Eight hospitals commissioned to provide maternity services in six NHS trusts in north and east London and Essex have been recruited to the study. These trusts will provide anonymised routine data for randomisation and outcomes analysis. The process evaluation will examine intervention implementation, acceptability, reach and possible causal pathways. The economic evaluation will use a cost-consequences analysis and decision model to evaluate the intervention. Targeted community engagement in the research process was a priority. Community REACH aims to increase early initiation of antenatal care using an intervention that is co-produced and

  13. Rapid and sustained cost management

    International Nuclear Information System (INIS)

    Hanson, D.

    2009-01-01

    Accenture helps clients develop comprehensive, process-driven strategies for rapid and sustained cost management that leverage deep insights and analytics. This approach enables companies to gain operating cost advantages by rationalizing, simplifying and automating current operating capabilities. It drives structural cost advantages by optimizing business mix, capital structure, organizational structure and geographic presence. This paper discussed how successful companies achieve high performance during times of economic turmoil. It also discussed the value of the winner's strategy in terms of rapid and sustained cost management (RSCM). It discussed how Accenture operates and its leveraged capabilities, improved efficiency, margins and cash flow while maintaining customer service levels. Building structural advantage and the Accenture difference were also discussed. It was concluded that RSCM is one vital way that Accenture can help companies achieve success. 4 figs

  14. Space and economics : An introduction to regional economics

    NARCIS (Netherlands)

    Heijman, W.J.M.; Schipper, R.A.

    2010-01-01

    The subject area Regional Economics is becoming more and more topical. This means that in economic analyses the production factor 'space' is of increasing importance. This study book aims to integrate space in the area of General Economics in an analytical way. Models and their applications play a

  15. Development economics

    International Nuclear Information System (INIS)

    Roebuck, F.

    1992-01-01

    This paper discusses term development economics which refers to the economic evaluation of investment opportunities that occur after the discovery well is drilled and completed. with specific regard to the techniques used and the economic yardsticks available for investment decisions. Three potential situations are considered in this paper: the incorporation of development wells into the outcomes of the original exploration project, mutually exclusive or alternative investment opportunities, and the installation of improved or enhanced recovery projects during or at the end of the primary producing life of a property

  16. Can cognitive dissonance methods developed in the West for combatting the ‘thin ideal’ help slow the rapidly increasing prevalence of eating disorders in non-Western cultures?

    Science.gov (United States)

    Witcomb, Gemma L.; Arcelus, Jon; Chen, Jue

    2013-01-01

    Summary Eating disorders are common, life-threatening conditions in Western countries, but until relatively recently they were regarded as uncommon in non-Western cultures. However, the prevalence of eating disorders in many of the more affluent non-Western countries is rising rapidly as community members, particularly young women, internalize the ‘thin ideal’ that has been widely promoted by the international media. This review discusses the factors involved in the development of eating disorders in non-Western settings with a particular emphasis on the influences of urbanization, modernization, Westernization, and the resulting changes in women's roles. The cognitive dissonance programs developed in Western countries that have proven successful in countering the negative effects of the thin idea are described and their potential application to East Asia and other non-Western countries are discussed. PMID:24991176

  17. What are the socio-economic impacts of genetically modified crops worldwide? A systematic map protocol

    NARCIS (Netherlands)

    Garcia-Yi, J.; Lapikanonth, T.; Vionita, H.; Vu, H.; Yang, S.; Zhong, Y.; Li, Y.; Nagelschneider, V.; Schlindwein, B.; Wesseler, J.H.H.

    2014-01-01

    Genetically modified (GM) crops have generated a great deal of controversy. Since commercially introduced to farmers in 1996, the global area cultivated with GM crops has increased 94-fold. The rapid adoption of GM technology has had substantial socio-economic impacts which a vast amount of

  18. Environmental Economics

    International Development Research Centre (IDRC) Digital Library (Canada)

    David Glover, Bhim Adhikari and Isabelle Proulx

    Economy and Environment Program for Southeast Asia. ERF. Economic ... economists can contribute to this work by estimating the monetary value of such environment-related benefits ... One of the few safe places to put money has been land, ...

  19. "New Economics"?

    DEFF Research Database (Denmark)

    Nielsen, Jørgen Ulff-Møller

    1999-01-01

    The United States, the United Kingdom and Denmark have all enjoyed a long period of high stable growth and low inflation in the 1990s. Attempts to determine the implications of this have led to the so-called "New Economics", whose advocates claim that the relationship between economic growth and ...... and inflation has fundamentally changes. The following article tests this thesis against current data for the USA.......The United States, the United Kingdom and Denmark have all enjoyed a long period of high stable growth and low inflation in the 1990s. Attempts to determine the implications of this have led to the so-called "New Economics", whose advocates claim that the relationship between economic growth...

  20. Exploration economics

    International Nuclear Information System (INIS)

    Mcgill, R.E.

    1992-01-01

    This paper deals with determining the economic viability of the play or prospect. At the outset, one point is important. Preexploration economists are important because they enable geologists to see if their assumptions will prove profitable. Their assumptions must consider the full range of possible outcomes, even if only some portion of that range may contain prospects or plays that are estimated to be profitable. Play economics are preferable to prospect economics because, being the sum of several prospects, they give a broader view of the investment opportunity. Finally, remember that play and prospect economics are always slightly optimistic. They seldom include all of the exploration and overhead changes that must ultimately be borne by the successful prospects

  1. BEHAVIORAL ECONOMICS AND THE NEED OF PSYCHOLOGY IN ECONOMIC RESEARCH

    Directory of Open Access Journals (Sweden)

    Andreea GRADINARU

    2014-06-01

    Full Text Available The turning point in economic science has now come, marked especially by triggering the biggest crisis since the Great Depression of '29-'33, has called into question the need to reconsider the status of economic science and finding ways in which it can increase its practical foundations. In the elaboration of this study I’ve took into account the fact that beyond any abstract, formal and mathematical model, economics is a science, having the man in its center. Furthermore, every economic process is based on the human being. But the way individuals behave does not follow precisely the pattern predicted by classical and neoclassical models, but most of the time they are making decisions under the influence of psychological factors. Starting from these assumptions I considered important to highlight a real need for psychology in economic research. Therefore, the aim of this work is exclusively theoretical meant to show that the study of psychological factors is necessary in economic research, because it allows a better explanation of the economic problems and lead to obtaining results closer to reality than those who only take into consideration economic factors. In this way I appealed to behavioral economics. This represents a new trend of economic thinking that reunites psychology with economy. The thing that I observed after finishing the study is that behavioral economics can increase the explanatory power of economics by providing more realistic psychological bases, because human behavior is not only the subject matter of economics but psychology too.

  2. Behavioral Economics

    OpenAIRE

    Sendhil Mullainathan; Richard H. Thaler

    2000-01-01

    Behavioral Economics is the combination of psychology and economics that investigates what happens in markets in which some of the agents display human limitations and complications. We begin with a preliminary question about relevance. Does some combination of market forces, learning and evolution render these human qualities irrelevant? No. Because of limits of arbitrage less than perfect agents survive and influence market outcomes. We then discuss three important ways in which humans devi...

  3. Building economics

    DEFF Research Database (Denmark)

    Pedersen, D.O.(red.)

    Publikationen er på engelsk. Den omfatter alle indlæg på det fjerde internationale symposium om byggeøkonomi, der blev arrangeret af SBI for det internationale byggeforskningsråd CIB. De fem bind omhandler: Methods of Economic Evaluation, Design Optimization, Ressource Utilization, The Building...... Market og Economics and Technological Forecasting in Construction. Et indledende bind bringer statusrapporter for de fem forskningsområder, og det sidste bind sammenfatter debatten på symposiet....

  4. Behavioral economics

    OpenAIRE

    Camerer, Colin F.

    2014-01-01

    Economics, like behavioral psychology, is a science of behavior, albeit highly organized human behavior. The value of economic concepts for behavioral psychology rests on (1) their empirical validity when tested in the laboratory with individual subjects and (2) their uniqueness when compared to established behavioral concepts. Several fundamental concepts are introduced and illustrated by reference to experimental data: open and closed economies, elastic and inelastic demand, and substitutio...

  5. The Chinese experience of rapid modernization: sociocultural changes, psychological consequences?

    Directory of Open Access Journals (Sweden)

    Jiahong eSun

    2016-04-01

    Full Text Available Mainland China has undergone profound changes dating back to the nineteenth century, including a contemporary period of rapid modernization that began in the 1980s. The result has been dramatic social, cultural, and economic shifts impacting the daily lives of Chinese people. In this paper, we explore the psychological implications of sociocultural transformation in China, emphasizing two central themes. First, rising individualism: findings from social and developmental psychology suggest that China’s rapid development has been accompanied by ever-increasing adherence to individualistic values. Second, rising rates of depression: findings from psychiatric epidemiology point to increasing prevalence of depression over this same time period, particularly in rural settings. We argue that links between sociocultural and psychological shifts in China can be usefully studied through a cultural psychology lens, emphasizing the mutual constitution of culture, mind, and brain. In particular, we note that the link between social change, individualism, and rising mental illness deserves careful attention. Our review suggests that shifting values and socialization practices shape emotion norms of concealment and display, with implications for depressive symptom presentation. The challenge comes with interpretation. Increasing prevalence rates of depression may indeed be a general response to the rapidity of sociocultural change, or a specific consequence of rising individualism—but may also result from increasingly ‘Western’ patterns of symptom presentation, or improvements in diagnostic practice. We conclude by considering the challenges posed to standard universal models of psychological phenomena.

  6. The Chinese Experience of Rapid Modernization: Sociocultural Changes, Psychological Consequences?

    Science.gov (United States)

    Sun, Jiahong; Ryder, Andrew G.

    2016-01-01

    Mainland China has undergone profound changes dating back to the nineteenth century, including a contemporary period of rapid modernization that began in the 1980s. The result has been dramatic social, cultural, and economic shifts impacting the daily lives of Chinese people. In this paper, we explore the psychological implications of sociocultural transformation in China, emphasizing two central themes. First, rising individualism: findings from social and developmental psychology suggest that China’s rapid development has been accompanied by ever-increasing adherence to individualistic values. Second, rising rates of depression: findings from psychiatric epidemiology point to increasing prevalence of depression over this same time period, particularly in rural settings. We argue that links between sociocultural and psychological shifts in China can be usefully studied through a cultural psychology lens, emphasizing the mutual constitution of culture, mind, and brain. In particular, we note that the link between social change, individualism, and rising mental illness deserves careful attention. Our review suggests that shifting values and socialization practices shape emotion norms of concealment and display, with implications for depressive symptom presentation. The challenge comes with interpretation. Increasing prevalence rates of depression may indeed be a general response to the rapidity of sociocultural change, or a specific consequence of rising individualism—but may also result from increasingly ‘Western’ patterns of symptom presentation, or improvements in diagnostic practice. We conclude by considering the challenges posed to standard universal models of psychological phenomena. PMID:27092093

  7. PUBLIC EDUCATION AND ECONOMIC COMPETITIVENESS

    Directory of Open Access Journals (Sweden)

    Gabriel-Andrei Donici

    2011-09-01

    Full Text Available There is a certain connection between education and economic competitiveness. The relation between these two concepts is easy to intuit. On the medium and long term investments in education generate astrong increase in a country’s level of economic competitiveness. Through education the human capital is formed, and it affects all economic fields. Therefore we can observe that human capital has a decisive influence on the economic competitiveness of a country.

  8. Financial history and financial economics

    OpenAIRE

    Turner, John D.

    2014-01-01

    This essay looks at the bidirectional relationship between financial history and financial economics. It begins by giving a brief history of financial economics by outlining the main topics of interest to financial economists. It then documents and explains the increasing influence of financial economics upon financial history, and warns of the dangers of applying financial economics unthinkingly to the study of financial history. The essay proceeds to highlight the many insights that financi...

  9. JINR rapid communications

    International Nuclear Information System (INIS)

    1999-01-01

    The present collection of rapid communications from JINR, DUBNA, contains eight separate records on symmetry in modern physics (dedicated to the 100th anniversary of the birth of academician V.A.Fock), the double φ-meson production investigation on the Serpukhov accelerator, two-leptonic η-meson decays and SUSY without R parity, charge form factors and alpha-cluster internal structure of 12 C, increasing of muon-track reconstruction efficiency in ME1/1 Dubna prototype for the CMS/LHC, study of photon-structure function F 2 γ in the reaction e + e - → e + e - + hadrons at LEP2, jets reconstruction possibility in pAu and AuAu interactions at STAR RHIC and high-vacuum nondispersable gas absorber

  10. JINR rapid communications

    International Nuclear Information System (INIS)

    1996-01-01

    The present collection of rapid communications from JINR, Dubna, contains seven separate reports on the identification of events with a secondary vertex in the experiment EXCHARM, the zero degree calorimeter for CERN WA-98 experiment, a new approach to increase the resource of installation elements for super-high energy physics, a method of the in-flight production of exotic systems in the charge-exchange reactions, the neutron activation analysis for monitoring northern terrestrial ecosystems, a search for 28 O and study of the neutron-rich nuclei near the neutron closure N=20, a search for new neutron-rich nuclei with a 70A MeV 48 Ca beam. 33 figs., 4 tabs

  11. Dilepton distributions at backward rapidities

    International Nuclear Information System (INIS)

    Betemps, M. A.; Ducati, M. B. Gay; Oliveira, E. G. de

    2006-01-01

    The dilepton production at backward rapidities in pAu and pp collisions at RHIC and LHC energies is investigated in the dipole approach. The results are shown through the nuclear modification ratio R pA considering transverse momentum and rapidity spectra. The dilepton modification ratio presents interesting behavior at the backward rapidities when compared with the already known forward ones, since it is related with the large x kinematical region that is being probed. The rapidity dependence of the nuclear modification ratio in the dilepton production is strongly dependent on the Bjorken x behavior of the nuclear structure function ratio R F 2 =F 2 A /F 2 p . The R pA transverse momentum dependence at backward rapidities is modified due to the large x nuclear effects: at RHIC energies, for instance, the ratio R pA is reduced as p T increases, presenting an opposite behavior when compared with the forward one. It implies that the dilepton production at backward rapidities should carry information of the nuclear effects at large Bjorken x, as well as that it is useful to investigate the p T dependence of the observables in this kinematical regime

  12. Coping with the Global Economic Crisis: A Challenge to Technical ...

    African Journals Online (AJOL)

    There is rapid transformation of the economics of the developed countries of the ... economic crisis affecting both the developing and underdeveloped countries of ... creating new demands for more adaptable, multi-skilled and creative labour.

  13. Voodoo Economics:Voodoo Economics

    OpenAIRE

    Briones Alonso, Elena

    2017-01-01

    This dissertation collects three essays that aim to contribute to the field of cultural economics. There is growing recognition among economists and policy makers that culture matters for economic development, but in many cases this trend has not resulted in a thorough understanding of the role of culture, or a proper integration of existing knowledge in policy. This is particularly true for the area of food security. The second chapter addresses this issue by reviewing existing cross-discipl...

  14. "Economics Imperialism", Education Policy and Educational Theory

    Science.gov (United States)

    Allais, Stephanie

    2012-01-01

    This paper examines how economics imperialism (the increasing colonization of other disciplines by neoclassical economics) has affected contemporary education policies. I suggest that an increasing preoccupation with education meeting the needs of the economy, together with the prevalence of economic concepts outside of economics, have contributed…

  15. An analysis of social consequences of rapid fertility decline in China.

    Science.gov (United States)

    Liu, Z; Liu, L

    1988-12-01

    Rapid fertility decline in China has brought about 2 direct effects: 1) the natural increase of the population has slowed down, and 2) the age structure has changed from the young to the adult type. These 2 effects have caused a series of economic and social consequences. Rapid fertility decline increases the gross national product per capita and accelerates the improvement of people's lives. Rapid fertility decline slows population growth and speeds up the accumulation of capital and the development of the economy. Since 1981, accumulation growth has exceeded consumption growth. Fertility decline alleviates the enrollment pressure on primary and secondary schools, raises the efficiency of education funds, and promotes the popularization of education. The family planning program strengthens the maternal and child health care and the medical care systems. As the result of economic development, the people's nutritional levels are improving. The physical quality of teenagers has improved steadily. The change in the age structure will alleviate the tension of rapid population growth and benefit population control in the next century. Fertility decline forces the traditional attitude toward childbearing from "more children, more happiness" to improved quality of children. The rapid fertility decline has caused a great deal of concern both inside and outside China about the aging of the population. The labor force, however, will continue to grow for the next 60 years. At present, China's population problems are still those of population growth.

  16. Increasing hospital admission rates and economic burden for colorectal cancer in Brazil, 1996-2008 Aumento de las tasas de ingresos hospitalarios por cáncer colorrectal y su carga económica en Brasil, 1996-2008

    Directory of Open Access Journals (Sweden)

    Ulysses dos Santos Torres

    2010-10-01

    Full Text Available OBJECTIVE: To determine the trends in hospital admission rates for colorectal cancer (CRC in the Brazilian Public Health System from 1996 to 2008 and to assess the economic costs. METHODS: Data from the Hospital Information Systems database of the Brazilian Unified Health System were used for analysis of all admissions with a primary diagnosis of CRC between 1996 and 2008. RESULTS: There were 297 108 CRC admissions over the study period, with an annual increase from 12 821 in 1996 to 35 040 in 2008. Age-standardized admission rates increased from 8.7 to 23.56 per 100 000 for a percentage increase of 171%. The average length of stay decreased from 11.6 days in 1996 to 7.5 days in 2008. The average hospital mortality declined from 10.4% to 8.5%. Overall costs in United States dollars (US$ of CRC hospitalizations rose from US$ 16.5 million in 1996 to US$ 33.5 million in 2008; the average cost of each admission, however, decreased from US$ 1 283 to US$ 954. CONCLUSIONS: Hospitalization rates for CRC in Brazil significantly increased during a 13-year period, incurring a considerable rise in the inflation-adjusted economic burden; national in-hospital mortality rates have remained relatively high.OBJETIVO: Determinar las tendencias de las tasas de ingresos hospitalarios por cáncer colorrectal (CCR en el sistema de salud pública brasileño de 1996 al 2008 y evaluar sus costos económicos. MÉTODOS: Se utilizó la información de la base de datos de los sistemas de información de los hospitales del Sistema Único de Salud brasileño con objeto de analizar todos los ingresos con diagnóstico primario de CCR entre 1996 y el 2008. RESULTADOS: Durante el período de estudio, se produjeron 297 108 ingresos por CCR, con un aumento anual de 12 821 en 1996 a 35 040 en el 2008. Las tasas de ingresos estandarizadas según la edad aumentaron de 8,7 a 23,56 por 100 000, con un aumento porcentual de 171%. La estancia hospitalaria media disminuyó de 11,6 días en

  17. [The population and economic problems of South Asia].

    Science.gov (United States)

    Gu, J

    1983-07-29

    South Asia, which includes Central South Asia, Southeast Asia, and Southwest Asia, had a comparatively higher population growth rate during the 30-year postwar period because of the overall backward economy and strong religious tradition. From the viewpoint of economics, the high population growth in South Asia has slowed down economic growth, increased the foreign trade imblance, and worsened poverty. Secondly, the rapid population growth has overburdened the area's educational system. The illiteracy rate has been going up continuously because of inadequate funds available for education. Thirdly, young labor is lacking in skills, training, and work experience, and related productivity has declined. Consequently, profits, the investment capability, and wages are also declining. The problems of the oversupply of labor, unemployment, and poverty have also become increasingly serious. In addition, the rapid population growth has intensified the pressure on the food supply and worsened the average nutrition of the general public. In recent years, countries in South Asia have been trying to deal with various problems caused by the rapid population growth. Measures have been taken to control the population growth, with a redistribution of the population to places outside cities, and export labor to oil-producing nations of the Middle East and Africa in order to solve the problem of the domestic labor surplus and earn more income for the foreign exchange. Countries in South Asia need more time and effort to achieve a balance between the population growth and economic development.

  18. [Dynamic changes of the relationships between economic growth and environmental pressure in Gansu Province: a structural decomposition analysis].

    Science.gov (United States)

    Zhang, Zi-Long; Chen, Xing-Peng; Yang, Jing; Xue, Bing; Li, Yong-Jin

    2010-02-01

    Based on the ideology of macro environmental economics, a function of environmental pressure represented by pollutant emission was built, and the relative importance of the driving factors in the dynamic changes of the relationships between economic growth and environmental pressure in Gansu Province in 1990 - 2005 was analyzed by using structural decomposition analysis (SDA) model combining with 'refined Laspeyres' method. In the study period, the environmental pressure in the Province was mainly caused by the emission of waste gases and solids in the process of economic growth, and showed a rapid increasing trend at the late stage of the period. Population factor had less impact on the increase of this environmental pressure, while economic growth factor had obvious impact on it. Technological progress did mitigate, but could not offset the impact of economic growth factor, and the impacts of economic growth and technological factors on the environmental pressure differed with the kinds of pollutants.

  19. Economic fables

    OpenAIRE

    Moran, Shane

    2010-01-01

    I had the good fortune to grow up in a wonderful area of Jerusalem, surrounded by a diverse range of people: Rabbi Meizel, the communist Sala Marcel, my widowed Aunt Hannah, and the intellectual Yaacovson. As far as I'm concerned, the opinion of such people is just as authoritative for making social and economic decisions as the opinion of an expert using a model. Part memoir, part crash-course in economic theory, this deeply engaging book by one of the world's foremost economists looks at ...

  20. The dynamics of oil consumption and economic growth in Malaysia

    International Nuclear Information System (INIS)

    Park, Sun-Young; Yoo, Seung-Hoon

    2014-01-01

    This study attemps to investiagte the causal relationship between oil consumption and economic growth in Malaysia where oil consumption and real gross domestic product have been rapidly increased in recent years. To this end, the study employs annual data covering the period 1965–2011. Tests for unit roots, co-integration, and Granger-causality based on the error-correction models are presented. The overall results support the existence of bi-directional causality between oil consumption and economic growth in Malaysia. This means that an increase in oil consumption directly affect economic growth. Thus, in order not to make an adverse effect on economic growth, Malaysia should endeavor to overcome the constraints on oil consumption. Moreover, it appears that economic growth induces oil consumption. - Highlights: • We examine the causality between oil consumption and economic growth in Malaysia. • We employed the annual data covering the period 1965–2011. • We estimated error-correction models to test for the direction of causality. • We found that there is bi-directional causality between the two

  1. Building America's Job Skills with Effective Workforce Programs: A Training Strategy to Raise Wages and Increase Work Opportunities. Strategy Paper

    Science.gov (United States)

    Greenstone, Michael; Looney, Adam

    2011-01-01

    This paper discusses the importance of effective training and workforce development programs as part of a broader strategy to increase the competitiveness of American workers. Although rapid technological change and increasing global competition have delivered great economic benefits to the U.S. economy overall, the development of new and more…

  2. The Philippine economic mystery

    OpenAIRE

    Robert H. Nelson

    2007-01-01

    The poor economic performance of the Philippines over the long term is a puzzle and an apparent anomaly for the region. The decline in the Philippines' global position from the first part of the 20th century is particularly striking when viewed against the backrdrop of rapid income gains in countries of East and Southeast Asia, countries the Philippines used to surpass in terms of physical and human capital. While there have been a number of attempts to explain the puzzle—difficult geography,...

  3. [Economic aspects of epilepsy].

    Science.gov (United States)

    Argumosa, A; Herranz, J L

    2000-06-01

    The economic magnitude of epilepsy is determined by its effect on the employment status of the patients, the cost of drug treatment for them and the healthcare system and the repercussion worldwide. Studies of the cost of the disease show that it has economic importance due to the sum of the direct and indirect costs caused by it. In the case of epilepsy, the results of studies in various countries led to the creation of a Commission on Economic Aspects of Epilepsy. The lack of epidemiological studies regarding epilepsy in Spain may explain the lack of publications on this subject in our country. The percentage of the total cost due to antiepileptic drugs is considerable and will probably increase in the future. The pharmaco-economic evaluation made by cost-benefit, cost-effectiveness, cost-usefulness analysis and studies to minimize costs should serve to use healthcare resources in the most effective manner and justify the rational use of the new antiepileptic drugs. The economic impact of epilepsy is added to the repercussion of the disease itself on the patient and his family. The different distribution of costs in children and adults with epilepsy suggest the need for intervention at an early age to try to reduce the long term economic and personal repercussions. The pharmaco-economic evaluation of the new antiepileptic drugs will make it clear whether their considerable cost is worth paying for their greater effectivity.

  4. Economics of ALMR deployment

    International Nuclear Information System (INIS)

    Delene, J.G.; Fuller, L.C.; Hudson, C.R.

    1994-01-01

    The Advanced Liquid Metal Reactor (ALMR) has the potential to extend the economic life of the nuclear option and of reducing the number of high level waste repositories which will eventually be needed in an expanding nuclear economy. This paper reports on an analysis which models and evaluates the economics of the use of ALMRs as a component of this country's future electricity generation mix. The ALMR concept has the ability to utilize as fuel the fissile material contained in previously irradiated nuclear fuel (i.e., spent fuel) or from surplus weapons grade material. While not a requirement for the successful deployment of ALMR power plant technology, the reprocessing of spent fuel from light water reactors (LWR) is necessary for any rapid introduction of ALMR power plants. In addition, the reprocessing of LWR spent fuel may reduce the number of high level waste repositories needed in the future by burning the long-lived actinides produced in the fission process. With this study, the relative economics of a number of potential scenarios related to these issues are evaluated. While not encompassing the full range of all possibilities, the cases reported here provide an indication of the potential costs, timings, and relative economic attractiveness of ALMR deployment

  5. Single wafer rapid thermal multiprocessing

    International Nuclear Information System (INIS)

    Saraswat, K.C.; Moslehi, M.M.; Grossman, D.D.; Wood, S.; Wright, P.; Booth, L.

    1989-01-01

    Future success in microelectronics will demand rapid innovation, rapid product introduction and ability to react to a change in technological and business climate quickly. These technological advances in integrated electronics will require development of flexible manufacturing technology for VLSI systems. However, the current approach of establishing factories for mass manufacturing of chips at a cost of more than 200 million dollars is detrimental to flexible manufacturing. The authors propose concepts of a micro factory which may be characterized by more economical small scale production, higher flexibility to accommodate many products on several processes, and faster turnaround and learning. In-situ multiprocessing equipment where several process steps can be done in sequence may be a key ingredient in this approach. For this environment to be flexible, the equipment must have ability to change processing environment, requiring extensive in-situ measurements and real time control. This paper describes the development of a novel single wafer rapid thermal multiprocessing (RTM) reactor for next generation flexible VLSI manufacturing. This reactor will combine lamp heating, remote microwave plasma and photo processing in a single cold-wall chamber, with applications for multilayer in-situ growth and deposition of dielectrics, semiconductors and metals

  6. Importance of Economic Evaluation in Health Care: An Indian Perspective.

    Science.gov (United States)

    Dang, Amit; Likhar, Nishkarsh; Alok, Utkarsh

    2016-05-01

    Health economic studies provide information to decision makers for efficient use of available resources for maximizing health benefits. Economic evaluation is one part of health economics, and it is a tool for comparing costs and consequences of different interventions. Health technology assessment is a technique for economic evaluation that is well adapted by developed countries. The traditional classification of economic evaluation includes cost-minimization, cost-effectiveness analysis, cost-utility analysis, and cost-benefit analysis. There has been uncertainty in the conduct of such economic evaluations in India, due to some hesitancy with respect to the adoption of their guidelines. The biggest challenge in this evolutionary method is lack of understanding of methods in current use by all those involved in the provision and purchasing of health care. In some countries, different methods of economic evaluation have been adopted for decision making, most commonly to address the question of public subsidies for the purchase of medicines. There is limited evidence on the impact of health insurance on the health and economic well-being of beneficiaries in developing countries. India is currently pursuing several strategies to improve health services for its population, including investing in government-provided services as well as purchasing services from public and private providers through various schemes. Prospects for future growth and development in this field are required in India because rapid health care inflation, increasing rates of chronic conditions, aging population, and increasing technology diffusion will require greater economic efficiency into health care systems. Copyright © 2016 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  7. In Search of the Perfect Business Model: As personalized medicine moves into the mainstream, makers of diagnostics must face a new economic reality. How to develop a value proposition in a healthcare market that is becoming increasingly elastic?

    Science.gov (United States)

    Carlson, Bob

    2012-01-01

    As personalized medicine edges toward the mainstream, economic realities threaten its existence. But without companion diagnostics, "getting the right drug to the right person" could wind up being just a slogan. What's the right business model?

  8. Rapid Quantification of the Toxic Alga Prymnesium parvum in Natural Samples by Use of a Specific Monoclonal Antibody and Solid-Phase Cytometry

    DEFF Research Database (Denmark)

    West, N. J.; Bacchieri, R.; Hansen, Gert

    2006-01-01

    The increasing incidence of harmful algal blooms around the world and their associated health and economic effects require the development of methods to rapidly and accurately detect and enumerate the target species. Here we describe use of a solid-phase cytometer to detect and enumerate the toxi......-phase cytometer can be used to rapidly enumerate natural P. parvum cells and that it could be used to detect other toxic algae, with an appropriate antibody or DNA probe....

  9. Economic considerations

    International Nuclear Information System (INIS)

    Burns, W.A. Jr.

    1980-01-01

    A brief qualitative comparison of the technical differences between liquid membranes and three other technologies: biological treatment, ion exchange and solvent extraction is presented. It is shown how the differences can result in substantial economic advantages. For uranium recovery from phosphoric acid a lower organic loss is achieved by the liquid membrane than by the solvent extraction process. (U.K.)

  10. Food economics

    DEFF Research Database (Denmark)

    Hansen, Henning Otte

    and issues and such as food security, quality, obesity and health are ever important factors. This book describes the link between food markets and food companies from a theoretical and a business economics perspective. The relationships, trends and impacts on the international food market are presented...

  11. Mystical Economics

    Directory of Open Access Journals (Sweden)

    Marin Dinu

    2012-04-01

    Full Text Available The world envisioned by Economics resembles the Garden of Eden, where everything came from God, the pre-primordial sin people having nothing else to do but wait for the natural rhythms, set by the invisible hand, which is moved by the will and the power of the Creator.

  12. Economic impact

    Energy Technology Data Exchange (ETDEWEB)

    Technology Transfer Department

    2001-06-01

    In federal fiscal year 2000 (FY00), Berkeley Lab had 4,347 full- and part-time employees. In addition, at any given time of the year, there were more than 1,000 Laboratory guests. These guests, who also reside locally, have an important economic impact on the nine-county Bay Area. However, Berkeley Lab's total economic impact transcends the direct effects of payroll and purchasing. The direct dollars paid to the Lab's employees in the form of wages, salaries, and benefits, and payments made to contractors for goods and services, are respent by employees and contractors again and again in the local and greater economy. Further, while Berkeley Lab has a strong reputation for basic scientific research, many of the Lab's scientific discoveries and inventions have had direct application in industry, spawning new businesses and creating new opportunities for existing firms. This analysis updates the Economic Impact Analysis done in 1996, and its purpose is to describe the economic and geographic impact of Laboratory expenditures and to provide a qualitative understanding of how Berkeley Lab impacts and supports the local community. It is intended as a guide for state, local, and national policy makers as well as local community members. Unless otherwise noted, this analysis uses data from FY00, the most recent year for which full data are available.

  13. "Flooding Risk Analysis and the Understanding of Hydrological Disturbance due to the Rapid Urbanization in a Low-Scale Subwatershed in Houston Area". ( The project develops a relavant Model of flooding risk assessment to define the connection between increased streamflow/flooding and the rapid urban land development).

    Science.gov (United States)

    Geldiyev, P.

    2017-12-01

    Rapid urban development and changing climate influences the frequency and magnitude of flooding in Houston area. This proposed project aims to evaluate the flooding risks with the current and future land use changes by 2040 for one subbasin of the San Jacinto Brazos/Neches-Trinity Coastal basin. Surface environments and streamflow data of the Clear Creek are analyzed and stimulated to discuss the possible impact of urbanization on the occurrence of floods. The streamflow data is analyzed and simulated with the application of the Geographic Information Systems and its extensions. Both hydrologic and hydraulic models of the Clear Creek are created with the use of HEC-HMS and HEC-RAS software. Both models are duplicated for the year 2040, based on projected 2040 Landcover Maps developed by Houston and Galveston Area Council. This project examines a type of contemporary hydrologic disturbance and the interaction between land cover and changes in hydrological processes. Expected results will be very significant for urban development and flooding management.

  14. Rapid increase in resistance to third generation cephalosporins, imipenem and co-resistance in Klebsiella pneumoniae from isolated from 7,140 blood-cultures (2010-2014) using EARS-Net data in Spain.

    Science.gov (United States)

    Aracil-García, Belén; Oteo-Iglesias, Jesús; Cuevas-Lobato, Óscar; Lara-Fuella, Noelia; Pérez-Grajera, Isabel; Fernández-Romero, Sara; Pérez-Vázquez, María; Campos, José

    2017-10-01

    An analysis was made about the evolution of resistance to 3rd generation cephalosporins, imipenem, and other antibiotics in invasive isolates of Klebsiella pneumoniae (K. pneumoniae) according to the Spanish EARS-Net database (2010-2014). Forty-two hospitals from 16 Autonomous Communities with an approximate population coverage of 33% participated. A total 7,140 pneumoniae corresponding to the same number of patients were studied. Overall resistance percentages (I+R) were: cefotaxime 15.8%, ceftazidime 13.7%, imipenem 1.7%, ciprofloxacin 20.1%, tobramycin 14.1%, gentamicin 10.4%, and amikacin 1.9%. Resistance to 3rd generation cephalosporins increased from 9.8% (2010) to 19% (2014); to ciprofloxacin from 15.4% (2010) to 19.6% (2014); to gentamicin from 6.2% (2010) to 10.3% (2014) and to tobramycin from 7.1% (2010) to 14.2% (2014) (presistance to 3rd generation cephalosporins, ciprofloxacin, and aminoglycosides increased from 3.3% (2010) to 9.7% (2014) (pResistance to imipenem also increased from 0.27% (2010) to 3.46% (2014) (presistant to imipenem, of which 104 (86%) produced carbapenemases: 74 OXA-48, 14 VIM, 9 KPC (6 KPC-2 and 3 KPC-3), 6 IMP, and 1 GES. Over the 5 year period (2010-2014), resistance to 3rd generation cephalosporins in invasive K. pneumoniae in Spain has doubled. The combined resistance to 3rd generation cephalosporins, ciprofloxacin, and aminoglycosides has tripled, and imipenem resistance has increased almost 13 times, mostly due to the spread of carbapenemase-producing isolates. Copyright © 2016 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  15. Clusters and the new economics of competition.

    Science.gov (United States)

    Porter, M E

    1998-01-01

    Economic geography in an era of global competition poses a paradox. In theory, location should no longer be a source of competitive advantage. Open global markets, rapid transportation, and high-speed communications should allow any company to source any thing from any place at any time. But in practice, Michael Porter demonstrates, location remains central to competition. Today's economic map of the world is characterized by what Porter calls clusters: critical masses in one place of linked industries and institutions--from suppliers to universities to government agencies--that enjoy unusual competitive success in a particular field. The most famous example are found in Silicon Valley and Hollywood, but clusters dot the world's landscape. Porter explains how clusters affect competition in three broad ways: first, by increasing the productivity of companies based in the area; second, by driving the direction and pace of innovation; and third, by stimulating the formation of new businesses within the cluster. Geographic, cultural, and institutional proximity provides companies with special access, closer relationships, better information, powerful incentives, and other advantages that are difficult to tap from a distance. The more complex, knowledge-based, and dynamic the world economy becomes, the more this is true. Competitive advantage lies increasingly in local things--knowledge, relationships, and motivation--that distant rivals cannot replicate. Porter challenges the conventional wisdom about how companies should be configured, how institutions such as universities can contribute to competitive success, and how governments can promote economic development and prosperity.

  16. Rapid Prototyping Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The ARDEC Rapid Prototyping (RP) Laboratory was established in December 1992 to provide low cost RP capabilities to the ARDEC engineering community. The Stratasys,...

  17. Mental health, employment status and parenthood: the impact of the economic downturn on portuguese youth mental health

    OpenAIRE

    Frasquilho, Diana

    2017-01-01

    ABSTRACT: Background: Economic recessions pose significant risks to individuals’ mental health and well-being. Common mental disorders are already highly prevalent in Europe, and more so in Portugal. Thus, changes in macroeconomic conditions are likely to aggravate this scenario. The exponential and rapid increase of unemployment is a particular consequence of the economic recession that has been proven to have a detrimental effect on mental health and well-being at both individual and popula...

  18. Sector Economic Outlook. Energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-04-15

    The energy sector is a key driver of the economic pillar of Vision 2030. As the economy grows, urbanization intensifies and incomes increase, corporate and household demand for energy also rises. To meet this growth in demand for energy, the sector needs to increase investments and diversify into more sources of energy such as geothermal and wind power. It is therefore critical that focus is directed towards development and sustainability of the energy sector to ensure delivery of least cost power that will improve Kenya's competitiveness and achieve the Vision 2030 objective of 10% average annual economic growth.

  19. A review of economic impact of targeted oral anticancer medications.

    Science.gov (United States)

    Shen, Chan; Chien, Chun-Ru; Geynisman, Daniel M; Smieliauskas, Fabrice; Shih, Ya-Chen T

    2014-02-01

    There has been a rapid increase in the use of targeted oral anticancer medications (OAMs) in the past decade. As OAMs are often expensive, economic consideration play a significant role in the decision to prescribe, receive or cover them. This paper performs a systematic review of costs or budgetary impact of targeted OAMs to better understand their economic impact on the healthcare system, patients as well as payers. We present our review in a summary table that describes the method and main findings, take into account multiple factors, such as country, analytical approach, cost type, study perspective, timeframe, data sources, study population and care setting when we interpret the results from different papers, and discuss the policy and clinical implications. Our review raises a concern regarding the role of sponsorship on findings of economic analyses as the vast majority of pharmaceutical company-sponsored studies reported cost advantages toward the sponsor's drugs.

  20. Economic MPC based on LPV model for thermostatically controlled loads

    DEFF Research Database (Denmark)

    Zemtsov, Nikita; Hlava, Jaroslav; Frantsuzova, Galina

    2017-01-01

    Rapid increase of the renewable energy share in electricity production requires optimization and flexibility of the power consumption side. Thermostatically controlled loads (TCLs) have a large potential for regulation service provision. Economic model predictive control (MPC) is an advanced...... control method which can be used to syncronize the power consumption with undispatchable renewable electricity production. Thermal behavior of TCLs can be described by linear models based on energy balance of the system. In some cases, parameters of the model may be time-varying. In this work, we present...... a modified economic MPC based on linear parameter-varying model. In particular, we provide an exact transformation from a standard economic MPC formulation to a linear program. We assume that the variables influencing the model parameters are known (predictable) for the prediction horizon of the controller...

  1. Towards an economics of well-being

    NARCIS (Netherlands)

    McGregor, J.A.; Pouw, N.

    2017-01-01

    There is growing concern that presently dominant frameworks in economics no longer provide a way of adequately addressing and analysing the problems of today’s globalising and rapidly changing world. This article makes a number of fundamental proposals about how we might reframe economics to move it

  2. Promoting Women's Economic Participation in India

    OpenAIRE

    Ghani, Ejaz; Kerr, William R.; O'Connell, Stephen D.

    2013-01-01

    Despite rapid economic growth, gender disparities in women's economic participation have remained deep and persistent in India. What explains these gender disparities? Is it poor infrastructure, limited education, or the composition of the labor force and industries? Or is it deficiencies in social and business networks and a low share of incumbent female entrepreneurs? This note analyzes ...

  3. Economic analysis

    International Nuclear Information System (INIS)

    Owen, P.S.; Parker, M.B.; Omberg, R.P.

    1979-03-01

    The methodology used to arrive at the conclusions in the U.S. papers WG 5A-19 and WG 5A-22 with respect to the economics of fast breeders relative to LWR's is developed in detail in this contribution. In addition, sample calculations of the total levelized power cost of a standard LWR at $40/pound for U 3 O 8 and an FBR at a capital cost of 1.5 times that of an LWR are included. The respective total levalized power costs of the above two examples are 21.29 mills/kwh for the standard LWR and 28.48 mills/kwh for the FBR. It should be noted that the economic data used in these analyses are contained in the U.S. contribution, WG 5A-41

  4. Circulation economics

    DEFF Research Database (Denmark)

    Ingebrigtsen, Stig; Jakobsen, Ove

    2006-01-01

    Purpose - This paper is an attempt to advance the critical discussion regarding environmental and societal responsibility in economics and business. Design/methodology/approach - The paper presents and discusses as a holistic, organic perspective enabling innovative solutions to challenges...... concerning the responsible and efficient use of natural resources and the constructive interplay with culture. To reach the goal of sustainable development, the paper argues that it is necessary to make changes in several dimensions in mainstream economics. This change of perspective is called a turn towards...... sustainability. To illustrate the theoretical discussion, the paper gives some practical examples from the reprocessing industry in Norway. Findings - The paper finds, first, effective and efficient use of natural resources is necessary to implement circular value chains. Second, sustainable development...

  5. Rapid Tooling via Stereolithography

    OpenAIRE

    Montgomery, Eva

    2006-01-01

    Approximately three years ago, composite stereolithography (SL) resins were introduced to the marketplace, offering performance features beyond what traditional SL resins could offer. In particular, the high heat deflection temperatures and high stiffness of these highly filled resins have opened the door to several new rapid prototyping (RP) applications, including wind tunnel test modelling and, more recently, rapid tooling.

  6. Economic Modelling in Institutional Economic Theory

    Directory of Open Access Journals (Sweden)

    Wadim Strielkowski

    2017-06-01

    Full Text Available Our paper is centered around the formation of theory of institutional modelling that includes principles and ideas reflecting the laws of societal development within the framework of institutional economic theory. We scrutinize and discuss the scientific principles of this institutional modelling that are increasingly postulated by the classics of institutional theory and find their way into the basics of the institutional economics. We propose scientific ideas concerning the new innovative approaches to institutional modelling. These ideas have been devised and developed on the basis of the results of our own original design, as well as on the formalisation and measurements of economic institutions, their functioning and evolution. Moreover, we consider the applied aspects of the institutional theory of modelling and employ them in our research for formalizing our results and maximising the practical outcome of our paper. Our results and findings might be useful for the researchers and stakeholders searching for the systematic and comprehensive description of institutional level modelling, the principles involved in this process and the main provisions of the institutional theory of economic modelling.

  7. Rapid increase of Plasmodium falciparum dhfr/dhps resistant haplotypes, after the adoption of sulphadoxine-pyrimethamine as first line treatment in 2002, in southern Mozambique

    DEFF Research Database (Denmark)

    Enosse, Sonia; Magnussen, Pascal; Abacassamo, Fatima

    2008-01-01

    BACKGROUND: In late 2002, the health authorities of Mozambique implemented sulphadoxine-pyrimethamine (SP)/amodiaquine (AQ) as first-line treatment against uncomplicated falciparum malaria. In 2004, this has been altered to SP/artesunate in line with WHO recommendations of using Artemisinin...... Combination Therapies (ACTs), despite the fact that all the neighbouring countries have abandoned SP-drug combinations due to high levels of SP drug resistance. In the study area, one year prior to the change to SP/AQ, SP alone was used to treat uncomplicated malaria cases. The study described here...... haplotype (CIRNI) remained high and only changed marginally from 46% to 53% (P = 0.405) after one year with SP as first-line treatment in the study area. Conversely, the combined Pfdhfr/Pfdhps quintuple mutant haplotype increased from 8% to 26% (P = 0.005). The frequency of the chloroquine resistance...

  8. Integrated economics

    International Nuclear Information System (INIS)

    Bratton, T.J.

    1992-01-01

    This article offers ideas for evaluating integrated solid waste management systems through the use of a conceptual cost overview. The topics of the article include the integrated solid waste management system; making assumptions about community characteristics, waste generation rates, waste collection responsibility, integrated system components, sizing and economic life of system facilities, system implementation schedule, facility ownership, and system administration; integrated system costs; integrated system revenues; system financing; cost projections; and making decisions

  9. Economic analysis

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-06-01

    The Energy Policy and Conservation Act (EPCA) mandated that minimum energy efficiency standards be established for classes of refrigerators and refrigerator-freezers, freezers, clothes dryers, water heaters, room air conditioners, home heating equipment, kitchen ranges and ovens, central air conditioners, and furnaces. EPCA requires that standards be designed to achieve the maximum improvement in energy efficiency that is technologically feasible and economically justified. Following the introductory chapter, Chapter Two describes the methodology used in the economic analysis and its relationship to legislative criteria for consumer product efficiency assessment; details how the CPES Value Model systematically compared and evaluated the economic impacts of regulation on the consumer, manufacturer and Nation. Chapter Three briefly displays the results of the analysis and lists the proposed performance standards by product class. Chapter Four describes the reasons for developing a baseline forecast, characterizes the baseline scenario from which regulatory impacts were calculated and summarizes the primary models, data sources and assumptions used in the baseline formulations. Chapter Five summarizes the methodology used to calculate regulatory impacts; describes the impacts of energy performance standards relative to the baseline discussed in Chapter Four. Also discussed are regional standards and other program alternatives to performance standards. Chapter Six describes the procedure for balancing consumer, manufacturer, and national impacts to select standard levels. Details of models and data bases used in the analysis are included in Appendices A through K.

  10. Structural Change and Economic Development in China and India

    Directory of Open Access Journals (Sweden)

    Vittorio Valli

    2009-06-01

    Full Text Available The comparison of the periods of rapid economic growth in China since 1978 and India since 1992 markedly show different patterns of development and structural change. However, both countries experienced some advantages of "relative economic backwardness" and some aspects of the "fordist model of growth". China had an anticipated and deeper structural change, spurred mainly by economic reforms and the growth of the internal market in the 1980s, and, since the mid-1990s, by a very rapid penetration of its industrial products in the world market. However, a substantial part of China's exports in medium and high tech sectors are due to joint-ventures with foreign multinationals. India had a more balanced structural change and a slower insertion in the world market, although some sectors, such as software, steel, automotive and pharmaceuticals are recently increasing their share in the world markets. Owing to the huge number of micro-enterprises and the great size of the informal sector, India benefited much less than China from the economies of scale and from the third wave of the "fordist model of growth". Both countries, but in particular China, experienced negative externalities of this recent phase of rapid growth, such as higher inequalities, pollution and urban congestion.

  11. Energy, economics, environment and politics

    International Nuclear Information System (INIS)

    Foster, R.J.

    1993-01-01

    The pressure on the Earth's environment and resources is the ultimate result of population growth and the only humane means available for stabilizing world population is to increase per capita living standards in the developing countries. However, this will require a very large increase in global energy consumption. If, as at present, the energy demand is met largely by fossil fuels, atmospheric concentrations of CO 2 will rise rapidly. Until the end of the century, and perhaps beyond it, any actions to control CO 2 emissions will be taken for precautionary reasons alone, because no reliable basis will exist for predicting their global (or regional) impact on the climate. The sustainability of the natural environment is also under threat from human activities such as the clearing of forests for crop-growing and grazing. The resulting elimination of habitats for, and genetic variability in, the victor is as serious a concern as global warming. The economic and social consequences of rigidly curtailing the growth of energy use in developed countries would be severe, and in developing countries extreme; even then greenhouse gas build up could only be slowed not prevented. On the other hand, a wealthier world would be more able to bear the financial burden of protecting biodiversity. It is concluded that since the developed countries on whom the main cost would have to fall, adequate effort into both biodiversity and greenhouse gas reduction, biodiversity must take procedence. (1 figure, 2 tables). (UK)

  12. Rapid improvement teams.

    Science.gov (United States)

    Alemi, F; Moore, S; Headrick, L; Neuhauser, D; Hekelman, F; Kizys, N

    1998-03-01

    Suggestions, most of which are supported by empirical studies, are provided on how total quality management (TQM) teams can be used to bring about faster organizationwide improvements. Ideas are offered on how to identify the right problem, have rapid meetings, plan rapidly, collect data rapidly, and make rapid whole-system changes. Suggestions for identifying the right problem include (1) postpone benchmarking when problems are obvious, (2) define the problem in terms of customer experience so as not to blame employees nor embed a solution in the problem statement, (3) communicate with the rest of the organization from the start, (4) state the problem from different perspectives, and (5) break large problems into smaller units. Suggestions for having rapid meetings include (1) choose a nonparticipating facilitator to expedite meetings, (2) meet with each team member before the team meeting, (3) postpone evaluation of ideas, and (4) rethink conclusions of a meeting before acting on them. Suggestions for rapid planning include reducing time spent on flowcharting by focusing on the future, not the present. Suggestions for rapid data collection include (1) sample patients for surveys, (2) rely on numerical estimates by process owners, and (3) plan for rapid data collection. Suggestions for rapid organizationwide implementation include (1) change membership on cross-functional teams, (2) get outside perspectives, (3) use unfolding storyboards, and (4) go beyond self-interest to motivate lasting change in the organization. Additional empirical investigations of time saved as a consequence of the strategies provided are needed. If organizations solve their problems rapidly, fewer unresolved problems may remain.

  13. Portable Diagnostics and Rapid Germination

    Energy Technology Data Exchange (ETDEWEB)

    Dunn, Zachary Spencer [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-12-01

    In the Bioenergy and Defense Department of Sandia National Laboratories, characterization of the BaDx (Bacillus anthracis diagnostic cartridge) was performed and rapid germination chemistry was investigated. BaDx was tested with complex sample matrixes inoculated with Bacillus anthracis, and the trials proved that BaDx will detect Bacillus anthracis in a variety of the medium, such as dirt, serum, blood, milk, and horse fluids. The dimensions of the device were altered to accommodate an E. coli or Listeria lateral flow immunoassay, and using a laser printer, BaDx devices were manufactured to identify E. coli and Listeria. Initial testing with E. coli versions of BaDx indicate that the device will be viable as a portable diagnostic cartridge. The device would be more effective with faster bacteria germination; hence studies were performed the use of rapid germination chemistry. Trials with calcium dipicolinic acid displayed increased cell germination, as shown by control studies using a microplate reader. Upon lyophilization the rapid germination chemistry failed to change growth patterns, indicating that the calcium dipicolinic acid was not solubilized under the conditions tested. Although incompatible with the portable diagnostic device, the experiments proved that the rapid germination chemistry was effective in increasing cell germination.

  14. Evaluate of head loss, sediment value and copper removal in sand media (rapid sand filter

    Directory of Open Access Journals (Sweden)

    Daneshi Navab

    2014-06-01

    Full Text Available Along with the technology development and increasing consumption of water resources, we are experiencing low qualities in the mentioned resources. Copper brings about serious environment al pollution, threatening human health and ecosystem. This metal found variously in water resources and industrial activities. Therefore, it needs to treat the water resources from these excessive amounts. Different methods have used for this reason but the most used method during recent years has been the absorption by economic absorbers such as sand. Rapid sand filters usually used in water and wastewater treatment plants for water clarification. In this research, a single layer gravity rapid sand filter has used to reduce different concentrations of copper. sediment value and head loss arising in filter media is simulated by using combination of Carman-Kozeny, Rose and Gregory models in different discharges of rapid sand filter. Results have shown that with increasing in discharge and decreasing in input copper concentration, arriving time to given head loss, is increasing. In addition, results demonstrated that with increasing in copper concentration in influent, removal efficiency is decreasing somewhat. Results of this research can applied in an appropriate design of rapid sand filter to copper removal, a prediction of rapid sand filter ability to copper removal and an estimation of arising head loss during filter work thus evaluating of time interval backwash. DOI: http://dx.doi.org/10.3126/ije.v3i2.10641 International Journal of the Environment Vol.3(2 2014: 276-286

  15. An operational procedure for rapid flood risk assessment in Europe

    Science.gov (United States)

    Dottori, Francesco; Kalas, Milan; Salamon, Peter; Bianchi, Alessandra; Alfieri, Lorenzo; Feyen, Luc

    2017-07-01

    The development of methods for rapid flood mapping and risk assessment is a key step to increase the usefulness of flood early warning systems and is crucial for effective emergency response and flood impact mitigation. Currently, flood early warning systems rarely include real-time components to assess potential impacts generated by forecasted flood events. To overcome this limitation, this study describes the benchmarking of an operational procedure for rapid flood risk assessment based on predictions issued by the European Flood Awareness System (EFAS). Daily streamflow forecasts produced for major European river networks are translated into event-based flood hazard maps using a large map catalogue derived from high-resolution hydrodynamic simulations. Flood hazard maps are then combined with exposure and vulnerability information, and the impacts of the forecasted flood events are evaluated in terms of flood-prone areas, economic damage and affected population, infrastructures and cities.An extensive testing of the operational procedure has been carried out by analysing the catastrophic floods of May 2014 in Bosnia-Herzegovina, Croatia and Serbia. The reliability of the flood mapping methodology is tested against satellite-based and report-based flood extent data, while modelled estimates of economic damage and affected population are compared against ground-based estimations. Finally, we evaluate the skill of risk estimates derived from EFAS flood forecasts with different lead times and combinations of probabilistic forecasts. Results highlight the potential of the real-time operational procedure in helping emergency response and management.

  16. Rapid response systems.

    Science.gov (United States)

    Lyons, Patrick G; Edelson, Dana P; Churpek, Matthew M

    2018-07-01

    Rapid response systems are commonly employed by hospitals to identify and respond to deteriorating patients outside of the intensive care unit. Controversy exists about the benefits of rapid response systems. We aimed to review the current state of the rapid response literature, including evolving aspects of afferent (risk detection) and efferent (intervention) arms, outcome measurement, process improvement, and implementation. Articles written in English and published in PubMed. Rapid response systems are heterogeneous, with important differences among afferent and efferent arms. Clinically meaningful outcomes may include unexpected mortality, in-hospital cardiac arrest, length of stay, cost, and processes of care at end of life. Both positive and negative interventional studies have been published, although the two largest randomized trials involving rapid response systems - the Medical Early Response and Intervention Trial (MERIT) and the Effect of a Pediatric Early Warning System on All-Cause Mortality in Hospitalized Pediatric Patients (EPOCH) trial - did not find a mortality benefit with these systems, albeit with important limitations. Advances in monitoring technologies, risk assessment strategies, and behavioral ergonomics may offer opportunities for improvement. Rapid responses may improve some meaningful outcomes, although these findings remain controversial. These systems may also improve care for patients at the end of life. Rapid response systems are expected to continue evolving with novel developments in monitoring technologies, risk prediction informatics, and work in human factors. Copyright © 2018 Elsevier B.V. All rights reserved.

  17. The Health and Sport Engagement (HASE) Intervention and Evaluation Project: protocol for the design, outcome, process and economic evaluation of a complex community sport intervention to increase levels of physical activity.

    Science.gov (United States)

    Mansfield, Louise; Anokye, Nana; Fox-Rushby, Julia; Kay, Tess

    2015-10-26

    Sport is being promoted to raise population levels of physical activity for health. National sport participation policy focuses on complex community provision tailored to diverse local users. Few quality research studies exist that examine the role of community sport interventions in raising physical activity levels and no research to date has examined the costs and cost-effectiveness of such provision. This study is a protocol for the design, outcome, process and economic evaluation of a complex community sport intervention to increase levels of physical activity, the Health and Sport Engagement (HASE) project part of the national Get Healthy Get Active programme led by Sport England. The HASE study is a collaborative partnership between local community sport deliverers and sport and public health researchers. It involves designing, delivering and evaluating community sport interventions. The aim is to engage previously inactive people in sustained sporting activity for 1×30 min a week and to examine associated health and well-being outcomes. The study uses mixed methods. Outcomes (physical activity, health, well-being costs to individuals) will be measured by a series of self-report questionnaires and attendance data and evaluated using interrupted time series analysis controlling for a range of sociodemographic factors. Resource use will be identified and measured using diaries, interviews and records and presented alongside effectiveness data as incremental cost-effectiveness ratios and cost-effectiveness acceptability curves. A longitudinal process evaluation (focus groups, structured observations, in-depth interview methods) will examine the efficacy of the project for achieving its aim using the principles of thematic analysis. The results of this study will be disseminated through peer-reviewed publications, academic conference presentations, Sport England and national public health organisation policy conferences, and practice-based case studies

  18. ALMR deployment economic analysis

    International Nuclear Information System (INIS)

    Delene, J.G.; Fuller, L.C.; Hudson, C.R.

    1993-06-01

    This analysis seeks to model and evaluate the economics of the use of Advanced Liquid Metal Reactors (ALMR) as a component of this country's future electricity generation mix. The ALMR concept has the ability to utilize as fuel the fissile material contained in previously irradiated nuclear fuel (i.e., spent fuel). While not a requirement for the successful deployment of ALMR power plant technology, the reprocessing of spent fuel from light water reactors (LWR) is necessary for any rapid introduction of ALMR power plants. In addition, the reprocessing of LWR spent fuel may reduce the number of high level waste repositories needed in the future by burning the long-lived actinides produced in the fission process. With this study, the relative economics of a number of potential scenarios related to these issues are evaluated. While not encompassing the full range of all possibilities, the cases reported here provide an indication of the potential costs, timings, and relative economic attractiveness of ALMR deployment

  19. EFFECTS OF HIGH ECONOMIC IMPORTANCE OF INDUSTRIAL BRANCHES ON HUMAN LIFE QUALITY AND ENVIRONMENT

    OpenAIRE

    Özarslan, Doguş Deniz; Cumbul Altay, Melek; Arabaci, Aliye; Altay, H. Fatih; Sivri, Nüket

    2012-01-01

    Importance of industrialization which has a role in determination of the civilization levels of societies is increasing everyday due to meet rapidly increasing demands. However this process has led up to environmental problems with time and thus effects on quality of human life also brought along. In this study, three sectors were selected among different branches of industry according to their economical importance in Turkey. These sectors are paper, metal and construction chemicals industry...

  20. Cost-effectiveness of healthy eating and/or physical activity promotion in pregnant women at increased risk of gestational diabetes mellitus : Economic evaluation alongside the DALI study, a European multicenter randomized controlled trial

    NARCIS (Netherlands)

    Broekhuizen, Karen; Simmons, David; Devlieger, Roland; van Assche, André; Jans, Goele; Galjaard, Sander; Corcoy, Rosa; Adelantado, Juan M.; Dunne, Fidelma; Desoye, Gernot; Harreiter, Jürgen; Kautzky-Willer, Alexandra; Damm, Peter; Mathiesen, Elisabeth R.; Jensen, Dorte M.; Andersen, Liselotte L.; Lapolla, Annunziata; Dalfra, Maria G.; Bertolotto, Alessandra; Wender-Ozegowska, Ewa; Zawiejska, Agnieszka; Hill, David; Snoek, Frank J.; Jelsma, Judith G.M.; Bosmans, Judith E.; van Poppel, Mireille N.M.; van Dongen, Johanna M.

    2018-01-01

    Background: Gestational diabetes mellitus (GDM) is associated with perinatal health risks to both mother and offspring, and represents a large economic burden. The DALI study is a multicenter randomized controlled trial, undertaken to add to the knowledge base on the effectiveness of interventions

  1. Cost-effectiveness of healthy eating and/or physical activity promotion in pregnant women at increased risk of gestational diabetes mellitus : Economic evaluation alongside the DALI study, a European multicenter randomized controlled trial

    NARCIS (Netherlands)

    Broekhuizen, K. (Karen); D. Simmons (David); R. Devlieger (Roland); A. Van Assche (Andre); G. Jans (Goele); S. Galjaard (Sander); R. Corcoy (Rosa); J.M. Adelantado (Juan M); F. Dunne (Fidelma); G. Desoye (Gernot); J. Harreiter (Jurgen); A. Kautzky-Willer (Alexandra); P. Damm (Peter); E.R. Mathiesen (Elisabeth); D.M. Jensen (Dorte M.); L. Andersen (Liselotte); A. Lapolla (Annunziata); M.G. Dalfra (Maria G.); A. Bertolotto (Alessandra); E. Wender-Ozegowska (Ewa); A. Zawiejska (Agnieszka); D.J. Hill (David); F.J. Snoek (Frank); J.G.M. Jelsma (Judith G. M.); J.E. Bosmans (Judith); M.N. van Poppel (Mireille); van Dongen, J.M. (Johanna M.)

    2018-01-01

    markdownabstract__Background:__ Gestational diabetes mellitus (GDM) is associated with perinatal health risks to both mother and offspring, and represents a large economic burden. The DALI study is a multicenter randomized controlled trial, undertaken to add to the knowledge base on the

  2. Big Social Network Data and Sustainable Economic Development

    Directory of Open Access Journals (Sweden)

    Umit Can

    2017-11-01

    Full Text Available New information technologies have led to the rapid and effective growth of social networks. The amount of data produced by social networks has increased the value of the big data concept, which is one of the popular current phenomena. The immediate or unpredictable effects of a wide array of economic activities on large masses and the reactions to them can be measured by using social media platforms and big data methods. Thus, it would be extremely beneficial to analyze the harmful environmental and social impacts that are caused by unsustainable business applications. As social networks and big data are popular realms currently, their efficient use would be an important factor in sustainable economic development. Accurate analysis of people’s consumption habits and economic tendencies would provide significant advantages to companies. Moreover, unknown consumption factors that affect the economic preferences of individuals can be discovered and economic efficiency can be increased. This study shows that the numerous solution opportunities that are provided by social networks and big data have become significant tools in dynamic policy creation by companies and states, in solving problems related to women’s rights, the environment, and health.

  3. Conservation through the economics lens.

    Science.gov (United States)

    Farley, Joshua

    2010-01-01

    Although conservation is an inherently transdisciplinary issue, there is much to be gained from examining the problem through an economics lens. Three benefits of such an approach are laid out in this paper. First, many of the drivers of environmental degradation are economic in origin, and the better we understand them, the better we can conserve ecosystems by reducing degradation. Second, economics offers us a when-to-stop rule, which is equivalent to a when-to-conserve rule. All economic production is based on the transformation of raw materials provided by nature. As the economic system grows in physical size, it necessarily displaces and degrades ecosystems. The marginal benefits of economic growth are diminishing, and the marginal costs of ecological degradation are increasing. Conceptually, we should stop economic growth and focus on conservation when the two are equal. Third, economics can help us understand how to efficiently and justly allocate resources toward conservation, and this paper lays out some basic principles for doing so. Unfortunately, the field of economics is dominated by neoclassical economics, which builds an analytical framework based on questionable assumptions and takes an excessively disciplinary and formalistic approach. Conservation is a complex problem, and analysis from individual disciplinary lenses can make important contributions to conservation only when the resulting insights are synthesized into a coherent vision of the whole. Fortunately, there are a number of emerging transdisciplines, such as ecological economics and environmental management, that are dedicated to this task.

  4. Skill-based immigration, economic integration, and economic performance

    OpenAIRE

    Aydemir, Abdurrahman

    2014-01-01

    Studies for major immigrant-receiving countries provide evidence on the comparative economic performance of immigrant classes (skill-, kinship-, and humanitarian-based). Developed countries are increasingly competing for high-skilled immigrants, who perform better in the labor market. However, there are serious challenges to their economic integration, which highlights a need for complementary immigration and integration policies.

  5. Effects of Problem Based Economics on High School Economics Instruction

    Science.gov (United States)

    Finkelstein, Neal; Hanson, Thomas

    2011-01-01

    The primary purpose of this study is to assess student-level impacts of a problem-based instructional approach to high school economics. The curriculum approach examined here was designed to increase class participation and content knowledge for high school students who are learning economics. This study tests the effectiveness of Problem Based…

  6. Applied evolutionary economics and economic geography

    NARCIS (Netherlands)

    Frenken, K.

    2007-01-01

    Applied Evolutionary Economics and Economic Geography" aims to further advance empirical methodologies in evolutionary economics, with a special emphasis on geography and firm location. It does so by bringing together a select group of leading scholars including economists, geographers and

  7. Blue Growth and Economics

    Directory of Open Access Journals (Sweden)

    Phoebe eKoundouri

    2015-11-01

    Full Text Available Oceans and seas represent over 70% of the earth's surface. Furthermore, living aquatic resources can provide a significant contribution to food, energy and bio-based products. However, marine ecosystems are subject to increasing pressures and competing usages, resulting from resources over-exploitation and pollution. In order to produce efficient marine management plans, it is essential to consider the total economic value provided by the marine ecosystems. In this review, we are focusing on the Marine Framework Strategy Directive and the European Marine Spatial Planning that are established for the protection and efficient use of the marine area. We present the ecosystem services approach with regards to the marine ecosystem and propose economic methods that capture the marine ecosystem’s total economic value in relation to the opportunity cost of marine space. Values should be used to guide policy makers following the European directives and initiatives.

  8. Increase in healthcare facilities and rapid environmental degradation

    African Journals Online (AJOL)

    user

    The scenario of waste management in many Nigerian cities has been complicated by the non segregation ..... and pathology laboratories, wastes from production of biological, .... Wastes Management – A Handbook for Developing Countries,.

  9. rapid increase in precaution The global financial crisis: origin ...

    African Journals Online (AJOL)

    user

    2010-05-01

    May 1, 2010 ... provoked a global flight on quality, caused firms to cut back on ... despite coordinated easing of monetary policy by governments and trillions ... indicated in the scope of the study, the discussions will be based on financial .... financial investors in decision making, which would overvalue asset prices in.

  10. Contextual background to the rapid increase in migration from ...

    African Journals Online (AJOL)

    user

    Buoyed by a sound economy and under pressure to redress past social ... the government adopted redistributive socialist fiscal policies (UNDP 2008). ... to South Africa, the United Kingdom, Australia, Canada and New Zealand. They ..... For many people, it was no longer worthwhile to go to work when the purchase price.

  11. rapid increase in precaution The global financial crisis: origin ...

    African Journals Online (AJOL)

    user

    2010-05-01

    May 1, 2010 ... loosening of lending standards and the rise of sub prime mortgages. In order to cover the risk of defaults on mortgages, particularly sub prime mortgages, sed credit default swaps. 3. (CDSs). These are. 2 Fannie Mae (Federal National Mortgage Association) is a government-sponsored enterprise (GSE) ...

  12. Economic inequality and economic crisis: a challenge for social workers.

    Science.gov (United States)

    Goldberg, Gertrude Schaffner

    2012-07-01

    To social workers, extreme economic inequality is primarily a violation of social justice, but this article shows how growing economic inequality since the mid-1970s was not only unjust, but also dysfunctional to the U.S. economy and linked to the recent economic crisis with its devastating effects, particularly on the social work clientele. The article identifies interrelated changes in ideology, the market economy, and government policies since the mid-1970s; contrasts the political economy of this period with the preceding post-World War II decades when the trend was toward a "shared prosperity"; and shows how increased economic inequality and political consequences that undermined democracy itself contributed to the economic meltdown. The analysis has implications for the direction of social reform and for broadening the constituency of social movements in pursuit of the social work mission of social justice. How social workers can contribute to such movements and to a reduction of economic and political inequality is explored.

  13. Narrative and Institutional Economics

    Directory of Open Access Journals (Sweden)

    Vyacheslav V. Volchik

    2017-12-01

    Full Text Available This article addresses a range of questions associated with the occurrence of a new field of study – narrative economics, which is considered in the context of modern institutionalism. Pioneering works of R. Shiller, G. Akerlof and D. Snower spotlighted the importance of analyzing narratives and narrative influence when studying economic processes. In this paper, a qualitative study of narratives is seen through the prism of an answer to the question: «How do prescribed narratives influence institutions and change them? ». Narratives have much in common with institutions since very often, explicitly or implicitly, they contain value judgements about social interactions or normative aspects shaping behavioral patterns. The identification of dominating narratives enables us to understand better how institutions influence economic (social action. Repeated interactions among social actors are structured through understanding and learning the rules. Understanding of social rules comes from the language – we articulate and perceive the rules drawing on common narratives. Narratives and institutions are helpful when actors gain knowledge about various forms of social communication. Digital technologies, mass media and social networking sites facilitate the spread of narratives, values and beliefs; this process is characterized by increasing returns. Studying narratives and institutions is crucial for modern economic theory because it helps to improve qualitative and quantitative methods of analyzing empirical evidence and enables researchers to understand complex economic processes.

  14. How Taxes and Spending on Education Influence Economic Growth in Poland

    Directory of Open Access Journals (Sweden)

    Michał Konopczyński

    2014-09-01

    Full Text Available This paper investigates the relationship between economic growth in Poland and four types of taxes and human capital investment. We primarily rely on an exogenous growth model that merges the Mankiw-Romer-Weil model, augmented with learning-by-doing and spillover-effects, with selected elements from the literature on optimal taxation. We demonstrate that in the period 2000-2011, economic growth in Poland was primarily due to a rapid increase in the human capital stock (at a rate of 5% per annum and only secondarily due to the accumulation of productive capital (2.7% annually. Simulations of tax cuts suggest that income taxes and consumption taxes restrict economic growth equally heavily. Simultaneously reducing all tax rates by 5 percentage points (pp in Poland should increase annual GDP growth by approximately 0.4 pp. Increasing spending on education by 1 pp of GDP would increase the growth rate by approximately 0.3 pp.

  15. District heating for increased biogas production. Technical and economical evaluation of district heating as heating source in biogas processes; Fjaerrvaerme foer utoekad biogasproduktion. Teknisk och ekonomisk utvaerdering av fjaerrvaerme foer uppvaermning av biogasprocesser

    Energy Technology Data Exchange (ETDEWEB)

    Lundqvist, Per (AaF-Consult AB, Stockholm (Sweden))

    2009-11-15

    This report presents a technical evaluation, the potential and an economical evaluation of the increased net biogas production by using district heating as energy supply for different types of biogas production units. The study presents generalized results for different plant sizes. The district heating is considered as replacement of the heat produced by burning biogas in a hot-water boiler. Hence more biogas could be available for upgrading to fuel-gas quality to be used in vehicles as a renewable fuel. The study is aimed at biogas producers, district heating and combined heat and power (CHP) companies. Biogas has a composition of mostly methane (about 65 %) and carbon dioxide (about 35 %) and small amounts of other gases e.g. sulphur dioxide (H{sub 2}S). Biogas up-grading is a process where the methane content is increased to about 97 % by removing most of the other gases in e.g. an absorption unit. The Swedish biogas is mainly produced in several sewage treatment plants and some co-digestion units but is also collected from dumps. Biogas is produced by anaerobic microorganisms at temperatures of about 36 and 55 deg C which correspond to the thermal optimum for mesophile and thermophile bacteria respectively. Co-digestion of animal material which e.g. is contained in collected organic household waste has to be pasteurized at 70 deg C for 1h according to EU-regulations. Such regulations may also be introduced to the sludge from municipal sewage treatment plants. Due to the fact that the process temperature is higher than the temperature of the substrate (sludge or organic waste material) as well as the outdoor temperature, both heating of the incoming substrate and compensation of heat losses are required. Traditionally most of the biogas has been burnt to generate the necessary heat for the process and premises at the plant. The excess gas has been burnt in a torch. In recent years the biogas produced in Sweden has found increased use as a renewable vehicle fuel

  16. ECONOMIC SUSTAINABILITY

    Directory of Open Access Journals (Sweden)

    Aurel MARIN

    2013-12-01

    Full Text Available This article aims to highlight the quality of life that depends on necessary, harmonious and simultaneous satisfying of all human needs, instead of „one at a time”, health and economic insecurity being at the very foundation of it. A society that is focused on quality of life will be a society centered on the individual, their needs and aspirations. It needs to offer alternatives and choices of the individual and not to impose models. Coercion of society over the individual is an objective and necessary phenomenon. Its deepening is not, however, as required. Social environment based on quality of life must be characterized by the maximum possible degree of permissiveness in which the individual is educated in its contribution to social awareness.

  17. Is wartime mobilisation a suitable policy model for rapid national climate mitigation?

    International Nuclear Information System (INIS)

    Delina, Laurence L.; Diesendorf, Mark

    2013-01-01

    Climate science suggests that, to have a high probability of limiting global warming to an average temperature increase of 2 °C, global greenhouse gas emissions must peak by 2020 and be reduced to close to zero by 2040. However, the current trend is heading towards at least 4 °C by 2100 and little effective action is being taken. This paper commences the process of developing contingency plans for a scenario in which a sudden major global climate impact galvanises governments to implement emergency climate mitigation targets and programs. Climate activists assert that rapid mitigation is feasible, invoking the scale and scope of wartime mobilisation strategies. This paper draws upon historical accounts of social, technological and economic restructurings in several countries during World War 2 in order to investigate potential applications of wartime experience to radical, rigorous and rapid climate mitigation strategies. We focus on the energy sector, the biggest single contributor to global climate change, in developed and rapidly developing countries. We find that, while wartime experience suggests some potential strategies for rapid climate mitigation in the areas of finance and labour, it also has severe limitations, resulting from its lack of democratic processes. - Highlights: • The paper explores the strengths and weaknesses of using wartime experience as a model for rapid climate mitigation. • Wartime experience suggests some potential strategies for rapid climate mitigation in the areas of finance and labour. • Wartime experience also has severe limitations, resulting from its lack of democratic processes

  18. Economic feasibility of radioactive scrap steel recycling

    International Nuclear Information System (INIS)

    Nichols, F.; Balhiser, R.; Rosholt, D.

    1995-01-01

    In the past, government and commercial nuclear operators treated radioactive scrap steel (RSS) as a liability and disposed of it by burial; this was an accepted and economical solution at that time. Today, environmental concerns about burial are changing the waste disposal picture by (a) causing burial costs to soar rapidly, (b) creating pressure to close existing burial sites, and (c) making it difficult and expensive to open and operate burial facilities. To exacerbate the problem, planned dismantling of nuclear facilities will substantially increase volumes of RSS open-quotes wasteclose quotes over the next 30 yr. This report describes a project with the intention of integrating the current commercial mini-mill approach of recycling uncontaminated steel with radiological controls to design a system that can process contaminated metals at prices significantly below the current processors or burial costs

  19. THE IMPORTANCE OF LAW AND ECONOMICS IN THE CONTEMPORARY ECONOMIC REALITY

    OpenAIRE

    Pomaskow, Joanna

    2015-01-01

    The law and economics movement can improve the functioning of companies doing business in the contemporary, rapidly changing, reality. The tensions between the idea of efficiency and the idea of justice cause difficulties in the application of tools which are proposed by the representatives of the law and economics movement in legal solutions. Economics proposes a new, fresh look at the law, which makes it easier to assess and influence the growth of its transparency. Perspective can therefor...

  20. Rapid world modeling

    International Nuclear Information System (INIS)

    Little, Charles; Jensen, Ken

    2002-01-01

    Sandia National Laboratories has designed and developed systems capable of large-scale, three-dimensional mapping of unstructured environments in near real time. This mapping technique is called rapid world modeling and has proven invaluable when used by prototype systems consisting of sensory detection devices mounted on mobile platforms. These systems can be deployed into previously unmapped environments and transmit real-time 3-D visual images to operators located remotely. This paper covers a brief history of the rapid world modeling system, its implementation on mobile platforms, and the current state of the technology. Applications to the nuclear power industry are discussed. (author)

  1. JINR rapid communications

    International Nuclear Information System (INIS)

    1998-01-01

    The present collection of rapid communications from JINR, Dubna, contains seven separate records on relativistic multiparticle processes in the central rapidity region at asymptotically high energies, a new experimental study of charged K→3π decays, pre-Cherenkov radiation as a phenomenon of 'light barrier', stable S=-2 H dibaryon found in Dubna, calculation of Green functions and gluon top in some unambiguous gauges, a method of a fast selection of inelastic nucleus-nucleus collisions for the CMS experiment and the manifestation of jet quenching in differential distributions of the total transverse energy in nucleus-nucleus collisions

  2. Rapid microbiology - raising awareness.

    Science.gov (United States)

    Bailie, Jonathan

    2016-01-01

    A 'high-level overview' of some of the emerging rapid microbiology technologies designed to help healthcare engineering and infection control teams working in hospitals and other healthcare facilities more rapidly identify potentially hazardous levels of waterborne microorganisms in their water systems, enabling them to take prompt remedial action, and a look at the some of the 'pros and cons' of such testing techniques, was given by Nalco technical director, Howard Barnes, the vice-chair of the Legionella Control Association (LCA), at a recent LCA open day. HEJ editor, Jonathan Bailie, reports.

  3. JINR rapid communications

    International Nuclear Information System (INIS)

    1998-01-01

    The present collection of rapid communications from JINR, Dubna, contains seven separate records on invisible Z-boson width and restrictions on next-to-minimal supersymmetric standard model, cosmic test of honeycomb drift chambers, fission of 209 Bi, 232 Th, 235 U, 238 U and 237 Np in a spallation neutron field, rapid screening of spontaneous and radiation-induced structural changes at the vestigial gene of Drosophila melanogaster by polymerase chain reaction, gamma-ray multiplicities in sub-barrier fission of 226 Th and the decay constants of the scalar and pseudoscalar mesons in the quark models with quasilocal interaction

  4. Temporal trends in BMI in Argentina by socio-economic position and province-level economic development, 2005-2009.

    Science.gov (United States)

    Christine, Paul J; Diez Roux, Ana V; Wing, Jeffrey J; Alazraqui, Marcio; Spinelli, Hugo

    2015-04-01

    We investigated temporal trends in BMI, and assessed hypothesized predictors of trends including socio-economic position (SEP) and province-level economic development, in Argentina. Using multivariable linear regression, we evaluated cross-sectional patterning and temporal trends in BMI and examined heterogeneity in these associations by SEP and province-level economic development with nationally representative samples from Argentina in 2005 and 2009. We calculated mean annual changes in BMI for men and women to assess secular trends. Women, but not men, exhibited a strong cross-sectional inverse association between SEP and BMI, with the lowest-SEP women having an average BMI 2.55 kg/m(2) greater than the highest-SEP women. Analysis of trends revealed a mean annual increase in BMI of 0.19 kg/m(2) and 0.15 kg/m(2) for women and men, respectively, with slightly greater increases occurring in provinces with greater economic growth. No significant heterogeneity in trends existed by individual SEP. BMI is increasing rapidly over time in Argentina irrespective of various sociodemographic characteristics. Higher BMI remains more common in women of lower SEP compared with those of higher SEP.

  5. Obesity and economic environments.

    Science.gov (United States)

    Sturm, Roland; An, Ruopeng

    2014-01-01

    This review summarizes current understanding of economic factors during the obesity epidemic and dispels some widely held, but incorrect, beliefs. Rising obesity rates coincided with increases in leisure time (rather than increased work hours), increased fruit and vegetable availability (rather than a decline in healthier foods), and increased exercise uptake. As a share of disposable income, Americans now have the cheapest food available in history, which fueled the obesity epidemic. Weight gain was surprisingly similar across sociodemographic groups or geographic areas, rather than specific to some groups (at every point in time; however, there are clear disparities). It suggests that if one wants to understand the role of the environment in the obesity epidemic, one needs to understand changes over time affecting all groups, not differences between subgroups at a given time. Although economic and technological changes in the environment drove the obesity epidemic, the evidence for effective economic policies to prevent obesity remains limited. Taxes on foods with low nutritional value could nudge behavior toward healthier diets, as could subsidies/discounts for healthier foods. However, even a large price change for healthy foods could close only part of the gap between dietary guidelines and actual food consumption. Political support has been lacking for even moderate price interventions in the United States and this may continue until the role of environmental factors is accepted more widely. As opinion leaders, clinicians play an important role in shaping the understanding of the causes of obesity. © 2014 American Cancer Society.

  6. As good as it gets : Alberta economic profile and forecast

    International Nuclear Information System (INIS)

    Hirsch, T.

    2006-04-01

    This economic profile and forecast report for the province of Alberta revealed that nearly every sector of the economy is operating at full, or near full capacity. Alberta's strong economy is a result of high energy prices, rapid population growth and rising employment. Increased provincial government spending along with tax reductions for businesses also contribute to a strong economy. However, the the province still faces some economic challenges, including a general labour shortage. Forestry and agriculture are under pressure of low commodity prices and high input costs, and the province has not articulated a long-term strategy for managing non-renewable natural resource revenue. In addition, the provincial economy is highly dependent upon volatile energy prices. Despite these challenges, the report states that the momentum is on the side of continued economic growth in Alberta. The Canada West Foundation is forecasting real growth in the gross domestic product of 5.2 per cent for 2006 and 4.7 per cent for 2007. The strong energy sector is largely responsible for much of Alberta's economic growth. An estimated 20,000 wells will be drilled in the province in 2006, and high oil prices will lead to record drilling and oil sands investment. This report also highlighted the economic activity in other sectors, including manufacturing, tourism, international exports, hi-tech, forestry, agriculture, and construction. Information regarding interprovincial migration and population growth was included along with public finances. 16 figs

  7. Economic growth, ecological economics, and wilderness preservation

    Science.gov (United States)

    Brian Czech

    2000-01-01

    Economic growth is a perennial national goal. Perpetual economic growth and wilderness preservation are mutually exclusive. Wilderness scholarship has not addressed this conflict. The economics profession is unlikely to contribute to resolution, because the neoclassical paradigm holds that there is no limit to economic growth. A corollary of the paradigm is that...

  8. Economic instruments for waste management

    International Nuclear Information System (INIS)

    Malaman, R.

    1991-01-01

    Economic instruments for the implementation of environmental policies distinguish themselves from traditional tools (the 'command and control' type) for the reason that: they influence the costs and the benefits of the economic agents in question; they change the behaviour of the subjects in question in a way that they guarantee behaviour trends less harmful to the environment; they guarantee the assignment of adequate prices to the natural resources that traditionally don't have a price and therefore are consumed excessively by the economic subjects; normally they impose the transfer of economic resources to the disadvantage of the subjects responsible for the phenomena of pollution; certain objective pollution reduction data guarantee the minimization of the social costs of pollution abatement, that is, of the total costs on the economic system in general (economists define this characteristic as the 'static efficiency'); they guarantee what is called in economical jargon, the dynamic efficiency, i.e., in practice, they determine a continuous incentive for the reduction of the emission of the various pollutants and for the realization of the technological innovations that are able to control the pollution; they are more flexible than the instruments of direct regulation, because they leave the subjects a freedom of choice under different price conditions than in the past; they are flexible as well for the reason that the public operator can intervene rapidly to change the way of application

  9. Ecological economics, energy, and sustainable development

    International Nuclear Information System (INIS)

    Peet, J.

    1991-01-01

    Conventional techniques of economics, in different countries, do not normally take proper account of increases in the cost of energy (especially oil) that are expected in the next twenty years, or the rapidly declining ability of the environment to absorb wastes and pollutants, especially those resulting from the use of fossil fuels. Unless these factors are included in political-economic decision-making, and paths for future development adjusted to take account of them, many future development options will be severely damaged. In this paper, it is argued that new decision-making principles are urgently needed, in which societies accept that the physics of the environment are dominant, and the desires of people are subject to physical constraints. When future development options are considered, there is therefore a hierarchy of decision-making. Primary decisions depend upon the physics and ecology of the environment, of development, and of resource utilization. These have to be made before secondary decisions which are mainly ethical, and depend upon social and community values. These are best expressed by people, through adult education and the political process. Only then is it possible to make tertiary decisions, which relate to the allocation of resources. These decisions will depend heavily upon the use of economic tools. Several approaches have been proposed for improving political-economic decision-making. Some concentrate on modifications to markets, so they can incorporate ''externalities''. In other approaches, physical understandings are introduced into policy analyses, in order to indicate the constraints that limit development options. Some important techniques are reviewed, and suggestions are made about better methods of decision-making in the future. (author)

  10. Behavioral economics.

    Science.gov (United States)

    Chambers, David W

    2009-01-01

    It is human nature to overestimate how rational we are, both in general and even when we are trying to be. Such irrationality is not random, and the search for and explanation of patterns of fuzzy thinking is the basis for a new academic discipline known as behavioral economics. Examples are given of some of the best understood of our foibles, including prospect theory, framing, anchoring, salience, confirmation bias, superstition, and ownership. Humans have two cognitive systems: one conscious, deliberate, slow, and rational; the other fast, pattern-based, emotionally tinged, and intuitive. Each is subject to its own kind of error. In the case of rational thought, we tend to exaggerate our capacity; for intuition, we fail to train it or recognize contexts where it is inappropriate. Humans are especially poor at estimating probabilities, or even understanding what they are. It is a common human failing to reason backwards from random outcomes that are favorable to beliefs about our power to predict the future. Five suggestions are offered for thinking within our means.

  11. Economic Issues in Power System Decarbonization

    International Nuclear Information System (INIS)

    Sabolic, D.

    2012-01-01

    Achieving the 80% decrease in carbon-dioxide emissions until 2050, which is the primary goal of the European Union's long-term energy policy, assumes, inter alia, that the electricity part of the system will be able to produce at least 96% of electricity from renewable sources. Moreover, the power system in the widest sense of the word should significantly increase its energy efficiency. Such tremendously ambitious goals, which may as well seem almost unattainable from today's perspective, will certainly require hefty capital investments in plants based on clean technologies, thus, the costs of pollution externalities will not be avoidable anymore. They will have to be bore by the society through substantial increase in energy prices relative to other products and services. Today's subvention schemes, which support current development of renewable sources, will have to be completely abandoned until such a distant future as 2050 is. The power system will have to become self-sustainable in an economic sense. This work pertains to economic challenges which face the power system in a forthcoming processes of rapid decarbonization, as well as to some widely-spread blunders about them.(author)

  12. French Economics of Convention and Economic Sociology

    DEFF Research Database (Denmark)

    Jagd, Søren

    foundation of markets and of money may be an occasion for economic sociology to focus even more on elaborating on the institutional void created by traditional economic theory. A second point is that economic sociology could benefit from the perspective of a plurality of forms of coordination involved......The French Economics of convention tradition has developed to be an influential research tradition situated in the area between economics and sociology. The aim of the paper is to explore some of the themes that may be common to economics of conventions and economic sociology by looking more...... closely into three recent texts from the economics of convention tradition discussing, in slightly different ways, differences and similarities between economics of convention and economic sociology. It is argued that André Orléan’s point that a common aim could be to ‘denaturalise’ the institutional...

  13. Economics of Convention and New Economic Sociology

    DEFF Research Database (Denmark)

    Jagd, Søren

    2007-01-01

    The aim of the article is to explore potential common themes in economic sociology and economics of conventions. The article explores two issues raised by economics of conventions that may be of particular importance to economic sociology. First, the explicit exploration of the consequences...... of a plurality of forms of justification, as elaborated in économie de la grandeur. This perspective was recently taken up in economic sociology by David Stark's introduction of the notion ‘sociology of worth'. The second issue, recently suggested by André Orléan, is the need to denaturalize economic theory...... and economic action to demonstrate the social constructed nature of economic action. It is argued that these two issues demonstrate that a fruitful dialogue is indeed possible between economic sociology and economics of convention and should be encouraged....

  14. AFRICAN JOURNAL OF ECONOMIC REVIEW

    African Journals Online (AJOL)

    Dr Kazungu

    and human capital augmentation and increased exports. It is often ... (1994) report that FDI exerts a positive effect on economic growth, but that there seems to be a threshold level ...... An Unpublished Ph.D. Thesis Submitted to Department of.

  15. AFRICAN JOURNAL OF ECONOMIC REVIEW

    African Journals Online (AJOL)

    Dr Kazungu

    educational and income mobility in Sudan, implying that children from poor .... opening of hundreds of primary and secondary schools, despite economic and political ... The technical and vocational education also increased remarkably.

  16. Economic Developments on Perceived Safety, Violence, and Economic Benefits

    Directory of Open Access Journals (Sweden)

    Anthony Fabio

    2015-01-01

    Full Text Available Background. Emerging research highlights the promise of community- and policy-level strategies in preventing youth violence. Large-scale economic developments, such as sports and entertainment arenas and casinos, may improve the living conditions, economics, public health, and overall wellbeing of area residents and may influence rates of violence within communities. Objective. To assess the effect of community economic development efforts on neighborhood residents’ perceptions on violence, safety, and economic benefits. Methods. Telephone survey in 2011 using a listed sample of randomly selected numbers in six Pittsburgh neighborhoods. Descriptive analyses examined measures of perceived violence and safety and economic benefit. Responses were compared across neighborhoods using chi-square tests for multiple comparisons. Survey results were compared to census and police data. Results. Residents in neighborhoods with the large-scale economic developments reported more casino-specific and arena-specific economic benefits. However, 42% of participants in the neighborhood with the entertainment arena felt there was an increase in crime, and 29% of respondents from the neighborhood with the casino felt there was an increase. In contrast, crime decreased in both neighborhoods. Conclusions. Large-scale economic developments have a direct influence on the perception of violence, despite actual violence rates.

  17. How robust is the relationship between economic freedom and economic growth?

    NARCIS (Netherlands)

    Sturm, JE; De Haan, J

    Using various indicators for economic freedom, it is shown that increases in economic freedom are robustly related to economic growth. This conclusion holds even if the impact of outlying observations is taken into account. The level of economic freedom is not related to growth.

  18. Increasing the complexity of a refinery: a analysis of the economic impacts of the introduction of new process in refineries; O aumento da complexidade de uma refinaria: uma analise dos impactos economicos da introducao de novos processos em refinarias

    Energy Technology Data Exchange (ETDEWEB)

    Fontes, Cristiane M; Seidl, Peter R [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Escola de Quimica

    2008-07-01

    The importance of the refining segment in the oil productive chain turns decision making on production and investment to be made at refineries dependent upon general context of the oil industry. Several technical and economic factors limit the possibilities to be foreseen by the managers. The ultimate goal of a refinery is to meet market demand in a region. Moreover, the type of processed oil and refining techniques will shape the profile of the production of derivatives. In a segment dynamic and full of uncertainties, such as refining, where the type of oil supplied to processing, specifications of products, and their demands, changes in the course of time, how to keep refining margins acceptable? This paper presents the relationship between the characteristics and the use of different kinds of oil, the characteristics of the national market of derivatives, and some characteristics of the refining processes considered in the study. The possible economic impacts that the introduction of different processes can bring to a refinery are analysed and alternatives for expansion are evaluated. To achieve these goals, a methodology for analysis considering the yield of Marlin oil refining for different schemes has been developed. (author)

  19. Navigate the Digital Rapids

    Science.gov (United States)

    Lindsay, Julie; Davis, Vicki

    2010-01-01

    How can teachers teach digital citizenship when the digital landscape is changing so rapidly? How can teachers teach proper online social interactions when the students are outside their classroom and thus outside their control? Will encouraging students to engage in global collaborative environments land teachers in hot water? These are the…

  20. Current challenges in health economic modeling of cancer therapies: a research inquiry.

    Science.gov (United States)

    Miller, Jeffrey D; Foley, Kathleen A; Russell, Mason W

    2014-05-01

    The demand for economic models that evaluate cancer treatments is increasing, as healthcare decision makers struggle for ways to manage their budgets while providing the best care possible to patients with cancer. Yet, after nearly 2 decades of cultivating and refining techniques for modeling the cost-effectiveness and budget impact of cancer therapies, serious methodologic and policy challenges have emerged that question the adequacy of economic modeling as a sound decision-making tool in oncology. We sought to explore some of the contentious issues associated with the development and use of oncology economic models as informative tools in current healthcare decision-making. Our objective was to draw attention to these complex pharmacoeconomic concerns and to promote discussion within the oncology and health economics research communities. Using our combined expertise in health economics research and economic modeling, we structured our inquiry around the following 4 questions: (1) Are economic models adequately addressing questions relevant to oncology decision makers; (2) What are the methodologic limitations of oncology economic models; (3) What guidelines are followed for developing oncology economic models; and (4) Is the evolution of oncology economic modeling keeping pace with treatment innovation? Within the context of each of these questions, we discuss issues related to the technical limitations of oncology modeling, the availability of adequate data for developing models, and the problems with how modeling analyses and results are presented and interpreted. There is general acceptance that economic models are good, essential tools for decision-making, but the practice of oncology and its rapidly evolving technologies present unique challenges that make assessing and demonstrating value especially complex. There is wide latitude for improvement in oncology modeling methodologies and how model results are presented and interpreted. Complex technical and

  1. Conceptual Approaches to the Development of Economic Systems in the Context of Globalization and Regionalization

    Directory of Open Access Journals (Sweden)

    D. I.

    2017-12-01

    Full Text Available Interactions of the national and the global in economic transformations occurring in open economic systems are substantiated. Conceptual approaches to the development of economic systems in the globalization and regionalization context are summed up. It is shown that globalization is a logical consequence of mutual influences and interactions of multiple local transformations in socio-economic systems of various levels, which planetary self-organization generates the new quality of the global economic development. It is concluded that globalization has controversial impact on the transformation capacities of national economic systems that have to operate in the unfavorable condition of the growing instability of the global economic system and rapid integration in the structures with already established economic relations. The heuristic and experimental nature of economic and institutional transformations in these countries is added by splits of national economic systems and disruptions of established production links; the outstripping liberalization of foreign economic relations, creating rather external than internal pressures on national manufacturers and making them less capable to adapt to the competitive environment; the accelerated liberalization of monetary and financial systems, opening up ways to reallocation of capital from the sluggish real sector to the more flexible sector of transactions with currencies and securities; the shrinking regulatory authorities of national governments with respect of trade, competition, tax policies or social welfare; the growing domination of TNC and outflow of productive resources from national economies, important for their self-development, thus making their economic systems structurally primitive; the sharp property differentiation within societies and the increasing shares of population with low incomes.

  2. ANALYSIS OF ECONOMIC RISK IN EUROPEAN INVESTMENT PROJECTS

    Directory of Open Access Journals (Sweden)

    Margareta Stela FLORESCU

    2012-06-01

    Full Text Available Risk is a reality of the economic environment, with consequences which cannot always be foreseen or anticipated. Risk management becomes more stringent as potential exo/endogenous vulnerability factors are rapidly increasing. Identifying risk areas, structuring risk factors and defining their probability, optimal management of resources in order to reduce risk factors, creating alternatives for each high-probability risk factor are part of project risk management. Risk is quantified through probability and incidence and is assessed using quantitative and qualitative methods.

  3. OIL MARKET, NUCLEAR ENERGY CONSUMPTION AND ECONOMIC GROWTH: EVIDENCE FROM EMERGING ECONOMIES

    Directory of Open Access Journals (Sweden)

    Hanan Naser

    2014-04-01

    Full Text Available This paper empirically examines the relationship between oil consumption, nuclear energy consumption, oil price and economic growth in four emerging economies (Russia, China, South Korea, and India over the period from 1965 to 2010. Applying a modified version of the granger causality test developed by Toda and Yamamoto, we find that the level of world crude oil prices (WTI plays a crucial role in determining the economic growth in the investigated countries. The results suggest that there is a unidirectional causality running from real GDP to oil consumption in China and South Korea, while bidirectional relationship between oil consumption and real GDP growth appears in India. Furthermore, the results propose that while nuclear energy stimulates economic growth in both South Korea and India, the rapid increase in China economic growth requires additional usage of nuclear energy.

  4. Economic considerations

    International Nuclear Information System (INIS)

    Bradley, W.G. Jr.

    1987-01-01

    The increasing costs of medical imaging procedures such as MRI and the dwindling capital funds of many hospitals have induced many centers to enter into financial partnerships with their referring physicians. Although limited partnerships may be expedient in the short term, they may constitute a conflict of interest, increasing the potential for unethical self-referral by physician-investors. Even this appearance of conflict of interest may diminish public trust in the medical profession (which is already being perceived as increasingly entrepreneurial). Thus, the initial unbridled enthusiasm for MRI as a miraculous new diagnostic tool has been blunted by concern over its cost and by the increasing potential for unethical behavior in the medical community. This may have contributed to the slower diffusion of MRI technology, which has occurred at only 20% of the rate for diffusion of X-ray computed tomography (CT). To understand this mixed perception of MRI, one must evaluate its efficacy in the context of preexisting CT and increasing controls on costs

  5. Economic conversion: The US experience

    International Nuclear Information System (INIS)

    Williams, R.C.

    1994-01-01

    At the end of the Second World War, our country experienced what economists have called open-quotes The Great Conversionclose quotes or open-quotes The Great Disarmament.close quotes Following that period and until the beginning of the Viet-Nam War was a time marked by economic expansion and boom. Since those years, there have been several periods during which bases were closed and defense spending was slowed. For the communities going through these transitions, again there was economic expansion. A recent survey reports that, within the last 25 years, over 100 communities redeveloped their economic base and experienced, not catastrophy as they expected, but a period of economic growth. Jobs were not lost but nearly doubled. Small businesses and educational institutions multiplied. Building starts accelerated. The survey attributed this economic growth to proper planning, increased awareness of the need for job training and education, diversification of economic activity, and an ownership on the part of the citizens in their collective economic future. The lesson for us should be that realigning our community economic priorities away from such a strong emphasis on military spending and toward a diverse and productive civilian economy brings economic health. We are relearning this lesson in the redevelopment of Lowry Air Force Base and the transition of Rocky Flats Nuclear Plant from a weapons manufacturing mission to one of cleanup

  6. Americans misperceive racial economic equality.

    Science.gov (United States)

    Kraus, Michael W; Rucker, Julian M; Richeson, Jennifer A

    2017-09-26

    The present research documents the widespread misperception of race-based economic equality in the United States. Across four studies ( n = 1,377) sampling White and Black Americans from the top and bottom of the national income distribution, participants overestimated progress toward Black-White economic equality, largely driven by estimates of greater current equality than actually exists according to national statistics. Overestimates of current levels of racial economic equality, on average, outstripped reality by roughly 25% and were predicted by greater belief in a just world and social network racial diversity (among Black participants). Whereas high-income White respondents tended to overestimate racial economic equality in the past, Black respondents, on average, underestimated the degree of past racial economic equality. Two follow-up experiments further revealed that making societal racial discrimination salient increased the accuracy of Whites' estimates of Black-White economic equality, whereas encouraging Whites to anchor their estimates on their own circumstances increased their tendency to overestimate current racial economic equality. Overall, these findings suggest a profound misperception of and unfounded optimism regarding societal race-based economic equality-a misperception that is likely to have any number of important policy implications.

  7. Development of Mobile Educational Game of Economics

    Directory of Open Access Journals (Sweden)

    Indah Rahayu Kurniasari

    2018-05-01

    Full Text Available Along the rapid development of Information and Communication Technology (ICT, learning media are required to undergo renewal. Innovation of learning media that combines modern technology is needed to improve the effectiveness of learning. The research is a Research and Development (R&D. The product result of this research is mobile educational game of economics. This research aims to determine the feasibility of mobile educational game of economics. Media feasibility was assessed based on the results of media-use response questionnaires that given to experts and students. Expert validation result showed that mobile educational game of economics achieved very good judgment. The assessment questionnaires result from the student also stated that the quality and effectiveness of mobile educational game of economics were very good. So, the research concluded that mobile educational game of economics worthy to be used as a media of economics learning.

  8. Economic policy uncertainty index and economic activity: what causes what?

    Directory of Open Access Journals (Sweden)

    Ivana Lolić

    2017-01-01

    Full Text Available This paper is a follow-up on the Economic Policy Uncertainty (EPU index, developed in 2011 by Baker, Bloom, and Davis. The principal idea of the EPU index is to quantify the level of uncertainty in an economic system, based on three separate pillars: news media, number of federal tax code provisions expiring in the following years, and disagreement amongst professional forecasters on future tendencies of relevant macroeconomic variables. Although the original EPU index was designed and published for the US economy, it had instantly caught the attention of numerous academics and was rapidly introduced in 15 countries worldwide. Extensive academic debate has been triggered on the importance of economic uncertainty relating to the intensity and persistence of the recent crisis. Despite the intensive (mostly politically-motivated debate, formal scientific confirmation of causality running from the EPU index to economic activity has not followed. Moreover, empirical literature has completely failed to conduct formal econometric testing of the Granger causality between the two mentioned phenomena. This paper provides an estimation of the Toda-Yamamoto causality test between the EPU index and economic activity in the USA and several European countries. The results do not provide a general conclusion: causality seems to run in both directions only for the USA, while only in one direction for France and Germany. Having taken into account the Great Recession of 2008, the main result does not change, therefore casting doubt on the index methodology and overall media bias.

  9. Decision Making under Ecological Regime Shift: An Experimental Economic Approach

    OpenAIRE

    Kawata, Yukichika

    2011-01-01

    Environmental economics postulates the assumption of homo economicus and presumes that externality occurs as a result of the rational economic activities of economic agents. This paper examines this assumption using an experimental economic approach in the context of regime shift, which has been receiving increasing attention. We observe that when externality does not exist, economic agents (subjects of experimemt) act economically rationally, but when externality exists, economic agents avoi...

  10. Rapid road repair vehicle

    Science.gov (United States)

    Mara, Leo M.

    1998-01-01

    Disclosed is a rapid road repair vehicle capable of moving over a surface to be repaired at near normal posted traffic speeds to scan for and find an the high rate of speed, imperfections in the pavement surface, prepare the surface imperfection for repair by air pressure and vacuum cleaning, applying a correct amount of the correct patching material to effect the repair, smooth the resulting repaired surface, and catalog the location and quality of the repairs for maintenance records of the road surface. The rapid road repair vehicle can repair surface imperfections at lower cost, improved quality, at a higher rate of speed than was was heretofor possible, with significantly reduced exposure to safety and health hazards associated with this kind of road repair activities in the past.

  11. Rapidly processable radiographic material

    International Nuclear Information System (INIS)

    Brabandere, L.A. de; Borginon, H.A.; Pattyn, H.A.; Pollet, R.J.

    1981-01-01

    A new rapidly processable radiographic silver halide material is described for use in mammography and non-destructive testing of industrial materials. The radiographic material is used for direct exposure to penetrating radiation without the use of fluorescent-intensifying screens. It consists of a transparent support with a layer of hydrophilic colloid silver halide emulsion on one or both sides. Examples of the preparation of three different silver halide emulsions are given including the use of different chemical sensitizers. These new radiographic materials have good resistance to the formation of pressure marks in rapid processing apparatus and they have improved sensitivity for direct exposure to penetrating radiation compared to conventional radiographic emulsions. (U.K.)

  12. Rapid manufacturing for microfluidics

    CSIR Research Space (South Africa)

    Land, K

    2012-10-01

    Full Text Available for microfluidics K. LAND, S. HUGO, M MBANJWA, L FOURIE CSIR Materials Science and Manufacturing P O Box 395, Pretoria 0001, SOUTH AFRICA Email: kland@csir.co.za INTRODUCTION Microfluidics refers to the manipulation of very small volumes of fluid.... Microfluidics is at the forefront of developing solutions for drug discovery, diagnostics (from glucose tests to malaria and TB testing) and environmental diagnostics (E-coli monitoring of drinking water). In order to quickly implement new designs, a rapid...

  13. Economics and the question of low-grade heat

    International Nuclear Information System (INIS)

    Gorbet, F.W.

    1976-01-01

    This paper examines, from the viewpoint of an economist, the issues involved in the increased waste heat production generated by the rapid acceleration of electrical production and nuclear generation. It reviews some of the literature on low-grade heat - its economic considerations and ecological impact - and examines the applicability of the traditional type of analytical decision tool (cost/benefit analysis) to the efficient design of heat rejection systems. It is recognized that decisions should be made on the basis of social costs and benefits as well as purely monetary considerations. The validity and shortcomings of cost/benefit analysis are presented. It is concluded that, for energy policy planning and waste heat management, economic feasibility studies should lay out the options together with the costs and risks. (author)

  14. Tiber Personal Rapid Transit

    Directory of Open Access Journals (Sweden)

    Diego Carlo D'agostino

    2011-02-01

    Full Text Available The project “Tiber Personal Rapid Transit” have been presented by the author at the Rome City Vision Competition1 2010, an ideas competition, which challenges architects, engineers, designers, students and creatives individuals to develop visionary urban proposals with the intention of stimulating and supporting the contemporary city, in this case Rome. The Tiber PRT proposal tries to answer the competition questions with the definition of a provocative idea: a Personal Rapid transit System on the Tiber river banks. The project is located in the central section of the Tiber river and aims at the renewal of the river banks with the insertion of a Personal Rapid Transit infrastructure. The project area include the riverbank of Tiber from Rome Transtevere RFI station to Piazza del Popolo, an area where main touristic and leisure attractions are located. The intervention area is actually no used by the city users and residents and constitute itself a strong barrier in the heart of the historic city.

  15. Rapid MR imaging

    International Nuclear Information System (INIS)

    Edelman, R.R.; Buxton, R.B.; Brady, T.J.

    1988-01-01

    Conventional magnetic resonance (MR) imaging methods typically require several minutes to produce an image, but the periods of respiration, cardiac motion and peristalsis are on the order of seconds or less. The need to reduce motion artifact, as well as the need to reduce imaging time for patient comfort and efficiency, have provided a strong impetus for the development of rapid imaging methods. For abdominal imaging, motion artifacts due to respiration can be significantly reduced by collecting the entire image during one breath hold. For other applications, such as following the kinetics of administered contrast agents, rapid imaging is essential to achieve adequate time resolution. A shorter imaging time entails a cost in image signal/noise (S/N), but improvements in recent years in magnet homogeneity, gradient and radiofrequency coil design have led to steady improvements in S/N and consequently in image quality. For many chemical applications the available S/N is greater than needed, and a trade-off of lower S/N for a shorter imaging time is acceptable. In this chapter, the authors consider the underlying principles of rapid imaging as well as clinical applications of these methods. The bulk of this review concentrates on short TR imaging, but methods that provide for a more modest decrease in imaging time as well as or those that dramatically shorten the imaging time to tens of milliseconds are also discussed

  16. Malaysian Economic Development: Looking Backwards and Forward

    OpenAIRE

    Hal Hill

    2010-01-01

    This paper provides an analytical and forward-looking overview of Malaysian economic development. Looking back over its 53 years of Independence, we identify the key stylized facts to include the country's generally rapid economic growth and structural change; its consistent openness, especially for merchandize trade and foreign direct investment; its creditable record of macroeconomic management; its consistently high inequality, in spite of the developing world's most consistently implement...

  17. Population, poverty and economic development.

    Science.gov (United States)

    Sinding, Steven W

    2009-10-27

    Economists, demographers and other social scientists have long debated the relationship between demographic change and economic outcomes. In recent years, general agreement has emerged to the effect that improving economic conditions for individuals generally lead to lower birth rates. But, there is much less agreement about the proposition that lower birth rates contribute to economic development and help individuals and families to escape from poverty. The paper examines recent evidence on this aspect of the debate, concludes that the burden of evidence now increasingly supports a positive conclusion, examines recent trends in demographic change and economic development and argues that the countries representing the last development frontier, those of Sub-Saharan Africa, would be well advised to incorporate policies and programmes to reduce high fertility in their economic development strategies.

  18. Rapidly curable electrically conductive clear coatings

    Energy Technology Data Exchange (ETDEWEB)

    Bowman, Mark P.; Anderson, Lawrence G.; Post, Gordon L.

    2018-01-16

    Rapidly curable electrically conductive clear coatings are applied to substrates. The electrically conductive clear coating includes to clear layer having a resinous binder with ultrafine non-stoichiometric tungsten oxide particles dispersed therein. The clear coating may be rapidly cured by subjecting the coating to infrared radiation that heats the tungsten oxide particles and surrounding resinous binder. Localized heating increases the temperature of the coating to thereby thermally cure the coating, while avoiding unwanted heating of the underlying substrate.

  19. Changing economics

    International Nuclear Information System (INIS)

    Moxon, Suzanne

    1998-01-01

    The policy of the World Bank with regard to the funding of hydro schemes is questioned. Following evidence of the support given by the World Bank to many hydro schemes in the past 30 years, the reasons for the cutbacks in the 1990s are queried. A spokesman for the World Bank discusses the decline in funding. The increasing importance of environmental and social issues was a major factor in the Bank supporting the formation of the World Commission on dams in 1997. The Bank's spokesman asked if hydro can modernise itself and can it compete with other sources of energy in terms of cost and environmental impact. (UK)

  20. Economic Sociology and Economics of Convention

    DEFF Research Database (Denmark)

    Jagd, Søren

    This paper is part of a larger exploration of the French Economics of Convention tradition. The aim of the paper is to explore potential themes of common interest to economic sociology and Economics of Conventions. The paper is in two parts. First, I summarise the main theoretical features of EC...... the institutional framework of social action. Second, I explore two issues raised by economics of conventions that may be particularly important to consider for economic sociology. The first issue is the explicit exploration of the consequences of a plurality of forms of justification suggested by Luc Boltanski...... and Laurent Thévenot in ‘économie de la grandeur’. This perspective has already been taken up in economic sociology in David Stark’s notion of a ‘Sociology of Worth’. The second issue, recently suggested by André Orléan, is the need to denaturalise economic theory and economic action to demonstrate the social...