WorldWideScience

Sample records for rapidly developing research

  1. Research and Development of Rapid Design Systems for Aerospace Structure

    Science.gov (United States)

    Schaeffer, Harry G.

    1999-01-01

    This report describes the results of research activities associated with the development of rapid design systems for aerospace structures in support of the Intelligent Synthesis Environment (ISE). The specific subsystems investigated were the interface between model assembly and analysis; and, the high performance NASA GPS equation solver software system in the Windows NT environment on low cost high-performance PCs.

  2. EasyInterface: A toolkit for rapid development of GUIs for research prototype tools

    OpenAIRE

    Doménech, Jesús; Genaim, Samir; Johnsen, Einar Broch; Schlatte, Rudolf

    2017-01-01

    In this paper we describe EasyInterface, an open-source toolkit for rapid development of web-based graphical user interfaces (GUIs). This toolkit addresses the need of researchers to make their research prototype tools available to the community, and integrating them in a common environment, rapidly and without being familiar with web programming or GUI libraries in general. If a tool can be executed from a command-line and its output goes to the standard output, then in few minutes one can m...

  3. Developing biomarkers in mood disorders research through the use of rapid-acting antidepressants.

    Science.gov (United States)

    Niciu, Mark J; Mathews, Daniel C; Nugent, Allison C; Ionescu, Dawn F; Furey, Maura L; Richards, Erica M; Machado-Vieira, Rodrigo; Zarate, Carlos A

    2014-04-01

    An impediment to progress in mood disorders research is the lack of analytically valid and qualified diagnostic and treatment biomarkers. Consistent with the National Institute of Mental Health (NIMH)'s Research Domain Criteria (RDoC) initiative, the lack of diagnostic biomarkers has precluded us from moving away from a purely subjective (symptom-based) toward a more objective diagnostic system. In addition, treatment response biomarkers in mood disorders would facilitate drug development and move beyond trial-and-error toward more personalized treatments. As such, biomarkers identified early in the pathophysiological process are proximal biomarkers (target engagement), while those occurring later in the disease process are distal (disease pathway components). One strategy to achieve this goal in biomarker development is to increase efforts at the initial phases of biomarker development (i.e. exploration and validation) at single sites with the capability of integrating multimodal approaches across a biological systems level. Subsequently, resultant putative biomarkers could then undergo characterization and surrogacy as these latter phases require multisite collaborative efforts. We have used multimodal approaches - genetics, proteomics/metabolomics, peripheral measures, multimodal neuroimaging, neuropsychopharmacological challenge paradigms and clinical predictors - to explore potential predictor and mediator/moderator biomarkers of the rapid-acting antidepressants ketamine and scopolamine. These exploratory biomarkers may then be used for a priori stratification in larger multisite controlled studies during the validation and characterization phases with the ultimate goal of surrogacy. In sum, the combination of target engagement and well-qualified disease-related measures are crucial to improve our pathophysiological understanding, personalize treatment selection, and expand our armamentarium of novel therapeutics. © 2013 Wiley Periodicals, Inc.

  4. The use of an automated flight test management system in the development of a rapid-prototyping flight research facility

    Science.gov (United States)

    Duke, Eugene L.; Hewett, Marle D.; Brumbaugh, Randal W.; Tartt, David M.; Antoniewicz, Robert F.; Agarwal, Arvind K.

    1988-01-01

    An automated flight test management system (ATMS) and its use to develop a rapid-prototyping flight research facility for artificial intelligence (AI) based flight systems concepts are described. The ATMS provides a flight test engineer with a set of tools that assist in flight planning and simulation. This system will be capable of controlling an aircraft during the flight test by performing closed-loop guidance functions, range management, and maneuver-quality monitoring. The rapid-prototyping flight research facility is being developed at the Dryden Flight Research Facility of the NASA Ames Research Center (Ames-Dryden) to provide early flight assessment of emerging AI technology. The facility is being developed as one element of the aircraft automation program which focuses on the qualification and validation of embedded real-time AI-based systems.

  5. Rapid development of image analysis research tools: Bridging the gap between researcher and clinician with pyOsiriX.

    Science.gov (United States)

    Blackledge, Matthew D; Collins, David J; Koh, Dow-Mu; Leach, Martin O

    2016-02-01

    We present pyOsiriX, a plugin built for the already popular dicom viewer OsiriX that provides users the ability to extend the functionality of OsiriX through simple Python scripts. This approach allows users to integrate the many cutting-edge scientific/image-processing libraries created for Python into a powerful DICOM visualisation package that is intuitive to use and already familiar to many clinical researchers. Using pyOsiriX we hope to bridge the apparent gap between basic imaging scientists and clinical practice in a research setting and thus accelerate the development of advanced clinical image processing. We provide arguments for the use of Python as a robust scripting language for incorporation into larger software solutions, outline the structure of pyOsiriX and how it may be used to extend the functionality of OsiriX, and we provide three case studies that exemplify its utility. For our first case study we use pyOsiriX to provide a tool for smooth histogram display of voxel values within a user-defined region of interest (ROI) in OsiriX. We used a kernel density estimation (KDE) method available in Python using the scikit-learn library, where the total number of lines of Python code required to generate this tool was 22. Our second example presents a scheme for segmentation of the skeleton from CT datasets. We have demonstrated that good segmentation can be achieved for two example CT studies by using a combination of Python libraries including scikit-learn, scikit-image, SimpleITK and matplotlib. Furthermore, this segmentation method was incorporated into an automatic analysis of quantitative PET-CT in a patient with bone metastases from primary prostate cancer. This enabled repeatable statistical evaluation of PET uptake values for each lesion, before and after treatment, providing estaimes maximum and median standardised uptake values (SUVmax and SUVmed respectively). Following treatment we observed a reduction in lesion volume, SUVmax and SUVmed for

  6. Developing a spinal cord injury research strategy using a structured process of evidence review and stakeholder dialogue. Part I: rapid review of SCI prioritisation literature.

    Science.gov (United States)

    Bragge, P; Piccenna, L; Middleton, J W; Williams, S; Creasey, G; Dunlop, S; Brown, D; Gruen, R L

    2015-10-01

    This is a rapid evidence review. The objective of this study was to gain an overview of the volume, nature and findings of studies regarding priorities for spinal cord injury (SCI) research. A worldwide literature search was conducted. Six medical literature databases and Google Scholar were searched for reviews in which the primary aim was to identify SCI research priorities. Two systematic reviews were identified-one of quantitative and one of qualitative studies. The quality of the reviews was variable. Collectively, the reviews identified 31 primary studies; 24 quantitative studies totalling 5262 participants and 7 qualitative studies totalling 120 participants. Despite the difference in research paradigms, there was convergence in review findings in the areas of body impairments and relationships. The vast majority of literature within the reviews focused on the SCI patient perspective. The reviews inform specific research topics and highlight other important research considerations, most notably those pertaining to SCI patients' perspectives on quality of life, which may be of use in determining meaningful research outcome measures. The views of other SCI research stakeholders such as researchers, clinicians, policymakers, funders and carers would help shape a bigger picture of SCI research priorities, ultimately optimising research outputs and translation into clinical practice and health policy change. Review findings informed subsequent activities in developing a regional SCI research strategy, as described in two companion papers. This project was funded by the Victorian Transport Accident Commission and the Australian and New Zealand SCI Network.

  7. Rapidly developing market regions : Brazil

    International Nuclear Information System (INIS)

    Britto, A.

    1997-01-01

    Brazil and the State of Rio Grande do Sul are experiencing a period of rapid industrial development. Global investment has been forecast to reach $240 billion over the next five to seven years. This level of development is likely to result in a sharp increase in the consumption of plastic products made from olefins and from aromatic products. Accordingly, Copesul, the centre of raw materials for the State complex, is expected to increase its production of ethane from 685 tonnes to 1.13 million tonnes after 1999. The government has established a program of incentives to stimulate investment in third generation industries. Also, the State petrochemical industry has been rendered more competitive as a result of the purchase of the latest generation equipment. The principal challenges that exist for the petrochemical industry in Brazil and for that matter, around the world, are to reduce production costs and to preserve the natural environment. Another challenge, also world-wide, is to address the issue of plastic residues and to eliminate such residues through plastic recycling programs

  8. Molecular tools for bathing water assessment in Europe: Balancing social science research with a rapidly developing environmental science evidence-base.

    Science.gov (United States)

    Oliver, David M; Hanley, Nick D; van Niekerk, Melanie; Kay, David; Heathwaite, A Louise; Rabinovici, Sharyl J M; Kinzelman, Julie L; Fleming, Lora E; Porter, Jonathan; Shaikh, Sabina; Fish, Rob; Chilton, Sue; Hewitt, Julie; Connolly, Elaine; Cummins, Andy; Glenk, Klaus; McPhail, Calum; McRory, Eric; McVittie, Alistair; Giles, Amanna; Roberts, Suzanne; Simpson, Katherine; Tinch, Dugald; Thairs, Ted; Avery, Lisa M; Vinten, Andy J A; Watts, Bill D; Quilliam, Richard S

    2016-02-01

    The use of molecular tools, principally qPCR, versus traditional culture-based methods for quantifying microbial parameters (e.g., Fecal Indicator Organisms) in bathing waters generates considerable ongoing debate at the science-policy interface. Advances in science have allowed the development and application of molecular biological methods for rapid (~2 h) quantification of microbial pollution in bathing and recreational waters. In contrast, culture-based methods can take between 18 and 96 h for sample processing. Thus, molecular tools offer an opportunity to provide a more meaningful statement of microbial risk to water-users by providing near-real-time information enabling potentially more informed decision-making with regard to water-based activities. However, complementary studies concerning the potential costs and benefits of adopting rapid methods as a regulatory tool are in short supply. We report on findings from an international Working Group that examined the breadth of social impacts, challenges, and research opportunities associated with the application of molecular tools to bathing water regulations.

  9. Automated rapid chemistry in heavy element research

    International Nuclear Information System (INIS)

    Schaedel, M.

    1994-01-01

    With the increasingly short half-lives of the heavy element isotopes in the transition region from the heaviest actinides to the transactinide elements the demand for automated rapid chemistry techniques is also increasing. Separation times of significantly less than one minute, high chemical yields, high repetition rates, and an adequate detection system are prerequisites for many successful experiments in this field. The development of techniques for separations in the gas phase and in the aqueous phase for applications of chemical or nuclear studies of the heaviest elements are briefly outlined. Typical examples of results obtained with automated techniques are presented for studies up to element 105, especially those obtained with the Automated Rapid Chemistry Apparatus, ARCA. The prospects to investigate the properties of even heavier elements with chemical techniques are discussed

  10. The challenges of rapid urbanization on sustainable development of ...

    African Journals Online (AJOL)

    The challenges of rapid urbanization on sustainable development of Nyanya, Federal Capital ... PROMOTING ACCESS TO AFRICAN RESEARCH ... unaffordable health care facilities, poor environmental health and traffic congestion on the ...

  11. Design and Development of a Rapid Research, Design, and Development Platform for In-Situ Testing of Tools and Concepts for Trajectory-Based Operations

    Science.gov (United States)

    Underwood, Matthew C.

    2017-01-01

    To provide justification for equipping a fleet of aircraft with avionics capable of supporting trajectory-based operations, significant flight testing must be accomplished. However, equipping aircraft with these avionics and enabling technologies to communicate the clearances required for trajectory-based operations is cost-challenging using conventional avionics approaches. This paper describes an approach to minimize the costs and risks of flight testing these technologies in-situ, discusses the test-bed platform developed, and highlights results from a proof-of-concept flight test campaign that demonstrates the feasibility and efficiency of this approach.

  12. Rapid web development using AJAX and Python

    Energy Technology Data Exchange (ETDEWEB)

    Dolgert, A; Gibbons, L; Kuznetsov, V [Cornell University, Ithaca, NY 14853 (United States)], E-mail: vkuznet@gmail.com

    2008-07-15

    We discuss the rapid development of a large scale data discovery service for the CMS experiment using modern AJAX techniques and the Python language. To implement a flexible interface capable of accommodating several different versions of the DBS database, we used a 'stack' approach. Asynchronous JavaScript and XML (AJAX) together with an SQL abstraction layer, template engine, code generation tool and dynamic queries provide powerful tools for constructing interactive interfaces to large amounts of data. We show how the use of these tools, with rapid development in a modern scripting language, improved the scalability and usability of the the search interface for different user communities.

  13. Rapid web development using AJAX and Python

    International Nuclear Information System (INIS)

    Dolgert, A; Gibbons, L; Kuznetsov, V

    2008-01-01

    We discuss the rapid development of a large scale data discovery service for the CMS experiment using modern AJAX techniques and the Python language. To implement a flexible interface capable of accommodating several different versions of the DBS database, we used a 'stack' approach. Asynchronous JavaScript and XML (AJAX) together with an SQL abstraction layer, template engine, code generation tool and dynamic queries provide powerful tools for constructing interactive interfaces to large amounts of data. We show how the use of these tools, with rapid development in a modern scripting language, improved the scalability and usability of the the search interface for different user communities

  14. Lessons learned from Rapid Response Research on wildland fires

    Science.gov (United States)

    Leigh Lentile; Penny Morgan; Colin Hardy; Andrew Hudak; Robert Means; Roger Ottmar; Peter Robichaud; Elaine Sutherland; Frederick Way; Sarah Lewis

    2007-01-01

    In recent years, more researchers are collecting data either on active wildfires or immediately after wildfire occurrence. Known as Rapid Response Research, this important undertaking provides real-time information, useful data, and improved tools for managers.

  15. Ada and the rapid development lifecycle

    Science.gov (United States)

    Deforrest, Lloyd; Gref, Lynn

    1991-01-01

    JPL is under contract, through NASA, with the US Army to develop a state-of-the-art Command Center System for the US European Command (USEUCOM). The Command Center System will receive, process, and integrate force status information from various sources and provide this integrated information to staff officers and decision makers in a format designed to enhance user comprehension and utility. The system is based on distributed workstation class microcomputers, VAX- and SUN-based data servers, and interfaces to existing military mainframe systems and communication networks. JPL is developing the Command Center System utilizing an incremental delivery methodology called the Rapid Development Methodology with adherence to government and industry standards including the UNIX operating system, X Windows, OSF/Motif, and the Ada programming language. Through a combination of software engineering techniques specific to the Ada programming language and the Rapid Development Approach, JPL was able to deliver capability to the military user incrementally, with comparable quality and improved economies of projects developed under more traditional software intensive system implementation methodologies.

  16. Rapidly developing marketing regions : Southeast Asia

    International Nuclear Information System (INIS)

    Howe, J.

    1997-01-01

    The risks and opportunities in the rapidly developing markets in Southeast Asia, China in particular, were discussed. It was asserted that no other region in the world can match the long-term market opportunities that China and Southeast Asia promise. The forces driving the economic development in Southeast Asia were described, including the great potential the region holds for the petrochemical industry. Graphs showing total polyethylene production vs. demand for year 2005 were included as illustrative examples. By 2005, China is projected to be importing almost one-half of the products it consumes. Every country with excess capacity will supply China with polyethylene. The political uncertainties that makes doing business in the region a high risk undertaking were reviewed, along with other risks relevant to the petrochemical industry such as (1) high capital costs, (2) over-building to the point that there is more supply than demand for the product, (3) low-cost producers may drive down prices to maintain market share, and (4) the uncertain nature of projections regarding economic growth and (5) inflated estimates of demand for petrochemicals. 1 tab., 4 figs

  17. Africa: rapid population increase retards development.

    Science.gov (United States)

    1993-10-01

    The Organization of African Unity (OAU), the African Development Bank (ADB) and the UN Economic Commission for Africa (ECA) have criticized African governments for not taking the problem of unchecked population growth seriously enough. "Until recently most African governments did not view rapid population growth as a matter for concern," said the OAU assistant secretary-general for political affairs, Machivenyika Mapuranga, at a seminar on 'population and development'. The OAU estimates that an annual average population increase of 3.1% far outstrips Africa's economic growth, which in 1992 was less than 1%. Mapuranga acknowledged that cutting the population increase is an uphill struggle, especially among rural communities. African agriculture is largely labor intensive, sustained by smallholders, which encourages farmers to have more children. Like other wage earners, African farmers look to support from their family when they grow old and, for that reason, the number of children also counts. But with agricultural production growing at an average annual rate of 2.5%, self-sufficiency in food remains an elusive goal. Cities in sub-Saharan Africa are growing much faster than the overall rate of population increase of 3.1% per year. Between 1980 and 1988 the region's urban population increased at the rate of 6.9% a year. Urban areas now account for nearly 30% of the sub-Saharan Africa population, currently put at 680 million. By 2025, approximately 700 million people are expected to live in urban areas. Despite migration to towns, the rural population is expected to rise more than 68%, reaching over 590 million. full text

  18. The Rapid Forensic Evaluation of Microbes in Biodefense Research Program Will Develop a Rapid Screening and Detection System for Multiple Bio-Threat (BT) Agents for the Department of Defense

    Science.gov (United States)

    2012-05-31

    forensic analysis of microbes. The naturally occurring fungus Rhizoctonia solani (a common inhabitant of the soil ecosystem) was used to experiment...Triangle Park, NC 27709-2211 15. SUBJECT TERMS Rhizoctonia solani, dsRNA, biosensor, proteomics , genomics Dr. Bharathan Narayanaswamy, Dr. Seema Bharathan...naturally occurring fungus Rhizoctonia solani (a common inhabitant of the soil ecosystem) was used to experiment, develop, optimize and validate bio

  19. Is rapid development of nuclear power purposeful

    Energy Technology Data Exchange (ETDEWEB)

    1977-01-01

    The questions of the development of nuclear energy are discussed with regard to the efficacy of investments. The results are given of studies carried out at the nuclear research institute in Juelich in the FRG. At the estimated 25 years' service-life of the reactor and 0.2% uranium concentration in ore the following results were obtained: Total energy consumption for the construction and operation of a light water reactor power plant makes up 4.6% of the total power production, and in high-temperature reactors it amounts to 3.5%, both with uranium enrichment by the diffusion process. In uranium enrichment by centrifugal technology, consumption drops to 1.25% for LWRms and to 0.9% for high-temperature reactors, in fast breeder reactors it makes up only 0.8% of the total power production of the nuclear power plant. The period during which a nuclear power plant produces the amount of power consumed in construction and operation is 1.2 to 2.5 months which makes it less costly and more economical than any power plant burning coal minus the negative environmental impacts of such power plants.

  20. LIDAR Research & Development Lab

    Data.gov (United States)

    Federal Laboratory Consortium — The LIDAR Research and Development labs are used to investigate and improve LIDAR components such as laser sources, optical signal detectors and optical filters. The...

  1. Photovoltaic research and development

    CSIR Research Space (South Africa)

    Cummings, F

    2009-09-01

    Full Text Available Photovoltaic (PV) is the direct conversion of sunlight into electrical energy through a solar cell. This presentation consists of an introduction to photovoltaics, the South African PV research roadmap, a look at the CSIR PV research and development...

  2. Space biology research development

    Science.gov (United States)

    Bonting, Sjoerd L.

    1993-01-01

    The purpose of the Search for Extraterrestrial Intelligence (SETI) Institute is to conduct and promote research related activities regarding the search for extraterrestrial life, particularly intelligent life. Such research encompasses the broad discipline of 'Life in the Universe', including all scientific and technological aspects of astronomy and the planetary sciences, chemical evolution, the origin of life, biological evolution, and cultural evolution. The primary purpose was to provide funding for the Principal Investigator to collaborate with the personnel of the SETI Institute and the NASA-Ames Research center in order to plan and develop space biology research on and in connection with Space Station Freedom; to promote cooperation with the international partners in the space station; to conduct a study on the use of biosensors in space biology research and life support system operation; and to promote space biology research through the initiation of an annual publication 'Advances in Space Biology and Medicine'.

  3. [Rapid development of cosmetic medicine in China].

    Science.gov (United States)

    Lu, Kaihua; Pan, Baohua; Xia, Wei

    2006-04-01

    To review and summarize the development during the last 20 years and the current status of cosmetic medicine, i.e., cosmetic surgery, in China, for the healthier development of this specialty in the future. Literature concerned was reviewed, including conference abstracts, papers, and publications, and the present status and problems were analyzed. Cosmetic medicine was recognized as an independent specialty and gained its clear definition. The development of cosmetic medicine is an inevitable trend of the changing medical modules and the developing science and civilization. This trend fulfilled the need of the people. The related problems consisted of a high complication rate, confusion of management, and insufficient specific knowledge in part of the providers. The development of cosmetic medicine is an inevitable trend of the civilization development. For the healthy development of this specialty, scientific management and systemic education for the providers are crucial. Only those who have the plastic surgery background are able to participate in this practice.

  4. Modular Infrastructure for Rapid Flight Software Development

    Science.gov (United States)

    Pires, Craig

    2010-01-01

    This slide presentation reviews the use of modular infrastructure to assist in the development of flight software. A feature of this program is the use of model based approach for application unique software. A review of two programs that this approach was use on are: the development of software for Hover Test Vehicle (HTV), and Lunar Atmosphere and Dust Environment Experiment (LADEE).

  5. Practical implications of rapid development methodologies

    CSIR Research Space (South Africa)

    Gerber, A

    2007-11-01

    Full Text Available as the acceleration of the system development phases through an iterative construction approach. These methodologies also claim to manage the changing nature of requirements. However, during the development of large and complex systems by a small and technically...

  6. Research advance in rapid detection of foodborne Staphylococcus aureus

    OpenAIRE

    Xihong Zhao; Caijiao Wei; Junliang Zhong; Shiwei Jin

    2016-01-01

    Staphylococcus aureus is a gram-positive, coccus-shaped facultative anaerobe and a member of the Staphylococcaceae family. In recent years, alimentary toxicosis caused by S. aureus is a very serious problem worldwide, which constitutes a great threat to public health. In this review, we tried to summarize the conventional methods and newly developed rapid detection techniques of S. aureus (traditional detection method, biochemical detection, immunology method, molecular biology, and biosensor...

  7. From SRAFAP to SISAK - rapid chemical separations in nuclear research

    International Nuclear Information System (INIS)

    Herrmann, G.

    1988-10-01

    The author gives an overview of rapid radiochemical separations, starting from the early experiments done by Rutherford up to the very sophisticated recoil fragment separations by fast on-line methods as an attempt to produce superheavy elements. Main emphasis is given to developments during the last decades and the extensive work performed by collaborators of the Nuclear Chemistry Institute at the University of Mainz. (RB)

  8. Research and development

    Energy Technology Data Exchange (ETDEWEB)

    Harlow, Jr, J G

    1977-09-01

    The need for increased research and development programs to provide technological advances to meet future energy demands, particularly electric power demands, is discussed. It is concluded that the future energy needs of the world can only be supplied through technological improvements. The cost of these technological improvements can be minimized by cooperative, unified research and development programs. The financial support of the energy industry, the equipment manufacturing industry and the consumer will be required to finance these vital developments. The energy problems of the world can be solved by an adequately financed unified R and D effort. The U.S. must assume a major role of leadership in this world-wide effort. (LCL)

  9. Developing and validating rapid assessment instruments

    CERN Document Server

    Abell, Neil; Kamata, Akihito

    2009-01-01

    This book provides an overview of scale and test development. From conceptualization through design, data collection, analysis, and interpretation, critical concerns are identified and grounded in the increasingly sophisticated psychometric literature. Measurement within the health, social, and behavioral sciences is addressed, and technical and practical guidance is provided. Acknowledging the increasingly sophisticated contributions in social work, psychology, education, nursing, and medicine, the book balances condensation of complex conceptual challenges with focused recommendations for conceiving, planning, and implementing psychometric study. Primary points are carefully referenced and consistently illustrated to illuminate complicated or abstract principles. Basics of construct conceptualization and establishing evidence of validity are complimented with introductions to concept mapping and cross-cultural translation. In-depth discussion of cutting edge topics like bias and invariance in item responses...

  10. Hydropower research and development

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    This report is a compilation of information on hydropower research and development (R and D) activities of the Federal government and hydropower industry. The report includes descriptions of on-going and planned R and D activities, 1996 funding, and anticipated future funding. Summary information on R and D projects and funding is classified into eight categories: fish passage, behavior, and response; turbine-related; monitoring tool development; hydrology; water quality; dam safety; operations and maintenance; and water resources management. Several issues in hydropower R and D are briefly discussed: duplication; priorities; coordination; technical/peer review; and technology transfer/commercialization. Project information sheets from contributors are included as an appendix.

  11. Photonics Research and Development

    Energy Technology Data Exchange (ETDEWEB)

    Dickson, Elizabeth [UNLV Research Foundation, Las Vegas, NV (United States)

    2010-01-15

    During the period August 2005 through October 2009, the UNLV Research Foundation (UNLVRF), a non-profit affiliate of the University of Nevada, Las Vegas (UNLV), in collaboration with UNLV's Colleges of Science and Engineering; Boston University (BU); Oak Ridge National Laboratory (ORNL); and Sunlight Direct, LLC, has managed and conducted a diverse and comprehensive research and development program focused on light-emitting diode (LED) technologies that provide significantly improved characteristics for lighting and display applications. This final technical report provides detailed information on the nature of the tasks, the results of the research, and the deliverables. It is estimated that about five percent of the energy used in the nation is for lighting homes, buildings and streets, accounting for some 25 percent of the average home's electric bill. However, the figure is significantly higher for the commercial sector. About 60 percent of the electricity for businesses is for lighting. Thus replacement of current lighting with solid-state lighting technology has the potential to significantly reduce this nation's energy consumption by some estimates, possibly as high as 20%. The primary objective of this multi-year R&D project has been to develop and advance lighting technologies to improve national energy conversion efficiencies; reduce heat load; and significantly lower the cost of conventional lighting technologies. The UNLVRF and its partners have specifically focused these talents on (1) improving LED technologies; (2) optimizing hybrid solar lighting, a technology which potentially offers the benefits of blending natural with artificial lighting systems, thus improving energy efficiency; and (3) building a comprehensive academic infrastructure within UNLV which concentrates on photonics R&D. Task researchers have reported impressive progress in (1) the development of quantum dot laser emitting diodes (QDLEDs) which will ultimately improve

  12. Research advance in rapid detection of foodborne Staphylococcus aureus

    Directory of Open Access Journals (Sweden)

    Xihong Zhao

    2016-09-01

    Full Text Available Staphylococcus aureus is a gram-positive, coccus-shaped facultative anaerobe and a member of the Staphylococcaceae family. In recent years, alimentary toxicosis caused by S. aureus is a very serious problem worldwide, which constitutes a great threat to public health. In this review, we tried to summarize the conventional methods and newly developed rapid detection techniques of S. aureus (traditional detection method, biochemical detection, immunology method, molecular biology, and biosensor method for their principles, advantages, disadvantages, and applications. Furthermore, the future perspectives of S. aureus detection methods were forecasted at last.

  13. Development of Nylon Based FDM Filament for Rapid Tooling Application

    Science.gov (United States)

    Singh, R.; Singh, S.

    2014-04-01

    There has been critical need for development of cost effective nylon based wire to be used as feed stock filament for fused deposition modelling (FDM) machine. But hitherto, very less work has been reported for development of alternate solution of acrylonitrile butadiene styrene (ABS) based wire which is presently used in most of FDM machines. The present research work is focused on development of nylon based wire as an alternative of ABS wire (which is to be used as feedstock filament on FDM) without changing any hardware or software of machine. For the present study aluminium oxide (Al2O3) as additive in different proportion has been used with nylon fibre. Single screw extruder was used for wire preparation and wire thus produced was tested on FDM. Mechanical properties i.e. tensile strength and percentage elongation of finally developed wire have been optimized by Taguchi L9 technique. The work represented major development in reducing cost and time in rapid tooling applications.

  14. Ecotribology research developments

    CERN Document Server

    2016-01-01

    This book presents resent research advances in the area of eco-triobology. In the last years, eco-tribology or environmentally friendly tribology has gained increasing importance in sustainable engineering. Environmentally acceptable tribological practices save resources by optimizing product usage and reducing energy. This book covers current developments in all areas covered by the term eco-tribology, including biomimetics surfaces, control of friction and wear, environmental aspects of lubrication and surface modification techniques as well as tribological aspects of green applications, such wind-power turbines or solar panels.

  15. Research and development experience

    International Nuclear Information System (INIS)

    Slater, J.B.

    1980-06-01

    In the early 1950s, Atomic Energy of Canada Limited (AECL), in collaboration with Canadian industry and the power utilities, started on the task of developing and establishing the CANDU power reactor system and the necessary industrial infrastructure. While international activity provided a useful background and information to support Canadian activities, there were several unique features of the CANDU reactor which demanded specific programs of research and development work with a physics orientation. The four major areas were basic reactor physics, reactor control, heavy water and tritium monitoring and instruments and, finally, the potential of alternative fuel cycles. These four topics are discussed with the objective of providing an overview of what has been accomplished and what remains to be done. (auth)

  16. Technology research and development

    International Nuclear Information System (INIS)

    Haas, G.M.; Abdov, M.A.; Baker, C.C.; Beuligmann, R.F.

    1985-01-01

    The U.S. Dept. of Energy discusses the new program plan, the parameters of which are a broad scientific and technology knowledge base, an attractive plasma configuration to be determined, and other issues concerning uncertainty as to what constitutes attractive fusion options to be determined in the future, and increased collaboration. Tables show changing directions in magnetic fusion energy, two examples of boundary condition impacts on long-term technology development, and priority classes of the latter. The Argonne National Laboratory comments on the relationship between science, technology and the engineering aspects of the fusion program. UCLA remarks on the role of fusion technology in the fusion program plan, particularly on results from the recent studies of FINESSE. General Dynamics offers commentary on the issues of a reduced budget, and new emphasis on science which creates an image of the program. A table illustrates technology research and development in the program plan from an industrial perspective

  17. Cooperation in research and development

    International Nuclear Information System (INIS)

    Ramanna, R.

    1977-01-01

    In planning scientific programs for rapid and extensive peaceful applications of atomic energy in any developing country, it is not fully realized that one of the most important inputs is a strong research and development (R and D) base with a well-oriented training program. The paper discusses the various ways in which R and D is required to assist in both indigenous and turnkey projects. The R and D organization should be broad based; i.e., it should have physicists, chemists (particularly specialists in water chemistry), health physicists, and engineers (particularly metallurgists for materials development, study of corrosion problems, etc.). The role of electronic engineers is also very significant from the viewpoint of designing reactor control systems. Another important advantage of having an R and D program is its general technological fallout, which aids the entire industrial structure of the country. The concept of regional cooperation is very important, particularly for atomic energy programs in developing countries that have similar conditions and levels of technological skills. This cooperation can be bilateral or multilateral under the auspices of the International Atomic Energy Agency. Scientists from several countries have been trained in our Center, and we also had a very successful India-Philippines-Agency Project in which scientists from many countries in the region participated in cooperative research programs

  18. Research tools | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Through training materials and guides, we aim to build skills and knowledge to enhance the quality of development research. We also offer free access to our database of funded research projects, known as IDRIS+, and our digital library. Our research tools include. Guide to research databases at IDRC: How to access and ...

  19. Changing Research Practices and Research Infrastructure Development

    Science.gov (United States)

    Houghton, John W.

    2005-01-01

    This paper examines changing research practices in the digital environment and draws out implications for the development of research infrastructure. Reviews of the literature, quantitative indicators of research activities and our own field research in Australia suggest that there is a new mode of knowledge production emerging, changing research…

  20. Polygenic Risk, Rapid Childhood Growth, and the Development of Obesity

    Science.gov (United States)

    Belsky, Daniel W.; Moffitt, Terrie E.; Houts, Renate; Bennett, Gary G.; Biddle, Andrea K.; Blumenthal, James A.; Evans, James P.; Harrington, HonaLee; Sugden, Karen; Williams, Benjamin; Poulton, Richie; Caspi, Avshalom

    2012-01-01

    Objective To test how genomic loci identified in genome-wide association studies influence the development of obesity. Design A 38-year prospective longitudinal study of a representative birth cohort. Setting The Dunedin Multidisciplinary Health and Development Study, Dunedin, New Zealand. Participants One thousand thirty-seven male and female study members. Main Exposures We assessed genetic risk with a multilocus genetic risk score. The genetic risk score was composed of single-nucleotide polymorphisms identified in genome-wide association studies of obesity-related phenotypes. We assessed family history from parent body mass index data collected when study members were 11 years of age. Main Outcome Measures Body mass index growth curves, developmental phenotypes of obesity, and adult obesity outcomes were defined from anthropometric assessments at birth and at 12 subsequent in-person interviews through 38 years of age. Results Individuals with higher genetic risk scores were more likely to be chronically obese in adulthood. Genetic risk first manifested as rapid growth during early childhood. Genetic risk was unrelated to birth weight. After birth, children at higher genetic risk gained weight more rapidly and reached adiposity rebound earlier and at a higher body mass index. In turn, these developmental phenotypes predicted adult obesity, mediating about half the genetic effect on adult obesity risk. Genetic associations with growth and obesity risk were independent of family history, indicating that the genetic risk score could provide novel information to clinicians. Conclusions Genetic variation linked with obesity risk operates, in part, through accelerating growth in the early childhood years after birth. Etiological research and prevention strategies should target early childhood to address the obesity epidemic. PMID:22665028

  1. Eltron Research & Development

    Energy Technology Data Exchange (ETDEWEB)

    Evenson, Carl; Mackay, Richard; Faull, John

    2014-03-01

    This topical report covers technical work conducted under contract DE-FC26-05NT42469 between FY06 Q1 through FY14 Q2. The project evolved through several budget periods, budget revisions and continuation applications. This report covers work performed under the “base” program. In 2010 ARRA funding was added to the project. A separate report covering the ARRA portion of the project was submitted to DOE. The original project was focused on research and development for scale-up of hydrogen separation membrane for a FutureGen type power plant. The work included membrane testing and evaluation of metal alloy flat plates vs. tubes and metal membranes vs. cermet membranes. In addition, economic analysis and process modeling was performed. The original project team included CoorsTek, NORAM, and Praxair. In FY10Q2 a continuation application was filed for conducting a scale-up test at Eastman Chemical. In this part of the project a Subscale Engineering Prototype (SEP) membrane skid was designed, fabricated, and operated on a gasified coal slip-stream on Eastman’s site in Kingsport, TN. Following operation, the project was reorganized and a second continuation application with a new statement of work was initiated in FY12Q1. Finally, based on DOE’s decision not to proceed with a Process Development Unit (PDU) field test, a third continuation application and statement of work was initiated in FY13Q1 to close out the project.

  2. Understanding of research, genetics and genetic research in a rapid ethical assessment in north west Cameroon.

    Science.gov (United States)

    Kengne-Ouafo, Jonas A; Millard, James D; Nji, Theobald M; Tantoh, William F; Nyoh, Doris N; Tendongfor, Nicholas; Enyong, Peter A; Newport, Melanie J; Davey, Gail; Wanji, Samuel

    2016-05-01

    There is limited assessment of whether research participants in low-income settings are afforded a full understanding of the meaning of medical research. There may also be particular issues with the understanding of genetic research. We used a rapid ethical assessment methodology to explore perceptions surrounding the meaning of research, genetics and genetic research in north west Cameroon. Eleven focus group discussions (including 107 adults) and 72 in-depth interviews were conducted with various stakeholders in two health districts in north west Cameroon between February and April 2012. Most participants appreciated the role of research in generating knowledge and identified a difference between research and healthcare but gave varied explanations as to this difference. Most participants' understanding of genetics was limited to concepts of hereditary, with potential benefits limited to the level of the individual or family. Explanations based on supernatural beliefs were identified as a special issue but participants tended not to identify any other special risks with genetic research. We demonstrated a variable level of understanding of research, genetics and genetic research, with implications for those carrying out genetic research in this and other low resource settings. Our study highlights the utility of rapid ethical assessment prior to complex or sensitive research. © The Author 2015. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.

  3. Development of a Decision Aid for Cardiopulmonary Resuscitation Involving Intensive Care Unit Patients' and Health Professionals' Participation Using User-Centered Design and a Wiki Platform for Rapid Prototyping: A Research Protocol

    Science.gov (United States)

    Heyland, Daren Keith; Ebell, Mark H; Dupuis, Audrey; Lavoie-Bérard, Carole-Anne; Légaré, France; Archambault, Patrick Michel

    2016-01-01

    attending intensivists and alert and oriented patients discussing goals of care concerning CPR to understand how a patient DA could support this decision. We will also conduct individual interviews with the 5 intensivists to identify their needs concerning the implementation of a DA. In the second phase of the study, we will build a first prototype based on the needs identified in Phase I. We will start by translating an existing DA entitled “Cardiopulmonary resuscitation: a decision aid for patients and their families.” We will then adapt this tool to the needs we identified in Phase I and archive this first prototype in a wiki. Building on the wiki’s programming architecture, we intend to integrate the Good Outcome Following Attempted Resuscitation risk calculator into our DA to determine personal risks and benefits of CPR for each patient. We will then present the first prototype to 5 new patient-intensivist dyads. Feedback about content and visual presentation will be collected from the intensivists through short interviews while longer interviews will be conducted with patients and their family members to inform the visual design and content of the next prototype. After each rapid prototyping cycle, 2 researchers will perform qualitative content analysis of data collected through interviews and direct observations. We will attempt to solve all content and visual design issues identified before moving to the next round of prototyping. In all, we will conduct 3 prototyping cycles with a total of 15 patient-intensivist dyads. Results We expect to develop a multimedia wiki-based DA to support goals of care discussions about CPR adapted to the local needs of patients, their family members, and intensivists and tailorable to individual patient risk factors. The final version of the DA as well as the development process will be housed in an open-access wiki and free to be adapted and used in other contexts. Conclusions This study will shed new light on the development

  4. International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... development. Learn moreArtificial intelligence and human development ... New initiative will match climate knowledge to developing country needs. Aminata Camara ... Shadow Libraries: Access to Knowledge in Global Higher Education.

  5. Methods for Rapid Screening in Woody Plant Herbicide Development

    Directory of Open Access Journals (Sweden)

    William Stanley

    2014-07-01

    Full Text Available Methods for woody plant herbicide screening were assayed with the goal of reducing resources and time required to conduct preliminary screenings for new products. Rapid screening methods tested included greenhouse seedling screening, germinal screening, and seed screening. Triclopyr and eight experimental herbicides from Dow AgroSciences (DAS 313, 402, 534, 548, 602, 729, 779, and 896 were tested on black locust, loblolly pine, red maple, sweetgum, and water oak. Screening results detected differences in herbicide and species in all experiments in much less time (days to weeks than traditional field screenings and consumed significantly less resources (<500 mg acid equivalent per herbicide per screening. Using regression analysis, various rapid screening methods were linked into a system capable of rapidly and inexpensively assessing herbicide efficacy and spectrum of activity. Implementation of such a system could streamline early-stage herbicide development leading to field trials, potentially freeing resources for use in development of beneficial new herbicide products.

  6. Economic Growth of a Rapidly Developing Economy: Theoretical Formulation

    Directory of Open Access Journals (Sweden)

    Oleg Sergeyevich Sukharev

    2016-06-01

    Full Text Available The subject matter of the article is the description of economic growth. Modern economy is characterized by a high rate of changes. These changes are the limiting parameters of modern development, which requires a modification of the basic models of growth, the substantiation of the expediency and necessity of a rapid development strategy. In a simple mathematical form, the statement of the problem of economic growth in the “green economy” is examined, in which the costs of environmental measures are not considered a priori as hampering economic development (as it is common for a number of modern neoclassical and neo-Keynesian growth models. The methodological basis of the article are the econometric approach and modelling method. The article has a theoretical character. The main hypothesis supposes that the rapid development strategy cannot make an adequate development strategy under certain conditions, but may be acceptable in other its specific conditions. In this sense, the important growth conditions are the availability of resources, the effectiveness of institutions and the current economic structure, the technological effectiveness of economy, as well as the conditions of technological development (“green economy” and the path of such development. In the article, on the theoretical level of analysis, the substantiation of the adequacy of the rapid development strategy for an economic system is given, whose goal is to achieve the standard of living of the countryleader. Based on the assumptions introduced, the period for which the rapid development strategy might be implemented and the economic lag of the country might be reduced from the country-leader is determined. The conditions that ensure the impact of innovations on the rate of economic development are summarized. The introduced range of dependencies and relations can be useful for the elaboration of the theory of innovation development and for the formation of a new

  7. Development of flexural vibration inspection techniques to rapidly assess the structural health of rural bridge systems

    Science.gov (United States)

    Brian K. Brashaw; Robert Vatalaro; Xiping Wang; Kevin Sarvela; James P. Wacker

    2008-01-01

    Approximately 4,000 vehicle bridges in the State of Minnesota contain structural timber members. Recent research at the University of Minnesota Duluth Natural Resources Research Institute (UMD NRRI) has been conducted on vibration testing of timber bridges as a means of developing rapid in-place testing techniques for assessing the structural health of bridges. The...

  8. Rapid development of paper-based fluidic diagnostic devices

    CSIR Research Space (South Africa)

    Smith, S

    2014-11-01

    Full Text Available We present a method for rapid and low-cost development of microfluidic diagnostic devices using paper-based techniques. Specifically, the implementation of fluidic flow paths and electronics on paper are demonstrated, with the goal of producing...

  9. Research Librarian | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Job Summary The Research Librarian is a key member of a team responsible for the delivery of comprehensive research information services which contribute strategic value to the work of clients. Intermediated search services at the expert level, the development and delivery of orientations, training/coaching, ...

  10. Modeling of subglacial hydrological development following rapid supraglacial lake drainage

    OpenAIRE

    Dow, C F; Kulessa, B; Rutt, I C; Tsai, V C; Pimentel, S; Doyle, S H; van As, D; Lindb?ck, K; Pettersson, R; Jones, G A; Hubbard, A

    2015-01-01

    The rapid drainage of supraglacial lakes injects substantial volumes of water to the bed of the Greenland ice sheet over short timescales. The effect of these water pulses on the development of basal hydrological systems is largely unknown. To address this, we develop a lake drainage model incorporating both (1) a subglacial radial flux element driven by elastic hydraulic jacking and (2) downstream drainage through a linked channelized and distributed system. Here we present the model and exa...

  11. Development of rapid mixing fuel nozzle for premixed combustion

    International Nuclear Information System (INIS)

    Katsuki, Masashi; Chung, Jin Do; Kim, Jang Woo; Hwang, Seung Min; Kim, Seung Mo; Ahn, Chul Ju

    2009-01-01

    Combustion in high-preheat and low oxygen concentration atmosphere is one of the attractive measures to reduce nitric oxide emission as well as greenhouse gases from combustion devices, and it is expected to be a key technology for the industrial applications in heating devices and furnaces. Before proceeding to the practical applications, we need to elucidate combustion characteristics of non-premixed and premixed flames in high-preheat and low oxygen concentration conditions from scientific point of view. For the purpose, we have developed a special mixing nozzle to create a homogeneous mixture of fuel and air by rapid mixing, and applied this rapidmixing nozzle to a Bunsen-type burner to observe combustion characteristics of the rapid-mixture. As a result, the combustion of rapid-mixture exhibited the same flame structure and combustion characteristics as the perfectly prepared premixed flame, even though the mixing time of the rapid-mixing nozzle was extremely short as a few milliseconds. Therefore, the rapid-mixing nozzle in this paper can be used to create preheated premixed flames as far as the mixing time is shorter than the ignition delay time of the fuel

  12. Extending NASA Research Results to Benefit Society: Rapid Prototyping for Coastal Applications

    Science.gov (United States)

    Glorioso, Mark V.; Miller, Richard L.; Hall, Callie M.; McPherson, Terry R.

    2006-01-01

    The mission of the NASA Applied Sciences Program is to expand and accelerate the use of NASA research results to benefit society in 12 application areas of national priority. ONe of the program's major challenges is to perform a quick, efficient, and detailed review (i.e., prototyping) of the large number of combinations of NASA observations and results from Earth system models that may be used by a wide range of decision support tools. A Rapid Prototyping Capacity (RPC) is being developed to accelerate the use of NASA research results. Here, we present the conceptual framework of the Rapid Prototyping Capacity within the context of quickly assessing the efficacy of NASA research results and technologies to support the Coastal Management application. An initial RPC project designed to quickly evaluate the utility of moderate-resolution MODIS products for calibrating/validating coastal sediment transport models is also presented.

  13. Education in Management of Data Created by New Technologies for Rapid Product Development in SMEs

    Science.gov (United States)

    Shaw, A.; Aitchison, D.

    2003-01-01

    This paper presents outcomes from a research programme aimed at developing new tools and methodologies to assist small and medium-sized enterprises (SMEs) in rapid product development (RPD). The authors suggest that current education strategies for the teaching of RPD tools and methodologies may be of limited value unless those strategies also…

  14. Rapid Deployment of a RESTful Service for Oceanographic Research Cruises

    Science.gov (United States)

    Fu, Linyun; Arko, Robert; Leadbetter, Adam

    2014-05-01

    The Ocean Data Interoperability Platform (ODIP) seeks to increase data sharing across scientific domains and international boundaries, by providing a forum to harmonize diverse regional data systems. ODIP participants from the US include the Rolling Deck to Repository (R2R) program, whose mission is to capture, catalog, and describe the underway/environmental sensor data from US oceanographic research vessels and submit the data to public long-term archives. R2R publishes information online as Linked Open Data, making it widely available using Semantic Web standards. Each vessel, sensor, cruise, dataset, person, organization, funding award, log, report, etc, has a Uniform Resource Identifier (URI). Complex queries that federate results from other data providers are supported, using the SPARQL query language. To facilitate interoperability, R2R uses controlled vocabularies developed collaboratively by the science community (eg. SeaDataNet device categories) and published online by the NERC Vocabulary Server (NVS). In response to user feedback, we are developing a standard programming interface (API) and Web portal for R2R's Linked Open Data. The API provides a set of simple REST-type URLs that are translated on-the-fly into SPARQL queries, and supports common output formats (eg. JSON). We will demonstrate an implementation based on the Epimorphics Linked Data API (ELDA) open-source Java package. Our experience shows that constructing a simple portal with limited schema elements in this way can significantly reduce development time and maintenance complexity.

  15. International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Ann Gregory

    further development of scientific agriculture and technology. Already, however ..... sent, starting in the north, to Galilee and the regions adjoining, Lebanon and Syria, and working my ... the water, grow crops, and flocks of sheep and goats.” He says ... I served in 30 or 40 different countries throughout Asia and Africa, South.

  16. Offshore wind development research.

    Science.gov (United States)

    2014-04-01

    Offshore wind (OSW) development is a new undertaking in the US. This project is a response to : New Jerseys 2011 Energy Master Plan that envisions procuring 22.5% of the states power : originating from renewable sources by 2021. The Offshore Wi...

  17. Rapid Development, Build-Out Ratio and Subsequent Neighborhood Turnover

    Directory of Open Access Journals (Sweden)

    George O. Rogers

    2018-04-01

    Full Text Available Neighborhood development is primarily comprised of structural elements that include design elements, nearby amenities and ecological attributes. This paper assumes that the process of development itself also influences the character of the neighborhood—specifically, that the rate of development and build-out ratio influences neighborhood turnover. While the structural components clearly set a framework for development, the process of development expresses the character of the neighborhood in subtle messages conveyed through the market. Neighborhoods in the rapidly growing university town of College Station, Texas are analyzed in terms of neighborhood design, nearby amenities and landscape ecology components. Residential property records are used to characterize each neighborhood in terms of the rate of development and current build-out ratio. The multivariate analysis indicates that the development rate increases subsequent neighborhood turnover rates while the build-out ratio decreases it.

  18. Faster Growth of Road Transportation CO2 Emissions in Asia Pacific Economies: Exploring Differences in Trends of the Rapidly Developing and Developed Worlds

    Science.gov (United States)

    Marcotullio, Peter J.

    2006-01-01

    Researchers have identified how in some rapidly developing countries, road and aviation transportation CO2 emissions are rising faster (over time) when compared to the experiences of the USA at similar levels of economic development. While suggestive of how experiences of the rapidly developing Asia are different from those of the developed world…

  19. Mesothelioma as a rapidly developing Giant Abdominal Cyst

    Directory of Open Access Journals (Sweden)

    Vyas Dinesh

    2012-12-01

    Full Text Available Abstract The benign cystic mesothelioma of the peritoneum is a rare lesion and is known for local recurrence. This is first case report of a rapidly developing massive abdominal tumor with histological finding of benign cystic mesothelioma (BCM. We describe a BCM arising in the retroperitoneal tis[sue on the right side, lifting ascending colon and cecum to the left side of abdomen. Patient was an active 58-year-old man who noticed a rapid abdominal swelling within a two month time period with a weight gain of 40 pounds. Patient had no risk factors including occupational (asbestos, cadmium, family history, social (alcohol, smoking or history of trauma. We will discuss the clinical, radiologic, intra-operative, immunohistochemical, pathologic findings, and imaging six months after surgery. Patient has no recurrence and no weight gain on follow up visits and imaging.

  20. Rapid qualitative research methods during complex health emergencies: A systematic review of the literature.

    Science.gov (United States)

    Johnson, Ginger A; Vindrola-Padros, Cecilia

    2017-09-01

    The 2013-2016 Ebola outbreak in West Africa highlighted both the successes and limitations of social science contributions to emergency response operations. An important limitation was the rapid and effective communication of study findings. A systematic review was carried out to explore how rapid qualitative methods have been used during global heath emergencies to understand which methods are commonly used, how they are applied, and the difficulties faced by social science researchers in the field. We also asses their value and benefit for health emergencies. The review findings are used to propose recommendations for qualitative research in this context. Peer-reviewed articles and grey literature were identified through six online databases. An initial search was carried out in July 2016 and updated in February 2017. The PRISMA checklist was used to guide the reporting of methods and findings. The articles were assessed for quality using the MMAT and AACODS checklist. From an initial search yielding 1444 articles, 22 articles met the criteria for inclusion. Thirteen of the articles were qualitative studies and nine used a mixed-methods design. The purpose of the rapid studies included: the identification of causes of the outbreak, and assessment of infrastructure, control strategies, health needs and health facility use. The studies varied in duration (from 4 days to 1 month). The main limitations identified by the authors were: the low quality of the collected data, small sample sizes, and little time for cross-checking facts with other data sources to reduce bias. Rapid qualitative methods were seen as beneficial in highlighting context-specific issues that need to be addressed locally, population-level behaviors influencing health service use, and organizational challenges in response planning and implementation. Recommendations for carrying out rapid qualitative research in this context included the early designation of community leaders as a point of

  1. Development Of A Data Assimilation Capability For RAPID

    Science.gov (United States)

    Emery, C. M.; David, C. H.; Turmon, M.; Hobbs, J.; Allen, G. H.; Famiglietti, J. S.

    2017-12-01

    The global decline of in situ observations associated with the increasing ability to monitor surface water from space motivates the creation of data assimilation algorithms that merge computer models and space-based observations to produce consistent estimates of terrestrial hydrology that fill the spatiotemporal gaps in observations. RAPID is a routing model based on the Muskingum method that is capable of estimating river streamflow over large scales with a relatively short computing time. This model only requires limited inputs: a reach-based river network, and lateral surface and subsurface flow into the rivers. The relatively simple model physics imply that RAPID simulations could be significantly improved by including a data assimilation capability. Here we present the early developments of such data assimilation approach into RAPID. Given the linear and matrix-based structure of the model, we chose to apply a direct Kalman filter, hence allowing for the preservation of high computational speed. We correct the simulated streamflows by assimilating streamflow observations and our early results demonstrate the feasibility of the approach. Additionally, the use of in situ gauges at continental scales motivates the application of our new data assimilation scheme to altimetry measurements from existing (e.g. EnviSat, Jason 2) and upcoming satellite missions (e.g. SWOT), and ultimately apply the scheme globally.

  2. Translational Research and Youth Development

    Science.gov (United States)

    Hamilton, Stephen F.

    2015-01-01

    Borrowing the term "translational research" (TR) from medicine, along with some of the ideas and practices that define it, holds promise as a way of linking research more closely to the practice of youth development. However, doing so entails substantial adaptation. TR is more than a new name for applied research. It comprehends the…

  3. Verification and Validation in a Rapid Software Development Process

    Science.gov (United States)

    Callahan, John R.; Easterbrook, Steve M.

    1997-01-01

    The high cost of software production is driving development organizations to adopt more automated design and analysis methods such as rapid prototyping, computer-aided software engineering (CASE) tools, and high-level code generators. Even developers of safety-critical software system have adopted many of these new methods while striving to achieve high levels Of quality and reliability. While these new methods may enhance productivity and quality in many cases, we examine some of the risks involved in the use of new methods in safety-critical contexts. We examine a case study involving the use of a CASE tool that automatically generates code from high-level system designs. We show that while high-level testing on the system structure is highly desirable, significant risks exist in the automatically generated code and in re-validating releases of the generated code after subsequent design changes. We identify these risks and suggest process improvements that retain the advantages of rapid, automated development methods within the quality and reliability contexts of safety-critical projects.

  4. Ethiopian Journal of Development Research

    African Journals Online (AJOL)

    Log in or Register to get access to full text downloads. ... The Ethiopian Journal of Development Research (EJDR) is a bi-annual journal devoted to ... It is devoted to the multi-disciplinary study of development problems of Ethiopia in particular ... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

  5. Provincial resource development research policy

    Energy Technology Data Exchange (ETDEWEB)

    Flock, D L

    1976-01-01

    In Alberta, there is an abundance of oil, natural gas, and coal. But only a small portion of the Alberta oil sands and coal resources are commercially accessible to surface-mining techniques. It is quite apparent that some in-situ technological breakthrough will be required, which will mean a concerted research effort at the provincial level. It is the purpose of this paper to present certain concepts and recommendations for a coordinated provincial resource development research policy for the Province of Alberta. Research as discussed in this paper covers basic and applied research and development. (MCW)

  6. Research on parafoil stability using a rapid estimate model

    Directory of Open Access Journals (Sweden)

    Hua YANG

    2017-10-01

    Full Text Available With the consideration of rotation between canopy and payload of parafoil system, a four-degree-of-freedom (4-DOF longitudinal static model was used to solve parafoil state variables in straight steady flight. The aerodynamic solution of parafoil system was a combination of vortex lattice method (VLM and engineering estimation method. Based on small disturbance assumption, a 6-DOF linear model that considers canopy additional mass was established with benchmark state calculated by 4-DOF static model. Modal analysis of a dynamic model was used to calculate the stability parameters. This method, which is based on a small disturbance linear model and modal analysis, is high-efficiency to the study of parafoil stability. It is well suited for rapid stability analysis in the preliminary stage of parafoil design. Using this method, this paper shows that longitudinal and lateral stability will both decrease when a steady climbing angle increases. This explains the wavy track of the parafoil observed during climbing.

  7. Research and development toward Monju

    International Nuclear Information System (INIS)

    Nakamoto, Koichiro; Ikegami, Tetsuo; Sikakura, Sakae; Iwata, Koji; Yamaguchi, Katsuhisa; Kodaira, Kiyoshi

    1994-01-01

    Power Reactor and Nuclear Fuel Development Corporation aimed at the development of the experimental FBR ''Joyo'' and the prototype FBR ''Monju'', and has promoted the research and development of respective fields of reactor physics, shielding, fuel, safety, sodium technology, machinery and equipment, structural materials, measurement and control by cooperating with Japan Atomic Energy Research Institute, universities, national and public research institutes, electric power and manufacturing companies. Also the promotion of the development by international cooperation has been carried out positively. As for the core and fuel, the Japan-UK joint research ''MOZART project'' for the increase of reactor power output and the heightening of fuel burnup, and the test of MOX fuel, as for machinery, equipment and structure, the rationalization of structural design, the development of steam generator, the test with sodium testing facility, and as for safety, the test on the events related to the core, decay heat removing system and containment system were carried out. (K.I.)

  8. Development of a rapid, simple assay of plasma total carotenoids

    Science.gov (United States)

    2012-01-01

    Background Plasma total carotenoids can be used as an indicator of risk of chronic disease. Laboratory analysis of individual carotenoids by high performance liquid chromatography (HPLC) is time consuming, expensive, and not amenable to use beyond a research laboratory. The aim of this research is to establish a rapid, simple, and inexpensive spectrophotometric assay of plasma total carotenoids that has a very strong correlation with HPLC carotenoid profile analysis. Results Plasma total carotenoids from 29 volunteers ranged in concentration from 1.2 to 7.4 μM, as analyzed by HPLC. A linear correlation was found between the absorbance at 448 nm of an alcohol / heptane extract of the plasma and plasma total carotenoids analyzed by HPLC, with a Pearson correlation coefficient of 0.989. The average coefficient of variation for the spectrophotometric assay was 6.5% for the plasma samples. The limit of detection was about 0.3 μM and was linear up to about 34 μM without dilution. Correlations between the integrals of the absorption spectra in the range of carotenoid absorption and total plasma carotenoid concentration gave similar results to the absorbance correlation. Spectrophotometric assay results also agreed with the calculated expected absorbance based on published extinction coefficients for the individual carotenoids, with a Pearson correlation coefficient of 0.988. Conclusion The spectrophotometric assay of total carotenoids strongly correlated with HPLC analysis of carotenoids of the same plasma samples and expected absorbance values based on extinction coefficients. This rapid, simple, inexpensive assay, when coupled with the carotenoid health index, may be useful for nutrition intervention studies, population cohort studies, and public health interventions. PMID:23006902

  9. Knowledge to Policy: Making the Most of Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    5 avr. 2009 ... A major contribution to an understudied, poorly understood, but critical aspect of development. — John Young, Director of Programmes, Research and Policy in Development Group (RAPID), Overseas Development Institute, London. Does research influence public policy and decision-making and, if so, ...

  10. Research and development of CRIEPI

    International Nuclear Information System (INIS)

    Akita, Shirabe

    2008-01-01

    Central Research Institute of Electric Power Industry (CRIEPI) reported its R and D of nuclear power technologies. The research results of light water reactor aging deterioration contain the estimation method of irradiation embrittlement of pressure vessel, stress corrosion cracking of piping and core internal structure, and pipe thinning. The backend project support researches include transpiration and storage of recycle fuel, the high-level radioactive waste disposal and low-level radioactive waste disposal. Safety of concrete cask storage was confirmed by the falling test, SCC test and vibration test. The researches for the next generation nuclear technologies have developed the pyrochemical reprocessing process for the metal fuel and oxide fuel, and development of metal fuel with U, Pu and Zr. Assist management of development of fast reactor is proceeding. One of researches of radiation safety is on low dose X-ray bystander effect on the diabetes mellitus of model mouse. (S.Y.)

  11. Microstructural Development in Al-Si Powder During Rapid Solidification

    Energy Technology Data Exchange (ETDEWEB)

    Genau, Amber Lynn [Iowa State Univ., Ames, IA (United States)

    2004-01-01

    Powder metallurgy has become an increasingly important form of metal processing because of its ability to produce materials with superior mechanical properties. These properties are due in part to the unique and often desirable microstructures which arise as a result of the extreme levels of undercooling achieved, especially in the finest size powder, and the subsequent rapid solidification which occurs. A better understanding of the fundamental processes of nucleation and growth is required to further exploit the potential of rapid solidification processing. Aluminum-silicon, an alloy of significant industrial importance, was chosen as a model for simple eutectic systems displaying an unfaceted/faceted interface and skewed coupled eutectic growth zone, Al-Si powder produced by high pressure gas atomization was studied to determine the relationship between microstructure and alloy composition as a function of powder size and atomization gas. Critical experimental measurements of hypereutectic (Si-rich) compositions were used to determine undercooling and interface velocity, based on the theoretical models which are available. Solidification conditions were analyzed as a function of particle diameter and distance from nucleation site. A revised microstructural map is proposed which allows the prediction of particle morphology based on temperature and composition. It is hoped that this work, by providing enhanced understanding of the processes which govern the development of the solidification morphology of gas atomized powder, will eventually allow for better control of processing conditions so that particle microstructures can be optimized for specific applications.

  12. Early Detection of Rapidly Developing Cumulus Area using HIMAWARI-8

    Science.gov (United States)

    Yamada, Y.; Kadosaki, G.

    2017-12-01

    In recent years, many disasters have been occured by influence of meteorological change in Japan. So, it becomes more important to inform rapid weather change caused by cumulus which brings concentrated heavy rain/hail, wind gust, lightning in a short period. These severe events should inclease in the future by global warming. Therefore we are developping the alert system for Rapidly Developing Cumulus Area (RDCA) detection using Japanese new satellite. At July 2015, Japan Meteorological Agency started operation of new geostationary meteorological satellite "Himawari-8". This satellite has optical imager named Advanced Himawari Imager (AHI). It can observe Japan area every 2.5 minutes. The frequently infrared image with high resolution (2km) is the key of our alert system. We took some special functions in the algorithm of this system. One of the points is cloud location which shifts to north from true location around Japan by viewing angle from the satellite above the equator. We moved clouds to the correct position using geometric correction method according to its height and latitude. This algorithm also follows a movement of cloud every 2.5 minutes during several observations. It derives the information about degree of the development of cumulus. The prototype system gives the alert before 30 to 60 minutes in advance to the first lightning in typical cumulus case. However, we understand that there are some difficult cases to alert. For example, winter low cloud over the Japan Sea which brings a winter lightning, and tornado (although it is not cumulus). Now, we are adjusting some parameters of the algorithm. In the near future, our algorithm will be used in weather information delivery service to the customer.

  13. Fiscal 2000 regional consortium research and development project - regional new technology creation research and development. Massive rapid identification of gene functions; 2000 nendo chiiki consortium kenkyu kaihatsu jigyo - chiiki shingijutsu soshutsu kenkyu kaihatsu seika hokokusho. Idenshi kino no tairyo jinsoku dotei ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Efforts are exerted to develop a system for massive and rapid identification of unknown genes through the utilization of techniques based on the unusual membrane fusion characteristics of HVJ (hemagglutinating virus of Japan), which enables the introduction of genes efficiently and uniformly into cultured cells and living organs (development into a kit). Activities are conducted in the three fields of (1) the development of a method for introducing genes using an HVJ envelop vector, (2) a survey of kit marketing and cold storage facilities in the selling and distribution of the kit, and (3) a comprehensive survey. In the field of (1), studies are conducted for the establishment of methods for HVJ envelop vector production and refining, the establishment of an optimized method for encapsulating genes into the HVJ envelop vector, and the introduction of genes into cultured central neurons using the HVJ envelop vector system. A refining method has been established, which comprises the inoculation of HVJ into eggs, 4-day culture, egg cutting, liquid sampling (chorioallantoic liquid), inactivation (addition of alkylating agent), filtration, enrichment (ultrafiltration), and an anion exchange chromatogram. (NEDO)

  14. Managing air quality in a rapidly developing nation: China

    Science.gov (United States)

    Fang, Ming; Chan, Chak K.; Yao, Xiaohong

    As the world gets ready to begin the second decade of the twenty-first century, global climate change has been recognized as a real threat to civilization as we know it. The rapid and successful economic growth of developing nations, particularly China and India, is contributing to climate change. The route to initial economic success in China followed that of the developed nations through the development of industries. Unfortunately, China's environmental protection efforts have not been the same as in developed countries because China is vastly different culturally, socially, economically and, especially, politically from developed nations. When China started to deal with environmental concerns in the late 1970s, it took advantage of the experiences of other countries in establishing environmental standards and regulations, but it did not have a model to follow when it came to implementing these standards and regulations because of the abovementioned differences. Economically, China is transitioning from an agricultural base into an industrial base; however, even now, 60% of the population remains farmers. China has been and still is heavily dependent upon coal for energy, resulting in serious atmospheric particulate pollution. While growing efforts have been expended on the environment, at this juncture of its economic development, China would be well served to revisit the traditional "develop first and clean up later" approach and to find a balance between development and protecting the environment. Against this backdrop, a reflective look of the effort to manage air quality from 1949-2008 (with an emphasis on the past 30 years) in China is presented in this paper. The environmental component of the 2008 Olympic Games is examined as a special example to illustrate the current measures being used to improve air quality in China.

  15. Rapid Development of Bespoke Unmanned Platforms for Atmospheric Science

    Science.gov (United States)

    Sobester, A.; Johnston, S. J.; Scanlan, J. P.; Hart, E. E.; O'Brien, N. S.

    2012-04-01

    The effective deployment of airborne atmospheric science instruments often hinges on the development cycle time of a suitable platform, one that is capable of delivering them to the desired altitude range for a specified amount of time, along a pre-determined trajectory. This could be driven by the need to respond rapidly to sudden, unexpected events (e.g., volcano eruptions, nuclear fallout, etc.) or simply to accommodate the iterative design and flight test cycle of the instrument developer. A shorter development cycle time would also afford us the ability to quickly adapt the hardware and control logic in response to unexpected results during an experimental campaign. We report on recent developments aimed at meeting this demand. As part of the Atmospheric Science Through Robotic Aircraft (ASTRA) initiative we have investigated the use of rapid prototyping technologies to this end, both on the 'airframe' of the platform itself and on the on-board systems. We show how fast multi-disciplinary design optimization techniques, coupled with computer-controlled additive manufacturing (3D printing) and laser cutting methods and electronic prototyping (using standard, modular, programmable building blocks) can lead to the delivery of a fully customized platform integrating a given instrument in a timescale of the order of ten days. Specific examples include the design and testing of a balloon-launched glider sensorcraft and a stratospheric balloon system. The 'vehicle' for the latter was built on a 3D printer using a copolymer thermoplastic material and fitted with a sacrificial protective 'cage' laser-cut from an open-cell foam. The data logging, tracking, sensor integration and communications services of the platform were constructed using the .net Gadgeteer open source hardware kit. The flight planning and eventual post-flight recovery of the system is enabled by a generic, stochastic trajectory simulation tool, also developed as part of the ASTRA initiative. This

  16. Rapid Response Risk Assessment in New Project Development

    Science.gov (United States)

    Graber, Robert R.

    2010-01-01

    A capability for rapidly performing quantitative risk assessments has been developed by JSC Safety and Mission Assurance for use on project design trade studies early in the project life cycle, i.e., concept development through preliminary design phases. A risk assessment tool set has been developed consisting of interactive and integrated software modules that allow a user/project designer to assess the impact of alternative design or programmatic options on the probability of mission success or other risk metrics. The risk and design trade space includes interactive options for selecting parameters and/or metrics for numerous design characteristics including component reliability characteristics, functional redundancy levels, item or system technology readiness levels, and mission event characteristics. This capability is intended for use on any project or system development with a defined mission, and an example project will used for demonstration and descriptive purposes, e.g., landing a robot on the moon. The effects of various alternative design considerations and their impact of these decisions on mission success (or failure) can be measured in real time on a personal computer. This capability provides a high degree of efficiency for quickly providing information in NASA s evolving risk-based decision environment

  17. Rapid application development using the Tcl/Tk language

    International Nuclear Information System (INIS)

    van Zeijts, J.

    1995-01-01

    During the last year, high level applications at CEBAF were written using the Tcl/Tk scripting language. This language is rapidly gaining in popularity, in part due to ease of constructing programs with X11 graphical user interfaces, and in part to ease of adding compiled user code for specialized purposes. Extensions to the language provide object oriented programming, which was used to develop a hierarchy of classes relevant for high level accelerator control. We describe basic language features, some 3rd party add-on packages, and local additions to the toolbox. Next we describe features of the accelerator object hierarchy, and finally describe applications written using this toolbox such as the ModelServer prototype, Slow Orbit and Energy Lock, the Linac Energy Management System, and other applications

  18. Rapid Application Development with OpenStudio: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Weaver, E.; Long, N.; Fleming, K.; Schott, M.; Benne, K.; Hale, E.

    2012-05-01

    This paper presents several case studies of rapidly implemented, audience-specific applications for whole building energy modeling and standards analysis. By tailoring each application to the audience and the task at hand, the required learning curve for new users was greatly reduced. Each case study used OpenStudio, the U.S. Department of Energy's middleware software development kit (SDK). OpenStudio provides an easy interface to the EnergyPlus whole building simulation engine, while extending its capability and providing higher-level functionality such as software interoperability, standards, analysis, and optimization. Each case study is unique in the technology employed to interface with OpenStudio as well as the methods used for user interaction and data presentation. Four case studies are presented.

  19. Cancer Research UK | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cancer Research UK. Cancer Research UK. https://www.cancerresearchuk.org/. The Economics of Tobacco Control Research Initiative. The Economics of Tobacco Control Research Initiative funds innovative fiscal policy research supporting tobacco control in low and middle-income countries. View more. The Economics ...

  20. Fundamental research in developing countries

    International Nuclear Information System (INIS)

    Moravesik, M.J.

    1964-01-01

    Technical assistance is today a widespread activity. Large numbers of persons with special qualifications in the applied sciences go to the developing countries to work on specific research and development projects, as do educationists on Fulbright or other programmes - usually to teach elementary or intermediate courses. But I believe that until now it has been rare for a person primarily interested in fundamental research to go to one of these countries to help build up advanced education and pure research work. Having recently returned from such an assignment, and having found it a most stimulating and enlightening experience, I feel moved to urge strongly upon others who may be in a position to do so that they should seek similar experience themselves. The first step is to show that advanced education and fundamental research are badly needed in the under-developed countries.

  1. Development research: The environmental challenge

    International Nuclear Information System (INIS)

    Winpenny, J.T.

    1991-01-01

    This book represents papers from a 1990 conference 'The environment, Development and Economic Research'. The focus of the book is the environmental and natural resource use problems, though economic development is a strong co-theme. Chapters cover the following topic areas: international issues; macroeconomic policies; natural resource degradation; urban problems; social dimensions; bio-diversity; energy; economic valuation

  2. Nuclear safeguards research and development

    Science.gov (United States)

    Henry, C. N.

    1981-11-01

    The status of a nuclear safeguard research and development program is presented. Topics include nondestructive assay technology development and applications, international safeguards, training courses, technology transfer, analytical chemistry methods for fissionable materials safeguards, the Department of Energy Computer Security Technical Center, and operational security.

  3. Fostering Collaborations towards Integrative Research Development

    Directory of Open Access Journals (Sweden)

    Leonie Valentine

    2013-05-01

    Full Text Available The complex problems associated with global change processes calls for close collaboration between science disciplines to create new, integrated knowledge. In the wake of global change processes, forests and other natural environments have been rapidly changing, highlighting the need for collaboration and integrative research development. Few tools are available to explore the potential for collaborations in research ventures that are just starting up. This study presents a useful approach for exploring and fostering collaborations between academics working in research teams and organizations comprising multiple science disciplines (i.e., multi-disciplinary. The research aim was to reveal potential barriers, common ground, and research strengths between academics working in a new centre focused on forest and climate change research. This aim was based on the premise that raising awareness and working with this acquired knowledge fosters collaborations and integrative research development. An email survey was deployed amongst the academics to obtain: (i their understanding of common themes (e.g., climate change, scale of investigation, woodland/forest health/decline; (ii descriptions of the spatial and temporal scales of their research; and (iii their approach and perceived contributions to climate change research. These data were analysed using a semi-quantitative content analysis approach. We found that the main potential barriers were likely to be related to differences in understanding of the common research themes, whilst similarities and disciplinary strengths provided critical elements to foster collaborations. These findings were presented and discussed amongst the centre academics to raise awareness and create a dialogue around these issues. This process resulted in the development of four additional research projects involving multiple disciplines. The approach used in this study provides a useful methodology of broader benefit to

  4. Rapid research and implementation priority setting for wound care uncertainties.

    Directory of Open Access Journals (Sweden)

    Trish A Gray

    Full Text Available People with complex wounds are more likely to be elderly, living with multimorbidity and wound related symptoms. A variety of products are available for managing complex wounds and a range of healthcare professionals are involved in wound care, yet there is a lack of good evidence to guide practice and services. These factors create uncertainty for those who deliver and those who manage wound care. Formal priority setting for research and implementation topics is needed to more accurately target the gaps in treatment and services. We solicited practitioner and manager uncertainties in wound care and held a priority setting workshop to facilitate a collaborative approach to prioritising wound care-related uncertainties.We recruited healthcare professionals who regularly cared for patients with complex wounds, were wound care specialists or managed wound care services. Participants submitted up to five wound care uncertainties in consultation with their colleagues, via an on-line survey and attended a priority setting workshop. Submitted uncertainties were collated, sorted and categorised according professional group. On the day of the workshop, participants were divided into four groups depending on their profession. Uncertainties submitted by their professional group were viewed, discussed and amended, prior to the first of three individual voting rounds. Participants cast up to ten votes for the uncertainties they judged as being high priority. Continuing in the professional groups, the top 10 uncertainties from each group were displayed, and the process was repeated. Groups were then brought together for a plenary session in which the final priorities were individually scored on a scale of 0-10 by participants. Priorities were ranked and results presented. Nominal group technique was used for generating the final uncertainties, voting and discussions.Thirty-three participants attended the workshop comprising; 10 specialist nurses, 10 district

  5. Rapid research and implementation priority setting for wound care uncertainties

    Science.gov (United States)

    Dumville, Jo C.; Christie, Janice; Cullum, Nicky A.

    2017-01-01

    Introduction People with complex wounds are more likely to be elderly, living with multimorbidity and wound related symptoms. A variety of products are available for managing complex wounds and a range of healthcare professionals are involved in wound care, yet there is a lack of good evidence to guide practice and services. These factors create uncertainty for those who deliver and those who manage wound care. Formal priority setting for research and implementation topics is needed to more accurately target the gaps in treatment and services. We solicited practitioner and manager uncertainties in wound care and held a priority setting workshop to facilitate a collaborative approach to prioritising wound care-related uncertainties. Methods We recruited healthcare professionals who regularly cared for patients with complex wounds, were wound care specialists or managed wound care services. Participants submitted up to five wound care uncertainties in consultation with their colleagues, via an on-line survey and attended a priority setting workshop. Submitted uncertainties were collated, sorted and categorised according professional group. On the day of the workshop, participants were divided into four groups depending on their profession. Uncertainties submitted by their professional group were viewed, discussed and amended, prior to the first of three individual voting rounds. Participants cast up to ten votes for the uncertainties they judged as being high priority. Continuing in the professional groups, the top 10 uncertainties from each group were displayed, and the process was repeated. Groups were then brought together for a plenary session in which the final priorities were individually scored on a scale of 0–10 by participants. Priorities were ranked and results presented. Nominal group technique was used for generating the final uncertainties, voting and discussions. Results Thirty-three participants attended the workshop comprising; 10 specialist nurses

  6. Developing rapid methods for analyzing upland riparian functions and values.

    Science.gov (United States)

    Hruby, Thomas

    2009-06-01

    Regulators protecting riparian areas need to understand the integrity, health, beneficial uses, functions, and values of this resource. Up to now most methods providing information about riparian areas are based on analyzing condition or integrity. These methods, however, provide little information about functions and values. Different methods are needed that specifically address this aspect of riparian areas. In addition to information on functions and values, regulators have very specific needs that include: an analysis at the site scale, low cost, usability, and inclusion of policy interpretations. To meet these needs a rapid method has been developed that uses a multi-criteria decision matrix to categorize riparian areas in Washington State, USA. Indicators are used to identify the potential of the site to provide a function, the potential of the landscape to support the function, and the value the function provides to society. To meet legal needs fixed boundaries for assessment units are established based on geomorphology, the distance from "Ordinary High Water Mark" and different categories of land uses. Assessment units are first classified based on ecoregions, geomorphic characteristics, and land uses. This simplifies the data that need to be collected at a site, but it requires developing and calibrating a separate model for each "class." The approach to developing methods is adaptable to other locations as its basic structure is not dependent on local conditions.

  7. Research and development program 1985

    International Nuclear Information System (INIS)

    1984-01-01

    In this report the research and development program of the GSI Darmstadt is described. It concerns heavy ion reactions, nuclear structure studies, exotic nuclei, nuclear theory, atomic collisions with heavy ions, atomic spectroscopy, the interaction of heavy ions with matter, atomic theory, biological studies with heavy ions, nuclear track techniques, UNILAC developments, acquisition of experimental data, and the development of new accelerators, ion sources, targets, and detectors. (HSI) [de

  8. Doctoral research on cadastral development

    DEFF Research Database (Denmark)

    Cagdas, Volkan; Stubkjær, Erik

    2009-01-01

    of the countries concerned. The cadastre, however, is the core of both systems as it provides for systematic and official descriptions of land parcels or real property units. The research mentioned often has a development perspective, and in this article we will motivate the introduction of the research domain...... of cadastral development. This research is multi-disciplinary and draws on elements of theories and methodologies from the natural, the social, the behavioral, and the formal sciences. During the last decade or so, doctoral dissertations have come to constitute a substantial part of this research effort...... with a call for a shared terminology and a shared set of concepts which may contribute to further theory building within the cadastral domain. Udgivelsesdato: OCT...

  9. RAPIDE 0.0 RHIC Accelerator Physics Intrepid Development Environment

    Energy Technology Data Exchange (ETDEWEB)

    Satogata, T. [Brookhaven National Lab. (BNL), Upton, NY (United States); Saltmarsh, C. [Brookhaven National Lab. (BNL), Upton, NY (United States); Peggs, S. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    1993-08-01

    This document is a guide to the common environmental features of computing in (and around) the RHIC Accelerator Physics.sectio on the 'zoo' cluster of UNJX workstations, in RAPIDE, the RHIC Accelerator Physics Intrepid Development Environment It is hoped tliat later revisions of this document will approach a more professional 'style guide', beyond the convenient collection of pointers and hints presented here. RAP does two kinds of computing, "controls" and "general", addressed in sections 2 and 3 of this document For general computing, efficient system administration requires cooperation in using a common environment There is a much stronger need to define - and adhere to - a commonly agreed set of styles (or rules) in developing controls software. Right now, these rules have been set "de facto". Future improvements to the controls environment, particularly in response to the opinions of users, depends on broad knowledge of what the rules are. There are environmental issues that are basic to both controls and general computing, and that are so fundamental that they are (almost) unarguable. They are described immediately below, in the next section.

  10. UCLA accelerator research and development

    International Nuclear Information System (INIS)

    Cline, D.B.

    1992-01-01

    This progress report covers work supported by the above DOE grant over the period November 1, 1991 to July 31, 1992. The work is a program of experimental and theoretical studies in advanced particle accelerator research and development for high energy physics applications. The program features research at particle beam facilities in the United States and includes research on novel high power sources, novel focussing systems (e.g. plasma lens), beam monitors, novel high brightness, high current gun systems, and novel flavor factories in particular the φ Factory

  11. NGNP Research and Development Status

    Energy Technology Data Exchange (ETDEWEB)

    David A. Petti

    2010-08-01

    At the inception of the Next Generation Nuclear Plant (NGNP) project, experts from the Department of Energy (DOE) national laboratories, gas reactor vendors, and universities collaborated to establish technology research and development (R&D) roadmaps. These roadmaps outlined the testing and computational development activities needed to qualify the materials and validate the modeling and simulation tools to be used in the design and safe operation of the NGNP, a helium-cooled, high temperature gas reactor (HTGR).

  12. Developing Effective Undergraduate Research Experience

    Science.gov (United States)

    Evans, Michael; Ilie, Carolina C.

    2011-03-01

    Undergraduate research is a valuable educational tool for students pursuing a degree in physics, but these experiences can become problematic and ineffective if not handled properly. Undergraduate research should be planned as an immersive learning experience in which the student has the opportunity to develop his/her skills in accordance with their interests. Effective undergraduate research experiences are marked by clear, measurable objectives and frequent student-professor collaboration. These objectives should reflect the long and short-term goals of the individual undergraduates, with a heightened focus on developing research skills for future use. 1. Seymour, E., Hunter, A.-B., Laursen, S. L. and DeAntoni, T. (2004), ``Establishing the benefits of research experiences for undergraduates in the sciences: First findings from a three-year study''. Science Education, 88: 493--534. 2. Behar-Horenstein, Linda S., Johnson, Melissa L. ``Enticing Students to Enter Into Undergraduate Research: The Instrumentality of an Undergraduate Course.'' Journal of College Science Teaching 39.3 (2010): 62-70.

  13. RAPID FREEFORM SHEET METAL FORMING: TECHNOLOGY DEVELOPMENT AND SYSTEM VERIFICATION

    Energy Technology Data Exchange (ETDEWEB)

    Kiridena, Vijitha [Ford Scientific Research Lab., Dearborn, MI (United States); Verma, Ravi [Boeing Research and Technology (BR& T), Seattle, WA (United States); Gutowski, Timothy [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Roth, John [Pennsylvania State Univ., University Park, PA (United States)

    2018-03-31

    The objective of this project is to develop a transformational RApid Freeform sheet metal Forming Technology (RAFFT) in an industrial environment, which has the potential to increase manufacturing energy efficiency up to ten times, at a fraction of the cost of conventional technologies. The RAFFT technology is a flexible and energy-efficient process that eliminates the need for having geometry-specific forming dies. The innovation lies in the idea of using the energy resource at the local deformation area which provides greater formability, process control, and process flexibility relative to traditional methods. Double-Sided Incremental Forming (DSIF), the core technology in RAFFT, is a new concept for sheet metal forming. A blank sheet is clamped around its periphery and gradually deformed into a complex 3D freeform part by two strategically aligned stylus-type tools that follow a pre-described toolpath. The two tools, one on each side of the blank, can form a part with sharp features for both concave and convex shapes. Since deformation happens locally, the forming force at any instant is significantly decreased when compared to traditional methods. The key advantages of DSIF are its high process flexibility, high energy-efficiency, low capital investment, and the elimination of the need for massive amounts of die casting and machining. Additionally, the enhanced formability and process flexibility of DSIF can open up design spaces and result in greater weight savings.

  14. Aniline Is Rapidly Converted Into Paracetamol Impairing Male Reproductive Development.

    Science.gov (United States)

    Holm, Jacob Bak; Chalmey, Clementine; Modick, Hendrik; Jensen, Lars Skovgaard; Dierkes, Georg; Weiss, Tobias; Jensen, Benjamin Anderschou Holbech; Nørregård, Mette Marie; Borkowski, Kamil; Styrishave, Bjarne; Martin Koch, Holger; Mazaud-Guittot, Severine; Jegou, Bernard; Kristiansen, Karsten; Kristensen, David Møbjerg

    2015-11-01

    Industrial use of aniline is increasing worldwide with production estimated to surpass 5.6 million metric tons in 2016. Exposure to aniline occurs via air, diet, and water augmenting the risk of exposing a large number of individuals. Early observations suggest that aniline is metabolized to paracetamol/acetaminophen, likely explaining the omnipresence of low concentrations of paracetamol in European populations. This is of concern as recent studies implicate paracetamol as a disrupter of reproduction. Here, we show through steroidogenic profiling that exposure to aniline led to increased levels of the Δ4 steroids, suggesting that the activity of CYP21 was decreased. By contrast, paracetamol decreased levels of androgens likely through inhibition of CYP17A1 activity. We confirm that aniline in vivo is rapidly converted to paracetamol by the liver. Intrauterine exposure to aniline and paracetamol in environmental and pharmaceutical relevant doses resulted in shortening of the anogenital distance in mice, a sensitive marker of fetal androgen levels that in humans is associated with reproductive malformations and later life reproductive disorders. In conclusion, our results provide evidence for a scenario where aniline, through its conversion into antiandrogenic paracetamol, impairs male reproductive development. © The Author 2015. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  15. Penggunaan Metode Rapid Application Development Dalam Perancangan Sistem Informasi Perpustakaan

    Directory of Open Access Journals (Sweden)

    Reza Trimahardhika

    2017-09-01

    Abstract Yayasan Putra Asih Malida in library data processing both in data processing member, book loaning, returning book until making report still using manual method and still using paper media to recording existing data in library. This will certainly slow down the process. On the other hand, students also find it difficult to find a book to read because they do not know where the storage is. To solve the problem it is necessary to create a library information system design that can handle the data processing library so that the process runs efficiently and effectively. In addition to saving expenses to buy paper, this system can also make old archives stored neatly than to be stored in a closet or Warehouse. In the design of information systems libraries based on this wab, the authors use Rapid Application Development (RAD, Netbeans 8.1 application as a script-making software and Xampp 1.7.3 as a software-based database creation MYSQL. The results of this information system design can provide ease of the officers in processing data related to the processing of libraries and can simplify and accelerate and can save time in making reports, and data can be stored safely because it is using the database so that officers do not have to worry about the loss data.   Keywords: System, Information, Library, Web, RAD

  16. Suborbital Research and Development Opportunities

    Science.gov (United States)

    Davis, Jeffrey R.

    2011-01-01

    This slide presentation reviews the new strategies for problem solving in the life sciences in the suborbital realm. Topics covered are: an overview of the space life sciences, the strategic initiatives that the Space Life Sciences organization engaged in, and the new business model that these initiatives were developed. Several opportunities for research are also reviewed.

  17. New laser research and development

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    New types of lasers must be developed to provide the desired energy per pulse, pulse length, pulse shape, wavelength, and efficiency for laser-fusion applications. This advanced laser research has focused on rare-gas oxides and on Hg 2 excimers

  18. Global research and development budget

    Energy Technology Data Exchange (ETDEWEB)

    Norman, C

    1980-03-01

    The future political and economic relationships between industrial countries and between the industrial and developing countries will be influenced by the investments now being made for research and development (R and D). There is little public understanding of this $150 billion global investment, 25 percent of which is spent on military programs, 15 percent on basic research, and nearly 10 percent on space exploration, while the most-pressing world problems are receiving relatively little attention. A breakdown of geographic distribution of research and a comparison of government expenditures for different areas of R and D reveals a situation that could be corrected. National and corporate priorities need to be revised and political and institutional barriers must give way to new international and cooperative arrangements. 3 tables, 27 references. (DCK)

  19. Feasibility of rapid ethical assessment for the Ethiopian health research ethics review system.

    Science.gov (United States)

    Addissie, Adamu; Davey, Gail; Newport, Melanie; Farsides, Bobbie; Feleke, Yeweyenhareg

    2015-01-01

    One of the challenges in the process of ethical medical research in developing countries, including Ethiopia, is translating universal principles of medical ethics into appropriate informed consent documents and their implementation. Rapid Ethical Assessment (REA) has been suggested as a feasible approach to meet this application gap. In the past few years REA has been employed in few research project in Ethiopia and have been found to be a useful and practical approach. Feasibility assessment of REA for the Ethiopian research setting was conducted between 2012-2013 in order to inform the subsequent introduction of REA into research ethics review and governance system in the country. REA was found to be an appropriate, relevant and feasible venture. We argue that REA can be integrated as part of the ethics review and governance system in Ethiopia. REA tools and techniques are considered relevant and acceptable to the Ethiopian research community, with few practical challenges anticipated in their implementation. REA are considered feasible for integration in the Ethiopian ethics review system.

  20. Research and Development in the Anthropogenic Cryosphere

    Science.gov (United States)

    de Jong, C.; Luthe, T.; Hohenwallne, D.

    2009-04-01

    Much of todays cryosphere research is oriented towards the polar regions and is strongly supported by large associations and funding. On the other hand, funding and institutional support is still limited for mountains. In Europe, mountain research is mainly funded through Alpine Space Interregs, FP7, ESF and COST. However, there is growing global change pressure on mountain regions, particularly in the more fragile, higher altitudes such as between 1000 - 3200 m in the Alps. Although these zones are comparable to the Arctic in terms of climatic and physiographic conditions, they are not in terms of human pressures and atmospheric pollution released from surrounding agglomerations. A re-orientation of research into more applied projects that tackle present day problems is necessary. Not only is climate change rapidly changing the face of mountains, socio-economic multipliers are also acting fast. New problems such as conflicts over natural resources are evolving at a rapid rate, requiring research funding and projects to respond at according rates if timely and efficient solutions are to be proposed. Other problems include contamination of high altitude lakes and ecosystems through atmospheric precipitation of persistent organic pollutants and concentration of radio-active substances. The rapid melt of glacier ice is also releasing pollutants that have been captured for many decades. Many of the present day problems develop due to a miscomprehension of the cryosphere. Short-term economical reasoning outweighs the long-term ecological impacts that could be very counter-productive at the long term. Both the glaciological, snow, permafrost, geomorphological, ecological, hydrological and atmospheric conditions are increasingly heavily modified by human impacts. The effects include the alteration of the ice cover (by artificial covering of glaciers), production of artificial snow cover, snow and ground compaction, erosion, landsliding, change in vegetation cover and

  1. Classroom Research and Professional Development

    Directory of Open Access Journals (Sweden)

    Omaira Vergara Luján

    2009-04-01

    Full Text Available This article intends to share the experience of a group of teachers in the Classroom Research Seminar of the Teacher Development Program in English carried out at Universidad del Valle, Cali, from January to June, 2007. The seminar was part of a high-level in-service program for teachers of English of a network of private educational institutions. We would like to share the highlights and difficulties of the experience. We will start with the general framework of the program and the concept of professional development that underlies it. Next we will focus on the classroom research seminar, its objectives, methodology and results. Finally we share the voices of some of the participants, who talk about the influence this seminar had on their professional development and daily work.

  2. Engineering research, development and technology

    International Nuclear Information System (INIS)

    1994-05-01

    The mission of the Engineering Research, Development, and Technology Program at Lawrence Livermore National Laboratory (LLNL) is to develop the technical staff, tools, and facilities needed to support current and future LLNL programs. The efforts are guided by a dual-benefit research and development strategy that supports Department of Energy missions, such as national security through nuclear deterrence and economic competitiveness through partnerships with U.S. industry. This annual report, organized by thrust area, describes the activities for the fiscal year 1993. The report provides timely summaries of objectives, methods, and results from nine thrust areas for this fiscal year: Computational Electronics and Electromagnetics; Computational Mechanics; Diagnostics and Microelectronics; Fabrication Technology; Materials Science and Engineering; Power Conversion Technologies; Nondestructive Evaluation; Remote Sensing, Imaging, and Signal Engineering; and Emerging Technologies. Separate abstracts were prepared for 47 papers in this report

  3. Rapid Cycle Amine (RCA) 3.0 System Development

    Science.gov (United States)

    Chullen, Cinda; Campbell, Colin; Papale, William; Hawes, Kevin; Wichowski, Robert

    2015-01-01

    The Rapid Cycle Amine (RCA) 3.0 system is currently under development by NASA, the Lyndon B. Johnson Space Center (JSC) in conjunction with United Technologies Corporation Aerospace Systems (UTAS). The RCA technology is a new carbon dioxide (CO2) and humidity removal system that has been baselined for the Advanced Extravehicular Mobility Unit (AEMU) Portable Life Support System. The evolution of the RCA development has progressed through several iterations of technology readiness levels including RCA 1.0, RCA 2.0, and RCA 3.0 test articles. The RCA is an advancement over currently technologies due to its unique regeneration capability. The RCA is capable of simultaneously removing CO2 and humidity from an influent air steam and subsequent regeneration when exposed to a vacuum source. The RCA technology uses two solid amine sorbent beds in an alternating fashion to adsorb CO2 and water (uptake mode) and desorb CO2 and water (regeneration mode) at the same time. The two beds operate in an efficient manner so that while one bed is in the uptake mode, the other is in the regeneration mode, thus continuously providing an on-service sorbent bed by which CO2 and humidity may be removed. The RCA 2.0 and 3.0 test articles were designed with a novel valve assembly which allows for switching between uptake and regeneration modes with only one moving part while minimizing gas volume losses to the vacuum source by means of an internal pressure equalization step during actuation. The RCA technology also is low power, small, and has performed extremely well in all development testing thus far. A final design was selected for the RCA 3.0, fabricated, assembled, and performance tested in 2014 with delivery to NASAJSC in January 2015. This paper will provide an overview on the RCA 3.0 system design and results of pre-delivery testing with references to the development of RCA 1.0 and RCA 2.0.

  4. Rapid microbiological testing: monitoring the development of bacterial stress.

    Directory of Open Access Journals (Sweden)

    Boris Zavizion

    2010-10-01

    Full Text Available The ability to respond to adverse environments effectively along with the ability to reproduce are sine qua non conditions for all sustainable cellular forms of life. Given the availability of an appropriate sensing modality, the ubiquity and immediacy of the stress response could form the basis for a new approach for rapid biological testing. We have found that measuring the dielectric permittivity of a cellular suspension, an easily measurable electronic property, is an effective way to monitor the response of bacterial cells to adverse conditions continuously. The dielectric permittivity of susceptible and resistant strains of Escherichia coli and Staphylococcus aureus, treated with gentamicin and vancomycin, were measured directly using differential impedance sensing methods and expressed as the Normalized Impedance Response (NIR. These same strains were also heat-shocked and chemically stressed with Triton X-100 or H(2O(2. The NIR profiles obtained for antibiotic-treated susceptible organisms showed a strong and continuous decrease in value. In addition, the intensity of the NIR value decrease for susceptible cells varied in proportion to the amount of antibiotic added. Qualitatively similar profiles were found for the chemically treated and heat-shocked bacteria. In contrast, antibiotic-resistant cells showed no change in the NIR values in the presence of the drug to which it is resistant. The data presented here show that changes in the dielectric permittivity of a cell suspension are directly correlated with the development of a stress response as well as bacterial recovery from stressful conditions. The availability of a practical sensing modality capable of monitoring changes in the dielectric properties of stressed cells could have wide applications in areas ranging from the detection of bacterial infections in clinical specimens to antibiotic susceptibility testing and drug discovery.

  5. Internationalization of Research and Development

    DEFF Research Database (Denmark)

    Håkanson, Lars

    2014-01-01

    with geographically dispersed and organizationally decentralized R&D. A simple typology of foreign R&D units is presented, emphasizing that the opportunities and challenges vary with the nature of their tasks, which range from technical support and local adaptation of products and processes to product development and......, in some cases, applied and basic research. Managerial systems, procedures, and practices for coordination and control of internationally decentralized R&D are identified, along with mechanisms promoting knowledge management, problem solving, and innovation....

  6. Gender | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Asian Development Bank ... Women and children riding the Lahore Bus Rapid Transit ( Lahore Metro Bus) service. ... of economic growth for developing countries, they are also frequently the site of growing violence, poverty, and inequality.

  7. Bus rapid transit and development : policies and practices that affect development around transit.

    Science.gov (United States)

    2009-12-01

    The development of Bus Rapid Transit (BRT) systems is relatively recent in the United States, but several systems are in operation and more are advancing. There is a need for a more comprehensive understanding of the relationship between land use and...

  8. Search Results | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 1 - 10 of 8533 ... Research findings illustrate how environmental degradation and insecure ... Healing and resilience in situations of conflict and displacement ... Rapid global urbanization presents important social, environmental, and ...

  9. Legitimation for Early and Rapid Internationalization: A Review of Research in International Entrepreneurship

    DEFF Research Database (Denmark)

    Laine, Igor; Kuivalainen, Olli; Marinova, Svetla Trifonova

    In this paper we respond to Cavusgil and Knight’s call for future research to address the question of born global firms overcome inherent liabilities to achieve legitimacy in foreign markets. To contribute to this call, we have systematically reviewed the extant international entrepreneurship...... literature. By analyzing existing evidence on building organizational legitimacy by early and rapidly internationalizing firms, our review helps to understand reasons and underlying mechanisms of successful legitimation of early and rapid internationalization thus ultimately explaining existence...... entrepreneurship....

  10. Advanced accelerator research and development

    International Nuclear Information System (INIS)

    Anon.

    1974-01-01

    Research and development on the Positron-Electron Project (PEP), the electron rings, the superconducting accelerator (ESCAR), and the superconductivity program are reported. Efforts relating to the proposed PEP include work on: (1) the injection system; (2) the rf system; (3) the main-ring bend magnets; (4) the magnet power supplies and controls; (5) alignment; (6) radiation and shielding; (7) the vacuum system; and (8) conventional facilities (utilities, etc.). Experimental and theoretical work continued on the development of suitably intense electron rings as vehicles for the collective acceleration of ions. The most difficult problem was found to be the longitudinal (negative mass) instability. Design work was begun for ESCAR (Experimental Superconducting Accelerating Ring), a small proton synchrotron and storage ring using superconducting magnets, which should aid in the design of future large superconducting facilities. Magnet development was largely directed toward the detailed design of the dipole units. A superconducting beam transport line was installed at the Bevatron. (PMA)

  11. Development of rapid urine analysis method for uranium

    Energy Technology Data Exchange (ETDEWEB)

    Kuwabara, J.; Noguchi, H. [Japan Atomic Energy Research Institute, Tokai, Ibaraki (Japan)

    2000-05-01

    ICP-MS has begun to spread in the field of individual monitoring for internal exposure as a very effective machine for uranium analysis. Although the ICP-MS has very high sensitivity, it requires longer time than conventional analysis, such as fluorescence analysis, because it is necessary to remove matrix from a urine sample sufficiently. To shorten time required for the urine bioassay by ICP-MS, a rapid uranium analysis method using the ICP-MS connected with a flow injection system was developed. Since this method does not involve chemical separation steps, the time required is equivalent to the conventional analysis. A measurement test was carried out using 10 urine solutions prepared from a urine sample. Required volume of urine solution is 5 ml. Main chemical treatment is only the digestion with 5 ml of nitric acid using a microwave oven to decompose organic matter and to dissolve suspended or precipitated matter. The microwave oven can digest 10 samples at once within an hour. Volume of digested sample solution was adjusted to 10 ml. The prepared sample solutions were directly introduced to the ICP-MS without any chemical separation procedure. The ICP-MS was connected with a flow injection system and an auto sampler. The flow injection system can minimize the matrix effects caused from salt dissolved in high matrix solution, such as non chemical separated urine sample, because it can introduce micro volume of sample solution into the ICP-MS. The ICP-MS detected uranium within 2 min/sample using the auto sampler. The 10 solutions prepared from a urine sample showed an average of 7.5 ng/l of uranium concentration in urine with 10 % standard deviation. A detection limit is about 1 ng/l. The total time required was less than 4 hours for 10 sample analysis. In the series of measurement, any memory effect was not observed. The present analysis method using the ICP-MS equipped with the flow injection system demonstrated that the shortening of time required on high

  12. Development of rapid urine analysis method for uranium

    International Nuclear Information System (INIS)

    Kuwabara, J.; Noguchi, H.

    2000-01-01

    ICP-MS has begun to spread in the field of individual monitoring for internal exposure as a very effective machine for uranium analysis. Although the ICP-MS has very high sensitivity, it requires longer time than conventional analysis, such as fluorescence analysis, because it is necessary to remove matrix from a urine sample sufficiently. To shorten time required for the urine bioassay by ICP-MS, a rapid uranium analysis method using the ICP-MS connected with a flow injection system was developed. Since this method does not involve chemical separation steps, the time required is equivalent to the conventional analysis. A measurement test was carried out using 10 urine solutions prepared from a urine sample. Required volume of urine solution is 5 ml. Main chemical treatment is only the digestion with 5 ml of nitric acid using a microwave oven to decompose organic matter and to dissolve suspended or precipitated matter. The microwave oven can digest 10 samples at once within an hour. Volume of digested sample solution was adjusted to 10 ml. The prepared sample solutions were directly introduced to the ICP-MS without any chemical separation procedure. The ICP-MS was connected with a flow injection system and an auto sampler. The flow injection system can minimize the matrix effects caused from salt dissolved in high matrix solution, such as non chemical separated urine sample, because it can introduce micro volume of sample solution into the ICP-MS. The ICP-MS detected uranium within 2 min/sample using the auto sampler. The 10 solutions prepared from a urine sample showed an average of 7.5 ng/l of uranium concentration in urine with 10 % standard deviation. A detection limit is about 1 ng/l. The total time required was less than 4 hours for 10 sample analysis. In the series of measurement, any memory effect was not observed. The present analysis method using the ICP-MS equipped with the flow injection system demonstrated that the shortening of time required on high

  13. Rapid gas development in the Fayetteville shale basin, Arkansas

    Science.gov (United States)

    Advances in drilling and extraction of natural gas have resulted in rapid expansion of wells in shale basins. The rate of gas well installation in the Fayetteville shale is 774 wells a year since 2005 with thousands more planned. The Fayetteville shale covers 23,000 km2 although ...

  14. Development of rapid phenotypic system for the identification

    Indian Academy of Sciences (India)

    Rapid and accurate identification of bacterial pathogens is a fundamental goal of clinical microbiology. The diagnosis and surveillance of diseases is dependent, to a great extent, on laboratory services, which cannot function without effective reliable reagents and diagnostics. Despite the advancement in microbiology ...

  15. Advanced Research Reactor Fuel Development

    Energy Technology Data Exchange (ETDEWEB)

    Kim, C. K.; Park, H. D.; Kim, K. H. (and others)

    2006-04-15

    RERTR program for non-proliferation has propelled to develop high-density U-Mo dispersion fuels, reprocessable and available as nuclear fuel for high performance research reactors in the world. As the centrifugal atomization technology, invented in KAERI, is optimum to fabricate high-density U-Mo fuel powders, it has a great possibility to be applied in commercialization if the atomized fuel shows an acceptable in-reactor performance in irradiation test for qualification. In addition, if rod-type U-Mo dispersion fuel is developed for qualification, it is a great possibility to export the HANARO technology and the U-Mo dispersion fuel to the research reactors supplied in foreign countries in future. In this project, reprocessable rod-type U-Mo test fuel was fabricated, and irradiated in HANARO. New U-Mo fuel to suppress the interaction between U-Mo and Al matrix was designed and evaluated for in-reactor irradiation test. The fabrication process of new U-Mo fuel developed, and the irradiation test fuel was fabricated. In-reactor irradiation data for practical use of U-Mo fuel was collected and evaluated. Application plan of atomized U-Mo powder to the commercialization of U-Mo fuel was investigated.

  16. Development Model for Research Infrastructures

    Science.gov (United States)

    Wächter, Joachim; Hammitzsch, Martin; Kerschke, Dorit; Lauterjung, Jörn

    2015-04-01

    Research infrastructures (RIs) are platforms integrating facilities, resources and services used by the research communities to conduct research and foster innovation. RIs include scientific equipment, e.g., sensor platforms, satellites or other instruments, but also scientific data, sample repositories or archives. E-infrastructures on the other hand provide the technological substratum and middleware to interlink distributed RI components with computing systems and communication networks. The resulting platforms provide the foundation for the design and implementation of RIs and play an increasing role in the advancement and exploitation of knowledge and technology. RIs are regarded as essential to achieve and maintain excellence in research and innovation crucial for the European Research Area (ERA). The implementation of RIs has to be considered as a long-term, complex development process often over a period of 10 or more years. The ongoing construction of Spatial Data Infrastructures (SDIs) provides a good example for the general complexity of infrastructure development processes especially in system-of-systems environments. A set of directives issued by the European Commission provided a framework of guidelines for the implementation processes addressing the relevant content and the encoding of data as well as the standards for service interfaces and the integration of these services into networks. Additionally, a time schedule for the overall construction process has been specified. As a result this process advances with a strong participation of member states and responsible organisations. Today, SDIs provide the operational basis for new digital business processes in both national and local authorities. Currently, the development of integrated RIs in Earth and Environmental Sciences is characterised by the following properties: • A high number of parallel activities on European and national levels with numerous institutes and organisations participating

  17. Taxation of Research and Development

    Directory of Open Access Journals (Sweden)

    Zsuzsanna Szeles

    2016-01-01

    Full Text Available Research and development plays an unquestionably role in terms of long-term growth. According to Eurostat, almost half of all enterprises in the EU-28 reported innovation activity (48.9% during the period 2010-2012. Compared with the period 2008-2010, the share of innovative enterprises decreased by 3.9 percentage points. Among the EU Member States, the highest shares of innovative enterprises during the period 2010–2012 were observed in Germany (66.9 % of all enterprises, and the lowest share was recorded in Romania (20.7%.

  18. Participatory Research and Development for Sustainable Agriculture ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Participatory Research and Development for Sustainable Agriculture and Natural Resource Management - A Sourcebook Volume 3 : Doing Participatory Research and Development. Couverture du livre Participatory Research and Development for Sustainable Agriculture and Natural Resource Management : A.

  19. Laboratory directed research and development

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-15

    The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory's R D capabilities, and further the development of its strategic initiatives. Among the aims of the projects supported by the Program are establishment of engineering proof-of-principle''; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these project are closely associated with major strategic thrusts of the Laboratory as described in Argonne's Five Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne. Areas of emphasis are (1) advanced accelerator and detector technology, (2) x-ray techniques in biological and physical sciences, (3) advanced reactor technology, (4) materials science, computational science, biological sciences and environmental sciences. Individual reports summarizing the purpose, approach, and results of projects are presented.

  20. Software development for research reactors

    International Nuclear Information System (INIS)

    Krohn, J.L.; Feltz, D.E.; Khalil, N.S.

    1986-01-01

    The Texas A and M University Nuclear Science Center, in a program jointly sponsored with the International Atomic Energy Agency, is developing a series of computer software programs of use at research reactor facilities. The programs cover a wide range of topics including activation and shielding calculations, control rod calibrations, power calorimetrics, and fuel inventory including burnup. Many of the programs are modified and improved versions of programs already in use at the NSC that ran on outdated computing equipment. All of the new versions were written in Fortran77 on the NSC's new TI Pro microcomputer and are IBM-compatible. This paper describes the development and translation efforts in preparing the programs for use by other facilities, and gives an overview of the aim of the development effort. A brief description of each program that has been or is to be written is given including the required inputs and the resulting outputs. This paper also addresses the original needs that brought about the development program and the benefits to facility operations that each program provides. The programs discussed are available to interested parties in a hard-copy listing as requested. (author)

  1. Advances in developing rapid, reliable and portable detection systems for alcohol.

    Science.gov (United States)

    Thungon, Phurpa Dema; Kakoti, Ankana; Ngashangva, Lightson; Goswami, Pranab

    2017-11-15

    Development of portable, reliable, sensitive, simple, and inexpensive detection system for alcohol has been an instinctive demand not only in traditional brewing, pharmaceutical, food and clinical industries but also in rapidly growing alcohol based fuel industries. Highly sensitive, selective, and reliable alcohol detections are currently amenable typically through the sophisticated instrument based analyses confined mostly to the state-of-art analytical laboratory facilities. With the growing demand of rapid and reliable alcohol detection systems, an all-round attempt has been made over the past decade encompassing various disciplines from basic and engineering sciences. Of late, the research for developing small-scale portable alcohol detection system has been accelerated with the advent of emerging miniaturization techniques, advanced materials and sensing platforms such as lab-on-chip, lab-on-CD, lab-on-paper etc. With these new inter-disciplinary approaches along with the support from the parallel knowledge growth on rapid detection systems being pursued for various targets, the progress on translating the proof-of-concepts to commercially viable and environment friendly portable alcohol detection systems is gaining pace. Here, we summarize the progress made over the years on the alcohol detection systems, with a focus on recent advancement towards developing portable, simple and efficient alcohol sensors. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Carbon sequestration research and development

    Energy Technology Data Exchange (ETDEWEB)

    Reichle, Dave; Houghton, John; Kane, Bob; Ekmann, Jim; and others

    1999-12-31

    Predictions of global energy use in the next century suggest a continued increase in carbon emissions and rising concentrations of carbon dioxide (CO{sub 2}) in the atmosphere unless major changes are made in the way we produce and use energy--in particular, how we manage carbon. For example, the Intergovernmental Panel on Climate Change (IPCC) predicts in its 1995 ''business as usual'' energy scenario that future global emissions of CO{sub 2} to the atmosphere will increase from 7.4 billion tonnes of carbon (GtC) per year in 1997 to approximately 26 GtC/year by 2100. IPCC also projects a doubling of atmospheric CO{sub 2} concentration by the middle of next century and growing rates of increase beyond. Although the effects of increased CO{sub 2} levels on global climate are uncertain, many scientists agree that a doubling of atmospheric CO{sub 2} concentrations could have a variety of serious environmental consequences. The goal of this report is to identify key areas for research and development (R&D) that could lead to an understanding of the potential for future use of carbon sequestration as a major tool for managing carbon emissions. Under the leadership of DOE, researchers from universities, industry, other government agencies, and DOE national laboratories were brought together to develop the technical basis for conceiving a science and technology road map. That effort has resulted in this report, which develops much of the information needed for the road map.

  3. Comparative Effectiveness Research, Genomics-Enabled Personalized Medicine, and Rapid Learning Health Care: A Common Bond

    Science.gov (United States)

    Ginsburg, Geoffrey S.; Kuderer, Nicole M.

    2012-01-01

    Despite stunning advances in our understanding of the genetics and the molecular basis for cancer, many patients with cancer are not yet receiving therapy tailored specifically to their tumor biology. The translation of these advances into clinical practice has been hindered, in part, by the lack of evidence for biomarkers supporting the personalized medicine approach. Most stakeholders agree that the translation of biomarkers into clinical care requires evidence of clinical utility. The highest level of evidence comes from randomized controlled clinical trials (RCTs). However, in many instances, there may be no RCTs that are feasible for assessing the clinical utility of potentially valuable genomic biomarkers. In the absence of RCTs, evidence generation will require well-designed cohort studies for comparative effectiveness research (CER) that link detailed clinical information to tumor biology and genomic data. CER also uses systematic reviews, evidence-quality appraisal, and health outcomes research to provide a methodologic framework for assessing biologic patient subgroups. Rapid learning health care (RLHC) is a model in which diverse data are made available, ideally in a robust and real-time fashion, potentially facilitating CER and personalized medicine. Nonetheless, to realize the full potential of personalized care using RLHC requires advances in CER and biostatistics methodology and the development of interoperable informatics systems, which has been recognized by the National Cancer Institute's program for CER and personalized medicine. The integration of CER methodology and genomics linked to RLHC should enhance, expedite, and expand the evidence generation required for fully realizing personalized cancer care. PMID:23071236

  4. Rapid development of medical imaging tools with open-source libraries.

    Science.gov (United States)

    Caban, Jesus J; Joshi, Alark; Nagy, Paul

    2007-11-01

    Rapid prototyping is an important element in researching new imaging analysis techniques and developing custom medical applications. In the last ten years, the open source community and the number of open source libraries and freely available frameworks for biomedical research have grown significantly. What they offer are now considered standards in medical image analysis, computer-aided diagnosis, and medical visualization. A cursory review of the peer-reviewed literature in imaging informatics (indeed, in almost any information technology-dependent scientific discipline) indicates the current reliance on open source libraries to accelerate development and validation of processes and techniques. In this survey paper, we review and compare a few of the most successful open source libraries and frameworks for medical application development. Our dual intentions are to provide evidence that these approaches already constitute a vital and essential part of medical image analysis, diagnosis, and visualization and to motivate the reader to use open source libraries and software for rapid prototyping of medical applications and tools.

  5. Research to support development of organic food and farming

    OpenAIRE

    Watson, Christine; Alrøe, Hugo; Kristensen, Erik Steen

    2006-01-01

    Agriculture and organic agriculture in particular are developing rapidly, due not only to technological change but also to changes in agricultural policy and public expectation. Research allows new knowledge to be developed and is thus vital for the future of organic agriculture. We can ask the question, what is the purpose of research on organic farming? Is it to increase yield and productivity, to compare it with other forms of agriculture, or to quantify its environmental and social impact...

  6. Research and Development. Annual Report 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This report discusses the research and development activities in which NVE has been involved in 2000. These activities fall into three categories: watercourse research, hydrological research and energy related research. The HYDRA research programme, which studied flooding and human intervention, is discussed in particular. The report includes a list of research and development reports that were published in 2000.

  7. Canada Research Chairs | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    aspx. International Research Chairs Initiative. The International Research Chairs Initiative pairs top research talent from universities in Canada with their counterparts in developing countries to address key development challenges. View more

  8. Database Development for Ocean Impacts: Imaging, Outreach, and Rapid Response

    Science.gov (United States)

    2012-09-30

    Timothy Stanton Woods Hole Oceanographic Institution Acoustics PUBLICATIONS 33 Refereed, Published Articles Supported through this award 2012...Laboratory for Translational Auditory Research, Journal of the American Academy of Audiology , vol.23, Issue 6, New York, p.422-437. [published

  9. Identification of pollutant sources in a rapidly developing urban river catchment in China

    Science.gov (United States)

    Huang, Jingshui; Yin, Hailong; Jomma, Seifeddine; Rode, Michael; Zhou, Qi

    2016-04-01

    Rapid economic development and urbanization worldwide cause serious ecological and environmental problems. A typical region that is in transition and requires systemic research for effective intervention is the rapidly developing city of Hefei in central P. R. China. In order to investigate the sources of pollutants over a one-year period in Nanfei River catchment that drains the city of Hefei, discharges were measured and water samples were taken and measured along the 14km river section at 10 sites for 4 times from 2013 to 2014. Overflow concentrations of combined sewer and separate storm drains were also measured by selecting 15 rain events in 4 typical drainage systems. Loads and budgets of water and different pollutant sources i.e., wastewater treatment plant (WWTP) effluent, urban drainage overflow, unknown wastewater were calculated. The water balance demonstrated that >70% of the discharge originated from WWTP effluent. Lack of clean upstream inflow thereby is threatening ecological safety and water quality. Furthermore, mass fluxes calculations revealed that >40% of the COD (Chemical Oxygen Demand) loads were from urban drainage overflow because of a large amount of discharge of untreated wastewater in pumping stations during rain events. WWTP effluent was the predominant source of the total nitrogen loads (>60%) and ammonia loads (>45%). However, the total phosphorous loads from three different sources are similar (˜1/3). Thus, our research provided a basis for appropriate and prior mitigation strategies (state-of-art of WWTP upgrade, sewer systems modification, storm water regulation and storage capacity improvement, etc.) for different precedence-controlled pollutants with the limited infrastructure investments in these rapidly developing urban regions.

  10. Using Modified Fagan Inspections to Control Rapid System Development

    Science.gov (United States)

    Griesel, M. A.; Welz, L. L.

    1994-01-01

    The Jet Propulsion Laboratory (JPL) has been developing new approaches to software and system development to shorten life cycle time and reduce total life-cycle cost, while maintaining product quality. One such approach has been taken by the Just-In-Time (JIT) Materiel Acquisition System Development Project.

  11. Development and Evaluation of a Rapid and Sensitive EBOV-RPA Test for Rapid Diagnosis of Ebola Virus Disease.

    Science.gov (United States)

    Yang, Mingjuan; Ke, Yuehua; Wang, Xuesong; Ren, Hang; Liu, Wei; Lu, Huijun; Zhang, Wenyi; Liu, Shiwei; Chang, Guohui; Tian, Shuguang; Wang, Lihua; Huang, Liuyu; Liu, Chao; Yang, Ruifu; Chen, Zeliang

    2016-06-01

    Confirming Ebola virus disease (EVD), a deadly infectious disease, requires real-time RT-PCR, which takes up to a few hours to yield results. Therefore, a rapid diagnostic assay is imperative for EVD diagnosis. A rapid nucleic acid test based on recombinase polymerase amplification (EBOV-RPA) was developed to specifically detect the 2014 outbreak strains. The EBOV-RPA assay was evaluated by testing samples from suspected EVD patients in parallel with RT-PCR. An EBOV-RPA, which could be completed in 20 min, was successfully developed. Of 271 patients who tested positive for Ebola virus by RT-PCR, 264 (sensitivity: 97%, 95% CI: 95.5-99.3%) were positive by EBOV-RPA; 101 of 104 patients (specificity: 97%, 95% CI: 93.9-100%) who tested negative by RT-PCR were also negative by EBOV-RPA. The sensitivity values for samples with a Ct value of RPA had significantly high Ct values. Results of external quality assessment samples with EBOV-RPA were 100%, consistent with those of RT-PCR. The EBOV-RPA assay showed 97% sensitivity and 97% specificity for all EVD samples tested, making it a rapid and sensitive test for EVD diagnosis.

  12. Research Engagement for School Development

    Science.gov (United States)

    Wilkins, Raphael

    2011-01-01

    This thought-provoking book examines the new and growing phenomenon of the "research-engaged school"--schools that not only encourage their staff to carry out their own research, but also use published research to inform practice and improve the quality of education. The author draws upon his scholarship and practice in local authorities, schools…

  13. Research and development and industrial informatization

    International Nuclear Information System (INIS)

    1995-08-01

    This book deals with research and development and industrial informatization with development of technology international trend, the present conditions of scientific technology in the major nations, politics of technical development and trend, process of national research and development, research for industrial research and development, strengthen cooperation for scientific technology among nations, current situation and development of technology by field such as energy, software and system, and technology for industrial informatization.

  14. Historical Development of Origins Research

    Science.gov (United States)

    Lazcano, Antonio

    2010-01-01

    Following the publication of the Origin of Species in 1859, many naturalists adopted the idea that living organisms were the historical outcome of gradual transformation of lifeless matter. These views soon merged with the developments of biochemistry and cell biology and led to proposals in which the origin of protoplasm was equated with the origin of life. The heterotrophic origin of life proposed by Oparin and Haldane in the 1920s was part of this tradition, which Oparin enriched by transforming the discussion of the emergence of the first cells into a workable multidisciplinary research program. On the other hand, the scientific trend toward understanding biological phenomena at the molecular level led authors like Troland, Muller, and others to propose that single molecules or viruses represented primordial living systems. The contrast between these opposing views on the origin of life represents not only contrasting views of the nature of life itself, but also major ideological discussions that reached a surprising intensity in the years following Stanley Miller’s seminal result which showed the ease with which organic compounds of biochemical significance could be synthesized under putative primitive conditions. In fact, during the years following the Miller experiment, attempts to understand the origin of life were strongly influenced by research on DNA replication and protein biosynthesis, and, in socio-political terms, by the atmosphere created by Cold War tensions. The catalytic versatility of RNA molecules clearly merits a critical reappraisal of Muller’s viewpoint. However, the discovery of ribozymes does not imply that autocatalytic nucleic acid molecules ready to be used as primordial genes were floating in the primitive oceans, or that the RNA world emerged completely assembled from simple precursors present in the prebiotic soup. The evidence supporting the presence of a wide range of organic molecules on the primitive Earth, including membrane

  15. South Asia | Page 194 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    It is the outcome of the collaborative PANdora research and development ... $200 US per capita, the Socialist Republic of Viet Nam is one of the world's poorest countries. ... role of foreign private-sector firms, especially from Japan and the United States, in the recent and rapid economic growth and integration in East Asia.

  16. Fatigue Life Prediction in Rapid Die Casting - Preliminary Work in View of Current Research

    International Nuclear Information System (INIS)

    Chuan Huat Ng; Grote, Karl-Heinrich; Baehr, Ruediger

    2007-01-01

    Numerical simulation technique as a prediction tool is slowly adopted in metal casting industry for predicting design modelling solidification analysis. The reasons for this activity is found in the need to further enhance the geometrical design and mechanical properties of the tool design and the correct prediction methodology to fulfil industrial needs. The present state of numerical simulation capabilities in rapid die casting technologies is reviewed and the failure mode mechanisms of thermal fatigue, aimed at developing a numerical simulation with a systematic design guidance for predicting the thermal cyclic loading analysis and improvement is presented along with several other methods. The economic benefits of a numerical simulation technique in die casting are limited to tool life time, mechanical properties and design guidance. The extensive computer capabilities of a numerical simulation with a systematic design guidance methodology are exploited to provide a solution for flexible design, mechanical properties and mould life time. Related research carried out worldwide by different organisations and academic institutions are discussed

  17. Web Developer | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Primary Duties or Responsibilities Web Development Leads all technical web ... design, and maintain the corporate website and any other internet properties IDRC ... and testing site for use by members of the website and social media team.

  18. Development of a Rapid Chemical Identification System (RCIS) for ...

    African Journals Online (AJOL)

    Methods: Three members of this group of drugs (tablet form) available in the Nigerian market and labelled MA and MB for metronidazole, T A and TB for ... of acetone, ethyl acetate and ammonia (100:5:1) and method B with mobile phase consisting of acetone, chloroform and ammonia (100:15:1) were developed for the ...

  19. Rapid dental development in a Middle Paleolithic Belgian Neanderthal.

    Science.gov (United States)

    Smith, Tanya M; Toussaint, Michel; Reid, Donald J; Olejniczak, Anthony J; Hublin, Jean-Jacques

    2007-12-18

    The evolution of life history (pace of growth and reproduction) was crucial to ancient hominin adaptations. The study of dental development facilitates assessment of growth and development in fossil hominins with greater precision than other skeletal analyses. During tooth formation, biological rhythms manifest in enamel and dentine, creating a permanent record of growth rate and duration. Quantification of these internal and external incremental features yields developmental benchmarks, including ages at crown completion, tooth eruption, and root completion. Molar eruption is correlated with other aspects of life history. Recent evidence for developmental differences between modern humans and Neanderthals remains ambiguous. By measuring tooth formation in the entire dentition of a juvenile Neanderthal from Scladina, Belgium, we show that most teeth formed over a shorter time than in modern humans and that dental initiation and eruption were relatively advanced. By registering manifestations of stress across the dentition, we are able to present a precise chronology of Neanderthal dental development that differs from modern humans. At 8 years of age at death, this juvenile displays a degree of development comparable with modern human children who are several years older. We suggest that age at death in juvenile Neanderthals should not be assessed by comparison with modern human standards, particularly those derived from populations of European origin. Moreover, evidence from the Scladina juvenile and other similarly aged hominins suggests that a prolonged childhood and slow life history are unique to Homo sapiens.

  20. Xeroderma Pigmentosum With Early And Rapid Development Of Malignancy

    Directory of Open Access Journals (Sweden)

    Ghosh Arghyaprasum

    2000-01-01

    Full Text Available A case of xeroderma pigmentosum in a 9 year old developing multiple tumours over a short period of 6 months is reported. The tumours showed two different types of malignancies-squamous cell carcinoma and malignant melanoma. Two other siblings exhibited cutaneous lesions of xeroderma pigmentosum without any malignant change.

  1. Evaluation of urban sprawl and urban landscape pattern in a rapidly developing region.

    Science.gov (United States)

    Lv, Zhi-Qiang; Dai, Fu-Qiang; Sun, Cheng

    2012-10-01

    Urban sprawl is a worldwide phenomenon happening particularly in rapidly developing regions. A study on the spatiotemporal characteristics of urban sprawl and urban pattern is useful for the sustainable management of land management and urban land planning. The present research explores the spatiotemporal dynamics of urban sprawl in the context of a rapid urbanization process in a booming economic region of southern China from 1979 to 2005. Three urban sprawl types are distinguished by analyzing overlaid urban area maps of two adjacent study years which originated from the interpretation of remote sensed images and vector land use maps. Landscape metrics are used to analyze the spatiotemporal pattern of urban sprawl for each study period. Study results show that urban areas have expanded dramatically, and the spatiotemporal landscape pattern configured by the three sprawl types changed obviously. The different sprawl type patterns in five study periods have transformed significantly, with their proportions altered both in terms of quantity and of location. The present research proves that urban sprawl quantification and pattern analysis can provide a clear perspective of the urbanization process during a long time period. Particularly, the present study on urban sprawl and sprawl patterns can be used by land use and urban planners.

  2. Enhancing water security in a rapidly developing shale gas region

    Directory of Open Access Journals (Sweden)

    Shannon Holding

    2017-06-01

    New hydrological insights for the region: Initiatives and tools enhancing water security in the region include strategic partnerships and stakeholder collaborations, policy and regulation development, and data collection and distribution efforts. The contributions and limitations of each of these are discussed. A vulnerability mapping framework is presented which addresses data gaps and provides a tool for decision-making surrounding risk to water quality from various hazards. An example vulnerability assessment was conducted for wastewater transport along pipeline and trucking corridors.

  3. Development of rapid high throughput biodosimetry tools for radiological triage

    International Nuclear Information System (INIS)

    Balajee, Adayabalam S.; Escalona, Maria; Smith, Tammy; Ryan, Terri; Dainiak, Nicholas

    2018-01-01

    Accidental or intentional radiological or nuclear (R/N) disasters constitute a major threat around the globe that can affect several tens, hundreds and thousands of humans. Currently available cytogenetic biodosimeters are time consuming and laborious to perform making them impractical for triage scenarios. Therefore, it is imperative to develop high throughput techniques which will enable timely assessment of personalized dose for making an appropriate 'life-saving' clinical decision

  4. ADVANCED AND RAPID DEVELOPMENT OF DYNAMIC ANALYSIS TOOLS FOR JAVA

    Directory of Open Access Journals (Sweden)

    Alex Villazón

    2012-01-01

    Full Text Available Low-level bytecode instrumentation techniques are widely used in many software-engineering tools for the Java Virtual Machine (JVM, that perform some form of dynamic program analysis, such as profilers or debuggers. While program manipulation at the bytecode level is very flexible, because the possible bytecode transformations are not restricted, tool development based on this technique is tedious and error-prone. As a promising alternative, the specification of bytecode instrumentation at a higher level using aspect-oriented programming (AOP can reduce tool development time and cost. Unfortunately, prevailing AOP frameworks lack some features that are essential for certain dynamic analyses. In this article, we focus on three common shortcomings in AOP frameworks with respect to the development of aspect-based tools - (1 the lack of mechanisms for passing data between woven advices in local variables, (2 the support for user-defined static analyses at weaving time, and (3 the absence of pointcuts at the level of individual basic blocks of code. We propose @J, an annotation-based AOP language and weaver that integrates support for these three features. The benefits of the proposed features are illustrated with concrete examples.

  5. Rapid Software Development for Experiment Control at OPAL

    International Nuclear Information System (INIS)

    Hathaway, P.V.; Lam, Tony; Franceschini, Ferdi; Hauser, Nick; Rayner, Hugh

    2005-01-01

    Full text: ANSTO is undertaking the parallel development of instrument control and graphical experiment interface software for seven neutron beam instruments at OPAL. Each instrument poses several challenges for a common system solution, including custom detector interfaces, a range of motion and beamline optics schema, and a spectrum of online data reduction requirements. To provide a superior system with the least development effort, the computing team have adopted proven, configurable, server-based control software (SICS)1., a highly Integrated Scientific Experimental Environment (GumTree)2. and industry-standard database management systems. The resulting graphical interfaces allow operation in a familiar experiment domain, with monitoring of data and parameters independent of control system specifics. GumTree presents the experimenter with a consistent interface for experiment management, instrument control and data reduction tasks. The facility instrument scientists can easily reconfigure instruments and add ancillaries. The user community can expect a reduced learning curve for performing each experiment. GumTree can be installed anywhere for pre-experiment familiarisation, postprocessing of acquired data sets, and integration with third party analysis tools. Instrument scientists are seeing faster software development iterations and have a solid basis to prepare for the next suite of instruments. 1. SICS from PSI (lns00.psi.ch). 2. GumTree (gumtree.sourceforge.net), new site: http://gumtree.sourceforge.net/wiki/index.php/Main_Page

  6. Defense Nanotechnology Research and Development Program

    National Research Council Canada - National Science Library

    2007-01-01

    ...), Army Research Office (ARO) and the Air Force Office of Scientific Research (AFOSR)initiated numerous research and development programs focusing on advancing science and technology below one micron in size...

  7. Rapid Development of Drilling Technology and Market of China

    Institute of Scientific and Technical Information of China (English)

    Wang Guanqing; Ni Rongfu

    1994-01-01

    @@ China's developing drilling market Now, CNPC is the owner of more than 1 000 rigs of large and medium size, including imported electric-drive rigs with 6 000 to 9 000 m drilling capacity, imported mechanical drive rigs with 5 000 to 6 000 m drilling capacity, imported mobile rigs with 1 500 to 3 000 m drilling capacity and a lot of home-made mechanical rigs with 2 000,3 200, 4 500 and 6 000m drilling capacity, which can meet the requirement of the domestic and foreign drilling market.

  8. Operational research leading to rapid national policy change: tuberculosis-diabetes collaboration in India.

    Science.gov (United States)

    Kumar, A M V; Satyanarayana, S; Wilson, N C; Chadha, S S; Gupta, D; Nair, S; Zachariah, R; Kapur, A; Harries, A D

    2014-06-21

    In 2011, bi-directional screening for tuberculosis (TB) and diabetes mellitus (DM) was recommended by the World Health Organization (WHO), although how best to implement the activity was not clear. In India, with early engagement of national programme managers and all important stakeholders, a countrywide, multicentre operational research (OR) project was designed in October 2011 and completed in 2012. The results led to a rapid national policy decision to routinely screen all TB patients for DM in September 2012. The process, experience and enablers of implementing this unique and successful collaborative model of operational research are presented.

  9. Infrastructure for Rapid Development of Java GUI Programs

    Science.gov (United States)

    Jones, Jeremy; Hostetter, Carl F.; Wheeler, Philip

    2006-01-01

    The Java Application Shell (JAS) is a software framework that accelerates the development of Java graphical-user-interface (GUI) application programs by enabling the reuse of common, proven GUI elements, as distinguished from writing custom code for GUI elements. JAS is a software infrastructure upon which Java interactive application programs and graphical user interfaces (GUIs) for those programs can be built as sets of plug-ins. JAS provides an application- programming interface that is extensible by application-specific plugins that describe and encapsulate both specifications of a GUI and application-specific functionality tied to the specified GUI elements. The desired GUI elements are specified in Extensible Markup Language (XML) descriptions instead of in compiled code. JAS reads and interprets these descriptions, then creates and configures a corresponding GUI from a standard set of generic, reusable GUI elements. These elements are then attached (again, according to the XML descriptions) to application-specific compiled code and scripts. An application program constructed by use of JAS as its core can be extended by writing new plug-ins and replacing existing plug-ins. Thus, JAS solves many problems that Java programmers generally solve anew for each project, thereby reducing development and testing time.

  10. Journal of Agricultural Research and Development

    African Journals Online (AJOL)

    The Journal of Agricultural Research and Development aims at publishing research reports, short communications, Critical Reviews in Agricultural Economics and Farm Management, Agronomy, Forestry, Animal Science, Food Technology, Soil Science, Home Economics, Agricultural Extension, Rural development, ...

  11. Publications | Page 11 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 101 - 110 of 6389 ... IDRC works with developing-country researchers and ... impact of our investment and advance development research. ... on a daily basis to her family in Huallhua, a tiny farming community in Peru's Andes Mountains.

  12. Advanced research reactor fuel development

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chang Kyu; Pak, H. D.; Kim, K. H. [and others

    2000-05-01

    The fabrication technology of the U{sub 3}Si fuel dispersed in aluminum for the localization of HANARO driver fuel has been launches. The increase of production yield of LEU metal, the establishment of measurement method of homogeneity, and electron beam welding process were performed. Irradiation test under normal operation condition, had been carried out and any clues of the fuel assembly breakdown was not detected. The 2nd test fuel assembly has been irradiated at HANARO reactor since 17th June 1999. The quality assurance system has been re-established and the eddy current test technique has been developed. The irradiation test for U{sub 3}Si{sub 2} dispersed fuels at HANARO reactor has been carried out in order to compare the in-pile performance of between the two types of U{sub 3}Si{sub 2} fuels, prepared by both the atomization and comminution processes. KAERI has also conducted all safety-related works such as the design and the fabrication of irradiation rig, the analysis of irradiation behavior, thermal hydraulic characteristics, stress analysis for irradiation rig, and thermal analysis fuel plate, for the mini-plate prepared by international research cooperation being irradiated safely at HANARO. Pressure drop test, vibration test and endurance test were performed. The characterization on powders of U-(5.4 {approx} 10 wt%) Mo alloy depending on Mo content prepared by rotating disk centrifugal atomization process was carried out in order to investigate the phase stability of the atomized U-Mo alloy system. The {gamma}-U phase stability and the thermal compatibility of atomized U-16at.%Mo and U-14at.%Mo-2at.%X(: Ru, Os) dispersion fuel meats at an elevated temperature have been investigated. The volume increases of U-Mo compatibility specimens were almost the same as or smaller than those of U{sub 3}Si{sub 2}. However the atomized alloy fuel exhibited a better irradiation performance than the comminuted alloy. The RERTR-3 irradiation test of nano

  13. Ethiopian Journal of Development Research: Advanced Search

    African Journals Online (AJOL)

    PROMOTING ACCESS TO AFRICAN RESEARCH ... Ethiopian Journal of Development Research: Advanced Search ... containing either term; e.g., education OR research; Use parentheses to create more complex queries; ... Ethiopian Journal of Business and Economics (The), Ethiopian Journal of Development Research ...

  14. Institutional research and development, FY 1987

    Energy Technology Data Exchange (ETDEWEB)

    Struble, G.L.; Lawler, G.M.; Crawford, R.B.; Kirvel, R.D.; Peck, T.M.; Prono, J.K.; Strack, B.S. (eds.)

    1987-01-01

    The Institutional Research and Development program at Lawrence Livermore National Laboratory fosters exploratory work to advance science and technology, disciplinary research to develop innovative solutions to problems in various scientific fields, and long-term interdisciplinary research in support of defense and energy missions. This annual report describes research funded under this program for FY87. (DWL)

  15. Institutional research and development, FY 1987

    International Nuclear Information System (INIS)

    Struble, G.L.; Lawler, G.M.; Crawford, R.B.; Kirvel, R.D.; Peck, T.M.; Prono, J.K.; Strack, B.S.

    1987-01-01

    The Institutional Research and Development program at Lawrence Livermore National Laboratory fosters exploratory work to advance science and technology, disciplinary research to develop innovative solutions to problems in various scientific fields, and long-term interdisciplinary research in support of defense and energy missions. This annual report describes research funded under this program for FY87

  16. Research and development and management of technology

    International Nuclear Information System (INIS)

    Kim, Yeong Gil

    1989-04-01

    This book mentions current state of affairs on research and development and prospect : activity of business, field like information and materials, energy and resource, public welfare, general industry technology. It introduces policy on promotion of research and development such as propel of special research and development business, propel strategy for 10 priority tasks, reinforcement of basic research, promotion of information industry and propel for technical development of business.

  17. Simple and rapid determination methods for low-level radioactive wastes generated from nuclear research facilities. Guidelines for determination of radioactive waste samples

    International Nuclear Information System (INIS)

    Kameo, Yutaka; Shimada, Asako; Ishimori, Ken-ichiro; Haraga, Tomoko; Katayama, Atsushi; Nakashima, Mikio; Hoshi, Akiko

    2009-10-01

    Analytical methods were developed for simple and rapid determination of U, Th, and several nuclides, which are selected as important nuclides for safety assessment of disposal of wastes generated from research facilities at Nuclear Science Research Institute and Oarai Research and Development Center. The present analytical methods were assumed to apply to solidified products made from miscellaneous wastes by plasma melting in the Advanced Volume Reduction Facilities. In order to establish a system to analyze the important nuclides in the solidified products at low cost and routinely, we have advanced the development of a high-efficiency non-destructive measurement technique for γ-ray emitting nuclides, simple and rapid methods for pretreatment of solidified product samples and subsequent radiochemical separations, and rapid determination methods for long-lived nuclides. In the present paper, we summarized the methods developed as guidelines for determination of radionuclides in the low-level solidified products. (author)

  18. Ethiopian Journal of Development Research

    African Journals Online (AJOL)

    This research investigated whether non-farm income diversification increases overall income equality and decreases poverty in rural Ethiopia or not. It used a four-wave panel data from the Ethiopian Rural Household Survey over the period 1994-2009. The impacts of non-farm income on inequality and poverty were ...

  19. Materials Processing Research and Development

    Science.gov (United States)

    2010-08-01

    2 2.1.4 The Origins of Microstexture in Duplex Ti Alloys...Controlled Growth and Coarsening ....... 14 2.11 PUBLISHED RESEARCH ON FRICTION STIR WELDING OF SC-MODIFIED AL-ZN-MG-CU EXTRUDED PLATES...14 2.11.1 Friction Stir Welding of Sc

  20. Cochrane Rapid Reviews Methods Group to play a leading role in guiding the production of informed high-quality, timely research evidence syntheses.

    Science.gov (United States)

    Garritty, Chantelle; Stevens, Adrienne; Gartlehner, Gerald; King, Valerie; Kamel, Chris

    2016-10-28

    Policymakers and healthcare stakeholders are increasingly seeking evidence to inform the policymaking process, and often use existing or commissioned systematic reviews to inform decisions. However, the methodologies that make systematic reviews authoritative take time, typically 1 to 2 years to complete. Outside the traditional SR timeline, "rapid reviews" have emerged as an efficient tool to get evidence to decision-makers more quickly. However, the use of rapid reviews does present challenges. To date, there has been limited published empirical information about this approach to compiling evidence. Thus, it remains a poorly understood and ill-defined set of diverse methodologies with various labels. In recent years, the need to further explore rapid review methods, characteristics, and their use has been recognized by a growing network of healthcare researchers, policymakers, and organizations, several with ties to Cochrane, which is recognized as representing an international gold standard for high-quality, systematic reviews. In this commentary, we introduce the newly established Cochrane Rapid Reviews Methods Group developed to play a leading role in guiding the production of rapid reviews given they are increasingly employed as a research synthesis tool to support timely evidence-informed decision-making. We discuss how the group was formed and outline the group's structure and remit. We also discuss the need to establish a more robust evidence base for rapid reviews in the published literature, and the importance of promoting registration of rapid review protocols in an effort to promote efficiency and transparency in research. As with standard systematic reviews, the core principles of evidence-based synthesis should apply to rapid reviews in order to minimize bias to the extent possible. The Cochrane Rapid Reviews Methods Group will serve to establish a network of rapid review stakeholders and provide a forum for discussion and training. By facilitating

  1. Development of a definition for Rapid Progression (RP) of renal function in HIV-positive persons

    DEFF Research Database (Denmark)

    Kamara, David A; Nielsen, Lene Ryom; Ross, Michael

    2014-01-01

    No consensus exists on how to define abnormally rapid deterioration in renal function (Rapid Progression, RP). We developed an operational definition of RP in HIV-positive persons with baseline estimated glomerular filtration rate (eGFR) >90ml/min/1.73m2 (using Cockcroft Gault) in the Data...

  2. Laboratory Directed Research and Development Program: FY 2015 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    SLAC,

    2016-04-04

    The Department of Energy (DOE) and the SLAC National Accelerator Laboratory (SLAC) encourage innovation, creativity, originality and quality to maintain the Laboratory’s research activities and staff at the forefront of science and technology. To further advance its scientific research capabilities, the Laboratory allocates a portion of its funds for the Laboratory Directed Research and Development (LDRD) program. With DOE guidance, the LDRD program enables SLAC scientists to make rapid and significant contributions that seed new strategies for solving important national science and technology problems. The LDRD program is conducted using existing research facilities.

  3. Biosensing International Research and Development

    CERN Document Server

    Schultz, Jerome; Mrksich, Milan

    2006-01-01

    The goal of this book is to disseminate information on the worldwide status and trends in biosensing R&D to government decisionmakers and the research community. The contributors critically analyze and compare biosensing research in the United States with that being pursued in Japan, Europe and other major industrialized countries. Biosensing includes systems that incorporate a variety of means, including electrical, electronic, and photonic devices; biological materials (e.g., tissue, enzymes, nucleic acids, etc.); and chemical analysis to produce detectable signals for the monitoring or identification of biological phenomena. In a broader sense, the study of biosensing includes any approach to detection of biological elements and the associated software or computer identification technologies (e.g., imaging) that identify biological characteristics. Biosensing is finding a growing number of applications in a wide variety of areas, including biomedicine, food production and processing, and detection of b...

  4. Research reactor developments in Australia

    International Nuclear Information System (INIS)

    Godfrey, Robert

    1998-01-01

    The Australian Nuclear Science and Technology Organization (ANSTO) operates the 10 MW research reactor, HIFAR, at the Lucas Heights site approximately 30 kilometres south of Sydney. Although recent reviews and inspections have confirmed that HIFAR operates safely by an adequate margin and has minimal impact, it was concluded that the reactor design and age places limitations on its operation and utilization, and that HIFAR is approaching the end of its economic life. In September 1997, a decision was made by the Australian Government to found ANSTO for the construction of a replacement research on the existing Lucas Heights site, subject to the requisite environmental assessment process. A draft EIS has been prepared and is currently undergoing public review. A design specification is in preparation, and a research reactor vendor pre-qualification process has been initiated. Spent fuel shipments have been made to Dounreay and to the Savannah River Site, and discussions are continuing regarding the disposition of the existing spent fuel and that arising form HIFAR's remaining operation. (author)

  5. Low Cost Rapid Response Spacecraft, (LCRRS): A Research Project in Low Cost Spacecraft Design and Fabrication in a Rapid Prototyping Environment

    Science.gov (United States)

    Spremo, Stevan; Bregman, Jesse; Dallara, Christopher D.; Ghassemieh, Shakib M.; Hanratty, James; Jackson, Evan; Kitts, Christopher; Klupar, Pete; Lindsay, Michael; Ignacio, Mas; hide

    2009-01-01

    The Low Cost Rapid Response Spacecraft (LCRRS) is an ongoing research development project at NASA Ames Research Center (ARC), Moffett Field, California. The prototype spacecraft, called Cost Optimized Test for Spacecraft Avionics and Technologies (COTSAT) is the first of what could potentially be a series of rapidly produced low-cost satellites. COTSAT has a target launch date of March 2009 on a SpaceX Falcon 9 launch vehicle. The LCRRS research system design incorporates use of COTS (Commercial Off The Shelf), MOTS (Modified Off The Shelf), and GOTS (Government Off The Shelf) hardware for a remote sensing satellite. The design concept was baselined to support a 0.5 meter Ritchey-Chretien telescope payload. This telescope and camera system is expected to achieve 1.5 meter/pixel resolution. The COTSAT team is investigating the possibility of building a fully functional spacecraft for $500,000 parts and $2,000,000 labor. Cost is dramatically reduced by using a sealed container, housing the bus and payload subsystems. Some electrical and RF designs were improved/upgraded from GeneSat-1 heritage systems. The project began in January 2007 and has yielded two functional test platforms. It is expected that a flight-qualified unit will be finished in December 2008. Flight quality controls are in place on the parts and materials used in this development with the aim of using them to finish a proto-flight satellite. For LEO missions the team is targeting a mission class requiring a minimum of six months lifetime or more. The system architecture incorporates several design features required by high reliability missions. This allows for a true skunk works environment to rapidly progress toward a flight design. Engineering and fabrication is primarily done in-house at NASA Ames with flight certifications on materials. The team currently employs seven Full Time Equivalent employees. The success of COTSATs small team in this effort can be attributed to highly cross trained

  6. Research and Development in ENSA

    International Nuclear Information System (INIS)

    2006-01-01

    We conceive R and D as a whole of creative works undertaken in a systematic way to increase our knowledge and conceive new applications for our productive processes. Advanced technology is developed and applied in ENSA by different departments. Coordination is done by the Technology Division. The development of new applications for the different metallurgical processes are mainly carried out by the Welding and Metallurgy Laboratories Development for process Automation and Robotization are carried out by the Automation department in close collaboration with the Welding, Engineering, Quality and Production departments, as appropriate. The upgrading of Machines and Installations is carried out by Engineering and Production. We believe in Innovation as an ongoing Strategy for our competitiveness. (Author)

  7. The Water-Energy-Food Nexus in a Rapidly Developing Resource Sector

    Science.gov (United States)

    Allen, D. M.; Kirste, D. M.

    2014-12-01

    Technological advances and access to global markets have changed the rate at which resource exploitation takes place. The environmental impact of the rapid development and distribution of resources such as minerals and hydrocarbons has led to a greater potential for significant stress on water resources both in terms of quality and quantity. How and where those impacts manifest is crucial to determining appropriate risk management strategies. North East British Columbia has an abundance of shale gas reserves that are anticipated to be exploited at a large scale in coming years, primarily for export as liquefied natural gas (LNG). However, there is growing concern that fracking and other activities related to shale gas development pose risks to water quality and quantity in the region. Water lies at the center of the water-energy-food nexus, with an accelerating water demand for fracking and industrial operations as well as for domestic, environmental and agricultural uses. Climate change is also anticipated to alter the hydrologic regime, posing added stress to the water resource. This case study examines the water-energy-food nexus in the context of a region that is impacted by a rapidly developing resource sector, encompassing water demand/supply, climate change, interaction between deep aquifers and shallow aquifers/surface waters, water quality concerns related to fracking, land use disturbance, and community impacts. Due to the rapid rate of development, there are significant knowledge gaps in our understanding of the water resource. Currently agencies are undertaking water resource assessments and establishing monitoring sites. This research aims to assess water security in North East British Columbia in a coordinated fashion through various partnerships. In addition to collecting baseline knowledge and data, the study will evaluate risk and resilience indicators in relation to water security. A risk assessment framework specific to the shale gas development

  8. IDRC - International Development Research Centre |

    International Development Research Centre (IDRC) Digital Library (Canada)

    Learn moreArtificial intelligence and human development ... Our experts share insights on the issues and approaches challenging the international ... Shadow Libraries: Access to Knowledge in Global Higher Education · Book cover: ... Social Theories of Urban Violence in the Global South: Towards Safe and Inclusive Cities.

  9. Late winter feeding stimulates rapid spring development of carniolan honey bee colonies (Apis mellifera carnica

    Directory of Open Access Journals (Sweden)

    Zlatko Puškadija

    2017-01-01

    Full Text Available Unfavourable weather conditions after the queen starts with intensive oviposition during early spring may cause an imbalance in the division of tasks among worker bees in the bee colony. This can lead to slow spring development and poor exploitation of the main spring nectar flows. In order to accelerate the spring development, it is necessary, as a technological measure, to feed supplemental candy to bee colonies. In this research, the necessity of supplemental feeding, as well as the composition of candy (pollen and protein substitute were analysed. Three groups of ten bee colonies each were formed - the control, unfed group, pollen candy fed and protein substitute candy fed. In the period from 22/02/2016 and 04/04/2016 three control measurements were performed during which the number of bees, the number of brood cells and weight of the bee colonies were determined. The research has shown that supplemental feeding of the bee colony in late winter in order to encourage the rapid spring development is justified. Namely, at the final measurements in April, the results showed differences between groups. The treated colonies had higher net hive weight, a greater number of bees and statistically significantly more brood cells. The results of this study confirm that the technological measure of supplemental feeding in late winter should be performed on all commercial apiaries for the production of honey, pollen, royal jelly, queen bees and bee venom.

  10. 2010-11 Research Portfolio: Research & Development Division

    Science.gov (United States)

    Educational Testing Service, 2010

    2010-01-01

    This document describes the breadth of the research that the ETS (Educational Testing Service) Research & Development division is conducting in 2010. This portfolio will be updated in early 2011 to reflect changes to existing projects and new projects that were added after this document was completed. The research described in this portfolio falls…

  11. State and Federal project development procedures for bus rapid transit : managing differences and reducing implementation delays

    Science.gov (United States)

    2011-08-01

    This report documents an investigation into the transportation project development process in the : context of the implementation of bus rapid transit systems on the State Highway System as well as such : systems being part of the Federal New Starts ...

  12. Energy storage research and development

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2008-01-01

    In 2007, US consumers experienced the highest sustained gasoline prices in recent history, in real terms, including those seen in the early 1980s1. Partially as a result of the $3/gallon gasoline prices, sales of hybrid electric vehicles (HEVs) increased almost 60% in 20072, and several automakers announced plans to develop plug-in hybrid electric vehicles (PHEVs)3. However, total sales of HEVs remained in the 2-3 percent range of all vehicle sales. An important step for continued HEV market penetration, as well as electrifying the nation's personal transportation, is the development of cost effective, long lasting, and abuse tolerant Li-ion batteries.

  13. Research and Development from the bottom up

    DEFF Research Database (Denmark)

    Brem, Alexander; Wolfram, P.

    2014-01-01

    and ecological context or the growing interest of developed market firms in approaches from emerging markets. Hence, the presented framework supports further research in new paradigms for research and development (R&D) in developed market firms (DMFs), particularly in relation to emerging markets. This framework...... enables scholars to compare concepts from developed and emerging markets, to address studies specifically by using consistent terms, and to advance research into the concepts according their characterization....

  14. Reusable launch vehicle development research

    Science.gov (United States)

    1995-01-01

    NASA has generated a program approach for a SSTO reusable launch vehicle technology (RLV) development which includes a follow-on to the Ballistic Missile Defense Organization's (BMDO) successful DC-X program, the DC-XA (Advanced). Also, a separate sub-scale flight demonstrator, designated the X-33, will be built and flight tested along with numerous ground based technologies programs. For this to be a successful effort, a balance between technical, schedule, and budgetary risks must be attained. The adoption of BMDO's 'fast track' management practices will be a key element in the eventual success of NASA's effort.

  15. Nigerian Educational Research For Sustainable Development ...

    African Journals Online (AJOL)

    Education and research controls the development of any nation because no nation can rise above the products of its educational system. However, a number of problems face our educational and national development in general. The solution to such problem lies in research . educational research for sustainable ...

  16. Publications | Page 87 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 861 - 870 of 6381 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. We share the ...

  17. Publications | Page 17 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 161 - 170 of 6379 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. We share the ...

  18. Publications | Page 22 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 211 - 220 of 2177 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. We share the ...

  19. Participatory Research and Development for Sustainable Agriculture ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    It is crucial, for example, that local stakeholders provide input to the process. Participatory research and ... Participatory Research and Development for Sustainable Agriculture and Natural Resource Management - A Sourcebook Volume 2: Enabling Participatory Research and Development. Book cover Participatory ...

  20. Publications | Page 4 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 31 - 40 of 6375 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. We share the ...

  1. Publications | Page 31 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 301 - 310 of 6388 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. We share the ...

  2. Publications | Page 36 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 351 - 360 of 6341 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. We share the ...

  3. Publications | Page 29 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 281 - 290 of 6341 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. We share the ...

  4. Publications | Page 85 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 841 - 850 of 6381 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. We share the ...

  5. Publications | Page 82 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 811 - 820 of 6372 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. We share the ...

  6. Publications | Page 56 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 551 - 560 of 6381 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. We share the ...

  7. View all initiatives | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The International Research Chairs Initiative pairs top research talent from universities in Canada with their counterparts in developing countries to address key development challenges. We fund researchers driving global change. Careers · Contact Us · Subscribe · Unsubscribe · Site map. Follow us; Facebook · Twitter ...

  8. Publications | Page 22 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 211 - 220 of 6379 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. We share the ...

  9. Publications | Page 26 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 251 - 260 of 6378 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. We share the ...

  10. Publications | Page 79 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 781 - 790 of 6372 ... Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. We share the results of our funded research, and offer free training materials to guide researchers and institutions. Want more? Explore outputs from more ...

  11. Research Skills Development in Higher Education Students

    Science.gov (United States)

    Bergamini, Tiziana Priede; Navarro, Cristina Lopez-Cozar

    2014-01-01

    This case study presents the development of a research project in a third-year undergraduate course, Family Business Administration. The research project aimed at promoting research skills in students. The authors formed working groups of no more than six students, and each group had to select an original research topic after conducting a…

  12. Research and Development Conference CIEE Program 1992

    Energy Technology Data Exchange (ETDEWEB)

    1992-11-01

    CIEE`s second annual Research and Development Conference will introduce you to some of the results achieved to date through CIEE-sponsored multiyear research performed in three programs: Building Energy Efficiency, Air Quality Impacts of Energy Efficiency, and End-Use Resource Planning. Results from scoping studies, Director`s discretionary research, and exploratory research will also be featured in this report.

  13. Key stakeholder perceptions about consent to participate in acute illness research: a rapid, systematic review to inform epi/pandemic research preparedness.

    Science.gov (United States)

    Gobat, Nina H; Gal, Micaela; Francis, Nick A; Hood, Kerenza; Watkins, Angela; Turner, Jill; Moore, Ronald; Webb, Steve A R; Butler, Christopher C; Nichol, Alistair

    2015-12-29

    A rigorous research response is required to inform clinical and public health decision-making during an epi/pandemic. However, the ethical conduct of such research, which often involves critically ill patients, may be complicated by the diminished capacity to consent and an imperative to initiate trial therapies within short time frames. Alternative approaches to taking prospective informed consent may therefore be used. We aimed to rapidly review evidence on key stakeholder (patients, their proxy decision-makers, clinicians and regulators) views concerning the acceptability of various approaches for obtaining consent relevant to pandemic-related acute illness research. We conducted a rapid evidence review, using the Internet, database and hand-searching for English language empirical publications from 1996 to 2014 on stakeholder opinions of consent models (prospective informed, third-party, deferred, or waived) used in acute illness research. We excluded research on consent to treatment, screening, or other such procedures, non-emergency research and secondary studies. Papers were categorised, and data summarised using narrative synthesis. We screened 689 citations, reviewed 104 full-text articles and included 52. Just one paper related specifically to pandemic research. In other emergency research contexts potential research participants, clinicians and research staff found third-party, deferred, and waived consent to be acceptable as a means to feasibly conduct such research. Acceptability to potential participants was motivated by altruism, trust in the medical community, and perceived value in medical research and decreased as the perceived risks associated with participation increased. Discrepancies were observed in the acceptability of the concept and application or experience of alternative consent models. Patients accepted clinicians acting as proxy-decision makers, with preference for two decision makers as invasiveness of interventions increased

  14. Publications | Page 25 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 241 - 250 of 6341 ... Journal articles. Papers. Reports. Research in Action. Studies ... Half a year later, on. ... Over the past two decades, the International Development Research Centre (IDRC) has established and subsequently devolved ...

  15. Participatory Research and Development for Sustainable Agriculture ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Participatory research and development (PR&D) offers such an inclusive model. ... PR&D concepts and practices for practitioners, researchers, and academic. ... Call for new OWSD Fellowships for Early Career Women Scientists now open.

  16. Publications | Page 21 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 201 - 210 of 6387 ... Through books, articles, research publications, and studies, we aim to widen the ... Development Research Centre (IDRC), the project uses evidence to enhance the ... Greening South America, one business at a time.

  17. Research and Development Information System (RDIS)

    Data.gov (United States)

    Department of Veterans Affairs — The Research and Development Information System (RDIS) is the Veterans Affairs Central Office budgetary and project data repository for managing the VA Research and...

  18. Publications | Page 62 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 611 - 620 of 6341 ... IDRC works with developing-country researchers and institutions to build ... America, and Australia and to determine knowledge gaps for future research. ... health and rights framework for population and health policy, ...

  19. Journal of Agricultural Research and Development

    African Journals Online (AJOL)

    The Journal of Agricultural Research and Development aims at publishing research reports, short communications, Critical Reviews in Agricultural Economics and Farm ... Response of Sesamum radiatum Schum vegetable and seed yield to ...

  20. Research Award: Innovation for Inclusive Development program

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC CRDI

    2011-09-12

    Sep 12, 2011 ... students, as well as recent graduates, to enhance their research skills ... experience in development research. ... enable greater understanding of how innovation in the informal ... Innovation and women in the informal sector.

  1. IPMC microgripper research and development

    International Nuclear Information System (INIS)

    Lumia, R; Shahinpoor, M

    2008-01-01

    Described are the state of the art on designing and developing a microgripper using ionic polymer metal composites (IPMCs), an electroactive material, as an actuator to grasp and manipulate micro-sized flexible and rigid objects and yet also serve as a sensor for position feedback control. IPMCs, as a material, are compliant and can work in both wet and dry environments. This makes it ideally suited for both industrial operations, e.g., building microsystems from MEMS components, as well as for a variety of bio-micromanipulation tasks, e.g., bacterium and cell handling. We derive a theoretical force model for the microgripper. The model estimates that an IPMC finger of dimensions 5mm x lmm x 0.2mm exerts a force of 85 μN when grasping a solder ball of 15mg. We experimentally measure the load carrying capacity of the IPMC microgripper. Furthermore, we show empirically that the relationship between load carry capability and the length of microgripper fingers is linear. Experiments with three different microgripper finger shapes show that load carrying performance is related to the area of the finger rather than the shape. This implies that manufacturing ease favours microgrippers with tapered fingers. Finally, we show how flexible objects (hydrogel crystals in this case) are grasped with this IPMC microgripper.

  2. Agricultural extension, research, and development for increased ...

    African Journals Online (AJOL)

    The challenges of food security and agricultural development in South Africa cannot simply be solved by limiting extension and research development to the public sector. However, if shortcomings arise in the public sector while addressing extension, research and development, the potential involvement of the private sector ...

  3. Anindya Chatterjee | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Dr Anindya Chatterjee is Regional Director, Asia, based in New Delhi, India. He has provided leadership in research, research management, policy, and program development in the area of global health and development. Dr Chatterjee formerly worked internationally with United Nations development agencies, and ...

  4. Development of a research evaluation protocol for NSD research portfolios

    International Nuclear Information System (INIS)

    Gould, J.

    1999-01-01

    This report is concerned with developing and describing a research evaluation protocol for use by the Nuclear Safety Directorate (NSD), in evaluating their various programmes of research; or aspects of those programmes. The Health and Safety Executive (HSE) has been involved with research evaluation for some considerable time and NSD, as part of HSE, wishes to develop a protocol which, while it meets their needs, is also fully compatible with other HSE approaches. It is intended that the methodology developed by this project will be used for evaluation of the Probabilistic Safety Assessment Portfolio (as a separate project). The usefulness of the methodology will be reviewed in the light of this experience

  5. Current research and development at the Nuclear Research Center Karlsruhe

    International Nuclear Information System (INIS)

    Kuesters, H.

    1982-01-01

    The Nuclear Research Center Karlsruhe (KfK) is funded to 90% by the Federal Republic of Germany and to 10% by the State of Baden-Wuerttemberg. Since its foundation in 1956 the main objective of the Center is research and development (R and D) in the aera of the nuclear technology and about 2/3 of the research capacity is now devoted to this field. Since 1960 a major activity of KfK is R and D work for the design of fast breeder reactors, including material research, physics, and safety investigations; a prototype of 300 MWe is under construction now in the lower Rhine Valley. For enrichment of 235 U fissile material KfK developed the separation nozzle process; its technical application is realized within an international contract between the Federal Republic of Germany and Brazil. Within the frame of the European Programme on fusion technology KfK develops and tests superconducting magnets for toroidal fusion systems; a smaller activity deals with research on inertial confinement fusion. A broad research programme is carried through for safety investigations of nuclear installations, especially for PWRs; this activity is supplemented by research and development in the field of nuclear materials' safeguards. Development of fast reactors has to initiate research for the reprocessing of spent fuel and waste disposal. In the pilot plant WAK spent fuel from LKWs is reprocessed; research especially tries e.g. to improve the PUREX-process by electrochemical means, vitrification of high active waste is another main activity. First studies are being performed now to clarify the necessary development for reprocessing fast reactor fuel. About 1/3 of the research capacity of KfK deals with fundamental research in nuclear physics, solid state physics, biology and studies on the impact of technology on environment. Promising new technologies as e.g. the replacement of gasoline by hydrogen cells as vehicle propulsion are investigated. (orig.)

  6. Mobility Research and Development (Briefing charts)

    Science.gov (United States)

    2016-03-17

    Mobility Research & Development Dr. Paramsothy Jayakumar, STE, Analytics Tank Automotive Research, Development and Engineering Center Research...Mobility Model (NRMM) • Dr. M. G. Bekker of TARDEC is the “Father of Terrain-Vehicle Systems ” • NRMM was developed in 1960-70 by TARDEC and ERDC...Blocks: Scaled Experiments Particle Image Velocimetry Pressure – Sinkage Test Direct Shear Test Simulations Single Wheel Test Plate width = 50 mm

  7. Health Systems Research in a Complex and Rapidly Changing Context: Ethical Implications of Major Health Systems Change at Scale.

    Science.gov (United States)

    MacGregor, Hayley; Bloom, Gerald

    2016-12-01

    This paper discusses health policy and systems research in complex and rapidly changing contexts. It focuses on ethical issues at stake for researchers working with government policy makers to provide evidence to inform major health systems change at scale, particularly when the dynamic nature of the context and ongoing challenges to the health system can result in unpredictable outcomes. We focus on situations where 'country ownership' of HSR is relatively well established and where there is significant involvement of local researchers and close ties and relationships with policy makers are often present. We frame our discussion around two country case studies with which we are familiar, namely China and South Africa and discuss the implications for conducting 'embedded' research. We suggest that reflexivity is an important concept for health system researchers who need to think carefully about positionality and their normative stance and to use such reflection to ensure that they can negotiate to retain autonomy, whilst also contributing evidence for health system change. A research process informed by the notion of reflexive practice and iterative learning will require a longitudinal review at key points in the research timeline. Such review should include the convening of a deliberative process and should involve a range of stakeholders, including those most likely to be affected by the intended and unintended consequences of change. © 2016 The Authors Developing World Bioethics Published by John Wiley & Sons Ltd.

  8. Cuba | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Researchers developed a way for community members to track mosquito ... government, and business, they bring concrete and innovative development ideas to ... areas such as maternal and child health, and sustainable water management.

  9. Rapid mental computation system as a tool for algorithmic thinking of elementary school students development

    OpenAIRE

    Ziatdinov, Rushan; Musa, Sajid

    2013-01-01

    In this paper, we describe the possibilities of using a rapid mental computation system in elementary education. The system consists of a number of readily memorized operations that allow one to perform arithmetic computations very quickly. These operations are actually simple algorithms which can develop or improve the algorithmic thinking of pupils. Using a rapid mental computation system allows forming the basis for the study of computer science in secondary school.

  10. Rapid Hip Osteoarthritis Development in a Patient with Anterior Acetabular Cyst with Sagittal Alignment Change

    Directory of Open Access Journals (Sweden)

    Yasuhiro Homma

    2014-01-01

    Full Text Available Rapidly destructive coxarthrosis (RDC is rare and develops unusual clinical course. Recent studies suggest multiple possible mechanisms of the development of RDC. However the exact mechanism of RDC is still not clear. The difficulty of the study on RDC is attributed to its rareness and the fact that the data before the onset of RDC is normally unavailable. In this report, we presented the patient having the radiographic data before the onset who had rapid osteoarthritis (OA development after contralateral THA, which meets the current criteria of RDC. We thought that the increased posterior tilt of the pelvis after THA reinforced the stress concentration at pre-existed anterior acetabular cyst, thereby the destruction of the cyst was occurred. As a result the rapid OA was developed. We think that there is the case of rapid osteoarthritis developing due to alternating load concentration by posterior pelvic tilt on preexisting anterior acetabular cyst such as our patient among the cases diagnosed as RDC without any identifiable etiology. The recognition of sagittal alignment changes and anterior acetabular cyst may play important role in prediction and prevention of the rapid hip osteoarthritis development similar to RDC.

  11. Publications | Page 42 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 411 - 420 of 6382 ... Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. We share the results of our funded ... Evaluation in the Extreme: Research, Impact and Politics in Violently Divided Societies. Over the past two decades, ...

  12. Publications | Page 76 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 751 - 760 of 6335 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. Through books, articles, research ... Caribbean health : diversity in local food production to combat obesity (restricted access). Led by researchers from McGill ...

  13. Gender | Page 230 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    For research results to improve people's lives, they must reach decision-makers who can use them to develop more effective policies and practices. About 20% of IDRC's project funding in the past year — and the past decade — went to research that aimed to influence policies. To help IDRC-supported research results ...

  14. Managing Research Libraries in Developing Economy | Ahmed ...

    African Journals Online (AJOL)

    This paper discusses managing research libraries in developing economy. The concepts of special libraries, funding of research libraries, the need for training and retraining of library staff and resources sharing networking were highlighted. The paper recommends that research Institutes need to re-order their priorities ...

  15. Development of materials for the rapid manufacture of die cast tooling

    Science.gov (United States)

    Hardro, Peter Jason

    The focus of this research is to develop a material composition that can be processed by rapid prototyping (RP) in order to produce tooling for the die casting process. Where these rapidly produced tools will be superior to traditional tooling production methods by offering one or more of the following advantages: reduced tooling cost, shortened tooling creation time, reduced man-hours for tool creation, increased tool life, and shortened die casting cycle time. By utilizing RP's additive build process and vast material selection, there was a prospect that die cast tooling may be produced quicker and with superior material properties. To this end, the material properties that influence die life and cycle time were determined, and a list of materials that fulfill these "optimal" properties were highlighted. Physical testing was conducted in order to grade the processability of each of the material systems and to optimize the manufacturing process for the downselected material system. Sample specimens were produced and microscopy techniques were utilized to determine a number of physical properties of the material system. Additionally, a benchmark geometry was selected and die casting dies were produced from traditional tool materials (H13 steel) and techniques (machining) and from the newly developed materials and RP techniques (selective laser sintering (SLS) and laser engineered net shaping (LENS)). Once the tools were created, a die cast alloy was selected and a preset number of parts were shot into each tool. During tool creation, the manufacturing time and cost was closely monitored and an economic model was developed to compare traditional tooling to RP tooling. This model allows one to determine, in the early design stages, when it is advantageous to implement RP tooling and when traditional tooling would be best. The results of the physical testing and economic analysis has shown that RP tooling is able to achieve a number of the research objectives, namely

  16. Research in Review. Malnutrition and Children's Development.

    Science.gov (United States)

    Stevens, Joseph H., Jr.; Baxter, Delia H.

    1981-01-01

    Indicates how various degrees of malnutrition affect children's development. Reviews research conducted in several developing countries and the United States, and describes the nutritional status of children in the United States. Implications for nutrition programs, research and policy formation are pointed out. (Author/RH)

  17. Program Leader | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Leads in the identification of the overall development research ... Ensures that a regional perspective is brought to bear on program planning at the PI and ... The incumbent is the manager of the Program Initiative program and team and as such: ... projects between Canadian and developing country researchers; and; When ...

  18. Publications | Page 50 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 491 - 500 of 6341 ... Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. ... ​Does the unequal distribution of technological resources and available data sets threaten the developing world's participation in the open data ...

  19. Metal-air battery research and development

    Science.gov (United States)

    Behrin, E.; Cooper, J. F.

    1982-05-01

    This report summarizes the activities of the Metal-air Battery Program during the calendar year 1981. The principal objective is to develop a refuelable battery as an automotive energy source for general-purpose electric vehicles and to conduct engineering demonstrations of its ability to provide vehicles with the range, acceleration, and rapid refueling capability of current internal-combustion-engine automobiles. The second objective is to develop an electrically-rechargeable battery for specific-mission electric vehicles, such as commuter vehicles, that can provide low-cost transportation. The development progression is to: (1) develop a mechanically rechargeable aluminum-air power cell using model electrodes, (2) develop cost-effective anode and cathode materials and structures as required to achieve reliability and efficiency goals, and to establish the economic competitiveness of this technology, and (3) develop and integrated propulsion system utilizing the power cell.

  20. Plan and procedures for rapid inventory taking at the Research Institute for Atomic Reactors

    International Nuclear Information System (INIS)

    Kalygin, V.; Gorobets, A.; Karlov, S.; Suda, S.C.; Bonner, M.F.; Satkowiak, L.

    1997-01-01

    A major element of a system for nuclear material protection, control, and accounting (MPC and A) is to take the physical inventory of the nuclear material periodically. Physical inventory taking (PIT) includes ensuring that all nuclear material on inventory is included in the facility records and that the measured content of items or containers corresponds to the recorded values. A preliminary step to the conduct of the PIT is application of rapid inventory procedures that serve to provide the benchmark for the inventory, e.g., by identifying if any items are missing and also, if any unrecorded items are present. The Rapid Inventory approach is being implemented by the Research Institute for Atomic Reactors (RIAR) in Dimitrovgrad, Russia, as one of the first steps in the program to enhance nuclear materials safeguards at the site. This effort is being conducted under the US-Russian Cooperative Program on Nuclear Materials Protection. Control And Accounting (MPC and A), with assistance provided by specialists from US Department of Energy National Laboratories. This paper summarizes the features of the existing physical inventory system at RIAR, discusses the upgrades being introduced, and provides some observations on the technology transfer process with regard to the safeguards program

  1. Plan and procedures for rapid inventory taking at the research institute for atomic reactors

    International Nuclear Information System (INIS)

    Kalygin, V.; Gorobets, A.; Karlov, S.; Suda, S.C.; Bonner, F.M.

    1999-01-01

    A major element of a system for nuclear material protection, control, and accounting (MPC and A) is to take the physical inventory of the nuclear material periodically. Physical inventory taking (PIT) includes ensuring that all nuclear material on inventory is included in the facility records and that the measured content of items or containers (or at least a suitable random sample thereof) corresponds to the recorded values. A preliminary step to the conduct of the PIT is application of rapid inventory procedures that serve to provide the benchmark for the inventory, e.g., by identifying if any items are missing and also, if any unrecorded items are present. The Rapid Inventory approach is being implemented by the Research Institute for Atomic Reactors (RIAR) in Dimitrovgrad, Russia, as one of the first steps in the program to enhance nuclear materials safeguards at the site. This effort is being conducted under the US-Russian Cooperative Program on Nuclear Materials Protection, Control And Accounting (MPC and A), with assistance provided by specialists from U.S. Department of Energy National Laboratories. This paper summarizes the features of the existing physical inventory system at RIAR, discusses the upgrades being introduced, and provides some observations on the technology transfer process with regard to the safeguards program. (author)

  2. Sustainable energy for the future. Modelling transitions to renewable and clean energy in rapidly developing countries.

    NARCIS (Netherlands)

    Urban, Frauke

    2009-01-01

    The main objective of this thesis is first to adapt energy models for the use in developing countries and second to model sustainable energy transitions and their effects in rapidly developing countries like China and India. The focus of this thesis is three-fold: a) to elaborate the differences

  3. NATO Advanced Research Workshop, 19-22 May 1997: Rapid Method for Monitoring the Environment for Biological Hazards

    National Research Council Canada - National Science Library

    1997-01-01

    The NATO Advanced Research Workshop met for the purpose of bringing to light rapid methods for monitoring the environment for biological hazards such as biological warfare agents, naturally occurring...

  4. Research and Development Conference CIEE Program 1992

    Energy Technology Data Exchange (ETDEWEB)

    1992-01-01

    CIEE's second annual Research and Development Conference will introduce you to some of the results achieved to date through CIEE-sponsored multiyear research performed in three programs: Building Energy Efficiency, Air Quality Impacts of Energy Efficiency, and End-Use Resource Planning. Results from scoping studies, Director's discretionary research, and exploratory research will also be featured in this report.

  5. Development of polymer nano composite patterns using fused deposition modeling for rapid investment casting process

    Science.gov (United States)

    Vivek, Tiwary; Arunkumar, P.; Deshpande, A. S.; Vinayak, Malik; Kulkarni, R. M.; Asif, Angadi

    2018-04-01

    Conventional investment casting is one of the oldest and most economical manufacturing techniques to produce intricate and complex part geometries. However, investment casting is considered economical only if the volume of production is large. Design iterations and design optimisations in this technique proves to be very costly due to time and tooling cost for making dies for producing wax patterns. However, with the advent of Additive manufacturing technology, plastic patterns promise a very good potential to replace the wax patterns. This approach can be very useful for low volume production & lab requirements, since the cost and time required to incorporate the changes in the design is very low. This research paper discusses the steps involved for developing polymer nanocomposite filaments and checking its suitability for investment castings. The process parameters of the 3D printer machine are also optimized using the DOE technique to obtain mechanically stronger plastic patterns. The study is done to develop a framework for rapid investment casting for lab as well as industrial requirements.

  6. Considerations for Task Analysis Methods and Rapid E-Learning Development Techniques

    Directory of Open Access Journals (Sweden)

    Dr. Ismail Ipek

    2014-02-01

    Full Text Available The purpose of this paper is to provide basic dimensions for rapid training development in e-learning courses in education and business. Principally, it starts with defining task analysis and how to select tasks for analysis and task analysis methods for instructional design. To do this, first, learning and instructional technologies as visions of the future were discussed. Second, the importance of task analysis methods in rapid e-learning was considered, with learning technologies as asynchronous and synchronous e-learning development. Finally, rapid instructional design concepts and e-learning design strategies were defined and clarified with examples, that is, all steps for effective task analysis and rapid training development techniques based on learning and instructional design approaches were discussed, such as m-learning and other delivery systems. As a result, the concept of task analysis, rapid e-learning development strategies and the essentials of online course design were discussed, alongside learner interface design features for learners and designers.

  7. Research on rapid agile metrology for manufacturing based on real-time multitask operating system

    Science.gov (United States)

    Chen, Jihong; Song, Zhen; Yang, Daoshan; Zhou, Ji; Buckley, Shawn

    1996-10-01

    Rapid agile metrology for manufacturing (RAMM) using multiple non-contact sensors is likely to remain a growing trend in manufacturing. High speed inspecting systems for manufacturing is characterized by multitasks implemented in parallel and real-time events which occur simultaneously. In this paper, we introduce a real-time operating system into RAMM research. A general task model of a class-based object- oriented technology is proposed. A general multitask frame of a typical RAMM system using OPNet is discussed. Finally, an application example of a machine which inspects parts held on a carrier strip is described. With RTOS and OPNet, this machine can measure two dimensions of the contacts at 300 parts/second.

  8. Partnership in Knowledge Creation: Lessons Learned from a Researcher-Policy Actor Partnership to Co-Produce a Rapid Appraisal Case Study of South Australia's Social Inclusion Initiative

    Science.gov (United States)

    Newman, Lareen; Biedrzycki, Kate; Patterson, Jan; Baum, Fran

    2011-01-01

    This paper describes a partnership between researchers and policy actors that was developed within a short timeframe to produce a rapid appraisal case study of a government policy initiative--South Australia's "Social Inclusion Initiative"--for the Social Exclusion Knowledge Network of the international Commission on Social Determinants…

  9. New Product Development and Business Strategy of Research and Development

    International Nuclear Information System (INIS)

    Lee, Sun Cheol

    1998-05-01

    The contents of this book are new product development strategy of the top business, commercialization and new product development, development case analysis and framework of new product development, investigation strategy for idea of new product development, case analysis of research as development and goal of new product development, case analysis and planning and management for new product development, innovative item development and technical management against confusion, the map for determination procedure of development, strategy of market and goods and development strategy cases in leading company.

  10. Population Aging: An Emerging Research Agenda for Sustainable Development

    Directory of Open Access Journals (Sweden)

    Shogo Kudo

    2015-10-01

    Full Text Available In recent years, population aging has been recognized as an emerging challenge in many parts of the world. Earlier studies discussed its impacts on the sustainability of social security systems and national economic growth; however, they tended to focus on the issues at the national level and were limited to developed countries. With the knowledge that population aging will be a predominant trend in both developed and developing countries, this paper aims to: (i describe the global population aging trend and its regional demography; (ii provide a structural review of population aging challenges at the national, communal and individual levels; and (iii elaborate future research topics on population aging with a particular emphasis on developing countries. Several indicators suggest rapid population aging in the coming decades, especially in Asia, Latin America and Africa. The structural review presents the diverse challenges that affect both young and older population groups. Finally, the need for linking population aging with the sustainable development concept and the possible rural decline caused by rapid urbanization are suggested as future research topics. Further studies to establish a body of knowledge on population aging in developing countries are required to place population aging on the agenda of future sustainable development discussions.

  11. Peter Taylor | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    He leads a multidisciplinary team that strengthens policy research capacity in developing countries on issues of economic policy, governance, and health systems. Peter has more than 30 years of experience in international development, including positions at the Institute of Development Studies, UK; Helvetas Vietnam; ...

  12. View all initiatives | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The Open Data for Development program's global network will facilitate and scale innovative approaches to open data to ensure benefits reach citizens in developing countries. Combining research and action to address scaling and sustainability of open data for development initiatives is key to the network's success.

  13. Software Development as Music Education Research

    Science.gov (United States)

    Brown, Andrew R.

    2007-01-01

    This paper discusses how software development can be used as a method for music education research. It explains how software development can externalize ideas, stimulate action and reflection, and provide evidence to support the educative value of new software-based experiences. Parallels between the interactive software development process and…

  14. Development of computational small animal models and their applications in preclinical imaging and therapy research

    NARCIS (Netherlands)

    Xie, Tianwu; Zaidi, Habib

    The development of multimodality preclinical imaging techniques and the rapid growth of realistic computer simulation tools have promoted the construction and application of computational laboratory animal models in preclinical research. Since the early 1990s, over 120 realistic computational animal

  15. Development and clinical evaluation of a rapid diagnostic kit for feline leukemia virus infection.

    Science.gov (United States)

    Kim, Won-Shik; Chong, Chom-Kyu; Kim, Hak-Yong; Lee, Gyu-Cheol; Jeong, Wooseog; An, Dong-Jun; Jeoung, Hye-Young; Lee, Jae-In; Lee, Young-Ki

    2014-01-01

    Feline leukemia virus (FeLV) causes a range of neoplastic and degenerative diseases in cats. To obtain a more sensitive and convenient diagnosis of the disease, we prepared monoclonal antibodies specific for the FeLV p27 to develop a rapid diagnostic test with enhanced sensitivity and specificity. Among these antibodies, we identified two clones (hybridomas 8F8B5 and 8G7D1) that specifically bound to FeLV and were very suitable for a diagnostic kit. The affinity constants for 8F8B5 and 8G7D1 were 0.35 × 10⁸ and 0.86 × 10⁸, respectively. To investigate the diagnostic abilities of the rapid kit using these antibodies, we performed several clinical studies. Assessment of analytical sensitivity revealed that the detection threshold of the rapid diagnostic test was 2 ng/mL for recombinant p27 and 12.5 × 10⁴ IU/mL for FeLV. When evaluating 252 cat sera samples, the kit was found to have a kappa value of 0.88 compared to polymerase chain reaction (PCR), indicating a significant correlation between data from the rapid diagnostic test and PCR. Sensitivity and specificity of the kit were 95.2% (20/21) and 98.5% (257/261), respectively. Our results demonstrated that the rapid diagnostic test would be a suitable diagnostic tool for the rapid detection of FeLV infection in cats.

  16. Selection of the best security controls for rapid development of enterprise-level cyber security

    OpenAIRE

    Tytarenko, Oleksandr

    2017-01-01

    Approved for public release; distribution is unlimited State-supported cyber attacks, cyber espionage campaigns, and hacktivist movements have forced many states to accelerate their cyber defense development in order to achieve at least a minimum level of protection against expanding threats of cyber space. As with any other development effort, cyber capability development requires resources of time, money, and people, which in most cases are very restricted. To rapidly build up the first ...

  17. Research and Development Costs in Retail Trade

    Directory of Open Access Journals (Sweden)

    Radojko LUKIC

    2016-12-01

    Full Text Available Research and development expenses are crucial business performance factors for all enterprises, including trading companies. The size and structure of these expenses depend largely on the nature of a company’s activities. Due to such importance and specificity, the research focus of this article is on R&D expenses in trading companies with particular emphasis on retail companies. Their share in the sales revenue of trading companies is increasingly important and determined by many factors, such as innovation, size, location, product categories, and others. Due to varying intensity of influence of these and other factors, research and development expenses in commercial companies differ among countries, trade types (wholesale, retail, wholesale and retail, retail formats (store types and product categories. Understanding the factors of these differences is important for efficient management of research and development costs in trade, particularly retail companies. They are the focus of research in this work.

  18. Laos | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    As a result, local university researchers studied the effects of a new protected forest ... city of Luang Prabang, which introduced Internet services to rural people. ... the Government of Laos improve trade negotiations; leaders develop sound ...

  19. Publications | Page 75 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 741 - 750 of 6346 ... IDRC works with developing-country researchers and institutions to ... Improving the Nutrition and Health of CARICOM Populations : final ... policy and an unfavorable legal and regulatory environment, which in turn ...

  20. Publications | Page 28 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 271 - 280 of 6341 ... IDRC works with developing-country researchers and ... food and nutrition security for low- and middle-income households in Kenya and Uganda. ... of the work IDRC's Rural Poverty and Environment program has ...

  1. Gender | Page 229 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    . ... Building Businesses with Small Producers présente les constatations et une analyse ... Researchers identified the regions in Southeast Asia most vulnerable to ... asked why some children in developing countries are not being vaccinated.

  2. Guatemala | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Our early work in Guatemala targeted farming efficiency, access to water, ... Researchers also developed a low-cost coffee drying machine powered by coffee ... National Campaign for Inter-ethnic Dialogue, a public education campaign that ...

  3. Publications | Page 6 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 51 - 60 of 7327 ... IDRC works with developing-country researchers and institutions to build local ... Mobile phones, Internet, and gender in Myanmar ... India believe music can offer clues about the ability of the brain to transfer learning.

  4. Problems of scientific research in developing countries

    International Nuclear Information System (INIS)

    Vose, P.B.; Cervellini, A.

    1983-01-01

    The paper gives a general consideration of the problems encountered in the scientific research by the developing countries. Possible optimizations in the long term as well as short term strategies are pointed out

  5. Bolivia | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... systems, mining policies, natural resource management, labour force development, waste management, and land use reforms. ... Total IDRC Support ... stimulate high-quality, policy-relevant research by Bolivians; test climate change ...

  6. Publications | Page 9 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 81 - 90 of 6389 ... Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development ... Journal articles ... Forging a brighter future for Haiti through higher education.

  7. Agricultural biotechnology research and development in Ethiopia

    African Journals Online (AJOL)

    PRECIOUS

    2009-12-29

    Dec 29, 2009 ... Review. Agricultural biotechnology research and development in Ethiopia ... seed micropropagation, virus-cleaning ongoing, good progress. Garlic meristem ... large quantities of disease-free planting materials in short time.

  8. Cambodia | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... the National Information Communications Technology Development Authority. ... The research helped people improve their livelihoods, set limits on resource use, ... A national non-governmental organization called The Learning Institute, ...

  9. Thailand | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    In 1994, we helped create the Asian Development Research Forum, based at the ... topics as pensions, health care, migration, and women's role in family care. ... improve flood management planning to counteract climate change disasters, ...

  10. President | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    International Development Research Centre Selection Criteria Education A ... or an acceptable combination of education, job-related training and/or experience. ... Knowledge of current corporate governance and human resource issues; ...

  11. IDRC Research Awards 2019 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Citizens of developing countries pursuing a master's or a doctoral degree at a ... and will receive hands-on experience in research and program management and ... dissemination, and use of knowledge from an international perspective.

  12. Gender | Page 208 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC's mission is to support developing-country scientists in conducting applied, community-based research on ... Improve resource management, improve human health ... A new perspective on the links between health and ecosystems.

  13. View all initiatives | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The International Partnerships for Sustainable Societies are collaborations that produce high-quality research to inform academic, public, and policy debates to contribute to create just, inclusive, and sustainable social and economic development.

  14. Vital statistics | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    2011-07-13

    Jul 13, 2011 ... Population and Health in Developing Countries: Vol 1. ... We track down all those movements," says Dr Pierre Ngom, a senior research ... was recognized for its efforts to improve health service provision and the monitoring of ...

  15. David M. Malone President, International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    malonedm

    independent research and policy development institution in New York. From 1994 to 1998 ... His widely reviewed book The International Struggle Over Iraq: Politics in the ... also to write in a lighter vein, often for the Literary Review of Canada.

  16. Magnetic fusion research in developing countries

    International Nuclear Information System (INIS)

    Hassan, M.H.A.

    1990-01-01

    This article is a presentation prepared by the Third World Academy of Sciences on magnetic fusion research activity in the developing countries and its connection with the IAEA's own fusion programme. 6 figs, 1 tab

  17. Center for Cold Spray Research and Development

    Data.gov (United States)

    Federal Laboratory Consortium — This is the only DoD facility capable of cold spray research and development, production, and field-repair. It features three stationary cold spray systems used for...

  18. Publications | Page 62 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 611 - 620 of 6389 ... IDRC works with developing-country researchers and institutions to ... sp. strain UCD-UG_FMILLET was isolated from the roots of the Afro-. ... and men that perpetuate gender and inequality and power imbalances.

  19. Bulletin #111 | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Turning value chains into social gains in SE Asia: IDRC starts new work in ASEAN ... and promote youth development by enhancing community-based social capital. ... BUILDING AND EVALUATING RESEARCH CAPACITY IN HEALTHCARE ...

  20. Federal Support for Research and Development

    National Research Council Canada - National Science Library

    Campbell, Sheila

    2007-01-01

    ...-being. Private businesses are the largest sponsors of research and development (R&D) in the United States, producing the discoveries that in turn lead to new products and services and the growth of productivity...

  1. Using Architectures for Research, Development, and Acquisition

    National Research Council Canada - National Science Library

    Dickerson, C

    2004-01-01

    The goal of this book is to show how architectures can be used to enable a capabilities-based approach to the research, development, and acquisition of DoD families of systems that must interoperate...

  2. [Research on rapid and quantitative detection method for organophosphorus pesticide residue].

    Science.gov (United States)

    Sun, Yuan-Xin; Chen, Bing-Tai; Yi, Sen; Sun, Ming

    2014-05-01

    The methods of physical-chemical inspection is adopted in the traditional pesticide residue detection, which require a lot of pretreatment processes, are time-consuming and complicated. In the present study, the authors take chlorpyrifos applied widely in the present agricultural field as the research object and propose a rapid and quantitative detection method for organophosphorus pesticide residues. At first, according to the chemical characteristics of chlorpyrifos and comprehensive chromogenic effect of several colorimetric reagents and secondary pollution, the pretreatment of the scheme of chromogenic reaction of chlorpyrifos with resorcin in a weak alkaline environment was determined. Secondly, by analyzing Uv-Vis spectrum data of chlorpyrifos samples whose content were between 0. 5 and 400 mg kg-1, it was confirmed that the characteristic information after the color reaction mainly was concentrated among 360 approximately 400 nm. Thirdly, the full spectrum forecasting model was established based on the partial least squares, whose correlation coefficient of calibration was 0. 999 6, correlation coefficient of prediction reached 0. 995 6, standard deviation of calibration (RMSEC) was 2. 814 7 mg kg-1, and standard deviation of verification (RMSEP) was 8. 012 4 mg kg-1. Fourthly, the wavelengths whose center wavelength is 400 nm was extracted as characteristic region to build a forecasting model, whose correlation coefficient of calibration was 0. 999 6, correlation coefficient of prediction reached 0. 999 3, standard deviation of calibration (RMSEC) was 2. 566 7 mg kg-1 , standard deviation of verification (RMSEP) was 4. 886 6 mg kg-1, respectively. At last, by analyzing the near infrared spectrum data of chlorpyrifos samples with contents between 0. 5 and 16 mg kg-1, the authors found that although the characteristics of the chromogenic functional group are not obvious, the change of absorption peaks of resorcin itself in the neighborhood of 5 200 cm

  3. Publications | Page 56 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 551 - 560 of 6372 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. Through books, articles, research publications, ... The private sector, non-governmental organisations, government... Fisheries, aquaculture and living well in ...

  4. Publications | Page 39 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 381 - 390 of 6341 ... IDRC works with developing-country researchers and ... Through books, articles, research publications, and studies, we aim to ... Fish Farmers' Utilization of Social Networks in Adapting to ... City profile : Guwahati (restricted access) ... Nigeria : a case study of the Amnesty Programme (open access).

  5. Research and professional development of teacher educators

    NARCIS (Netherlands)

    Lunenberg, Mieke; Willemse, Martijn

    2006-01-01

    Over the last decade teacher educators have started to systematically study the processes involved in their efforts to improve their teacher education practices. This research by teacher educators (self-study research) has made an enormous contribution to the professional development of the teacher

  6. Global Affairs Canada | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    For example, Vietnamese and Canadian research teams developed micronutrient-enriched instant flours and baby cereals using local crops and local processing facilities. Global Affairs Canada, IDRC, and the Canadian Institutes of Health Research are collaborating to improve health outcomes for African mothers and ...

  7. Development research in South Africa | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2011-01-11

    Jan 11, 2011 ... IDRC Communications ... It would result, some three years later, in a program of development research support designed expressly to prepare ... In South Africa, post-secondary education is a privilege, and many students currently enrol ... Recent research into decision-making in households has produced ...

  8. The AECL research and development program

    International Nuclear Information System (INIS)

    Hart, R.G.; Woods, A.D.B.

    1980-02-01

    The research and development program of the Atomic Energy of Canada Research Company is briefly described. Goals and objectives are emphasized, some recent highlights are given and the importance of technology transfer is discussed. A short representative bibliography is included. (auth)

  9. Publications | Page 14 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 131 - 140 of 6379 ... This series of case studies emerged from an action-research project entitled Developing Evaluation and Communication Capacity in Information Society Research (DECI-2). The predecessor DECI-1 project focused only on evaluation mentoring in Asia. The subsequent DECI-2 project collaborated ...

  10. Publications | Page 79 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 781 - 790 of 6341 ... We share the results of our funded research, and offer free ... Through books, articles, research publications, and studies, we aim to widen the impact of ... Tourism is an important driver of economic growth throughout Southeast Asia. Inclusive development in health and education in the GMS : the ...

  11. View all initiatives | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The Science Granting Councils Initiative in Sub-Saharan Africa is focused on strengthening the capacities of science granting councils in order to support research and evidence-based policies that will contribute to economic and social development in Sub-Saharan Africa. We fund researchers driving global change.

  12. Present status of HTGR research and development

    International Nuclear Information System (INIS)

    1992-08-01

    This report briefly describes the progress of the construction of the High Temperature Engineering Test Reactor (HTTR), Research and Development (R and D) on the advanced technologies for the High Temperature Gas-cooled Reactors (HTGRs) and international cooperation in the Japan Atomic Energy Research Institute (JAERI) in 1991. (J.P.N.)

  13. Developing Research Skills across the Undergraduate Curriculum

    Science.gov (United States)

    Gray, Simon; Coates, Lee; Fraser, Ann; Pierce, Pam

    2015-01-01

    This chapter describes consortial efforts within the Great Lakes Colleges Association to share expertise and programming to build research skills throughout the undergraduate curriculum. Strategies to scaffold research skill development are provided from Allegheny College, Kalamazoo College, and The College of Wooster.

  14. Cambodia Development Research Forum II | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cambodia's research community is still rebuilding from decades of turmoil that included civil war and a period of ethnic and intellectual cleansing under the Khmer Rouge. Its development research community remains dispersed and unconnected, though there are pockets of strong capacity. IDRC was one of the first ...

  15. Agricultural biotechnology research and development in Ethiopia ...

    African Journals Online (AJOL)

    Ethiopia is an agrarian country that can have enormous benefit from the applications of biotechnology for increasing its agricultural productivity. The country is at initial stages of research and development in agricultural biotechnology with scattered efforts underway in various public institutions. Research efforts and ...

  16. Publications | Page 86 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 851 - 860 of 6372 ... Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. ... Global pathways to men's caregiving: mixed methods findings from the international men and gender equality survey and the men who care study ...

  17. Publications | Page 8 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 71 - 80 of 6341 ... Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. ... Brazil, metal waste and mud flowed downstream, contaminating the water and wreaking havoc as the worst environmental disaster in the nation's history.

  18. Nepal | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Plant breeding research in the 1980s and 1990s led to more productive cereals, such as finger millet and barley. Other efforts have strengthened farmers' ability to conserve the genetic diversity of their traditional crops. An improved rice variety — developed collaboratively by farmers and researchers — was introduced in ...

  19. Gender | Page 227 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Language English ... In a 12-country study, researchers asked why some children in developing countries are not being vaccinated. ... About 20% of IDRC's project funding in the past year — and the past decade — went to research that aimed ...

  20. Canada | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    While working with some of the brightest minds in Canada and the world, we've found that knowledge-sharing through networks and regions helps widen the impact of the research we fund. It is through the interaction of ideas, people, and money in worldwide development research and policy that we put our principles into ...

  1. US Army Medical Research and Development Report.

    Science.gov (United States)

    1979-10-01

    RI) US ARMY MEDICAL RESEARCH AND DEVELOPMENT REPORT. Colonel/John Jr DTIC JUL 1 5 1980; A USL &MY MEDICAL BIOENGINEERING RESEARCH AND DEVELOPMENT...pollutants in water or soil . Pollutant by-products and breakdown products in water, air or soil will be isolated, characterized, and quantified. Where...determination of selected low-level pollutants io soil and water. Degradation products and secondary pollutants arising from munitions manufacture or pest

  2. Is Mixed Methods Research Used in Australian Career Development Research?

    Science.gov (United States)

    Cameron, Roslyn

    2010-01-01

    Mixed methods research has become a substantive and growing methodological force that is growing in popularity within the human and social sciences. This article reports the findings of a study that has systematically reviewed articles from the "Australian Journal of Career Development" from 2004 to 2009. The aim of the study was to…

  3. Rapid E-learning Development Strategies and a Multimedia Project Design Model

    Science.gov (United States)

    Sözcü, Ömer Faruk; Ipek, Ismail

    2014-01-01

    The purpose of the study is to discuss e-learning design strategies which can be used for multimedia projects as a design model. Recent advances in instructional technologies have been found to be very important in the design of training courses by using rapid instructional design (ID) approaches. The approaches were developed to use in training…

  4. Dual-harmonic auto voltage control for the rapid cycling synchrotron of the Japan Proton Accelerator Research Complex

    Directory of Open Access Journals (Sweden)

    Fumihiko Tamura

    2008-07-01

    Full Text Available The dual-harmonic operation, in which the accelerating cavities are driven by the superposition of the fundamental and the second harmonic rf voltage, is useful for acceleration of the ultrahigh intensity proton beam in the rapid cycling synchrotron (RCS of Japan Proton Accelerator Research Complex (J-PARC. However, the precise and fast voltage control of the harmonics is necessary to realize the dual-harmonic acceleration. We developed the dual-harmonic auto voltage control system for the J-PARC RCS. We describe details of the design and the implementation. Various tests of the system are performed with the RCS rf system. Also, a preliminary beam test has been done. We report the test results.

  5. Research in Medicine: Essentials for Developing Countries

    Directory of Open Access Journals (Sweden)

    Yusuf YAKUPOGULLARI

    2014-06-01

    Full Text Available (ExtractThe well-being has been the highest topic for humanity throughout the adventure of mankind on the earth. Therefore, extensive efforts have been performed on the science of medicine, and glorious advances have been gained especially in the last two centuries. Research is essential for medicine to develop new therapeutic methods and to monitor the results of the current treatment given to the patient. These are possibly the simplest reasons for investigations in medicine. On the other hand, qualified human resource, research ethics, financial supports, regular data recording and analysis, and publication are important issues for improvement of the medical researches in the developing countries.... 

  6. GeoNet's `Felt Rapid': Collecting What Is Needed, When You Need It, No More, No Less. Rapid, Volumous Data For Response Versus Detailed, Precise Data For Research

    Science.gov (United States)

    Little, C. L.; McBride, S.; Balfour, N.

    2016-12-01

    New Zealand's geohazard monitoring agency, GeoNet, recently implemented `Felt Rapid': earthquake felt reporting that is quick and simple. GeoNet locates 20,000 earthquakes each year with hundreds of those reported as being felt. Starting in the late 1800s, the New Zealand public has become adept at completing felt reports but feedback since the Canterbury Earthquake Sequence suggested that traditional felt reporting was not meeting researchers' or the public's needs. GeoNet required something rapid, adaptable and robust. The solution was Felt Rapid, a mobile app and website where respondents simply pick from 6 cartoon images - representing Modified Mercalli Intensity (MMI) 3-8 - that best aligned to what they felt. For the last decade, felt reporting has been conducted via the GeoNet website, with additional targeted surveys after damaging earthquakes. The vast majority of the submitted felt reports were for earthquakes too small to cause damage, as these are by far the most frequent. Reports from small events are of little interest to researchers who are only concerned with damaging, MMI6 and above. However, we found that when damaging earthquakes did occur, such as Christchurch's M6.3, they were only sparsely reported (3,776 reports). Understandably, sitting at a computer and completing a lengthy online form wasn't a priority for people after a devastating earthquake. With Felt Rapid, reporting has to be completed within an hour of an earthquake, the use of GeoNet's automatically compiled felt reporting maps had evolved; their main purpose is immediate assessment of an earthquake's impact on populations, and is used by Civil Defence agencies. Reports are immediately displayed on an interactive map via the website and mobile app. With over 250,000 users this provides rapid and robust information regarding the experienced shaking. When a damaging earthquake occurs and researchers want to collect important and rare damaging felt reports, a separate in-depth survey

  7. Laboratory Directed Research ampersand Development Program

    International Nuclear Information System (INIS)

    Ogeka, G.J.; Romano, A.J.

    1993-12-01

    At Brookhaven National Laboratory the Laboratory Directed Research and Development (LDRD) Program is a discretionary research and development tool critical in maintaining the scientific excellence and vitality of the laboratory. It is also a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor in achieving and maintaining staff excellence, and a means to address national needs, within the overall mission of the Department of Energy and Brookhaven National Laboratory. This report summarizes research which was funded by this program during fiscal year 1993. The research fell in a number of broad technical and scientific categories: new directions for energy technologies; global change; radiation therapies and imaging; genetic studies; new directions for the development and utilization of BNL facilities; miscellaneous projects. Two million dollars in funding supported 28 projects which were spread throughout all BNL scientific departments

  8. Participatory Research and Development for Sustainable Agriculture ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Global experiences now show that the changing agenda requires new ways of thinking about and doing research and development. .... the sourcebook, review of paper contributions and participation in critical advisory committee meetings. ...... Creative methodologies are necessary in developing appropriate technologies ...

  9. Gender | Page 227 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Two years ago, the International Development Research Centre created CIME, a development communication program that reflects the interrelations between Communication at the grassroots level, the exchange of Information, two-way Media, and nonformal Education. This book presents the conceptual framework that led ...

  10. Second Language Writing Development: A Research Agenda

    Science.gov (United States)

    Polio, Charlene

    2017-01-01

    In 1998, Wolfe-Quintero, Inagaki & Kim published a monograph describing measures used in assessing writing development. Despite more recent research on linguistic development (e.g., Bulté & Housen 2012; Verspoor, Schmid & Xu 2012; Connor-Linton & Polio 2014), the volume is still a valuable resource and good starting point for…

  11. Applied research and development private sector accomplishments

    International Nuclear Information System (INIS)

    Beskid, N.J.; Devgun, J.S.; Erickson, M.D.; Zielke, M.M.

    1992-01-01

    This report describes the fiscal year 1990 procurement of contracts with the private sector and the current status of applied research and development conducted for DOE's Office of Technology Development (OTD). This report documents the procurement actions, discusses lessons learned from this activity, and disseminates the results of the procurement to interested parties in DOE and in the private sector

  12. Economics | Page 9 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    With a focus on developing countries, this book presents novel comparative research spanning three continents. The result is a more universal and dynamic view of the shaping and reshaping of interactions between firms and universities within different countries at various stages of development. Read more about ...

  13. Economics | Page 8 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    With a focus on developing countries, this book presents novel comparative research spanning three continents. The result is a more universal and dynamic view of the shaping and reshaping of interactions between firms and universities within different countries at various stages of development. Read more about ...

  14. Funding | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    2018-09-30

    IDRC funds projects that aim to bring employment, food security, health, peace, and prosperity to developing regions of the world. We offer grants, funding, and awards to researchers and institutions to find ... Call for: Applications ... citizen of a developing country with a work permit in Canada valid until September 30, 2018;.

  15. Developments in time-resolved high pressure x-ray diffraction using rapid compression and decompression

    International Nuclear Information System (INIS)

    Smith, Jesse S.; Sinogeikin, Stanislav V.; Lin, Chuanlong; Rod, Eric; Bai, Ligang; Shen, Guoyin

    2015-01-01

    Complementary advances in high pressure research apparatus and techniques make it possible to carry out time-resolved high pressure research using what would customarily be considered static high pressure apparatus. This work specifically explores time-resolved high pressure x-ray diffraction with rapid compression and/or decompression of a sample in a diamond anvil cell. Key aspects of the synchrotron beamline and ancillary equipment are presented, including source considerations, rapid (de)compression apparatus, high frequency imaging detectors, and software suitable for processing large volumes of data. A number of examples are presented, including fast equation of state measurements, compression rate dependent synthesis of metastable states in silicon and germanium, and ultrahigh compression rates using a piezoelectric driven diamond anvil cell

  16. [Landscape classification: research progress and development trend].

    Science.gov (United States)

    Liang, Fa-Chao; Liu, Li-Ming

    2011-06-01

    Landscape classification is the basis of the researches on landscape structure, process, and function, and also, the prerequisite for landscape evaluation, planning, protection, and management, directly affecting the precision and practicability of landscape research. This paper reviewed the research progress on the landscape classification system, theory, and methodology, and summarized the key problems and deficiencies of current researches. Some major landscape classification systems, e. g. , LANMAP and MUFIC, were introduced and discussed. It was suggested that a qualitative and quantitative comprehensive classification based on the ideology of functional structure shape and on the integral consideration of landscape classification utility, landscape function, landscape structure, physiogeographical factors, and human disturbance intensity should be the major research directions in the future. The integration of mapping, 3S technology, quantitative mathematics modeling, computer artificial intelligence, and professional knowledge to enhance the precision of landscape classification would be the key issues and the development trend in the researches of landscape classification.

  17. Entrepreneurship research in Spain: developments and distinctiveness.

    Science.gov (United States)

    Sánchez, José C; Gutiérrez, Andrea

    2011-08-01

    This article presents a review of research on entrepreneurship in Spain, paying particular attention to its beginnings, nature and main focus of interest. We have developed a database based on the review of 471 works produced between 1977 and 2009, including articles published in national and international journals and dissertations (read in Spain) that allowed us to extract the following results. There is a preference for qualitative methods, conceptual contributions and the entrepreneurial process as the privileged research theme. There is also a strong focus of interest on micro and small enterprises. These characteristics of Spanish research in areas of entrepreneurship can make a distinctive contribution to international research. However, the dissemination of knowledge and inadequate strategies for international publication limit the diffusion of Spanish research in entrepreneurship. Lastly, we discuss the implications for future research.

  18. Research Resources Survey: Radiology Junior Faculty Development.

    Science.gov (United States)

    Krupinski, Elizabeth A; Votaw, John R

    2015-07-01

    To assess resources available to junior faculty in US academic radiology departments for research mentorship and funding opportunities and to determine if certain resources are more common in successful programs. An anonymous survey covering scientific environment and research mentorship and was sent to vice-chairs of research of radiology departments. Results were evaluated to identify practices of research programs with respect to mentorship, resources, and opportunities. Academy of Radiology Research's 2012 National Institutes of Health (NIH) grants and awards list was used to determine if environment and practices correlate with funding. There was a 51% response rate. A greater fraction of clinical faculty gets promoted from assistant to associate professor than research faculty. Research faculty overall submits more funding applications. Most programs support start-up costs and K-awards. Over half of the departments have a vice-chair for faculty development, and most have formal mentorship programs. Faculty members are expected to teach, engage in service, publish, and apply for and get research funding within 3 years of hire. Top-tier programs as judged by NIH awards have a combination of MDs who devote >50% effort to research and PhD faculty. Key factors holding back both clinical and research junior faculty development were motivation, resources, and time, although programs reported high availability of resources and support at the department level. Better marketing of resources for junior faculty, effort devoted to mentoring clinical faculty in research, and explicit milestones/expectations for achievement could enhance junior faculty success, promote interest in the clinician–scientist career path for radiologists, and lead to greater research success.

  19. Development of Experimental Setup of Metal Rapid Prototyping Machine using Selective Laser Sintering Technique

    Science.gov (United States)

    Patil, S. N.; Mulay, A. V.; Ahuja, B. B.

    2018-04-01

    Unlike in the traditional manufacturing processes, additive manufacturing as rapid prototyping, allows designers to produce parts that were previously considered too complex to make economically. The shift is taking place from plastic prototype to fully functional metallic parts by direct deposition of metallic powders as produced parts can be directly used for desired purpose. This work is directed towards the development of experimental setup of metal rapid prototyping machine using selective laser sintering and studies the various parameters, which plays important role in the metal rapid prototyping using SLS technique. The machine structure in mainly divided into three main categories namely, (1) Z-movement of bed and table, (2) X-Y movement arrangement for LASER movements and (3) feeder mechanism. Z-movement of bed is controlled by using lead screw, bevel gear pair and stepper motor, which will maintain the accuracy of layer thickness. X-Y movements are controlled using timing belt and stepper motors for precise movements of LASER source. Feeder mechanism is then developed to control uniformity of layer thickness metal powder. Simultaneously, the study is carried out for selection of material. Various types of metal powders can be used for metal RP as Single metal powder, mixture of two metals powder, and combination of metal and polymer powder. Conclusion leads to use of mixture of two metals powder to minimize the problems such as, balling effect and porosity. Developed System can be validated by conducting various experiments on manufactured part to check mechanical and metallurgical properties. After studying the results of these experiments, various process parameters as LASER properties (as power, speed etc.), and material properties (as grain size and structure etc.) will be optimized. This work is mainly focused on the design and development of cost effective experimental setup of metal rapid prototyping using SLS technique which will gives the feel of

  20. Developing Ethics and Standards in Action Research

    Directory of Open Access Journals (Sweden)

    Ben Boog

    2008-12-01

    Full Text Available In a globalizing world, what role can social science research – particularly action research – play in order to address the risks of exclusion, poverty, social and physical insecurity and environmental deprivation? More specifically, how can this type of research be conducted in a participatory, responsible, transparent and scientific way? In other words: what about the ethics and standards in action research? This was the main focus of the World Congress on Action Research and Action Learning (August 2006 organized by the University of Groningen and the Higher Education Group of the Northern Netherlands. We begin by discussing the core characteristics of action research with reference to theory and practice. Reflection and action are key constituents of the process through the enactment of action research. The middle section draws upon the research findings presented at the congress and published in a book [B. Boog, J. Preece, M. Slagter and J. Zeelen (Eds. (2008 Towards Quality Improvement of Action Research. Developing Ethics and Standards, Rotterdam/Taipei: Sense Publishers]. Citing authors who contributed chapters to the book mentioned above, we analyze four important subthemes: ‘participation, power and rapport’; ‘quality of research and quality management’; ‘learning to solve your own problems in complex responsive social systems, and ‘heuristics (rules of thumb for action research practice’. Finally, we comment on possible quality improvements for action research. Our remarks relate to the problems of implementing the concept of participation, the ambition of action research to contribute to both knowledge production and social change and the need for systematic reconstruction (scientific validation of action research.

  1. Information Technology Research Services: Powerful Tools to Keep Up with a Rapidly Moving Field

    Science.gov (United States)

    Hunter, Paul

    2010-01-01

    Marty firms offer Information Technology Research reports, analyst calls, conferences, seminars, tools, leadership development, etc. These entities include Gartner, Forrester Research, IDC, The Burton Group, Society for Information Management, 1nfoTech Research, The Corporate Executive Board, and so on. This talk will cover how a number of such services are being used at the Goddard Space Flight Center to improve our IT management practices, workforce skills, approach to innovation, and service delivery. These tools and services are used across the workforce, from the executive leadership to the IT worker. The presentation will cover the types of services each vendor provides and their primary engagement model. The use of these services at other NASA Centers and Headquarters will be included. In addition, I will explain how two of these services are available now to the entire NASA IT workforce through enterprise-wide subscriptions.

  2. Evaluation of simple rapid HIV assays and development of national rapid HIV test algorithms in Dar es Salaam, Tanzania.

    Science.gov (United States)

    Lyamuya, Eligius F; Aboud, Said; Urassa, Willy K; Sufi, Jaffer; Mbwana, Judica; Ndugulile, Faustin; Massambu, Charles

    2009-02-18

    Suitable algorithms based on a combination of two or more simple rapid HIV assays have been shown to have a diagnostic accuracy comparable to double enzyme-linked immunosorbent assay (ELISA) or double ELISA with Western Blot strategies. The aims of this study were to evaluate the performance of five simple rapid HIV assays using whole blood samples from HIV-infected patients, pregnant women, voluntary counseling and testing attendees and blood donors, and to formulate an alternative confirmatory strategy based on rapid HIV testing algorithms suitable for use in Tanzania. Five rapid HIV assays: Determine HIV-1/2 (Inverness Medical), SD Bioline HIV 1/2 3.0 (Standard Diagnostics Inc.), First Response HIV Card 1-2.0 (PMC Medical India Pvt Ltd), HIV1/2 Stat-Pak Dipstick (Chembio Diagnostic System, Inc) and Uni-Gold HIV-1/2 (Trinity Biotech) were evaluated between June and September 2006 using 1433 whole blood samples from hospital patients, pregnant women, voluntary counseling and testing attendees and blood donors. All samples that were reactive on all or any of the five rapid assays and 10% of non-reactive samples were tested on a confirmatory Inno-Lia HIV I/II immunoblot assay (Immunogenetics). Three hundred and ninety samples were confirmed HIV-1 antibody positive, while 1043 were HIV negative. The sensitivity at initial testing of Determine, SD Bioline and Uni-Gold was 100% (95% CI; 99.1-100) while First Response and Stat-Pak had sensitivity of 99.5% (95% CI; 98.2-99.9) and 97.7% (95% CI; 95.7-98.9), respectively, which increased to 100% (95% CI; 99.1-100) on repeat testing. The initial specificity of the Uni-Gold assay was 100% (95% CI; 99.6-100) while specificities were 99.6% (95% CI; 99-99.9), 99.4% (95% CI; 98.8-99.7), 99.6% (95% CI; 99-99.9) and 99.8% (95% CI; 99.3-99.9) for Determine, SD Bioline, First Response and Stat-Pak assays, respectively. There was no any sample which was concordantly false positive in Uni-Gold, Determine and SD Bioline assays. An

  3. Development of rapid methods for relaxation time mapping and motion estimation using magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Gilani, Syed Irtiza Ali

    2008-09-15

    Recent technological developments in the field of magnetic resonance imaging have resulted in advanced techniques that can reduce the total time to acquire images. For applications such as relaxation time mapping, which enables improved visualisation of in vivo structures, rapid imaging techniques are highly desirable. TAPIR is a Look- Locker-based sequence for high-resolution, multislice T{sub 1} relaxation time mapping. Despite the high accuracy and precision of TAPIR, an improvement in the k-space sampling trajectory is desired to acquire data in clinically acceptable times. In this thesis, a new trajectory, termed line-sharing, is introduced for TAPIR that can potentially reduce the acquisition time by 40 %. Additionally, the line-sharing method was compared with the GRAPPA parallel imaging method. These methods were employed to reconstruct time-point images from the data acquired on a 4T high-field MR research scanner. Multislice, multipoint in vivo results obtained using these methods are presented. Despite improvement in acquisition speed, through line-sharing, for example, motion remains a problem and artefact-free data cannot always be obtained. Therefore, in this thesis, a rapid technique is introduced to estimate in-plane motion. The presented technique is based on calculating the in-plane motion parameters, i.e., translation and rotation, by registering the low-resolution MR images. The rotation estimation method is based on the pseudo-polar FFT, where the Fourier domain is composed of frequencies that reside in an oversampled set of non-angularly, equispaced points. The essence of the method is that unlike other Fourier-based registration schemes, the employed approach does not require any interpolation to calculate the pseudo-polar FFT grid coordinates. Translation parameters are estimated by the phase correlation method. However, instead of two-dimensional analysis of the phase correlation matrix, a low complexity subspace identification of the phase

  4. Development of rapid methods for relaxation time mapping and motion estimation using magnetic resonance imaging

    International Nuclear Information System (INIS)

    Gilani, Syed Irtiza Ali

    2008-09-01

    Recent technological developments in the field of magnetic resonance imaging have resulted in advanced techniques that can reduce the total time to acquire images. For applications such as relaxation time mapping, which enables improved visualisation of in vivo structures, rapid imaging techniques are highly desirable. TAPIR is a Look- Locker-based sequence for high-resolution, multislice T 1 relaxation time mapping. Despite the high accuracy and precision of TAPIR, an improvement in the k-space sampling trajectory is desired to acquire data in clinically acceptable times. In this thesis, a new trajectory, termed line-sharing, is introduced for TAPIR that can potentially reduce the acquisition time by 40 %. Additionally, the line-sharing method was compared with the GRAPPA parallel imaging method. These methods were employed to reconstruct time-point images from the data acquired on a 4T high-field MR research scanner. Multislice, multipoint in vivo results obtained using these methods are presented. Despite improvement in acquisition speed, through line-sharing, for example, motion remains a problem and artefact-free data cannot always be obtained. Therefore, in this thesis, a rapid technique is introduced to estimate in-plane motion. The presented technique is based on calculating the in-plane motion parameters, i.e., translation and rotation, by registering the low-resolution MR images. The rotation estimation method is based on the pseudo-polar FFT, where the Fourier domain is composed of frequencies that reside in an oversampled set of non-angularly, equispaced points. The essence of the method is that unlike other Fourier-based registration schemes, the employed approach does not require any interpolation to calculate the pseudo-polar FFT grid coordinates. Translation parameters are estimated by the phase correlation method. However, instead of two-dimensional analysis of the phase correlation matrix, a low complexity subspace identification of the phase

  5. Rapidly Re-Configurable Flight Simulator Tools for Crew Vehicle Integration Research and Design

    Science.gov (United States)

    Pritchett, Amy R.

    2002-01-01

    While simulation is a valuable research and design tool, the time and difficulty required to create new simulations (or re-use existing simulations) often limits their application. This report describes the design of the software architecture for the Reconfigurable Flight Simulator (RFS), which provides a robust simulation framework that allows the simulator to fulfill multiple research and development goals. The core of the architecture provides the interface standards for simulation components, registers and initializes components, and handles the communication between simulation components. The simulation components are each a pre-compiled library 'plugin' module. This modularity allows independent development and sharing of individual simulation components. Additional interfaces can be provided through the use of Object Data/Method Extensions (OD/ME). RFS provides a programmable run-time environment for real-time access and manipulation, and has networking capabilities using the High Level Architecture (HLA).

  6. Research and development in power plant engineering

    International Nuclear Information System (INIS)

    Riedle, K.; Taud, R.

    2001-01-01

    Research and development are a bridge for visions that are escorted to a successful market introduction. Also in power plant engineering, research and development are a lever with which the product power plant, its technology and processes can be adapted to the quickly changing future market. In the overview given by this paper, therefore at first the development boosters and targets are outlined from the viewpoint of the market; then the available technology portfolio is addressed in a concise way. Targets for the development can be seen from the support programmes of the governments. Before a preview is given, some development topics from the point of view of the manufacturer are introduced. (orig.) [de

  7. IL-6 trans-Signaling-Dependent Rapid Development of Cytotoxic CD8+ T Cell Function

    Directory of Open Access Journals (Sweden)

    Jan P. Böttcher

    2014-09-01

    Full Text Available Immune control of infections with viruses or intracellular bacteria relies on cytotoxic CD8+ T cells that use granzyme B (GzmB for elimination of infected cells. During inflammation, mature antigen-presenting dendritic cells instruct naive T cells within lymphoid organs to develop into effector T cells. Here, we report a mechanistically distinct and more rapid process of effector T cell development occurring within 18 hr. Such rapid acquisition of effector T cell function occurred through cross-presenting liver sinusoidal endothelial cells (LSECs in the absence of innate immune stimulation and known costimulatory signaling. Rather, interleukin-6 (IL-6 trans-signaling was required and sufficient for rapid induction of GzmB expression in CD8+ T cells. Such LSEC-stimulated GzmB-expressing CD8+ T cells further responded to inflammatory cytokines, eliciting increased and protracted effector functions. Our findings identify a role for IL-6 trans-signaling in rapid generation of effector function in CD8+ T cells that may be beneficial for vaccination strategies.

  8. Federal Research and Development Funding: FY2009

    Science.gov (United States)

    2009-05-22

    are funded through the NIH Management Fund, financed by taps on other NIH appropriations.) President Bush’s FY2009 budget proposal gave most of the... Alchemy of the 21st Century,” remarks, Texas Academy of Medicine, Engineering and Science Fourth Annual Conference, Austin, Texas, January 4, 2007...significant decrease in financing for MEP. Funding for in-house research and development under the Scientific and Technology Research and Services (STRS

  9. Rotorcraft research in India: recent developments

    OpenAIRE

    Ganguli, Ranjan

    2010-01-01

    Purpose - The purpose of this paper is to discuss published research in rotorcraft which has taken place in India during the last ten years The helicopter research is divided into the following parts health monitoring smart rotor design optimization control helicopter rotor dynamics active control of structural response (ACSR) and helicopter design and development Aspects of health monitoring and smart rotor are discussed in detail Further work needed and areas for international collaboration...

  10. Analysis of Rapidly Developing Low Cloud Ceilings in a Stable Environment

    Science.gov (United States)

    Bauman, William H., III; Barrett, Joe H., III; Case, Jonathan L.; Wheeler, Mark M.; Baggett, G. Wayne

    2006-01-01

    Forecasters at the Space Meteorology Group (SMG) issue 30 to 90 minute forecasts for low cloud ceilings at the Space Shuttle Landing Facility (TTS) to support Space Shuttle landings. Mission verification statistics have shown ceilings to be the number one forecast challenge for SMG. More specifically, forecasters at SMG are concerned with any rapidly developing clouds/ceilings below 8000 ft in a stable, capped thermodynamic environment. Therefore, the Applied Meteorology Unit (AMU) was tasked to examine archived events of rapid stable cloud formation resulting in ceilings below 8000 ft, and document the atmospheric regimes favoring this type of cloud development. The AMU examined the cool season months of November to March during the years of 1993-2003 for days that had low-level inversions and rapid, stable low cloud formation that resulted in ceilings violating the Space Shuttle Flight Rules. The AMU wrote and modified existing code to identify inversions from the morning (-10 UTC) Cape Canaveral, FL rawinsonde (XMR) during the cool season and output pertinent sounding information. They parsed all days with cloud ceilings below 8000 ft at TTS, forming a database of possible rapidly-developing low ceiling events. Days with precipitation or noticeable fog burn-off situations were excluded from the database. In the first phase of this work, only the daytime hours were examined for possible ceiling development events since low clouds are easier to diagnose with visible satellite imagery. Phase II of this work includes expanding the database to include nighttime cases which is underway as this abstract is being written. For the nighttime cases, the AMU will analyze both the 00 UTC soundings and the 10 UTC soundings to examine those data for the presence of a low-level inversion. The 00 UTC soundings will probably not have a surface-based inversion, but the presence of inversions or "neutral" layers aloft and below 8,000 ft will most likely help define the stable

  11. Maturity Models Development in IS Research

    DEFF Research Database (Denmark)

    Lasrado, Lester Allan; Vatrapu, Ravi; Andersen, Kim Normann

    2015-01-01

    Maturity models are widespread in IS research and in particular, IT practitioner communities. However, theoretically sound, methodologically rigorous and empirically validated maturity models are quite rare. This literature review paper focuses on the challenges faced during the development...... literature reveals that researchers have primarily focused on developing new maturity models pertaining to domain-specific problems and/or new enterprise technologies. We find rampant re-use of the design structure of widely adopted models such as Nolan’s Stage of Growth Model, Crosby’s Grid, and Capability...... Maturity Model (CMM). Only recently have there been some research efforts to standardize maturity model development. We also identify three dominant views of maturity models and provide guidelines for various approaches of constructing maturity models with a standard vocabulary. We finally propose using...

  12. Collaborative Engineering for Research and Development

    Science.gov (United States)

    Davis, Jose M.; Keys, L. Ken; Chen, Injazz J.

    2004-01-01

    Research and development (R&D) organizations are being required to be relevant, to be more application-oriented, and to be partners in the strategic management of the business while meeting the same challenges as the rest of the organization, namely: (1) reduced time to market; (2) reduced cost; (3) improved quality; (4) increased reliability; and (5) increased focus on customer needs. Recent advances in computer technology and the Internet have created a new paradigm of collaborative engineering or collaborative product development (CPD), from which new types of relationships among researchers and their partners have emerged. Research into the applicability and benefits of CPD in a low/no production, R&D, and/or government environment is limited. In addition, the supply chain management (SCM) aspects of these relationships have not been studied. This paper presents research conducted at the NASA Glenn Research Center (GRC) investigating the applicability of CPD and SCM in an R&D organization. The study concentrates on the management and implementation of space research activities at GRC. Results indicate that although the organization is engaged in collaborative relationships that incorporate aspects of SCM, a number of areas, such as development of trust and information sharing merit special attention.

  13. Research and development for ethylbenzene production

    Energy Technology Data Exchange (ETDEWEB)

    Xue, Mingwei; Sun, Hongmin; Shen, Zhenhao; Zhang, Bin; Yang, Weimin [SINOPEC Shanghai Research Institute of Petrochemical Technology (China); Huan, Mingyao

    2013-11-01

    Ethylbenzene (EB) is important raw material for the production of styrene. Now, EB is mainly produced by the alkylation of benzene with ethylene catalyzed by zeolite in vapour phase or liquid phase. Shanghai Research Institute of Petrochemical Technology (SRIPT) began to research the catalysts for the production of ethylbenezene in 1993. With near 20 years work, three series of catalysts for the alkylation of benzene with pure ethylene, dilute ethylene and ethanol are in commerical in China. This paper mainly introduced the research and development of SRIPT for the EB production. (orig.)

  14. Management of research and development project

    International Nuclear Information System (INIS)

    Go, Seok Hwa; Hong Jeong Yu; Hyun, Byeong Hwan

    2010-12-01

    This book introduces summary on management of research and development project, prepare of research and development with investigation and analysis of paper, patent and trend of technology, structure of project, management model, management of project, management of project range, management of project time, management of project cost, management of project goods, management of project manpower, management of communication, management of project risk, management of project supply, management of outcome of R and D, management of apply and enroll of patent and management of technology transfer.

  15. Research and development in health education

    DEFF Research Database (Denmark)

    Wistoft, Karen

    2009-01-01

    relatable to health educational development. The overall value theme is elucidated by two development projects that transform as well as challenge specific health-educational practices. This forms the basis of the development of a critical, constructive and practice-oriented perspective on competence......Health professionals working in the field of health promotion and education experience certain value conflicts: their professional and personal values, the values of their clients or of the health services clash with pedagogic values such as participation, involvement, learning and competence...... development. My educational research is concerned with the exploration and development of the knowledge about values and health education related to competence development among health professionals. The purpose is to contribute to systematic knowledge development with a view to support and diversify...

  16. Planar array stack design aided by rapid prototyping in development of air-breathing PEMFC

    Science.gov (United States)

    Chen, Chen-Yu; Lai, Wei-Hsiang; Weng, Biing-Jyh; Chuang, Huey-Jan; Hsieh, Ching-Yuan; Kung, Chien-Chih

    The polymer electrolyte membrane fuel cell (PEMFC) is one of the most important research topics in the new and clean energy area. The middle or high power PEMFCs can be applied to the transportation or the distributed power system. But for the small power application, it is needed to match the power requirement of the product generally. On the other hand, the direct methanol fuel cell (DMFC) is one of the most common type that researchers are interested in, but recently the miniature or the micro-PEMFCs attract more attention due to their advantages of high open circuit voltage and high power density. The objective of this study is to develop a new air-breathing planar array fuel cell stacked from 10 cells made by rapid prototyping technology which has potential for fast commercial design, low cost manufacturing, and even without converters/inverters for the system. In this paper, the main material of flow field plates is acrylonitrile-butadiene-styrene (ABS) which allows the fuel cell be mass-manufactured by plastic injection molding technology. The rapid prototyping technology is applied to construct the prototype and verify the practicability of the proposed stack design. A 10-cell air-breathing miniature PEMFC stack with a volume of 6 cm × 6 cm × 0.9 cm is developed and tested. Its segmented membrane electrode assembly (MEA) is designed with the active surface area of 1.3 cm × 1.3 cm in each individual MEA. The platinum loading at anode and cathode are 0.2 mg cm -2 and 0.4 mg cm -2, respectively. Results show that the peak power densities of the parallel connected and serial connected stack are 99 mW cm -2 at 0.425 V and 92 mW cm -2 at 4.25 V, respectively under the conditions of 70 °C relative saturated humidity (i.e., dew point temperature), ambient temperature and free convection air. Besides, the stack performance is increased under forced convection. If the cell surface air is blown by an electric fan, the peak power densities of parallel connected and

  17. KSC Education Technology Research and Development Plan

    Science.gov (United States)

    Odell, Michael R. L.

    2003-01-01

    Educational technology is facilitating new approaches to teaching and learning science, technology, engineering, and mathematics (STEM) education. Cognitive research is beginning to inform educators about how students learn providing a basis for design of more effective learning environments incorporating technology. At the same time, access to computers, the Internet and other technology tools are becoming common features in K-20 classrooms. Encouraged by these developments, STEM educators are transforming traditional STEM education into active learning environments that hold the promise of enhancing learning. This document illustrates the use of technology in STEM education today, identifies possible areas of development, links this development to the NASA Strategic Plan, and makes recommendations for the Kennedy Space Center (KSC) Education Office for consideration in the research, development, and design of new educational technologies and applications.

  18. Research and development for Canadian nuclear power

    International Nuclear Information System (INIS)

    Robertson, J.A.

    1976-01-01

    Rapid expansion of the successful CANDU reactor system offers immediate substitution for scarce oil and gas, combined with long-term security of energy supplies. A continuing large and vigorous R and D program on nuclear power is essential to achieve these objectives. The program, described here, consists of tactical R and D in support of the current CANDU reactor system, strategic R and D to develop and demonstrate advanced CANDU systems, and exploratory R and D to put Canada in a position to exploit any fusion opportunities. Two support activities, management of radioactive wastes and techniques to safeguard nuclear materials against diversion, although integral components of the nuclear power programs, are identified separately because they are currently of special public interest. (author)

  19. THE INFLUENCE OF CORRUPTION ON CORPORATE GOVERNANCE STANDARDS: SHARED CHARACTERISTICS OF RAPIDLY DEVELOPING ECONOMIES

    Directory of Open Access Journals (Sweden)

    Michelle I. Caron

    2012-01-01

    Full Text Available This article evaluates the relationship between the level of corruption in rapidly developing economies and corporate governance processes therein.  Previous literature illustrates a strong relationship between corporate governance and corruption and suggests that in countries with high levels of corruption, firms lack efficient corporate governance practices.  Similarly, countries with deficient corporate governance practices and low levels of compliance to these standards breed corruption leading to a wide range of transparency dilemmas.  This study delves deeper through careful examination regarding the level of compliance with corporate governance standards and the pervasive effects of corruption on the governance processes of firms with specific regard to rapidly developing economies as well as offering comparisons and similarities of shared characteristics among these countries.

  20. Nuclear Education and Training at Tsinghua University to Meet the Need of the Rapidly Developing Industry

    International Nuclear Information System (INIS)

    Sun, Y.; Han, Y.; Liu, F.

    2016-01-01

    Full text: The Chinese nuclear industry has been expanding rapidly since recent years. Education of highly qualified people with various educational background is an important factor for the efficient and healthy operation of the industry. Tsinghua University is offering various degree programmes for a variety of disciplines including nuclear science, nuclear engineering, nuclear safety, nuclear fuel cycle, nuclear waste treatment, energy policy and management. Degree programmes have been designed and implemented for regular school students who do not have working experience and for people who are already in their career development to better meet the requirement of the rapidly developing nuclear industry. Emphasis has also been given to the internationalization of the education programs. In addition, training programmes on a more practical basis are offered to meet specific purposes. These efforts are briefly described in this paper. (author

  1. Physics Research Integrated Development Environment (PRIDE)

    International Nuclear Information System (INIS)

    Burton, J.; Cormell, L.

    1993-12-01

    Past efforts to implement a Software Engineering approach to High Energy Physics computing have been met with significant resistance and have been, in many cases, only marginally successful. At least a portion of the problem has been the Lick of an integrated development environment, tailored to High Energy Physics and incorporating a suite of Computer Aided Software Engineering tools. The Superconducting Super Collider Physics Research Division Computing Department is implementing pilot projects to develop just such an environment

  2. Evaluation of simple rapid HIV assays and development of national rapid HIV test algorithms in Dar es Salaam, Tanzania

    Directory of Open Access Journals (Sweden)

    Mbwana Judica

    2009-02-01

    Full Text Available Abstract Background Suitable algorithms based on a combination of two or more simple rapid HIV assays have been shown to have a diagnostic accuracy comparable to double enzyme-linked immunosorbent assay (ELISA or double ELISA with Western Blot strategies. The aims of this study were to evaluate the performance of five simple rapid HIV assays using whole blood samples from HIV-infected patients, pregnant women, voluntary counseling and testing attendees and blood donors, and to formulate an alternative confirmatory strategy based on rapid HIV testing algorithms suitable for use in Tanzania. Methods Five rapid HIV assays: Determine™ HIV-1/2 (Inverness Medical, SD Bioline HIV 1/2 3.0 (Standard Diagnostics Inc., First Response HIV Card 1–2.0 (PMC Medical India Pvt Ltd, HIV1/2 Stat-Pak Dipstick (Chembio Diagnostic System, Inc and Uni-Gold™ HIV-1/2 (Trinity Biotech were evaluated between June and September 2006 using 1433 whole blood samples from hospital patients, pregnant women, voluntary counseling and testing attendees and blood donors. All samples that were reactive on all or any of the five rapid assays and 10% of non-reactive samples were tested on a confirmatory Inno-Lia HIV I/II immunoblot assay (Immunogenetics. Results Three hundred and ninety samples were confirmed HIV-1 antibody positive, while 1043 were HIV negative. The sensitivity at initial testing of Determine, SD Bioline and Uni-Gold™ was 100% (95% CI; 99.1–100 while First Response and Stat-Pak had sensitivity of 99.5% (95% CI; 98.2–99.9 and 97.7% (95% CI; 95.7–98.9, respectively, which increased to 100% (95% CI; 99.1–100 on repeat testing. The initial specificity of the Uni-Gold™ assay was 100% (95% CI; 99.6–100 while specificities were 99.6% (95% CI; 99–99.9, 99.4% (95% CI; 98.8–99.7, 99.6% (95% CI; 99–99.9 and 99.8% (95% CI; 99.3–99.9 for Determine, SD Bioline, First Response and Stat-Pak assays, respectively. There was no any sample which was

  3. Non-US electrodynamic launchers research and development

    Energy Technology Data Exchange (ETDEWEB)

    Parker, J.V.; Batteh, J.H.; Greig, J.R.; Keefer, D.; McNab, I.R.; Zabar, Z.

    1994-11-01

    Electrodynamic launcher research and development work of scientists outside the United States is analyzed and assessed by six internationally recognized US experts in the field of electromagnetic and electrothermal launchers. The assessment covers five broad technology areas: (1) Experimental railguns; (2) Railgun theory and design; (3) Induction launchers; (4) Electrothermal guns; (5) Energy storage and power supplies. The overall conclusion is that non-US work on electrodynamic launchers is maturing rapidly after a relatively late start in many countries. No foreign program challenges the US efforts in scope, but it is evident that the United States may be surpassed in some technologies within the next few years. Until recently, published Russian work focused on hypervelocity for research purposes. Within the last two years, large facilities have been described where military-oriented development has been underway since the mid-1980s. Financial support for these large facilities appears to have collapsed, leaving no effective effort to develop practical launchers for military or civilian applications. Electrodynamic launcher research in Europe is making rapid progress by focusing on a single application, tactical launchers for the military. Four major laboratories, in Britain, France, Germany, and the Netherlands, are working on this problem. Though narrower in scope than the US effort, the European work enjoys a continuity of support that has accelerated its progress. The next decade will see the deployment of electrodynamic launcher technology, probably in the form of an electrothermal-chemical upgrade for an existing gun system. The time scale for deployment of electromagnetic launchers is entirely dependent on the level of research-and-development effort. If resources remain limited, the advantage will lie with cooperative efforts that have reasonably stable funding such as the present French-German program.

  4. On Rural Financial and Accounting Work under the Background of Rapid Agricultural Economic Development

    OpenAIRE

    Tang, Yaozheng

    2013-01-01

    Under the background of rapid agricultural economic development, rural financial and accounting work is of great significance. From rural accounting management system, rural accountant allocation and rural accounting training, this paper analyzes current situations of rural accounting work in China. In rural financial and accounting work, there are following problems. (1) Accounting behavior is not standard, and basic accounting work is to be further strengthened; (2) Internal control is not ...

  5. Development of a rapid multi-line detector for industrial computed tomography

    International Nuclear Information System (INIS)

    Nachtrab, Frank; Firsching, Markus; Hofmann, Thomas; Uhlmann, Norman; Neubauer, Harald; Nowak, Arne

    2015-01-01

    In this paper we present the development of a rapid multi-row detector is optimized for industrial computed tomography. With a high frame rate, high spatial resolution and the ability to use up to 450 kVp it is particularly suitable for applications such as fast acquisition of large objects, inline CT or time-resolved 4D CT. (Contains PowerPoint slides). [de

  6. Virtual Reality: Directions in Research and Development.

    Science.gov (United States)

    Stuart, Rory

    1992-01-01

    Discussion of virtual reality (VR) focuses on research and development being carried out at NYNEX to solve business problems. Component technologies are described; design decisions are considered, including interactivity, connectivity, and locus of control; potential perils of VR are discussed, including user dissociation; and areas of promise are…

  7. Publications | Page 11 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 101 - 110 of 6341 ... ... widen the impact of our investment and advance development research. ... By 2030, the World Health Organization (WHO) projects that NCDs such as cancer, diabetes, ... Unravelling the interplay between youth socio-economic ... in Kenya and Uganda, where scientists are looking for cheaper, ...

  8. Publications | Page 29 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 281 - 290 of 6388 ... IDRC works with developing-country researchers and institutions to build local capacity ... to a high-level dialogue that engaged high-level officials and ... The Centers for International Projects Trust (CIPT) organized a ...

  9. Publications | Page 61 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 601 - 610 of 6389 ... IDRC works with developing-country researchers and institutions to ... The result is a more universal and dynamic view of the shaping and reshaping of interactions. ... Pathways to resilience : formal service and informal support use ... ability, divorce or death of their parents, cultural dislocation, and ...

  10. EPR: outlines of research and development

    International Nuclear Information System (INIS)

    Anon.

    1996-01-01

    The articles give an overview of the research and development presently under way for the future pressurized water reactors to be constructed in Europe, and particularly the French and German EPR (European Pressurized Reactor). Such an analysis deals essentially with respect to the pressurized water reactors now in operation. (author)

  11. UCLA accelerator research ampersand development. Progress report

    International Nuclear Information System (INIS)

    1997-01-01

    This report discusses work on advanced accelerators and beam dynamics at ANL, BNL, SLAC, UCLA and Pulse Sciences Incorporated. Discussed in this report are the following concepts: Wakefield acceleration studies; plasma lens research; high gradient rf cavities and beam dynamics studies at the Brookhaven accelerator test facility; rf pulse compression development; and buncher systems for high gradient accelerator and relativistic klystron applications

  12. Publications | Page 18 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 171 - 180 of 6341 ... IDRC works with developing-country researchers and institutions to build ... Any -, Central Asia, Europe, Far East Asia, Middle East, North and Central ... A series of four policy briefs show how poor governance practices, ... the Joint Declaration on ASEAN-Canada Enhanced Partnership 2016-2020.

  13. Publications | Page 47 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 461 - 470 of 6380 ... IDRC works with developing-country researchers and institutions to ... higher than that of men in India, though there is little difference in Brazil. ... partners working to build safe and inclusive cities in Africa, Asia, and Latin America. ... insurance framework to include the enabling conditions and risk ...

  14. Gender | Page 214 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Uncontrolled development was threatening to destroy the forest environment and the traditional way of life of the hill people of Ratanakiri. Researchers worked with the villagers to produce unique maps and resource use plans that convinced the government of the people's traditional resource use and management rights, ...

  15. Engineering Research in Irish Economic Development

    Science.gov (United States)

    Kelly, John

    2011-01-01

    This article summarizes the main findings and recommendations of a report published in December 2010 by the Irish Academy of Engineering (IAE). The report, representing the views of a committee of distinguished Irish engineers from a wide range of disciplines, addresses the role of engineering research in Ireland's economic development and the…

  16. Economics | Page 30 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Globalization is lauded by some as a tool for spreading peace and prosperity, and decried ... This book describes and analyzes the 3-year-long “L-20” project, whose ... in the environment for research and development (R&D) around the world. ... the “capability approach” of economist and Nobel Prize laureate Amartya Sen.

  17. Economics | Page 29 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Globalization is lauded by some as a tool for spreading peace and prosperity, and decried ... This book describes and analyzes the 3-year-long “L-20” project, whose ... in the environment for research and development (R&D) around the world. ... the “capability approach” of economist and Nobel Prize laureate Amartya Sen.

  18. Naval Medical Research and Development Strategic Plan

    Science.gov (United States)

    2008-03-01

    the strategic planning program for action. The pros and cons of the current NMR&D organization structure, management support funding, and officer...Distribution List D-4 Naval Medical Research and Development Strategic Plan March 2008 SWE Naval Surface Warfare Enterprise SWOT Strengths

  19. International Development Research Centre - Special Examination ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    OAG-BVG

    2008-03-27

    Mar 27, 2008 ... The government's attention to these matters is needed. .... that they can identify problems and make decisions that promote ... Canadian resources for research for development by creating, .... effect on the Centre's mandate and strategic objectives. ...... between fresh perspectives and corporate memory.

  20. Fuel Fabrication Capability Research and Development Plan

    Energy Technology Data Exchange (ETDEWEB)

    Senor, David J.; Burkes, Douglas

    2013-06-28

    The purpose of this document is to provide a comprehensive review of the mission of the Fuel Fabrication Capability (FFC) within the Global Threat Reduction Initiative (GTRI) Convert Program, along with research and development (R&D) needs that have been identified as necessary to ensuring mission success. The design and fabrication of successful nuclear fuels must be closely linked endeavors.

  1. Copyright | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Where copyright is held by IDRC Unless otherwise stated, the copyright to material on this website is held by the International Development Research Centre (IDRC). IDRC permits reading, downloading, copying, redistributing, printing, linking and searching, for non-commercial or academic purposes, of any of its content, ...

  2. Sudan | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Our research support has informed the peace and security work of the ... absence of a threat common to all bloc member states, and few shared political goals. ... spin-off, an internship program was developed that includes business, law, and ...

  3. Gender | Page 14 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Learning financial skills through involvement in an urban farming cooperative has improved the lives of women in Amman, Jordan. The article Developing Value Chains ... some form of physical disability. Despite these numbers, little research has been conducted to provide a window into the lives of people with disabilities.

  4. Publications | Page 2 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 11 - 20 of 7327 ... IDRC works with developing-country researchers and institutions to build local capacity through ... Fostering high growth enterprises is key to employment creation, productivity, and economic growth. ... Quality Assurance in Distance Education and eLearning: Challenges and Solutions from Asia.

  5. Publications | Page 16 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 151 - 160 of 6378 ... IDRC works with developing-country researchers and institutions to ... This is one of five cross-cutting issues that have emerged from early ... to a variety of solutions to prevent crime, including mental health support, ...

  6. Publications | Page 35 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 341 - 350 of 6381 ... IDRC works with developing-country researchers and institutions to build local capacity through funding, knowledge sharing, and training. ... The ''Quality Penalty'' refers to the provision of a facility, product, or service of low quality, which is still offered at a price similar to that of higher-quality. The.

  7. Journal of Research in National Development

    African Journals Online (AJOL)

    The Journal of Research in National Development aims to encourage interdisciplinary ... Favorite articles are quantitative, empirical and developmentally biased. .... Tax aggressiveness and corporate social responsibility fluidity in Nigerian firms ... By Country · List All Titles · Free To Read Titles This Journal is Open Access.

  8. Tanzania | Page 33 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    An international research team is developing nanotechnology-based applications of hexanal, a natural plant extract that extends the storage life of harvested fruit. Bananas, mangoes and papayas: these tender tropical fruits are in high demand in export markets and an important livelihood source for producers.

  9. Institutional Support : Ethiopian Development Research Institute ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The Ethiopian Development Research Institute (EDRI) was established in 1999 and became operational in 2003 as a semi-autonomous organization accountable to ... International Water Resources Association, in close collaboration with IDRC, is holding a webinar titled “Climate change and adaptive water management: ...

  10. Gender | Page 212 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Research evidence is supporting the notion that involving women, along with ... The Centre has long valued industry, trade, and commerce as engines of economic growth. From its own practical support for private sector development, IDRC has ... du rôle joué par l'agriculture dans cette ville dynamique d'Afrique de l'Est.

  11. RESEARCH AND DEVELOPMENT INTO HERBAL MEDICINES ...

    African Journals Online (AJOL)

    Recent advances in the Research and development of Herbal Medicines are highlighted and a scheme for R & D work is presented. The need for adequate information (chemical, biological, botanical and so on) on local plants is highlighted. There is also the need to standardize the herbal product, prepare it in an ...

  12. Publications | Page 37 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 361 - 370 of 6373 ... This is the first study investigating the costs of smoking in Cambodia. Both primary and secondary data were collected for this research to provide scientific evidence of direct and indirect health-related costs attributable to smoking, in support of development and implementation of tobacco... Working ...

  13. Applied research opportunities in developed campgrounds

    Science.gov (United States)

    Carl P. Wiedemann

    2002-01-01

    Developed area camping is an important recreational activity in terms of both participation and as a source of revenue for public agencies. A major challenge for administrators in the public sector is how to increase revenues on limited budgets without sacrificing customer satisfaction. Applied research could make a valuable contribution to decision making, but not...

  14. Think Tank Initiative | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The UK Department for International Development. What we do · Funding · Resources · About IDRC. Knowledge. Innovation. Solutions. Careers · Contact Us · Site map. Sign up now for IDRC news and views sent directly to your inbox each month. Subscribe · Copyright · Open access policy · Privacy policy · Research ethics ...

  15. Publications | Page 35 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 341 - 350 of 7330 ... IDRC works with developing-country researchers and ... Using product space methodology, this project aims to analyze the existing ... Plant innate immune response: qualitative and quantitative ... This article discusses the contribution of the Community Work Programme (CWP) to social cohesion, ...

  16. Publications | Page 35 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 341 - 350 of 7331 ... IDRC works with developing-country researchers and institutions to ... Plant innate immune response: qualitative and quantitative ... This article discusses the contribution of the Community Work Programme (CWP) to social cohesion, ... Using product space methodology, this project aims to analyze ...

  17. Publications | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 1 - 10 of 7328 ... IDRC works with developing-country researchers and institutions to build local capacity through ... Visit the IDRC Digital Library now. ... For people living with disabilities that affect their mobility, it's almost impossible to get ...

  18. Economics | Page 19 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Today, just as businesses must compete for survival, growth, and market space, librarians and information professionals must assume a more proactive role to cope with increasing competition. Read more ... Relationships between social policy and human development are the subject of much research and theorizing.

  19. China | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    As the country's political influence in the world increases, we've supported the Chinese government's ... WORLD BANK/S.Harris ... build skills and knowledge to communicate research results and contribute to public debate. develop effective water resource management in the Asian Highlands in response to climate change.

  20. User account | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Log in(active tab) · Request new password. Username *. Enter your IDRC - International Development Research Centre username. Password *. Enter the password that accompanies your username. IDRC Login (for IDRC staff / team members only) · What we do · Funding · Resources · About IDRC. Knowledge. Innovation.

  1. Tradeoffs in Design Research: Development Oriented Triangulation

    NARCIS (Netherlands)

    Koen van Turnhout; Sabine Craenmehr; Robert Holwerda; Mark Menijn; Jan-Pieter Zwart; René Bakker

    2013-01-01

    The Development Oriented Triangulation (DOT) framework in this paper can spark and focus the debate about mixed-method approaches in HCI. The framework can be used to classify HCI methods, create mixed-method designs, and to align research activities in multidisciplinary projects. The framework is

  2. Publications | Page 8 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 71 - 80 of 6343 ... IDRC works with developing-country researchers and institutions to build local ... yet they are rarely valued or accounted for in the market economy. ... The Prospera Digital e-banking program aims to put money in the ...

  3. Government Research and Development Policy for Telecommunications.

    Science.gov (United States)

    Cohen, Linda

    This paper investigates how recent changes in the telecommunications industry are likely to affect government research and development policies by analyzing how changes in the market structure--in particular, increased competition in the industry due to domestic deregulation and international competition--change the political economy of government…

  4. Rationale for energy research and development programme

    Energy Technology Data Exchange (ETDEWEB)

    1976-04-01

    This paper describes the rationale for the expenditure of government money on energy research and development. The Committee, organized in 1974, established the following order of project priorities: projects to determine current and future energy demand; projects concerned with the conservation and more efficient use of energy; projects concerned with the assessment of indigenous energy resources; projects concerned with the assessment of the human, financial, and organizational resources for energy production and use; and projects concerned with economic, technological, social, and environmental aspects of energy use and production over the next 15 years and beyond the next 15 years. Significant factors affecting the national energy economy, the strategy for energy research and development, and the results of committee activities are summarized. An energy scenario research is laid out. (MCW)

  5. The development of laser fusion research

    International Nuclear Information System (INIS)

    Mima, Kunioki

    1998-01-01

    Laser fusion research started soon after the invention of laser. In 1972, the research was declassified and nuclear fusion by laser inplosion was proposed by J. Nuckolls. Since then, 26 years has passed and laser implosion experiments demonstrated 1000 times solid density compression. By the demonstration of 1000 times solid density, the mission of the laser fusion research shifted from 'implosion physics' to 'ignition and high gain', namely demonstration of fusion output of 100 times input laser energy. By the recent developments of laser technology, ultra intense laser became available and opened up a new ignition scheme which is called 'Fast Ignition'. The technology for the diode pumped solid state laser (DPSSL) is developed toward a laser driver for reactor. U.S. and France are constructing MJ lasers for demonstrating ignition and burn and Osaka University is investigating the fast ignition and the equivalent plasma of confinement (EPOC) toward high gain. (author)

  6. The development of laser fusion research

    Energy Technology Data Exchange (ETDEWEB)

    Mima, Kunioki [Osaka Univ., Suita (Japan). Inst. of Laser Engineering

    1998-11-01

    Laser fusion research started soon after the invention of laser. In 1972, the research was declassified and nuclear fusion by laser inplosion was proposed by J. Nuckolls. Since then, 26 years has passed and laser implosion experiments demonstrated 1000 times solid density compression. By the demonstration of 1000 times solid density, the mission of the laser fusion research shifted from `implosion physics` to `ignition and high gain`, namely demonstration of fusion output of 100 times input laser energy. By the recent developments of laser technology, ultra intense laser became available and opened up a new ignition scheme which is called `Fast Ignition`. The technology for the diode pumped solid state laser (DPSSL) is developed toward a laser driver for reactor. U.S. and France are constructing MJ lasers for demonstrating ignition and burn and Osaka University is investigating the fast ignition and the equivalent plasma of confinement (EPOC) toward high gain. (author)

  7. Research and Development Management System (RDMS)

    International Nuclear Information System (INIS)

    Mohd Azidi Abdul Rahman; Abdul Muin Abdul Rahman; Sufian Norazam Mohamed Aris; Saaidi Ismail; Mohamad Safuan Sulaiman; Maizura Ibrahim; Hazizi Omar; Roslan Mohd Ali

    2010-01-01

    Research and Development (R and D) is a main activity carried out at the Malaysian Nuclear Agency particularly in the physical science and nuclear field. The R and D activity that is carried out needs to be managed more efficiently and systematically. Until now all research management activities are carried out manually or semi electronically, beginning from filling in application forms to when the project is completed. Therefore a computerized system is needed in order to manage and monitor R and D projects. The R and D system is capable of giving access information concerning R and D projects which are carried out to users inside and outside the agency. The R and D management system (RDMS) can increase the capability of the Malaysian Nuclear Agency in managing, researching and developing, innovating and inventing technology as well as commercializing the R and D produced. (author)

  8. CE: Original research: hospital system barriers to rapid response team activation: a cognitive work analysis.

    Science.gov (United States)

    Braaten, Jane Saucedo

    2015-02-01

    The goal of rapid response team (RRT) activation in acute care facilities is to decrease mortality from preventable complications, but such efforts have been only moderately successful. Although recent research has shown decreased mortality when RRTs are activated more often, many hospitals have low activation rates. This has been linked to various hospital, team, and nursing factors. Yet there is a dearth of research examining how hospital systems shape nurses' behavior with regard to RRT activation. Making systemic constraints visible and modifying them may be the key to improving RRT activation rates and saving more lives. The purpose of this study was to use cognitive work analysis to describe factors within the hospital system that shape medical-surgical nurses' RRT activation behavior. Cognitive work analysis offers a framework for the study of complex sociotechnical systems. This framework was used as the organizing element of the study. Qualitative descriptive design was used to obtain data to fill the framework's five domains: resources, tasks, strategies, social systems, and worker competency. Data were obtained from interviews with 12 medical-surgical nurses and document review. Directed content analysis was used to place the obtained data into the framework's predefined domains. Many system factors affected participants' decisions to activate or not activate an RRT. Systemic constraints, especially in cases of subtle or gradual clinical changes, included a lack of adequate information, the availability of multiple strategies, the need to justify RRT activation, a scarcity of human resources, and informal hierarchical norms in the hospital culture. The most profound constraint was the need to justify the call. Justification was based on the objective or subjective nature of clinical changes, whether the nurse expected to be able to "handle" these changes, the presence or absence of a physician, and whether there was an expectation of support from the RRT

  9. The Johns Hopkins model of psychological first aid (RAPID-PFA): curriculum development and content validation.

    Science.gov (United States)

    Everly, George S; Barnett, Daniel J; Links, Jonathan M

    2012-01-01

    There appears to be virtual universal endorsement of the need for and value of acute "psychological first aid" (PFA) in the wake of trauma and disasters. In this paper, we describe the development of the curriculum for The Johns Hopkins RAPID-PFA model of psychological first aid. We employed an adaptation of the basic framework for the development of a clinical science as recommended by Millon which entailed: historical review, theoretical development, and content validation. The process of content validation of the RAPID-PFA curriculum entailed the assessment of attitudes (confidence in the application of PFA interventions, preparedness in the application of PFA); knowledge related to the application of immediate mental health interventions; and behavior (the ability to recognize clinical markers in the field as assessed via a videotape recognition exercise). Results of the content validation phase suggest the six-hour RAPID-PFA curriculum, initially based upon structural modeling analysis, can improve confidence in the application of PFA interventions, preparedness in the application of PFA, knowledge related to the application of immediate mental health interventions, and the ability to recognize clinical markers in the field as assessed via a videotape recognition exercise.

  10. Global Information Resources on Rice for Research and Development

    Directory of Open Access Journals (Sweden)

    Shri RAM

    2012-12-01

    Full Text Available Various issues concerning the progress of rice research are related to ambiguous germplasm identification, difficulty in tracing pedigree information, and lack of integration between genetic resources, characterization, breeding, evaluation and utilization data. These issues are the constraints in developing knowledge-intensive crop improvement programs. The rapid growth, development and the global spread of modern information and communication technology allow quick adoption in fundamental research. Thus, there is a need to provide an opportunity for the establishment of services which describe the rice information for better accessibility to information resources used by researchers to enhance the competitiveness. This work reviews some of available resources on rice bioinformatics and their roles in elucidating and propagating biological and genomic information in rice research. These reviews will also enable stakeholders to understand and adopt the change in research and development and share knowledge with the global community of agricultural scientists. The establishment like International Rice Information System, Rice Genome Research Project and Integrated Rice Genome Explorer are major initiatives for the improvement of rice. Creation of databases for comparative studies of rice and other cereals are major steps in further improvement of genetic compositions. This paper will also highlight some of the initiatives and organizations working in the field of rice improvement and explore the availability of the various web resources for the purpose of research and development of rice. We are developing a meta web server for integration of online resources such as databases, web servers and journals in the area of bioinformatics. This integrated platform, with acronym iBIRA, is available online at ibiranet.in. The resources reviewed here are the excerpts from the resources integrated in iBIRA.

  11. Competence Development among mentors: An Action Research

    DEFF Research Database (Denmark)

    Kragelund, Linda

    2014-01-01

    Artiklen er blevet dobbelt blind reviewet og jeg er i gang med at rette den til. This article presents results about student nurse mentors' competence development in relation to exploiting learning opportunities in everyday life activities in hospital wards. They are from the Danish action research...... about them. The research used the concept of 'pseudo-everyday life activities' in which hitherto undiscovered learning opportunities in everyday situations can be exploited, alongside Lauvås and Handal's 'Mentoring loop'. The research sought to establish how mentors’ competence could be improved using...... this framework. The analytical approach was qualitative content analysis. Results were not entirely as expected; they showed that when the tools were used as in the research design, mentors felt they benefitted and evidence indicated their competence would improve. Surprisingly, most mentors did not perform...

  12. Concept development for HLW disposal research tunnel

    International Nuclear Information System (INIS)

    Queon, S. K.; Kim, K. S.; Park, J. H.; Jeo, W. J.; Han, P. S.

    2003-01-01

    In order to dispose high-level radioactive waste in a geological formation, it is necessary to assess the safety of a disposal concept by excavating a research tunnel in the same geological formation as the host rock mass. The design concept of a research tunnel depends on the actual disposal concept, repository geometry, experiments to be carried at the tunnel, and geological conditions. In this study, analysis of the characteristics of the disposal research tunnel, which is planned to be constructed at KAERI site, calculation of the influence of basting impact on neighbor facilities, and computer simuation for mechanical stability analysis using a three-dimensional code, FLAC3D, had been carried out to develop the design concept of the research tunnel

  13. Laboratory directed research and development program, FY 1996

    International Nuclear Information System (INIS)

    1997-02-01

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory's forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances the Laboratory's core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. Areas eligible for support include: (1) Work in forefront areas of science and technology that enrich Laboratory research and development capability; (2) Advanced study of new hypotheses, new experiments, and innovative approaches to develop new concepts or knowledge; (3) Experiments directed toward proof of principle for initial hypothesis testing or verification; and (4) Conception and preliminary technical analysis to explore possible instrumentation, experimental facilities, or new devices

  14. Laboratory directed research and development program, FY 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-01

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory`s forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances the Laboratory`s core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. Areas eligible for support include: (1) Work in forefront areas of science and technology that enrich Laboratory research and development capability; (2) Advanced study of new hypotheses, new experiments, and innovative approaches to develop new concepts or knowledge; (3) Experiments directed toward proof of principle for initial hypothesis testing or verification; and (4) Conception and preliminary technical analysis to explore possible instrumentation, experimental facilities, or new devices.

  15. Are Project Developers Knights and Researchers Queens?

    DEFF Research Database (Denmark)

    Vinstrup, Anya Bjørn

    2014-01-01

    How do project developers at universities view their customers – the researchers, and how do they see themselves as a profession? Does this view influence their motivation and what challenges does it impose? Taking elements of theory from Public Service Motivation (PSM) and linking it with a small...... empirically based survey among the project developers at a centrally located office at a university in Denmark – these questions are sought to be answered. The focal point being the motivation of the project developer, with special emphasis on their user perception, and the practical implications it has...... for leadership and organisational structures....

  16. Unified fuel elements development for research reactors

    International Nuclear Information System (INIS)

    Vatulin, A.; Stetsky, Y.; Dobrikova, I.

    1998-01-01

    Square cross-section rod type fuel elements have been developed for russian pool-type research reactors. new fuel elements can replace the large nomenclature of tubular fuel elements with around, square and hexahedral cross-sections and to solve a problem of enrichment reduction. the fuel assembly designs with rod type fuel elements have been developed. The overall dimensions of existing the assemblies are preserved in this one. the experimental-industrial fabricating process of fuel elements, based on a joint extrusion method has been developed. The fabricating process has been tested in laboratory conditions, 150 experimental fuel element samples of the various sizes were produced. (author)

  17. Developing Short Films of Geoscience Research

    Science.gov (United States)

    Shipman, J. S.; Webley, P. W.; Dehn, J.; Harrild, M.; Kienenberger, D.; Salganek, M.

    2015-12-01

    In today's prevalence of social media and networking, video products are becoming increasingly more useful to communicate research quickly and effectively to a diverse audience, including outreach activities as well as within the research community and to funding agencies. Due to the observational nature of geoscience, researchers often take photos and video footage to document fieldwork or to record laboratory experiments. Here we present how researchers can become more effective storytellers by collaborating with filmmakers to produce short documentary films of their research. We will focus on the use of traditional high-definition (HD) camcorders and HD DSLR cameras to record the scientific story while our research topic focuses on the use of remote sensing techniques, specifically thermal infrared imaging that is often used to analyze time varying natural processes such as volcanic hazards. By capturing the story in the thermal infrared wavelength range, in addition to traditional red-green-blue (RGB) color space, the audience is able to experience the world differently. We will develop a short film specifically designed using thermal infrared cameras that illustrates how visual storytellers can use these new tools to capture unique and important aspects of their research, convey their passion for earth systems science, as well as engage and captive the viewer.

  18. 78 FR 28630 - Pfizer Therapeutic Research, Pfizer Worldwide Research & Development Division, Formerly Known as...

    Science.gov (United States)

    2013-05-15

    ... Research, Pfizer Worldwide Research & Development Division, Formerly Known as Warner Lambert Company... Groton, Connecticut location of Pfizer Therapeutic Research, Pfizer Worldwide Research & Development... Worldwide Research & Development Division, formerly known as Warner Lambert Company, Comparative Medicine...

  19. 1999 LDRD Laboratory Directed Research and Development

    Energy Technology Data Exchange (ETDEWEB)

    Rita Spencer; Kyle Wheeler

    2000-06-01

    This is the FY 1999 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5) engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.

  20. Vero cell technology for rapid development of inactivated whole virus vaccines for emerging viral diseases.

    Science.gov (United States)

    Barrett, P Noel; Terpening, Sara J; Snow, Doris; Cobb, Ronald R; Kistner, Otfried

    2017-09-01

    Rapid development and production of vaccines against emerging diseases requires well established, validated, robust technologies to allow industrial scale production and accelerated licensure of products. Areas covered: A versatile Vero cell platform has been developed and utilized to deliver a wide range of candidate and licensed vaccines against emerging viral diseases. This platform builds on the 35 years' experience and safety record with inactivated whole virus vaccines such as polio vaccine. The current platform has been optimized to include a novel double inactivation procedure in order to ensure a highly robust inactivation procedure for novel emerging viruses. The utility of this platform in rapidly developing inactivated whole virus vaccines against pandemic (-like) influenza viruses and other emerging viruses such as West Nile, Chikungunya, Ross River and SARS is reviewed. The potential of the platform for development of vaccines against other emerging viruses such as Zika virus is described. Expert commentary: Use of this platform can substantially accelerate process development and facilitate licensure because of the substantial existing data set available for the cell matrix. However, programs to provide vaccines against emerging diseases must allow alternative clinical development paths to licensure, without the requirement to carry out large scale field efficacy studies.

  1. Institutional research and development, FY 1988

    International Nuclear Information System (INIS)

    1988-01-01

    The Laboratory's Institutional Research and Development (IR and D) Program was established in 1984 to foster exploratory work to advance science and technology, disciplinary research to develop innovative solutions to support our national defense and energy missions. In FY 1988, the IR and D Program was funded by a 2% assessment on the Laboratory's operating budget. Our policy is to use these funds for researching innovative ideas in LLNL's areas of expertise and for developing new areas of expertise that we perceive to be in the national interest. The technical and scientific accomplishments of each project and of each institute funded this year are presented in this report. The projects were selected because they are expected to advance research in important areas that are too basic or too time consuming to be funded by the developmental programs or because they are somewhat risky projects that have the promise of high payoff. We are continually reappraising the IR and D Program. In particular, we seek new candidates for the Director's Initiatives, and we constantly reassess the work in progress. Each year, we make adjustments to further the Laboratory's policy of using the IR and D Program to fund innovative ideas with high potential for enhancing programmatic activities of national importance

  2. Institutional research and development, FY 1988

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    The Laboratory's Institutional Research and Development (IR and D) Program was established in 1984 to foster exploratory work to advance science and technology, disciplinary research to develop innovative solutions to support our national defense and energy missions. In FY 1988, the IR and D Program was funded by a 2% assessment on the Laboratory's operating budget. Our policy is to use these funds for researching innovative ideas in LLNL's areas of expertise and for developing new areas of expertise that we perceive to be in the national interest. The technical and scientific accomplishments of each project and of each institute funded this year are presented in this report. The projects were selected because they are expected to advance research in important areas that are too basic or too time consuming to be funded by the developmental programs or because they are somewhat risky projects that have the promise of high payoff. We are continually reappraising the IR and D Program. In particular, we seek new candidates for the Director's Initiatives, and we constantly reassess the work in progress. Each year, we make adjustments to further the Laboratory's policy of using the IR and D Program to fund innovative ideas with high potential for enhancing programmatic activities of national importance.

  3. Research and development program, fiscal year 1966

    Energy Technology Data Exchange (ETDEWEB)

    1964-04-01

    The biomedical program of the Laboratory of Nuclear Medicine and Radiation Biology for FY 1966 is conducted within the scope of the following categories: Somatic Effects of Radiation; Combating Detrimental Effects of Radiation; Molecular and Cellular Level Studies; Environmental Radiation Studies; Radiological and Health Physics and Instrumentation; Chemical Toxicity; Cancer Research; and Selected Beneficial Applications. The overall objectives of the Laboratory within these areas of the Biology and Medicine program may be summarized as follows: (1) investigation of the effects of ionizing radiation on living organisms and systems of biological significance; (2) investigation of the dynamic aspects of physiological and biochemical processes in man, animals and plants and how these processes are modified by radiation and related pathological states; (3) the assessment and study of the immediate and long term consequences of the operation or detonation of nuclear devices on the fauna, and flora in man's environment and on man; (4) the development of methods of minimizing or preventing the detrimental effects of ionizing radiation; (5) research in, and development of, beneficial uses of ionizing radiation and radioactive substances in medicine and biology; (6) research in the development of new and more efficient radiation detection devices; (7) research, including field studies, as mutually agreed upon by the Commission and the University, in connection with the conduct of weapon tests and biomedical and civil effects experiments at such tests conducted at continental and overseas test sites; and (8) the conduct of training and educational activities in the biological and medical aspects of radiation and related fields.

  4. 78 FR 28292 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2013-05-14

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board; Notice of Meetings; Amendment The... Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development...

  5. Rapid application development by KEKB accelerator operators using EPICS/Python

    International Nuclear Information System (INIS)

    Tanaka, M.; Satoh, Y.; Kitabayashi, T.

    2004-01-01

    In the KEKB accelerator facility, the control system is constructed based on the framework of EPICS. By using EPICS/Python API, which is originated from KEK, we can develop an EPICS channel access application based on simple Python technology with only a few knowledge of EPICS channel access protocols. The operator's new tuning ideas are quickly implemented to the control system. In this paper, we introduce the EPICS/Python API and report the effectiveness of rapid application development by the KEKB operators using the API. (author)

  6. Research and development of thorium fuel cycle

    International Nuclear Information System (INIS)

    Oishi, Jun.

    1994-01-01

    Nuclear properties of thorium are summarized and present status of research and development of the use of thorium as nuclear fuel is reviewed. Thorium may be used for nuclear fuel in forms of metal, oxide, carbide and nitride independently, alloy with uranium or plutonium or mixture of the compound. Their use in reactors is described. The reprocessing of the spent oxide fuel in thorium fuel cycle is called the thorex process and similar to the purex process. A concept of a molten salt fuel reactor and chemical processing of the molten salt fuel are explained. The required future research on thorium fuel cycle is commented briefly. (T.H.)

  7. Pellet injector research and development at ORNL

    International Nuclear Information System (INIS)

    Combs, S.K.; Barber, G.C.; Baylor, L.R.

    1994-01-01

    Oak Ridge National Laboratory has been developing pellet injectors for plasma fueling experiments on magnetic confinement devices for more than 15 years. Recent major applications of the ORNL development program include (1) a tritium-compatible four-shot pneumatic injector for the Tokamak Fusion Test Reactor, (2) a centrifuge pellet injector for the Tore Supra tokamak, and most recently (3) a three-barrel repeating pneumatic injector for the DIII-D tokamak. In addition to applications, ORNL is developing advanced technologies, including high-speed pellet injectors, tritium injectors, and long-pulse pellet feed systems. The high-speed research involves a collaboration between ORNL and ENEA-Frascati in the development of a repeating two-stage light gas gun based on an extrusion-type pellet feed system. Construction of a new tritium-compatible, extruder-based repeating pneumatic injector (8-mm-diam) is complete and will replace the pipe gun in the original tritium proof-of-principle experiment. The development of a steady-state feed system in which three standard extruders operate in tandem is under way. These research and development activities are relevant to the International Thermonuclear Experimental Reactor and are briefly described in this paper

  8. Exploratory research and development FY90

    International Nuclear Information System (INIS)

    Struble, G.L.; Middleton, C.; Baldwin, G.; Cherniak, J.; Clements, W.; Donohue, M.L.; Francke, A.; Kirvel, R.D.; MacGregor, P.; Shaw, G.

    1990-01-01

    In general, the Exploratory Research and Development (ER ampersand D) Program supports research projects considered too basic or long-range to be funded by other Lawrence Livermore National Laboratory (LLNL) programs. This Program is managed for the Laboratory Director by a special assistant who chairs the LLNL's IR ampersand D Review Committee. Membership in the Review Committee comprises senior LLNL scientists, engineers, and managers whose areas of expertise span the range of scientific disciplines pursued at the Laboratory. The research supported by the Program falls into three categories: Exploratory Research in the Disciplines, Director's Initiatives, and Laboratory-Wide Competition. The first two, Exploratory Research and Director's Initiatives, promote pioneering work in the various scientific disciplines and programmatic areas. Laboratory departments and divisions propose and manage projects in the Exploratory Research category. The Laboratory Director, with the advice of the Review Committee, selects several larger projects to fund as Director's Initiative. These projects, which are proposed and managed by the responsible associate director, are intended to enhance the scope of existing programs or establish new technical directions and programs for the Laboratory. All FY90 projects are described in detail in this report. Other publications on ER ampersand D projects are included in the Publications List at the back of this report

  9. Exploratory research and development FY90

    Energy Technology Data Exchange (ETDEWEB)

    Struble, G.L.; Middleton, C.; Baldwin, G.; Cherniak, J.; Clements, W.; Donohue, M.L.; Francke, A.; Kirvel, R.D.; MacGregor, P.; Shaw, G. (eds.)

    1990-01-01

    In general, the Exploratory Research and Development (ER D) Program supports research projects considered too basic or long-range to be funded by other Lawrence Livermore National Laboratory (LLNL) programs. This Program is managed for the Laboratory Director by a special assistant who chairs the LLNL's IR D Review Committee. Membership in the Review Committee comprises senior LLNL scientists, engineers, and managers whose areas of expertise span the range of scientific disciplines pursued at the Laboratory. The research supported by the Program falls into three categories: Exploratory Research in the Disciplines, Director's Initiatives, and Laboratory-Wide Competition. The first two, Exploratory Research and Director's Initiatives, promote pioneering work in the various scientific disciplines and programmatic areas. Laboratory departments and divisions propose and manage projects in the Exploratory Research category. The Laboratory Director, with the advice of the Review Committee, selects several larger projects to fund as Director's Initiative. These projects, which are proposed and managed by the responsible associate director, are intended to enhance the scope of existing programs or establish new technical directions and programs for the Laboratory. All FY90 projects are described in detail in this report. Other publications on ER D projects are included in the Publications List at the back of this report.

  10. Nuclear boom - challenge for research and development

    International Nuclear Information System (INIS)

    Korec, M.; Liska, P.

    2009-01-01

    In this lecture authors present research and development in which VUJE, a. s. has participated. Authors concluded that resume as soon as possible the short-term research and development tasks for the existing SE reactors, both, operational reactors of SE and for shut-downed reactors - JAVYS. (Financing with the contribution from the state but major part from the industry). In cooperation with state institutions, regulatory authorities and investor (would-be operator) and supplier (suppliers) define and prepare tasks focused on issues of new-built Generation III reactors (Financing split between the state and industry in accordance with the characteristics of the tasks). Begin preparing tasks for resolving development problems of Generation IV reactors: - Persuade politicians abut the inevitability of state participation in the process, including financing; - Involve in the process institutions that can significantly contribute to the problems resolving (mainly on technical level, but also on organization and potentially financial level); - Prepare international cooperation agreements in this field (based on the existing agreements, preparation of new agreements); - Define technical areas of cooperation (research infrastructure, experimental and development facilities, simulation tools).

  11. Laboratory Directed Research and Development Program

    Energy Technology Data Exchange (ETDEWEB)

    Ogeka, G.J.

    1991-12-01

    Today, new ideas and opportunities, fostering the advancement of technology, are occurring at an ever-increasing rate. It, therefore, seems appropriate that a vehicle be available which fosters the development of these new ideas and technologies, promotes the early exploration and exploitation of creative and innovative concepts, and which develops new fundable'' R D projects and programs. At Brookhaven National Laboratory (BNL), one such method is through its Laboratory Directed Research and Development (LDRD) Program. This discretionary research and development tool is critical in maintaining the scientific excellence and vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor achieving and maintaining staff excellence, and a means to address national needs, with the overall mission of the Department of Energy (DOE) and the Brookhaven National Laboratory. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, they have resulted in numerous publications in various professional and scientific journals, and presentations at meetings and forums.

  12. Development and validation of an instrument for rapidly assessing symptoms: the general symptom distress scale.

    Science.gov (United States)

    Badger, Terry A; Segrin, Chris; Meek, Paula

    2011-03-01

    Symptom assessment has increasingly focused on the evaluation of total symptom distress or burden rather than assessing only individual symptoms. The challenge for clinicians and researchers alike is to assess symptoms, and to determine the symptom distress associated with the symptoms and the patient's ability for symptom management without a lengthy and burdensome assessment process. The objective of this article was to discuss the psychometric evaluation of a brief general symptom distress scale (GSDS) developed to assess specific symptoms and how they rank in relation to each other, the overall symptom distress associated with the symptom schema, and provide an assessment of how well or poorly that symptom schema is managed. Results from a pilot study about the initial development of the GSDS with 76 hospitalized patients are presented, followed by a more complete psychometric evaluation of the GSDS using three samples of cancer patients (n=190) and their social network members, called partners in these studies (n=94). Descriptive statistics were used to describe the GSDS symptoms, symptom distress, and symptom management. Point biserial correlations indexed the associations between dichotomous symptoms and continuous measures, and conditional probabilities were used to illustrate the substantial comorbidities of this sample. Internal consistency was examined using the KR-20 coefficient, and test-retest reliability was examined. Construct validity and predictive validity also were examined. The GSDS demonstrated satisfactory internal consistency and test-retest reliability, and good construct validity and predictive validity. The total score on the GSDS, symptom distress, and symptom management correlated significantly with related constructs of depression, positive and negative affect, and general health. The GSDS was able to demonstrate its ability to distinguish between those with or without chronic illness, and was able to significantly predict scores on

  13. Development of an immunochromatographic assay for the rapid detection of bromoxynil in water

    International Nuclear Information System (INIS)

    Zhu Jiang; Chen Wenchao; Lu Yitong; Cheng Guohua

    2008-01-01

    A rapid immunochromatographic one-step strip test was developed to specifically determine bromoxynil in surface and drinking water by competitive inhibition with the nano colloidal gold-conjugated monoclonal antibody (mAb). Bromoxynil standard samples of 0.01-10 mg L -1 in water were tested by this method and the visual limit was 0.06 mg L -1 . The assay only required 5 min and one-step by dispensing a drop of sample solution onto a strip. Parallel analysis of water samples with bromoxynil showed comparable results from one-step strip test and ELISA. Therefore, the one-step strip test is very useful as a screening method for qualitative detection of bromoxynil in water. - One-step strip test is a rapid method for qualitative detection of bromoxynil residues in water

  14. DEVELOPMENT OF NOVEL CERAMIC NANOFILM-FIBER INTEGRATED OPTICAL SENSORS FOR RAPID DETECTION OF COAL DERIVED SYNTHESIS GAS

    Energy Technology Data Exchange (ETDEWEB)

    Junhang Dong; Hai Xiao; Xiling Tang; Hongmin Jiang; Kurtis Remmel; Amardeep Kaur

    2012-09-30

    The overall goal of this project is to conduct fundamental studies on advanced ceramic materials and fiber optic devices for developing new types of high temperature (>500{degree}C) fiber optic chemical sensors (FOCS) for monitoring fossil (mainly coal) and biomass derived gases in power plants. The primary technical objective is to investigate and demonstrate the nanocrystalline doped-ceramic thin film enabled FOCS that possess desired stability, sensitivity and selectivity for in-situ, rapid gas detection in the syngas streams from gasification and combustion flue gases. This report summarizes research works of two integrated parts: (1) development of metal oxide solid thin films as sensing materials for detection and measurement of important gas components relevant to the coal- and biomass-derived syngas and combustion gas streams at high temperatures; and (2) development of fiber optic devices that are potentially useful for constructing FOCS in combination with the solid oxide thin films identified in this program.

  15. Rapid and collaborative development of socially relevant computing solutions for developing communities

    CSIR Research Space (South Africa)

    Mtsweni, J

    2014-11-01

    Full Text Available stakeholders, including communities to work on common social challenges over a short period of time are emerging to address the technological gaps in ICT4D projects. This research expands on the extensive work that has been done over the years in ICT4D projects...

  16. A Lateral Flow Rapid Test for Human Toxocariasis Developed Using Three Toxocara canis Recombinant Antigens.

    Science.gov (United States)

    Yunus, Muhammad Hafiznur; Tan Farrizam, Siti Naqiuyah; Abdul Karim, Izzati Zahidah; Noordin, Rahmah

    2018-01-01

    Laboratory diagnosis of toxocariasis is still a challenge especially in developing endemic countries with polyparasitism. In this study, three Toxocara canis recombinant antigens, rTES-26, rTES-30, and rTES-120, were expressed and used to prepare lateral flow immunoglobulin G4 (IgG4) dipsticks. The concordance of the results of the rapid test (comprising three dipsticks) with a commercial IgG-enzyme-linked immunosorbent assay (ELISA) (Cypress Diagnostics, Belgium) was compared against the concordance of two other commercial IgG-ELISA kits (Bordier, Switzerland and NovaTec, Germany) with the Cypress kit. Using Toxocara- positive samples, the concordance of the dipstick dotted with rTES-26, rTES-30, and rTES-120 was 41.4% (12/29), 51.7% (15/29), and 72.4% (21/29), respectively. When positivity with any dipstick was considered as an overall positive rapid test result, the concordance with the Cypress kit was 93% (27/29). Meanwhile, when compared with the results of the Cypress kit, the concordance of IgG-ELISA from NovaTec and Bordier was 100% (29/29) and 89.7% (26/29), respectively. Specific IgG4 has been recognized as a marker of active infection for several helminthic diseases; therefore, the two non-concordant results of the rapid test when compared with the NovaTec IgG-ELISA kit may be from samples of people with non-active infection. All the three dipsticks showed 100% (50/50) concordance with the Cypress kit when tested with serum from individuals who were healthy and with other infections. In conclusion, the lateral flow rapid test is potentially a good, fast, and easy test for toxocariasis. Next, further validation studies and development of a test with the three antigens in one dipstick will be performed.

  17. Home economics in development through action research

    DEFF Research Database (Denmark)

    Benn, Jette

    2010-01-01

    This research study aimed at describing and developing home economics education through an action research approach in 2 schools and classes grade 6. The study went through 3 phases, an explorative phase with preliminary observations, interviews and discussions with teachers and pupils. Next...... in discursive phase changes have been implemented and conducted in accordance with findings. Third phase the explicative phase results were translated into text books for pupil's grade 4 to7 and to a teachers' guide. The subject is analysed theoretical through a model of the subject and research field. Findings...... and suggestions were discussed in relation to theories of learning, education and home economics. The overall perspectives were to involve pupils, to make them responsible by active and critical participation, and lastly to evaluate education in different ways....

  18. Case management: developing practice through action research.

    Science.gov (United States)

    Smith, Annetta; Mackay, Seonaid; McCulloch, Kathleen

    2013-09-01

    This article is a report of an action research study carried out with community nurses to help develop case management within their practice. Using action research principles, nurses reviewed and analysed their current practice and developed recommendations for further embedding case management as a means of supporting patients with complex care needs in their own homes. Findings indicate that a number of factors can influence the community nurse's ability to implement case management. These factors include approaches to case finding, availability of resources and interprofessional working. Important considerations for nurses were the influence of the context of care, the geographical location and the health needs of the local patient population, which meant that case management may need to be adapted to meet local circumstances.

  19. Development of Bioinformatics Infrastructure for Genomics Research.

    Science.gov (United States)

    Mulder, Nicola J; Adebiyi, Ezekiel; Adebiyi, Marion; Adeyemi, Seun; Ahmed, Azza; Ahmed, Rehab; Akanle, Bola; Alibi, Mohamed; Armstrong, Don L; Aron, Shaun; Ashano, Efejiro; Baichoo, Shakuntala; Benkahla, Alia; Brown, David K; Chimusa, Emile R; Fadlelmola, Faisal M; Falola, Dare; Fatumo, Segun; Ghedira, Kais; Ghouila, Amel; Hazelhurst, Scott; Isewon, Itunuoluwa; Jung, Segun; Kassim, Samar Kamal; Kayondo, Jonathan K; Mbiyavanga, Mamana; Meintjes, Ayton; Mohammed, Somia; Mosaku, Abayomi; Moussa, Ahmed; Muhammd, Mustafa; Mungloo-Dilmohamud, Zahra; Nashiru, Oyekanmi; Odia, Trust; Okafor, Adaobi; Oladipo, Olaleye; Osamor, Victor; Oyelade, Jellili; Sadki, Khalid; Salifu, Samson Pandam; Soyemi, Jumoke; Panji, Sumir; Radouani, Fouzia; Souiai, Oussama; Tastan Bishop, Özlem

    2017-06-01

    Although pockets of bioinformatics excellence have developed in Africa, generally, large-scale genomic data analysis has been limited by the availability of expertise and infrastructure. H3ABioNet, a pan-African bioinformatics network, was established to build capacity specifically to enable H3Africa (Human Heredity and Health in Africa) researchers to analyze their data in Africa. Since the inception of the H3Africa initiative, H3ABioNet's role has evolved in response to changing needs from the consortium and the African bioinformatics community. H3ABioNet set out to develop core bioinformatics infrastructure and capacity for genomics research in various aspects of data collection, transfer, storage, and analysis. Various resources have been developed to address genomic data management and analysis needs of H3Africa researchers and other scientific communities on the continent. NetMap was developed and used to build an accurate picture of network performance within Africa and between Africa and the rest of the world, and Globus Online has been rolled out to facilitate data transfer. A participant recruitment database was developed to monitor participant enrollment, and data is being harmonized through the use of ontologies and controlled vocabularies. The standardized metadata will be integrated to provide a search facility for H3Africa data and biospecimens. Because H3Africa projects are generating large-scale genomic data, facilities for analysis and interpretation are critical. H3ABioNet is implementing several data analysis platforms that provide a large range of bioinformatics tools or workflows, such as Galaxy, the Job Management System, and eBiokits. A set of reproducible, portable, and cloud-scalable pipelines to support the multiple H3Africa data types are also being developed and dockerized to enable execution on multiple computing infrastructures. In addition, new tools have been developed for analysis of the uniquely divergent African data and for

  20. Thorium research and development in Turkey

    International Nuclear Information System (INIS)

    Güngör, Görkem

    2015-01-01

    Turkey has a great potential regarding thorium resources. Thorium exploration activities have been done in the past mainly by state organizations for determining the thorium resources in Turkey. Thorium occurs as complex mineral together with barite, fluorite and rare earth elements (REE). The increase in global demand for REE creates the opportunity for REE production which will also produce thorium as a by-product. The development of nuclear energy program in Turkey provides the stimulus for research and development activities in nuclear technologies. The final declaration of the workshop emphasizes the importance of thorium reserves in Turkey and the necessity for thorium exploration and development activities in order to determine the feasibility of thorium mining and fuel cycle in Turkey. These activities should be conducted together with the development of technologies for separation of these complex minerals and purification of thorium, REE and other minerals to be utilized as commercial products. There are advanced academic research studies on thorium fuel cycle which should be supported by the industry in order to commercialize the results of these studies. Turkey should be integrated to international R and D activities on ADS which is expected to commercialize on medium term. The legislative framework should be developed in order to provide the industrial baseline for nuclear technologies independent from nuclear regulatory activities

  1. Laboratory Directed Research and Development FY 2000

    International Nuclear Information System (INIS)

    Hansen, Todd; Levy, Karin

    2001-01-01

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Annual report on Laboratory Directed Research and Development for FY2000

  2. Research Thinking Development by Teaching Archaeoastronomy

    Science.gov (United States)

    Muglova, P. V.; Stoev, A. D.

    2006-08-01

    A model of research thinking development by teaching archaeoastronomy in specialized three-year extra-curriculum Astronomy programme and creation of favourable socio-educational surroundings is suggested. It is shown as a didactic system of conditions, influences and possibilities of answering specific hierarchic complex of personal needs in the 14 - 18 year age interval. Transformation of these needs in worldly values secures an active position of the students in the educational process and determines their personality development. It is also shown that the Archaeoastronomy School, as an educational environment, executes specific work of students' teaching, upbringing and progress as well as their inclusion in the real process of scientific research. Thus, they have the possibility of generating scientific ideas and obtaining results in the science archaeoastronomy. In consequence of this, their activity acquires social significance. Usages of this model of scientific school in the extra-curriculum Astronomy education reproduces norms and traditions of the real scientific research and directly relay subject content, cultural norms and values of archaeoastronomy in the educative process. Students' participation in archaeoastronomical expeditions, their competent work during the research of concrete archaeoastronomical objects create an investigation style of thinking and steady habits of scientific activity.

  3. Laboratory Directed Research and Development FY 2000

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd; Levy, Karin

    2001-02-27

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Annual report on Laboratory Directed Research and Development for FY2000.

  4. Laboratory directed research and development FY91

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, S.E.; Hedman, I.; Kirvel, R.D.; McGregor, C.K. (eds.)

    1991-01-01

    This review of research programs at Lawrence Livermore National Laboratory is composed of individual papers on various subjects. Broad topics of interest are: chemistry and materials science, computation, earth sciences, engineering, nuclear physics, and physics, and biology. Director's initiatives include the development of a transgenic mouse, accelerator mass spectrometry, high-energy physics detectors, massive parallel computing, astronomical telescopes, the Kuwaiti oil fires and a compact torus accelerator. (GHH)

  5. Laboratory directed research and development FY91

    International Nuclear Information System (INIS)

    Anderson, S.E.; Hedman, I.; Kirvel, R.D.; McGregor, C.K.

    1991-01-01

    This review of research programs at Lawrence Livermore National Laboratory is composed of individual papers on various subjects. Broad topics of interest are: chemistry and materials science, computation, earth sciences, engineering, nuclear physics, and physics, and biology. Director's initiatives include the development of a transgenic mouse, accelerator mass spectrometry, high-energy physics detectors, massive parallel computing, astronomical telescopes, the Kuwaiti oil fires and a compact torus accelerator

  6. Industry Participation in Defence Research and Development,

    Science.gov (United States)

    1983-12-01

    Research and Development: Proposals for Additional Incentives. ASTEC , 1990. K . Interaction between Industry, Higher Education and Government Laboratories...Incentives for Innovation in Australian Industry. ASTEC , 1983. P. Bibliography. Distribution Document Control Data Sheet AWA I A& I 14l2 p/O)OIP (02... ASTEC and the Senate Committee on Science and the Environment. My Department is already preparing advice for me in this regard and I shall ask them to

  7. Research and development in alternative energy sources

    International Nuclear Information System (INIS)

    Lamptey, J.; Moo-Young, M.; Sullivan, H.F.

    1990-01-01

    This paper comprehensively discusses the various bioconversion and thermochemical processes. It recommends that the most urgent research and development issues should relate to direct microbial conversion systems for starch and cellulosic material and to basic biomass combustion rates and mechanisms. An overview of some of the major renewable energy resources and conversion technologies along with the potentials and problems associated with these are also presented.(author). 235 refs., 2 tabs

  8. Laboratory-directed research and development

    International Nuclear Information System (INIS)

    Gerstl, S.A.W.; Caughran, A.B.

    1992-05-01

    This report summarizes progress from the Laboratory-Directed Research and Development (LDRD) program during fiscal year 1991. In addition to a programmatic and financial overview, the report includes progress reports from 230 individual R ampersand D projects in 9 scientific categories: atomic and molecular physics; biosciences; chemistry; engineering and base technologies; geosciences; space sciences, and astrophysics; materials sciences; mathematics and computational sciences; nuclear and particle physics; and plasmas, fluids, and particle beams

  9. The development of an autonomous rendezvous and docking simulation using rapid integration and prototyping technology

    Science.gov (United States)

    Shackelford, John H.; Saugen, John D.; Wurst, Michael J.; Adler, James

    1991-01-01

    A generic planar 3 degree of freedom simulation was developed that supports hardware in the loop simulations, guidance and control analysis, and can directly generate flight software. This simulation was developed in a small amount of time utilizing rapid prototyping techniques. The approach taken to develop this simulation tool, the benefits seen using this approach to development, and on-going efforts to improve and extend this capability are described. The simulation is composed of 3 major elements: (1) Docker dynamics model, (2) Dockee dynamics model, and (3) Docker Control System. The docker and dockee models are based on simple planar orbital dynamics equations using a spherical earth gravity model. The docker control system is based on a phase plane approach to error correction.

  10. Development of a Rapid Real-Time PCR Assay for Quantitation of Pneumocystis carinii f. sp. Carinii

    DEFF Research Database (Denmark)

    Larsen, Hans Henrik; Kovacs, Joseph A; Stock, Frida

    2002-01-01

    A method for reliable quantification of Pneumocystis carinii in research models of P. carinii pneumonia (PCP) that is more convenient and reproducible than microscopic enumeration of organisms would greatly facilitate investigations of this organism. We developed a rapid quantitative touchdown (QTD......) PCR assay for detecting P. carinii f. sp. carinii, the subspecies of P. carinii commonly used in research models of PCP. The assay was based on the single-copy dihydrofolate reductase gene and was able to detect ... 6 log values for standards containing > or =5 copies/tube. Application of the assay to a series of 10-fold dilutions of P. carinii organisms isolated from rat lung demonstrated that it was reproducibly quantitative over 5 log values (r = 0.99). The assay was applied to a recently reported in vitro...

  11. ProteoWizard: open source software for rapid proteomics tools development.

    Science.gov (United States)

    Kessner, Darren; Chambers, Matt; Burke, Robert; Agus, David; Mallick, Parag

    2008-11-01

    The ProteoWizard software project provides a modular and extensible set of open-source, cross-platform tools and libraries. The tools perform proteomics data analyses; the libraries enable rapid tool creation by providing a robust, pluggable development framework that simplifies and unifies data file access, and performs standard proteomics and LCMS dataset computations. The library contains readers and writers of the mzML data format, which has been written using modern C++ techniques and design principles and supports a variety of platforms with native compilers. The software has been specifically released under the Apache v2 license to ensure it can be used in both academic and commercial projects. In addition to the library, we also introduce a rapidly growing set of companion tools whose implementation helps to illustrate the simplicity of developing applications on top of the ProteoWizard library. Cross-platform software that compiles using native compilers (i.e. GCC on Linux, MSVC on Windows and XCode on OSX) is available for download free of charge, at http://proteowizard.sourceforge.net. This website also provides code examples, and documentation. It is our hope the ProteoWizard project will become a standard platform for proteomics development; consequently, code use, contribution and further development are strongly encouraged.

  12. Pellet injector research and development at ORNL

    International Nuclear Information System (INIS)

    Combs, S.K.; Argo, B.E.; Baylor, L.R.; Cole, M.J.; Dyer, G.R.; Fehling, D.T.; Fisher, P.W.; Foster, C.A.; Foust, C.R.; Gouge, M.J.; Jernigan, T.C.; Langley, R.A.; Milora, S.L.; Qualls, A.L.; Schechter, E.; Sparks, D.O.; Tsai, C.C.; Wilgen, J.B.; Whealton, J.W.

    1993-01-01

    A variety of pellet injector designs have been developed at ORNL including single-shot guns that inject one pellet, multiple-shot guns that inject four and eight pellets, machine gun-types (single- and multiple-barrel) that can inject up to >100 pellets, and centrifugal accelerators (mechanical devices that are inherently capable of high repetition rates and long-pulse operation). With these devices, macroscopic pellets (1--6 mm in diameter) composed of hydrogen isotopes are typically accelerated to speeds of ∼1.0 to 2.0 km/s for injection into plasmas of experimental fusion devices. In the past few years, steady progress has been made at ORNL in the development and application of pellet injectors for fueling present-day and future fusion devices. In this paper, we briefly describe some research and development activities at ORNL, including: (1) two recent applications and a new one on large experimental fusion devices, (2) high-velocity pellet injector development, and (3) tritium injector research

  13. Photovoltaic research and development in Japan

    Science.gov (United States)

    Shimada, K.

    1983-01-01

    The status of the Japanese photovoltaic (PV) R&D activities was surveyed through literature searches, private communications, and site visits in 1982. The results show that the Japanese photovoltaic technology is maturing rapidly, consistent with the steady government funding under the Sunshine Project. Two main thrusts of the Project are: (1) completion of the solar panel production pilot plants using cast ingot and sheet silicon materials, and (2) development of large area amorphous silicon solar cells with acceptable efficiency (10 to 12%). An experimental automated solar panel production plant rated at 500 kW/yr is currently under construction for the Sunshine Project for completion in March 1983. Efficiencies demonstrated by experimental large are amorphous silicon solar cells are approaching 8%. Small area amorphous silicon solar cells are, however, currently being mass produced and marketed by several companies at an equivalent annual rate of 2 MW/yr for consumer electronic applications. There is no evidence of an immediate move by the Japanese PV industry to enter extensively into the photovoltaic power market, domestic or otherwise. However, the photovoltaic technology itself could become ready for such an entry in the very near future, especially by making use of advanced process automation technologies.

  14. Research and development quality assurance planning

    Energy Technology Data Exchange (ETDEWEB)

    Hoke, P.B.

    1990-05-14

    Planning for quality assurance (QA) in research and development (R D) is like stealing eggs without waking up the chickens. The QA program should be as unobtrusive as possible. Researchers require a QA program that affords them an environment capable of supporting repeatable experiments with accurate data without unduly stifling their creative abilities. Careful advance planning ensures that the intensity of control provided by quality-related systems is commensurate with the importance and scope of the activities being performed. Good scientific practices applied to small bench-scale projects may require minimal additional controls. As projects increase in size and complexity the controls imposed through planning must, by necessity, be increased. Research and development QA planning, just like any other planning, involves all affected individuals. The application of control systems is determined by factors such as customer or sponsor requirements, the importance of an item or activity to the experiment's success, and the organizational complexity of the project. Many larger experiments are highly dependent on quality-related support activities such as calibration, engineering design, and inspection provided by organizations outside the R D group. Since, in most cases, the expense of support activities is taken directly from funds available for research, it is important for the researchers to be involved in the planning efforts to help determine and agree with the level of QA effort required. A single plan will often suffice for organizations engaged in large numbers of similar experiments. Complex experiments may require unique QA plans or additions to existing plans. Once implemented, the R D QA plans, like any others, require audits or surveillances and may require revisions if the scope of the experiment changes. 1 ref., 1 fig.

  15. Research and development quality assurance planning

    International Nuclear Information System (INIS)

    Hoke, P.B.

    1990-01-01

    Planning for quality assurance (QA) in research and development (R ampersand D) is like stealing eggs without waking up the chickens. The QA program should be as unobtrusive as possible. Researchers require a QA program that affords them an environment capable of supporting repeatable experiments with accurate data without unduly stifling their creative abilities. Careful advance planning ensures that the intensity of control provided by quality-related systems is commensurate with the importance and scope of the activities being performed. Good scientific practices applied to small bench-scale projects may require minimal additional controls. As projects increase in size and complexity the controls imposed through planning must, by necessity, be increased. Research and development QA planning, just like any other planning, involves all affected individuals. The application of control systems is determined by factors such as customer or sponsor requirements, the importance of an item or activity to the experiment's success, and the organizational complexity of the project. Many larger experiments are highly dependent on quality-related support activities such as calibration, engineering design, and inspection provided by organizations outside the R ampersand D group. Since, in most cases, the expense of support activities is taken directly from funds available for research, it is important for the researchers to be involved in the planning efforts to help determine and agree with the level of QA effort required. A single plan will often suffice for organizations engaged in large numbers of similar experiments. Complex experiments may require unique QA plans or additions to existing plans. Once implemented, the R ampersand D QA plans, like any others, require audits or surveillances and may require revisions if the scope of the experiment changes. 1 ref., 1 fig

  16. Research on Adolescent Sexual Orientation: Development, Health Disparities, Stigma, and Resilience

    Science.gov (United States)

    Saewyc, Elizabeth M.

    2011-01-01

    The decade between 1998 and 2008 saw rapid increases in research on adolescent sexual orientation development and related health issues, both in the quantity and in the quality of studies. While much of the research originated in North America, studies from other countries also contributed to emerging understanding of developmental trajectories…

  17. DEVELOPMENT OF RAPID TECHNIQUE FOR DETERMINATION OF THE TOTAL MINERALIZATION OF NATURAL WATERS

    Directory of Open Access Journals (Sweden)

    T. A. Kuchmenko

    2015-01-01

    Full Text Available A new approach has been proposed for rapid and easy evaluation of a indicator of quality and properties of natural water - soluble salt content (mineralization. The method of quartz crystal microbalance is employed at load of the mass-sensitive resonator electrode (BAW-type with investigated water. The degree of correlation between the various indicators related to the contents of salts and insoluble compounds and the level of mineralization obtained by the standard method (gravimetry has been studied. A procedure for salt weighing by single sensor at unilateral load with small sample of natural water has been developed. The optimal conditions for measurement is established using the design of experiment by model 23 . The possibilities of quartz crystal microbalance for determination of non-volatile compounds in the water are described. The calibration of piezosensor is produced by standard solution NaCl (c = 1.000 g / dm3 at optimal conditions of experiment. The adequacy and accuracy of proposed technique is assessed by the correlation between the results of quartz crystal microbalance and conductometry. The correlation between indicators of mineralization established by quartz crystal microbalance and gravimetry is found. It has been obtained an equation that can be used to calculate the standard indicator of the mineralization by the results of a quartz crystal microbalance using single sensor. The approaches to enhance the analytical capabilities of the developed technique for water with low and high mineralization are proposed. The metrological characteristics of quartz crystal microbalance of insoluble compounds in natural water are estimated. A new technique of determination of the mass concentration of the dry residue in water with a conductivity of 0.2 mS or above has been developed, which can be used for rapid analysis of the water at nonlaboratory conditions and in the laboratory for rapid obtaining the information about a sample.

  18. Development of Rapid Isothermal Amplification Assays for Detection of Phytophthora spp. in Plant Tissue.

    Science.gov (United States)

    Miles, Timothy D; Martin, Frank N; Coffey, Michael D

    2015-02-01

    Several isothermal amplification techniques recently have been developed that are tolerant of inhibitors present in many plant extracts, which can reduce the need for obtaining purified DNA for running diagnostic assays. One such commercially available technique that has similarities with real-time polymerase chain reaction (PCR) for designing primers and a labeled probe is recombinase polymerase amplification (RPA). This technology was used to develop two simple and rapid approaches for detection of Phytophthora spp.: one genus-specific assay multiplexed with a plant internal control and the other species-specific assays for Phytophthora ramorum and P. kernoviae. All assays were tested for sensitivity (ranging from 3 ng to 1 fg of DNA) and specificity using DNA extracted from more than 136 Phytophthora taxa, 21 Pythium spp., 1 Phytopythium sp., and a wide range of plant species. The lower limit of linear detection using purified DNA was 200 to 300 fg of DNA in all pathogen RPA assays. Six different extraction buffers were tested for use during plant tissue maceration and the assays were validated in the field by collecting 222 symptomatic plant samples from over 50 different hosts. Only 56 samples were culture positive for Phytophthora spp. whereas 91 were positive using the Phytophthora genus-specific RPA test and a TaqMan real-time PCR assay. A technique for the generation of sequencing templates from positive RPA amplifications to confirm species identification was also developed. These RPA assays have added benefits over traditional technologies because they are rapid (results can be obtained in as little as 15 min), do not require DNA extraction or extensive training to complete, use less expensive portable equipment than PCR-based assays, and are significantly more specific than current immunologically based methods. This should provide a rapid, field-deployable capability for pathogen detection that will facilitate point-of-sample collection processing

  19. Data base system for research and development of high-level waste conditioning

    International Nuclear Information System (INIS)

    Masaki, Toshio; Igarashi, Hiroshi; Ohuchi, Jin; Miyauchi, Tomoko.

    1992-01-01

    Results of research and development for High-Level Waste Conditioning are accumulated as large number of documents. Data Base System for Research and Development of High-Level Waste Conditioning has been developed since 1987 to search for necessary informations correctly and rapidly with the intention of offering and transferring the results to organization inside and outside of PNC. This data base system has contributed that technical informations has been correctly and rapidly searched. Designing of devices etc. and making of reports have become easy and work has been efficiently and rationally accomplished. (author)

  20. Sewage epidemiology and illicit drug research: the development of ethical research guidelines.

    Science.gov (United States)

    Prichard, Jeremy; Hall, Wayne; de Voogt, Pim; Zuccato, Ettore

    2014-02-15

    To discuss the need to develop ethical guidelines for researchers using sewage epidemiology to monitor drug use in the general population and specific precincts, including prisons, schools and workplaces. Describe current applications of sewage epidemiology, identify potential ethical risks associated with this science, and identify key means by which these risks may be mitigated through proportionate ethical guidance that allows this science to be fully developed. A rapidly advancing field of research is sewage epidemiology (SE) - the analysis of wastewater samples to monitor illicit drug use and other substances. Typically this research involves low ethical risks because individual participants cannot be identified and, consequently, review has been waived by human research ethics committees. In the absence of such oversight, ethical research guidelines are recommended for SE teams, peer reviewers and journal editors; guidelines will assist them to mitigate any risks in general population studies and studies of prisons, schools and workplaces. Potential harms include the stigmatisation of participants and, in the prison setting, austere policy responses to SE data that impact negatively upon inmate-participants. The risk of harm can be managed through research planning, awareness of the socio-political context in which results will be interpreted (or, in the case of media, sensationalised) and careful relations with industry partners. Ethical guidelines should be developed in consultation with SE scholars and be periodically amended. They should include publication processes that safeguard scientific rigour and be promulgated through existing research governance structures. Guidelines will assist to promote an ethical research culture among SE teams and scholars involved in the publication process and this will work to protect the reputation of the field. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Development of rapid detection system on BEPC Ⅱ magnet power supply

    International Nuclear Information System (INIS)

    Chen Suying; Zhan Mingchuan; Long Fengli; Ye Weidong

    2014-01-01

    To quickly find the causes of the accelerator unstable or lost beam caused by magnet power supply in Beijing Electron Positron Collider (BEPC Ⅱ) running, the rapid detection system for magnet power supply was developed. The stability of the system in 8 h is about 0.005%, and it can acquire over nearly 500 sets of magnet power supply current values most quickly in 0.33 ms. All data were written to the MySQL database in real time, so as to be able to quickly troubleshoot magnet power supply problem through historical data analysis and comparison. (authors)

  2. RAPID NAMING IN CHILDREN WITH SPECIFIC LANGUAGE IMPAIRMENT AND IN CHILDREN WITH TYPICAL LANGUAGE DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Neda MILOSHEVIĆ

    2017-03-01

    Full Text Available Aimed at the detailed insight into the phonological ability of Serbian-speaking children of preschool age, with and without language impairment, the ability of rapid naming was examined. Method: Operationalization of the set goal was carried out by using the Test for evaluating reading and writing pre-skills. In describing and analyzing the obtained data, methods of descriptive and inferential statistics were used. The sample included 120 subjects of both gender, 40 children diagnosed with specific language impairment (SLI, age from 5,11 to 7 years, and 80 children with typical language development (TLD, age between 5,11 and 7 years, with no statistically significant differences in relation to age and gender of the participants. Results: Summing up the overall results and achievements of children with SLI and children with TLD, we concluded that there are statistically significant differences in the rapid naming between children with specific language impairment and children with typical language development. Conclusions: As it is a global trend to work on preventing disorders and obstructions, and phonological skills in this age are a timely indicator of the development of reading and writing skills, the examined children with SLI are at risk for the occurrence of obstructions and disorders in the area of reading and writing abilities.

  3. Research of private label development in Croatia

    Directory of Open Access Journals (Sweden)

    Sandra Horvat

    2009-07-01

    Full Text Available Private labels have been present on the market since 19th century but their intensive market growth began in the last thirty years after retailers realized what their potential could be in the fight against ever-growing competition. Their market growth has not been distributed equally thought the world so Europe became the region with the highest private label market share, which exceeds 40% on some markets. Although the private label market share in Croatia is considerably smaller, it has also increased steadily over the last decade since private labels were introduced on the market. This paper presents the findings of a research conducted for the purpose of identifying trends in private label development on the Croatian market. The research was conducted through in-depth interviews with private label managers in retail companies in Croatia, and with the managers responsible for private label production in manufacturing companies. The research identified three expected trends of private label development in Croatia and these are: an increase in private label quality, the maintenance of a price gap between private labels and manufacturers’ brands and a further increase in the private label market share.

  4. Action research as a qualitative research approach for understanding technology professional development in higher education

    NARCIS (Netherlands)

    drs Maurice Schols

    2011-01-01

    Over the last two decades, institutions for higher education such as universities and colleges have rapidly expanded and as a result have experienced profound changes in processes of research and organization. However, the rapid expansion and change has fuelled concerns about issues such as

  5. Research and Development Annual Report, 1992

    Science.gov (United States)

    1993-01-01

    Issued as a companion to Johnson Space Center's Research and Technology Annual Report, which reports JSC accomplishments under NASA Research and Technology Operating Plan (RTOP) funding, this report describes 42 additional JSC projects that are funded through sources other than the RTOP. Emerging technologies in four major disciplines are summarized: space systems technology, medical and life sciences, mission operations, and computer systems. Although these projects focus on support of human spacecraft design, development, and safety, most have wide civil and commercial applications in areas such as advanced materials, superconductors, advanced semiconductors, digital imaging, high density data storage, high performance computers, optoelectronics, artificial intelligence, robotics and automation, sensors, biotechnology, medical devices and diagnosis, and human factors engineering.

  6. Safety management in research and development organisation

    International Nuclear Information System (INIS)

    Nivedha, T.

    2016-01-01

    Health and safety is one of the most important aspects of an organizations smooth and effective functioning. It depends on the safety management, health management, motivation, leadership and training, welfare facilities, accident statistics, policy, organization and administration, hazard control and risk analysis, monitoring, statistics and reporting. Workplace accidents are increasingly common, main causes are untidiness, noise, too hot or cold environments, old or poorly maintained machines, and lack of training or carelessness of employees. One of the biggest issues facing employers today is the safety of their employees. This study aims at analyzing the occupational health and safety of Research organization in Indira Gandhi Centre for Atomic Research by gathering information on health management, safety management, motivation, leadership and training, welfare facilities, accident statistics, organization and administration, hazard control and risk analysis, monitoring, statistics and reporting. Data were collected by using questionnaires which were developed on health and safety management system. (author)

  7. DGC - Research and development in the nineties

    International Nuclear Information System (INIS)

    Hinstrup, P.I.

    1992-01-01

    It is claimed that the world's total energy consumption in 1990 increased by 0.4%, whereas natural gas consumption increased by 1.9%. Natural gas comprises 21.6% of the world's consumption of primary energy. In western europe natural gas comprised 16% of the total fuel consumption, in the Northern countries the figure was 5% and in Denmark it constituted 10% of the total fuel consumption during 1990. The author describes the state of natural gas research activities generally throughout the world and emphasizes that the interest in environmental aspects is increasing. Research institutes working with natural gas abroad are briefly mentioned, and the technologies that attract greatest attention in Denmark are described. These include space heating in houses using natural gas - this market is expected to continue to develope. The use of natural gas in industry, and in the transportation sector as an alternative fuel, is also dealt with. (AB)

  8. Rethinking evaluation | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-10-06

    Oct 6, 2010 ... But in a rapidly changing world, how should evaluation methods ... panel discussion at Carleton University hosted by the International ... Public Service Commission, also reflected on the changes triggered by globalization.

  9. Asia | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Asia is undergoing rapid and historic change. ... Our work in Bangladesh supports women's advancement and helps residents respond to ... Our work in Indonesia focuses on technology, the environment, and sustainable forest management.

  10. Research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseases

    Directory of Open Access Journals (Sweden)

    Hai-yang JIANG

    2017-10-01

    Full Text Available Rapid eye movement sleep behavior disorder (RBD is a sleep disorder characterized by the disappearance of muscle relaxation and enacting one's dreams during rapid eye movement (REM, with most of the dreams being violent or aggressive. Prevalence of RBD, based on population, is 0.38%-2.01%, but it becomes much higher in patients with neurodegenerative diseases, especially α - synucleinopathies. RBD may herald the emergence of α-synucleinopathies by decades, thus it may be used as an effective early marker of neurodegenerative diseases. In this review, we summarized the progress on the pathogenesis of RBD and its relationship with neurodegenerative diseases. DOI: 10.3969/j.issn.1672-6731.2017.10.003

  11. Control of research oriented software development

    International Nuclear Information System (INIS)

    Lewis, L.C.; Dronkers, J.J.; Pitsker, B.

    1985-12-01

    The Nuclear Waste Policy Act of 1982 directs the Department of Energy (DOE) to dispose permanently high level radioactive waste and civilian spent nuclear fuel by January 31, 1998. DOE has responded by creating an organizational structure that directs all the activities necessary to carry out the legislative demands. LLNL is conducting research in the earth sciences and is developing some unique computer codes to help establish the feasibility of geologic repositories for nuclear waste. LLNL has several codes under development. This paper examines the administrative and organizational measures that were and still are being undertaken in order to control the development of the two major codes. In the case of one code, the software quality assurance requirements were imposed five years after the code began its development. This required a retroactive application of requirements. The other code is still in the conceptual stages of development and here requirements can be applied as soon as the initial code design begins. Both codes are being developed by scientists, not computer programmers, and both are modeling codes, not data acquisition and reduction codes. Also the projects for which these codes are being developed have slightly different software quality assurance requirements. All these factors contribute unique difficulties in attempts to assure that the development not only results in a reliable prediction, but that whatever the reliability, it can be objectively shown to exist. The paper will examine a software management model. It will also discuss the reasons why it is felt that this particular model would stand a reasonable chance for success. The paper will then describe the way in which the model should be integrated into the existing management configuration and tradition

  12. Laboratory Directed Research and Development FY 1992

    Energy Technology Data Exchange (ETDEWEB)

    Struble, G.L.; Middleton, C.; Anderson, S.E.; Baldwin, G.; Cherniak, J.C.; Corey, C.W.; Kirvel, R.D.; McElroy, L.A. [eds.

    1992-12-31

    The Laboratory Directed Research and Development (LDRD) Program at Lawrence Livermore National Laboratory (LLNL) funds projects that nurture and enrich the core competencies of the Laboratory. The scientific and technical output from the FY 1992 RD Program has been significant. Highlights include (1) Creating the first laser guide star to be coupled with adaptive optics, thus permitting ground-based telescopes to obtain the same resolution as smaller space-based instruments but with more light-gathering power. (2) Significantly improving the limit on the mass of the electron antineutrino so that neutrinos now become a useful tool in diagnosing supernovas and we disproved the existence of a 17-keV neutrino. (3) Developing a new class of organic aerogels that have robust mechanical properties and that have significantly lower thermal conductivity than inorganic aerogels. (4) Developing a new heavy-ion accelerator concept, which may enable us to design heavy-ion experimental systems and use a heavy-ion driver for inertial fusion. (5) Designing and demonstrating a high-power, diode-pumped, solid-state laser concept that will allow us to pursue a variety of research projects, including laser material processing. (6) Demonstrating that high-performance semiconductor arrays can be fabricated more efficiently, which will make this technology available to a broad range of applications such as inertial confinement fusion for civilian power. (7) Developing a new type of fiber channel switch and new fiber channel standards for use in local- and wide-area networks, which will allow scientists and engineers to transfer data at gigabit rates. (8) Developing the nation`s only numerical model for high-technology air filtration systems. Filter designs that use this model will provide safer and cleaner environments in work areas where contamination with particulate hazardous materials is possible.

  13. Laboratory Directed Research and Development FY 1992

    International Nuclear Information System (INIS)

    Struble, G.L.; Middleton, C.; Anderson, S.E.; Baldwin, G.; Cherniak, J.C.; Corey, C.W.; Kirvel, R.D.; McElroy, L.A.

    1992-01-01

    The Laboratory Directed Research and Development (LDRD) Program at Lawrence Livermore National Laboratory (LLNL) funds projects that nurture and enrich the core competencies of the Laboratory. The scientific and technical output from the FY 1992 RD Program has been significant. Highlights include (1) Creating the first laser guide star to be coupled with adaptive optics, thus permitting ground-based telescopes to obtain the same resolution as smaller space-based instruments but with more light-gathering power. (2) Significantly improving the limit on the mass of the electron antineutrino so that neutrinos now become a useful tool in diagnosing supernovas and we disproved the existence of a 17-keV neutrino. (3) Developing a new class of organic aerogels that have robust mechanical properties and that have significantly lower thermal conductivity than inorganic aerogels. (4) Developing a new heavy-ion accelerator concept, which may enable us to design heavy-ion experimental systems and use a heavy-ion driver for inertial fusion. (5) Designing and demonstrating a high-power, diode-pumped, solid-state laser concept that will allow us to pursue a variety of research projects, including laser material processing. (6) Demonstrating that high-performance semiconductor arrays can be fabricated more efficiently, which will make this technology available to a broad range of applications such as inertial confinement fusion for civilian power. (7) Developing a new type of fiber channel switch and new fiber channel standards for use in local- and wide-area networks, which will allow scientists and engineers to transfer data at gigabit rates. (8) Developing the nation's only numerical model for high-technology air filtration systems. Filter designs that use this model will provide safer and cleaner environments in work areas where contamination with particulate hazardous materials is possible

  14. [Attempt for development of rapid word reading test for children--evaluation of reliability and validity].

    Science.gov (United States)

    Hashimoto, Ryusaku; Kashiwagi, Mitsuru; Suzuki, Shuhei

    2008-09-01

    We developed a rapid word reading test for examining the phonological processing ability of Japanese children. We prepared two versions of the test, version A and B. Each test has word and non-word tasks. Twenty-two healthy boys of third grade in primary schools participated in this validation study. For criterion related validity, we performed the serial Hiragana reading test, the sentence reading test, Raven's coloured progressive matrices (RCPM), the Token test for children, the Kana word dictation test, the standardized comprehension test of abstract words (SCTAW), and Trail Circle test. The reading times of the newly developed test correlated moderately or highly with those of the serial Hiragana reading test and the sentence reading test. However, the scores of the other tests (RCPM, Token test for children, Kana word dictation test, SCTAW, Trail Circle test) did not correlated with the reading time of the rapid word reading test. Test-retest reliabilities in the word tasks were more than moderate: 0.52 and 0.76 in versions A and B, while those in the non-word tasks were high: 0.91 and 0.88 in versions A and B. The correlation coefficient between versions A and B was 0.7 for the word tasks and 0.92 for the non-word tasks. This study showed that the rapid word reading test has substantial validity and reliability for testing the phonological processing ability of Japanese children. In addition, the non-word tasks were more suitable for selectively examining the speed of the grapheme to phoneme conversion process.

  15. Development of a prototype for dissolved CO2 rapid measurement and preliminary tests

    Science.gov (United States)

    Li, Meng; Guo, Jinjia; Zhang, Zhihao; Luo, Zhao; Qin, Chuan; Zheng, Ronger

    2017-10-01

    The measurements of dissolved CO2 in seawater is of great significance for the study of global carbon cycle. At present, the commercial sensors used for dissolved CO2 measurements are mostly equipped with permeable membranes for the purpose of gas-liquid separation, with the advantages of easy operation, low cost, etc.. However, most of these devices measure CO2 after reaching gas equilibrium, so it takes a few minutes to respond, which limited its applications in rapid measurements. In this paper, a set of prototype was developed for the rapid measurements of dissolved CO2. The system was built basing the direct absorption TDLAS. To detect the CO2 absorption line located at 4991.26 cm-1 , a fiber-coupled DFB laser operating at 2004 nm was selected as the light source. A Herriott type multi-pass cavity with an effective optical path length of 10 m and an inner volume of 90 mL was used for absorption measurements. A detection limit of 26 μatm can be obtained with this compact cavity. To realize the rapid measurements of dissolved CO2, a degasser with high degassing rate was necessary. A hollow fiber membrane with a large permeable area used in this paper can achieve degassing rate up to 2.88 kPa/min. Benefitted from the high degassing rate of the degasser and high sensitivity of the compact TDLAS system, a rapid measurement of dissolved CO2 in water can be achieved within 1s time, and the response time of the prototype when the dissolved CO2 concentration changed abruptly in actual measurement was 15 s. To evaluate the performance of the prototype, comparison measurements were carried out with a commercial mass spectrometer. The dissolved CO2 in both seawater and tap-water was measured, and the experimental results showed good consistent trends with R2 of 0.973 and 0.931. The experimental results proved the feasibility of dissolved CO2 rapid measurement. In the near future, more system evaluation experiments will be carried out and the system will be further

  16. Decommissioning Technology Development for Nuclear Research Facilities

    International Nuclear Information System (INIS)

    Lee, K. W.; Kang, Y. A.; Kim, G. H.

    2007-06-01

    It is predicted that the decommissioning of a nuclear power plant would happen in Korea since 2020 but the need of partial decommissioning and decontamination for periodic inspection and life extension still has been on an increasing trend and its domestic market has gradually been extended. Therefore, in this project we developed following several essential technologies as a decommissioning R and D. The measurement technology for in-pipe radioactive contamination was developed for measuring alpha/beta/gamma emitting nuclides simultaneously inside a in-pipe and it was tested into the liquid waste transfer pipe in KRR-2. And the digital mock-up system for KRR-1 and 2 was developed for choosing the best scenarios among several scenarios on the basis of various decommissioning information(schedule, waste volume, cost, etc.) that are from the DMU and the methodology of decommissioning cost estimation was also developed for estimating a research reactor's decommissioning cost and the DMU and the decommissioning cost estimation system were incorporated into the decommissioning information integrated management system. Finally the treatment and management technology of the irradiated graphites that happened after decommissioning KRR-2 was developed in order to treat and manage the irradiated graphites safely

  17. Decommissioning Technology Development for Nuclear Research Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Lee, K. W.; Kang, Y. A.; Kim, G. H. (and others)

    2007-06-15

    It is predicted that the decommissioning of a nuclear power plant would happen in Korea since 2020 but the need of partial decommissioning and decontamination for periodic inspection and life extension still has been on an increasing trend and its domestic market has gradually been extended. Therefore, in this project we developed following several essential technologies as a decommissioning R and D. The measurement technology for in-pipe radioactive contamination was developed for measuring alpha/beta/gamma emitting nuclides simultaneously inside a in-pipe and it was tested into the liquid waste transfer pipe in KRR-2. And the digital mock-up system for KRR-1 and 2 was developed for choosing the best scenarios among several scenarios on the basis of various decommissioning information(schedule, waste volume, cost, etc.) that are from the DMU and the methodology of decommissioning cost estimation was also developed for estimating a research reactor's decommissioning cost and the DMU and the decommissioning cost estimation system were incorporated into the decommissioning information integrated management system. Finally the treatment and management technology of the irradiated graphites that happened after decommissioning KRR-2 was developed in order to treat and manage the irradiated graphites safely.

  18. Decommissioning technology development for research reactors

    International Nuclear Information System (INIS)

    Lee, K. W.; Kim, S. K.; Kim, Y. K.

    2004-03-01

    Although it is expected that the decommissioning of a nuclear power plant will happen since 2020, the need of partial decommissioning and decontamination for periodic inspection and life extension has been on an increasing trend and domestic market has gradually been extended. Therefore, in this project the decommissioning DB system on the KRR-1 and 2 was developed as establishing the information classification system of the research reactor dismantling and the structural design and optimization of the decommissioning DB system. Also in order to secure the reliability and safety about the dismantling process, the main dismantling simulation technology that can verify the dismantling process before their real dismantling work was developed. And also the underwater cutting equipment was developed to remove these stainless steel parts highly activated from the RSR. First, the its key technologies were developed and then the design, making, and capability analysis were performed. Finally the actual proof was achieved for applying the dismantling site. an automatic surface contamination measuring equipment was developed in order to get the sample automatically and measure the radiation/radioactivity

  19. Research and Development Joint Development at CEEE - PUCRS

    Energy Technology Data Exchange (ETDEWEB)

    Haffner, Sergio L [Pontificia Univ. Catolica do Rio Grande do Sul, Porto Alegre, RS (Brazil). Escola Politecnica; Fagundes, Jose F. de O. [Companhia Estadual de Energia Eletrica do Estado do Rio Grande do Sul, Porto Alegre, RS (Brazil); Dias, Guilherme A.D.; Cecin, Carlos M

    1994-12-31

    The aim of this work is to present all events realized in Research and Development (R and D) by Companhia Estadual de Energia Eletrica (CEEE) and Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS) in the Electrical Power Systems area. In a brief report it is indicated a chronology of existing cooperation between CEEE and PUCRS, being introduced also the main events of that activity. Finally are showed the main activities performed in the Electrical Power Systems area. (author) 3 refs..

  20. The MSRC research and development program: An update on progress

    International Nuclear Information System (INIS)

    Engelhardt, F.R.

    1993-01-01

    The research and development program of the Marine Spill Response Corporation is solidly under way in a variety of project areas. These include remote sensing, in-situ burning, dispersants, oil water separation, countermeasures effectiveness, bioremediation, and evaluation of spill effects. More than thirty projects have been contracted. Among these are remote sensing studies, which started with in-depth market analyses, technical feasibility evaluations, and field studies. The remote sensing program is engaged in rapid development of a research test bed system, as well as longer-term studies on sensor development and use of satellite systems. In-situ burning studies included a detailed analysis of operational feasibility and information needs; preparations are being made for test burns at sea and improvements of fire-resistant barrier systems. Studies are underway on both aerial dispersant application system development and dispersant effects in selected environments. Studies have commenced on the development of oil water separators for vessels of opportunity used in oil spill response, as well as the related issue of demulsification. The effectiveness of spill countermeasures is being investigated from both engineering and ecological perspectives. Bioremediation projects are under way to promote the development of test systems and on shoreline test sites. Interest continues in test spills in the marine environment, including participation in experimental spills outside the United States and a search for possible scenarios where such field experiments can be carried out in United States waters. In all of these project areas, the research and development program stresses information transfer by way of meetings and publications, and is initiating publication of a peer reviewed international journal on oil spill science and technology

  1. Safeguards technology research and development at CIAE

    International Nuclear Information System (INIS)

    Yang Qun

    2001-01-01

    Full text: China Institute of Atomic Energy (CIAE) is a multi-disciplinary institute under the leadership of China National Nuclear Corporation (CNNC). The Laboratory of Technical Research for Nuclear Safeguards was established at CIAE in 1991 to develop safeguards technology and to provide technical assistance to competent authorities for nuclear material management and control, which became one of the key laboratories approved by CNNC in 1993. The main research works for safeguards at CIAE include: nuclear material control and accounting, facilities license review and assessment, domestic inspection, NDA and DA analysis, physical protection and technical training. Research and development of equipment and technique for safeguards has been continuing at CIAE. A variety of NDA equipment that has different resolution and analysis capability has been developed. Method of NDA measurement has been investigated for nuclear material with different characteristics. Mathematics method such as Monte Carlo simulation is applied in NDA. Advanced destructive analysis (DA) instrument is installed at laboratory of CIAE, such as TIMS, ICP-MS and electronic chemistry analyzing system. The high accuracy results of element analysis and isotopic analysis for nuclear material can be obtained. It is possible to measure the types and quantities of nuclear material in a given area by means of NDA and DA. Physical protection system has also been developed. It consists of access control and management, various alarm (including perimeter alarm, intrusion alarms, fire alarms), video and audio monitors, intercommunication set and central console. The system can meet technical requirement for safeguards of first rank. Nuclear material accounting is an important aspect of safeguards research at CIAE. The computer software related to material accounting has been developed. It is the important task for scientists at CIAE to design and review nuclear accounting systems in various facilities. For

  2. Prehospital care training in a rapidly developing economy: a multi-institutional study.

    Science.gov (United States)

    Vyas, Dinesh; Hollis, Michael; Abraham, Rohit; Rustagi, Neeti; Chandra, Siddharth; Malhotra, Ajai; Rajpurohit, Vikas; Purohit, Harshada; Pal, Ranabir

    2016-06-01

    The trauma pandemic is one of the leading causes of death worldwide but especially in rapidly developing economies. Perhaps, a common cause of trauma-related mortality in these settings comes from the rapid expansion of motor vehicle ownership without the corresponding expansion of national prehospital training in developed countries. The resulting road traffic injuries often never make it to the hospital in time for effective treatment, resulting in preventable disability and death. The current article examines the development of a medical first responder training program that has the potential to reduce this unnecessary morbidity and mortality. An intensive training workshop has been differentiated into two progressive tiers: acute trauma training (ATT) and broad trauma training (BTT) protocols. These four-hour and two-day protocols, respectively, allow for the mass education of laypersons-such as police officials, fire brigade, and taxi and/or ambulance drivers-who are most likely to interact first with prehospital victims. Over 750 ATT participants and 168 BTT participants were trained across three Indian educational institutions at Jodhpur and Jaipur. Trainees were given didactic and hands-on education in a series of critical trauma topics, in addition to pretraining and post-training self-assessments to rate clinical confidence across curricular topics. Two-sample t-test statistical analyses were performed to compare pretraining and post-training confidence levels. Program development resulted in recruitment of a variety of career backgrounds for enrollment in both our ATT and BTT workshops. The workshops were run by local physicians from a wide spectrum of medical specialties and previously ATT-trained police officials. Statistically significant improvements in clinical confidence across all curricular topics for ATT and BTT protocols were identified (P developing settings. Program expansion can offer an exponential growth in the training rate of medical

  3. Nuclear energy research and development in France

    International Nuclear Information System (INIS)

    Patarin, L.

    1981-02-01

    Having described the general organization and main participants in charge of nuclear energy development in France, headed by the C.E.A. since the start of this activity at the end of World War II, the author gives a glimpse of the programmes shared out between four main headings: fundamental research, reactors, fuel cycle and nuclear safety. Two tables sum up the financial means of the C.E.A. in 1981 on the one hand and the personnel strengths on the other. A graph also shows the operational framework of the C.E.A. and its main subsidiaries and participations [fr

  4. Excellent fruits of national research and development

    International Nuclear Information System (INIS)

    2008-12-01

    This book introduces 100 excellent fruits of research and development in Korea. Such as. It show the titles of 100 excellent fruits about technology of hope to give people healthy life, technology of product and abundance to enrich resource, technology to make green growth and sound society, next service technology to communicate with network, new electron technology to brings life change, technology to draw innovation of industrial fields, technology to build higher value-added product with new fusion materials and technology to share and to create future knowledge.

  5. Quality assurance in research and development

    International Nuclear Information System (INIS)

    Laslett, G.F.; Waker, C.H.

    1990-01-01

    It is propounded that, given high status for the Research and Development (R and D) activity of the comapny or site, ''freeing'' the scientists and engineers involved at the innovative decision-taking point helps quality. Effort and money to raise the latter may be best spent in ensuring better calibre, background and training of them, making more meaningful the teamwork across the supplier/customer interfaces, and avoiding risk of misunderstanding of the use to be made of the outcome of the R and D endeavour. But the staff's conscience towards quality, hand in hand with safety, must be constantly stimulated. (author)

  6. Development of a rapid agglutination latex test for diagnosis of enteropathogenic and enterohemorrhagic Escherichia coli infection in developing world: defining the biomarker, antibody and method.

    Directory of Open Access Journals (Sweden)

    Letícia B Rocha

    2014-09-01

    Full Text Available Enteropathogenic and enterohemorrhagic Escherichia coli (EPEC/EHEC are human intestinal pathogens responsible for diarrhea in both developing and industrialized countries. In research laboratories, EPEC and EHEC are defined on the basis of their pathogenic features; nevertheless, their identification in routine laboratories is expensive and laborious. Therefore, the aim of the present work was to develop a rapid and simple assay for EPEC/EHEC detection. Accordingly, the EPEC/EHEC-secreted proteins EspA and EspB were chosen as target antigens.First, we investigated the ideal conditions for EspA/EspB production/secretion by ELISA in a collection of EPEC/EHEC strains after cultivating bacterial isolates in Dulbecco's modified Eagle's medium (DMEM or DMEM containing 1% tryptone or HEp-2 cells-preconditioned DMEM, employing either anti-EspA/anti-EspB polyclonal or monoclonal antibodies developed and characterized herein. Subsequently, a rapid agglutination latex test (RALT was developed and tested with the same collection of bacterial isolates.EspB was defined as a biomarker and its corresponding monoclonal antibody as the tool for EPEC/EHEC diagnosis; the production of EspB was better in DMEM medium. RALT assay has the sensitivity and specificity required for high-impact diagnosis of neglected diseases in the developing world.RALT assay described herein can be considered an alternative assay for diarrhea diagnosis in low-income countries since it achieved 97% sensitivity, 98% specificity and 97% efficiency.

  7. 77 FR 26069 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2012-05-02

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board, Notice of Meeting Amendment The... Development and Clinical Science Research and Development Services Scientific Merit Review Board have changed...

  8. Development of Global Change Research in Developing Countries

    Science.gov (United States)

    Sierra, Carlos A.; Yepes, Adriana P.

    2010-10-01

    Ecosystems and Global Change in the Context of the Neotropics; Medellín, Colombia, 19-20 May 2010; Research in most areas of global environmental change is overwhelmingly produced outside developing countries, which are usually consumers rather than producers of the knowledge associated with their natural resources. While there have been important recent advances in understanding the causes of global-¬scale changes and their consequences to the functioning of tropical ecosystems, there is still an important gap in the understanding of these changes at regional and national levels (where important political decisions are usually made). A symposium was held with the aim of surveying the current state of research activities in a small, developing country such as Colombia. It was jointly organized by the Research Center on Ecosystems and Global Change, Carbono and Bosques; the National University of Colombia at Medellín and the Colombian Ministry of the Environment, Housing, and Regional Development. This 2-¬day symposium gathered Colombian and international scientists involved in different areas of global environmental change, tropical ecosystems, and human societies.

  9. Microstructural development in a rapidly solidified Al-Fe-V-Si alloy

    International Nuclear Information System (INIS)

    Park, W.J.; Baek, E.R.; Lee, Sunghak; Kim, N.J.

    1991-01-01

    TEM is used to investigate microstructural development in a rapidly solidified Al-Fe-V-Si alloy. The as-cast microstructure of a rapidly solidified Al-Fe-V-Si alloy was found to vary depending on casting conditions and also through the thickness of ribbon. For completely Zone A ribbon, intercellular phase consists of a microquasi-crystalline phase, while for the Zone A and Zone B mixed ribbon, it consists of a silicide phase. In either case, formation of globular particles of a cluster microquasi-crystalline phase is observed near the air side of the ribbon. Annealing study shows significant differences in the final microstructure depending on the initial status of the ribbon. Completely Zone A ribbon, whose microstructure is composed of a microquasi-crystalline phase, results in a very coarse microstructure after annealing as compared to the Zone A and Zone B mixed ribbon. This result has important implications for the development of high-performance elevated-temperature Al alloys. 12 refs

  10. Photogrammetry for rapid prototyping: development of noncontact 3D reconstruction technologies

    Science.gov (United States)

    Knyaz, Vladimir A.

    2002-04-01

    An important stage of rapid prototyping technology is generating computer 3D model of an object to be reproduced. Wide variety of techniques for 3D model generation exists beginning with manual 3D models generation and finishing with full-automated reverse engineering system. The progress in CCD sensors and computers provides the background for integration of photogrammetry as an accurate 3D data source with CAD/CAM. The paper presents the results of developing photogrammetric methods for non-contact spatial coordinates measurements and generation of computer 3D model of real objects. The technology is based on object convergent images processing for calculating its 3D coordinates and surface reconstruction. The hardware used for spatial coordinates measurements is based on PC as central processing unit and video camera as image acquisition device. The original software for Windows 9X realizes the complete technology of 3D reconstruction for rapid input of geometry data in CAD/CAM systems. Technical characteristics of developed systems are given along with the results of applying for various tasks of 3D reconstruction. The paper describes the techniques used for non-contact measurements and the methods providing metric characteristics of reconstructed 3D model. Also the results of system application for 3D reconstruction of complex industrial objects are presented.

  11. Development of Loop-Mediated Isothermal Amplification (LAMP) Assay for Rapid Detection of Cannabis sativa.

    Science.gov (United States)

    Kitamura, Masashi; Aragane, Masako; Nakamura, Kou; Watanabe, Kazuhito; Sasaki, Yohei

    2016-07-01

    In many parts of the world, the possession and cultivation of Cannabis sativa L. are restricted by law. As chemical or morphological analyses cannot identify the plant in some cases, a simple yet accurate DNA-based method for identifying C. sativa is desired. We have developed a loop-mediated isothermal amplification (LAMP) assay for the rapid identification of C. sativa. By optimizing the conditions for the LAMP reaction that targets a highly conserved region of tetrahydrocannabinolic acid (THCA) synthase gene, C. sativa was identified within 50 min at 60-66°C. The detection limit was the same as or higher than that of conventional PCR. The LAMP assay detected all 21 specimens of C. sativa, showing high specificity. Using a simple protocol, the identification of C. sativa could be accomplished within 90 min from sample treatment to detection without use of special equipment. A rapid, sensitive, highly specific, and convenient method for detecting and identifying C. sativa has been developed and is applicable to forensic investigations and industrial quality control.

  12. Development of Colloidal Gold-Based Immunochromatographic Assay for Rapid Detection of Goose Parvovirus

    Directory of Open Access Journals (Sweden)

    Xianglong Yu

    2018-05-01

    Full Text Available Goose parvovirus (GPV remains as a worldwide problem in goose industry. For this reason, it is necessary to develop a new diagnostic approach that is easier and faster than conventional tests. A rapid immunochromatographic assay based on antibody colloidal gold nanoparticles specific to GPV was developed for the detection of GPV in goose allantoic fluid and supernatant of tissue homogenate. The monoclonal antibodies (Mab was produced by immunizing the BALB/c mice with purified GPV suspension, and the polyclonal antibody (pAb was produced by immunizing the rabbits with recombinant VP3 protein. The colloidal gold was prepared by the reduction of gold salt with sodium citrate coupled with Mab against GPV. The optimal concentrations of the coating antibody and capture antibody were determined to be 1.6 mg/ml and 9 μg/ml. With visual observation, the lower limit was found to be around 1.2 μg/ml. Common diseases of goose were tested to evaluate the specificity of the immune colloidal gold (ICG strip, and no cross-reaction was observed. The clinical detection was examined by carrying out the ICG strip test with 92 samples and comparing the results of these tests with those obtained via agar diffusion test and polymerase chain reaction (PCR test. Therefore, the ICG strip test was a sufficiently sensitive and accurate detection method for a rapid screening of GPV.

  13. Development of a Loop-Mediated Isothermal Amplification Assay for Rapid Detection of BK Virus▿

    Science.gov (United States)

    Bista, Bipin Raj; Ishwad, Chandra; Wadowsky, Robert M.; Manna, Pradip; Randhawa, Parmjeet Singh; Gupta, Gaurav; Adhikari, Meena; Tyagi, Rakhi; Gasper, Gina; Vats, Abhay

    2007-01-01

    Loop-mediated isothermal amplification (LAMP) is a novel method for rapid amplification of DNA. Its advantages include rapidity and minimal equipment requirement. The LAMP assay was developed for BK virus (BKV), which is a leading cause of morbidity in renal transplant recipients. The characteristics of the assay, including its specificity and sensitivity, were evaluated. BKV LAMP was performed using various incubation times with a variety of specimens, including unprocessed urine and plasma samples. A ladder pattern on gel electrophoresis, typical of successful LAMP reactions, was observed specifically only for BKV and not for other viruses. The sensitivity of the assay with 1 h of incubation was 100 copies/tube of a cloned BKV fragment. Additionally, a positive reaction was visually ascertained by a simple color reaction using SYBR green dye. BKV LAMP was also successful for urine and plasma specimens without the need for DNA extraction. Due to its simplicity and specificity, the LAMP assay can potentially be developed for “point of care” screening of BKV. PMID:17314224

  14. Development of a loop-mediated isothermal amplification assay for rapid detection of BK virus.

    Science.gov (United States)

    Bista, Bipin Raj; Ishwad, Chandra; Wadowsky, Robert M; Manna, Pradip; Randhawa, Parmjeet Singh; Gupta, Gaurav; Adhikari, Meena; Tyagi, Rakhi; Gasper, Gina; Vats, Abhay

    2007-05-01

    Loop-mediated isothermal amplification (LAMP) is a novel method for rapid amplification of DNA. Its advantages include rapidity and minimal equipment requirement. The LAMP assay was developed for BK virus (BKV), which is a leading cause of morbidity in renal transplant recipients. The characteristics of the assay, including its specificity and sensitivity, were evaluated. BKV LAMP was performed using various incubation times with a variety of specimens, including unprocessed urine and plasma samples. A ladder pattern on gel electrophoresis, typical of successful LAMP reactions, was observed specifically only for BKV and not for other viruses. The sensitivity of the assay with 1 h of incubation was 100 copies/tube of a cloned BKV fragment. Additionally, a positive reaction was visually ascertained by a simple color reaction using SYBR green dye. BKV LAMP was also successful for urine and plasma specimens without the need for DNA extraction. Due to its simplicity and specificity, the LAMP assay can potentially be developed for "point of care" screening of BKV.

  15. Trends of Photovoltaic Research, Development and Diffusion

    Energy Technology Data Exchange (ETDEWEB)

    Song, J. S.; Yoon, K. H.; Yu, K. J. [Korea Institute of Energy Research (Korea)

    2000-07-01

    The Korean National Photovoltaic Project was initiated on October 1989 to develop technologies for the generation of economically competitive electric power by photovoltaic systems. It consists of four stages through the year 2006 with technical goals and cost targets related with solar cells, balance of systems and system application. The objectives of the project are to utilize photovoltaic technology, to transfer developed technology to industries and end users by research activities and to diffuse photovoltaic systems by demonstration projects. This paper reviews long-term plan and status of technology R and D, and markets of photovoltaic. Some activities designed to promote collaboration with foreign countries are also introduced. (author). 14 refs., 3 figs., 3 tabs.

  16. Karlsruhe Nuclear Research Center. Research and development program 1991

    International Nuclear Information System (INIS)

    1990-01-01

    The R and D activities of the KfK are classified in 8 main research activities: 1) project nuclear fusion; 2) project pollutant mitigation in the environment; 3) solid state and materials research; 4) nuclear and elementary particle physics; 5) microtechnics e.g. X-ray lithography; 6) materials handling; 7) project nuclear safety research; 8) radioactive waste management. (orig.) [de

  17. Nuclear Research and Development Capabilities Needed to Support Future Growth

    Energy Technology Data Exchange (ETDEWEB)

    Wham, Robert M. [ORNL, P.O. Box 2008, Oak Ridge, TN 37831-6154 (United States); Kearns, Paul [Battelle Memorial Institute (United States); Marston, Ted [Marston Consulting (United States)

    2009-06-15

    The energy crisis looming before the United States can be resolved only by an approach that integrates a 'portfolio' of options. Nuclear energy, already an important element in the portfolio, should play an even more significant role in the future as the U.S. strives to attain energy independence and reduce carbon emissions. The DOE Office of Nuclear Energy asked Battelle Memorial Institute to obtain input from the commercial power generation industry on industry's vision for nuclear energy over the next 30-50 years. With this input, Battelle was asked to generate a set of research and development capabilities necessary for DOE to support the anticipated growth in nuclear power generation. This presentation, based on the report generated for the Office of Nuclear Energy, identifies the current and future nuclear research and development capabilities required to make this happen. The capabilities support: (1) continued, safe operation of the current fleet of nuclear plants; (2) the availability of a well qualified and trained workforce; (3) demonstration of the next generation nuclear plants; (4) development of a sustainable fuel cycle; (5) advanced technologies for maximizing resource utilization and minimization of waste and (6) advanced modeling and simulation for rapid and reliable development and deployment of new nuclear technologies. In order to assure these capabilities are made available, a Strategic Nuclear Energy Capability Initiative is proposed to provide the required resources during this critical period of time. (authors)

  18. Development of a new, rapid and sensitive HPTLC method for estimation of Milnacipran in bulk, formulation and compatibility study

    Directory of Open Access Journals (Sweden)

    Gautam Singhvi

    2017-05-01

    Full Text Available A simple, sensitive and rapid high performance thin layer chromatographic (HPTLC method has been developed and validated for quantitative determination of Milnacipran Hydrochloride (MIL in bulk and formulations. The chromatographic development was carried out on HPTLC plates precoated with silica gel 60 F254 using a mixture of acetonitrile, water and ammonia (6:0.6:1.6 (v/v/v as mobile phase. Detection was carried out densitometrically at 220 nm. The Rf value of drug was found to be 0.63 ± 0.02. The method was validated as per ICH guideline with respect to linearity, accuracy, precision, robustness etc. The calibration curve was found to be linear over a range of 100–1000 ng μL−1 with a regression coefficient of 0.999. The accuracy was found to be very high (99.12–100.87%. %RSD values for intra-day and inter-day variation were not more than 1.43. The method has demonstrated high sensitivity and specificity. The method was applied for compatibility studies also. The method is new, simple and economic for routine estimation of MIL in bulk, preformulation studies and pharmaceutical formulation to help the industries as well as researchers for their sensitive determination of MIL rapidly at low cost in routine analysis.

  19. Trends and Developments of Higher Education Research in Hong Kong: In Pursuit of a Cosmopolitan Vision

    Science.gov (United States)

    Lo, William Yat Wai; Ng, Felix Sai Kit

    2015-01-01

    With the processes of inter- and intranationalization, higher education in Hong Kong has been rapidly expanding in an effort to develop the city into a regional education hub. This article explores the trends and developments of higher education research (HER) in Hong Kong in the context of inter- and intranationalization. By drawing on the data…

  20. 75 FR 74026 - Biomass Research and Development Technical Advisory Committee

    Science.gov (United States)

    2010-11-30

    ... DEPARTMENT OF ENERGY Biomass Research and Development Technical Advisory Committee AGENCY.... SUMMARY: This notice announces an open meeting of the Biomass Research and Development Technical Advisory... participation. This notice announces the meeting of the Biomass Research and Development Technical Advisory...

  1. Research on the Application of Rapid Surveying and Mapping for Large Scare Topographic Map by Uav Aerial Photography System

    Science.gov (United States)

    Gao, Z.; Song, Y.; Li, C.; Zeng, F.; Wang, F.

    2017-08-01

    Rapid acquisition and processing method of large scale topographic map data, which relies on the Unmanned Aerial Vehicle (UAV) low-altitude aerial photogrammetry system, is studied in this paper, elaborating the main work flow. Key technologies of UAV photograph mapping is also studied, developing a rapid mapping system based on electronic plate mapping system, thus changing the traditional mapping mode and greatly improving the efficiency of the mapping. Production test and achievement precision evaluation of Digital Orth photo Map (DOM), Digital Line Graphic (DLG) and other digital production were carried out combined with the city basic topographic map update project, which provides a new techniques for large scale rapid surveying and has obvious technical advantage and good application prospect.

  2. Research and development in radiological protection

    International Nuclear Information System (INIS)

    Butragueno, J. L.; Villota, C.; Gutierrez, C.; Rodriguez, A.

    2004-01-01

    The objective of Radiological Protection is to guarantee that neither people, be they workers or members of the public, or the environment are exposed to radiological risks considered by society to be unacceptable. Among the various resources available to meet this objective is Research and Development (R and D), which is carried out in three areas: I. Radiological protection of persons: (a) knowledge of the biological effects of radiations, in order to determine the relationship that exists between radiation exposure dose and its effects on health; (b) the development of new personal dosimetry techniques in order to adapt to new situations, instrumental techniques and information management technologies allowing for better assessment of exposure dose; and (c) development of the principle of radiological protection optimisation (ALARA), which has been set up internationally as the fundamental principle on which radiological protection interventions are based. II. Assessment of environmental radiological impact, the objective of which is to assess the nature and magnitude of situations of exposure to ionising radiations as a result of the controlled or uncontrolled release of radioactive material to the environment, and III.Reduction of the radiological impact of radioactive wastes, the objective of which is to develop radioactive material and waste management techniques suitable for each situation, in order to reduce the risks associated with their definitive management or their release to the environment. Briefly described below are the strategic lines of R and D of the CSN, the Electricity Industry, Ciemat and Enresa in the aforementioned areas. (Author)

  3. Light-water reactor research and development

    International Nuclear Information System (INIS)

    1985-05-01

    This report on the national program of research and development on light water reactors is the second of two reports requested in 1982 by W. Kenneth Davis, Deputy Secretary of the Department of Energy. A first report, published in September 1983, treated the needs for safety-related R and D. In this second report, the Energy Research Advisory Board finds that, although many light water reactors are providing reliable and economic electricity, it appears unlikely that U.S. utilities will order additional reactors until the currently unacceptable economic risk, created by the regulatory climate and uncertain demand, is reduced. Thus it is unlikely that the private sector alone will fund major LWR design improvements. However, nuclear power will continue on its current course of expansion overseas. DOE participation is vitally needed to support the national interest in LWR technology. The report outlines R and D needs for a program to improve the safety, reliability, and economics of the present generation of plants; to develop evolutionary improved designs to be ready when needed; and to explore innovative longer-term concepts for deployment after the year 2000. The respective roles of government and the private sector are discussed

  4. New developments in transportation for research reactors

    Energy Technology Data Exchange (ETDEWEB)

    Mondanel, J.L. [Transnucleaire, F-75008 Paris (France)

    1998-07-01

    For more than 30 years, Transnucleaire has been performing safely a large number of national and international transports of radioactive material. Transnucleaire has also designed and supplied numerous packagings for all types of nuclear fuel cycle radioactive materials: for front-end and back-end products and for power and research reactors. Since the last meeting held in Bruges, Transnucleaire has been continuously involved in transportation activities for fresh and irradiated materials for research reactors. We are pleased to take the opportunity in this meeting to share with reactor operators, official bodies and other partners, the on-going developments in transportation and associated services. Special attention will be paid to the starting of transports of MTR spent fuel elements to the La Hague reprocessing plant where COGEMA offers reprocessing services on a long-term basis to reactors operators. Detailed information is provided on regulatory issues, which may affect transport activities: evolution of the regulations, real experiences of recent transportation and development of new packaging designs. Options and solutions will be proposed by Transnucleaire to improve the situation for continuation of national and international transports at an acceptable price whilst maintaining an ultimate level of safety (author)

  5. Is astronomical research appropriate for developing countries?

    Science.gov (United States)

    Snowden, Michael S.

    An unproductive 45-cm astronomical telescope, given by JICA (Japan) to Sri Lanka, raises general questions as to the reasons for unproductive pure science in developing countries. Before installation, site, maintenance, and scientific objectives were discussed. The facility was launched with a conference organised by the UN Office for Outer Space Affairs. Unfortunately, no research or significant education has resulted after four years. The annual operating cost is U.S. $5000 per year, including salary for a trainee, maintenance, and a modest promotional programme. Comparison with a similar installation in Auckland suggests lack of funding or technical competence do not explain the failure in Sri Lanka. The facility in New Zealand, on the roof of Auckland University's Physics Department, has a slightly smaller budget but has led to modest but useful research and teaching. Lack of financial backing and expertise are often blamed for weak science in developing countries, but examination shows most of these countries have adequately skilled people, and plenty of resources for religion and military. General lack of motivation for science appears to be the principal reason. This lack of interest and highly inefficient bureaucracies are common to scientifically unproductive countries. They mostly lack the cultural and philosophical base of the European Renaissance that motivate the pursuit of modern science, an activity that violates human preferences. There are excellent facilities (ESO, SAAO, Cerro Tololo, and GONG) in some of these same countries, when administered from the West.

  6. Book Sprint: A new model for rapid book authoring and content development

    International Nuclear Information System (INIS)

    Zennaro, M.; Canessa, E.; Fonda, C.; Belcher, M.; Flickenger, R.

    2007-01-01

    We discuss our experiences and successes with the new 'Book Sprint' methodology for use in rapid authoring and content development for technical books and documentation, using a distributed team and appropriate on-line collaborative technologies. A sprint begins by assembling a group of domain experts for a short period of time-intensive content creation. The outline, scope, and approximate length of the book are established, and key contributors are identified. This is followed by remote and distributed work over a period of a few months, focussing on the bulk of the book. The Sprint Book methodology has already been used in the 'Wireless Networking in the Developing World' and 'Bandwidth Optimization and Management' books. Both of these are freely available under a Creative Commons License. (author)

  7. Perancangan Aplikasi Presensi Dosen Realtime Dengan Metode Rapid Application Development (RAD Menggunakan Fingerprint Berbasis Web

    Directory of Open Access Journals (Sweden)

    Darma Setiawan Putra

    2018-05-01

    Full Text Available The fingerprint is one of the biometric methods which is can be used in the education field. Attendance monitoring system using fingerprint will make the leaders easily to monitor the attendance of the lecturer and to make decisions. The fingerprint attendance is used to easy students detecting quickly and accurately the lecturer in the classroom. This system aims to provide the lecturer status information, entry or exit for teaching when every lecturer performs a fingerprint scanning. This study uses rapid application development (RAD method to develop attendance system and involves the lecturer who have a teaching schedule in the current semester. To test the system, the lecturer was required to record the fingerprint in fingerprint machine. The result shows that the application of lecturer attendance in real time web-based can be a system provides the lecturers attendance information effectively and efficiently.

  8. Waste and Disposal: Research and Development

    Energy Technology Data Exchange (ETDEWEB)

    Neerdael, B.; Marivoet, J.; Put, M.; Van Iseghem, P

    2001-04-01

    This contribution to the annual report describes the main activities of the Waste and Disposal Department of the Belgian Nuclear Research Center SCK-CEN. Achievements in 2000 in three topical areas are reported on: performance assessments, waste forms/packages and near- and far field studies. Performance assessment calculations were made for the geological disposal of high-level and long-lived waste in a clay formation. An impact assessment was completed for the radium storage facility at Olen (Belgium). Geological data, pumping rates and various hydraulic parameters were collected in support of the development of a new version of the regional hydrogeological model for the Mol site. Research and Development on waste forms and waste packages included both in situ and laboratory tests. Main emphasis in 2000 was on corrosion studies on vitrified high-level waste, the investigation of localised corrosion of candidate container and overpack materials and the study of the effect of the degradation of cellulose containing waste as well as of bituminized waste on the solubility and the sorption of Pu and Am in geological disposal conditions in clay. With regard to near- and far-field studies, percolation and diffusion experiments to determine migration parameters of key radionuclides were continued. The electromigration technique was used to study the migration of redox sensitive species like uranium. In addition to laboratory experiments, several large-scale migration experiments were performed in the HADES Underground Research Laboratory. In 2000, the TRANCOM Project to study the influence of dissolved organic matter on radionuclide migration as well as the RESEAL project to demonstrate shaft sealing were continued.

  9. Waste and Disposal: Research and Development

    International Nuclear Information System (INIS)

    Neerdael, B.; Marivoet, J.; Put, M.; Van Iseghem, P.

    2001-01-01

    This contribution to the annual report describes the main activities of the Waste and Disposal Department of the Belgian Nuclear Research Center SCK-CEN. Achievements in 2000 in three topical areas are reported on: performance assessments, waste forms/packages and near- and far field studies. Performance assessment calculations were made for the geological disposal of high-level and long-lived waste in a clay formation. An impact assessment was completed for the radium storage facility at Olen (Belgium). Geological data, pumping rates and various hydraulic parameters were collected in support of the development of a new version of the regional hydrogeological model for the Mol site. Research and Development on waste forms and waste packages included both in situ and laboratory tests. Main emphasis in 2000 was on corrosion studies on vitrified high-level waste, the investigation of localised corrosion of candidate container and overpack materials and the study of the effect of the degradation of cellulose containing waste as well as of bituminized waste on the solubility and the sorption of Pu and Am in geological disposal conditions in clay. With regard to near- and far-field studies, percolation and diffusion experiments to determine migration parameters of key radionuclides were continued. The electromigration technique was used to study the migration of redox sensitive species like uranium. In addition to laboratory experiments, several large-scale migration experiments were performed in the HADES Underground Research Laboratory. In 2000, the TRANCOM Project to study the influence of dissolved organic matter on radionuclide migration as well as the RESEAL project to demonstrate shaft sealing were continued

  10. Rapid crown root development confers tolerance to zinc deficiency in rice

    Directory of Open Access Journals (Sweden)

    Amrit Kaur eNanda

    2016-03-01

    Full Text Available Zinc (Zn deficiency is one of the leading nutrient disorders in rice (Oryza sativa. Many studies have identified Zn efficient rice genotypes, but causal mechanisms for Zn deficiency tolerance remain poorly understood. Here we report a detailed study of the impact of Zn deficiency on crown root development of rice genotypes, differing in their tolerance to this stress. Zn deficiency delayed crown root development and plant biomass accumulation in both Zn efficient and inefficient genotypes, with the effects being much stronger in the latter. Zn efficient genotypes had developed new crown roots as early as three days after transplanting (DAT to a Zn deficient field and that was followed by a significant increase in total biomass by 7 DAT. Zn-inefficient genotypes developed few new crown roots and did not increase biomass during the first seven days following transplanting. This correlated with Zn efficient genotypes retranslocating a higher proportion of shoot Zn to their roots, compared to Zn inefficient genotypes. These latter genotypes were furthermore not efficient in utilizing the limited Zn for root development. Histological analyses indicated no anomalies in crown tissue of Zn-efficient or inefficient genotypes that would have suggested crown root emergence was impeded. We therefore conclude that the rate of crown root initiation was differentially affected by Zn deficiency between genotypes. Rapid crown root development, following transplanting, was identified as a main causative trait for tolerance to Zn deficiency and better Zn retranslocation from shoot to root was a key attribute of Zn-efficient genotypes.

  11. Monitoring Forest Change in Landscapes Under-Going Rapid Energy Development: Challenges and New Perspectives

    Directory of Open Access Journals (Sweden)

    Paul D. Pickell

    2014-07-01

    Full Text Available The accelerated development of energy resources around the world has substantially increased forest change related to oil and gas activities. In some cases, oil and gas activities are the primary catalyst of land-use change in forested landscapes. We discuss the challenges associated with characterizing ecological change related to energy resource development using North America as an exemplar. We synthesize the major impacts of energy development to forested ecosystems and offer new perspectives on how to detect and monitor anthropogenic disturbance during the Anthropocene. The disturbance of North American forests for energy development has resulted in persistent linear corridors, suppression of historical disturbance regimes, novel ecosystems, and the eradication of ecological memory. Characterizing anthropogenic disturbances using conventional patch-based disturbance measures will tend to underestimate the ecological impacts of energy development. Suitable indicators of anthropogenic impacts in forests should be derived from the integration of multi-scalar Earth observations. Relating these indicators to ecosystem condition will be a capstone in the progress toward monitoring forest change in landscapes undergoing rapid energy development.

  12. Development and Validation of a Lateral Flow Immunoassay for Rapid Detection of NDM-Producing Enterobacteriaceae

    Science.gov (United States)

    Boutal, Hervé; Naas, Thierry; Devilliers, Karine; Oueslati, Saoussen; Bernabeu, Sandrine; Simon, Stéphanie

    2017-01-01

    ABSTRACT The global spread of carbapenemase-producing Enterobacteriaceae (CPE) that are often resistant to most, if not all, classes of antibiotics is a major public health concern. The NDM-1 carbapenemase is among the most worrisome carbapenemases given its rapid worldwide spread. We have developed and evaluated a lateral flow immunoassay (LFIA) (called the NDM LFIA) for the rapid and reliable detection of NDM-like carbapenemase-producing Enterobacteriaceae from culture colonies. We evaluated the NDM LFIA using 175 reference enterobacterial isolates with characterized β-lactamase gene content and 74 nonduplicate consecutive carbapenem-resistant clinical isolates referred for expertise to the French National Reference Center (NRC) for Antibiotic Resistance during a 1-week period (in June 2016). The reference collection included 55 non-carbapenemase producers and 120 carbapenemase producers, including 27 NDM producers. All 27 NDM-like carbapenemase producers of the reference collection were correctly detected in less than 15 min by the NDM LFIA, including 22 strains producing NDM-1, 2 producing NDM-4, 1 producing NDM-5, 1 producing NDM-7, and 1 producing NDM-9. All non-NDM-1 producers gave a negative result with the NDM LFIA. No cross-reaction was observed with carbapenemases (VIM, IMP, NDM, KPC, and OXA-48-like), extended-spectrum β-lactamases (ESBLs) (TEM, SHV, and CTX-M), AmpCs (CMY-2, DHA-2, and ACC-1), and oxacillinases (OXA-1, -2, -9, and -10). Similarly, among the 74 referred nonduplicate consecutive clinical isolates, all 7 NDM-like producers were identified. Overall, the sensitivity and specificity of the assay were 100% for NDM-like carbapenemase detection with strains cultured on agar. The NDM LFIA was efficient, rapid, and easy to implement in the routine workflow of a clinical microbiology laboratory for the confirmation of NDM-like carbapenemase-producing Enterobacteriaceae. PMID:28404680

  13. Laboratory Directed Research and Development Program FY98

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, T. [ed.; Chartock, M.

    1999-02-05

    The Ernest Orlando Lawrence Berkeley National Laboratory (LBNL or Berkeley Lab) Laboratory Directed Research and Development Program FY 1998 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the supported projects and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The LBNL LDRD program is a critical tool for directing the Laboratory's forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for LBNL scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances LBNL's core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. All projects are work in forefront areas of science and technology. Areas eligible for support include the following: Advanced study of hypotheses, concepts, or innovative approaches to scientific or technical problems; Experiments and analyses directed toward ''proof of principle'' or early determination of the utility of new scientific ideas, technical concepts, or devices; and Conception and preliminary technical analyses of experimental facilities or devices.

  14. Aerodynamics support of research instrument development

    Science.gov (United States)

    Miller, L. Scott

    1990-09-01

    A new velocimetry system is currently being developed at NASA LaRC. The device, known as a Doppler global velocimeter (DGV), can record three velocity components within a plane simultaneously and in near real time. To make measurements the DGV, like many other velocimetry systems, relies on the scattering of light from numerous small particles in a flow field. The particles or seeds are illuminated by a sheet of laser light and viewed by two CCD cameras. The scattered light from the particles will have a frequency which is a function of the source laser light frequency, the viewing angle, and most importantly the seed velocities. By determining the scattered light intensity the velocity can be measured at all points within the light sheet simultaneously. Upon completion of DGV component construction and initial check out a series of tests in the Basic Aerodynamic Research (wind) Tunnel (BART) are scheduled to verify instrument operation and accuracy. If the results are satisfactory, application of the DGV to flight measurements on the F-18 High Alpha Research Vehicle (HARV) are planned. The DGV verification test in the BART facility will utilize a 75 degree swept delta wing model. A major task undertaken this summer included evaluation of previous results for this model. A specific series of tests matching exactly the previous tests and exploring new DGV capabilities were developed and suggested. Another task undertaken was to study DGV system installation possibilities in the F-18 HARV aircraft. In addition, a simple seeding system modification was developed and utilized to make Particle Imaging Velocimetry (PIV) measurements in the BART facility.

  15. Research skills development in higher education students

    Directory of Open Access Journals (Sweden)

    Tiziana Priede Bergamini

    2014-03-01

    Full Text Available This case study presents the development of a research project in a third-year undergraduate course, Family Business Administration. The research project aimed at promoting research skills in students. The authors formed working groups of no more than six students, and each group had to select an original research topic after conducting a literature review. Students were guided by the teachers and provided with initial reading materials, as well as an activity rubric specifying the minimum requirements of a scientific paper. The activity evaluation consisted of two parts, a written article (group assessment and an oral presentation (individual assessment. After the activity concluded, students were asked to answer an online satisfaction survey. Results showed students viewed the activity as positive and appreciated the chance to develop several competencies, including research skills. The authors conclude several objectives were achieved, including: familiarize students with scientific research; make sure students are cable of finding information through primary sources; have students apply the knowledge acquired during the course; promote responsibility in students; cultivate in students the capacity to summarize ideas and expose them in a reasoned way; have students learn from the experiences and knowledge of others; and develop in students the capacity to synthesize all that information. -------------------------- El desarrollo de la capacidad investigadora en estudiantes de educación superior Resumen  Este estudio de caso presenta el desarrollo de un proyecto de investigación en la asignatura “Administración de la Empresa Familiar” de tercer curso. El proyecto de investigación tenía como propósito fomentar de forma específica la capacidad investigadora de los alumnos. Se formaron grupos de trabajo de no más de seis estudiantes, y cada grupo tenía que seleccionar un tema de investigación original tras realizar una búsqueda de

  16. Investment in plant research and development bears fruit in China.

    Science.gov (United States)

    Chong, Kang; Xu, Zhihong

    2014-04-01

    Recent rapid progress in plant science and biotechnology in China demonstrates that China's stronger support for funding in plant research and development (R&D) has borne fruit. Chinese groups have contributed major advances in a range of fields, such as rice biology, plant hormone and developmental biology, genomics and evolution, plant genetics and epigenetics, as well as plant biotechnology. Strigolactone studies including those identifying its receptor and dissecting its complex structure and signaling are representative of the recent researches from China at the forefront of the field. These advances are attributable in large part to interdisciplinary studies among scientists from plant science, chemistry, bioinformatics, structural biology, and agronomy. The platforms provided by national facilities facilitate this collaboration. As well, efficient restructuring of the top-down organization of state programs and free exploration of scientists' interests have accelerated achievements by Chinese researchers. Here, we provide a general outline of China's progress in plant R&D to highlight fields in which Chinese research has made significant contributions.

  17. Rapid instrumental and separation methods for monitoring radionuclides in food and environmental samples. Final report on an IAEA co-ordinated research programme

    International Nuclear Information System (INIS)

    1995-01-01

    The Co-ordinated Research Programme (CRP) on Rapid Instrumental and Separation Methods for Monitoring Radionuclides in Food and Environmental Samples was established by the Agency following a Consultants' Meeting on the same topic, which was held 5-9 September 1988 in Vienna. It was completed in 1992. At various times during its course it encompassed 15 participants from 14 countries. The scope of work and objectives of the CRP were established at the Consultants' Meeting. It was agreed that the CRP should focus on the development of rapid methods for the determination of radionuclides in food and environmental samples during the intermediate and late post-accident phases. The rapid methods developed during the course of the CRP were intended to permit a timely and accurate determination of radionuclides at concentrations at least one order of magnitude below those specified for Derived Intervention Levels (DILs) for food by the WHO/FAO and the IAEA. Research Co-ordination meetings were held in Warsaw, Poland in September 1989 and in Vienna, Austria in 1991. Reports of the meetings are available from the Agency on Request. This document comprises copies of final reports from the participants and selected contributions presented by the participants at the meetings. The contributions were selected on the basis of being able to stand alone, without further explanation. Where there was an overlap in the information presented by a participant at both meetings, the most complete contribution was selected

  18. Rapid instrumental and separation methods for monitoring radionuclides in food and environmental samples. Final report on an IAEA co-ordinated research programme

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    The Co-ordinated Research Programme (CRP) on Rapid Instrumental and Separation Methods for Monitoring Radionuclides in Food and Environmental Samples was established by the Agency following a Consultants' Meeting on the same topic, which was held 5-9 September 1988 in Vienna. It was completed in 1992. At various times during its course it encompassed 15 participants from 14 countries. The scope of work and objectives of the CRP were established at the Consultants' Meeting. It was agreed that the CRP should focus on the development of rapid methods for the determination of radionuclides in food and environmental samples during the intermediate and late post-accident phases. The rapid methods developed during the course of the CRP were intended to permit a timely and accurate determination of radionuclides at concentrations at least one order of magnitude below those specified for Derived Intervention Levels (DILs) for food by the WHO/FAO and the IAEA. Research Co-ordination meetings were held in Warsaw, Poland in September 1989 and in Vienna, Austria in 1991. Reports of the meetings are available from the Agency on Request. This document comprises copies of final reports from the participants and selected contributions presented by the participants at the meetings. The contributions were selected on the basis of being able to stand alone, without further explanation. Where there was an overlap in the information presented by a participant at both meetings, the most complete contribution was selected.

  19. Developing a data sharing community for spinal cord injury research.

    Science.gov (United States)

    Callahan, Alison; Anderson, Kim D; Beattie, Michael S; Bixby, John L; Ferguson, Adam R; Fouad, Karim; Jakeman, Lyn B; Nielson, Jessica L; Popovich, Phillip G; Schwab, Jan M; Lemmon, Vance P

    2017-09-01

    The rapid growth in data sharing presents new opportunities across the spectrum of biomedical research. Global efforts are underway to develop practical guidance for implementation of data sharing and open data resources. These include the recent recommendation of 'FAIR Data Principles', which assert that if data is to have broad scientific value, then digital representations of that data should be Findable, Accessible, Interoperable and Reusable (FAIR). The spinal cord injury (SCI) research field has a long history of collaborative initiatives that include sharing of preclinical research models and outcome measures. In addition, new tools and resources are being developed by the SCI research community to enhance opportunities for data sharing and access. With this in mind, the National Institute of Neurological Disorders and Stroke (NINDS) at the National Institutes of Health (NIH) hosted a workshop on October 5-6, 2016 in Bethesda, MD, in collaboration with the Open Data Commons for Spinal Cord Injury (ODC-SCI) titled "Preclinical SCI Data: Creating a FAIR Share Community". Workshop invitees were nominated by the workshop steering committee (co-chairs: ARF and VPL; members: AC, KDA, MSB, KF, LBJ, PGP, JMS), to bring together junior and senior level experts including preclinical and basic SCI researchers from academia and industry, data science and bioinformatics experts, investigators with expertise in other neurological disease fields, clinical researchers, members of the SCI community, and program staff representing federal and private funding agencies. The workshop and ODC-SCI efforts were sponsored by the International Spinal Research Trust (ISRT), the Rick Hansen Institute, Wings for Life, the Craig H. Neilsen Foundation and NINDS. The number of attendees was limited to ensure active participation and feedback in small groups. The goals were to examine the current landscape for data sharing in SCI research and provide a path to its future. Below are

  20. Research on geochemical exploration in geotherm development

    International Nuclear Information System (INIS)

    Hirowatari, Kazuo; Imaizumi, Yukio; Koga, Akito; Iwanaga, Tatsuto.

    1987-01-01

    The decisive factor of geotherm development is to improve the exploration techniques. By effectively carrying out the selection of promising development spots and the decision of well drilling positions, the geotherm development exceeding existing energy sources becomes feasible. There have been many problems in conventional geotherm exploration such as the high cost and long work period, therefore, it was decided to advance the research on geochemical exploration techniques which are relatively simple and can be carried out with low cost. When the techniques of geochemistry are used, for example, in the case that there are hot springs or fumaroles, the temperature, origin, properties and so on of underground hot water reservoirs can be estimated from their chemical composition. The method of examining the mercury concentration in soil and soil air has been in practical use in the geothermal districts where the ground surface symptom lacks. This time, the method of investigation using radon, thoron and gamma ray as the exploration indices was newly studied. The index compositions for geochemical exploration, new exploration index compositions, the method of measurement, the basic investigation and on-the-spot investigation are reported. (Kako, I.)

  1. Fast Charging Electric Vehicle Research & Development Project

    Energy Technology Data Exchange (ETDEWEB)

    Heny, Michael

    2014-03-31

    The research and development project supported the engineering, design and implementation of on-road Electric Vehicle (“EV”) charging technologies. It included development of potential solutions for DC fast chargers (“DCFC”) capable of converting high voltage AC power to the DC power required by EVs. Additional development evaluated solutions related to the packaging of power electronic components and enclosure design, as well as for the design and evaluation of EV charging stations. Research compared different charging technologies to identify optimum applications in a municipal fleet. This project collected EV usage data and generated a report demonstrating that EVs, when supported by adequate charging infrastructure, are capable of replacing traditional internal combustion vehicles in many municipal applications. The project’s period of performance has demonstrated various methods of incorporating EVs into a municipal environment, and has identified three general categories for EV applications: Short Commute: Defined as EVs performing in limited duration, routine commutes. - Long Commute: Defined as tasks that require EVs to operate in longer daily mileage patterns. - Critical Needs: Defined as the need for EVs to be ready at every moment for indefinite periods. Together, the City of Charlottesville, VA (the “City”) and Aker Wade Power Technologies, LLC (“Aker Wade”) concluded that the EV has a viable position in many municipal fleets but with limited recommendation for use in Critical Needs applications such as Police fleets. The report also documented that, compared to internal combustion vehicles, BEVs have lower vehicle-related greenhouse gas (“GHG”) emissions and contribute to a reduction of air pollution in urban areas. The enhanced integration of EVs in a municipal fleet can result in reduced demand for imported oil and reduced municipal operating costs. The conclusions indicated in the project’s Engineering Report (see Attachment

  2. A STUDY ON THE INTRODUCTION OF BUS RAPID TRANSIT SYSTEM IN ASIAN DEVELOPING CITIES

    Directory of Open Access Journals (Sweden)

    Thaned SATIENNAM

    2006-01-01

    Full Text Available Bus Rapid Transit (BRT has increasingly become an attractive urban transit alternative in many Asian developing cities due to its cost-effective and flexible implementation. However, it still seems to be difficult to introduce BRT to these cities because almost all of their city structures have been developed under solely a road transport development city plan and weakness of land use control gives rise to many problems, such as urban sprawl, traffic congestion, and air pollution. The purpose of this study was to introduce several strategies to support BRT implementation in Asian developing cities, such as a strategy to appropriately integrate the paratransit system into BRT system as being a feeder along a BRT corridor to supply demand. These proposed strategies were evaluated by applying demand forecasting and emission models to the BRT project plan of Bangkok Metropolitan Administration (BMA in Thailand. It was demonstrated that the proposed strategies could effectively improve the BRT ridership, traffic conditions, and air pollution emission of the entire system in Bangkok. This study could be further extended to include strategy recommendation if a BRT system were to be introduced to other Asian developing cities.

  3. Development of a qPCR method to rapidly assess the function of NKT cells.

    Science.gov (United States)

    Sohn, Silke; Tiper, Irina; Japp, Emily; Sun, Wenji; Tkaczuk, Katherine; Webb, Tonya J

    2014-05-01

    NKT cells comprise a rare, but important subset of T cells which account for ~0.2% of the total circulating T cell population. NKT cells are known to have anti-tumor functions and rapidly produce high levels of cytokines following activation. Several clinical trials have sought to exploit the effector functions of NKT cells. While some studies have shown promise, NKT cells are approximately 50% lower in cancer patients compared to healthy donors of the same age and gender, thus limiting their therapeutic efficacy. These studies indicate that baseline levels of activation should be assessed before initiating an NKT cell based immunotherapeutic strategy. The goal of this study was to develop a sensitive method to rapidly assess NKT cell function. We utilized artificial antigen presenting cells in combination with qPCR in order to determine NKT cell function in peripheral blood mononuclear cells from healthy donors and breast cancer patients. We found that NKT cell activation can be detected by qPCR, but not by ELISA, in healthy donors as well as in breast cancer patients following four hour stimulation. This method utilizing CD1d-expressing aAPCs will enhance our knowledge of NKT cell biology and could potentially be used as a novel tool in adoptive immunotherapeutic strategies. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. Controlled precipitation for enhanced dissolution rate of flurbiprofen: development of rapidly disintegrating tablets.

    Science.gov (United States)

    Essa, Ebtessam A; Elmarakby, Amira O; Donia, Ahmed M A; El Maghraby, Gamal M

    2017-09-01

    The aim of this work was to investigate the potential of controlled precipitation of flurbiprofen on solid surface, in the presence or absence of hydrophilic polymers, as a tool for enhanced dissolution rate of the drug. The work was extended to develop rapidly disintegrated tablets. This strategy provides simple technique for dissolution enhancement of slowly dissolving drugs with high scaling up potential. Aerosil was dispersed in ethanolic solution of flurbiprofen in the presence and absence of hydrophilic polymers. Acidified water was added as antisolvent to produce controlled precipitation. The resultant particles were centrifuged and dried at ambient temperature before monitoring the dissolution pattern. The particles were also subjected to FTIR spectroscopic, X-ray diffraction and thermal analyses. The FTIR spectroscopy excluded any interaction between flurbiprofen and excipients. The thermal analysis reflected possible change in the crystalline structure and or crystal size of the drug after controlled precipitation in the presence of hydrophilic polymers. This was further confirmed by X-ray diffraction. The modulation in the crystalline structure and size was associated with a significant enhancement in the dissolution rate of flurbiprofen. Optimum formulations were successfully formulated as rapidly disintegrating tablet with subsequent fast dissolution. Precipitation on a large solid surface area is a promising strategy for enhanced dissolution rate with the presence of hydrophilic polymers during precipitation process improving the efficiency.

  5. [Development and evaluation of a rapid PCR detection kit for Ophiocordyceps sinensis].

    Science.gov (United States)

    Hou, Fei-Xia; Cao, Jing; Wang, Sha-Sha; Wang, Xi; Yuan, Yuan; Peng, Cheng; Wan, De-Guang; Guo, Jin-Lin

    2017-03-01

    Ophiocordyceps sinensis is a valuable traditional Chinese medicine. Due to resource shortage, expensive price and huge market demand, there are many adulterants of O. sinensis in markets. Therefore, it is necessary to establish a rapid and effective method for distinguishing O. sinensis. Based on the species-specific PCR of O. sinensis, this study developed a detection kit by optimizing the components and evaluated the specificity, detection limit, repeatability and shelf life of the kit. The results showed that when the quality of O. sinensis accounted for more than 1/200 of that mixture, it could be detected successfully. Moreover, only O. sinensis could be amplified and glowed bright green fluorescence under ultraviolet light. The kit was still in effect when it was placed at 37 ℃ for three days, which indicated that it was stable and effective for one year stored in 4 ℃. The kit in the same batch under different operation conditions, and in different batch under the same operation conditions gave the same result and accuracy, which showed good repeatability of the kit. It is simple, rapid and accurate to distinguish O. sinensis from its adulterants using the kit, and lays the foundation for commercialization of traditional Chinese medicine fast detection kit. Copyright© by the Chinese Pharmaceutical Association.

  6. Development of a rapid "fingerprinting" system for wine authenticity by mid-infrared spectroscopy.

    Science.gov (United States)

    Bevin, Christopher J; Fergusson, Allison J; Perry, Wade B; Janik, Leslie J; Cozzolino, Daniel

    2006-12-27

    This paper reports on the development of a rapid and simple method for red wine authenticity confirmation during transport and processing; namely, a wine "fingerprinting" system. When wine is transported between two sites, a sample is taken and a mid-infrared (MIR) spectrum is obtained. One hundred sixty-one (n = 161) samples of three main red wine varieties grown in Australia, Shiraz, Cabernet Sauvignon, and Merlot, were collected from six commercial wineries across Australia and scanned in transmission on two MIR spectrophotometers located at The Hardy Wine Company's main site at Reynella, South Australia (Foss WineScan FT 120) (926-5012 cm-1). A similarity index (SI) method was used as a tool to classify wine samples on the basis of their spectral data. The results showed that high rates of classification were obtained when wine samples scanned in different instruments were analyzed. The SI has been proven to provide an acceptable measurement for authentication of red wine integrity during transportation. In five of the six winery data sets, the SI correctly classified 98% of the wines. It was also observed that less than 1% of wines were misclassified between the different wineries investigated. Further studies are needed in order to test the applicability of the SI in a commercial situation and to evaluate its potential as a rapid quality control tool for routine use to authenticate wine samples during transport.

  7. Development of a fluorescence-based sensor for rapid diagnosis of cyanide exposure.

    Science.gov (United States)

    Jackson, Randy; Oda, Robert P; Bhandari, Raj K; Mahon, Sari B; Brenner, Matthew; Rockwood, Gary A; Logue, Brian A

    2014-02-04

    Although commonly known as a highly toxic chemical, cyanide is also an essential reagent for many industrial processes in areas such as mining, electroplating, and synthetic fiber production. The "heavy" use of cyanide in these industries, along with its necessary transportation, increases the possibility of human exposure. Because the onset of cyanide toxicity is fast, a rapid, sensitive, and accurate method for the diagnosis of cyanide exposure is necessary. Therefore, a field sensor for the diagnosis of cyanide exposure was developed based on the reaction of naphthalene dialdehyde, taurine, and cyanide, yielding a fluorescent β-isoindole. An integrated cyanide capture "apparatus", consisting of sample and cyanide capture chambers, allowed rapid separation of cyanide from blood samples. Rabbit whole blood was added to the sample chamber, acidified, and the HCN gas evolved was actively transferred through a stainless steel channel to the capture chamber containing a basic solution of naphthalene dialdehyde (NDA) and taurine. The overall analysis time (including the addition of the sample) was cyanide exposure. Most importantly, the sensor was 100% accurate in diagnosing cyanide poisoning for acutely exposed rabbits.

  8. Development of novel hybrid poly(l-lactide)/chitosan scaffolds using the rapid freeze prototyping technique

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, N; Chen, X B [Division of Biomedical Engineering, University of Saskatchewan, Saskatoon, Saskatchewan (Canada); Li, M G [Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, Saskatchewan (Canada); Cooper, D, E-mail: xbc719@mail.usask.ca [Department of Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, Saskatchewan (Canada)

    2011-09-15

    Engineered scaffolds have been shown to be critical to various tissue engineering applications. This paper presents the development of a novel three-dimensional scaffold made from a mixture of chitosan microspheres (CMs) and poly(l-lactide) by means of the rapid freeze prototyping (RFP) technique. The CMs were used to encapsulate bovine serum albumin (BSA) and improve the scaffold mechanical properties. Experiments to examine the BSA release were carried out; the BSA release could be controlled by adjusting the crosslink degree of the CMs and prolonged after the CMs were embedded into the PLLA scaffolds, while the examination of the mechanical properties of the scaffolds illustrates that they depend on the ratio of CMs to PLLA in the scaffolds as well as the cryogenic temperature used in the RFP fabrication process. The chemical characteristics of the PLLA/chitosan scaffolds were evaluated by Fourier transform infrared (FTIR) spectroscopy. The morphological and pore structure of the scaffolds were also examined by scanning electron microscopy and micro-tomography. The results obtained show that the scaffolds have higher porosity and enhanced pore size distribution compared to those fabricated by the dispensing-based rapid prototyping technique. This study demonstrates that the novel scaffolds have not only enhanced porous structure and mechanical properties but also showed the potential to preserve the bioactivities of the biomolecules and to control the biomolecule distribution and release rate.

  9. Penerapan Aplikasi Program Penjualan Dan Pembelian Menggunakan Model Rapid Application Development

    Directory of Open Access Journals (Sweden)

    Annisa Febriani

    2017-09-01

    Abstract The development of information technology at the moment quickly and rapidly, supported by one means namely computer. Of course the computer has been equipped with a particular application is used to help facilitate the work of the man to manage the data of an organization or company so that getting accurate results and according to needs. The results of the observations that have been made, showed a sales and purchase activities are still using manual systems, one of them at a clothing store. Starting from the data processing of the goods, the difficulty of checking stock, purchase transaction, sales transactions, as well as other data storage associated with all types of such activities, so that it could make a loss for the store owner, errors in the logging and less akuratnya the report is made. Judging from the large number of transactions done on clothing stores, required system information more quickly and accurately. Thus, the author makes the program architecture-based computer, use the Microsoft Visual Basic.net programming language and the MySQL database, so that the information and activities that occur can be done quickly and accurately. The methods used in making architecture the program using the model of Rapid Application Development (RAD. This RAD model is an adaptation of the waterfall model for high speed version of the development of each component of its software. Results achieved from the discussion of this theme is the form of the application program selling and buying the ready-made. In this case, the use of the application program is the best solution to solve the existing problems, as well as with the use of application programs can be reached by an activity which is effective and efficient in supporting that activity, especially for addressing the problem of the sale and purchase of.   Keywords: Sales Program, Purchasing Program.

  10. Development of a Rapid Salivary Proteomic Platform for Oral Feeding Readiness in the Preterm Newborn

    Directory of Open Access Journals (Sweden)

    Prarthana Khanna

    2017-12-01

    Full Text Available Oral feeding competency is a major determinant of length of stay in the neonatal intensive care unit. An infant must be able to consistently demonstrate the ability to take all required enteral nutrition by mouth before discharge home. Most infants born prematurely (<37 weeks will require days, if not weeks, to master this oral feeding competency skill. Inappropriately timed feeding attempts can lead to acute and long-term morbidities, prolonged hospitalizations, and increased health-care costs. Previously, a panel of five genes involved in essential developmental pathways including sensory integration (nephronophthisis 4, Plexin A1, hunger signaling [neuropeptide Y2 receptor (NPY2R, adenosine-monophosphate-activated protein kinase (AMPK], and facial development (wingless-type MMTV integration site family, member 3 required for oral feeding success were identified in neonatal saliva. This study aimed to translate these five transcriptomic biomarkers into a rapid proteomic platform to provide objective, real-time assessment of oral feeding skills, to better inform care, and to improve neonatal outcomes. Total protein was extracted from saliva of 10 feeding-successful and 10 feeding-unsuccessful infants matched for age, sex, and post-conceptional age. Development of immunoassays was attempted for five oral feeding biomarkers and two reference biomarkers (GAPDH and YWHAZ to normalize for starting protein concentrations. Normalized protein concentrations were correlated to both feeding status at time of sample collection and previously described gene expression profiles. Only the reference proteins and those involved in hunger signaling were detected in neonatal saliva at measurable levels. Expression patterns for NPY2R and AMPK correlated with the gene expression patterns previously seen between successful and unsuccessful feeders and predicted feeding outcome. Salivary proteins associated with hunger signaling are readily quantifiable in

  11. Clustering of smoking, alcohol drinking and cannabis use in adolescents in a rapidly developing country

    Directory of Open Access Journals (Sweden)

    Chiolero Arnaud

    2006-06-01

    Full Text Available Abstract Background Smoking, alcohol drinking and cannabis use ("risk behaviors" are often initiated at a young age but few epidemiological studies have assessed their joined prevalence in children in developing countries. This study aims at examining the joint prevalence of these behaviors in adolescents in the Seychelles, a rapidly developing country in the Indian Ocean. Methods Cross-sectional survey in a representative sample of secondary school students using an anonymous self-administered questionnaire (Global Youth Tobacco Survey. The questionnaire was completed by 1,321 (92% of 1,442 eligible students aged 11 to 17 years. Main variables of interest included smoking cigarettes on ≥1 day in the past 30 days; drinking any alcohol beverage on ≥1 day in the past 30 days and using cannabis at least once in the past 12 months. Results In boys and girls, respectively, prevalence (95% CI was 30% (26–34/21% (18–25 for smoking, 49% (45–54/48% (43–52 for drinking, and 17% (15–20/8% (6–10 for cannabis use. The prevalence of all these behaviors increased with age. Smokers were two times more likely than non-smokers to drink and nine times more likely to use cannabis. Drinkers were three times more likely than non-drinkers to smoke or to use cannabis. Comparison of observed versus expected frequencies of combination categories demonstrated clustering of these risk behaviors in students (P Conclusion Smoking, drinking and cannabis use were common and clustered among adolescents of a rapidly developing country. These findings stress the need for early and integrated prevention programs.

  12. Research and development for DOE environmental restoration and waste management

    International Nuclear Information System (INIS)

    Erickson, M.D.; Borys, S.S.; Bugielski, D.; Lien, S.C.T.; Hain, K.E.

    1991-01-01

    The US Department of Energy (DOE) recently consolidated its environmental restoration and waste management activities. Within that new organization, DOE has committed to support Research, Development, Demonstration, Testing and Evaluation (RDDT ampersand E) activities with the following objectives: rapidly advance beyond currently available technologies; provide solutions to key technical issues that will improve effectiveness, efficiency, and safety; and enhance DOE's ability to meet its 30-year compliance and cleanup goals. DOE has already supported a number of R ampersand D activities in this area and plans to continue that support in the future. DOE's Office of Technology Development is interested in eliciting broad participation from qualified organizations who can contribute to RDDT ampersand E activities. This presentation addresses the on-going and future R ampersand D, with an emphasis on the private sector activities. To focus private sector capabilities on the high-priority needs of DOE, a series of competitive solicitations was started in FY 1990. On May 1, 1990, on behalf of DOE's Office of Technology Development, Argonne National Laboratory issued a Request for Proposals that solicited proposals for research and development in the areas of (1) groundwater remediation, (2) soil remediation, (3) characterization of contamination and geological and hydrological features, and (4) containment of contaminated sites. In response to this solicitation, Argonne National Laboratory received 147 proposals. Fifteen of the proposals totaling $5.7 million were funded in FY 1990. The scope of work and evaluation criteria used in the procurement and the workscope of the resultant contracts are reviewed in this paper. The FY 1991 plans for competitive private sector research and development activities will also be presented at the conference. Funding levels, technical workscope, evaluation criteria, and schedule for the FY 1991 Request for Proposals will be detailed. 2

  13. Karlsruhe Nuclear Research Center. Research and development program 1992

    International Nuclear Information System (INIS)

    1991-01-01

    The KfK R and D activities are classified by ten point-of-main-effort projects: 1) low-pollution/low-waste methods, 2) environmental energy and mass transfers, 3) nuclear fusion, 4) nuclear saftey research, 5) radioactive waste management, 6) superconduction, 7) microtechnics, 8) materials handling, 9) materials and interfaces, 10) basic physical research. (orig.) [de

  14. Development of a Rapid Real-Time PCR Assay for Quantitation of Pneumocystis carinii f. sp. Carinii

    DEFF Research Database (Denmark)

    Larsen, Hans Henrik; Kovacs, Joseph A; Stock, Frida

    2002-01-01

    6 log values for standards containing > or =5 copies/tube. Application of the assay to a series of 10-fold dilutions of P. carinii organisms isolated from rat lung demonstrated that it was reproducibly quantitative over 5 log values (r = 0.99). The assay was applied to a recently reported in vitro...... axenic cultivation system for P. carinii and confirmed our microscopy findings that no organism multiplication had occurred during culture. For all cultures analyzed, QTD PCR assays showed a decrease in P. carinii DNA that exceeded the expected decrease due to dilution of the inoculum upon transfer......A method for reliable quantification of Pneumocystis carinii in research models of P. carinii pneumonia (PCP) that is more convenient and reproducible than microscopic enumeration of organisms would greatly facilitate investigations of this organism. We developed a rapid quantitative touchdown (QTD...

  15. Development of a Rapid Real-Time PCR Assay for Quantitation of Pneumocystis carinii f. sp. Carinii

    DEFF Research Database (Denmark)

    Larsen, Hans Henrik; Kovacs, Joseph A; Stock, Frida

    2002-01-01

    ) PCR assay for detecting P. carinii f. sp. carinii, the subspecies of P. carinii commonly used in research models of PCP. The assay was based on the single-copy dihydrofolate reductase gene and was able to detect r = 0.99) over...... 6 log values for standards containing > or =5 copies/tube. Application of the assay to a series of 10-fold dilutions of P. carinii organisms isolated from rat lung demonstrated that it was reproducibly quantitative over 5 log values (r = 0.99). The assay was applied to a recently reported in vitro....... In conclusion, a rapid, sensitive, and reproducible quantitative PCR assay for P. carinii f. sp. carinii has been developed and is applicable to in vivo as well as in vitro systems. The assay should prove useful for conducting studies in which quantification of organism burden or growth assessment is critical...

  16. India | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC-supported research in India has also focused on women's rights, security, and access ... Other IDRC employment-oriented research includes an initiative to help women ... enhance research quality at 43 public policy institutions in India.

  17. Search Results | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 1 - 10 of 9580 ... New partnership to support Ebola research teams ... population health research, and/or social science research in th ... Journal articles ... is a highly configurable open source electronic medical record system focused on ...

  18. Pakistan | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    For example, research in the Hindu Kush-Himalayas identified solutions to conserve soil ... This network specializes in applied research that connects economic and ... Groundbreaking research in Pakistan includes a study showing how the ...

  19. Development of quality assurance procedures for research and development

    Energy Technology Data Exchange (ETDEWEB)

    Nam, Ji Hee

    2000-12-01

    The complexity and the diversity of R and D project are increasing and the life cycle in science and technology is getting shorter. It is required that the results of research and development are subject to prove their objectivity. KAERI is performing complex and various R and D projects. It is necessary that the principle of R and D QA should be applicated to projects for the efficient conduct of R and D and the objective and fair evaluation of the results. So, such requirements as are commonly applicable and necessary, regardless of the type of project and the degree of risk, are selected and QA procedures are established therewith.

  20. Development of quality assurance procedures for research and development

    International Nuclear Information System (INIS)

    Nam, Ji Hee

    2000-12-01

    The complexity and the diversity of R and D project are increasing and the life cycle in science and technology is getting shorter. It is required that the results of research and development are subject to prove their objectivity. KAERI is performing complex and various R and D projects. It is necessary that the principle of R and D QA should be applicated to projects for the efficient conduct of R and D and the objective and fair evaluation of the results. So, such requirements as are commonly applicable and necessary, regardless of the type of project and the degree of risk, are selected and QA procedures are established therewith