WorldWideScience

Sample records for ranger district lewis

  1. 78 FR 38287 - Bitterroot National Forest, Darby Ranger District, Como Forest Health Project

    Science.gov (United States)

    2013-06-26

    ... DEPARTMENT OF AGRICULTURE Forest Service Bitterroot National Forest, Darby Ranger District, Como Forest Health Project AGENCY: Forest Service. ACTION: Notice; Correction. SUMMARY: The Department of Agriculture (USDA), Forest Service, Bitterroot National Forest, Darby Ranger District published a document in...

  2. 77 FR 23658 - Six Rivers National Forest, Gasquet Ranger District, California, The Smith River National...

    Science.gov (United States)

    2012-04-20

    ... National Forest, Gasquet Ranger District, California, The Smith River National Recreation Area [email protected] . Please insure that ``Smith River NRA Restoration and Motorized Travel Management'' occurs... UARs totaling 80 miles. The project encompasses the Smith River NRA and Gasquet Ranger District...

  3. 77 FR 58354 - Bend-Fort Rock Ranger District; Oregon; Withdrawal of Notice for Preparation of an Environmental...

    Science.gov (United States)

    2012-09-20

    ...-Fort Rock Ranger District; Oregon; Withdrawal of Notice for Preparation of an Environmental Impact... Administration, USDOT. ACTION: Notice of withdrawal. SUMMARY: The Bend-Fort Rock Ranger District and FHWA are..., Project Leader, Bend- Fort Rock Ranger District, 63095 Deschutes Market Road, Bend, OR 97701, phone 541...

  4. 75 FR 14419 - Camp Tatiyee Land Exchange on the Lakeside Ranger District of the Apache-Sitgreaves National...

    Science.gov (United States)

    2010-03-25

    ... Ranger, Lakeside Ranger District, Apache-Sitgreaves National Forests, c/o TEC Inc., 514 Via de la Valle... to other papers serving areas affected by this proposal: Tucson Citizen, Sierra Vista Herald, Nogales...

  5. 78 FR 45495 - Conejos Peak Ranger District, Rio Grande National Forest; Colorado; Cumbres Vegetation Management...

    Science.gov (United States)

    2013-07-29

    ..., Team Leader, San Luis Valley Publ ic Land Center, 1803 W. Hwy 160, Monte Vista, CO 81144. Commen ts may... the long-term. Responsible Official Conejos Peak District Ranger at 15571 County Road T5, La J ara, CO...

  6. 78 FR 15681 - Beaverhead-Deerlodge National Forest, Dillon Ranger District; Montana; Birch, Willow, Lost Project

    Science.gov (United States)

    2013-03-12

    ... higher susceptibility to insect and disease such as mountain pine beetle and blister rust. Responsible... documentation. Dated: March 5, 2013. Cole Mayn, Acting Dillon District Ranger. [FR Doc. 2013-05574 Filed 3-11-13...

  7. 75 FR 10456 - Kootenai National Forest, Fortine Ranger District, Montana; Galton Environmental Impact Statement

    Science.gov (United States)

    2010-03-08

    ...) Planning Areas (Wigwam, Grave, and Murphy) and the Fortine Ranger District portions of two (2) Planning... lawsuit settlement agreement with the Montana Wilderness Association commits the Forest Service to develop... travel planning for the Ten Lakes WSA. This project will also reduce hazardous fuels within and outside...

  8. 76 FR 76689 - Cibola National Forest, Mount Taylor Ranger District, NM, Mount Taylor Combined Exploratory Drilling

    Science.gov (United States)

    2011-12-08

    ... National Forest, Mount Taylor Ranger District, NM, Mount Taylor Combined Exploratory Drilling AGENCY... proposed action is to approve two Plans of Operations for exploratory uranium drilling on the Cibola... San Mateo. In total, there are up to 279 drill holes that would be drilled over a period not to exceed...

  9. 76 FR 22075 - Divide Ranger District, Rio Grande National Forest; CO; Black Mesa Vegetation Management Project

    Science.gov (United States)

    2011-04-20

    ... Ranger District, Rio Grande National Forest; CO; Black Mesa Vegetation Management Project AGENCY: Forest... Web site http://www.fs.usda.gov/riogrande under ``Land & Resource Management'', then ``Projects'' on... need for the Black Mesa Vegetation Management Project is move toward achieving long-term desired...

  10. 75 FR 8297 - Tongass National Forest, Thorne Bay Ranger District, Thorne Bay, AK

    Science.gov (United States)

    2010-02-24

    ..., Thorne Bay, AK AGENCY: Forest Service, USDA. ACTION: Cancellation of Notice of intent to prepare an... Roberts, Zone Planner, Thorne Bay Ranger District, Tongass National Forest, P.O. Box 19001, Thorne Bay, AK 99919, telephone: 907-828-3250. SUPPLEMENTARY INFORMATION: The 47,007-acre Kosciusko Project Area is...

  11. 75 FR 3195 - Ochoco National Forest, Lookout Mountain Ranger District; Oregon; Mill Creek; Allotment...

    Science.gov (United States)

    2010-01-20

    ...; Oregon; Mill Creek; Allotment Management Plans EIS AGENCY: Forest Service, USDA. ACTION: Notice of intent... allotments on the Lookout Mountain Ranger District. These four allotments are: Cox, Craig, Mill Creek, and..., Mill Creek and Old Dry Creek allotments. The responsible official will also decide how to mitigate...

  12. 75 FR 31418 - Intermountain Region, Payette National Forest, Council Ranger District; Idaho; Mill Creek-Council...

    Science.gov (United States)

    2010-06-03

    ... Ranger District; Idaho; Mill Creek--Council Mountain Landscape Restoration Project AGENCY: Forest Service... the Mill Creek--Council Mountain Landscape Restoration Project. The approximate 51,900 acre project area is located about two miles east of Council, Idaho. The Mill Creek--Council Mountain Landscape...

  13. Reassessment of Loblolly Pine Decline on the Oakmulgee Ranger District, Talladega National Forest, Alabama

    Science.gov (United States)

    Nolan J. Hess; William J. Otroana; John P. Jones; Arthur J. Goddard; Charles H. Walkinshaw

    1999-01-01

    Loblolly pine (Pinus taeda L.) decline has been a management concern on the Oakmulgee Ranger District since the 1960's. The symptoms include sparse crowns, reduced radial growth, deterioration of fine roots, decline, and mortality of loblolly pine by age 50.

  14. 78 FR 3879 - Ochoco National Forest, Paulina Ranger District; Oregon; Fox Canyon Cluster Allotment Management...

    Science.gov (United States)

    2013-01-17

    ... approximately 35 miles east of Prineville, south of Big Summit Prairie. The four allotments are Antler, Brush... other applicable legal requirements within the project area. Paulina Ranger District data indicates that throughout the project area, stream shade and bank stability do not meet Forest Plan standards. In addition...

  15. 78 FR 4377 - Idaho Panhandle National Forests, Coeur d'Alene River Ranger District, Shoshone County, ID...

    Science.gov (United States)

    2013-01-22

    ... Ranger District, Shoshone County, ID; Beaver Creek Project AGENCY: Forest Service, USDA. ACTION: Notice of intent to prepare an environmental impact statement. SUMMARY: The Forest Service will prepare an Environmental Impact Statement (EIS) on a proposal to accomplish vegetation management in the Beaver Creek...

  16. 75 FR 16728 - Beaver Creek Landscape Management Project, Ashland Ranger District, Custer National Forest...

    Science.gov (United States)

    2010-04-02

    ... DEPARTMENT OF AGRICULTURE Forest Service Beaver Creek Landscape Management Project, Ashland Ranger... manner that increases resiliency of the Beaver Creek Landscape Management Project area ecosystem to... requirements to require. The Beaver Creek Landscape Management Project includes treatments previously proposed...

  17. Energy Efficiency, Water Efficiency, and Renewable Energy Site Assessment: San Juan National Forest - Dolores Ranger District, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    Kandt, Alicen J. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Kiatreungwattana, Kosol [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2018-01-26

    This report summarizes the results from an energy efficiency, water efficiency, and renewable energy site assessment of the Dolores Ranger District in the San Juan National Forest in Colorado. A team led by the U.S. Department of Energy's National Renewable Energy Laboratory (NREL) conducted the assessment with United States Forest Service (USFS) personnel on August 16-17, 2016, as part of ongoing efforts by USFS to reduce energy and water use and implement renewable energy technologies. The assessment is approximately an American Society of Heating, Refrigerating, and Air-Conditioning Engineers Level 2 audit and meets Energy Independence and Security Act requirements.

  18. 76 FR 13344 - Beaver Creek Landscape Management Project, Ashland Ranger District, Custer National Forest...

    Science.gov (United States)

    2011-03-11

    ... DEPARTMENT OF AGRICULTURE Forest Service Beaver Creek Landscape Management Project, Ashland Ranger... Impact Statement for the Beaver Creek Landscape Management Project was published in the Federal Register... Responsible Official for the Beaver Creek Landscape Management Project. DATES: The Final Environmental Impact...

  19. Economic, social, and cultural aspects of livestock ranching on the Española and Canjilon Ranger Districts of the Santa Fe and Carson National Forests: a pilot study

    Science.gov (United States)

    Carol Raish; Alice M. McSweeney

    2003-01-01

    The ranches of northern New Mexico, composed of land and livestock, are integral components of family and community life. This pilot study examines current economic, social, and cultural aspects of livestock operations owned by ranchers with Federal grazing permits (permittees) on the Canjilon and Española Ranger Districts of the Santa Fe and Carson National...

  20. 75 FR 21577 - Rogue River-Siskiyou National Forest, Powers Ranger District, Coos County, OR; Eden Ridge Timber...

    Science.gov (United States)

    2010-04-26

    ... Plan, page C-39). Specifically for the Eden Ridge Timber Sales project, Needs include: Improvement of... District, Coos County, OR; Eden Ridge Timber Sales AGENCY: Forest Service, USDA. ACTION: Notice of intent... Forest's Probable Sale Quantity. The planning area is located approximately four (4) air miles southeast...

  1. 77 FR 2508 - Rogue River-Siskiyou National Forest, Powers Ranger District, Coos County, OR; Eden Ridge Timber...

    Science.gov (United States)

    2012-01-18

    ... Plan, page C-39). Specifically for the Eden Ridge Timber Sales project, Needs include: Improvement of... District, Coos County, OR; Eden Ridge Timber Sales AGENCY: Forest Service, USDA. ACTION: Corrected Notice of Intent to prepare an environmental impact statement for the Eden Ridge Timber Sales. The original...

  2. Exposure to hepatitis E virus, hepatitis A virus and Borrelia spp. infections in forest rangers from a single forest district in western Poland.

    Science.gov (United States)

    Bura, Maciej; Bukowska, Alicja; Michalak, Michał; Bura, Aleksandra; Nawrocki, Mariusz J; Karczewski, Marek; Mozer-Lisewska, Iwona

    2018-03-13

    Hepatitis E virus (HEV) infection is an emerging problem in developed countries. At least 2 zoonotic genotypes of the virus (HEV-3 and HEV-4) infect human beings. There are some data suggesting that forest rangers (FRs) can be at a higher risk of contact with HEV. The aim of this study was to assess the prevalence of HEV exposure markers in FRs from a single forest district in Greater Poland in relation to anti-HAV (hepatitis A virus) IgG, and anti-Borrelia spp. IgM and IgG antibodies. In total, 138 participants (48 FRs and 90 blood donors - BDs) were tested for anti-HEV IgM and IgG (EUROIMMUN Medizinische Labordiagnostika AG, Luebeck, Germany) and 96 individuals (48 FRs and 48 BDs) were tested for anti-HAV IgG (ARCHITECT immunoassays, Abbott Laboratories, Wiesbaden, Germany); anti-Borrelia IgM and IgG (EUROIMMUN kits) were assessed in FRs only. Anti-HEV markers were detected in 3 participants (2.2%; IgM in 1 FR, IgG in 2 BDs), less frequently than anti-HAV (16 out of 96 individuals, about 17%; FRs 19% vs BDs 15%) or anti-Borrelia antibodies (18 out of 48 individuals, 37.5%) (p < 0.0001 for both). Older study participants (≥45 years of age) were more frequently HAV-seropositive (29% vs 4% of the younger individuals; p = 0.0012). We failed to unequivocally prove HEV exposure in FRs. The HAV seroprevalence in this study paralleled the situation in the general population. Exposure to Borrelia spp. in FRs was common.

  3. ERA's Ranger uranium mine

    International Nuclear Information System (INIS)

    Davies, W.

    1997-01-01

    Energy Resource of Australia (ERA) is a public company with 68% of its shares owned by the Australian company North Limited. It is currently operating one major production centre - Ranger Mine which is 260 kilometres east of Darwin, extracting and selling uranium from the Ranger Mine in the Northern Territory to nuclear electricity utilities in Japan, South Korea, Europe and North America. The first drum of uranium oxide from Ranger was drummed in August 1981 and operations have continued since that time. ERA is also in the process of working towards obtaining approvals for the development of a second mine - Jabiluka which is located 20 kilometres north of Ranger. The leases of Ranger and Jabiluka adjoin. The Minister for the Environment has advised the Minister for Resources and Energy that there does not appear to be any environmental issue which would prevent the preferred Jabiluka proposal from proceeding. Consent for the development of ERA's preferred option for the development of Jabiluka is being sought from the Aboriginal Traditional Owners. Ranger is currently the third largest producing uranium mine in the world producing 4,237 tonnes of U 3 O 8 in the year to June 1997

  4. Allegheny County Park Rangers Outreach

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Launched in June 2015, the Allegheny County Park Rangers program reached over 48,000 people in its first year. Park Rangers interact with residents of all ages and...

  5. Ranger uranium project

    International Nuclear Information System (INIS)

    1979-01-01

    This agreement between the Commonwealth of Australia, Peko-Wallsend Operations Ltd., Electrolytic Zinc Company of Australasia Limited, and the Australian Atomic Energy Commission sets out articles under which the Ranger uranium project in the Northern Territory of Australia is to be operated

  6. Ranger uranium environmental enquiry

    International Nuclear Information System (INIS)

    1976-07-01

    The submission is divided into three sections. Section A considers the international implications of the development of uranium resources including economic and resource aspects and environmental and social aspects. Section B outlines the government's position on export controls over uranium and its effect on the introduction of nuclear power in Australia. Section C describes the licensing and regulatory functions that would be needed to monitor the environmental and health aspects of the Ranger project. (R.L.)

  7. Environmental auditing at Ranger

    International Nuclear Information System (INIS)

    Armstrong, A.; Reid, A.

    1989-01-01

    A preliminary external audit was carried out on three aspects of the Ranger Environmental Impact Statement (EIS), namely meteorological data, water release and water quality of releases. It assessed the accuracy of forecasts and predictive data statements against the actual environmental data obtained during operations, and concluded that impacts of the project were adequately described but inadequately quantified. The second state of the auditing is concerned with the assessment of the effectiveness of practices and procedures which are integrated into the ongoing environmental management program. 7 tabs. 2 figs

  8. Opportunities for Ranger and Jabiluka

    International Nuclear Information System (INIS)

    Oxnam, K.M.

    1999-01-01

    The processing of ore from ERA's Ranger mine will be completed before 2009, so the development of the Company's Jabiluka project is vital to its future. In order to achieve the Company's aim of utilising the Ranger mill to process the Jabiluka ore ERA is looking at innovative ways of furthering community relationships and responding to the needs of its major stakeholders, particularly the local Aboriginal landowners. The Jabiluka development has been a trigger for ERA to reconsider the way it does business in order to meet expectations of the community while maintaining financial viability

  9. 77 FR 18997 - Rim Lakes Forest Restoration Project; Apache-Sitgreavese National Forest, Black Mesa Ranger...

    Science.gov (United States)

    2012-03-29

    ... DEPARTMENT OF AGRICULTURE Forest Service Rim Lakes Forest Restoration Project; Apache-Sitgreavese National Forest, Black Mesa Ranger District, Coconino County, AZ AGENCY: Forest Service, USDA. ACTION: Notice of intent to prepare an environmental impact statement. SUMMARY: The U.S. Forest Service (FS) will...

  10. Financing the Ranger uranium project

    International Nuclear Information System (INIS)

    Hodge, S.J.; Miskelly, N.

    1983-01-01

    Construction of the Ranger uranium project located 230 km east of Darwin in the Northern Territory commenced in January 1979. Energy Resources of Australia Ltd was incorporated in February 1980 to acquire all the rights in the project. The total cost to ERA of these rights was $407 million. In October 1980 ERA'S cash requirements were estimated to be $553 million. Overseas participants (power utilities who had agreed to purchase uranium yellowcake under contract) arranged to take up 25% of the equity capital, Peko-Wallsend Ltd and EZ Industries Ltd were allotted 30.5% each and 14% was issued to Australian residents. The loan and equity financing arrangements required the successful resolution of many complex and interlocking factors, including technical and economic feasibility, agreement with aboriginal interests, compliance with Government policies and securing of sales contracts

  11. ERA`s Ranger uranium mine

    Energy Technology Data Exchange (ETDEWEB)

    Davies, W. [Energy Resources of Australia Ltd., Sydney, NSW (Australia)

    1997-12-31

    Energy Resource of Australia (ERA) is a public company with 68% of its shares owned by the Australian company North Limited. It is currently operating one major production centre - Ranger Mine which is 260 kilometres east of Darwin, extracting and selling uranium from the Ranger Mine in the Northern Territory to nuclear electricity utilities in Japan, South Korea, Europe and North America. The first drum of uranium oxide from Ranger was drummed in August 1981 and operations have continued since that time. ERA is also in the process of working towards obtaining approvals for the development of a second mine - Jabiluka which is located 20 kilometres north of Ranger. The leases of Ranger and Jabiluka adjoin. The Minister for the Environment has advised the Minister for Resources and Energy that there does not appear to be any environmental issue which would prevent the preferred Jabiluka proposal from proceeding. Consent for the development of ERA`s preferred option for the development of Jabiluka is being sought from the Aboriginal Traditional Owners. Ranger is currently the third largest producing uranium mine in the world producing 4,237 tonnes of U{sub 3}O{sub 8} in the year to June 1997.

  12. Wyndham Lewis

    OpenAIRE

    Maes-Jelinek, Hena

    2013-01-01

    Ours is a clownish age. If so the manYou be to understand it then you canScarcely be other than a man in an Iron MaskOr choose but choose a most invidious task. –Henceforth the voice you hear is the deep growl –The mask, if any, the notorious scowl –Of Enemy Number One. Wyndham Lewis was so prolific a writer that one sometimes tends to forget he was a painter in the first place, though his method owes much to the painter’s approach to his subject. His basic motive as a writer was to defend We...

  13. Lewy Body Dementia

    Science.gov (United States)

    Lewy body dementia Overview Lewy body dementia, also known as dementia with Lewy bodies, is the second most common type of progressive dementia after Alzheimer's disease dementia. Protein deposits, ...

  14. Lewy Body Dementia Association

    Science.gov (United States)

    ... Now events There are no upcoming events. Lewy Body Digest September 2017 Lewy Digest Caregiving as a ... and research, we support those affected by Lewy body dementias, their families and caregivers. We are dedicated ...

  15. The History of the 2nd Ranger Company

    National Research Council Canada - National Science Library

    Bond, Victor

    2003-01-01

    The purpose of this research project is to uncover the history of the 2nd Ranger Company and to determine the impact segregation had on the selection, training, and combat operations of the 2nd Ranger Company...

  16. 78 FR 48205 - Ranger Alternative Management, L.P. and Ranger Funds Investment Trust; Notice of Application

    Science.gov (United States)

    2013-08-07

    ... Alternative Management, L.P. and Ranger Funds Investment Trust; Notice of Application August 1, 2013. AGENCY... Management, L.P. (``Ranger'') and Ranger Funds Investment Trust (the ``Trust''). Summary of Application... (e) certain registered management investment companies and unit investment trusts outside of the same...

  17. Canadian Ranger Rifle: Human Factors Requirements Validation

    Science.gov (United States)

    2010-08-01

    index-eng.asp retrieved 9 February 2010 2 http://www.armee.forces.gc.ca/land-terre/cr-rc/history- histoire -eng.asp retrieved 9 February 2010 3 http... histoire -eng.asp Department of National Defence. (2010). Canadian Ranger Patrol (CRPG). Retrieved June 3, 2010, from http://www.army.forces.gc.ca

  18. Lewy Body Dementia Research

    Science.gov (United States)

    ... notices changes in at least one area of cognition, such as memory or language. Daytime Sleepiness is ... the field of Lewy body dementias. Memantine Improves Attention and Episodic Memory in Mild to Moderate Lewy ...

  19. Lewy Body Dementia Diagnosis

    Science.gov (United States)

    ... provide an experienced diagnostic team skilled in Lewy body dementia. A thorough dementia diagnostic evaluation includes physical ... a good way to benefit others with Lewy body dementia. Medications Medications are one of the most ...

  20. Lewy body dementias

    DEFF Research Database (Denmark)

    Løkkegaard, Annemette; Korbo, Lise

    2017-01-01

    Dementia with Lewy bodies and Parkinson disease dementia share the same pathophysiology. Together they are called Lewy body dementias and are the second most common type of dementia. Lewy body dementias receive little attention, and patients are often misdiagnosed, leading to less than ideal...

  1. The Ranger and Nabarlek mining agreements

    International Nuclear Information System (INIS)

    Gray, W.J.

    1980-01-01

    This article contains information about the content of the agreements which have been entered into between the Australian Government and the Northern Land Council in relation to the Ranger deposits in the Northern Territory and between the Government and Queensland Mines Limited and the N.L.C. in relation to the Nabarlek deposit. A statement by the Minister for Aboriginal Affairs on the impact of uranium mining on Northern Territory Aboriginals is included

  2. The Ranger project - a case study

    International Nuclear Information System (INIS)

    Young, R.I.

    1983-01-01

    Ranger Uranium Mines Pty. Ltd. operates an open pit mine and ore treatment plant in the Northern Territory designed to produce 3000 tonne/yr of U 3 O 8 from 3500 tonne/day of mill feed. The construction of the project was completed in 1981. Wright-Davy were the project managers and designers of the $270 million ore treatment plant and associated infrastructure. Details of project cost, staffing, project design and project systems are given

  3. Rehabilitation of the Ranger Mine Site

    International Nuclear Information System (INIS)

    East, J.; Uren, C.; Cull, R.; Curley, P.; Unger, C.

    1989-01-01

    Designs for long-lived waste rock piles in tropical Australia need to consider the climatic factors affecting erosion. Erosion trials on four plots at the Ranger waste rock dump demonstrate that some features of natural stable landforms such as slope morphogenetic variables and the size characteristics of aerial cover of resistive rock particles on the surface, can be sucessfully used in the design of the waste rock piles. Preliminary results indicate that the erosional stability of slopes can be enhanced by the use of concave surfaces. ills., diagrams

  4. 78 FR 69147 - Ranger Alternative Management, L.P. and Ranger Funds Investment Trust; Notice of Application

    Science.gov (United States)

    2013-11-18

    ...] Ranger Alternative Management, L.P. and Ranger Funds Investment Trust; Notice of Application November 12... Application: Applicants request an order that would permit (a) certain open-end management investment... Units; and (e) certain registered management investment companies and unit investment trusts outside of...

  5. Development of the Ranger uranium milling operations

    International Nuclear Information System (INIS)

    Baily, P.A.

    1982-01-01

    The development and operation of the Ranger uranium project is described. In 1969 Ranger discovered a uranium-bearing ore deposit in the Alligator Rivers Region of the Northern Territory of Australia. Extensive testwork on drill core samples proved the viability of the extraction of the uranium and a process flowsheet and plant design criteria were developed based on a conventional crushing, grinding, acid leach, C.C.D., solvent extraction circuit. Detailed design concentrated on plant layout, materials of construction, equipment vendor selection and process control. These factors required special attention because of the remote location of the mine and the high cost and difficulty in obtaining trained labour for such sites. Environmental considerations were key factors in design. The mine is located adjacent to a national park and has an average rainfall of 1,600 mm. No water or liquid effluents are to be released from the project area and thus water management is a key factor. Tailings are ponded in an impervious earth-rockfill dam

  6. Bernard Lewis: An Appreciation.

    Science.gov (United States)

    Humphreys, R. Stephen

    1990-01-01

    Discusses the career and publications of Bernard Lewis, a noted scholar in the field of Middle-Eastern studies and Islamic history. Traces the history of Western-based Islamic historiography. Examines Lewis' interpretation of Islamic history, outlining his political and social views. (RW)

  7. Lewis Acidic Ionic Liquids.

    Science.gov (United States)

    Brown, Lucy C; Hogg, James M; Swadźba-Kwaśny, Małgorzata

    2017-08-21

    Until very recently, the term Lewis acidic ionic liquids (ILs) was nearly synonymous with halometallate ILs, with a strong focus on chloroaluminate(III) systems. The first part of this review covers the historical context in which these were developed, speciation of a range of halometallate ionic liquids, attempts to quantify their Lewis acidity, and selected recent applications: in industrial alkylation processes, in supported systems (SILPs/SCILLs) and in inorganic synthesis. In the last decade, interesting alternatives to halometallate ILs have emerged, which can be divided into two sub-sections: (1) liquid coordination complexes (LCCs), still based on halometallate species, but less expensive and more diverse than halometallate ionic liquids, and (2) ILs with main-group Lewis acidic cations. The two following sections cover these new liquid Lewis acids, also highlighting speciation studies, Lewis acidity measurements, and applications.

  8. Hydrology of Ranger land application area

    International Nuclear Information System (INIS)

    McQuade, C.V.

    1992-01-01

    In 1984 Ranger Uranium Mines (RUM) began assessing the technique of water treatment by land application as a means of reducing the volume of stored water within the Restricted Release Zone. Knowledge of the hydrological characteristics of the treatment site is necessary for optimal day to day and season to season operation of the system and as an input into the assessment of the long-term viability of the site. This paper provides background information on the hydrological requirements for a water treatment site, describes the RUM's water treatment by land application system and summarises the operational statistics and current hydrological knowledge of the site. The general groundwater hydrology of the area comprises a surface soil aquifer overlying a semi-confined aquifer. Drainage of the surface aquifer follows the surface topography along the sandy clays. Vertical permeability ranges between 3 and 12 times greater than horizontal permeability. 7 refs., 2 tabs., 4 figs

  9. Lewy body dementias

    DEFF Research Database (Denmark)

    Løkkegaard, Annemette; Korbo, Lise

    2017-01-01

    Dementia with Lewy bodies and Parkinson disease dementia share the same pathophysiology. Together they are called Lewy body dementias and are the second most common type of dementia. Lewy body dementias receive little attention, and patients are often misdiagnosed, leading to less than ideal...... management. In this article, diagnostic criteria combined with imaging and other biomarkers as well as current treatment recommendations are summarized, and some of the challenges for the future are outlined. Refinement of diagnosis and clarification of the pathogenesis are required in search for disease...

  10. Lewy Body Disease

    Science.gov (United States)

    ... range of symptoms, including Changes in alertness and attention Hallucinations Problems with movement and posture Muscle stiffness Confusion Loss of memory Lewy body disease can be hard to diagnose, ...

  11. Water management at Ranger Uranium Mine

    International Nuclear Information System (INIS)

    Carron, K.J.

    1989-01-01

    The water management system at the Ranger Uranium Mine is described. Any water that may have come into contact with material containing more than 0.02% uranium must be retained within the Restricted Release zone (RRZ) from which no water may be released except under specified conditions and with the written approval of the Northern Territory supervising authority. The RRS contains the tailings dam, the mine pit and retention ponds 2 and 3. Outside the RR2, retention ponds 1 and 4 act as silt traps, allowing sediment to settle out prior to water discharge. The Office of Supervising Scientist has developed receiving waters quality standards for Magela Creek which are given in a table. There have now been established sufficient regulatory criteria to allow the release of waste water directly to Magela Creek without compromising the environment. Consideration of releases has been confined to the comparatively good quality run-off waters in the RRZ and no release of the more contaminated process and tailings water stream is contemplated

  12. Rangers Lead the Way: The Vision of General Creighton W. Abrams

    National Research Council Canada - National Science Library

    Woods, Kent

    2003-01-01

    .... A restoration which was key to the Army emerging from its post Viet Nam period of decline. The values and standards incorporated in the Ranger Battalions were promulgated throughout the rest of the Army by Rangers returning...

  13. Rejoinder to Lewis

    Directory of Open Access Journals (Sweden)

    Ashton Anderson

    2015-01-01

    Full Text Available In a response to our article “Political Ideology and Racial Preferences in Online Dating,” Kevin Lewis (2015 has raised concerns about various aspects of our analysis of user behavior on a national online dating site. The core of Lewis’ critique is that we do not report specifics of the sample, the website, and the analysis. Lewis also details numerous smaller points with respect to details of the analysis. The goal of this response is not to reply to every point that Lewis makes. As with any research project, our design decisions require tradeoffs, and readers should evaluate the evidence on their own. Rather, we use this space to make broader points about the general value for sociology of research using online data and how such research should be practiced.

  14. Ferrocene-based Lewis acids and Lewis pairs: Synthesis and ...

    Indian Academy of Sciences (India)

    The design and synthesis of molecules containing non-interacting Lewis base and Lewis acid groups. [Frustrated Lewis pairs (FLP's)] have received intense attention due to their potential applications in the area of molecular catalysis.1–3. For example,. Stephen's and co-workers have demonstrated that the unquenched ...

  15. Symptoms of Lewy Body Dementia

    Science.gov (United States)

    ... the fight against LBD! Donate Symptoms Lewy body dementia (LBD) has variable presentations that include cognitive difficulties ... wake cycle alterations. Cognitive impairment in Lewy body dementia (LBD) is often misdiagnosed as Alzheimer’s disease (AD). ...

  16. Distance Learning With NASA Lewis Research Center's Learning Technologies Project

    Science.gov (United States)

    Petersen, Ruth

    1998-01-01

    The NASA Lewis Research Center's Learning Technologies Project (LTP) has responded to requests from local school district technology coordinators to provide content for videoconferencing workshops. Over the past year we have offered three teacher professional development workshops that showcase NASA Lewis-developed educational products and NASA educational Internet sites. In order to determine the direction of our involvement with distance learning, the LTP staff conducted a survey of 500 U.S. schools. We received responses from 72 schools that either currently use distance learning or will be using distance learning in 98-99 school year. The results of the survey are summarized in the article. In addition, the article provides information on distance learners, distance learning technologies, and the NASA Lewis LTP videoconferencing workshops. The LTP staff will continue to offer teacher development workshops through videoconferencing during the 98-99 school year. We hope to add workshops on new educational products as they are developed at NASA Lewis.

  17. Lewis, Prof. Gilbert Newton

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Lewis, Prof. Gilbert Newton. Date of birth: 25 October 1875. Date of death: 24 March 1946. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year meeting of the Academy will be held ...

  18. Frustrated Lewis Pairs

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 19; Issue 11. Frustrated Lewis Pairs : Enabling via inability. Sanjoy Mukherjee ... Author Affiliations. Sanjoy Mukherjee Pakkirisamy Thilagar1. Department of Inorgainic and Physical Chemistry Indian Institute of Science Bangalore 560 012, India.

  19. Mighty Morphin Power Ranger Play: Research and Reality.

    Science.gov (United States)

    Crosser, Sandra

    1995-01-01

    Explores the question of whether or not Mighty Morphin Power Rangers-type aggressive play is developmentally appropriate for the early childhood classroom. Compares results from research in child development to the reality of television programming, highlighting the relationship between television violence and children's aggressive behavior. (AA)

  20. Lewy Body Digest eNewsletter

    Science.gov (United States)

    ... resources Join the fight against LBD! Donate Lewy Digest Click here to subscribe today to receive regular ... research in Lewy body dementia. April 2018 Lewy Digest Month of Compassion Caregiver Spotlight Research Centers of ...

  1. Ranger project starts-up amid doubts and optimism

    International Nuclear Information System (INIS)

    Gomez, B.

    1982-01-01

    After two and a half years construction and commissioning, the Ranger uranium project was officially opened on November 20, 1981. It was later closed for four days in connection with possible breaches of environmental regulations owing to the appearance of islands in the tailings dam. Contracts currently held represent a production commitment slightly in excess of the design capacity of the plant for the next decade

  2. Natural resources youth training program (NRYTP), resource rangers 2010

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-09-15

    In 2010, for a second year, the natural resources youth training program (NRYTP) was developed in northern Manitoba thanks to Manitoba Keewatinowi Okimakanak Inc. (MKO) and the collaboration of 42 sponsors. 16 aboriginal youth representing six northern communities took part in the five-week program located at the Egg Lake camp. The objective was to provide these resources rangers with knowledge and training in the most widespread resource sectors in northern Manitoba, including mining, forestry and hydropower. Trainers and experts provided by industry partners offered training sessions, hands-on work experience and other activities to help resource rangers to acquire a better understanding of the employability in this field in the northern region and the knowledge and skills the resource-based careers require. Life and professional skills training was given by the camp staff and local professionals. On-site elders and cultural events also allowed the integration of a northern Cree cultural component. Three staff members, a cook and elders assisted daily the resource rangers. Many improvements and refinements have been made since the success of the 2009 program, including the involvement of a larger number of communities, program contributors and program graduates. The program length has doubled and the number of jobs created has increased, important cultural aspects were introduced and the overall expenses were reduced.

  3. On the axisymmetric Lewis metric

    International Nuclear Information System (INIS)

    Gariel, J.; Marcilhacy, G.

    2001-03-01

    We obtain the general solution of the axisymmetric stationary vacuum spacetime of Lewis. After precising the fundamental hypothesis of Lewis, we demonstrate that the solution is related to an arbitrary harmonic function. Formally, these solutions are the same as for the corresponding cylindrically symmetric case, and can be classified in a similar way. Furthermore, the interpretation, in the cylindrically symmetric system, of the field equations as decribing the motion of a classical particle in a central force field is still valid. (author)

  4. Occupational health and safety inspection of the Ranger Uranium Mine

    International Nuclear Information System (INIS)

    Rosen, R.

    1987-04-01

    The principal purpose of the inspection was to assess all aspects of occupational health and safety at the Ranger Uranium Mine. A major objective was to identify actual and potential hazards under normal and abnormal conditions, particularly in relation to those topics about which the unions had expressed some concern. An assessment was made of current safety policies, procedures and practices at the site; and, as far as practicable, those tasks which involved risks to workers were identified. The results and recommendations of the inspection are contained in this report

  5. The economic impact on Aboriginal communities of the Ranger Project: 1979-1985

    International Nuclear Information System (INIS)

    O'Faircheallaigh, C.

    1986-01-01

    What are the benefits generated for Aboriginal people by mining projects like the Ranger Project? Are these projects likely to fulfill the expectations of Aborigines who support the controlled exploitation of mineral resources on their land? This article examines the economic impact of the Ranger uranium project on Aboriginal people. Its principal aim is to provide detailed information on the use of royalty-related payments made to traditional owners as a result of Ranger's operations, and the consequent employment, training and social service opportunities for Aborigines

  6. Barack Obama, John Lewis, and the Legacy of the Civil Rights Struggle

    Directory of Open Access Journals (Sweden)

    Glenn T. Eskew

    2012-01-01

    Full Text Available The watershed election in 2008 of Barack Obama as the first President of the United States to have African ancestry resulted from the life work of such civil rights activists as U.S. Congressman John Lewis. Born on a sharecropper’s farm in 1940, the African American Lewis grew up in segregated Alabama. As a college student in Nashville, he joined the sit-in protests and volunteered for the original Freedom Ride in 1961. He was elected chairman of the Student Nonviolent Coordinating Committee, becoming the youngest speaker at the March on Washington in 1963. The radical shift to Black ultimately forced Lewis out of SNCC. Consequently Lewis capitalized on the Voting Rights Act of 1965, turned his attentions to voter registration campaigns, and continued working within the system. In 1986 he won election to the U.S. House of Representatives to represent Atlanta’s Fifth Congressional District, a seat he continues to hold today.

  7. Electron-Muon Ranger: performance in the MICE Muon Beam

    CERN Document Server

    Adams, D.; Vankova-Kirilova, G.; Bertoni, R.; Bonesini, M.; Chignoli, F.; Mazza, R.; Palladino, V.; de Bari, A.; Cecchet, G.; Capponi, M.; Iaciofano, A.; Orestano, D.; Pastore, F.; Tortora, L.; Kuno, Y.; Sakamoto, H.; Ishimoto, S.; Filthaut, F.; Hansen, O.M.; Ramberger, S.; Vretenar, M.; Asfandiyarov, R.; Bene, P.; Blondel, A.; Cadoux, F.; Debieux, S.; Drielsma, F.; Graulich, J.S.; Husi, C.; Karadzhov, Y.; Masciocchi, F.; Nicola, L.; Messomo, E.Noah; Rothenfusser, K.; Sandstrom, R.; Wisting, H.; Charnley, G.; Collomb, N.; Gallagher, A.; Grant, A.; Griffiths, S.; Hartnett, T.; Martlew, B.; Moss, A.; Muir, A.; Mullacrane, I.; Oates, A.; Owens, P.; Stokes, G.; Warburton, P.; White, C.; Adams, D.; Barclay, P.; Bayliss, V.; Bradshaw, T.W.; Courthold, M.; Francis, V.; Fry, L.; Hayler, T.; Hills, M.; Lintern, A.; Macwaters, C.; Nichols, A.; Preece, R.; Ricciardi, S.; Rogers, C.; Stanley, T.; Tarrant, J.; Watson, S.; Wilson, A.; Bayes, R.; Nugent, J.C.; Soler, F.J.P.; Cooke, P.; Gamet, R.; Alekou, A.; Apollonio, M.; Barber, G.; Colling, D.; Dobbs, A.; Dornan, P.; Hunt, C.; Lagrange, J-B.; Long, K.; Martyniak, J.; Middleton, S.; Pasternak, J.; Santos, E.; Savidge, T.; Uchida, M.A.; Blackmore, V.J.; Carlisle, T.; Cobb, J.H.; Lau, W.; Rayner, M.A.; Tunnell, C.D.; Booth, C.N.; Hodgson, P.; Langlands, J.; Nicholson, R.; Overton, E.; Robinson, M.; Smith, P.J.; Dick, A.; Ronald, K.; Speirs, D.; Whyte, C.G.; Young, A.; Boyd, S.; Franchini, P.; Greis, J.; Pidcott, C.; Taylor, I.; Gardener, R.; Kyberd, P.; Littlefield, M.; Nebrensky, J.J.; Bross, A.D.; Fitzpatrick, T.; Leonova, M.; Moretti, A.; Neuffer, D.; Popovic, M.; Rubinov, P.; Rucinski, R.; Roberts, T.J.; Bowring, D.; DeMello, A.; Gourlay, S.; Li, D.; Prestemon, S.; Virostek, S.; Zisman, M.; Hanlet, P.; Kafka, G.; Kaplan, D.M.; Rajaram, D.; Snopok, P.; Torun, Y.; Blot, S.; Kim, Y.K.; Bravar, U.; Onel, Y.; Cremaldi, L.M.; Hart, T.L.; Luo, T.; Sanders, D.A.; Summers, D.J.; Cline, D.; Yang, X.; Coney, L.; Hanson, G.G.; Heidt, C.

    2015-12-16

    The Muon Ionization Cooling Experiment (MICE) will perform a detailed study of ionization cooling to evaluate the feasibility of the technique. To carry out this program, MICE requires an efficient particle-identification (PID) system to identify muons. The Electron-Muon Ranger (EMR) is a fully-active tracking-calorimeter that forms part of the PID system and tags muons that traverse the cooling channel without decaying. The detector is capable of identifying electrons with an efficiency of 98.6%, providing a purity for the MICE beam that exceeds 99.8%. The EMR also proved to be a powerful tool for the reconstruction of muon momenta in the range 100-280 MeV/$c$.

  8. Radioactive dust concentration around the Ranger uranium mine

    International Nuclear Information System (INIS)

    Kavasnicka, Jiri.

    1988-07-01

    Environmental dust sampling and wind direction/velocity monitory were carried out between July and November 1987 at five points around the Ranger Uranium Mines project near Jabiru, Northern Territory. The measured radioactive dust alpha activities in the air were used to calculate the radioactive dust source-term and develop a site-specific air dispersion model which takes the depletion of the dust plume into account. The above model was used to estimate the effective committed dose equivalent as 15 μSv/year to children in Jabiru East. This corresponds to an increase of 2.6 x 10 -4 Bq. m -3 in the annual average dust alpha activity above the natural background. The dose to the children in Jabiru is about 5 μSv/year, so that the critical group of the public is in Jabiru East. 12 refs., 11 tabs., 2 maps

  9. Electron-muon ranger: performance in the MICE muon beam

    International Nuclear Information System (INIS)

    Adams, D.; Barclay, P.; Bayliss, V.; Bradshaw, T.W.; Alekou, A.; Apollonio, M.; Barber, G.; Asfandiyarov, R.; Bene, P.; Blondel, A.; De Bari, A.; Bayes, R.; Bertoni, R.; Bonesini, M.; Blackmore, V.J.; Blot, S.; Bogomilov, M.; Booth, C.N.; Bowring, D.; Boyd, S.

    2015-01-01

    The Muon Ionization Cooling Experiment (MICE) will perform a detailed study of ionization cooling to evaluate the feasibility of the technique. To carry out this program, MICE requires an efficient particle-identification (PID) system to identify muons. The Electron-Muon Ranger (EMR) is a fully-active tracking-calorimeter that forms part of the PID system and tags muons that traverse the cooling channel without decaying. The detector is capable of identifying electrons with an efficiency of 98.6%, providing a purity for the MICE beam that exceeds 99.8%. The EMR also proved to be a powerful tool for the reconstruction of muon momenta in the range 100–280 MeV/c

  10. Lewis and Clark as Naturalists.

    Science.gov (United States)

    Smithsonian Institution, Washington, DC. National Museum of Natural History.

    Intended for use in elementary and high school education, this Web site includes a teacher's guide and three lesson plans. The site contains images of museum specimens, scientific drawings, and field photos of the plant and animal species observed by Meriwether Lewis and William Clark, along with journal excerpts, historical notes, and references…

  11. Are ranger patrols effective in reducing poaching-related threats within protected areas?

    Science.gov (United States)

    Moore, Jennnifer F.; Mulindahabi, Felix; Masozera, Michel K.; Nichols, James; Hines, James; Turikunkiko, Ezechiel; Oli, Madan K.

    2018-01-01

    Poaching is one of the greatest threats to wildlife conservation world-wide. However, the spatial and temporal patterns of poaching activities within protected areas, and the effectiveness of ranger patrols and ranger posts in mitigating these threats, are relatively unknown.We used 10 years (2006–2015) of ranger-based monitoring data and dynamic multi-season occupancy models to quantify poaching-related threats, to examine factors influencing the spatio-temporal dynamics of these threats and to test the efficiency of management actions to combat poaching in Nyungwe National Park (NNP), Rwanda.The probability of occurrence of poaching-related threats was highest at lower elevations (1,801–2,200 m), especially in areas that were close to roads and tourist trails; conversely, occurrence probability was lowest at high elevation sites (2,601–3,000 m), and near the park boundary and ranger posts. The number of ranger patrols substantially increased the probability that poaching-related threats disappear at a site if threats were originally present (i.e. probability of extinction of threats). Without ranger visits, the annual probability of extinction of poaching-related threats was an estimated 7%; this probability would increase to 20% and 57% with 20 and 50 ranger visits per year, respectively.Our results suggest that poaching-related threats can be effectively reduced in NNP by adding ranger posts in areas where they do not currently exist, and by increasing the number of patrols to sites where the probability of poaching activities is high.Synthesis and applications. Our application of dynamic occupancy models to predict the probability of presence of poaching-related threats is novel, and explicitly considers imperfect detection of illegal activities. Based on the modelled relationships, we identify areas that are most vulnerable to poaching, and offer insights regarding how ranger patrols can be optimally deployed to reduce poaching-related threats and

  12. Range Riders and Game Wardens: A Brief History of Fort Bragg’s Forest Ranger Program

    Science.gov (United States)

    2006-07-01

    Estelle Rowland and Evelyn Ellington. Infor- mal interviews were conducted with family members of former rangers, Myra Mort Hanni , Elizabeth McPherson, Dun...worked under the command of the sergeant whose family resided in the main house. As Myra Mott Hanni , daughter of 1920s ranger Sergeant John Sidney Mott...above as well as by Myra Mott Hanni who retains a photograph of her father standing next to a confiscated still. Wilson recalls finding stills on the

  13. Groundwater regimes and isotopic studies, Ranger mine area, Northern Territory

    Energy Technology Data Exchange (ETDEWEB)

    Ahmad, M; Green, D C

    1986-12-01

    Three types of groundwater occur in the area of the Ranger mine. Type A groundwater occurs in the loose sands and gravels occupying the present day stream channels, Type B in the weathering profile and Type C occurs in relatively fresh fractured bedrock occupying open fractures and other cavities. The three types of groundwater can be distinguished both chemically and isotopically. Light stable isotope data suggest that most early rains are lost by evapotranspiration and have no imprint on the groundwater. Later in the wet season, the ground is saturated and groundwater recharge occurs on a regional scale. This younger groundwater sits on the older waters. Mixing is probably minimal as before any large scale mixing could occur, most younger waters are lost by evapotranspiration. Stable isotope data suggest that Type B groundwater in certain areas has some connection with evaporated surface water bodies. Stable isotope measurements for the pollution monitoring bores around the tailings dam do not indicate any connection with the polluted pond waters at the time of sample collection.

  14. Autonomous Navigation with Constrained Consistency for C-Ranger

    Directory of Open Access Journals (Sweden)

    Shujing Zhang

    2014-06-01

    Full Text Available Autonomous underwater vehicles (AUVs have become the most widely used tools for undertaking complex exploration tasks in marine environments. Their synthetic ability to carry out localization autonomously and build an environmental map concurrently, in other words, simultaneous localization and mapping (SLAM, are considered to be pivotal requirements for AUVs to have truly autonomous navigation. However, the consistency problem of the SLAM system has been greatly ignored during the past decades. In this paper, a consistency constrained extended Kalman filter (EKF SLAM algorithm, applying the idea of local consistency, is proposed and applied to the autonomous navigation of the C-Ranger AUV, which is developed as our experimental platform. The concept of local consistency (LC is introduced after an explicit theoretical derivation of the EKF-SLAM system. Then, we present a locally consistency-constrained EKF-SLAM design, LC-EKF, in which the landmark estimates used for linearization are fixed at the beginning of each local time period, rather than evaluated at the latest landmark estimates. Finally, our proposed LC-EKF algorithm is experimentally verified, both in simulations and sea trials. The experimental results show that the LC-EKF performs well with regard to consistency, accuracy and computational efficiency.

  15. ERA Ranger tailings corridor review. Supervising Scientist report 154

    International Nuclear Information System (INIS)

    Merz, S.K.

    2000-01-01

    Sinclair Knight Merz (SKM) were commissioned by the Office of the Supervising Scientist on 25 May 2000 to undertake a review and complete a report on the tailings corridor at the ERA Ranger Mine. The objective of the study was to undertake an 'as is' and to some extent historic and look ahead, review of the corridor system sufficient to: assess the current suitability of key aspects of the design; assess the suitability of current operating, maintenance and system development regimes and responsibilities; and record any recommended actions or further investigations arising out of the review; in order to ensure the adequacy of the design, operation and maintenance. The scope of the study report was limited to the corridor itself, its associated sump and sump contents discharge and the branch corridors carrying pipelines to Pit 1. A representative report contents was discussed and agreed with the Office of the Supervising Scientist prior to commencement of the study and this is included as appendix A to this report. The originally agreed content is, with only minor amendment, reflected in this report. The study methodology comprised a review and assessment by SKM of the design of the existing system and current operations documentation and information obtained from investigations on site and discussions with ERA site personnel. Whilst, a number of modifications affecting the corridor are recommended for further consideration, the main findings of the report relate to operating and maintenance practices which should be adopted for the remainder of the mine/mill life

  16. 77 FR 36251 - Intermountain Region, Boise National Forest; Emmett Ranger District, Idaho; Scriver Creek...

    Science.gov (United States)

    2012-06-18

    ... composition to accelerate development of large tree and old forest habitat dominated by early seral tree... noncommercial trees would occur on approximately 3,265 acres following commercial timber harvest activities; and, noncommercial thinning of small diameter trees would also occur on an additional 839 acres of existing...

  17. 75 FR 43138 - Ochoco National Forest, Lookout Mountain Ranger District; Oregon; Howard Elliot Johnson Fuels and...

    Science.gov (United States)

    2010-07-23

    ... Analysis. Generally speaking, the Watershed Analysis determined that vegetation condition in the... scoping process. The Ochoco National Forest will give notice of the full environmental analysis and.... DATES: Comments concerning the scope of the analysis must be received by August 23, 2010. The draft...

  18. 78 FR 20613 - Ochoco National Forest, Paulina Ranger District; Oregon; Wolf Creek Vegetation and Fuels...

    Science.gov (United States)

    2013-04-05

    ... 2012 and documented in the Wolf Creek Watershed Analysis. The watershed analysis determined that... includes National Forest system lands within the Lower Beavercreek watershed. The alternatives that will be... analysis and decision making process so interested and affected people may participate and contribute to...

  19. 76 FR 22670 - Black Hills National Forest, Hell Canyon Ranger District, South Dakota, Vestal Project

    Science.gov (United States)

    2011-04-22

    ... on a proposal to use multiple vegetation treatments focused on reducing the threat to ecosystem components including forest resources from an existing insect epidemic (mountain pine beetle), creating a landscape condition that reduces the potential for high severity wildfire adjacent to the at-risk community...

  20. 77 FR 59163 - Andrew Pickens Ranger District; South Carolina; AP Loblolly Pine Removal and Restoration Project

    Science.gov (United States)

    2012-09-26

    ..., dogwood, and sourwood. Stand density is high, typically ranging from 120 to 160 square feet of basal area... native forest vegetation. This change in condition would improve ecosystem [[Page 59164

  1. 78 FR 12714 - Intermountain Region, Payette National Forest, New Meadows Ranger District, Idaho; Lost Creek...

    Science.gov (United States)

    2013-02-25

    ...) reduce the risk of uncharacteristic and undesirable wildland fire; (4) restore habitat connectivity..., in Adams County Idaho. The project is designed to improve wildlife habitat, reduce forest fuels, and... and Need for Action The purpose of the project is to: (1) Improve habitat for specific wildlife...

  2. 76 FR 22360 - Superior National Forest, Gunflint, Kawishiwi, LaCroix, and Tofte Ranger Districts; Minnesota...

    Science.gov (United States)

    2011-04-21

    ... made is whether or not to implement an integrated pest management strategy to control non-native... integrity of the BWCAW, the Superior National Forest proposes to use an integrated pest management approach... accomplish these objectives, there is a need to implement an integrated pest management approach that...

  3. 78 FR 49722 - Tongass National Forest Wrangell Ranger District; Alaska; Wrangell Island Project Environmental...

    Science.gov (United States)

    2013-08-15

    ... on March 13, 2012 (77 FR 14727). This corrected NOI is being published because the project will now... not expected until after September 27, 2013, the Wrangell Island Project is now subject to these new... include 1) timber supply and timber sale economics, 2) old-growth reserve designs, and 3) road access and...

  4. 78 FR 36163 - Bitterroot National Forest, Darby Ranger District, Como Forest Health Project

    Science.gov (United States)

    2013-06-17

    ... Forest System of Roads. These road sections are needed now and in the future to access Unit 41 and units... recreation, visual quality, wildlife, fisheries, hydrology, and fire management; (3) economics of timber...

  5. 78 FR 49723 - Humboldt-Toiyabe National Forests; Ely Ranger District; Ely Westside Rangeland Project

    Science.gov (United States)

    2013-08-15

    ... Month (AUM) production for the Humboldt National Forest while improving the gap between existing and...: 1. Current Management Alternative: Continue current grazing management. 2. No Grazing Alternative... documents. (Authority: 40 CFR 1501.7 and 1508.22; Forest Service Handbook 1909.15, Section 21) Dated: August...

  6. 75 FR 64243 - Umatilla National Forest, Walla Walla Ranger District; Oregon Tollgate Fuels Reduction Project

    Science.gov (United States)

    2010-10-19

    .... This project was planned and will be implemented using Healthy Forest Restoration Act (HFRA) of 2004... actions will be conducted in accordance with the Healthy Forest Restoration Act (HFRA), National Forest... (fiber optic lines, telephone lines, power transmission lines, and communication equipment) is...

  7. 77 FR 10472 - San Bernardino National Forest, Mountaintop Ranger District, California, Mitsubishi South Quarry...

    Science.gov (United States)

    2012-02-22

    ... of the mine. The proposed South Quarry site would be able to meet the requirements for blending with... restoration practices. 3. To avoid incidental killing of birds protected under the Migratory Bird Treaty Act... proponent's ability to mine its claims on National Forest System lands. San Bernardino County will decide...

  8. 75 FR 9388 - Prescott National Forest, Bradshaw Ranger District; Arizona; Bradshaw Vegetation Management Project

    Science.gov (United States)

    2010-03-02

    ...; Arizona; Bradshaw Vegetation Management Project AGENCY: Forest Service, USDA. ACTION: Notice of intent to prepare an environmental impact statement. SUMMARY: This project is a proposal to improve the health of.... The project area encompasses about 55,554 acres. Within the project area, the proposal is to...

  9. 75 FR 71668 - Cibota National Forest, Mount Taylor Ranger District, NM, Roca Honda Mine

    Science.gov (United States)

    2010-11-24

    ... develop and conduct underground uranium mining operations on their mining claims on and near Jesus Mesa in... open to mineral entry under the General Mining Law of 1872. Section 16 is State of New Mexico land, which is not subject to the regulatory jurisdiction of the Forest Service. Roca Honda proposes a mine...

  10. 78 FR 24717 - Crescent Ranger District; Deschutes National Forest; Klamath County, Oregon; Marsh Project...

    Science.gov (United States)

    2013-04-26

    ... natural and human threats to this current range of benefits being provided, and also enhance the ecosystem... Service road 5825-540 to the public; Remove approximately 65 acres of Invasive Reed Canary Grass; Thin...

  11. 76 FR 315 - Sisters Ranger District; Deschutes National Forest; Oregon; Popper Vegetation Management Project

    Science.gov (United States)

    2011-01-04

    ...; Oregon; Popper Vegetation Management Project AGENCY: Forest Service, USDA. ACTION: Notice of intent to... submit to [email protected] . Please put ``Popper Vegetation... work to the local and regional economy; and reintroduce fire in fire dependent ecosystems in the Popper...

  12. 76 FR 4860 - Ochoco National Forest, Lookout Mountain Ranger District; Oregon; Marks Creek Allotment...

    Science.gov (United States)

    2011-01-27

    ... riparian restoration activities on some streams in the project area. These actions are needed to achieve...-mail message, or as an attachment in plain text (.txt), Microsoft Word (.doc), rich text format (.rtf), or portable document format (.pdf). FOR FURTHER INFORMATION CONTACT: Tory Kurtz, Project Leader, at...

  13. 75 FR 48927 - Sierra National Forest, Bass Lake Ranger District, California, Fish Camp Project

    Science.gov (United States)

    2010-08-12

    ... to provide a means to reduce the intensity and spread of wildland fires across the landscape and near... occurring), high hazard (availability of fuels to sustain a fire) wildland urban intermix area, (3) increase... create SPLATs to reduce the intensity and spread of wildland fire across the landscape and near...

  14. 77 FR 21721 - Sierra National Forest, Bass Lake Ranger District, California, Whisky Ecosystem Restoration Project

    Science.gov (United States)

    2012-04-11

    ... and vigor of conifer stands, reduce the spread and intensity of wildfires within and outside of the Wildland Urban Interface (WUI) and restore other ecological processes. DATES: Comments concerning the scope... on these federal and formerly private lands, combined with the exclusion of fire, have altered forest...

  15. 76 FR 65681 - Black Hills National Forest, Mystic Ranger District, South Dakota, Calumet Project Area

    Science.gov (United States)

    2011-10-24

    ... Environmental Impact Statement (EIS). SUMMARY: The Forest Service will prepare an environmental impact statement... near at-risk communities and in the wildland-urban interface. The proposal is being planned for the 31... acres of pine stands using a variety of methods to treat MPB infested stands, reduce the overall density...

  16. 76 FR 41753 - Sierra National Forest, Bass Lake Ranger District, California, Grey's Mountain Ecosystem...

    Science.gov (United States)

    2011-07-15

    ..., California, Grey's Mountain Ecosystem Restoration Project AGENCY: Forest Service, USDA. ACTION: Notice of...: Background Information: The Grey's Mountain Ecosystem Restoration Project (Madera County, California) lies... vegetation. Currently, vegetation within the Grey's Mountain Ecosystem Restoration Project has changed from...

  17. 76 FR 67130 - Bridger-Teton National Forest; Big Piney Ranger District; Wyoming; Environmental Impact Statement...

    Science.gov (United States)

    2011-10-31

    ... management actions, and (2) minimize food and other types of habituation and bear/human conflicts. Updated... project area is within the DFC 10 (Simultaneous Development of Resources, Opportunities for Human Experiences and Support for Big-game and a Wide Variety of Wildlife Species. Approximately five percent of the...

  18. 75 FR 47755 - Black Hills National Forest, Mystic Ranger District, South Dakota, Pactola Project Area

    Science.gov (United States)

    2010-08-09

    ... fuels, and to increase the quantity and quality of forage for big game and other wildlife resources... the subject. Electronic comments must be readable in Word, Rich Text or PDF formats. FOR FURTHER...,755 acres); MA 5.3A; MA 5.4--Big Game Winter Range Emphasis (~12,201 acres); and MA 8.2 Developed...

  19. 76 FR 54730 - Rubicon Trail Easement, Eldorado National Forest, Pacific Ranger District

    Science.gov (United States)

    2011-09-02

    ... waters of the state, and address human waste management on the Rubicon Trail. Proposed Action The... through these low spots thereby accelerating trail erosion and sedimentation. In July 2004, the El Dorado... fecal waste littered around the Spider Lake area. The amount of fecal waste was determined to pose a...

  20. 75 FR 68319 - Paulina Ranger District; Ochoco National Forest; Crook and Wheeler Counties, OR; Jackson...

    Science.gov (United States)

    2010-11-05

    ... 1,500 acres. Providing wood products will include removing some standing dead wood (snags) as...; the forest stands in the project area have the potential to provide wood products. This project is... grass communities and provide wood products for public needs and for the health of local and regional...

  1. 76 FR 31932 - Beaverhead-Deerlodge National Forest, Pintler Ranger District; Montana; Flint Foothills...

    Science.gov (United States)

    2011-06-02

    ... to (1) salvage harvest dead and dying lodgepole pine stands to create managed conditions and harvest wood products from forested stands infested or at risk for infestation with bark beetles before the value of the wood deteriorate; (2) reduce forest densities in low elevation ponderosa pine and Douglas...

  2. 77 FR 19177 - Beaverhead-Deerlodge National Forest, Jefferson Ranger District, Montana, Boulder River Salvage...

    Science.gov (United States)

    2012-03-30

    ... statement. SUMMARY: The project proposes to salvage by clearcut harvest dead and lodgepole pine infested or... Need for Action The purpose and need for this project is to harvest merchantable wood products from..., before the value of the wood deteriorates; reduce stand density in lodgepole pine and Douglas-fir stands...

  3. 77 FR 66578 - San Bernardino National Forest, Mountaintop Ranger District, CA, Santa Ana Watershed Hazardous...

    Science.gov (United States)

    2012-11-06

    ... shrub and herbaceous fuels and down wood in these areas. In some of these areas, dead trees would be cut... treatment and would result in an open forest structure with no standing dead trees, down logs, or other..., direct removal, or through hand or machine piling and burning. Wood slash piles would be burned, once the...

  4. 76 FR 35396 - Black Hills National Forest, Mystic Ranger District, South Dakota, Section 30 Limestone Mining...

    Science.gov (United States)

    2011-06-17

    ... 60 acres will be disturbed at any one time. Reclamation will result in a depression on the existing... statutory exemption for the extraction of cement precursors. Pennington County Construction (Mining) Permit...

  5. 75 FR 25198 - Intermountain Region, Boise National Forest, Emmett Ranger District; Idaho Scriver Creek...

    Science.gov (United States)

    2010-05-07

    ... structure, density, and species composition in order to accelerate development of larger tree size class... acres), and helicopter (1,215 acres) logging systems. In addition, all acres treated by commercial timber activities (about 3,265 acres) would be followed by thinning of submerchantable trees. About 839...

  6. 75 FR 10457 - Andrew Pickens Ranger District; South Carolina; AP Loblolly Pine Removal and Restoration Project

    Science.gov (United States)

    2010-03-08

    ... relatively low tree densities of 25-60% forest cover with understories that are dominated by native grasses... trees exist in the overstory of most of these stands and hardwood sprouts and saplings abound in the... in pine plantations. Other stands are sparse due to poor planting success or to past logging that did...

  7. 77 FR 17007 - Kootenai National Forest, Cabinet Ranger District, Montana Pilgrim Timber Sale Project

    Science.gov (United States)

    2012-03-23

    ...-resistant tree species in the area; there is a need to increase age class diversity in lodgepole pine... proposed, most of which would be removed with cable logging systems. Approximately 55- 75 acres would be... trees. To access proposed harvest areas, approximately 3.1 miles of new, permanent road would need to be...

  8. RELATIONSHIPS IN THE WORKPLACE AND OCCUPATIONAL ATTRACTIVENESS AMONG STUDENTS, TEACHERS AND RANGERS-SPORTSMEN

    Directory of Open Access Journals (Sweden)

    Nikolay Ivantchev

    2016-06-01

    Full Text Available Perceived occupational attractiveness could be due to many factors and relationships in the workplace are among them. The questionnaire “Attractiveness of the profession” created by Ivanov (1999 was used to study how relationships in the workplace were related to perceptions of occupational attractiveness among students, teachers and rangers-sportsmen participating in special missions abroad. In 2012 and 2013, 46 secondary school teachers, 40 students in pedagogical specialties, and 27 sportsmen-rangers participating in special missions abroad were studied in Bulgaria. The results indicated that the students and the rangers were more satisfied with their work than the teachers were. The interpersonal relationships influenced mainly the students’ and rangers’ perceptions of occupational attractiveness. The rangers were more influenced by the relationships with the colleagues. The psycho-climate in the workplace was considered as more important by the rangers. The students were more influenced by the interpersonal communication at the workplace and their heads’ expertise. Some moderators of interpersonal relationships in the workplace were found – such as the tasks in the work, the prestige of occupation, the interaction between occupation and rewards, and the psycho-climate in the workplace.

  9. Age of uranium ores at Ranger and Jabiluka unconformity vein deposits, Northern Territory, Australia

    International Nuclear Information System (INIS)

    Ludwig, K.R.; Grauch, R.I.; Nutt, C.J.; Frishman, D.; Nash, J.T.; Simmons, K.R.

    1985-01-01

    The Ranger and Jabiluka uranium deposits are the largest in the Alligator Rivers Uranium Field (ARUF), which contains at least 20% of the world's low-cost uranium reserves. Ore occurs in early Proterozoic metasediments, below an unconformity with sandstones of the 1.65 Ga Kombolgie Formation. This study uses U-Pb isotope data from over 60 whole-rock drill core samples that contained a variety of mineral assemblages and textures. Data for Ranger samples indicate a well-defined age of 1.74 +/-.02 Ga. This 1.74 Ga age is distinctly pre-Kombolgie, so the Ranger deposit cannot have been formed by processes requiring its presence. This Ranger age is consistent, however, with mineralization related to heating associated with either the emplacement of early post-metamorphic granites, or possibly with intrusion of the nearby Oenpelli Dolerite. In contrast, data for the least-altered Jabiluka ores yield a concordia-intercept age of 1.44 +/-.02 Ga--significantly younger than the Ranger age, and also younger than the Komobolgie. This age may correspond to a regional thermal event, as indicated both by mafic dikes of roughly this age and a zircon lower-intercept age from a nearby granite-gneiss. Thus, together with the well-defined ∼900 Ma age of ores at the Nabarlek deposit, there are at least 3 distinct periods of major U-mineralization in the ARUF. Data for both Ranger and Jabiluka indicate the same, profound isotopic disturbance at some time in the interval of 0.4-0.6 Ga. Possibly this time corresponds to the development of basins and associated basalt flows to the W and SW, a suggested by Crick et. al. (1980)

  10. Unruly Woman: An Interview with Helen Lewis.

    Science.gov (United States)

    Briscoe, Lori; Collins, Erica S.; Deal, Amanda; Hancock, Ron; McGraw, Kristyn; Lewis, Helen

    2000-01-01

    Overviews the career of Helen Lewis as sociologist, social activist, teacher, writer, researcher, and mentor. Helen Lewis discusses growing up in segregated Georgia, her unorthodox approach to education, her fight for social and economic equality, her instrumental role in the development of Appalachian Studies programs, and how social activism…

  11. Frustrated Lewis pairs: Design and reactivity

    Indian Academy of Sciences (India)

    for FLP systems and their unique reactivity are discussed here. Keywords. Lewis .... we will concentrate on the design principles of such. FLPs and the ... Designs of frustrated Lewis pairs ..... 64 and neutral titanium (III) complex [Cp2TiOC6.

  12. Council Districts

    Data.gov (United States)

    Town of Cary, North Carolina — View the location of the Town of Cary’s four Town Council districts.Please note that one district, District A, is split into two geo-spatial areas. One area is in...

  13. Quantification of Lewis acid induced Brønsted acidity of protogenic Lewis bases.

    Science.gov (United States)

    Lathem, A Paige; Heiden, Zachariah M

    2017-05-09

    Proton transfer promoted by the coordination of protogenic Lewis bases to a Lewis acid is a critical step in catalytic transformations. Although the acidification of water upon coordination to a Lewis acid has been known for decades, no attempts have been made to correlate the Brønsted acidity of the coordinated water molecule with Lewis acid strength. To probe this effect, the pK a 's (estimated error of 1.3 pK a units) in acetonitrile of ten protogenic Lewis bases coordinated to seven Lewis acids containing Lewis acidities varying 70 kcal mol -1 , were computed. To quantify Lewis acid strength, the ability to transfer a hydride (hydride donor ability) from the respective main group hydride was used. Coordination of a Lewis acid to water increased the acidity of the bound water molecule between 20 and 50 pK a units. A linear correlation exhibiting a 2.6 pK a unit change of the Lewis acid-water adduct per ten kcal mol -1 change in hydride donor ability of the respective main group hydride was obtained. For the ten protogenic Lewis bases studied, the coordinated protogenic Lewis bases were acidified between 10 and 50 pK a units. On average, a ten kcal mol -1 change in hydride donor ability of the respective main group hydride resulted in about a 2.8 pK a unit change in the Brønsted acidity of the Lewis acid-Lewis base adducts. Since attempts to computationally investigate the pK a of main group dihydrogen complexes were unsuccessful, experimental determination of the first reported pK a of a main group dihydrogen complex is described. The pK a of H 2 -B(C 6 F 5 ) 3 was determined to be 5.8 ± 0.2 in acetonitrile.

  14. Constancy and cover of plants in the Petersburg and Wrangell Districts, Tongass National Forest and associated private and other public lands, southeast Alaska.

    Science.gov (United States)

    Bert R. Mead

    2002-01-01

    This study provides a comprehensive and inclusive description and inventory of the vegetation within the Stikine area of southeast Alaska. Private and other public lands were included as well as Tongass National Forest lands contained in the Petersburg and Wrangell Ranger Districts. Previous inventories have concentrated almost exclusively on tree species within forest...

  15. Conservation′s Ambiguities: Rangers on the Periphery of the W Park, Burkina Faso

    Directory of Open Access Journals (Sweden)

    Julie Poppe

    2012-01-01

    Full Text Available This article demonstrates the central role of ambiguity in the (reproduction process of conservation practice. It argues that some current political economy as well as environmentality approaches to research conservation practice fail to capture the complexity of the lived experience of local conservationists. The article focuses on the multiple identities of rangers in interaction with other residents at the periphery of the W Park in Burkina Faso, as rangers are local conservationists who simultaneously submit to and produce conservation practices. Park rangers are village men who are recruited under the banner of community participation in conservation projects and state forestry. On a day-to-day basis, these rangers help the foresters with the management of the natural resources on the one hand, and guide tourists, especially in the hunting concessions, on the other. They occupy ambiguous positions at the crossroads of conservationist, state, political, economic, spiritual, social, and cultural practices, inherent to their conservation occupations at the lowest echelon, where residents have to transform conservation policies into practices. It is precisely this ambiguity that turns out to ensure the conservation implementation.

  16. The radiological impact of the Ranger Uranium Mine on the general public in Jabiru

    International Nuclear Information System (INIS)

    Kavasnicka, Jiri

    1992-01-01

    Potential alpha energy concentrations (PAEC) of radon daughters were monitored by a Kodak LR 115 nuclear track detector both outdoors and indoors in Jabiru (a township 9 km west of the Ranger Uranium Mine) at five locations between Ranger and Jabiru during the 1989 Dry Season. The average outdoor PAEC and the indoor PAEC in private dwellings in Jabiru were 2.4 ± 0.2 mWL and 2.4 ± 0.7 mWL respectively. Though the total radon emission from the Ranger Uranium Mine (RUM) project is relatively high (about 7 MBq s -1 ) the mining and milling of uranium contributes only marginally to the PAEC in Jabiru as can be seen from results of the air dispersion modelling and environmental radon daughter monitoring carried out in parallel with the indoor monitoring in Jabiru. The description of the radon daughter monitor and the major characteristics of the RUM project are given in the Appendixes. The average annual PAEC in Jabiru attributable t the mining and milling operations at Ranger was calculated to be about 0.16 mWL, which corresponds to an effective dose equivalent of 0.07 mSv y -1 (7% of the 1 mSv y -1 public limit) for members of the public in Jabiru. 17 refs., 3 tab., 7 figs

  17. Land application at Ranger uranium mine, northern Australia: six years'review

    International Nuclear Information System (INIS)

    Noller, B.N.; Zhou, J.X.

    1992-01-01

    This report reviews the six years' practice of land application of waste water at the Ranger Uranium Mine, northern Australia. Elements of significance to the chemical impact on the environment by mining and milling at Ranger are analysed taking into consideration ore petrology and mineralogy, chemical compositions of rocks and ore, relative enrichment of different rock- and ore-forming elements, and the chemicals involved in the milling and extraction processes. Biogeochemistry of land application of waste water as an efficient environmental managing technique is discussed by analysing its biogeochemical cycles, variables which affect the biogeochemical processes, and aqueous chemistry. Data from monitoring of the soils, groundwater, biota, and seepage in the land application area at Ranger are collected and re-organised. A new approach to data presentation and interpretation is made based on the analysis of the most important variables which may affect the extent of the chemical impact of land application of waste water. The environmental impact of land application of waste water on soils, ground water, biota, and surface water (through seepage) is assessed accordingly. Uranium is retained in the near-surface soil layer while sulfate is present at lower depths. Manganese shows some mobility, appearing in depressions. Radium 226 shows no clear-cut relationship between location of soil sample and level. It is concluded that land application of waste water at Ranger has resulted in minimal environmental impact. 4 refs

  18. Management of Ranger uranium mine waters, Kakadu Region, Northern Territory, Australia

    International Nuclear Information System (INIS)

    Hallenstein, C.; Bastias, J.

    1988-01-01

    The objectives, development and operation of the Ranger Uranium Mine's water management system are discussed. The discharge standards for release of excess mine water to Magela Creek are described and mine water quality data presented. It can be confidently concluded that controlled release will not cause detriment to the aquatic ecosystems of the Kakadu region. 4 refs., 1 fig., 3 tabs

  19. The contribution of the Ranger Uranium Mine to the Northern Territory and Australian economy

    International Nuclear Information System (INIS)

    1993-09-01

    This is the report of a study by ACIL Economics and Policy Pty Ltd (ACIL) which estimates the contribution of the fist eleven years of the Ranger uranium project to the Northern Territory and Australian economies. It looks at the purchases and sales by the Company and the contributions of the project to tourism, the town of Jabiru, scientific work and royalty and taxation revenues. In the process it also assembles the available data on monies that have flowed from Ranger operations to the Aboriginal people of the Northern Territory. The analyses in intended to enable Ranger's contribution to be compared with that of other activities in the economy. Thus care has been taken to employ accepted national accounting definitions and to apply a degree of rigor which ensures that the figures generated are meaningful in relation to the official statistics covering the economy which are produced by the Australian Bureau of Statistics. Besides analysing the net economic contribution of Ranger, the report looks at certain distributional aspects, in particular the impact on Aboriginal people. The vast majority of Ranger's value-added contribution has been in a form that appears in ERA's accounts. Side-benefits estimated to have been generated through supplying infrastructure used by Kakadu tourist, excess-payments for town-building and its contribution through the existence of the Office of the Supervising Scientist have been significant in absolute terms, but over the mine's life so far these side-benefits have not added more than five per cent to the mine's GDP contribution. 20 tabs., 3 figs

  20. Nitrile ylides: diastereoselective cycloadditions using chiral oxazolidinones without Lewis acid.

    Science.gov (United States)

    Sibi, Mukund P; Soeta, Takahiro; Jasperse, Craig P

    2009-12-03

    Lewis acid complexation is generally required for chiral-auxiliary-controlled stereoselectivity, and chiral Lewis acid catalysis is frequently optimal for introducing asymmetry. In this work, we show that nitrile ylide cycloadditions to electron-poor acceptors attached to chiral auxiliaries proceed in high yield and stereoselectivity in the absence of Lewis acids. In contrast, chiral Lewis acids are inferior in these cycloadditions.

  1. SSTI- Lewis Spacecraft Nickel-Hydrogen Battery

    Science.gov (United States)

    Tobias, R. F.

    1997-01-01

    Topics considered include: NASA-Small Spacecraft Technology Initiative (SSTI) objectives, SSTI-Lewis overview, battery requirement, two cells Common Pressure Vessel (CPV) design summary, CPV electric performance, battery design summary, battery functional description, battery performance.

  2. Edward B Lewis (1918–2004)

    Indian Academy of Sciences (India)

    Administrator

    Ed Lewis spent his life working on the genetics of Dro- sophila with ... bithorax mutations, in which organs that control balance ... His pioneering work on homeotic genes induced ... a close and cooperative family within the larger scientific.

  3. RANGER-DTL 2.0: Rigorous Reconstruction of Gene-Family Evolution by Duplication, Transfer, and Loss.

    Science.gov (United States)

    Bansal, Mukul S; Kellis, Manolis; Kordi, Misagh; Kundu, Soumya

    2018-04-24

    RANGER-DTL 2.0 is a software program for inferring gene family evolution using Duplication-Transfer-Loss reconciliation. This new software is highly scalable and easy to use, and offers many new features not currently available in any other reconciliation program. RANGER-DTL 2.0 has a particular focus on reconciliation accuracy and can account for many sources of reconciliation uncertainty including uncertain gene tree rooting, gene tree topological uncertainty, multiple optimal reconciliations, and alternative event cost assignments. RANGER-DTL 2.0 is open-source and written in C ++ and Python. Pre-compiled executables, source code (open-source under GNU GPL), and a detailed manual are freely available from http://compbio.engr.uconn.edu/software/RANGER-DTL/. mukul.bansal@uconn.edu.

  4. Slovene critics on Sinclair Lewis's novels

    Directory of Open Access Journals (Sweden)

    Vanja Avsenak

    2010-12-01

    Full Text Available The purpose of this article is to present the reception of Sinclair Lewis's novels by Slovene critics. Initially, the article focuses on the life and workof Sinclair Lewis, giving special emphasis to social influences that made the author a representative figure in the literary and social world. Thus his works are nowadays to be understood primarily as fiction, but on the other hand also as sociological documents of a social and political situation of the period between the two world wars. Generally, the effect they produce is one of a critical discussion of the nation of the United States. When speaking of the social relevance that Lewis's novels have, it is obvious that his works are the portrayals of Americans and their deficiencies. At the time of their publication Lewis's novels received unfavourable criticism on accountof his overly open pro-European attitude and Slovene critics of the period before World War II emphasise this in much detail. It was precisely this anti-American propaganda in the novels themselves and sincerity on the part of the novelist that won the European critics as well as the readers whenit came to appreciating his works. However, Lewis's view of the Americans, as presented throughout his works, only enhanced his literary credibility as a modern writer. That is why the articles by Slovene critics that appeared after the Second World War, and even more significantly after Lewis's death, almost minutely reflect a more favourable attitude to Sinclair Lewis, which was also the case with foreign literary criticism of the post-war period. Critics still discuss the qualities and flaws of Lewis's novels, but being more lenient they no longer profess that the novels lack in artistic value. They remain, however, primarily relevant as social documents of the pre- and post-war era, which fully presented the American middle-class mentality in America and elsewhere. For this reason, the Nobel Prize for Literature awarded to

  5. Environmental impact of the Ranger uranium mine, Alligator Rivers Region, Northern Territory, Australia

    International Nuclear Information System (INIS)

    Johnston, A.; Needham, S.

    2002-01-01

    Stringent environmental controls have been applied to the Ranger mine, in the Northern Territory of Australia, because of its location in an area of outstanding natural and cultural values. The adjacent Kakadu National Park contains a wild and extensive biodiversity, striking landscapes, ancient Aboriginal rock art and a living Aboriginal culture. A special regime of biological, radiological and chemical monitoring has been applied to protect the environment and detect even very low intensity impacts. The results from this regime demonstrate to the government and general public that the high conservation values of the national park around the mine are being properly protected. This paper describes the techniques used to measure environmental impact at Ranger, and summarizes the results of over 20 years of monitoring. The overwhelming conclusion is that a very high standard of environmental protection has been achieved. (author)

  6. Contingency planning and risk analysis for water and tailings management at Ranger Uranium Mines

    International Nuclear Information System (INIS)

    McNally, P.E.

    1986-01-01

    This paper describes some of the more likely risks and contingency procedures associated with the extremely variable monsoonal climate of the Alligator Rivers region in the Northern Territory in relation to the Ranger Uranium Mine. The tailings management system is basically a large storage impoundment and a reticulation system that delivers tailings sludge and recycles supernatant water. It is a closed circuit within the water management system and is dealt with as an integral part of that system

  7. Expansion of the ore treatment plant at Ranger Uranium Mines at Jabiru, NT Australia

    International Nuclear Information System (INIS)

    Nice, R.W.; Banaczkowski, M.

    2000-01-01

    The Ranger Uranium Mine commenced processing ore in 1980. The original plant designed by the joint venture between Davy and Wright Engineers had been designed to treat 1.3 Mtpa of ore to produce 3500 tpa of U 3 O 8 concentrates. The plant operated successfully through good and bad years until the 1995 when the owners of Energy Resources of Australia, North Ltd. (70%) decided that there was a market opening to allow expansion of the treatment plant such that it would produce 6000 tpa of concentrate.The desire to produce more concentrates was market driven but the change from the mine Ranger 1 to a new pit Ranger 3 also necessitated the inclusion of the ability to treat more ore. This involved the installation of more grinding and CCD washing capacity. There were some other changes that were to be included into the expansion to overcome operating deficiencies, reduce operating costs and to generally make the operation easier.The Australian engineering company, Kvaerner Davy, was commissioned to provide the EPCM services to the clients, North and the Ranger Operation Group. North Technical Services managed the Project with considerable input from the site operating and maintenance personnel. The site operating personnel commissioned the plant and are successfully operating it at the time of the preparation of this paper. The first part of this paper presents the basic process related activities required to provide the expanded facilities. This includes the flowsheet modifications, equipment changes and new equipment procured. Additionally, a discussion is given regarding the P and ID changes, the piping modifications and the means to install the expanded facilities with a minimum of interruption to the continuing plant operation. A second part of the paper details some of the experiences gained while constructing the expansion and commissioning and operating the expanded plant. (author)

  8. High Precision Ranging and Range-Rate Measurements over Free-Space-Laser Communication Link

    Science.gov (United States)

    Yang, Guangning; Lu, Wei; Krainak, Michael; Sun, Xiaoli

    2016-01-01

    We present a high-precision ranging and range-rate measurement system via an optical-ranging or combined ranging-communication link. A complete bench-top optical communication system was built. It included a ground terminal and a space terminal. Ranging and range rate tests were conducted in two configurations. In the communication configuration with 622 data rate, we achieved a two-way range-rate error of 2 microns/s, or a modified Allan deviation of 9 x 10 (exp -15) with 10 second averaging time. Ranging and range-rate as a function of Bit Error Rate of the communication link is reported. They are not sensitive to the link error rate. In the single-frequency amplitude modulation mode, we report a two-way range rate error of 0.8 microns/s, or a modified Allan deviation of 2.6 x 10 (exp -15) with 10 second averaging time. We identified the major noise sources in the current system as the transmitter modulation injected noise and receiver electronics generated noise. A new improved system will be constructed to further improve the system performance for both operating modes.

  9. An assessment of the water management program proposed in the Ranger EIS and its environmental implications

    International Nuclear Information System (INIS)

    Davy, D.R.

    1976-01-01

    An assessment of the water management program proposed in the Ranger EIS has three components: a) a statement of water quality criteria and standards that the program must meet, b) a set of calculations based on the best available estimates, that compares the expected levels of waste with the standards set for the release, c) the plan of the surveillance program aimed at demonstrating compliance with these standards and at revealing deficiencies in the choice of criteria, the derivation of standards from them and unforseen departures from expectation. Standards are suggested for the operation of the Ranger mines based on the most restrictive criterion out of: (i) acute toxicity tests carried out on organisms and water from the Magela Creek combined with application factors recommended by AWRC, (ii) the results on indicator species and biological diversity indices for the Finniss river, (iii) requirements for agricultural and pastoral use, (iv) the requirements for portable water. It is expected that the program proposed by Ranger will meet these standards and it is concluded that planning for a comprehensive environmental program is adequate. (author)

  10. Complexation of Nitrous Oxide by Frustrated Lewis Pairs

    NARCIS (Netherlands)

    Otten, Edwin; Neu, Rebecca C.; Stephan, Douglas W.

    2009-01-01

    Frustrated Lewis pairs comprised of a basic yet sterically encumbered phosphine with boron Lewis acids bind nitrous oxide to give intact PNNOB linkages. The synthesis, structure, and bonding of these species are described.

  11. RangerMaster trademark: Real-time pattern recognition software for in-field analysis of radiation sources

    International Nuclear Information System (INIS)

    Murray, W.S.; Ziemba, F.; Szluk, N.

    1998-01-01

    RangerMaster trademark is the embedded firmware for Quantrad Sensor's integrated nuclear instrument package, the Ranger trademark. The Ranger trademark, which is both a gamma-ray and neutron detection system, was originally developed at Los Alamos National Laboratory for in situ surveys at the Plutonium Facility to confirm the presence of nuclear materials. The new RangerMaster trademark software expands the library of isotopes and simplifies the operation of the instrument by providing an easy mode suitable for untrained operators. The expanded library of the Ranger trademark now includes medical isotopes 99 Tc, 201 Tl, 111 In, 67 Ga, 133 Xe, 103 Pa, and 131 I; industrial isotopes 241 Am, 57 Co, 133 Ba, 137 Cs, 40 K, 60 Co, 232 Th, 226 Ra, and 207 Bi; and nuclear materials 235 U, 238 U, 233 U, and 239 Pu. To accomplish isotopic identification, a simulated spectrum for each of the isotopes was generated using SYNTH. The SYNTH spectra formed the basis for the knowledge-based expert system and selection of the regions of interest that are used in the pattern recognition system. The knowledge-based pattern recognition system was tested against actual spectra under field conditions

  12. RangerMasterTM: real-time pattern recognition software for in-field analysis of radiation sources

    International Nuclear Information System (INIS)

    Murray, W.S.; Ziemba, F.; Szluk, N.

    1998-01-01

    RangerMaster TM is the embedded firmware for Quantrad Sensor's integrated nuclear instrument package, the Ranger TM . The Ranger TM , which is both a gamma-ray and neutron detection system, was originally developed at Los Alamos National Laboratory for in situ surveys at the Plutonium Facility to confirm the presence of nuclear materials. The new RangerMaster TM software expands the library of isotopes and simplifies the operation of the instrument by providing an 'easy' mode suitable for untrained operators. The expanded library of the Ranger TM now includes medical isotopes 99 Tc, 201 Tl, 111 In, 67 Ga, 133 Xe, 103 Pa, and 131 I; industrial isotopes 241 Am, 57 Co, 133 Ba, 137 Cs, 40 K, 60 Co, 232 Th, 226 Ra, and 207 Bi; and nuclear materials 235 U, 238 U, 233 U, and 239 Pu. To accomplish isotopic identification, a simulated spectrum for each of the isotopes was generated using SYNTH 2 . The SYNTH spectra formed the basis for the knowledge-based expert system and selection of the regions of interest that are used in the pattern recognition system. The knowledge-based pattern recognition system was tested against actual spectra under field conditions. (author)

  13. One hundred years of Lewis Chemical Bond!

    Indian Academy of Sciences (India)

    2016-09-20

    Sep 20, 2016 ... was a conceptual quantum jump, coming more than a decade ahead of ... did use a 'cubic model of atoms' with eight electrons in their corners, he realized that ... started referring to these advances as Lewis-Langmuir theory.

  14. Playing around in Lewis Carroll's "Alice" Books

    Science.gov (United States)

    Susina, Jan

    2010-01-01

    Mathematician Charles Dodgson's love of play and his need for rules came together in his use of popular games as part of the structure of the two famous children's books, "Alice in Wonderland" and "Through the Looking-Glass," he wrote under the pseudonym Lewis Carroll. The author of this article looks at the interplay between…

  15. The Critical Reception of Lewis Nordan

    DEFF Research Database (Denmark)

    Bjerre, Thomas Ærvold

    2010-01-01

    The essay covers the critical reception of Mississippi-writer Lewis Nordan from his debut in 1983 to the boost in scholarly attention in the new millennium. The essay covers newspaper reviews but pays particular attention to the many academic essays that have placed Nordan as a writer...

  16. Lewis acid controlled regioselectivity in styrene hydrocyanation

    NARCIS (Netherlands)

    Bini, L.; Pidko, E.A.; Müller, C.; Santen, van R.A.; Vogt, D.

    2009-01-01

    According to present knowledge, the Ni-catalyzed hydrocyanation of styrene leads predominantly to the branched product 2-phenylpropionitrile (98%). We observed a dramatic inversion of the regioselectivity upon addition of a Lewis acid. Up to 83 % of the linear product 3-phenylpropionitrile was

  17. Frustrated Lewis pairs-assisted tritium labeling

    Czech Academy of Sciences Publication Activity Database

    Marek, Aleš; Široká, Sabina; Elbert, Tomáš

    2016-01-01

    Roč. 14, č. 5 (2016), s. 219 ISSN 2336-7202. [Sjezd českých a slovenských chemických společností /68./. 04.09.2016-07.09.2016, Praha] Institutional support: RVO:61388963 Keywords : frustrated Lewis pairs * one-pot synthesis * tritium -labeling Subject RIV: CC - Organic Chemistry

  18. Teaching Beginning Chemistry Students Simple Lewis Dot Structures

    Science.gov (United States)

    Nassiff, Peter; Czerwinski, Wendy A.

    2015-01-01

    Students beginning their initial study of chemistry often have a difficult time mastering simple Lewis dot structures. Textbooks show students how to manipulate Lewis structures by moving valence electron dots around the chemical structure so each atom has an octet or duet. However, an easier method of teaching Lewis structures for simple…

  19. Managing the Ranger uranium mine in the Alligator Rivers Region -there is much more to this business enterprise than just production

    International Nuclear Information System (INIS)

    Leggate, J.

    1984-01-01

    Environmental protection is very closely and continuously regulated at the Ranger uranium mine. Since the commencement of operations at Ranger the company has operated within these regulations and demonstrated clearly that yellowcake can be produced efficiently, economically and safely. The company also recognises that in order to ensure continuity of production, it will have to continue to operate within these strictly supervised regulations

  20. Chemical data and statistical interpretations for rocks and ores from the Ranger uranium mine, Northern Territory, Australia

    Science.gov (United States)

    Nash, J. Thomas; Frishman, David

    1983-01-01

    Analytical results for 61 elements in 370 samples from the Ranger Mine area are reported. Most of the rocks come from drill core in the Ranger No. 1 and Ranger No. 3 deposits, but 20 samples are from unmineralized drill core more than 1 km from ore. Statistical tests show that the elements Mg, Fe, F, Be, Co, Li, Ni, Pb, Sc, Th, Ti, V, CI, As, Br, Au, Ce, Dy, La Sc, Eu, Tb, Yb, and Tb have positive association with uranium, and Si, Ca, Na, K, Sr, Ba, Ce, and Cs have negative association. For most lithologic subsets Mg, Fe, Li, Cr, Ni, Pb, V, Y, Sm, Sc, Eu, and Yb are significantly enriched in ore-bearing rocks, whereas Ca, Na, K, Sr, Ba, Mn, Ce, and Cs are significantly depleted. These results are consistent with petrographic observations on altered rocks. Lithogeochemistry can aid exploration, but for these rocks requires methods that are expensive and not amenable to routine use.

  1. Spatiotemporal trends of illegal activities from ranger-collected data in a Ugandan national park.

    Science.gov (United States)

    Critchlow, R; Plumptre, A J; Driciru, M; Rwetsiba, A; Stokes, E J; Tumwesigye, C; Wanyama, F; Beale, C M

    2015-10-01

    Within protected areas, biodiversity loss is often a consequence of illegal resource use. Understanding the patterns and extent of illegal activities is therefore essential for effective law enforcement and prevention of biodiversity declines. We used extensive data, commonly collected by ranger patrols in many protected areas, and Bayesian hierarchical models to identify drivers, trends, and distribution of multiple illegal activities within the Queen Elizabeth Conservation Area (QECA), Uganda. Encroachment (e.g., by pastoralists with cattle) and poaching of noncommercial animals (e.g., snaring bushmeat) were the most prevalent illegal activities within the QECA. Illegal activities occurred in different areas of the QECA. Poaching of noncommercial animals was most widely distributed within the national park. Overall, ecological covariates, although significant, were not useful predictors for occurrence of illegal activities. Instead, the location of illegal activities in previous years was more important. There were significant increases in encroachment and noncommercial plant harvesting (nontimber products) during the study period (1999-2012). We also found significant spatiotemporal variation in the occurrence of all activities. Our results show the need to explicitly model ranger patrol effort to reduce biases from existing uncorrected or capture per unit effort analyses. Prioritization of ranger patrol strategies is needed to target illegal activities; these strategies are determined by protected area managers, and therefore changes at a site-level can be implemented quickly. These strategies should also be informed by the location of past occurrences of illegal activity: the most useful predictor of future events. However, because spatial and temporal changes in illegal activities occurred, regular patrols throughout the protected area, even in areas of low occurrence, are also required. © 2015 Society for Conservation Biology.

  2. Robust Pose Estimation using the SwissRanger SR-3000 Camera

    DEFF Research Database (Denmark)

    Gudmundsson, Sigurjon Arni; Larsen, Rasmus; Ersbøll, Bjarne Kjær

    2007-01-01

    In this paper a robust method is presented to classify and estimate an objects pose from a real time range image and a low dimensional model. The model is made from a range image training set which is reduced dimensionally by a nonlinear manifold learning method named Local Linear Embedding (LLE)......). New range images are then projected to this model giving the low dimensional coordinates of the object pose in an efficient manner. The range images are acquired by a state of the art SwissRanger SR-3000 camera making the projection process work in real-time....

  3. A Biography of Distinguished Scientist Gilbert Newton Lewis (by Edward S. Lewis)

    Science.gov (United States)

    Harris, Reviewed By Harold H.

    1999-11-01

    The Edward Mellen Press: Lewiston, NY, 1998. 114 pp + index. ISBN 0-7734-8284-9. $69.95. There may not be a surname better known to students of chemistry than Lewis, from the Lewis electron-dot diagrams and the Lewis theory of acids and bases. More advanced students may know of the groundbreaking textbook Thermodynamics, by Lewis and Randall. Yet few Americans know much about this remarkable U.S.-born scholar, whose contributions equal those of the greatest scientists. He is a chemist-educator of whom we should be as proud and as well informed as we are of Linus Pauling, who was part of the westward movement of science in this country that G. N. Lewis began, or of the recently deceased Glenn Seaborg, who was one of the many students of Lewis who achieved renown. Gilbert N. Lewis was born in Weymouth, Massachusetts, in 1875, but his family moved to near Lincoln, Nebraska, in 1884. He spent two years at the University of Nebraska, but then moved to Harvard when his father became an executive at Merchants Trust Company in Boston. Young Lewis (then only 17) was also said to have been disappointed with the quality of education in Nebraska, and this may have been part of the impetus for the family's move east. After earning his baccalaureate at Harvard, he taught for a year at Phillips Andover Academy before returning to Harvard to study for his doctorate, which he completed 100 years ago, in 1899, under T. W. Richards. Lewis's doctoral work was on the thermodynamics of zinc and cadmium amalgams. At that time, physical chemistry was only beginning to achieve recognition as a branch of science, and its boundaries were ill defined. Edward Lewis quotes his father as often saying, "Physical chemistry is anything interesting." Like many chemists of his time, Lewis went to Europe to complete his preparation for a career; he was in the laboratories of Ostwald in Leipzig and Nernst in Göttingen in 1900-1901. On his return to the United States, he was an instructor at Harvard

  4. C. S. Lewis: The Romantic Rationalist

    Directory of Open Access Journals (Sweden)

    Vasiliu Daniela

    2014-12-01

    Full Text Available The paper “C. S. Lewis: The Romantic Rationalist” presents the way C. S. Lewis gives an account in his first fictional (allegorical book, The Pilgrim’s Regress, of how he discovered Christianity on the converging paths of romanticism and rationalism. The outstanding scholar and author whose intellectual and spiritual development has turned him into one of the most influential Christian writers of the twentieth century became an atheist in his teens and after a long journey through different philosophical convictions he converted to Christianity in his early thirties, a change that affected his entire work. His love of literature was essential in discovering both the rational and the imaginative appeal of Christianity, which led him into a vision of the reality of the world and of life that satisfied the longing of his heart and the hunger of his imagination.

  5. Capgras' syndrome in dementia with Lewy bodies.

    Science.gov (United States)

    Marantz, Andrew G; Verghese, Joe

    2002-01-01

    We report the occurrence of Capgras' syndrome, or the delusion of doubles, in a patient with dementia with Lewy bodies. The patient believed that several similar-looking impostors had replaced his wife of over 50 years. Uncharacteristically, he adopted a friendly attitude with these impostors. This unusual convivial reaction to the impostors may result from differential involvement of the dual visual pathways processing facial recognition and emotional responses to faces. The delusion resolved spontaneously, coincident with worsening of the dementia. In a retrospective chart review of 18 autopsy-confirmed cases of dementia with Lewy bodies, delusions were reported in 5 subjects (27.8%), of whom 1 had misidentification delusions much like Capgras' syndrome.

  6. Rendezvous, un juego de Lewis Carroll

    Directory of Open Access Journals (Sweden)

    José Manuel Sánchez Muñoz

    2011-10-01

    Full Text Available Todos en mayor o menor medida asociamos el nombre de Lewis Carrolla la literatura, sobre todo a la de temática infantil, con títulos a sus espaldas como Alicia en el País de las Maravillas, Alicia a través del espejo, o La Caza del Snark. Pero además de literato, Lewis Carrol fue un hombre con bastantes inquietudes en torno a la matemática, la lógica y el pensamiento filosófico. Pero no todo el mundo es conocedor de su faceta como creativo en el campo de los juegos. Rendezvous es una de sus más sorprendentes invenciones,un juego de inteligencia para todos los públicos, cuyas directrices hacen de él un entretenimiento bastante original.

  7. Ermakov–Lewis invariants and Reid systems

    Energy Technology Data Exchange (ETDEWEB)

    Mancas, Stefan C., E-mail: stefan.mancas@erau.edu [Department of Mathematics, Embry-Riddle Aeronautical University, Daytona Beach, FL 32114-3900 (United States); Rosu, Haret C., E-mail: hcr@ipicyt.edu.mx [IPICyT, Instituto Potosino de Investigacion Cientifica y Tecnologica, Camino a la presa San José 2055, Col. Lomas 4a Sección, 78216 San Luis Potosí, S.L.P. (Mexico)

    2014-06-13

    Reid's mth-order generalized Ermakov systems of nonlinear coupling constant α are equivalent to an integrable Emden–Fowler equation. The standard Ermakov–Lewis invariant is discussed from this perspective, and a closed formula for the invariant is obtained for the higher-order Reid systems (m≥3). We also discuss the parametric solutions of these systems of equations through the integration of the Emden–Fowler equation and present an example of a dynamical system for which the invariant is equivalent to the total energy. - Highlights: • Reid systems of order m are connected to Emden–Fowler equations. • General expressions for the Ermakov–Lewis invariants both for m=2 and m≥3 are obtained. • Parametric solutions of the Emden–Fowler equations related to Reid systems are obtained.

  8. Lewis Information Network (LINK): Background and overview

    Science.gov (United States)

    Schulte, Roger R.

    1987-01-01

    The NASA Lewis Research Center supports many research facilities with many isolated buildings, including wind tunnels, test cells, and research laboratories. These facilities are all located on a 350 acre campus adjacent to the Cleveland Hopkins Airport. The function of NASA-Lewis is to do basic and applied research in all areas of aeronautics, fluid mechanics, materials and structures, space propulsion, and energy systems. These functions require a great variety of remote high speed, high volume data communications for computing and interactive graphic capabilities. In addition, new requirements for local distribution of intercenter video teleconferencing and data communications via satellite have developed. To address these and future communications requirements for the next 15 yrs, a project team was organized to design and implement a new high speed communication system that would handle both data and video information in a common lab-wide Local Area Network. The project team selected cable television broadband coaxial cable technology as the communications medium and first installation of in-ground cable began in the summer of 1980. The Lewis Information Network (LINK) became operational in August 1982 and has become the backbone of all data communications and video.

  9. Lewis' Educational and Research Collaborative Internship Program

    Science.gov (United States)

    Heyward, Ann; Gott, Susan (Technical Monitor)

    2004-01-01

    The Lewis Educational and Research Collaborative Internship Program (LERCIP) is a collaborative undertaking by the Office of Educational Programs at NASA Glenn Research Center at Lewis Field (formerly NASA Lewis Research Center) and the Ohio Aerospace Institute. This program provides 10-week internships in addition to summer and winter extensions if funding is available and/or is requested by mentor (no less than 1 week no more than 4 weeks) for undergraduate/graduate students and secondary school teachers. Students who meet the travel reimbursement criteria receive up to $500 for travel expenses. Approximately 178 interns are selected to participate in this program each year and begin arriving the fourth week in May. The internships provide students with introductory professional experiences to complement their academic programs. The interns are given assignments on research and development projects under the personal guidance of NASA professional staff members. Each intern is assigned a NASA mentor who facilitates a research assignment. In addition to the research assignment, the summer program includes a strong educational component that enhances the professional stature of the participants. The educational activities include a research symposium and a variety of workshops, and lectures. An important aspect of the program is that it includes students with diverse social, cultural and economic backgrounds. The purpose of this report is to document the program accomplishments for 2004.

  10. A rainfall-based mechanism to regulate the release of water from Ranger uranium mine

    International Nuclear Information System (INIS)

    Carter, M.W.

    1989-01-01

    The far north of Australia (the Top End) has a monsoon-like climate. This wet-dry climate presents problems in water management for mining operations. These problems are exacerbated for the Ranger uranium mine at Jabiru due to the need to protect the environment of the surrounding Kakadu National Park, particularly the major wetland system downstream of the Ranger mine. An analysis of rainfall records for the wet-dry tropics of the far north of Australia is presented. A probability curve of the ratio between rainfall at a given date and rainfall at the year end, has been produced from actual data and can be used with a normalized curve to set levels of confidence of predicted rainfall being exceeded. The results of this analysis are used to develop a regulatory mechanism to limit release of waste water from a uranium mine to particularly wet years in accordance with the Australian Government's environmental protection policy. 19 refs., 11 tabs., 17 figs

  11. Non-radiological contaminants from uranium mining and milling at Ranger, Jabiru, Northern Territory, Australia.

    Science.gov (United States)

    Noller, B N

    1991-10-01

    Protection from the hazards from radioactivity is of prime importance in the management of uranium mine and mill wastes. Such wastes also contain non-radiological contaminants (heavy metals, acids and neutralising agents) which give rise to potential long-term health and environmental hazards and short-term hazards to the aquatic ecosystem, e.g. as a result of release of waste water. This study seeks to identify non-radiological contaminants (elements) transferred to waste water at the Ranger uranium mine/mill complex at Jabiru, which are likely to hazardous to the aquatic environment.The two principal sources of contaminants are: (i) ore and waste rock mobilised from mining; and (ii) process reagents used in the milling and mineral extraction process. These substances may or may not already be present in the natural environment but may lead to deleterious effects on the aquatic environment if increased above threshold levels.Rhenium, derived from the ore body, was found to be significantly enriched in waste water from Ranger, indicating its suitability as an indicator element for water originating from the mining and milling process, but only uranium, likewise derived from the ore, and magnesium, manganese and sulfur (as sulfate) from the milling process were found to be significant environmental contaminants.

  12. Fisheries Districts

    Data.gov (United States)

    Vermont Center for Geographic Information — The Fisheries districts data layer is part of a larger dataset that contains administrative boundaries for Vermont's Agency of Natural Resources. The dataset...

  13. Warden Districts

    Data.gov (United States)

    Vermont Center for Geographic Information — This dataset is a representation overlay of warden (areas of responsibility). The Vermont Warden Districts layer is part of a dataset that contains administrative...

  14. Forestry Districts

    Data.gov (United States)

    Vermont Center for Geographic Information — The Forestry Districts layer is part of a dataset that contains administrative boundaries for Vermont's Agency of Natural Resources. This is a layer file which...

  15. Wastewater Districts

    Data.gov (United States)

    Vermont Center for Geographic Information — The Wastewater districts layer is part of a larger dataset that contains administrative boundaries for Vermont's Agency of Natural Resources. The dataset includes...

  16. Wildlife Districts

    Data.gov (United States)

    Vermont Center for Geographic Information — The Wildlife Districts layer is part of a larger dataset contains administrative boundaries for Vermont's Agency of Natural Resources. The dataset includes feature...

  17. Park Districts

    Data.gov (United States)

    Vermont Center for Geographic Information — The Parks Districts layer is part of a dataset contains administrative boundaries for Vermont's Agency of Natural Resources. The dataset includes feature classes for...

  18. Ranger© - An Affordable, Advanced, Next-Generation, Dual-Pol, X-Band Weather Radar

    Science.gov (United States)

    Stedronsky, Richard

    2014-05-01

    The Enterprise Electronics Corporation (EEC) Ranger© system is a new generation, X-band (3 cm), Adaptive Polarization Doppler Weather Surveillance Radar that fills the gap between high-cost, high-power traditional radar systems and the passive ground station weather sensors. Developed in partnership with the University of Oklahoma Advanced Radar Research Center (ARRC), the system uses relatively low power solid-state transmitters and pulse compression technology to attain nearly the same performance capabilities of much more expensive traditional radar systems. The Ranger© also employs Adaptive Dual Polarization (ADP) techniques to allow Alternating or Simultaneous Dual Polarization capability with total control over the transmission polarization state using dual independent coherent transmitters. Ranger© has been designed using the very latest technology available in the industry and the technical and manufacturing experience gained through over four decades of successful radar system design and production at EEC. The entire Ranger© design concept emphasizes precision, stability, reliability, and value using proven solid state technology combined with the most advanced motion control system ever conceived for weather radar. Key applications include meteorology, hydrology, aviation, offshore oil/gas drilling, wind energy, and outdoor event situational awareness.

  19. Social assessment for the Wenatchee National Forest wildfires of 1994: targeted analysis for the Leavenworth, Entiat, and Chelan Ranger Districts.

    Science.gov (United States)

    Matthew S. Carroll; Angela J. Findley; Keith A. Blatner; Sandra Rodriguez Mendez; Steven E. Daniels; Gregg B. Walker

    2000-01-01

    A purposive social assessment across three communities explored reactions of local residents to wildfires in the Wenatchee National Forest in north-central Washington. Research concentrated on identifying the diversity of fundamental beliefs and values held by local residents about wildfire and forest management. Particular emphasis was given to investigating community...

  20. 75 FR 5758 - Bridger-Teton National Forest, Big Piney Ranger District, WY; Piney Creeks Vegetation Treatment

    Science.gov (United States)

    2010-02-04

    ... analysis area is approximately 20,000 acres within this watershed and includes the creeks of South, Middle... and for further site specific analysis of effects. It is approximately 25 miles west of Big Piney, Wyoming in the Green River drainage, on the east slope of the Wyoming range. All lands within the analysis...

  1. 75 FR 5941 - Umatilla National Forest, Walla Walla Ranger District, Walla Walla, WA; Cobbler II Timber Sale...

    Science.gov (United States)

    2010-02-05

    ... haul routes, non-commercial thinning, hardwood restoration, meadow restoration, and landscape... of Elgin, Oregon, is approximately 20 miles to the southwest. Troy and Eden Bench Wildland Urban... provide additional coarse woody debris. Landscape Prescribed Fire--Landscape prescribed fire would occur...

  2. 77 FR 4757 - Ochoco National Forest, Lookout Mountain Ranger District; Oregon; McKay Fuels and Vegetation...

    Science.gov (United States)

    2012-01-31

    ... interested and affected people may participate and contribute to the final decision. DATES: Comments...: Changes in tree species compositions. A reduction in late and old structured forest. A reduction in open... forest raptors and big game. Economics. In the current economy, markets for wood products are severely...

  3. 77 FR 26733 - Uinta-Wasatch-Cache National Forest; Evanston-Mountain View Ranger District; Utah; Smiths Fork...

    Science.gov (United States)

    2012-05-07

    ... process or judicial review. Comments received in response to this solicitation, including names and... respondent with standing to participate in the objection process associated with this project under the HFRA or judicial review. FOR FURTHER INFORMATION CONTACT: Pete Gomben, Environmental Coordinator, at 801...

  4. 78 FR 33047 - Humboldt-Toiyabe National Forest, Carson Ranger District Mt. Rose Ski Tahoe-Atoma Area...

    Science.gov (United States)

    2013-06-03

    ... Mt. Rose Ski Tahoe--Atoma Area Environmental Impact Statement AGENCY: Forest Service, USDA. ACTION... the effects of a proposal from Mt. Rose Ski Tahoe (Mt. Rose) to expand its lift and terrain network. The project is located approximately 12 miles west of the intersection of Mt. Rose Highway (Nevada...

  5. 75 FR 71666 - Bend/Ft. Rock Ranger District; Deschutes National Forest; Deschutes County, OR; West Bend...

    Science.gov (United States)

    2010-11-24

    ... management is intended to move the project area towards the HRV which will benefit certain focal species that... miles of biking, hiking, snowmobile, crosscountry skiing, and snowshoeing trails. The Forest is the...

  6. 76 FR 23273 - Bend/Ft. Rock Ranger District; Deschutes National Forest; Deschutes County, Oregon; Mt. Bachelor...

    Science.gov (United States)

    2011-04-26

    ... for utilization of wood products from forest management projects and associated economic benefits. 5... only one dedicated hiking trail and one mountain bike trail, located in the base and Nordic areas. Increased hiking and biking infrastructure is needed to meet demand, increase year-round utilization of...

  7. 75 FR 65608 - Flathead National Forest-Swan Lake Ranger District, Montana; Wild Cramer Forest Health and Fuels...

    Science.gov (United States)

    2010-10-26

    ... reserves, seed tree with reserves, and shelterwood with reserves) on 3,489 acres and intermediate harvest... initiates the scoping process, which guides the development of the environmental impact statement. Public... 500 entities), as well as other interested parties. A field trip is being offered as part of the...

  8. 76 FR 2878 - Six Rivers National Forest, Mad River Ranger District, CA; Buck Mountain Vegetation and Fuel...

    Science.gov (United States)

    2011-01-18

    ... with high fuel loadings. (2) The majority of the planning area occurs within the Wildland Urban... extend the availability of forage and reduce the rate of spread of wildfire. (4) The Van Duzen River... cutting, mastication, road-side chipping, prescribed fire, hand piling, biomass/fuelwood utilization...

  9. 75 FR 20979 - Six Rivers National Forest, Mad River Ranger District, Ruth, CA, Beaverslide Timber Sale and Fuel...

    Science.gov (United States)

    2010-04-22

    ..., and policies in making the decision and stating the rationale in the Record of Decision. Scoping... supply for local economies; and Reduce fuel loading in strategic locations to improve fire protection and... loading would be reduced on approximately 2,700 acres within 20 fuel treatment units and 7 strategic fuel...

  10. 76 FR 26239 - Umatilla National Forest, Walla Walla Ranger District, Oregon, Cobbler II Timber Sale and Fuels...

    Science.gov (United States)

    2011-05-06

    ...; 1415 W. Rose; Walla Walla, Washington 99362. FOR FURTHER INFORMATION CONTACT: Kimpton Cooper, 509-522... can be found on the Umatilla National Forest Web site at ( http://www.fs.fed.us/nepa/nepa_test/fs-usda...

  11. 77 FR 27013 - Ketchikan-Misty Fiords Ranger District; Tongass National Forest; Alaska; Saddle Lakes Timber Sale...

    Science.gov (United States)

    2012-05-08

    ... Federal Information Relay Service (FIRS) at 1-800-877-8339 between 8 a.m. and 8 p.m., Eastern Time, Monday... transition to a sustainable wood product industry based on young-growth managment. The underlying need for... provide their comments at such times and in such manner that they are useful to the agency's preparation...

  12. 75 FR 19936 - Medicine Bow-Routt National Forests, Brush Creek/Hayden Ranger District Saratoga, WY

    Science.gov (United States)

    2010-04-16

    ... areas. In areas managed to produce commercial wood products, it is necessary to salvage merchantable... remove dead and dying trees that are posing a public safety hazard in high priority areas. The proposal...-killed) dead and dying trees; reduce hazardous fuels; provide forest products; promote forest...

  13. Ablative Material Testing at Lewis Rocket Lab

    Science.gov (United States)

    1997-01-01

    The increasing demand for a low-cost, reliable way to launch commercial payloads to low- Earth orbit has led to the need for inexpensive, expendable propulsion systems for new launch vehicles. This, in turn, has renewed interest in less complex, uncooled rocket engines that have combustion chambers and exhaust nozzles fabricated from ablative materials. A number of aerospace propulsion system manufacturers have utilized NASA Lewis Research Center's test facilities with a high degree of success to evaluate candidate materials for application to new propulsion devices.

  14. An analysis of the preliminary water management proposal for the Ranger Uranium Mine

    International Nuclear Information System (INIS)

    Gibson, D.K.

    1980-07-01

    Some of the problems expected to arise as a result of contamination of rainfall run-off by the ore and waste rock heaps of the Ranger Uranium Mine, at Jabiru in the Northern Territory of Australia, have been re-examined. A computer program has been written to estimate the quantity of run-off water resulting from any given rainfall pattern. The program was calibrated against measured stream flows in Gulungul Creek; it was then applied to the two major catchment areas surrounding the mine site, and estimates of the quantity and quality of discharge water were made. The effects of the discharge are discussed in relation to the levels tolerable to fish and, in the case of radium, permitted as uptake by humans. A possible modification to the water management plan, which would increase the time for sedimentation before discharge, is suggested

  15. Investigation of tailings water leak at the Ranger uranium mine. Supervising Scientist report 153

    International Nuclear Information System (INIS)

    2000-01-01

    The purpose of this report has been to investigate and report on the leak of water from the Tailings Water Return Pipe at the Ranger uranium mine during the 1999/2000 Wet season with specific reference to: the origin of the leak and the adequacy of remediation measures taken to prevent similar occurrences in the future; the extent to which the people and the environment of Kakadu National Park have been adversely affected by the leak and the extent to which Energy Resources of Australia has complied with the reporting requirements specified in the Environmental Requirements. It describes the outcomes of the investigation and makes recommendations to address deficiencies identified in the environmental management systems at Ranger and in the supervisory and regulatory regimes applied to Ranger by the Supervising Scientist and NTDME. It has been established that the volume of water that leaked from the tailings water return pipeline was about 2000 cubic metres during the 1999/2000 Wet season. Of this, only a small fraction, about 85 cubic metres, entered the culvert which flows to thc Corridor Creek Wetlands. The remainder was collected in the tailings corridor sump and returned to the water management system. The failure of the pipeline to contain tailings water would not on itself normally have resulted in the discharge of this water to the external environment. That the leaked water did reach the external environment is due to a failure of the bunded corridor system to fully contain any spilled water. The cause of this failure was that the engineered structure between the roadway and a culvert that drains water from the nearby waste rock dump was not impermeable.The statutory monitoring program has been found to be deficient in two ways. First, other than visual inspection, it has not been designed to include monitoring locations within secondary containment systems that would indicate the failure of primary containment systems. In the present case, no statutory

  16. Some design and operating aspects of the Ranger uranium mine treatment plant

    International Nuclear Information System (INIS)

    Baily, P.A.

    1984-01-01

    Environmental considerations were key factors in the design of the Ranger Uranium Mines treatment plant. The mine is located adjacent to the Kakadu National Park and has an average rainfall of 1.6m per annum. No contaminated water or liquid effluents are to be released from the project area and thus water management is a key design and operating fact. Particulate and gas emission criteria influenced design as did occupational hygiene factors (dust, radon, housekeeping, maintenance access). Equipment selection and engineering standards were conservative and resulted in the plant attaining design performance in less than three months from the date of commissioning. A number of mechanical and operational problems were experienced. However, none of these problems have had a significant effect on production

  17. Interview with Smithsonian NASM Spacesuit Curator Dr. Cathleen Lewis

    Science.gov (United States)

    Lewis, Cathleen; Wright, Rebecca

    2012-01-01

    Dr. Cathleen Lewis was interviewed by Rebecca Wright during the presentation of an "Interview with Smithsonian NASM Spacesuit Curator Dr. Cathleen Lewis" on May 14, 2012. Topics included the care, size, and history of the spacesuit collection at the Smithsonian and the recent move to the state-of-the-art permanent storage facility at the Udvar-Hazy facility in Virginia.

  18. LEWIS BINFORD AND HIS MORAL MAJORITY (Lewis Binford y su mayoría moral

    Directory of Open Access Journals (Sweden)

    Alice Beck Kehoe

    2011-06-01

    Full Text Available This essay looks at the late Lewis Binford’s career from the standpoint of sociology of science. His thinking and manner reflect his socialization in Virginia Baptist subculture. As convinced of his authority on science as Jerry Falwell was of his authority on Biblical morality, Lewis Binford and his third wife Sally Rosen Binford excited a group of 1960s students to follow Lewis in an outmoded version of science (hypothetico-deductive and in trusting statistics. The “frames of reference” he laboriously constructed are naïve on environmental interpretation and, because he expressed contempt for “political” aspects of archaeology, fail to take into account effects of colonialism. His work is often scientistic, in the “modern” mode that historian Dorothy Ross describes as characteristic of twentieth-century American social sciences. ESPAÑOL: En este ensayo se analiza la etapa final de la carrera de Lewis Binford desde el punto de vista de la sociología de la ciencia. Su pensamiento refleja su socialización en el seno de la subcultura de la Virginia baptista. Tan convencido de su autoridad en la ciencia como Jerry Falwell lo fuera sobre la moralidad bíblica, Lewis Binford y su tercera esposa Sally Rosen Binford animaron a un grupo estudiantes de los sesenta a seguir a Lewis a través de una versión anticuada de la ciencia (hipotético-deductiva y a confiar en la estadística. Los “marcos de referencia” que laboriosamente construyó son ingenuos en la interpretación del medio ambiente y, como expresó el desprecio por los aspectos “políticos” de la arqueología, no tienen en cuenta los efectos del colonialismo. Su trabajo es a menudo cientificista, en el sentido “moderno” que la historiadora Dorothy Ross describe como una característica de las ciencias sociales norteamericanas del siglo XX.

  19. Nuclear pursuits: The scientific biography of Wilfrid Bennett Lewis

    International Nuclear Information System (INIS)

    Fawcett, R.

    1994-01-01

    The scientific life of Wilfrid Bennett Lewis. The biography covers Lewis's role in the development of radar, his tenure as the Chief Superintendent of the Telecommunications Research Establishment at Malvern through his heading of the then fledgling Canadian nuclear research facility in Chalk River, Ontario. Lewis's drive, intelligence, and remarkable organizational skills placed him at the forefront of Canada's nuclear program. His influence lead to a collaboration between Atomic Energy of Canada Limited and Ontario Hydro that ultimately resulted in the development of the CANDU reactor. His influence was also profound in the near by town of Deep River with one prime legacy being the W.B. Lewis Library. Lewis's bibliography is included in the biography

  20. [Clinical Neuropsychology of Dementia with Lewy Bodies].

    Science.gov (United States)

    Nagahama, Yasuhiro

    2016-02-01

    Dementia with Lewy bodies (DLB) shows lesser memory impairment and more severe visuospatial disability than Alzheimer disease (AD). Although deficits in both consolidation and retrieval underlie the memory impairment, retrieval deficit is predominant in DLB. Visuospatial dysfunctions in DLB are related to the impairments in both ventral and dorsal streams of higher visual information processing, and lower visual processing in V1/V2 may also be impaired. Attention and executive functions are more widely disturbed in DLB than in AD. Imitation of finger gestures is impaired more frequently in DLB than in other mild dementia, and provides additional information for diagnosis of mild dementia, especially for DLB. Pareidolia, which lies between hallucination and visual misperception, is found frequently in DLB, but its mechanism is still under investigation.

  1. Superconducting microwave electronics at Lewis Research Center

    Science.gov (United States)

    Warner, Joseph D.; Bhasin, Kul B.; Leonard, Regis F.

    Over the last three years, NASA Lewis Research Center has investigated the application of newly discovered high temperature superconductors to microwave electronics. Using thin films of YBa2Cu3O7-delta and Tl2Ca2Ba2Cu3Ox deposited on a variety of substrates, including strontium titanate, lanthanum gallate, lanthanum aluminate and magnesium oxide, a number of microwave circuits have been fabricated and evaluated. These include a cavity resonator at 60 GHz, microstrip resonators at 35 GHz, a superconducting antenna array at 35 GHz, a dielectric resonator at 9 GHz, and a microstrip filter at 5 GHz. Performance of some of these circuits as well as suggestions for other applications are reported.

  2. Superconducting Microwave Electronics at Lewis Research Center

    Science.gov (United States)

    Warner, Joseph D.; Bhasin, Kul B.; Leonard, Regis F.

    1991-01-01

    Over the last three years, NASA Lewis Research Center has investigated the application of newly discovered high temperature superconductors to microwave electronics. Using thin films of YBa2Cu3O7-delta and Tl2Ca2Ba2Cu3Ox deposited on a variety of substrates, including strontium titanate, lanthanum gallate, lanthanum aluminate and magnesium oxide, a number of microwave circuits have been fabricated and evaluated. These include a cavity resonator at 60 GHz, microstrip resonators at 35 GHz, a superconducting antenna array at 35 GHz, a dielectric resonator at 9 GHz, and a microstrip filter at 5 GHz. Performance of some of these circuits as well as suggestions for other applications are reported.

  3. Lewis-Sumner syndrome and Tangier disease.

    Science.gov (United States)

    Théaudin, Marie; Couvert, Philippe; Fournier, Emmanuel; Bouige, Daniel; Bruckert, Eric; Perrotte, Paul; Vaschalde, Yvan; Maisonobe, Thierry; Bonnefont-Rousselot, Dominique; Carrié, Alain; Le Forestier, Nadine

    2008-07-01

    To report unusual electrophysiologic data in a patient with Tangier disease in an effort to better understand the pathophysiologic features of the peripheral nerve lesions in this disease. Case report. A 15-year-old girl had subacute onset of asymmetric neuropathy with persistent conduction block, resembling Lewis-Sumner syndrome. Electrophysiologic data in Tangier disease. After initially unsuccessful treatment with intravenously administered immunoglobulins, the finding of an abnormal lipid profile led to the diagnosis of Tangier disease due to the R587W mutation in the adenotriphosphate-binding cassette transporter-1 gene (ABCA1) (OMIM 9q22-q31). Conduction block, which is the electrophysiologic hallmark of focal demyelination, can be present in Tangier disease. It could be induced by focal nerve ischemia or by preferential lipid deposition in the paranodal regions of myelinated Schwann cells. The presence of a conduction block in Tangier disease may lead to a misdiagnosis of dysimmune neuropathy.

  4. The application of image processing in the measurement for three-light-axis parallelity of laser ranger

    Science.gov (United States)

    Wang, Yang; Wang, Qianqian

    2008-12-01

    When laser ranger is transported or used in field operations, the transmitting axis, receiving axis and aiming axis may be not parallel. The nonparallelism of the three-light-axis will affect the range-measuring ability or make laser ranger not be operated exactly. So testing and adjusting the three-light-axis parallelity in the production and maintenance of laser ranger is important to ensure using laser ranger reliably. The paper proposes a new measurement method using digital image processing based on the comparison of some common measurement methods for the three-light-axis parallelity. It uses large aperture off-axis paraboloid reflector to get the images of laser spot and white light cross line, and then process the images on LabVIEW platform. The center of white light cross line can be achieved by the matching arithmetic in LABVIEW DLL. And the center of laser spot can be achieved by gradation transformation, binarization and area filter in turn. The software system can set CCD, detect the off-axis paraboloid reflector, measure the parallelity of transmitting axis and aiming axis and control the attenuation device. The hardware system selects SAA7111A, a programmable vedio decoding chip, to perform A/D conversion. FIFO (first-in first-out) is selected as buffer.USB bus is used to transmit data to PC. The three-light-axis parallelity can be achieved according to the position bias between them. The device based on this method has been already used. The application proves this method has high precision, speediness and automatization.

  5. Application of best practicable technology to water management at Ranger Uranium mine: report of the technical working group

    International Nuclear Information System (INIS)

    1986-12-01

    An assessment is made of best practicable technology (BPT) as applied to the water management system of Ranger Uranium Mines for the period 1986-91. A specification of BPT cannot be made for the indefinite future because major changes in operation of the mine may occur which could have an impact on future water management. It is for these reasons that the period of detailed assessment has been limited to the next 5 years. For the purposes of the report, BPT is considered to be that technology relevant to the Ranger project which produced the minimum environmental pollution and degradation that can reasonably be achieved, having regard to a number of technical factors, including practice in uranium mining elsewhere in the world, cost, evidence of detriment or lack of it, project location and the age and effectiveness of equipment and facilities at Ranger. Three options are presented, in order of preference: no prohibition on release to Magela Creek, limitation on frequency of release to Magela Creek and prohibition on release to Magela Creek

  6. C. S. Lewis, Reluctant Convert and (not so Ordinary Anglican

    Directory of Open Access Journals (Sweden)

    Mănăstireanu Dănuţ

    2014-12-01

    Full Text Available After some passing considerations on the reception of Lewis in Romania, the present paper discusses the role played by Anglicanism in the late personal commitment of C.S. Lewis to the Christian faith, after years of atheism, scepticism, and agnosticism. It argues that in fact Anglicanism contributed very little to Lewis’s (reconversion to Christianity. Furthermore, the paper agrees with the generally accepted idea that the particular calling that Lewis felt he had, that of being a Christian apologist, made him wary of being associated with the defence of any specific Christian tradition. In virtue of this special calling, Lewis also reacted quite strongly against certain aspects of Anglicanism, like, for instance, the ordination of women to priesthood, which he perceived as an obstacle to ecumenism and, implicitly, to an effective defence of the Christian faith in the public arena. In spite of all this, there is little doubt that Lewis has fully and unreservedly adopted Anglicanism as his preferred version of Christianity. From this particular stance, the life and ministry of C.S. Lewis made a huge public impact in the twentieth century and beyond. In light of the undeniable influence he had on the intellectual and religious scene in the last hundred years, one may ask not so much how Anglican was Lewis, but, rather, ‘why isn’t Anglicanism more like Lewis’.

  7. Mine planning and scheduling at Ranger Uranium Mine - environmental requirements and economics

    International Nuclear Information System (INIS)

    Bath, L.J.

    1984-01-01

    Ranger Uranium Mines operates an open cut located in the Northern Territory. Strict environmental controls govern all operations and the water management requirements have the greatest impact on mine planning. The two main goals of planning are to provide mill feed and to mine sufficient suitable quality waste rock for ongoing construction of the tailings dam. Early planning concentrated on staged development of the pit to provide access to as much ore as possible for a given amount of development. All waste was considered to be suitable construction material. Grade control of crusher feed was the main problem in planning, as wide variations occur in ore grade over relatively short distances. Water management for the site operates a 'no release' system for contaminated waters. Design storage has proven inadequate, and the open cut has been used as the extra storage. As construction of future stages of the tailings dam requires non-mineralised rock materials which meet specific quality criteria, the mine has had to re-examine long term planning and pit development strategies. This has entailed the collection of much data not required under normal mining conditions, such as the assaying of waste drill core. The overall impact on mine planning of the environmental regulations has been to alter the philosophy of earlier planning, making it necessary to create a new strategy for pit development with the accent on exposing waste

  8. NASA Lewis Research Center's materials and structures division

    International Nuclear Information System (INIS)

    Weymueller, C.R.

    1976-01-01

    Research activities at the NASA Lewis Research Center on materials and structures are discussed. Programs are noted on powder metallurgy superalloys, eutectic alloys, dispersion strengthened alloys and composite materials. Discussions are included on materials applications, coatings, fracture mechanics, and fatigue

  9. Is It Lewy Body Dementia or Something Else?

    Science.gov (United States)

    ... Options Join the fight against LBD! Donate Is It LBD or Something Else? Early and accurate diagnosis ... dementia with Lewy bodies’ (DLB). Symptoms that differentiate it from Alzheimer’s include unpredictable levels of cognitive ability, ...

  10. I-Metaiodobenzylguanidine Myocardial Scintigraphy in Lewy Body-Related Disorders: A Literature Review

    Directory of Open Access Journals (Sweden)

    Eun Joo Chung

    2015-05-01

    Full Text Available Lewy body-related disorders are characterized by the presence of Lewy bodies and Lewy neurites, which have abnormal aggregations of α-synuclein in the nigral and extranigral areas, including in the heart. 123I-metaiodobenzylguanidine (MIBG scintigraphy is a well-known tool to evaluate cardiac sympathetic denervation in the Lewy body-related disorders. MIBG scintigraphy showed low uptake of MIBG in the Lewy body-related disorders, including Parkinson’s disease, dementia with Lewy bodies, pure autonomic failure and rapid eye movement sleep behavior disorder. This review summarizes previous results on the diagnostic applications of MIBG scintigraphy in Lewy body-related disorders.

  11. Lewis Research Center space station electric power system test facilities

    Science.gov (United States)

    Birchenough, Arthur G.; Martin, Donald F.

    1988-01-01

    NASA Lewis Research Center facilities were developed to support testing of the Space Station Electric Power System. The capabilities and plans for these facilities are described. The three facilities which are required in the Phase C/D testing, the Power Systems Facility, the Space Power Facility, and the EPS Simulation Lab, are described in detail. The responsibilities of NASA Lewis and outside groups in conducting tests are also discussed.

  12. Chiral lewis Acid catalysis in nitrile oxide cycloadditions.

    Science.gov (United States)

    Sibi, Mukund P; Itoh, Kennosuke; Jasperse, Craig P

    2004-05-05

    We describe examples of highly regio- and enantioselective nitrile oxide cycloadditions to unsaturated alkenes using substoichiometric amounts of a chiral Lewis acid. Pyrazolidinones proved to be effective achiral templates in the cycloadditions providing C-adducts typically in >30:1 selectivity and 80-99% ee. To avoid potential problems involving coordination of the Lewis acid by amine bases, we have devised a novel method for the generation of unstable nitrile oxides from hydroximinoyl chlorides using Amberlyst 21 as the base.

  13. Tribute to Erwin Felix Lewy-Bertaut

    International Nuclear Information System (INIS)

    2006-01-01

    Erwin Lewy (alias Felix Bertaut) was born in 1913 in Germany, he emigrated to France where he undertook graduate studies in chemistry. Then, he joined the powder central laboratory where he learnt how to use international tables for structure determination. His thesis work was the X-ray study of the statistical distribution of the size of iron grains. The method Bertaut developed is still a reference in powder granulometry. Bertaut was also interested in the nascent neutron diffraction method and he flew to the United-States to improve his knowledge on this topic. Felix Bertaut created the neutron diffraction laboratory in the atomic research center in Grenoble and later he headed the CNRS' crystallography laboratory till 1982. Felix Bertaut and his laboratories became internationally renowned in crystallography, neutron diffraction and magnetism. He favored the scientific cooperation between France and Germany that led to the creation of the Laue-Langevin Institute (ILL). The ILL became European and was a key partner for building the European Synchrotron Facility (ESRF) in Grenoble. Bertaut was elected as a full member of the French Academy of Sciences in 1979, he died in 2003. (A.C.)

  14. Lewis Research Center R and D Facilities

    Science.gov (United States)

    1991-01-01

    The NASA Lewis Research Center (LeRC) defines and develops advanced technology for high priority national needs. The work of the Center is directed toward new propulsion, power, and communications technologies for application to aeronautics and space, so that U.S. leadership in these areas is ensured. The end product is knowledge, usually in a report, that is made fully available to potential users--the aircraft engine industry, the energy industry, the automotive industry, the space industry, and other NASA centers. In addition to offices and laboratories for almost every kind of physical research in such fields as fluid mechanics, physics, materials, fuels, combustion, thermodynamics, lubrication, heat transfer, and electronics, LeRC has a variety of engineering test cells for experiments with components such as compressors, pumps, conductors, turbines, nozzles, and controls. A number of large facilities can simulate the operating environment for a complete system: altitude chambers for aircraft engines; large supersonic wind tunnels for advanced airframes and propulsion systems; space simulation chambers for electric rockets or spacecraft; and a 420-foot-deep zero-gravity facility for microgravity experiments. Some problems are amenable to detection and solution only in the complete system and at essentially full scale. By combining basic research in pertinent disciplines and generic technologies with applied research on components and complete systems, LeRC has become one of the most productive centers in its field in the world. This brochure describes a number of the facilities that provide LeRC with its exceptional capabilities.

  15. Lewy body dementia--clinical, pathological and neurochemical interconnections.

    Science.gov (United States)

    Perry, R; McKeith, I; Perry, E

    1997-01-01

    Senile dementia of Lewy body type or Lewy body dementia (SDLT or LBD) is defined as a Lewy body associated disease presenting in the elderly primarily with dementia with variable extrapyramidal disorder. Characteristic clinical symptoms include fluctuating cognitive impairment, psychotic features such as hallucinations and a particular sensitivity to neuroleptic medication. Although apolipoprotein e4 allele is increased 2-3 fold in SDLT (as in Alzheimer's disease) and beta-amyloidosis occurs in most cases, the most robust neurobiological correlate of the dementia so far identified appears to be extensive cholinergic deficits in the neocortex. This is consistent with previously reported correlations between cortical cholinergic activity and dementia in Parkinson's disease (PD) and Alzheimer's disease. There is also a significant interaction between the density of limbic cortical Lewy bodies and dementia in both SDLT and PD, although the cortical neuronal population affected remains to be identified. Cortical Lewy body density is positively correlated with the age of disease onset in PD and SDLT. This may account for the increased incidence of psychiatric syndromes, as opposed to extrapyramidal disorder in Lewy body disease with advancing age as may age-related loss of cholinergic activity in cortical areas such as the hippocampus.

  16. District heating

    International Nuclear Information System (INIS)

    Hansen, L.

    1993-01-01

    The environmental risks and uncertainties of a high-energy future are disturbing and give rise to several reservations concerning the use of fossil fuels. A number of technologies will help to reduce atmospheric pollution. In Denmark special importance is attached to the following: Energy conservation. Efficient energy conversion. Renewable energy sources. District heating, combined production of heat and power. Many agree that district heating (DH), produced by the traditional heat-only plant, and combined heat and power (CHP) have enormous potential when considering thermal efficiency and lowered environmental impacts: The basic technology of each is proven, it would be relatively simple to satisfy a substantial part of the energy demand, and their high efficiencies mean reduced pollution including greenhouse gas emissions. This is especially important in high population density areas - the obviously preferred sites for such energy generation. Compared with individual heating DH can provide a community with an operationally efficient and most often also an economically competitive heat supply. This is particularly true under the circumstances where the DH system is supplied from CHP plants. Their use results in very substantial improvements in overall efficiency. Further environmental improvements arise from the reduced air pollution obtainable in reasonably large CHP plants equipped with flue gas cleaning to remove particles, sulphur dioxide, and nitrogen acids. As a consequence of these considerations, DH plays an important role in fulfilling the space and water heating demand in many countries. This is especially the case in Denmark where this technology is utilised to a very great extent. Indeed, DH is one of the reasons why Denmark has relatively good air quality in the cities. (au)

  17. Capgras syndrome in Dementia with Lewy Bodies.

    Science.gov (United States)

    Thaipisuttikul, Papan; Lobach, Iryna; Zweig, Yael; Gurnani, Ashita; Galvin, James E

    2013-05-01

    Capgras syndrome is characterized by the recurrent, transient belief that a person has been replaced by an identical imposter. We reviewed clinical characteristics of Dementia with Lewy Bodies (DLB) patients with Capgras syndrome compared to those without Capgras. We identified 55 consecutive DLB patients (11 cases with Capgras syndrome (DLB-C) and 44 cases without evidence of Capgras (DLB). Semi-structured interviews with the patient and an informant, neurological exams, and neuropsychological testing were performed. Caregivers were assessed for caregiver burden and depression. Primary comparisons were made between DLB-C and DLB. Exploratory analyses using stepwise logistic regression and bootstrap analyses were performed to determine clinical features associated with Capgras. DLB-C patients experienced more visual hallucinations and self-reported anxiety, had higher scores on the Neuropsychiatric Inventory, and were less likely to be treated with cholinesterase inhibitors at time of initial evaluation. Extrapyramidal symptoms and depression were not associated with Capgras. Caregivers of DLB-C patients had higher caregiver burden. DLB-C was associated with self-reported anxiety (OR = 10.9; 95% CI = 2.6-47.6). In a bootstrap analysis, clinical findings that were predictors of Capgras included visual hallucinations (log(OR) = 18.3; 95% CI = 17.9-19.3) and anxiety (log(OR) = 2.9; 95% CI = 0.31-20.2). Our study suggests that Capgras syndrome is common in DLB and usually occurs in the presence of anxiety and visual hallucinations, suggesting related etiopathogenesis. Early appreciation of Capgras syndrome may afford the opportunity to alleviate caregiver burden and improve patient and caregiver outcomes.

  18. Application of a catchment evolution model to the prediction of long-term erosion on the spoil heap at Ranger uranium mine. Supervising Scientist report 132

    International Nuclear Information System (INIS)

    Willgoose, G.

    1998-01-01

    There is a need to assess the long-term stability of engineered landforms associated with the rehabilitation of Ranger Uranium Mine, Northern Territory, Australia, as it is a requirement that mill tailings must be contained for periods in excess of 1000 years. The geomorphic model, SIBERIA, is calibrated on hydrology and erosion data collected by a combination of monitoring and rainfall simulation experiments on the waste rock dumps of Ranger. Preliminary analysis of Ranger's preferred above-grade and below-grade rehabilitation options suggests that erosion of the order of 7-8 m will occur on the structure in a period of 1000 years. This depth of erosion may be sufficient to compromise the integrity of the containment. It is shown that SIBERIA has significant advantages over steady-state erosion models. Suggestions are made for the design that will enhance the stability of the structure and extend the structural life of the containment

  19. Pareidolias: complex visual illusions in dementia with Lewy bodies.

    Science.gov (United States)

    Uchiyama, Makoto; Nishio, Yoshiyuki; Yokoi, Kayoko; Hirayama, Kazumi; Imamura, Toru; Shimomura, Tatsuo; Mori, Etsuro

    2012-08-01

    Patients rarely experience visual hallucinations while being observed by clinicians. Therefore, instruments to detect visual hallucinations directly from patients are needed. Pareidolias, which are complex visual illusions involving ambiguous forms that are perceived as meaningful objects, are analogous to visual hallucinations and have the potential to be a surrogate indicator of visual hallucinations. In this study, we explored the clinical utility of a newly developed instrument for evoking pareidolic illusions, the Pareidolia test, in patients with dementia with Lewy bodies-one of the most common causes of visual hallucinations in the elderly. Thirty-four patients with dementia with Lewy bodies, 34 patients with Alzheimer's disease and 26 healthy controls were given the Pareidolia test. Patients with dementia with Lewy bodies produced a much greater number of pareidolic illusions compared with those with Alzheimer's disease or controls. A receiver operating characteristic analysis demonstrated that the number of pareidolias differentiated dementia with Lewy bodies from Alzheimer's disease with a sensitivity of 100% and a specificity of 88%. Full-length figures and faces of people and animals accounted for >80% of the contents of pareidolias. Pareidolias were observed in patients with dementia with Lewy bodies who had visual hallucinations as well as those who did not have visual hallucinations, suggesting that pareidolias do not reflect visual hallucinations themselves but may reflect susceptibility to visual hallucinations. A sub-analysis of patients with dementia with Lewy bodies who were or were not treated with donepzil demonstrated that the numbers of pareidolias were correlated with visuoperceptual abilities in the former and with indices of hallucinations and delusional misidentifications in the latter. Arousal and attentional deficits mediated by abnormal cholinergic mechanisms and visuoperceptual dysfunctions are likely to contribute to the development

  20. Intralaminar nuclei of the thalamus in Lewy body diseases.

    Science.gov (United States)

    Brooks, Daniel; Halliday, Glenda M

    2009-02-16

    Although the intralaminar thalamus is a target of alpha-synuclein pathology in Parkinson's disease, the degree of neuronal loss in Lewy body diseases has not been assessed. We have used unbiased stereological techniques to quantify neuronal loss in intralaminar thalamic nuclei concentrating alpha-synuclein pathology (the anterodorsal, cucullar, parataenial, paraventricular, central medial, central lateral and centre-median/parafascicular complex) in different clinical forms of Lewy body disease (Parkinson's disease with and without dementia, and dementia with Lewy bodies, N=21) compared with controls (N=5). Associations were performed in the Lewy body cases between intralaminar cell loss and the main diagnostic clinical (parkinsonism, dementia, fluctuation in consciousness, and visual hallucinations) and pathological (Braak stage of Parkinson's disease) features of these diseases, as well as between cell loss and the scaled severity of the alpha-synuclein deposition within the intralaminar thalamus. As expected, significant alpha-synuclein accumulation occurred in the intralaminar thalamus in the cases with Lewy body disease. Pathology concentrated anteriorly and in the central lateral and paraventricular nuclei was related to the Braak stage of Parkinson's disease, ageing, and the presence of dementia. Across all types of Lewy body cases there was substantial atrophy and neuronal loss in the central lateral, cucullar and parataenial nuclei, and neuronal loss without atrophy in the centre-median/parafascicular complex. Cases with visual hallucinations showed a greater degree of atrophy of the cucullar nucleus, possibly due to amygdala denervation. The significant degeneration demonstrated in the intralaminar thalamus is likely to contribute to the movement and cognitive dysfunction observed in Lewy body disorders.

  1. A quantum inspired model of radar range and range-rate measurements with applications to weak value measurements

    Science.gov (United States)

    Escalante, George

    2017-05-01

    Weak Value Measurements (WVMs) with pre- and post-selected quantum mechanical ensembles were proposed by Aharonov, Albert, and Vaidman in 1988 and have found numerous applications in both theoretical and applied physics. In the field of precision metrology, WVM techniques have been demonstrated and proven valuable as a means to shift, amplify, and detect signals and to make precise measurements of small effects in both quantum and classical systems, including: particle spin, the Spin-Hall effect of light, optical beam deflections, frequency shifts, field gradients, and many others. In principal, WVM amplification techniques are also possible in radar and could be a valuable tool for precision measurements. However, relatively limited research has been done in this area. This article presents a quantum-inspired model of radar range and range-rate measurements of arbitrary strength, including standard and pre- and post-selected measurements. The model is used to extend WVM amplification theory to radar, with the receive filter performing the post-selection role. It is shown that the description of range and range-rate measurements based on the quantum-mechanical measurement model and formalism produces the same results as the conventional approach used in radar based on signal processing and filtering of the reflected signal at the radar receiver. Numerical simulation results using simple point scatterrer configurations are presented, applying the quantum-inspired model of radar range and range-rate measurements that occur in the weak measurement regime. Potential applications and benefits of the quantum inspired approach to radar measurements are presented, including improved range and Doppler measurement resolution.

  2. Soils and hydrology of the Ranger uranium mine land application site

    International Nuclear Information System (INIS)

    Willett, I.R.; Charters, C.J.; Bond, W.J.

    1992-01-01

    This paper describes the soils and hydrology of an area between Ranger Uranium Mine and Magela Creek, Northern Territory, which is being used for the disposal of retention pond water by irrigation. The soils of an alternative site are also described in less detail. The soil survey of the irrigated area indicated three mapping units differentiated on the basis of texture, colour depth, drainage and the presence of absence of ferricrete. The predominant soils in each unit were yellow earths, red earths and siliceous sands. All the soils had high (20-50%) gravel contents consisting of quartz and ferruginous materials. The gavel is expected to have little ability to retain solutes and therefore reduces the effectiveness of the bulk soil to retain solutes. The soils are generally low in clay (<20%) and organic matter <1%) and are acidic. The clay minerals were of the low activity types, predominantly kaolinite. Consequently the cation exchange capacities of the soils were very low indicating a limited capacity to retain cations. Preliminary calculations showed that the soils would be unable to retain all the cations in the applied water. In order to assess whether redox reactions are likely to be involved in the retention of radionuclides, the responses of the soils to saturation were tested in a laboratory experiment. The implications of these results for the retention of metals and radionuclides were discussed. All soils were found to have high permeabilities. Preliminary calculations showed that transmission of irrigation water to the water table would be rapid (less than 6 weeks). The soils of the alternative site were generally heavier and contained less gravel than those of the current irrigation site. They are likely to retain more solutes than the soils of the current irrigated area and may be better suited to land disposal of retention pond water. 20 refs., 6 tabs., 5 figs

  3. Lewy and his inclusion bodies: Discovery and rejection

    Directory of Open Access Journals (Sweden)

    Eliasz Engelhardt

    Full Text Available ABSTRACT Fritz Jacob Heinrich Lewy described the pathology of Paralysis agitans [Parkinson disease] and was the first to identify eosinophilic inclusion bodies in neurons of certain brain nuclei, later known as Lewy bodies, the pathological signature of the Lewy body diseases. In 1912, he published his seminal study, followed soon after by an update paper, and 10 years later, in 1923, by his voluminous book, where he exhaustively described the subject. The publication provided extensive information on the pathology of Paralysis agitans, and the entirely novel finding of eosinophilic inclusion bodies, which would become widely recognized and debated in the future. His discovery was acknowledged by important researchers who even named the structure after him. However, after his last publication on the issue, inexplicably, he never mentioned his histopathological discovery again. Despite several hypotheses, the reasons that led him to neglect (reject the structure which he so preeminently described have remained elusive.

  4. Sudden Death: An Uncommon Occurrence in Dementia with Lewy Bodies.

    Science.gov (United States)

    Molenaar, Joery P; Wilbers, Joyce; Aerts, Marjolein B; Leijten, Quinten H; van Dijk, Jan G; Esselink, Rianne A; Bloem, Bastiaan R

    2016-01-01

    We present a 75-year-old woman with dementia and parkinsonism who developed severe orthostatic hypotension and eventually died. Autopsy revealed extensive Lewy body formation in the midbrain, limbic system, intermediate spinal cord, and medulla oblongata. Furthermore, a vast amount of Lewy bodies was seen in the paravertebral sympathetic ganglia which likely explained the severe autonomic failure. We speculate that this autonomic failure caused sudden death through dysregulation of respiration or heart rhythm, reminiscent of sudden death in multiple system atrophy (MSA). Clinicians should be aware of this complication in patients presenting with parkinsonism and autonomic dysfunction, and that sudden death may occur in dementia with Lewy bodies (DLB) as it does in MSA.

  5. Radiation exposure of the public as a result of the present operations of Ranger Uranium Mines Pty Ltd

    Energy Technology Data Exchange (ETDEWEB)

    Koperski, J

    1986-04-01

    Ranger Uranium Mines monitors ambient levels of ionising radiation in accordance with the Code of Practice on Radiation Protection in the Mining and Milling of Radioactive Ores 1980. The radionuclides of interest are: U-238, Th-230, Ra-226, Pb-210, Po-210 and Rn-222 daughters (RnD). The aerial pathway appears to be the critical pathway for transfer of radioactive contaminants to the local population. The average annual effective dose equivalent rate to a member of the critical group from inhalation of long-lived radioactive dust is 0.22 +- 0.10 mSv/y, about 22 times below the limit of 5 mSv/y. No experimental evidence was found for any overall increase of exposure of the public due to consumption of bush food items collected in the vicinity of the Ranger site. The average exposure of the critical group member to RnD is likely to be 2.1 +- 3.1 mWLM/y, or 200 times below the annual limit of 0.4 WLM.

  6. Fugle og andre observationer på Lewis og Harris

    DEFF Research Database (Denmark)

    Provencal, Philippe

    2017-01-01

    En beskrivelse af observationer af især fugle men også nogle få pattedyr på øen Lewis and Harris i de Ydre Hebrider. Observationerne fandt sted fra den 19. til den 23- april 2017.......En beskrivelse af observationer af især fugle men også nogle få pattedyr på øen Lewis and Harris i de Ydre Hebrider. Observationerne fandt sted fra den 19. til den 23- april 2017....

  7. Lewis acid enhanced switching of the 1,1-dicyanodihydroazulene/vinylheptafulvene photo/thermoswitch

    DEFF Research Database (Denmark)

    Parker, Christian Richard; Tortzen, Christian Gregers; Broman, Søren Lindbæk

    2011-01-01

    Mild Lewis acids enhance the rate of the thermal conversion of vinylheptafulvene (VHF) to dihydroazulene (DHA). In the absence of light, stronger Lewis acids promote the otherwise photoinduced DHA to VHF conversion.......Mild Lewis acids enhance the rate of the thermal conversion of vinylheptafulvene (VHF) to dihydroazulene (DHA). In the absence of light, stronger Lewis acids promote the otherwise photoinduced DHA to VHF conversion....

  8. preparation of bicyclic lactones using lewis acids catalyzed ene

    African Journals Online (AJOL)

    Administrator

    The synthesis of the cis-fused bicyclic lactones relies extensively on the Lewis acid ... having an allylic hydrogen (an"ene") and a compound containing an electron .... observed that the lithium enolate obtained from 3-methyl-2(5H)- furanone ...

  9. Frustrated Lewis pairs-assisted reduction of carbonyl compounds

    Czech Academy of Sciences Publication Activity Database

    Marek, Aleš; Pedersen, M. H. F.

    2015-01-01

    Roč. 71, č. 6 (2015), s. 917-921 ISSN 0040-4020 Institutional support: RVO:61388963 Keywords : frustrated Lewis pairs * hydrogen activation * benzyl alcohol * tritium labeling * labeled compounds Subject RIV: CC - Organic Chemistry Impact factor: 2.645, year: 2015

  10. Q & A with Ed Tech Leaders: Interview with Brian Lewis

    Science.gov (United States)

    Shaughnessy, Michael F.; Fulgham, Susan M.

    2013-01-01

    Brian Lewis, International Society for Technology in Education (ISTE) chief executive officer, is an education advocate and leader specializing in management and governance, policy, corporate communications, branding, and marketing. He provides leadership to ISTE's Washington, DC, and Eugene, Oregon, offices and directs organizational…

  11. Daniel Day-Lewis - veri peab voolama / Kristiina Davidjants

    Index Scriptorium Estoniae

    Davidjants, Kristiina, 1974-

    2008-01-01

    Iiri-juudi näitleja Daniel Day-Lewis, kes võitis oma rolliga P.T. Andersoni filmis "Veri hakkab voolama" parima meespeaosatäitja Oscari. Tema põhjalikust tööst rollidega läbi tema filmiloomingu

  12. Who Needs Lewis Structures to Get VSEPR Geometries?

    Science.gov (United States)

    Lindmark, Alan F.

    2010-01-01

    Teaching the VSEPR (valence shell electron-pair repulsion) model can be a tedious process. Traditionally, Lewis structures are drawn and the number of "electron clouds" (groups) around the central atom are counted and related to the standard VSEPR table of possible geometries. A simpler method to deduce the VSEPR structure without first drawing…

  13. Bibliography of Lewis Research Center Technical Publications announced in 1991

    Science.gov (United States)

    1992-01-01

    This compilation of abstracts describes and indexes the technical reporting that resulted from the scientific engineering work performed and managed by the Lewis Research Center in 1991. All the publications were announced in the 1991 issues of STAR (Scientific and Technical Aerospace Reports) and/or IAA (International Aerospace Abstracts). Included are research reports, journal articles, conference presentations, patents and patent applications, and theses.

  14. Frustrated Lewis pairs-assisted reduction of carbonyl compounds

    DEFF Research Database (Denmark)

    Marek, Ales; Pedersen, Martin Holst Friborg

    2015-01-01

    An alternative and robust method for the reduction of carbonyl groups by frustrated Lewis pairs (FLPs) is reported in this paper. With its very mild reaction conditions, good to excellent yields, absolute regioselectivity and the non-metallic character of the reagent, it provides an excellent too...

  15. Reduced CSF CART in dementia with Lewy bodies

    DEFF Research Database (Denmark)

    Schultz, Kristofer; Wiehager, Sara; Nilsson, Karin

    2009-01-01

    Dementia with Lewy bodies (DLB) is the second most common form of neurodegenerative dementia after Alzheimer's disease (AD). The underlying neurobiological mechanism of DLB is not fully understood and no generally accepted biomarkers are yet available for the diagnosis of DLB. In a recent MRI study...

  16. Modified NASA-Lewis chemical equilibrium code for MHD applications

    Science.gov (United States)

    Sacks, R. A.; Geyer, H. K.; Grammel, S. J.; Doss, E. D.

    1979-01-01

    A substantially modified version of the NASA-Lewis Chemical Equilibrium Code was recently developed. The modifications were designed to extend the power and convenience of the Code as a tool for performing combustor analysis for MHD systems studies. The effect of the programming details is described from a user point of view.

  17. Fullerene–Carbene Lewis Acid–Base Adducts

    KAUST Repository

    Li, Huaping; Risko, Chad; Seo, Jung Hwa; Campbell, Casey; Wu, Guang; Brédas, Jean-Luc; Bazan, Guillermo C.

    2011-01-01

    The reaction between a bulky N-heterocylic carbene (NHC) and C60 leads to the formation of a thermally stable zwitterionic Lewis acid-base adduct that is connected via a C-C single bond. Low-energy absorption bands with weak oscillator strengths

  18. File list: DNS.Lng.10.AllAg.Carcinoma,_Lewis_Lung [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Lng.10.AllAg.Carcinoma,_Lewis_Lung mm9 DNase-seq Lung Carcinoma, Lewis Lung htt...p://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/DNS.Lng.10.AllAg.Carcinoma,_Lewis_Lung.bed ...

  19. File list: DNS.Lng.50.AllAg.Carcinoma,_Lewis_Lung [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Lng.50.AllAg.Carcinoma,_Lewis_Lung mm9 DNase-seq Lung Carcinoma, Lewis Lung htt...p://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/DNS.Lng.50.AllAg.Carcinoma,_Lewis_Lung.bed ...

  20. File list: Unc.Lng.20.AllAg.Carcinoma,_Lewis_Lung [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  1. File list: Oth.Lng.05.AllAg.Carcinoma,_Lewis_Lung [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  2. File list: His.Lng.05.AllAg.Carcinoma,_Lewis_Lung [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  3. File list: Pol.Lng.50.AllAg.Carcinoma,_Lewis_Lung [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  4. File list: Pol.Lng.05.AllAg.Carcinoma,_Lewis_Lung [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  5. File list: Pol.Lng.10.AllAg.Carcinoma,_Lewis_Lung [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  6. File list: DNS.Lng.20.AllAg.Carcinoma,_Lewis_Lung [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  7. Tribute to Erwin Felix Lewy-Bertaut; Hommage a Erwin Felix Lewy-Bertaut

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    Erwin Lewy (alias Felix Bertaut) was born in 1913 in Germany, he emigrated to France where he undertook graduate studies in chemistry. Then, he joined the powder central laboratory where he learnt how to use international tables for structure determination. His thesis work was the X-ray study of the statistical distribution of the size of iron grains. The method Bertaut developed is still a reference in powder granulometry. Bertaut was also interested in the nascent neutron diffraction method and he flew to the United-States to improve his knowledge on this topic. Felix Bertaut created the neutron diffraction laboratory in the atomic research center in Grenoble and later he headed the CNRS' crystallography laboratory till 1982. Felix Bertaut and his laboratories became internationally renowned in crystallography, neutron diffraction and magnetism. He favored the scientific cooperation between France and Germany that led to the creation of the Laue-Langevin Institute (ILL). The ILL became European and was a key partner for building the European Synchrotron Facility (ESRF) in Grenoble. Bertaut was elected as a full member of the French Academy of Sciences in 1979, he died in 2003. (A.C.)

  8. Private Water Districts

    Data.gov (United States)

    California Natural Resource Agency — Private Water District boundaries are areas where private contracts provide water to the district in California. This database is designed as a regions polygon...

  9. Lieutenant Chief Warden Districts

    Data.gov (United States)

    Vermont Center for Geographic Information — This dataset is a representation overlay of Lieutenant Chief Warden Districts (areas of responsibility). The Vermont Lieutenant Chief Warden Districts layer is part...

  10. District heating in Switzerland

    International Nuclear Information System (INIS)

    Herzog, F.

    1991-01-01

    District heating has been used in Switzerland for more than 50 years. Its share of the heat market is less than 3% today. An analysis of the use of district heating in various European countries shows that a high share of district heating in the heat market is always dependent on ideal conditions for its use. Market prospects and possible future developments in the use of district heating in Switzerland are described in this paper. The main Swiss producers and distributors of district heating are members of the Association of District Heating Producers and Distributors. This association supports the installation of district heating facilities where ecological, energetical and economic aspects indicate that district heating would be a good solution. (author) 2 tabs., 6 refs

  11. California Political Districts

    Data.gov (United States)

    California Natural Resource Agency — This is a series of district layers pertaining to California'spolitical districts, that are derived from the California State Senateand State Assembly information....

  12. State Water Districts

    Data.gov (United States)

    California Natural Resource Agency — State Water Project District boundaries are areas where state contracts provide water to the district in California. This database is designed as a regions polygon...

  13. National Register Historic Districts

    Data.gov (United States)

    Iowa State University GIS Support and Research Facility — The National Register Historic District layer is a shape file showing the boundaries of Historic Districts that are listed on the National Register of Historic Places.

  14. Zero Energy Districts

    Energy Technology Data Exchange (ETDEWEB)

    Polly, Benjamin J [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2018-05-04

    This presentation shows how NREL is approaching Zero Energy Districts, including key opportunities, design strategies, and master planning concepts. The presentation also covers URBANopt, an advanced analytical platform for district that is being developed by NREL.

  15. District nurse training

    OpenAIRE

    Elliott, Arnold; Freeling, Paul; Owen, John

    1980-01-01

    Training for district nursing is being reviewed. By 1981 district nurses will have a new administrative structure, a new curriculum, and a new examination. Training for nursing, like that for general practice, is to become mandatory. The history of the development of district nurse training is briefly described.

  16. District nursing in Dominica

    NARCIS (Netherlands)

    Kolkman, PME; Luteijn, AJ; Nasiiro, RS; Bruney, [No Value; Smith, RJA; Meyboom-de Jong, B

    1998-01-01

    District nurses constitute the basis of the primary health care services in Dominica. All encounters of three district nurses were registered using the international classification of primary care. Information on other aspects of district nursing was collected by participating observation and the

  17. Diagnostic pitfalls in a young Romanian ranger with an acute psychotic episode

    Directory of Open Access Journals (Sweden)

    Nagy EE

    2016-05-01

    Full Text Available Elöd Ernö Nagy,1,2 Attila Rácz,3 Edit Urbán,4 Gabriella Terhes,4 Timea Berki,5 Emöke Horváth,6 Anca M Georgescu,7 Iringó E Zaharia-Kézdi71Department of Pharmaceutical Biochemistry, University of Medicine and Pharmacy of Târgu-Mureş, 2Laboratory of Medical Analysis, Mures Clinical County Hospital, 3II. Psychiatry Clinic, Mures Clinical County Hospital, Târgu Mureş, Romania; 4Faculty of Medicine, Institute of Clinical Microbiology, University of Szeged, Szeged, 5Faculty of Medicine, Institute of Immunology and Biotechnology, University of Pécs, Pécs, Hungary; 6Department of Pathology, 7I. Clinic of Infectious Disease, University of Medicine and Pharmacy, Târgu Mureş, RomaniaAbstract: The identification and distinction of the pathological conditions underlying acute psychosis are often challenging. We present the case of a 35-year-old ranger who had no history of acute or chronic infectious disease or any previous neuropsychiatric symptoms. He arrived at the Psychiatry Clinic and was admitted as an emergency case, displaying bizarre behavior, hallucinations, paranoid ideation, and delusional faults. These symptoms had first appeared 7 days earlier. An objective examination revealed abnormalities of behavior, anxiety, visual hallucinations, choreiform, and tic-like facial movements. After the administration of neuroleptic and antidepressant treatment, he showed an initial improvement, but on day 10 entered into a severe catatonic state with signs of meningeal irritation and was transferred to the intensive care unit. An electroencephalogram showed diffuse irritative changes, raising the possibility of encephalitis. Taking into consideration the overt occupational risk, Borrelia antibody tests were prescribed and highly positive immunoglobulin (IgM and IgG titers were obtained from serum, along with IgG and antibody index positivity in cerebrospinal fluid. In parallel, anti-N-methyl-D-aspartate receptor antibodies and a whole

  18. Lewis basicity of relevant monoanions in a non-protogenic organic solvent using a zinc(ii) Schiff-base complex as a reference Lewis acid.

    Science.gov (United States)

    Oliveri, Ivan Pietro; Di Bella, Santo

    2017-09-12

    Anions are ubiquitous species playing a primary role in chemistry, whose reactivity is essentially dominated by their Lewis basicity. However, no Lewis basicity data, in terms of Gibbs energy, are reported in the literature. We report here the first Lewis basicity of relevant monoanions through the determination of binding constants for the formation of stable 1 : 1 adducts, using a Zn II Schiff-base complex, 1, as a reference Lewis acid. Binding constants for equilibrium reactions were achieved through a nonlinear regression analysis of the binding isotherms from spectrophotometric titration data. The Lewis acidic complex 1 is a proper reference species because it forms stable adducts with both neutral and charged Lewis bases, thus allowing ranking their Lewis basicity. Binding constants indicate generally a strong Lewis basicity for all involved anions, rivalling or exceeding that of the stronger neutral bases, such as primary amines or pyridine. The cyanide anion results to be the strongest Lewis base, while the nitrate is the weaker base within the present anion series. Moreover, even the weaker base anions behave as stronger bases than the most common non-protogenic coordinating solvents.

  19. Incorporating spectroscopic on-line monitoring as a method of detection for a Lewis cell setup

    Energy Technology Data Exchange (ETDEWEB)

    Heller, Forrest D.; Casella, Amanda J.; Lumetta, Gregg J.; Nash, Kenneth L.; Sinkov, Sergey I.; Bryan, Samuel A.

    2017-01-01

    A Lewis cell was designed and constructed for investigating solvent extraction systems by spectrophotometrically monitoring both the organic and aqueous phases in real time. This new Lewis cell was tested and shown to perform well compared to other previously reported Lewis cell designs. The advantage of the new design is that the spectroscopic measurement allows determination of not only metal ion concentrations, but also information regarding chemical speciation—information not available with previous Lewis cell designs. For convenience, the new Lewis cell design was dubbed COSMOFLEX (COntinuous Spectroscopic MOnitoring of Forrest’s Liquid-liquid EXtraction cell).

  20. A summary of Alaska's unique cruise ship program : wastewater, air emissions, and ocean rangers

    Energy Technology Data Exchange (ETDEWEB)

    Koch, D. [Alaska Dept. of Environmental Conservation, Juneau, AK (United States)

    2009-07-01

    Increased environmental awareness has led to concerns over the impacts of cruise ships on Alaska's marine environment. Federal legislation has been passed to ensure that large cruise ships no longer dump bilge water in areas within 3 nautical miles from the state's shoreline. The state has also been legislation to regulate sewage releases from both small and large vessels. The state requires registration, fees, and plans for emissions, and hazardous and solid wastes. As a result of the regulations, all large cruise ships discharging wastewater in Alaska had advanced wastewater treatment systems by 2003. The systems consist of solids separation, enhanced aerobic digestion, ultrafiltration, reverse osmosis, and ultraviolet disinfection systems. The quality of sewage dramatically improved in the region. Ocean rangers are now inspecting approximately 88 per cent of cruise ships visiting the Alaska region. Details of recent wastewater compliance actions were presented, as well as data on wastewater and waste emission limits. tabs., figs.

  1. Novel Tools in Determining the Physiological Demands and Nutritional Practices of Ontario FireRangers during Fire Deployments.

    Directory of Open Access Journals (Sweden)

    A H Robertson

    Full Text Available The seasonal profession of wildland fire fighting in Canada requires individuals to work in harsh environmental conditions that are physically demanding. The purpose of this study was to use novel technologies to evaluate the physiological demands and nutritional practices of Canadian FireRangers during fire deployments.Participants (n = 21 from a northern Ontario Fire Base volunteered for this study and data collection occurred during the 2014 fire season and included Initial Attack (IA, Project Fire (P, and Fire Base (B deployments. Deployment-specific energy demands and physiological responses were measured using heart-rate variability (HRV monitoring devices (Zephyr BioHarness3 units. Food consumption behaviour and nutrient quantity and quality were captured using audio-video food logs on iPod Touches and analyzed by NutriBase Pro 11 software.Insufficient kilocalories were consumed relative to expenditure for all deployment types. Average daily kilocalories consumed: IA: 3758 (80% consumption rate; P: 2945±888.8; B: 2433±570.8. Average daily kilocalorie expenditure: IA: 4538±106.3; P: 4012±1164.8; B: 2842±649.9. The Average Macronutrient Distribution Range (AMDR for protein was acceptable: 22-25% (across deployment types. Whereas the AMDR for fat and carbohydrates were high: 40-50%; and low: 27-37% respectively, across deployment types.This study is the first to use the described methodology to simultaneously evaluate energy expenditures and nutritional practices in an occupational setting. The results support the use of HRV monitoring and video-food capture, in occupational field settings, to assess job demands. FireRangers expended the most energy during IA, and the least during B deployments. These results indicate the need to develop strategies centered on maintaining physical fitness and improving food practices.

  2. Effect of unequal fuel and oxidizer Lewis numbers on flame dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Shamim, Tariq [Department of Mechanical Engineering, The University of Michigan-Dearborn, Dearborn, MI 48128-1491 (United States)

    2006-12-15

    The interaction of non-unity Lewis number (due to preferential diffusion and/or unequal rates of heat and mass transfer) with the coupled effect of radiation, chemistry and unsteadiness alters several characteristics of a flame. The present study numerically investigates this interaction with a particular emphasis on the effect of unequal and non-unity fuel and oxidizer Lewis numbers in a transient diffusion flame. The unsteadiness is simulated by considering the flame subjected to modulations in reactant concentration. Flames with different Lewis numbers (ranging from 0.5 to 2) and subjected to different modulating frequencies are considered. The results show that the coupled effect of Lewis number and unsteadiness strongly influences the flame dynamics. The impact is stronger at high modulating frequencies and strain rates, particularly for large values of Lewis numbers. Compared to the oxidizer side Lewis number, the fuel side Lewis number has greater influence on flame dynamics. (author)

  3. The Organization of Narrative Discourse in Lewy Body Spectrum Disorder

    Science.gov (United States)

    Ash, Sharon; McMillan, Corey; Gross, Rachel G.; Cook, Philip; Morgan, Brianna; Boller, Ashley; Dreyfuss, Michael; Siderowf, Andrew; Grossman, Murray

    2011-01-01

    Narrative discourse is an essential component of day-to-day communication, but little is known about narrative in Lewy Body spectrum disorder (LBSD), including Parkinson's disease (PD), Parkinson's disease with dementia (PDD), and dementia with Lewy bodies (DLB). We performed a detailed analysis of a semi-structured speech sample in 32 non-aphasic patients with LBSD, and we related their narrative impairments to gray matter (GM) atrophy using voxel-based morphometry. We found that patients with PDD and DLB have significant difficulty organizing their narrative speech. This was correlated with deficits on measures of executive functioning and speech fluency. Regression analyses associated this deficit with reduced cortical volume in inferior frontal and anterior cingulate regions. These findings are consistent with a model of narrative discourse that includes executive as well as language components and with an impairment of the organizational component of narrative discourse in patients with PDD and DLB. PMID:21689852

  4. Operational criteria for senile dementia of Lewy body type (SDLT).

    Science.gov (United States)

    McKeith, I G; Perry, R H; Fairbairn, A F; Jabeen, S; Perry, E K

    1992-11-01

    Recent reports have suggested that brain stem and cortical Lewy body formation may identify a neurodegenerative disorder in elderly demented individuals which accounts for up to 20% of cases of senile dementia coming to autopsy. Retrospective analysis of case notes of 21 autopsy patients with neuropathologically proven senile dementia of Lewy body type (SDLT) and 37 cases with neuropathologically proven Alzheimer's disease (AD) identified a characteristic clinical syndrome in SDLT. Fluctuating cognitive impairment; psychotic features including visual and auditory hallucinations, and paranoid delusions; depressive symptoms; falling and unexplained losses of consciousness were all seen significantly more often than in AD. Over half of the SDLT patients in this series who were given neuroleptics in standard dose showed acute and often irreversible adverse reactions indicative of a neuroleptic sensitivity syndrome. The survival time of drug treated patients was reduced by 50%. Operational criteria to aid in the clinical distinction between SDLT and AD patients are proposed and hypotheses regarding possible aetiology and treatment discussed.

  5. Imidazolinium and amidinium salts as Lewis acid organocatalysts

    Directory of Open Access Journals (Sweden)

    Oksana Sereda

    2012-10-01

    Full Text Available The application of imidazolinium and amidinium salts as soft Lewis acid organocatalysts is described. These salts were suitable catalysts for the activation of unsaturated thioesters in a Diels–Alder reaction and in the ring opening of thiiranes and epoxides. The products were isolated in good yields. The mild catalysts did not cause desulfurization of the products containing a thiol or thiocarbonyl group.

  6. Improved Lignin Polyurethane Properties with Lewis Acid Treatment

    OpenAIRE

    Chung, Hoyong; Washburn, Newell R.

    2012-01-01

    Chemical modification strategies to improve the mechanical properties of lignin-based polyurethanes are presented. We hypothesized that treatment of lignin with Lewis acids would increase the concentration of hydroxyl groups available to react with diisocyanate monomers. Under the conditions used, hydrogen bromide-catalyzed modification resulted in a 28% increase in hydroxyl group content. Associated increases in hydrophilicity of solvent-cast thin films were also recorded as evidenced by ...

  7. Bibliography of Lewis Research Center technical publications announced in 1990

    Science.gov (United States)

    1991-01-01

    This compilation of abstracts describes and indexes the technical reporting that resulted from the scientific and engineering work performed and managed by the Lewis Research Center in 1990. All the publications were announced in the 1990 issues of STAR (Scientific and Technical Aerospace Reports) and/or IAA (International Aerospace Abstracts). Included are research reports, journal articles, conference presentations, patents and patent applications, and theses.

  8. Bibliography of Lewis Research Center technical publications announced in 1992

    Science.gov (United States)

    1993-01-01

    This compilation of abstracts describes and indexes the technical reporting that resulted from the scientific and engineering work performed and managed by the Lewis Research Center in 1992. All the publications were announced in the 1992 issues of STAR (Scientific and Technical Aerospace Reports) and/or IAA (International Aerospace Abstracts). Included are research reports, journal articles, conference presentations, patents and patent applications, and theses.

  9. Bibliography of Lewis Research Center technical publications announced in 1993

    Science.gov (United States)

    1994-01-01

    This compilation of abstracts describes and indexes the technical reporting that resulted from the scientific and engineering work performed and managed by the Lewis Research Center in 1993. All the publications were announced in the 1993 issues of STAR (Scientific and Technical Aerospace Reports) and/or IAA (International Aerospace Abstracts). Included are research reports, journal articles, conference presentations, patents and patent applications, and theses.

  10. Bibliography of Lewis Research Center technical publications announced in 1989

    Science.gov (United States)

    1990-01-01

    This compilation of abstracts describes and indexes the technical reporting that resulted from the scientific and engineering work performed and managed by the Lewis Research Center in 1989. All the publications were announced in the 1989 issues of STAR (Scientific and Technical Aerospace Reports) and/or IAA (International Aerospace Abstracts). Included are research reports, journal articles, conference presentations, patents and patent applications, and theses.

  11. Lewis' Educational and Research Collaborative Intership Program Grant Closeout Report

    Science.gov (United States)

    2003-01-01

    The Lewis' Educational and Research Collaborative Internship Program (LERCIP) is a collaborative undertaking by the Office of Educational Programs at NASA Glenn Research Center at Lewis Field (formerly NASA Lewis Research Center) and the Ohio Aerospace Institute. This program provides 10-week internships and 10 or 12-week fellowships for undergraduate/graduate students and secondary school teachers. Approximately 130 interns are selected to participate in this program each year and begin arriving the second week in May. The internships provide students with introductory professional experiences to complement their academic programs. The interns are given assignments on research and development projects under the personal guidance of NASA professional staff members. Each intern is assigned a NASA mentor who facilitates a research assignment. In addition to the research assignment, the summer program includes a strong educational component that enhances the professional stature of the participants. The educational activities include a research symposium and a variety of workshops, lectures and short courses. An important aspect of the program is that it includes students with diverse social, cultural and economic backgrounds.

  12. Developing an approach for teaching and learning about Lewis structures

    Science.gov (United States)

    Kaufmann, Ilana; Hamza, Karim M.; Rundgren, Carl-Johan; Eriksson, Lars

    2017-08-01

    This study explores first-year university students' reasoning as they learn to draw Lewis structures. We also present a theoretical account of the formal procedure commonly taught for drawing these structures. Students' discussions during problem-solving activities were video recorded and detailed analyses of the discussions were made through the use of practical epistemology analysis (PEA). Our results show that the formal procedure was central for drawing Lewis structures, but its use varied depending on situational aspects. Commonly, the use of individual steps of the formal procedure was contingent on experiences of chemical structures, and other information such as the characteristics of the problem given. The analysis revealed a number of patterns in how students constructed, checked and modified the structure in relation to the formal procedure and the situational aspects. We suggest that explicitly teaching the formal procedure as a process of constructing, checking and modifying might be helpful for students learning to draw Lewis structures. By doing so, the students may learn to check the accuracy of the generated structure not only in relation to the octet rule and formal charge, but also to other experiences that are not explicitly included in the formal procedure.

  13. Development of Fluorous Lewis Acid-Catalyzed Reactions

    Directory of Open Access Journals (Sweden)

    Joji Nishikido

    2006-08-01

    Full Text Available Organic synthetic methodology in the 21st century aims to conform to the principles of green sustainable chemistry (GSC and we may expect that in the future, the realization of GSC will be an important objective for chemical industries. An important aim of synthetic organic chemistry is to implement waste-free and environmentally-benign industrial processes using Lewis acids as versatile as aluminum choride. A key technological objective of our work in this area has been to achieve a “catalyst recycling system that utilizes the high activity and structural features of fluorous Lewis acid catalysts”. Thus, we have developed a series of novel fluorous Lewis acid catalysts, namely the ytterbium(III, scandium(III, tin(IV or hafnium(IV bis(perfluoroalkanesulfonylamides or tris(perfluoro- alkanesulfonylmethides. Our catalysts are recyclable and effective for acylations of alcohols and aromatics, Baeyer-Villiger reactions, direct esterifications and transesterifications in a fluorous biphasic system (FBS, in supercritical carbon dioxide and on fluorous silica gel supports.

  14. Fullerene–Carbene Lewis Acid–Base Adducts

    KAUST Repository

    Li, Huaping

    2011-08-17

    The reaction between a bulky N-heterocylic carbene (NHC) and C60 leads to the formation of a thermally stable zwitterionic Lewis acid-base adduct that is connected via a C-C single bond. Low-energy absorption bands with weak oscillator strengths similar to those of n-doped fullerenes were observed for the product, consistent with a net transfer of electron density to the C60 core. Corroborating information was obtained using UV photoelectron spectroscopy, which revealed that the adduct has an ionization potential ∼1.5 eV lower than that of C60. Density functional theory calculations showed that the C-C bond is polarized, with a total charge of +0.84e located on the NHC framework and -0.84e delocalized on the C 60 cage. The combination of reactivity, characterization, and theoretical studies demonstrates that fullerenes can behave as Lewis acids that react with C-based Lewis bases and that the overall process describes n-doping via C-C bond formation. © 2011 American Chemical Society.

  15. Lewis acid catalyzed transformations of Z-ligustilide

    Energy Technology Data Exchange (ETDEWEB)

    Rios, Maria Yolanda [Universidad Autonoma del Estado de Morelos, Cuernavaca, Morelos (Mexico); Delgado, Guillermo [Universidad Nacional Autonoma de Mexico, Mexico, D.F. (Mexico)

    1999-08-01

    Some Lewis acid mediated reactions of Z-ligustilide (1), a bioactive constituent of the medicinal species Ligusticum porteri, were investigated. These reactions provided varying mixtures of Z-butylidenephthalide (7), E-butylidenephthalide (8), n-butyphthalide (13), and novel linear dimeric phthalides (9-12) as the main products. The formation of the dimers occurred in low yields and with regio and situ-selectivity. Initial competitive O- and C- complexation of the Lewis acid with Z-ligustilide promoted the formation of the dimers occurred in low yields and with regio and situ- selectivity. Initial competitive O- and C- complexation of the Lewis acid with Z-ligustilide promoted the formation of carbocations at C(8), C(6) and C(7), which were stabilized by the addition of the C(6')-C(7') olefin of a second unit of the starting material, to provide cations at C(6') and C(7'). Subsequent isomerizations and elimination of the catalyst afforded the dimeric products 9-12. The yields and structure of the products are quite dependent on variations of the reaction conditions and the catalyst employed. [Spanish] Se investigaron algunas reacciones de Z-ligustilidas (1), un constituyente bioactivo de la planta medicinal Ligusticum porteri, catalizadas por acidos de Lewis. Estas reacciones produjeron mezclas variables de Z-butilidenftalida (7), E-butilidenftalida (8), n-butilftalida (13), y ftalidos dimetricos lineales novedosos (9-12) como productos principales. La formacion de los dimeros procedio en rendimientos bajos y con regio- y situ-selectividad. La O- y C- complejacion competitiva inicial del acido de Lewis con Z-lingustilida promueve la formacion de cationes en C(8), C(6) y C(7), los cuales son estabilizados por la adicion de la olefina C(6')-C(7') de una segunda unidad de la materia prima para generar los cationes en C(6')-C(7'). Isomerizaciones subsecuentes y la eliminacion del catalizador conducen a los productos dimericos 9

  16. District heating in Italy

    International Nuclear Information System (INIS)

    Sacchi, E.

    1998-01-01

    The legislative act establishing the electric monopoly virtually shut out the district heating associated with electricity cogeneration, while other laws, issued to counteract the effects of oil shocks, allowed municipal utilities to do so. Thus, district heating has experienced some development, though well below its possibilities. The article analyses the reasons for this lagging, reports district heating data and projects its forecasts against the Kyoto Protocol objectives [it

  17. Gilbert Newton Lewis: his influence on physical-organic chemists at Berkeley

    International Nuclear Information System (INIS)

    Calvin, M.

    1982-03-01

    A review is presented of the historical contributions of Gilbert N. Lewis to science and a discussion of the influence of Lewis on the research of the members of the physical-organic staff at Berkeley, including Melvin Calvin, during the twenties, thirties and forties. Some specific examples are discussed. Also, the effect of Lewis, his science and administrative concepts in the creation of excellence in a department of chemistry are reviewed

  18. Gilbert Newton Lewis: his influence on physical-organic chemists at Berkeley

    Energy Technology Data Exchange (ETDEWEB)

    Calvin, M.

    1982-03-01

    A review is presented of the historical contributions of Gilbert N. Lewis to science and a discussion of the influence of Lewis on the research of the members of the physical-organic staff at Berkeley, including Melvin Calvin, during the twenties, thirties and forties. Some specific examples are discussed. Also, the effect of Lewis, his science and administrative concepts in the creation of excellence in a department of chemistry are reviewed.

  19. Nankana West District of Ghana

    African Journals Online (AJOL)

    Agribotix GCS 077

    Local governments in Ghana play very important roles with actors in the ... Metropolitan, Municipal and District Chief Executives (MMDCEs), the .... District Budget Officer, District Finance Officer, Presiding Member, members of the Works Sub-.

  20. NASA Lewis and Ohio Company Hit Hole in One

    Science.gov (United States)

    1998-01-01

    Ben Hogan Company's Golf Ball Division, which is based in Elyria, Ohio, had developed concepts and prototypes for new golf balls but was unable to determine exact performance characteristics. Specifically, the company's R&D department wanted to measure the spin rates of experimental golf balls. After the Golf Ball Division requested assistance, researchers and technicians from the NASA Lewis Research Center went to Elyria and conducted several days worth of tests. Ben Hogan is using the test results to improve the spin characteristics of a new ball it plans to introduce to the market.

  1. Feminine Hypostases in Epic Fantasy: Tolkien, Lewis, Rowling

    Directory of Open Access Journals (Sweden)

    Măcineanu Laura

    2015-12-01

    Full Text Available The paper identifies the types of female figures present in the works of three well-known fantasy writers, J.R.R. Tolkien, C.S. Lewis and J.K. Rowling, discussing the ways in which these characters are presented, their relationship with other characters, and their role in the economy of the novel, which is more important than may appear from a first reading. It also tries to explain the reasons that prompted the above-mentioned authors to choose these female hypostases.

  2. Telecommuting (Work-At-Home) at NASA Lewis Research Center

    Science.gov (United States)

    Srinidhi, Saragur M.

    1994-01-01

    This report presents a study in evaluating the viability of providing a work-at-home (telecommuting) program for Lewis Research Center's corporate employees using Integrated Services Digital Network (ISDN). Case studies have been presented for a range of applications from casual data access to interactive access. The network performance of telemedia applications were studied against future requirements for such level of remote connectivity. Many of the popular ISDN devices were characterized for network and service functionality. A set of recommendations to develop a telecommuting policy have been proposed.

  3. NASA Lewis advanced IPV nickel-hydrogen technology

    Science.gov (United States)

    Smithrick, John J.; Britton, Doris L.

    1993-01-01

    Individual pressure vessel (IPV) nickel-hydrogen technology was advanced at NASA Lewis and under Lewis contracts. Some of the advancements are as follows: to use 26 percent potassium hydroxide electrolyte to improve cycle life and performance, to modify the state of the art cell design to eliminate identified failure modes and further improve cycle life, and to develop a lightweight nickel electrode to reduce battery mass, hence reduce launch and/or increase satellite payload. A breakthrough in the LEO cycle life of individual pressure vessel nickel-hydrogen battery cells was reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 accelerated LEO cycles at 80 percent DOD compared to 3,500 cycles for cells containing 31 percent KOH. Results of the boiler plate cell tests have been validated at NWSC, Crane, Indiana. Forty-eight ampere-hour flight cells containing 26 and 31 percent KOH have undergone real time LEO cycle life testing at an 80 percent DOD, 10 C. The three cells containing 26 percent KOH failed on the average at cycle 19,500. The three cells containing 31 percent KOH failed on the average at cycle 6,400. Validation testing of NASA Lewis 125 Ah advanced design IPV nickel-hydrogen flight cells is also being conducted at NWSC, Crane, Indiana under a NASA Lewis contract. This consists of characterization, storage, and cycle life testing. There was no capacity degradation after 52 days of storage with the cells in the discharged state, on open circuit, 0 C, and a hydrogen pressure of 14.5 psia. The catalyzed wall wick cells have been cycled for over 22,694 cycles with no cell failures in the continuing test. All three of the non-catalyzed wall wick cells failed (cycles 9,588; 13,900; and 20,575). Cycle life test results of the Fibrex nickel electrode has demonstrated the feasibility of an improved nickel electrode giving a higher specific energy nickel-hydrogen cell. A nickel-hydrogen boiler plate cell using an 80

  4. Assessment of the meteorological data and atmospheric dispersion estimates in the Ranger 1 Uranium Mining Environmental Impact Statement

    International Nuclear Information System (INIS)

    Clark, G.H.

    1977-03-01

    Wind records from Jabiru, Northern Territory, Australia have been re-analysed to give atmospheric dispersion estimates of sulphur dioxide and radioactive contaminants associated with a proposed uranium mining and milling operation. Revisions in the plume rise equations have led to lower annual average sulphur dioxide air concentrations than those presented in the Ranger 1 Uranium Mining Environmental Impact Statement. Likewise, the short term peak air concentrations of sulphur dioxide were all within the United States Environment Protection Agency air quality standards. Even though the radon gas inventory was revised upwards, predicted concentrations were only slightly higher than those in the RUMEIS. An attempt was made at a first estimate of the uranium dust source term caused by wind suspension from stockpiled ore and waste rock. In a preliminary analysis using a 'surface depletion' model, it was estimated that uranium dust air concentrations would be decreased by about an order of magnitude when dry deposition was included in the atmospheric dispersion model. Integrating over all sources, radionuclides and meteorological conditions, the annual radiation dose to members of the public in the Regional Centre is estimated to be a maximum of 5 per cent of the recommended annual limits. (author)

  5. FPGA Implementation of an Amplitude-Modulated Continuous-Wave Ultrasonic Ranger Using Restructured Phase-Locking Scheme

    Directory of Open Access Journals (Sweden)

    P. Sumathi

    2010-01-01

    Full Text Available An accurate ultrasonic range finder employing Sliding Discrete Fourier Transform (SDFT based restructured phase-locked loop (RPLL, which is an improved version of the recently proposed integrated phase-locking scheme (IPLL, has been expounded. This range finder principally utilizes amplitude-modulated ultrasonic waves assisted by an infrared (IR pilot signal. The phase shift between the envelope of the reference IR pilot signal and that of the received ultrasonic signal is proportional to the range. The extracted envelopes are filtered by SDFT without introducing any additional phase shift. A new RPLL is described in which the phase error is driven to zero using the quadrature signal derived from the SDFT. Further, the quadrature signal is reinforced by another cosine signal derived from a lookup table (LUT. The pulse frequency of the numerically controlled oscillator (NCO is extremely accurate, enabling fine tuning of the SDFT and RPLL also improves the lock time for the 50 Hz input signal to 0.04 s. The percentage phase error for the range 0.6 m to 6 m is about 0.2%. The VHDL codes generated for the various signal processing steps were downloaded into a Cyclone FPGA chip around which the ultrasonic ranger had been built.

  6. Lewis base activation of Lewis acids: catalytic, enantioselective addition of glycolate-derived silyl ketene acetals to aldehydes.

    Science.gov (United States)

    Denmark, Scott E; Chung, Won-Jin

    2008-06-20

    A catalytic system involving silicon tetrachloride and a chiral, Lewis basic bisphosphoramide catalyst is effective for the addition of glycolate-derived silyl ketene acetals to aldehydes. It was found that the sense of diastereoselectivity could be modulated by changing the size of the substituents on the silyl ketene acetals. In general, the trimethylsilyl ketene acetals derived from methyl glycolates with a large protecting group on the alpha-oxygen provide enantiomerically enriched alpha,beta-dihydroxy esters with high syn-diastereoselectivity, whereas the tert-butyldimethylsilyl ketene acetals derived from bulky esters of alpha-methoxyacetic acid provide enantiomerically enriched alpha,beta-dihydroxy esters with high anti-diastereoselecitvity.

  7. Molecular Imaging and Updated Diagnostic Criteria in Lewy Body Dementias.

    Science.gov (United States)

    Bohnen, Nicolaas I; Müller, Martijn L T M; Frey, Kirk A

    2017-08-14

    The aims of the study were to review recent advances in molecular imaging in the Lewy body dementias (LBD) and determine if these may support the clinical but contested temporal profile distinction between Parkinson disease (PD) with dementia (PDD) versus dementia with Lewy bodies (DLB). There do not appear to be major regional cerebral metabolic or neurotransmitter distinctions between PDD and DLB. However, recent studies highlight the relative discriminating roles of Alzheimer proteinopathies. PDD patients have lower cortical β-amyloid deposition than DLB. Preliminary tau PET studies suggest a gradient of increasing tau binding from cognitively normal PD (absent to lowest) to cognitively impaired PD (low) to DLB (intermediate) to Alzheimer disease (AD; highest). However, tau binding in DLB, including the medial temporal lobe, is substantially lower than in AD. Alzheimer-type proteinopathies appear to be more common in DLB compared to PDD with relative but no absolute differences. Given the spectrum of overlapping pathologies, future α-synuclein ligands are expected to have the best potential to distinguish the LBD from pure AD.

  8. Lewis Acid Assisted Nitrate Reduction with Biomimetic Molybdenum Oxotransferase Complex.

    Science.gov (United States)

    Elrod, Lee Taylor; Kim, Eunsuk

    2018-03-05

    The reduction of nitrate (NO 3 - ) to nitrite (NO 2 - ) is of significant biological and environmental importance. While Mo IV (O) and Mo VI (O) 2 complexes that mimic the active site structure of nitrate reducing enzymes are prevalent, few of these model complexes can reduce nitrate to nitrite through oxygen atom transfer (OAT) chemistry. We present a novel strategy to induce nitrate reduction chemistry of a previously known catalyst Mo IV (O)(SN) 2 (2), where SN = bis(4- tert-butylphenyl)-2-pyridylmethanethiolate, that is otherwise incapable of achieving OAT with nitrate. Addition of nitrate with the Lewis acid Sc(OTf) 3 (OTf = trifluoromethanesulfonate) to 2 results in an immediate and clean conversion of 2 to Mo VI (O) 2 (SN) 2 (1). The Lewis acid additive further reacts with the OAT product, nitrite, to form N 2 O and O 2 . This work highlights the ability of Sc 3+ additives to expand the reactivity scope of an existing Mo IV (O) complex together with which Sc 3+ can convert nitrate to stable gaseous molecules.

  9. Impairments of speech fluency in Lewy body spectrum disorder.

    Science.gov (United States)

    Ash, Sharon; McMillan, Corey; Gross, Rachel G; Cook, Philip; Gunawardena, Delani; Morgan, Brianna; Boller, Ashley; Siderowf, Andrew; Grossman, Murray

    2012-03-01

    Few studies have examined connected speech in demented and non-demented patients with Parkinson's disease (PD). We assessed the speech production of 35 patients with Lewy body spectrum disorder (LBSD), including non-demented PD patients, patients with PD dementia (PDD), and patients with dementia with Lewy bodies (DLB), in a semi-structured narrative speech sample in order to characterize impairments of speech fluency and to determine the factors contributing to reduced speech fluency in these patients. Both demented and non-demented PD patients exhibited reduced speech fluency, characterized by reduced overall speech rate and long pauses between sentences. Reduced speech rate in LBSD correlated with measures of between-utterance pauses, executive functioning, and grammatical comprehension. Regression analyses related non-fluent speech, grammatical difficulty, and executive difficulty to atrophy in frontal brain regions. These findings indicate that multiple factors contribute to slowed speech in LBSD, and this is mediated in part by disease in frontal brain regions. Copyright © 2011 Elsevier Inc. All rights reserved.

  10. Solid Waste Management Districts

    Data.gov (United States)

    Vermont Center for Geographic Information — The Solid waste management districts layer is part of a dataset that contains administrative boundaries for Vermont's Agency of Natural Resources. This dataset...

  11. District nursing is vital.

    Science.gov (United States)

    Bliss, Julie

    2016-08-03

    Queen's Nursing Institute chief executive Crystal Oldman has welcomed the RCN congress resolution urging RCN council to lobby for all district nurses to have a specialist practice qualification. This provides the ideal route for future talent and must be supported.

  12. Floodplain District Permit

    Data.gov (United States)

    Montgomery County of Maryland — The purpose of a Floodplain District Permit (FPDP) is to control floodplain development in order to protect persons and property from danger and destruction and to...

  13. 115th Congressional Districts

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This layer depicts the 115th Congressional Districts for the United States, with attributes listing the elected officials for the 115th Congress. Elected to a...

  14. Allegheny County Council Districts

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — This dataset portrays the boundaries of the County Council Districts in Allegheny County. The dataset is based on municipal boundaries and City of Pittsburgh ward...

  15. ACT250 Districts

    Data.gov (United States)

    Vermont Center for Geographic Information — The ACT 250 Districts layer is part of a larger dataset that contains administrative boundaries for Vermont's Agency of Natural Resources. The dataset includes...

  16. NM Property Tax Districts

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This layer represents boundaries for New Mexico tax district "OUT" categories and incorporated/municipal "IN" categories as identified on the "Certificate of Tax...

  17. NM School District Boundaries

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The dataset represents the boundaries of all public school districts in the state of New Mexico. The source for the data layer is the New Mexico Public Education...

  18. Groundwater Managment Districts

    Data.gov (United States)

    Kansas Data Access and Support Center — This dataset outlines the location of the five Groundwater Management Districts in Kansas. GMDs are locally formed and elected boards for regional groundwater...

  19. Specific acid catalysis and Lewis acid catalysis of Diels–Alder reactions in aqueous media

    NARCIS (Netherlands)

    Mubofu, Egid B.; Engberts, Jan B.F.N.

    2004-01-01

    A comparative study of specific acid catalysis and Lewis acid catalysis of Diels–Alder reactions between dienophiles (1, 4 and 6) and cyclopentadiene (2) in water and mixed aqueous media is reported. The reactions were performed in water with copper(II) nitrate as the Lewis acid catalyst whereas

  20. An Integrated Perspective of Humanism and Supernaturalism for Education: C. S. Lewis's Version of Education

    Science.gov (United States)

    Lee, Seung Chun

    2013-01-01

    This paper explores some theoretical reflections on the connection between C. S. Lewis's thoughts on the purpose and process of education and his understanding of supernatural human nature which has been relatively little explored. An introduction about Lewis's career as a college teacher blends into the background of this paper. It is followed by…

  1. Nest-site selection and nest survival of Lewis's woodpecker in aspen riparian woodlands

    Science.gov (United States)

    Karen R. Newlon; Victoria A. Saab

    2011-01-01

    Riparian woodlands of aspen (Populus tremuloides) provide valuable breeding habitat for several cavity-nesting birds. Although anecdotal information for this habitat is available for Lewis's Woodpecker (Melanerpes lewis), no study has previously examined the importance of aspen woodlands to this species' breeding biology. From 2002 to 2004, we monitored 76...

  2. LewiSpace: An Exploratory Study with a Machine Learning Model in an Educational Game

    Science.gov (United States)

    Ghali, Ramla; Ouellet, Sébastien; Frasson, Claude

    2016-01-01

    The use of educational games as a tool for providing learners with a playful and educational aspect is widespread. In this paper, we present an educational game that we developed to teach a chemistry lesson, namely drawing a Lewis diagram. Our game is a 3D environment known as LewiSpace and aims at balancing between playful and educational…

  3. Catalytic Conversion of Glucose into 5-Hydroxymethylfurfural by Hf(OTf4 Lewis Acid in Water

    Directory of Open Access Journals (Sweden)

    Junjie Li

    2015-12-01

    Full Text Available A series of Lewis acidic metal salts were used for glucose dehydration to 5-hydroymethylfurfural (HMF in water. Effect of valence state, ionic radii of Lewis acidic cation, and the type of anions on the catalytic performance have been studied systematically. The experimental results showed that the valence state played an important role in determining catalytic activity and selectivity. It was found that a higher glucose conversion rate and HMF selectivity could be obtained over high valent Lewis acid salts, where the ionic radii of these Lewis acidic metal salts are usually relatively small. Analysis on the effect of the anions of Lewis acid salts on the catalytic activity and the selectivity suggested that a higher glucose conversion and HMF selectivity could be readily obtained with Cl−. Furthermore, the recyclability of high valence state Lewis acid salt was also studied, however, inferior catalytic performance was observed. The deactivation mechanism was speculated to be the fact that high valence state Lewis acid salt was comparatively easier to undergo hydrolysis to yield complicated metal aqua ions with less catalytic activity. The Lewis acidic activity could be recovered by introducing a stoichiometric amount of hydrochloric acid (HCl to the catalytic before the reaction.

  4. Lewis acid catalysis of a Diels-Alder reaction in water

    NARCIS (Netherlands)

    Otto, S; Bertoncin, F; Engberts, JBFN

    1996-01-01

    Here we report the first detailed study of a Diels-Alder (DA) reaction that is catalyzed by Lewis acids in water. The effect of Co2+, Ni2+, Cu2+ and Zn2+ ions as Lewis acid catalysts on the rate and endo-exo selectivity of the DA reaction between the bidentate dienophiles

  5. Lewis acid-catalyzed depolymerization of soda lignin in supercritical ethanol/water mixtures

    NARCIS (Netherlands)

    Güvenatam, Burcu; Heeres, Erik H.J.; Pidko, Evgeny A.; Hensen, Emiel J M

    2016-01-01

    The depolymerization of lignin model compounds and soda lignin by super Lewis acidic metal triflates has been investigated in a mixture of ethanol and water at 400 °C. The strong Lewis acids convert representative model compounds for the structure-forming linkages in lignin, namely α-O-4, 5-O-4

  6. Specific acid catalysis and Lewis acid catalysis of Diels-Alder reactions in aqueous media

    NARCIS (Netherlands)

    Mubofu, E.B.; Engberts, J.B.F.N.

    A comparative study of specific acid catalysis and Lewis acid catalysis of Diells-Alder reactions between dienophiles (1, 4 and 6) and cyclopentadiene (2) in water and mixed aqueous media is reported. The reactions were performed in water with copper(II) nitrate as the Lewis acid catalyst whereas

  7. Oral Interpretation of C.S. Lewis'"Narnia Tales": A Refracting of "Pictures."

    Science.gov (United States)

    Keefe, Carolyn

    "The Chronicles of Narnia" are a series of seven fairy tales written by C.S. Lewis that have become popular with both children and adults. Lewis points to five aspects of the fairy tale form that made the form suitable for expressing the images he saw. The aspects are: (1) no love interest; (2) no close psychology; (3) severe restraints…

  8. Reduced frequency of blood group Lewis a-b- in female Type 1 diabetes patients

    DEFF Research Database (Denmark)

    Kharagjitsingh, A.V.; Prinsen, K.; Lemkes, H.H.

    2008-01-01

    AIMS: To examine a disputed association between the Lewis(a(-)b(-)) phenotype and Type 1 diabetes (T1D). METHODS: Lewis red blood cell phenotyping was performed for 97 T1D White patients and 100 control subjects using monoclonal antibodies. Two historical cohorts were also included as a control...

  9. Streptococcal cell wall-induced arthritis and adjuvant arthritis in F344----Lewis and in Lewis----F344 bone marrow chimeras

    International Nuclear Information System (INIS)

    van Bruggen, M.C.; van den Broek, M.F.; van den Berg, W.B.

    1991-01-01

    Streptococcal cell wall (SCW)-induced arthritis and adjuvant arthritis (AA) are rat models for chronic, erosive polyarthritis. Both models can be induced in susceptible Lewis rats, whereas F344 rats are resistant. In AA as well as in SCW arthritis, antigen-specific T lymphocytes have been demonstrated to be crucial for chronic disease. In this communication the authors describe their studies to probe the cellular mechanism responsible for the difference in susceptibility of Lewis and F344, using bone marrow chimeras. By transplanting bone marrow cells from F344 into lethally irradiated Lewis recipients, Lewis rats were rendered resistant to SCW arthritis induction. F344 rats reconstituted with Lewis bone marrow, i.e., Lewis----F344 chimeras, develop an arthritis upon SCW injection. For AA comparable results were obtained. These data suggest that both resistance and susceptibility to bacterium-induced chronic arthritis are mediated by hemopoietic/immune cells and that the recipiental environment does not influence the susceptibility to chronic joint inflammation

  10. Elucidating the Key Role of a Lewis Base Solvent in the Formation of Perovskite Films Fabricated from the Lewis Adduct Approach.

    Science.gov (United States)

    Cao, Xiaobing; Zhi, Lili; Li, Yahui; Fang, Fei; Cui, Xian; Yao, Youwei; Ci, Lijie; Ding, Kongxian; Wei, Jinquan

    2017-09-27

    High-quality perovskite films can be fabricated from Lewis acid-base adducts through molecule exchange. Substantial work is needed to fully understand the formation mechanism of the perovskite films, which helps to further improve their quality. Here, we study the formation of CH 3 NH 3 PbI 3 perovskite films by introducing some dimethylacetamide into the PbI 2 /N,N-dimethylformamide solution. We reveal that there are three key processes during the formation of perovskite films through the Lewis acid-base adduct approach: molecule intercalation of solvent into the PbI 2 lattice, molecule exchange between the solvent and CH 3 NH 3 I, and dissolution-recrystallization of the perovskite grains during annealing. The Lewis base solvents play multiple functions in the above processes. The properties of the solvent, including Lewis basicity and boiling point, play key roles in forming smooth perovskite films with large grains. We also provide some rules for choosing Lewis base additives to prepare high-quality perovskite films through the Lewis adduct approach.

  11. Exercise for Individuals with Lewy Body Dementia: A Systematic Review.

    Directory of Open Access Journals (Sweden)

    Michael Inskip

    Full Text Available Individuals with Lewy body Dementia (LBD, which encompasses both Parkinson disease dementia (PDD and Dementia with Lewy Bodies (DLB experience functional decline through Parkinsonism and sedentariness exacerbated by motor, psychiatric and cognitive symptoms. Exercise may improve functional outcomes in Parkinson's disease (PD, and Alzheimer's disease (AD. However, the multi-domain nature of the LBD cluster of symptoms (physical, cognitive, psychiatric, autonomic results in vulnerable individuals often being excluded from exercise studies evaluating physical function in PD or cognitive function in dementia to avoid confounding results. This review evaluated existing literature reporting the effects of exercise interventions or physical activity (PA exposure on cluster symptoms in LBD.A high-sensitivity search was executed across 19 databases. Full-length articles of any language and quality, published or unpublished, that analysed effects of isolated exercise/physical activity on indicative Dementia with Lewy Bodies or PD-dementia cohorts were evaluated for outcomes inclusive of physical, cognitive, psychiatric, physiological and quality of life measures. The protocol for this review (Reg. #: CRD42015019002 is accessible at http://www.crd.york.ac.uk/PROSPERO/.111,485 articles were initially retrieved; 288 full articles were reviewed and 89.6% subsequently deemed ineligible due to exclusion of participants with co-existence of dementia and Parkinsonism. Five studies (1 uncontrolled trial, 1 randomized controlled trial and 3 case reports evaluating 16 participants were included. Interventions were diverse and outcome homogeneity was low. Habitual gait speed outcomes were measured in 13 participants and increased (0.18m/s, 95% CI -0.02, 0.38m/s, exceeding moderate important change (0.14m/s for PD cohorts. Other outcomes appeared to improve modestly in most participants.Scarce research investigating exercise in LBD exists. This review confirms

  12. Ransom, Religion, and Red Giants: C.S. Lewis and Fred Hoyle

    Science.gov (United States)

    Larsen, Kristine

    2010-01-01

    Famed fantasy writer C.S. Lewis (1898-1963) was known to friends as a well-read astronomy aficionado. However, this medieval scholar and Christian apologist embraced a pre-Copernican universe (with its astrological overtones) in his Chronicles of Narnia series and defended the beauty and relevance of the geocentric model in his final academic work, "The Discarded Image". In the "Ransom Trilogy” ("Out of the Silent Planet", "Perelandra", and "That Hideous Strength") philologist Ransom (loosely based on Lewis's close friend J.R.R. Tolkien) travels to Lewis's visions of Mars and Venus, where he interacts with intelligent extraterrestrials, battles with evil scientists, and aids in the continuation of extraterrestrial Christian values. In the final book, Ransom is joined by a handful of colleagues in open warfare against the satanic N.I.C.E. (National Institute for Coordinated Experiments). Geneticist and evolutionary biologist J.B.S. Haldane criticized Lewis for his scientifically inaccurate descriptions of the planets, and his disdain for the scientific establishment. Lewis responded to the criticism in essays of his own. Another of Lewis's favorite scientific targets was atheist Fred Hoyle, whom he openly criticized for anti-Christian statements in Hoyle's BBC radio series. Writer and Lewis friend Dorothy L. Sayers voiced her own criticism of Hoyle. In a letter, Lewis dismissed Hoyle as "not a great philosopher (and none of my scientific colleagues think much of him as a scientist.” Given Lewis's lack of respect for Hoyle, and use of creative license in describing the planets, and the flat-earth, "geocentric” Narnia, it is surprising that Lewis very carefully includes an astronomically correct description of red giants in two novels in the Narnia series ("The Magician's Nephew" and "The Last Battle"). This inclusion is even more curious given that Fred Hoyle is well-known as one of the pioneers in the field of stellar death and the properties of red giants.

  13. The chemistry of Magela Creek. A baseline for assessing change downstream of Ranger. Supervising Scientist report 151

    International Nuclear Information System (INIS)

    Klessa, D.A.

    2000-01-01

    The compositions of waters in Magela Creek upstream and downstream of Ranger uranium mine were reviewed. The water quality parameters examined were pH, electrical conductivity (EC) and turbidity, and dissolved calcium, magnesium, sodium, potassium, chloride, sulphate, ammonium, nitrate, copper, lead, manganese, zinc, uranium and radium-226. The frequency distributions of each of these parameters in waters upstream of the mine were characterised and statistically described to provide a baseline which allows a change in water chemistry downstream of the mine to be assessed. With the exception of pH, EC, turbidity, magnesium, calcium, sodium and manganese, data that comprise the baseline are not normally distributed. The frequency distributions of copper, lead, zinc, uranium and radium-226 forming the baseline are characterised by a large proportion of values at or near analytical detection limits and contamination in a relatively large proportion of the remainder. A comparison of upstream and downstream data shows that there is good conformity in pH, EC, turbidity, sodium, potassium and chloride. For calcium, nitrate, ammonium, lead, uranium, radium and zinc less than 40% of the downstream data fall outside the 20th and 80th baseline percentiles but in the ease of U, data are biased towards relatively high values. More than 40% of downstream magnesium and sulphate data are outside these percentile boundaries and are skewed towards relatively high concentrations. Copper, lead and zinc in mine waters (characterised by the composition of waters contained in the former RP4) do not appear to pose a risk as contaminants based upon the results of toxicity testing and water quality guideline trigger levels with risk minimised for greater than 1 in 20 dilution

  14. A mannequin study of intubation with the AP advance and GlideScope Ranger videolaryngoscopes and the Macintosh laryngoscope.

    Science.gov (United States)

    Hodd, Jack A R; Doyle, D John; Gupta, Shipra; Dalton, Jarrod E; Cata, Juan P; Brewer, Edward J; James, Monyulona; Sessler, Daniel I

    2011-10-01

    The AP Advance (APA) is a videolaryngoscope with interchangeable blades: intubators can choose standard Macintosh blades or a difficult-airway blade with increased curvature and a channel to guide the tube to the larynx. The APA may therefore be comparably effective in both normal and difficult airways. We tested the hypotheses that intubation with the APA is no slower than Macintosh laryngoscopy for normal mannequin airways, and that it is no slower than videolaryngoscopy using a GlideScope Ranger in difficult mannequin airways. Medical professionals whose roles potentially include tracheal intubation were trained with each device. Participants intubated simulated (Laerdal SimMan) normal and difficult airways with the APA, GlideScope, and a conventional Macintosh blade. Speed of intubation was compared using Cox proportional hazards regression, with a hazard ratio >0.8 considered noninferior. We also compared laryngeal visualization, failures, and participant preferences. Unadjusted intubation times in the normal airway with the APA and Macintosh were virtually identical (median, 22 vs 23 seconds); after adjustment for effects of experience, order, and period, the hazard ratio (95% confidence interval) comparing APA with Macintosh laryngoscopy was 0.87 (0.65, 1.17), which was not significantly more than our predefined noninferiority boundary of 0.8 (P = 0.26). Intubation with the APA was faster than with the GlideScope in difficult airways (hazard ratio = 7.6 [5.0, 11.3], P APA, whereas 33% and 37% failed with the GlideScope and Macintosh, respectively. In the difficult airway, 99% of participants achieved a Cormack and Lehane grade I to II view with the APA, versus 85% and 33% with the GlideScope and Macintosh, respectively. When asked to choose 1 device overall, 82% chose the APA. Intubation times were similar with the APA and Macintosh laryngoscopes in mannequins with normal airways. However, intubation with the APA was significantly faster than with the Glide

  15. File list: NoD.Lng.05.AllAg.Carcinoma,_Lewis_Lung [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Lng.05.AllAg.Carcinoma,_Lewis_Lung mm9 No description Lung Carcinoma, Lewis Lun...g http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/NoD.Lng.05.AllAg.Carcinoma,_Lewis_Lung.bed ...

  16. File list: InP.Lng.50.AllAg.Carcinoma,_Lewis_Lung [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Lng.50.AllAg.Carcinoma,_Lewis_Lung mm9 Input control Lung Carcinoma, Lewis Lung... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.Lng.50.AllAg.Carcinoma,_Lewis_Lung.bed ...

  17. File list: NoD.Lng.10.AllAg.Carcinoma,_Lewis_Lung [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Lng.10.AllAg.Carcinoma,_Lewis_Lung mm9 No description Lung Carcinoma, Lewis Lun...g http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/NoD.Lng.10.AllAg.Carcinoma,_Lewis_Lung.bed ...

  18. Environmental significance of copper, lead, manganese, uranium and zinc speciation in the event of contaminated waters release from the Ranger Uranium Mining Complex

    International Nuclear Information System (INIS)

    Noller, B.N.; Currey, N.A.

    1983-01-01

    The likely impact of the accidental release of tailings dam water during the dry season at the Ranger Uranium Mining Complex was examined. A speciation scheme utilising sizing by filtration and ion-exchange with Chelex 100 has given an insight into the likely partitioning of zinc, copper, lead, manganese and uranium following the addition of tailings dam water to samples from waterbodies in the vicinity of the uranium mining/milling complex. The speciation findings are discussed in terms of likely toxic effects on fish

  19. DOE/NASA Lewis large-wind-turbine program

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, R.L.

    1982-01-01

    There are several ongoing large wind system development project; ots directed toward meeting the technology requirements for utility applications. First generation tehcnology machines (Mod-0A and Mod-1) and second generation machines (Mod-2) are in opoeration at selected utility sites. Third generation technology machines (Mod-5) are in the design phase and are scheduled for initial operation in 1984 if project funding is continued. An overview of the large wind turbine activities managed by NASA Lewis is provided. These activities include results from the first and second generation field machines (Mod-0A, 01, and -2), the status of the Department of Interior WTS-4 machine for which NASA is responsible for technical management, and the design phase of the third generation wind turbines (Mod-5).

  20. Renal Failure in Dementia with Lewy Bodies Presenting as Catatonia

    Science.gov (United States)

    Fekete, Robert

    2013-01-01

    Catatonia, originally described by Karl Kahlbaum in 1874, may be regarded as a set of clinical features found in a subtype of schizophrenia, but the syndrome may also stem from organic causes including vascular parkinsonism, brain masses, globus pallidus lesions, metabolic derangements, and pharmacologic agents, especially first generation antipsychotics. Catatonia may include paratonia, waxy flexibility (cerea flexibilitas), stupor, mutism, echolalia, and catalepsy (abnormal posturing). A case of catatonia as a result of acute renal failure in a patient with dementia with Lewy bodies is described. This patient recovered after intravenous fluid administration and reinstitution of the atypical dopamine receptor blocking agent quetiapine, but benzodiazepines and amantadine are additional possible treatments. Recognition of organic causes of catatonia leads to timely treatment and resolution of the syndrome. PMID:23466522

  1. Renal Failure in Dementia with Lewy Bodies Presenting as Catatonia

    Directory of Open Access Journals (Sweden)

    Robert Fekete

    2013-01-01

    Full Text Available Catatonia, originally described by Karl Kahlbaum in 1874, may be regarded as a set of clinical features found in a subtype of schizophrenia, but the syndrome may also stem from organic causes including vascular parkinsonism, brain masses, globus pallidus lesions, metabolic derangements, and pharmacologic agents, especially first generation antipsychotics. Catatonia may include paratonia, waxy flexibility (cerea flexibilitas, stupor, mutism, echolalia, and catalepsy (abnormal posturing. A case of catatonia as a result of acute renal failure in a patient with dementia with Lewy bodies is described. This patient recovered after intravenous fluid administration and reinstitution of the atypical dopamine receptor blocking agent quetiapine, but benzodiazepines and amantadine are additional possible treatments. Recognition of organic causes of catatonia leads to timely treatment and resolution of the syndrome.

  2. Survey on Cosmogenic 26Al in Lewis Cliff Meteorites

    Science.gov (United States)

    Welten, K. C.; Alderliesten, C.; Lindner, L.

    1992-07-01

    INTRODUCTION: We have embarked upon a ^26Al gamma-ray survey of meteorites selected from about 2000 samples recently recovered from the Lewis Cliff Ice Fields (84 degrees 18'S/161 degrees 20'E). Due to its 705-ka half-life ^26Al can be used for estimating terrestrial ages and thus contribute to further characterization of Antarctic meteorites in addition to their classification and thermoluminescence (TL) properties. The ^26Al survey is also useful for identifying meteorites with unusual exposure histories, which merit additional measurements of cosmogenic radionuclides (by AMS) and noble gases. In addition, it provides clues on possible pairings. METHOD: Low-level gamma-ray spectroscopy is well suited for ^26Al survey work, since bulk meteorite samples can be measured routinely and nondestructively without any previous sample preparation. The required size of the samples (30-500 g) makes the method relatively independent of depth effects and compositional inhomogeneities. The use of a high-resolution GeLi detector also allows the determination of the natural ^40K activity and thus the K content of the samples, which can be used as an additional pairing criterion for ordinary chondrites. Also ^137Cs, a fall-out surface contamination [1], is simultaneously measured; low values may be characteristic for meteorites recently fallen or released from the ablating ice. For the detector an efficiency calibration curve has been made that adequately accounts for differences in size and shape of the meteorite samples. RESULTS and DISCUSSION: TERRESTRIAL AGES: So far, we have measured over 30 Lewis Cliff equilibrated H and L chondrites, collected from widely differing locations. Normalized to L-chondrite composition, the ^26Al contents range from 27 to 110 dpm/kg with peaks around 43 and 53 dpm/kg. This bimodal ^26Al distribution is reminiscent of that observed for Allan Hills ordinary chondrites [2]. Tentative terrestrial ages, calculated on the basis of ^26Al saturation

  3. Transport Coefficients for the NASA Lewis Chemical Equilibrium Program

    Science.gov (United States)

    Svehla, Roger A.

    1995-01-01

    The new transport property data that will be used in the NASA Lewis Research Center's Chemical Equilibrium and Applications Program (CEA) is presented. It complements a previous publication that documented the thermodynamic and transport property data then in use. Sources of the data and a brief description of the method by which the data were obtained are given. Coefficients to calculate the viscosity, thermal conductivity, and binary interactions are given for either one, or usually, two temperature intervals, typically 300 to 1000 K and 1000 to 5000 K. The form of the transport equation is the same as used previously. The number of species was reduced from the previous database. Many species for which the data were estimated were eliminated from the database. Some ionneutral interactions were added.

  4. A comparison of two instructional methods for drawing Lewis Structures

    Science.gov (United States)

    Terhune, Kari

    Two instructional methods for teaching Lewis structures were compared -- the Direct Octet Rule Method (DORM) and the Commonly Accepted Method (CAM). The DORM gives the number of bonds and the number of nonbonding electrons immediately, while the CAM involves moving electron pairs from nonbonding to bonding electrons, if necessary. The research question was as follows: Will high school chemistry students draw more accurate Lewis structures using the DORM or the CAM? Students in Regular Chemistry 1 (N = 23), Honors Chemistry 1 (N = 51) and Chemistry 2 (N = 15) at an urban high school were the study participants. An identical pretest and posttest was given before and after instruction. Students were given instruction with either the DORM (N = 45), the treatment method, or the CAM (N = 44), the control for two days. After the posttest, 15 students were interviewed, using a semistructured interview process. The pretest/posttest consisted of 23 numerical response questions and 2 to 6 free response questions that were graded using a rubric. A two-way ANOVA showed a significant interaction effect between the groups and the methods, F (1, 70) = 10.960, p = 0.001. Post hoc comparisons using the Bonferroni pairwise comparison showed that Reg Chem 1 students demonstrated larger gain scores when they had been taught the CAM (Mean difference = 3.275, SE = 1.324, p Chemistry 1 students performed better with the DORM, perhaps due to better math skills, enhanced working memory, and better metacognitive skills. Regular Chemistry 1 students performed better with the CAM, perhaps because it is more visual. Teachers may want to use the CAM or a direct-pairing method to introduce the topic and use the DORM in advanced classes when a correct structure is needed quickly.

  5. District Energy Windsor

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    This paper presents a summary of how District Energy Windsor operates. It includes a system site map and reasons why it is advantageous to get connected to a district heating system. District Energy Windsor is a division of the Windsor Utilities Commission. It was developed in 1996 and was the first in North America to supply both heating and cooling requirements. It supplies nearly 2 million square feet of heating and cooling for Windsor's city centre. The district energy system produces hot water or chilled water at a central plant. Energy is then piped out to buildings in the area, including the Art Gallery of Windsor, the Royal Bank Business Centre, the Windsor Justice Facility, the Windsor Casino, and Northwind Windsor. The energy, which is transferred through heat exchangers, is used for space heating, domestic hot water heating, and air conditioning. The 8 reasons for getting connected are: (1) less management costs, (2) lower energy costs, (3) lower level of risk management, (4) stable energy rates, (5) better use of building space, (6) reliable service, (7) reduced expansion costs, and (8) a cleaner environment. District heating improves air quality through reduced carbon dioxide and nitrogen oxide emissions. In addition, fuel delivery and storage are eliminated. figs.

  6. Lewis pair polymerization by classical and frustrated Lewis pairs: Acid, base and monomer scope and polymerization mechanism

    KAUST Repository

    Zhang, Yuetao

    2012-01-01

    Classical and frustrated Lewis pairs (LPs) of the strong Lewis acid (LA) Al(C 6F 5) 3 with several Lewis base (LB) classes have been found to exhibit exceptional activity in the Lewis pair polymerization (LPP) of conjugated polar alkenes such as methyl methacrylate (MMA) as well as renewable α-methylene-γ-butyrolactone (MBL) and γ-methyl- α-methylene-γ-butyrolactone (γ-MMBL), leading to high molecular weight polymers, often with narrow molecular weight distributions. This study has investigated a large number of LPs, consisting of 11 LAs as well as 10 achiral and 4 chiral LBs, for LPP of 12 monomers of several different types. Although some more common LAs can also be utilized for LPP, Al(C 6F 5) 3-based LPs are far more active and effective than other LA-based LPs. On the other hand, several classes of LBs, when paired with Al(C 6F 5) 3, can render highly active and effective LPP of MMA and γ-MMBL; such LBs include phosphines (e.g., P tBu 3), chiral chelating diphosphines, N-heterocyclic carbenes (NHCs), and phosphazene superbases (e.g., P 4- tBu). The P 4- tBu/Al(C 6F 5) 3 pair exhibits the highest activity of the LP series, with a remarkably high turn-over frequency of 9.6 × 10 4 h -1 (0.125 mol% catalyst, 100% MMA conversion in 30 s, M n = 2.12 × 10 5 g mol -1, PDI = 1.34). The polymers produced by LPs at RT are typically atactic (P γMMBL with ∼47% mr) or syndio-rich (PMMA with ∼70-75% rr), but highly syndiotactic PMMA with rr ∼91% can be produced by chiral or achiral LPs at -78 °C. Mechanistic studies have identified and structurally characterized zwitterionic phosphonium and imidazolium enolaluminates as the active species of the current LPP system, which are formed by the reaction of the monomer·Al(C 6F 5) 3 adduct with P tBu 3 and NHC bases, respectively. Kinetic studies have revealed that the MMA polymerization by the tBu 3P/ Al(C 6F 5) 3 pair is zero-order in monomer concentration after an initial induction period, and the polymerization

  7. District heating in Flensburg

    Energy Technology Data Exchange (ETDEWEB)

    Prinz, W.

    1981-01-01

    The majority of our population, but also of our authorities, are still skeptical or even disapproving towards district heating. The reasons of this negative attitude are partly psychological - e.g. the individualism of the Swiss and their dislike for too centralised structures and ''forced connections'' - but also the existence of finished gas supply networks and the fear of considerable pre-investments and torn streets over years. The following article - held as a speech on the information meeting ''District heating and the possible contribution of nuclear energy'' organised by the Swiss Association for Atomic Energy in Bern shows a practical problem solving at the example of the district heating in Flensburg and deals with these questions.

  8. Empowerment Zones and Enterprise Districts - MDC_CommunityDevelopmentDistrict

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Community Development Districts (CDDs) are special taxing districts or local units of special-purpose government. A CDD may charge separate non-ad valorem special...

  9. Temporal trends in erosion and hydrology for a post-mining landform at Ranger mine, Northern Territory. Supervising Scientist report 165

    International Nuclear Information System (INIS)

    Moliere, D.R.; Evans, K.G.; Saynor, M.J.; Willgoose, G.R.

    2002-01-01

    An important part of rehabilitation planning for mines is the design of a stable landform for waste rock dumps or spoil piles, at the completion of mining, which minimise erosion and environmental impact offsite. To successfully incorporate landform designs in planning, there is a need to be able to predict the surface stability of the final landform using erosion and landform evolution modelling techniques. In the long term, weathering, soil forming processes, ecosystem development and even climate change may affect the surface characteristics, and hence the stability, of the rehabilitated landform. In this study, changes to the surface characteristics of a landform in time can be quantified in terms of erosion parameters. Since a prediction of the stability of the rehabilitated landform is required over the long term, temporal changes in these erosion parameters are incorporated into landform evolution modelling of a post-mining landform. The landform evolution model SIBERIA was used to predict the stability of the proposed rehabilitated landform at Ranger Mine, Northern Territory. The data collection sites were considered to be representative of the hydrology and erosion characteristics that would exist on the WRD at Ranger at various stages after rehabilitation. This study uses measured site data from landforms with hydrology and erosion properties similar to those likely to develop on Ranger at various times after rehabilitation to assess the effect of temporal change on landform evolution model input parameters. Section 2 documents the process of SIBERIA input parameter derivation and landform evolution modelling using collected site rainfall, runoff and sediment loss data. This section is based on the detailed descriptions of the process given in Willgoose and Riley (1998) and Evans et al( 1998). In section 3, monitoring data, collected from sites with properties similar to those likely to develop on the proposed above-grade landform at Ranger at various

  10. Interim district energy implementation

    Energy Technology Data Exchange (ETDEWEB)

    Fearnley, R.; Susak, W. [City of Vancouver, BC (Canada); Johnstone, I. [BCG Services Inc., Vancouver, BC (Canada)

    2001-07-01

    The concept of district energy was introduced in the City of North Vancouver, a city of 45,000, in 1997. A preliminary study was completed in 1997, followed by a tour of some district energy facilities in Finland in the same year. In 1999 a large district energy study was completed by a consultant. The study indicated the need for an investment of $15 million to implement district heating in the City. Lack of sufficient financial resources and immediately connectable heat load, the project was considered a non-starter. Some of the other factors leading to shelving the project included no current significant pricing advantages over competing energy sources and no current opportunity for cogeneration, given the low price that BC Hydro is willing to pay for independently produced power. The project, although shelved for the moment, has not been discarded. Planning and exploration are continuing, aided by the City's commitment to energy efficiency and conservation, its long term planning horizon and its significant influence over the development of some prime real estate.

  11. Jordan Lake Watershed Protection District

    Data.gov (United States)

    Town of Chapel Hill, North Carolina — Polygon representing the area of the Jordan Lake Watershed Protection District. The Watershed Protection District (PDF) is a sensitive area of land that drains to...

  12. New Mexico State Forestry Districts

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries of the New Mexico Forestry Districts, plus the names of the district offices. It is in a vector digital structure digitized from a...

  13. From Conventional Lewis Acids to Heterogeneous Montmorillonite K10: Eco-Friendly Plant-Based Catalysts Used as Green Lewis Acids.

    Science.gov (United States)

    Hechelski, Marie; Ghinet, Alina; Louvel, Brice; Dufrénoy, Pierrick; Rigo, Benoît; Daïch, Adam; Waterlot, Christophe

    2018-04-25

    The concept of green chemistry began in the USA in the 1990s. Since the publication of the 12 principles of this concept, many reactions in organic chemistry have been developed, and chemical products have been synthesized under environmentally friendly conditions. Lewis acid mediated synthetic transformations are by far the most numerous and best studied. However, the use of certain Lewis acids may cause risks to environmental and human health. This Review discusses the evolution of Lewis acid catalyzed reactions from a homogeneous liquid phase to the solid phase to yield the expected organic molecules under green, safe conditions. In particular, recent developments and applications of biosourced catalysts from plants are highlighted. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Lewis Research Center studies of multiple large wind turbine generators on a utility network

    Science.gov (United States)

    Gilbert, L. J.; Triezenberg, D. M.

    1979-01-01

    A NASA-Lewis program to study the anticipated performance of a wind turbine generator farm on an electric utility network is surveyed. The paper describes the approach of the Lewis Wind Energy Project Office to developing analysis capabilities in the area of wind turbine generator-utility network computer simulations. Attention is given to areas such as, the Lewis Purdue hybrid simulation, an independent stability study, DOE multiunit plant study, and the WEST simulator. Also covered are the Lewis mod-2 simulation including analog simulation of a two wind turbine system and comparison with Boeing simulation results, and gust response of a two machine model. Finally future work to be done is noted and it is concluded that the study shows little interaction between the generators and between the generators and the bus.

  15. 2009 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Lewis County, Washington

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Watershed Sciences, Inc. (WSI) collected Light Detection and Ranging (LiDAR) data for the Lewis County survey area for the Puget Sound LiDAR Consortium. This data...

  16. 2005 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Lewis County

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Terrapoint collected Light Detection and Ranging (LiDAR) data for the Lewis County project of 2005. The project site covered approximately 223 square miles, divided...

  17. Functional connectivity in cortical regions in dementia with Lewy bodies and Alzheimer's disease.

    Science.gov (United States)

    Kenny, Eva R; Blamire, Andrew M; Firbank, Michael J; O'Brien, John T

    2012-02-01

    Using resting-state functional magnetic resonance imaging, spontaneous low-frequency fluctuations in the blood oxygenation level-dependent signal were measured to investigate connectivity between key brain regions hypothesized to be differentially affected in dementia with Lewy bodies compared with Alzheimer's disease and healthy controls. These included connections of the hippocampus, because of its role in learning, and parietal and occipital areas involved in memory, attention and visual processing. Connectivity was investigated in 47 subjects aged 60 years and over: 15 subjects with dementia with Lewy bodies, 16 subjects with Alzheimer's disease and 16 control subjects. Subjects were scanned using a 3 Tesla magnetic resonance imaging system. The mean blood oxygenation level-dependent signal time series was extracted from seed regions in the hippocampus, posterior cingulate cortex, precuneus and primary visual cortex and correlated with all other brain voxels to determine functional connectivity. Both subjects with dementia with Lewy bodies and Alzheimer's disease showed greater connectivity than control subjects. Compared with controls, the dementia with Lewy bodies group had greater connectivity between the right posterior cingulate cortex and other brain areas. In dementia with Lewy bodies, there were no significant differences in hippocampal connectivity compared with controls, but in Alzheimer's disease left hippocampal connectivity was greater compared with controls. There were no significant differences between groups for precuneus or primary visual cortex connectivity. No seed regions showed significantly less connectivity in subjects with dementia with Lewy bodies or Alzheimer's disease compared with controls. We found greater connectivity with the posterior cingulate in dementia with Lewy bodies and with the hippocampus in Alzheimer's disease. Consistent with the known relative preservation of memory in dementia with Lewy bodies compared with Alzheimer

  18. District Consolidation: Rivals Coming Together

    Science.gov (United States)

    Mart, Dan

    2011-01-01

    District consolidation is a highly emotional process. One key to success is sticking to the facts. In Iowa, school districts facing financial difficulties or enrollment concerns do not have to move directly to consolidation. In many cases, districts begin by developing sharing agreements. These sharing agreements may start with simple sharing of…

  19. 7 CFR 917.14 - District.

    Science.gov (United States)

    2010-01-01

    ... District. (g) Contra Costa District includes and consists of Contra Costa County. (h) Santa Clara District... Ventura County. (l) Stockton District includes and consists of San Joaquin County, Amador County...

  20. Clinical and imaging correlates of amyloid deposition in dementia with Lewy bodies.

    Science.gov (United States)

    Donaghy, Paul C; Firbank, Michael J; Thomas, Alan J; Lloyd, Jim; Petrides, George; Barnett, Nicola; Olsen, Kirsty; O'Brien, John T

    2018-04-19

    Amyloid deposition is common in dementia with Lewy bodies, but its pathophysiological significance is unclear. The objective of this study was to investigate the relationship between amyloid deposition and clinical profile, gray matter volume, and brain perfusion in dementia with Lewy bodies. Dementia with Lewy bodies (n = 37), Alzheimer's disease (n = 20), and controls (n = 20) underwent a thorough clinical assessment, 3T MRI, and early- and late-phase 18 F-Florbetapir PET-CT to assess cortical perfusion and amyloid deposition, respectively. Amyloid scans were visually categorized as positive or negative. Image analysis was carried out using statistical parametric mapping (SPM) 8. There were no significant differences between amyloid-positive and amyloid-negative dementia with Lewy bodies cases in age (P = .78), overall cognitive impairment (P = .83), level of functional impairment (P = .80), or any other clinical or cognitive scale. There were also no significant differences in hippocampal or gray matter volumes. However, amyloid-positive dementia with Lewy bodies cases had lower medial temporal lobe perfusion (P = .03) than amyloid-negative cases, although a combination of medial temporal lobe perfusion, hippocampal volume, and cognitive measures was unable to accurately predict amyloid status in dementia with Lewy bodies. Amyloid deposition was not associated with differences in clinical or neuropsychological profiles in dementia with Lewy bodies, but was associated with imaging evidence of medial temporal lobe dysfunction. The presence of amyloid in dementia with Lewy bodies cannot be identified on the basis of clinical and other imaging features and will require direct assessment via PET imaging or CSF. © 2018 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society. © 2018 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf

  1. Visual Hallucinations in PD and Lewy Body Dementias: Old and New Hypotheses

    Directory of Open Access Journals (Sweden)

    M. Onofrj

    2013-01-01

    Full Text Available Visual Hallucinations (VH are a common non-motor symptom of Parkinson’s Disease (PD and the Lewy body dementias (LBD of Parkinson's disease with dementia (PDD and Dementia with Lewy Bodies (DLB. The origin of VH in PD and LBD is debated: earlier studies considered a number of different possible mechanisms underlying VH including visual disorders, Rapid Eye Movement (REM Sleep Intrusions, dysfunctions of top down or bottom up visual pathways, and neurotransmitter imbalance.

  2. A dual Lewis base activation strategy for enantioselective carbene-catalyzed annulations.

    Science.gov (United States)

    Izquierdo, Javier; Orue, Ane; Scheidt, Karl A

    2013-07-24

    A dual activation strategy integrating N-heterocyclic carbene (NHC) catalysis and a second Lewis base has been developed. NHC-bound homoenolate equivalents derived from α,β-unsaturated aldehydes combine with transient reactive o-quinone methides in an enantioselective formal [4 + 3] fashion to access 2-benzoxopinones. The overall approach provides a general blueprint for the integration of carbene catalysis with additional Lewis base activation modes.

  3. Lewis antigen mediated adhesion of freshly removed human bladder tumors to E-selectin

    DEFF Research Database (Denmark)

    Skorsteensgaard, Karna; Vestergaard, Else Marie; Langkilde, Niels

    1999-01-01

    PURPOSE: Twenty fresh surgical specimens of human bladder tumors were tested for their ability to adhere to recombinant P and E-selectin. The adhesion was correlated to immunological detection of carbohydrate structures. MATERIALS AND METHODS: A static titertray assay with immobilized selectins.......003), whereas no correlation was found to secretor and Lewis genotypes. CONCLUSIONS: These data on clinical specimens indicate that Lewis antigen mediated E-selectin adhesion may play a role in the human bladder cancer disease....

  4. Fate of TCE in heated Fort Lewis soil.

    Science.gov (United States)

    Costanza, Jed; Fletcher, Kelly E; Löffler, Frank E; Pennell, Kurt D

    2009-02-01

    This study explores the transformation of trichloroethene (TCE) caused by heating contaminated soil and groundwater samples obtained from the East Gate Disposal Yard (EGDY) located in Fort Lewis, WA. After field samples transferring into glass ampules and introducing 1.5 micromol of TCE, the sealed ampules were incubated at temperatures of 25, 50, and 95 degrees C for periods of up to 95.5 days. Although TCE was completely transformed into cis-1,2-dichloroethene (cis-DCE) after 42 days at 25 degrees C by microbial activity, this transformation was not observed at 50 or 95 degrees C. Chloride levels increased after 42 days at 25 degrees C corresponding to the mass of TCE transformed to cis-DCE, were constant at 50 degrees C, and increased at 95 degrees C yielding a TCE degradation half-life of 1.6-1.9 years. These findings indicate that indigenous microbes contribute to the partial dechlorination of TCE to cis-DCE at temperatures of less than 50 degrees C, whereas interphase mass transfer and physical recovery of TCE will predominate over in situ degradation processes at temperatures of greater than 50 degrees C during thermal treatment at the EGDY site.

  5. NASA Lewis steady-state heat pipe code users manual

    International Nuclear Information System (INIS)

    Tower, L.K.

    1992-06-01

    The NASA Lewis heat pipe code has been developed to predict the performance of heat pipes in the steady state. The code can be used as a design tool on a personal computer or, with a suitable calling routine, as a subroutine for a mainframe radiator code. A variety of wick structures, including a user input option, can be used. Heat pipes with multiple evaporators, condensers, and adiabatic sections in series and with wick structures that differ among sections can be modeled. Several working fluids can be chosen, including potassium, sodium, and lithium, for which the monomer-dimer equilibrium is considered. The code incorporates a vapor flow algorithm that treats compressibility and axially varying heat input. This code facilitates the determination of heat pipe operating temperatures and heat pipe limits that may be encountered at the specified heat input and environment temperature. Data are input to the computer through a user-interactive input subroutine. Output, such as liquid and vapor pressures and temperatures, is printed at equally spaced axial positions along the pipe as determined by the user

  6. Lewis Swift celebrated comet hunter and the people's astronomer

    CERN Document Server

    Kronk, Gary W

    2017-01-01

    This biography covers the life of Lewis Swift (1820-1913), who discovered 13 comets and nearly 1,200 other deep sky objects. All 13 comets found by Swift now bear his name, including three periodic comets with periods of 6 years (11P/Tempel-Swift-LINEAR), 9 years (64P/Swift-Gehrels), and 133 years (109P/Swift-Tuttle). Swift's enthusiasm and success as an amateur astronomer helped make him famous in the United States. With the help of others, Swift was able to buy a 16-inch refractor, the third largest telescope in the United States at the time. Hulbert Harrington Warner built "Warner Observatory" to house this telescope. As a prolific writer and lecturer, Swift's stories appeared in newspapers and magazines, while his lectures showed that he was able to explain anything in a way that everyone could understand.  When Warner went broke during the "Panic of 1893," Swift was forced to leave his home. Almost two dozen invitations arrived from around the United States asking him to bring his telescope to their ci...

  7. Clinical and neuroimage findings of dementia with lewy bodies

    International Nuclear Information System (INIS)

    Kang, Do Young; Park, Kyung Won; Kim, Jae Woo

    2002-01-01

    Dementia with lewy bodies (DLB) is the second common degenerative dementia and has several characteristics including fluctuating cognition, visual hallucination and Parkinsonism. We investigated clinical manifestations and neuroimaging findings in DLB patients. Ten probable DLB patients were included in this study. Brain MRI, Tc-99m HMPAO brain perfusion SPECT and I-123 IPT SPECT were performed. All patients were men and mean age of onset was 64.2 years (range from 54 to 80). All had fluctuating cognition and Parkinsonism, and 8 had visual hallucination. Dementia preceded Parkinsonism in 3 patients. Fluctuation of K-MMSE ranges from 3 to 8 points. Rest tremor was seen in 5 patients. Brain MRI showed cortical atrophy in all patients. Tc-99m brain perfusion SPECT showed hypoperfusion in occipital area as well as fronto-temporo-parietal areas. I-123 IPT SPECT revealed reduced uptake comparable to Parkinson's disease in the striatum. DLB should be first considered as one of possible diagnosis in patients showing dementia in the early stage of Parkinsonism. Hypoperfusion in the occipital area was thought to be a characteristic finding in DLB and to be helpful in differentiating DLB from other degenerative dementias

  8. Microfluidic Separation of Ethylene and Ethane Using Frustrated Lewis Pairs.

    Science.gov (United States)

    Voicu, Dan; Stephan, Douglas W; Kumacheva, Eugenia

    2015-12-21

    Separation of gaseous olefins and paraffins is one of the most important separation processes in the industry. Development of new cost-effective technologies aims at reducing the high energy consumption during the separation process. Here, we took advantage of the reaction of frustrated Lewis pairs (FLPs) with ethylene to achieve reactive extraction of ethylene from ethylene-ethane mixtures. The extraction was studied using a microfluidic platform, which enabled a rapid, high-throughput assessment of reaction conditions to optimize gas separation efficiency. A separation factor of 7.3 was achieved for ethylene from a 1:1 volume ratio mixture of ethylene and ethane, which corresponded to an extracted ethylene purity of 88 %. The results obtained in the microfluidic studies were validated using infrared spectroscopy. This work paves the way for further development of the FLPs and optimization of reaction conditions, thereby maximizing the separation efficiency of olefins from their mixtures with paraffins. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Streamline segment statistics of premixed flames with nonunity Lewis numbers

    Science.gov (United States)

    Chakraborty, Nilanjan; Wang, Lipo; Klein, Markus

    2014-03-01

    The interaction of flame and surrounding fluid motion is of central importance in the fundamental understanding of turbulent combustion. It is demonstrated here that this interaction can be represented using streamline segment analysis, which was previously applied in nonreactive turbulence. The present work focuses on the effects of the global Lewis number (Le) on streamline segment statistics in premixed flames in the thin-reaction-zones regime. A direct numerical simulation database of freely propagating thin-reaction-zones regime flames with Le ranging from 0.34 to 1.2 is used to demonstrate that Le has significant influences on the characteristic features of the streamline segment, such as the curve length, the difference in the velocity magnitude at two extremal points, and their correlations with the local flame curvature. The strengthenings of the dilatation rate, flame normal acceleration, and flame-generated turbulence with decreasing Le are principally responsible for these observed effects. An expression for the probability density function (pdf) of the streamline segment length, originally developed for nonreacting turbulent flows, captures the qualitative behavior for turbulent premixed flames in the thin-reaction-zones regime for a wide range of Le values. The joint pdfs between the streamline length and the difference in the velocity magnitude at two extremal points for both unweighted and density-weighted velocity vectors are analyzed and compared. Detailed explanations are provided for the observed differences in the topological behaviors of the streamline segment in response to the global Le.

  10. Liquid-Phase Catalytic Transfer Hydrogenation of Furfural over Homogeneous Lewis Acid-Ru/C Catalysts.

    Science.gov (United States)

    Panagiotopoulou, Paraskevi; Martin, Nickolas; Vlachos, Dionisios G

    2015-06-22

    The catalytic performance of homogeneous Lewis acid catalysts and their interaction with Ru/C catalyst are studied in the catalytic transfer hydrogenation of furfural by using 2-propanol as a solvent and hydrogen donor. We find that Lewis acid catalysts hydrogenate the furfural to furfuryl alcohol, which is then etherified with 2-propanol. The catalytic activity is correlated with an empirical scale of Lewis acid strength and exhibits a volcano behavior. Lanthanides are the most active, with DyCl3 giving complete furfural conversion and a 97 % yield of furfuryl alcohol at 180 °C after 3 h. The combination of Lewis acid and Ru/C catalysts results in synergy for the stronger Lewis acid catalysts, with a significant increase in the furfural conversion and methyl furan yield. Optimum results are obtained by using Ru/C combined with VCl3 , AlCl3 , SnCl4 , YbCl3 , and RuCl3 . Our results indicate that the combination of Lewis acid/metal catalysts is a general strategy for performing tandem reactions in the upgrade of furans. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Lewis Carroll, a educação e o ensino de geometria na Inglaterra vitoriana - Lewis Carroll, education and the teaching of geometry in victorian England

    Directory of Open Access Journals (Sweden)

    Rafael Montoito

    2015-04-01

    Full Text Available Parte da pesquisa motivada pela tradução para o português do livro Euclides e seus rivais modernos, publicado por Lewis Carroll em 1879, este artigo se inscreve numa série de estudos que visam a um exame hermenêutico dessa obra. São discutidos temas relacionados com a educação, a educação matemática e o ensino de geometria na Inglaterra vitoriana.Palavras-chave: Lewis Carroll, Euclides e seus rivais modernos, história da educação, educação matemática, geometria. LEWIS CARROLL, EDUCATION AND THE TEACHING OF GEOMETRY IN VICTORIAN ENGLANDAbstractResearch partly motivated by Lewis Carrroll's Euclid and his modern rivals (1879 portuguese translation, this paper presents some hermeneutical remarks taken as necessary to understand the context in which such book was produced. The paper focuses particularly on education, in general, and on the teaching of mathematics and geometry in victorian England.Key-words: Lewis Carroll, Euclid and his modern rivals, history of education, mathematics education, geometry. LEWIS CARROLL, LA EDUCACIÓN Y EL ENSINO DE GEOMETRÍA EN LA INGLATERRA VICTORIANAResumenParte de la investigación motivada por la traducción al portugués del libro Euclides y sus enemigos modernos, publicado por Lewis Carroll en 1879, este artículo se inscribe en una serie de estudios que tienen por objetivo hacer un examen hermenéutico de la obra. Son aquí discutidos temas relacionados como la educación, la educación matemática y la enseñanza de geometría en la Inglaterra victoriana.Palabras-clave: Lewis Carroll, Euclides y sus enemigos modernos, historia de la educación, educación matemática, geometría. LEWIS CARROLL, L’ÉDUCATION ET L’ENSEIGMENT DE GÉOMÉTRIE EN L’ANGLETERRE VICTORIENNERésuméFaisant partie de la recherche motivée par la traduction en portugais du livre Euclide et ses rivaux modernes, publié par Lewis Carrol en 1879 , cet article s’inscrit dans une série d’études dont le but

  12. VII international district heating conference

    International Nuclear Information System (INIS)

    1988-01-01

    The proceedings of the 7th International District Heating Conference contain the full texts of the 89 presented papers of which 11 fall under the INIS Subject Scope. The conference met in seven sessions and dealt with the following problem areas: design and optimization of systems of district heating, integration of the power system and the district heating systems, cooperation of nuclear and fossil burning sources in district heating systems, the use of specific nuclear power plants for heating purposes, questions of the control of systems of district heating, the development of components of heating networks, the reliability and design of heat supply pipes. (Z.M.)

  13. Comparative Proteomic Analysis of Two Uveitis Models in Lewis Rats.

    Science.gov (United States)

    Pepple, Kathryn L; Rotkis, Lauren; Wilson, Leslie; Sandt, Angela; Van Gelder, Russell N

    2015-12-01

    Inflammation generates changes in the protein constituents of the aqueous humor. Proteins that change in multiple models of uveitis may be good biomarkers of disease or targets for therapeutic intervention. The present study was conducted to identify differentially-expressed proteins in the inflamed aqueous humor. Two models of uveitis were induced in Lewis rats: experimental autoimmune uveitis (EAU) and primed mycobacterial uveitis (PMU). Differential gel electrophoresis was used to compare naïve and inflamed aqueous humor. Differentially-expressed proteins were separated by using 2-D gel electrophoresis and excised for identification with matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF). Expression of select proteins was verified by Western blot analysis in both the aqueous and vitreous. The inflamed aqueous from both models demonstrated an increase in total protein concentration when compared to naïve aqueous. Calprotectin, a heterodimer of S100A8 and S100A9, was increased in the aqueous in both PMU and EAU. In the vitreous, S100A8 and S100A9 were preferentially elevated in PMU. Apolipoprotein E was elevated in the aqueous of both uveitis models but was preferentially elevated in EAU. Beta-B2-crystallin levels decreased in the aqueous and vitreous of EAU but not PMU. The proinflammatory molecules S100A8 and S100A9 were elevated in both models of uveitis but may play a more significant role in PMU than EAU. The neuroprotective protein β-B2-crystallin was found to decline in EAU. Therapies to modulate these proteins in vivo may be good targets in the treatment of ocular inflammation.

  14. Improved lignin polyurethane properties with Lewis acid treatment.

    Science.gov (United States)

    Chung, Hoyong; Washburn, Newell R

    2012-06-27

    Chemical modification strategies to improve the mechanical properties of lignin-based polyurethanes are presented. We hypothesized that treatment of lignin with Lewis acids would increase the concentration of hydroxyl groups available to react with diisocyanate monomers. Under the conditions used, hydrogen bromide-catalyzed modification resulted in a 28% increase in hydroxyl group content. Associated increases in hydrophilicity of solvent-cast thin films were also recorded as evidenced by decreases in water contact angle. Polyurethanes were then prepared by first preparing a prepolymer based on mixtures of toluene-2,4-diisocyanate (TDI) and unmodified or modified lignin, then polymerization was completed through addition of polyethylene glycol (PEG), resulting in mass ratios of TDI:lignin:PEG of 43:17:40 in the compositions investigated here. The mixture of TDI and unmodified lignin resulted in a lignin powder at the bottom of the liquid, suggesting it did not react directly with TDI. However, a homogeneous solution resulted when TDI and the hydrogen bromide-treated lignin were mixed, suggesting demethylation indeed increased reactivity and resulted in better integration of lignin into the urethane network. Significant improvements in mechanical properties of modified lignin polyurethanes were observed, with a 6.5-fold increase in modulus, which were attributed to better integration of the modified lignin into the covalent polymer network due to the higher concentration of hydroxyl groups. This research indicates that chemical modification strategies can lead to significant improvements in the properties of lignin-based polymeric materials using a higher fraction of an inexpensive lignin monomer from renewable resources and a lower fraction an expensive, petroleum-derived isocyanate monomer to achieve the required material properties.

  15. Expression of hPNAS-4 Radiosensitizes Lewis Lung Cancer

    International Nuclear Information System (INIS)

    Zeng Hui; Yuan Zhu; Zhu Hong; Li Lei; Shi Huashan; Wang Zi; Fan Yu; Deng Qian; Zeng Jianshuang; He Yinbo; Xiao Jianghong; Li Zhiping

    2012-01-01

    Purpose: This study aimed to transfer the hPNAS-4 gene, a novel apoptosis-related human gene, into Lewis lung cancer (LL2) and observe its radiosensitive effect on radiation therapy in vitro and in vivo. Methods and Materials: The hPNAS-4 gene was transfected into LL2 cells, and its expression was detected via western blot. Colony formation assay and flow cytometry were used to detect the growth and apoptosis of cells treated with irradiation/PNAS-4 in vitro. The hPNAS-4 gene was transferred into LL2-bearing mice through tail vein injection of the liposome/gene complex. The tumor volumes were recorded after radiation therapy. Proliferating cell nuclear antigen (PCNA) immunohistochemistry staining and terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay were performed to detect the tumor cell growth and apoptosis in vivo. Results: The hPNAS-4 gene was successfully transferred into LL2 cells and tumor tissue, and its overexpressions were confirmed via western blot analysis. Compared with the control, empty plasmid, hPNAS-4, radiation, and empty plasmid plus radiation groups, the hPNAS-4 plus radiation group more significantly inhibited growth and enhanced apoptosis of LL2 cells in vitro and in vivo (P<.05). Conclusions: The hPNAS-4 gene was successfully transferred into LL2 cells and tumor tissue and was expressed in both LL2 cell and tumor tissue. The hPNAS-4 gene therapy significantly enhanced growth inhibition and apoptosis of LL2 tumor cells by radiation therapy in vitro and in vivo. Therefore, it may be a potential radiosensitive treatment of radiation therapy for lung cancer.

  16. Lewis M. Rutherfurd and the First Photograph of Solar Granulation

    Science.gov (United States)

    Harvey, J. W.; Briggs, John W.; Prosser, Sian

    2017-08-01

    A major astronomical controversy of the mid-19th century was discordant descriptions of the small scale structure of the solar surface. Visual observers contradicted each other by describing the surface as consisting of “corrugations”, “willow leaves”, “rice grains”, “cumuli”, “thatch”, “granules”, etc. Early photographs of the solar surface were not good enough to settle the controversy. The French astronomer Jules Janssen is credited with the first 1876 photographs that clearly showed what we now call solar granulation (1876, CRAS 82, 1363). Upon seeing these images, New Yorker Lewis M. Rutherfurd (1878, MNRAS 38, 410) praised the high quality of Janssen’s images but asserted that he had also photographed granulation as early as 1871 using collodion wet plates. He sent copies of his best photograph to the Royal Astronomical Society to support his assertion. Curious about his claim, Briggs and Harvey set up Rutherfurd’s 13-inch achromatic refractor on Kitt Peak and found that it easily showed well-resolved solar granulation, so his claim might well have been justified. But without his plates we could not confirm the claim. For 140 years the copies of Rutherfurd’s best solar photograph remained in the archives of the Royal Astronomical Society and were recently discovered by Prosser (RAS Photographs A3/001B and A3/002). By coincidence a few days later, Briggs found the original August 11, 1871 plate. Despite poor condition these photographs show solar granulation. There are at least two other possible early claimants (Reade; Vogel) but their plates are almost certainly lost. Rutherfurd was a master of astronomical instrumentation and photography. He was reticent about his work, letting results speak for themselves, so it is satisfying to find that he was justified in making his claim of priority.

  17. Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin

    Directory of Open Access Journals (Sweden)

    Sara eLawrence

    2012-11-01

    Full Text Available The cholesterol-dependent cytolysins (CDCs attack cells by punching large holes in their membranes. Lectinolysin from Streptococcus mitis is unique among CDCs due to the presence of an N-terminal lectin domain that enhances the pore-forming activity of the toxin. We recently determined the crystal structures of the lectin domain in complex with various glycans. These structures revealed the molecular basis for the Lewis antigen specificity of the toxin. Based on this information we have used in silico molecular modelling to design a mutant toxin, which we predicted would increase its specificity for Lewis y, an antigen found on the surface of cancer cells. Surprisingly, we found by surface plasmon resonance binding experiments that the resultant mutant lectin domain exhibited higher specificity for Lewis b antigens instead. We then undertook comparative crystallographic and molecular dynamics simulation studies of the wild-type and mutant lectin domains to understand the molecular basis for the disparity between the theoretical and experimental results. The crystallographic results revealed that the net number of interactions between Lewis y and wild-type versus mutant was unchanged whereas there was a loss of a hydrogen bond between mutant and Lewis b compared to wild-type. In contrast, the molecular dynamics studies revealed that the Lewis b antigen spent more time in the binding pocket of the mutant compared to wild-type and the reverse was true for Lewis y. The results of these simulation studies are consistent with the conclusions drawn from the surface plasmon resonance studies. This work is part of a program to engineer lectinolysin so that it will target and kill specific cells in human diseases.

  18. Analytically calculated post-Keplerian range and range-rate perturbations: the solar Lense-Thirring effect and BepiColombo

    Science.gov (United States)

    Iorio, Lorenzo

    2018-05-01

    We analytically calculate the time series for the perturbations Δ ρ \\left(t\\right), Δ \\dot{ρ }\\left(t\\right) induced by a general disturbing acceleration A on the mutual range ρ and range-rate \\dot{ρ } of two test particles A, B orbiting the same spinning body. We apply it to the general relativistic Lense-Thirring effect, due to the primary's spin S, and the classical perturbation arising from its quadrupole mass moment J2 for arbitrary orbital geometries and orientation of the source's symmetry axis {\\hat{S}}. The Earth-Mercury range and range-rate are nominally affected by the Sun's gravitomagnetic field to the 10 m, 10-3 cm s-1 level, respectively, during the extended phase (2026-2028) of the forthcoming BepiColombo mission to Mercury whose expected tracking accuracy is of the order of ≃0.1 m, 2 × 10-4 cm s-1. The competing signatures due to the solar quadrupole J_2^{\\odot }, if modelled at the σ _{J_2^{\\odot }}˜eq 10^{-9} level of the latest planetary ephemerides INPOP17a, are nearly 10 times smaller than the relativistic gravitomagnetic effects. The position and velocity vectors \\boldsymbol {r}, \\boldsymbol {v} of Mercury and Earth are changed by the solar Lense-Thirring effect by about 10 m, 1.5 m and 10-3 cm s-1, 10-5 cm s-1, respectively, over 2 yr; neglecting such shifts may have an impact on long-term integrations of the inner Solar system dynamics over ˜Gyr time-scales.

  19. Historical perspectives - The role of the NASA Lewis Research Center in the national space nuclear power programs

    Science.gov (United States)

    Bloomfield, H. S.; Sovie, R. J.

    1991-01-01

    The history of the NASA Lewis Research Center's role in space nuclear power programs is reviewed. Lewis has provided leadership in research, development, and the advancement of space power and propulsion systems. Lewis' pioneering efforts in nuclear reactor technology, shielding, high temperature materials, fluid dynamics, heat transfer, mechanical and direct energy conversion, high-energy propellants, electric propulsion and high performance rocket fuels and nozzles have led to significant technical and management roles in many natural space nuclear power and propulsion programs.

  20. Historical perspectives: The role of the NASA Lewis Research Center in the national space nuclear power programs

    Science.gov (United States)

    Bloomfield, H. S.; Sovie, R. J.

    1991-01-01

    The history of the NASA Lewis Research Center's role in space nuclear power programs is reviewed. Lewis has provided leadership in research, development, and the advancement of space power and propulsion systems. Lewis' pioneering efforts in nuclear reactor technology, shielding, high temperature materials, fluid dynamics, heat transfer, mechanical and direct energy conversion, high-energy propellants, electric propulsion and high performance rocket fuels and nozzles have led to significant technical and management roles in many national space nuclear power and propulsion programs.

  1. District heating from Forsmark

    International Nuclear Information System (INIS)

    1980-11-01

    The district heating system of Greater Stockholm must be based on other energy sources than oil. Two alternatives are assessed, namely heat from Forsmark or a coal fueled plant in the region of Stockholm. Forsmark 3 can produce both electricity and heat from the year 1988 on. The capacity can be increased by coal fueled blocks. For low electricity use, 115 TWh in the year 1990, the Forsmark alternative will be profitable. The alternative will be profitable. The alternative with a fossile fuelled plant will be profitable when planning for high consumption of electricity, 125 TWh. The Forsmark alternative means high investments and the introduction of new techniques. (G.B.)

  2. Stochastic Modeling of Rainfall in Peninsular Malaysia Using Bartlett Lewis Rectangular Pulses Models

    Directory of Open Access Journals (Sweden)

    Ibrahim Suliman Hanaish

    2011-01-01

    Full Text Available Three versions of Bartlett Lewis rectangular pulse rainfall models, namely, the Original Bartlett Lewis (OBL, Modified Bartlett Lewis (MBL, and 2N-cell-type Bartlett Lewis model (BL2n, are considered. These models are fitted to the hourly rainfall data from 1970 to 2008 obtained from Petaling Jaya rain gauge station, located in Peninsular Malaysia. The generalized method of moments is used to estimate the model parameters. Under this method, minimization of two different objective functions which involve different weight functions, one weight is inversely proportional to the variance and another one is inversely proportional to the mean squared, is carried out using Nelder-Mead optimization technique. For the purpose of comparison of the performance of the three different models, the results found for the months of July and November are used for illustration. This performance is assessed based on the goodness of fit of the models. In addition, the sensitivity of the parameter estimates to the choice of the objective function is also investigated. It is found that BL2n slightly outperforms OBL. However, the best model is the Modified Bartlett Lewis MBL, particularly when the objective function considered involves weight which is inversely proportional to the variance.

  3. The Streltsovskoye uranium district

    International Nuclear Information System (INIS)

    Ischukova, L.P.

    1997-01-01

    This paper describes the geology of the Streltsovskoye uranium district located in south-eastern Zabaikalie region, Chita Province, Siberia, Russia. This district hosts Russia's only currently active uranium production centre. The uranium ore was discovered from 1963 to 1967 by drilling below fluorite veins which had minor associated uranium mineralization and radioactive anomalies. The uranium occurs as large scale vein stockwork deposits of hydrothermal origin within a volcano-tectonic caldera formed by continental volcanism of Late Mesozoic age. Rocks occurring in the caldera include basalt and trachydacite, overlain by rhyolite, and with associated interbedded sediments. The ore bodies occur in steeply dipping faults, with the greatest concentrations located where faults along the margins of the caldera intersect steeply dipping, cross cutting, northeasterly and northwesterly striking faults. The Streltsovskoye caldera extends over an area of 150 km 2 and is underlain by a large batholith. The 19 identified uranium deposits occurred in structural features that cut through the caldera sequence and extend into the basement rocks. The caldera has a maximum thickness of 1400 metres. Details of several deposits are given, including descriptions of mineralization and associated alteration. (author). 10 figs

  4. Lewis-Acid/Base Effects on Gallium Volatility in Molten Chlorides

    International Nuclear Information System (INIS)

    Williams, D.F.

    2001-01-01

    It has been proposed that GaCl 3 can be removed by direct volatilization from a Pu-Ga alloy that is dissolved in a molten chloride salt. Although pure GaCl 3 is quite volatile (boiling point, 201 C), the behavior of GaCl 3 dissolved in chloride salts is different due to solution effects and is critically dependent on the composition of the solvent salt (i.e., its Lewis-acid/base character). In this report, the behavior of gallium in prototypical Lewis-acid and Lewis-base salts is compared. It was found that gallium volatility is suppressed in basic melts and enhanced in acidic melts. The implications of these results on the potential for simple gallium removal in molten salt systems are significant

  5. Composition, texture and methane potential of cellulosic residues from Lewis acids organosolv pulping of wheat straw.

    Science.gov (United States)

    Constant, Sandra; Barakat, Abdellatif; Robitzer, Mike; Di Renzo, Francesco; Dumas, Claire; Quignard, Françoise

    2016-09-01

    Cellulosic pulps have been successfully isolated from wheat straw through a Lewis acids organosolv treatment. The use of Lewis acids with different hardness produced pulps with different delignification degrees. The cellulosic residue was characterised by chemical composition, X-ray diffraction, FT-IR spectroscopy, N2 physisorption, scanning electron microscopy and potential for anaerobic digestibility. Surface area and pore volume increased with the hardness of the Lewis acid, in correspondence with the decrease of the amount of lignin and hemicellulose in the pulp. The non linearity of the correlation between porosity and composition suggests that an agglomeration of cellulose fibrils occurs in the early stages of pulping. All organosolv pulps presented a significantly higher methane potential than the parent straw. A methane evolution of 295Ncm(3)/g OM was reached by a moderate improvement of the accessibility of the native straw. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. A chromatographic study of the Lewis acid-base chemistry of zirconia surfaces

    International Nuclear Information System (INIS)

    Blackwell, J.A.; Carr, P.W.

    1991-01-01

    This paper reports on the chromatographic properties of porous microparticulate zirconium oxide surfaces in aqueous media which are highly dependent upon the chemical composition of the eluent. In particular, retention is controlled by the type and concentration of hard Ligand exchange is the dominant mechanism for the retention of solutes which are Lewis bases. consequently, the capacity factor and plate height depend on both the thermodynamic and kinetic properties of whatever competing Lewis bases may be present in the eluent. These Lewis base eluent components act to control retention in two ways. They modify the net ligand exchange contribution to retention, and they serve as sites for secondary interactions, such as hydrogen bonding and hydrophobic interactions between solutes and the dynamic stationary phase

  7. On the behaviour of biradicaloid [P(μ-NTer)]2 towards Lewis acids and bases.

    Science.gov (United States)

    Hinz, Alexander; Schulz, Axel; Villinger, Alexander

    2016-05-07

    The well-known diphosphadiazane-1,3-diyl [P(μ-NTer)]2 (Ter = 2,6-bis(2,4,6-trimethyl-phenyl)-phenyl) was treated with Lewis bases such as N-heterocyclic carbenes and Lewis acids e.g. gold(i) chloride complexes. In the reaction with the Lewis base, fragmentation of the P2N2 framework was observed, yielding a salt of the type [(NHC)2P](+)[(TerN)2P](-) in a clean reaction. The reaction of [P(μ-NTer)]2 with gold(i) chloride afforded 1 : 1 and 1 : 2 complexes. The dinuclear complex [(ClAu)2P(μ-NTer)2P] displays a bridging P atom between both gold centers, as has been observed for P based zwitterions.

  8. Lewis x is highly expressed in normal tissues: a comparative immunohistochemical study and literature revision.

    Science.gov (United States)

    Croce, María V; Isla-Larrain, Marina; Rabassa, Martín E; Demichelis, Sandra; Colussi, Andrea G; Crespo, Marina; Lacunza, Ezequiel; Segal-Eiras, Amada

    2007-01-01

    An immunohistochemical analysis was employed to determine the expression of carbohydrate antigens associated to mucins in normal epithelia. Tissue samples were obtained as biopsies from normal breast (18), colon (35) and oral cavity mucosa (8). The following carbohydrate epitopes were studied: sialyl-Lewis x, Lewis x, Lewis y, Tn hapten, sialyl-Tn and Thomsen-Friedenreich antigen. Mucins were also studied employing antibodies against MUC1, MUC2, MUC4, MUC5AC, MUC6 and also normal colonic glycolipid. Statistical analysis was performed and Kendall correlations were obtained. Lewis x showed an apical pattern mainly at plasma membrane, although cytoplasmic staining was also found in most samples. TF, Tn and sTn haptens were detected in few specimens, while sLewis x was found in oral mucosa and breast tissue. Also, normal breast expressed MUC1 at a high percentage, whereas MUC4 was observed in a small number of samples. Colon specimens mainly expressed MUC2 and MUC1, while most oral mucosa samples expressed MUC4 and MUC1. A positive correlation between MUC1VNTR and TF epitope (r=0.396) was found in breast samples, while in colon specimens MUC2 and colonic glycolipid versus Lewis x were statistically significantly correlated (r=0.28 and r=0.29, respectively). As a conclusion, a defined carbohydrate epitope expression is not exclusive of normal tissue or a determined localization, and it is possible to assume that different glycoproteins and glycolipids may be carriers of carbohydrate antigens depending on the tissue localization considered.

  9. Lewis Base Activation of Silyl Acetals: Iridium-Catalyzed Reductive Horner-Wadsworth-Emmons Olefination.

    Science.gov (United States)

    Dakarapu, Udaya Sree; Bokka, Apparao; Asgari, Parham; Trog, Gabriela; Hua, Yuanda; Nguyen, Hiep H; Rahman, Nawal; Jeon, Junha

    2015-12-04

    A Lewis base promoted deprotonative pronucleophile addition to silyl acetals has been developed and applied to the iridium-catalyzed reductive Horner-Wadsworth-Emmons (HWE) olefination of esters and the chemoselective reduction of the resulting enoates. Lewis base activation of silyl acetals generates putative pentacoordinate silicate acetals, which fragment into aldehydes, silanes, and alkoxides in situ. Subsequent deprotonative metalation of phosphonate esters followed by HWE with aldehydes furnishes enoates. This operationally convenient, mechanistically unique protocol converts the traditionally challenging aryl, alkenyl, and alkynyl esters to homologated enoates at room temperature within a single vessel.

  10. Anatomy of an organizational change effort at the Lewis Research Center

    Science.gov (United States)

    Hawker, James R.; Dali, Richard S.

    1988-01-01

    By 1979, after a long decline following the end of the Apollo program, the Lewis Research Center found its very existence endangered because it was not doing the kind of research that could attract funding at the time. New management under Andrew J. Stofan applied a program of strategic planning, participative management, and consensus decision making. A corporate-cultural change was effected which enabled Lewis to commit itself to four fundable research and development projects. Morale-building and training programs which were essential to this change are described.

  11. A Tale of Two Districts

    Science.gov (United States)

    Simon, Mark

    2012-01-01

    These days, everyone seems to be wringing their hands about how to construct new evaluation systems that will make teachers better. This unnecessary angst has led to crazy experiments in reform that have embraced churn for the sake of churn, put school districts at risk, and demoralized many of the most talented teachers. A few school districts,…

  12. Redesigning the District Operating System

    Science.gov (United States)

    Hodas, Steven

    2015-01-01

    In this paper, we look at the inner workings of a school district through the lens of the "district operating system (DOS)," a set of interlocking mutually-reinforcing modules that includes functions like procurement, contracting, data and IT policy, the general counsel's office, human resources, and the systems for employee and family…

  13. Suburban District Leadership Does Matter

    Science.gov (United States)

    Thompson, Eustace; France, Roxanne Garcia

    2015-01-01

    The increased demand for educational reform and accountability has resulted in a renewed focus on the relationship between building leaders and district leaders, particularly on how district leaders can support principals to ensure the academic success of students. The No Child Left Behind Act of 2001 (NCLB) and Race to the Top (RttT) legislations…

  14. NASA Lewis Launch Collision Probability Model Developed and Analyzed

    Science.gov (United States)

    Bollenbacher, Gary; Guptill, James D

    1999-01-01

    There are nearly 10,000 tracked objects orbiting the earth. These objects encompass manned objects, active and decommissioned satellites, spent rocket bodies, and debris. They range from a few centimeters across to the size of the MIR space station. Anytime a new satellite is launched, the launch vehicle with its payload attached passes through an area of space in which these objects orbit. Although the population density of these objects is low, there always is a small but finite probability of collision between the launch vehicle and one or more of these space objects. Even though the probability of collision is very low, for some payloads even this small risk is unacceptable. To mitigate the small risk of collision associated with launching at an arbitrary time within the daily launch window, NASA performs a prelaunch mission assurance Collision Avoidance Analysis (or COLA). For the COLA of the Cassini spacecraft, the NASA Lewis Research Center conducted an in-house development and analysis of a model for launch collision probability. The model allows a minimum clearance criteria to be used with the COLA analysis to ensure an acceptably low probability of collision. If, for any given liftoff time, the nominal launch vehicle trajectory would pass a space object with less than the minimum required clearance, launch would not be attempted at that time. The model assumes that the nominal positions of the orbiting objects and of the launch vehicle can be predicted as a function of time, and therefore, that any tracked object that comes within close proximity of the launch vehicle can be identified. For any such pair, these nominal positions can be used to calculate a nominal miss distance. The actual miss distances may differ substantially from the nominal miss distance, due, in part, to the statistical uncertainty of the knowledge of the objects positions. The model further assumes that these position uncertainties can be described with position covariance matrices

  15. Nuclear district heating

    International Nuclear Information System (INIS)

    Ricateau, P.

    1976-01-01

    An economic study of nuclear district heating is concerned with: heat production, its transmission towards the area to be served and the distribution management towards the consumers. Foreign and French assessments show that the high cost of now existing techniques of hot water transport defines the competing limit distance between the site and township to be below some fifty kilometers for the most important townships (provided that the fuel price remain stationary). All studies converge towards the choice of a high transport temperature as soon as the distance is of some twenty kilometers. As for fossile energy saving, some new possibilities appear with process heat reactors; either PWR of about 1000MWth for large townships, or pool-type reactors of about 100MWth when a combination with an industrial steam supply occurs [fr

  16. VT Data - Overlay District 20170710, South Burlington

    Data.gov (United States)

    Vermont Center for Geographic Information — Overlay data for the City of South Burlington included in this data:Flood Plain Overlay DistrictTraffic Overlay DistrictInterstate Highway Overlay DistrictScenic...

  17. VT Data - Overlay District 20170419, Colchester

    Data.gov (United States)

    Vermont Center for Geographic Information — The following Overlay Districts are included in the data:General Development Four Commercial DistrictGeneral Development Four Openspace DistrictShoreland...

  18. A systematic revision of Baconia Lewis (Coleoptera, Histeridae, Exosternini

    Directory of Open Access Journals (Sweden)

    Michael Caterino

    2013-10-01

    Full Text Available Here we present a complete revision of the species of Baconia. Up until now there have been 27 species assigned to the genus (Mazur, 2011, in two subgenera (Binhister Cooman and Baconia s. str., with species in the Neotropical, Nearctic, Palaearctic, and Oriental regions. We recognize all these species as valid and correctly assigned to the genus, and redescribe all of them. We synonymize Binhister, previously used for a polyphyletic assemblage of species with varied relationships in the genus. We move four species into Baconia from other genera, and describe 85 species as new, bringing the total for the genus to 116 species. We divide these into 12 informal species groups, leaving 13 species unplaced to group. We present keys and diagnoses for all species, as well as habitus photos and illustrations of male genitalia for nearly all. The genus now contains the following species and species groups: Baconia loricata group [B. loricata Lewis, 1885, B. patula Lewis, 1885, B. gounellei (Marseul, 1887a, B. jubaris (Lewis, 1901, B. festiva (Lewis, 1891, B. foliosoma sp. n., B. sapphirina sp. n., B. furtiva sp. n., B. pernix sp. n., B. applanatis sp. n., B. disciformis sp. n., B. nebulosa sp. n., B. brunnea sp. n.], B. godmani group [B. godmani (Lewis, 1888, B. venusta (J. E. LeConte, 1845, B. riehli (Marseul, 1862, comb. n., B. scintillans sp. n., B. isthmia sp. n., B. rossi sp. n., B. navarretei sp. n., B. maculata sp. n., B. deliberata sp. n., B. excelsa sp. n., B. violacea (Marseul, 1853, B. varicolor (Marseul, 1887b, B. dives (Marseul, 1862, B. eximia (Lewis, 1888, B. splendida sp. n., B. jacinta sp. n., B. prasina sp. n., B. opulenta sp. n., B. illustris (Lewis, 1900, B. choaspites (Lewis, 1901, B. lewisi Mazur, 1984], B. salobrus group [B. salobrus (Marseul, 1887b, B. turgifrons sp. n., B. crassa sp. n., B. anthracina sp. n., B. emarginata sp. n., B. obsoleta sp. n.], B. ruficauda group [B. ruficauda sp. n., B. repens sp. n.], B. angusta group [B

  19. A systematic revision of Baconia Lewis (Coleoptera, Histeridae, Exosternini).

    Science.gov (United States)

    Caterino, Michael S; Tishechkin, Alexey K

    2013-01-01

    Here we present a complete revision of the species of Baconia. Up until now there have been 27 species assigned to the genus (Mazur, 2011), in two subgenera (Binhister Cooman and Baconia s. str.), with species in the Neotropical, Nearctic, Palaearctic, and Oriental regions. We recognize all these species as valid and correctly assigned to the genus, and redescribe all of them. We synonymize Binhister, previously used for a polyphyletic assemblage of species with varied relationships in the genus. We move four species into Baconia from other genera, and describe 85 species as new, bringing the total for the genus to 116 species. We divide these into 12 informal species groups, leaving 13 species unplaced to group. We present keys and diagnoses for all species, as well as habitus photos and illustrations of male genitalia for nearly all. The genus now contains the following species and species groups: Baconia loricata group [Baconia loricata Lewis, 1885, B. patula Lewis, 1885, Baconia gounellei (Marseul, 1887a), Baconia jubaris (Lewis, 1901), Baconia festiva (Lewis, 1891), Baconia foliosoma sp. n., Baconia sapphirina sp. n., Baconia furtiva sp. n., Baconia pernix sp. n., Baconia applanatis sp. n., Baconia disciformis sp. n., Baconia nebulosa sp. n., Baconia brunnea sp. n.], Baconia godmani group [Baconia godmani (Lewis, 1888), Baconia venusta (J. E. LeConte, 1845), Baconia riehli (Marseul, 1862), comb. n., Baconia scintillans sp. n., Baconia isthmia sp. n., Baconia rossi sp. n., Baconia navarretei sp. n., Baconia maculata sp. n., Baconia deliberata sp. n., Baconia excelsa sp. n., Baconia violacea (Marseul, 1853), Baconia varicolor (Marseul, 1887b), Baconia dives (Marseul, 1862), Baconia eximia (Lewis, 1888), Baconia splendida sp. n., Baconia jacinta sp. n., Baconia prasina sp. n., Baconia opulenta sp. n., Baconia illustris (Lewis, 1900), Baconia choaspites (Lewis, 1901), Baconia lewisi Mazur, 1984], Baconia salobrus group [Baconia salobrus (Marseul, 1887b), Baconia

  20. VT Data - Overlay District 20070306, Marlboro

    Data.gov (United States)

    Vermont Center for Geographic Information — Cartographic version of overlay district (surface water buffer), Marlboro, Vermont. Base zoning districts are in a separate shapefile. Data were originally created...

  1. Land application of mine water causes minimal uranium loss offsite in the wet-dry tropics: Ranger Uranium Mine, Northern Territory, Australia

    International Nuclear Information System (INIS)

    Mumtaz, Saqib; Streten, Claire; Parry, David L.; McGuinness, Keith A.; Lu, Ping; Gibb, Karen S.

    2015-01-01

    Ranger Uranium Mine (RUM) is situated in the wet-dry tropics of Northern Australia. Land application (irrigation) of stockpile (ore and waste) runoff water to natural woodland on the mine lease is a key part of water management at the mine. Consequently, the soil in these Land Application Areas (LAAs) presents a range of uranium (U) and other metals concentrations. Knowledge of seasonal and temporal changes in soil U and physicochemical parameters at RUM LAAs is important to develop suitable management and rehabilitation strategies. Therefore, soil samples were collected from low, medium, high and very high U sites at RUM LAAs for two consecutive years and the effect of time and season on soil physicochemical parameters particularly U and other major solutes applied in irrigation water was measured. Concentrations of some of the solutes applied in the irrigation water such as sulphur (S), iron (Fe) and calcium (Ca) showed significant seasonal and temporal changes. Soil S, Fe and Ca concentration decreased from year 1 to year 2 and from dry to wet seasons during both years. Soil U followed the same pattern except that we recorded an increase in soil U concentrations at most of the RUM LAAs after year 2 wet season compared to year 2 dry season. Thus, these sites did not show a considerable decrease in soil U concentration from year 1 to year 2. Sites which contained elevated U after wet season 2 also had higher moisture content which suggests that pooling of U containing rainwater at these sites may be responsible for elevated U. Thus, U may be redistributed within RUM LAAs due to surface water movement. The study also suggested that a decrease in U concentrations in LAA soils at very high U (>900 mg kg"−"1) sites is most likely due to transport of particulate matter bound U by surface runoff and U may not be lost from the surface soil due to vertical movement through the soil profile. Uranium attached to particulate matter may reduce its potential for

  2. Anion sensing with a Lewis acidic BODIPY-antimony(v) derivative.

    Science.gov (United States)

    Christianson, Anna M; Gabbaï, François P

    2017-02-21

    We describe the synthesis of a BODIPY dye substituted with a Lewis acidic antimony(v) moiety. This compound, which has been fully characterized, shows a high affinity for small anions including fluoride and cyanide, the complexation of which elicits a fluorescence turn-on response.

  3. Compensatory shifts in visual perception are associated with hallucinations in Lewy body disorders.

    Science.gov (United States)

    Bowman, Alan Robert; Bruce, Vicki; Colbourn, Christopher J; Collerton, Daniel

    2017-01-01

    Visual hallucinations are a common, distressing, and disabling symptom of Lewy body and other diseases. Current models suggest that interactions in internal cognitive processes generate hallucinations. However, these neglect external factors. Pareidolic illusions are an experimental analogue of hallucinations. They are easily induced in Lewy body disease, have similar content to spontaneous hallucinations, and respond to cholinesterase inhibitors in the same way. We used a primed pareidolia task with hallucinating participants with Lewy body disorders (n = 16), non-hallucinating participants with Lewy body disorders (n = 19), and healthy controls (n = 20). Participants were presented with visual "noise" that sometimes contained degraded visual objects and were required to indicate what they saw. Some perceptions were cued in advance by a visual prime. Results showed that hallucinating participants were impaired in discerning visual signals from noise, with a relaxed criterion threshold for perception compared to both other groups. After the presentation of a visual prime, the criterion was comparable to the other groups. The results suggest that participants with hallucinations compensate for perceptual deficits by relaxing perceptual criteria, at a cost of seeing things that are not there, and that visual cues regularize perception. This latter finding may provide a mechanism for understanding the interaction between environments and hallucinations.

  4. Dorothy L. Sayers and C. S. Lewis: Christian Postmodernism beyond Boundaries

    Science.gov (United States)

    Yuasa, Kyoko

    2012-01-01

    Modern critics do not consider science fiction and mystery novels to be "serious reading", but Dorothy L. Sayers and C. S. Lewis questioned the boundaries between "popular" and "serious" literature. Both Christian writers critically discuss the spiritual crisis of the modern world in each fiction genre. This paper…

  5. Lewis Nkosi: A Fragile Soul's Quest for Home | Gall | English in Africa

    African Journals Online (AJOL)

    Lewis Nkosi left South Africa in 1961 on a permanent exit visa on his way to study at Harvard as a Nieman Fellow. During his seventy-three years, he lived in England, America, Zambia, Poland, and Switzerland, and he transitioned from denying homesickness (because he had no home) to feeling it acutely (because he had ...

  6. Curcumin reduces trabecular and cortical bone in naive and Lewis lung carcinoma-bearing mice

    Science.gov (United States)

    The present study investigated the effects of dietary supplementation with curcumin on bone microstructural changes in female C57BL/6 mice in the presence or absence of Lewis lung carcinoma. Morphometric analysis showed that in tumor-bearing mice curcumin at 2% and 4% dietary levels (w/w) significa...

  7. Effect of induced hyperglycemia on metastatic spreading in Lewis lung carcinoma

    International Nuclear Information System (INIS)

    Shmakova, N.L.; Fomenkova, T.E.; Fadeeva, T.A.

    1991-01-01

    The effect of induced hyperglycemia on the intensity of metastatic dissemination of Lewis lung carcinoma was investigated in experiments on mice. Neither long-, nor short-term hyperglycemia, induced at different phases of dissemination, influenced the intensity of metastatic spreading, primary tumor growth, the time of appearance of metastases, and the average life duration of tumor-bearing animals

  8. Daniel Day-Lewis lihvis Oscari-rolli neli aastat / Triin Tael

    Index Scriptorium Estoniae

    Tael, Triin

    2008-01-01

    Paul Thomas Andersoni Upton Sinclairi "Õli" järgi lavastatud "Veri hakkab voolama" ("There Will Be Blood"), peaosas Daniel Day-Lewis : Ameerika Ühendriigid 2007. Näitleja võitis oma rolliga parima meespeaosatäitja Oscari. Tema tööst rolli(de)ga

  9. Lewis Acid-Base Properties of a Low Carbon Aluminium Killed Steel ...

    African Journals Online (AJOL)

    An important factor in achieving maximum adhesion of a particular coating system to the substrate lies in the proper preparation of the substrate prior to the application of paint. The Lewis acid-base properties of the outer metal surface play a determinant role in many of these applications, and the chemical reactions involved ...

  10. Providing Total Quality Fundamentals: 1995 Workshops for the NASA Lewis Research Center's Technical Services Directorate

    Science.gov (United States)

    Antczak, Paul; Jacinto,Gilda; Simek, Jimmy

    1997-01-01

    The National Aeronautics and Space Administration's (NASA) agency-wide movement to cultivate a quality workplace is the basis for Lewis Research Center to implement Total Quality Fundamentals (TQF) initiatives. The Lewis Technical Services Directorate (TSD) introduced the Total Quality Fundamentals (TQF) workshops to its work force as an opportunity to introduce the concepts and principles of TQF. These workshops also provided the participants with the opportunity to dialogue with fellow TSD employees and managers. This report describes, through the perspective of the Lewis TSD TQF Coaches, how the TQF work- shop process was accomplished in TSD. It describes the structure for addressing the need, implementation process, input the TSD Coaches provided, common themes and concerns raised, conclusions, and recommendations. The Coaches concluded that these types of workshops could be the key to open the communication channels that are necessary to help everyone at Lewis understand where they fit in the organization. TQF workshops can strengthen the participant's connection with the Mission, Vision of the Center, and Vision of the Agency. Reconunendations are given based on these conclusions that can help the TSD Quality Board develop attainable measures towards a quality workplace.

  11. Lewis-acid catalyzed depolymerization of Protobind lignin in supercritical water and ethanol

    NARCIS (Netherlands)

    Güvenatam, B.; Heeres, E.H.J.; Pidko, E.A.; Hensen, E.J.M.

    2014-01-01

    The use of metal acetates, metal chlorides and metal triflates as Lewis acid catalysts for the depolymerization of soda lignin under supercritical conditions was investigated. The reactions were carried out at 400°C in water and ethanol. Lignin conversion in supercritical water led to formation of

  12. Lewis-acid catalyzed depolymerization of Protobind lignin in supercritical water and ethanol

    NARCIS (Netherlands)

    Guvenatam, Burcu; Heeres, Erik H.J.; Pidko, Evgeny A.; Hensen, Ernie J. M.

    2016-01-01

    The use of metal acetates, metal chlorides and metal triflates as Lewis acid catalysts for the depolymerization of soda lignin under supercritical conditions was investigated. The reactions were carried out at 400 degrees C in water and ethanol. Lignin conversion in supercritical water led to

  13. The Brainstem Pathologies of Parkinson's Disease and Dementia with Lewy Bodies

    NARCIS (Netherlands)

    Seidel, Kay; Mahlke, Josefine; Siswanto, Sonny; Krueger, Reijko; Heinsen, Helmut; Auburger, Georg; Bouzrou, Mohamed; Grinberg, Lea T.; Wicht, Helmut; Korf, Horst-Werner; den Dunnen, Wilfred; Rueb, Udo

    Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are among the human synucleinopathies, which show alpha-synuclein immunoreactive neuronal and/or glial aggregations and progressive neuronal loss in selected brain regions (eg, substantia nigra, ventral tegmental area, pedunculopontine

  14. Navy John Lewis (TAO 205) Class Oiler Shipbuilding Program: Background and Issues for Congress

    Science.gov (United States)

    2016-08-18

    These wires are placed under tension to support fuel hoses for refueling operations or trolleys that move pallets of provisions, ammunition, or other...SECNAV Mabus Names First TAO(X) Next Generation Oiler After Rep. John Lewis,” USNI News, January 6, 2016. 6 Sam LaGrone, “Navy to Name Ship After Gay

  15. Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson's Disease-like Dementia

    DEFF Research Database (Denmark)

    Ejlerskov, Patrick; Hultberg, Jeanette Göransdotter; Wang, JunYang

    2015-01-01

    -causing mutant proteins. Mice lacking Ifnb function exhibited motor and cognitive learning impairments with accompanying α-synuclein-containing Lewy bodies in the brain, as well as a reduction in dopaminergic neurons and defective dopamine signaling in the nigrostriatal region. Lack of IFN-β signaling caused...

  16. Life on the Fringe: The Early Writings of Lewis Nkosi and Nat Nakasa1

    African Journals Online (AJOL)

    One evening in the late 1950s, Lewis Nkosi and his friend Nat Nakasa were walking through downtown Johannesburg when, as both later recalled, they decided to stop into a whites-only restaurant called The Texan. They ordered their coffees at the bar, knowing that the American man behind the counter expected them to ...

  17. Solid State Technology Branch of NASA Lewis Research Center: Fifth Annual Digest

    International Nuclear Information System (INIS)

    1993-08-01

    The digest is a collection of papers written by the members of the Solid State Technology Branch of NASA Lewis Research Center from June 1992-June 1993. The papers cover a range of topics relating to superconductivity, monolithic microwave integrated circuits (MMIC's), coplanar waveguide, and material characterization. Individual papers are abstracted separately on the data base

  18. Paradise Lost and Found: Obedience, Disobedience, and Storytelling in C.S. Lewis and Philip Pullman.

    Science.gov (United States)

    Wood, Naomi

    2001-01-01

    Considers how in the fantasy series "The Chronicles of Narnia" and "His Dark Materials," by C.S. Lewis and Philip Pullman respectively, the authors use symbols and themes from "Paradise Lost." Notes that each author's narrative choice uses his view of cosmic order to persuade readers that obedience should be…

  19. David Lewis in the Lab: Experimental Results on the Emergence of Meaning

    NARCIS (Netherlands)

    Bruner, Justin; O'Connor, Cailin; Rubin, Hannah; Huttegger, S. (Simon)

    2014-01-01

    In this paper we use an experimental approach to investigate how linguistic conventions can emerge in a society without explicit agreement. As a starting point we consider the signaling game introduced by Lewis (Convention 1969). We find that in experimental settings, small groups can quickly

  20. α-Synuclein pathology in the cranial and spinal nerves in Lewy body disease.

    Science.gov (United States)

    Nakamura, Keiko; Mori, Fumiaki; Tanji, Kunikazu; Miki, Yasuo; Toyoshima, Yasuko; Kakita, Akiyoshi; Takahashi, Hitoshi; Yamada, Masahito; Wakabayashi, Koichi

    2016-06-01

    Accumulation of phosphorylated α-synuclein in neurons and glial cells is a histological hallmark of Lewy body disease (LBD) and multiple system atrophy (MSA). Recently, filamentous aggregations of phosphorylated α-synuclein have been reported in the cytoplasm of Schwann cells, but not in axons, in the peripheral nervous system in MSA, mainly in the cranial and spinal nerve roots. Here we conducted an immunohistochemical investigation of the cranial and spinal nerves and dorsal root ganglia of patients with LBD. Lewy axons were found in the oculomotor, trigeminal and glossopharyngeal-vagus nerves, but not in the hypoglossal nerve. The glossopharyngeal-vagus nerves were most frequently affected, with involvement in all of 20 subjects. In the spinal nerve roots, Lewy axons were found in all of the cases examined. Lewy axons in the anterior nerves were more frequent and numerous in the thoracic and sacral segments than in the cervical and lumbar segments. On the other hand, axonal lesions in the posterior spinal nerve roots appeared to increase along a cervical-to-sacral gradient. Although Schwann cell cytoplasmic inclusions were found in the spinal nerves, they were only minimal. In the dorsal root ganglia, axonal lesions were seldom evident. These findings indicate that α-synuclein pathology in the peripheral nerves is axonal-predominant in LBD, whereas it is restricted to glial cells in MSA. © 2015 Japanese Society of Neuropathology.

  1. Stress and Burden among Caregivers of Patients with Lewy Body Dementia

    Science.gov (United States)

    Leggett, Amanda N.; Zarit, Steven; Taylor, Angela; Galvin, James E.

    2011-01-01

    Purpose: Patients with Lewy body dementia (LBD) may present a unique set of symptoms and challenges to family caregivers compared with other types of dementia. Prominent difficulties include motor impairment, activities of daily living (ADLs) disability, recurrent behavioral and emotional problems (BEPs), and diagnostic difficulties. These…

  2. Random forest to differentiate dementia with Lewy bodies from Alzheimer's disease

    NARCIS (Netherlands)

    Dauwan, Meenakshi; van der Zande, Jessica J.; van Dellen, Edwin; Sommer, Iris E C; Scheltens, Philip; Lemstra, Afina W.; Stam, Cornelis J.

    2016-01-01

    Introduction The aim of this study was to build a random forest classifier to improve the diagnostic accuracy in differentiating dementia with Lewy bodies (DLB) from Alzheimer's disease (AD) and to quantify the relevance of multimodal diagnostic measures, with a focus on electroencephalography

  3. 2006 Southwest Florida Water Management District (SWFWMD) Lidar: North District

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is one component of a digital terrain model (DTM) for the Southwest Florida Water Management District's FY2006 Digital Orthophoto (B089) and LiDAR...

  4. Allegheny County School District Boundaries

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — This dataset demarcates the school district boundaries within Allegheny County If viewing this description on the Western Pennsylvania Regional Data Center’s open...

  5. New Mexico Property Tax Districts

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This layer represents boundaries for New Mexico tax district "OUT" categories and incorporated/municipal "IN" categories as identified on the "Certificate of Tax...

  6. The Winfrith district gamma survey

    International Nuclear Information System (INIS)

    Cavell, I.W.; Peabody, C.O.

    1961-09-01

    This report describes the District Gamma Survey carried out around the A.E.E., Winfrith since June, 1959. Its organisation, equipment and techniques are described, and the results obtained up to the 31st December, 1960 are given. (author)

  7. Boise geothermal district heating system

    Energy Technology Data Exchange (ETDEWEB)

    Hanson, P.J.

    1985-10-01

    This document describes the Boise geothermal district heating project from preliminary feasibility studies completed in 1979 to a fully operational system by 1983. The report includes information about the two local governments that participated in the project - the City of Boise, Idaho and the Boise Warm Springs Water District. It also discusses the federal funding sources; the financial studies; the feasibility studies conducted; the general system planning and design; design of detailed system components; the legal issues involved in production; geological analysis of the resource area; distribution and disposal; the program to market system services; and the methods of retrofitting buildings to use geothermal hot water for space heating. Technically this report describes the Boise City district heating system based on 170/sup 0/F water, a 4000 gpm production system, a 41,000 foot pipeline system, and system economies. Comparable data are also provided for the Boise Warm Springs Water District. 62 figs., 31 tabs.

  8. Adsorption properties of the soils of the Ranger uranium mine land application area for solutes in water from Retention Pond 2

    International Nuclear Information System (INIS)

    Willett, I.R.; Bond, W.J.

    1992-01-01

    The research reported here aimed to describe the adsorption properties of the soils of Ranger's irrigation area for important constituents of RP2 water. Three kinds of experiments were conducted. For the major ions (Na + , Mg 2+ , Ca 2+ , K + , SO 4 2-, and Cl - ) measurements were made of cation and anion exchange capacities. For the minor solutes (MN 2+ , U 238 , and Ra 226 ) which undergo more specific, inner-sphere reactions with soil surfaces, the retention capacities were determined by batch adsorption isotherm methods. Lastly, column experiments were conducted to determine whether the soils could retain U 238 , Ra 226 and Pb 210 when the quantities of each radionuclide were applied in much greater quantities than was possible in the batch adsorption studies, or during the field experiment described earlier at this Workshop (Bond and Willett 1992). It was aimed to obtain information on the retention capacity of the three main soil types of the irrigation area; Unit I, II and III, respectively red earths, yellow earths and siliceous sands, in relation to soil pH. 7 refs., 4 tabs., 13 figs

  9. 76 FR 17105 - Sitka Resource Advisory Committee

    Science.gov (United States)

    2011-03-28

    ... to Lisa Hirsch, Sitka Ranger District, 204 Siginaka Way, Sitka, Alaska 99835. Comments may also be... FURTHER INFORMATION CONTACT: Lisa Hirsch, RAC coordinator, USDA, Tongass NF, Sitka Ranger District, 204...

  10. Building new discrete supramolecular assemblies through the interaction of iso-tellurazole N-oxides with Lewis acids and bases.

    Science.gov (United States)

    Ho, Peter C; Jenkins, Hilary A; Britten, James F; Vargas-Baca, Ignacio

    2017-10-13

    The supramolecular macrocycles spontaneously assembled by iso-tellurazole N-oxides are stable towards Lewis bases as strong as N-heterocyclic carbenes (NHC) but readily react with Lewis acids such as BR 3 (R = Ph, F). The electron acceptor ability of the tellurium atom is greatly enhanced in the resulting O-bonded adducts, which consequently enables binding to a variety of Lewis bases that includes acetonitrile, 4-dimethylaminopyridine, 4,4'-bipyridine, triphenyl phosphine, a N-heterocyclic carbene and a second molecule of iso-tellurazole N-oxide.

  11. An order in Lewy body disorders: Retrograde degeneration in hyperbranching axons as a fundamental structural template accounting for focal/multifocal Lewy body disease.

    Science.gov (United States)

    Uchihara, Toshiki

    2017-04-01

    Initial clinical recognition of "paralysis agitans" by James Parkinson was expanded by Jean-Martin Charcot, who recognized additional clinical findings of his own, such as slowness (distinct from paralysis), rigidity (distinct from spasticity) and characteristic countenance. Charcot assembled these findings under the umbrella of "Parkinson disease (PD)". This purely clinical concept was so prescient and penetrating that subsequent neuropathological and biochemical evidences were ordered along this axis to establish the nigra-central trinity of PD (dopamine depletion, nigral lesion with Lewy bodies: LBs). Although dramatic efficacy of levodopa boosted an enthusiasm for this nigra-centralism, extranigral lesions were identified, especially after identification of alpha-synuclein (αS) as a major constituent of LBs. Frequent αS lesions in the lower brainstem with their presumed upward spread were coupled with the self-propagating property of αS molecule, as a molecular template, to constitute the prion-Braak hypothesis. This hybrid concept might expectedly explain clinical, structural and biochemical features of PD/dementia with Lewy bodies (DLB) as if they were stereotypic. In spite of this ordered explanation, recent studies have demonstrated unexpectedly that αS lesions in the human brain, as well as their corresponding clinical manifestations, are much more disordered. Even with such a chaos of LB disorders, affected neuronal groups are uniformly characterized by hyperbranching axons, which may facilitate distal-dominant degeneration and retrograde progression of LB-related degeneration along axons as a fundamental structural order to template LB disorders. This "structural template" hypothesis may explain why: (i) some selective groups are prone to develop Lewy pathology; (ii) their clinical manifestations (especially non-motor components) are vague and generalized without somatotopic accentuation; (iii) distal axons and terminals are preferentially affected

  12. District Governance and Student Learning in Indonesia

    OpenAIRE

    Pradhan, Menno; de Ree, Joppe

    2014-01-01

    We document the likely importance of district governance and teacher management policies in relation to student learning in Indonesian primary schools. As the responsibility to deliver primary education has been decentralized to district governments, we expect district specific variations in teacher management policies. Consequently, we also expect variations in learning trajectories across districts. We document substantial heterogeneity in learning gains across districts. Furthermore, we sh...

  13. ɑ-Synuclein strains and seeding in Parkinson's disease, incidental Lewy body disease, dementia with Lewy bodies and multiple system atrophy: similarities and differences.

    Science.gov (United States)

    Peelaerts, W; Bousset, L; Baekelandt, V; Melki, R

    2018-04-27

    Several age-related neurodegenerative disorders are characterized by the deposition of aberrantly folded endogenous proteins. These proteins have prion-like propagation and amplification properties but so far appear nontransmissible between individuals. Because of the features they share with the prion protein, PrP, the characteristics of pathogenic protein aggregates in several progressive brain disorders, including different types of Lewy body diseases (LBDs), such as Parkinson's disease (PD), multiple system atrophy (MSA) and dementia with Lewy bodies (DLB), have been actively investigated. Even though the pleomorphic nature of these syndromes might suggest different underlying causes, ɑ-synuclein (ɑSyn) appears to play an important role in this heterogeneous group of diseases (the synucleinopathies). An attractive hypothesis is that different types of ɑSyn protein assemblies have a unique and causative role in distinct synucleinopathies. We will discuss the recent research progress on ɑSyn assemblies involved in PD, MSA and DLB; their behavior as strains; current spreading hypotheses; their ability to seed centrally and peripherally; and their implication for disease pathogenesis.

  14. Brush Polymer of Donor-Accepter Dyads via Adduct Formation between Lewis Base Polymer Donor and All Carbon Lewis Acid Acceptor

    Directory of Open Access Journals (Sweden)

    Yang Wang

    2017-09-01

    Full Text Available A synthetic method that taps into the facile Lewis base (LB→Lewis acid (LA adduct forming reaction between the semiconducting polymeric LB and all carbon LA C60 for the construction of covalently linked donor-acceptor dyads and brush polymer of dyads is reported. The polymeric LB is built on poly(3-hexylthiophene (P3HT macromers containing either an alkyl or vinyl imidazolium end group that can be readily converted into the N-heterocyclic carbene (NHC LB site, while the brush polymer architecture is conveniently constructed via radical polymerization of the macromer P3HT with the vinyl imidazolium chain end. Simply mixing of such donor polymeric LB with C60 rapidly creates linked P3HT-C60 dyads and brush polymer of dyads in which C60 is covalently linked to the NHC junction connecting the vinyl polymer main chain and the brush P3HT side chains. Thermal behaviors, electronic absorption and emission properties of the resulting P3HT-C60 dyads and brush polymer of dyads have been investigated. The results show that a change of the topology of the P3HT-C60 dyad from linear to brush architecture enhances the crystallinity and Tm of the P3HT domain and, along with other findings, they indicate that the brush polymer architecture of donor-acceptor domains provides a promising approach to improve performances of polymer-based solar cells.

  15. NASA Lewis Helps Company With New Single-Engine Business Turbojet

    Science.gov (United States)

    1998-01-01

    Century Aerospace Corporation, a small company in Albuquerque, New Mexico, is developing a six-seat aircraft powered by a single turbofan engine for general aviation. The company had completed a preliminary design of the jet but needed analyses and testing to proceed with detailed design and subsequent fabrication of a prototype aircraft. NASA Lewis Research Center used computational fluid dynamics (CFD) analyses to ferret out areas of excessive curvature in the inlet where separation might occur. A preliminary look at the results indicated very good inlet performance; and additional calculations, performed with vortex generators installed in the inlet, led to even better results. When it was initially determined that the airflow distortion pattern at the compressor face fell outside of the limits set by the engine manufacturer, the Lewis team studied possible solutions, selected the best, and provided recommendations. CFD results for the inlet system were so good that wind tunnel tests were unnecessary.

  16. Elk Monitoring Protocol for Lewis and Clark National Historical Park, Version 1.0

    Science.gov (United States)

    Jenkins, Kurt J.; Griffin, Paul C.; Boetsch, John R.; Cole, Carla

    2011-01-01

    Maintaining elk (Cervus elaphus roosevelti) herds that frequent Lewis and Clark National Historical Park (NHP) is central to the park’s purpose of preserving the historic, cultural, scenic, and natural resources. Elk were critical to sustaining the members of the Lewis and Clark expedition by providing food and clothing over the winter of 1805-1806. Today, elk viewing opportunities in the park and surrounding region generate broad appeal with the visiting public, which number over 250,000 per year at the Fort Clatsop visitor center. This protocol describes procedures for monitoring trends in the use of the Fort Clatsop area by Roosevelt elk. Specific objectives of elk monitoring in Lewis and Clark NHP are to measure the relative use and proportion of area used by elk during winter in the Fort Clatsop Unit of the park, and the rate at which elk are sighted from roads in and around the park. Relative use and the proportion of area used by elk are determined from elk fecal pellet surveys conducted every other year in the Fort Clatsop park unit. Pairs of observers visit a systematic array of permanent plots in the fall to clear them of elk fecal pellets, and return to the plots in late winter to count elk fecal pellets that have accumulated during winter. Half of the subplots are counted by two independent observers, which allows for the estimation of relative use and proportion of area occupied by elk with analyses of detection biases that account for unseen elk pellet groups. Standardized road surveys are conducted in and near the Fort Clatsop park unit three or four times monthly during alternate months. Data from road surveys are used to quantify the rate that park visitors would be expected to see elk, when driving the selected set of routes. The monitoring protocol is based on three field seasons of development and testing. The protocol narrative describes the background, rationale, sampling design, field methods, analytical methods, data management, reporting

  17. Gallium-containing polymer brush film as efficient supported Lewis acid catalyst in a glass microreactor

    Directory of Open Access Journals (Sweden)

    Rajesh Munirathinam

    2013-08-01

    Full Text Available Polystyrene sulfonate polymer brushes, grown on the interior of the microchannels in a microreactor, have been used for the anchoring of gallium as a Lewis acid catalyst. Initially, gallium-containing polymer brushes were grown on a flat silicon oxide surface and were characterized by FTIR, ellipsometry, and X-ray photoelectron spectroscopy (XPS. XPS revealed the presence of one gallium per 2–3 styrene sulfonate groups of the polymer brushes. The catalytic activity of the Lewis acid-functionalized brushes in a microreactor was demonstrated for the dehydration of oximes, using cinnamaldehyde oxime as a model substrate, and for the formation of oxazoles by ring closure of ortho-hydroxy oximes. The catalytic activity of the microreactor could be maintained by periodic reactivation by treatment with GaCl3.

  18. Applied high-speed imaging for the icing research program at NASA Lewis Research Center

    Science.gov (United States)

    Slater, Howard; Owens, Jay; Shin, Jaiwon

    1992-01-01

    The Icing Research Tunnel at NASA Lewis Research Center provides scientists a scaled, controlled environment to simulate natural icing events. The closed-loop, low speed, refrigerated wind tunnel offers the experimental capability to test for icing certification requirements, analytical model validation and calibration techniques, cloud physics instrumentation refinement, advanced ice protection systems, and rotorcraft icing methodology development. The test procedures for these objectives all require a high degree of visual documentation, both in real-time data acquisition and post-test image processing. Information is provided to scientific, technical, and industrial imaging specialists as well as to research personnel about the high-speed and conventional imaging systems will be on the recent ice protection technology program. Various imaging examples for some of the tests are presented. Additional imaging examples are available from the NASA Lewis Research Center's Photographic and Printing Branch.

  19. Autoinduced catalysis and inverse equilibrium isotope effect in the frustrated Lewis pair catalyzed hydrogenation of imines.

    Science.gov (United States)

    Tussing, Sebastian; Greb, Lutz; Tamke, Sergej; Schirmer, Birgitta; Muhle-Goll, Claudia; Luy, Burkhard; Paradies, Jan

    2015-05-26

    The frustrated Lewis pair (FLP)-catalyzed hydrogenation and deuteration of N-benzylidene-tert-butylamine (2) was kinetically investigated by using the three boranes B(C6F5)3 (1), B(2,4,6-F3-C6H2)3 (4), and B(2,6-F2-C6H3)3 (5) and the free activation energies for the H2 activation by FLP were determined. Reactions catalyzed by the weaker Lewis acids 4 and 5 displayed autoinductive catalysis arising from a higher free activation energy (2 kcal mol(-1)) for the H2 activation by the imine compared to the amine. Surprisingly, the imine reduction using D2 proceeded with higher rates. This phenomenon is unprecedented for FLP and resulted from a primary inverse equilibrium isotope effect. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. System Critical Design Audit (CDA). Books 1, 2 and 3; [Small Satellite Technology Initiative (SSTI Lewis Spacecraft Program)

    Science.gov (United States)

    1995-01-01

    Small Satellite Technology Initiative (SSTI) Lewis Spacecraft Program is evaluated. Spacecraft integration, test, launch, and spacecraft bus are discussed. Payloads and technology demonstrations are presented. Mission data management system and ground segment are also addressed.

  1. 76 FR 30937 - Environmental Impacts Statements; Notice of Availability

    Science.gov (United States)

    2011-05-27

    ... and to Areas within and Adjacent to Wildland Urban Interface near Tennant, Goosenest Ranger District... land Use Development in the Specific Plan Area, City of Folsom, Sacramento County, CA, Review Period... 2004 FEIS, Ashland Ranger District, Rogue River National Forest and Scott River Ranger District...

  2. Intermolecular interactions of trifluorohalomethanes with Lewis bases in the gas phase: an ab initio study.

    Science.gov (United States)

    Wang, Yi-Siang; Yin, Chih-Chien; Chao, Sheng D

    2014-10-07

    We perform an ab initio computational study of molecular complexes with the general formula CF3X-B that involve one trifluorohalomethane CF3X (X = Cl or Br) and one of a series of Lewis bases B in the gas phase. The Lewis bases are so chosen that they provide a range of electron-donating abilities for comparison. Based on the characteristics of their electron pairs, we consider the Lewis bases with a single n-pair (NH3 and PH3), two n-pairs (H2O and H2S), two n-pairs with an unsaturated bond (H2CO and H2CS), and a single π-pair (C2H4) and two π-pairs (C2H2). The aim is to systematically investigate the influence of the electron pair characteristics and the central atom substitution effects on the geometries and energetics of the formed complexes. The counterpoise-corrected supermolecule MP2 and coupled-cluster single double with perturbative triple [CCSD(T)] levels of theory have been employed, together with a series of basis sets up to aug-cc-pVTZ. The angular and radial configurations, the binding energies, and the electrostatic potentials of the stable complexes have been compared and discussed as the Lewis base varies. For those complexes where halogen bonding plays a significant role, the calculated geometries and energetics are consistent with the σ-hole model. Upon formation of stable complexes, the C-X bond lengths shorten, while the C-X vibrational frequencies increase, thus rendering blueshifting halogen bonds. The central atom substitution usually enlarges the intermolecular bond distances while it reduces the net charge transfers, thus weakening the bond strengths. The analysis based on the σ-hole model is grossly reliable but requires suitable modifications incorporating the central atom substitution effects, in particular, when interaction components other than electrostatic contributions are involved.

  3. Sustainable Materials Replacement for Prevention of Corrosion at Fort Lewis, WA

    Science.gov (United States)

    2009-08-01

    documents a building reclamation project at Fort Lewis, WA, in which significant portions of the work were completed using market -available sustainable...contractors to submit previous technology performance or test documentation, which is generally published as products are introduced to the market . If...evaluate the performance of the E2C2 in its final configuration. Energy use will be analyzed using a Building Infor- mation Model ( BIM ) to simulate

  4. Humour in the Game of Kings: The Sideways Glancing Warder of the Lewis Chessmen

    OpenAIRE

    Hüsing, Annika

    2014-01-01

    The cultural turn of the twentieth century’s last quarter gradually led to a new approach to the classical objects of historical research. Historians nowadays are required to take on a 'cultural perspective' in the course of their studies. Using the example of a particular piece of the Lewis Chessmen this paper examines both the benefits and the limitations that come about with the cultural approach and cautions against a too rigid application.

  5. Fibre type composition of soleus and extensor digitorum longus muscles in normal female inbred Lewis rats

    Czech Academy of Sciences Publication Activity Database

    Soukup, Tomáš; Zachařová, Gisela; Smerdu, V.

    2002-01-01

    Roč. 104, č. 4 (2002), s. 399-405 ISSN 0065-1281 R&D Projects: GA ČR GA304/00/1653 Grant - others:CZ - SI Czech-Slovenian Intergovernmental S&T Co-operation(XC) - Institutional research plan: CEZ:AV0Z5011922 Keywords : inbred Lewis rats * skeletal muscles * soleus and EDL muscles Subject RIV: FH - Neurology Impact factor: 0.867, year: 2002

  6. Energy efficiency campaign for residential housing at the Fort Lewis army installation

    Energy Technology Data Exchange (ETDEWEB)

    AH McMakin; RE Lundgren; EL Malone

    2000-02-23

    In FY1999, Pacific Northwest National Laboratory conducted an energy efficiency campaign for residential housing at the Fort Lewis Army Installation near Tacoma, Washington. Preliminary weather-corrected calculations show energy savings of 10{percent} from FY98 for energy use in family housing. This exceeded the project's goal of 3{percent}. The work was funded by the U.S. DOEs Federal Energy Management Program (FEMP), Office of Energy Efficiency and Renewable Energy. The project adapted FEMP's national ``You Have the Power Campaign'' at the local level, tailoring it to the military culture. The applied research project was designed to demonstrate the feasibility of tailored, research-based strategies to promote energy conservation in military family housing. In contrast to many energy efficiency efforts, the campaign focused entirely on actions residents could take in their own homes, as opposed to technology or housing upgrades. Behavioral change was targeted because residents do not pay their own utility bills; thus other motivations must drive personal energy conservation. This campaign augments ongoing energy savings from housing upgrades carried out by Fort Lewis. The campaign ran from September 1998 through August 1999. The campaign strategy was developed based on findings from previous research and on input from residents and officials at Fort Lewis. Energy use, corrected to account for weather differences, was compared with the previous year's use. Survey responses from 377 of Fort Lewis residents of occupied housing showed that the campaign was moderately effective in promoting behavior change. Of those who were aware of the campaign, almost all said they were now doing one or more energy-efficient things that they had not done before. Most people were motivated by the desire to do the right thing and to set a good example for their children. They were less motivated by other factors.

  7. Vasoprotective effects of life span-extending peripubertal GH replacement in Lewis dwarf rats.

    Science.gov (United States)

    Ungvari, Zoltan; Gautam, Tripti; Koncz, Peter; Henthorn, Jim C; Pinto, John T; Ballabh, Praveen; Yan, Han; Mitschelen, Matthew; Farley, Julie; Sonntag, William E; Csiszar, Anna

    2010-11-01

    In humans, growth hormone deficiency (GHD) and low circulating levels of insulin-like growth factor 1 (IGF-1) significantly increase the risk for cerebrovascular disease. Genetic growth hormone (GH)/IGF-1 deficiency in Lewis dwarf rats significantly increases the incidence of late-life strokes, similar to the effects of GHD in elderly humans. Peripubertal treatment of Lewis dwarf rats with GH delays the occurrence of late-life stroke, which results in a significant extension of life span. The present study was designed to characterize the vascular effects of life span-extending peripubertal GH replacement in Lewis dwarf rats. Here, we report, based on measurements of dihydroethidium fluorescence, tissue isoprostane, GSH, and ascorbate content, that peripubertal GH/IGF-1 deficiency in Lewis dwarf rats increases vascular oxidative stress, which is prevented by GH replacement. Peripubertal GHD did not alter superoxide dismutase or catalase activities in the aorta nor the expression of Cu-Zn-SOD, Mn-SOD, and catalase in the cerebral arteries of dwarf rats. In contrast, cerebrovascular expression of glutathione peroxidase 1 was significantly decreased in dwarf vessels, and this effect was reversed by GH treatment. Peripubertal GHD significantly decreases expression of the Nrf2 target genes NQO1 and GCLC in the cerebral arteries, whereas it does not affect expression and activity of endothelial nitric oxide synthase and vascular expression of IGF-1, IGF-binding proteins, and inflammatory markers (tumor necrosis factor alpha, interluekin-6, interluekin-1β, inducible nitric oxide synthase, intercellular adhesion molecule 1, and monocyte chemotactic protein-1). In conclusion, peripubertal GH/IGF-1 deficiency confers pro-oxidative cellular effects, which likely promote an adverse functional and structural phenotype in the vasculature, and results in accelerated vascular impairments later in life.

  8. Divergent functional connectivity during attentional processing in Lewy body dementia and Alzheimer's disease

    OpenAIRE

    Kobeleva, Xenia; Firbank, Michael; Peraza, Luis; Gallagher, Peter; Thomas, Alan; Burn, David J.; O'Brien, John; Taylor, John-Paul

    2017-01-01

    Attention and executive dysfunction are features of Lewy body dementia (LBD) but their neuroanatomical basis is poorly understood. To investigate underlying dysfunctional attention-executive network (EXEC) interactions, we examined functional connectivity (FC) in 30 patients with LBD, 20 patients with Alzheimer's disease (AD), and 21 healthy controls during an event-related functional magnetic resonance imaging (fMRI) experiment. Participants performed a modified Attention Network Test (ANT),...

  9. Technology requirements to be addressed by the NASA Lewis Research Center Cryogenic Fluid Management Facility program

    Science.gov (United States)

    Aydelott, J. C.; Rudland, R. S.

    1985-01-01

    The NASA Lewis Research Center is responsible for the planning and execution of a scientific program which will provide advance in space cryogenic fluid management technology. A number of future space missions were identified that require or could benefit from this technology. These fluid management technology needs were prioritized and a shuttle attached reuseable test bed, the cryogenic fluid management facility (CFMF), is being designed to provide the experimental data necessary for the technology development effort.

  10. Effects of the immunomodulator, VGX-1027, in endotoxin-induced uveitis in Lewis rats

    DEFF Research Database (Denmark)

    Mangano, K; Sardesai, N Y; Quattrocchi, C

    2008-01-01

    VGX-1027 is a novel, low molecular weight, immunomodulatory compound that has shown efficacy against a variety of immuno-inflammatory disease models in animals including autoimmune diabetes in NOD mice, collagen-induced arthritis and chemically induced inflammatory colitis. Here, we have studied ...... the effects of VGX-1027 on the development of endotoxin-induced uveitis (EIU) in male Lewis rats, as a model of inflammatory ocular diseases in humans....

  11. Regionalization of the Modified Bartlett-Lewis Rectangular Pulse Stochastic Rainfall Model

    OpenAIRE

    Dongkyun Kim; Francisco Olivera; Huidae Cho; Scott A. Socolofsky

    2013-01-01

    Parameters of the Modified Bartlett-Lewis Rectangular Pulse (MBLRP) stochastic rainfall simulation model were regionalized across the contiguous United States. Three thousand four hundred forty-four National Climate Data Center (NCDC) rain gauges were used to obtain spatial and seasonal patterns of the model parameters. The MBLRP model was calibrated to minimize the discrepancy between the precipitation depth statistics between the observed and MBLRP-generated precipitation time series. These...

  12. Lewis base catalyzed enantioselective allylic hydroxylation of Morita-Baylis-Hillman carbonates with water

    KAUST Repository

    Zhu, Bo

    2011-08-19

    A Lewis base catalyzed allylic hydroxylation of Morita-Baylis-Hillman (MBH) carbonates has been developed. Various chiral MBH alcohols can be synthesized in high yields (up to 99%) and excellent enantioselectivities (up to 94% ee). This is the first report using water as a nucleophile in asymmetric organocatalysis. The nucleophilic role of water has been verified using 18O-labeling experiments. © 2011 American Chemical Society.

  13. Borax in the supraglacial moraine of the Lewis Cliff, Buckley Island quadrangle--first Antarctic occurrence

    Science.gov (United States)

    Fitzpatrick, J.J.; Muhs, D.R.

    1989-01-01

    During the 1987-1988 austral summer field season, membersof the south party of the antarctic search for meteorites south-ern team* working in the Lewis Cliff/Colbert Hills region dis-covered several areas of unusual mineralization within theLewis Cliff ice tongue and its associated moraine field (figure1). The Lewis Cliff ice tongue (84°15'S 161°25'E) is a meteorite-stranding surface of ablating blue ice, about 2.3 by 7.0 kilo-meters, bounded on the west by the Lewis Cliff, on the northand northeast by a large supraglacial moraine, and on the eastby the Colbert Hills. To the south it opens to the Walcott Névé.Because it is a meteorite-stranding surface, the major component of ice motion in the area is believed to be vertical(Whillans and Cassidy 1983). The presence of Thule-Baffinmoraines at the northern terminus of the blue ice tends tosupport the hypothesis that the area underlying the moraineis essentially stagnant and that ice arriving from the south ispiling up against it. Areas containing mineral deposits werefound within the moraine field to the north and east of theblue ice margin and also along the east margins of the blue iceitself. Subsequent X-ray diffraction analyses of these depositshave shown that they are composed predominantly of nah-colite (NaHCO3), trona [Na3(CO3)(HCO3) · 2H20], borax[Na2B405(OH)4 · 8H20], and a new hexagonal hydrous sulfatespecies. This paper reports the details of the borax occurrence,because it is the first known on the continent.

  14. Terrestrial ages of ordinary chondrites from the lewis cliff stranding area, East Antarctica

    Science.gov (United States)

    Welten, K. C.; Lindner, L.; Alderliesten, C.; van der Borg, K.

    1999-07-01

    We determined terrestrial ages of ordinary chondrites from the Lewis Cliff stranding area, East Antarctica, on the basis of the concentrations of cosmogenic 10Be (t1/2 = 1.51 Ma), 26Al (t1/2 = 0.705 Ma) and 36Cl (t1/2 = 0.301 Ma). After an initial 26Al -ray survey of 91 meteorites suggested that many have terrestrial ages larger than 0.1 Ma, we selected 62 meteorites for 10Be and 26Al measurements by accelerator mass spectrometry (AMS) and measured 36Cl in twelve of those. Low terrestrial ages (Ma) were found for about 60% of the meteorites, whereas all others have ages between 0.1 and 0.5 Ma, except for one exceptional age of >2 Ma (Welten et al., 1997). Our major conclusions are: (1) The Lewis Cliff H-chondrites show similar ages as those from the Allan Hills Ice-fields, but the L-chondrites are about a factor of two younger than those from Allan Hills, which indicates that Lewis Cliff is a younger stranding area. (2) The terrestrial age distributions at different parts of the Lewis Cliff stranding area generally agree with simple meteorite concentration models, although differences in weathering rate may also play a role. (3) We confirm that meteorites with natural thermoluminescence (TL) levels >80 krad are associated with low terrestrial ages (Benoit et al., 1992), but conclude that natural TL levels <80 krad can not be used to calculate the terrestrial age of a meteorite. Natural TL levels do seem useful to estimate relative terrestrial ages of large groups of meteorites and to determine differences in surface exposure age of paired meteorite fragments. (4) Of the 62 meteorites measured with AMS, 31 were assigned to eleven different pairing groups, mainly on the basis of their cosmogenic nuclide record. The meteorites are estimated to represent between 42 and 52 distinct falls.

  15. Lewis acid tuned facial stereodivergent HDA reactions using beta-substituted N-vinyloxazolidinones.

    Science.gov (United States)

    Gohier, Frédéric; Bouhadjera, Keltoum; Faye, Djibril; Gaulon, Catherine; Maisonneuve, Vincent; Dujardin, Gilles; Dhal, Robert

    2007-01-18

    The [4 + 2] acido-catalyzed heterocycloaddition between new beta-substituted N-vinyl-1,3-oxazolidin-2-ones (with R' = Me, Ar, CH2 Ar) and beta,gamma-unsaturated alpha-ketoesters (R = Ar) afforded heteroadducts with high levels of endo and facial selectivities. A complete reversal of facial differentiation was achieved by varying the Lewis acid, leading to the stereoselective formation of either endo-alpha or endo-beta adducts. [reaction: see text].

  16. Applied Analytical Combustion/emissions Research at the NASA Lewis Research Center - a Progress Report

    Science.gov (United States)

    Deur, J. M.; Kundu, K. P.; Nguyen, H. L.

    1992-01-01

    Emissions of pollutants from future commercial transports are a significant concern. As a result, the Lewis Research Center (LeRC) is investigating various low emission combustor technologies. As part of this effort, a combustor analysis code development program was pursued to guide the combustor design process, to identify concepts having the greatest promise, and to optimize them at the lowest cost in the minimum time.

  17. Applied analytical combustion/emissions research at the NASA Lewis Research Center

    Science.gov (United States)

    Deur, J. M.; Kundu, K. P.; Nguyen, H. L.

    1992-01-01

    Emissions of pollutants from future commercial transports are a significant concern. As a result, the Lewis Research Center (LeRC) is investigating various low emission combustor technologies. As part of this effort, a combustor analysis code development program was pursued to guide the combustor design process, to identify concepts having the greatest promise, and to optimize them at the lowest cost in the minimum time.

  18. Synthesis, characterization, and application of two Al(OR(F))3 Lewis superacids.

    Science.gov (United States)

    Kraft, Anne; Trapp, Nils; Himmel, Daniel; Böhrer, Hannes; Schlüter, Peter; Scherer, Harald; Krossing, Ingo

    2012-07-23

    We report herein the synthesis and full characterization of the donor-free Lewis superacids Al(OR(F))(3) with OR(F) = OC(CF(3))(3) (1) and OC(C(5)F(10))C(6)F(5) (2), the stabilization of 1 as adducts with the very weak Lewis bases PhF, 1,2-F(2)C(6)H(4), and SO(2), as well as the internal C-F activation pathway of 1 leading to Al(2)(F)(OR(F))(5) (4) and trimeric [FAl(OR(F))(2)](3) (5, OR(F) = OC(CF(3))(3)). Insights have been gained from NMR studies, single-crystal structure determinations, and DFT calculations. The usefulness of these Lewis acids for halide abstractions has been demonstrated by reactions with trityl chloride (NMR; crystal structures). The trityl salts allow the introduction of new, heteroleptic weakly coordinating [Cl-Al(OR(F))(3)](-) anions, for example, by hydride or alkyl abstraction reactions. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Surface functionalization of two-dimensional metal chalcogenides by Lewis acid-base chemistry

    Science.gov (United States)

    Lei, Sidong; Wang, Xifan; Li, Bo; Kang, Jiahao; He, Yongmin; George, Antony; Ge, Liehui; Gong, Yongji; Dong, Pei; Jin, Zehua; Brunetto, Gustavo; Chen, Weibing; Lin, Zuan-Tao; Baines, Robert; Galvão, Douglas S.; Lou, Jun; Barrera, Enrique; Banerjee, Kaustav; Vajtai, Robert; Ajayan, Pulickel

    2016-05-01

    Precise control of the electronic surface states of two-dimensional (2D) materials could improve their versatility and widen their applicability in electronics and sensing. To this end, chemical surface functionalization has been used to adjust the electronic properties of 2D materials. So far, however, chemical functionalization has relied on lattice defects and physisorption methods that inevitably modify the topological characteristics of the atomic layers. Here we make use of the lone pair electrons found in most of 2D metal chalcogenides and report a functionalization method via a Lewis acid-base reaction that does not alter the host structure. Atomic layers of n-type InSe react with Ti4+ to form planar p-type [Ti4+n(InSe)] coordination complexes. Using this strategy, we fabricate planar p-n junctions on 2D InSe with improved rectification and photovoltaic properties, without requiring heterostructure growth procedures or device fabrication processes. We also show that this functionalization approach works with other Lewis acids (such as B3+, Al3+ and Sn4+) and can be applied to other 2D materials (for example MoS2, MoSe2). Finally, we show that it is possible to use Lewis acid-base chemistry as a bridge to connect molecules to 2D atomic layers and fabricate a proof-of-principle dye-sensitized photosensing device.

  20. Visual cortex in dementia with Lewy bodies: magnetic resonance imaging study

    Science.gov (United States)

    Taylor, John-Paul; Firbank, Michael J.; He, Jiabao; Barnett, Nicola; Pearce, Sarah; Livingstone, Anthea; Vuong, Quoc; McKeith, Ian G.; O’Brien, John T.

    2012-01-01

    Background Visual hallucinations and visuoperceptual deficits are common in dementia with Lewy bodies, suggesting that cortical visual function may be abnormal. Aims To investigate: (1) cortical visual function using functional magnetic resonance imaging (fMRI); and (2) the nature and severity of perfusion deficits in visual areas using arterial spin labelling (ASL)-MRI. Method In total, 17 participants with dementia with Lewy bodies (DLB group) and 19 similarly aged controls were presented with simple visual stimuli (checkerboard, moving dots, and objects) during fMRI and subsequently underwent ASL-MRI (DLB group n = 15, control group n = 19). Results Functional activations were evident in visual areas in both the DLB and control groups in response to checkerboard and objects stimuli but reduced visual area V5/MT (middle temporal) activation occurred in the DLB group in response to motion stimuli. Posterior cortical perfusion deficits occurred in the DLB group, particularly in higher visual areas. Conclusions Higher visual areas, particularly occipito-parietal, appear abnormal in dementia with Lewy bodies, while there is a preservation of function in lower visual areas (V1 and V2/3). PMID:22500014

  1. Application and optimization of input parameter spaces in mass flow modelling: a case study with r.randomwalk and r.ranger

    Science.gov (United States)

    Krenn, Julia; Zangerl, Christian; Mergili, Martin

    2017-04-01

    r.randomwalk is a GIS-based, multi-functional, conceptual open source model application for forward and backward analyses of the propagation of mass flows. It relies on a set of empirically derived, uncertain input parameters. In contrast to many other tools, r.randomwalk accepts input parameter ranges (or, in case of two or more parameters, spaces) in order to directly account for these uncertainties. Parameter spaces represent a possibility to withdraw from discrete input values which in most cases are likely to be off target. r.randomwalk automatically performs multiple calculations with various parameter combinations in a given parameter space, resulting in the impact indicator index (III) which denotes the fraction of parameter value combinations predicting an impact on a given pixel. Still, there is a need to constrain the parameter space used for a certain process type or magnitude prior to performing forward calculations. This can be done by optimizing the parameter space in terms of bringing the model results in line with well-documented past events. As most existing parameter optimization algorithms are designed for discrete values rather than for ranges or spaces, the necessity for a new and innovative technique arises. The present study aims at developing such a technique and at applying it to derive guiding parameter spaces for the forward calculation of rock avalanches through back-calculation of multiple events. In order to automatize the work flow we have designed r.ranger, an optimization and sensitivity analysis tool for parameter spaces which can be directly coupled to r.randomwalk. With r.ranger we apply a nested approach where the total value range of each parameter is divided into various levels of subranges. All possible combinations of subranges of all parameters are tested for the performance of the associated pattern of III. Performance indicators are the area under the ROC curve (AUROC) and the factor of conservativeness (FoC). This

  2. Efficient Lewis Acid Ionic Liquid-Catalyzed Synthesis of the Key Intermediate of Coenzyme Q10 under Microwave Irradiation

    Directory of Open Access Journals (Sweden)

    Thomas Efferth

    2010-12-01

    Full Text Available An efficient synthesis of a valuable intermediate of coenzyme Q10 by microwave-assisted Lewis acidic ionic liquid (IL-catalyzed Friedel-Crafts alkylation is reported. The acidity of six [Etpy]BF4-based ionic liquids was characterized by means of the FT-IR technique using acetonitrile as a molecular probe. The catalytic activities of these ionic liquids were correlated with their Lewis acidity. With increasing Lewis acid strength of the ionic liquids, their catalytic activity in the Friedel-Crafts reaction increased, except for [Etpy]BF4-AlCl3. The effects of the reaction system, the molar fraction of Lewis acid in the Lewis acid ILs and heating techniques were also investigated. Among the six Lewis acid ionic liquids tested [Etpy]BF4-ZnCl2 showed the best catalytic activity, with a yield of 89% after a very short reaction time (150 seconds. This procedure has the advantages of higher efficiency, better reusability of ILs, energy conservation and eco-friendliness. The method has practical value for preparation of CoQ10 on an industrial scale.

  3. Case report of Lewy body disease mimicking Creutzfeldt-Jakob disease in a 44-year-old man.

    Science.gov (United States)

    Saint-Aubert, Laure; Pariente, Jérémie; Dumas, Herve; Payoux, Pierre; Brandel, Jean-Philippe; Puel, Michèle; Vital, Anne; Guedj, Eric; Lesage, Suzanne; Peoc'h, Katell; Brefel Courbon, Christine; Ory Magne, Fabienne

    2016-07-30

    Few patients are reported with dementia with Lewy bodies before fifty years-old, which may partly reflect the difficulty of accurate diagnosis in young population. We report the case of a 44-year-old male with pathologically confirmed sporadic dementia with Lewy bodies, who did not fulfil the revised clinical criteria for this disease. We document this atypical case with clinical and cognitive evaluation, imaging, biochemistry, genetics and pathology investigations. Creutzfeldt-Jakob disease was first suspected in this patient with no previous medical history, who developed acute and rapid cognitive impairment, L-dopa-non-responsive parkinsonism, and delusion. Positive 14-3-3 protein was initially detected in cerebrospinal fluid and until the late stages of the disease. Severe atrophy with no diffusion hypersignal was found on structural MRI as well as an extensive hypometabolism on (18)F-FDG-PET, in comparison to age-matched healthy volunteers. Genetic investigation found no alpha-synuclein gene mutation. The patient died within 5 years, and post-mortem examination found numerous Lewy bodies and Lewy neurites consistent with pure Lewy body disease. This comprehensively described case illustrates that dementia with Lewy bodies can occur in young patients with atypical clinical presentation. Biochemistry and neuroimaging investigations can sometimes be insufficient to allow accurate diagnostic. More specific markers to support such diagnosis are needed.

  4. Industrial District as a Corporation

    Directory of Open Access Journals (Sweden)

    Reza MOHAMMADY GARFAMY

    2011-03-01

    Full Text Available This paper provides a comparison study of industrial districts in two European countries, Spain and Sweden, using the conceptual framework of corporation. The relevance of this approach is based on the specific qualities that the industrial districts have, including the preexisting conditions, local traditions, products and production characteristics, marketing strategies, local policies and present challenges. The findings indicate the ways in which different patterns of inter-firm relationships, organization of production and dynamics of local alliances have shaped divergent regional responses to the industrial construction.

  5. Improving district heating in Kiev

    International Nuclear Information System (INIS)

    Salminen, P.

    2000-01-01

    The district heating modernisation project currently under way in Kiev, the capital of the Ukraine, is the largest project of its type financed by the World Bank. The budget for the five-year project is some USD 250 million of which USD 200 million is financed by the World Bank loan. The target of the project is to improve the city's district heating system, which is owned and operated by Kyivenergo. Consultancy services for the Project Implementation Unit are being provided by Electrowatt-Ekono and financed by the Finnish government

  6. Future Services for District Heating Solutions in Residential Districts

    Directory of Open Access Journals (Sweden)

    Hannele Ahvenniemi

    2014-06-01

    Full Text Available The underlying assumption of this study is that in order to retain the competitiveness while reaching for the EU targets regarding low-energy construction, district heating companies need to develop new business and service models. How district heating companies could broaden their perspective and switch to a more service-oriented way of thinking is a key interest of our research. The used methods in our study are house builder interviews and a questionnaire. With the help of these methods we discussed the potential interest in heating related services acquiring a comprehensive understanding of the customer needs. The results indicate the importance of certain criteria when choosing the heating system in households: easiness, comfort and affordability seem to dominate the house builders’ preferences. Also environmental awareness seems to be for many an important factor when making a decision about the heating of the house. Altogether, based on the results of this study, we suggest that the prospects of district heating could benefit from highlighting certain aspects and strengths in the future. District heating companies need to increase flexibility, readiness to adopt new services, to invest in new marketing strategies and improving the communication skills.

  7. Freqüências relativas dos fenótipos eritrocitários ABO e Lewis na doença de Jorge Lobo Frequencies of ABO and Lewis blood groups in Jorge Lobo's disease

    Directory of Open Access Journals (Sweden)

    Eliane A. Silva

    2004-03-01

    Full Text Available A doença de Jorge Lobo é uma micose de evolução crônica, causada pelo Lacazia loboi. Os mecanismos envolvidos na suscetibilidade/resistência do hospedeiro frente ao agente não estão ainda elucidados, dentre eles encontra-se a constituição genética. Portanto, o objetivo deste trabalho é avaliar a distribuição dos grupos sangüíneos ABO e Lewis de pacientes com doença de Jorge Lobo em relação à população geral. Foram analisados 13 pacientes provenientes do estado do Acre, 60 indivíduos da região de Bauru (SP não acometidos pela doença em estudo (grupo controle Lewis e 2.673 doadores do Banco de Sangue da cidade de Rio Branco (AC como grupo controle ABO. As presenças dos antígenos eritrocitários foram determinadas pela reação de aglutinação em tubo através dos soros anti-AB, anti-A e anti-B para o fenótipo ABO e dos soros anti-Lewis a e Lewis b para fenotipagem Lewis. As freqüências fenotípicas Lewis e ABO nos pacientes e nos controles são, respectivamente: Le (a- b+ = 54,0% X 72,0%, Le (a+ b- = 15,0% X 6,0%, Le (a- b- = 31,0% X 22,0% ; A =15,4% X 33,6%, B = 30,8% X 10,8%, O = 53,8% X 52,9%, AB = 0 X 2,7%. Embora não tenhamos encontrado resultados estatisticamente significantes, nossos achados sugerem existir suscetibilidade à doença de Jorge Lobo em indivíduos com fenótipo B e com menor freqüência fenotípica Lewis b, conferindo assim um grau de importância epidemiológica como grupo de risco naquele meio ambiente.Jorge Lobo's disease is a mycosis with chronic evolution caused by the fungus Lacazia loboi. The mechanisms involved in host resistance and susceptibility to the agent, including aspects relating to the genetic background, are still not clear. The objective of the present study, therefore, is to evaluate the ABO and Lewis blood group distributions in Jorge Lobo's disease patients compared to the general population. Thirteen patients from Acre state, 60 healthy individuals (Lewis control group

  8. Lewis Acid Pairs for the Activation of Biomass-derived Oxygenates in Aqueous Media

    Energy Technology Data Exchange (ETDEWEB)

    Roman, Yuriy [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

    2015-09-14

    The objective of this project is to understand the mechanistic aspects behind the cooperative activation of oxygenates by catalytic pairs in aqueous media. Specifically, we will investigate how the reactivity of a solid Lewis acid can be modulated by pairing the active site with other catalytic sites at the molecular level, with the ultimate goal of enhancing activation of targeted functional groups. Although unusual catalytic properties have been attributed to the cooperative effects promoted by such catalytic pairs, virtually no studies exist detailing the use heterogeneous water-tolerant Lewis pairs. A main goal of this work is to devise rational pathways for the synthesis of porous heterogeneous catalysts featuring isolated Lewis pairs that are active in the transformation of biomass-derived oxygenates in the presence of bulk water. Achieving this technical goal will require closely linking advanced synthesis techniques; detailed kinetic and mechanistic investigations; strict thermodynamic arguments; and comprehensive characterization studies of both materials and reaction intermediates. For the last performance period (2014-2015), two technical aims were pursued: 1) C-C coupling using Lewis acid and base pairs in Lewis acidic zeolites. Tin-, zirconium-, and hafnium containing zeolites (e.g., Sn-, Zr-, and Hf-Beta) are versatile solid Lewis acids that selectively activate carbonyl functional groups. In this aim, we demonstrate that these zeolites catalyze the cross-aldol condensation of aromatic aldehydes with acetone under mild reaction conditions with near quantitative yields. NMR studies with isotopically labeled molecules confirm that acid-base pairs in the Si-O-M framework ensemble promote soft enolization through α-proton abstraction. The Lewis acidic zeolites maintain activity in the presence of water and, unlike traditional base catalysts, in acidic solutions. 2) One-pot synthesis of MWW zeolite nanosheets for activation of bulky substrates. Through

  9. Districts Neglecting Programs for ELLs

    Science.gov (United States)

    Zehr, Mary Ann

    2010-01-01

    The author reports on state and independent reviews that cite shortcomings in four urban systems. According to the reviews of those school systems over the past two years, four urban districts--in Boston, Massachusetts; Buffalo, New York; Portland, Oregon; and Seattle, Washington--did not provide special help to learn English to all students…

  10. Nation, Districts Step up Safety

    Science.gov (United States)

    Shah, Nirvi

    2013-01-01

    President Barack Obama's announcement last week of a wide-ranging anti-violence plan in response to the Newtown, Connecticut, school shootings comes as many districts are adopting new and sometimes dramatic measures--including arming teachers and volunteers--intended to prevent similar tragedies in their own schools. School safety experts warn…

  11. Marketing Techniques for School Districts.

    Science.gov (United States)

    Lane, John J., Ed.

    Development of marketing plans can assist not only public school districts in meeting recent competition but will also improve educational processes, increase revenue, and restore confidence in schools. This collection of articles describes a new role for school administrators--particulary for business managers: administrators as "entrepreneurs."…

  12. Location - Managed Facility - St. Paul District (MVP)

    Data.gov (United States)

    Army Corps of Engineers, Department of the Army, Department of Defense — St. Paul District - US Army Corps of Engineers Managed Facility locations. District headquarters, Natural Resource, Recreation, Lock and Dam, and Regulatory offices...

  13. U.S. Coast Guard (USCG) Districts

    Data.gov (United States)

    Department of Homeland Security — This layer is a polygonal dataset that represents land and maritime boundaries for each representative United States Coast Guard district, which includes district 1,...

  14. VT Data - Overlay District 20170228, Richmond

    Data.gov (United States)

    Vermont Center for Geographic Information — The following overlay districts are included in the data:Shoreline Protection OverlayFlood Hazard OverlayDetails about these overlay districts, as well as zoning...

  15. Reading a District Budget: Reporter Guide

    Science.gov (United States)

    McNeil, Michele

    2013-01-01

    Every school budget tells a story--about a district's spending plan, its priorities, goals, and financial health. The challenge is to wade through the jargon and numbers to unlock that story. Although budgets can vary significantly from district to district, and state to state, this primer seeks to introduce reporters to the fundamental components…

  16. 7 CFR 958.27 - Districts.

    Science.gov (United States)

    2010-01-01

    ...; (2) changes in the relative position of existing districts with respect to onion production; (3) the... and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE ONIONS GROWN IN CERTAIN DESIGNATED... Districts. (a) For the purpose of selecting committee members, the following districts of the production...

  17. Sexual Harassment Policies in Florida School Districts.

    Science.gov (United States)

    Rienzo, Barbara A.; Moore, Michele Johnson

    1998-01-01

    Investigated the extent to which Florida's school districts complied with the Florida Department of Education's (FDOE) recommendations for addressing sexual harassment in schools. Surveys of district equity coordinators and analysis of policies indicated that most districts approved sexual harassment policies incorporating many FDOE…

  18. School District Cash Management. Program Audit.

    Science.gov (United States)

    New York State Legislative Commission on Expenditure Review, Albany.

    New York State law permits school districts to invest cash not immediately needed for district operation and also specifies the kinds of investments that may be made in order to ensure the safety and liquidity of public funds. This audit examines cash management and investment practices in New York state's financially independent school districts.…

  19. 7 CFR 982.31 - Grower districts.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Grower districts. 982.31 Section 982.31 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... importance of production in each district and the number of growers in each district; (2) the geographic...

  20. Conflict Management in Declining School Districts.

    Science.gov (United States)

    Boyd, William Lowe; Wheaton, Dennis R.

    1983-01-01

    Professional literature about managing conflicts associated with declining enrollments indicates the existing tension in this area. A research study shows that, while upper-middle class districts may succeed using a rational approach to decision making, lower class districts, for various reasons, may not. Special problems of urban districts are…

  1. Regional District Attorney's Offices - Alaska Department of Law

    Science.gov (United States)

    District Stephen B. Wallace, District Attorney Physical Address: 204 Chief Eddie Hoffman Hwy. Bethel, AK Hours M-TH 8-4:30, F 8-12 Kenai - 3rd Judicial District Scot H. Leaders, District Attorney Trading Bay

  2. 78 FR 58049 - Proposed Establishment of the Adelaida District, Creston District, El Pomar District, Paso Robles...

    Science.gov (United States)

    2013-09-20

    ... Shallow, well- Deep alluvial Deep to moderate Mostly shallow drained, residual soils, with clay, depth... neither an approval nor an endorsement by TTB of the wine produced in that area. Requirements Section 4.25... Adelaida District viticultural area are hillside residual soils, which generally have shallow rooting...

  3. Clinical and pathological study on early diagnosis of Parkinson's disease and dementia with Lewy bodies

    International Nuclear Information System (INIS)

    Orimo, Satoshi

    2008-01-01

    [ 123 I] Meta-iodobenzylguanidine (MIBG) myocardial scintigraphy has been used to evaluate postganglionic cardiac sympathetic innervation in heart diseases and some neurological disorders. To see clinical usefulness of MIBG myocardial scintigraphy to differentiate Parkinson's disease (PD) and dementia with Lewy bodies (DLB) from related movement disorders and Alzheimer disease (AD), we performed MIBG myocardial scintigraphy in patients with these disorders. Cardiac uptake of MIBG is specifically reduced in PD and DLB, and this imaging approach is a sensitive diagnostic tool that possibly differentiates PD and DLB from related movement disorders and AD. To see pathological basis of the reduced cardiac uptake of MIBG in Lewy body disease, we immunohistichemically examined cardiac tissues from patients with PD, DLB, related movement disorders and AD using antibodies against tyrosine hydroxylase (TH) and phosphorylated neurofilament (NF). Not only TH- but also NF-immunoreactive (ir) axons in the epicardial nerve fascicles were markedly decreased in Lewy body disease, namely cardiac sympathetic denervation, which accounts for the reduced cardiac uptake of MIBG in Lewy body disease. Patients with PD and DLB have Lewy bodies (LBs) in the nervous system, whereas patients with multiple system atrophy (MSA), progressive supranuclear palsy, corticobasal degeneration, parkin-associated PD and AD have no LBs in the nervous system. Even in patients with MSA, cardiac sympathetic denervation was associated with the presence of LBs. Therefore, cardiac sympathetic denervation is closely related to the presence of LBs in a wide range of neurodegenerative processes. Taken together, we conclude that the reduced cardiac uptake of MIBG is a potential biomarker for the presence of LBs. Because α-synuclein is one of the key molecules in the pathogenesis of PD, we further investigate how α-synuclein aggregates are involved in degeneration of the cardiac sympathetic nerve in PD. We

  4. Interactions between Rocky Mountain Bighorn Sheep Ovis canadensis canadensis and Domestic Sheep Ovis aries and the Biological, Social, Economic, and Legal Implications of these Interactions on USDA Forest Service Lands in the Evanston/Mt. View Ranger District

    OpenAIRE

    Herrera, Ashly Nicole

    2012-01-01

    Strong evidence exists indicating domestic sheep (Ovis aries) can infect Rocky Mountain bighorn sheep (Ovis canadensis canadensis), a United States Forest Service (USFS) Region 4 sensitive species, with pneumonia (Callan 1991; Foreyt 1989, 1992, 1994; Foreyt and Lagerquist 1996; George et al 2008; Wehausen et al. 2011). Since the transmission of the pneumonic bacteria between the domestic and wild sheep is a result of bighorn sheep coming into contact with the bacteria carried in the mucous m...

  5. Fort Lewis natural gas and fuel oil energy baseline and efficiency resource assessment

    International Nuclear Information System (INIS)

    Brodrick, J.R.; Daellenbach, K.K.; Parker, G.B.; Richman, E.E.; Secrest, T.J.; Shankle, S.A.

    1993-02-01

    The mission of the US Department of Energy (DOE) Federal Energy Management Program (FEMP) is to lead the improvement of energy efficiency and fuel flexibility within the federal sector. Through the Pacific Northwest Laboratory (PNL), FEMP is developing a fuel-neutral approach for identifying, evaluating, and acquiring all cost-effective energy projects at federal installations; this procedure is entitled the Federal Energy Decision Screening (FEDS) system. Through a cooperative program between FEMP and the Army Forces Command (FORSCOM) for providing technical assistance to FORSCOM installations, PNL has been working with the Fort Lewis Army installation to develop the FEDS procedure. The natural gas and fuel oil assessment contained in this report was preceded with an assessment of electric energy usage that was used to implement a cofunded program between Fort Lewis and Tacoma Public Utilities to improve the efficiency of the Fort's electric-energy-using systems. This report extends the assessment procedure to the systems using natural gas and fuel oil to provide a baseline of consumption and an estimate of the energy-efficiency potential that exists for these two fuel types at Fort Lewis. The baseline is essential to segment the end uses that are targets for broad-based efficiency improvement programs. The estimated fossil-fuel efficiency resources are estimates of the available quantities of conservation for natural gas, fuel oils number-sign 2 and number-sign 6, and fuel-switching opportunities by level of cost-effectiveness. The intent of the baseline and efficiency resource estimates is to identify the major efficiency resource opportunities and not to identify all possible opportunities; however, areas of additional opportunity are noted to encourage further effort

  6. L-selectin-carbohydrate interactions: relevant modifications of the Lewis x trisaccharide.

    Science.gov (United States)

    Sanders, W J; Katsumoto, T R; Bertozzi, C R; Rosen, S D; Kiessling, L L

    1996-11-26

    Protein-carbohydrate interactions are known to mediate cell-cell recognition and adhesion events. Specifically, three carbohydrate binding proteins termed selectins (E-, P-, and L-selectin) have been shown to be essential for leukocyte rolling along the vascular endothelium, the first step in the recruitment of leukocytes from the blood into inflammatory sites or into secondary lymphoid organs. Although this phenomenon is well-established, little is known about the molecular-level interactions on which it depends. All three selectins recognize sulfated and sialylated derivatives of the Lewis x [Le(x):Gal beta 1-->4(Fuc alpha 1-->3)GlcNAc] and Lewis a [Le(a): Gal beta 1-->3(Fuc alpha 1-->4)GlcNAc] trisaccharide cores with affinities in the millimolar range, and it is believed that variants of these structures are the carbohydrate determinants of selectin recognition. Recently it was shown that the mucin GlyCAM-1, a secreted physiological ligand for L-selectin, is capped with sulfated derivatives of sialyl Lewis x [sLe(x): Sia alpha 2-->3Gal beta 1-->4(Fuc alpha 1-->3)GlcNAc] and that sulfation is required for the high-affinity interaction between GlyCAM-1 and L-selectin. To elucidate the important sites of sulfation on Le(x) with respect to L-selectin recognition, we have synthesized six sulfated Le(x) analogs and determined their abilities to block binding of a recombinant L-selectin-Ig chimera to immobilized GlyCAM-1. Our results suggest that 6-sulfo sLe(x) binds to L-selectin with higher affinity than does sLe(x) or 6'-sulfo sLe(x) and that sulfation of sLe(x) capping groups on GlyCAM-1 at the 6-position is important for L-selectin recognition.

  7. Lewis Acid-Base Chemistry of 7-Azaisoindigo-Based Organic Semiconductors.

    Science.gov (United States)

    Randell, Nicholas M; Fransishyn, Kyle M; Kelly, Timothy L

    2017-07-26

    Low-band-gap organic semiconductors are important in a variety of organic electronics applications, such as organic photovoltaic devices, photodetectors, and field effect transistors. Building on our previous work, which introduced 7-azaisoindigo as an electron-deficient building block for the synthesis of donor-acceptor organic semiconductors, we demonstrate how Lewis acids can be used to further tune the energies of the frontier molecular orbitals. Coordination of a Lewis acid to the pyridinic nitrogen of 7-azaisoindigo greatly diminishes the electron density in the azaisoindigo π-system, resulting in a substantial reduction in the lowest unoccupied molecular orbital (LUMO) energy. This results in a smaller highest occupied molecular orbital-LUMO gap and shifts the lowest-energy electronic transition well into the near-infrared region. Both H + and BF 3 are shown to coordinate to azaisoindigo and affect the energy of the S 0 → S 1 transition. A combination of time-dependent density functional theory and UV/vis and 1 H NMR spectroscopic titrations reveal that when two azaisoindigo groups are present and high concentrations of acid are used, both pyridinic nitrogens bind Lewis acids. Importantly, we demonstrate that this acid-base chemistry can be carried out at the solid-vapor interface by exposing thin films of aza-substituted organic semiconductors to vapor-phase BF 3 ·Et 2 O. This suggests the possibility of using the BF 3 -bound 7-azaisoindigo-based semiconductors as n-type materials in various organic electronic applications.

  8. The μ3 model of acids and bases: extending the Lewis theory to intermetallics.

    Science.gov (United States)

    Stacey, Timothy E; Fredrickson, Daniel C

    2012-04-02

    A central challenge in the design of new metallic materials is the elucidation of the chemical factors underlying the structures of intermetallic compounds. Analogies to molecular bonding phenomena, such as the Zintl concept, have proven very productive in approaching this goal. In this Article, we extend a foundational concept of molecular chemistry to intermetallics: the Lewis theory of acids and bases. The connection is developed through the method of moments, as applied to DFT-calibrated Hückel calculations. We begin by illustrating that the third and fourth moments (μ(3) and μ(4)) of the electronic density of states (DOS) distribution tune the properties of a pseudogap. μ(3) controls the balance of states above and below the DOS minimum, with μ(4) then determining the minimum's depth. In this way, μ(3) predicts an ideal occupancy for the DOS distribution. The μ(3)-ideal electron count is used to forge a link between the reactivity of transition metals toward intermetallic phase formation, and that of Lewis acids and bases toward adduct formation. This is accomplished through a moments-based definition of acidity which classifies systems that are electron-poor relative to the μ(3)-ideal as μ(3)-acidic, and those that are electron-rich as μ(3)-basic. The reaction of μ(3) acids and bases, whether in the formation of a Lewis acid/base adduct or an intermetallic phase, tends to neutralize the μ(3) acidity or basicity of the reactants. This μ(3)-neutralization is traced to the influence of electronegativity differences at heteroatomic contacts on the projected DOS curves of the atoms involved. The role of μ(3)-acid/base interactions in intermetallic phases is demonstrated through the examination of 23 binary phases forming between 3d metals, the stability range of the CsCl type, and structural trends within the Ti-Ni system.

  9. Land application of mine water causes minimal uranium loss offsite in the wet-dry tropics: Ranger Uranium Mine, Northern Territory, Australia.

    Science.gov (United States)

    Mumtaz, Saqib; Streten, Claire; Parry, David L; McGuinness, Keith A; Lu, Ping; Gibb, Karen S

    2015-11-01

    Ranger Uranium Mine (RUM) is situated in the wet-dry tropics of Northern Australia. Land application (irrigation) of stockpile (ore and waste) runoff water to natural woodland on the mine lease is a key part of water management at the mine. Consequently, the soil in these Land Application Areas (LAAs) presents a range of uranium (U) and other metals concentrations. Knowledge of seasonal and temporal changes in soil U and physicochemical parameters at RUM LAAs is important to develop suitable management and rehabilitation strategies. Therefore, soil samples were collected from low, medium, high and very high U sites at RUM LAAs for two consecutive years and the effect of time and season on soil physicochemical parameters particularly U and other major solutes applied in irrigation water was measured. Concentrations of some of the solutes applied in the irrigation water such as sulphur (S), iron (Fe) and calcium (Ca) showed significant seasonal and temporal changes. Soil S, Fe and Ca concentration decreased from year 1 to year 2 and from dry to wet seasons during both years. Soil U followed the same pattern except that we recorded an increase in soil U concentrations at most of the RUM LAAs after year 2 wet season compared to year 2 dry season. Thus, these sites did not show a considerable decrease in soil U concentration from year 1 to year 2. Sites which contained elevated U after wet season 2 also had higher moisture content which suggests that pooling of U containing rainwater at these sites may be responsible for elevated U. Thus, U may be redistributed within RUM LAAs due to surface water movement. The study also suggested that a decrease in U concentrations in LAA soils at very high U (>900 mg kg(-1)) sites is most likely due to transport of particulate matter bound U by surface runoff and U may not be lost from the surface soil due to vertical movement through the soil profile. Uranium attached to particulate matter may reduce its potential for environmental

  10. Did Immanuel Kant have dementia with Lewy bodies and REM behavior disorder?

    Science.gov (United States)

    Miranda, Marcelo; Slachevsky, Andrea; Garcia-Borreguero, Diego

    2010-06-01

    Immanuel Kant, one of the most brilliant minds of the XVIII century and of western philosophy, suffered from dementia in his late years. Based on the analysis of testimonies of his close friends, in this report we describe his neurological disorder which, after 8years of evolution, led to his death. His cognitive decline was strongly associated with a parasomnia compatible with a severe rapid eye movement (REM) behavior disorder (RBD) and dementia with Lewy bodies. Copyright 2010 Elsevier B.V. All rights reserved.

  11. Demystifying the constancy of the Ermakov-Lewis invariant for a time-dependent oscillator

    Science.gov (United States)

    Padmanabhan, T.

    2018-03-01

    It is well known that the time-dependent harmonic oscillator (TDHO) possesses a conserved quantity, usually called Ermakov-Lewis invariant. I provide a simple physical interpretation of this invariant as well as a whole family of related invariants. This interpretation does not seem to have been noticed in the literature before. The procedure also allows one to tackle some key conceptual issues which arise in the study of quantum fields in the external, time-dependent backgrounds like in the case of particle production in an expanding universe and Schwinger effect.

  12. Interphase transfer kinetics of uranium using the drop method, Lewis cell, and Kenics mixer

    International Nuclear Information System (INIS)

    Horner, D.E.; Mailen, J.C.; Thiel, S.W.; Scott, T.C.; Yates, R.G.

    1979-05-01

    The rate constants for the interphase transfer of uranium between 3.5 M HNO 3 and tributyl phosphate (TBP) - normal hydrocarbon diluent solutions have been measured using the single drop method, Lewis cell method, and a Kenics mixer - centrifugal separator. Rate constants obtained by all methods were the same within experimental error. The variables studied that affect the rate constants include the TBP concentration, the acidity and total neutral nitrate concentrations of the aqueous phase, and temperature. Results of these tests indicate that the rate controlling mechanism is chemical reaction at the interface

  13. Gothic elements in contemporary detective story : Matthew Gregory Lewis and Minette Walters compared

    Directory of Open Access Journals (Sweden)

    Vesna Marinko

    2009-12-01

    Full Text Available One of the most shocking Gothic novels was written by Matthew Gregory Lewis in 1796. His Gothic novel The Monk contains all the typical Gothic elements such as a ruined castle, aggressive villain, women in distress, the atmosphere of terror and horror and a lot more. This article analyses and compares to what extent the Gothic elements of the late 18th century survived in the contemporary detective story The Ice House (1993 written by Minette Walters and how these elements have changed.

  14. The study of fMRI in Alzheimer's disease, frontotemporal dementia and Lewy bodies dementia

    International Nuclear Information System (INIS)

    Zhang Bing; Xu Jun; Xu Yun; Zhu Bin

    2010-01-01

    Alzheimer's disease (AD), dementia with Lewy bodies (DLB) and frontotemporal dementia (FTD) are the main type of neuro degenerative diseases, but the FTD and DLB are always confused with AD. Structural MRI, diffusion-weighted imaging and proton magnetic resonance spectroscopy have the potential to support the diagnosis of AD and the relative disease. Brain atrophy pattern, apparent diffusion coefficient and fractional anisotropy pattern, the distribution mode of N-acetylaspartate and myo-inositol in temporal lobe, hippocampus, parietal lobe, frontal lobe could help to differentiate AD from FTD, DLB and those patterns are in accordance with the pathological changes. (authors)

  15. Verba tene, res sequentur. Lewis Carroll’s play on words and linguistic-textual generation

    OpenAIRE

    Katajamäki, Sakari

    2016-01-01

    In the beginning of Lewis Carroll’s Through the Looking-Glass (1872), the chessman White King is writing a note in his memorandum book, but his pencil does not obey him. The poor King struggles with it but, despite his efforts, he is not able to write what he intends. The text that appears in his book is something entirely peculiar and contrary to his intention: “The White Knight is sliding down the poker. He balances badly.” This episode reflects the manner in which language is often represe...

  16. Recent advances in Ni-H2 technology at NASA Lewis Research Center

    Science.gov (United States)

    Gonzalezsanabria, O. D.; Britton, D. L.; Smithrick, J. J.; Reid, M. A.

    1986-01-01

    The NASA Lewis Research Center has concentrated its efforts on advancing the Ni-H2 system technology for low Earth orbit applications. Component technology as well as the design principles were studied in an effort to understand the system behavior and failure mechanisms in order to increase performance and extend cycle life. The design principles were previously addressed. The component development is discussed, in particular the separator and nickel electrode and how these efforts will advance the Ni-H2 system technology.

  17. General aviation internal combustion engine research programs at NASA-Lewis Research Center

    Science.gov (United States)

    Willis, E. A.

    1978-01-01

    An update is presented of non-turbine general aviation engine programs underway at the NASA-Lewis Research Center in Cleveland, Ohio. The program encompasses conventional, lightweight diesel and rotary engines. Its three major thrusts are: (a) reduced SFC's; (b) improved fuels tolerance; and (c) reducing emissions. Current and planned future programs in such areas as lean operation, improved fuel management, advanced cooling techniques and advanced engine concepts, are described. These are expected to lay the technology base, by the mid to late 1980's, for engines whose life cycle fuel costs are 30 to 50% lower than today's conventional engines.

  18. Lewis, S

    Energy Technology Data Exchange (ETDEWEB)

    1978-03-01

    This paper briefly reviews the investigation between 1969 and 1975 into substitutes for chock support timber. The parameters for the design of the substitutes were very exacting, having been based on the original material and as the investigation progressed it was necessary to modify and make changes. Of the large variety of materials tested the discard was considerable; however suitable ductile structures were found, utilizing reinforced autoclaved aerated concrete. Successful laboratory testing was eventually confirmed by satisfactory trials in a number of underground situations.

  19. Nuclear power for district heating

    International Nuclear Information System (INIS)

    Lyon, R.B.; Sochaski, R.O.

    1975-09-01

    Current district heating trends are towards an increasing use of electricity. This report concerns the evaluation of an alternative means of energy supply - the direct use of thermal energy from CANDU nuclear stations. The energy would be transmitted via a hot fluid in a pipeline over distances of up to 40 km. Advantages of this approach include a high utilization of primary energy, with a consequent reduction in installed capacity, and load flattening due to inherent energy storage capacity and transport delays. Disadvantages include the low load factors for district heating, the high cost of the distribution systems and the necessity for large-scale operation for economic viability. This requirement for large-scale operation from the beginning could cause difficulty in the implementation of the first system. Various approaches have been analysed and costed for a specific application - the supply of energy to a district heating load centre in Toronto from the location of the Pickering reactor station about 40 km away. (author)

  20. 76 FR 52930 - Availability of Decisions

    Science.gov (United States)

    2011-08-24

    ... Forest Supervisor Decisions Laramie Daily Boomerang, published daily in Laramie, Albany County, Wyoming. District Ranger Decisions Laramie District: Laramie Daily Boomerang, published daily in Laramie, Albany...

  1. Guidelines for District Heating Substations

    Energy Technology Data Exchange (ETDEWEB)

    2009-07-15

    The present guidelines contain a set of recommendations focusing on planning, installation, use and maintenance of district heating (DH) substations within district heating systems throughout Europe. The recommendations were developed in order to enable readers to develop well-functioning substations and an effective heat and domestic warm water delivery. These guidelines are intended to give the most effective overall solutions for various parts of the customer installation. The guidelines are not meant to specify the different components of the substation such as meters or heat exchangers. The guidelines deal with a wide variety of issues concerning both present systems of today and district heating systems of the future. Specific handling and maintenance recommendations are mainly focused on present modern systems but are also intended to cover the future situation as much as is feasible. For this reason, certain existing systems are not dealt with in these guidelines. For instance, these guidelines do not cover steam systems, systems with temperatures exceeding 110 deg C and pressure levels above 1.6 MPa. The guidelines include a chapter on the heat meter, as the meter and especially the meter installation is always installed simultaneously with the rest of the substation. These guidelines aim to provide best-practice and easy-to-handle recommendations for: - those who are responsible for relations between district heating utilities and customers; - those who own or maintain a building connected to the district heating network; - those who manufacture, plan, purchase, test and install substations. These guidelines do not deal with investment or cost aspects, but in general, Euroheat and Power recommends looking at the lifetime cost of all components of the substation, instead of investment costs alone. An example of this is provided in Chapter 7.8. The Guidelines were developed based on the most optimal operating principles of substations and meters

  2. Quetiapine effective in treatment of inappropriate sexual behavior of lewy body disease with predominant frontal lobe signs.

    Science.gov (United States)

    Prakash, Ravi; Pathak, Amit; Munda, Sanjay; Bagati, Dhruv

    2009-01-01

    Dementia of Lewy body disease is the second most common degenerative cause of dementia after Alzheimer's disease, among all the dementias. The core features are a progressive dementia, fluctuations in cognitive functions, visual hallucinations, and spontaneous parkinsonism. Rapid eye movement sleep behavior disorder, severe neuroleptic sensitivity, and low dopamine transporter uptake in basal ganglia are other suggestive features. Behavioral abnormalities are commonly present in the form of aggressive behavior, irritability, and uninhibited behaviors. These are mostly seen in the advanced stages of dementia. However, inappropriate sexual behavior is uncommonly seen in such cases. Three types of inappropriate sexual behaviors commonly found in cases of dementia are sex talks, sexual acts, and implied sexual acts. Such inappropriate sexual behaviors have not been described adequately in dementia of Lewy body disease. We report inappropriate sexual behaviors in a case of dementia of Lewy body disease, which improved rapidly after treatment with quetiapine.

  3. Calibration and comparison of the NASA Lewis free-piston Stirling engine model predictions with RE-1000 test data

    Science.gov (United States)

    Geng, Steven M.

    1987-01-01

    A free-piston Stirling engine performance code is being upgraded and validated at the NASA Lewis Research Center under an interagency agreement between the Department of Energy's Oak Ridge National Laboratory and NASA Lewis. Many modifications were made to the free-piston code in an attempt to decrease the calibration effort. A procedure was developed that made the code calibration process more systematic. Engine-specific calibration parameters are often used to bring predictions and experimental data into better agreement. The code was calibrated to a matrix of six experimental data points. Predictions of the calibrated free-piston code are compared with RE-1000 free-piston Stirling engine sensitivity test data taken at NASA Lewis. Resonable agreement was obtained between the code predictions and the experimental data over a wide range of engine operating conditions.

  4. Self-Assembled Nanocomposite Organic Polymers with Aluminum and Scandium as Heterogeneous Water-Compatible Lewis Acid Catalysts.

    Science.gov (United States)

    Miyamura, Hiroyuki; Sonoyama, Arisa; Hayrapetyan, Davit; Kobayashi, Shū

    2015-09-01

    While water-compatible Lewis acids have great potential as accessible and environmentally benign catalysts for various organic transformations, efficient immobilization of such Lewis acids while keeping high activity and without leaching of metals even under aqueous conditions is a challenging task. Self-assembled nanocomposite catalysts of organic polymers, carbon black, aluminum reductants, and scandium salts as heterogeneous water-compatible Lewis acid catalysts are described. These catalysts could be successfully applied to various C-C bond-forming reactions without leaching of metals. Scanning transmission electron microscopy analyses revealed that the nanocomposite structure of Al and Sc was fabricated in these heterogeneous catalysts. It is noted that Al species, which are usually decomposed rapidly in the presence of water, are stabilized under aqueous conditions. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Controlled synthesis of multi-morphology Te crystals by a convenient Lewis acid/base-assisted solvothermal method

    International Nuclear Information System (INIS)

    Wu Xiaoping; Yuan Lin; Zhou Shaomin; Lou Shiyun; Wang Yongqiang; Gao Tao; Liu YuBiao; Shi Xiaojing

    2012-01-01

    This paper reports on the controlled growth of multi-morphology Te crystals by a convenient Lewis acid/base-assisted solvothermal method for the first time. The morphological transformation from one-dimension (1D) nanostructures to 2D hierarchical flowerlike microarchitecture has been observed. The nanorods and nanowires with a well-defined crystallographical structure and the hierarchical flowers microarchitecture were obtained by changing the Lewis acids/bases. Lewis acids/bases were found to be crucial for the formation of the products by not only acting as the pH regulator but also as the shape controller, owing to their hydrolysis in the solvent to in situ form H + /OH − and hydrates. The results suggest that this should be an effective approach to the control the growth of t-Te crystals with interesting multiple morphologies, which are of interest for both theoretical investigations and practical applications.

  6. Familial diffuse Lewy body disease, eye movement abnormalities, and distribution of pathology.

    Science.gov (United States)

    Brett, Francesca M; Henson, Craig; Staunton, Hugh

    2002-03-01

    Familial diffuse Lewy body disease (DLBD) is rare and not yet associated with a defect in the synuclein gene. In the differential diagnosis of the parkinsonian syndromes, defects in vertical gaze tend to be identified with progressive supranuclear palsy. False-positive diagnosis of progressive supranuclear palsy can occur, and defects in vertical gaze have been reported in DLBD, although so far a pure vertical gaze palsy associated with pathological abnormalities in the substrate for vertical gaze has not been described. To report the clinical and pathological findings in 2 siblings with DLBD, and to relate the distribution of the pathological abnormalities in the brainstem to centers for vertical gaze. For several years, 2 Irish siblings experienced a progressive parkinsonism-dementia complex associated in one with a defect in vertical gaze and in both with visual hallucinations. In both patients, results of pathological examination revealed (1) Lewy bodies positive for ubiquitin and alpha-synuclein together with cell loss and gliosis in the substantia nigra, locus ceruleus, and neocortex; and (2) similar findings in the rostral interstitial nucleus of the medial longitudinal fasciculus, the posterior commissure, and the interstitial nucleus of Cajal (substrates for vertical gaze). Familial DLBD (not shown to be genetically as distinct from environmentally transmitted) has been shown to exist in an Irish family. Caution should be enjoined in the interpretation of defects in vertical gaze in the differential diagnosis of the parkinsonian syndromes.

  7. Serum expression of HA and LN in lewis rat models of autoimmune myocarditis

    International Nuclear Information System (INIS)

    Han Li'na; Li Tieling; Zhang Yajing; Yang Tingshu; Ding Yu; Guo Shuli; Zhao Xiaoning

    2011-01-01

    Objective: To study the clinical significance of dynamic changes of serum expressions of hyaluronic acid (HA) and laminin (LN) in Lewis rat models of experimental autoimmune myocarditis (EAM). Methods: Fifty Lewis rat models of experimental autoimmune myocarditis (EAM) were established with injection of recombinant cardiac C protein with complete freund adjuvant into two foot-pads plus intraperitoneal injection of pertussis toxin. At 1w, 2w, 4w, 6w and 8w, 10 models were sacrificed each time;cardiac tissues were examined with HE stain for myocardial inflammatory score and examined with picrosirius red stain for myocardial fibrosis score, also, serum HA and LN expressions were determined with RIA. These examinations were performed in 10 undisturbed animals as controls. Results: The myocardial inflammatory scores of the models at 1w were about the same as those in the controls, but the scores rapidly increased from 2w on to 4w then fell gradually. The myocardial fibrosis scores of the models at 1wk were also not much different from those in controls. The fibrosis scores increased rapidly at 4w and maintained at high level up to 8w. The changes of serum expressions of HA and LN roughly paralleled those of myocardial fibrosis scores i. e. rapidly increased at 4w up to 8w. Conclusion: Serum expressions of HA and LN could faithfully reflect the degree of myocardial fibrosis in rat models of EAM. HA and LN were useful markers of myocardial fibrois and were of prognostic importance. (authors)

  8. Lewis basicity, adhesion thermodynamic work and coordinating ability on aminated silicon surfaces

    International Nuclear Information System (INIS)

    Sánchez, M. Alejandra; Paniagua, Sergio A.; Borge, Ignacio; Viales, Christian; Montero, Mavis L.

    2014-01-01

    Highlights: • Silicon(1 0 0) surfaces with diamines followed by anchoring of copper complexes over the diamine layer, an approach that could be used for advanced functionalization of semiconducting surfaces. • Lewis basicity (using Fowkes–van Oss–Chaudhury–Good surface tension model) and adhesion thermodynamic work (using chemical force microscopy) were determined. • Higher basicity and thermodynamic work correlate with selective copper acetate monolayer grow. The cyclic voltammetry studies confirm the confined copper redox activity. - Abstract: Silicon(1 0 0) surfaces have been modified with three different amines (aniline, benzylamine and dodecylamine) and diamines (4-aminopyridine, 4-aminomethylpyridine, 1,12-dodecyldiamine). The surface energy was measured by contact angle technique. For Si-diamine surfaces, Lewis basicity (using Fowkes–van Oss–Chaudhury–Good surface tension model) and adhesion thermodynamic work (using chemical force microscopy) were determined. We related these data, the amine/diamine nature and their geometry on the surface (via DFT calculations) with the consequent ability to coordinate copper(II) acetate. Finally, copper(II) acetate monolayers behavior was studied by cyclic voltammetry

  9. Cholinergic and dopaminergic activities in senile dementia of Lewy body type.

    Science.gov (United States)

    Perry, E K; Marshall, E; Perry, R H; Irving, D; Smith, C J; Blessed, G; Fairbairn, A F

    1990-01-01

    Analyses of brain tissue in a recently identified group of elderly demented patients suggest a neurochemical basis for some of the clinical features. Senile dementia of the Lewy body type (SDLT) can be distinguished from classical Alzheimer disease (AD) clinically by its acute presentation with confusion frequently accompanied by visual hallucinations, and neuropathologically by the presence of Lewy bodies and senile plaques (but not generally neurofibrillary tangles) in the cerebral cortex. Reductions in the cortical cholinergic enzyme choline acetyltransferase were more pronounced in individuals with (80%) compared to those without (50%) hallucinations and correlated strongly with mental test scores in the group as a whole. In the caudate nucleus, dopamine levels were related to the number of neurons in the substantia nigra, there being a 40-60% loss of both in SDLT--probably accounting for mild extrapyramidal features in some of these cases--compared with an 80% loss in Parkinson disease and no change in AD. The cholinergic correlates of mental impairment in SDLT together with the relative absence of cortical neurofibrillary tangles and evidence for postsynaptic cholinergic receptor compensation raise the question of whether this type of dementia may be more amenable to cholinotherapy than classical AD.

  10. Diffusible gradients are out - an interview with Lewis Wolpert. Interviewed by Richardson, Michael K.

    Science.gov (United States)

    Wolpert, Lewis

    2009-01-01

    In 1969, Lewis Wolpert published a paper outlining his new concepts of "pattern formation" and "positional information". He had already published research on the mechanics of cell membranes in amoebae, and a series of classic studies of sea urchin gastrulation with Trygve Gustavson. Wolpert had presented his 1969 paper a year earlier at a Woods Hole conference, where it received a very hostile reception: "I wasnt asked back to America for many years!". But with Francis Crick lining up in support of diffusible morphogen gradients, positional information eventually became established as a guiding principle for research into biological pattern formation. It is now clear that pattern formation is much more complex than could possibly have been imagined in 1969. But Wolpert still believes in positional information, and regards intercalation during regeneration as its best supporting evidence. However, he and others doubt that diffusible morphogen gradients are a plausible mechanism: "Diffusible gradients are too messy", he says. Since his retirement, Lewis Wolpert has remained active as a theoretical biologist and continues to publish in leading journals. He has also campaigned for a greater public understanding of the stigma of depression. He was interviewed at home in London on July 26th, 2007 by Michael Richardson.

  11. Reflections on Centaur Upper Stage Integration by the NASA Lewis (Glenn) Research Center

    Science.gov (United States)

    Graham, Scott R.

    2015-01-01

    The NASA Glenn (then Lewis) Research Center (GRC) led several expendable launch vehicle (ELV) projects from 1963 to 1998, most notably the Centaur upper stage. These major, comprehensive projects included system management, system development, integration (both payload and stage), and launch operations. The integration role that GRC pioneered was truly unique and highly successful. Its philosophy, scope, and content were not just invaluable to the missions and vehicles it supported, but also had significant Agency-wide benefits. An overview of the NASA Lewis Research Center (now the NASA Glenn Research Center) philosophy on ELV integration is provided, focusing on Atlas/Centaur, Titan/Centaur, and Shuttle/Centaur vehicles and programs. The necessity of having a stable, highly technically competent in-house staff is discussed. Significant depth of technical penetration of contractor work is another critical component. Functioning as a cohesive team was more than a concept: GRC senior management, NASA Headquarters, contractors, payload users, and all staff worked together. The scope, content, and history of launch vehicle integration at GRC are broadly discussed. Payload integration is compared to stage development integration in terms of engineering and organization. Finally, the transition from buying launch vehicles to buying launch services is discussed, and thoughts on future possibilities of employing the successful GRC experience in integrating ELV systems like Centaur are explored.

  12. Alpha-synuclein oligomers - neurotoxic molecules in Parkinson’s disease and other Lewy body disorders

    Directory of Open Access Journals (Sweden)

    Martin Ingelsson

    2016-09-01

    Full Text Available Adverse intra- and extracellular effects of toxic α-synuclein are believed to be central to the pathogenesis in Parkinson’s disease and other disorders with Lewy body pathology in the nervous system. One of the physiological roles of α-synuclein relates to the regulation of neurotransmitter release at the presynapse, although it is still unclear whether this mechanism depends on the action of monomers or smaller oligomers. As for the pathogenicity, accumulating evidence suggest that prefibrillar species, rather than the deposits per se, are responsible for the toxicity in affected cells. In particular, larger oligomers or protofibrils of α-synuclein have been shown to impair protein degradation as well as the function of several organelles, such as the mitochondria and the endoplasmic reticulum. Accumulating evidence further suggest that oligomers/protofibrils may have a toxic effect on the synapse, which may lead to disrupted electrophysiological properties. In addition, recent data indicate that oligomeric α-synuclein species can spread between cells, either as free-floating proteins or via extracellular vesicles, and thereby act as seeds to propagate disease between interconnected brain regions. Taken together, several lines of evidence suggest that α-synuclein have neurotoxic properties and therefore should be an appropriate molecular target for therapeutic intervention in Parkinson’s disease and other disorders with Lewy pathology. In this context, immunotherapy with monoclonal antibodies against α-synuclein oligomers/protofibrils should be a particularly attractive treatment option.

  13. Recombinant human endostatin improves tumor vasculature and alleviates hypoxia in Lewis lung carcinoma

    International Nuclear Information System (INIS)

    Peng Fang; Wang Jin; Zou Yi; Bao Yong; Huang Wenlin; Chen Guangming; Luo Xianrong; Chen Ming

    2011-01-01

    Objective: To investigate whether recombinant human endostatin can create a time window of vascular normalization prior to vascular pruning to alleviate hypoxia in Lewis lung carcinoma in mice. Methods: Kinetic changes in morphology of tumor vasculature in response to recombinant human endostatin were detected under a confocal microscope with immunofluorescent staining in Lewis lung carcinomas in mice. The hypoxic cell fraction of different time was assessed with immunohistochemical staining . Effects on tumor growth were monitored as indicated in the growth curve of tumors . Results: Compared with the control group vascularity of the tumors was reduced over time by recombinant human endostatin treatment and significantly regressed for 9 days. During the treatment, pericyte coverage increased at day 3, increased markedly at day 5, and fell again at day 7. The vascular basement membrane was thin and closely associated with endothelial cells after recombinant human endostatin treatment, but appeared thickened, loosely associated with endothelial cells in control tumors. The decrease in hypoxic cell fraction at day 5 after treatment was also found. Tumor growth was not accelerated 5 days after recombinant human endostatin treatment. Conclusions: Recombinant human endostatin can normalize tumor vasculature within day 3 to 7, leading to improved tumor oxygenation. The results provide important experimental basis for combining recombinant human endostatin with radiation therapy in human tumors. (authors)

  14. Narrative Organization Deficit in Lewy Body Disorders Is Related to Alzheimer Pathology.

    Science.gov (United States)

    Grossman, Murray; Irwin, David J; Jester, Charles; Halpin, Amy; Ash, Sharon; Rascovsky, Katya; Weintraub, Daniel; McMillan, Corey T

    2017-01-01

    Background: Day-to-day interactions depend on conversational narrative, and we examine here the neurobiological basis for difficulty organizing narrative discourse in patients with Lewy body disorders (LBD). Method: Narrative organization was examined in 56 non-aphasic LBD patients, including a non-demented cohort ( n = 30) with Parkinson's disease (PD) or PD-Mild Cognitive Impairment PD-MCI,) and a cohort with mild dementia ( n = 26) including PD-dementia (PDD) and dementia with Lewy bodies (DLB), with similar age and education but differing in MMSE ( p organization of brief, familiar narratives (e.g., going fishing, wrapping a present). A subgroup of 24 patients had MRI assessment of regional gray matter (GM) atrophy and cerebrospinal fluid (CSF) levels of biomarkers for Alzheimer's disease (AD) pathology, including beta amyloid (Aβ), total-tau ( t -tau), and phosphorylated-tau ( p -tau). Results: Mildly demented LBD patients had a significant deficit judging narratives compared to non-demented patients, but this deficit was not correlated with MMSE. Regression analyses instead related narrative organization to regions of frontal GM atrophy, and CSF levels of Aβ and t -tau associated with presumed AD pathology in these frontal regions. Conclusion: These findings are consistent with the hypothesis that CSF markers of AD pathology associated with frontal regions play a role in difficulty organizing narratives in LBD.

  15. Numerical Modeling of Climatic Change from the Terminus Record of Lewis Glacier, Mount Kenya.

    Science.gov (United States)

    Kruss, Phillip Donald

    Over the last 100 years, the glaciers and lakes of East Africa have undergone dramatic change in response to climatic forcing. However, the available conventional meterological series have not proven sufficient to explain these environmental events. The secular climatic change at Lewis Glacier, Mount Kenya (0(DEGREES)9'S, 37(DEGREES)19'E), is reconstructed from its terminus record documented since 1893. The short-time-step numerical model developed for this study consists of climate and ice dynamics segments. The climate segment directly computes the effect on the net balance of change in the four forcings: precipitation, albedo, cloudiness, and temperature. The flow segment calculates the dynamic glacier response to net balance variation. Climatic change occurs over a wide range of time scales. Each glacier responds in a unique fashion to this spectrum of climatic forcings. The response of the Lewis terminus extent to repeated sinusoidal fluctuation in the net balance is calculated. The net balance versus elevation profile is separately translated along the orthogonal balance and elevation axes. Net balance amplitudes of 0.1 to 0.5 m a('-1) of ice and 10 to 50 m elevation, respectively, and periods ranging from 20 to 1000 years are covered. Consideration of the Lewis response is perspective with similar results for Hintereisferner, Storglaciaren, and Berendon and South Cascade Glaciers identifies general characteristics of the time lag and amplitude of the terminus response. The magnitude and timing of the change in only one of the climatic forcings precipitation, albedo, cloudiness, or temperature necessary to produce the retreat of the Lewis terminus from its late 19th century maximum are computed. Equivalent changes for two scenarios of simultaneous variation, namely precipitation/albedo/cloudiness and temperature/albedo, are also estimated. These numerical results are interpreted in the light of long-term lake level, river flow, and instrumental information. A

  16. An exploratory study of proficient undergraduate Chemistry II students' application of Lewis's model

    Science.gov (United States)

    Lewis, Sumudu R.

    This exploratory study was based on the assumption that proficiency in chemistry must not be determined exclusively on students' declarative and procedural knowledge, but it should be also described as the ability to use variety of reasoning strategies that enrich and diversify procedural methods. The study furthermore assumed that the ability to describe the structure of a molecule using Lewis's model and use it to predict its geometry as well as some of its properties is indicative of proficiency in the essential concepts of covalent bonding and molecule structure. The study therefore inquired into the reasoning methods and procedural techniques of proficient undergraduate Chemistry II students when solving problems, which require them to use Lewis's model. The research design included an original survey, designed by the researcher for this study, and two types of interviews, with students and course instructors. The purpose of the survey was two-fold. First and foremost, the survey provided a base for the student interview selection, and second it served as the foundation for the inquiry into the strategies the student use when solving survey problems. Twenty two students were interviewed over the course of the study. The interview with six instructors allowed to identify expected prior knowledge and skills, which the students should have acquired upon completion of the Chemistry I course. The data, including videos, audios, and photographs of the artifacts produced by students during the interviews, were organized and analyzed manually and using QSR NVivo 10. The research found and described the differences between proficient and non-proficient students' reasoning and procedural strategies when using Lewis's model to describe the structure of a molecule. One of the findings clearly showed that the proficient students used a variety of cues to reason, whereas other students used one memorized cue, or an algorithm, which often led to incorrect representations in

  17. Lewis base catalyzed 1,3-dithiane addition to carbonyl and imino compounds using 2-trimethylsilyl-1,3-dithiane.

    Science.gov (United States)

    Michida, Makoto; Mukaiyama, Teruaki

    2008-09-01

    Lewis base-catalyzed 1,3-dithiane addition to electrophiles such as carbonyl compounds and N-substituted aldimines with 2-trimethylsilyl-1,3-dithiane (TMS-dithiane) is described. By the activation of the carbon-silicon bond in the presence of a Lewis base catalyst such as tetrabutylammonium phenoxide (PhONnBu(4)), a 1,3-dithiane addition reaction proceeded smoothly to afford the corresponding adducts in good to high yields under mild conditions. This synthesis is also applied to the reactions of ketones having alpha-protons, and of N-substituted aldimines.

  18. Tailoring the Synergistic Bronsted-Lewis acidic effects in Heteropolyacid catalysts: Applied in Esterification and Transesterification Reactions

    OpenAIRE

    Tao, Meilin; Xue, Lifang; Sun, Zhong; Wang, Shengtian; Wang, Xiaohong; Shi, Junyou

    2015-01-01

    In order to investigate the influences of Lewis metals on acidic properties and catalytic activities, a series of Keggin heteropolyacid (HPA) catalysts, HnPW11MO39 (M = TiIV, CuII, AlIII, SnIV, FeIII, CrIII, ZrIV and ZnII; for Ti and Zr, the number of oxygen is 40), were prepared and applied in the esterification and transesterification reactions. Only those cations with moderate Lewis acidity had a higher impact. Ti Substituted HPA, H5PW11TiO40, posse lower acid content compared with TixH3−4...

  19. FROM THE LEWIS AND CLARK EXPEDITION TO IBM, DELL, AND SOUTHWEST AIRLINES: TEACHING HISTORY AND LEADERSHIP TO BUSINESS STUDENTS

    Directory of Open Access Journals (Sweden)

    Jeffrey J. Matthews

    2006-01-01

    Full Text Available History is not a tomb of dead facts but a resource that can inform and improve everyday decision making. Experience as an analytical tool is invaluable for solving problems in changing and competitive environments. “From the Lewis and Clark Expedition,” which coincides with the National Lewis & Clark Bicentennial Commemoration (2003—2006, demonstrates how contemporary business concepts of visionary leadership, systematic planning, and organizational climate were instrumental to the success of Thomas Jefferson's “Corps of Discovery” and shows how a mastery of these concepts contributed to the successes of the pioneering US corporations IBM, Southwest Airlines, and Dell.

  20. Investigation of prototypal MOFs consisting of polyhedral cages with accessible Lewis-acid sites for quinoline synthesis.

    Science.gov (United States)

    Gao, Wen-Yang; Leng, Kunyue; Cash, Lindsay; Chrzanowski, Matthew; Stackhouse, Chavis A; Sun, Yinyong; Ma, Shengqian

    2015-03-21

    A series of prototypal metal-organic frameworks (MOFs) consisting of polyhedral cages with accessible Lewis-acid sites, have been systematically investigated for Friedländer annulation reaction, a straightforward approach to synthesizing quinoline and its derivatives. Amongst them MMCF-2 demonstrates significantly enhanced catalytic activity compared with the benchmark MOFs, HKUST-1 and MOF-505, as a result of a high-density of accessible Cu(II) Lewis acid sites and large window size in the cuboctahedral cage-based nanoreactor of MMCF-2.

  1. Accountability in district nursing practice: key concepts.

    Science.gov (United States)

    Griffith, Richard

    2015-03-01

    Public trust and confidence in district nurses is essential to the nurse-patient relationship that underpins effective care and treatment. That trust and confidence has even greater focus for district nurses who care for patients in their own homes. Those patients need to be able to count on the professionalism and probity of their district nurses. The professionalism and probity of district nurses is based on their accountability, which protects the public by imposing standards on district nurses and holds them answerable for their acts and omissions. This is the first of a series of articles on accountability in district nursing practice to mark the introduction of the revised Nursing and Midwifery Code on the 31 March 2015. This month's article considers the key concepts of accountability.

  2. Rehabilitation of district heating networks

    Energy Technology Data Exchange (ETDEWEB)

    Ottosson, Peter [AaF-Energikonsult Syd AB (Sweden)

    1996-11-01

    Often the choice is between reparation or exchange of a damaged section of the network. If the exchange is based on the wrong assumptions, large sections of undamaged pipelines could be removed. Most important for the district heating company is to decide which strategy to use for the future exchange of the pipelines. Whichever strategy used, it has to based on an assessment of the network and/or assumptions based on that assessment. The question if it is possible extend the life span of the pipelines arises. What is the most economical choice, the exchange or the renovation. (au)

  3. A good year for district heating

    International Nuclear Information System (INIS)

    Bakken, Stein Arne

    2003-01-01

    In Norway, high prices on electric power have caused economic progress for the district heating companies. The price of district heating is determined by the prices of power and fuel oil. However, the government wants to remove the tax on electricity to the industry, which is the district heating companies' major group of customers, along with public buildings. This is likely to entail a great loss of income

  4. Thermodynamic calculation of a district energy cycle

    International Nuclear Information System (INIS)

    Hoehlein, B.; Bauer, A.; Kraut, G.; Scherberich, F.D.

    1975-08-01

    This paper presents a calculation model for a nuclear district energy circuit. Such a circuit means the combination of a steam reforming plant with heat supply from a high-temperature nuclear reactor and a methanation plant with heat production for district heating or electricity production. The model comprises thermodynamic calculations for the endothermic methane reforming reaction as well as the exothermic CO-hydrogenation in adiabatic reactors and allows the optimization of the district energy circuit under consideration. (orig.) [de

  5. Elk monitoring in Lewis and Clark National Historical Park: 2008-2012 synthesis report

    Science.gov (United States)

    Griffin, Paul C.; Jenkins, Kurt J.; Cole, Carla; Clatterbuck, Chris; Boetsch, John; Beirne, Katherine

    2014-01-01

    Maintaining elk (Cervus elaphus roosevelti) herds that frequent Lewis and Clark National Historical Park (NHP) is central to the park’s purpose of preserving the historic, cultural, scenic, and natural resources associated with the winter encampment of the Lewis and Clark expedition. Elk were critically important to the Lewis and Clark expedition in providing food and hides that sustained the expedition during the winter of 1805-06 and supplied them for their return east during 1806. Today, elk remain a key component of interpreting the Lewis and Clark story to over 200,000 park visitors each year at the Fort Clatsop visitor center. In 2008, the US Geological Survey (USGS) began collaborating with Lewis and Clark NHP and the NPS North Coast and Cascades Network to develop a protocol for monitoring long-term changes in the magnitude and spatial patterns of elk use within and adjacent to Lewis and Clark NHP (Griffin et al. 2011). Specific objectives of the monitoring program were to measure trends in (1) relative use of the Fort Clatsop unit by elk during winter; (2) the proportion of areas where elk sign is present in the Fort Clatsop unit in winter; and (3) the frequency of elk sightings from roads in and around the Fort Clatsop unit. This report synthesizes the results of the first four years of monitoring elk distribution and use in Lewis and Clark NHP from 2008-2012. We also present data from FY2012 (Appendix 1), in lieu of an annual report for that year. We used fecal pellet group surveys as the cornerstone for monitoring trends in both relative use of the Fort Clatsop Unit by elk and the proportion of areas where elk sign was present at the end of winter. We estimated pellet group density based on data collected from a network of fecal pellet plots distributed systematically throughout the unit. We developed a double observer sampling scheme that enabled us to estimate detection biases and improve the accuracy of pellet group density estimates. We computed

  6. 75 FR 43958 - Turlock Irrigation District and Modesto Irrigation District; Notice of Application for Amendment...

    Science.gov (United States)

    2010-07-27

    ... to the Turlock Irrigation District's Tuolumne Substation; (2) 23-mile-long, 69-kV Don Pedro-Hawkins Line extending from the Don Pedro switchyard to the Turlock Irrigation District's Hawkins Substation...

  7. 7 CFR 920.12 - District.

    Science.gov (United States)

    2010-01-01

    .... (e) District 5 shall include the counties of San Joaquin, Calaveras, Tuolumne, Merced, Stanislaus, Contra Costa, El Dorado, Amador, Sacramento, Alpine, San Francisco, Alameda, San Mateo, Santa Clara...

  8. Reinstating district nursing: A UK perspective.

    Science.gov (United States)

    Morris, Hannah

    2017-09-01

    As policy directives gather pace for service provision to be delivered in primary care, district nursing has not been recognised as a valuable asset to facilitate this agenda. Investment in district nursing and specialist district nursing education has fallen. This is concurrent with an ageing district nursing workforce, a lack of recruitment and growing caseloads, as district nursing adapts to meet the challenges of the complexities of contemporary healthcare in the community. The district nurse role is complex and multifaceted and includes working collaboratively and creatively to coordinate care. Redressing the shortages of specialist district nurse practitioners with increased numbers of health care support workers will not replace the skill, knowledge, experience required to meet the complex care needs of today's society. District nursing needs to be reinstated as the valuable asset it is, through renewed investment in the service, research development and in specialist practice education. To prevent extinction district nurses need to be able to demonstrate and articulate the complexities and dynamisms of the role to reinstate themselves to their commissioners as a valuable asset for contemporary practice that can meet current health and social care needs effectively. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

  9. 4th Generation District Heating (4GDH)

    DEFF Research Database (Denmark)

    Lund, Henrik; Werner, Sven; Wiltshire, Robin

    2014-01-01

    This paper defines the concept of 4th Generation District Heating (4GDH) including the relations to District Cooling and the concepts of smart energy and smart thermal grids. The motive is to identify the future challenges of reaching a future renewable non-fossil heat supply as part...... of the implementation of overall sustainable energy systems. The basic assumption is that district heating and cooling has an important role to play in future sustainable energy systems – including 100 percent renewable energy systems – but the present generation of district heating and cooling technologies will have...

  10. District Fiscal Policy and Student Achievement

    Directory of Open Access Journals (Sweden)

    Gary G. Huang

    2002-09-01

    Full Text Available School restructuring raises questions about the role of school districts in improving student learning. Centralization by state governments and decentralization to individual schools as proposed in systemic reform leave districts' role unsettled. Empirical research on the district role in the context of ongoing reform is inadequate. This analysis of combined data from the NAEP and the Common Core of Data (CCD was intended to address the issue. We analyzed 1990, 1992, and 1996 NAEP 8th grade mathematics national assessment data in combination with CCD data of corresponding years to examine the extent to which student achievement was related to districts' control over instructional expenditure, adjusting for relevant key factors at both district and student levels. Upon sample modification, we used hierarchical linear modeling (HLM to estimate the relationships of student achievement to two district fiscal policy indictors, current expenditure per pupil (CEPP and districts' discretionary rates for instructional expenditure (DDR. Net of relevant district factors, DDR was found unrelated to districts' average 8th grade math performance. The null effect was consistent in the analysis of the combined NAEP-CCD data for 1990, 1992, and 1996. In contrast, CEPP was found related to higher math performance in a modest yet fairly consistent way. Future research may be productive to separately study individual states and integrate the findings onto the national level.

  11. Agricultural Land Use in Ahlat District

    Directory of Open Access Journals (Sweden)

    Necmettin ELMASTAŞ

    2009-12-01

    Full Text Available Ahlat district has suitable topography for growing of agricultural products. Almost half of Ahlat district is suitable for agricultural. Today, 32.7% of the land use in Ahlat is agricultural area. 90% of agricultural area is dry farming area. 10% of agricultural area is irrigated. 60.3%of land use in Ahlat district is pasturage area. The economy of Ahlat is based on agricultural and animal husbandry. Today, agricultural products such as wheat, potato and sugar beet are grown in agricultural areas. Ahlat district has some problems like unplanned production, irrigation and marketing.

  12. Effect of vegetation and surface amelioration on simulated landform evolution of the post-mining landscape at ERA Ranger mine, Northern Territory. Supervising Scientist report 134

    International Nuclear Information System (INIS)

    Evans, K.G.; Saynor, M.J.; House, T.; The University of Newcastle, Callaghan, NSW; Willgoose, G.

    1998-01-01

    The effect of vegetation and surface ripping on evolution of the ERA Ranger Mine (ERARM) post-mining landform was assessed using the SIBERIA landform evolution model. Data were collected from four sites on the waste rock dump at ERARM-(1) the cap site which was unvegetated and unripped with a surface slope of 0.028 m/m; (2) the batter site, surface slope 0.207 rn/m, also unvegetated and unripped but with a covering of coarse rock material; (3) the soil site, surface slope 0.012 m/m, which had ∼90% vegetation cover of low shrubs and grasses and had been topsoiled and surface ripped; and (4) the fire site, surface slope 0.023 m/m, which was topsoiled and ripped and is presently vegetated with well established trees, grasses and shrubs. Natural rainfall events were monitored on the four sites to collect rainfall, runoff and soil loss data to parameterise the SIBERIA sediment discharge equation. The SIBERIA sediment discharge equation was calibrated using output from a sediment transport model of the form T=β 2 S n1 ∫ Q m1 dt, and the DISTFW rainfall-runoff model. Low frequency high intensity events resulted in the greatest soil loss. Therefore, it is important that sediment loss during high intensity events is predicted accurately. Storms with a range of intensities were selected to derive the sediment transport model. DISTFW hydrology model parameters were derived by fitting four monitored events simultaneously. SIBERIA simulations of post-mining rehabilitated landform evolution showed that for the unvegetated and unripped surface, the landform at 1000 y would be dissected by localised erosion valleys (maximum depth = 7 6 m) with deposited fans (maximum depth 14.8 m) at the outlet of the valleys. Simulated valley form has been recognised in nature which indicates that SIBERIA models natural processes efficiently. For the vegetated and ripped condition reduced valley development (maximum 1000 y depth = 2 4 m) and deposition (maximum 1000 y depth = 4.8 m) occurred

  13. Carbonyl Activation by Borane Lewis Acid Complexation: Transition States of H2 Splitting at the Activated Carbonyl Carbon Atom in a Lewis Basic Solvent and the Proton-Transfer Dynamics of the Boroalkoxide Intermediate.

    Science.gov (United States)

    Heshmat, Mojgan; Privalov, Timofei

    2017-07-06

    By using transition-state (TS) calculations, we examined how Lewis acid (LA) complexation activates carbonyl compounds in the context of hydrogenation of carbonyl compounds by H 2 in Lewis basic (ethereal) solvents containing borane LAs of the type (C 6 F 5 ) 3 B. According to our calculations, LA complexation does not activate a ketone sufficiently enough for the direct addition of H 2 to the O=C unsaturated bond; but, calculations indicate a possibly facile heterolytic cleavage of H 2 at the activated and thus sufficiently Lewis acidic carbonyl carbon atom with the assistance of the Lewis basic solvent (i.e., 1,4-dioxane or THF). For the solvent-assisted H 2 splitting at the carbonyl carbon atom of (C 6 F 5 ) 3 B adducts with different ketones, a number of TSs are computed and the obtained results are related to insights from experiment. By using the Born-Oppenheimer molecular dynamics with the DFT for electronic structure calculations, the evolution of the (C 6 F 5 ) 3 B-alkoxide ionic intermediate and the proton transfer to the alkoxide oxygen atom were investigated. The results indicate a plausible hydrogenation mechanism with a LA, that is, (C 6 F 5 ) 3 B, as a catalyst, namely, 1) the step of H 2 cleavage that involves a Lewis basic solvent molecule plus the carbonyl carbon atom of thermodynamically stable and experimentally identifiable (C 6 F 5 ) 3 B-ketone adducts in which (C 6 F 5 ) 3 B is the "Lewis acid promoter", 2) the transfer of the solvent-bound proton to the oxygen atom of the (C 6 F 5 ) 3 B-alkoxide intermediate giving the (C 6 F 5 ) 3 B-alcohol adduct, and 3) the S N 2-style displacement of the alcohol by a ketone or a Lewis basic solvent molecule. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Efectos de inhibidores de colinesterasa en pacientes con enfermedad asociada a cuerpos de Lewy

    Directory of Open Access Journals (Sweden)

    Nilton Custodio

    2008-09-01

    Full Text Available Objetivos: Analizar los efectos de los inhibidores de colinesterasas (ICE donepezilo, rivastigmina y galantamina en el tratamiento de demencia con cuerpos de Lewy (DCL y demencia de la enfermedad de Parkinson (DEP. Diseño: Estudio tipo ensayo abierto. Lugar: Servicio de Neurología, Hospital Militar Central (HMC, y Unidad de Diagnóstico de Deterioro Cognitivo y Prevención de Demencia, Clínica Internacional. Participantes: Pacientes con demencia asociada a cuerpos de Lewy y demencia de la enfermedad de Parkinson. Intervenciones: Las mediciones de eficacia en 33 pacientes con diagnóstico de DCL y DEP se realizó con el Mini-Mental State Examination (MMSE, Alzheimer Disease Assessment Scale cognitive subscale (ADAS-cog, Alzheimer’s Disease Cooperative Study-Clinical Global Impression of Change (ADCS-CGIC, Alzheimer’s Disease Cooperative Study-Activities of Daily Living Inventory (ADCS-ADL, Neuro-Psychiatry Inventory (NPI, Prueba de dibujo de Reloj de Manos (PDR-M y la Unified Parkinson´s Disease Rating Scale-motor subscale (UPDRS-part III. Principales medidas de resultados: Síntomas cognitivos, funcionamiento global y actividades de vida diaria de los pacientes. Resultados: Diecisiete pacientes fueron tratados con rivastigmina, 9 con galantamina y 7 con donepezilo. Luego de 6 meses de tratamiento, los pacientes en tratamiento con rivastigmina mejoraron en 1,39 puntos en ADAS-cog respecto de su medición basal, mientras que los pacientes tratados con donepezilo y galantamina no mostraron cambios (cambios <0,2 puntos. Respecto al ADCS-ADL, los pacientes tratados con rivastigmina, donepezilo y galantamina demostraron disminución de 0,42, 0,58 y 0,75 puntos, respectivamente. En el MMSE, los pacientes tratados con rivastigmina y donepezilo no mostraron cambios y los pacientes tratados con galantamina tuvieron una disminución promedio de 1,19 puntos. No hubo diferencias significativas en la incidencia de síntomas parkinsonianos en los tres

  15. Uranium districts in South Greenland

    International Nuclear Information System (INIS)

    Armour-Brown, A.; Tukiainen, T.; Wallin, B.

    1981-01-01

    A short review is given of reconnaissance work in South Greenland. The work has demonstrated that there are areas in the Motzfeldt centre of at least 1 km 2 with continuously high radioactivity. If the uranium content of these radioactive zones are sufficiently high, then potential ore tonnages could prove to be substantial. The reconnaissance exploration has proved that uranium mineralization is widely distributed in the Narssaq-Narssarssuaq district. It is, no doubt, responsible for the high uranium values in the exploration geochemical samples. Although the size of the pitchblende occurences which have been found so far are small, the high grade of the mineralisation, the great frequency of the fracturing and the evidence for an all pervasive mineralising event over a wide area indicate that there is a good possibility of finding economic mineralisation within the Narssaq-Narssarssuaq area. The area as a whole may, perhaps, be termed a ''uranium mineral district''. As the potential targets are small, only detailed follow-up exploration will establish this. At the same time more detailed work on individual showings, and geological mapping to demonstrate the relative ages of the various petrological and mineralising events, will establish the possible origin of this uranium mineralisation. (author)

  16. Budget Stability, Revenue Volatility, and District Relations: Determinants of Georgia ELOST Distribution to Municipal School Districts

    Science.gov (United States)

    Reinagel, Tyler P.

    2014-01-01

    School districts across the United States are often forced into situations where limited public funds must be distributed among multiple districts. These are often reliant on distribution rates negotiated by district leadership and elected officials. An example of this is Georgia's 1% Education Local Option Sales Tax (ELOST). The tax is collected…

  17. Revisiting "Rodriguez v. Los Angeles Unified School District": A Case of Intra-District Inequities

    Science.gov (United States)

    Espinosa, Ruben W.

    2010-01-01

    The educational community and the courts continue to struggle with the challenges of intra-district resource inequality revealed by the California Supreme Court landmark case "Rodriguez v. Los Angeles Unified School District" (1992). Intra-district school resource inequality is one of the remaining bastions of major inequalities in the…

  18. 77 FR 63326 - Huron Wetland Management District, Madison Wetland Management District, and Sand Lake Wetland...

    Science.gov (United States)

    2012-10-16

    ..., consistent with sound principles of fish and wildlife management, conservation, legal mandates, and our... FXRS1265066CCP0] Huron Wetland Management District, Madison Wetland Management District, and Sand Lake Wetland Management District, SD; Final Comprehensive Conservation Plan and Finding of No Significant Impact for...

  19. 33 CFR 3.25-1 - Fifth district.

    Science.gov (United States)

    2010-07-01

    ... District § 3.25-1 Fifth district. (a) The District Office is in Portsmouth, Va. (b) The Fifth Coast Guard District is comprised of: North Carolina; Virginia; District of Columbia; Maryland; Delaware; that part of... boundary at the shoreline at the North Carolina-South Carolina border, point located at approximately 30°55...

  20. Differential impact of stress on hypothalamic–pituitary–adrenal axis: Gene expression changes in Lewis and Fisher rats

    Czech Academy of Sciences Publication Activity Database

    Ergang, Peter; Vodička, Martin; Soták, Matúš; Klusoňová, Petra; Behuliak, Michal; Řeháková, Lenka; Zach, P.; Pácha, Jiří

    2015-01-01

    Roč. 53, Mar 2015 (2015), s. 49-59 ISSN 0306-4530 R&D Projects: GA ČR(CZ) GAP303/10/0969 Institutional support: RVO:67985823 Keywords : 11beta-hydroxysteroid dehydrogenase type 1 * brain * neuropeptides * stress * Fisher rat * Lewis rat Subject RIV: ED - Physiology Impact factor: 4.704, year: 2015