WorldWideScience

Sample records for range research laboratory

  1. The National Fire Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The National Fire Research Laboratory (NFRL) is adding a unique facility that will serve as a center of excellence for fireperformance of structures ranging in size...

  2. Combustion Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Combustion Research Laboratory facilitates the development of new combustion systems or improves the operation of existing systems to meet the Army's mission for...

  3. Aquatic Research Laboratory (ARL)

    Data.gov (United States)

    Federal Laboratory Consortium — Columbia River and groundwater well water sources are delivered to the Aquatic Research Laboratory (ARL), where these resources are used to conduct research on fish...

  4. Energy Materials Research Laboratory (EMRL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Energy Materials Research Laboratory at the Savannah River National Laboratory (SRNL) creates a cross-disciplinary laboratory facility that lends itself to the...

  5. Simula Research Laboratory

    CERN Document Server

    Tveito, Aslak

    2010-01-01

    The Simula Research Laboratory, located just outside Oslo in Norway, is rightly famed as a highly successful research facility, despite being, at only eight years old, a very young institution. This fascinating book tells the history of Simula, detailing the culture and values that have been the guiding principles of the laboratory throughout its existence. Dedicated to tackling scientific challenges of genuine social importance, the laboratory undertakes important research with long-term implications in networks, computing and software engineering, including specialist work in biomedical comp

  6. Green Building Research Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Sailor, David Jean [Portland State Univ., Portland, OR (United States)

    2013-12-29

    This project provided support to the Green Building Research Laboratory at Portland State University (PSU) so it could work with researchers and industry to solve technical problems for the benefit of the green building industry. It also helped to facilitate the development of PSU’s undergraduate and graduate-level training in building science across the curriculum.

  7. Korogwe Research Laboratory

    DEFF Research Database (Denmark)

    Knudsen, Jakob

    2012-01-01

    Scientist has for decades struggled to develop a safe vaccine to prevent malaria, a disease killing hundreds of thousands of peoples every year, mostly small children and pregnant women. The Korogwe Research Laboratory is erected to provide modern facilities for the test of a new malaria vaccine...... and materials have been carefully selected to last a long time even in a future situation with limited maintenance. Except from the high-end lab equipment only local available materials have been used. All major spaces are reached from colonnades surrounding an inner calm and cool garden space equipped...

  8. Materials Behavior Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The purpose is to evaluate mechanical properties of materials including metals, intermetallics, metal-matrix composites, and ceramic-matrix composites under typical...

  9. Laboratory for Large Data Research

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: The Laboratory for Large Data Research (LDR) addresses a critical need to rapidly prototype shared, unified access to large amounts of data across both the...

  10. Geocentrifuge Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The geocentrifuge subjects a sample to a high-gravity field by spinning it rapidly around a central shaft. In this high-gravity field, processes, such as fluid flow,...

  11. Physical Research Laboratory

    Indian Academy of Sciences (India)

    INF. & ANN. Non-linear Dynamics, Computational Physics and Computer Science. Classical and quantum chaos and time series analysis of complex systems. Numerical studies in general relativity. Research in computer science with focus on image processing and pattern recognition. Laser Physics and Quantum Optics.

  12. Research System Integration Laboratory (SIL)

    Data.gov (United States)

    Federal Laboratory Consortium — The VEA Research SIL (VRS) is essential to the success of the TARDEC 30-Year Strategy. The vast majority of the TARDEC Capability Sets face challenging electronics...

  13. Commissioning a materials research laboratory

    Energy Technology Data Exchange (ETDEWEB)

    SAVAGE,GERALD A.

    2000-03-28

    This presentation covers the process of commissioning a new 150,000 sq. ft. research facility at Sandia National Laboratories. The laboratory being constructed is a showcase of modern design methods being built at a construction cost of less than $180 per sq. ft. This is possible in part because of the total commissioning activities that are being utilized for this project. The laboratory's unique approach to commissioning will be presented in this paper. The process will be followed through from the conceptual stage on into the actual construction portion of the laboratory. Lessons learned and cost effectiveness will be presented in a manner that will be usable for others making commissioning related decisions. Commissioning activities at every stage of the design will be presented along with the attributed benefits. Attendees will hear answers to the what, when, who, and why questions associated with commissioning of this exciting project.

  14. SESAME/Environmental Research Laboratories

    Science.gov (United States)

    1977-01-01

    The Environmental Research Laboratories (ERL) have been designated as the basic research group of the National Oceanic and Atmospheric Administration (NOAA). ERL performs an integrated program of research and research services directed toward understanding the geophysical environment, protecting the environment, and improving the forecasting ability of NOAA. Twenty-four laboratories located throughout the United States comprise ERL. The Project SESAME (Severe Environmental Storms and Mesoscale Experiment) Planning Office is a project office within ERL. SESAME is conceived as a joint effort involving NOAA, NASA, NSF, and the atmospheric science community to lay the foundation for improved prediction of severe convective storms. The scientific plan for SESAME includes a phased buildup of analysis, modeling, instrumentation development and procurement, and limited-scale observational activities.

  15. Stirling Laboratory Research Engine: Preprototype configuration report

    Science.gov (United States)

    Hoehn, F. W.

    1982-02-01

    The concept of a simple Stirling research engine that could be used by industrial, university, and government laboratories was studied. The conceptual and final designs, hardware fabrication and the experimental validation of a preprototype stirling laboratory research engine (SLRE) were completed. Also completed was a task to identify the potential markets for research engines of this type. An analytical effort was conducted to provide a stirling cycle computer model. The versatile engine is a horizontally opposed, two piston, single acting stirling engine with a split crankshaft drive mechanism; special instrumentation is installed at all component interfaces. Results of a thermodynamic energy balance for the system are reported. Also included are the engine performance results obtained over a range of speeds, working pressures, phase angles and gas temperatures. The potential for a stirling research engine to support the laboratory requirements of educators and researchers was demonstrated.

  16. Small-Engine Research Laboratory (SERL)

    Data.gov (United States)

    Federal Laboratory Consortium — Description: The Small-Engine Research Laboratory (SERL) is a facility designed to conduct experimental small-scale propulsion and power generation systems research....

  17. Laboratory directed research and development

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-15

    The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory's R D capabilities, and further the development of its strategic initiatives. Among the aims of the projects supported by the Program are establishment of engineering proof-of-principle''; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these project are closely associated with major strategic thrusts of the Laboratory as described in Argonne's Five Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne. Areas of emphasis are (1) advanced accelerator and detector technology, (2) x-ray techniques in biological and physical sciences, (3) advanced reactor technology, (4) materials science, computational science, biological sciences and environmental sciences. Individual reports summarizing the purpose, approach, and results of projects are presented.

  18. NAS Human Factors Safety Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory conducts an integrated program of research on the relationship of factors concerning individuals, work groups, and organizations as employees perform...

  19. NDE Acoustic Microscopy Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The purpose is to develop advanced, more effective high-resolution micro-NDE materials characterization methods using scanning acoustic microscopy. The laboratory's...

  20. Photobiology Research Laboratory (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2012-06-01

    This fact sheet provides information about Photobiology Research Laboratory capabilities and applications at NREL. The photobiology group's research is in four main areas: (1) Comprehensive studies of fuel-producing photosynthetic, fermentative, and chemolithotrophic model microorganisms; (2) Characterization and engineering of redox enzymes and proteins for fuel production; (3) Genetic and pathway engineering of model organisms to improve production of hydrogen and hydrocarbon fuels; and (4) Studies of nanosystems using biological and non-biological materials in hybrid generation. NREL's photobiology research capabilities include: (1) Controlled and automated photobioreactors and fermenters for growing microorganisms under a variety of environmental conditions; (2) High-and medium-throughput screening of H{sub 2}-producing organisms; (3) Homologous and heterologous expression, purification, and biochemical/biophysical characterization of redox enzymes and proteins; (4) Qualitative and quantitative analyses of gases, metabolites, carbohydrates, lipids, and proteins; (5) Genetic and pathway engineering and development of novel genetic toolboxes; and (6) Design and spectroscopic characterization of enzyme-based biofuel cells and energy conversion nanodevices.

  1. Unbridle biomedical research from the laboratory cage.

    Science.gov (United States)

    Lahvis, Garet P

    2017-06-29

    Many biomedical research studies use captive animals to model human health and disease. However, a surprising number of studies show that the biological systems of animals living in standard laboratory housing are abnormal. To make animal studies more relevant to human health, research animals should live in the wild or be able to roam free in captive environments that offer a natural range of both positive and negative experiences. Recent technological advances now allow us to study freely roaming animals and we should make use of them.

  2. Artificial Intelligence Research at GTE Laboratories (Research in Progress)

    OpenAIRE

    Frawley, William; Goyal, Shri

    1984-01-01

    GTE Laboratories is the central corporate research and development facility for the sixty subsidiaries of the worldwide GTE corporation. Located in the Massachusetts Route 128 high technology area, the five laboratories that comprise GTE Laboratories generate the ideas, products, systems, and services that provide technical leadership for GTE. The two laboratories which conduct artificial intelligence research are the Computer Science Laboratory (CSL) and the Fundamental Research Laboratory (...

  3. Range management research, Fort Valley Experimental Forest

    Science.gov (United States)

    Henry A. Pearson; Warren P. Clary; Margaret M. Moore; Carolyn Hull Sieg

    2008-01-01

    Range management research at the Fort Valley Experimental Forest during the past 100 years has provided scientific knowledge for managing ponderosa pine forests and forest-range grazing lands in the Southwest. Three research time periods are identified: 1908 to 1950, 1950 to 1978, and 1978 to 2008. Early research (1908-1950) addressed ecological effects of livestock...

  4. Air Force Research Laboratory Cryocooler Technology Development

    Science.gov (United States)

    Davis, Thomas M.; Smith, D. Adam; Easton, Ryan M.

    2004-06-01

    This paper presents an overview of the cryogenic refrigerator and cryogenic integration programs in development and characterization under the Cryogenic Cooling Technology Group, Space Vehicles Directorate of the Air Force Research Laboratory (AFRL). The vision statement for the group is to support the space community as the center of excellence for developing and transitioning space cryogenic thermal management technologies. This paper will describe the range of Stirling, pulse tube; reverse Brayton, and Joule-Thomson cycle cryocoolers currently under development to meet current and future Air Force and Department of Defense requirements. Cooling requirements at 10K, 35K, 60K, 95K, and multistage cooling requirements at 35/85K are addressed. In order to meet these various requirements, the Air Force Research Laboratory, Space Vehicles Directorate is pursuing various strategic cryocooler and cryogenic integration options. The Air Force Research Laboratory, working with industry partners, is also developing several advanced cryogenic integration technologies that will result in the reduction in current cryogenic system integration penalties and design time. These technologies include the continued development of gimbaled transport systems, 35K and 10K thermal storage units, heat pipes, cryogenic straps, and thermal switches.

  5. Biometrics Research and Engineering Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — As the Department of Defense moves forward in its pursuit of integrating biometrics technology into facility access control, the Global War on Terrorism and weapon...

  6. Subsonic Aerodynamic Research Laboratory (SARL)

    Data.gov (United States)

    Federal Laboratory Consortium — Description: The SARL is a unique high contraction, open circuit subsonic wind tunnel providing a test velocity up to 436 mph (0.5 Mach number) and a high quality,...

  7. RANGE ECONOMICS RESEARCH (THE NATIONAL INTEREST)

    OpenAIRE

    Crom, Richard J.

    1985-01-01

    Increasing interest in range economics research calls for a more tightly defined set of issues and a menu of research projects addressing these issues. This paper identifies major issues of national importance followed by a brief description of suggested research projects.

  8. Cookstove Laboratory Research - Fiscal Year 2016 Report

    Science.gov (United States)

    This report provides an overview of the work conducted by the EPA cookstove laboratory research team in Fiscal Year 2016. The report describes research and activities including (1) ISO standards development, (2) capacity building for international testing and knowledge centers, ...

  9. Archive and laboratory embedded in the landscape: Future of the Santa Rita Experimental Range

    Science.gov (United States)

    Thomas E. Sheridan

    2003-01-01

    The Santa Rita Experimental Range (SRER) is both an archive of past ecological research and a laboratory for continuing research embedded in the southern Arizona landscape. The scientific questions being asked there have changed over the last 100 years, but SRER with its monitoring stations and its legacy of repeat photography still offers a unique opportunity to study...

  10. Short range radio research in Twente

    NARCIS (Netherlands)

    Meijerink, Arjan

    2010-01-01

    The research and education by the Telecommunication Engineering Group at the University of Twente is dedicated to physical layer topics in communications. Three research tracks have prominence: Short Range Radio, Microwave Photonics, and Electromagnetic Compatibility. Arjan is active in the Short

  11. Laboratory Directed Research and Development FY 1992

    Energy Technology Data Exchange (ETDEWEB)

    Struble, G.L.; Middleton, C.; Anderson, S.E.; Baldwin, G.; Cherniak, J.C.; Corey, C.W.; Kirvel, R.D.; McElroy, L.A. [eds.

    1992-12-31

    The Laboratory Directed Research and Development (LDRD) Program at Lawrence Livermore National Laboratory (LLNL) funds projects that nurture and enrich the core competencies of the Laboratory. The scientific and technical output from the FY 1992 RD Program has been significant. Highlights include (1) Creating the first laser guide star to be coupled with adaptive optics, thus permitting ground-based telescopes to obtain the same resolution as smaller space-based instruments but with more light-gathering power. (2) Significantly improving the limit on the mass of the electron antineutrino so that neutrinos now become a useful tool in diagnosing supernovas and we disproved the existence of a 17-keV neutrino. (3) Developing a new class of organic aerogels that have robust mechanical properties and that have significantly lower thermal conductivity than inorganic aerogels. (4) Developing a new heavy-ion accelerator concept, which may enable us to design heavy-ion experimental systems and use a heavy-ion driver for inertial fusion. (5) Designing and demonstrating a high-power, diode-pumped, solid-state laser concept that will allow us to pursue a variety of research projects, including laser material processing. (6) Demonstrating that high-performance semiconductor arrays can be fabricated more efficiently, which will make this technology available to a broad range of applications such as inertial confinement fusion for civilian power. (7) Developing a new type of fiber channel switch and new fiber channel standards for use in local- and wide-area networks, which will allow scientists and engineers to transfer data at gigabit rates. (8) Developing the nation`s only numerical model for high-technology air filtration systems. Filter designs that use this model will provide safer and cleaner environments in work areas where contamination with particulate hazardous materials is possible.

  12. Naval Research Laboratory 1986 Review

    Science.gov (United States)

    1986-01-01

    the characteristic R\\ , nmc 66. 530-535 1986). M emission of C, and OH in these studies. In these 2C 78 •~~~~ ~J P r * .CHEMICAL RESEARCH S I I 6 I...Application in Un- Relative Entropy , Probabilistic Inference and derwater Transducers, by Rittenmyer Al, by Shore, J.E., Artificial Intelligence, K.M...an Elastic Earth. by Maximum Entropy and Reliability Distribu- Lanzano. P.. Earth, Moon. and Planets tion, by Teitler, S , Rajagopal, A.K., and 36

  13. Laboratory Technology Research: Abstracts of FY 1996 projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of this country: the world-class basic research capability of the DOE Energy Research (ER) multi-program national laboratories and the unparalleled entrepreneurial spirit of American industry. Projects supported by the LTR program are conducted by the five ER multi-program laboratories: Argonne, Brookhaven, Lawrence Berkeley, Oak Ridge, and Pacific Northwest National Laboratories. These projects explore the applications of basic research advances relevant to Department of Energy`s (DOE) mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials, intelligent processing/manufacturing research, and sustainable environments.

  14. Crime Laboratory Proficiency Testing Research Program.

    Science.gov (United States)

    Peterson, Joseph L.; And Others

    A three-year research effort was conducted to design a crime laboratory proficiency testing program encompassing the United States. The objectives were to: (1) determine the feasibility of preparation and distribution of different classes of physical evidence; (2) assess the accuracy of criminalistics laboratories in the processing of selected…

  15. Cyber Defense Research and Monitoring Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This facility acts as a fusion point for bridging ARL's research in tactical and operational Information Assurance (IA) areas and the development and assessment of...

  16. Using a research laboratory for training students

    Science.gov (United States)

    Consortini, Anna

    2007-06-01

    We present a way to use a Research Laboratory for training students to learn about simple measurements. In most cases, doing research and training students imply conflicting requirements, for instance in a Research Laboratory everything is aligned, some equipment cannot be moved and so on; therefore research and training laboratories are separated. Sometimes however, there is the possibility of using a part or the complete research equipment by the students, without "consequences". As an example, here we describe the way we used a research set up of wave propagation through atmospheric turbulence, devoted to long lasting statistical measurements, to train students in making position measurements and experiments at different levels, starting from beginners up to advanced and PhD students.

  17. Laboratory Learning in a Research Methods Course

    Directory of Open Access Journals (Sweden)

    Sarah Knapp

    2016-03-01

    Full Text Available Laboratory-based learning is increasingly considered to be an integral component of undergraduate education. However, students do not always perceive the value of laboratory learning in the college classroom. The current research sought to create an effective laboratory learning environment within a research methods course and to assess students’ perceptions of this approach at the end of one semester. This article reports the findings for two studies; in Study 1, a survey was given to 17 criminal justice, health care management and advocacy, and psychology students. In a subsequent semester, challenges from Study 1 were addressed, and the same survey (i.e., Study 2 was given to 20 criminal justice and psychology majors. Across both samples, students’ responses to the laboratory learning paradigm were generally positive, yet concerns and challenges were identified. Future research should attempt to address these concerns and to assess objective student outcomes, such as grades in the course.

  18. Chemical research at Argonne National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    Argonne National Laboratory is a research and development laboratory located 25 miles southwest of Chicago, Illinois. It has more than 200 programs in basic and applied sciences and an Industrial Technology Development Center to help move its technologies to the industrial sector. At Argonne, basic energy research is supported by applied research in diverse areas such as biology and biomedicine, energy conservation, fossil and nuclear fuels, environmental science, and parallel computer architectures. These capabilities translate into technological expertise in energy production and use, advanced materials and manufacturing processes, and waste minimization and environmental remediation, which can be shared with the industrial sector. The Laboratory`s technologies can be applied to help companies design products, substitute materials, devise innovative industrial processes, develop advanced quality control systems and instrumentation, and address environmental concerns. The latest techniques and facilities, including those involving modeling, simulation, and high-performance computing, are available to industry and academia. At Argonne, there are opportunities for industry to carry out cooperative research, license inventions, exchange technical personnel, use unique research facilities, and attend conferences and workshops. Technology transfer is one of the Laboratory`s major missions. High priority is given to strengthening U.S. technological competitiveness through research and development partnerships with industry that capitalize on Argonne`s expertise and facilities. The Laboratory is one of three DOE superconductivity technology centers, focusing on manufacturing technology for high-temperature superconducting wires, motors, bearings, and connecting leads. Argonne National Laboratory is operated by the University of Chicago for the U.S. Department of Energy.

  19. NASA Ames Fluid Mechanics Laboratory research briefs

    Science.gov (United States)

    Davis, Sanford (Editor)

    1994-01-01

    The Ames Fluid Mechanics Laboratory research program is presented in a series of research briefs. Nineteen projects covering aeronautical fluid mechanics and related areas are discussed and augmented with the publication and presentation output of the Branch for the period 1990-1993.

  20. National Reference Laboratories RIKILT Wageningen University & Research

    NARCIS (Netherlands)

    Leeuwen, van S.P.J.; Mol, J.G.J.; Lee, van der M.K.; Gerssen, A.; Lasaroms, J.J.P.; Sterk, S.S.; Raamsdonk, van L.W.D.; Jong, de J.; Scholtens-Toma, I.M.J.; Alewijn, M.; Weesepoel, Y.J.A.; Ginkel, van L.A.; Meijer, Nathan; Noordam, M.Y.

    2017-01-01

    National Reference Laboratories (NRLs) are part of the system responsible for the control and enforcement of EU food and feed law. RIKILT Wageningen University & Research has been designated as the NRL for twelve subjects. The tasks of a NRL depend on its research field. This report gives an

  1. 1999 LDRD Laboratory Directed Research and Development

    Energy Technology Data Exchange (ETDEWEB)

    Rita Spencer; Kyle Wheeler

    2000-06-01

    This is the FY 1999 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5) engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.

  2. Idaho National Laboratory Research & Development Impacts

    Energy Technology Data Exchange (ETDEWEB)

    Stricker, Nicole [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-01-01

    Technological advances that drive economic growth require both public and private investment. The U.S. Department of Energy’s national laboratories play a crucial role by conducting the type of research, testing and evaluation that is beyond the scope of regulators, academia or industry. Examples of such work from the past year can be found in these pages. Idaho National Laboratory’s engineering and applied science expertise helps deploy new technologies for nuclear energy, national security and new energy resources. Unique infrastructure, nuclear material inventory and vast expertise converge at INL, the nation’s nuclear energy laboratory. Productive partnerships with academia, industry and government agencies deliver high-impact outcomes. This edition of INL’s Impacts magazine highlights national and regional leadership efforts, growing capabilities, notable collaborations, and technology innovations. Please take a few minutes to learn more about the critical resources and transformative research at one of the nation’s premier applied science laboratories.

  3. National Renewable Energy Laboratory 2004 Research Review

    Energy Technology Data Exchange (ETDEWEB)

    2005-03-01

    In-depth articles on several NREL technologies and advances, including: aligning quantum dots and related nanoscience and nanotechnology research; using NREL's Advanced Automotive Manikin (ADAM) to help test and design ancillary automotive systems; and harvesting ocean wind to generate electricity with deep-water wind turbines. Also covered are NREL news, research updates, and awards and honors received by the Laboratory.

  4. Adult Hematology and Clinical Chemistry Laboratory Reference Ranges in a Zimbabwean Population.

    Directory of Open Access Journals (Sweden)

    Wadzanai P Samaneka

    Full Text Available Laboratory reference ranges used for clinical care and clinical trials in various laboratories in Zimbabwe were derived from textbooks and research studies conducted more than ten years ago. Periodic verification of these ranges is essential to track changes over time. The purpose of this study was to establish hematology and chemistry laboratory reference ranges using more rigorous methods.A community-based cross-sectional study was carried out in Harare, Chitungwiza, and Mutoko. A multistage sampling technique was used. Samples were transported from the field for analysis at the ISO15189 certified University of Zimbabwe-University of California San Francisco Central Research Laboratory. Hematology and clinical chemistry reference ranges lower and upper reference limits were estimated at the 2.5th and 97.5th percentiles respectively.A total of 769 adults (54% males aged 18 to 55 years were included in the analysis. Median age was 28 [IQR: 23-35] years. Males had significantly higher red cell counts, hemoglobin, hematocrit, and mean corpuscular hemoglobin compared to females. Females had higher white cell counts, platelets, absolute neutrophil counts, and absolute lymphocyte counts compared to males. There were no gender differences in eosinophils, monocytes, and absolute basophil count. Males had significantly higher levels of urea, sodium, potassium, calcium, creatinine, amylase, total protein, albumin and liver enzymes levels compared to females. Females had higher cholesterol and lipase compared with males. There are notable differences in the white cell counts, neutrophils, cholesterol, and creatinine kinase when compared with the currently used reference ranges.Data from this study provides new country specific reference ranges which should be immediately adopted for routine clinical care and accurate monitoring of adverse events in research studies.

  5. Adult Hematology and Clinical Chemistry Laboratory Reference Ranges in a Zimbabwean Population.

    Science.gov (United States)

    Samaneka, Wadzanai P; Mandozana, Gibson; Tinago, Willard; Nhando, Nehemiah; Mgodi, Nyaradzo M; Bwakura-Dangarembizi, Mutsawashe F; Munjoma, Marshall W; Gomo, Zvenyika A R; Chirenje, Zvavahera M; Hakim, James G

    2016-01-01

    Laboratory reference ranges used for clinical care and clinical trials in various laboratories in Zimbabwe were derived from textbooks and research studies conducted more than ten years ago. Periodic verification of these ranges is essential to track changes over time. The purpose of this study was to establish hematology and chemistry laboratory reference ranges using more rigorous methods. A community-based cross-sectional study was carried out in Harare, Chitungwiza, and Mutoko. A multistage sampling technique was used. Samples were transported from the field for analysis at the ISO15189 certified University of Zimbabwe-University of California San Francisco Central Research Laboratory. Hematology and clinical chemistry reference ranges lower and upper reference limits were estimated at the 2.5th and 97.5th percentiles respectively. A total of 769 adults (54% males) aged 18 to 55 years were included in the analysis. Median age was 28 [IQR: 23-35] years. Males had significantly higher red cell counts, hemoglobin, hematocrit, and mean corpuscular hemoglobin compared to females. Females had higher white cell counts, platelets, absolute neutrophil counts, and absolute lymphocyte counts compared to males. There were no gender differences in eosinophils, monocytes, and absolute basophil count. Males had significantly higher levels of urea, sodium, potassium, calcium, creatinine, amylase, total protein, albumin and liver enzymes levels compared to females. Females had higher cholesterol and lipase compared with males. There are notable differences in the white cell counts, neutrophils, cholesterol, and creatinine kinase when compared with the currently used reference ranges. Data from this study provides new country specific reference ranges which should be immediately adopted for routine clinical care and accurate monitoring of adverse events in research studies.

  6. Laboratory Directed Research and Development Program

    Energy Technology Data Exchange (ETDEWEB)

    Ogeka, G.J.

    1991-12-01

    Today, new ideas and opportunities, fostering the advancement of technology, are occurring at an ever-increasing rate. It, therefore, seems appropriate that a vehicle be available which fosters the development of these new ideas and technologies, promotes the early exploration and exploitation of creative and innovative concepts, and which develops new fundable'' R D projects and programs. At Brookhaven National Laboratory (BNL), one such method is through its Laboratory Directed Research and Development (LDRD) Program. This discretionary research and development tool is critical in maintaining the scientific excellence and vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor achieving and maintaining staff excellence, and a means to address national needs, with the overall mission of the Department of Energy (DOE) and the Brookhaven National Laboratory. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, they have resulted in numerous publications in various professional and scientific journals, and presentations at meetings and forums.

  7. Tonopah test range - outpost of Sandia National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, L.

    1996-03-01

    Tonopah Test Range is a unique historic site. Established in 1957 by Sandia Corporation, Tonopah Test Range in Nevada provided an isolated place for the Atomic Energy Commission to test ballistics and non-nuclear features of atomic weapons. It served this and allied purposes well for nearly forty years, contributing immeasurably to a peaceful conclusion to the long arms race remembered as the Cold War. This report is a brief review of historical highlights at Tonopah Test Range. Sandia`s Los Lunas, Salton Sea, Kauai, and Edgewood testing ranges also receive abridged mention. Although Sandia`s test ranges are the subject, the central focus is on the people who managed and operated the range. Comments from historical figures are interspersed through the narrative to establish this perspective, and at the end a few observations concerning the range`s future are provided.

  8. The Johns Hopkins Hunterian Laboratory Philosophy: Mentoring Students in a Scientific Neurosurgical Research Laboratory.

    Science.gov (United States)

    Tyler, Betty M; Liu, Ann; Sankey, Eric W; Mangraviti, Antonella; Barone, Michael A; Brem, Henry

    2016-06-01

    After over 50 years of scientific contribution under the leadership of Harvey Cushing and later Walter Dandy, the Johns Hopkins Hunterian Laboratory entered a period of dormancy between the 1960s and early 1980s. In 1984, Henry Brem reinstituted the Hunterian Neurosurgical Laboratory, with a new focus on localized delivery of therapies for brain tumors, leading to several discoveries such as new antiangiogenic agents and Gliadel chemotherapy wafers for the treatment of malignant gliomas. Since that time, it has been the training ground for 310 trainees who have dedicated their time to scientific exploration in the lab, resulting in numerous discoveries in the area of neurosurgical research. The Hunterian Neurosurgical Laboratory has been a unique example of successful mentoring in a translational research environment. The laboratory's philosophy emphasizes mentorship, independence, self-directed learning, creativity, and people-centered collaboration, while maintaining productivity with a focus on improving clinical outcomes. This focus has been served by the diverse backgrounds of its trainees, both in regard to educational status as well as culturally. Through this philosophy and strong legacy of scientific contribution, the Hunterian Laboratory has maintained a positive and productive research environment that supports highly motivated students and trainees. In this article, the authors discuss the laboratory's training philosophy, linked to the principles of adult learning (andragogy), as well as the successes and the limitations of including a wide educational range of students in a neurosurgical translational laboratory and the phenomenon of combining clinical expertise with rigorous scientific training.

  9. Laboratory technology research: Abstracts of FY 1998 projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of the country: the world-class basic research capability of the DOE Office of Science (SC) national laboratories and the unparalleled entrepreneurial spirit of American industry. Projects supported by the LTR program in FY 1998 explore the applications of basic research advances relevant to DOE`s mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials, intelligent processing and manufacturing research, and environmental and biomedical research. Abstracts for 85 projects are contained in this report.

  10. Laboratory Directed Research and Development FY 2000

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd; Levy, Karin

    2001-02-27

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Annual report on Laboratory Directed Research and Development for FY2000.

  11. Laboratory technology research - abstracts of FY 1997 projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of this country: the world-class basic research capability of the DOE Energy Research (ER) multi-program national laboratories and the unparalleled entrepreneurial spirit of American industry. A distinguishing feature of the ER multi-program national laboratories is their ability to integrate broad areas of science and engineering in support of national research and development goals. The LTR program leverages this strength for the Nation`s benefit by fostering partnerships with US industry. The partners jointly bring technology research to a point where industry or the Department`s technology development programs can pursue final development and commercialization. Projects supported by the LTR program are conducted by the five ER multi-program laboratories. These projects explore the applications of basic research advances relevant to DOE`s mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials; intelligent processing/manufacturing research; and sustainable environments.

  12. National Renewable Energy Laboratory 2003 Research Review

    Energy Technology Data Exchange (ETDEWEB)

    2004-04-01

    In-depth articles on several NREL technologies and advances, including: production of hydrogen using renewable resources and technologies; use of carbon nanotubes for storing hydrogen; enzymatic reduction of cellulose to simple sugars as a platform for making fuel, chemicals, and materials; and the potential of electricity from wind energy to offset carbon dioxide emissions. Also covered are NREL news, awards and honors received by the Laboratory, and patents granted to NREL researchers.

  13. Reference ranges for the clinical laboratory derived from a rural population in Kericho, Kenya.

    Directory of Open Access Journals (Sweden)

    Rukia S Kibaya

    Full Text Available The conduct of Phase I/II HIV vaccine trials internationally necessitates the development of region-specific clinical reference ranges for trial enrollment and participant monitoring. A population based cohort of adults in Kericho, Kenya, a potential vaccine trial site, allowed development of clinical laboratory reference ranges. Lymphocyte immunophenotyping was performed on 1293 HIV seronegative study participants. Hematology and clinical chemistry were performed on up to 1541 cohort enrollees. The ratio of males to females was 1.9:1. Means, medians and 95% reference ranges were calculated and compared with those from other nations. The median CD4+ T cell count for the group was 810 cells/microl. There were significant gender differences for both red and white blood cell parameters. Kenyan subjects had lower median hemoglobin concentrations (9.5 g/dL; range 6.7-11.1 and neutrophil counts (1850 cells/microl; range 914-4715 compared to North Americans. Kenyan clinical chemistry reference ranges were comparable to those from the USA, with the exception of the upper limits for bilirubin and blood urea nitrogen, which were 2.3-fold higher and 1.5-fold lower, respectively. This study is the first to assess clinical reference ranges for a highland community in Kenya and highlights the need to define clinical laboratory ranges from the national community not only for clinical research but also care and treatment.

  14. MSU-DOE Plant Research Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    This document is the compiled progress reports of research funded through the Michigan State University/Department of Energy Plant Research Laboratory. Fourteen reports are included, covering the molecular basis of plant/microbe symbiosis, cell wall biosynthesis and proteins, gene expression, stress responses, plant hormone biosynthesis, interactions between the nuclear and organelle genomes, sensory transduction and tropisms, intracellular sorting and trafficking, regulation of lipid metabolism, molecular basis of disease resistance and plant pathogenesis, developmental biology of Cyanobacteria, and hormonal involvement in environmental control of plant growth. 320 refs., 26 figs., 3 tabs. (MHB)

  15. Network Science Research Laboratory (NSRL) Telemetry Warehouse

    Science.gov (United States)

    2016-06-01

    Collection, Storage, and Retrieval 3 3.2 Comparative Analysis 4 3.3 Data Processing 4 4. Architecture 4 4.1 NTW Database 6 4.2 NTW Server 6 4.4...efforts between ARL and the US Naval Research Laboratory (NRL). The primary emulation tools used by ARL are the Extendable Mobile Ad -Hoc Network...procedure call (gRPC) system. The gRPC system uses the Google protocol buffers compiler to generate the code for the server . gRPC handles many of the basic

  16. The Automated Primate Research Laboratory (APRL)

    Science.gov (United States)

    Pace, N.; Smith, G. D.

    1972-01-01

    A description is given of a self-contained automated primate research laboratory to study the effects of weightlessness on subhuman primates. Physiological parameters such as hemodynamics, respiration, blood constituents, waste, and diet and nutrition are analyzed for abnormalities in the simulated space environment. The Southeast Asian pig-tailed monkey (Macaca nemistrina) was selected for the experiments owing to its relative intelligence and learning capacity. The objective of the program is to demonstrate the feasibility of a man-tended primate space flight experiment.

  17. National Renewable Energy Laboratory 2005 Research Review

    Energy Technology Data Exchange (ETDEWEB)

    Brown, H.; Gwinner, D.; Miller, M.; Pitchford, P.

    2006-06-01

    Science and technology are at the heart of everything we do at the National Renewable Energy Laboratory, as we pursue innovative, robust, and sustainable ways to produce energy--and as we seek to understand and illuminate the physics, chemistry, biology, and engineering behind alternative energy technologies. This year's Research Review highlights the Lab's work in the areas of alternatives fuels and vehicles, high-performing commercial buildings, and high-efficiency inverted, semi-mismatched solar cells.

  18. Definition of experiments and instruments for a communication/navigation research laboratory. Volume 3: Laboratory descriptions

    Science.gov (United States)

    1972-01-01

    The following study objectives are covered: (1) identification of major laboratory equipment; (2) systems and operations analysis in support of the laboratory design; and (3) conceptual design of the comm/nav research laboratory.

  19. NECESSITY FOR UNDERGROUND RESEARCH LABORATORY IN CROATIA

    Directory of Open Access Journals (Sweden)

    Želimir Vejnović

    2012-07-01

    Full Text Available Nuclear power plant (NPP Krško has a license to operate until 2023, and under the current agreement between the Republic of Slovenia and the Republic of Croatia, countries are bound to dispose one half of radioactive waste produced during the operation time and after decommissioning of NPP each. Safe long-term management of high level radioactive waste and spent fuel represents one of the most important issues of the modern world. The best way to provide practical demonstration of repository’s safety, which will be one of convincing arguments in the process of licensing future repository, is developed underground research laboratory (URL. Existence of URL open to international co-operation would certainly improve the international recognition and credibility of Croatian programme, as well as allow dissemination of scientific research results to a broader scientific community (the paper is published in Croatian.

  20. Bringing ayahuasca to the clinical research laboratory.

    Science.gov (United States)

    Riba, Jordi; Barbanoj, Manel J

    2005-06-01

    Since the winter of 1999, the authors and their research team have been conducting clinical studies involving the administration of ayahuasca to healthy volunteers. The rationale for conducting this kind of research is twofold. First, the growing interest of many individuals for traditional indigenous practices involving the ingestion of natural psychotropic drugs such as ayahuasca demands the systematic study of their pharmacological profiles in the target species, i.e., human beings. The complex nature of ayahuasca brews combining a large number of pharmacologically active compounds requires that research be carried out to establish the safety and overall pharmacological profile of these products. Second, the authors believe that the study of psychedelics in general calls for renewed attention. Although the molecular and electrophysiological level effects of these drugs are relatively well characterized, current knowledge of the mechanisms by which these compounds modify the higher order cognitive processes in the way they do is still incomplete, to say the least. The present article describes the development of the research effort carried out at the Autonomous University of Barcelona, commenting on several methodological aspects and reviewing the basic clinical findings. It also describes the research currently underway in our laboratory, and briefly comments on two new studies we plan to undertake in order to further our knowledge of the pharmacology of ayahuasca.

  1. EPA Region 6 Laboratory Method Specific Analytical Capabilities with Sample Concentration Range

    Science.gov (United States)

    EPA Region 6 Environmental Services Branch (ESB) Laboratory is capable of analyzing a wide range of samples with concentrations ranging for low part-per trillion (ppt) to low percent () levels, depending on the sample matrix.

  2. DESALINATION AND WATER TREATMENT RESEARCH AT SANDIA NATIONAL LABORATORIES.

    Energy Technology Data Exchange (ETDEWEB)

    Rigali, Mark J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Miller, James E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Altman, Susan J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Biedermann, Laura [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Brady, Patrick Vane. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kuzio, Stephanie P. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Nenoff, Tina M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Rempe, Susan [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-11-01

    Water is the backbone of our economy - safe and adequate supplies of water are vital for agriculture, industry, recreation, and human consumption. While our supply of water today is largely safe and adequate, we as a nation face increasing water supply challenges in the form of extended droughts, demand growth due to population increase, more stringent health-based regulation, and competing demands from a variety of users. To meet these challenges in the coming decades, water treatment technologies, including desalination, will contribute substantially to ensuring a safe, sustainable, affordable, and adequate water supply for the United States. This overview documents Sandia National Laboratories' (SNL, or Sandia) Water Treatment Program which focused on the development and demonstration of advanced water purification technologies as part of the larger Sandia Water Initiative. Projects under the Water Treatment Program include: (1) the development of desalination research roadmaps (2) our efforts to accelerate the commercialization of new desalination and water treatment technologies (known as the 'Jump-Start Program),' (3) long range (high risk, early stage) desalination research (known as the 'Long Range Research Program'), (4) treatment research projects under the Joint Water Reuse & Desalination Task Force, (5) the Arsenic Water Technology Partnership Program, (6) water treatment projects funded under the New Mexico Small Business Administration, (7) water treatment projects for the National Energy Technology Laboratory (NETL) and the National Renewable Energy Laboratory (NREL), (8) Sandia- developed contaminant-selective treatment technologies, and finally (9) current Laboratory Directed Research and Development (LDRD) funded desalination projects.

  3. Tritium Research Laboratory safety analysis report

    Energy Technology Data Exchange (ETDEWEB)

    Wright, D.A.

    1979-03-01

    Design and operational philosophy has been evolved to keep radiation exposures to personnel and radiation releases to the environment as low as reasonably achievable. Each experiment will be doubly contained in a glove box and will be limited to 10 grams of tritium gas. Specially designed solid-hydride storage beds may be used to store temporarily up to 25 grams of tritium in the form of tritides. To evaluate possible risks to the public or the environment, a review of the Sandia Laboratories Livermore (SLL) site was carried out. Considered were location, population, land use, meteorology, hydrology, geology, and seismology. The risks and the extent of damage to the TRL and vital systems were evaluated for flooding, lightning, severe winds, earthquakes, explosions, and fires. All of the natural phenomena and human error accidents were considered credible, although the extent of potential damage varied. However, rather than address the myriad of specific individual consequences of each accident scenario, a worst-case tritium release caused indirectly by an unspecified natural phenomenon or human error was evaluated. The maximum credible radiological accident is postulated to result from the release of the maximum quantity of gas from one experiment. Thus 10 grams of tritium gas was used in the analysis to conservatively estimate the maximum whole-body dose of 1 rem at the site boundary and a maximum population dose of 600 man-rem. Accidental release of this amount of tritium implies simultaneous failure of two doubly contained systems, an occurrence considered not credible. Nuclear criticality is impossible in this facility. Based upon the analyses performed for this report, we conclude that the Tritium Research Laboratory can be operated without undue risk to employees, the general public, or the environment. (ERB)

  4. Research programs at the Department of Energy National Laboratories. Volume 2: Laboratory matrix

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-01

    For nearly fifty years, the US national laboratories, under the direction of the Department of Energy, have maintained a tradition of outstanding scientific research and innovative technological development. With the end of the Cold War, their roles have undergone profound changes. Although many of their original priorities remain--stewardship of the nation`s nuclear stockpile, for example--pressing budget constraints and new federal mandates have altered their focus. Promotion of energy efficiency, environmental restoration, human health, and technology partnerships with the goal of enhancing US economic and technological competitiveness are key new priorities. The multiprogram national laboratories offer unparalleled expertise in meeting the challenge of changing priorities. This volume aims to demonstrate each laboratory`s uniqueness in applying this expertise. It describes the laboratories` activities in eleven broad areas of research that most or all share in common. Each section of this volume is devoted to a single laboratory. Those included are: Argonne National Laboratory; Brookhaven National Laboratory; Idaho National Engineering Laboratory; Lawrence Berkeley Laboratory; Lawrence Livermore National Laboratory; Los Alamos National Laboratory; National Renewable Energy Laboratory; Oak Ridge National Laboratory; Pacific Northwest Laboratory; and Sandia National Laboratories. The information in this volume was provided by the multiprogram national laboratories and compiled at Lawrence Berkeley Laboratory.

  5. Frontiers for Laboratory Research of Magnetic Reconnection

    Energy Technology Data Exchange (ETDEWEB)

    Ji, Hantao [Princeton University; Guo, Fan [Los Alamos National Laboratory

    2015-07-16

    Magnetic reconnection occcurs throughout heliophysical and astrophysical plasmas as well as in laboratory fusion plasmas. Two broad categories of reconnection models exist: collisional MHD and collisionless kinetic. Eight major questions with respect to magnetic connection are set down, and past and future devices for studying them in the laboratory are described. Results of some computerized simulations are compared with experiments.

  6. Physical Sciences Laboratory (PSL)

    Data.gov (United States)

    Federal Laboratory Consortium — PNNL's Physical Sciences Laboratory (PSL) houses 22 research laboratories for conducting a wide-range of research including catalyst formulation, chemical analysis,...

  7. CNR LARA project, Italy: Airborne laboratory for environmental research

    Science.gov (United States)

    Bianchi, R.; Cavalli, R. M.; Fiumi, L.; Marino, C. M.; Pignatti, S.

    1995-01-01

    The increasing interest for the environmental problems and the study of the impact on the environment due to antropic activity produced an enhancement of remote sensing applications. The Italian National Research Council (CNR) established a new laboratory for airborne hyperspectral imaging, the LARA Project (Laboratorio Aero per Ricerche Ambientali - Airborne Laboratory for Environmental Research), equipping its airborne laboratory, a CASA-212, mainly with the Daedalus AA5000 MIVIS (Multispectral Infrared and Visible Imaging Spectrometer) instrument. MIVIS's channels, spectral bandwidths, and locations are chosen to meet the needs of scientific research for advanced applications of remote sensing data. MIVIS can make significant contributions to solving problems in many diverse areas such as geologic exploration, land use studies, mineralogy, agricultural crop studies, energy loss analysis, pollution assessment, volcanology, forest fire management and others. The broad spectral range and the many discrete narrow channels of MIVIS provide a fine quantization of spectral information that permits accurate definition of absorption features from a variety of materials, allowing the extraction of chemical and physical information of our environment. The availability of such a hyperspectral imager, that will operate mainly in the Mediterranean area, at the present represents a unique opportunity for those who are involved in environmental studies and land-management to collect systematically large-scale and high spectral-spatial resolution data of this part of the world. Nevertheless, MIVIS deployments will touch other parts of the world, where a major interest from the international scientific community is present.

  8. Development of photoacoustic sensing platforms at the Army Research Laboratory.

    Science.gov (United States)

    Holthoff, Ellen L; Pellegrino, Paul M

    2017-01-20

    Traditionally, chemical sensing platforms have been hampered by the opposing concerns of increasing sensor capability while maintaining a minimal package size. Current sensors, although reasonably sized, are geared to more classical chemical threats, and the ability to expand their capabilities to a broader range of emerging threats is uncertain. Recently, photoacoustic spectroscopy, employed in a sensor format, has shown enormous potential to address these ever-changing threats. Photoacoustic spectroscopy is one of the more flexible infrared spectroscopy variants, and that flexibility allows for the construction of sensors that are designed for specific tasks. The Army Research Laboratory has, for the past 14 years, engaged in research into the development of photoacoustic sensing platforms with the goal of sensor miniaturization and the detection of a variety of chemical targets both proximally and at range. This paper reviews this work.

  9. Laboratory Directed Research and Development FY 2000 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Al-Ayat, R

    2001-05-24

    This Annual Report provides an overview of the FY2000 Laboratory Directed Research and Development (LDRD) Program at Lawrence Livermore National Laboratory (LLNL) and presents a summary of the results achieved by each project during the year.

  10. 75 FR 57833 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2010-09-22

    ... AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development... Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit..., 2010......... Crowne Plaza Neurobiology-D November 19, 2010......... Crowne Plaza Pulmonary Medicine...

  11. 77 FR 64598 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2012-10-22

    ... AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development... Biomedical Laboratory Research and Development and Clinical Science Research and Development Services..., 2012...... *VA Central Office. Cellular and Molecular Medicine...... November 19, 2012...... Sheraton...

  12. Experimental forests, ranges, and watersheds in the Northern Rocky Mountains: A compendium of outdoor laboratories in Utah, Idaho, and Montana

    Science.gov (United States)

    Wyman C. Schmidt; Judy L. Friede

    1996-01-01

    This is a compendium of experimental forests, ranges, watersheds, and other outdoor laboratories, formally established by the Forest Service and Agricultural Research Service of the U.S. Department of Agriculture, and the universities in Utah, Idaho, and Montana. The purposes, histories, natural resource bases, data bases, past and current studies, locations, and who...

  13. Power and energy research at the Army Research Laboratory

    Science.gov (United States)

    Shaffer, Edward C.; Wood, Mark C.

    2012-06-01

    The requirement for power and energy in a modernized, highly digital and network-centric Army is growing exponentially. In addition to the ongoing demand for improved soldier portable power sources, the need for more electric capabilities for combat and unmanned platforms and the requirements of emerging Operational Energy doctrine are driving development of high density, energy efficient power technologies. The Army Research Laboratory (ARL) is addressing these needs through developing a number of underpinning power and energy component technologies at the fundamental research level. ARL is leveraging core expertise in microelectronics and micro-electro-mechanical systems (MEMS), energy conversion, energy storage, and wideband gap materials and devices to advance selected niche areas that address military demands beyond commercial needs in partnership with the Army Research, Development and Engineering centers (RDECs), other services, other agencies, industry, and academia. The technologies under development can be broadly characterized under power generation and energy conversion, energy storage, power distribution, and thermal management. This discussion outlines progress, approach and the way ahead for ARL efforts.

  14. Spectral range calculation inside the Research Irradiating Facility Army Technology Center using code MCNPX and comparison with the spectra of energy Caesium 137 raised in laboratory; Calculo gama espectral no interior do irradiador de pesquisa do Centro Tecnologico do Exercito utilizando o codigo MCNPX e comparacao com espectros de energia do Cesio 137 levantados em laboratorio

    Energy Technology Data Exchange (ETDEWEB)

    Gomes, Renato G.; Rebello, Wilson F.; Cavaliere, Marcos Paulo; Vellozo, Sergio O.; Moreira Junior, Luis, E-mail: renatoguedes@ime.eb.br, E-mail: rebello@ime.eb.br, E-mail: eng.cavaliere@gmail.com, E-mail: vellozo@cbpf.br, E-mail: luisjrmoreira@hotmail.com [Instituto Militar de Engenharia (IME), Rio de Janeiro, RJ (Brazil); Vital, Helio C., E-mail: vital@ctex.eb.br [Centro Tecnologico do Exercito (CTEX), Barra de Guaratiba, RJ (Brazil); Silva, Ademir X., E-mail: ademir@con.ufrj.br [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ (Brazil)

    2013-07-01

    Using the MCNPX code, the objective was to calculate by means of computer simulation spectroscopy range inside the irradiation chamber upper radiator gamma research irradiating facility Army Technology Center (CTEx). The calculations were performed in the spectral range usual 2 points for research purposes irradiating the energy spectra of gamma rays from the source of Cesium chloride 137. Sought the discretization of the spectrum in 100 channels at points of upper bound of 1cm higher and lower dose rates previously known. It was also conducted in the laboratory lifting the spectrum of Cesium-137 source using NaI scintillator detector and multichannel analyzer. With the source spectrum Cesium-137 contained in the literature and raised in the laboratory, both used as reference for comparison and analysis in terms of probability of emission maximum of 0.661 MeV The spectra were quite consistent in terms of the behavior of the energy distributions with scores. The position of maximum dose rate showed absorption detection almost maximum energy of 0.661 MeV photopeak In the spectrum of the position of minimum dosage rate, it was found that due to the removal of the source point of interest, some loss detection were caused by Compton scattering. (author)

  15. Range management research, Fort Valley Experimental Forest (P-53)

    Science.gov (United States)

    Henry A. Pearson; Warren P. Clary; Margaret M. Moore; Carolyn Hull Sieg

    2008-01-01

    Range management research at the Fort Valley Experimental Forest during the past 100 years has provided scientific knowledge for managing ponderosa pine forests and forest-range grazing lands in the Southwest. Three research timeperiods are identified: 1908 to 1950, 1950 to 1978, and 1978 to 2008. Early research (1908-1950) addressed ecological effects of livestock...

  16. Design of a preprototype Stirling Laboratory Research Engine

    Science.gov (United States)

    Hoehn, F. W.; Mcdougal, A. R.

    1978-01-01

    A description is given for the design and fabrication of a first generation, preprototype Stirling Laboratory Research Engine. The engine represents the first step in providing a research tool to be used to support the development of a broad range of analytical modeling and experimental efforts, and to evaluate new approaches to the design of components for Stirling engines. The test engine is a horizontally-opposed, two-piston, single-acting machine with a dual crankshaft drive mechanism. The preprototype engine is rated at 10 kW and was designed for maximum modularity. The long term objective of the project is to provide a proven design of a standardized test engine, which can be commercially produced, for national research on Stirling cycle machines.

  17. Air Force Research Laboratory Technology Milestones 2007

    Science.gov (United States)

    2007-01-01

    constituent parts (a lower grid section and a top skin) fasten in place with snap -fit technology, meaning that they snap together without the need for drilled... Neutron Source at Argonne National Laboratory-to obtain neutron diffraction measurements. Increases in aeroengine operating temperatures exceed the limits

  18. Ultra-Short-Pulse Laser Effects Research and Analysis Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Enables research into advanced laser countermeasure techniques.DESCRIPTION: This laser facility has a capability to produce very high peak power levels of...

  19. Sandia, California Tritium Research Laboratory transition and reutilization project

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, T.B. [Sandia National Lab., Albuquerque, NM (United States)

    1997-02-01

    This paper describes a project within Sandia National Laboratory to convert the shut down Tritium Research Laboratory into a facility which could be reused within the laboratory complex. In the process of decommissioning and decontaminating the facility, the laboratory was able to save substantial financial resources by transferring much existing equipment to other DOE facilities, and then expeditiously implementing a decontamination program which has resulted in the building being converted into laboratory space for new lab programs. This project of facility reuse has been a significant financial benefit to the laboratory.

  20. Naval Research Laboratory Fact Book 2012

    Science.gov (United States)

    2012-11-01

    EMC testing chamber Facilities: Spacecraft high-reliability electronic and electrical rework facility Spacecraft electronic systems integration...1,000 hours in the A-6 Intruder and flew missions in support of Operation Desert Shield . In 1993, he was selected for U.S. Naval Test Pilot School and...require this space. There are 12 of these laboratories within the building. They provide shielding from electromagnetic interference, and very low floor

  1. Laboratory and cyclotron requirements for PET research

    Energy Technology Data Exchange (ETDEWEB)

    Schlyer, D.J.

    1993-06-01

    This report describes four types of PET facilities: Clinical PET with no radionuclide production; clinical PET with a small accelerator; clinical PET with research support; and research PET facilities. General facility considerations are also discussed.

  2. Report on the Acadiana Research Laboratory nuclear microprobe system

    Science.gov (United States)

    Glass, Gary A.; Hollerman, William A.; Hynes, Shelly F.; Fournet, Justin; Bailey, Alan M.; Liao, Changgeng

    2001-07-01

    The Acadiana Research Laboratory of the University of Louisiana at Lafayette provides high energy ion beams for materials research. Major components of the ion beam systems include a National Electrostatics Corporation (NEC) 1.7 MV tandem Pelletron accelerator system with both SNICS and RF ion sources and a Varian CF-4 200 kV implanter. The NEC Pelletron has three operational beamlines that provide a wide range of capabilities for materials modification and analysis, including such techniques as PIXE, PIGE, RBS, RFS, TOF-ERDA and ion implantation. An Oxford Microbeams Ltd. microprobe system was recently declared operational with the attainment of a 1.5 μm×2.0 μm beam spot size. Microprobe techniques presently available include μPIXE, μRBS and scanning transmission ion microscopy (STIM).

  3. Laboratory Directed Research and Development FY-15 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Pillai, Rekha Sukamar [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-03-01

    The Laboratory Directed Research and Development (LDRD) Program at Idaho National Laboratory (INL) reports its status to the U.S. Department of Energy (DOE) by March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the laboratory director broad flexibility for program implementation. LDRD funds are obtained through a charge to all INL programs. This report includes summaries of all INL LDRD research activities supported during Fiscal Year (FY) 2015.

  4. Laboratory stands for research of security systems’ components

    Directory of Open Access Journals (Sweden)

    Joanna Ćwirko

    2015-12-01

    Full Text Available The article presents two laboratory stands for research of basic security systems’ components. PIR detectors are the most widely used components in alarm systems. PIR detector element is a pyroelectric detector — its parameters determine the sensitivity of the detector and its resistance to “false alarms”. The completed laboratory stand allows for a comprehensive study of pyroelectric detectors, including work in a wide temperature range — to protect peripheral objects. The stand consists of radiation source (calibrator, the mechanical modulator, Peltier (change of temperature detector and measuring instruments.The main purpose of access control system (ACC is the selection of access to a wide variety of objects and technical systems. Realized laboratory set consists of 4 individual stands KD. Single stand KD is controlled by the transition controller module and base element is the door module. Depending on the desired configuration of the door module is equipped with: a smart card reader with keypad, Dallas chip reader, opening button or keypad. The access is defined for users — we have a weekly schedule, day and so-called time frames.[b]Keywords[/b]: pyroelectric detector, environment studies, access control system

  5. Laboratory Directed Research and Development FY-10 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Dena Tomchak

    2011-03-01

    The FY 2010 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support the future DOE missions and national research priorities. LDRD is essential to the INL -- it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enhances technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development.

  6. Reservoir sedimentation research at the National Sedimentation Laboratory

    Science.gov (United States)

    Researchers at the National Sedimentation Laboratory have made important contributions to reservoir sedimentation research for most of the 50 years that the laboratory has existed. Early publications from the mid 1960s to the mid 1970s reported work on the development of gamma ray sediment measurem...

  7. Laboratory Directed Research and Development annual report, fiscal year 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The Department of Energy Order 413.2(a) establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 413.2, LDRD is research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this Order. DOE Order 413.2 requires that each laboratory submit an annual report on its LDRD activities to the cognizant Secretarial Officer through the appropriate Operations Office Manager. The report provided in this document represents Pacific Northwest National Laboratory`s LDRD report for FY 1997.

  8. Interlaboratory comparison in the pressure range from 0 to 2 MPa for accredited calibration laboratories

    Directory of Open Access Journals (Sweden)

    Bermanec Lovorka Grgec

    2015-01-01

    Full Text Available This paper describes procedure and results of the interlaboratory comparison that was organised by Croatian national pressure laboratory (HMI/FSB-LPM between eight accredited pressure calibration laboratories. Comparison was performed in the gauge pressure range from 0 to 2 MPa with pressure transducer as transfer standard and using gas as transmitting medium. Basic aim of this comparison was to improve measurement methods and the measurement uncertainties of each participating laboratory. Analysis of the measurement results are given by calculating the deviation, En, normalized with respect to the stated measurement uncertainties.

  9. Clinical disease and laboratory abnormalities in free-ranging desert tortoises in California (1990-1995)

    Science.gov (United States)

    Christopher, Mary M.; Berry, Kristin H.; Henen, Brian T.; Nagy, Kenneth A.

    2003-01-01

    Desert tortoise (Gopherus agassizii) populations have experienced precipitous declines resulting from the cumulative impact of habitat loss and human and disease-related mortality. Diagnosis of disease in live, free-ranging tortoises is facilitated by evaluation of clinical signs and laboratory test results but may be complicated by seasonal and environmental effects. The goals of this study were: 1) to describe and monitor clinical and laboratory signs of disease in adult, free-ranging desert tortoises at three sites in the Mojave Desert of California (USA) between October 1990 and October 1995; 2) to evaluate associations between clinical signs and hematologic, biochemical, serologic, and microbiologic test results; 3) to characterize disease patterns by site, season, and sex; and 4) to assess the utility of diagnostic tests in predicting morbidity and mortality. Venous blood samples were obtained four times per year from tortoises of both sexes at the Desert Tortoise Research Natural Area (DTNA), Goffs/Fenner Valley, and Ivanpah Valley. Tortoises were given a physical examination, and clinical abnormalities were graded by type and severity. Of 108 tortoises, 68.5% had clinical signs of upper respiratory tract disease consistent with mycoplasmosis at least once during the study period. In addition, 48.1% developed moderate to severe shell lesions consistent with cutaneous dyskeratosis. Ulcerated or plaque-like oral lesions were noted on single occasions in 23% of tortoises at Goffs and 6% of tortoises at Ivanpah. Tortoises with oral lesions were significantly more likely than tortoises without lesions to have positive nasal cultures for Mycoplasma agassizii(P=0.001) and to be dehydrated (P=0.0007). Nine tortoises had marked azotemia (blood urea nitrogen [BUN] >100 mg/dl) or persistent azotemia (BUN 63–76 mg/dl); four of these died, three of which had necropsy confirmation of urinary tract disease. Laboratory tests had low sensitivity but high specificity in

  10. Army Research Laboratory 2009 Annual Review

    Science.gov (United States)

    2009-01-01

    Science and Humanities Symposium MWM – Materials World Modules REAP – Research and Engineering Apprentice Program SEAP – Science and Engineering ...Development, and Engineering Center’s (CERDEC’s) Mobile Ad Hoc Network (MANET) Design program. • The Distributed Survivable Resource Control-tactical...the individual Soldier. To cite just one such advance, researchers at MIT have created a genetically engineered , super-light-weight, high- power

  11. Laboratory Directed Research and Development Program: FY 2015 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    SLAC,

    2016-04-04

    The Department of Energy (DOE) and the SLAC National Accelerator Laboratory (SLAC) encourage innovation, creativity, originality and quality to maintain the Laboratory’s research activities and staff at the forefront of science and technology. To further advance its scientific research capabilities, the Laboratory allocates a portion of its funds for the Laboratory Directed Research and Development (LDRD) program. With DOE guidance, the LDRD program enables SLAC scientists to make rapid and significant contributions that seed new strategies for solving important national science and technology problems. The LDRD program is conducted using existing research facilities.

  12. Laboratory Directed Research and Development FY2001 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Al-Ayat, R

    2002-06-20

    Established by Congress in 1991, the Laboratory Directed Research and Development (LDRD) Program provides the Department of Energy (DOE)/National Nuclear Security Administration (NNSA) laboratories, like Lawrence Livermore National Laboratory (LLNL or the Laboratory), with the flexibility to invest up to 6% of their budget in long-term, high-risk, and potentially high payoff research and development (R&D) activities to support the DOE/NNSA's national security missions. By funding innovative R&D, the LDRD Program at LLNL develops and extends the Laboratory's intellectual foundations and maintains its vitality as a premier research institution. As proof of the Program's success, many of the research thrusts that started many years ago under LDRD sponsorship are at the core of today's programs. The LDRD Program, which serves as a proving ground for innovative ideas, is the Laboratory's most important single resource for fostering excellent science and technology for today's needs and tomorrow's challenges. Basic and applied research activities funded by LDRD enhance the Laboratory's core strengths, driving its technical vitality to create new capabilities that enable LLNL to meet DOE/NNSA's national security missions. The Program also plays a key role in building a world-class multidisciplinary workforce by engaging the Laboratory's best researchers, recruiting its future scientists and engineers, and promoting collaborations with all sectors of the larger scientific community.

  13. Close-range imaging and research priorities in Europe

    Directory of Open Access Journals (Sweden)

    P. Patias

    2014-06-01

    Full Text Available Since 1984, the European Union’s Framework Program for Research and Innovation has been the main instrument for funding research. Specific priorities, objectives and types of funded activities vary between funding periods. Horizon 2020 is the biggest EU Research and Innovation programme ever with nearly € 80 billion of funding available over 7 years (2014–2020. H2020 is based on three pillars: (i Excellent science, (ii Industrial leadership, (iii Societal challenges. The current economic crisis in Europe and elsewhere leads to extended shortage of research budgets in national levels, which in turn leads researchers to search funds in the highly competitive transnational research instruments, as H2020. This paper : - draws the overall picture of Horizon 2020 - investigates the position of close-range imaging technologies, applications and research areas - presents the research challenges in H2020 that offer funding opportunities in close-range imaging

  14. Laboratory Directed Research and Development Annual Report FY 2016

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, Kelly O. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2017-03-30

    A national laboratory must establish and maintain an environment in which creativity and innovation are encouraged and supported in order to fulfill its missions and remain viable in the long term. As such, multiprogram laboratories are given discretion to allocate a percentage of their operating budgets to support research and development projects that align to PNNL’s and DOE’s missions and support the missions of other federal agencies, including DHS, DOD, and others. DOE Order 413.2C sets forth DOE’s Laboratory Directed Research and Development (LDRD) policy and guidelines for DOE multiprogram laboratories, and it authorizes the national laboratories to allocate up to 6 percent of their operating budgets to fund the program. LDRD is innovative research and development, selected by the Laboratory Director or his/her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory. The projects supported by LDRD funding all have demonstrable ties to DOE/DHS missions and may also be relevant to the missions of other federal agencies that sponsor work at the Laboratory. The program plays a key role in attracting the best and brightest scientific staff, which is needed to serve the highest priority DOE mission objectives. Individual project reports comprise the bulk of this LDRD report. The Laboratory focuses its LDRD research on scientific assets that often address more than one scientific discipline.

  15. Laboratory Directed Research and Development Program FY 2008 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    editor, Todd C Hansen

    2009-02-23

    consideration and review by the Office of Science Program Offices, such as LDRD projects germane to new research facility concepts and new fundamental science directions. Berkeley Lab LDRD program also play an important role in leveraging DOE capabilities for national needs. The fundamental scientific research and development conducted in the program advances the skills and technologies of importance to our Work For Others (WFO) sponsors. Among many directions, these include a broad range of health-related science and technology of interest to the National Institutes of Health, breast cancer and accelerator research supported by the Department of Defense, detector technologies that should be useful to the Department of Homeland Security, and particle detection that will be valuable to the Environmental Protection Agency. The Berkeley Lab Laboratory Directed Research and Development Program FY2008 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the supported projects and summarizes their accomplishments. It constitutes a part of the LDRD program planning and documentation process that includes an annual planning cycle, project selection, implementation, and review.

  16. Research Review: Laboratory Student Magazine Programs.

    Science.gov (United States)

    Wheeler, Tom

    1994-01-01

    Explores research on student-produced magazines at journalism schools, including the nature of various programs and curricular structures, ethical considerations, and the role of faculty advisors. Addresses collateral sources that provide practical and philosophical foundations for the establishment and conduct of magazine production programs.…

  17. Air Force Cambridge Research Laboratories balloon operations

    Science.gov (United States)

    Danaher, T. J.

    1974-01-01

    The establishment and functions of the AFCRL balloon operations facility are discussed. The types of research work conducted by the facility are defined. The facilities which support the balloon programs are described. The free balloon and tethered balloon capabilities are analyzed.

  18. Naval Arctic Research Laboratory (NARL) Subsurface Containment Berm Investigation

    Science.gov (United States)

    2015-10-01

    the survey transects explored. 15. SUBJECT TERMS Barrow Alaska Containment berm Geophysical methods Ground-penetrating radar Permafrost ...Research and Engineering Laboratory (CRREL) Alaska Research Office Building 4070, 9th Street Fort Wainwright, AK 99703 Final Report Approved for...The former Navy Arctic Research Laboratory Airstrip Site in Barrow, Alaska , has a history of fuel spills. Various methods have been used to re- mediate

  19. NASA/WVU Software Research Laboratory, 1995

    Science.gov (United States)

    Sabolish, George J.; Callahan, John R.

    1995-01-01

    In our second year, the NASA/WVU Software Research Lab has made significant strides toward analysis and solution of major software problems related to V&V activities. We have established working relationships with many ongoing efforts within NASA and continue to provide valuable input into policy and decision-making processes. Through our publications, technical reports, lecture series, newsletters, and resources on the World-Wide-Web, we provide information to many NASA and external parties daily. This report is a summary and overview of some of our activities for the past year. This report is divided into 6 chapters: Introduction, People, Support Activities, Process, Metrics, and Testing. The Introduction chapter (this chapter) gives an overview of our project beginnings and targets. The People chapter focuses on new people who have joined the Lab this year. The Support chapter briefly lists activities like our WWW pages, Technical Report Series, Technical Lecture Series, and Research Quarterly newsletter. Finally, the remaining four chapters discuss the major research areas that we have made significant progress towards producing meaningful task reports. These chapters can be regarded as portions of drafts of our task reports.

  20. Gestational age-specific reference ranges from different laboratories misclassify pregnant women's thyroid status

    DEFF Research Database (Denmark)

    Bliddal, Sofie; Feldt-Rasmussen, Ulla; Boas, Malene

    2014-01-01

    OBJECTIVES: Correct interpretation of thyroid status during pregnancy is vital to secure fetal development. Pregnancy-related changes in maternal thyroid status necessitate the use of gestational age-specific reference ranges. In this study, we investigated between-laboratory reproducibility of t...

  1. Laboratory Directed Research and Development Program FY 2006 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Sjoreen, Terrence P [ORNL

    2007-04-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the US Departmental of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2006. The associated FY 2006 ORNL LDRD Self-Assessment (ORNL/PPA-2007/2) provides financial data about the FY 2006 projects and an internal evaluation of the program's management process.

  2. Laboratory directed research and development program, FY 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-01

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory`s forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances the Laboratory`s core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. Areas eligible for support include: (1) Work in forefront areas of science and technology that enrich Laboratory research and development capability; (2) Advanced study of new hypotheses, new experiments, and innovative approaches to develop new concepts or knowledge; (3) Experiments directed toward proof of principle for initial hypothesis testing or verification; and (4) Conception and preliminary technical analysis to explore possible instrumentation, experimental facilities, or new devices.

  3. Laboratory Directed Research and Development Program Assessment for FY 2014

    Energy Technology Data Exchange (ETDEWEB)

    Hatton, D. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2014-03-01

    Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2B dated April 19, 2006. This report fulfills that requirement.

  4. 76 FR 79273 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2011-12-21

    ... AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development... Eligibility of the Joint Biomedical Laboratory Research and Development and Clinical Science Research and... biomedical, behavioral, and clinical science research. The panel meeting will be open to the public for...

  5. Laboratory directed research and development program FY 2003

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd

    2004-03-27

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. In FY03, Berkeley Lab was authorized by DOE to establish a funding ceiling for the LDRD program of $15.0 M, which equates to about 3.2% of Berkeley Lab's FY03 projected operating and capital equipment budgets. This funding level was provided to develop new scientific ideas and opportunities and allow the Berkeley Lab Director an opportunity to initiate new directions. Budget constraints limited available resources, however, so only $10.1 M was expended for operating and $0.6 M for capital equipment (2.4% of actual Berkeley Lab FY03 costs). In FY03, scientists submitted 168 proposals, requesting over $24.2 M in operating funding. Eighty-two projects were funded, with awards ranging from $45 K to $500 K. These projects are summarized in Table 1.

  6. Long-term avian research at the San Joaquin Experimental Range: recommendations for monitoring and managing oak woodlands

    Science.gov (United States)

    Kathryn L. Purcell

    2011-01-01

    Experimental forests and ranges are living laboratories that provide opportunities for conducting scientific research and transferring research results to partners and stakeholders. They are invaluable for their long-term data and capacity to foster collaborative, interdisciplinary research. The San Joaquin Experimental Range (SJER) was established to develop...

  7. Laboratory directed research and development 2006 annual report.

    Energy Technology Data Exchange (ETDEWEB)

    Westrich, Henry Roger

    2007-03-01

    This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 2006. In addition to a programmatic and financial overview, the report includes progress reports from 430 individual R&D projects in 17 categories.

  8. Earth System Research Laboratory Long-Term Surface Aerosol Measurements

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Aerosol measurements began at the NOAA Earth System Research Laboratory (ESRL) Global Monitoring Division (GMD) baseline observatories in the mid-1970's with the...

  9. Argonne National Laboratory research offers clues to Alzheimer's plaques

    CERN Multimedia

    2003-01-01

    Researchers from Argonne National Laboratory and the University of Chicago have developed methods to directly observe the structure and growth of microscopic filaments that form the characteristic plaques found in the brains of those with Alzheimer's Disease (1 page).

  10. Research and Laboratory Instruction--An Experiment in Teaching

    Science.gov (United States)

    Kramm, Kenneth R.

    1976-01-01

    Describes an attempt to incorporate research into laboratory work in an introductory ecology class and a senior seminar. The investigation involves the examination of rhythms of food consumption and circadian activities in humans. (GS)

  11. Laboratory Directed Research and Development Program

    Energy Technology Data Exchange (ETDEWEB)

    Ogeka, G.J.; Romano, A.J.

    1992-12-01

    This report briefly discusses the following research: Advances in Geoexploration; Transvenous Coronary Angiography with Synchrotron X-Rays; Borehole Measurements of Global Warming; Molecular Ecology: Development of Field Methods for Microbial Growth Rate and Activity Measurements; A New Malaria Enzyme - A Potential Source for a New Diagnostic Test for Malaria and a Target for a New Antimalarial Drug; Basic Studies on Thoron and Thoron Precursors; Cloning of the cDNA for a Human Serine/Threonine Protein Kinase that is Activated Specifically by Double-Stranded DNA; Development of an Ultra-Fast Laser System for Accelerator Applications; Cluster Impact Fusion; Effect of a Bacterial Spore Protein on Mutagenesis; Structure and Function of Adenovirus Penton Base Protein; High Resolution Fast X-Ray Detector; Coherent Synchrotron Radiation Longitudinal Bunch Shape Monitor; High Grain Harmonic Generation Experiment; BNL Maglev Studies; Structural Investigations of Pt-Based Catalysts; Studies on the Cellular Toxicity of Cocaine and Cocaethylene; Human Melanocyte Transformation; Exploratory Applications of X-Ray Microscopy; Determination of the Higher Ordered Structure of Eukaryotic Chromosomes; Uranium Neutron Capture Therapy; Tunneling Microscopy Studies of Nanoscale Structures; Nuclear Techiques for Study of Biological Channels; RF Sources for Accelerator Physics; Induction and Repair of Double-Strand Breaks in the DNA of Human Lymphocytes; and An EBIS Source of High Charge State Ions up to Uranium.

  12. Coral Research Data from NOAA's Undersea Research Center, Hawaii Undersea Research Laboratory, NOAA's Undersea Research Program (NURP)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA's Undersea Research Center, the Hawaii Undersea Research Laboratory, explores and studies the waters around the Main Hawaiian Islands, Northwest Hawaiian...

  13. Identifying and Addressing Challenges to Research in University Laboratory Preschools

    Science.gov (United States)

    File, Nancy

    2012-01-01

    Research Findings: This essay offers a review of challenges that university laboratory preschools face in providing a site for research that fits with other components of the program mission. An argument is made to consider paradigm shifts in research questions and methods that move away from traditions within the fields that study children's…

  14. Space Station life science research facility - The vivarium/laboratory

    Science.gov (United States)

    Hilchey, J. D.; Arno, R. D.

    1985-01-01

    Research opportunities possible with the Space Station are discussed. The objective of the research program will be study gravity relationships for animal and plant species. The equipment necessary for space experiments including vivarium facilities are described. The cost of the development of research facilities such as the vivarium/laboratory and a bioresearch centrifuge is examined.

  15. Adverse reproduction outcomes among employees working in biomedical research laboratories

    DEFF Research Database (Denmark)

    Wennborg, H.; Bonde, Jens Peter; Stenbeck, M.

    2002-01-01

    , and the database was linked to the medical birth register. The first births of the women were included in the analysis, 249 pregnancies among the women with laboratory work and 613 pregnancies among the women without laboratory tasks. Information about exposure to various laboratory agents was obtained from......Objectives The aim of the study was to investigate reproductive outcomes such as birthweight, preterm births, and postterm births among women working in research laboratories while pregnant. Methods Female university personnel were identified from a source cohort of Swedish laboratory employees......). Results Exposure to laboratory work with solvents was associated with an increased risk of preterm births, the estimated odds ratio (OR) being 3.4 (1.0 work with bacteria was also observed for postterm births (OR 2.7, 1.0 ≤95% confidence interval

  16. Biological and Physical Space Research Laboratory 2002 Science Review

    Science.gov (United States)

    Curreri, P. A. (Editor); Robinson, M. B. (Editor); Murphy, K. L. (Editor)

    2003-01-01

    With the International Space Station Program approaching core complete, our NASA Headquarters sponsor, the new Code U Enterprise, Biological and Physical Research, is shifting its research emphasis from purely fundamental microgravity and biological sciences to strategic research aimed at enabling human missions beyond Earth orbit. Although we anticipate supporting microgravity research on the ISS for some time to come, our laboratory has been vigorously engaged in developing these new strategic research areas.This Technical Memorandum documents the internal science research at our laboratory as presented in a review to Dr. Ann Whitaker, MSFC Science Director, in July 2002. These presentations have been revised and updated as appropriate for this report. It provides a snapshot of the internal science capability of our laboratory as an aid to other NASA organizations and the external scientific community.

  17. 1995 Laboratory-Directed Research and Development Annual report

    Energy Technology Data Exchange (ETDEWEB)

    Cauffman, D.P.; Shoaf, D.L.; Hill, D.A.; Denison, A.B.

    1995-12-31

    The Laboratory-Directed Research and Development Program (LDRD) is a key component of the discretionary research conducted by Lockheed Idaho Technologies Company (Lockheed Idaho) at the Idaho National Engineering Laboratory (INEL). The threefold purpose and goal of the LDRD program is to maintain the scientific and technical vitality of the INEL, respond to and support new technical opportunities, and enhance the agility and flexibility of the national laboratory and Lockheed Idaho to address the current and future missions of the Department of Energy.

  18. Evaluation of Radiometers in Full-Time Use at the National Renewable Energy Laboratory Solar Radiation Research Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Wilcox, S. M.; Myers, D. R.

    2008-12-01

    This report describes the evaluation of the relative performance of the complement of solar radiometers deployed at the National Renewable Energy Laboratory (NREL) Solar Radiation Research Laboratory (SRRL).

  19. Laboratory Directed Research and Development Program Assessment for FY 2008

    Energy Technology Data Exchange (ETDEWEB)

    Looney, J P; Fox, K J

    2008-03-31

    Brookhaven National Laboratory (BNL) is a multidisciplinary Laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal Year 2008 spending was $531.6 million. There are approximately 2,800 employees, and another 4,300 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development,' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. To be a premier scientific Laboratory, BNL must continuously foster groundbreaking scientific research and renew its research agenda. The competition for LDRD funds stimulates Laboratory scientists to think in new and creative ways, which becomes a major factor in achieving and maintaining research excellence and a means to address National needs within the overall mission of the DOE and BNL. By fostering high-risk, exploratory research, the LDRD program helps

  20. Laboratory directed research and development annual report: Fiscal year 1992

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    The Department of Energy Order DOE 5000.4A establishes DOE's policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 5000.4A, LDRD is research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this order. Consistent with the Mission Statement and Strategic Plan provided in PNL's Institutional Plan, the LDRD investments are focused on developing new and innovative approaches to research related to our core competencies.'' Currently, PNL's core competencies have been identified as: integrated environmental research; process science and engineering; energy distribution and utilization. In this report, the individual summaries of Laboratory-level LDRD projects are organized according to these corecompetencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. The projects described in this report represent PNL's investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. The report provides an overview of PNL's LDRD program and the management process used for the program and project summaries for each LDRD project.

  1. Laboratory directed research and development annual report: Fiscal year 1992

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    The Department of Energy Order DOE 5000.4A establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 5000.4A, LDRD is ``research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this order. Consistent with the Mission Statement and Strategic Plan provided in PNL`s Institutional Plan, the LDRD investments are focused on developing new and innovative approaches to research related to our ``core competencies.`` Currently, PNL`s core competencies have been identified as: integrated environmental research; process science and engineering; energy distribution and utilization. In this report, the individual summaries of Laboratory-level LDRD projects are organized according to these corecompetencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. The projects described in this report represent PNL`s investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. The report provides an overview of PNL`s LDRD program and the management process used for the program and project summaries for each LDRD project.

  2. 76 FR 19188 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2011-04-06

    ... AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development... Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit... DC/Silver Spring. Oncology June 9-10, 2011........ L'Enfant Plaza Hotel. ] Immunology June 9, 2011 L...

  3. 78 FR 66992 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2013-11-07

    ... AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development... Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit... Medicine........ November 25, 2013 *VA Central Office. Neurobiology-F November 26, 2013 *VA Central Office...

  4. Laboratory Directed Research and Development annual report, Fiscal year 1993

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-01

    The Department of Energy Order DOE 5000.4A establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 5000.4A, LDRD is ``research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this Order. LDRD includes activities previously defined as ER&D, as well as other discretionary research and development activities not provided for in a DOE program.`` Consistent with the Mission Statement and Strategic Plan provided in PNL`s Institutional Plan, the LDRD investments are focused on developing new and innovative approaches in research related to our ``core competencies.`` Currently, PNL`s core competencies have been identified as integrated environmental research; process technology; energy systems research. In this report, the individual summaries of Laboratory-level LDRD projects are organized according to these core competencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. A significant proportion of PNL`s LDRD funds are also allocated to projects within the various research centers that are proposed by individual researchers or small research teams. The projects are described in Section 2.0. The projects described in this report represent PNL`s investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. In accordance with DOE guidelines, the report provides an overview of PNL`s LDRD program and the management process used for the program and project summaries for each LDRD project.

  5. LABORATORY DIRECTED RESEARCH AND DEVELOPMENT PROGRAM ASSESSMENT FOR FY 2006.

    Energy Technology Data Exchange (ETDEWEB)

    FOX,K.J.

    2006-01-01

    Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's total annual budget has averaged about $460 million. There are about 2,500 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, ''Laboratory Directed Research and Development,'' April 19,2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy National Nuclear Security Administration Laboratories dated June 13,2006. The goals and' objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new

  6. Laboratory Directed Research and Development Program Assessment for FY 2007

    Energy Technology Data Exchange (ETDEWEB)

    Newman,L.; Fox, K.J.

    2007-12-31

    Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal Year 2007 spending was $515 million. There are approximately 2,600 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development', April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology ideas, which

  7. AIDS--safety practices for clinical and research laboratories.

    Science.gov (United States)

    Federico, J V; Gershon, R R

    1984-04-01

    Acquired immunodeficiency syndrome, or AIDS, is currently a significant health problem receiving widespread interest as both cause and treatment are sought. Indications are that a transmissible agent is involved. Both clinical and research laboratories are receiving greater numbers of specimens from AIDS patients as both prevalence of the condition increases and research efforts intensify. Until such time as the causative agent is identified, prudent practice warrants that a high level of precaution be observed. The Division of Occupational and Environmental Health Services of the Yale University Health Services presents a set of safety procedures and guidelines for use by personnel of both clinical and research laboratory facilities. These exceed previously suggested containment recommendations.

  8. Experimental forests and ranges : 100 years of research success stories

    Science.gov (United States)

    Gail Wells; Deborah Hayes; Katrina Krause; Ann Bartuska; Susan LeVan-Green; Jim Anderson; Tivoli Gough; Mary Adams; Thomas Schuler; Randy Kolka; Steve Sebestyen; Laura Kenefic; John Brissette; Susan Stout; Keith Kanoti; Fred Swanson; Sarah Greene; Margaret Herring; Martin Ritchie; Carl Skinner; Tom Lisle; Elizabeth Keppeler; Leslie Reid; Peter Wohlegemuth; Stanley Kitchen; Ward McCaughey; Jim Guldin; Don Bragg; Michael Shelton; David Loftis; Cathryn Greenberg; Julia Murphy

    2009-01-01

    In 2008, Forest Service Research and Development celebrated the Centennial Anniversary of these Experimental Forests and Ranges. This publication celebrates the many scientists who over the course of decades conducted the long-term studies that began and are continuing to shed light on important natural resource issues. Story suggestions were solicited from the...

  9. Research Collaborations Between Universities and Department of Defense Laboratories

    Science.gov (United States)

    2014-07-31

    collaborative research. The guidebook, reproduced in this document as Appendix D, is a primer for universities that seek to establish a collaborative...extramural funding program managers (PMs) can also retain joint appointments (which include formalized processes for managing COIs ) with universities ...IDA Document D-5230 July 2014 Research Collaborations Between Universities and Department of Defense Laboratories Nayanee Gupta Brian J. Sergi Emma

  10. Integrating Interdisciplinary Research-Based Experiences in Biotechnology Laboratories

    Science.gov (United States)

    Iyer, Rupa S.; Wales, Melinda E.

    2012-01-01

    The increasingly interdisciplinary nature of today's scientific research is leading to the transformation of undergraduate education. In addressing these needs, the University of Houston's College of Technology has developed a new interdisciplinary research-based biotechnology laboratory curriculum. Using the pesticide degrading bacterium,…

  11. Laboratory directed research and development. FY 1995 progress report

    Energy Technology Data Exchange (ETDEWEB)

    Vigil, J.; Prono, J. [comps.

    1996-03-01

    This document presents an overview of Laboratory Directed Research and Development Programs at Los Alamos. The nine technical disciplines in which research is described include materials, engineering and base technologies, plasma, fluids, and particle beams, chemistry, mathematics and computational science, atmic and molecular physics, geoscience, space science, and astrophysics, nuclear and particle physics, and biosciences. Brief descriptions are provided in the above programs.

  12. Field Research Studying Whales in an Undergraduate Animal Behavior Laboratory

    Science.gov (United States)

    MacLaren, R. David; Schulte, Dianna; Kennedy, Jen

    2012-01-01

    This work describes a new field research laboratory in an undergraduate animal behavior course involving the study of whale behavior, ecology and conservation in partnership with a non-profit research organization--the Blue Ocean Society for Marine Conservation (BOS). The project involves two weeks of training and five weekend trips on whale watch…

  13. Use of laboratory animals in biomedical and behavioral research

    National Research Council Canada - National Science Library

    1988-01-01

    ... of Laboratory Animals in Biomedical and Behavioral Research Commission on Life Sciences National Research Council Institute of Medicine NATIONAL ACADEMY PRESS Washington, D.C. 1988 Copyrightoriginal retained, the be not from cannot book, paper original however, for version formatting, authoritative the typesetting-specific created from the as publ...

  14. 76 FR 24974 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2011-05-03

    ... AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development... following four panels of the Joint Biomedical Laboratory Research and Development and Clinical Science... 5, 2011..... 6 p.m.-10 p.m.... Crowne Plaza DC/Silver Spring. Medicine. June 6, 2011..... 8 a.m.-5 p...

  15. A Research-Based Laboratory Course Designed to Strengthen the Research-Teaching Nexus

    Science.gov (United States)

    Parra, Karlett J.; Osgood, Marcy P.; Pappas, Donald L., Jr.

    2010-01-01

    We describe a 10-week laboratory course of guided research experiments thematically linked by topic, which had an ultimate goal of strengthening the undergraduate research-teaching nexus. This undergraduate laboratory course is a direct extension of faculty research interests. From DNA isolation, characterization, and mutagenesis, to protein…

  16. Catalog of Research Abstracts, 1993: Partnership opportunities at Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The 1993 edition of Lawrence Berkeley Laboratory`s Catalog of Research Abstracts is a comprehensive listing of ongoing research projects in LBL`s ten research divisions. Lawrence Berkeley Laboratory (LBL) is a major multi-program national laboratory managed by the University of California for the US Department of Energy (DOE). LBL has more than 3000 employees, including over 1000 scientists and engineers. With an annual budget of approximately $250 million, LBL conducts a wide range of research activities, many that address the long-term needs of American industry and have the potential for a positive impact on US competitiveness. LBL actively seeks to share its expertise with the private sector to increase US competitiveness in world markets. LBL has transferable expertise in conservation and renewable energy, environmental remediation, materials sciences, computing sciences, and biotechnology, which includes fundamental genetic research and nuclear medicine. This catalog gives an excellent overview of LBL`s expertise, and is a good resource for those seeking partnerships with national laboratories. Such partnerships allow private enterprise access to the exceptional scientific and engineering capabilities of the federal laboratory systems. Such arrangements also leverage the research and development resources of the private partner. Most importantly, they are a means of accessing the cutting-edge technologies and innovations being discovered every day in our federal laboratories.

  17. 2014 Fermilab Laboratory Directed Research & Development Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Wester, W., editor

    2016-05-26

    Fermilab is executing Laboratory Directed Research and Development (LDRD) as outlined by order DOE O 413.2B in order to enhance and realize the mission of the laboratory in a manner that also supports the laboratory’s strategic objectives and the mission of the Department of Energy. LDRD funds enable scientific creativity, allow for exploration of “high risk, high payoff” research, and allow for the demonstration of new ideas, technical concepts, and devices. LDRD also has an objective of maintaining and enhancing the scientific and technical vitality of Fermilab.

  18. 2015 Fermilab Laboratory Directed Research & Development Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Wester, W., editor

    2015-05-26

    Fermilab is executing Laboratory Directed Research and Development (LDRD) as outlined by order DOE O 413.2B in order to enhance and realize the mission of the laboratory in a manner that also supports the laboratory’s strategic objectives and the mission of the Department of Energy. LDRD funds enable scientific creativity, allow for exploration of “high risk, high payoff” research, and allow for the demonstration of new ideas, technical concepts, and devices. LDRD also has an objective of maintaining and enhancing the scientific and technical vitality of Fermilab.

  19. Space Station Freedom: a unique laboratory for gravitational biology research

    Science.gov (United States)

    Phillips, R. W.; Cowing, K. L.

    1993-01-01

    The advent of Space Station Freedom (SSF) will provide a permanent laboratory in space with unparalleled opportunities to perform biological research. As with any spacecraft there will also be limitations. It is our intent to describe this space laboratory and present a picture of how scientists will conduct research in this unique environment we call space. SSF is an international venture which will continue to serve as a model for other peaceful international efforts. It is hoped that as the human race moves out from this planet back to the moon and then on to Mars that SSF can serve as a successful example of how things can and should be done.

  20. Adverse pregnancy outcomes in offspring of fathers working in biomedical research laboratories

    DEFF Research Database (Denmark)

    Magnusson, Linda L; Bodin, Lennart; Wennborg, Helena

    2006-01-01

    BACKGROUND: Laboratory work may constitute a possible health hazard for workers as well as for their offspring, and involves a wide range of exposures, such as organic solvents, carcinogenic agents, ionizing radiation, and/or microbiological agents. Adverse pregnancy outcomes in the offspring...... of male employees in biomedical research laboratories are examined. METHODS: Offspring to males employed 1970-1989 at four Swedish universities were identified via the Medical Birth Register (MBR), along with other pregnancy parameters. Offspring of fathers with laboratory work (n = 2,281) is considered...... exposed, and of non-laboratory employees unexposed (n = 1,909). Exposure data were obtained by questionnaires to research group leaders. Logistic regression analysis estimated odds ratios (ORs) and 95% confidence intervals (CIs). RESULTS: Paternal laboratory work in general showed no statistically...

  1. Argonne National Laboratory Annual Report of Laboratory Directed Research and Development Program Activities for FY 1994

    Energy Technology Data Exchange (ETDEWEB)

    None

    1995-02-25

    The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory's R and D capabilities, and further the development of its strategic initiatives. Projects are selected from proposals for creative and innovative R and D studies which are not yet eligible for timely support through normal programmatic channels. Among the aims of the projects supported by the Program are establishment of engineering proof-of-principle; assessment of design feasibility for prospective facilities; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these projects are closely associated with major strategic thrusts of the Laboratory as described in Argonne's Five-Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne as indicated in the Laboratory's LDRD Plan for FY 1994. Project summaries of research in the following areas are included: (1) Advanced Accelerator and Detector Technology; (2) X-ray Techniques for Research in Biological and Physical Science; (3) Nuclear Technology; (4) Materials Science and Technology; (5) Computational Science and Technology; (6) Biological Sciences; (7) Environmental Sciences: (8) Environmental Control and Waste Management Technology; and (9) Novel Concepts in Other Areas.

  2. 2015 Fermilab Laboratory Directed Research & Development Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Wester, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2016-05-26

    The Fermi National Accelerator Laboratory (FNAL) is conducting a Laboratory Directed Research and Development (LDRD) program. Fiscal year 2015 represents the first full year of LDRD at Fermilab and includes seven projects approved mid-year in FY14 and six projects approved in FY15. One of the seven original projects has been completed just after the beginning of FY15. The implementation of LDRD at Fermilab is captured in the approved Fermilab 2015 LDRD Annual Program Plan. In FY15, the LDRD program represents 0.64% of Laboratory funding. The scope of the LDRD program at Fermilab will be established over the next couple of years where a portfolio of about 20 on-going projects representing approximately between 1% and 1.5% of the Laboratory funding is anticipated. This Annual Report focuses on the status of the current projects and provides an overview of the current status of LDRD at Fermilab.

  3. Laboratory Directed Research and Development Program FY 2007 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Sjoreen, Terrence P [ORNL

    2008-04-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries for all ORNL LDRD research activities supported during FY 2007. The associated FY 2007 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching mission to advance the national, economic, and energy security of the United States and promote scientific and technological innovation in support of that mission. As a national resource, the Laboratory also applies its capabilities and skills to specific needs of other federal agencies and customers through the DOE Work for Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at http://www.ornl.gov/. LDRD is a relatively small but vital DOE program that allows ORNL, as well as other DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the Laboratory; (2) enhancing the Laboratory's ability to address future DOE missions; (3) fostering creativity and stimulating

  4. Laboratory Directed Research and Development Program FY 2005 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Sjoreen, Terrence P [ORNL

    2006-04-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2A, 'Laboratory Directed Research and Development' (January 8, 2001), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report describes all ORNL LDRD research activities supported during FY 2005 and includes final reports for completed projects and shorter progress reports for projects that were active, but not completed, during this period. The FY 2005 ORNL LDRD Self-Assessment (ORNL/PPA-2006/2) provides financial data about the FY 2005 projects and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching national security mission, which encompasses science, energy resources, environmental quality, and national nuclear security. As a national resource, the Laboratory also applies its capabilities and skills to the specific needs of other federal agencies and customers through the DOE Work For Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at . LDRD is a relatively small but vital DOE program that allows ORNL, as well as other multiprogram DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the

  5. Laboratory Directed Research and Development Program FY 2004 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Sjoreen, Terrence P [ORNL

    2005-04-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2A, 'Laboratory Directed Research and Development' (January 8, 2001), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report describes all ORNL LDRD research activities supported during FY 2004 and includes final reports for completed projects and shorter progress reports for projects that were active, but not completed, during this period. The FY 2004 ORNL LDRD Self-Assessment (ORNL/PPA-2005/2) provides financial data about the FY 2004 projects and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching national security mission, which encompasses science, energy resources, environmental quality, and national nuclear security. As a national resource, the Laboratory also applies its capabilities and skills to the specific needs of other federal agencies and customers through the DOE Work For Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at . LDRD is a relatively small but vital DOE program that allows ORNL, as well as other multiprogram DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the

  6. Laboratory directed research and development annual report. Fiscal year 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-02-01

    The Department of Energy Order DOE 5000.4A establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. This report represents Pacific Northwest Laboratory`s (PNL`s) LDRD report for FY 1994. During FY 1994, 161 LDRD projects were selected for support through PNL`s LDRD project selection process. Total funding allocated to these projects was $13.7 million. Consistent with the Mission Statement and Strategic Plan provided in PNL`s Institutional Plan, the LDRD investments are focused on developing new and innovative approaches in research related to our {open_quotes}core competencies.{close_quotes} Currently, PNL`s core competencies have been identified as integrated environmental research; process science and engineering; energy systems development. In this report, the individual summaries of LDRD projects (presented in Section 1.0) are organized according to these core competencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. Projects within the three core competency areas were approximately 91.4 % of total LDRD project funding at PNL in FY 1994. A significant proportion of PNL`s LDRD funds are also allocated to projects within the various research centers that are proposed by individual researchers or small research teams. Funding allocated to each of these projects is typically $35K or less. The projects described in this report represent PNL`s investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. The report provides an overview of PNL`s LDRD program, the management process used for the program, and project summaries for each LDRD project.

  7. Laboratory Directed Research and Development Program Activities for FY 2008.

    Energy Technology Data Exchange (ETDEWEB)

    Looney,J.P.; Fox, K.

    2009-04-01

    Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that maintains a primary mission focus the physical sciences, energy sciences, and life sciences, with additional expertise in environmental sciences, energy technologies, and national security. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal year 2008 budget was $531.6 million. There are about 2,800 employees, and another 4,300 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development,' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Developlnent at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. Accordingly, this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2008. BNL expended $12 million during Fiscal Year 2008 in support of 69 projects. The program has two categories, the annual Open Call LDRDs and Strategic LDRDs, which combine to meet the overall objectives of the LDRD Program. Proposals are solicited annually for review and approval concurrent with the next fiscal year, October 1. For the open call for proposals, an LDRD Selection Committee, comprised of the Associate Laboratory Directors (ALDs) for the Scientific Directorates, an equal number of scientists recommended by the Brookhaven Council, plus the Assistant Laboratory Director for Policy and Strategic Planning, review the proposals submitted in response to the solicitation. The Open Can LDRD category emphasizes innovative research concepts

  8. Integrating teaching and research in the field and laboratory settings

    Science.gov (United States)

    Wang, L.; Kaseke, K. F.; Daryanto, S.; Ravi, S.

    2015-12-01

    Field observations and laboratory measurements are great ways to engage students and spark students' interests in science. Typically these observations are separated from rigorous classroom teaching. Here we assessed the potential of integrating teaching and research in the field and laboratory setting in both US and abroad and worked with students without strong science background to utilize simple laboratory equipment and various environmental sensors to conduct innovative projects. We worked with students in Namibia and two local high school students in Indianapolis to conduct leaf potential measurements, soil nutrient extraction, soil infiltration measurements and isotope measurements. The experience showed us the potential of integrating teaching and research in the field setting and working with people with minimum exposure to modern scientific instrumentation to carry out creative projects.

  9. The Los Alamos Scientific Laboratory - An Isolated Nuclear Research Establishment

    Energy Technology Data Exchange (ETDEWEB)

    Bradbury, Norris E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Meade, Roger Allen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-09-23

    Early in his twenty-five year career as the Director of the Los Alamos Scientific Laboratory, Norris Bradbury wrote at length about the atomic bomb and the many implications the bomb might have on the world. His themes were both technical and philosophical. In 1963, after nearly twenty years of leading the nation’s first nuclear weapons laboratory, Bradbury took the opportunity to broaden his writing. In a paper delivered to the International Atomic Energy Agency’s symposium on the “Criteria in the Selection of Sites for the Construction of Reactors and Nuclear Research Centers,” Bradbury took the opportunity to talk about the business of nuclear research and the human component of operating a scientific laboratory. This report is the transcript of his talk.

  10. Laboratory directed research and development: FY 1997 progress report

    Energy Technology Data Exchange (ETDEWEB)

    Vigil, J.; Prono, J. [comps.

    1998-05-01

    This is the FY 1997 Progress Report for the Laboratory Directed Research and Development (LDRD) program at Los Alamos National Laboratory. It gives an overview of the LDRD program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic and molecular physics and plasmas, fluids, and particle beams, (5) engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.

  11. Laboratory Directed Research and Development FY 1998 Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    John Vigil; Kyle Wheeler

    1999-04-01

    This is the FY 1998 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principle investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5) engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.

  12. Argonne National Laboratory: Laboratory Directed Research and Development FY 1993 program activities. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1993-12-23

    The purposes of Argonne`s Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory`s R&D capabilities, and further the development of its strategic initiatives. Projects are selected from proposals for creative and innovative R&D studies which are not yet eligible for timely support through normal programmatic channels. Among the aims of the projects supported by the Program are establishment of engineering ``proof-of-principle`` assessment of design feasibility for prospective facilities; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these projects are closely associated with major strategic thrusts of the Laboratory as described in Argonne`s Five Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne as indicated in the Laboratory LDRD Plan for FY 1993.

  13. Laboratory Directed Research and Development FY2008 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Kammeraad, J E; Jackson, K J; Sketchley, J A; Kotta, P R

    2009-03-24

    The Laboratory Directed Research and Development (LDRD) Program, authorized by Congress in 1991 and administered by the Institutional Science and Technology Office at Lawrence Livermore, is our primary means for pursuing innovative, long-term, high-risk, and potentially high-payoff research that supports the full spectrum of national security interests encompassed by the missions of the Laboratory, the Department of Energy, and National Nuclear Security Administration. The accomplishments described in this annual report demonstrate the strong alignment of the LDRD portfolio with these missions and contribute to the Laboratory's success in meeting its goals. The LDRD budget of $91.5 million for fiscal year 2008 sponsored 176 projects. These projects were selected through an extensive peer-review process to ensure the highest scientific quality and mission relevance. Each year, the number of deserving proposals far exceeds the funding available, making the selection a tough one indeed. Our ongoing investments in LDRD have reaped long-term rewards for the Laboratory and the nation. Many Laboratory programs trace their roots to research thrusts that began several years ago under LDRD sponsorship. In addition, many LDRD projects contribute to more than one mission area, leveraging the Laboratory's multidisciplinary team approach to science and technology. Safeguarding the nation from terrorist activity and the proliferation of weapons of mass destruction will be an enduring mission of this Laboratory, for which LDRD will continue to play a vital role. The LDRD Program is a success story. Our projects continue to win national recognition for excellence through prestigious awards, papers published in peer-reviewed journals, and patents granted. With its reputation for sponsoring innovative projects, the LDRD Program is also a major vehicle for attracting and retaining the best and the brightest technical staff and for establishing collaborations with

  14. Laboratory directed research development annual report. Fiscal year 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-05-01

    This document comprises Pacific Northwest National Laboratory`s report for Fiscal Year 1996 on research and development programs. The document contains 161 project summaries in 16 areas of research and development. The 16 areas of research and development reported on are: atmospheric sciences, biotechnology, chemical instrumentation and analysis, computer and information science, ecological science, electronics and sensors, health protection and dosimetry, hydrological and geologic sciences, marine sciences, materials science and engineering, molecular science, process science and engineering, risk and safety analysis, socio-technical systems analysis, statistics and applied mathematics, and thermal and energy systems. In addition, this report provides an overview of the research and development program, program management, program funding, and Fiscal Year 1997 projects.

  15. On the Use of a Range Trigger for the Mars Science Laboratory Entry Descent and Landing

    Science.gov (United States)

    Way, David W.

    2011-01-01

    In 2012, during the Entry, Descent, and Landing (EDL) of the Mars Science Laboratory (MSL) entry vehicle, a 21.5 m Viking-heritage, Disk-Gap-Band, supersonic parachute will be deployed at approximately Mach 2. The baseline algorithm for commanding this parachute deployment is a navigated planet-relative velocity trigger. This paper compares the performance of an alternative range-to-go trigger (sometimes referred to as Smart Chute ), which can significantly reduce the landing footprint size. Numerical Monte Carlo results, predicted by the POST2 MSL POST End-to-End EDL simulation, are corroborated and explained by applying propagation of uncertainty methods to develop an analytic estimate for the standard deviation of Mach number. A negative correlation is shown to exist between the standard deviations of wind velocity and the planet-relative velocity at parachute deploy, which mitigates the Mach number rise in the case of the range trigger.

  16. LBNL Laboratory Directed Research and Development Program FY2016

    Energy Technology Data Exchange (ETDEWEB)

    Ho, D.

    2017-03-01

    The Berkeley Lab Laboratory Directed Research and Development Program FY2016 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the supported projects and summarizes their accomplishments. It constitutes a part of the LDRD program planning and documentation process that includes an annual planning cycle, project selection, implementation and review.

  17. Fermilab a laboratory at the frontier of research

    CERN Document Server

    Gillies, James D

    2002-01-01

    Since its foundation in 1967, creeping urbanization has taken away some of Fermilab's remoteness, but the famous buffalo still roam, and farm buildings evocative of frontier America dot the landscape - appropriately for a laboratory at the high-energy frontier of modern research. Topics discussed are the Tevatron, detector upgrades, the neutrino programme, Fermilab and the LHC and the non-accelerator programme.

  18. Laboratory Research: A Question of When, Not If.

    Science.gov (United States)

    1985-03-01

    possible in the field, and feasibility. * ... SJAN 1473 EDITION Of’ I NOV Of IS OSOLETE UNCLASSIFIED * S/N 0102- LF-014- 6601 SECURITY CLASIFICATION OF...generalized to adult members of the workforce. In attempts to answer critics, some laboratory researchers have used business school students instead of those

  19. Laboratory Directed Research and Development LDRD-FY-2011

    Energy Technology Data Exchange (ETDEWEB)

    Dena Tomchak

    2012-03-01

    This report provides a summary of the research conducted at the Idaho National Laboratory (INL) during Fiscal Year (FY) 2011. This report demonstrates the types of cutting edge research the INL is performing to help ensure the nation's energy security. The research conducted under this program is aligned with our strategic direction, benefits the Department of Energy (DOE) and is in compliance with DOE order 413.2B. This report summarizes the diverse research and development portfolio with emphasis on the DOE Office of Nuclear Energy (DOE-NE) mission, encompassing both advanced nuclear science and technology and underlying technologies.

  20. 78 FR 28292 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2013-05-14

    ... AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development... location changes have been made for the following panel meetings of the of the Joint Biomedical Laboratory..., 2013; Pulmonary Medicine will meet on May 30, 2013, at the Sheraton Crystal City Hotel and not on May...

  1. Laboratory directed research and development program FY 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This report compiles the annual reports of Laboratory Directed Research and Development projects supported by the Berkeley Lab. Projects are arranged under the following topical sections: (1) Accelerator and fusion research division; (2) Chemical sciences division; (3) Computing Sciences; (4) Earth sciences division; (5) Environmental energy technologies division; (6) life sciences division; (7) Materials sciences division; (8) Nuclear science division; (9) Physics division; (10) Structural biology division; and (11) Cross-divisional. A total of 66 projects are summarized.

  2. Catalog of research projects at Lawrence Berkeley Laboratory, 1985

    Energy Technology Data Exchange (ETDEWEB)

    1985-01-01

    This Catalog has been created to aid in the transfer of technology from the Lawrence Berkeley Laboratory to potential users in industry, government, universities, and the public. The projects are listed for the following LBL groups: Accelerator and Fusion Research Division, Applied Science Division, Biology and Medicine Division, Center for Advanced Materials, Chemical Biodynamics Division, Computing Division, Earth Sciences Division, Engineering and Technical Services Division, Materials and Molecular Research Division, Nuclear Science Division, and Physics Division.

  3. Laboratory Directed Research and Development Program Activities for FY 2007.

    Energy Technology Data Exchange (ETDEWEB)

    Newman,L.

    2007-12-31

    Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal year 2007 budget was $515 million. There are about 2,600 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development', April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. In accordance this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2007. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. We explicitly indicate that research conducted under the LDRD Program should be highly innovative, and an element of high risk as to success is acceptable. In the solicitation for new proposals for Fiscal Year 2007 we especially requested innovative new projects in

  4. Laboratory-Directed Research and Development 2016 Summary Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Pillai, Rekha Sukamar [Idaho National Lab. (INL), Idaho Falls, ID (United States); Jacobson, Julie Ann [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-01-01

    The Laboratory-Directed Research and Development (LDRD) Program at Idaho National Laboratory (INL) reports its status to the U.S. Department of Energy (DOE) by March of each year. The program operates under the authority of DOE Order 413.2C, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the laboratory director broad flexibility for program implementation. LDRD funds are obtained through a charge to all INL programs. This report includes summaries of all INL LDRD research activities supported during Fiscal Year (FY) 2016. INL is the lead laboratory for the DOE Office of Nuclear Energy (DOE-NE). The INL mission is to discover, demonstrate, and secure innovative nuclear energy solutions, other clean energy options, and critical infrastructure with a vision to change the world’s energy future and secure our critical infrastructure. Operating since 1949, INL is the nation’s leading research, development, and demonstration center for nuclear energy, including nuclear nonproliferation and physical and cyber-based protection of energy systems and critical infrastructure, as well as integrated energy systems research, development, demonstration, and deployment. INL has been managed and operated by Battelle Energy Alliance, LLC (a wholly owned company of Battelle) for DOE since 2005. Battelle Energy Alliance, LLC, is a partnership between Battelle, BWX Technologies, Inc., AECOM, the Electric Power Research Institute, the National University Consortium (Massachusetts Institute of Technology, Ohio State University, North Carolina State University, University of New Mexico, and Oregon State University), and the Idaho university collaborators (i.e., University of Idaho, Idaho State University, and Boise State University). Since its creation, INL’s research and development (R&D) portfolio has broadened with targeted programs supporting national missions to advance nuclear energy

  5. Laboratory directed research and development fy1999 annual report

    Energy Technology Data Exchange (ETDEWEB)

    Al-Ayat, R A

    2000-04-11

    The Lawrence Livermore National Laboratory (LLNL) was founded in 1952 and has been managed since its inception by the University of California (UC) for the U.S. Department of Energy (DOE). Because of this long association with UC, the Laboratory has been able to recruit a world-class workforce, establish an atmosphere of intellectual freedom and innovation, and achieve recognition in relevant fields of knowledge as a scientific and technological leader. This environment and reputation are essential for sustained scientific and technical excellence. As a DOE national laboratory with about 7,000 employees, LLNL has an essential and compelling primary mission to ensure that the nation's nuclear weapons remain safe, secure, and reliable and to prevent the spread and use of nuclear weapons worldwide. The Laboratory receives funding from the DOE Assistant Secretary for Defense Programs, whose focus is stewardship of our nuclear weapons stockpile. Funding is also provided by the Deputy Administrator for Defense Nuclear Nonproliferation, many Department of Defense sponsors, other federal agencies, and the private sector. As a multidisciplinary laboratory, LLNL has applied its considerable skills in high-performance computing, advanced engineering, and the management of large research and development projects to become the science and technology leader in those areas of its mission responsibility. The Laboratory Directed Research and Development (LDRD) Program was authorized by the U.S. Congress in 1984. The Program allows the Director of each DOE laboratory to fund advanced, creative, and innovative research and development (R&D) activities that will ensure scientific and technical vitality in the continually evolving mission areas at DOE and the Laboratory. In addition, the LDRD Program provides LLNL with the flexibility to nurture and enrich essential scientific and technical competencies, which attract the most qualified scientists and engineers. The LDRD Program

  6. Laboratory Directed Research and Development Program. FY 1993

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    This report is compiled from annual reports submitted by principal investigators following the close of fiscal year 1993. This report describes the projects supported and summarizes their accomplishments. The program advances the Laboratory`s core competencies, foundations, scientific capability, and permits exploration of exciting new opportunities. Reports are given from the following divisions: Accelerator and Fusion Research, Chemical Sciences, Earth Sciences, Energy and Environment, Engineering, Environment -- Health and Safety, Information and Computing Sciences, Life Sciences, Materials Sciences, Nuclear Science, Physics, and Structural Biology. (GHH)

  7. Laboratory Directed Research and Development Program FY98

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, T. [ed.; Chartock, M.

    1999-02-05

    The Ernest Orlando Lawrence Berkeley National Laboratory (LBNL or Berkeley Lab) Laboratory Directed Research and Development Program FY 1998 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the supported projects and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The LBNL LDRD program is a critical tool for directing the Laboratory's forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for LBNL scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances LBNL's core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. All projects are work in forefront areas of science and technology. Areas eligible for support include the following: Advanced study of hypotheses, concepts, or innovative approaches to scientific or technical problems; Experiments and analyses directed toward ''proof of principle'' or early determination of the utility of new scientific ideas, technical concepts, or devices; and Conception and preliminary technical analyses of experimental facilities or devices.

  8. Laboratory Directed Research and Development Program. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    Ogeka, G.J.

    1991-12-01

    Today, new ideas and opportunities, fostering the advancement of technology, are occurring at an ever-increasing rate. It, therefore, seems appropriate that a vehicle be available which fosters the development of these new ideas and technologies, promotes the early exploration and exploitation of creative and innovative concepts, and which develops new ``fundable`` R&D projects and programs. At Brookhaven National Laboratory (BNL), one such method is through its Laboratory Directed Research and Development (LDRD) Program. This discretionary research and development tool is critical in maintaining the scientific excellence and vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor achieving and maintaining staff excellence, and a means to address national needs, with the overall mission of the Department of Energy (DOE) and the Brookhaven National Laboratory. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, they have resulted in numerous publications in various professional and scientific journals, and presentations at meetings and forums.

  9. LABORATORY DIRECTED RESEARCH AND DEVELOPMENT PROGRAM ACTIVITIES FOR FY2002.

    Energy Technology Data Exchange (ETDEWEB)

    FOX,K.J.

    2002-12-31

    Brookhaven National (BNL) Laboratory is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, under contract with the U. S. Department of Energy. BNL's total annual budget has averaged about $450 million. There are about 3,000 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 4 1 3.2A, ''Laboratory Directed Research and Development,'' January 8, 2001, and the LDRD Annual Report guidance, updated February 12, 1999. The LDRD Program obtains its funds through the Laboratory overhead pool and operates under the authority of DOE Order 413.2A. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology

  10. Foraminiferal Range Expansions: The Mediterranean Sea as a natural laboratory for climate induced invasions

    Science.gov (United States)

    Hortense Mouanga, Gloria; Langer, Martin R.

    2015-04-01

    Climate change and biological invasions are key processes that modify biodiversity. One of the most severely affected areas of global change is the Mediterranean Sea, where global warming and the opening of the Suez Canal triggered a mass invasion of tropical Red Sea taxa into Mediterranean territories. Climate models prognosticate that the Mediterranean Sea will be one of the most affected ocean regions and may thus serve as a natural laboratory of future global changes. Among the key taxa that are rapidly expanding their latitudinal range in the Mediterranean Sea are symbiont-bearing foraminifera of the genus Amphistegina. Their range expansion strongly correlates with rising sea surface temperatures and mirrors processes of global change. Amphisteginid foraminifera are among the most prolific foraminiferal species and contribute significantly to shallow-water carbonate sediments. Given their prominent environmental role, rapid biogeographic range expansion, and impact on native ecosystems, amphisteginid range expansion and invasion into new territory are likely to trigger changes in ecosystem functioning. Among the uncertainties, it is not known whether all parts of the Mediterranean will be affected equally and to what extent amphisteginid invasions will impact native biotas. We have initiated a new baseline study to explore the effects of invasive amphisteginids on native foraminiferal biotas and to monitor expansion rates and effects on ecosystem functioning along the current range expansion front. We will present new data on recent shift along the range expansion front and discuss cascading effects on community structures and species richness of native foraminiferal biotas. The magnitude and effects that climate change will have on the Mediterranean foraminiferal faunas may ultimately serve as an example of what would happen along expansion fronts in global oceans.

  11. Laboratory Directed Research and Development Program FY 2006

    Energy Technology Data Exchange (ETDEWEB)

    Hansen (Ed.), Todd

    2007-03-08

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness.

  12. Guidelines for euthanasia of laboratory animals used in biomedical research

    Directory of Open Access Journals (Sweden)

    Adina Baias,

    2012-06-01

    Full Text Available Laboratory animals are used in several fields of science research, especially in biology, medicine and veterinary medicine. The majority of laboratory animals used in research are experimental models that replace the human body in study regarding pharmacological or biological safety products, studies conducted for a betterunderstanding of oncologic processes, toxicology, genetic studies or even new surgical techniques. Experimental protocols include a stage in which animals are euthanized in order to remove organs and tissues,or for no unnecessary pain and suffering of animals (humane endpoints or to mark the end of research. The result of euthanasia techniques is a rapid loss of consciousness followed by cardiac arrest, respiratory arrest and disruption of brain activity. Nowadays, the accepted euthanasia techniques can use chemicals (inhalant agents like: carbon dioxide, nitrogen or argon, overdoses of injectable anesthetics or physical methods (decapitation, cervical spine dislocation, stunning, gunshot, pitching.

  13. Laboratory Directed Research and Development FY 2000 Annual Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    Los Alamos National Laboratory

    2001-05-01

    This is the FY00 Annual Progress report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes progress on each project conducted during FY00, characterizes the projects according to their relevance to major funding sources, and provides an index to principal investigators. Project summaries are grouped by LDRD component: Directed Research and Exploratory Research. Within each component, they are further grouped into the ten technical categories: (1) atomic, molecular, optical, and plasma physics, fluids, and beams, (2) bioscience, (3) chemistry, (4) computer science and software engineering, (5) engineering science, (6) geoscience, space science, and astrophysics, (7) instrumentation and diagnostics, (8) materials science, (9) mathematics, simulation, and modeling, and (10) nuclear and particle physics.

  14. FY2007 Laboratory Directed Research and Development Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Craig, W W; Sketchley, J A; Kotta, P R

    2008-03-20

    The Laboratory Directed Research and Development (LDRD) annual report for fiscal year 2007 (FY07) provides a summary of LDRD-funded projects for the fiscal year and consists of two parts: An introduction to the LDRD Program, the LDRD portfolio-management process, program statistics for the year, and highlights of accomplishments for the year. A summary of each project, submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to Department of Energy (DOE)/National Nuclear Security Administration (NNSA) and Lawrence Livermore National Laboratory (LLNL) mission areas, the technical progress achieved in FY07, and a list of publications that resulted from the research in FY07. Summaries are organized in sections by research category (in alphabetical order). Within each research category, the projects are listed in order of their LDRD project category: Strategic Initiative (SI), Exploratory Research (ER), Laboratory-Wide Competition (LW), and Feasibility Study (FS). Within each project category, the individual project summaries appear in order of their project tracking code, a unique identifier that consists of three elements. The first is the fiscal year the project began, the second represents the project category, and the third identifies the serial number of the proposal for that fiscal year.

  15. FY03 Engineering Technology Reports Laboratory Directed Research and Development

    Energy Technology Data Exchange (ETDEWEB)

    Minichino, C

    2004-03-05

    This report summarizes the science and technology research and development efforts in Lawrence Livermore National Laboratory's Engineering Directorate for FY2003, and exemplifies Engineering's 50-year history of researching and developing the engineering technologies needed to support the Laboratory's missions. Engineering has been a partner in every major program and project at the Laboratory throughout its existence, and has prepared for this role with a skilled workforce and the technical resources developed through venues like the Laboratory Directed Research and Development Program (LDRD). This accomplishment is well summarized by Engineering's mission: ''Enable program success today and ensure the Laboratory's vitality tomorrow.'' Engineering's investment in technologies is carried out through two programs, the LDRD program and the ''Tech Base'' program. LDRD is the vehicle for creating those technologies and competencies that are cutting edge, or that require a significant level of research, or contain some unknown that needs to be fully understood. Tech Base is used to apply those technologies, or adapt them to a Laboratory need. The term commonly used for Tech Base projects is ''reduction to practice.'' Therefore, the LDRD report covered here has a strong research emphasis. Areas that are presented all fall into those needed to accomplish our mission. For FY2003, Engineering's LDRD projects were focused on mesoscale target fabrication and characterization, development of engineering computational capability, material studies and modeling, remote sensing and communications, and microtechnology and nanotechnology for national security applications. Engineering's five Centers, in partnership with the Division Leaders and Department Heads, are responsible for guiding the science and technology investments for the Directorate. The Centers represent technology

  16. Pinon-juniper management research at Corona Range and Livestock Research Center in Central New Mexico

    Science.gov (United States)

    Andres Cibils; Mark Petersen; Shad Cox; Michael Rubio

    2008-01-01

    Description: New Mexico State University's Corona Range and Livestock Research Center (CRLRC) is located in a pinon-juniper (PJ)/grassland ecotone in the southern Basin and Range Province in south central New Mexico. A number of research projects conducted at this facility revolve around soil, plant, livestock, and wildlife responses to PJ woodland management. The...

  17. Radiological Characterization and Final Facility Status Report Tritium Research Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, T.B.; Gorman, T.P.

    1996-08-01

    This document contains the specific radiological characterization information on Building 968, the Tritium Research Laboratory (TRL) Complex and Facility. We performed the characterization as outlined in its Radiological Characterization Plan. The Radiological Characterization and Final Facility Status Report (RC&FFSR) provides historic background information on each laboratory within the TRL complex as related to its original and present radiological condition. Along with the work outlined in the Radiological Characterization Plan (RCP), we performed a Radiological Soils Characterization, Radiological and Chemical Characterization of the Waste Water Hold-up System including all drains, and a Radiological Characterization of the Building 968 roof ventilation system. These characterizations will provide the basis for the Sandia National Laboratory, California (SNL/CA) Site Termination Survey .Plan, when appropriate.

  18. Update on Engine Combustion Research at Sandia National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Jay Keller; Gurpreet Singh

    2001-05-14

    The objectives of this paper are to describe the research efforts in diesel engine combustion at Sandia National Laboratories' Combustion Research Facility and to provide recent experimental results. We have four diesel engine experiments supported by the Department of Energy, Office of Heavy Vehicle Technologies: a one-cylinder version of a Cummins heavy-duty engine, a diesel simulation facility, a one-cylinder Caterpillar engine to evaluate combustion of alternative fuels, and a homogeneous-charge, compression ignition (HCCI) engine. Recent experimental results of diesel combustion research will be discussed and a description will be given of our HCCI experimental program and of our HCCI modeling work.

  19. Methodology in diagnostic laboratory test research in clinical chemistry and clinical chemistry and laboratory medicine.

    Science.gov (United States)

    Lumbreras-Lacarra, Blanca; Ramos-Rincón, José Manuel; Hernández-Aguado, Ildefonso

    2004-03-01

    The application of epidemiologic principles to clinical diagnosis has been less developed than in other clinical areas. Knowledge of the main flaws affecting diagnostic laboratory test research is the first step for improving its quality. We assessed the methodologic aspects of articles on laboratory tests. We included articles that estimated indexes of diagnostic accuracy (sensitivity and specificity) and were published in Clinical Chemistry or Clinical Chemistry and Laboratory Medicine in 1996, 2001, and 2002. Clinical Chemistry has paid special attention to this field of research since 1996 by publishing recommendations, checklists, and reviews. Articles were identified through electronic searches in Medline. The strategy combined the Mesh term "sensitivity and specificity" (exploded) with the text words "specificity", "false negative", and "accuracy". We examined adherence to seven methodologic criteria used in the study by Reid et al. (JAMA1995;274:645-51) of papers published in general medical journals. Three observers evaluated each article independently. Seventy-nine articles fulfilled the inclusion criteria. The percentage of studies that satisfied each criterion improved from 1996 to 2002. Substantial improvement was observed in reporting of the statistical uncertainty of indices of diagnostic accuracy, in criteria based on clinical information from the study population (spectrum composition), and in avoidance of workup bias. Analytical reproducibility was reported frequently (68%), whereas information about indeterminate results was rarely provided. The mean number of methodologic criteria satisfied showed a statistically significant increase over the 3 years in Clinical Chemistry but not in Clinical Chemistry and Laboratory Medicine. The methodologic quality of the articles on diagnostic test research published in Clinical Chemistry and Clinical Chemistry and Laboratory Medicine is comparable to the quality observed in the best general medical journals

  20. Research in clinical laboratory science: professionals' educational preparation.

    Science.gov (United States)

    Laudicina, Rebecca; Fenn, JoAnn P; Freeman, Vickie; McCoy, Carol; McLane, Mary Ann; Mundt, Lillian; Polancic, Joan; Randolph, Tim; Shanahan, Kristy

    2011-01-01

    To describe the educational preparation of CLS professionals for conducting research. A link to 3-part online survey was sent by electronic mail to 7,572 members of the American Society for Clinical Laboratory Science and 500 program directors research project. Barriers to participation in research by undergraduates include time limitations within the curriculum, insufficient faculty time, and lack of funds, space, and equipment. Increased emphasis on developing research skills is found in educational programs at the master's degree level. The formal educational background of many CLS professionals may leave them unprepared or underprepared for conducting research. Although there was broad representation among participants across educational levels, employment settings, and job positions, the number of survey respondents was limited. Possible directions for future research include conducting this survey using members of additional professional organizations.

  1. Laboratory Directed Research and Development Program FY2004

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd C.

    2005-03-22

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Goals that are codified in DOE's September 2003 Strategic Plan, with a primary focus on Advancing Scientific Understanding. For that goal, the Fiscal Year (FY) 2004 LDRD projects support every one of the eight strategies described in the plan. In addition, LDRD efforts support the goals of Investing in America's Energy Future (six of the fourteen strategies), Resolving the Environmental Legacy (four of the eight strategies), and Meeting National Security Challenges (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD supports Office of Science strategic plans, including the 20 year Scientific Facilities Plan and the draft Office of Science Strategic Plan. The research also

  2. FY04 Engineering Technology Reports Laboratory Directed Research and Development

    Energy Technology Data Exchange (ETDEWEB)

    Sharpe, R M

    2005-01-27

    This report summarizes the science and technology research and development efforts in Lawrence Livermore National Laboratory's Engineering Directorate for FY2004, and exemplifies Engineering's more than 50-year history of developing the technologies needed to support the Laboratory's missions. Engineering has been a partner in every major program and project at the Laboratory throughout its existence and has prepared for this role with a skilled workforce and the technical resources developed through venues like the Laboratory Directed Research and Development Program (LDRD). This accomplishment is well summarized by Engineering's mission: ''Enable program success today and ensure the Laboratory's vitality tomorrow''. Engineering's investment in technologies is carried out through two programs, the ''Tech Base'' program and the LDRD program. LDRD is the vehicle for creating those technologies and competencies that are cutting edge. These require a significant level of research or contain some unknown that needs to be fully understood. Tech Base is used to apply technologies to a Laboratory need. The term commonly used for Tech Base projects is ''reduction to practice''. Therefore, the LDRD report covered here has a strong research emphasis. Areas that are presented all fall into those needed to accomplish our mission. For FY2004, Engineering's LDRD projects were focused on mesoscale target fabrication and characterization, development of engineering computational capability, material studies and modeling, remote sensing and communications, and microtechnology and nanotechnology for national security applications. Engineering's five Centers, in partnership with the Division Leaders and Department Heads, are responsible for guiding the long-term science and technology investments for the Directorate. The Centers represent technologies that have been identified as

  3. Laboratory directed research and development program FY 1999

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd; Levy, Karin

    2000-03-08

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. This is the annual report on Laboratory Directed Research and Development (LDRD) program for FY99.

  4. Laboratory Directed Research and Development Program FY 2001

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd; Levy, Karin

    2002-03-15

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. This is the annual report on Laboratory Directed Research and Development (LDRD) program for FY01.

  5. Argonne National Laboratory annual report of Laboratory Directed Research and Development Program Activities FY 2009.

    Energy Technology Data Exchange (ETDEWEB)

    Office of the Director

    2010-04-09

    I am pleased to submit Argonne National Laboratory's Annual Report on its Laboratory Directed Research and Development (LDRD) activities for fiscal year 2009. Fiscal year 2009 saw a heightened focus by DOE and the nation on the need to develop new sources of energy. Argonne scientists are investigating many different sources of energy, including nuclear, solar, and biofuels, as well as ways to store, use, and transmit energy more safely, cleanly, and efficiently. DOE selected Argonne as the site for two new Energy Frontier Research Centers (EFRCs) - the Institute for Atom-Efficient Chemical Transformations and the Center for Electrical Energy Storage - and funded two other EFRCs to which Argonne is a major partner. The award of at least two of the EFRCs can be directly linked to early LDRD-funded efforts. LDRD has historically seeded important programs and facilities at the lab. Two of these facilities, the Advanced Photon Source and the Center for Nanoscale Materials, are now vital contributors to today's LDRD Program. New and enhanced capabilities, many of which relied on LDRD in their early stages, now help the laboratory pursue its evolving strategic goals. LDRD has, since its inception, been an invaluable resource for positioning the Laboratory to anticipate, and thus be prepared to contribute to, the future science and technology needs of DOE and the nation. During times of change, LDRD becomes all the more vital for facilitating the necessary adjustments while maintaining and enhancing the capabilities of our staff and facilities. Although I am new to the role of Laboratory Director, my immediate prior service as Deputy Laboratory Director for Programs afforded me continuous involvement in the LDRD program and its management. Therefore, I can attest that Argonne's program adhered closely to the requirements of DOE Order 413.2b and associated guidelines governing LDRD. Our LDRD program management continually strives to be more efficient. In

  6. Research in the Mont Terri Rock laboratory: Quo vadis?

    Science.gov (United States)

    Bossart, Paul; Thury, Marc

    During the past 10 years, the 12 Mont Terri partner organisations ANDRA, BGR, CRIEPI, ENRESA, FOWG (now SWISSTOPO), GRS, HSK, IRSN, JAEA, NAGRA, OBAYASHI and SCK-CEN have jointly carried out and financed a research programme in the Mont Terri Rock Laboratory. An important strategic question for the Mont Terri project is what type of new experiments should be carried out in the future. This question has been discussed among partner delegates, authorities, scientists, principal investigators and experiment delegates. All experiments at Mont Terri - past, ongoing and future - can be assigned to the following three categories: (1) process and mechanism understanding in undisturbed argillaceous formations, (2) experiments related to excavation- and repository-induced perturbations and (3) experiments related to repository performance during the operational and post-closure phases. In each of these three areas, there are still open questions and hence potential experiments to be carried out in the future. A selection of key issues and questions which have not, or have only partly been addressed so far and in which the project partners, but also the safety authorities and other research organisations may be interested, are presented in the following. The Mont Terri Rock Laboratory is positioned as a generic rock laboratory, where research and development is key: mainly developing methods for site characterisation of argillaceous formations, process understanding and demonstration of safety. Due to geological constraints, there will never be a site specific rock laboratory at Mont Terri. The added value for the 12 partners in terms of future experiments is threefold: (1) the Mont Terri project provides an international scientific platform of high reputation for research on radioactive waste disposal (= state-of-the-art research in argillaceous materials); (2) errors are explicitly allowed (= rock laboratory as a “playground” where experience is often gained through

  7. 2016 Fermilab Laboratory Directed Research & Development Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Wester, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2016-05-25

    Fermilab is executing Laboratory Directed Research and Development (LDRD) as outlined by order DOE O 413.2B in order to enhance and realize the mission of the laboratory in a manner that also supports the laboratory’s strategic objectives and the mission of the Department of Energy. LDRD funds enable scientific creativity, allow for exploration of “high risk, high payoff” research, and allow for the demonstration of new ideas, technical concepts, and devices. LDRD also has an objective of maintaining and enhancing the scientific and technical vitality of Fermilab. LDRD is able to fund employee-initiated proposals that address the current strategic objectives and better position Fermilab for future mission needs. The request for such funds is made in consideration of the investment needs, affordability, and directives from DOE and Congress. Review procedures of the proposals will insure that those proposals which most address the strategic goals of the DOE and the Laboratory or which best position Fermilab for the future will be recommended to the Laboratory Director who has responsibility for approval. The execution of each approved project will be the responsibility of the Principal Investigator, PI, who will follow existing Laboratory guidelines to ensure compliance with safety, environmental, and quality assurance practices. A Laboratory Director-appointed LDRD Coordinator will work with Committees, Laboratory Management, other Fermilab Staff, and the PI’s to oversee the implementation of policies and procedures of LDRD and provide the management and execution of this Annual Program Plan. FY16 represents third fiscal year in which LDRD has existed at Fermilab. The number of preliminary proposals (117) submitted in response to the LDRD Call for Proposals indicates very strong interest of the program within the Fermilab community. The first two Calls have resulted in thirteen active LDRD projects – and it is expected that between five and seven new

  8. Environmental survey at Lucas Heights Research Laboratories, 1993

    Energy Technology Data Exchange (ETDEWEB)

    Hoffmann, E.L.; Looz, T.

    1995-04-01

    Results are presented of the environmental survey conducted in the neighbourhood of the Lucas Heights Research Laboratories during 1993. No activity which could have originated from these laboratories was found in samples collected from possible human food chains. All low-level liquid and gaseous waste discharges were within authorised limits. The maximum possible annual dose to the general public from airborne discharges during this period is estimated to be less than 0.01 mSv, which is one per cent of the dose limit for long term exposure that is recommended by the National Health and Medical Research Council. A list of previous environmental survey reports is attached. 22 refs., 21 tabs., 4 figs.

  9. Research activities on robotics at the Electrotechnical Laboratory

    Science.gov (United States)

    Kakikura, M.

    Various robotics research activities carried out at the Electrotechnical Laboratory in Japan are discussed. The history of robotics research, which has been going on since the late 1960s as a part of artificial-intelligence research is described. Consideration is given to the full-scale robot system called ETL-ROBOT Mk. 1, to the carpenter robot, to the intelligent locomotive-handling robot, to the flexible finger, and to the hand-eye robot. The present aspect of the research in relation to past results is examined and includes the development of new robot systems such as a vision system based on a three-dimensional model, an interactive modeling system, a direct-drive manipulator, a robot vision language, and a language-aided robotic teleoperation system. Research themes planned for the near future include manipulation techniques, sensor techniques, autonomous robot control techniques, advanced teleoperation techniques, and system totalizing techniques.

  10. Impacts: NIST Building and Fire Research Laboratory (technical and societal)

    Science.gov (United States)

    Raufaste, N. J.

    1993-08-01

    The Building and Fire Research Laboratory (BFRL) of the National Institute of Standards and Technology (NIST) is dedicated to the life cycle quality of constructed facilities. The report describes major effects of BFRL's program on building and fire research. Contents of the document include: structural reliability; nondestructive testing of concrete; structural failure investigations; seismic design and construction standards; rehabilitation codes and standards; alternative refrigerants research; HVAC simulation models; thermal insulation; residential equipment energy efficiency; residential plumbing standards; computer image evaluation of building materials; corrosion-protection for reinforcing steel; prediction of the service lives of building materials; quality of construction materials laboratory testing; roofing standards; simulating fires with computers; fire safety evaluation system; fire investigations; soot formation and evolution; cone calorimeter development; smoke detector standards; standard for the flammability of children's sleepwear; smoldering insulation fires; wood heating safety research; in-place testing of concrete; communication protocols for building automation and control systems; computer simulation of the properties of concrete and other porous materials; cigarette-induced furniture fires; carbon monoxide formation in enclosure fires; halon alternative fire extinguishing agents; turbulent mixing research; materials fire research; furniture flammability testing; standard for the cigarette ignition resistance of mattresses; support of navy firefighter trainer program; and using fire to clean up oil spills.

  11. Federal laboratory nondestructive testing research and development applicable to industry

    Energy Technology Data Exchange (ETDEWEB)

    Smith, S.A.; Moore, N.L.

    1987-02-01

    This document presents the results of a survey of nondestructive testing (NDT) and related sensor technology research and development (R and D) at selected federal laboratories. Objective was to identify and characterize NDT activities that could be applied to improving energy efficiency and overall productivity in US manufacturing. Numerous federally supported R and D programs were identified in areas such as acoustic emissions, eddy current, radiography, computer tomography and ultrasonics. A Preliminary Findings Report was sent to industry representatives, which generated considerable interest.

  12. US Army Research Laboratory Directed Energy Internship Program 2014

    Science.gov (United States)

    2015-11-01

    4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to any penalty for failing to comply...photomultiplier tube ( PMT ) with the Fluorolog spectrometer to scan the region. The output of the PMT is sent through the lock-in amplifier before analysis...Nd neodymium NPs nanoparticles NRL US Naval Research Laboratory O oxygen PMT photomultiplier tube SBS stimulated Brillouin scattering SD

  13. Review Article: Research Laboratory Safety and Security | Emeribe ...

    African Journals Online (AJOL)

    No abstract. Journal of Medical Laboratory Science Vol.12(2) 2003: 11 - 17. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · http://dx.doi.org/10.4314/jmls.v12i2.35280 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors ...

  14. Senior Laboratory Animal Technician | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused on the design, generation, characterization and application of genetically engineered and biological animal models of human disease, which are aimed at the development of targeted diagnostics and therapies. LASP contributes to advancing human health, developing new treatments, and improving existing treatments for cancer and other diseases while ensuring safe and humane treatment of animals. Key Roles/Responsibilities The Senior Laboratory Animal Technician will be responsible for: Daily tasks associated with the care, breeding and treatment of research animals for experimental purposes Management of rodent breeding colonies consisting of multiple, genetically complex strains and associated record keeping and database management Colony management procedures including: tail clipping, animal identification, weaning Data entry consistent with complex colony management Collection of routine diagnostic samples Coordinating shipment of live animals and specimens Performing rodent experimental procedures including basic necropsy and blood collection Observation and recording of physical signs of animal health Knowledge of safe working practices using chemical carcinogen and biological hazards Work schedule may include weekend and holiday hours

  15. Dental Biofilm and Laboratory Microbial Culture Models for Cariology Research

    Directory of Open Access Journals (Sweden)

    Ollie Yiru Yu

    2017-06-01

    Full Text Available Dental caries form through a complex interaction over time among dental plaque, fermentable carbohydrate, and host factors (including teeth and saliva. As a key factor, dental plaque or biofilm substantially influence the characteristic of the carious lesions. Laboratory microbial culture models are often used because they provide a controllable and constant environment for cariology research. Moreover, they do not have ethical problems associated with clinical studies. The design of the microbial culture model varies from simple to sophisticated according to the purpose of the investigation. Each model is a compromise between the reality of the oral cavity and the simplification of the model. Researchers, however, can still obtain meaningful and useful results from the models they select. Laboratory microbial culture models can be categorized into a closed system and an open system. Models in the closed system have a finite supply of nutrients, and are also simple and cost-effective. Models in the open system enabled the supply of a fresh culture medium and the removal of metabolites and spent culture liquid simultaneously. They provide better regulation of the biofilm growth rate than the models in the closed system. This review paper gives an overview of the dental plaque biofilm and laboratory microbial culture models used for cariology research.

  16. 2014 Fermilab Laboratory Directoed Research & Development Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Wester, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2016-05-26

    After initiation by the Fermilab Laboratory Director, a team from the senior Laboratory leadership and a Laboratory Directed Research and Development (LDRD) Advisory Committee developed an implementation plan for LDRD at Fermilab for the first time. This implementation was captured in the approved Fermilab 2014 LDRD Program Plan and followed directions and guidance from the Department of Energy (DOE) order, DOE O 413.2B, a “Roles, Responsibilities, and Guidelines, …” document, and examples of best practices at other DOE Office of Science Laboratories. At Fermilab, a FY14 midyear Call for Proposals was issued. A LDRD Selection Committee evaluated those proposals that were received and provided a recommendation to the Laboratory Director who approved seven LDRD projects. This Annual Report focuses on the status of those seven projects and provides an overview of the current status of LDRD at Fermilab. The seven FY14 LDRD approved projects had a date of initiation late in FY14 such that this report reflects approximately six months of effort approximately through January 2015. The progress of these seven projects, the subsequent award of six additional new projects beginning in FY15, and preparations for the issuance of the FY16 Call for Proposals indicates that LDRD is now integrated into the overall annual program at Fermilab. All indications are that LDRD is improving the scientific and technical vitality of the Laboratory and providing new, novel, or cutting edge projects carried out at the forefront of science and technology and aligned with the mission and strategic visions of Fermilab and the Department of Energy.

  17. Laboratory Directed Research and Development Program, FY 1992

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    This report is compiled from annual reports submitted by principal investigators following the close of the 1992 fiscal year. It describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Divisions that report include: Accelerator and Fusion Research, Chemical Sciences, Earth Sciences, Energy and Environment, Engineering, Environment and Safety and Health, Information and Computing Sciences, Life Sciences, Materials Sciences, Nuclear Science, Physics and Structural Biology.

  18. UTRaLab – Urban Traffic Research Laboratory

    OpenAIRE

    Karsten Kozempel; Andreas Luber; Marek Junghans

    2017-01-01

    The Urban Traffic Research Laboratory (UTRaLab) is a research and test track for traffic detection methods and sensors. It is located at the Ernst-Ruska-Ufer, in the southeast of the city of Berlin (Germany). The UTRaLab covers 1 km of a highly-frequented urban road and is connected to a motorway. It is equipped with two gantries with distance of 850 m in between and has several outstations for data collection. The gantries contain many different traffic sensors like inductive loops, cameras,...

  19. Laboratory-directed research and development: FY 1996 progress report

    Energy Technology Data Exchange (ETDEWEB)

    Vigil, J.; Prono, J. [comps.

    1997-05-01

    This report summarizes the FY 1996 goals and accomplishments of Laboratory-Directed Research and Development (LDRD) projects. It gives an overview of the LDRD program, summarizes work done on individual research projects, and provides an index to the projects` principal investigators. Projects are grouped by their LDRD component: Individual Projects, Competency Development, and Program Development. Within each component, they are further divided into nine technical disciplines: (1) materials science, (2) engineering and base technologies, (3) plasmas, fluids, and particle beams, (4) chemistry, (5) mathematics and computational sciences, (6) atomic and molecular physics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) biosciences.

  20. 1996 Laboratory directed research and development annual report

    Energy Technology Data Exchange (ETDEWEB)

    Meyers, C.E.; Harvey, C.L.; Lopez-Andreas, L.M.; Chavez, D.L.; Whiddon, C.P. [comp.

    1997-04-01

    This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 1996. In addition to a programmatic and financial overview, the report includes progress reports from 259 individual R&D projects in seventeen categories. The general areas of research include: engineered processes and materials; computational and information sciences; microelectronics and photonics; engineering sciences; pulsed power; advanced manufacturing technologies; biomedical engineering; energy and environmental science and technology; advanced information technologies; counterproliferation; advanced transportation; national security technology; electronics technologies; idea exploration and exploitation; production; and science at the interfaces - engineering with atoms.

  1. Argonne National Laboratory Annual Report of Laboratory Directed Research and Development program activities FY 2011.

    Energy Technology Data Exchange (ETDEWEB)

    (Office of The Director)

    2012-04-25

    As a national laboratory Argonne concentrates on scientific and technological challenges that can only be addressed through a sustained, interdisciplinary focus at a national scale. Argonne's eight major initiatives, as enumerated in its strategic plan, are Hard X-ray Sciences, Leadership Computing, Materials and Molecular Design and Discovery, Energy Storage, Alternative Energy and Efficiency, Nuclear Energy, Biological and Environmental Systems, and National Security. The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel technical concepts, enhance the Laboratory's research and development (R and D) capabilities, and pursue its strategic goals. projects are selected from proposals for creative and innovative R and D studies that require advance exploration before they are considered to be sufficiently developed to obtain support through normal programmatic channels. Among the aims of the projects supported by the LDRD Program are the following: establishment of engineering proof of principle, assessment of design feasibility for prospective facilities, development of instrumentation or computational methods or systems, and discoveries in fundamental science and exploratory development.

  2. Argonne National Laboratory Annual Report of Laboratory Directed Research and Development program activities FY 2010.

    Energy Technology Data Exchange (ETDEWEB)

    (Office of The Director)

    2012-04-25

    As a national laboratory Argonne concentrates on scientific and technological challenges that can only be addressed through a sustained, interdisciplinary focus at a national scale. Argonne's eight major initiatives, as enumerated in its strategic plan, are Hard X-ray Sciences, Leadership Computing, Materials and Molecular Design and Discovery, Energy Storage, Alternative Energy and Efficiency, Nuclear Energy, Biological and Environmental Systems, and National Security. The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel technical concepts, enhance the Laboratory's research and development (R and D) capabilities, and pursue its strategic goals. projects are selected from proposals for creative and innovative R and D studies that require advance exploration before they are considered to be sufficiently developed to obtain support through normal programmatic channels. Among the aims of the projects supported by the LDRD Program are the following: establishment of engineering proof of principle, assessment of design feasibility for prospective facilities, development of instrumentation or computational methods or systems, and discoveries in fundamental science and exploratory development.

  3. The need for econometric research in laboratory animal operations.

    Science.gov (United States)

    Baker, David G; Kearney, Michael T

    2015-06-01

    The scarcity of research funding can affect animal facilities in various ways. These effects can be evaluated by examining the allocation of financial resources in animal facilities, which can be facilitated by the use of mathematical and statistical methods to analyze economic problems, a discipline known as econometrics. The authors applied econometrics to study whether increasing per diem charges had a negative effect on the number of days of animal care purchased by animal users. They surveyed animal numbers and per diem charges at 20 research institutions and found that demand for large animals decreased as per diem charges increased. The authors discuss some of the challenges involved in their study and encourage research institutions to carry out more robust econometric studies of this and other economic questions facing laboratory animal research.

  4. Publication bias in laboratory animal research: a survey on magnitude, drivers, consequences and potential solutions.

    Directory of Open Access Journals (Sweden)

    Gerben ter Riet

    Full Text Available CONTEXT: Publication bias jeopardizes evidence-based medicine, mainly through biased literature syntheses. Publication bias may also affect laboratory animal research, but evidence is scarce. OBJECTIVES: To assess the opinion of laboratory animal researchers on the magnitude, drivers, consequences and potential solutions for publication bias. And to explore the impact of size of the animals used, seniority of the respondent, working in a for-profit organization and type of research (fundamental, pre-clinical, or both on those opinions. DESIGN: Internet-based survey. SETTING: All animal laboratories in The Netherlands. PARTICIPANTS: Laboratory animal researchers. MAIN OUTCOME MEASURE(S: Median (interquartile ranges strengths of beliefs on 5 and 10-point scales (1: totally unimportant to 5 or 10: extremely important. RESULTS: Overall, 454 researchers participated. They considered publication bias a problem in animal research (7 (5 to 8 and thought that about 50% (32-70 of animal experiments are published. Employees (n = 21 of for-profit organizations estimated that 10% (5 to 50 are published. Lack of statistical significance (4 (4 to 5, technical problems (4 (3 to 4, supervisors (4 (3 to 5 and peer reviewers (4 (3 to 5 were considered important reasons for non-publication (all on 5-point scales. Respondents thought that mandatory publication of study protocols and results, or the reasons why no results were obtained, may increase scientific progress but expected increased bureaucracy. These opinions did not depend on size of the animal used, seniority of the respondent or type of research. CONCLUSIONS: Non-publication of "negative" results appears to be prevalent in laboratory animal research. If statistical significance is indeed a main driver of publication, the collective literature on animal experimentation will be biased. This will impede the performance of valid literature syntheses. Effective, yet efficient systems should be explored to

  5. A 13-week research-based biochemistry laboratory curriculum.

    Science.gov (United States)

    Lefurgy, Scott T; Mundorff, Emily C

    2017-09-01

    Here, we present a 13-week research-based biochemistry laboratory curriculum designed to provide the students with the experience of engaging in original research while introducing foundational biochemistry laboratory techniques. The laboratory experience has been developed around the directed evolution of an enzyme chosen by the instructor, with mutations designed by the students. Ideal enzymes for this curriculum are able to be structurally modeled, solubly expressed, and monitored for activity by UV/Vis spectroscopy, and an example curriculum for haloalkane dehalogenase is given. Unique to this curriculum is a successful implementation of saturation mutagenesis and high-throughput screening of enzyme function, along with bioinformatics analysis, homology modeling, structural analysis, protein expression and purification, polyacrylamide gel electrophoresis, UV/Vis spectroscopy, and enzyme kinetics. Each of these techniques is carried out using a novel student-designed mutant library or enzyme variant unique to the lab team and, importantly, not described previously in the literature. Use of a well-established set of protocols promotes student data quality. Publication may result from the original student-generated hypotheses and data, either from the class as a whole or individual students that continue their independent projects upon course completion. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(5):437-448, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

  6. CSI flight experiment projects of the Naval Research Laboratory

    Science.gov (United States)

    Fisher, Shalom

    1993-02-01

    The Naval Research Laboratory (NRL) is involved in an active program of CSI flight experiments. The first CSI flight experiment of the Naval Research Laboratory, the Low Power Atmospheric Compensation Experiment (LACE) dynamics experiment, has successfully measured vibrations of an orbiting satellite with a ground-based laser radar. The observations, made on January 7, 8 and 10, 1991, represent the first ever measurements of this type. In the tests, a narrowband heterodyne CO2 laser radar, operating at a wavelength of 10.6 microns, detected vibration induced differential-Doppler signatures of the LACE satellite. Power spectral densities of forced oscillations and modal frequencies and damping rates of free-damped vibrations were obtained and compared with finite element structural models of the LACE system. Another manifested flight experiment is the Advanced Controls Technology Experiment (ACTEX) designed to demonstrate active and passive damping with piezo-electric (PZT) sensors and actuators. This experiment was developed under the management of the Air Force Phillips Laboratory with integration of the experiment at NRL. It is to ride as a secondary, or 'piggyback,' experiment on a future Navy satellite.

  7. Overview of photonics research at Lawrence Livermore National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Roeske, F.; Deri, B.; Dijaili, S.; Lee, H.; Lowry, M.; McConaghy, C.; Patterson, F.; Pocha, M.; Strand, T.

    1994-05-01

    Much of Lawrence Livermore National Laboratory`s (LLNL) expertise in photonics was acquired in the execution of the Nuclear Testing mission. As LLNL refocuses its resources into areas that have dual benefit for the nation, their photonics program is beginning to apply these unique capabilities to key national issues involving high-speed communications, while retaining the expertise to apply the technology to defense missions. Much of the exciting work being done at LLNL will have applications in photonics systems and experiments to be used in space. The authors will describe research being conducted in the following areas: high-speed, 50 ohm, phased-matched modulators and their applications to digital links; promising new research on flat-panel displays that will be full color, fast response, very thin, and have a very high resolution; all optical switches that are extremely fast, integrable and do not have the latency problems that exist with current optical switches; semiconductor optical amplifiers that are monolithically integrable, more flexible and less expensive than existing fiber amplifiers; novel, semiconductor waveguide devices; and automated packaging techniques that will lower the cost of photonics components. Much of this research can directly benefit the development of space systems where reliability, size and cost are important considerations. Additional applications in commercial communications and in military system qualifies the photonics research at LLNL as multi-use technology.

  8. Laboratory Directed Research and Development FY2011 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Craig, W; Sketchley, J; Kotta, P

    2012-03-22

    A premier applied-science laboratory, Lawrence Livermore National Laboratory (LLNL) has earned the reputation as a leader in providing science and technology solutions to the most pressing national and global security problems. The LDRD Program, established by Congress at all DOE national laboratories in 1991, is LLNL's most important single resource for fostering excellent science and technology for today's needs and tomorrow's challenges. The LDRD internally directed research and development funding at LLNL enables high-risk, potentially high-payoff projects at the forefront of science and technology. The LDRD Program at Livermore serves to: (1) Support the Laboratory's missions, strategic plan, and foundational science; (2) Maintain the Laboratory's science and technology vitality; (3) Promote recruiting and retention; (4) Pursue collaborations; (5) Generate intellectual property; and (6) Strengthen the U.S. economy. Myriad LDRD projects over the years have made important contributions to every facet of the Laboratory's mission and strategic plan, including its commitment to nuclear, global, and energy and environmental security, as well as cutting-edge science and technology and engineering in high-energy-density matter, high-performance computing and simulation, materials and chemistry at the extremes, information systems, measurements and experimental science, and energy manipulation. A summary of each project was submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to DOE/NNSA and LLNL mission areas, the technical progress achieved in FY11, and a list of publications that resulted from the research. The projects are: (1) Nuclear Threat Reduction; (2) Biosecurity; (3) High-Performance Computing and Simulation; (4) Intelligence; (5) Cybersecurity; (6) Energy Security; (7) Carbon Capture; (8) Material Properties, Theory, and Design; (9) Radiochemistry; (10) High

  9. Using the Human Systems Simulation Laboratory at Idaho National Laboratory for Safety Focused Research

    Energy Technology Data Exchange (ETDEWEB)

    Joe, Jeffrey .C; Boring, Ronald L.

    2016-07-01

    Under the United States (U.S.) Department of Energy (DOE) Light Water Reactor Sustainability (LWRS) program, researchers at Idaho National Laboratory (INL) have been using the Human Systems Simulation Laboratory (HSSL) to conduct critical safety focused Human Factors research and development (R&D) for the nuclear industry. The LWRS program has the overall objective to develop the scientific basis to extend existing nuclear power plant (NPP) operating life beyond the current 60-year licensing period and to ensure their long-term reliability, productivity, safety, and security. One focus area for LWRS is the NPP main control room (MCR), because many of the instrumentation and control (I&C) system technologies installed in the MCR, while highly reliable and safe, are now difficult to replace and are therefore limiting the operating life of the NPP. This paper describes how INL researchers use the HSSL to conduct Human Factors R&D on modernizing or upgrading these I&C systems in a step-wise manner, and how the HSSL has addressed a significant gap in how to upgrade systems and technologies that are built to last, and therefore require careful integration of analog and new advanced digital technologies.

  10. A Survey on Faculty Perspectives on the Transition to a Biochemistry Course-Based Undergraduate Research Experience Laboratory

    Science.gov (United States)

    Craig, Paul A.

    It will always remain a goal of an undergraduate biochemistry laboratory course to engage students hands-on in a wide range of biochemistry laboratory experiences. In 2006, our research group initiated a project for "in silico" prediction of enzyme function based only on the 3D coordinates of the more than 3800 proteins "of unknown…

  11. Searching for the Haplorrhine Heterotherm: Field and Laboratory Data of Free-Ranging Tarsiers

    Directory of Open Access Journals (Sweden)

    Shaun Welman

    2017-09-01

    Full Text Available The observation of heterothermy in a single suborder (Strepsirrhini only within the primates is puzzling. Given that the placental-mammal ancestor was likely a heterotherm, we explored the potential for heterothermy in a primate closely related to the Strepsirrhini. Based upon phylogeny, body size and habitat stability since the Late Eocene, we selected western tarsiers (Cephalopachus bancanus from the island of Borneo. Being the sister clade to Strepsirrhini and basal in Haplorrhini (monkeys and apes, we hypothesized that C. bancanus might have retained the heterothermic capacity observed in several small strepsirrhines. We measured resting metabolic rate, subcutaneous temperature, evaporative water loss and the percentage of heat dissipated through evaporation, at ambient temperatures between 22 and 35°C in fresh-caught wild animals (126.1 ± 2.4 g. We also measured core body temperatures in free-ranging animals. The thermoneutral zone was 25–30°C and the basal metabolic rate was 3.52 ± 0.06 W.kg−1 (0.65 ± 0.01 ml O2.g−1.h−1. There was no evidence of adaptive heterothermy in either the laboratory data or the free-ranging data. Instead, animals appeared to be cold sensitive (Tb ~ 31°C at the lowest temperatures. We discuss possible reasons for the apparent lack of heterothermy in tarsiers, and identify putative heterotherms within Platyrrhini. We also document our concern for the vulnerability of C. bancanus to future temperature increases associated with global warming.

  12. Lawrence Livermore National Laboratory FY 2016 Laboratory Directed Research and Development Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Al-Ayat, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Gard, E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sketchley, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Watkins, L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-10-16

    The LDRD annual report for FY2016 consists of two parts: The Overview. This section contains a broad description of the LDRD Program, highlights of recent accomplishments and awards, Program statistics, and the LDRD portfolio-management processes. Project Reports. Project reports are submitted by all principal investigators at the end of the fiscal year. The length and depth of the report depends on the project’s lifecycle. For projects that will be continuing the following year, the principal investigator submits a continuing project report, which is a brief update containing descriptions of the goals, scope, motivation, relevance (to DOE/NNSA and Livermore mission areas), and technical progress achieved in FY16, as well as a list of selected publications and presentations that resulted from the research. For projects that concluded in FY16, a more detailed final report is provided that is technical in nature and includes the background, objectives, scientific approach, accomplishments, and impacts on the Laboratory missions, as well as a list of publications and presentations that resulted from the research. Project reports are listed under their research topics and organized by year and type, such as exploratory research (ER), feasibility study (FS), laboratory-wide competition (LW), and strategic initiative (SI). Each project is assigned a unique tracking code, an identifier that consists of three elements. The first is the fiscal year in which the project began, the second represents the project type, and the third identifies the serial number of the project for that fiscal year. For example, 16-ERD-100 means the project is an exploratory research project that began in FY16. The three-digit number (100) represents the serial number for the project.

  13. Tritium research laboratory cleanup and transition project final report

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, A.J.

    1997-02-01

    This Tritium Research Laboratory Cleanup and Transition Project Final Report provides a high-level summary of this project`s multidimensional accomplishments. Throughout this report references are provided for in-depth information concerning the various topical areas. Project related records also offer solutions to many of the technical and or administrative challenges that such a cleanup effort requires. These documents and the experience obtained during this effort are valuable resources to the DOE, which has more than 1200 other process contaminated facilities awaiting cleanup and reapplication or demolition.

  14. Secondary Aluminum Melting Research in a Laboratory Scale Reverberatory Furnace

    Energy Technology Data Exchange (ETDEWEB)

    Clark, J.A., III

    2003-01-01

    The Albany Research Center (ARC), U.S. Department of Energy, has developed a 175-pound capacity, natural gas, direct-fired reverberatory furnace. The high temperature reactions present during the aluminum remelt process are being investigated. Preventing dross formation has been the key aim to date. Reducing losses to dross by 25-50% will potentially lead to an annual energy savings of over 75 trillion BTU's by the year 2020. Schematics and operation characteristics of the ARC Laboratory Scale Reverberatory Furnace (LSRF) will be presented. Potential gas-solid, gas-liquid, and liquid-solid interactions between the hot combustion gases, aluminum, and refractories will be discussed.

  15. 1997 Laboratory directed research and development. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    Meyers, C.E.; Harvey, C.L.; Chavez, D.L.; Whiddon, C.P. [comps.

    1997-12-31

    This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 1997. In addition to a programmatic and financial overview, the report includes progress reports from 218 individual R&D projects in eleven categories. Theses reports are grouped into the following areas: materials science and technology; computer sciences; electronics and photonics; phenomenological modeling and engineering simulation; manufacturing science and technology; life-cycle systems engineering; information systems; precision sensing and analysis; environmental sciences; risk and reliability; national grand challenges; focused technologies; and reserve.

  16. PDC (polycrystalline diamond compact) bit research at Sandia National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Finger, J.T.; Glowka, D.A.

    1989-06-01

    From the beginning of the geothermal development program, Sandia has performed and supported research into polycrystalline diamond compact (PDC) bits. These bits are attractive because they are intrinsically efficient in their cutting action (shearing, rather than crushing) and they have no moving parts (eliminating the problems of high-temperature lubricants, bearings, and seals.) This report is a summary description of the analytical and experimental work done by Sandia and our contractors. It describes analysis and laboratory tests of individual cutters and complete bits, as well as full-scale field tests of prototype and commercial bits. The report includes a bibliography of documents giving more detailed information on these topics. 26 refs.

  17. Laboratory directed research and development annual report 2004.

    Energy Technology Data Exchange (ETDEWEB)

    2005-03-01

    This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 2004. In addition to a programmatic and financial overview, the report includes progress reports from 352 individual R and D projects in 15 categories. The 15 categories are: (1) Advanced Concepts; (2) Advanced Manufacturing; (3) Biotechnology; (4) Chemical and Earth Sciences; (5) Computational and Information Sciences; (6) Differentiating Technologies; (7) Electronics and Photonics; (8) Emerging Threats; (9) Energy and Critical Infrastructures; (10) Engineering Sciences; (11) Grand Challenges; (12) Materials Science and Technology; (13) Nonproliferation and Materials Control; (14) Pulsed Power and High Energy Density Sciences; and (15) Corporate Objectives.

  18. A design guide for energy-efficient research laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Wishner, N.; Chen, A.; Cook, L. [eds.; Bell, G.C.; Mills, E.; Sartor, D.; Avery, D.; Siminovitch, M.; Piette, M.A.

    1996-09-24

    This document--A Design Guide for Energy-Efficient Research Laboratories--provides a detailed and holistic framework to assist designers and energy managers in identifying and applying advanced energy-efficiency features in laboratory-type environments. The Guide fills an important void in the general literature and compliments existing in-depth technical manuals. Considerable information is available pertaining to overall laboratory design issues, but no single document focuses comprehensively on energy issues in these highly specialized environments. Furthermore, practitioners may utilize many antiquated rules of thumb, which often inadvertently cause energy inefficiency. The Guide helps its user to: introduce energy decision-making into the earliest phases of the design process, access the literature of pertinent issues, and become aware of debates and issues on related topics. The Guide does focus on individual technologies, as well as control systems, and important operational factors such as building commissioning. However, most importantly, the Guide is intended to foster a systems perspective (e.g. right sizing) and to present current leading-edge, energy-efficient design practices and principles.

  19. Status of Avian Research at the National Renewable Energy Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Sinclair, K.

    2001-09-18

    As the use of wind energy expands across the United States, concerns about the impacts of commercial wind farms on bird and bat populations are frequently raised. Two primary areas of concern are (1) possible litigation resulting from the killing of even one bird if it is protected by the Migratory Bird Treaty Act, the Endangered Species Act, or both; and (2) the effect of avian mortality on bird populations. To properly address these concerns, the U.S. Department of Energy's National Renewable Energy Laboratory (NREL) supports scientifically based avian/wind power interaction research. In this paper I describe NREL's field-based research projects and summarize the status of the research. I also summarize NREL's other research activities, including lab-based vision research to increase the visibility of moving turbine blades and avian acoustic research, as well as our collaborative efforts with the National Wind Coordinating Committee's Avian Subcommittee.

  20. Establishment of a clean chemistry laboratory at JAERI. Clean laboratory for environmental analysis and research (CLEAR)

    Energy Technology Data Exchange (ETDEWEB)

    Hanzawa, Yukiko; Magara, Masaaki; Watanabe, Kazuo [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment] [and others

    2003-02-01

    The JAERI has established a facility with a cleanroom: the Clean Laboratory for Environmental Analysis and Research (CLEAR). This report is an overview of the design, construction and performance evaluation of the CLEAR in the initial stage of the laboratory operation in June 2001. The CLEAR is a facility to be used for analyses of ultra trace amounts of nuclear materials in environmental samples for the safeguards, for the CTBT verification and for researches on environmental sciences. One of the special features of the CLEAR is that it meets double requirements of a cleanroom and for handling of nuclear materials. As another feature of the CLEAR, much attention was paid to the construction materials of the cleanroom for trace analysis of metal elements using considerable amounts of corrosive acids. The air conditioning and purification system, specially designed experimental equipment to provide clean work surfaces, utilities and safety systems are also demonstrated. The potential contamination from the completed cleanroom atmosphere during the analytical procedure was evaluated. It can be concluded that the CLEAR has provided a suitable condition for reliable analysis of ultra trace amounts of nuclear materials and other heavy elements in environmental samples. (author)

  1. A Virtual Laboratory for Aviation and Airspace Prognostics Research

    Science.gov (United States)

    Kulkarni, Chetan; Gorospe, George; Teubert, Christ; Quach, Cuong C.; Hogge, Edward; Darafsheh, Kaveh

    2017-01-01

    Integration of Unmanned Aerial Vehicles (UAVs), autonomy, spacecraft, and other aviation technologies, in the airspace is becoming more and more complicated, and will continue to do so in the future. Inclusion of new technology and complexity into the airspace increases the importance and difficulty of safety assurance. Additionally, testing new technologies on complex aviation systems and systems of systems can be challenging, expensive, and at times unsafe when implementing real life scenarios. The application of prognostics to aviation and airspace management may produce new tools and insight into these problems. Prognostic methodology provides an estimate of the health and risks of a component, vehicle, or airspace and knowledge of how that will change over time. That measure is especially useful in safety determination, mission planning, and maintenance scheduling. In our research, we develop a live, distributed, hardware- in-the-loop Prognostics Virtual Laboratory testbed for aviation and airspace prognostics. The developed testbed will be used to validate prediction algorithms for the real-time safety monitoring of the National Airspace System (NAS) and the prediction of unsafe events. In our earlier work1 we discussed the initial Prognostics Virtual Laboratory testbed development work and related results for milestones 1 & 2. This paper describes the design, development, and testing of the integrated tested which are part of milestone 3, along with our next steps for validation of this work. Through a framework consisting of software/hardware modules and associated interface clients, the distributed testbed enables safe, accurate, and inexpensive experimentation and research into airspace and vehicle prognosis that would not have been possible otherwise. The testbed modules can be used cohesively to construct complex and relevant airspace scenarios for research. Four modules are key to this research: the virtual aircraft module which uses the X

  2. UTRaLab – Urban Traffic Research Laboratory

    Directory of Open Access Journals (Sweden)

    Karsten Kozempel

    2017-08-01

    Full Text Available The Urban Traffic Research Laboratory (UTRaLab is a research and test track for traffic detection methods and sensors. It is located at the Ernst-Ruska-Ufer, in the southeast of the city of Berlin (Germany. The UTRaLab covers 1 km of a highly-frequented urban road and is connected to a motorway. It is equipped with two gantries with distance of 850 m in between and has several outstations for data collection. The gantries contain many different traffic sensors like inductive loops, cameras, lasers or wireless sensors for traffic data acquisition. Additionally a weather station records environmental data. The UTRaLab’s main purposes are the data collection of traffic data on the one hand and testing newly developed sensors on the other hand.

  3. Laboratory Directed Research and Development 1998 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Pam Hughes; Sheila Bennett eds.

    1999-07-14

    The Laboratory's Directed Research and Development (LDRD) program encourages the advancement of science and the development of major new technical capabilities from which future research and development will grow. Through LDRD funding, Pacific Northwest continually replenishes its inventory of ideas that have the potential to address major national needs. The LDRD program has enabled the Laboratory to bring to bear its scientific and technical capabilities on all of DOE's missions, particularly in the arena of environmental problems. Many of the concepts related to environmental cleanup originally developed with LDRD funds are now receiving programmatic support from DOE, LDRD-funded work in atmospheric sciences is now being applied to DOE's Atmospheric Radiation Measurement Program. We also have used concepts initially explored through LDRD to develop several winning proposals in the Environmental Management Science Program. The success of our LDRD program is founded on good management practices that ensure funding is allocated and projects are conducted in compliance with DOE requirements. We thoroughly evaluate the LDRD proposals based on their scientific and technical merit, as well as their relevance to DOE's programmatic needs. After a proposal is funded, we assess progress annually using external peer reviews. This year, as in years past, the LDRD program has once again proven to be the major enabling vehicle for our staff to formulate new ideas, advance scientific capability, and develop potential applications for DOE's most significant challenges.

  4. Behavioral Economic Laboratory Research in Tobacco Regulatory Science

    Science.gov (United States)

    Tidey, Jennifer W.; Cassidy, Rachel N.; Miller, Mollie E.; Smith, Tracy T.

    2017-01-01

    Objectives Research that can provide a scientific foundation for the United States Food and Drug Administration (FDA) tobacco policy decisions is needed to inform tobacco regulatory policy. One factor that affects the impact of a tobacco product on public health is its intensity of use, which is determined, in part, by its abuse liability or reinforcing efficacy. Behavioral economic tasks have considerable utility for assessing the reinforcing efficacy of current and emerging tobacco products. Methods This paper provides a narrative review of several behavioral economic laboratory tasks and identifies important applications to tobacco regulatory science. Results Behavioral economic laboratory assessments, including operant self-administration, choice tasks and purchase tasks, can be used generate behavioral economic data on the effect of price and other constraints on tobacco product consumption. These tasks could provide an expedited simulation of the effects of various tobacco control policies across populations of interest to the FDA. Conclusions Tobacco regulatory research questions that can be addressed with behavioral economic tasks include assessments of the impact of product characteristics on product demand, assessments of the abuse liability of novel and potential modified risk tobacco products (MRTPs), and assessments of the impact of conventional and novel products in vulnerable populations. PMID:28580378

  5. Laboratory Directed Research and Development Program FY2011

    Energy Technology Data Exchange (ETDEWEB)

    none, none

    2012-04-27

    Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2011 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). Going forward in FY 2012, the LDRD program also supports the Goals codified in the new DOE Strategic Plan of May, 2011. The LDRD program also supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under consideration and review by the Office of Science Program Offices, such as LDRD projects germane to new research facility concepts and new fundamental science directions. Brief summares of projects and accomplishments for the period for each division are included.

  6. Apoptosis as the focus of an authentic research experience in a cell physiology laboratory.

    Science.gov (United States)

    Byrd, Shere K

    2016-06-01

    Curriculum-embedded independent research is a high-impact teaching practice that has been shown to increase student engagement and learning. This article describes a multiweek laboratory project for an upper-division undergraduate cell physiology laboratory using apoptosis via the mitochondrial pathway as the overarching theme. Students did literature research on apoptotic agents that acted via the mitochondrial pathway. Compounds ranged from natural products such as curcumin to synthetic compounds such as etoposide. Groups of two to three students planned a series of experiments using one of three cultured cell lines that required them to 1) learn to culture cells; 2) determine treatment conditions, including apoptotic agent solubility and concentration ranges that had been reported in the literature; 3) choose two methods to validate/quantify apoptotic capacity of the reagent; and 4) attempt to "rescue" cells from undergoing apoptosis using one of several available compounds/methods. In essence, given some reagent and equipment constraints, students designed an independent experiment to highlight the effects of different apoptotic agents on cells in culture. Students presented their experimental designs as in a laboratory group meeting and their final findings as a classroom "symposium." This exercise can be adapted to many different types of laboratories with greater or lesser equipment and instrumentation constraints, incorporates several core cell physiology methods, and encourages key experimental design and critical thinking components of independent research. Copyright © 2016 The American Physiological Society.

  7. Comprehensive reference ranges for hematology and clinical chemistry laboratory parameters derived from normal Nigerian adults.

    Science.gov (United States)

    Miri-Dashe, Timzing; Osawe, Sophia; Tokdung, Monday; Daniel, Monday Tokdung Nenbammun; Daniel, Nenbammun; Choji, Rahila Pam; Mamman, Ille; Deme, Kurt; Damulak, Dapus; Abimiku, Alash'le

    2014-01-01

    Interpretation of laboratory test results with appropriate diagnostic accuracy requires reference or cutoff values. This study is a comprehensive determination of reference values for hematology and clinical chemistry in apparently healthy voluntary non-remunerated blood donors and pregnant women. Consented clients were clinically screened and counseled before testing for HIV, Hepatitis B, Hepatitis C and Syphilis. Standard national blood donors' questionnaire was administered to consented blood donors. Blood from qualified volunteers was used for measurement of complete hematology and chemistry parameters. Blood samples were analyzed from a total of 383 participants, 124 (32.4%) males, 125 (32.6%) non-pregnant females and 134 pregnant females (35.2%) with a mean age of 31 years. Our results showed that the red blood cells count (RBC), Hemoglobin (HB) and Hematocrit (HCT) had significant gender difference (p = 0.000) but not for total white blood count (p>0.05) which was only significantly higher in pregnant verses non-pregnant women (p = 0.000). Hemoglobin and Hematocrit values were lower in pregnancy (P = 0.000). Platelets were significantly higher in females than men (p = 0.001) but lower in pregnant women (p =  .001) with marked difference in gestational period. For clinical chemistry parameters, there was no significant difference for sodium, potassium and chloride (p>0.05) but gender difference exists for Bicarbonate (HCO3), Urea nitrogen, Creatinine as well as the lipids (p0.05). Hematological and Clinical Chemistry reference ranges established in this study showed significant gender differences. Pregnant women also differed from non-pregnant females and during pregnancy. This is the first of such comprehensive study to establish reference values among adult Nigerians and difference observed underscore the need to establish reference values for different populations.

  8. Comprehensive reference ranges for hematology and clinical chemistry laboratory parameters derived from normal Nigerian adults.

    Directory of Open Access Journals (Sweden)

    Timzing Miri-Dashe

    Full Text Available BACKGROUND: Interpretation of laboratory test results with appropriate diagnostic accuracy requires reference or cutoff values. This study is a comprehensive determination of reference values for hematology and clinical chemistry in apparently healthy voluntary non-remunerated blood donors and pregnant women. METHODS AND FINDINGS: Consented clients were clinically screened and counseled before testing for HIV, Hepatitis B, Hepatitis C and Syphilis. Standard national blood donors' questionnaire was administered to consented blood donors. Blood from qualified volunteers was used for measurement of complete hematology and chemistry parameters. Blood samples were analyzed from a total of 383 participants, 124 (32.4% males, 125 (32.6% non-pregnant females and 134 pregnant females (35.2% with a mean age of 31 years. Our results showed that the red blood cells count (RBC, Hemoglobin (HB and Hematocrit (HCT had significant gender difference (p = 0.000 but not for total white blood count (p>0.05 which was only significantly higher in pregnant verses non-pregnant women (p = 0.000. Hemoglobin and Hematocrit values were lower in pregnancy (P = 0.000. Platelets were significantly higher in females than men (p = 0.001 but lower in pregnant women (p =  .001 with marked difference in gestational period. For clinical chemistry parameters, there was no significant difference for sodium, potassium and chloride (p>0.05 but gender difference exists for Bicarbonate (HCO3, Urea nitrogen, Creatinine as well as the lipids (p0.05. CONCLUSIONS: Hematological and Clinical Chemistry reference ranges established in this study showed significant gender differences. Pregnant women also differed from non-pregnant females and during pregnancy. This is the first of such comprehensive study to establish reference values among adult Nigerians and difference observed underscore the need to establish reference values for different populations.

  9. Laboratory Column Evaluation of High Explosives Attenuation in Grenade Range Soils.

    Science.gov (United States)

    Won, Jongho; Borden, Robert C

    2017-09-01

    High explosives (HEs) deposited on military ranges can leach through the soil and contaminate groundwater. We examined the transport and fate of HEs in laboratory columns containing soils from two hand grenade bays (Bays C and T) and the impact of organic amendments on biodegradation. Soil characteristics were similar; however, Bay C had somewhat higher clay and organic C. Experimental treatments included addition of crude glycerin and lignosulfonate, and parallel control columns. Experimental results showed extensive 2,4,6-trinitrotoluene (TNT) degradation with minimal leaching, consistent with prior batch microcosm results. Amendment addition enhanced TNT degradation in both Bays C and T compared with controls. Although hexahydro-1,3,5-trinitro-1,3,5-triazine (Royal Demolition Explosive, or RDX) did not biodegrade in prior aerobic batch microcosms, 64 to 77% of RDX biodegraded in untreated soil columns with O present in the mobile soil gas. The RDX biodegradation was likely associated with short-term anoxic conditions or anoxic micro-niches. In nearly saturated Bay C columns, RDX removal increased to >92%. Amendment addition to unsaturated Bay T columns increased RDX removal to >86%. In one column, the soil remained anoxic (O < 5% by volume) for about a year after amendment addition, significantly reducing RDX leaching. Nitroso degradation products were produced equivalent to 9 to 39% of the RDX degraded, with most retained in the soil (9-37%) and 0 to 3% in the effluent. These results demonstrate that RDX biodegradation can occur in soils with measurable O, and that amendment addition can reduce RDX leaching by stimulating anaerobic biodegradation. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  10. Laboratory directed research and development annual report 2003.

    Energy Technology Data Exchange (ETDEWEB)

    2004-03-01

    Science historian James Burke is well known for his stories about how technological innovations are intertwined and embedded in the culture of the time, for example, how the steam engine led to safety matches, imitation diamonds, and the landing on the moon.1 A lesson commonly drawn from his stories is that the path of science and technology (S&T) is nonlinear and unpredictable. Viewed another way, the lesson is that the solution to one problem can lead to solutions to other problems that are not obviously linked in advance, i.e., there is a ripple effect. The motto for Sandia's approach to research and development (R&D) is 'Science with the mission in mind.' In our view, our missions contain the problems that inspire our R&D, and the resulting solutions almost always have multiple benefits. As discussed below, Sandia's Laboratory Directed Research and Development (LDRD) Program is structured to bring problems relevant to our missions to the attention of researchers. LDRD projects are then selected on the basis of their programmatic merit as well as their technical merit. Considerable effort is made to communicate between investment areas to create the ripple effect. In recent years, attention to the ripple effect and to the performance of the LDRD Program, in general, has increased. Inside Sandia, as it is the sole source of discretionary research funding, LDRD funding is recognized as being the most precious of research dollars. Hence, there is great interest in maximizing its impact, especially through the ripple effect. Outside Sandia, there is increased scrutiny of the program's performance to be sure that it is not a 'sandbox' in which researchers play without relevance to national security needs. Let us therefore address the performance of the LDRD Program in fiscal year 2003 and then show how it is designed to maximize impact.

  11. Idaho National Laboratory Directed Research and Development FY-2009

    Energy Technology Data Exchange (ETDEWEB)

    2010-03-01

    The FY 2009 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support the future DOE missions and national research priorities. LDRD is essential to the INL - it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enhances technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development. Established by Congress in 1991, LDRD proves its benefit each year through new programs, intellectual property, patents, copyrights, publications, national and international awards, and new hires from the universities and industry, which helps refresh the scientific and engineering workforce. The benefits of INL's LDRD research are many as shown in the tables below. Last year, 91 faculty members from various universities contributed to LDRD research, along with 7 post docs and 64 students. Of the total invention disclosures submitted in FY 2009, 7 are attributable to LDRD research. Sixty three refereed journal articles were accepted or published, and 93 invited presentations were attributable to LDRD research conducted in FY 2009. The LDRD Program is administered in accordance with requirements set in DOE Order 413.2B, accompanying contractor requirements, and other DOE and federal requirements invoked through the INL contract. The LDRD Program is implemented in accordance with the annual INL LDRD Program Plan, which is approved by the DOE, Nuclear Energy Program Secretarial Office. This plan outlines the method the laboratory uses to develop its research portfolio, including peer and management reviews, and the use of other INL management systems to ensure quality, financial, safety, security and environmental requirements and risks are

  12. Neutron Imaging at the Oak Ridge National Laboratory: Application to Biological Research

    Energy Technology Data Exchange (ETDEWEB)

    Bilheux, Hassina Z [ORNL; Cekanova, Maria [University of Tennessee, Knoxville (UTK); Bilheux, Jean-Christophe [ORNL; Bailey, William Barton [ORNL; Keener, Wylie S [ORNL; Davis, Larry E [ORNL; Herwig, Kenneth W [ORNL

    2014-01-01

    The Oak Ridge National Laboratory Neutron Sciences Directorate (NScD) has recently installed a neutron imaging beamline at the High Flux Isotope Reactor (HFIR) cold guide hall. The CG-1D beamline supports a broad range of user research spanning from engineering to material research, energy storage, additive manufacturing, vehicle technologies, archaeology, biology, and plant physiology. The beamline performance (spatial resolution, field of view, etc.) and its utilization for biological research are presented. The NScD is also considering a proposal to build the VENUS imaging beamline (beam port 10) at the Spallation Neutron Source (SNS). Unlike CG-1D which provides cold neutrons, VENUS will offer a broad range of neutron wavelengths, from epithermal to cold, and enhanced contrast mechanisms. This new capability will also enable the imaging of thicker biological samples than is currently available at CG-1D. A brief overview of the VENUS capability for biological research is discussed.

  13. Synchrotron radiation applications in medical research at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Thomlinson, W.

    1997-08-01

    In the relatively short time that synchrotrons have been available to the scientific community, their characteristic beams of UV and X-ray radiation have been applied to virtually all areas of medical science which use ionizing radiation. The ability to tune intense monochromatic beams over wide energy ranges clearly differentiates these sources from standard clinical and research tools. The tunable spectrum, high intrinsic collimation of the beams, polarization and intensity of the beams make possible in-vitro and in-vivo research and therapeutic programs not otherwise possible. From the beginning of research operation at the National Synchrotron Light Source (NSLS), many programs have been carrying out basic biomedical research. At first, the research was limited to in-vitro programs such as the x-ray microscope, circular dichroism, XAFS, protein crystallography, micro-tomography and fluorescence analysis. Later, as the coronary angiography program made plans to move its experimental phase from SSRL to the NSLS, it became clear that other in-vivo projects could also be carried out at the synchrotron. The development of SMERF (Synchrotron Medical Research Facility) on beamline X17 became the home not only for angiography but also for the MECT (Multiple Energy Computed Tomography) project for cerebral and vascular imaging. The high energy spectrum on X17 is necessary for the MRT (Microplanar Radiation Therapy) experiments. Experience with these programs and the existence of the Medical Programs Group at the NSLS led to the development of a program in synchrotron based mammography. A recent adaptation of the angiography hardware has made it possible to image human lungs (bronchography). Fig. 1 schematically depicts the broad range of active programs at the NSLS.

  14. Learning about Manatees: A Collaborative Program between New College of Florida and Mote Marine Laboratory to Conduct Laboratory Research for Manatee Conservation

    OpenAIRE

    Bauer, Gordon B.; Colbert, Debborah E.; Gaspard III, Joseph C.

    2010-01-01

    Research with captive manatees initiated as part of a New College of Florida class project at MoteMarine Laboratory has yielded a wide range of research with substantive implications formanagement and conservation. Our training program directly supported investigations of bloodchemistry, immune function, stress-related physiology, respiration, thermoregulation, and behavioralecology. Our investigations of sensory processes included studies of visual acuity, color vision,passive and active tou...

  15. Brain Cancer in Workers Employed at a Laboratory Research Facility.

    Directory of Open Access Journals (Sweden)

    James J Collins

    Full Text Available An earlier study of research facility workers found more brain cancer deaths than expected, but no workplace exposures were implicated.Adding four additional years of vital-status follow-up, we reassessed the risk of death from brain cancer in the same workforce, including 5,284 workers employed between 1963, when the facility opened, and 2007. We compared the work histories of the brain cancer decedents in relationship to when they died and their ages at death.As in most other studies of laboratory and research workers, we found low rates of total mortality, total cancers, accidents, suicides, and chronic conditions such as heart disease and diabetes. We found no new brain cancer deaths in the four years of additional follow-up. Our best estimate of the brain cancer standardized mortality ratio (SMR was 1.32 (95% confidence interval [95% CI] 0.66-2.37, but the SMR might have been as high as 1.69. Deaths from benign brain tumors and other non-malignant diseases of the nervous system were at or below expected levels.With the addition of four more years of follow-up and in the absence of any new brain cancers, the updated estimate of the risk of brain cancer death is smaller than in the original study. There was no consistent pattern among the work histories of decedents that indicated a common causative exposure.

  16. NATO Advanced Research Workshop on Smart Materials for Ranging Systems

    CERN Document Server

    Franse, Jaap; Sirenko, Valentyna

    2006-01-01

    The problem of determining the location of an object (usually called ranging) attracts at present much attention in different areas of applications, among them in ecological and safety devices. Electromagnetic waves along with sound waves are widely used for these purposes. Different aspects of materials with specific magnetic, electric and elastic properties are considered in view of potential application in the design and manufacturing of smart materials. Progress is reported in the fabrication and understanding of in-situ formation and characterization of solid state structures with specified properties. Attention is paid to the observation and study of the mobility of magnetic structures and of the kinetics of magnetic ordering transitions. Looking from a different perspective, one of the outcomes of the ARW is the emphasis on the important role that collective phenomena (like spin waves in systems with a magnetically ordered ground state, or critical currents in superconductors) could play at the design ...

  17. Using a Mobile Laboratory to Study Mental Health, Addictions and Violence: A Research Plan

    Directory of Open Access Journals (Sweden)

    Samantha Wells

    2011-01-01

    Full Text Available This paper describes an innovative new research program, Researching Health in Ontario Communities (RHOC, designed to improve understanding, treatment and prevention of co-occurring mental health, addictions, and violence problems. RHOC brings together a multi-disciplinary team of investigators to implement an integrated series of research studies (including pilot studies and full studies. The project involves use a mobile research laboratory to collect a wide range of biological, behavioral and social data in diverse communities across Ontario, Canada, including remote and rural communities, areas experiencing poverty and social disorganization, urban areas, and Aboriginal communities. This paper describes the project background and research plan as well as the anticipated contributions of the project to participating Ontario communities and to broader scientific knowledge.

  18. National Research Council Research Associateships Program with Methane Hydrates Fellowships Program/National Energy Technology Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Basques, Eric O. [National Academy of Sciences, Washington, DC (United States)

    2014-03-20

    This report summarizes work carried out over the period from July 5, 2005-January 31, 2014. The work was carried out by the National Research Council Research Associateships Program of the National Academies, under the US Department of Energy's National Energy Technology Laboratory (NETL) program. This Technical Report consists of a description of activity from 2005 through 2014, broken out within yearly timeframes, for NRC/NETL Associateships researchers at NETL laboratories which includes individual tenure reports from Associates over this time period. The report also includes individual tenure reports from associates over this time period. The report also includes descriptions of program promotion efforts, a breakdown of the review competitions, awards offered, and Associate's activities during their tenure.

  19. Amphibians as animal models for laboratory research in physiology.

    Science.gov (United States)

    Burggren, Warren W; Warburton, Stephen

    2007-01-01

    The concept of animal models is well honored, and amphibians have played a prominent part in the success of using key species to discover new information about all animals. As animal models, amphibians offer several advantages that include a well-understood basic physiology, a taxonomic diversity well suited to comparative studies, tolerance to temperature and oxygen variation, and a greater similarity to humans than many other currently popular animal models. Amphibians now account for approximately 1/4 to 1/3 of lower vertebrate and invertebrate research, and this proportion is especially true in physiological research, as evident from the high profile of amphibians as animal models in Nobel Prize research. Currently, amphibians play prominent roles in research in the physiology of musculoskeletal, cardiovascular, renal, respiratory, reproductive, and sensory systems. Amphibians are also used extensively in physiological studies aimed at generating new insights in evolutionary biology, especially in the investigation of the evolution of air breathing and terrestriality. Environmental physiology also utilizes amphibians, ranging from studies of cryoprotectants for tissue preservation to physiological reactions to hypergravity and space exploration. Amphibians are also playing a key role in studies of environmental endocrine disruptors that are having disproportionately large effects on amphibian populations and where specific species can serve as sentinel species for environmental pollution. Finally, amphibian genera such as Xenopus, a genus relatively well understood metabolically and physiologically, will continue to contribute increasingly in this new era of systems biology and "X-omics."

  20. Dryden Aeronautical Test Range

    Data.gov (United States)

    Federal Laboratory Consortium — Recently redesignated to honor Dr. Hugh L. Dryden, NASA's Dryden Aeronautical Test Range (DATR) supports aerospace flight research and technology integration, space...

  1. The hot cell laboratories for material investigations of the Institute for Safety Research

    Energy Technology Data Exchange (ETDEWEB)

    Viehrig, H.W.

    1998-10-01

    Special facilities for handling and testing of irradiated specimens are necessary, to perform the investigation of activated material. The Institute for Safety Research has two hot cell laboratories: - the preparation laboratory and - the materials testing laboratory. This report is intended to give an overview of the available facilities and developed techniques in the laboratories. (orig.)

  2. Pacific Northwest Laboratory annual report for 1992 to the DOE Office of Energy Research. Part 3, Atmospheric and climate research

    Energy Technology Data Exchange (ETDEWEB)

    Schrempf, R.E. [ed.

    1993-04-01

    Within the US Department of Energy`s (DOE`s) Office of Health and Environmental Research (OHER), the atmospheric sciences and carbon dioxide research programs are part of the Environmental Sciences Division (ESD). One of the central missions of the division is to provide the DOE with scientifically defensible information on the local, regional, and global distributions of energy-related pollutants and their effects on climate. This information is vital to the definition and implementation of a sound national energy strategy. This volume reports on the progress and status of all OHER atmospheric science and climate research projects at the Pacific Northwest Laboratory (PNL). PNL has had a long history of technical leadership in the atmospheric sciences research programs within OHER. Within the ESD, the Atmospheric Chemistry Program (ACP) continues DOE`s long-term commitment to study the continental and oceanic fates of energy-related air pollutants. Research through direct measurement, numerical modeling, and laboratory studies in the ACP emphasizes the long-range transport, chemical transformation, and removal of emitted pollutants, oxidant species, nitrogen-reservoir species, and aerosols. The Atmospheric Studies in Complex Terrain (ASCOT) program continues to apply basic research on density-driven circulations and on turbulent mixing and dispersion in the atmospheric boundary layer to the micro- to mesoscale meteorological processes that affect air-surface exchange and to emergency preparedness at DOE and other facilities. Research at PNL provides basic scientific underpinnings to DOE`s program of global climate research. Research projects within the core carbon dioxide and ocean research programs are now integrated with those in the Atmospheric Radiation Measurements (ARM), the Computer Hardware, Advanced Mathematics and Model Physics (CHAMMP), and Quantitative Links programs to form DOE`s contribution to the US Global Change Research Program.

  3. Solvent use in private research laboratories in Japan: comparison with the use in public research laboratories and on production floors in industries.

    Science.gov (United States)

    Hanada, Takaaki; Zaitsu, Ai; Kojima, Satoshi; Ukai, Hirohiko; Nagasawa, Yasuhiro; Takada, Shiro; Kawakami, Takuya; Ohashi, Fumiko; Ikeda, Masayuki

    2014-01-01

    Solvents used in production facility-affiliated private laboratories have been seldomly reported. This study was initiated to specify solvent use characteristics in private laboratories in comparison with the use in public research laboratories and on production floors. Elucidation of the applicability of conclusions from a public laboratory survey to private institutions is not only of scientific interest but also of practical importance. A survey on use of 47 legally stipulated organic solvents was conducted. The results were compiled for April 2011 to March 2013. Through sorting, data were available for 479 unit workplaces in private laboratories. Similar sorting for April 2012 to March 2013 was conducted for public research laboratories (e.g., national universities) and production floors (in private enterprises) to obtain 621 and 937 cases, respectively. Sampling of workroom air followed by capillary gas-chromatographic analyses for solvents was conducted in accordance with regulatory requirements. More than one solvent was usually detected in the air of private laboratories. With regard to solvent types, acetone, methyl alcohol, chloroform and hexane were prevalently used in private laboratories, and this was similar to the case of public laboratories. Prevalent use of ethyl acetate was unique to private laboratories. Toluene use was less common both in private and public laboratories. The prevalence of administrative control class 1 (i.e., an adequately controlled environment) was higher in laboratories (both private and public) than production floors. Solvent use patterns are similar in private and public laboratories, except that the use of mixtures of solvents is substantially more popular in private laboratories than in public laboratories.

  4. Pacific Northwest Laboratory annual report for 1992 to the DOE Office of Energy Research

    Energy Technology Data Exchange (ETDEWEB)

    Schrempf, R.E. (ed.)

    1993-04-01

    Within the US Department of Energy's (DOE's) Office of Health and Environmental Research (OHER), the atmospheric sciences and carbon dioxide research programs are part of the Environmental Sciences Division (ESD). One of the central missions of the division is to provide the DOE with scientifically defensible information on the local, regional, and global distributions of energy-related pollutants and their effects on climate. This information is vital to the definition and implementation of a sound national energy strategy. This volume reports on the progress and status of all OHER atmospheric science and climate research projects at the Pacific Northwest Laboratory (PNL). PNL has had a long history of technical leadership in the atmospheric sciences research programs within OHER. Within the ESD, the Atmospheric Chemistry Program (ACP) continues DOE's long-term commitment to study the continental and oceanic fates of energy-related air pollutants. Research through direct measurement, numerical modeling, and laboratory studies in the ACP emphasizes the long-range transport, chemical transformation, and removal of emitted pollutants, oxidant species, nitrogen-reservoir species, and aerosols. The Atmospheric Studies in Complex Terrain (ASCOT) program continues to apply basic research on density-driven circulations and on turbulent mixing and dispersion in the atmospheric boundary layer to the micro- to mesoscale meteorological processes that affect air-surface exchange and to emergency preparedness at DOE and other facilities. Research at PNL provides basic scientific underpinnings to DOE's program of global climate research. Research projects within the core carbon dioxide and ocean research programs are now integrated with those in the Atmospheric Radiation Measurements (ARM), the Computer Hardware, Advanced Mathematics and Model Physics (CHAMMP), and Quantitative Links programs to form DOE's contribution to the US Global Change Research

  5. Educational Technology Research: Substituting Closed-Circuit Television for the Science Laboratory.

    Science.gov (United States)

    Menis, Yosef

    1982-01-01

    Suggests a practical approach for coping with training students in laboratory skill through the use of videotaped (VTR) materials and discusses the technical advantages of using VTR as opposed to laboratory research. Six references are provided. (MER)

  6. Open Air Laboratories (OPAL): A community-driven research programme

    Energy Technology Data Exchange (ETDEWEB)

    Davies, L., E-mail: l.davies@imperial.ac.uk [Imperial College London, London SW7 2AZ (United Kingdom); Bell, J.N.B.; Bone, J.; Head, M.; Hill, L. [Imperial College London, London SW7 2AZ (United Kingdom); Howard, C. [Natural History Museum, London SW7 5BD (United Kingdom); Hobbs, S.J. [Environment Department, University of York, Heslington, York YO10 5DD (United Kingdom); Jones, D.T. [Imperial College London, London SW7 2AZ (United Kingdom); Natural History Museum, London SW7 5BD (United Kingdom); Power, S.A. [Imperial College London, London SW7 2AZ (United Kingdom); Rose, N. [Department of Geography, University College London, London WC1E 6BT (United Kingdom); Ryder, C.; Seed, L. [Imperial College London, London SW7 2AZ (United Kingdom); Stevens, G. [Natural History Museum, London SW7 5BD (United Kingdom); Toumi, R.; Voulvoulis, N. [Imperial College London, London SW7 2AZ (United Kingdom); White, P.C.L. [Environment Department, University of York, Heslington, York YO10 5DD (United Kingdom)

    2011-08-15

    OPAL is an English national programme that takes scientists into the community to investigate environmental issues. Biological monitoring plays a pivotal role covering topics of: i) soil and earthworms; ii) air, lichens and tar spot on sycamore; iii) water and aquatic invertebrates; iv) biodiversity and hedgerows; v) climate, clouds and thermal comfort. Each survey has been developed by an inter-disciplinary team and tested by voluntary, statutory and community sectors. Data are submitted via the web and instantly mapped. Preliminary results are presented, together with a discussion on data quality and uncertainty. Communities also investigate local pollution issues, ranging from nitrogen deposition on heathlands to traffic emissions on roadside vegetation. Over 200,000 people have participated so far, including over 1000 schools and 1000 voluntary groups. Benefits include a substantial, growing database on biodiversity and habitat condition, much from previously unsampled sites particularly in urban areas, and a more engaged public. - Highlights: > Environmental research conducted jointly by the public and scientists. > Over 200,000 people involved, 8000 sites surveyed, uncertainty minimised. > New insights into urban pollution. > A more engaged and informed society. - Research is enriched where the public and scientists work together.

  7. Chemistry and materials science progress report. Weapons-supporting research and laboratory directed research and development: FY 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    This report covers different materials and chemistry research projects carried out a Lawrence Livermore National Laboratory during 1995 in support of nuclear weapons programs and other programs. There are 16 papers supporting weapons research and 12 papers supporting laboratory directed research.

  8. RF Anechoic Chambers, Tri-Service Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — In collaboration with the Navy, there are 12 RF Anechoic and static free exposure chambers located at TSRL. These chambers cover the majority of the RF spectrum and...

  9. Large-Scale Laboratory Facility For Sediment Transport Research

    Data.gov (United States)

    Federal Laboratory Consortium — Effective design and maintenance of inlet navigation and shore protection projects require accurate estimates of the quantity of sand that moves along the beach. The...

  10. Low-gravity Orbiting Research Laboratory Environment Potential Impact on Space Biology Research

    Science.gov (United States)

    Jules, Kenol

    2006-01-01

    One of the major objectives of any orbital space research platform is to provide a quiescent low gravity, preferably a zero gravity environment, to perform fundamental as well as applied research. However, small disturbances exist onboard any low earth orbital research platform. The impact of these disturbances must be taken into account by space research scientists during their research planning, design and data analysis in order to avoid confounding factors in their science results. The reduced gravity environment of an orbiting research platform in low earth orbit is a complex phenomenon. Many factors, among others, such as experiment operations, equipment operation, life support systems and crew activity (if it is a crewed platform), aerodynamic drag, gravity gradient, rotational effects as well as the vehicle structural resonance frequencies (structural modes) contribute to form the overall reduced gravity environment in which space research is performed. The contribution of these small disturbances or accelerations is precisely why the environment is NOT a zero gravity environment, but a reduced acceleration environment. This paper does not discuss other factors such as radiation, electromagnetic interference, thermal and pressure gradient changes, acoustic and CO2 build-up to name a few that affect the space research environment as well, but it focuses solely on the magnitude of the acceleration level found on orbiting research laboratory used by research scientists to conduct space research. For ease of analysis this paper divides the frequency spectrum relevant to most of the space research disciplines into three regimes: a) quasi-steady, b) vibratory and c) transient. The International Space Station is used as an example to illustrate the point. The paper discusses the impact of these three regimes on space biology research and results from space flown experiments are used to illustrate the potential negative impact of these disturbances (accelerations

  11. Research and Teaching: The Impact of a Four-Step Laboratory Pedagogical Framework on Biology Students' Perceptions of Laboratory Skills, Knowledge, and Interest in Research

    Science.gov (United States)

    McLaughlin, Jacqueline Shea; Favre, David E.; Weinstein, Suzanne E.; Goedhart, Christine M.

    2017-01-01

    Authentic undergraduate research laboratory experiences are essential to aid in the implementation of science education reform mandates and to effectively train a new generation of biology students. Here we present assessment data on a unique four-step laboratory pedagogical framework that allows students to develop scientific thinking and…

  12. Signal and Image Processing Research at the Lawrence Livermore National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, R S; Poyneer, L A; Kegelmeyer, L M; Carrano, C J; Chambers, D H; Candy, J V

    2009-06-29

    Lawrence Livermore National Laboratory is a large, multidisciplinary institution that conducts fundamental and applied research in the physical sciences. Research programs at the Laboratory run the gamut from theoretical investigations, to modeling and simulation, to validation through experiment. Over the years, the Laboratory has developed a substantial research component in the areas of signal and image processing to support these activities. This paper surveys some of the current research in signal and image processing at the Laboratory. Of necessity, the paper does not delve deeply into any one research area, but an extensive citation list is provided for further study of the topics presented.

  13. Application of short-range photogrammetry for monitoring seepage erosion of riverbank by laboratory experiments

    Science.gov (United States)

    Masoodi, A.; Noorzad, A.; Majdzadeh Tabatabai, M. R.; Samadi, A.

    2018-03-01

    Temporal and spatial monitoring play a significant role in evaluating and examining the riverbank morphology and its spatiotemporal changes. Unlike the terrestrial laser scanners, other previously used methods such as satellite images, total station surveying, and erosion pins have limited application to quantify the small-scale bank variations due to the lack of rapid survey and resolution in data acquisition. High cost, lack of availability, specialized equipment and hard movement of laser scanners make it necessary to develop new accurate, economical and easily available methods. The present study aims to test the Kinect photogrametric technology for measuring and assessing riverbank variations in laboratory environment. For this purpose, three models of layered soil blocks for three different levels of groundwater (i.e. 24, 34 and 44 cm) were designed to investigate the seepage erosion behavior experimentally. The results indicate the high accuracy of Kinect in measuring the bank erosion cavity dimensions (i.e., 0.5% error) with high spatial resolution data (i.e. 300,000 points per frame). The high speed of Kinect in riverbank scanning enables the analysis of time variations of mechanisms such as seepage erosion which occurs rather rapidly. The results confirmed that there is a power relationship between the seepage gradient and the time of the bank failure with a determination coefficient of 0.97. Moreover, an increase in the level of groundwater on the riverbank increases the rate of undercutting retreat that caused more rapid failure of the riverbank.

  14. Laboratory Directed Research and Development Program FY2016 Annual Summary of Completed Projects

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2017-03-30

    ORNL FY 2016 Annual Summary of Laboratory Directed Research and Development Program (LDRD) Completed Projects. The Laboratory Directed Research and Development (LDRD) program at ORNL operates under the authority of DOE Order 413.2C, “Laboratory Directed Research and Development” (October 22, 2015), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. The LDRD program funds are obtained through a charge to all Laboratory programs. ORNL reports its status to DOE in March of each year.

  15. Sandia National Laboratories land use permit for operations at Oliktok Alaska Long Range Radar Station.

    Energy Technology Data Exchange (ETDEWEB)

    Catechis, Christopher Spyros

    2013-02-01

    The property subject to this Environmental Baseline Survey (EBS) is located at the Oliktok Long Range Radar Station (LRRS). The Oliktok LRRS is located at 70À 30 W latitude, 149À 53 W longitude. It is situated at Oliktok Point on the shore of the Beaufort Sea, east of the Colville River. The purpose of this EBS is to document the nature, magnitude, and extent of any environmental contamination of the property; identify potential environmental contamination liabilities associated with the property; develop sufficient information to assess the health and safety risks; and ensure adequate protection for human health and the environment related to a specific property.

  16. Research at the University of Kentucky Accelerator Laboratory

    Science.gov (United States)

    Hicks, S. F.; Kovash, M. A.

    The Department of Physics and Astronomy at the University of Kentucky operates a 7-MV CN Van de Graaff accelerator that produces primary beams of protons, deuterons, and helium ions. An in-terminal pulsing and bunching system operates at 1.875 MHz and is capable of providing 1 ns beam bunches at an average current of several microamperes. Nearly all ongoing research programs involve secondary pulsed neutrons produced with gas cells containing deuterium or tritium, as well as with a variety of solid targets. Most experiments are performed at a target station positioned over a deep pit, so as to reduce the background created by backscattered neutrons. Recent experiments will be described; these include: measurements of n-p scattering total cross sections from En= 90 to 1800 keV to determine the n-p effective range parameter; the response of the plastic scintillator BC-418 below 1 MeV to low-energy recoil protons; n-p radiative capture cross sections important for our understanding of nucleosynthesis approximately 2 minutes after the occurrence of the Big Bang; γ-ray spectroscopy following inelastic neutron scattering to study nuclear structure relevant to double-β decay and to understand the role of phonon-coupled excitations in weakly deformed nuclei; and measurements of neutron elastic and inelastic scattering cross sections for nuclei that are important for energy production and for our global understanding of the interaction of neutrons with matter.

  17. Laboratory Directed Research and Development Annual Report - Fiscal Year 2000

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, Darrell R.; Hughes, Pamela J.; Pearson, Erik W.

    2001-04-01

    The projects described in this report represent the Laboratory's investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. In accordance with DOE guidelines, the report provides, a) a director's statement, b) an overview of the laboratory's LDRD program, including PNNL's management process and a self-assessment of the program, c) a five-year project funding table, and d) project summaries for each LDRD project.

  18. III-V Infrared Research at the Jet Propulsion Laboratory

    Science.gov (United States)

    Gunapala, S. D.; Ting, D. Z.; Hill, C. J.; Soibel, A.; Liu, John; Liu, J. K.; Mumolo, J. M.; Keo, S. A.; Nguyen, J.; Bandara, S. V.; hide

    2009-01-01

    Jet Propulsion Laboratory is actively developing the III-V based infrared detector and focal plane arrays (FPAs) for NASA, DoD, and commercial applications. Currently, we are working on multi-band Quantum Well Infrared Photodetectors (QWIPs), Superlattice detectors, and Quantum Dot Infrared Photodetector (QDIPs) technologies suitable for high pixel-pixel uniformity and high pixel operability large area imaging arrays. In this paper we report the first demonstration of the megapixel-simultaneously-readable and pixel-co-registered dual-band QWIP focal plane array (FPA). In addition, we will present the latest advances in QDIPs and Superlattice infrared detectors at the Jet Propulsion Laboratory.

  19. The International Space Station as a Research Laboratory: A View to 2010 and Beyond

    Science.gov (United States)

    Uri, John J.; Sotomayor, Jorge L.

    2007-01-01

    Assembly of International Space Station (ISS) is expected to be complete in 2010, with operations planned to continue through at least 2016. As we move nearer to assembly complete, replanning activities by NASA and ISS International Partners have been completed and the final complement of research facilities on ISS is becoming more certain. This paper will review pans for facilities in the US On-orbit Segment of ISS, including contributions from International Partners, to provide a vision of the research capabilities that will be available starting in 2010. At present, in addition to research capabilities in the Russian segment, the United States Destiny research module houses nine research facilities or racks. These facilities include five multi-purpose EXPRESS racks, two Human Research Facility (HRF) racks, the Microgravity Science Glovebox (MSG), and the Minus Eighty-degree Laboratory Freezer for ISS (MELFI), enabling a wide range of exploration-related applied as well as basic research. In the coming years, additional racks will be launched to augment this robust capability: Combustion Integrated Rack (CIR), Fluids Integrated Rack (FIR), Window Observation Rack Facility (WORF), Microgravity Science Research Rack (MSRR), Muscle Atrophy Research Exercise System (MARES), additional EXPRESS racks and possibly a second MELFI. In addition, EXPRESS Logistics Carriers (ELC) will provide attach points for external payloads. The European Space Agency s Columbus module will contain five research racks and provide four external attach sites. The research racks are Biolab, European Physiology Module (EPM), Fluid Science Lab (FSL), European Drawer System (EDS) and European Transport Carrier (ETC). The Japanese Kibo elements will initially support three research racks, Ryutai for fluid science, Saibo for cell science, and Kobairo for materials research, as well as 10 attachment sites for external payloads. As we look ahead to assembly complete, these new facilities represent

  20. A Place for Materials Science: Laboratory Buildings and Interdisciplinary Research at the University of Pennsylvania

    Science.gov (United States)

    Choi, Hyungsub; Shields, Brit

    2015-01-01

    The Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, was built in 1965 as part of the Advanced Research Projects Agency's (ARPA) Interdisciplinary Laboratories (IDL) program intended to foster interdisciplinary research and training in materials science. The process that led to the construction of the…

  1. Developing a collaborative agenda for humanities and social scientific research on laboratory animal science and welfare.

    OpenAIRE

    Davies, Gail F.; Greenhough, Beth J.; Hobson-West, Pru; Kirk, Robert G.W.; Applebee, Ken; Bellinghan, Laura C.; Berdoy, Manuel; Buller, Henry; Cassaday, Helen J.; Davies, Keith; Diefenbacher, Daniela; Druglitrø, Tone; Escobar, Maria Paula; Friese, Carrie

    2016-01-01

    Improving laboratory animal science and welfare requires both new scientific research and insights from research in the humanities and social sciences. Whilst scientific research provides evidence to replace, reduce and refine procedures involving laboratory animals (the‘3Rs’), work in the humanities and social sciences can help understand the social, economic and cultural processes that enhance or impede humane ways of knowing and working with laboratory animals. However, communication acros...

  2. Holography at the U.S. Army Research Laboratory: Creating a Digital Hologram

    Science.gov (United States)

    2012-09-01

    Holography at the U.S. Army Research Laboratory: Creating a Digital Hologram by Karl K. Klett, Jr., Neal Bambha, and Justin Bickford...MD 20783-1197 ARL-TR-6299 September 2012 Holography at the U.S. Army Research Laboratory: Creating a Digital Hologram Karl K. Klett...Army Research Laboratory: Creating a Digital Hologram 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Karl K

  3. Oak Ridge National Laboratory Health and Safety Long-Range Plan: Fiscal years 1989--1995

    Energy Technology Data Exchange (ETDEWEB)

    1989-06-01

    The health and safety of its personnel is the first concern of ORNL and its management. The ORNL Health and Safety Program has the responsibility for ensuring the health and safety of all individuals assigned to ORNL activities. This document outlines the principal aspects of the ORNL Health and Safety Long-Range Plan and provides a framework for management use in the future development of the health and safety program. Each section of this document is dedicated to one of the health and safety functions (i.e., health physics, industrial hygiene, occupational medicine, industrial safety, nuclear criticality safety, nuclear facility safety, transportation safety, fire protection, and emergency preparedness). Each section includes functional mission and objectives, program requirements and status, a summary of program needs, and program data and funding summary. Highlights of FY 1988 are included.

  4. Laboratory Directed Research and Development FY2010 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, K J

    2011-03-22

    A premier applied-science laboratory, Lawrence Livermore National Laboratory (LLNL) has at its core a primary national security mission - to ensure the safety, security, and reliability of the nation's nuclear weapons stockpile without nuclear testing, and to prevent and counter the spread and use of weapons of mass destruction: nuclear, chemical, and biological. The Laboratory uses the scientific and engineering expertise and facilities developed for its primary mission to pursue advanced technologies to meet other important national security needs - homeland defense, military operations, and missile defense, for example - that evolve in response to emerging threats. For broader national needs, LLNL executes programs in energy security, climate change and long-term energy needs, environmental assessment and management, bioscience and technology to improve human health, and for breakthroughs in fundamental science and technology. With this multidisciplinary expertise, the Laboratory serves as a science and technology resource to the U.S. government and as a partner with industry and academia. This annual report discusses the following topics: (1) Advanced Sensors and Instrumentation; (2) Biological Sciences; (3) Chemistry; (4) Earth and Space Sciences; (5) Energy Supply and Use; (6) Engineering and Manufacturing Processes; (7) Materials Science and Technology; Mathematics and Computing Science; (8) Nuclear Science and Engineering; and (9) Physics.

  5. Air Force Research Laboratory Success Stories : A Review of 2004

    Science.gov (United States)

    2004-01-01

    Phase IV performed a waveform characterization of the entire radar system. U Gain in the Electrico i Laboratory System Work sponsored by the AFRL...permanent disability, or death in recreational and professional activities that incorporate speed and agility, like auto racing, motorcycling, and skiing

  6. Research Laboratory of Electronics Progress Report Number 133

    Science.gov (United States)

    1991-08-01

    insta- bilities. Such instabilities are believed to be a Sponsor source of some types of observed planetary, solar National Aeronautics and Space...laboratories of E.N.E.A. ( Energia ceedings of the International Sherwood Theory Nucleare e Energie Alternative), as well as in- Meeting, Williamsburg, Virginia

  7. Introduction to Biological Research: A Laboratory Course in Microbiology

    Science.gov (United States)

    Dudley, Aimee M.; Cardozo, David Lopes

    2006-01-01

    In this paper, the authors describe their development of an introductory laboratory course in microbiology that is geared towards students in grades 8-10. The course was developed as part of the Mentoring for Science Program at Harvard Medical School, an outreach program created by the Minority Faculty Development Program, directed towards…

  8. From Cookbook to Research: Redesigning an Advanced Biochemistry Laboratory

    Science.gov (United States)

    Boyd-Kimball, Debra; Miller, Keith R.

    2018-01-01

    Laboratory courses are often designed using step-by-step protocols which encourage students to conduct experiments without thinking about what they are doing or why they are doing it. Such course design limits the growth of our students as scientists and can make it more difficult for a student to transition to the expectations of a research…

  9. Measurement Instruments and Software Used in Biotribology Research Laboratory

    Directory of Open Access Journals (Sweden)

    Tyurin Andrei

    2015-07-01

    Full Text Available Precision measurements of friction processes have a key role in a variety of industrial processes. The emergence of fine electronic circuit techniques greatly expands capabilities of control. There are some difficulties for their full implementation today, especially when it regards the accuracy and frequency of measurements. The motion-measuring method in real-time system is considered in this article, paying special attention to increased accuracy. This method is based on rapid analog digital converter (ADC, transmission program and digital signal processor (DSP algorithms. Description of laboratory devices is included: Tribal-T and universal friction machine (MTU-01 designed for “Pin on disc” tests. Great emphasis is placed on the usability of accelerometers. The present study examined the collected data via laboratory system for data acquisition and control, and processing it in the laboratory of Biotribology. Laboratory supervisory control and data acquisition (SCADA algorithms is described below. Task of regulation is not considered. This paper describes only methods of automatic control theory to analyze the frictional quality.

  10. Leading Antibacterial Laboratory Research by Integrating Conventional and Innovative Approaches: The Laboratory Center of the Antibacterial Resistance Leadership Group.

    Science.gov (United States)

    Manca, Claudia; Hill, Carol; Hujer, Andrea M; Patel, Robin; Evans, Scott R; Bonomo, Robert A; Kreiswirth, Barry N

    2017-03-15

    The Antibacterial Resistance Leadership Group (ARLG) Laboratory Center (LC) leads the evaluation, development, and implementation of laboratory-based research by providing scientific leadership and supporting standard/specialized laboratory services. The LC has developed a physical biorepository and a virtual biorepository. The physical biorepository contains bacterial isolates from ARLG-funded studies located in a centralized laboratory and they are available to ARLG investigators. The Web-based virtual biorepository strain catalogue includes well-characterized gram-positive and gram-negative bacterial strains published by ARLG investigators. The LC, in collaboration with the ARLG Leadership and Operations Center, developed procedures for review and approval of strain requests, guidance during the selection process, and for shipping strains from the distributing laboratories to the requesting investigators. ARLG strains and scientific and/or technical guidance have been provided to basic research laboratories and diagnostic companies for research and development, facilitating collaboration between diagnostic companies and the ARLG Master Protocol for Evaluating Multiple Infection Diagnostics (MASTERMIND) initiative for evaluation of multiple diagnostic devices from a single patient sampling event. In addition, the LC has completed several laboratory-based studies designed to help evaluate new rapid molecular diagnostics by developing, testing, and applying a MASTERMIND approach using purified bacterial strains. In collaboration with the ARLG's Statistical and Data Management Center (SDMC), the LC has developed novel analytical strategies that integrate microbiologic and genetic data for improved and accurate identification of antimicrobial resistance. These novel approaches will aid in the design of future ARLG studies and help correlate pathogenic markers with clinical outcomes. The LC's accomplishments are the result of a successful collaboration with the ARLG

  11. Revisiting Truth or Triviality: The External Validity of Research in the Psychological Laboratory.

    Science.gov (United States)

    Mitchell, Gregory

    2012-03-01

    Anderson, Lindsay, and Bushman (1999) compared effect sizes from laboratory and field studies of 38 research topics compiled in 21 meta-analyses and concluded that psychological laboratories produced externally valid results. A replication and extension of Anderson et al. (1999) using 217 lab-field comparisons from 82 meta-analyses found that the external validity of laboratory research differed considerably by psychological subfield, research topic, and effect size. Laboratory results from industrial-organizational psychology most reliably predicted field results, effects found in social psychology laboratories most frequently changed signs in the field (from positive to negative or vice versa), and large laboratory effects were more reliably replicated in the field than medium and small laboratory effects. © The Author(s) 2012.

  12. What Laboratory Research has Told Us about Dolphin Cognition

    OpenAIRE

    Herman, Louis M.

    2010-01-01

    Studies of sensory, cognitive, and communicative skills of bottlenose dolphins (Tursiops truncatus) were carried out over a 34-year period at the Kewalo Basin Marine Mammal Laboratory in Honolulu. Findings on sensory skills included fine discrimination of auditory frequency differences andauditory duration, good visual resolution capabilities in water and in air, and sharing of object recognition across the senses of vision and echolocation. Short-term memory for auditory and visual materials...

  13. Laboratory Directed Research and Development Annual Report for 2009

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, Pamela J.

    2010-03-31

    This report documents progress made on all LDRD-funded projects during fiscal year 2009. As a US Department of Energy (DOE) Office of Science (SC) national laboratory, Pacific Northwest National Laboratory (PNNL) has an enduring mission to bring molecular and environmental sciences and engineering strengths to bear on DOE missions and national needs. Their vision is to be recognized worldwide and valued nationally for leadership in accelerating the discovery and deployment of solutions to challenges in energy, national security, and the environment. To achieve this mission and vision, they provide distinctive, world-leading science and technology in: (1) the design and scalable synthesis of materials and chemicals; (2) climate change science and emissions management; (3) efficient and secure electricity management from generation to end use; and (4) signature discovery and exploitation for threat detection and reduction. PNNL leadership also extends to operating EMSL: the Environmental Molecular Sciences Laboratory, a national scientific user facility dedicated to providing itnegrated experimental and computational resources for discovery and technological innovation in the environmental molecular sciences.

  14. Sequim Marine Research Laboratory routine environmental measurements during CY-1978. [Monitoring for laboratory-related radioactivity and pollutants in environment

    Energy Technology Data Exchange (ETDEWEB)

    Houston, J.R.; Blumer, P.J.

    1979-03-01

    Environmental data collected during 1978 in the vicinity of the Marine Research Laboratory show continued compliance with all applicable state and federal regulations and furthermore show no detectable change from conditions that existed in previous years. Samples collected for radiological analysis included soil, drinking water, bay water, clams, and seaweed. Radiation dose rates at 1 meter aboveground were also measured.

  15. The management of research institutions: A look at government laboratories

    Science.gov (United States)

    Mark, H.; Levine, A.

    1984-01-01

    Technology development; project management; employment patterns; research productivity; legal status of support services; functions of senior executives; the role of the sponsoring agency; research diversification; obstacles to technical innovation; organizational structures; and personnel management are addressed.

  16. Use of Laboratory Animals in Biomedical and Behavioral Research.

    Science.gov (United States)

    Ministry of Education, Addis Ababa (Ethiopia).

    The use of animals in scientific research has been a controversial issue for over a hundred years. Research with animals has saved human lives, lessened human suffering, and advanced scientific understanding, yet that same research can cause pain and distress for the animals involved and may result in their death. It is hardly surprising that…

  17. Sandia National Laboratories, Tonopah Test Range Fire Control Bunker (Building 09-51): Photographs and Written Historical and Descriptive Data

    Energy Technology Data Exchange (ETDEWEB)

    Ullrich, Rebecca A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Corporate Archives and History Program

    2017-08-01

    The Fire Control Bunker (Building 09-51) is a contributing element to the Sandia National Laboratories (SNL) Tonopah Test Range (TTR) Historic District. The SNL TTR Historic District played a significant role in U.S. Cold War history in the areas of stockpile surveillance and non-nuclear field testing of nuclear weapons design. The district covers approximately 179,200 acres and illustrates Cold War development testing of nuclear weapons components and systems. This report includes historical information, architectural information, sources of information, project information, maps, blueprints, and photographs.

  18. Floodplain Assessment for the Proposed Outdoor Fire Range Upgrades at TA-72 in Lower Sandia Canyon, Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Hathcock, Charles D. [Los Alamos National Laboratory

    2012-08-27

    Los Alamos National Laboratory (LANL) is preparing to implement actions in Sandia Canyon at Technical Area (TA) 72. Los Alamos National Security (LANS) biologists conducted a floodplain determination and this project is partially located within a 100-year floodplain. The proposed project is to upgrade the existing outdoor shooting range facilities at TA-72. These upgrades will result in increased safety and efficiencies in the training for Protective Force personnel. In order to remain current on training requirements, the firing ranges at TA-72 will be upgraded which will result in increased safety and efficiencies in the training for Protective Force personnel (Figure 1). These upgrades will allow for an increase in class size and more people to be qualified at the ranges. Some of these upgrades will be built within the 100-year floodplain. The upgrades include: concrete pads for turning target systems and shooting positions, new lighting to illuminate the firing range for night fire, a new speaker system for range operations, canopies at two locations, an impact berm at the far end of the 300-yard mark, and a block wall for road protection.

  19. MODERNIZATION OF LABORATORY STAND OF ASYNHRONOUS ELECTRIC DRIVE RESEARCH

    Directory of Open Access Journals (Sweden)

    Yu. A. Krysan

    2014-07-01

    The worked out course of laboratory works allows to conduct timing of switching of degrees of resistances and construction of electromechanical descriptions slip-ring induction motoring and also to design his work using the SimPowerSystems libraries of МATLAB Simulink package. Creation of program algorithm and its realization as a EASYSOFT program environment are performed. Verification of rightness of the program writing and tuning of all program elements parameters are done. It is shown that the removal of the real current is in the phase of rotor (by means of digital oscillograph and it is don’t the design comparison of its results

  20. Speakers’ comfort and voice level variation in classrooms: Laboratory research

    DEFF Research Database (Denmark)

    Pelegrin Garcia, David; Brunskog, Jonas

    2012-01-01

    from 0.93 dB/dB, with free speech, to 0.1 dB/dB with other less demanding communication tasks as reading and talking at short distances. The room effect for some individuals can be as strong as 1.7 dB/dB. A questionnaire investigation showed that the acoustic comfort for talking in classrooms......Teachers adjust their voice levels under different classroom acoustics conditions, even in the absence of background noise. Laboratory experiments have been conducted in order to understand further this relationship and to determine optimum room acoustic conditions for speaking. Under simulated...

  1. National Renewable Energy Laboratory (NREL) 2006 Research Review

    Energy Technology Data Exchange (ETDEWEB)

    2007-07-01

    This 2006 issue of the NREL Research Review again reveals just how vital and diverse our research portfolio has become. Our feature story looks at how our move to embrace the tenants of "translational research" is strengthening our ability to meet the nation's energy goals. By closing the gap between basic science and applied research and development (R&D)--and focusing a bright light on the valuable end uses of our work--translational research promises to shorten the time it takes to push new technology off the lab bench and into the marketplace. This issue also examines our research into fuels of the future and our computer modeling of wind power deployment, both of which point out the real-world benefits of our work.

  2. Frontiers: Research Highlights 1946-1996 [50th Anniversary Edition. Argonne National Laboratory

    Science.gov (United States)

    1996-01-01

    This special edition of 'Frontiers' commemorates Argonne National Laboratory's 50th anniversary of service to science and society. America's first national laboratory, Argonne has been in the forefront of U.S. scientific and technological research from its beginning. Past accomplishments, current research, and future plans are highlighted.

  3. Redefining Authentic Research Experiences in Introductory Biology Laboratories and Barriers to Their Implementation

    Science.gov (United States)

    Spell, Rachelle M.; Guinan, Judith A.; Miller, Kristen R.; Beck, Christopher W.

    2014-01-01

    Incorporating authentic research experiences in introductory biology laboratory classes would greatly expand the number of students exposed to the excitement of discovery and the rigor of the scientific process. However, the essential components of an authentic research experience and the barriers to their implementation in laboratory classes are…

  4. Frontiers: Research highlights 1946-1996 [50th Anniversary Edition. Argonne National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This special edition of 'Frontiers' commemorates Argonne National Laboratory's 50th anniversary of service to science and society. America's first national laboratory, Argonne has been in the forefront of U.S. scientific and technological research from its beginning. Past accomplishments, current research, and future plans are highlighted.

  5. Evaluation of Radiometers Deployed at the National Renewable Energy Laboratory's Solar Radiation Research Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Habte, Aron; Wilcox, Stephen; Stoffel, Thomas

    2015-12-23

    This study analyzes the performance of various commercially available radiometers used for measuring global horizontal irradiances and direct normal irradiances. These include pyranometers, pyrheliometers, rotating shadowband radiometers, and a pyranometer with fixed internal shading and are all deployed at the National Renewable Energy Laboratory's Solar Radiation Research Laboratory. Data from 32 global horizontal irradiance and 19 direct normal irradiance radiometers are presented. The radiometers in this study were deployed for one year (from April 1, 2011, through March 31, 2012) and compared to measurements from radiometers with the lowest values of estimated measurement uncertainties for producing reference global horizontal irradiances and direct normal irradiances.

  6. Lightweight Portable Plasma Medical Device - Plasma Engineering Research Laboratory

    Science.gov (United States)

    2014-10-01

    6. “Texas A&M University-Corpus Christi researcher fights drug -resistant researcher with plasma technology”, Operating Room Today – OR TODAY Magazine...June 2013. (Link: http://ortoday.com/texas-am-researcher-fights- drug - resistant-cold-plasma-technology/) 7. “Killer “Superbugs” are No Match for...Symposium: Course Design for the Millennial Student, Texas A&M University – Corpus Christi, 2011. (Showcased by the Center for Faculty Excellence

  7. Lawrence Berkeley Laboratory research highlights for FY 1975

    Energy Technology Data Exchange (ETDEWEB)

    Sessler, Andrew M.

    1978-01-01

    Brief, nontechnical reviews are presented of work in the following areas: solar energy projects, fusion research, silicon cell research, superconducting magnetometers, psi particles, positron--electron project (PEP), pulsar measurements, nuclear dynamics, element 106, computer control of accelerators, the Bevalac biomedical facility, blood--lipid analysis, and bungarotoxin and the brain. Financial data and personnel lists are given, along with citations to well over a thousand research papers. (RWR)

  8. Behavioural science at work for Canada: National Research Council laboratories.

    Science.gov (United States)

    Veitch, Jennifer A

    2007-03-01

    The National Research Council is Canada's principal research and development agency. Its 20 institutes are structured to address interdisciplinary problems for industrial sectors, and to provide the necessary scientific infrastructure, such as the national science library. Behavioural scientists are active in five institutes: Biological Sciences, Biodiagnostics, Aerospace, Information Technology, and Construction. Research topics include basic cellular neuroscience, brain function, human factors in the cockpit, human-computer interaction, emergency evacuation, and indoor environment effects on occupants. Working in collaboration with NRC colleagues and with researchers from universities and industry, NRC behavioural scientists develop knowledge, designs, and applications that put technology to work for people, designed with people in mind.

  9. Design and use of a mobile, x-band, high range resolution, radar research facility

    CSIR Research Space (South Africa)

    De Witt, JJ

    2012-10-01

    Full Text Available High range resolution (HRR) radar measurements can provide important feature information when performing non-cooperative target recognition. This paper presents a joint development of a mobile, X-band, HRR research radar facility, by the research...

  10. Four Decades of Ground-Breaking Research in the Reproductive and Developmental Sciences: The Infant Primate Research Laboratory at the University of Washington National Primate Research Center

    Science.gov (United States)

    Burbacher, Thomas M.; Grant, Kimberly S.; Worlein, Julie; Ha, James; Curnow, Eliza; Juul, Sandra; Sackett, Gene P.

    2017-01-01

    The Infant Primate Research Laboratory (IPRL) was established in the 1970s at the University of Washington as a visionary project of Dr. Gene (Jim) P. Sackett. Supported by a collaboration between the Washington National Primate Research Center and the Center on Human Health and Disability, the IPRL operates under the principle that learning more about the causes of abnormal development in macaque monkeys will provide important insights into mechanisms underlying childhood neurodevelopmental disorders. Over the past forty years, a broad range of research projects have been conducted at the IPRL. Some have described the normal expression of species-typical behaviors in nursery-reared macaques while others have focused on specific issues in perinatal medicine and research. This article will review the unique history of the IPRL and the scientific contributions produced by research conducted in the laboratory. Past and present investigations at the IPRL have explored the consequences of adverse early rearing, low-birth-weight, prematurity, epilepsy, chemical/drug exposure, viral infection, diarrheal disease, vaccine safety, assisted reproductive technologies and perinatal hypoxia on growth and development. New directions of investigation include the production of a transgenic primate model using our embryonic stem cell-based technology to better understand and treat heritable forms of human mental retardation such as fragile X. PMID:23873400

  11. Developing Therapies for Brain Tumors: The Impact of the Johns Hopkins Hunterian Neurosurgical Research Laboratory.

    Science.gov (United States)

    Brem, Henry; Sankey, Eric W; Liu, Ann; Mangraviti, Antonella; Tyler, Betty M

    2017-01-01

    The Johns Hopkins Hunterian Neurosurgical Laboratory at the Johns Hopkins University School of Medicine was created in 1904 by Harvey Cushing and William Halsted and has had a long history of fostering surgical training, encouraging basis science research, and facilitating translational application. Over the past 30 years, the laboratory has addressed the paucity of brain tumor therapies. Pre-clinical work from the laboratory led to the development of carmustine wafers with initial US Food and Drug Administration (FDA) approval in 1996. Combining carmustine wafers, radiation, and temozolomide led to a significant increase in the median survival of patients with glioblastoma. The laboratory has also developed microchips and immunotherapy to further extend survival in this heretofore underserved population. These achievements were made possible by the dedication, commitment, and creativity of more than 300 trainees of the Hunterian Neurosurgical Laboratory. The laboratory demonstrates the beneficial influence of research experience as well its substantial impact on the field of biomedical research.

  12. Materials research at selected Japanese laboratories. Based on a 1992 visit: Overview, summary of highlights, notes on laboratories and topics

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    I visited Japan from June 29 to August 1, 1992. The purpose of this visit was to assess the status of materials science research at selected governmental, university and industrial laboratories and to established acquaintances with Japanese researchers. The areas of research covered by these visits included ceramics, oxide superconductors, intermetallics alloys, superhard materials and diamond films, high-temperature materials and properties, mechanical properties, fracture, creep, fatigue, defects, materials for nuclear reactor applications and irradiation effects, high pressure synthesis, self-propagating high temperature synthesis, microanalysis, magnetic properties and magnetic facilities, and surface science.

  13. Research Triangle Park, NC Laboratory at a Glance

    Science.gov (United States)

    Among many other things, EPA's Research Triangle Park scientists simulate many different types of air pollution under varying meteorological conditions and study the health effects of air pollution mixtures.

  14. Publication bias in laboratory animal research by non-publication of “negative” results

    Directory of Open Access Journals (Sweden)

    Cornelis J.F Van Noorden

    2013-04-01

    Full Text Available An interesting publication for the readership of The All Results Journal appeared recently, focused on publication bias in laboratory animal research. The article highlight the preference to publish results that show effects of treatment over publication of lack of effects of treatment. The authors do not have hard evidence for the preference to publish effects rather than the lack of effects but show indirect evidence for this phenomenon by interviewing all known laboratory animal researchers in The Netherlands in an internet-based survey. In the survey, a total of 454 researchers responded, which is 14, 24% of the estimated number of laboratory animal researchers in The Netherlands

  15. Ecological research at the Savannah River Ecology Laboratory. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-05-01

    Research is organized around two major programs: thermal and aquatic stress and mineral cycling. These programs are strengthened by a previously established foundation of basic ecological knowledge. Research in basic ecology continues to be a major component of all SREL environmental programs. Emphasis in all programs has been placed upon field-oriented research relating to regional and local problems having broad ecological significance. For example, extensive research has been conducted in the Par Pond reservoir system and the Savannah River swamp, both of which have received thermal effluent, heavy metals, and low levels of radioisotopes. Furthermore, the availability of low levels of plutonium and uranium in both terrestrial and aquatic environments on the Savannah River Plant (SRP) has provided an unusual opportunity for field research in this area. The studies seek to document the effects, to determine the extent of local environmental problems, and to establish predictable relationships which have general applicability. In order to accomplish this objective it has been imperative that studies be carried out in the natural, environmentally unaffected areas on the SRP as a vital part of the overall program. Progress is reported in forty-nine studies.

  16. Research Support for the Laboratory for Lightwave Technology

    Science.gov (United States)

    1992-12-31

    completely spherical, unagglomerated, single crystal particles of nano-phase powders. We have done this with alumina, titania, and zirconia . The...were coated to prevent any possible corona effects. With this arrangement it was possible to generate uniform DC electric fields in the 0 to 300KV/m...range. Measurements made with probes under DC fields of up to 300KV/m showed no signs of electric discharge or corona effects. Reflected intensity

  17. Air Force Research Laboratory Success Stories. A Review of 2001

    Science.gov (United States)

    2001-01-01

    properties. After building a prototype of their proposed composite from fiberglass and tiny copper wires, the researchers sent microwaves of the same...cracks, the microcapsules rupture and release the healing agent into the damaged region through capillary action. As the healing agent contacts the

  18. National Renewable Energy Laboratory 2002 Research Review (Booklet)

    Energy Technology Data Exchange (ETDEWEB)

    Cook, G.; Epstein, K.; Brown, H.

    2002-07-01

    America is making a long transition to a future in which conventional, fossil fuel technologies will be displaced by new renewable energy and energy efficiency technologies. This first biannual research review describes NREL's R&D in seven technology areas--biorefineries, transportation, hydrogen, solar electricity, distributed energy, energy-efficient buildings, and low-wind-speed turbines.

  19. Lightweight Portable Plasma Medical Device - Plasma Engineering Research Laboratory

    Science.gov (United States)

    2013-10-01

    data were collected for the analysis of post- treatment bacterial growth means over time. D. Messenger RNA analysis by quantitative real time-PCR...Engineering Research", Texas A&M University Corpus Christi. (September 2010). 29. Texas A&M University Corpus Christi - Facebook Page - Features DOD

  20. University of Illinois at Urbana-Champaign, Materials Research Laboratory progress report for FY 1991

    Energy Technology Data Exchange (ETDEWEB)

    1991-10-01

    The Materials Research Laboratory at the University of Illinois is an interdisciplinary laboratory operated in the College of Engineering. Its focus is the science of materials and it supports research in the areas of condensed matter physics, solid state chemistry, and materials science. This report addresses topics such as: an MRL overview; budget; general programmatic and institutional issues; new programs; research summaries for metallurgy, ceramics, solid state physics, and materials chemistry.

  1. Potato-related research at USDA-ARS laboratories in Washington and Idaho

    Science.gov (United States)

    Potato-related research currently being conducted at three USDA-ARS laboratories in Idaho and Washington is reviewed. Objectives of research programs at the Temperate Tree Fruit & Vegetable Research Unit (Wapato, WA), the Irrigated Agriculture Research and Extension Center (Prosser, WA), and the Sm...

  2. Final report for the Integrated and Robust Security Infrastructure (IRSI) laboratory directed research and development project

    Energy Technology Data Exchange (ETDEWEB)

    Hutchinson, R.L.; Hamilton, V.A.; Istrail, G.G.; Espinoza, J.; Murphy, M.D.

    1997-11-01

    This report describes the results of a Sandia-funded laboratory-directed research and development project titled {open_quotes}Integrated and Robust Security Infrastructure{close_quotes} (IRSI). IRSI was to provide a broad range of commercial-grade security services to any software application. IRSI has two primary goals: application transparency and manageable public key infrastructure. IRSI must provide its security services to any application without the need to modify the application to invoke the security services. Public key mechanisms are well suited for a network with many end users and systems. There are many issues that make it difficult to deploy and manage a public key infrastructure. IRSI addressed some of these issues to create a more manageable public key infrastructure.

  3. Status of the naval research laboratory trace element accelerator mass spectrometer: Characterization of the Pretzel magnet

    Science.gov (United States)

    Knies, D. L.; Grabowski, K. S.; Hubler, G. K.; Treacy, D. J.; DeTurck, T. M.; Enge, H. A.

    1997-02-01

    A novel design for a trace element accelerator mass spectrometer has been developed at the Naval Research Laboratory and is now under construction. It will allow parallel analysis of a broad range of impurities in electronic, biological, and geological materials. The system includes a modified commercial secondary ion mass spectrometer (Physical Electronics, model 6300) as the source of secondary ions, a recombinator consisting of a Pretzel magnet that serves as a tunable notch mass filter, a 3MV Pelletron tandem accelerator, a large electrostatic analyzer, and a split-pole magnetic spectrograph with a 1.5-m-long focal plane. All other ion optical and steering elements are electrostatic, to maintain parallel transmission of different mass species. This paper summarizes the design concept, and describes in some detail the characteristics of the Pretzel magnet.

  4. Ice Crystal Icing Engine Testing in the NASA Glenn Research Center's Propulsion Systems Laboratory: Altitude Investigation

    Science.gov (United States)

    Oliver, Michael J.

    2014-01-01

    The National Aeronautics and Space Administration (NASA) conducted a full scale ice crystal icing turbofan engine test using an obsolete Allied Signal ALF502-R5 engine in the Propulsion Systems Laboratory (PSL) at NASA Glenn Research Center. The test article used was the exact engine that experienced a loss of power event after the ingestion of ice crystals while operating at high altitude during a 1997 Honeywell flight test campaign investigating the turbofan engine ice crystal icing phenomena. The test plan included test points conducted at the known flight test campaign field event pressure altitude and at various pressure altitudes ranging from low to high throughout the engine operating envelope. The test article experienced a loss of power event at each of the altitudes tested. For each pressure altitude test point conducted the ambient static temperature was predicted using a NASA engine icing risk computer model for the given ambient static pressure while maintaining the engine speed.

  5. Bridging the Gap between Instructional and Research Laboratories: Teaching Data Analysis Software Skills through the Manipulation of Original Research Data

    Science.gov (United States)

    Hansen, Sarah J. R.; Zhu, Jieling; Karch, Jessica M.; Sorrento, Cristina M.; Ulichny, Joseph C.; Kaufman, Laura J.

    2016-01-01

    The gap between graduate research and introductory undergraduate teaching laboratories is often wide, but the development of teaching activities rooted within the research environment offers an opportunity for undergraduate students to have first-hand experience with research currently being conducted and for graduate students to develop…

  6. Pacific Northwest Laboratory: Director`s overview of research performed for DOE Office of Health And Environmental Research

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    A significant portion of the research undertaken at Pacific Northwest Laboratory (PNL) is focused on the strategic programs of the US Department of Energy`s (DOE) Office of Health and Environmental Research (OHER). These programs, which include Environmental Processes (Subsurface Science, Ecosystem Function and Response, and Atmospheric Chemistry), Global Change (Climate Change, Environmental Vulnerability, and Integrated Assessments), Biotechnology (Human Genome and Structural Biology), and Health (Health Effects and Medical Applications), have been established by OHER to support DOE business areas in science and technology and environmental quality. PNL uses a set of critical capabilities based on the Laboratory`s research facilities and the scientific and technological expertise of its staff to help OHER achieve its programmatic research goals. Integration of these capabilities across the Laboratory enables PNL to assemble multidisciplinary research teams that are highly effective in addressing the complex scientific and technical issues associated with OHER-sponsored research. PNL research efforts increasingly are focused on complex environmental and health problems that require multidisciplinary teams to address the multitude of time and spatial scales found in health and environmental research. PNL is currently engaged in research in the following areas for these OHER Divisions: Environmental Sciences -- atmospheric radiation monitoring, climate modeling, carbon cycle, atmospheric chemistry, ecological research, subsurface sciences, bioremediation, and environmental molecular sciences; Health Effects and Life Sciences -- cell/molecular biology, and biotechnology; Medical Applications and Biophysical Research -- analytical technology, and radiological and chemical physics. PNL`s contributions to OHER strategic research programs are described in this report.

  7. How Work Positions Affect the Research Activity and Information Behaviour of Laboratory Scientists in the Research Lifecycle: Applying Activity Theory

    Science.gov (United States)

    Kwon, Nahyun

    2017-01-01

    Introduction: This study was conducted to investigate the characteristics of research and information activities of laboratory scientists in different work positions throughout a research lifecycle. Activity theory was applied as the conceptual and analytical framework. Method: Taking a qualitative research approach, in-depth interviews and field…

  8. FY 1999 Laboratory Directed Research and Development annual report

    Energy Technology Data Exchange (ETDEWEB)

    PJ Hughes

    2000-06-13

    A short synopsis of each project is given covering the following main areas of research and development: Atmospheric sciences; Biotechnology; Chemical and instrumentation analysis; Computer and information science; Design and manufacture engineering; Ecological science; Electronics and sensors; Experimental technology; Health protection and dosimetry; Hydrologic and geologic science; Marine sciences; Materials science; Nuclear science and engineering; Process science and engineering; Sociotechnical systems analysis; Statistics and applied mathematics; and Thermal and energy systems.

  9. Air Force Research Laboratory’s 2006 Technology Milestones

    Science.gov (United States)

    2006-01-01

    tool’s additional features, such as its integration with COMET wizards , facilitate automation of the many steps constituting the analysis checklist...CEASE will enhance space radiation climatology and specification/forecast models. Its representations will lead to more realistic requirements for...Adaptive Optics at the University of Arizona. To obtain the image, researchers used the multimirror telescope natural guide star adaptive optics

  10. Drastic reformation of Electrical and Electronics Engineering Laboratory(Researches)

    OpenAIRE

    青柳, 稔; Minoru, Aoyagi

    2016-01-01

    The Department of Electrical and Electronic Engineering opened in 1978, as the Department of Electrical Engineering. In 1987, the Department of Electrical Engineering was renamed the Department of Electrical and Electronic Engineering. The Department of Electrical and Electronic Engineering has conducted basic educations and studies on electric and electronic engineering. In this paper, I will introduce an overview of recent researches and educations of the Department of Ele ctrical and Elect...

  11. U.S. Army Research Laboratory 2010 Annual Review

    Science.gov (United States)

    2010-12-01

    erICkSonkIrk President Phoenix Engineering Associates, Inc . Peter M. koGGe Professor of Computer Science and Engineering Concurrent Professor of...n t O p e r a t io n s ARL sponsored basic research discoveries in catalysis and nanomaterials at Kansas State University led to the creation of...useful interim report, which has attracted interest beyond ARL in the deliberate pursuit of aligned, parallel data in tandem with the

  12. Composite Patient Reports: A Laboratory Informatics Perspective and Pilot Project for Personalized Medicine and Translational Research

    OpenAIRE

    Gundlapalli, Adi V.; Delgado, Julio C.; Jackson, Brian R.; Tricot, Guido J.; Hill, Harry R.

    2009-01-01

    Clinical laboratories are a strong and integral partner in personalized health care. Laboratory information systems hold a vast amount of data representing human phenotypes, genotypes, biomarkers, progression of disease and response to therapy. These structured and unstructured free text data are critical for patient care and a resource for personalized medicine and translational research. Laboratory data are integrated into many electronic medical records that provide “summary reports” and “...

  13. Laboratory Challenges Conducting International Clinical Research in Resource-Limited Settings

    Science.gov (United States)

    Fitzgibbon, Joseph E.; Wallis, Carole L.

    2014-01-01

    There are many challenges to performing clinical research in resource-limited settings (RLS). Here we discuss several of the most common laboratory issues that must be addressed. These include issues relating to organization and personnel, laboratory facilities and equipment, standard operating procedures, external quality assurance, shipping, laboratory capacity and data management. While much progress has been made, innovative ways of addressing some of these issues are still very much needed. PMID:24321984

  14. Image quality, meteorological optical range, and fog particulate number evaluation using the Sandia National Laboratories fog chamber

    Science.gov (United States)

    Birch, Gabriel C.; Woo, Bryana L.; Sanchez, Andres L.; Knapp, Haley

    2017-08-01

    The evaluation of optical system performance in fog conditions typically requires field testing. This can be challenging due to the unpredictable nature of fog generation and the temporal and spatial nonuniformity of the phenomenon itself. We describe the Sandia National Laboratories fog chamber, a new test facility that enables the repeatable generation of fog within a 55 m×3 m×3 m (L×W×H) environment, and demonstrate the fog chamber through a series of optical tests. These tests are performed to evaluate system image quality, determine meteorological optical range (MOR), and measure the number of particles in the atmosphere. Relationships between typical optical quality metrics, MOR values, and total number of fog particles are described using the data obtained from the fog chamber and repeated over a series of three tests.

  15. ORNLs Laboratory Directed Research and Development Program FY 2008 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2009-03-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2008. The associated FY 2008 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and an internal evaluation of the program’s management process.

  16. ORNLs Laboratory Directed Research and Development Program FY 2013 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2014-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2013. The associated FY 2013 ORNL LDRD Self-Assessment (ORNL/PPA-2014/2) provides financial data and an internal evaluation of the program’s management process.

  17. ORNLs Laboratory Directed Research and Development Program FY 2012 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2013-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2012. The associated FY 2012 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial data and an internal evaluation of the program’s management process.

  18. ORNLs Laboratory Directed Research and Development Program FY 2009 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2010-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2009. The associated FY 2009 ORNL LDRD Self-Assessment (ORNL/PPA-2010/2) provides financial data and an internal evaluation of the program’s management process.

  19. ORNLs Laboratory Directed Research and Development Program FY 2010 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2011-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2010. The associated FY 2010 ORNL LDRD Self-Assessment (ORNL/PPA-2011/2) provides financial data and an internal evaluation of the program’s management process.

  20. ORNLs Laboratory Directed Research and Development Program FY 2011 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2012-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2011. The associated FY 2011 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial data and an internal evaluation of the program’s management process.

  1. Occurrence and identification of hemotropic mycoplasmas (Hemoplasmas) in free ranging and laboratory rats (Rattus norvegicus) from two Brazilian zoos.

    Science.gov (United States)

    Conrado, Francisco de Oliveira; do Nascimento, Naíla Cannes; dos Santos, Andrea Pires; Zimpel, Cristina Kraemer; Messick, Joanne Belle; Biondo, Alexander Welker

    2015-11-23

    Hemotropic mycoplasmas (hemoplasmas), bacteria belonging to the class Mollicutes, are obligatory red blood cell pathogens of a variety of animal species. They may cause acute anemia that is life-threatening or chronic disease that is clinically silent, but may interfere with results of experimental studies when using infected animals. Since these bacteria cannot be cultivated, molecular techniques are the gold standard for diagnosing an infection, investigating its prevalence, and describing new species. Mycoplasma coccoides and M. haemomuris are the most commonly recognized hemoplasmas in the blood of wild and laboratory rodents. Neither the epidemiology nor clinical and molecular characterization of hemoplasma infection in free-ranging rodents in Brazil has been previously reported. The aims of this study were to investigate the occurrence of hemoplasmas in free-ranging rats (Rattus norvegicus) captured in the Passeio Público and Curitiba Zoo and compare hematologic parameters of infected and non-infected animals. Anti-coagulated blood samples collected from 43 free-ranging and 20 nursery rats were included in the study. Overall 63.5% were positive using SYBR® Green quantitative PCR (qPCR) of the 16S rRNA gene to screen for hemoplasma infection (72% among free-ranging rats; 45% among laboratory-raised rats). Sequencing of the qPCR products showed that all but one sample had >98% identity to M. haemomuris. Phylogenetic analysis based on a fragment of approximately 1300 bp of the 16S rRNA gene showed 99% identity to a new hemoplasma from European rats and 98% identity to a hemotropic mycoplasma described infecting a European harvest mouse (Micromys minutus). No statistically significant changes in hematologic parameters between infected and non-infected rats were found, confirming the low pathogenicity and/or silent characteristics of the infection. Our findings suggest that hemoplasmas are likely endemic in rodent species in this region. The epidemiology

  2. Open Air Laboratories (OPAL): a community-driven research programme.

    Science.gov (United States)

    Davies, L; Bell, J N B; Bone, J; Head, M; Hill, L; Howard, C; Hobbs, S J; Jones, D T; Power, S A; Rose, N; Ryder, C; Seed, L; Stevens, G; Toumi, R; Voulvoulis, N; White, P C L

    2011-01-01

    OPAL is an English national programme that takes scientists into the community to investigate environmental issues. Biological monitoring plays a pivotal role covering topics of: i) soil and earthworms; ii) air, lichens and tar spot on sycamore; iii) water and aquatic invertebrates; iv) biodiversity and hedgerows; v) climate, clouds and thermal comfort. Each survey has been developed by an inter-disciplinary team and tested by voluntary, statutory and community sectors. Data are submitted via the web and instantly mapped. Preliminary results are presented, together with a discussion on data quality and uncertainty. Communities also investigate local pollution issues, ranging from nitrogen deposition on heathlands to traffic emissions on roadside vegetation. Over 200,000 people have participated so far, including over 1000 schools and 1000 voluntary groups. Benefits include a substantial, growing database on biodiversity and habitat condition, much from previously unsampled sites particularly in urban areas, and a more engaged public. Copyright © 2011 Elsevier Ltd. All rights reserved.

  3. Surveys of research in the Chemistry Division, Argonne National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Grazis, B.M. [ed.

    1992-11-01

    Research reports are presented on reactive intermediates in condensed phase (radiation chemistry, photochemistry), electron transfer and energy conversion, photosynthesis and solar energy conversion, metal cluster chemistry, chemical dynamics in gas phase, photoionization-photoelectrons, characterization and reactivity of coal and coal macerals, premium coal sample program, chemical separations, heavy elements coordination chemistry, heavy elements photophysics/photochemistry, f-electron interactions, radiation chemistry of high-level wastes (gas generation in waste tanks), ultrafast molecular electronic devices, and nuclear medicine. Separate abstracts have been prepared. Accelerator activites and computer system/network services are also reported.

  4. Surveys of research in the Chemistry Division, Argonne National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Grazis, B.M. (ed.)

    1992-01-01

    Research reports are presented on reactive intermediates in condensed phase (radiation chemistry, photochemistry), electron transfer and energy conversion, photosynthesis and solar energy conversion, metal cluster chemistry, chemical dynamics in gas phase, photoionization-photoelectrons, characterization and reactivity of coal and coal macerals, premium coal sample program, chemical separations, heavy elements coordination chemistry, heavy elements photophysics/photochemistry, f-electron interactions, radiation chemistry of high-level wastes (gas generation in waste tanks), ultrafast molecular electronic devices, and nuclear medicine. Separate abstracts have been prepared. Accelerator activites and computer system/network services are also reported.

  5. The GATO gene annotation tool for research laboratories.

    Science.gov (United States)

    Fujita, A; Massirer, K B; Durham, A M; Ferreira, C E; Sogayar, M C

    2005-11-01

    Large-scale genome projects have generated a rapidly increasing number of DNA sequences. Therefore, development of computational methods to rapidly analyze these sequences is essential for progress in genomic research. Here we present an automatic annotation system for preliminary analysis of DNA sequences. The gene annotation tool (GATO) is a Bioinformatics pipeline designed to facilitate routine functional annotation and easy access to annotated genes. It was designed in view of the frequent need of genomic researchers to access data pertaining to a common set of genes. In the GATO system, annotation is generated by querying some of the Web-accessible resources and the information is stored in a local database, which keeps a record of all previous annotation results. GATO may be accessed from everywhere through the internet or may be run locally if a large number of sequences are going to be annotated. It is implemented in PHP and Perl and may be run on any suitable Web server. Usually, installation and application of annotation systems require experience and are time consuming, but GATO is simple and practical, allowing anyone with basic skills in informatics to access it without any special training. GATO can be downloaded at [http://mariwork.iq.usp.br/gato/]. Minimum computer free space required is 2 MB.

  6. The GATO gene annotation tool for research laboratories

    Directory of Open Access Journals (Sweden)

    A. Fujita

    2005-11-01

    Full Text Available Large-scale genome projects have generated a rapidly increasing number of DNA sequences. Therefore, development of computational methods to rapidly analyze these sequences is essential for progress in genomic research. Here we present an automatic annotation system for preliminary analysis of DNA sequences. The gene annotation tool (GATO is a Bioinformatics pipeline designed to facilitate routine functional annotation and easy access to annotated genes. It was designed in view of the frequent need of genomic researchers to access data pertaining to a common set of genes. In the GATO system, annotation is generated by querying some of the Web-accessible resources and the information is stored in a local database, which keeps a record of all previous annotation results. GATO may be accessed from everywhere through the internet or may be run locally if a large number of sequences are going to be annotated. It is implemented in PHP and Perl and may be run on any suitable Web server. Usually, installation and application of annotation systems require experience and are time consuming, but GATO is simple and practical, allowing anyone with basic skills in informatics to access it without any special training. GATO can be downloaded at [http://mariwork.iq.usp.br/gato/]. Minimum computer free space required is 2 MB.

  7. Writing Material in Chemical Physics Research: The Laboratory Notebook as Locus of Technical and Textual Integration

    Science.gov (United States)

    Wickman, Chad

    2010-01-01

    This article, drawing on ethnographic study in a chemical physics research facility, explores how notebooks are used and produced in the conduct of laboratory science. Data include written field notes of laboratory activity; visual documentation of "in situ" writing processes; analysis of inscriptions, texts, and material artifacts produced in the…

  8. Testing painted wood : past practices at the Forest Products Laboratory and recommendations for future research

    Science.gov (United States)

    R. Sam Williams

    2009-01-01

    A brief history of paint research at the Forest Products Laboratory (FPL) in Madison, Wisconsin, sets the stage for a discussion of testing paint on wood and wood products. Tests include laboratory and outdoor tests, and I discuss them in terms of several degradation mechanisms (loss of gloss and fading, mildew growth, extractives bleed, and cracking, flaking, and...

  9. Developing Digital Courseware for a Virtual Nano-Biotechnology Laboratory: A Design-Based Research Approach

    Science.gov (United States)

    Yueh, Hsiu-Ping; Chen, Tzy-Ling; Lin, Weijane; Sheen, Horn-Jiunn

    2014-01-01

    This paper first reviews applications of multimedia in engineering education, especially in laboratory learning. It then illustrates a model and accreditation criteria adopted for developing a specific set of nanotechnology laboratory courseware and reports the design-based research approach used in designing and developing the e-learning…

  10. Hairy Root as a Model System for Undergraduate Laboratory Curriculum and Research

    Science.gov (United States)

    Keyes, Carol A.; Subramanian, Senthil; Yu, Oliver

    2009-01-01

    Hairy root transformation has been widely adapted in plant laboratories to rapidly generate transgenic roots for biochemical and molecular analysis. We present hairy root transformations as a versatile and adaptable model system for a wide variety of undergraduate laboratory courses and research. This technique is easy, efficient, and fast making…

  11. Mapping Maize Genes: A Series of Research-Based Laboratory Exercises

    Science.gov (United States)

    Makarevitch, Irina; Kralich, Elizabeth

    2011-01-01

    Open-ended, inquiry-based multiweek laboratory exercises are the key elements to increasing students' understanding and retention of the major biological concepts. Including original research into undergraduate teaching laboratories has also been shown to motivate students and improve their learning. Here, we present a series of original…

  12. Government-industry-uUniversity and rResearch lLaboratories cCoordination for new product development: Session 2. Government research laboratory perspective

    Energy Technology Data Exchange (ETDEWEB)

    Kuzay, T.M.

    1997-09-01

    This talk is the second in an expanded series of presentations on the Government-Industry-University and Research Laboratories Coordination for new product development, which is a timely and important public policy issue. Such interactions have become particularly timely in light of the present decline in funding for research and development (R&D) in the nation`s budget and in the private sector. These interactions, at least in principle, provide a means to maximize benefits for the greater good of the nation by pooling the diminishing resources. National laboratories, which traditionally interacted closely with the universities in educational training, now are able to also participate closely with industry in joint R&D thanks to a number of public laws legislated since the early 80s. A review of the experiences with such interactions at Argonne National Laboratory, which exemplifies the national laboratories, shows that, despite differences in their traditions and the missions, the national laboratory-industry-university triangle can work together.

  13. Idaho National Laboratory Experimental Research In High Temperature Electrolysis For Hydrogen And Syngas Production

    Energy Technology Data Exchange (ETDEWEB)

    Carl M. Stoots; James E. O' Brien; J. Stephen Herring; Joseph J. Hartvigsen

    2008-09-01

    The Idaho National Laboratory (Idaho Falls, Idaho, USA), in collaboration with Ceramatec, Inc. (Salt Lake City, Utah, USA), is actively researching the application of solid oxide fuel cell technology as electrolyzers for large scale hydrogen and syngas production. This technology relies upon electricity and high temperature heat to chemically reduce a steam or steam / CO2 feedstock. Single button cell tests, multi-cell stack, as well as multi-stack testing has been conducted. Stack testing used 10 x 10 cm cells (8 x 8 cm active area) supplied by Ceramatec and ranged from 10 cell short stacks to 240 cell modules. Tests were conducted either in a bench-scale test apparatus or in a newly developed 5 kW Integrated Laboratory Scale (ILS) test facility. Gas composition, operating voltage, and operating temperature were varied during testing. The tests were heavily instrumented, and outlet gas compositions were monitored with a gas chromatograph. The ILS facility is currently being expanded to ~15 kW testing capacity (H2 production rate based upon lower heating value).

  14. A guide to research facilities at the National Renewable Energy Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The guide is divided into two parts. Topping the pages are descriptions of laboratories at NREL that provide sophisticated experimental equipment, testing capabilities, or processes that may not be available in the private sector. Scientific categories are designated at the top of the pages in blue; individual laboratory descriptions follow alphabetically, along with the names and phone numbers of the laboratory managers. In blue boxes at the bottom of the pages are articles about NREL, our technology transfer program, and our facilities, as well as guidelines for students, researchers, and industrial collaborators who wish to use them. A list of key contacts and a map of the campus follows the laboratory descriptions.

  15. Characterization of research conducted at the Research Laboratory of the KOMAG Mining Mechanization Center

    Energy Technology Data Exchange (ETDEWEB)

    Tomanek, B. (Centrum Mechanizacji Gornictwa KOMAG (Poland))

    1992-07-01

    Describes the potential of the CMG KOMAG Laboratory in Mikolow (Poland) in the field of chemical and metallographic investigations. The Laboratory can conduct complete chemical analyses of steel, cast iron, copper, aluminium and their alloys. The mechanical properties and the macro- and micro-structure of metals can be investigated. Types of tests and investigations conducted at the Laboratory are named. The testing equipment at its disposal is described (e.g. the E983 spectrometer, microscopes, the Micro-Durometer 4000). The Laboratory is poised to obtain accreditation by the European Organization of Quality (EOQ).

  16. Laboratory Directed Research & Development Program. Annual report to the Department of Energy, Revised December 1993

    Energy Technology Data Exchange (ETDEWEB)

    Ogeka, G.J.; Romano, A.J.

    1993-12-01

    At Brookhaven National Laboratory the Laboratory Directed Research and Development (LDRD) Program is a discretionary research and development tool critical in maintaining the scientific excellence and vitality of the laboratory. It is also a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor in achieving and maintaining staff excellence, and a means to address national needs, within the overall mission of the Department of Energy and Brookhaven National Laboratory. This report summarizes research which was funded by this program during fiscal year 1993. The research fell in a number of broad technical and scientific categories: new directions for energy technologies; global change; radiation therapies and imaging; genetic studies; new directions for the development and utilization of BNL facilities; miscellaneous projects. Two million dollars in funding supported 28 projects which were spread throughout all BNL scientific departments.

  17. Laptops in Psychology: Conducting Flexible In-Class Research and Writing Laboratories

    Science.gov (United States)

    Stephens, Benjamin R.

    2005-01-01

    This chapter describes an undergraduate psychology research methods course in which laptops facilitated online organization, electronic portfolios, and flexible laboratories to improve student engagement, capability, and understanding. (Contains 3 figures.)

  18. Laboratory Directed Research and Development Program. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    Ogeka, G.J.; Romano, A.J.

    1992-12-01

    This report briefly discusses the following research: Advances in Geoexploration; Transvenous Coronary Angiography with Synchrotron X-Rays; Borehole Measurements of Global Warming; Molecular Ecology: Development of Field Methods for Microbial Growth Rate and Activity Measurements; A New Malaria Enzyme - A Potential Source for a New Diagnostic Test for Malaria and a Target for a New Antimalarial Drug; Basic Studies on Thoron and Thoron Precursors; Cloning of the cDNA for a Human Serine/Threonine Protein Kinase that is Activated Specifically by Double-Stranded DNA; Development of an Ultra-Fast Laser System for Accelerator Applications; Cluster Impact Fusion; Effect of a Bacterial Spore Protein on Mutagenesis; Structure and Function of Adenovirus Penton Base Protein; High Resolution Fast X-Ray Detector; Coherent Synchrotron Radiation Longitudinal Bunch Shape Monitor; High Grain Harmonic Generation Experiment; BNL Maglev Studies; Structural Investigations of Pt-Based Catalysts; Studies on the Cellular Toxicity of Cocaine and Cocaethylene; Human Melanocyte Transformation; Exploratory Applications of X-Ray Microscopy; Determination of the Higher Ordered Structure of Eukaryotic Chromosomes; Uranium Neutron Capture Therapy; Tunneling Microscopy Studies of Nanoscale Structures; Nuclear Techiques for Study of Biological Channels; RF Sources for Accelerator Physics; Induction and Repair of Double-Strand Breaks in the DNA of Human Lymphocytes; and An EBIS Source of High Charge State Ions up to Uranium.

  19. Ethical and methodological standards for laboratory and medical biological rhythm research.

    Science.gov (United States)

    Portaluppi, Francesco; Touitou, Yvan; Smolensky, Michael H

    2008-11-01

    The main objectives of this article are to update the ethical standards for the conduct of human and animal biological rhythm research and recommend essential elements for quality chronobiological research information, which should be especially useful for new investigators of the rhythms of life. A secondary objective is to provide for those with an interest in the results of chronobiology investigations, but who might be unfamiliar with the field, an introduction to the basic methods and standards of biological rhythm research and time series data analysis. The journal and its editors endorse compliance of all investigators to the principles of the Declaration of Helsinki of the World Medical Association, which relate to the conduct of ethical research on human beings, and the Guide for the Care and Use of Laboratory Animals of the Institute for Laboratory Animal Research of the National Research Council, which relate to the conduct of ethical research on laboratory and other animals. The editors and the readers of the journal expect the authors of submitted manuscripts to have adhered to the ethical standards dictated by local, national, and international laws and regulations in the conduct of investigations and to be unbiased and accurate in reporting never-before-published research findings. Authors of scientific papers are required to disclose all potential conflicts of interest, particularly when the research is funded in part or in full by the medical and pharmaceutical industry, when the authors are stock-holders of the company that manufactures or markets the products under study, or when the authors are a recent or current paid consultant to the involved company. It is the responsibility of the authors of submitted manuscripts to clearly present sufficient detail about the synchronizer schedule of the studied subjects (i.e., the sleep-wake schedule, ambient light-dark cycle, intensity and spectrum of ambient light exposure, seasons when the research was

  20. Research on insect pests of tree fruits at the USDA-ARS laboratory in Wapato, WA

    Science.gov (United States)

    Tree fruit-related entomological research currently being conducted at the USDA-ARS laboratory in Wapato, WA is reviewed. Scientists at the United States Department of Agriculture, Agricultural Research Service (USDA-ARS) in Wapato, WA conduct research on insect pests of tree fruits and potato. Th...

  1. Chronicle of 65 years of wood finishing research at the Forest Products Laboratory

    Science.gov (United States)

    Thomas M. Gorman; William C. Feist

    1989-01-01

    For 65 years, the Forest Products Laboratory (FPL) in Madison, Wisconsin, has had a continuous and extensive program of research on finishing wood for outdoor use. The research has stressed the fundamental aspects of wood weathering and the interactions of pretreatments and finishes on wood surfaces. This report outlines the history of the FPL wood finishing research...

  2. Development and Assessment of Green, Research-Based Instructional Materials for the General Chemistry Laboratory

    Science.gov (United States)

    Cacciatore, Kristen L.

    2010-01-01

    This research entails integrating two novel approaches for enriching student learning in chemistry into the context of the general chemistry laboratory. The first is a pedagogical approach based on research in cognitive science and the second is the green chemistry philosophy. Research has shown that inquiry-based approaches are effective in…

  3. University of Illinois at Urbana-Champaign, Materials Research Laboratory progress report for FY 1992

    Energy Technology Data Exchange (ETDEWEB)

    1992-07-01

    This interdisciplinary laboratory in the College of Engineering support research in areas of condensed matter physics, solid state chemistry, and materials science. These research programs are developed with the assistance of faculty, students, and research associates in the departments of Physics, Materials Science and Engineering, chemistry, Chemical Engineering, Electrical Engineering, Mechanical Engineering, and Nuclear Engineering.

  4. Applied human factors research at the NASA Johnson Space Center Human-Computer Interaction Laboratory

    Science.gov (United States)

    Rudisill, Marianne; Mckay, Timothy D.

    1990-01-01

    The applied human factors research program performed at the NASA Johnson Space Center's Human-Computer Interaction Laboratory is discussed. Research is conducted to advance knowledge in human interaction with computer systems during space crew tasks. In addition, the Laboratory is directly involved in the specification of the human-computer interface (HCI) for space systems in development (e.g., Space Station Freedom) and is providing guidelines and support for HCI design to current and future space missions.

  5. US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview

    Science.gov (United States)

    2017-11-01

    5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) US Army Research Laboratory Sensors and Electron...Devices Directorate (ATTN: RDRL-SER-W) 2800 Powder Mill Road Adelphi, MD 20783-1138 8. PERFORMING ORGANIZATION REPORT NUMBER ARL-TR-8199 9...sensor and transmitter architecture was developed in support of an ongoing collaborative agreement between the US Army Research Laboratory (ARL) and the

  6. The evolution of drug design at Merck Research Laboratories

    Science.gov (United States)

    Brown, Frank K.; Sherer, Edward C.; Johnson, Scott A.; Holloway, M. Katharine; Sherborne, Bradley S.

    2017-03-01

    On October 5, 1981, Fortune magazine published a cover article entitled the "Next Industrial Revolution: Designing Drugs by Computer at Merck". With a 40+ year investment, we have been in the drug design business longer than most. During its history, the Merck drug design group has had several names, but it has always been in the "design" business, with the ultimate goal to provide an actionable hypothesis that could be tested experimentally. Often the result was a small molecule but it could just as easily be a peptide, biologic, predictive model, reaction, process, etc. To this end, the concept of design is now front and center in all aspects of discovery, safety assessment and early clinical development. At present, the Merck design group includes computational chemistry, protein structure determination, and cheminformatics. By bringing these groups together under one umbrella, we were able to align activities and capabilities across multiple research sites and departments. This alignment from 2010 to 2016 resulted in an 80% expansion in the size of the department, reflecting the increase in impact due to a significant emphasis across the organization to "design first" along the entire drug discovery path from lead identification (LID) to first in human (FIH) dosing. One of the major advantages of this alignment has been the ability to access all of the data and create an adaptive approach to the overall LID to FIH pathway for any modality, significantly increasing the quality of candidates and their probability of success. In this perspective, we will discuss how we crafted a new strategy, defined the appropriate phenotype for group members, developed the right skillsets, and identified metrics for success in order to drive continuous improvement. We will not focus on the tactical implementation, only giving specific examples as appropriate.

  7. The evolution of drug design at Merck Research Laboratories.

    Science.gov (United States)

    Brown, Frank K; Sherer, Edward C; Johnson, Scott A; Holloway, M Katharine; Sherborne, Bradley S

    2017-03-01

    On October 5, 1981, Fortune magazine published a cover article entitled the "Next Industrial Revolution: Designing Drugs by Computer at Merck". With a 40+ year investment, we have been in the drug design business longer than most. During its history, the Merck drug design group has had several names, but it has always been in the "design" business, with the ultimate goal to provide an actionable hypothesis that could be tested experimentally. Often the result was a small molecule but it could just as easily be a peptide, biologic, predictive model, reaction, process, etc. To this end, the concept of design is now front and center in all aspects of discovery, safety assessment and early clinical development. At present, the Merck design group includes computational chemistry, protein structure determination, and cheminformatics. By bringing these groups together under one umbrella, we were able to align activities and capabilities across multiple research sites and departments. This alignment from 2010 to 2016 resulted in an 80% expansion in the size of the department, reflecting the increase in impact due to a significant emphasis across the organization to "design first" along the entire drug discovery path from lead identification (LID) to first in human (FIH) dosing. One of the major advantages of this alignment has been the ability to access all of the data and create an adaptive approach to the overall LID to FIH pathway for any modality, significantly increasing the quality of candidates and their probability of success. In this perspective, we will discuss how we crafted a new strategy, defined the appropriate phenotype for group members, developed the right skillsets, and identified metrics for success in order to drive continuous improvement. We will not focus on the tactical implementation, only giving specific examples as appropriate.

  8. Using Calculator-Based Laboratory Technology to Conduct Undergraduate Chemical Research

    Science.gov (United States)

    Sales, Cynthia L.; Ragan, Nicole M.; Kendrick Murphy, Maureen

    2001-05-01

    Calculator-based laboratory (CBL) technology can be used to initiate a viable undergraduate research program and at the same time teach ethical behavior in science and research. One research project, utilizing buckminsterfullerene, is described as a prototype of the quality and scope of such chemical research programs. Eight original research project ideas are presented for undergraduates to pursue using readily available materials and pH, colorimeter, relative humidity, temperature, light, carbon dioxide, and dissolved oxygen probes. See Letter re: this article.

  9. [Research progress in the structure and fuction of Orthopoxvirus host range genes].

    Science.gov (United States)

    Liu, Zheng; Liu, Ying; Shao, Yi-Ming

    2013-06-01

    Orthopoxvirus vector has a broad prospect in recombinant vaccine research, but the rarely severe side-effect impedes its development. Vaccinia virus and Cowpox virus of Orthopoxvirus have broad host range, and they have typical host range genes as K1L, CP77 and C7L. These three genes affect host range of Vaccinia virus, disturb the cell signaling pathways, suppress immune response and are related to virulence.

  10. The Colorado Front Range Ecosystem Management Research Project: Accomplishments to date

    Science.gov (United States)

    Brian Kent; Wayne D. Shepperd; Deborah J. Shields

    2000-01-01

    This article briefly describes the goals and objectives for the Colorado Front Range Ecosystem Management Project (FREM). Research under this project has addressed both biophysical and human dimensions problems relating to ecosystem management in the Colorado Front Range. Results of completed work are described, and the status of the ongoing demonstration project at...

  11. LABORATORY DIRECTED RESEARCH AND DEVELOPMENT ANNUAL REPORT TO THE DEPARTMENT OF ENERGY - DECEMBER 2006

    Energy Technology Data Exchange (ETDEWEB)

    FOX, K.J.

    2006-12-31

    Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's total annual budget has averaged about $460 million. There are about 2,500 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, ''Laboratory Directed Research and Development,'' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy National Nuclear Security Administration Laboratories dated June 13, 2006. In accordance this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2006.

  12. LDRD 2013 Annual Report: Laboratory Directed Research and Development Program Activities

    Energy Technology Data Exchange (ETDEWEB)

    Bookless, W. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2013-12-31

    This LDRD project establishes a research program led by Jingguang Chen, who has started a new position as a Joint Appointee between BNL and Columbia University as of FY2013. Under this project, Dr. Chen will establish a new program in catalysis science at BNL and Columbia University. The LDRD program will provide initial research funding to start research at both BNL and Columbia. At BNL, Dr. Chen will initiate laboratory research, including hiring research staff, and will collaborate with the existing BNL catalysis and electrocatalysis research groups. At Columbia, a subcontract to Dr. Chen will provide startup funding for his laboratory research, including initial graduate student costs. The research efforts will be linked under a common Catalysis Program in Sustainable Fuels. The overall impact of this project will be to strengthen the BNL catalysis science program through new linked research thrusts and the addition of an internationally distinguished catalysis scientist.

  13. The Advanced Interdisciplinary Research Laboratory: A Student Team Approach to the Fourth-Year Research Thesis Project Experience

    Science.gov (United States)

    Piunno, Paul A. E.; Boyd, Cleo; Barzda, Virginijus; Gradinaru, Claudiu C.; Krull, Ulrich J.; Stefanovic, Sasa; Stewart, Bryan

    2014-01-01

    The advanced interdisciplinary research laboratory (AIRLab) represents a novel, effective, and motivational course designed from the interdisciplinary research interests of chemistry, physics, biology, and education development faculty members as an alternative to the independent thesis project experience. Student teams are assembled to work…

  14. Through Microgravity and Towards the Stars: Microgravity and Strategic Research at Marshall's Biological and Physical Space Research Laboratory

    Science.gov (United States)

    Curreri, Peter A.

    2003-01-01

    The Microgravity and Strategic research at Marshall s Biological and Physical Space Research Laboratory will be reviewed. The environment in orbit provides a unique opportunity to study Materials Science and Biotechnology in the absence of sedimentation and convection. There are a number of peer-selected investigations that have been selected to fly on the Space Station that have been conceived and are led by Marshall s Biological and Physical Research Laboratory s scientists. In addition to Microgravity research the Station will enable research in "Strategic" Research Areas that focus on enabling humans to live, work, and explore the solar system safely. New research in Radiation Protection, Strategic Molecular Biology, and In-Space Fabrication will be introduced.

  15. Accelerating Ocean Energy to the Marketplace – Environmental Research at the U.S. Department of Energy National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Copping, Andrea E.; Cada, G. F.; Roberts, Jesse; Bevelhimer, Mark

    2010-10-06

    The U.S. Department of Energy (US DOE) has mobilized its National Laboratories to address the broad range of environmental effects of ocean and river energy development. The National Laboratories are using a risk-based approach to set priorities among environmental effects, and to direct research activities. Case studies will be constructed to determine the most significant environmental effects of ocean energy harvest for tidal systems in temperate estuaries, for wave energy installations in temperate coastal areas, wave installations in sub-tropical waters, and riverine energy installations in large rivers. In addition, the National Laboratories are investigating the effects of energy removal from waves, tides and river currents using numerical modeling studies. Laboratory and field research is also underway to understand the effects of electromagnetic fields (EMF), acoustic noise, toxicity from anti-biofouling coatings, effects on benthic habitats, and physical interactions with tidal and wave devices on marine and freshwater organisms and ecosystems. Outreach and interactions with stakeholders allow the National Laboratories to understand and mitigate for use conflicts and to provide useful information for marine spatial planning at the national and regional level.

  16. Perspective on One Decade of Laser Propulsion Research at Air Force Research Laboratory

    Science.gov (United States)

    Larson, C. William

    2008-04-01

    The Air Force Laser Propulsion Program spanned nearly 10-years and included about 35-weeks of experimental research with the Pulsed Laser Vulnerability Test System of the High Energy Laser Systems Test Facility at White Sands Missile Range, New Mexico, WSMR/HELSTF/PLVTS. PLVTS is a pulsed CO2 laser that produces up to 10 kW of power in ˜10 cm2 spot at wavelength of 10.6 microns. The laser is capable of a pulse repetition rate up to 25 Hz, with pulse durations of about 20 microseconds. During the program basic research was conducted on the production of propulsion thrust from laser energy through heating of air and ablation of various candidate rocket propellant fuels. Flight tests with an ablation fuel (Delrin) and air were accomplished with a model Laser Lightcraft vehicle that was optimized for propulsion by the PLVTS at its maximum power output, 10 kW at 25 Hz, 400 J/pulse. Altitudes exceeding 200-feet were achieved with ablation fuels. The most recent contributions to the technology included development of a mini-thruster standard for testing of chemically enhanced fuels and theoretical calculations on the performance of formulations containing ammonium nitrate and Delrin. Results of these calculations will also be reported here.

  17. Developing a Collaborative Agenda for Humanities and Social Scientific Research on Laboratory Animal Science and Welfare

    Science.gov (United States)

    Davies, Gail F.; Greenhough, Beth J; Hobson-West, Pru; Kirk, Robert G. W.; Applebee, Ken; Bellingan, Laura C.; Berdoy, Manuel; Buller, Henry; Cassaday, Helen J.; Davies, Keith; Diefenbacher, Daniela; Druglitrø, Tone; Escobar, Maria Paula; Friese, Carrie; Herrmann, Kathrin; Hinterberger, Amy; Jarrett, Wendy J.; Jayne, Kimberley; Johnson, Adam M.; Johnson, Elizabeth R.; Konold, Timm; Leach, Matthew C.; Leonelli, Sabina; Lewis, David I.; Lilley, Elliot J.; Longridge, Emma R.; McLeod, Carmen M.; Miele, Mara; Nelson, Nicole C.; Ormandy, Elisabeth H.; Pallett, Helen; Poort, Lonneke; Pound, Pandora; Ramsden, Edmund; Roe, Emma; Scalway, Helen; Schrader, Astrid; Scotton, Chris J.; Scudamore, Cheryl L.; Smith, Jane A.; Whitfield, Lucy; Wolfensohn, Sarah

    2016-01-01

    Improving laboratory animal science and welfare requires both new scientific research and insights from research in the humanities and social sciences. Whilst scientific research provides evidence to replace, reduce and refine procedures involving laboratory animals (the ‘3Rs’), work in the humanities and social sciences can help understand the social, economic and cultural processes that enhance or impede humane ways of knowing and working with laboratory animals. However, communication across these disciplinary perspectives is currently limited, and they design research programmes, generate results, engage users, and seek to influence policy in different ways. To facilitate dialogue and future research at this interface, we convened an interdisciplinary group of 45 life scientists, social scientists, humanities scholars, non-governmental organisations and policy-makers to generate a collaborative research agenda. This drew on methods employed by other agenda-setting exercises in science policy, using a collaborative and deliberative approach for the identification of research priorities. Participants were recruited from across the community, invited to submit research questions and vote on their priorities. They then met at an interactive workshop in the UK, discussed all 136 questions submitted, and collectively defined the 30 most important issues for the group. The output is a collaborative future agenda for research in the humanities and social sciences on laboratory animal science and welfare. The questions indicate a demand for new research in the humanities and social sciences to inform emerging discussions and priorities on the governance and practice of laboratory animal research, including on issues around: international harmonisation, openness and public engagement, ‘cultures of care’, harm-benefit analysis and the future of the 3Rs. The process outlined below underlines the value of interdisciplinary exchange for improving communication across

  18. Developing a Collaborative Agenda for Humanities and Social Scientific Research on Laboratory Animal Science and Welfare.

    Directory of Open Access Journals (Sweden)

    Gail F Davies

    Full Text Available Improving laboratory animal science and welfare requires both new scientific research and insights from research in the humanities and social sciences. Whilst scientific research provides evidence to replace, reduce and refine procedures involving laboratory animals (the '3Rs', work in the humanities and social sciences can help understand the social, economic and cultural processes that enhance or impede humane ways of knowing and working with laboratory animals. However, communication across these disciplinary perspectives is currently limited, and they design research programmes, generate results, engage users, and seek to influence policy in different ways. To facilitate dialogue and future research at this interface, we convened an interdisciplinary group of 45 life scientists, social scientists, humanities scholars, non-governmental organisations and policy-makers to generate a collaborative research agenda. This drew on methods employed by other agenda-setting exercises in science policy, using a collaborative and deliberative approach for the identification of research priorities. Participants were recruited from across the community, invited to submit research questions and vote on their priorities. They then met at an interactive workshop in the UK, discussed all 136 questions submitted, and collectively defined the 30 most important issues for the group. The output is a collaborative future agenda for research in the humanities and social sciences on laboratory animal science and welfare. The questions indicate a demand for new research in the humanities and social sciences to inform emerging discussions and priorities on the governance and practice of laboratory animal research, including on issues around: international harmonisation, openness and public engagement, 'cultures of care', harm-benefit analysis and the future of the 3Rs. The process outlined below underlines the value of interdisciplinary exchange for improving

  19. Developing a Collaborative Agenda for Humanities and Social Scientific Research on Laboratory Animal Science and Welfare.

    Science.gov (United States)

    Davies, Gail F; Greenhough, Beth J; Hobson-West, Pru; Kirk, Robert G W; Applebee, Ken; Bellingan, Laura C; Berdoy, Manuel; Buller, Henry; Cassaday, Helen J; Davies, Keith; Diefenbacher, Daniela; Druglitrø, Tone; Escobar, Maria Paula; Friese, Carrie; Herrmann, Kathrin; Hinterberger, Amy; Jarrett, Wendy J; Jayne, Kimberley; Johnson, Adam M; Johnson, Elizabeth R; Konold, Timm; Leach, Matthew C; Leonelli, Sabina; Lewis, David I; Lilley, Elliot J; Longridge, Emma R; McLeod, Carmen M; Miele, Mara; Nelson, Nicole C; Ormandy, Elisabeth H; Pallett, Helen; Poort, Lonneke; Pound, Pandora; Ramsden, Edmund; Roe, Emma; Scalway, Helen; Schrader, Astrid; Scotton, Chris J; Scudamore, Cheryl L; Smith, Jane A; Whitfield, Lucy; Wolfensohn, Sarah

    2016-01-01

    Improving laboratory animal science and welfare requires both new scientific research and insights from research in the humanities and social sciences. Whilst scientific research provides evidence to replace, reduce and refine procedures involving laboratory animals (the '3Rs'), work in the humanities and social sciences can help understand the social, economic and cultural processes that enhance or impede humane ways of knowing and working with laboratory animals. However, communication across these disciplinary perspectives is currently limited, and they design research programmes, generate results, engage users, and seek to influence policy in different ways. To facilitate dialogue and future research at this interface, we convened an interdisciplinary group of 45 life scientists, social scientists, humanities scholars, non-governmental organisations and policy-makers to generate a collaborative research agenda. This drew on methods employed by other agenda-setting exercises in science policy, using a collaborative and deliberative approach for the identification of research priorities. Participants were recruited from across the community, invited to submit research questions and vote on their priorities. They then met at an interactive workshop in the UK, discussed all 136 questions submitted, and collectively defined the 30 most important issues for the group. The output is a collaborative future agenda for research in the humanities and social sciences on laboratory animal science and welfare. The questions indicate a demand for new research in the humanities and social sciences to inform emerging discussions and priorities on the governance and practice of laboratory animal research, including on issues around: international harmonisation, openness and public engagement, 'cultures of care', harm-benefit analysis and the future of the 3Rs. The process outlined below underlines the value of interdisciplinary exchange for improving communication across

  20. Leopard (Panthera pardus status, distribution, and the research efforts across its range

    Directory of Open Access Journals (Sweden)

    Andrew P. Jacobson

    2016-05-01

    Full Text Available The leopard’s (Panthera pardus broad geographic range, remarkable adaptability, and secretive nature have contributed to a misconception that this species might not be severely threatened across its range. We find that not only are several subspecies and regional populations critically endangered but also the overall range loss is greater than the average for terrestrial large carnivores. To assess the leopard’s status, we compile 6,000 records at 2,500 locations from over 1,300 sources on its historic (post 1750 and current distribution. We map the species across Africa and Asia, delineating areas where the species is confirmed present, is possibly present, is possibly extinct or is almost certainly extinct. The leopard now occupies 25–37% of its historic range, but this obscures important differences between subspecies. Of the nine recognized subspecies, three (P. p. pardus, fusca, and saxicolor account for 97% of the leopard’s extant range while another three (P. p. orientalis, nimr, and japonensis have each lost as much as 98% of their historic range. Isolation, small patch sizes, and few remaining patches further threaten the six subspecies that each have less than 100,000 km2 of extant range. Approximately 17% of extant leopard range is protected, although some endangered subspecies have far less. We found that while leopard research was increasing, research effort was primarily on the subspecies with the most remaining range whereas subspecies that are most in need of urgent attention were neglected.

  1. Recent Research Progress on Non-aqueous Lithium-Air Batteries from Argonne National Laboratory

    Directory of Open Access Journals (Sweden)

    Jun Lu

    2013-11-01

    Full Text Available Rechargeable non-aqueous Li-air battery technology offers potential advantages over other existing battery systems in terms of specific energy and energy density, which could enable the driving range of an electric vehicle to be comparable to that of gasoline vehicles. Development of efficient cathode catalysts and stable electrolytes for the Li-air battery has been intensively investigated for the past several years, and a number of review articles covering different topics are already available. This review mainly focuses on the research activities on rechargeable non-aqueous Li-air batteries at Argonne National Laboratory, with the emphasis on the gains in understanding of electrolyte decomposition, the structure and magnetic properties of lithium peroxide (Li2O2, development of an air-breathing cathode, and the effect of oxygen crossover on the lithium anode. Insights from this research have led to the improvement of the electrochemical performance of Li-air batteries. Promising paths for future work on rechargeable Li-air batteries are also discussed.

  2. Review of Pacific Northwest Laboratory research on aquatic effects of hydroelectric generation and assessment of research needs

    Energy Technology Data Exchange (ETDEWEB)

    Fickeisen, D.H.; Becker, C.D.; Neitzel, D.A.

    1981-05-01

    This report is an overview of Pacific Northwest Laboratory's (PNL) research on how hydroelectric generation affects aquatic biota and environments. The major accomplishments of this research are described, and additional work needed to permit optimal use of available data is identified. The research goals are to: (1) identify impacts of hydroelectric generation, (2) provide guidance in allocating scarce water resources, and (3) develop techniques to avoid or reduce the impacts on aquatic communities or to compensate for unavoidable impacts. Through laboratory and field experiments, an understanding is being developed of the generic impacts of hydrogeneration. Because PNL is located near the Columbia River, which is extensively developed for hydroelectric generation, it is used as a natural laboratory for studying a large-scale operating system. Although the impacts studied result from a particular system of dams and operating procedures and occur within a specific ecosystem, the results of these studies have application at hydroelectric generating facilities throughout the United States.

  3. A Research Module for the Organic Chemistry Laboratory: Multistep Synthesis of a Fluorous Dye Molecule.

    Science.gov (United States)

    Slade, Michael C; Raker, Jeffrey R; Kobilka, Brandon; Pohl, Nicola L B

    2014-01-14

    A multi-session research-like module has been developed for use in the undergraduate organic teaching laboratory curriculum. Students are tasked with planning and executing the synthesis of a novel fluorous dye molecule and using it to explore a fluorous affinity chromatography separation technique, which is the first implementation of this technique in a teaching laboratory. Key elements of the project include gradually introducing students to the use of the chemical literature to facilitate their searching, as well as deliberate constraints designed to force them to think critically about reaction design and optimization in organic chemistry. The project also introduces students to some advanced laboratory practices such as Schlenk techniques, degassing of reaction mixtures, affinity chromatography, and microwave-assisted chemistry. This provides students a teaching laboratory experience that closely mirrors authentic synthetic organic chemistry practice in laboratories throughout the world.

  4. Radar research at The Pennsylvania State University Radar and Communications Laboratory

    Science.gov (United States)

    Narayanan, Ram M.

    2017-05-01

    The Radar and Communications Laboratory (RCL) at The Pennsylvania State University is at the forefront of radar technology and is engaged in cutting edge research in all aspects of radar, including modeling and simulation studies of novel radar paradigms, design and development of new types of radar architectures, and extensive field measurements in realistic scenarios. This paper summarizes the research at The Pennsylvania State University's Radar and Communications Laboratory and relevant collaborative research with several groups over the past 15 years in the field of radar and related technologies, including communications, radio frequency identification (RFID), and spectrum sensing.

  5. The Central Importance of Laboratories for Reducing Waste in Biomedical Research.

    Science.gov (United States)

    Stroth, Nikolas

    2016-12-01

    The global biomedical research enterprise is driving substantial advances in medicine and healthcare. Yet it appears that the enterprise is rather wasteful, falling short of its true innovative potential. Suggested reasons are manifold and involve various stakeholders, such that there is no single remedy. In the present paper, I will argue that laboratories are the basic working units of the biomedical research enterprise and an important site of action for corrective intervention. Keeping laboratories relatively small will enable better training and mentoring of individual scientists, which in turn will yield better performance of the scientific workforce. The key premise of this argument is that people are at the heart of the successes and failures of biomedical research, yet the human dimension of science has been unduly neglected in practice. Renewed focus on the importance of laboratories and their constituent scientists is one promising approach to reducing waste and increasing efficiency within the biomedical research enterprise.

  6. U.S. Army Aeromedical Research Laboratory Annual Progress Report Fiscal Year 2009

    Science.gov (United States)

    2010-02-10

    of this research was to determine the operational efficacy of refractive surgery for specialized Army applications. Additionally, higher order...topic of Cervical Disc Surgery Options for Military Personnel. LTC Shean Phelps was invited to present on biomechanics- and physiology-based...Laboratory — Fiscal Year 2009 17 Research Activities Shock and Vibration Isolation System for Patient Litters Personnel in the ACE Branch are

  7. "Deja Vu"? A Decade of Research on Language Laboratories, Television and Video in Language Learning

    Science.gov (United States)

    Vanderplank, Robert

    2010-01-01

    The developments in the last ten years in the form of DVD, streaming video, video on demand, interactive television and digital language laboratories call for an assessment of the research into language teaching and learning making use of these technologies and the learning paradigms underpinning them. This paper surveys research on language…

  8. A Graduate Laboratory Course on Biodiesel Production Emphasizing Professional, Teamwork, and Research Skills

    Science.gov (United States)

    Leavesley, West

    2011-01-01

    In this article we report on the use of a graduate "Special Topics" course to provide vital research and practical laboratory experience, within the context of developing a chemical process to manufacture biodiesel from algal sources. This course contained several key components that we believe are necessary skills in graduate research: 1) a…

  9. Promoting Science Outdoor Activities for Elementary School Children: Contributions from a Research Laboratory

    Science.gov (United States)

    Boaventura, Diana; Faria, Claudia; Chagas, Isabel; Galvao, Cecilia

    2013-01-01

    The purposes of the study were to analyse the promotion of scientific literacy through practical research activities and to identify children's conceptions about scientists and how they do science. Elementary school children were engaged in two scientific experiments in a marine biology research laboratory. A total of 136 students answered a…

  10. Fred Hutchinson Cancer Research Center, Seattle, Washington: Laboratories for the 21st Century Case Studies (Revision)

    Energy Technology Data Exchange (ETDEWEB)

    2002-03-01

    This case study was prepared by participants in the Laboratories for the 21st Century program, a joint endeavor of the U.S. Environmental Protection Agency and the U.S. Department of Energy's Federal Energy Management Program. The goal of this program is to foster greater energy efficiency in new laboratory buildings for both the public and the private sectors. Retrofits of existing laboratories are also encouraged. The energy-efficient features of the laboratories in the Fred Hutchinson Cancer Research Center complex in Seattle, Washington, include extensive use of efficient lighting, variable-air-volume controls, variable-speed drives, motion sensors, and high-efficiency chillers and motors. With about 532,000 gross square feet, the complex is estimated to use 33% less electrical energy than most traditional research facilities consume because of its energy-efficient design and features.

  11. Method to Increase Undergraduate Laboratory Student Confidence in Performing Independent Research

    Directory of Open Access Journals (Sweden)

    Colton E. Kempton

    2017-05-01

    Full Text Available The goal of an undergraduate laboratory course should be not only to introduce the students to biology methodologies and techniques, but also to teach them independent analytical thinking skills and proper experiment design.  This is especially true for advanced biology laboratory courses that undergraduate students typically take as a junior or senior in college.  Many courses achieve the goal of teaching techniques, but fail to approach the larger goal of teaching critical thinking, experimental design, and student independence.  Here we describe a study examining the application of the scaffolding instructional philosophy in which students are taught molecular techniques with decreasing guidance to force the development of analytical thinking skills and prepare undergraduate students for independent laboratory research. This method was applied to our advanced molecular biology laboratory class and resulted in an increase of confidence among the undergraduate students in their abilities to perform independent research.

  12. Fred Hutchinson Cancer Research Center, Seattle, Washington: Laboratories for the 21st Century Case Studies

    Energy Technology Data Exchange (ETDEWEB)

    2001-12-01

    This case study was prepared by participants in the Laboratories for the 21st Century program, a joint endeavor of the U.S. Environmental Protection Agency and the U.S. Department of Energy's Federal Energy Management Program. The goal of this program is to foster greater energy efficiency in new laboratory buildings for both the public and the private sectors. Retrofits of existing laboratories are also encouraged. The energy-efficient features of the laboratories in the Fred Hutchinson Cancer Research Center complex in Seattle, Washington, include extensive use of efficient lighting, variable-air-volume controls, variable-speed drives, motion sensors, and high-efficiency chillers and motors. With about 532,000 gross square feet, the complex is estimated to use 33% less electrical energy than most traditional research facilities consume because of its energy-efficient design and features.

  13. Some recent advances of shock wave physics research at the Laboratory for Shock Wave and Detonation Physics Research

    CERN Document Server

    Jing Fu Qian

    2002-01-01

    Progress made in recent years on three topics that have been investigated at the Laboratory for Shock Wave and Detonation Physics Research are presented in this report. (1) A new equation of state (EOS) has been derived which can be used from a standard state to predict state variable change along an isobaric path. Good agreements between calculations for some representative metals using this new EOS and experiments have been found, covering a wide range from hundreds of MPa to hundreds of GPa and from ambient temperature to tens of thousands of GPa. (2) An empirical relation of Y/G = constant (Y is yield strength, G is shear modulus) at HT-HP has been reinvestigated and confirmed by shock wave experiment. 93W alloy was chosen as a model material. The advantage of this relation is that it is beneficial to formulate a kind of simplified constitutive equation for metallic solids under shock loading, and thus to faithfully describe the behaviours of shocked solids through hydrodynamic simulations. (3) An attempt...

  14. Planning an Automatic Fire Detection, Alarm, and Extinguishing System for Research Laboratories

    Directory of Open Access Journals (Sweden)

    Rostam Golmohamadi

    2014-04-01

    Full Text Available Background & Objectives: Educational and research laboratories in universities have a high risk of fire, because they have a variety of materials and equipment. The aim of this study was to provide a technical plan for safety improvement in educational and research laboratories of a university based on the design of automatic detection, alarm, and extinguishing systems . Methods : In this study, fire risk assessment was performed based on the standard of Military Risk Assessment method (MIL-STD-882. For all laboratories, detection and fire alarm systems and optimal fixed fire extinguishing systems were designed. Results : Maximum and minimum risks of fire were in chemical water and wastewater (81.2% and physical agents (62.5% laboratories, respectively. For studied laboratories, we designed fire detection systems based on heat and smoke detectors. Also in these places, fire-extinguishing systems based on CO2 were designed . Conclusion : Due to high risk of fire in studied laboratories, the best control method for fire prevention and protection based on special features of these laboratories is using automatic detection, warning and fire extinguishing systems using CO2 .

  15. Flexible System Integration and Advanced Hierarchical Control Architectures in the Microgrid Research Laboratory of Aalborg University

    DEFF Research Database (Denmark)

    Meng, Lexuan; Hernández, Adriana Carolina Luna; Diaz, Enrique Rodriguez

    2016-01-01

    This paper presents the system integration and hierarchical control implementation in an inverter-based microgrid research laboratory (MGRL) in Aalborg University, Denmark. MGRL aims to provide a flexible experimental platform for comprehensive studies of microgrids. The structure of the laboratory...... system supervision, advanced secondary and tertiary management are realized in a microgrid central controller. The software and hardware schemes are described. Several example case studies are introduced and performed in order to achieve power quality regulation, energy management and flywheel energy...

  16. Reliability and validity of job content questionnaire for university research laboratory staff in Malaysia.

    Science.gov (United States)

    Nehzat, F; Huda, B Z; Tajuddin, S H Syed

    2014-03-01

    Job Content Questionnaire (JCQ) has been proven a reliable and valid instrument to assess job stress in many countries and among various occupations. In Malaysia, both English and Malay versions of the JCQ have been administered to automotive workers, schoolteachers, and office workers. This study assessed the reliability and validity of the instrument with research laboratory staff in a university. A cross sectional study was conducted among 258 research laboratory staff in Universiti Putra Malaysia (UPM). Malaysian laboratory staff who have worked for at least one year were randomly selected from nine faculties and institutes in the university that have research laboratory. A self-administered English and Malay version of Job Content Questionnaire (JCQ) was used. Three major scales of JCQ: decision latitude, psychological job demands, and social support were assessed. Cronbach's alpha coefficients of two scales were acceptable, decision latitude and psychological job demands (0.70 and 0.72, respectively), while Cronbach's alpha coefficient for social support (0.86) was good. Exploratory factor analysis showed five factors that correspond closely to the theoretical construct of the questionnaire. The results of this research suggest that the JCQ is reliable and valid for examining psychosocial work situations and job strain among research laboratory staff. Further studies should be done for confirmative results, and further evaluation is needed on the decision authority subscale for this occupation.

  17. Research on risk long range identification for vessel traffic dynamic system

    Science.gov (United States)

    Qi, Ji; Guo, Ruijuan; Wang, Xiaoyu; Zhang, Hainan

    2017-09-01

    Vessel Long-range identification and tracking system has already been widely installed and applied in vessel. In this paper AIS system, vessel reporting system and LRIT in China are compared and analyzed based on the coverage area, confidentiality and accuracy of the LRIT information. Vessel Long-range identification and tracking model is established through a combination of AIS with LRIT system, which is applied to the research of vessel traffic dynamic system risk long range identification. Finally, the application of LRIT in the maritime field is discussed.

  18. Definition of experiments and instruments for a communication/navigation research laboratory. Volume 4: Programmatics

    Science.gov (United States)

    1972-01-01

    Details are provided for scheduling, cost estimates, and support research and technology requirements for a space shuttle supported manned research laboratory to conduct selected communication and navigation experiments. A summary of the candidate program and its time phasing is included, as well as photographs of the 1/20 scale model of the shuttle supported Early Comm/Nav Research Lab showing the baseline, in-bay arrangement and the out-of-bay configuration.

  19. USAF Summer Research Program - 1993 Graduate Student Research Program Final Reports, Volume 8, Phillips Laboratory

    Science.gov (United States)

    1994-12-01

    MS Laboratory: AL/CF Nutrition and Food Scienc Auburn University Vol-Page No: 7-11 Auburn, AL 36849-5605 Tornow, Carina Field: Psychology BS...described in [Kong 1986] Snell’s law can be written as: Nisin (01) = N2sin(02 ) (2.1) where N. is the refractive index in region x, and 0, is the incident

  20. Capabilities for high explosive pulsed power research at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Goforth, James H [Los Alamos National Laboratory; Oona, Henn [Los Alamos National Laboratory; Tasker, Douglas G [Los Alamos National Laboratory; Kaul, A M [Los Alamos National Laboratory

    2008-01-01

    Research on topics requiring high magnetic fields and high currents have been pursued using high explosive pulsed power (HEPP) techniques since the 1950s at Los Alamos National Laboratory. We have developed many sophisticated HEPr systems through the years, and most of them depend on technology available from the nuclear weapons program. Through the 1980s and 1990s, our budgets would sustain parallel efforts in zpinch research using both HEPr and capacitor banks. In recent years, many changes have occurred that are driven by concerns such as safety, security, and environment, as well as reduced budgets and downsizing of the National Nuclear Security Administration (NNSA) complex due to the end of the cold war era. In this paper, we review the teclmiques developed to date, and adaptations that are driven by changes in budgets and our changing complex. One new Ranchero-based solid liner z-pinch experimental design is also presented. Explosives that are cast to shape instead of being machined, and initiation systems that depend on arrays of slapper detonators are important new tools. Some materials that are seen as hazardous to the environment are avoided in designs. The process continues to allow a wide range of research however, and there are few, if any, experiments that we have done in the past that could not be perform today. The HErr firing facility at Los Alamos continues to have a 2000 lb. high explosive limit, and our 2.4 MJ capacitor bank remains a mainstay of the effort. Modem diagnostic and data analysis capabilities allow fewer personnel to achieve better results, and in the broad sense we continue to have a robust capability.

  1. Establishment of a Laboratory for Biofuels Research at the University of Kentucky

    Energy Technology Data Exchange (ETDEWEB)

    Crocker, Mark [Univ. of Kentucky, Lexington, KY (United States). Center for Applied Energy Research; Crofcheck, Czarena [Univ. of Kentucky, Lexington, KY (United States). Center for Applied Energy Research; Andrews, Rodney [Univ. of Kentucky, Lexington, KY (United States). Center for Applied Energy Research

    2013-03-29

    This project was aimed at the development of the biofuels industry in Kentucky by establishing a laboratory to develop improved processes for biomass utilization. The facility is based at the University of Kentucky Center for Applied Energy Research and the Department of Biosystems and Agricultural Engineering, and constitutes an “open” laboratory, i.e., its equipment is available to other Kentucky researchers working in the area. The development of this biofuels facility represents a significant expansion of research infrastructure, and will provide a lasting resource for biobased research endeavors at the University of Kentucky. In order to enhance the laboratory's capabilities and contribute to on-going biofuels research at the University of Kentucky, initial research at the laboratory has focused on the following technical areas: (i) the identification of algae strains suitable for oil production, utilizing flue gas from coal-fired power plants as a source of CO2; (ii) the conversion of algae to biofuels; and (iii) the development of methods for the analysis of lignin and its deconstruction products. Highlights from these activities include the development of catalysts for the upgrading of lipids to hydrocarbons by means of decarboxylation/decarbonylation (deCOx), a study of bio-oil production from the fast pyrolysis of algae (Scenedesmus), and the application of pyrolytic gas chromatography coupled with mass spectrometry (Py-GC-MS) to the characterization of high lignin biomass feedstocks.

  2. Annual Report FY2011: Establishment of a Laboratory for Biofuels Research at the University of Kentucky

    Energy Technology Data Exchange (ETDEWEB)

    Crocker, Mark [Univ. of Kentucky, Lexington, KY (United States). Center for Applied Energy Research; Crofcheck, Czarena [Univ. of Kentucky, Lexington, KY (United States). Center for Applied Energy Research; Andrews, Rodney [Univ. of Kentucky, Lexington, KY (United States). Center for Applied Energy Research

    2011-12-21

    This project is aimed at the development of the biofuels industry in Kentucky by establishing a laboratory to develop improved processes for biomass utilization. The facility is based at the University of Kentucky Center for Applied Energy Research and the Department of Biosystems and Agricultural Engineering, and constitutes an open laboratory, i.e., its equipment is available to other Kentucky researchers working in the area. The development of this biofuels facility represents a significant expansion of research infrastructure, and will provide a lasting resource for biobased research endeavors at the University of Kentucky. In order to enhance the laboratory's capabilities and contribute to on-going biofuels research at the University of Kentucky, initial research at the laboratory has focused on the following technical areas: (i) the identification of algae strains suitable for oil production, utilizing flue gas from coal-fired power plants as a source of CO2; (ii) the conversion of algae to biofuels; and (iii) thermochemical methods for the deconstruction of lignin. Highlights from these activities include a detailed study of bio-oil production from the fast pyrolysis of microalgae (Scenedesmus sp.) and the application of pyrolytic gas chromatography coupled with mass spectrometry (Py-GC-MS) to the characterization of high lignin biomass feedstocks.

  3. The LabBase system for data management in large scale biology research laboratories.

    Science.gov (United States)

    Goodman, N; Rozen, S; Stein, L D; Smith, A G

    1998-01-01

    The development of laboratory information management systems (LIMSs) for large scale biology research projects can be a challenging problem. Many such projects generate complex datasets via complex procedures that undergo continuous refinement. A key software challenge is to simplify the database-development task so that databases can be built and modified quickly enough to keep pace with changing project-requirements. LabBase extends the facilities offered by relational database systems to simplify the task of creating databases for large scale biology research projects. LabBase provides a structural object data model, similar to ACEDB, and adds to this the concepts of Materials, Steps, and States: Materials are objects representing the identifiable things that participate in a laboratory protocol; Steps are objects reporting the results of a laboratory or analytical procedure; and States are objects denoting places in a laboratory protocol. The system provides a data definition language for succinctly defining laboratory databases, and operations for conveniently storing and retrieving data in such databases. The system also provides support for workflow management. LabBase is implemented in Perl5 and provides a natural interface for laboratory application programs written in Perl. The software is freely available. Contact the authors. nat@jax.org

  4. Research publications of the H.J. Andrews Experimental Forest, Cascade Range, Oregon: 1988 supplement.

    Science.gov (United States)

    T. Blinn; F.J. Swanson; A. McKee

    1988-01-01

    This bibliography updates the list of publications, abstracts, theses, and unpublished reports included in "Research Publications of the H.J. Andrews Experimental Forest, Cascade Range, Oregon, 1948 to 1986," General Technical Report PNW-GTR-201. Citations are referenced under appropriate keywords.

  5. Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: Diagnostic cohort study.

    Directory of Open Access Journals (Sweden)

    Kate Birnie

    Full Text Available To compare the validity of diagnosis of urinary tract infection (UTI through urine culture between samples processed in routine health service laboratories and those processed in a research laboratory.We conducted a prospective diagnostic cohort study in 4808 acutely ill children aged <5 years attending UK primary health care. UTI, defined as pure/predominant growth ≥105 CFU/mL of a uropathogen (the reference standard, was diagnosed at routine health service laboratories and a central research laboratory by culture of urine samples. We calculated areas under the receiver-operator curve (AUC for UTI predicted by pre-specified symptoms, signs and dipstick test results (the "index test", separately according to whether samples were obtained by clean catch or nappy (diaper pads.251 (5.2% and 88 (1.8% children were classified as UTI positive by health service and research laboratories respectively. Agreement between laboratories was moderate (kappa = 0.36; 95% confidence interval [CI] 0.29, 0.43, and better for clean catch (0.54; 0.45, 0.63 than nappy pad samples (0.20; 0.12, 0.28. In clean catch samples, the AUC was lower for health service laboratories (AUC = 0.75; 95% CI 0.69, 0.80 than the research laboratory (0.86; 0.79, 0.92. Values of AUC were lower in nappy pad samples (0.65 [0.61, 0.70] and 0.79 [0.70, 0.88] for health service and research laboratory positivity, respectively than clean catch samples.The agreement of microbiological diagnosis of UTI comparing routine health service laboratories with a research laboratory was moderate for clean catch samples and poor for nappy pad samples and reliability is lower for nappy pad than for clean catch samples. Positive results from the research laboratory appear more likely to reflect real UTIs than those from routine health service laboratories, many of which (particularly from nappy pad samples could be due to contamination. Health service laboratories should consider adopting procedures used

  6. THE PELLETS APPLICATION IN LABORATORY RESEARCHING OF INHIBITIVE MUD/SHALE INTERACTION

    Directory of Open Access Journals (Sweden)

    Borivoje Pašić

    2012-12-01

    Full Text Available Wellbore instability appears to be a serious problem during drilling process through shale. Shales instability cause basically comes out of its mineralogical composition (especially clay minerals content and physico-chemical properties. Many research activities about shale instability causes and shale properties (affecting shale behavior during interaction with water phase of different drilling muds definition have been carried out by now. In these laboratory tests were used original shales samples given by coring process or collecting shale cuttings from shale shakers, and different shale samples from outcrop. From this reason is very difficult compare laboratory tests results given by different authors. Possible solution is use artificial shale samples (pellets with exact mineralogical composition, enabling extensive laboratory tests and tests results comparison. In this paper presented laboratory tests of pellets swelling in inhibitive muds (the paper is published in Croatian.

  7. USAF Summer Research Program - 1993 Summer Research Extension Program Final Reports, Volume 1A, Armstrong Laboratory

    Science.gov (United States)

    1994-11-01

    Mammalian Cells and Dr. Donald Robinson Cell Cultures Chemistry Xavier University of Louisiana, New Orleans , LA AL/OE 16 Analysis of Isocyanate...Science 17 Speed-Up of the Phase Diversity Method Via Reduced Region & Dr. Johanna Stenzel Optimization Dimen. Arts & Sciences University of Houston...New Orleans , New Orleans , LA WLUFI viii 1993 SREP FINAL REPORTS Wright Laboratory VOLUME 4B Report Title Report # Author’s University Report Author 19

  8. NNSA Laboratory Directed Research and Development Program 2008 Symposium--Focus on Energy Security

    Energy Technology Data Exchange (ETDEWEB)

    Kotta, P R; Sketchley, J A

    2008-08-20

    The Laboratory Directed Research and Development (LDRD) Program was authorized by Congress in 1991 to fund leading-edge research and development central to the national laboratories core missions. LDRD anticipates and engages in projects on the forefront of science and engineering at the Department of Energy (DOE) national laboratories, and has a long history of addressing pressing national security needs at the National Nuclear Security Administration (NNSA) laboratories. LDRD has been a scientific success story, where projects continue to win national recognition for excellence through prestigious awards, papers published and cited in peer-reviewed journals, mainstream media coverage, and patents granted. The LDRD Program is also a powerful means to attract and retain top researchers from around the world, to foster collaborations with other prominent scientific and technological institutions, and to leverage some of the world's most technologically advanced assets. This enables the LDRD Program to invest in high-risk and potentially high-payoff research that creates innovative technical solutions for some of our nation's most difficult challenges. Worldwide energy demand is growing at an alarming rate, as developing nations continue to expand their industrial and economic base on the back of limited global resources. The resulting international conflicts and environmental consequences pose serious challenges not only to this nation, but to the international community as well. The NNSA and its national security laboratories have been increasingly called upon to devote their scientific and technological capabilities to help address issues that are not limited solely to the historic nuclear weapons core mission, but are more expansive and encompass a spectrum of national security missions, including energy security. This year's symposium highlights some of the exciting areas of research in alternative fuels and technology, nuclear power, carbon

  9. Pacific Northwest Laboratory annual report for 1990 to the DOE Office of Energy Research

    Energy Technology Data Exchange (ETDEWEB)

    Park, J.F.

    1991-06-01

    This report summarizes progress on OHER human health, biological, and general life sciences research programs conducted at PNL in FY 1990. The research develops the knowledge and scientific principles necessary to identify understand, and anticipate the long-term health consequences of energy-related radiation and chemicals. Our continuing emphasis is to decrease the uncertainty of health risk estimates from existing and developing energy-related technologies through an increased of understanding of how radiation and chemicals cause biological damage. The sequence of this report of PNL research reflects the OHER programmatic structure. The first section, on human health research, concerns epidemiological and statistical studies for assessing health risks. The next section contains reports of biological research in laboratory animals and in vitro cell systems, including research with radionuclides and chemicals. The general life sciences research section reports research conducted for the OHER human genome research program.

  10. Geoengineering Research for a Deep Underground Science and Engineering Laboratory in Sedimentary Rock

    Science.gov (United States)

    Mauldon, M.

    2004-12-01

    A process to identify world-class research for a Deep Underground Science and Engineering Laboratory (DUSEL) in the USA has been initiated by NSF. While allowing physicists to study, inter alia, dark matter and dark energy, this laboratory will create unprecedented opportunities for biologists to study deep life, geoscientists to study crustal processes and geoengineers to study the behavior of rock, fluids and underground cavities at depth, on time scales of decades. A substantial portion of the nation's future infrastructure is likely to be sited underground because of energy costs, urban crowding and vulnerability of critical surface facilities. Economic and safe development of subsurface space will require an improved ability to engineer the geologic environment. Because of the prevalence of sedimentary rock in the upper continental crust, much of this subterranean infrastructure will be hosted in sedimentary rock. Sedimentary rocks are fundamentally anisotropic due to lithology and bedding, and to discontinuities ranging from microcracks to faults. Fractures, faults and bedding planes create structural defects and hydraulic pathways over a wide range of scales. Through experimentation, observation and monitoring in a sedimentary rock DUSEL, in conjunction with high performance computational models and visualization tools, we will explore the mechanical and hydraulic characteristics of layered rock. DUSEL will permit long-term experiments on 100 m blocks of rock in situ, accessed via peripheral tunnels. Rock volumes will be loaded to failure and monitored for post-peak behavior. The response of large rock bodies to stress relief-driven, time-dependent strain will be monitored over decades. Large block experiments will be aimed at measurement of fluid flow and particle/colloid transport, in situ mining (incl. mining with microbes), remediation technologies, fracture enhancement for resource extraction and large scale long-term rock mass response to induced

  11. Researching Complex Heat, Air and Moisture Interactions for a Wide-Range of Building Envelope Systems and Environmental Loads

    Energy Technology Data Exchange (ETDEWEB)

    Karagiozis, A.N.

    2007-05-15

    This document serves as the final report documenting work completed by Oak Ridge National Laboratory (ORNL) and the Fraunhofer Institute in Building Physics (Holzkirchen, Germany) under an international CRADA No. 0575 with Fraunhofer Institute of Bauphysics of the Federal Republic of Germany for Researching Complex Heat, Air and Moisture Interactions for a Wide Range of Building Envelope Systems and Environmental Loads. This CRADA required a multi-faceted approach to building envelope research that included a moisture engineering approach by blending extensive material property analysis, laboratory system and sub-system thermal and moisture testing, and advanced moisture analysis prediction performance. The Participant's Institute for Building physics (IBP) and the Contractor's Buildings Technology Center (BTC) identified potential research projects and activities capable of accelerating and advancing the development of innovative, low energy and durable building envelope systems in diverse climates. This allowed a major leverage of the limited resources available to ORNL to execute the required Department of Energy (DOE) directives in the area of moisture engineering. A joint working group (ORNL and Fraunhofer IBP) was assembled and a research plan was executed from May 2000 to May 2005. A number of key deliverables were produced such as adoption of North American loading into the WUFI-software. in addition the ORNL Weather File Analyzer was created and this has been used to address environmental loading for a variety of US climates. At least 4 papers have been co-written with the CRADA partners, and a chapter in the ASTM Manual 40 on Moisture Analysis and Condensation Control. All deliverables and goals were met and exceeded making this collaboration a success to all parties involves.

  12. Demonstrating S-NPP VIIRS Products with the Naval Research Laboratory R&D Websites

    Science.gov (United States)

    Kuciauskas, A. P.; Hawkins, J.; Solbrig, J.; Bankert, R.; Richardson, K.; Surratt, M.; Miller, S. D.; Kent, J.

    2014-12-01

    The Naval Research Laboratory, Marine Meteorology Division in Monterey, CA (NRL-MRY) has been developing and providing the global community with VIIRS-derived state of the art image products on three operational websites: · NexSat: www.nrlmry.navy.mil/NEXSAT.html · VIIRS Page: www.nrlmry.navy.mil/VIIRS.html · Tropical Cyclone Page: www.nrlmry.navy.mil/TC.html These user-friendly websites are accessed by the global public with a daily average of 250,000 and 310,000 web hits for NexSat and Tropical Cyclone websites, respectively. Users consist of operational, research, scientific field campaigns, academia, and weather enthusiasts. The websites also contain ancillary products from 5 geostationary and 27 low earth orbiting sensors, ranging from visible through microwave channels. NRL-MRY also leverages the NRL global and regional numerical weather prediction (NWP) models for assessing cloud top measurements and synoptic overlays. With collaborations at CIMSS' Direct Readout site along with the AFWA IDPS-FNMOC and NOAA IDPS portals, a robust component to our websites are product latencies that typically satisfy operational time constraints necessary for planning purposes. Given these resources, NRL-MRY acquires ~2TBytes of data and produces 100,000 image products on a daily basis. In partnership with the COMET program, our product tutorials contain simple and graphically enhanced descriptions that accommodate users ranging from basic to advanced understanding of satellite meteorology. This presentation will provide an overview of our website functionality: animations, co-registered formats, and Google Earth viewing. Through imagery, we will also demonstrate the superiority of VIIRS against its heritage sensor counterparts. A focal aspect will be the demonstration of the VIIRS Day Night Band (DNB) in detecting nighttime features such as wildfires, volcanic ash, Arctic sea ice, and tropical cyclones. We also plan to illustrate how NexSat and VIIRS websites demonstrate

  13. Wireless Monitoring Study in the Meuse / Haute-Marne Underground Research Laboratory, France - 12046

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Kei; Eto, Jiro; Tanabe, Hiromi [Radioactive Waste Management Funding and Research Center - RWMC (Japan); Mayer, Stefan; Bertrand, Johan [National Radioactive Waste Management Agency - ANDRA (France); Takamura, Hisashi; Suyama, Yasuhiro [Kajima Corporation (Japan)

    2012-07-01

    Two types of wireless transmission systems using ultra low frequency (8.5 kHz) were developed and used in the Callovo-Oxfordian argillites layer in the Meuse / Haute-Marne Underground Research Laboratory (CMHM URL) in France. Short-range and mid-range transmission antennas received data transmitted from 25 m to 50 m away. From the results of two series of tests, it is clear that transmission is practical when the received voltage is larger than the received noise. However, it is also clear that wireless transmission in the CMHM URL gallery is affected by the electromagnetic noise level and steel components, and the maximum transmission distance depends on the S/N ratio. The mid-range transmission antenna achieved a transmission distance of 240 m in the surface test, where the electromagnetic noise level was small and there was no environmental attenuation. The short-range transmission antenna achieved a transmission distance of 25 m in the surface test and in the CMHM URL gallery. As the clay layer of the CMHM URL had little effect on the attenuation of the electromagnetic field, transmission over 200 m might be possible in the CMHM URL when the electromagnetic noise level is small enough and there are no significant factors enhancing attenuation. But in reality, the possible transmission distance was around 50 m. In order to show the transmitter's ability, it is preferable to keep some distance between steel components and the transmitter. The most effective way to use this transmitter is to put it in a borehole drilled from a gallery to outside of a gallery around 10 m length. In this way, it might be possible to avoid almost of all the influence of steel components. For the position of receiver, the recommendation is the same as for the transmitter. That is, place the receiver where the incoming signal from the transmitter suffers little attenuation from steel components. Therefore, the option of implementing a receiving antenna in a borehole is required

  14. Transposing from the laboratory to the classroom to generate authentic research experiences for undergraduates.

    Science.gov (United States)

    Burnette, James M; Wessler, Susan R

    2013-02-01

    Large lecture classes and standardized laboratory exercises are characteristic of introductory biology courses. Previous research has found that these courses do not adequately convey the process of scientific research and the excitement of discovery. Here we propose a model that provides beginning biology students with an inquiry-based, active learning laboratory experience. The Dynamic Genome course replicates a modern research laboratory focused on eukaryotic transposable elements where beginning undergraduates learn key genetics concepts, experimental design, and molecular biological skills. Here we report on two key features of the course, a didactic module and the capstone original research project. The module is a modified version of a published experiment where students experience how virtual transposable elements from rice (Oryza sativa) are assayed for function in transgenic Arabidopsis thaliana. As part of the module, students analyze the phenotypes and genotypes of transgenic plants to determine the requirements for transposition. After mastering the skills and concepts, students participate in an authentic research project where they use computational analysis and PCR to detect transposable element insertion site polymorphism in a panel of diverse maize strains. As a consequence of their engagement in this course, students report large gains in their ability to understand the nature of research and demonstrate that they can apply that knowledge to independent research projects.

  15. Senior Research Connects Students with a Living Laboratory As Part of an Integrated Crop and Livestock System

    Science.gov (United States)

    Senturklu, Songul; Landblom, Douglas; Brevik, Eric C.

    2015-04-01

    highest expenses in beef cattle production. Senior research investigating the impact of livestock integration and multi-species cover crop grown within the crop rotation is studying changes in soil attributes resulting from the crop-animal integration by measuring bulk density and in-season soil fertility in the crop rotation. These responses are further contrasted with results from within the crop rotation and responses from perennial native range. Students that become engaged in the research represent a broad cross section of the consuming public and include high school junior and senior students, college undergraduate students that conduct research projects, postdoctoral research scientists engaged in senior level research, agricultural extension educators, and finally, farmer and rancher businessmen. The integrated nature of the research provides a wealth of learning opportunities for these various groups. For the high school students, visits to the living laboratory increase awareness and introduces students to a potential career path in agriculture, natural resource fields, and the many allied vocational fields that support agriculture. When college undergraduate students visit the living laboratory, they seek to address a researchable question or a problem in agriculture, while fulfilling requirements for graduation by conducting a research project. Because postdoctoral students want to be actively engaged in research and advanced learning, they are interested in conducting research in the living laboratory that can be published in peer reviewed journals. Agricultural extension educators, who advise farmers and ranchers, are looking for research results from the living laboratory that can be convey to their constituents. Farmers and ranchers participate in workshop events that give them face-to-face learning opportunities that they can use to effect change in their farm and ranch businesses. Each of these demographic groups are unique in their interest in the

  16. Research in free-flying robots and flexible manipulators at the Stanford Aerospace Robotics Laboratory

    Science.gov (United States)

    Ballhaus, W. L.; Alder, L. J.; Chen, V. W.; Dickson, W. C.; Ullman, M. A.; Wilson, E.

    1993-01-01

    Over the last ten years, the Stanford Aerospace Robotics Laboratory (ARL) has developed a hardware facility in which a number of space robotics issues have been, and continue to be addressed. This paper reviews two of the current ARL research areas: navigation and control of free flying space robots, and modeling and control of extremely flexible space structures.

  17. Second-language acquisition research in the laboratory: possibilities and limitations

    NARCIS (Netherlands)

    Hulstijn, J.H.

    1997-01-01

    This paper discusses some possibilities and limitations of laboratory research methods for testing theories of second language acquisition. The paper includes a review of 20 experimental lab studies. The review focuses on the motivation for conducting lab studies, the use of artificial or

  18. Preparing a Laboratory-Based Thesis: Chinese International Research Students' Experiences of Supervision

    Science.gov (United States)

    McClure, Joanne W.

    2005-01-01

    This qualitative study examined Chinese international laboratory-based research students' experiences of supervision during the first six to eighteen months of their candidature in Singapore. The experiences of marginalization in student/supervisory relationship identified in the study, particularly in the first six months, may very largely be…

  19. Infusing Bioinformatics and Research-Like Experience into a Molecular Biology Laboratory Course

    Science.gov (United States)

    Nogaj, Luiza A.

    2014-01-01

    A nine-week laboratory project designed for a sophomore level molecular biology course is described. Small groups of students (3-4 per group) choose a tumor suppressor gene (TSG) or an oncogene for this project. Each group researches the role of their TSG/oncogene from primary literature articles and uses bioinformatics engines to find the gene…

  20. The National Sedimentation Laboratory: 50 years of soil and water research in a changing environment

    Science.gov (United States)

    The papers in this issue are based on selected presentations made at a symposium convened to celebrate the 50th anniversary of the founding of the National Sedimentation Laboratory (NSL) of the US Department of Agriculture (USDA), Agricultural Research Service (ARS), located in Oxford, Mississippi. ...

  1. Using Green Chemistry Principles as a Framework to Incorporate Research into the Organic Laboratory Curriculum

    Science.gov (United States)

    Lee, Nancy E.; Gurney, Rich; Soltzberg, Leonard

    2014-01-01

    Despite the accepted pedagogical value of integrating research into the laboratory curriculum, this approach has not been widely adopted. The activation barrier to this change is high, especially in organic chemistry, where a large number of students are required to take this course, special glassware or setups may be needed, and dangerous…

  2. Savannah River Ecology Laboratory. Annual technical progress report of ecological research

    Energy Technology Data Exchange (ETDEWEB)

    Smith, M.H.

    1996-07-31

    The Savannah River Ecology Laboratory (SREL) is a research unit of the University of Georgia (UGA). The overall mission of the Laboratory is to acquire and communicate knowledge of ecological processes and principles. SREL conducts basic and applied ecological research, as well as education and outreach programs, under a contract with the U.S. Department of Energy (DOE) at the Savannah River Site (SRS) near Aiken, South Carolina. Significant accomplishments were made during the past year in the areas of research, education and service. The Laboratory`s research mission was fulfilled with the publication of two books and 143 journal articles and book chapters by faculty, technical and students, and visiting scientists. An additional three books and about 80 journal articles currently are in press. Faculty, technician and students presented 193 lectures, scientific presentations, and posters to colleges and universities, including minority institutions. Dr. J Vaun McArthur organized and conducted the Third Annual SREL Symposium on the Environment: New Concepts in Strewn Ecology: An Integrative Approach. Dr. Michael Newman conducted a 5-day course titled Quantitative Methods in Ecotoxicology, and Dr. Brian Teppen of The Advanced Analytical Center for Environmental Sciences (AACES) taught a 3-day short course titled Introduction to Molecular Modeling of Environmental Systems. Dr. I. Lehr Brisbin co-hosted a meeting of the Crocodile Special Interest Group. Dr. Rebecca Sharitz attended four symposia in Japan during May and June 1996 and conducted meetings of the Executive Committee and Board of the International Association for Ecology (ENTECOL).

  3. Discovering Inexpensive, Effective Catalysts for Solar Energy Conversion: An Authentic Research Laboratory Experience

    Science.gov (United States)

    Shaner, Sarah E.; Hooker, Paul D.; Nickel, Anne-Marie; Leichtfuss, Amanda R.; Adams, Carissa S.; de la Cerda, Dionisia; She, Yuqi; Gerken, James B.; Pokhrel, Ravi; Ambrose, Nicholas J.; Khaliqi, David; Stahl, Shannon S.; Schuttlefield Christus, Jennifer D.

    2016-01-01

    Electrochemical water oxidation is a major focus of solar energy conversion efforts. A new laboratory experiment has been developed that utilizes real-time, hands-on research to discover catalysts for solar energy conversion. The HARPOON, or Heterogeneous Anodes Rapidly Perused for Oxygen Overpotential Neutralization, experiment allows an array of…

  4. Connecting Biology and Organic Chemistry Introductory Laboratory Courses through a Collaborative Research Project

    Science.gov (United States)

    Boltax, Ariana L.; Armanious, Stephanie; Kosinski-Collins, Melissa S.; Pontrello, Jason K.

    2015-01-01

    Modern research often requires collaboration of experts in fields, such as math, chemistry, biology, physics, and computer science to develop unique solutions to common problems. Traditional introductory undergraduate laboratory curricula in the sciences often do not emphasize connections possible between the various disciplines. We designed an…

  5. Fiberboard and hardboard research at the Forest Products Laboratory : a 50-year summary

    Science.gov (United States)

    Gary C. Myers; J. Dobbin McNatt

    1985-01-01

    Many changes have occurred in the fiber-based panel products industries during the past 50 years. During this timespan the Forest Products Laboratory has conducted a considerable amount of research on processing and product evaluation of fiber-based panel product materials. Unfortunately about 26 percent of this information was never published. completed during this...

  6. A Model Distributive Education Competency Based Learning Laboratory. Final Report. Research Series No. 25.

    Science.gov (United States)

    Strate, James W.; Brorson, Bruce

    The research project focused on the utilization of the model-school store as a distributive education learning laboratory. Objectives were to: (1) Determine the competencies required of teacher-coordinators, (2) determine the instructional materials and equipment needed, (3) develop a model-school store curriculum for secondary education, and (4)…

  7. A laboratory facility for research on wind-driven rain intrusion in building envelope assemblies

    Science.gov (United States)

    Samuel V. Glass

    2010-01-01

    Moisture management is critical for durable, energy-efficient buildings. To address the need for research on wind-driven rain intrusion in wall assemblies, the U.S. Forest Products Laboratory is developing a new facility. This paper describes the underlying principle of this facility and its capabilities.

  8. Fundamental Research in Engineering Education. Student Learning in Industrially Situated Virtual Laboratories

    Science.gov (United States)

    Koretsky, Milo D.; Kelly, Christine; Gummer, Edith

    2011-01-01

    The instructional design and the corresponding research on student learning of two virtual laboratories that provide an engineering task situated in an industrial context are described. In this problem-based learning environment, data are generated dynamically based on each student team's distinct choices of reactor parameters and measurements.…

  9. A method to evaluate performance reliability of individual subjects in laboratory research applied to work settings.

    Science.gov (United States)

    1978-10-01

    This report presents a method that may be used to evaluate the reliability of performance of individual subjects, particularly in applied laboratory research. The method is based on analysis of variance of a tasks-by-subjects data matrix, with all sc...

  10. Artificial Intelligence Research at the Artificial Intelligence Laboratory, Massachusetts Institute of Technology

    OpenAIRE

    Winston, Patrick H.

    1983-01-01

    The primary goal of the Artificial Intelligence Laboratory is to understand how computers can be made to exhibit intelligence. Two corollary goals are to make computers more useful and to understand certain aspects of human intelligence. Current research includes work on computer robotics and vision, expert systems, learning and commonsense reasoning, natural language understanding, and computer architecture.

  11. 2013 Annual Site Environmental Report for Sandia National Laboratories Tonopah Test Range Nevada & Kauai Test Facility Hawaii

    Energy Technology Data Exchange (ETDEWEB)

    Griffith, Stacy Rene [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Agogino, Karen [National Nuclear Security Administration (NNSA), Washington, DC (United States); Li, Jun [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); White, Nancy [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Minitrez, Alexandra [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Avery, Penny [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Bailey-White, Brenda [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Bonaguidi, Joseph [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Catechis, Christopher [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); duMond, Michael [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Eckstein, Joanna [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Evelo, Stacie [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Forston, William [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Herring, III, Allen [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Lantow, Tiffany [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Martinez, Reuben [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Mauser, Joseph [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Miller, Amy [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Miller, Mark [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Payne, Jennifer [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Peek, Dennis [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Reiser, Anita [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Ricketson, Sherry [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Roma, Charles [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Salinas, Stephanie [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Ullrich, Rebecca [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2014-08-01

    Tonopah Test Range (TTR) in Nevada and Kauai Test Facility (KTF) in Hawaii are government-owned, contractor-operated facilities managed and operated by Sandia Corporation (Sandia), a wholly owned subsidiary of Lockheed Martin Corporation. The U.S. Department of Energy (DOE), National Nuclear Security Administration (NNSA), through the Sandia Field Office (SFO), in Albuquerque, New Mexico, administers the contract and oversees contractor operations at TTR and KTF. Sandia manages and conducts operations at TTR in support of the DOE/NNSA’s Weapons Ordnance Program and has operated the site since 1957. Navarro Research and Engineering subcontracts to Sandia in administering most of the environmental programs at TTR. Sandia operates KTF as a rocket preparation launching and tracking facility. This Annual Site Environmental Report summarizes data and the compliance status of the sustainability, environmental protection, and monitoring program at TTR and KTF through Calendar Year 2013. The compliance status of environmental regulations applicable at these sites include state and federal regulations governing air emissions, wastewater effluent, waste management, terrestrial surveillance, Environmental Restoration (ER) cleanup activities, and the National Environmental Policy Act. Sandia is responsible only for those environmental program activities related to its operations. The DOE/NNSA/Nevada Field Office retains responsibility for the cleanup and management of TTR ER sites. Environmental monitoring and surveillance programs are required by DOE Order 231.1B, Environment, Safety, and Health Reporting (DOE 2012).

  12. Fundamental investigations of natural and laboratory generated SAR dose response curves for quartz OSL in the high dose range

    DEFF Research Database (Denmark)

    Timar-Gabor, Alida; Constantin, Daniela; Buylaert, Jan-Pieter

    2015-01-01

    saturation much earlier. Analysis of time resolved spectra indicated similar luminescence lifetimes for both fine and coarse quartz grains, and natural and laboratory generated OSL signals seem to use the same non-dosedependent recombination pathways. The natural signals of a sample with an expected......SAR-OSL investigations on quartz from Romanian loess resulted in non concordant fine and coarse-grain ages for equivalent doses higher than ~100 Gy. The laboratory dose response for both grain sizes is well represented by a sum of two saturating exponential functions, fine and coarse grains...... equivalent dose of 2000e2500 Gy were found to be below the saturation level of the laboratory dose response curve for both grain sizes; this also applied to the luminescence signals measured after >5000 Gy given on top of natural doses. © 2015 Elsevier Ltd. All rights reserved....

  13. High-sulfur coal research at the SIUC (Southern Illinois University at Carbondale) Coal Technology Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    None

    1988-01-01

    Research on high-sulfur coal which is taking place at the Coal Technology Laboratory at Southern Illinois University at Carbondale is divided into four general categories: coal science, coal preparation, coal conversion, and coal utilization. The work in these four areas covers a broad spectrum of high-sulfur coal research from the very fundamental aspects of the coal, through its physical beneficiation and possible conversion, to its ultimate utilization and overall economic modeling. Individual projects are processed separately for the databases.

  14. Energetic materials research and development activities at Sandia National Laboratories supported under DP-10 programs

    Energy Technology Data Exchange (ETDEWEB)

    Ratzel, A.C. III

    1998-09-01

    This report provides summary descriptions of Energetic Materials (EM) Research and Development activities performed at Sandia National Laboratories and funded through the Department of Energy DP-10 Program Office in FY97 and FY98. The work falls under three major focus areas: EM Chemistry, EM Characterization, and EM Phenomenological Model Development. The research supports the Sandia component mission and also Sandia's overall role as safety steward for the DOE Nuclear Weapons Complex.

  15. The research program of the Liquid Scintillation Detector (LSD) in the Mont Blanc Laboratory

    Science.gov (United States)

    Dadykin, V. L.; Yakushev, V. F.; Korchagin, P. V.; Korchagin, V. B.; Malgin, A. S.; Ryassny, F. G.; Ryazhskaya, O. G.; Talochkin, V. P.; Zatsepin, G. T.; Badino, G.

    1985-01-01

    A massive (90 tons) liquid scintillation detector (LSD) has been running since October 1984 in the Mont Blanc Laboratory at a depth of 5,200 hg/sq cm of standard rock. The research program of the experiment covers a variety of topics in particle physics and astrophysics. The performance of the detector, the main fields of research are presented and the preliminary results are discussed.

  16. Data Driven Research at LIS: the Laboratory of Information Systems at UNICAMP

    OpenAIRE

    Medeiros, Claudia Bauzer; Santanchè, André; Madeira, Edmundo R. M.; Martins, Eliane; Magalhâes, Geovane C.; Baranauskas, Maria Cecilia C.; Leite, Neucimar J.; Torres, Ricardo da S.

    2011-01-01

    This article presents an overview of the research conducted at the Laboratory of Information Systems (LIS) at the Institute of Computing, UNICAMP. Its creation, in 1994, was motivated by the need to support data-driven research within multidisciplinary projects involving computer scientists and scientists from other fields. Throughout the years, it has housed projects in many domains - in agriculture, biodiversity, medicine, health, bioinformatics, urban planning, telecommunications, and spor...

  17. Solar energy research at Sandia Laboratories and its effects on health and safety

    Energy Technology Data Exchange (ETDEWEB)

    Young, L.L. III

    1977-10-01

    Various solar energy research and development projects at Sandia Laboratories are discussed with emphasis on the primary health and safety hazard associated with solar concentration systems. This limiting hazard is chorioretinal damage. The unique safety and health hazards associated with solar energy collector and receiver systems cannot be measured yet, but progress is being made rapidly. Research is continuing, especially for eye hazards, with more extensive work planned.

  18. Plant research '79: report of the Michigan State University, Department of Energy, Plant Research Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-01

    Botanical research conducted at MSU during 1979 is described. Areas of study include cell wall biosynthesis, hormonal regulation, responses of plants to environmental stresses, and molecular studies. (ACR)

  19. 1999 Summer Research Program for High School Juniors at the University of Rochester's Laboratory for Laser Energetics

    Energy Technology Data Exchange (ETDEWEB)

    None

    2002-10-09

    oak-B202--During the summer of 1999, 12 students from Rochester-area high schools participated in the Laboratory for Laser Energetics' Summer High School Research Program. The goal of this program is to excite a group of high school students about careers in the areas of science and technology by exposing them to research in a state-of-the-art environment. Too often, students are exposed to ''research'' only through classroom laboratories that have prescribed procedures and predictable results. In LLE's summer program, the students experience all of the trials, tribulations, and rewards of scientific research. By participating in research in a real environment, the students often become more enthusiastic about careers in science and technology. In addition, LLE gains from the contributions of the many highly talented students who are attracted to the program. The students spent most of their time working on their individual research projects with members of LLE's technical staff. The projects were related to current research activities at LLE and covered a broad range of areas of interest including laser modeling, diagnostic development, chemistry, liquid crystal devices, and opacity data visualization. The students, their high schools, their LLE supervisors and their project titles are listed in the table. Their written reports are collected in this volume. The students attended weekly seminars on technical topics associated with LLE's research. Topics this year included lasers, fusion, holography, optical materials, global warming, measurement errors, and scientific ethics. The students also received safety training, learned how to give scientific presentations, and were introduced to LLE's resources, especially the computational facilities. The program culminated with the High School Student Summer Research Symposium on 25 August at which the students presented the results of their research to an audience that

  20. Research of smoothing pseudo-range algorithm by Doppler based on GPS/BD

    Science.gov (United States)

    Kang, Chuanli; Zhou, Yanliu

    2015-12-01

    GNSS (Global Navigation Satellite System) technology not only in the general field of surveying and mapping, geology, mining, water and electricity, and in particular in the field of public security, fire protection, tourism, search and rescue, adventure have been more widely used. These special areas require real-time and high positioning accuracy. Currently, GNSS precision positioning technology has become a hot research direction. This paper introduced an algorithm of smoothing pseudo range by Doppler based GPS/BD to improve GNSS positioning precision. This algorithm decoded the pseudo range data and ephemeris data, and then designed algorithm of smoothing pseudo range by Doppler according principle of Doppler smoothing pseudo range. This algorithm was realized by C++ and proved its efficiency. At last, this algorithm has proved its correctness through calculating and analyzing practical Doppler and pseudo range data, and then a conclusion has been obtained: the Doppler value precision is sub-meter, far better than the pseudo-range accuracy, so that if the two data are combined to calculate position that can help to improve the positioning accuracy.

  1. 2016 Annual Site Environmental report Sandia National Laboratories Tonopah Test Range Nevada & Kaua'i Test Facility Hawai'i.

    Energy Technology Data Exchange (ETDEWEB)

    Salas, Angela Maria [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Griffith, Stacy R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-07-01

    Sandia National Laboratories (SNL) is a multimission laboratory managed and operated by National Technology & Engineering Solutions of Sandia, LLC, a wholly owned subsidiary of Honeywell International Inc., for the U.S. Department of Energy’s (DOE’s), National Nuclear Security Administration (NNSA) under contract DE-NA0003525. The DOE/NNSA Sandia Field Office administers the contract and oversees contractor operations at the SNL, Tonopah Test Range (SNL/TTR) in Nevada and the SNL, Kaua‘i Test Facility (SNL/KTF) in Hawai‘i. SNL personnel manage and conduct operations at SNL/TTR in support of the DOE/NNSA’s Weapons Ordnance Program and have operated the site since 1957. Navarro Research and Engineering personnel perform most of the environmental programs activities at SNL/TTR. The DOE/NNSA/Nevada Field Office retains responsibility for cleanup and management of SNL/TTR Environmental Restoration sites. SNL personnel operate SNL/KTF as a rocket preparation launching and tracking facility. This Annual Site Environmental Report (ASER) summarizes data and the compliance status of sustainability, environmental protection, and monitoring programs at SNL/TTR and SNL/KTF during calendar year 2016. Major environmental programs include air quality, water quality, groundwater protection, terrestrial and biological surveillance, waste management, pollution prevention, environmental restoration, oil and chemical spill prevention, and implementation of the National Environmental Policy Act. This ASER is prepared in accordance with and as required by DOE O 231.1B, Admin Change 1, Environment, Safety, and Health Reporting.

  2. 77 FR 26069 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2012-05-02

    ... June 4, 2012, at L'Enfant Plaza Hotel, and not on June 11-12, 2012. Clinical Research Program will meet... addresses of the hotel and VA Central Office are: L'Enfant Plaza Hotel, 480 L'Enfant Plaza SW., Washington... advice on the scientific quality, budget, safety and mission relevance of investigator-initiated research...

  3. Summer Research Program (1992). Graduate Student Research Program (GSRP) Reports. Volume 10. Wright Laboratory

    Science.gov (United States)

    1992-12-28

    report presents the results of work accomplished during the 8-week AFOSR summer research program at the AARA lab of Wright Patterson Air Force Base...during the 8-week AFOSR summer research pro- gram at the AARA lab of Wright Patterson Air Force Base. The goal of this work is a scheme for detecting

  4. Reducing patient re-identification risk for laboratory results within research datasets.

    Science.gov (United States)

    Atreya, Ravi V; Smith, Joshua C; McCoy, Allison B; Malin, Bradley; Miller, Randolph A

    2013-01-01

    To try to lower patient re-identification risks for biomedical research databases containing laboratory test results while also minimizing changes in clinical data interpretation. In our threat model, an attacker obtains 5-7 laboratory results from one patient and uses them as a search key to discover the corresponding record in a de-identified biomedical research database. To test our models, the existing Vanderbilt TIME database of 8.5 million Safe Harbor de-identified laboratory results from 61 280 patients was used. The uniqueness of unaltered laboratory results in the dataset was examined, and then two data perturbation models were applied-simple random offsets and an expert-derived clinical meaning-preserving model. A rank-based re-identification algorithm to mimic an attack was used. The re-identification risk and the retention of clinical meaning for each model's perturbed laboratory results were assessed. Differences in re-identification rates between the algorithms were small despite substantial divergence in altered clinical meaning. The expert algorithm maintained the clinical meaning of laboratory results better (affecting up to 4% of test results) than simple perturbation (affecting up to 26%). With growing impetus for sharing clinical data for research, and in view of healthcare-related federal privacy regulation, methods to mitigate risks of re-identification are important. A practical, expert-derived perturbation algorithm that demonstrated potential utility was developed. Similar approaches might enable administrators to select data protection scheme parameters that meet their preferences in the trade-off between the protection of privacy and the retention of clinical meaning of shared data.

  5. Argonne National Laboratory High Energy Physics Division semiannual report of research activities, January 1, 1989--June 30, 1989

    Energy Technology Data Exchange (ETDEWEB)

    1989-01-01

    This paper discuss the following areas on High Energy Physics at Argonne National Laboratory: experimental program; theory program; experimental facilities research; accelerator research and development; and SSC detector research and development.

  6. LDRD 2012 Annual Report: Laboratory Directed Research and Development Program Activities

    Energy Technology Data Exchange (ETDEWEB)

    Bookless, William [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2012-12-31

    Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2B dated April 19, 2006. This report provides a detailed look at the scientific and technical activities for each of the LDRD projects funded by BNL in FY2012, as required. In FY2012, the BNL LDRD Program funded 52 projects, 14 of which were new starts, at a total cost of $10,061,292.

  7. LDRD 2015 Annual Report: Laboratory Directed Research and Development Program Activities

    Energy Technology Data Exchange (ETDEWEB)

    Hatton, D. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-12-31

    Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy (DOE) in accordance with DOE Order 413.2B dated April 19, 2006. This report provides a detailed look at the scientific and technical activities for each of the LDRD projects funded by BNL in FY 2015, as required. In FY 2015, the BNL LDRD Program funded 43 projects, 12 of which were new starts, at a total cost of $9.5M.

  8. Creativity in research and development laboratories: A new scale for leader behaviours

    Directory of Open Access Journals (Sweden)

    Vishal Gupta

    2013-06-01

    Full Text Available In this paper, we report an inventory of leader behaviours that can promote creativity among R&D professionals. Specifically, we constructed and quantitatively validated a scale that was previously developed using a qualitative approach. We surveyed 584 scientists from 11 R&D laboratories in India. Exploratory and confirmatory factor analyses of the rating responses disclosed five leader behaviour factors: task-orientation; recognising and inspiring; empowering; team building and developing; and leading by example. Given acceptable evidence for convergent and discriminant validities of the factors, we argue for the use of this scale in future research in and management of creativity in R&D laboratories.

  9. Definition of experiments and instruments for a communication/navigation research laboratory. Volume 2: Experiment selection

    Science.gov (United States)

    1972-01-01

    The selection and definition of candidate experiments and the associated experiment instrumentation requirements are described. Information is presented that addresses the following study objectives: (1) determine specific research and technology needs in the comm/nav field through a survey of the scientific/technical community; (2) develop manned low earth orbit space screening criteria and compile lists of potential candidate experiments; (3) in Blue Book format, define and describe selected candidate experiments in sufficient detail to develop laboratory configuration designs and layouts; and (4) develop experiment time phasing criteria and recommend a payload for sortie can/early laboratory missions.

  10. United States Air Force Summer Research Program - 1993. Volume 5B. Wright Laboratory

    Science.gov (United States)

    1993-12-01

    Elect.ricl Engineering Research, MS Laboratory: AEDC/ Box 1649 Station B Vanderbilt University Vol-Page No: 6- 1 Nashville, TN 37235-0000 Abrate, Serge Field...Laboratory: RL/C3 Electrical Engineering University of Southwestern Lou Vol-Page No: 4- 3 Lafayette, LA 70504-3890 x SFRP Participant Data Hong, Lang ...T. Frey, Ch. Gerber, H.-J. Guntherodt, H.P. Lang , and J. Mannhart, Z. Phys. B 86, 163 (1992) 46. S.J. Pennycook, M.F. Chisholm, D.E. Jesson, R

  11. LDRD 2014 Annual Report: Laboratory Directed Research and Development Program Activities

    Energy Technology Data Exchange (ETDEWEB)

    Hatton, Diane [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-03-01

    Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy (DOE) in accordance with DOE Order 413.2B dated April 19, 2006. This report provides a detailed look at the scientific and technical activities for each of the LDRD projects funded by BNL in FY 2014, as required. In FY 2014, the BNL LDRD Program funded 40 projects, 8 of which were new starts, at a total cost of $9.6M.

  12. Laboratory directed research and development: Annual report to the Department of Energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-01

    As one of the premier scientific laboratories of the DOE, Brookhaven must continuously foster the development of new ideas and technologies, promote the early exploration and exploitation of creative and innovative concepts, and develop new fundable R and D projects and programs. At Brookhaven National Laboratory one such method is through its Laboratory Directed Research and Development Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community, fostering new science and technology ideas, which is a major factor in achieving and maintaining staff excellence and a means to address national needs within the overall mission of the DOE and BNL. The Project Summaries with their accomplishments are described in this report. Aside from leading to new fundable or promising programs and producing especially noteworthy research, they have resulted in numerous publications in various professional and scientific journals and presentations at meetings and forums.

  13. LABORATORY DIRECTED RESEARCH AND DEVELOPMENT ANNUAL REPORT TO THE DEPARTMENT OF ENERGY - DECEMBER 2003

    Energy Technology Data Exchange (ETDEWEB)

    FOX,K.J.

    2003-12-31

    Brookhaven National (BNL) Laboratory is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, under contract with the U. S. Department of Energy. BNL's total annual budget has averaged about $450 million. There are about 3,000 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 41 3.2A, ''Laboratory Directed Research and Development,'' January 8, 2001, and the LDRD Annual Report guidance, updated February 12, 1999. The LDRD Program obtains its funds through the Laboratory overhead pool and operates under the authority of DOE Order 413.2A. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology

  14. LABORATORY DIRECTED RESEARCH AND DEVELOPMENT ANNUAL REPORT TO THE DEPARTMENT OF ENERGY - DECEMBER 2004

    Energy Technology Data Exchange (ETDEWEB)

    FOX,K.J.

    2004-12-31

    Brookhaven National (BNL) Laboratory is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, under contract with the U. S. Department of Energy. BNL's total annual budget has averaged about $460 million. There are about 2,800 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 4 13.2A, ''Laboratory Directed Research and Development,'' January 8, 2001, and the LDRD Annual Report guidance, updated February 12, 1999. The LDRD Program obtains its funds through the Laboratory overhead pool and operates under the authority of DOE Order 413.2A. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology

  15. LABORATORY DIRECTED RESEARCH AND DEVELOPMENT ANNUAL REPORT TO THE DOE - DECEMBER 2001.

    Energy Technology Data Exchange (ETDEWEB)

    FOX,K.J.

    2001-12-01

    Brookhaven National (BNL) Laboratory is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, under contract with the U. S. Department of Energy. BNL's total annual budget has averaged about $450 million. There are about 3,000 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 4 13.2, ''Laboratory Directed Research and Development,'' March 5, 1997, and the LDRD Annual Report guidance, updated February 12, 1999. The LDRD Program obtains its funds through the Laboratory overhead pool and operates under the authority of DOE Order 4 13.2. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology ideas

  16. Blackroom Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Enables evaluation and characterization of materials ranging from the ultraviolet to the longwave infrared (LWIR).DESCRIPTION: The Blackroom Laboratory is...

  17. Correlates of research effort in carnivores: body size, range size and diet matter.

    Directory of Open Access Journals (Sweden)

    Zoe M Brooke

    Full Text Available Given the budgetary restrictions on scientific research and the increasing need to better inform conservation actions, it is important to identify the patterns and causes of biases in research effort. We combine bibliometric information from a literature review of almost 16,500 peer-reviewed publications on a well-known group of 286 species, the Order Carnivora, with global datasets on species' life history and ecological traits to explore patterns in research effort. Our study explores how species' characteristics influenced the degree to which they were studied (measured as the number of publications. We identified a wide variation in intensity of research effort at both Family and Species levels, with some of the least studied being those which may need protection in future. Our findings hint at the complex role of human perspectives in setting research agendas. We found that better-studied species tended to be large-bodied and have a large geographic range whilst omnivory had a negative relationship with research effort. IUCN threat status did not exhibit a strong relationship with research effort which suggests that the conservation needs of individual species are not major drivers of research interest. This work is the first to use a combination of bibliometric analysis and biological data to quantify and interpret gaps in research knowledge across an entire Order. Our results could be combined with other resources, such as Biodiversity Action Plans, to prioritise and co-ordinate future research effort, whilst our methods can be applied across many scientific disciplines to describe knowledge gaps.

  18. Correlates of research effort in carnivores: body size, range size and diet matter.

    Science.gov (United States)

    Brooke, Zoe M; Bielby, Jon; Nambiar, Kate; Carbone, Chris

    2014-01-01

    Given the budgetary restrictions on scientific research and the increasing need to better inform conservation actions, it is important to identify the patterns and causes of biases in research effort. We combine bibliometric information from a literature review of almost 16,500 peer-reviewed publications on a well-known group of 286 species, the Order Carnivora, with global datasets on species' life history and ecological traits to explore patterns in research effort. Our study explores how species' characteristics influenced the degree to which they were studied (measured as the number of publications). We identified a wide variation in intensity of research effort at both Family and Species levels, with some of the least studied being those which may need protection in future. Our findings hint at the complex role of human perspectives in setting research agendas. We found that better-studied species tended to be large-bodied and have a large geographic range whilst omnivory had a negative relationship with research effort. IUCN threat status did not exhibit a strong relationship with research effort which suggests that the conservation needs of individual species are not major drivers of research interest. This work is the first to use a combination of bibliometric analysis and biological data to quantify and interpret gaps in research knowledge across an entire Order. Our results could be combined with other resources, such as Biodiversity Action Plans, to prioritise and co-ordinate future research effort, whilst our methods can be applied across many scientific disciplines to describe knowledge gaps.

  19. Semiconductor Electrical Measurements Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Semiconductor Electrical Measurements Laboratory is a research laboratory which complements the Optical Measurements Laboratory. The laboratory provides for Hall...

  20. 76 FR 66367 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2011-10-26

    ...... December 14, 2011... The Sheraton Crystal City. The addresses of the hotel and VA Central Office are: The... quality, budget, safety and mission relevance of investigator-initiated research proposals submitted for...

  1. Field and laboratory notes on instream research - Research and Development of New Marking and Monitoring Technologies

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This project addresses how to expand the current fish-tracking technologies to enable the fisheries community to successfully carry out the actions, research, and...

  2. Savannah River Ecology Laboratory. Annual technical progress report of ecological research, period ending July 31, 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-07-31

    The Savannah River Ecology Laboratory (SREL) is a research unit of the University of Georgia (UGA) that is managed in conjunction with the University`s Institute of Ecology. The laboratory`s overall mission is to acquire and communicate knowledge of ecological processes and principles. SREL conducts basic and applied ecological research, as well as education and outreach programs, under an M&O contract with the US Department of Energy at the Savannah River Site. Significant accomplishments were made during the year ending July 31, 1994 in the areas of research, education and service. Reviewed in this document are research projects in the following areas: Environmental Operations Support (impacted wetlands, streams, trace organics, radioecology, database synthesis, wild life studies, zooplankton, safety and quality assurance); wood stork foraging and breeding ecology; defence waste processing facility; environmental risk assessment (endangered species, fish, ash basin studies); ecosystem alteration by chemical pollutants; wetlands systems; biodiversity on the SRS; Environmental toxicology; environmental outreach and education; Par Pond drawdown studies in wildlife and fish and metals; theoretical ecology; DOE-SR National Environmental Research Park; wildlife studies. Summaries of educational programs and publications are also give.

  3. Adaptive Training and Education Research at the US Army Research Laboratory: Bibliography (2013-2015)

    Science.gov (United States)

    2016-03-01

    education research program. This includes journal articles, technical reports, and conference papers produced by ARL employees and contractors to support...research program. The bibliography includes references for journal articles, technical reports, and conference papers produced by ARL employees and...Spain. Pacquette L, Rowe J, Baker R, Mott B, Lester J, DeFalco J, Brawner K, Sottilare R, Georgoulas V. Sensor-free or sensor-full: a comparison of

  4. Air Force Research Laboratory Warfighter Readiness Research Division Participation in the 2008 IITSEC

    Science.gov (United States)

    2008-12-15

    engagement zones. Alternatively, the TAWS program could be stripped to a modular weather service and act as a “TAWS on demand.” CGF software would request...methods for the present study. Figure 1. Noldus observed behavior chart. The Present Study During the spring 2008 semester at ASU , 17...research possible and for their continued support of the AFRL/ ASU research partnership. The authors would also like to thank Mr. Harry K. Pedersen for

  5. Pacific Northwest Laboratory annual report for 1990 to the DOE Office of Energy Research

    Energy Technology Data Exchange (ETDEWEB)

    Park, J. F.; Kreml, S. A.; Wildung, R. E.; Hefty, M. G.; Perez, D. A.; Chase, K. K.; Elderkin, C. E.; Owczarski, E. L.; Toburen, L. H.; Parnell, K. A.; Faust, L. G.; Moraski, R. V.; Selby, J. M.; Hilliard, D. K.; Tenforde, T. S.

    1991-02-01

    This report summarizes progress in the environmental sciences research conducted by Pacific Northwest Laboratory (PNL) for the Office of Health and Environment Research in FY 1990. Research is directed toward developing the knowledge needed to guide government policy and technology development for two important environmental problems: environmental restoration and global change. The report is organized by major research areas contributing to resolution of these problems. Additional sections summarize exploratory research, educational institutional interactions, technology transfer, and publications. The PNL research program continues make contributions toward defining and quantifying processes that effect the environment at the local, regional, and global levels. Each research project forms a component in an integrated laboratory, intermediate-scale, and field approach designed to examine multiple phenomena at increasing levels of complexity. This approach is providing system-level insights into critical environmental processes. University liaisons continue to be expanded to strengthen the research and to use PNL resources to train the scientists needed to address long-term environmental problems.

  6. Embry-Riddle Aeronautical University multispectral sensor and data fusion laboratory: a model for distributed research and education

    Science.gov (United States)

    McMullen, Sonya A. H.; Henderson, Troy; Ison, David

    2017-05-01

    The miniaturization of unmanned systems and spacecraft, as well as computing and sensor technologies, has opened new opportunities in the areas of remote sensing and multi-sensor data fusion for a variety of applications. Remote sensing and data fusion historically have been the purview of large government organizations, such as the Department of Defense (DoD), National Aeronautics and Space Administration (NASA), and National Geospatial-Intelligence Agency (NGA) due to the high cost and complexity of developing, fielding, and operating such systems. However, miniaturized computers with high capacity processing capabilities, small and affordable sensors, and emerging, commercially available platforms such as UAS and CubeSats to carry such sensors, have allowed for a vast range of novel applications. In order to leverage these developments, Embry-Riddle Aeronautical University (ERAU) has developed an advanced sensor and data fusion laboratory to research component capabilities and their employment on a wide-range of autonomous, robotic, and transportation systems. This lab is unique in several ways, for example, it provides a traditional campus laboratory for students and faculty to model and test sensors in a range of scenarios, process multi-sensor data sets (both simulated and experimental), and analyze results. Moreover, such allows for "virtual" modeling, testing, and teaching capability reaching beyond the physical confines of the facility for use among ERAU Worldwide students and faculty located around the globe. Although other institutions such as Georgia Institute of Technology, Lockheed Martin, University of Dayton, and University of Central Florida have optical sensor laboratories, the ERAU virtual concept is the first such lab to expand to multispectral sensors and data fusion, while focusing on the data collection and data products and not on the manufacturing aspect. Further, the initiative is a unique effort among Embry-Riddle faculty to develop multi

  7. Definition of experiments and instruments for a communication/navigation research laboratory. Volume 1: Executive summary

    Science.gov (United States)

    1972-01-01

    This study was undertaken to develop conceptual designs for a manned, space shuttle sortie mission laboratory capable of supporting a wide variety of experiments in conjunction with communications and navigation research. This space/laboratory would be one in which man may effectively increase experiment efficiency by certain observations, modifications, setup, calibration, and limited maintenance steps. In addition, man may monitor experiment progress and perform preliminary data evaluation to verify proper equipment functioning and may terminate or redirect experiments to obtain the most desirable end results. The flexibility and unique capabilities of man as an experimenter in such a laboratory will add greatly to the simplification of space experiments and this provides the basis for commonality in many of the supportive subsystems, thus reaping the benefits of reusability and reduced experiment costs. For Vol. 4, see N73-19268.

  8. LDRD 2016 Annual Report: Laboratory Directed Research and Development Program Activities

    Energy Technology Data Exchange (ETDEWEB)

    Hatton, D. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2017-03-31

    Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy (DOE) in accordance with DOE Order 413.2C dated October 22, 2015. This report provides a detailed look at the scientific and technical activities for each of the LDRD projects funded by BNL in FY 2016, as required. In FY 2016, the BNL LDRD Program funded 48 projects, 21 of which were new starts, at a total cost of $11.5M. The investments that BNL makes in its LDRD program support the Laboratory’s strategic goals. BNL has identified four Critical Outcomes that define the Laboratory’s scientific future and that will enable it to realize its overall vision. Two operational Critical Outcomes address essential operational support for that future: renewal of the BNL campus; and safe, efficient laboratory operations.

  9. Publications and geothermal sample library facilities of the Earth Science Laboratory, University of Utah Research Institute

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Phillip M.; Ruth, Kathryn A.; Langton, David R.; Bullett, Michael J.

    1990-03-30

    The Earth Science Laboratory of the University of Utah Research Institute has been involved in research in geothermal exploration and development for the past eleven years. Our work has resulted in the publication of nearly 500 reports, which are listed in this document. Over the years, we have collected drill chip and core samples from more than 180 drill holes in geothermal areas, and most of these samples are available to others for research, exploration and similar purposes. We hope that scientists and engineers involved in industrial geothermal development will find our technology transfer and service efforts helpful.

  10. Research Applications and Capabilities of the NASA/Army Rotorcraft Aircrew Systems Concepts Airborne Laboratory (RASCAL)

    Science.gov (United States)

    Aiken, Edwin W.; Jacobsen, Robert A.; Hindson, William S.

    1996-01-01

    The Rotorcraft Aircrew Systems Concepts Airborne Laboratory (RASCAL) is a UH-60 Black Hawk helicopter that is being modified by NASA and the US Army for flight systems research. The principal systems that are being installed in the aircraft are a Helmet-Mounted Display (HMD) and associated imaging systems, and a programmable full-authority Research Flight Control System (RFCS). In addition, comprehensive instrumentation of both the rigid body of the helicopter and the rotor system is provided. This paper describes the design features of this modern rotorcraft in-flight simulation facility and their current state of development. A brief description of initial research applications is included.

  11. Exploratory Research and Development Fund, FY 1990. Report on Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1992-05-01

    The Lawrence Berkeley Laboratory Exploratory R&D Fund FY 1990 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of an Exploratory R&D Fund (ERF) planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The research areas covered in this report are: Accelerator and fusion research; applied science; cell and molecular biology; chemical biodynamics; chemical sciences; earth sciences; engineering; information and computing sciences; materials sciences; nuclear science; physics and research medicine and radiation biophysics.

  12. The Hawaii Undersea Research Laboratory's 25th Anniversary Expedition to the South Pacific

    Science.gov (United States)

    Smith, J. R.; Wiltshire, J. C.; Malahoff, A.

    2005-12-01

    The Hawaii Undersea Research Laboratory (HURL) was established by NOAA at the University of Hawaii 25 years ago as part of its National Undersea Research Program. HURL's mission is to study deep water marine processes in the Pacific Ocean through a competitive proposal and review process. The dual Pisces IV and Pisces V 2000-meter manned submersibles, an RCV-150 1000-meter ROV, and multibeam equipped support ship R/V Ka'imikai-o-Kanaloa ( KoK) were largely acquired from the petroleum industry then adapted and upgraded to carry out cutting edge scientific expeditions. These studies range from active submarine volcanoes, delicate precious coral gardens, endangered marine mammal and fisheries management, to engineering surveys and deployment of observatory systems. HURL successfully completed a major 5-month expedition to the South Pacific during March-August 2005, working in the waters of New Zealand, Tonga, American Samoa, and the U.S. Line Islands covering a distance of nearly 14,500 nautical miles. This mission was significant in both the scientific merit and scope of operations, consisting of 8 different cruise legs at 21 study sites, with 12 chief and co-chief scientists, 58 total science team participants, and completing 61 out of 56 scheduled Pisces science dives, 17 ROV dives, 5 multibeam survey areas, 6 CTD rosette deployments, and 7 instrument mooring recoveries. The $3.5 million expedition was funded by an international partnership with New Zealand agencies (GNS & NIWA) and the University of Kiel in Germany along with the NOAA Office of Exploration and National Undersea Research Program. While most of the individual cruise legs focused on active submarine volcanoes of the Tonga-Kermadec Islands Arc and the Samoan hot spot chain with their hydrothermal systems and associated biological communities, others concentrated on marine protected areas including those of American Samoa and the remote atolls of the Line Islands of the Central Pacific. These studies

  13. Recent non-linear radar research at the Army Research Laboratory

    Science.gov (United States)

    Gallagher, Kyle A.; Mazzaro, Gregory J.; Martone, Anthony F.; Sherbondy, Kelly D.; Narayanan, Ram M.

    2017-05-01

    Nonlinear radar has proven to be a viable means of detecting devices that contain electrical nonlinearities. Electrical nonlinearities are present in dissimilar metals, metal to oxide junctions, semiconductors and more. This paper presents a linear and nonlinear synthetic aperture radar (SAR) system capable of imaging linear and nonlinear targets. The system creates images using data collected from a fixed 16 channel receiver with a single transmitter. A custom 16:1 switching network was developed to collect the SAR data from a 16 antenna receive array. SAR images presented show a nonlinear target placed directly on the ground and imaged in multiple range and cross-range locations. Data is also presented showing the clutter rejection properties of nonlinear radar. Images show that the harmonic radar is able to ignore the strong linear response from a corner reflector, while retaining the nonlinear response from a target.

  14. Laboratory directed research and development. FY 1991 program activities: Summary report

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-15

    The purposes of Argonne`s Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory`s R&D capabilities, and further the development of its strategic initiatives. Among the aims of the projects supported by the Program are establishment of engineering ``proof-of-principle``; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these project are closely associated with major strategic thrusts of the Laboratory as described in Argonne`s Five Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne. Areas of emphasis are (1) advanced accelerator and detector technology, (2) x-ray techniques in biological and physical sciences, (3) advanced reactor technology, (4) materials science, computational science, biological sciences and environmental sciences. Individual reports summarizing the purpose, approach, and results of projects are presented.

  15. Prevalence of occupational allergy in medical researchers exposed to laboratory animals.

    Science.gov (United States)

    Muzembo, Basilua Andre; Eitoku, Masamitsu; Inaoka, Yuta; Oogiku, Makiko; Kawakubo, Mitomo; Tai, Ryuta; Takechi, Momoko; Hirabayashi, Ken-ichi; Yoshida, Naofumi; Ngatu, Nlandu Roger; Hirota, Ryoji; Sandjaya, Bernardus; Suganuma, Narufumi

    2014-01-01

    Allergy to laboratory animals is a well known occupational hazard and remains a health concern for individuals in contact with lab animals. This study evaluates the prevalence of allergy symptoms among medical researchers exposed to laboratory animals. We analyzed data from a cross-sectional survey, involving subjects (n=169, 21-59 yr), working in Kochi Medical School, Japan. They were asked to fill out a questionnaire to evaluate symptoms related to contact with laboratory animals. The overall response rate was 86.2%. The prevalence of laboratory animal allergy was 17.6%. The symptoms most reported were allergic rhino-conjunctivitis and asthma. A small number of the subjects received education on the allergy issue and 62.5% of subjects with an allergy to laboratory animals claimed to have atopy. Protection from animal allergens should be a high priority for institutions using lab animals; providing continuous education to animal handlers would be meaningful to reduce and control exposure.

  16. Cyclotron laboratory of the Institute for Nuclear Research and Nuclear Energy

    Science.gov (United States)

    Tonev, D.; Goutev, N.; Georgiev, L. S.

    2016-06-01

    An accelerator laboratory is presently under construction in Sofia at the Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences. The laboratory will use a TR24 type of cyclotron, which provides a possibility to accelerate a proton beam with an energy of 15 to 24 MeV and current of up to 0.4 mA. An accelerator with such parameters allows to produce a large variety of radioisotopes for development of radiopharmaceuticals. The most common radioisotopes that could be produced with such a cyclotron are PET isotopes like: 11C, 13N, 15O, 18F, 124I, 64Cu, 68Ge/68Ga, and SPECT isotopes like: 123I, 111In, 67Ga, 57Co, 99m Tc. Our aim is to use the cyclotron facility for research in the fields of radiopharmacy, radiochemistry, radiobiology, nuclear physics, solid state physics, applied research, new materials and for education in all these fields including nuclear energy. The building of the laboratory will be constructed nearby the Institute for Nuclear Research and Nuclear Energy and the cyclotron together with all the equipment needed will be installed there.

  17. Human Toxocariasis: Prevalence and Factors Associated with Biosafety in Research Laboratories

    Science.gov (United States)

    Mattos, Gabriela Torres; dos Santos, Paula Costa; Telmo, Paula de Lima; Berne, Maria Elisabeth Aires; Scaini, Carlos James

    2016-01-01

    Human toxocariasis is a neglected parasitic disease worldwide. Researchers studying this disease use infectious strains of Toxocara for experiments. Health workers are at risk in the course of their daily routine and must adhere to biosafety standards while carrying out the activities. Researchers on biosafety concerning working with these parasites are insufficient. The aim of this study was to determine the rate of seroprevalence of Toxocara species among health-care research laboratory workers (professors, technicians, and students), and to investigate the risk factors of Toxocara infection associated with laboratory practices. This cross-sectional study involved 74 researchers at two federal universities in southern Brazil from February 2014 to February 2015; 29 researchers manipulated infective strains of Toxocara canis (test group) and 45 did not (control group). Serum samples were examined using enzyme-linked immunosorbent assay. Epidemiological data were obtained via a questionnaire containing information about laboratory routine, eating behavior, and contact with dogs. The seroprevalence of anti-T. canis IgG was 14.9% (11/74; 13.8% [4/29] in the test group and 15.6% [7/45] in the control group). Most individuals in the test group correctly understood the primary mode of infection; however, 13.8% did not use gloves while manipulating T. canis eggs. Knowledge of biosafety must be well understood by health-care professionals doing laboratory work with biological agents. To our knowledge, this is the first study to investigate the rate of seroprevalence of IgG against Toxocara spp. among professionals and students who handle infective forms of the nematode T. canis. PMID:27698276

  18. 77 FR 20489 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2012-04-04

    ... Plaza Hotel. Oncology-A June 14-15, 2012. Sheraton Suites--Old Town Alexandria. Nephrology June 15, 2012.... The addresses of the hotel and VA Central Office are: L'Enfant Plaza Hotel, 480 L'Enfant Plaza SW... advice on the scientific quality, budget, safety and mission relevance of investigator-initiated research...

  19. Strengthening LLNL Missions through Laboratory Directed Research and Development in High Performance Computing

    Energy Technology Data Exchange (ETDEWEB)

    Willis, D. K. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-12-01

    High performance computing (HPC) has been a defining strength of Lawrence Livermore National Laboratory (LLNL) since its founding. Livermore scientists have designed and used some of the world’s most powerful computers to drive breakthroughs in nearly every mission area. Today, the Laboratory is recognized as a world leader in the application of HPC to complex science, technology, and engineering challenges. Most importantly, HPC has been integral to the National Nuclear Security Administration’s (NNSA’s) Stockpile Stewardship Program—designed to ensure the safety, security, and reliability of our nuclear deterrent without nuclear testing. A critical factor behind Lawrence Livermore’s preeminence in HPC is the ongoing investments made by the Laboratory Directed Research and Development (LDRD) Program in cutting-edge concepts to enable efficient utilization of these powerful machines. Congress established the LDRD Program in 1991 to maintain the technical vitality of the Department of Energy (DOE) national laboratories. Since then, LDRD has been, and continues to be, an essential tool for exploring anticipated needs that lie beyond the planning horizon of our programs and for attracting the next generation of talented visionaries. Through LDRD, Livermore researchers can examine future challenges, propose and explore innovative solutions, and deliver creative approaches to support our missions. The present scientific and technical strengths of the Laboratory are, in large part, a product of past LDRD investments in HPC. Here, we provide seven examples of LDRD projects from the past decade that have played a critical role in building LLNL’s HPC, computer science, mathematics, and data science research capabilities, and describe how they have impacted LLNL’s mission.

  20. Ernest Orlando Berkeley National Laboratory - Fundamental and applied research on lean premixed combustion

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Robert K.

    1999-07-07

    Ernest Orland Lawrence Berkeley National Laboratory (Berkeley Lab) is the oldest of America's national laboratories and has been a leader in science and engineering technology for more than 65 years, serving as a powerful resource to meet Us national needs. As a multi-program Department of Energy laboratory, Berkeley Lab is dedicated to performing leading edge research in the biological, physical, materials, chemical, energy, environmental and computing sciences. Ernest Orlando Lawrence, the Lab's founder and the first of its nine Nobel prize winners, invented the cyclotron, which led to a Golden Age of particle physics and revolutionary discoveries about the nature of the universe. To this day, the Lab remains a world center for accelerator and detector innovation and design. The Lab is the birthplace of nuclear medicine and the cradle of invention for medical imaging. In the field of heart disease, Lab researchers were the first to isolate lipoproteins and the first to determine that the ratio of high density to low density lipoproteins is a strong indicator of heart disease risk. The demise of the dinosaurs--the revelation that they had been killed off by a massive comet or asteroid that had slammed into the Earth--was a theory developed here. The invention of the chemical laser, the unlocking of the secrets of photosynthesis--this is a short preview of the legacy of this Laboratory.

  1. Pacific Northwest Laboratory annual report for 1991 to the DOE Office of Energy Research. Part 3, Atmospheric and climate research

    Energy Technology Data Exchange (ETDEWEB)

    1992-05-01

    Within the US Department of Energy`s (DOE`s) Office of Health and Environmental Research (OHER), the atmospheric sciences and carbon dioxide research programs are part of the Environmental Sciences Division (ESD). One of the central missions of the division Is to provide the DOE with scientifically defensible information on the local, regional, and global distributions of energy-related pollutants and their effects on climate. This information is vital to the definition and Implementation of a sound national energy strategy. This volume reports on the progress and status of all OHER atmospheric science and climate research projects at the Pacific Northwest Laboratory (PNL). Research at PNL provides basic scientific underpinnings to DOE`s program of global climate research. Research projects within the core carbon dioxide and ocean research programs are now integrated with those in the Atmospheric Radiation Measurements (ARM), the Computer Hardware, Advanced Mathematics and Model Physics (CHAMMP), and quantitative links programs to form DOEs contribution to the US Global Change Research Program. Climate research in the ESD has the common goal of improving our understanding of the physical, chemical, biological, and social processes that influence the Earth system so that national and international policymaking relating to natural and human-induced changes in the Earth system can be given a firm scientific basis. This report describes the progress In FY 1991 in each of these areas.

  2. Tools and Methods to Create Scenarios for Experimental Research in the Network Science Research Laboratory (NSRL)

    Science.gov (United States)

    2015-12-01

    among the nodes, you can choose to create more wireless networks by adding more clouds, or you can create a wired connection between 2 nodes. To make...traditional wireless networking challenges as well as more general network science research issues. NSRL is capable of doing this by providing a...the .eel file through EMANE. Click on the square blue Ethernet hub on the left panel. Select the cloud (which is a wireless local area network [LAN

  3. Developing laboratory research techniques for an ongoing research program in a high school classroom

    Science.gov (United States)

    Adornato, Philip

    Incorporating research into a high school classroom is an excellent way to teach students fundamental concepts in science. One program that incorporates this approach is the Waksman Student Scholar Program (WSSP), which allows high school students, teachers and Rutgers professors to work side by side on an ongoing molecular biology research program. Students in the program first isolated plasmid clones from bacteria that contain cDNA fragments of genes from the Brine Shrimp Artemia franciscana. They then determined the size of the DNA by performing molecular biology experiments. Students then analyzed the DNA sequence and after review from WSSP staff and high school teachers, the student's sequences were published in the National Center for Biotechnology Information (NCBI) database. This was often the last step in the project the students performed. However, if the project were being conducted in a research lab instead of a high school, the cDNA clone would often be further analyzed. In the past, safety, convenience, and affordability have limited the availability of these experiments in a high school setting. Although additional bioinformatic experiments could easily be performed in the high school, there is a strong need for additional "wet lab" experiments to keep the students engaged and motivated to work on the project. I have worked on developing three experimental modules that can be performed in a high school setting. These experiments were tested with the students and teachers of the WSSP. This work will expand the scope of experiments that can be performed in a high school environment.

  4. The Laboratory Course Assessment Survey: A Tool to Measure Three Dimensions of Research-Course Design

    Science.gov (United States)

    Corwin, Lisa A.; Runyon, Christopher; Robinson, Aspen; Dolan, Erin L.

    2015-01-01

    Course-based undergraduate research experiences (CUREs) are increasingly being offered as scalable ways to involve undergraduates in research. Yet few if any design features that make CUREs effective have been identified. We developed a 17-item survey instrument, the Laboratory Course Assessment Survey (LCAS), that measures students’ perceptions of three design features of biology lab courses: 1) collaboration, 2) discovery and relevance, and 3) iteration. We assessed the psychometric properties of the LCAS using established methods for instrument design and validation. We also assessed the ability of the LCAS to differentiate between CUREs and traditional laboratory courses, and found that the discovery and relevance and iteration scales differentiated between these groups. Our results indicate that the LCAS is suited for characterizing and comparing undergraduate biology lab courses and should be useful for determining the relative importance of the three design features for achieving student outcomes. PMID:26466990

  5. The Era of International Space Station Research: Discoveries and Potential of an Unprecedented Laboratory in Space

    Science.gov (United States)

    Robinson, Julie A.

    2011-01-01

    The assembly of the International Space Station was completed in early 2011. Its largest research instrument, the Alpha Magnetic Spectrometer is planned for launch in late April. Unlike any previous laboratory in space, the ISS offers a long term platform where scientists can operate experiments rapidly after developing a new research question, and extend their experiments based on early results. This presentation will explain why having a laboratory in orbit is important for a wide variety of experiments that cannot be done on Earth. Some of the most important results from early experiments are already having impacts in areas such as health care, telemedicine, and disaster response. The coming decade of full utilization offers the promise of new understanding of the nature of physical and biological processes and even of matter itself.

  6. RIPOSTE: a framework for improving the design and analysis of laboratory-based research.

    Science.gov (United States)

    Masca, Nicholas Gd; Hensor, Elizabeth Ma; Cornelius, Victoria R; Buffa, Francesca M; Marriott, Helen M; Eales, James M; Messenger, Michael P; Anderson, Amy E; Boot, Chris; Bunce, Catey; Goldin, Robert D; Harris, Jessica; Hinchliffe, Rod F; Junaid, Hiba; Kingston, Shaun; Martin-Ruiz, Carmen; Nelson, Christopher P; Peacock, Janet; Seed, Paul T; Shinkins, Bethany; Staples, Karl J; Toombs, Jamie; Wright, Adam Ka; Teare, M Dawn

    2015-05-07

    Lack of reproducibility is an ongoing problem in some areas of the biomedical sciences. Poor experimental design and a failure to engage with experienced statisticians at key stages in the design and analysis of experiments are two factors that contribute to this problem. The RIPOSTE (Reducing IrreProducibility in labOratory STudiEs) framework has been developed to support early and regular discussions between scientists and statisticians in order to improve the design, conduct and analysis of laboratory studies and, therefore, to reduce irreproducibility. This framework is intended for use during the early stages of a research project, when specific questions or hypotheses are proposed. The essential points within the framework are explained and illustrated using three examples (a medical equipment test, a macrophage study and a gene expression study). Sound study design minimises the possibility of bias being introduced into experiments and leads to higher quality research with more reproducible results.

  7. Implementation of Current Good Manufacturing Practices in a small research laboratory setting.

    Science.gov (United States)

    Keller, C D; Taulbee, S M

    1995-03-01

    The Current Good Manufacturing Practice (cGMP) for Finished Pharmaceuticals as found in 21 CFR 211 is specifically geared to the regulation of drug-manufacturing processes in industry. However, under some circumstances, it becomes necessary to apply the regulation to manufacturing operations in a research laboratory setting. Application of the regulations in such a setting requires management commitment, cooperation between QA/QC and technical staff, patience, creativity, and an understanding of the spirit behind the letter of the law. Breaking down the regulations into their fundamental parts gives insight into the intent of the regulations and aids in their application. This article will outline our experience in applying the cGMP in a research laboratory setting.

  8. Promoting ergonomics in Algeria: activities of "the research and training laboratory" in the University of Oran.

    Science.gov (United States)

    Mebarki, Bouhafs; El-Bachir, Tebboune Cheikh

    2012-01-01

    The growing need in Algeria to develop ergonomics knowledge and practice in industry was behind the initiative to develop a training and research project within the ergonomics laboratory at Oran University. Since 2005 the laboratory team is running an academic option master in work design and ergonomics. The evaluation of the academic master in 2010 revealed the acute need of the local industry for professional competences in ergonomic and work psychology. A professional training master program in "ergonomics & work psychology" was then developed in partnership with local industry, five European Universities and six Universities from three Maghreb countries. Research projects were initiated around the two training programs, in conjunction with a number of ergonomics dissemination and promotion activities. Preliminary results of the project are presented and discussed in relation to the local context, and in the light of similar cases in Industrially Developing Countries.

  9. Sandia National Laboratories, Tonopah Test Range Askania Tower (Building 02-00): Photographs and Written Historical and Descriptive Data

    Energy Technology Data Exchange (ETDEWEB)

    Ullrich, Rebecca A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Corporate Archives and History Program

    2017-08-01

    The Askania Tower (Building 02-00) was built in 1956 as part of the first wave of construction at the newly established Tonopah Test Range (TTR). Located at Station 2, near the primary target area at the range, the tower was one of the first four built to house Askania phototheodolites used in tracking test units dropped from aircraft. This report includes historical information, architectural information, sources of information, project information, maps, blueprints, and photographs.

  10. AirSTAR Hardware and Software Design for Beyond Visual Range Flight Research

    Science.gov (United States)

    Laughter, Sean; Cox, David

    2016-01-01

    The National Aeronautics and Space Administration (NASA) Airborne Subscale Transport Aircraft Research (AirSTAR) Unmanned Aerial System (UAS) is a facility developed to study the flight dynamics of vehicles in emergency conditions, in support of aviation safety research. The system was upgraded to have its operational range significantly expanded, going beyond the line of sight of a ground-based pilot. A redesign of the airborne flight hardware was undertaken, as well as significant changes to the software base, in order to provide appropriate autonomous behavior in response to a number of potential failures and hazards. Ground hardware and system monitors were also upgraded to include redundant communication links, including ADS-B based position displays and an independent flight termination system. The design included both custom and commercially available avionics, combined to allow flexibility in flight experiment design while still benefiting from tested configurations in reversionary flight modes. A similar hierarchy was employed in the software architecture, to allow research codes to be tested, with a fallback to more thoroughly validated flight controls. As a remotely piloted facility, ground systems were also developed to ensure the flight modes and system state were communicated to ground operations personnel in real-time. Presented in this paper is a general overview of the concept of operations for beyond visual range flight, and a detailed review of the airborne hardware and software design. This discussion is held in the context of the safety and procedural requirements that drove many of the design decisions for the AirSTAR UAS Beyond Visual Range capability.

  11. Faculty and Student Teams and National Laboratories: Expanding the Reach of Research Opportunities and Workforce Development

    Energy Technology Data Exchange (ETDEWEB)

    Blackburn,N.; White, K.; Stegman, M.

    2009-08-05

    The Faculty and Student Teams (FaST) Program, a cooperative effort between the US Department of Energy (DOE) Office of Science and the National Science Foundation (NSF), brings together collaborative research teams composed of a researcher at Brookhaven National Laboratory, and a faculty member with two or three undergraduate students from a college or university. Begun by the Department of Energy in 2000 with the primary goal of building research capacity at a faculty member's home institution, the FaST Program focuses its recruiting efforts on faculty from colleges and universities with limited research facilities and those institutions that serve populations under-represented in the fields of science, engineering and technology, particularly women and minorities. Once assembled, a FaST team spends a summer engaged in hands-on research working alongside a laboratory scientist. This intensely collaborative environment fosters sustainable relationships between the faulty members and BNL that allow faculty members and their BNL colleagues to submit joint proposals to federal agencies, publish papers in peer-reviewed journals, reform local curriculum, and develop new or expand existing research labs at their home institutions.

  12. Institutional training programs for research personnel conducted by laboratory-animal veterinarians.

    Science.gov (United States)

    Dyson, Melissa C; Rush, Howard G

    2012-01-01

    Research institutions are required by federal law and national standards to ensure that individuals involved in animal research are appropriately trained in techniques and procedures used on animals. Meeting these requirements necessitates the support of institutional authorities; policies for the documentation and enforcement of training; resources to support and provide training programs; and high-quality, effective educational material. Because of their expertise, laboratory-animal veterinarians play an essential role in the design, implementation, and provision of educational programs for faculty, staff, and students in biomedical research. At large research institutions, provision of a training program for animal care and use personnel can be challenging because of the animal-research enterprise's size and scope. At the University of Michigan (UM), approximately 3,500 individuals have direct contact with animals used in research. We describe a comprehensive educational program for animal care and use personnel designed and provided by laboratory-animal veterinarians at UM and discuss the challenges associated with its implementation.

  13. Law in the laboratory a guide to the ethics of federally funded science research

    CERN Document Server

    Charrow, Robert P

    2010-01-01

    The National Institutes of Health and the National Science Foundation together fund more than $40 billon of research annually in the United States and around the globe. These large public expenditures come with strings, including a complex set of laws and guidelines that regulate how scientists may use NIH and NSF funds, how federally funded research may be conducted, and who may have access to or own the product of the research. Until now, researchers have had little instruction on the nature of these laws and how they work. But now, with Robert P. Charrow’s Law in the Laboratory, they have a readable and entertaining introduction to the major ethical and legal considerations pertaining to research under the aegis of federal science funding. For any academic whose position is grant funded, or for any faculty involved in securing grants, this book will be an essential reference manual. And for those who want to learn how federal legislation and regulations affect laboratory research, Charrow’s primer wil...

  14. NASA Glenn Research Center's Fuel Cell Stack, Ancillary and System Test and Development Laboratory

    Science.gov (United States)

    Loyselle, Patricia L.; Prokopius, Kevin P.; Becks, Larry A.; Burger, Thomas H.; Dick, Joseph F.; Rodriguez, George; Bremenour, Frank; Long, Zedock

    2011-01-01

    At the NASA Glenn Research Center, a fully operational fuel cell test and evaluation laboratory is available which is capable of evaluating fuel cell components and systems for future NASA missions. Components and subsystems of various types can be operated and monitored under a variety of conditions utilizing different reactants. This fuel cell facility can test the effectiveness of various component and system designs to meet NASA's needs.

  15. Adapting and Using Scrum in a Software Research and Development Laboratory

    Directory of Open Access Journals (Sweden)

    LIMA, I. R.

    2012-06-01

    Full Text Available Agile software development has gained importance in the industry because of its approach on the issues of human agility and return on investment. This paper shows how Scrum agile software project management methodology has been deployed and adapted to the model of software project management of a research and development laboratory. As a result of this deployment, experiences and lessons learned in seven real projects developed by the authors are reported.

  16. US Army Research Laboratory and University of Notre Dame Distributed Sensing: Software Overview

    Science.gov (United States)

    2017-09-01

    Software Overview by Neal Tesny and Daniel T Galanos Approved for public release; distribution is unlimited. NOTICES...US Army Research Laboratory and University of Notre Dame Distributed Sensing: Software Overview by Neal Tesny Sensors and Electron Devices...Sensing: Software Overview 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Neal Tesny and Daniel T Galanos 5d

  17. Calibration of the ARL (Aeronautical Research Laboratories) Rain and Icing Facility.

    Science.gov (United States)

    1987-01-01

    Australian Airlines, Library Qantas Airways Limited Gas & Fuel Corporation of Vic., Manager Scientific Services~SEC of Vic., Herman Research Laboratory... limited resources available and the priority of other tasks it is not considered to be essential for efficient use of the facility. ACrnW ur ORKmf The...Yhis damnint "WY be NAMA*CD in catalogues and awrenss services available So _. No limitations . " b. Ci at.ion 1 offw purposes( .- .cA . ... .-- 0..y be

  18. Savannah River Laboratory environmental transport and effects research. Annual report, 1978

    Energy Technology Data Exchange (ETDEWEB)

    Crawford, T.V. (comp.)

    1979-11-01

    Research in the environmental sciences by the Savannah River Laboratory during 1978 is described in 43 articles. These articles are in the fields of terrestrial ecology, geologic studies, aquatic transport, aquatic ecology, atmospheric transport, emergency response, computer methods development, ocean program, and fuel cycle program. Thirty-seven of the articles were abstracted individually for ERA/EDB; those in scope were also included in INIS.

  19. Laboratory Directed Research and Development Program. Annual report to the Department of Energy, December 1997

    Energy Technology Data Exchange (ETDEWEB)

    Ogeka, G.J.; Searing, J.M.

    1997-12-01

    New ideas and opportunities fostering the advancement of technology are occurring at an ever increasing rate. It, therefore, seems appropriate that a vehicle be available which fosters the development of new ideas and technologies, promotes the early exploration and exploitation of creative and innovative concepts, and develops new fundable R and D projects and programs if BNL is to carry out its primary mission and support the basic Department of Energy activities. At Brookhaven National Laboratory one such method is through its Laboratory Directed Research and Development Program. This discretionary research and development tool is critical in maintaining the scientific excellence and vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor in achieving and maintaining staff excellence and a means to address national needs within the overall mission of the DOE and BNL. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, they have resulted in numerous publications in various professional and scientific journals and presentations at meetings and forums.

  20. Laboratory Directed Research and Development Program annual report to the Department of Energy, December 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-01

    New ideas and opportunities fostering the advancement of technology are occurring at an ever increasing rate. It, therefore, seems appropriate that a vehicle be available which fosters the development of new ideas and technologies, promotes the early exploration and exploitation of creative and innovative concepts, and develops new fundable R and D projects and programs if BNL is to carry out its primary mission and support the basic Department of Energy activities. At Brookhaven National Laboratory one such method is through its Laboratory Directed Research and Development Program. This discretionary research and development tool is critical in maintaining the scientific excellence and vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor in achieving and maintaining staff excellence and a means to address national needs within the overall mission of the DOE and BNL. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, they have resulted in numerous publications in various professional and scientific journals and presentations at meetings and forums.

  1. LABORATORY DIRECTED RESEARCH AND DEVELOPMENT ANNUAL REPORT TO THE DEPARTMENT OF ENERGY - DECEMBER 2000.

    Energy Technology Data Exchange (ETDEWEB)

    FOX,K.J.

    2000-12-31

    The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and I exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, ,projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its Laboratory Directed Research and Development Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community, fostering new science and technology ideas, which is a major factor in achieving and maintaining staff excellence and a means to address national needs within the overall mission of the DOE and BNL. The LDRD Annual Report contains summaries of all research activities funded during Fiscal Year 2000. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, they have resulted in numerous publications in various professional and scientific journals and presentations at meetings and forums. All FY 2000 projects are listed and tabulated in the Project Funding Table. Also included in this Annual Report in Appendix A is a summary of the proposed projects for FY 2001. The BNL LDRD budget authority by DOE in FY 2000 was $6 million. The.actual allocation totaled $5.5 million. The following sections in this report contain the management processes, peer

  2. Pacific Northwest Laboratory annual report for 1994 to the DOE Office of Energy Research. Part 2: Atmospheric and climate research

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-01

    Atmospheric research at Pacific Northwest Laboratory (PNL) occurs in conjunction with the Atmospheric Chemistry Program (ACP) and with the Atmospheric Studies in Complex Terrain (ASCOT) Program. Solicitations for proposals and peer review were used to select research projects for funding in FY 1995. Nearly all ongoing projects were brought to a close in FY 1994. Therefore, the articles in this volume include a summary of the long-term accomplishments as well as the FY 1994 progress made on these projects. The following articles present summaries of the progress in FY 1994 under these research tasks: continental and oceanic fate of pollutants; research aircraft operations; ASCOT program management; coupling/decoupling of synoptic and valley circulations; interactions between surface exchange processes and atmospheric circulations; and direct simulations of atmospheric turbulence. Climate change research at PNL is aimed at reducing uncertainties in the fundamental processes that control climate systems that currently prevent accurate predictions of climate change and its effects. PNL is responsible for coordinating and integrating the field and laboratory measurement programs, modeling studies, and data analysis activities of the Atmospheric Radiation Measurements (ARM) program. In FY 1994, PNL scientists conducted 3 research projects under the ARM program. In the first project, the sensitivity of GCM grid-ad meteorological properties to subgrid-scale variations in surface fluxes and subgrid-scale circulation patterns is being tested in a single column model. In the second project, a new and computationally efficient scheme has been developed for parameterizing stratus cloud microphysics in general circulation models. In the last project, a balloon-borne instrument package is being developed for making research-quality measurements of radiative flux divergence profiles in the lowest 1,500 meters of the Earth`s atmosphere.

  3. A PACIFIC-WIDE GEOTHERMAL RESEARCH LABORATORY: THE PUNA GEOTHERMAL RESEARCH FACILITY

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, P.; Seki, A.; Chen, B.

    1985-01-22

    The Hawaii Geothermal Project (HGP-A) well, located in the Kilauea volcano east rift zone, was drilled to a depth of 6450 feet in 1976. It is considered to be one of the hot-test producing geothermal wells in the world. This single well provides 52,800 pounds per hour of 371 F and 160 pounds per square inch-absolute (psia) steam to a 3-megawatt power plant, while the separated brine is discharged in percolating ponds. About 50,000 pounds per hour of 368 F and 155 psia brine is discharged. Geothermal energy development has increased steadily in Hawaii since the completion of HGP-A in 1976: (1) a 3 megawatt power plant at HGP-A was completed and has been operating since 1981; (2) Hawaiian Electric Company (HECO) has requested that their next increment in power production be from geothermal steam; (3) three development consortia are actively, or in the process of, drilling geothermal exploration wells on the Big Island; and (4) engineering work on the development of a 400 megawatt undersea cable for energy transmission is continuing, with exploratory discussions being initiated on other alternatives such as hydrogen. The purpose for establishing the Puna Geothermal Research Facility (PGRF) is multifold. PGRF provides a facility in Puna for high technology research, development, and demonstration in geothermal and related activities; initiate an industrial park development; and examine multi-purpose dehydration and biomass applications related to geothermal energy utilization.

  4. Service Integration to Enhance Research Data Management: RSpace Electronic Laboratory Notebook Case Study

    Directory of Open Access Journals (Sweden)

    Stuart Macdonald

    2015-02-01

    Full Text Available Research Data Management (RDM provides a framework that supports researchers and their data throughout the course of their research and is increasingly regarded as one of the essential areas of responsible conduct of research. New tools and infrastructures make possible the generation of large volumes of digital research data in a myriad of formats. This facilitates new ways to analyse, share and reuse these outputs, with libraries, IT services and other service units within academic institutions working together with the research community to develop RDM infrastructures to curate and preserve this type of research output and make them re-usable for future generations. Working on the principle that a rationalised and continuous flow of data between systems and across institutional boundaries is one of the core goals of information management, this paper will highlight service integration via Electronic Laboratory Notebooks (ELN, which streamline research data workflows, result in efficiency gains for researchers, research administrators and other stakeholders, and ultimately enhance the RDM process.

  5. Research on fission induced plasmas and nuclear pumped lasers at the Los Alamos Scientific Laboratory

    Science.gov (United States)

    Helmick, H. H.

    1979-01-01

    A program of research on gaseous uranium and uranium plasmas is being conducted at The Los Alamos Scientific Laboratory under sponsorship of the National Aeronautics and Space Administration. The objective of this work is twofold: (1) to demonstrate the proof of principle of a gaseous uranium fueled reactor, and (2) pursue fundamental research on nuclear pumped lasers. The relevancy of the two parallel programs is embodied in the possibility of a high-performance uranium plasma reactor being used as the power supply for a nuclear pumped laser system. The accomplishments in the two above fields are summarized

  6. Establishment of Next-Generation Neurosurgery Research and Training Laboratory with Integrated Human Performance Monitoring.

    Science.gov (United States)

    Bernardo, Antonio

    2017-10-01

    Quality of neurosurgical care and patient outcomes are inextricably linked to surgical and technical proficiency and a thorough working knowledge of microsurgical anatomy. Neurosurgical laboratory-based cadaveric training is essential for the development and refinement of technical skills before their use on a living patient. Recent biotechnological advances including 3-dimensional (3D) microscopy and endoscopy, 3D printing, virtual reality, surgical simulation, surgical robotics, and advanced neuroimaging have proved to reduce the learning curve, improve conceptual understanding of complex anatomy, and enhance visuospatial skills in neurosurgical training. Until recently, few means have allowed surgeons to obtain integrated surgical and technological training in an operating room setting. We report on a new model, currently in use at our institution, for technologically integrated surgical training and innovation using a next-generation microneurosurgery skull base laboratory designed to recreate the setting of a working operating room. Each workstation is equipped with a 3D surgical microscope, 3D endoscope, surgical drills, operating table with a Mayfield head holder, and a complete set of microsurgical tools. The laboratory also houses a neuronavigation system, a surgical robotic, a surgical planning system, 3D visualization, virtual reality, and computerized simulation for training of surgical procedures and visuospatial skills. In addition, the laboratory is equipped with neurophysiological monitoring equipment in order to conduct research into human factors in surgery and the respective roles of workload and fatigue on surgeons' performance. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. West Texas array experiment: Noise and source characterization of short-range infrasound and acoustic signals, along with lab and field evaluation of Intermountain Laboratories infrasound microphones

    Science.gov (United States)

    Fisher, Aileen

    The term infrasound describes atmospheric sound waves with frequencies below 20 Hz, while acoustics are classified within the audible range of 20 Hz to 20 kHz. Infrasound and acoustic monitoring in the scientific community is hampered by low signal-to-noise ratios and a limited number of studies on regional and short-range noise and source characterization. The JASON Report (2005) suggests the infrasound community focus on more broad-frequency, observational studies within a tactical distance of 10 km. In keeping with that recommendation, this paper presents a study of regional and short-range atmospheric acoustic and infrasonic noise characterization, at a desert site in West Texas, covering a broad frequency range of 0.2 to 100 Hz. To spatially sample the band, a large number of infrasound gauges was needed. A laboratory instrument analysis is presented of the set of low-cost infrasound sensors used in this study, manufactured by Inter-Mountain Laboratories (IML). Analysis includes spectra, transfer functions and coherences to assess the stability and range of the gauges, and complements additional instrument testing by Sandia National Laboratories. The IMLs documented here have been found reliably coherent from 0.1 to 7 Hz without instrument correction. Corrections were built using corresponding time series from the commercially available and more expensive Chaparral infrasound gauge, so that the corrected IML outputs were able to closely mimic the Chaparral output. Arrays of gauges are needed for atmospheric sound signal processing. Our West Texas experiment consisted of a 1.5 km aperture, 23-gauge infrasound/acoustic array of IMLs, with a compact, 12 m diameter grid-array of rented IMLs at the center. To optimize signal recording, signal-to-noise ratio needs to be quantified with respect to both frequency band and coherence length. The higher-frequency grid array consisted of 25 microphones arranged in a five by five pattern with 3 meter spacing, without

  8. Chemistry {ampersand} Materials Science program report, Weapons Resarch and Development and Laboratory Directed Research and Development FY96

    Energy Technology Data Exchange (ETDEWEB)

    Chase, L.

    1997-03-01

    This report is the annual progress report for the Chemistry Materials Science Program: Weapons Research and Development and Laboratory Directed Research and Development. Twenty-one projects are described separately by their principal investigators.

  9. Discourse, Power, and Knowledge in the Management of "Big Science": The Production of Consensus in a Nuclear Fusion Research Laboratory.

    Science.gov (United States)

    Kinsella, William J.

    1999-01-01

    Extends a Foucauldian view of power/knowledge to the archetypical knowledge-intensive organization, the scientific research laboratory. Describes the discursive production of power/knowledge at the "big science" laboratory conducting nuclear fusion research and illuminates a critical incident in which the fusion research…

  10. Improving Validity of Informed Consent for Biomedical Research in Zambia Using a Laboratory Exposure Intervention

    Science.gov (United States)

    Zulu, Joseph Mumba; Lisulo, Mpala Mwanza; Besa, Ellen; Kaonga, Patrick; Chisenga, Caroline C.; Chomba, Mumba; Simuyandi, Michelo; Banda, Rosemary; Kelly, Paul

    2014-01-01

    Background Complex biomedical research can lead to disquiet in communities with limited exposure to scientific discussions, leading to rumours or to high drop-out rates. We set out to test an intervention designed to address apprehensions commonly encountered in a community where literacy is uncommon, and where complex biomedical research has been conducted for over a decade. We aimed to determine if it could improve the validity of consent. Methods Data were collected using focus group discussions, key informant interviews and observations. We designed an intervention that exposed participants to a detailed demonstration of laboratory processes. Each group was interviewed twice in a day, before and after exposure to the intervention in order to assess changes in their views. Results Factors that motivated people to participate in invasive biomedical research included a desire to stay healthy because of the screening during the recruitment process, regular advice from doctors, free medical services, and trust in the researchers. Inhibiting factors were limited knowledge about samples taken from their bodies during endoscopic procedures, the impact of endoscopy on the function of internal organs, and concerns about the use of biomedical samples. The belief that blood can be used for Satanic practices also created insecurities about drawing of blood samples. Further inhibiting factors included a fear of being labelled as HIV positive if known to consult heath workers repeatedly, and gender inequality. Concerns about the use and storage of blood and tissue samples were overcome by a laboratory exposure intervention. Conclusion Selecting a group of members from target community and engaging them in a laboratory exposure intervention could be a useful tool for enhancing specific aspects of consent for biomedical research. Further work is needed to determine the extent to which improved understanding permeates beyond the immediate group participating in the intervention

  11. Improving validity of informed consent for biomedical research in Zambia using a laboratory exposure intervention.

    Directory of Open Access Journals (Sweden)

    Joseph Mumba Zulu

    Full Text Available Complex biomedical research can lead to disquiet in communities with limited exposure to scientific discussions, leading to rumours or to high drop-out rates. We set out to test an intervention designed to address apprehensions commonly encountered in a community where literacy is uncommon, and where complex biomedical research has been conducted for over a decade. We aimed to determine if it could improve the validity of consent.Data were collected using focus group discussions, key informant interviews and observations. We designed an intervention that exposed participants to a detailed demonstration of laboratory processes. Each group was interviewed twice in a day, before and after exposure to the intervention in order to assess changes in their views.Factors that motivated people to participate in invasive biomedical research included a desire to stay healthy because of the screening during the recruitment process, regular advice from doctors, free medical services, and trust in the researchers. Inhibiting factors were limited knowledge about samples taken from their bodies during endoscopic procedures, the impact of endoscopy on the function of internal organs, and concerns about the use of biomedical samples. The belief that blood can be used for Satanic practices also created insecurities about drawing of blood samples. Further inhibiting factors included a fear of being labelled as HIV positive if known to consult heath workers repeatedly, and gender inequality. Concerns about the use and storage of blood and tissue samples were overcome by a laboratory exposure intervention.Selecting a group of members from target community and engaging them in a laboratory exposure intervention could be a useful tool for enhancing specific aspects of consent for biomedical research. Further work is needed to determine the extent to which improved understanding permeates beyond the immediate group participating in the intervention.

  12. Hydrologic transport of depleted uranium associated with open air dynamic range testing at Los Alamos National Laboratory, New Mexico, and Eglin Air Force Base, Florida

    Energy Technology Data Exchange (ETDEWEB)

    Becker, N.M. [Los Alamos National Lab., NM (United States); Vanta, E.B. [Wright Laboratory Armament Directorate, Eglin Air Force Base, FL (United States)

    1995-05-01

    Hydrologic investigations on depleted uranium fate and transport associated with dynamic testing activities were instituted in the 1980`s at Los Alamos National Laboratory and Eglin Air Force Base. At Los Alamos, extensive field watershed investigations of soil, sediment, and especially runoff water were conducted. Eglin conducted field investigations and runoff studies similar to those at Los Alamos at former and active test ranges. Laboratory experiments complemented the field investigations at both installations. Mass balance calculations were performed to quantify the mass of expended uranium which had transported away from firing sites. At Los Alamos, it is estimated that more than 90 percent of the uranium still remains in close proximity to firing sites, which has been corroborated by independent calculations. At Eglin, we estimate that 90 to 95 percent of the uranium remains at test ranges. These data demonstrate that uranium moves slowly via surface water, in both semi-arid (Los Alamos) and humid (Eglin) environments.

  13. Pacific Northwest Laboratory annual report for 1991 to the DOE Office of Energy Research

    Energy Technology Data Exchange (ETDEWEB)

    1992-05-01

    Within the US Department of Energy's (DOE's) Office of Health and Environmental Research (OHER), the atmospheric sciences and carbon dioxide research programs are part of the Environmental Sciences Division (ESD). One of the central missions of the division Is to provide the DOE with scientifically defensible information on the local, regional, and global distributions of energy-related pollutants and their effects on climate. This information is vital to the definition and Implementation of a sound national energy strategy. This volume reports on the progress and status of all OHER atmospheric science and climate research projects at the Pacific Northwest Laboratory (PNL). Research at PNL provides basic scientific underpinnings to DOE's program of global climate research. Research projects within the core carbon dioxide and ocean research programs are now integrated with those in the Atmospheric Radiation Measurements (ARM), the Computer Hardware, Advanced Mathematics and Model Physics (CHAMMP), and quantitative links programs to form DOEs contribution to the US Global Change Research Program. Climate research in the ESD has the common goal of improving our understanding of the physical, chemical, biological, and social processes that influence the Earth system so that national and international policymaking relating to natural and human-induced changes in the Earth system can be given a firm scientific basis. This report describes the progress In FY 1991 in each of these areas.

  14. Pacific Northwest Laboratory annual report for 1992 to the DOE Office of Energy Research

    Energy Technology Data Exchange (ETDEWEB)

    Grove, L.K. (ed.)

    1993-03-01

    The 1992 Annual Report from Pacific Northwest Laboratory (PNL) to the US Department of Energy (DOE) describes research in environment and health conducted during fiscal year 1992. This report consists of four volumes oriented to particular segments of the PNL program, describing research performed for the DOE Office of Health and Environmental Research in the Office of Energy Research. The parts of the 1992 Annual Report are: Biomedical Sciences; Environmental Sciences; Atmospheric Sciences; and Physical Sciences. This Report is Part II: Environmental Sciences. Included in this report are developments in Subsurface Science, Terrestrial Science, Laboratory-Directed Research and Development, Interactions with Educational Institutions, Technology Transfer, Publications, and Presentations. The research is directed toward developing a fundamental understanding of subsurface and terrestrial systems as a basis for both managing these critical resources and addressing environmental problems such as environmental restoration and global change. The Technology Transfer section of this report describes a number of examples in which fundamental research is laying the groundwork for the technology needed to resolve important environmental problems. The Interactions with Educational Institutions section of the report illustrates the results of a long-term, proactive program to make PNL facilities available for university and preuniversity education and to involve educational institutions in research programs. The areas under investigation include the effect of geochemical and physical phenomena on the diversity and function of microorganisms in deep subsurface environments, ways to address subsurface heterogeneity, and ways to determine the key biochemical and physiological pathways (and DNA markers) that control nutrient, water, and energy dynamics in arid ecosystems and the response of these systems to disturbance and climatic change.

  15. A survey on faculty perspectives on the transition to a biochemistry course-based undergraduate research experience laboratory.

    Science.gov (United States)

    Craig, Paul A

    2017-09-01

    It will always remain a goal of an undergraduate biochemistry laboratory course to engage students hands-on in a wide range of biochemistry laboratory experiences. In 2006, our research group initiated a project for in silico prediction of enzyme function based only on the 3D coordinates of the more than 3800 proteins "of unknown function" in the Protein Data Bank, many of which resulted from the Protein Structure Initiative. Students have used the ProMOL plugin to the PyMOL molecular graphics environment along with BLAST, Pfam, and Dali to predict protein functions. As young scientists, these undergraduate research students wanted to see if their predictions were correct and so they developed an approach for in vitro testing of predicted enzyme function that included literature exploration, selection of a suitable assay and the search for commercially available substrates. Over the past two years, a team of faculty members from seven different campuses (California Polytechnic San Luis Obispo, Hope College, Oral Roberts University, Rochester Institute of Technology, St. Mary's University, Ursinus College, and Purdue University) have transferred this approach to the undergraduate biochemistry teaching laboratory as a Course-based Undergraduate Research Experience. A series of ten course modules and eight instructional videos have been created (www.promol.org/home/basil-modules-1) and the group is now expanding these resources, creating assessments and evaluating how this approach helps student to grow as scientists. The focus of this manuscript will be the logistical implications of this transition on campuses that have different cultures, expectations, schedules, and student populations. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(5):426-436, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

  16. Modification of streaming potential by precipitation of calcite in a sand-water system: laboratory measurements pH range from 4 to 12

    OpenAIRE

    Guichet, Xavier; Jouniaux, Laurence; Catel, Nicole

    2006-01-01

    The definitive version is available at www.blackwell-synergy.com; We acknowledge the Geophysical Journal International, the Royal Astronomical Society and Blackwell Publishing. Full bibliographic reference is : Guichet, X., L. Jouniaux, and N. Catel, Modification of streaming potential by precipitation of calcite in a sand-water system: laboratory measurements in the pH range from 4 to 12, Geophysical Journal International, 166, 445-460, doi:10.1111/j.1365-246X.2006.02922.x, 2006; Spontaneous...

  17. Advanced Laboratory at Texas State University: Error Analysis, Experimental Design, and Research Experience for Undergraduates

    Science.gov (United States)

    Ventrice, Carl

    2009-04-01

    Physics is an experimental science. In other words, all physical laws are based on experimentally observable phenomena. Therefore, it is important that all physics students have an understanding of the limitations of certain experimental techniques and the associated errors associated with a particular measurement. The students in the Advanced Laboratory class at Texas State perform three detailed laboratory experiments during the semester and give an oral presentation at the end of the semester on a scientific topic of their choosing. The laboratory reports are written in the format of a ``Physical Review'' journal article. The experiments are chosen to give the students a detailed background in error analysis and experimental design. For instance, the first experiment performed in the spring 2009 semester is entitled Measurement of the local acceleration due to gravity in the RFM Technology and Physics Building. The goal of this experiment is to design and construct an instrument that is to be used to measure the local gravitational field in the Physics Building to an accuracy of ±0.005 m/s^2. In addition, at least one of the experiments chosen each semester involves the use of the research facilities within the physics department (e.g., microfabrication clean room, surface science lab, thin films lab, etc.), which gives the students experience working in a research environment.

  18. Promoting Science Outdoor Activities for Elementary School Children: Contributions from a research laboratory

    Science.gov (United States)

    Boaventura, Diana; Faria, Cláudia; Chagas, Isabel; Galvão, Cecília

    2013-03-01

    The purposes of the study were to analyse the promotion of scientific literacy through practical research activities and to identify children's conceptions about scientists and how they do science. Elementary school children were engaged in two scientific experiments in a marine biology research laboratory. A total of 136 students answered a questionnaire about their previous habits towards science and carried out the following actions: (1) a guided visit to the laboratory, (2) a brief presentation of the research theme, (3) the development of two experiments, and (4) a questionnaire about the experiments and science conceptions. The research methods included observation, document analysis, and content analysis of the answers to the questionnaires. Additionally, each visit was video recorded in order to design learning materials. The results revealed that most of the pupils were able to follow every stage of experimentation. However, some of them misinterpreted results and conclusions. One implication of the study is that this type of outdoor activity is extremely important to promote meaningful science learning in children, but more care should be taken in practical science activities so that children can overcome some common difficulties when performing scientific inquiry.

  19. A critical Action Research approach to curriculum development in a laboratory-based chemical engineering course

    Science.gov (United States)

    White, Scott R.

    This dissertation is a report of an attempt to critically evaluate a novel laboratory course from within the context of a chemical engineering curriculum. The research was done in a college classroom-laboratory setting, entrenched in the everydayness of classroom activities. All of the students, instructors, and educational researchers were knowing participants in this Action Research study. The students, a mixture of juniors, seniors, & graduate students, worked together on semester-long projects in groups that were mixed by age, gender and academic level. Qualitative techniques were used to gather different forms of representations of the students and instructors' experiences. Emergent patterns from the data gave strength to emergent knowledge claims that informed the instructors and the researcher about what the students were learning about performing experimental work and communicating results with their peers and instructor. The course challenged and in some cases changed the conceptions of instruction previously held by the students and the instructors. The course did not proceed without problems, yet the majority of these problems were overcome by the design of the course. Assertions and recommendations for improvement and application to other educational contexts are suggested.

  20. Pacific Northwest Laboratory annual report for 1991 to the DOE Office of Energy Research

    Energy Technology Data Exchange (ETDEWEB)

    Perez, D.A. (ed.)

    1992-02-01

    This report summarizes progress in environmental sciences research conducted by Pacific Northwest Laboratory (PNL) for the US Department of Energy's (DOE) Office of Health and Environmental Research in FY 1991. Each project in the PNL research program is a component in an integrated laboratory, intermediate-scale, and field approach designed to examine multiple phenomena at increasing levels of complexity. Examples include definition of the role of fundamental geochemical and physical phenomena on the diversity and function of microorganisms in the deep subsurface, and determination of the controls on nutrient, water, and energy dynamics in arid ecosystems and their response to stress at the landscape scale. The Environmental Science Research Center has enable PNL to extend fundamental knowledge of subsurface science to develop emerging new concepts for use in natural systems and in environmental restoration of DOE sites. New PNL investments have been made in developing advanced concepts for addressing chemical desorption kinetics, enzyme transformations and redesign, the role of heterogeneity in contaminant transport, and modeling of fundamental ecological processes.