QM/MM Calculations with deMon2k

Directory of Open Access Journals (Sweden)

Dennis R. Salahub

2015-03-01

Full Text Available The density functional code deMon2k employs a fitted density throughout (Auxiliary Density Functional Theory, which offers a great speed advantage without sacrificing necessary accuracy. Powerful Quantum Mechanical/Molecular Mechanical (QM/MM approaches are reviewed. Following an overview of the basic features of deMon2k that make it efficient while retaining accuracy, three QM/MM implementations are compared and contrasted. In the first, deMon2k is interfaced with the CHARMM MM code (CHARMM-deMon2k; in the second MM is coded directly within the deMon2k software; and in the third the Chemistry in Ruby (Cuby wrapper is used to drive the calculations. Cuby is also used in the context of constrained-DFT/MM calculations. Each of these implementations is described briefly; pros and cons are discussed and a few recent applications are described briefly. Applications include solvated ions and biomolecules, polyglutamine peptides important in polyQ neurodegenerative diseases, copper monooxygenases and ultra-rapid electron transfer in cryptochromes.

Differentiation and gene flow among European populations of Leishmania infantum MON-1.

Directory of Open Access Journals (Sweden)

Katrin Kuhls

2008-07-01

Full Text Available Leishmania infantum is the causative agent of visceral and cutaneous leishmaniasis in the Mediterranean region, South America, and China. MON-1 L. infantum is the predominating zymodeme in all endemic regions, both in humans and dogs, the reservoir host. In order to answer important epidemiological questions it is essential to discriminate strains of MON-1.We have used a set of 14 microsatellite markers to analyse 141 strains of L. infantum mainly from Spain, Portugal, and Greece of which 107 strains were typed by MLEE as MON-1. The highly variable microsatellites have the potential to discriminate MON-1 strains from other L. infantum zymodemes and even within MON-1 strains. Model- and distance-based analysis detected a considerable amount of structure within European L. infantum. Two major monophyletic groups-MON-1 and non-MON-1-could be distinguished, with non-MON-1 being more polymorphic. Strains of MON-98, 77, and 108 were always part of the MON-1 group. Among MON-1, three geographically determined and genetically differentiated populations could be identified: (1 Greece; (2 Spain islands-Majorca/Ibiza; (3 mainland Portugal/Spain. All four populations showed a predominantly clonal structure; however, there are indications of occasional recombination events and gene flow even between MON-1 and non-MON-1. Sand fly vectors seem to play an important role in sustaining genetic diversity. No correlation was observed between Leishmania genotypes, host specificity, and clinical manifestation. In the case of relapse/re-infection, only re-infections by a strain with a different MLMT profile can be unequivocally identified, since not all strains have individual MLMT profiles.In the present study for the first time several key epidemiological questions could be addressed for the MON-1 zymodeme, because of the high discriminatory power of microsatellite markers, thus creating a basis for further epidemiological investigations.

Differentiation and Gene Flow among European Populations of Leishmania infantum MON-1

Science.gov (United States)

Kuhls, Katrin; Chicharro, Carmen; Cañavate, Carmen; Cortes, Sofia; Campino, Lenea; Haralambous, Christos; Soteriadou, Ketty; Pratlong, Francine; Dedet, Jean-Pierre; Mauricio, Isabel; Miles, Michael; Schaar, Matthias; Ochsenreither, Sebastian; Radtke, Oliver A.; Schönian, Gabriele

2008-01-01

Background Leishmania infantum is the causative agent of visceral and cutaneous leishmaniasis in the Mediterranean region, South America, and China. MON-1 L. infantum is the predominating zymodeme in all endemic regions, both in humans and dogs, the reservoir host. In order to answer important epidemiological questions it is essential to discriminate strains of MON-1. Methodology/Principal Findings We have used a set of 14 microsatellite markers to analyse 141 strains of L. infantum mainly from Spain, Portugal, and Greece of which 107 strains were typed by MLEE as MON-1. The highly variable microsatellites have the potential to discriminate MON-1 strains from other L. infantum zymodemes and even within MON-1 strains. Model- and distance-based analysis detected a considerable amount of structure within European L. infantum. Two major monophyletic groups—MON-1 and non-MON-1—could be distinguished, with non-MON-1 being more polymorphic. Strains of MON-98, 77, and 108 were always part of the MON-1 group. Among MON-1, three geographically determined and genetically differentiated populations could be identified: (1) Greece; (2) Spain islands–Majorca/Ibiza; (3) mainland Portugal/Spain. All four populations showed a predominantly clonal structure; however, there are indications of occasional recombination events and gene flow even between MON-1 and non-MON-1. Sand fly vectors seem to play an important role in sustaining genetic diversity. No correlation was observed between Leishmania genotypes, host specificity, and clinical manifestation. In the case of relapse/re-infection, only re-infections by a strain with a different MLMT profile can be unequivocally identified, since not all strains have individual MLMT profiles. Conclusion In the present study for the first time several key epidemiological questions could be addressed for the MON-1 zymodeme, because of the high discriminatory power of microsatellite markers, thus creating a basis for further epidemiological

Film Presentation: Big Bang, mes ancêtres et moi

CERN Multimedia

2010-01-01

Big Bang, mes ancêtres et moi, by Franco-German TV producer ARTE (2009)   What do we know about the origins of the world today? This documentary presents a voyage into the mystery of these origins, accompanied by passionate scientists such as paleoanthropologist Pascal Picq, astrophysicist Hubert Reeves, physicist Etienne Klein and quantum gravity theorist Abhay Ashtekar. Organized around three key moments – the birth of the Universe, the appearance of life and the origins of mankind – this investigation takes us to various research areas around the world, including the large underground particle accelerator at CERN. The German version of this film, Big Bang im Labor, will be presented on 1st October. Big Bang, mes ancêtres et moi will be shown on Friday, 24 September from 13:00 to 14:00 in room 222-R-001 Language: French Big Bang im Labor will be shown on Friday, 1 October from 13:00 to 14:00 in the Main Auditorium Language : German   &nbs...

Initial mass function in R-associations CMaR1, Mon R1 and Mon R2 from radiodata

International Nuclear Information System (INIS)

Pyatunina, T.B.

1985-01-01

Results of search for compact radiosources in R-associations CMa R1 and Mon R1 carried out with the radiotelescope RATAN-600 at the 7.6-cm wavelength are given. The number of sources found in the association Mon R1 is approximately equal to the expected number of background extragalactic radiosources. In the association CMa R1 seven radiosources of small angular diameter with the flux greater than 30 mJy are found, two of which probably are background sources. A comparison of optical and radiodata on the association CMa R1 and previously published data on the association Mon R2 make it possible to estimate the initial mass function for associations under study: xi(M) infinity Msup(-2.7+-0.7) for stars with M approximately 10Msub(Sun)

Apskaitos politikos formavimo įmonėje tyrimai

OpenAIRE

Vaičiulytė-Petrauskienė, Edita

2009-01-01

Tyrimo objektas – apskaitos politikos formavimas įmonėje. Darbo tikslas – nustačius veiksnius, sąlygojančius apskaitos politikos pasirinkimą, sudaryti apskaitos politikos pasirinkimo pelno atžvilgiu modelį ir patikrinti jo tinkamumą Lietuvos įmonėse. Uždaviniai: 1) nustatyti pelną didinančios/mažinančios apskaitos politikos pasirinkimą sąlygojančius veiksnius; 2) išskirti ir nustatyti pelną didinančius ir pelną mažinančius apskaitos metodus, kuriuos pasirinkdamos įmonės formuoja savo apskaito...

What does Pokémon Go teach us about geography?

Directory of Open Access Journals (Sweden)

H. Gong

2017-06-01

Full Text Available Pokémon Go, a highly popular, recently launched augmented-reality-based video game, fosters players' interaction with the real world. In this commentary we elaborate on how location-based games, such as Pokémon Go, have provided insights into the perception and understanding of space, as well as into their impact on patterns of mobility. In addition to that, we compare Pokémon Go with geocaching, another location-based game, to further elaborate on what Pokémon Go fails to do in terms of the practices of geographical exploration.

Building Comprehensive and Sustainable Health Informatics Institutions in Developing Countries: Moi University Experience.

Science.gov (United States)

Were, Martin C; Siika, Abraham; Ayuo, Paul O; Atwoli, Lukoye; Esamai, Fabian

2015-01-01

Current approaches for capacity building in Health Informatics (HI) in developing countries mostly focus on training, and often rely on support from foreign entities. In this paper, we describe a comprehensive and multidimensional capacity-building framework by Lansang & Dennis, and its application for HI capacity building as implemented in a higher-education institution in Kenya. This framework incorporates training, learning-by-doing, partnerships, and centers of excellence. At Moi University (Kenya), the training dimensions include an accredited Masters in HI Program, PhD in HI, and HI short courses. Learning-by-doing occurs through work within MOH facilities at the AMPATH care and treatment program serving 3 million people. Moi University has formed strategic HI partnerships with Regenstrief Institute, Inc. (USA), University of Bergen (Norway), and Makerere University (Uganda), among others. The University has also created an Institute of Biomedical Informatics to serve as an HI Center of Excellence in the region. This Institute has divisions in Training, Research, Service and Administration. The HI capacity-building approach by Moi provides a model for adoption by other institutions in resource-limited settings.

L'etat, C'est Moi: Why provincial Intra-governmental disputes in ...

African Journals Online (AJOL)

L'etat, C'est Moi: Why provincial Intra-governmental disputes in Shout Africa remain ungoverned by the final constitution and the Intergovernmental Relations Framework Act - and how we can best resolve them.

[Contamination with genetically modified maize MON863 of processed foods on the market].

Science.gov (United States)

Ohgiya, Yoko; Sakai, Masaaki; Miyashita, Taeko; Yano, Koichi

2009-06-01

Genetically modified maize MON863 (MON863), which has passed a safety examination in Japan, is commercially cultivated in the United States as a food and a resource for fuel. Maize is an anemophilous flower, which easily hybridizes. However, an official method for quantifying the content of MON863 has not been provided yet in Japan. We here examined MON863 contamination in maize-processed foods that had no labeling indicating of the use of genetically modified maize.From March 2006 to July 2008, we purchased 20 frozen maize products, 8 maize powder products, 7 canned maize products and 4 other maize processed foods. Three primer pairs named MON 863 primer, MON863-1, and M3/M4 for MON863-specific integrated cassette were used for qualitative polymerase chain reaction (PCR). A primer pair "SSIIb-3" for starch synthase gene was used to confirm the quality of extracted DNA. The starch synthase gene was detected in all samples. In qualitative tests, the MON863-specific fragments were detected in 7 (18%) maize powder products out of the 39 processed foods with all the three primer pairs.We concluded that various maize processed foods on the market were contaminated with MON863. It is important to accumulate further information on MON863 contamination in maize-processed foods that have no label indication of the use of genetically modified maize.

Radio evidence for the initial stellar mass function in the R associations CMa R1, Mon R1, Mon R2

International Nuclear Information System (INIS)

Pyatunina, T.B.

1985-01-01

The R associations CMa R1 and Mon R1 have been searched for compact 7.6-cm sources with the RATAN-600 radio telescope. The Mon R1 region shows only about the expected number of background radio galaxies; in CMa R1 seven sources of small angular size with S> or =30 mJy have been found, two of them probably background objects. Comparison with optical data for CMa R1, together with previous RATAN-600 data for Mon R2, yields an initial mass function xi(M)proportionalM/sup -2.7plus-or-minus0.7/ for the rather massive (Mroughly-equal10 M/sub sun/) stars in these associations

ARC Code TI: NodeMon

Data.gov (United States)

National Aeronautics and Space Administration — NodeMon is a resource utilization monitor tailored to the Altix architecture, but is applicable to any Linux system or cluster. It allows distributed resource...

What does Pokémon Go teach us about geography?

OpenAIRE

H. Gong; R. Hassink; G. Maus

2017-01-01

Pokémon Go, a highly popular, recently launched augmented-reality-based video game, fosters players' interaction with the real world. In this commentary we elaborate on how location-based games, such as Pokémon Go, have provided insights into the perception and understanding of space, as well as into their impact on patterns of mobility. In addition to that, we compare Pokémon Go with geocaching, another location-based game, to further elaborate on what Pokémon Go fails to do i...

Management of Patients with Post- Traumatic Exposed Bones at Moi ...

African Journals Online (AJOL)

Background: The global frequency for open long bone fracture is at least 11.5 cases per 100,000 persons per year. Precise published research information regarding the characteristics and the management of patients with post- traumatic exposed bones for Africa, Kenya and Moi Teaching and Referral Hospital- Eldoret is ...

Kernel compositions of glyphosate-tolerant and corn rootworm-protected MON 88017 sweet corn and insect-protected MON 89034 sweet corn are equivalent to that of conventional sweet corn (Zea mays).

Science.gov (United States)

Curran, Kassie L; Festa, Adam R; Goddard, Scott D; Harrigan, George G; Taylor, Mary L

2015-03-25

Monsanto Co. has developed two sweet corn hybrids, MON 88017 and MON 89034, that contain biotechnology-derived (biotech) traits designed to enhance sustainability and improve agronomic practices. MON 88017 confers benefits of glyphosate tolerance and protection against corn rootworm. MON 89034 provides protection against European corn borer and other lepidopteran insect pests. The purpose of this assessment was to compare the kernel compositions of MON 88017 and MON 89034 sweet corn with that of a conventional control that has a genetic background similar to the biotech sweet corn but does not express the biotechnology-derived traits. The sweet corn samples were grown at five replicated sites in the United States during the 2010 growing season and the conventional hybrid and 17 reference hybrids were grown concurrently to provide an estimate of natural variability for all assessed components. The compositional analysis included proximates, fibers, amino acids, sugars, vitamins, minerals, and selected metabolites. Results highlighted that MON 88017 and MON 89034 sweet corns were compositionally equivalent to the conventional control and that levels of the components essential to the desired properties of sweet corn, such as sugars and vitamins, were more affected by growing environment than the biotech traits. In summary, the benefits of biotech traits can be incorporated into sweet corn with no adverse effects on nutritional quality.

15 Sawadogo_F 03.pmd

African Journals Online (AJOL)

hond

2 juil. 2007 ... moi » et « le non-moi », c'est-à-dire l'Autre, dans un contexte de communication des cultures (dans ..... radio, c'est Waogdo qui s'allume et je crois entendre les nouvelles de Manéga » (54); «. Mon cœur .... frère, courant, lance cette phrase à la terre des Aïeux : le Sud souhaite faire ta connais- sance » (8); ...

Metallic MoN layer and its application as anode for lithium-ion batteries

Science.gov (United States)

Zhang, Qiaoxuan; Ma, Jiachen; Lei, Ming; Quhe, Ruge

2018-04-01

Recently, two-dimensional (2D) metallic MoN was manufactured successfully in experiment. Its intrinsic properties remain to be explored theoretically, in depth. The intrinsic properties of a MoN monolayer are investigated by first-principles calculations. The distinct geometric properties of the outermost Mo and N surfaces are discovered. We predict an extremely high work function of 6.3 eV of the N surface, which indicates the great value of the 2D MoN for application in the semiconductor industry. We further explore the potential of 2D MoN as anode material for lithium-ion batteries. It is found that the adsorption energy of a single Li atom on an MoN surface can be as low as -4.04 eV. The small diffusion barriers (0.41 eV) and high theoretical maximum capacity (406 mAh · g-1 with the inclusion of multilayer adsorption) all imply an outstanding lithium-ion battery performance by 2D MoN.

Rancang Bangun Ulang Aplikasi MonTA Menggunakan Workflow Framework pada ASP.NET

Directory of Open Access Journals (Sweden)

Mohammad Oktri Radity

2013-09-01

Full Text Available Zaman sekarang kemajuan teknologi semakin berkembang pesat dari tahun ke tahun. Kebutuhan orang terhadap teknologi menjadi sangat penting. Aplikasi MonTA yang digunakan oleh jurusan Teknik Informatika ITS menjadi bukti kemajuan teknologi. Aplikasi yang dikembangkan oleh jurusan Teknik Informatika ini bertujuan untuk mengelola seluruh data tugas akhir mahasiswa Teknik Informatika. Aplikasi MonTA merupakan suatu sistem yang berkaitan dengan tugas akhir mahasiswa di jurusan Teknik Informatika, Institut Teknologi Sepuluh Nopember Surabaya. Tujuan dikembangkannya aplikasi ini adalah untuk mengelola data mahasiswa yang melaksanakan tugas akhir dan dosen dapat memonitoring mahasiswa yang sedang melakukan tugas akhir dengan aplikasi ini. Aplikasi ini juga memudahkan admin tugas akhir dalam melakukan tugasnya, antara lain: penjadwalan proposal, memonitor jumlah bimbingan mahasiswa tugas akhir, penjadwalan sidang tugas akhir, dan lain-lain. Namun, aplikasi MonTA yang sekarang digunakan masih memiliki banyak kekurangan. Oleh karena itu dibahas perancangan ulang aplikasi MonTA pada artikel ini. Metode baru yang digunakan pada rancang ulang aplikasi MonTA ini adalah dengan penerapan Workflow Framework pada ASP.NET. Diharapkan dengan rancang ulang aplikasi ini nantinya dapat memperbaiki berbagai kekurangan yang ada saat ini, seperti inkonsitensi data dan memperbaiki data yang terdapat pada  aplikasi MonTA menjadi lebih terstruktur

The electronic and optical properties of CH3NH3MoI3 perovskite

Science.gov (United States)

Kansara, Shivam; Sonvane, Yogesh; Gupta, Sanjeev K.

2018-05-01

In this work, a first-principles theoretical study of hybrid perovskite CH3NH3MoI3 is performed using PBE exchange-correlation approximations in density functional theory. The results of electronic band structure are 0.90 eV (M-point: Direct) and 0.60 eV (R-X point: Indirect), respectively. We have also calculated the dielectric properties such as real, imaginary, extension coefficient (K) and reflectivity (R) properties of hybrid perovskite CH3NH3MoI3. The low-bandgap molecules are used to absorb near-IR range and typically having a bandgap smaller than 1.6 eV. This is particularly attractive in organic photovoltaics (OPV), photodetectors (PDs), and ambipolar field-effect transistors (FETs).

Jean Frémon/Rue du Regard

OpenAIRE

Mokhtari, Sylvie

2012-01-01

La prose de Jean Frémon sur la peinture se déploie ici en 48 courts textes, dont une bonne moitié d’entre eux avait déjà connu une première édition dans des revues. Abordés isolément, les œuvres de Bill Viola, David Hockney, Antoni Tàpies, Gilles Aillaud, Roy Lichtenstein… sont soumises à la traduction littéraire qu’en donne le « regardeur de tableau, jardinier, journalier, vagabond » et écrivain. J. Frémon chemine entre art et littérature à la rencontre d’artistes qui l’interpellent dans l’H...

Pokémon Battles as a Context for Mathematical Modeling

Science.gov (United States)

McGuffey, William

2017-01-01

In this article I explore some of the underlying mathematics of Poke´mon battles and describe ways that teachers at the secondary level could explore concepts of mathematical game theory in this context. I discuss various ways of representing and analyzing a Poke´mon battle using game theory and conclude with an example of applying concepts of…

Pokémon Go: benefits, costs, and lessons for the conservation movement

OpenAIRE

Dorward, L; Mittermeier, JC; Sandbrook, C; Spooner, F

2016-01-01

Pokémon Go, an augmented reality (AR) smartphone game, replicates many aspects of real-world wildlife watching and natural history by allowing players to find, capture, and collect Pokémon, which are effectively virtual animals. In this paper, we consider how the unprecedented success of Pokémon Go as a smartphone game might create opportunities and challenges for the conservation movement. By encouraging players to go outside and consider various aspects of virtual species’ biology, the game...

SNS ønsker kommentarer om der er oplysninger der ændrer konklusionerne i risikovurderingen. Zea mays (MON863 X MON810). Brev fra Greenpeace til Nationale CAer

DEFF Research Database (Denmark)

Kjellsson, Gøsta; Damgaard, Christian; Strandberg, Morten Tune

2005-01-01

"DMU har ikke fundet nogen nye oplysninger i Greenpeace kommentarer til MON863 x MON810 majsen, der ændrer vores tidligere risikovurdering (konklusioner refereret i rammenotatet pr. 29.08.2005) for anvendelse til import og videreforarbejdning uden dyrkning. Vi har tidligere kommenteret Greenpeace...

La « faillite » du ciblage monétaire en Tunisie ?

Directory of Open Access Journals (Sweden)

Rima Lajnaf

2014-09-01

Full Text Available Les monétaristes ont montré que l’accélération de la masse monétaire ne ferait qu’attiser l’inflation. Leur idée a gagné en influence auprès des banques centrales, les incitant dans les années soixante-dix à s’efforcer de mieux maîtriser l’inflation en utilisant les agrégats monétaires comme les variables de leurs objectifs intermédiaires. Cependant, même si l’utilisation des cibles monétaires est répandue dans le monde entier, il n’existe pas de consensus sur la causalité entre la monnaie et les prix. Ce problème a fait l’objet d’un débat très animé entre les économistes surtout durant les trois dernières décennies caractérisées par l’innovation financière. La stratégie de ciblage de l’agrégat monétaire n’est efficace que si ce dernier, considéré comme une cible intermédiaire, possède des propriétés satisfaisantes en termes de stabilité, de contrôlabilité et du contenu en information. Dans ce papier, nous allons étudier l’efficacité de la politique d’ancrage monétaire en Tunisie en analysant les propriétés de l’agrégat M3. Les résultats montrent que le choix de cet agrégat comme un objectif intermédiaire ne semble pas être justifié.

V900 MON AND THOMMES' NEBULA: A NEW FUor IN MONOCEROS

Energy Technology Data Exchange (ETDEWEB)

Reipurth, Bo; Aspin, Colin [Institute for Astronomy, University of Hawaii at Manoa, 640 N. Aohoku Place, Hilo, HI 96720 (United States); Herbig, G. H., E-mail: herbig@ifa.hawaii.edu [Institute for Astronomy, University of Hawaii at Manoa, 2680 Woodlawn Drive, Honolulu, HI 96822 (United States)

2012-03-20

Detailed observations of a recently recognized eruptive variable, V900 Mon, are presented. The star is located in the small cloud L1656, a little-studied region of modest star formation activity in Monoceros, and is presently at a magnitude of r {approx} 16, surrounded by a bright compact reflection nebula, where only a 20th magnitude star was seen on the red first-epoch POSS plate. Optical spectra show a red absorption-line spectrum not later than mid-K, and the H{alpha} line and the Na I D{sub 12} doublet display prominent P Cygni profiles with massive absorption troughs indicating a cool outflowing wind. Near-infrared spectra show deep CO bandhead absorption and pronounced molecular bands of water vapor indicative of a much cooler object. This spectral appearance is very similar to that of FU Orionis, except that V900 Mon has a much higher reddening of A{sub V} {approx} 13 mag. The energy distribution of V900 Mon, compiled from non-simultaneous observations and thus dependent on possible luminosity changes, shows that V900 Mon is a Class I protostar with a massive cool envelope. At a distance of about 1100 pc, V900 Mon has a luminosity of 106 L{sub Sun} in the range of 0.55-160 {mu}m. These data identify V900 Mon as a new member of the rare class of FU Orionis variables.

Pokémon is Evolving! An investigation into the development of the Pokémon community and expectations for the future of the franchise

Directory of Open Access Journals (Sweden)

Carina Assunção

2017-06-01

Full Text Available Pokémon is one of Nintendo’s largest, most influential franchises. With a history ranging more than twenty years, its enormous fan-base spans video and trading card games, anime TV shows and films, amongst other media. This paper aims to investigate the Pokémon fan community while exploring how the franchise has grown: from its beginnings as a pop-culture phenomenon, to one of the strongest and friendliest gaming fan communities in existence today. Data gathered from 165 online respondents examines how fans’ past experiences with the franchise inform their expectations towards future products. It also explores how considerable efforts from developers – as well as the gaming community – contribute to the creative growth of a continually-expanding fan-base. Additionally, this study was in a unique position to gather data before two new Pokémon games were released: Pokken Tournament and Pokémon GO. The former did not generate high expectations but still performed well in terms of sales. The latter was thought of as a casual game but, as the world now knows, was a tremendous success. Insights obtained from researching fan attitudes to unreleased games show that expectations do not always become reality.

Familiarity increases the number of remembered Pokémon in visual short-term memory.

Science.gov (United States)

Xie, Weizhen; Zhang, Weiwei

2017-05-01

Long-term memory (LTM) can influence many aspects of short-term memory (STM), including increased STM span. However, it is unclear whether LTM enhances the quantitative or qualitative aspect of STM. That is, do we retain a larger number of representations or more precise representations in STM for familiar stimuli than unfamiliar stimuli? This study took advantage of participants' prior rich multimedia experience with Pokémon, without investing on laboratory training to examine how prior LTM influenced visual STM. In a Pokémon visual STM change detection task, participants remembered more first-generation Pokémon characters that they were more familiar with than recent-generation Pokémon characters that they were less familiar with. No significant difference in memory quality was found when quantitative and qualitative effects of LTM were isolated using receiver operating characteristic (ROC) analyses. Critically, these effects were absent in participants who were unfamiliar with first-generation Pokémon. Furthermore, several alternative interpretations were ruled out, including general video-gaming experience, subjective Pokémon preference, and verbal encoding. Together, these results demonstrated a strong link between prior stimulus familiarity in LTM and visual STM storage capacity.

On the Determinants and Outcomes of Passion for Playing Pokémon Go.

Science.gov (United States)

Orosz, Gábor; Zsila, Ágnes; Vallerand, Robert J; Böthe, Beáta

2018-01-01

In 2016, Pokémon Go became the most popular smartphone game. Despite the increasing popularity of this augmented reality game, to date, no studies have investigated passion for playing Pokémon Go. On the theoretical basis of the Dualistic Model of Passion (DMP), our goal was to investigate the associations between Pokémon Go playing motives, passion, and impulsivity. A total of 621 Pokémon Go players participated in the study (54.9% female; M age = 22.6 years, SD age = 4.4). It was found that impulsivity was more strongly associated with obsessive passion (OP) than with harmonious passion (HP). HP was associated with adaptive motives (i.e., outdoor activity, social, recreation, and nostalgia), while OP was associated with less adaptive motives (i.e., fantasy, escape, boredom, competition, and coping). Therefore, in line with the DMP, HP and OP for playing Pokémon Go can predict an almost perfectly distinguished set of adaptive or maladaptive playing motives, and OP has a noteworthy relationship with impulsivity as a determinant.

On the Determinants and Outcomes of Passion for Playing Pokémon Go

Science.gov (United States)

Orosz, Gábor; Zsila, Ágnes; Vallerand, Robert J.; Böthe, Beáta

2018-01-01

In 2016, Pokémon Go became the most popular smartphone game. Despite the increasing popularity of this augmented reality game, to date, no studies have investigated passion for playing Pokémon Go. On the theoretical basis of the Dualistic Model of Passion (DMP), our goal was to investigate the associations between Pokémon Go playing motives, passion, and impulsivity. A total of 621 Pokémon Go players participated in the study (54.9% female; Mage = 22.6 years, SDage = 4.4). It was found that impulsivity was more strongly associated with obsessive passion (OP) than with harmonious passion (HP). HP was associated with adaptive motives (i.e., outdoor activity, social, recreation, and nostalgia), while OP was associated with less adaptive motives (i.e., fantasy, escape, boredom, competition, and coping). Therefore, in line with the DMP, HP and OP for playing Pokémon Go can predict an almost perfectly distinguished set of adaptive or maladaptive playing motives, and OP has a noteworthy relationship with impulsivity as a determinant. PMID:29599735

Self Test of FlowMon Probe

OpenAIRE

Kříž, Blažej

2009-01-01

Cílem této práce je navrhnout a implementovat autotest sondy FlowMon, monitorující síťový provoz na základě IP toků, která byla vyvinuta během projektu Liberouter. Práce se věnuje teorii testování a kategoriím testů, které nejvíce souvisejí s vyvíjeným autotestem. Zde se také nachází stručný popis monitorování sítí pomocí NetFlow protokolu, spolu s popisem architektury sondy FlowMon. Práce dále obsahuje samotný návrh a řešení autotestu. Součástí řešení jsou dva programové celky. První předsta...

monIT: A Portuguese Risk Communication Project on EMF

International Nuclear Information System (INIS)

Oliveira, Carla; Sebastiao, Daniel; Carpinteiro, Goncalo; Fernandes, Carlos A.; Correia, Luis M.

2006-01-01

The monIT project is a risk communication programme, aiming at providing information on exposure to electromagnetic fields (EMF) from mobile communication systems in Portugal. monIT's website, www.lxlit.pt/monit, is the main interface for dissemination of information. Besides including relevant information about EMF for both the general public and the technical community, this website provides results from extensive measurement campaigns performed all over Portugal during the last three years. This paper presents the project's structure and activities, practical results achieved and ends with some conclusions and action lines for future work. (author)

Pokémon Go: An Unexpected Inspiration for Next Generation Learning Environments

Science.gov (United States)

Nigaglioni, Irene

2017-01-01

Although mobile applications and games often seem isolating and somewhat stationary, last year's augmented reality (AR) gaming craze Pokémon Go demonstrated how technology has the potential to promote socialization, collaboration, and physical activity while still engaging users. Pokémon Go's use of AR technology, which superimposes…

Bistand til risikovurdering (evt. ændringer af tidligere risikovurdering). Zea mays (MON863; MON863x810). Supplerende materiale til ansøgningen. Modtaget 07-09-2004, deadline 19-09-2004, svar 17-09-2004

DEFF Research Database (Denmark)

Kjellsson, Gøsta; Strandberg, Morten Tune

2012-01-01

"DMU har modtaget og vurderet de supplerende oplysninger (mail fra Skov- og Naturstyrelsen d. 07-09-2004) til ansøgningen om tilladelse til markedsføring af genetisk modificeret majs C/DE/02/09 (MON863 og MON863 x MON810). Vi har gennemgået oplysningerne i det tilsendte materiale for at se om de ...

Biudžetų naudojimas įmonės rizikos valdymo procese

OpenAIRE

Klimaitienė, Rūta; Kanapickienė, Rasa

2009-01-01

Kiekviena įmonė, pradėdama kurti biudžetų sistemą, viliasi, kad racionaliai sukurta biudžetų sistema joms leis kryptingai planuoti veiklą, ją koordinuoti ir kontroliuoti tam, kad būtų galima efektyviai naudoti materialinius ir kitus išteklius, kurie padėtų optimizuoti įmonės išlaidas ir maksimizuoti iš jų gaunamą naudą. Vienas eskaluojamų pagrindinių biudžetų tikslų – informacijos suformavimas, kurio pagrindu įmonės vadovai ir vadybininkai galėtų priimti sprendimus. Reikia paminėti, kad dažna...

Capturo Pokémons, “Logo Existo” - Realidade Aumentada e Consumo à Luz das Experiências dos Usuários do Pokémon Go

Directory of Open Access Journals (Sweden)

Breno de Paula Andrade Cruz

2017-09-01

Full Text Available Este estudo exploratório analisa o comportamento dos usuários brasileiros do aplicativo Pokémon GO no Twitter ao tornarem públicas suas experiências relativas ao jogo, bem como suas experiências de consumo ao capturarem Pokémons. A coleta de dados ocorreu em duas fases. Na primeira fase usou-se a ferramenta online Netlytic para monitorar o hashtag #PokemonGo no Twitter, tendo mais de 262 mil posts no mundo - o que evidenciou a necessidade de um recorte para o contexto brasileiro através de hashtags relacionados ao Brasil (532 posts. Na segunda fase trabalhou-se com a Netnografia em uma comunidade de fãs do jogo (Pokémon GO RJ. Os resultados destacam que: (i foram identificadas sete categorias relacionadas à experiência do usuário a partir dos dados do Twitter; (ii paras os fãs do jogo, a captura de Pokémons muitas vezes está associada ao consumo de alimentos e bebidas - o que demonstra que a experiência é mais ampla do que apenas usar o aplicativo; (iii jogadores(as formam grupos para capturarem personagens e consomem juntos; (iv os fãs do jogo entendem que empresas (principalmente de alimentos e bebidas usam a Poke Shop como estratégia para atrair clientes; e (v parece haver um dinamização do comércio (formal e informal nas regiões onde existem Pokémons. A apresentação da ferramenta Netlytic neste estudo apresenta implicações gerenciais, bem como possível impacto nos estudos em Marketing relacionados ao monitoramento de redes sociais virtuais, justificando assim a relevância deste estudo.

Monólogos: nuestra pequeña esencia

Directory of Open Access Journals (Sweden)

Maria del Carmen Chenoll Monzó

2010-01-01

Full Text Available La siguiente experiencia práctica trata, como bien dice el título, sobre los monólogos de humor que tan de moda se han puesto últimamente.Muchas veces, cuando nos encontramos ante una clase de extranjeros que quieren estudiar español, se nos plantea el dilema de cómo separar las clases de cultura con las de gramática. ¿Y por qué separarlas? Los monólogos nos permiten combinar varios aspectos, como mostrarles a los alumnos nuestra cultura más de cerca y que ellos nos muestren y comenten la suya (fomentamos de esta manera una conversación espontánea en clase y de la que todos, hasta los más tímidos, suelen participar.Además, obviamente, existe un claro segundo sentido e ironía a la que poco a poco se acostumbran (y que es uno de los aspectos más difíciles para tratar con los alumnos de E/LE y por supuesto, con una acertada elección del monólogo, también podemos clarificar y profundizar en ciertos aspectos gramaticales que nos interesen.

Geologic Mapping Investigations of Alba Mons, Mars

Science.gov (United States)

Crown, D. A.; Berman, D. C.; Scheidt, S. P.; Hauber, E.

2018-06-01

Geologic mapping of the summit region and western flank of Alba Mons at 1:1M-scale is revealing sequences of volcanic, tectonic, impact, and degradation processes that have formed and modified the northernmost of the Tharsis volcanoes.

Reanalysis of the radii of the Benchmark eclipsing binary V578 Mon

International Nuclear Information System (INIS)

Garcia, E. V.; Stassun, Keivan G.; Torres, Guillermo

2013-01-01

V578 Mon is an eclipsing binary system in which both stars have masses above 10 M ☉ determined with an accuracy better than 3%. It is one of only five such massive eclipsing binaries known that also possess eccentric orbits and measured apsidal motions, thus making it an important benchmark for theoretical stellar evolution models. However, recently reported determinations of the radii of V578 Mon differ significantly from previously reported values. We reanalyze the published data for V578 Mon and trace the discrepancy to the use of an incorrect formulation for the stellar potentials in the most recent analysis. Here we report corrected radii for this important benchmark eclipsing binary.

Pokémon Go: digital health interventions to reduce cardiovascular risk.

Science.gov (United States)

Krittanawong, Chayakrit; Aydar, Mehmet; Kitai, Takeshi

2017-10-01

Physical activity is associated with a lower risk of coronary heart disease/cardiovascular disease mortality, and current guidelines recommend physical activity for primary prevention in healthy individuals and secondary prevention in patients with coronary heart disease/cardiovascular disease. Over the last decade, playing classic video games has become one of the most popular leisure activities in the world, but is associated with a sedentary lifestyle. In the new era of rapidly evolving augmented reality technology, Pokémon Go, a well-known augmented reality game, may promote physical activity and prevent cardiovascular disease risks - that is, diabetes, obesity, and hypertension. Pokémon Go makes players willing to be physically active for regular and long periods of time. We report on an assessment of regular walking and playing Pokémon Go by performing data mining in Twitter.

Scientific Opinion of the Panel on Genetically Modified Organisms on an application (Reference EFSA-GMO-CZ-2006-33) for the placing on the market of the insect-resistant and glyphosate-tolerant genetically modified maize MON 88017 x MON 810, for food and feed uses, import and processing under

DEFF Research Database (Denmark)

Sørensen, Ilona Kryspin

. Further information from applications for placing the single insert lines MON 88017 and MON 810 on the market under EU regulatory procedures was taken into account where appropriate. The scope of application EFSA-GMO-CZ-2006-33 is for food and feed uses, import and processing of genetically modified maize...... MON 88017 x MON 810 and all derived products, but excluding cultivation in the EU. The EFSA GMO Panel assessed maize MON 88017 x MON 810 with reference to the intended uses and the appropriate principles described in the Guidance Document of the Scientific Panel on Genetically Modified Organisms...... or survival of feral maize plants in case of accidental release into the environment of maize MON 88017 x MON 810 viable grains during transportation and processing. The scope of the post-market environmental monitoring plan provided by the applicant is in line with the intended uses of maize MON 88017 x MON...

« Cognitus & Moi » : a computer-based cognitive remediation program for children with intellectual disability

Directory of Open Access Journals (Sweden)

Caroline eDemily

2016-02-01

Full Text Available Attentional, visuospatial and social cognition deficits have a negative impact on children’s adaptative and social competences and, as a result, on their ability to achieve a normal functioning and behavior. Until now and despite the frequency of those deficits, there is a lack of children’s specific cognitive remediation tools specifically dedicated to attentional and visuospatial areas.The « Cognitus & Moi » program involves a variety of exercises in a paper and/or pencil (n=30 or a computerized format (n=29 and a strategy coaching approach. Each module of « Cognitus & Moi » targets a single impaired cognitive area, within the limits of cognitive domains' overlapping. The little cartoon character named Cognitus, who illustrates the program, is supposed to be very friendly and kind towards children. Cognitus will accompany them throughout the program for an effective and positive reinforcement. The main goal of « Cognitus & Moi » is to adjust to children’s difficulties in daily life. Moreover, since the cognitive remediation benefit is complex to apply in daily life, the program is based on a metacognitive strategy. After a complete neuropsychological assessment and a psychoeducational session (with the child and the parents, 16 one hour-sessions of cognitive remediation with the therapist are proposed. Each session is composed of three parts: (1 computerized tasks focusing on specific attentional or visuo-spatial components (20 minutes. The attentional module targets hearing, visual and divided attention. A double attention task is also proposed. The visuo-spatial module targets eye tracking and gaze direction, spatial orientation, visuo-spatial memory and construction, and mental imagery.(2 pen and paper tasks focusing on the same processes (20 minutes and a facial emotion recognition task.(3 a proposal of a home-based task (during 20 minutes. Weekly, specific attentional and visuo-spatial home tasks are proposed to the child and

Les logiques spatiales monégasques

Directory of Open Access Journals (Sweden)

Jean-Christophe GAY

1996-06-01

Full Text Available La prospérité de la Principauté de Monaco s'explique par la valorisation ou la création de plusieurs abris emboîtés (climatique, fiscal, urbanistique se cumulant. De part et d'autre du «Rocher», triplement abrité, le territoire monégasque s'organise suivant deux axes conceptuels opposés.

Healthcare Encounters for Pokémon Go: Risks and Benefits of Playing.

Science.gov (United States)

Barbero, Erika M; Carpenter, Diane M; Maier, Joetta; Tseng, Daniel S

2018-04-30

Our aim was to quantify the health risks and benefits of Pokémon Go, an augmented reality game played on the mobile phone utilizing real-world locations. Healthcare encounters containing references to Pokémon Go in Kaiser Permanente Northern California (KPNC) from July 5, 2016 to November 5, 2016 were reviewed. Subjects were classified according to the nature of the healthcare encounter subsequent to playing Pokémon Go: adverse event/injury, self-reported benefit, or incidental mention. Comparisons were made using the Wilcoxon-Mann-Whitney nonparametric test where variables were continuous and the chi-squared or Fisher's exact test where variables were binomial. Of 222 Pokémon Go players reporting an adverse event or benefit, 75 (33.8%) experienced adverse events and 147 (66.2%) reported benefits. Among our cohort, 114 subjects (54.0%) were obese, and 62 (27.9%) were diabetic or prediabetic. More subjects reporting benefits had an endocrine-related comorbidity than those reporting injuries (40.1% vs. 16.0%, P benefit group than in the adverse event group ($83,846 vs. $70,378, P = 0.027). Of 75 subjects having adverse events, 8 (10.7%) had severe injuries, including fractures and head trauma, with 4 (5.3%) having inpatient stays. Most adverse events were musculoskeletal or skin injuries (n = 51, 68.0%). Injuries were similar to those seen with other light-to-moderate outdoor physical activities. Given KPNC's membership of 3.85 million, the number of severe injuries reported was low; this suggests that the game is safe to play. Pokémon Go may be reaching a population that requires increased physical activity.

Contribution à la connaissance du genre Asellus en Yougoslavie et en Turquie

NARCIS (Netherlands)

Deeleman-Reinhold, C.L.

1965-01-01

INTRODUCTION En 1962, 1963 et 1964, mon mari, Monsieur P. Robert Deeieman et moi, nous avons entrepris des voyages en Yougoslavie, dont le but principal fut la capture d'animaux cavernicoles. Dans les eaux souterraines et superficielles nous avons récolté cinq espèces du genre Asellus Geoffroy, dont

Entre o céu e a terra: a presença do além nas monções setecentistas

Directory of Open Access Journals (Sweden)

Mario Teixeira de Sá Junior

2011-01-01

Full Text Available The current article aims to introduce one of the many faces of the 1700’s monções in Mato Grosso. Thus, we intend to show the role of supernatural world with its characters, myths, phantoms and happenings in explaining the problems and solutions of monçoeiro daily life. The sources used are based on monçoeiros travelers’ stories and representatives of the Portuguese State, whose objective was to describe and to map the monçoeiras routes. / O presente artigo procura apresentar uma das muitas faces da história das monções setecentistas do Mato Grosso. Nele, será buscado apresentar o papel que o mundo sobrenatural com seus personagens, mitos, fantasmas e acontecimentos, desempenhou na explicação de problemas e soluções no cotidiano monçoeiro. As fontes utilizadas são baseadas em relatos de viajantes das monções e representantes do Estado Português, que buscavam descrever e mapear as rotas monçoeiras.

La stabilité monétaire comme culture ou comment penser l’ordre monétaire au prisme de la culture ? L’exemple allemand

OpenAIRE

Bellon, Charlotte

2017-01-01

L’objectif de cet article est de saisir la dimension culturelle de la convention monétaire. Les théories (hétérodoxes) de la monnaie ont ouvert la voie à l’analyse des manières dont la monnaie est acceptée comme moyen de paiement et de réserve. La monnaie devient alors l’expression (ou l’émanation) de l’ensemble du corps social. Elle incarne un collectif et, en ce sens, est dotée d’une signification symbolique, souvent saisie par les valeurs partagées au sein de la communauté monétaire. Cette...

Motives Matter: Motives for Playing Pokémon Go and Implications for Well-Being.

Science.gov (United States)

Yang, Chia-Chen; Liu, Dong

2017-01-01

Mobile games such as Pokémon Go have become a major form of entertainment, and yet little is known about why people play the games and how their motives associate with well-being. Although literature on motives for playing video and online games is informative, the findings may not reflect the full spectrum of mobile gaming motives due to some unique affordances of mobile games (e.g., mobility). To catch up with the evolving gaming context, a popular mobile game, Pokémon Go, was taken as an example to explore individuals' mobile gaming motives. A Pokémon Go Motive Scale was developed. Seven motives were identified through factor analyses based on survey data from 262 Pokémon Go players (45 percent women; M age  = 30.71, standard deviation = 7.77): Exercise, Fun, Escapism, Nostalgia, Friendship Maintenance, Relationship Initiation, and Achievement. Both Fun and Friendship Maintenance were positive correlates of well-being, whereas Escapism and Nostalgia were negative correlates. Relationship Initiation was associated with both better and poorer well-being. Implications of the findings are discussed.

Pokémon GO: gevangen in eigendom

NARCIS (Netherlands)

de Bruin, R.W.

2016-01-01

Pokémon Go is één van de eerste van een waarschijnlijk groot aantal (spel)omgevingen waar de werkelijke- en virtuele wereld met elkaar versmelten. In deze ‘hybride’ doen zich nieuwe rechtsvragen voor. Een klein aantal daarvan komt aan de orde orde in dit artikel. Vooralsnog lijkt het erop dat het

Mid-Infrared Observations of V838 Mon

OpenAIRE

A. M. Watson; L. Gómez; R. Costero

2006-01-01

Presentamos observaciones fotométricas de la estrella peculiar V838 Mon, entre 8 y 13 Um en bandas angostas, efectuadas en septiembre de 2002. El espectro es consistente con una ley de potencias, aunque un espectro con exceso de emisión entre 9 y 12 Um produce un mejor ajuste a los datos.

Arsia Mons Spiral Cloud

Science.gov (United States)

2002-01-01

One of the benefits of the Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) Extended Mission is the opportunity to observe how the planet's weather changes during a second full martian year. This picture of Arsia Mons was taken June 19, 2001; southern spring equinox occurred the same day. Arsia Mons is a volcano nearly large enough to cover the state of New Mexico. On this particular day (the first day of Spring), the MOC wide angle cameras documented an unusual spiral-shaped cloud within the 110 km (68 mi) diameter caldera--the summit crater--of the giant volcano. Because the cloud is bright both in the red and blue images acquired by the wide angle cameras, it probably consisted mostly of fine dust grains. The cloud's spin may have been induced by winds off the inner slopes of the volcano's caldera walls resulting from the temperature differences between the walls and the caldera floor, or by a vortex as winds blew up and over the caldera. Similar spiral clouds were seen inside the caldera for several days; we don't know if this was a single cloud that persisted throughout that time or one that regenerated each afternoon. Sunlight illuminates this scene from the left/upper left.Malin Space Science Systems and the California Institute of Technology built the MOC using spare hardware from the Mars Observer mission. MSSS operates the camera from its facilities in San Diego, CA. The Jet Propulsion Laboratory's Mars Surveyor Operations Project operates the Mars Global Surveyor spacecraft with its industrial partner, Lockheed Martin Astronautics, from facilities in Pasadena, CA and Denver, CO.

AppMon: Application Monitors for Not-Yet-Trusted Software

National Research Council Canada - National Science Library

Marceau, Carla; Kozen, Dexter

2007-01-01

Report developed under STTR contract for topic OSD06-SP2. AppMon represents a novel approach to monitoring the behavior of not-yet-trusted applications that avoids the disadvantages of current approaches...

Examining Motivations to Play Pokémon GO and Their Influence on Perceived Outcomes and Physical Activity.

Science.gov (United States)

Marquet, Oriol; Alberico, Claudia; Adlakha, Deepti; Hipp, J Aaron

2017-10-24

Pokémon GO is the most played augmented reality game in history. With more than 44 million players at the peak of its popularity, the game has sparked interest on its effects on the young population's health. This pilot study examined motivations to start playing Pokémon GO among a sample of US college students, and how motivations were associated with perceived outcomes of the playing experience and physical activity derived while playing. In November 2016, we asked a sample of 47 US college students (all Pokémon GO players) to complete online surveys and install an ecological momentary assessment (EMA) tool and step counter on their smartphones. The EMA tool prompted a set of questions on playing behavior and physical activity, 3 times per day (12:00 PM, 7:00 PM, and 10:00 PM), for 7 days. We used a factorial analysis to identify 3 distinctive groups of players based on their motivations to start playing Pokémon GO. We tested differences across motivation groups related to 5 unique outcomes using 1-way analysis of variance. We extracted 3 interpretable factors from the clustering of motivations to start playing Pokémon GO: Pokémon and video game fans (n=26, 55% of the sample), physical activity seekers (n=8, 17%), and curious & social (n=13, 28%). The clusters differed significantly on the enjoyment of different aspects of the game, particularly battling, discovering new places, and meeting new people, as well as differences in agreement that playing improved mood and made them more social. Days when playing Pokémon GO were associated with higher number of steps reported at the end of the day, especially among physical activity seekers, but also for Pokémon and video game fans. All groups perceived traffic as a major threat to playing. Days during which Pokémon GO was played were positively associated with a set of beneficial health behaviors, including higher physical activity levels, more socialization, and better mood. Results, however, depended on

KQ Mon and the nature of the UX Ursa Majoris nova-like variables

International Nuclear Information System (INIS)

Sion, E.M.; Guinan, E.F.

1983-01-01

New ultraviolet spectra of KQ Mon, a UX UMa type nova-like variable, are presented. The data derived from these spectra shed considerable light on its lack of major outbursts, a feature shared by other UX UMa stars, as well as on the absence of stellar winds in KQ Mon in contrast to the UX UMa stars. The author compares de-reddened continuum fluxes obtained from the data with values available from theoretical accretion disk models. A rather high steady accretion rate of 10 -8 solar masses per year turns out. This property seems to be responsible for their lack of major outbursts. 0ecause of a sub-critical value of the accretion flow, a wind outflow is absent in KQ Mon. The calculations are based on time-independent steady state disk structure. (G.J.P.)

Effect of chloride contamination in MON-1 propellant on crack growth properties of metals

Science.gov (United States)

Moran, C. M.; Toth, L. R.

1981-01-01

The effect of a high level of chloride content (800 ppm) in MON-1 propellant on the crack growth properties of seven materials was investigated. Sustained load tests were conducted at 49 C (120 F) temperature with thin gauge tensile specimens having a semi-elliptical surface flaw. Alloys included aluminum 1100, 3003, 5086 and 6061; corrosion resistant steel types A286 and 347; and titanium 6Al-4V. The configurations tested with precracked flaws exposed to MON-1 were: parent or base metal, center weld, and heat affected zone. It was concluded that this chloride level in MON-1 does not affect the stress corrosion, crack growth properties of these alloys after 1000 hour exposure duration under high stresses.

Genetic, serological and biochemical characterization of Leishmania tropica from foci in northern Palestine and discovery of zymodeme MON-307

Directory of Open Access Journals (Sweden)

Azmi Kifaya

2012-06-01

Full Text Available Abstract Background Many cases of cutaneous leishmaniasis (CL have been recorded in the Jenin District based on their clinical appearance. Here, their parasites have been characterized in depth. Methods Leishmanial parasites isolated from 12 human cases of CL from the Jenin District were cultured as promastigotes, whose DNA was extracted. The ITS1 sequence and the 7SL RNA gene were analysed as was the kinetoplast minicircle DNA (kDNA sequence. Excreted factor (EF serotyping and multilocus enzyme electrophoresis (MLEE were also applied. Results This extensive characterization identified the strains as Leishmania tropica of two very distinct sub-types that parallel the two sub-groups discerned by multilocus microsatellite typing (MLMT done previously. A high degree of congruity was displayed among the results generated by the different analytical methods that had examined various cellular components and exposed intra-specific heterogeneity among the 12 strains. Three of the ten strains subjected to MLEE constituted a new zymodeme, zymodeme MON-307, and seven belonged to the known zymodeme MON-137. Ten of the 15 enzymes in the profile of zymodeme MON-307 displayed different electrophoretic mobilities compared with the enzyme profile of the zymodeme MON-137. The closest profile to that of zymodeme MON-307 was that of the zymodeme MON-76 known from Syria. Strains of the zymodeme MON-307 were EF sub-serotype A2 and those of the zymodeme MON-137 were either A9 or A9B4. The sub-serotype B4 component appears, so far, to be unique to some strains of L. tropica of zymodeme MON-137. Strains of the zymodeme MON-137 displayed a distinctive fragment of 417 bp that was absent in those of zymodeme MON-307 when their kDNA was digested with the endonuclease RsaI. kDNA-RFLP after digestion with the endonuclease MboI facilitated a further level of differentiation that partially coincided with the geographical distribution of the human cases from which the strains

Mapping surrogate gasoline compositions into RON/MON space

NARCIS (Netherlands)

Morgan, N.; Smallbone, A.; Bhave, A.; Kraft, M.; Cracknell, R.; Kalghatgi, G.T.

2010-01-01

In this paper, new experimentally determined octane numbers (RON and MON) of blends of a tri-component surrogate consisting of toluene, n-heptane, i-octane (called toluene reference fuel TRF) arranged in an augmented simplex design are used to derive a simple response surface model for the octane

Pokémon GO and psychological distress, physical complaints, and work performance among adult workers: a retrospective cohort study.

Science.gov (United States)

Watanabe, Kazuhiro; Kawakami, Norito; Imamura, Kotaro; Inoue, Akiomi; Shimazu, Akihito; Yoshikawa, Toru; Hiro, Hisanori; Asai, Yumi; Odagiri, Yuko; Yoshikawa, Etsuko; Tsutsumi, Akizumi

2017-09-07

The effects of Pokémon GO, a new mobile game application which utilizes augmented reality, on risky behavior and health have already been discussed in anecdotal evidence. However, there have been no studies about its effects on mental health. This study investigated the relationships between Pokémon GO and psychological distress from an existing workers' cohort in Japan. Online surveys were conducted to 3,915 full-time workers, at baseline (Nov 26, 2015-Feb 18, 2016) and at follow-up (Dec 1-4, 2016), using a self-report questionnaire. Pokémon GO players were defined as participants who had played Pokémon GO for one month or longer. Psychological distress was measured using validated scales. Of the completers, 246 (9.7%) had continued to play Pokémon GO. They were significantly younger than non-players. From the results of the general linear modeling, improvement in psychological distress was significantly greater among Pokémon GO players than among non-players (p = 0.025). Cohen's d for the difference in psychological distress was -0.20 (95% CI, -0.33, -0.07). Pokémon GO may be effective for improving psychological distress among workers. Although its effect size is small, the game could have positive effects on the mental health of the adult working population.

Síntesis de nuevos monómeros para fotopolimerizaciones catiónicas

OpenAIRE

Acosta Ortiz, Ricardo; Crivello, James V.

2003-01-01

Se reportan los métodos de preparación de cinco nuevos monómeros susceptibles de ser fotopolimerizados catiónicamente. Estos incluyen compuestos del tipo epoxiciclohexano, vinil éter, propenil éter y oxetanos. La característica común de estos monómeros es que contienen en su estructura un grupo bencílico con sustituyentes donadores de electrones como los grupos metóxido o el grupo metilendioxolano. La síntesis de estos compuestos involucra reacciones de eterificación y oxidación. Se explica e...

MedMon: securing medical devices through wireless monitoring and anomaly detection.

Science.gov (United States)

Zhang, Meng; Raghunathan, Anand; Jha, Niraj K

2013-12-01

Rapid advances in personal healthcare systems based on implantable and wearable medical devices promise to greatly improve the quality of diagnosis and treatment for a range of medical conditions. However, the increasing programmability and wireless connectivity of medical devices also open up opportunities for malicious attackers. Unfortunately, implantable/wearable medical devices come with extreme size and power constraints, and unique usage models, making it infeasible to simply borrow conventional security solutions such as cryptography. We propose a general framework for securing medical devices based on wireless channel monitoring and anomaly detection. Our proposal is based on a medical security monitor (MedMon) that snoops on all the radio-frequency wireless communications to/from medical devices and uses multi-layered anomaly detection to identify potentially malicious transactions. Upon detection of a malicious transaction, MedMon takes appropriate response actions, which could range from passive (notifying the user) to active (jamming the packets so that they do not reach the medical device). A key benefit of MedMon is that it is applicable to existing medical devices that are in use by patients, with no hardware or software modifications to them. Consequently, it also leads to zero power overheads on these devices. We demonstrate the feasibility of our proposal by developing a prototype implementation for an insulin delivery system using off-the-shelf components (USRP software-defined radio). We evaluate its effectiveness under several attack scenarios. Our results show that MedMon can detect virtually all naive attacks and a large fraction of more sophisticated attacks, suggesting that it is an effective approach to enhancing the security of medical devices.

Entrevista a Santiago Álvarez de Mon

Directory of Open Access Journals (Sweden)

Sergio López

2006-09-01

Full Text Available Santiago Álvarez de Mon es un profesor de obligada referencia académica y profesional en el ámbito de los valores humanos en la alta dirección empresarial. Doctor en sociología y ciencias políticas por la Universidad de Salamanca (España, es profesor en el Instituto de Estudios Superiores de la Empresa de la Universidad de Navarra (IESE, actualmente considerada como una de las diez escuelas de negocios más prestigiosas del mundo. Álvarez de Mon es autor de varios artículos y libros sobre el liderazgo empresarial, entre los que destacan “El mito del líder” o “Desde la adversidad: liderazgo, cuestión de carácter”, basado en las historias de vida e investigación sobre destacados personajes como Nelson Mandela, Hellen Keller, José Carreras o Lance Armstrong, entre otros. Ha trabajado como directivo en la banca española, así como en el sector de grandes cadenas de distribución, y actualmente combina su labor docente con el asesoramiento a varias compañías en materias de liderazgo y trabajo en equipo.

Monitoring, accounting and automated decision support for the ALICE experiment based on the MonALISA framework

CERN Document Server

Cirstoiu, C; Betev, L; Saiz, P; Peters, A J; Muraru, A; Voicu, R; Legrand, I

2007-01-01

We are developing a general purpose monitoring system for the ALICE experiment, based on the MonALISA framework. MonALISA (Monitoring Agents using a Large Integrated Services Architecture) is a fully distributed system with no single point of failure that is able to collect, store monitoring information and present it as significant perspectives and synthetic views on the status and the trends of the entire system. Furthermore, agents can use it for taking automated operational decisions. Monitoring information is gathered locally from all the components running in each site. The entire flow of information is aggregated on site level by a MonALISA service and then collected and presented in various forms by a central MonALISA Repository. Based on this information, other services take operational decisions such as alerts, triggers, service restarts and automatic production job or transfer submissions. The system monitors all the components: computer clusters (all major parameters of each computing node), jobs ...

EFSA Panel on Genetically Modified Organisms (GMO); Scientific Opinion on application (EFSAGMO- NL-2007-39) for the placing on the market of insect resistant and herbicide tolerant genetically modified maize MON89034 x MON88017 for food and feed uses, import and processing under Regulation (EC

DEFF Research Database (Denmark)

Sørensen, Ilona Kryspin

This opinion reports on an evaluation of a risk assessment for placing on the market the genetically modified herbicide tolerant and insect resistant maize MON89034 x MON88017 for food and feed uses, import and processing. Conventional breeding methods were used in the production of maize MON89034...

Why the public health sector couldn’t create Pokémon Go

Directory of Open Access Journals (Sweden)

Becky Freeman

2017-07-01

Full Text Available Pokémon Go has been subject to much attention – from both the players that download the augmented reality game and the news media. Amid the exaggerated media reports, Pokémon Go may have unintended health benefits. Players have reported walking more, spending more time with family, experiencing improvements in their mental health and feeling more connected to their communities. It is hard to imagine public health researchers developing a similar game that is fun, taps into pop culture, reaches a wide target audience, makes use of physical and virtual environments, creates a sense of both competition and community, and has spin-off health benefits. Companies that endanger public health immediately recognised the value of the Pokémon Go app, and exploited it to advertise and promote consumption of unhealthy foods. Public health stakeholders need to develop mobile-based interventions within a framework that embraces pleasure, rewards, participation and community. Public health agencies need to be just as nimble and responsive as companies that are harmful to health, or forever be creating games that nobody plays.

Why the public health sector couldn't create Pokémon Go.

Science.gov (United States)

Freeman, Becky; Chau, Josephine; Mihrshahi, Seema

2017-07-26

Pokémon Go has been subject to much attention - from both the players that download the augmented reality game and the news media. Amid the exaggerated media reports, Pokémon Go may have unintended health benefits. Players have reported walking more, spending more time with family, experiencing improvements in their mental health and feeling more connected to their communities. It is hard to imagine public health researchers developing a similar game that is fun, taps into pop culture, reaches a wide target audience, makes use of physical and virtual environments, creates a sense of both competition and community, and has spin-off health benefits. Companies that endanger public health immediately recognised the value of the Pokémon Go app, and exploited it to advertise and promote consumption of unhealthy foods. Public health stakeholders need to develop mobile-based interventions within a framework that embraces pleasure, rewards, participation and community. Public health agencies need to be just as nimble and responsive as companies that are harmful to health, or forever be creating games that nobody plays.

Mercurious Oil Index (MOI) : A new indicator for the global oil price

OpenAIRE

Leeuw, de, J.; Dorsman, A.B.; Nelissen, R.

2008-01-01

“The” price of oil does not exist. This paper describes the development of a (new) oil index, the Mercurious Oil Index (MOI). This index can be seen as an indicator for the global price of oil. We will discuss why this index is a reliable global price reference, and why it is superior to and more useful than the existing indices and/or benchmarks. Indices are very helpful instruments for the tracking and prediction of markets, to measure performance or sentiment and to form a solid basis on w...

Deux voyages d’hiver

Directory of Open Access Journals (Sweden)

Etienne Barilier

2011-12-01

Full Text Available La relation entre la vie et l’œuvre, chez un artiste, n’est jamais une simple relation de cause à effet. L’on peut trouver, à l’origine du Voyage d’hiver de Schubert, comme à celle de la Rhapsodie pour alto de Brahms (dont les paroles, tirées d’un poème de Goethe, racontent elles aussi un voyage hivernal, des douleurs amoureuses. Mais ces deux œuvres transcendent les événements biographiques dont elles sont issues. échappant au narcissisme du moi romantique, elles traduisent deux expériences du temps, cyclique ou progressif, racontent deux voyages spirituels. La douleur d’exister y devient pure présence de la vie, et récit purifié.For an artist, the link between life and work is never a simple cause-effect relationship. The loving pain can be considered as the source of Schubert's Winterreise and of the Brahms Alto Rhapsody as well (the latter being based also upon a poem by Goethe, which tells also a winter journey. But these works transcend the life events from which they arise. Beyond the narcissism of the romantic self, they reflect two experiences of time, cyclical or progressive, and they tell two spiritual journeys. The pain of existence becomes a pure presence of life, and a purified story.

Genetic structure of the Mon-Khmer speaking groups and their affinity to the neighbouring Tai populations in Northern Thailand

OpenAIRE

Kutanan, Wibhu; Kampuansai, Jatupol; Fuselli, Silvia; Nakbunlung, Supaporn; Seielstad, Mark; Bertorelle, Giorgio; Kangwanpong, Daoroong

2011-01-01

Abstract Background The Mon-Khmer speaking peoples inhabited northern Thailand before the arrival of the Tai speaking people from southern China in the thirteenth century A.D. Historical and anthropological evidence suggests a close relationship between the Mon-Khmer groups and the present day majority northern Thai groups. In this study, mitochondrial and Y-chromosomal DNA polymorphisms in more than 800 volunteers from eight Mon-Khmer and ten Tai speaking populations were investigated to est...

A Comparison and Analog-Based Analysis of Sinuous Channels on the Rift Aprons of Ascraeus Mons and Pavonis Mons Volcanoes, Mars

Science.gov (United States)

Collins, A.; de Wet, A.; Bleacher, J.; Schierl, Z.; Schwans, B.

2012-01-01

The origin of sinuous channels on the flanks of the Tharsis volcanoes on Mars is debated among planetary scientists. Some argue a volcanic genesis [1] while others have suggested a fluvial basis [2-4]. The majority of the studies thus far have focused on channels on the rift apron of Ascraeus Mons. Here, however, we broadly examine the channels on the rift apron of Pavonis Mons and compare them with those studied channels around Ascraeus. We compare the morphologies of features from both of these volcanoes with similar features of known volcanic origin on the island of Hawai i. We show that the morphologies between these two volcanoes in the Tharsis province are very similar and were likely formed by comparable processes, as previous authors have suggested [5]. We show that, although the morphologies of many of the channels around these volcanoes show some parallels to terrestrial fluvial systems, these morphologies can also be formed by volcanic processes. The context of these features suggests that volcanic processes were the more likely cause of these channels.

Gotta catch'em all! Pokémon GO and physical activity among young adults: difference in differences study.

Science.gov (United States)

Howe, Katherine B; Suharlim, Christian; Ueda, Peter; Howe, Daniel; Kawachi, Ichiro; Rimm, Eric B

2016-12-13

 To estimate the effect of playing Pokémon GO on the number of steps taken daily up to six weeks after installation of the game.  Cohort study using online survey data.  Survey participants of Amazon Mechanical Turk (n=1182) residing in the United States, aged 18 to 35 years and using iPhone 6 series smartphones.  Number of daily steps taken each of the four weeks before and six weeks after installation of Pokémon GO, automatically recorded in the "Health" application of the iPhone 6 series smartphones and reported by the participants. A difference in difference regression model was used to estimate the change in daily steps in players of Pokémon GO compared with non-players.  560 (47.4%) of the survey participants reported playing Pokémon GO and walked on average 4256 steps (SD 2697) each day in the four weeks before installation of the game. The difference in difference analysis showed that the daily average steps for Pokémon GO players during the first week of installation increased by 955 additional steps (95% confidence interval 697 to 1213), and then this increase gradually attenuated over the subsequent five weeks. By the sixth week after installation, the number of daily steps had gone back to pre-installation levels. No significant effect modification of Pokémon GO was found by sex, age, race group, bodyweight status, urbanity, or walkability of the area of residence.  Pokémon GO was associated with an increase in the daily number of steps after installation of the game. The association was, however, moderate and no longer observed after six weeks. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Potential perils of peri-Pokémon perambulation: the dark reality of augmented reality?

Science.gov (United States)

Joseph, Bellal; Armstrong, David G

2016-10-01

Recently, the layering of augmented reality information on top of smartphone applications has created unprecedented user engagement and popularity. One augmented reality-based entertainment application, Pokémon Go (Pokémon Company, Tokyo, Japan) has become the most rapidly downloaded in history. This technology holds tremendous promise to promote ambulatory activity. However, there exists the obvious potential for distraction-related morbidity. We report two cases, presenting simultaneously to our trauma center, with injuries sustained secondary to gameplay with this augmented reality-based application.

The Distance to Nova V959 Mon from VLA Imaging

Science.gov (United States)

Linford, J. D.; Ribeiro, V. A. R. M.; Chomiuk, L.; Nelson, T.; Sokoloski, J. L.; Rupen, M. P.; Mukai, K.; O'Brien, T. J.; Mioduszewski, A. J.; Weston, J.

2015-06-01

Determining reliable distances to classical novae is a challenging but crucial step in deriving their ejected masses and explosion energetics. Here we combine radio expansion measurements from the Karl G. Jansky Very Large Array with velocities derived from optical spectra to estimate an expansion parallax for nova V959 Mon, the first nova discovered through its γ-ray emission. We spatially resolve the nova at frequencies of 4.5-36.5 GHz in nine different imaging epochs. The first five epochs cover the expansion of the ejecta from 2012 October to 2013 January, while the final four epochs span 2014 February-May. These observations correspond to days 126 through 199 and days 615 through 703 after the first detection of the nova. The images clearly show a non-spherical ejecta geometry. Utilizing ejecta velocities derived from three-dimensional modeling of optical spectroscopy, the radio expansion implies a distance between 0.9 ± 0.2 and 2.2 ± 0.4 kpc, with a most probable distance of 1.4 ± 0.4 kpc. This distance implies a γ-ray luminosity of 0.6× {{10}35} erg s-1, which is much less than the prototype γ-ray-detected nova, V407 Cyg, possibly due to the lack of a red giant companion in the V959 Mon system. V959 Mon also has a much lower γ-ray luminosity than other classical novae detected in γ-rays to date, indicating a range of at least a factor of 10 in the γ-ray luminosities for these explosions.

SiMon: Simulation Monitor for Computational Astrophysics

Science.gov (United States)

Xuran Qian, Penny; Cai, Maxwell Xu; Portegies Zwart, Simon; Zhu, Ming

2017-09-01

Scientific discovery via numerical simulations is important in modern astrophysics. This relatively new branch of astrophysics has become possible due to the development of reliable numerical algorithms and the high performance of modern computing technologies. These enable the analysis of large collections of observational data and the acquisition of new data via simulations at unprecedented accuracy and resolution. Ideally, simulations run until they reach some pre-determined termination condition, but often other factors cause extensive numerical approaches to break down at an earlier stage. In those cases, processes tend to be interrupted due to unexpected events in the software or the hardware. In those cases, the scientist handles the interrupt manually, which is time-consuming and prone to errors. We present the Simulation Monitor (SiMon) to automatize the farming of large and extensive simulation processes. Our method is light-weight, it fully automates the entire workflow management, operates concurrently across multiple platforms and can be installed in user space. Inspired by the process of crop farming, we perceive each simulation as a crop in the field and running simulation becomes analogous to growing crops. With the development of SiMon we relax the technical aspects of simulation management. The initial package was developed for extensive parameter searchers in numerical simulations, but it turns out to work equally well for automating the computational processing and reduction of observational data reduction.

From History to Memory: Alain Resnais’ and Marguerite Duras’ Hiroshima mon amour

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Sarah French

2008-12-01

Full Text Available This paper examines the representation of history and memory in Alain Resnais’ and Marguerite Duras’ 1959 film Hiroshima mon amour. It argues that the film’s privileging of subjective remembrance reflects a broader cultural interest in using memory as a counter discourse to established history. The widely documented cultural preoccupation with memory became particularly prominent in the early 1980s. However, Hiroshima mon amour can be read as an important early example of a film that predates the contemporary ‘memory boom’. For Resnais and Duras, the magnitude of the devastation in Hiroshima exceeds the limits of filmic representation. Their solution to the problem that the historic event is unrepresentable is to approach the event indirectly while focusing on an individual traumatic memory. Through a close analysis and critique of the film I argue that the film’s emphasis on individual memory validates the legitimacy of the personal narrative but problematically subsumes the political events and displaces history from the discursive realm. I also suggest that problems emerge in the film’s depiction of its traumatised female subject. While Hiroshima mon amour represents a complex female subjectivity and interiority, the process of remembrance depicted deprives the woman of agency and renders her trapped within a compulsive repetition of the past.

A NEW RADIO RECOMBINATION LINE MASER OBJECT TOWARD THE MonR2 H II REGION

Energy Technology Data Exchange (ETDEWEB)

Jimenez-Serra, I.; Zhang, Q.; Dierickx, M.; Patel, N. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Baez-Rubio, A.; Rivilla, V. M.; Martin-Pintado, J., E-mail: ijimenez-serra@cfa.harvard.edu, E-mail: qzhang@cfa.harvard.edu, E-mail: mdierickx@cfa.harvard.edu, E-mail: npatel@cfa.harvard.edu, E-mail: ryvendel@gmail.com, E-mail: jmartin@cab.inta-csic.es, E-mail: baezra@cab.inta-csic.es [Centro de Astrobiologia (CSIC/INTA), Ctra. de Torrejon a Ajalvir km 4, E-28850 Torrejon de Ardoz, Madrid (Spain)

2013-02-10

We report the detection of a new radio recombination line (RRL) maser object toward the IRS2 source in the MonR2 ultracompact H II region. The continuum emission at 1.3 mm and 0.85 mm and the H30{alpha} and H26{alpha} lines were observed with the Submillimeter Array (SMA) at angular resolutions of {approx}0.''5-3''. The SMA observations show that the MonR2-IRS2 source is very compact and remains unresolved at spatial scales {<=}400 AU. Its continuum power spectrum at millimeter wavelengths is almost flat ({alpha} = -0.16, with S{sub {nu}}{proportional_to}{nu}{sup {alpha}}), indicating that this source is dominated by optically thin free-free emission. The H30{alpha} and H26{alpha} RRL emission is also compact and peaks toward the position of the MonR2-IRS2 source. The measured RRL profiles are double peaked with the H26{alpha} line showing a clear asymmetry in its spectrum. Since the derived line-to-continuum flux ratios ({approx}80 and 180 km s{sup -1} for H30{alpha} and H26{alpha}, respectively) exceed the LTE predictions, the RRLs toward MonR2-IRS2 are affected by maser amplification. The amplification factors are, however, smaller than those found toward the emission-line star MWC349A, indicating that MonR2-IRS2 is a weakly amplified maser. Radiative transfer modeling of the RRL emission toward this source shows that the RRL masers arise from a dense and collimated jet embedded in a cylindrical ionized wind, oriented nearly along the direction of the line of sight. High-angular resolution observations at submillimeter wavelengths are needed to unveil weakly amplified RRL masers in very young massive stars.

"Pokémon Go!" May Promote Walking, Discourage Sedentary Behavior in College Students.

Science.gov (United States)

Barkley, Jacob E; Lepp, Andrew; Glickman, Ellen L

2017-06-01

To assess self-reported walking and sedentary behavior in young adults before and after downloading "Pokémon Go!". In September 2016, a sample of 358 (19.8 ± 2.1 years old, n = 187 females) college students who had downloaded "Pokémon Go!" on their cellular telephones (i.e., cell phones) were surveyed for weekly walking and sedentary behavior via the International Physical Activity Questionnaire. A single interview was administered to participants who estimated their walking and sedentary behavior at three time points: the week immediately preceding their download of "Pokémon Go!" (Baseline), the first week after downloading the game (Time 1), and the week the survey was completed (Time 2). Differences in self-reported physical activity and sedentary behavior across the three time points and across the two genders were compared via analyses of variance. There was a significant main effect of time (F ≥ 49.3, P ≤ 0.001) for walking and sedentary behavior. Participants reported greater (t ≥ 9.5, P games hold promise as technology that may promote physical activity and discourage sedentary behavior.

Cyrano, la république et la révolution d’Angleterre

Directory of Open Access Journals (Sweden)

Didier Kahn

2010-01-01

Full Text Available Dans la Lune, le héros des États et Empires de la Lune rencontre le Démon de Socrate, et celui-ci lui raconte ses diverses apparitions sur Terre parmi les hommes. Après la mort de Socrate, commence-t-il, il a jadis « gouverné et instruit, à Thèbes, Épaminondas » ; « étant passé [ensuite] chez les Romains, la justice [l’a] attaché au parti du jeune Caton ; puis après son trépas, [il s’est] donné à Brutus ». Enfin, « tous ces grands personnages n’ayant rien laissé au monde à leur place que l’im...

Mars - Stratigraphy and gravimetry of Olympus Mons and its aureole

Science.gov (United States)

Hiller, K. H.; Neukum, G. P. O.; Janle, P.; Guest, J. E.; Lopes, R. M. C.

1982-01-01

The relative ages of the major geologic units on and around Olympus Mons are considered, together with an interpretation of the gravity anomaly found for this area. The crater data for this investigation have been acquired and interpreted according to the method outlined by Neukum and Hiller (1981). After careful geological mapping, craters clearly identified as impacts are measured and counted. Crater frequency values per sq km for craters greater than or equal to 1 km ('crater retention ages') are read from the individual counts by fitting the Martian cumulative crater production size-frequency distribution to the individual counts. In addition to age dating, the problem of the origin and nature of the aureole materials using gravity data is addressed. This is done by determining whether the line-of-sight gravity extending from Olympus Mons to the northwestern part of the aureole can be explained by the aureole masses alone or whether additional high-density intrusive masses must be assumed in the aureola area.

Development and Evaluation of Event-Specific Quantitative PCR Method for Genetically Modified Soybean MON87701.

Science.gov (United States)

Tsukahara, Keita; Takabatake, Reona; Masubuchi, Tomoko; Futo, Satoshi; Minegishi, Yasutaka; Noguchi, Akio; Kondo, Kazunari; Nishimaki-Mogami, Tomoko; Kurashima, Takeyo; Mano, Junichi; Kitta, Kazumi

2016-01-01

A real-time PCR-based analytical method was developed for the event-specific quantification of a genetically modified (GM) soybean event, MON87701. First, a standard plasmid for MON87701 quantification was constructed. The conversion factor (C f ) required to calculate the amount of genetically modified organism (GMO) was experimentally determined for a real-time PCR instrument. The determined C f for the real-time PCR instrument was 1.24. For the evaluation of the developed method, a blind test was carried out in an inter-laboratory trial. The trueness and precision were evaluated as the bias and reproducibility of relative standard deviation (RSDr), respectively. The determined biases and the RSDr values were less than 30 and 13%, respectively, at all evaluated concentrations. The limit of quantitation of the method was 0.5%, and the developed method would thus be applicable for practical analyses for the detection and quantification of MON87701.

Pokémon GO: Implications for Literacy in the Classroom

Science.gov (United States)

Howell, Emily

2017-01-01

This teaching tip gives teachers practical applications of the game Pokémon GO for literacy teaching and learning. The author discusses applications of the game for teaching multimodality in upper elementary-school classrooms. The author situates these applications in relevant theoretical perspectives as well as current literacy research.

Reality has always been augmented: Play and the promises of Pokémon GO

DEFF Research Database (Denmark)

Sicart, Miguel Angel

2016-01-01

This piece provides an explanation to the early success of Pokémon GO. It proposes an argument about how this game exemplifies a computational culture of play. By drawing on philosophy of technology (Floridi, 2013) and game design research (Montola, Stenros, & Waern, 2009), this article argues...... that the success of Pokémon GO is the result of the development of a play experience and a computational interface for a reality that is already augmented. These interfaces open new possibilities for digital play in public, but they also raise concerns regarding corporate appropriation of public spaces....

FACTORS AFFECTING IMPLEMENTATION OF EVIDENCE BASED PRACTICE AMONG PHYSIOTHERAPISTS IN MOI TEACHING REFFERAL HOSPITAL KENYA

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Naomi Wanjiru

2016-06-01

Full Text Available Background: The application of the concept of Evidenced Based Practice into clinical decision-making and practicehas outstanding benefits both to clinicians and the patient. However, the utilization of this concept has not been copiously utilized in most health facilities by the physiotherapists in Kenya. Therefore, the objectives for this study was to determine the level of awareness of evidence based practice among Physiotherapist, establish the availability of resource for Evidence Based Practice and to assess the challenges encountered by physiotherapist in engaging in evidence based practice at Moi Teaching and Referral Hospital. Methods: All physiotherapists working in Moi Teaching and Referral Hospital (42 took part in a cross-sectional descriptive survey. Questionnaires were used for data collection and analyzed by SPSS version 22. Results: there was high level of awareness on Evidence Based Practice (95 % and confidence in EBP (72.5 %. However, lack of information resources, poor skills to implement EBP, poor organization support 90%, insufficient authority to induct change in the practice setting 85%, inadequate facilities 74% and lack of time were identified as the major challenges in implementation of EBP Conclusion: Strategies should be developed to provide PTs with EBP resources, such as access to databases or links to guidelines, and continuous education regarding specific topics. Professional organizations and Associations should aim at changing the current practice to ensure full utilization of EBP.

Pokémon-Go: Why Augmented Reality Games Offer Insights for Enhancing Public Health Interventions on Obesity-Related Diseases.

Science.gov (United States)

Wong, Ming Chao; Turner, Paul; MacIntyre, Kate; Yee, Kwang Chien

2017-01-01

Stimulating widespread interests of the population to participate in behavioural changes through information and technology has been an aim of much health informatics research. The recent widespread participation of the augmented reality game Pokémon Go which encourages exercises, provides significant insights into the potential of information technology to improve healthcare intervention on obesity-related disease. Does Pokémon Go point to another way of achieving health benefits using mobile devices? This paper analyses the features of Pokémon Go in relation to potential health benefits. This paper suggests from the perspective of a user on changes to the game that potentially could help with obesity, mental health cardiovascular health and vitamin D deficiencies. While the impact of augmented reality games on improving exercises might be substantial, the question of sustainability and likely long-term health outcomes remain debatable. The rapid uptake of Pokémon Go by the population around the world, however, should serve as a useful lesson for information and technological design to improve outcomes obesity-related diseases in the future.

De la circulation des "locis sanctis" - le Mons Sion a Prague

Czech Academy of Sciences Publication Activity Database

Benešovská, Klára

2014-01-01

Roč. 1, č. 1 (2014), s. 50-62 ISSN 2336-3452 R&D Projects: GA ČR GA13-39192S Institutional support: RVO:68378033 Keywords : Mons Sion * Jindřich Zdík * Strahov * pilgrimage * Jerusalem * Holy Sepulchre Subject RIV: AL - Art, Architecture, Cultural Heritage

Considerações sobre eu e o corpo em Lacan Some considerations about the moi and the body in Lacan

Directory of Open Access Journals (Sweden)

Michele Cukiert

2002-01-01

Full Text Available O artigo trata da problemática do eu e do corpo em Lacan, articulados a partir de sua releitura do texto freudiano. Aponta como o autor, interrogando-se sobre a gênese do eu, retoma conceitos freudianos fundamentais tais como ego, identificação e narcisismo. Dessa forma, por meio da elaboração do registro do Imaginário e do esquema conceitual proposto pelo estádio do espelho, afirma a importância da imagem do corpo próprio na formação do eu, marcando também o desconhecimento e a alienação como constitutivos do eu. Indica como as noções de eu e de corpo sofrem transformações correlativas às retificações que Lacan opera em sua teoria, articulando-se também ao Simbólico e ao Real. Assim, no interior do campo psicanalítico delimitado pelo autor, o corpo pode ser pensado e estudado a partir de sua concepção dos três registros fundamentais: do ponto de vista do Imaginário, o corpo como imagem, do ponto de vista do Simbólico, o corpo marcado pelo significante, e do ponto de vista do Real, o corpo como sinônimo de gozo. Retoma a novidade freudiana acerca da corporeidade, afirmando que o corpo em Psicanálise não se reduz ao campo da Biologia. Finalmente, discute de que forma a teoria lacaniana possibilita repensar essa problemática a partir da linguagem.This article covers the issue of the moi and the body in Lacan, based on his re-reading of Freudian texts. It indicates how the author, questioning the constitution of the moi, goes back to Freudian fundamental concepts such as ego, identification and narcissism. In this way, through the elaboration of the Imaginary level and the proposed conceptual scheme of the mirror stage, it assures the importance of the image of the body in the formation of the moi, making also the unknown and the alienation as constituents of the moi. It indicates how the notions of the moi and the body suffer correlative transformations by the rectifications in Lacan's theory, as do the Symbolic

Genetic structure of the Mon-Khmer speaking groups and their affinity to the neighbouring Tai populations in Northern Thailand.

Science.gov (United States)

Kutanan, Wibhu; Kampuansai, Jatupol; Fuselli, Silvia; Nakbunlung, Supaporn; Seielstad, Mark; Bertorelle, Giorgio; Kangwanpong, Daoroong

2011-06-15

The Mon-Khmer speaking peoples inhabited northern Thailand before the arrival of the Tai speaking people from southern China in the thirteenth century A.D. Historical and anthropological evidence suggests a close relationship between the Mon-Khmer groups and the present day majority northern Thai groups. In this study, mitochondrial and Y-chromosomal DNA polymorphisms in more than 800 volunteers from eight Mon-Khmer and ten Tai speaking populations were investigated to estimate the degree of genetic divergence between these major linguistic groups and their internal structure. A large fraction of genetic variation is observed within populations (about 80% and 90% for mtDNA and the Y-chromosome, respectively). The genetic divergence between populations is much higher in Mon-Khmer than in Tai speaking groups, especially at the paternally inherited markers. The two major linguistic groups are genetically distinct, but only for a marginal fraction (1 to 2%) of the total genetic variation. Genetic distances between populations correlate with their linguistic differences, whereas the geographic distance does not explain the genetic divergence pattern. The Mon-Khmer speaking populations in northern Thailand exhibited the genetic divergence among each other and also when compared to Tai speaking peoples. The different drift effects and the post-marital residence patterns between the two linguistic groups are the explanation for a small but significant fraction of the genetic variation pattern within and between them. © 2011 Kutanan et al; licensee BioMed Central Ltd.

False Color Image of Volcano Sapas Mons

Science.gov (United States)

1991-01-01

This false-color image shows the volcano Sapas Mons, which is located in the broad equatorial rise called Atla Regio (8 degrees north latitude and 188 degrees east longitude). The area shown is approximately 650 kilometers (404 miles) on a side. Sapas Mons measures about 400 kilometers (248 miles) across and 1.5 kilometers (0.9 mile) high. Its flanks show numerous overlapping lava flows. The dark flows on the lower right are thought to be smoother than the brighter ones near the central part of the volcano. Many of the flows appear to have been erupted along the flanks of the volcano rather than from the summit. This type of flank eruption is common on large volcanoes on Earth, such as the Hawaiian volcanoes. The summit area has two flat-topped mesas, whose smooth tops give a relatively dark appearance in the radar image. Also seen near the summit are groups of pits, some as large as one kilometer (0.6 mile) across. These are thought to have formed when underground chambers of magma were drained through other subsurface tubes and lead to a collapse at the surface. A 20 kilometer-diameter (12-mile diameter) impact crater northeast of the volcano is partially buried by the lava flows. Little was known about Atla Regio prior to Magellan. The new data, acquired in February 1991, show the region to be composed of at least five large volcanoes such as Sapas Mons, which are commonly linked by complex systems of fractures or rift zones. If comparable to similar features on Earth, Atla Regio probably formed when large volumes of molten rock upwelled from areas within the interior of Venus known as'hot spots.' Magellan is a NASA spacecraft mission to map the surface of Venus with imaging radar. The basic scientific instrument is a synthetic aperture radar, or SAR, which can look through the thick clouds perpetually shielding the surface of Venus. Magellan is in orbit around Venus which completes one turn around its axis in 243 Earth days. That period of time, one Venus day

The Praise and Price of Pokémon GO: A Qualitative Study of Children’s and Parents’ Experiences

Science.gov (United States)

Castelli, Darla; Hallberg, Josef; Rutberg, Stina

2018-01-01

Background Physical activity has multiple health benefits; however, the majority of children around the world do not attain the recommended levels of daily physical activity. Research has shown that the game Poké mon GO has increased the amount of physical activity of players and that the game has the potential to reach populations that traditionally have low levels of physical activity. Therefore, there is a need to understand which game components can promote initial and sustained physical activity. By using a qualitative research approach, it is possible to achieve rich descriptions and enhance a deep understanding of the components promoting physical activity among children in a game such as Poké mon GO. Objective The objective of this study was to explore children’s and parents’ experiences playing Poké mon GO. Methods Eight families comprising 13 children (aged 7-12 years) and 9 parents were selected using purposeful sampling. Data collected using focus groups were analyzed using qualitative latent content analysis. Results The following three themes were revealed: (1) exciting and enjoyable exploration; (2) dangers and disadvantages; and (3) cooperation conquers competition. The first centers around the present and possible future aspects of Poké mon GO that promote physical activity. The second focuses on unwanted aspects and specific threats to safety when playing the game. The third shows that cooperation and togetherness are highly valued by the participants and that competition is fun but less important. Conclusions Components from Poké mon GO could enhance the efficacy of physical activity interventions. Cooperation and exploration are aspects of the game that preferably could be transferred into interventions aimed at promoting children’s physical activity. PMID:29298750

Intelligent MONitoring System for antiviral pharmacotherapy in patients with chronic hepatitis C (SiMON-VC

Directory of Open Access Journals (Sweden)

Luis Margusino-Framiñán

2017-01-01

Full Text Available Two out of six strategic axes of pharmaceutical care in our hospital are quality and safety of care, and the incorporation of information technologies. Based on this, an information system was developed in the outpatient setting for pharmaceutical care of patients with chronic hepatitis C, SiMON-VC, which would improve the quality and safety of their pharmacotherapy. The objective of this paper is to describe requirements, structure and features of Si- MON-VC. Requirements demanded were that the information system would enter automatically all critical data from electronic clinical records at each of the visits to the Outpatient Pharmacy Unit, allowing the generation of events and alerts, documenting the pharmaceutical care provided, and allowing the use of data for research purposes. In order to meet these requirements, 5 sections were structured for each patient in SiMON-VC: Main Record, Events, Notes, Monitoring Graphs and Tables, and Follow-up. Each section presents a number of tabs with those coded data needed to monitor patients in the outpatient unit. The system automatically generates alerts for assisted prescription validation, efficacy and safety of using antivirals for the treatment of this disease. It features a completely versatile Indicator Control Panel, where temporary monitoring standards and alerts can be set. It allows the generation of reports, and their export to the electronic clinical record. It also allows data to be exported to the usual operating systems, through Big Data and Business Intelligence. Summing up, we can state that SiMON-VC improves the quality of pharmaceutical care provided in the outpatient pharmacy unit to patients with chronic hepatitis C, increasing the safety of antiviral therapy.

EFSA Panel on Genetically Modified Organisms (GMO); Scientific Opinion on an application (EFSAGMO-NL-2012-107) for the placing on the market of maize MON 810 pollen under Regulation (EC) No 1829/2003 from Monsanto

DEFF Research Database (Denmark)

Sørensen, Ilona Kryspin

In this opinion, the EFSA GMO Panel addresses the safety of maize MON 810 pollen to complete the scope of an application (RX-MON 810) for the marketing of genetically modified maize MON 810 with the use of MON 810 pollen as or in food. Data on molecular characterisation of maize MON 810 did...... apply to the Cry1Ab protein expressed in MON 810 pollen. While the EFSA GMO Panel is not in a position to conclude on the safety of maize pollen in or as food in general, it concludes that the genetic modification in maize MON 810 does not constitute an additional health risk if maize MON 810 pollen...

The Mons Rümker volcanic complex of the Moon: A candidate landing site for the Chang'E-5 mission

Science.gov (United States)

Zhao, Jiannan; Xiao, Long; Qiao, Le; Glotch, Timothy D.; Huang, Qian

2017-07-01

Mons Rümker is a large volcanic complex in Oceanus Procellarum on the Moon and is a candidate landing site for China's Chang'E-5 sample return mission. We conducted a comprehensive study of the topography, geomorphology, composition, and stratigraphy of the Mons Rümker region with multisource remote sensing data in order to better understand the geology of the region and provide further support for the Chang'E-5 mission. The results show that the Rümker plateau stands 200-1300 m above the surrounding mare surface and 75% of the plateau has a slope of less than 3° at a baseline length of 30 m. Domes are the most prominent volcanic landforms in Mons Rümker and a total of 22 domes were identified and divided into two types that may represent different stages of volcanic activity. Spectral analyses indicated that Mons Rümker is covered by low-Ti basalt and the dominant mafic mineral is high-calcium pyroxene, though signs of mixing of highland materials and basalt have been found. Mons Rümker has three main basalt units, and their absolute model ages are 3.71 Ga, 3.58 Ga, and 3.51 Ga, respectively. Steep-sided domes could be the youngest volcanic features on the plateau with indications that they were active until the Eratosthenian. A new geologic map of the study region was produced and used to interpret and discuss the geologic evolution of the region. Finally, we propose two candidate landing sites for the Chang'E-5 mission.

A simplified and accurate detection of the genetically modified wheat MON71800 with one calibrator plasmid.

Science.gov (United States)

Kim, Jae-Hwan; Park, Saet-Byul; Roh, Hyo-Jeong; Park, Sunghoon; Shin, Min-Ki; Moon, Gui Im; Hong, Jin-Hwan; Kim, Hae-Yeong

2015-06-01

With the increasing number of genetically modified (GM) events, unauthorized GMO releases into the food market have increased dramatically, and many countries have developed detection tools for them. This study described the qualitative and quantitative detection methods of unauthorized the GM wheat MON71800 with a reference plasmid (pGEM-M71800). The wheat acetyl-CoA carboxylase (acc) gene was used as the endogenous gene. The plasmid pGEM-M71800, which contains both the acc gene and the event-specific target MON71800, was constructed as a positive control for the qualitative and quantitative analyses. The limit of detection in the qualitative PCR assay was approximately 10 copies. In the quantitative PCR assay, the standard deviation and relative standard deviation repeatability values ranged from 0.06 to 0.25 and from 0.23% to 1.12%, respectively. This study supplies a powerful and very simple but accurate detection strategy for unauthorized GM wheat MON71800 that utilizes a single calibrator plasmid. Copyright © 2014 Elsevier Ltd. All rights reserved.

Láser de monóxido de carbono : Estudio espectroscópico del sistema Angstrom

OpenAIRE

Schinca, Daniel Carlos

1985-01-01

En el presente trabajo se intenta resumir la labor desarrollada en láseres gaseosos de moléculas diatómicas de excitación pulsada, particularmente en lo que respecta a láseres de monóxido de carbono de geometría axial. De esta manera, se realiza un detallado análisis espectroscópico tanto de la salida láser de las bandas de emisión del Sistema Angstrom como de la emisión espontánea de las mismas bajo diferentes condiciones experimentales. Es sabido que la molécula de monóxido de car...

28 milliards d’euros, c’est grand comment ?

OpenAIRE

Ozer, Pierre; Salmon, Marc; Theunissen, Yannick

2009-01-01

J’ouvre mon quotidien. Fortis : 28 milliards d’euros de pertes en 2008. Ma fille de sept ans qui commence à lire et pose sans cesse des questions sur tout me lance : « Dis-moi, papa : 28 milliards d’euros, c’est grand comment ? ». Grande question… Je réfléchis et tente de trouver une parade parlante pour un enfant qui, in fine, se pose les mêmes questions que les grandes personnes.

Videogame-Related Illness and Injury: A Review of the Literature and Predictions for Pokémon GO!

Science.gov (United States)

Pourmand, Ali; Lombardi, Kevin; Kuhl, Evan; O'Connell, Francis

2017-02-01

Reports of videogame-related illness and injury soon emerged in the literature with the inception of videogame systems and subsequent development of novel gaming platforms and technologies. In an effort to better detail the impacts of these phenomena and provide recommendations for injury prevention as it relates to Pokémon Go and the larger world of augmented reality games, we conducted an extensive systems-based review of past trends in videogame-related illness and injury from the literature. A literature review using PubMed, Medline, and PsycInfo databases with search terms "Pokémon GO," "videogame injuries," "augmented reality injuries," and "Nintendo Injury" was performed. The search was limited to the English language, and the Boolean were used to combine the search terms. The literature search yielded 359 peer-reviewed articles, 44 of which met the study criteria and included in the review. Seventeen additional popular press reports detailing injuries related to Pokémon Go were also incorporated. Videogame-related injuries and illness include both physical trauma as well as psychological and behavioral disorder with unique patterns of injury and illness linked to specific gaming platforms. As videogames become increasingly advanced and immersive, they expose players to unique and often more serious injury and illness. Augmented reality games, such as Pokémon GO, are the next step in the evolution of this trend and likely portend a future in which many pathologic processes may become increasingly common.

Des colonies à l’Empire fasciste. La conquête de l’Afrique racontée aux enfants italiens

Directory of Open Access Journals (Sweden)

Mariella Colin

2012-01-01

Full Text Available En Italie, la conquête et la colonisation de l’Afrique se sont inscrites dans la littérature pour l’enfance au fur et à mesure de l’occupation des territoires, en correspondance avec l’évolution idéologique qui l’accompagna. Dans les dernières décennies du XIXe siècle, lorsque l’Italie libérale entreprend l’occupation de la corne de l’Afrique, en Érythrée puis en Somalie, la colonisation trouve quelques échos dans les romans de Salgari. On trouve aussi des textes qui célèbrent l’héroïsme des soldats tombés au combat en affrontant des indigènes barbares et cruels, et d’autres qui critiquent la politique coloniale de l’État. Au début du XXe siècle, les ambitions coloniales semblent avoir été mises entre parenthèses ; des romans africains d’aventures, écrits sur le mode de la parodie, tournent en ridicule les Africains pour faire rire les plus petits. Ensuite la guerre de Libye (1911-1912 marque un tournant, et dans les ouvrages publiés au moment de la campagne perce la nouvelle idéologie nationaliste. Après la Grande Guerre, le fascisme au pouvoir veut créer la « conscience coloniale » des Italiens, en y associant la littérature pour l’enfance. Lors de la guerre d’Éthiopie paraissent de nombreux contes et romans qui racontent la campagne militaire sous diverses formes fictionnelles, allant du conte au roman. Cette production présentera la conquête éthiopienne comme une aventure enthousiasmante pour les enfants italiens, et la colonisation comme un immense bienfait pour les enfants indigènes.

Emi la Fafa / Mon Père et moi. Récit autobiographique de Joseph ...

African Journals Online (AJOL)

L'homme semble transférer tout son amour à sur son fils et aussi sur sa concubine préférée seulement parce qu'elle se consacre à l'enfant. Il travaille avec une application soutenue à l'éducation et au bien-être de son fils. Le fils finit par réaliser la sincérité et l'ardeur de l'amour de son père et lui rend de tout coeur son ...

Analysis of Transmedia Storytelling in Pokémon GO

OpenAIRE

Iva Nedelcheva

2016-01-01

This study is part of a doctoral thesis on the topic of Hyperfiction: Past, Present and Future of Storytelling through Hypertext. It explores in depth the impact of transmedia storytelling and the role of hypertext in the realm of the currently popular social media phenomenon Pokémon GO. Storytelling is a powerful method to engage and unite people. Moreover, the technology progress adds a whole new angle to the method, with hypertext and cross-platform sharing that enhance the traditional sto...

V899 MON: AN OUTBURSTING PROTOSTAR WITH A PECULIAR LIGHT CURVE, AND ITS TRANSITION PHASES

Energy Technology Data Exchange (ETDEWEB)

Ninan, J. P.; Ojha, D. K.; Baug, T. [Department of Astronomy and Astrophysics, Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai 400 005 (India); Bhatt, B. C.; Anupama, G. C. [Indian Institute of Astrophysics, Korama ngala, Bangalore 560 034 (India); Mohan, V. [Inter-University Centre for Astronomy and Astrophysics, Pune 411 007 (India); Ghosh, S. K. [National Centre for Radio Astrophysics, Tata Institute of Fundamental Research, Pune 411 007 (India); Men’shchikov, A. [Laboratoire AIM, CEA/DSM-CNRS-Université Paris Diderot, IRFU/SAp, CEA Saclay, Orme des Merisiers, F-91191 Gif-sur-Yvette (France); Tamura, M. [National Astronomical Observatory of Japan, Mitaka, Tokyo 181-8588 (Japan); Henning, Th., E-mail: ninan@tifr.res.in [Max-Planck-Institute for Astronomy, Königstuhl 17, D-69117 Heidelberg (Germany)

2015-12-10

We present a detailed study of V899 Mon (a new member in the FUors/EXors family of young low-mass stars undergoing outburst), based on our long-term monitoring of the source starting from 2009 November to 2015 April. Our optical and near-infrared photometric and spectroscopic monitoring recorded the source transitioning from its first outburst to a short-duration quiescence phase (<1 yr), and then returning to a second outburst. We report here the evolution of the outflows from the inner region of the disk as the accretion rate evolved in various epochs. Our high-resolution (R ∼ 37,000) optical spectrum could resolve interesting clumpy structures in the outflow traced by various lines. Change in far-infrared flux was also detected between two outburst epochs. Based on our observations, we constrained various stellar and envelope parameters of V899 Mon, as well as the kinematics of its accretion and outflow. The photometric and spectroscopic properties of this source fall between classical FUors and EXors. Our investigation of V899 Mon hints at instability associated with magnetospheric accretion being the physical cause of the sudden short-duration pause of the outburst in 2011. It is also a good candidate to explain similar short-duration pauses in outbursts of some other FUors/EXors sources.

The Contribution of Women's Writing to the Literature and Intellectual Achievements of the Caribbean: "Moi, Tituba Sorciere" and "Amour, Colere et Folie."

Science.gov (United States)

Araujo, Nara

1994-01-01

Explores literary universe of Caribbean women writers, discusses contributions as reflective of their self-image, and examines Caribbean literature as collective identity of region. Author explains use of writing as means of linking events that reveal experiences of Caribbean women through more detailed analysis of two novels: "Moi, Tituba…

Composition of forage and grain from second-generation insect-protected corn MON 89034 is equivalent to that of conventional corn (Zea mays L.).

Science.gov (United States)

Drury, Suzanne M; Reynolds, Tracey L; Ridley, William P; Bogdanova, Natalia; Riordan, Susan; Nemeth, Margaret A; Sorbet, Roy; Trujillo, William A; Breeze, Matthew L

2008-06-25

Insect-protected corn hybrids containing Cry insecticidal proteins derived from Bacillus thuringiensis have protection from target pests and provide effective management of insect resistance. MON 89034 hybrids have been developed that produce both the Cry1A.105 and Cry2Ab2 proteins, which provide two independent modes of insecticidal action against the European corn borer ( Ostrinia nubilalis ) and other lepidopteran insect pests of corn. The composition of MON 89034 corn was compared to conventional corn by measuring proximates, fiber, and minerals in forage and by measuring proximates, fiber, amino acids, fatty acids, vitamins, minerals, antinutrients, and secondary metabolites in grain collected from 10 replicated field sites across the United States and Argentina during the 2004-2005 growing seasons. Analyses established that the forage and grain from MON 89034 are compositionally comparable to the control corn hybrid and conventional corn reference hybrids. These findings support the conclusion that MON 89034 is compositionally equivalent to conventional corn hybrids.

VLBI detection of the internal shocks in nova V959 Mon

Science.gov (United States)

Yang, J.; Paragi, Z.; O'Brien, T.; Chomiuk, L.; Linford, J. D.

V959 Mon is a classical nova detected at GeV gamma-ray wavelengths on 2012 June 19. While classical novae are now routinely detected in gamma-rays, the origin of the shocks that produce relativistic particles has remained unknown. We carried out electronic European VLBI Network (e-EVN) observations that revealed a pair of compact synchrotron emission features in V959 Mon on 2012 Sep 18. Since synchrotron emission requires strong shocks as well, we identify these features as the location where the gamma rays were produced. We also detected the extended ejecta in the follow-up EVN observations. They expanded much faster in East-West direction than the compact knots detected in the aforementioned e-EVN measurements. By comparing the VLBI results with lower resolution images obtained using e-MERLIN and the VLA - as reported by Chomiuk et al. (2014) - it appears that 1) influenced by the binary orbit, the nova ejecta was highly asymmetric with a dense and slow outflow in the equatorial plane and low-density and faster ejecta along the poles; and 2) the VLBI knots were related to shocks formed in the interaction region of these outflows.

Development, survival and fitness performance of Helicoverpa zea (Lepidoptera: Noctuidae) in MON810 Bt field corn.

Science.gov (United States)

Horner, T A; Dively, G P; Herbert, D A

2003-06-01

Helicoverpa zea (Boddie) development, survival, and feeding injury in MON810 transgenic ears of field corn (Zea mays L.) expressing Bacillus thuringiensis variety kurstaki (Bt) Cry1Ab endotoxins were compared with non-Bt ears at four geographic locations over two growing seasons. Expression of Cry1Ab endotoxin resulted in overall reductions in the percentage of damaged ears by 33% and in the amount of kernels consumed by 60%. Bt-induced effects varied significantly among locations, partly because of the overall level and timing of H. zea infestations, condition of silk tissue at the time of egg hatch, and the possible effects of plant stress. Larvae feeding on Bt ears produced scattered, discontinuous patches of partially consumed kernels, which were arranged more linearly than the compact feeding patterns in non-Bt ears. The feeding patterns suggest that larvae in Bt ears are moving about sampling kernels more frequently than larvae in non-Bt ears. Because not all kernels express the same level of endotoxin, the spatial heterogeneity of toxin distribution within Bt ears may provide an opportunity for development of behavioral responses in H. zea to avoid toxin. MON810 corn suppressed the establishment and development of H. zea to late instars by at least 75%. This level of control is considered a moderate dose, which may increase the risk of resistance development in areas where MON810 corn is widely adopted and H. zea overwinters successfully. Sublethal effects of MON810 corn resulted in prolonged larval and prepupal development, smaller pupae, and reduced fecundity of H. zea. The moderate dose effects and the spatial heterogeneity of toxin distribution among kernels could increase the additive genetic variance for both physiological and behavioral resistance in H. zea populations. Implications of localized population suppression are discussed.

All Electron ab initio Investigations of the Electronic States of the MoN Molecule

DEFF Research Database (Denmark)

Shim, Irene; Gingerich, Karl A.

1999-01-01

The low lying electronic states of the molecule MoN have been investigated by performing all electron ab initio multi-configuration self-consistent-field (CASSCF) calculations. The relativistic corrections for the one electron Darwin contact term and the relativistic mass-velocity correction have...

Intraguild competition and enhanced survival of western bean cutworm (Lepidoptera: Noctuidae) on transgenic Cry1Ab (MON810) Bacillus thuringiensis corn.

Science.gov (United States)

Dorhout, David L; Rice, Marlin E

2010-02-01

The effect of genetically modified corn (event MON810, YieldGard Corn Borer) expressing the Bacillus thuringiensis sp. kurstaki (Berliner) (Bt) endotoxin, Cry1Ab, on the survival of western bean cutworm, Striacosta albicosta (Smith), larvae was examined during intraguild competition studies with either European corn borer, Ostrinia nubilalis (Hübner), or corn earworm, Helicoverpa zea (Boddie), larvae. Competition scenarios were constructed by using either a laboratory or field competition arena containing one of five different diets and one of 13 different larval size-by-species scenarios. The survival of western bean cutworms competing with corn earworms in the laboratory arenas on either a meridic diet or isoline corn silk diet was significantly lower (P corn earworm on a Cry1Ab-MON810 corn silk diet was significant higher (P corn borers generally did not alter the outcomes observed in the western bean cutworm and corn earworm only two-way competitions. These data suggest that Cry1Ab-MON810 corn may confer a competitive advantage to western bean cutworm larvae during intraguild competition, particularly from corn earworms, and that western bean cutworms become equal competitors only when they are of equal or larger size and the diet is Cry1Ab-MON810 corn.

Stratigraphy and Observations of Nepthys Mons Quadrangle (V54), Venus

Science.gov (United States)

Bridges, N. T.

2001-01-01

Initial mapping has begun in Venus' Nepthys Mons Quadrangle (V54, 300-330 deg. E, 25-50 deg. S). Major research areas addressed are how the styles of volcanism and tectonism have changed with time, the evolution of shield volcanoes, the evolution of coronae, the characteristics of plains volcanism, and what these observations tell us about the general geologic history of Venus. Reported here is a preliminary general stratigraphy and several intriguing findings. Additional information is contained in the original extended abstract.

Monólogos humorísticos televisivos en la clase de español como lengua extranjera: Herramientas de aprendizaje

Directory of Open Access Journals (Sweden)

Fermín Martos Eliche

2015-01-01

Full Text Available El estudio que presentamos pretende añadir una visión interdisciplinar del uso de un tipo de discurso muy extendido en nuestra sociedad que ejemplifica muy adecuadamente la llamada inteligencia cultural: el monólogo. Se trata de acercar al estudiante de español de niveles avanzados a elementos subyacentes - difícilmente explicables- de los diferentes niveles lingüísticos y culturales del español a través de los monólogos humorísticos que aparecen en televisión. Analizamos la importancia del humor y de la inteligencia cultural en estos monólogos, haciendo hincapié en lo que llamamos minimonólogos y su utilidad en la enseñanza del español como lengua extranjera, pues en ellos confluyen los más diversos elementos culturales de la lengua, lo que permite al estudiante acercarse a la realidad a la vez que se divierte durante el proceso educativo.

NO/sub x/ removal facility: MON process

Energy Technology Data Exchange (ETDEWEB)

Fukuda, Y

1974-05-01

A newly developed process for nitrogen oxides removal is described. The MON process, named for Mitsubishi Kizoku, Okabe of Tohoku Univ., and Nippon Kagaku, uses potassium permanganate as an oxidizing agent. Potassium permanganate in alkaline solution converts nitric oxide into nitrate and nitrogen dioxide into nitric acid. The resulting MnO/sub 2/ is easily filtered and recovered as material for the manufacturing of KMnO/sub 4/. Contrary to the conventional methods, the NO/sub x/ conversion rate increases with increasing temperature. Test results at a pilot plant showed that NO/sub x/ was reduced from 570 ppM (nitric oxide 520 ppM) to 27 ppM (mostly NO) at 97 to 98 percent conversion. Another advantage of the process is that other acidic gases such as sulfur dioxide are also removed.

Development and reproduction of Spodoptera eridania (Lepidoptera: Noctuidae) and its egg parasitoid Telenomus remus (Hymenoptera: Platygastridae) on the genetically modified soybean (Bt) MON 87701×MON 89788.

Science.gov (United States)

Bortolotto, O C; Silva, G V; de Freitas Bueno, A; Pomari, A F; Martinelli, S; Head, G P; Carvalho, R A; Barbosa, G C

2014-12-01

Genetically modified crops with insect resistance genes from Bacillus thuringiensis Berliner (Bt-plants) are increasingly being cultivated worldwide. Therefore, it is critical to improve our knowledge of their direct or indirect impact not only on target pests but also on non-target arthropods. Hence, this study evaluates comparative leaf consumption and performance of Spodoptera eridania (Cramer), a species that is tolerant of the Cry1Ac protein, fed with Bt soybean, MON 87701×MON 89788 or its near [corrected] non-Bt isoline. Using this species as a model, we assessed [corrected] the comparative performance of the egg parasitoid Telenomus remus Nixon on eggs of S. eridania produced from individuals that fed on these two soybean genotypes [corrected] as larvae. Results showed that Bt soybean did not affect pest foliage consumption, but did reduce larvel duration by two days despite larvae in both treatments having six instars. Nevertheless, survival of S. eridania larvae, pupal weight, sex ratio, fecundity and longevity of female moths, and egg viability did not differ between Bt and non-Bt soybeans. Adult longevity of S. eridania males was increased when caterpillars were fed with Bt soybean versus the near isoline. No adverse effects of this technology were observed for the egg parasitoid T. remus. [corrected].

La voix off au féminin : Hiroshima mon amour et Aurélia Steiner

Directory of Open Access Journals (Sweden)

Jennifer Cazenave

2011-07-01

Full Text Available Une étude comparée du grand film moderne d’Alain Resnais, Hiroshima mon amour (1959, et du dyptique de Marguerite Duras, Aurélia Steiner (1979, laisse entrevoir une filiation entre deux films que vingt ans séparent et où s’entrecroisent un certain nombre de fils conducteurs : le lieu et la parole ; l’histoire et la mémoire ; la voix-off au féminin et l’irreprésentable. Il s’agira donc de penser ces deux œuvres cinématographiques à partir du rapport entre le parler féminin et la représentation du passé, soit la tonte des femmes au moment de la libération dans Hiroshima mon amour, soit l’extermination des Juifs d’Europe dans Aurélia Steiner.

Loss of residual monomer from resilient lining materials processed by different methods = Perda de monômero residual de reembasadores resilientes processados por diferentes métodos

Directory of Open Access Journals (Sweden)

León, Blanca Liliana Torres

2008-01-01

Full Text Available Objetivo: Avaliar o monômero residual liberado de materiais resilientes para reembasamento polimerizados por diferentes métodos. Metodologia: Dois materiais foram testados: Ever-Soft polymerizado por banho quente de água ou por energia de microondas, e Light Liner polimerizado quimicamente e por luz visível (polimerização dual. O monômero residual liberado foi mensurado em 12 espécimes (40x10x0,3mm fabricados com cada material e método de polimerização. Os espécimes foram armazenados em água destilada por 168 horas a 37ºC, e analisados diariamente por espectrometria ultravioleta (Light Liner: 204nm, Ever-Soft: 206nm. Os dados foram analisados por ANOVA de fator único e teste de Bonferroni (a=0,05. O monômero residual liberado em relação ao tempo foi determinado por análise de regressão polinomial. Resultados: O monômero residual liberado em 168 horas do teste (µg/cm2 em espécimes polimerizados por banho de água quente (0,27±0,01µg/cm2 foi significativamente maior (P < 0,05 que em espécimes processados por energia de microondas (0,25±0,02µg/cm2. Ever-Soft mostrou uma redução na liberação de monomer residual com o tempo, tendendo a se estabilizar em 96 horas. Light Liner continuou a liberar monômero com o tempo. Conclusão: Ever-Soft pode ser polimerizado por energia de microondas. Os valores de monômero residual liberado foram baixos, e os níveis de monômero diminuíram com o tempo

Origin of Sinuous Channels on the SW Apron of Ascraeus Mons and the Surrounding Plains, Mars

Science.gov (United States)

Schierl, Z. P.; Spencer, P.; Signorella, J.; Collins, A.; Schwans, B.; de Wet, A. P.; Bleacher, J. E.

2012-03-01

We used a variety of spacecraft imagery to determine the most likely origin for a network of sinuous channels found on the southwest apron of Ascraeus Mons and that extend out onto the surrounding plains.

Agronomic performance of insect-protected and herbicide-tolerant MON 89034 × TC1507 × NK603 × DAS-40278-9 corn is equivalent to that of conventional corn.

Science.gov (United States)

de Cerqueira, Denise T Rezende; Schafer, Ariane C; Fast, Brandon J; Herman, Rod A

2017-07-03

Agronomic characteristics of genetically modified (GM) MON 89034 × TC1507 × NK603 × DAS-40278-9 (PowerCore™ Enlist™), MON 89034 × TC1507 × NK603 (PowerCore™), and DAS-40278-9 (Enlist™) corn, a non-GM near-isogenic hybrid, and 2 commercial non-GM hybrids were assessed in a field study to determine if the agronomic performance of the GM corn hybrids is equivalent to that of non-transgenic hybrid corn. The MON 89034 × TC1507 × NK603 × DAS-40278-9 hybrid corn was developed through stacking of 4 individual transgenic events, MON 89034, TC1507, NK603, and DAS-40278-9 by traditional breeding and contains the cry1A.105 and cry2Ab2 (MON 89034), cry1F and pat (TC1507), cp4 epsps (NK603) and aad-1 (DAS-40278-9) transgenes. These transgenes encode the proteins Cry1A.105, Cry2Ab2, and Cry1F, which confer insect resistance, PAT, CP4 EPSPS, and AAD-1, which confer herbicide tolerance. The following agronomic characteristics were assessed in the study: initial and final stand count, seedling vigor, time to silk, time to pollen shed, pollen viability, plant height, ear height, stalk lodging, root lodging, days to maturity, stay green, disease incidence, insect damage, herbicide injury, and yield. The agronomic assessment was conducted in 2 regions of Brazil (Indianopolis-MG; Cravinhos-SP). The agronomic attributes for all GM entries were statistically indistinguishable from the non-GM near-isogenic hybrid. In addition, most of the agronomic assessments fell within the range of the commercial varieties included in the study. Taken together, MON 89034 × TC1507 × NK603 × DAS-40278, MON 89034 × TC1507 × NK603, and DAS-40278-9 were found to be agronomically equivalent to non-GM corn.

Between Freedom and Constraint: ROM Hacking of Pokémon Games

OpenAIRE

Barnabé, Fanny

2018-01-01

This paper aims to study a creative practice widespread in video game cultures: “ROM hacking”. By examining with the tools of rhetoric a defined corpus of ROM hacks derived from 『Pokémon』 games, the presentation will show that the formal construction of these derivative works demonstrates less a free or subversive transformation than a fairly strict respect for the original games’ conventions. By reproducing the structure of official 『Pokémon 』games, these fan productions become mirrors revea...

Geology of the Tyrrhenus Mons Lava Flow Field, Mars

Science.gov (United States)

Crown, David A.; Mest, Scott C.

2014-11-01

The ancient, eroded Martian volcano Tyrrhenus Mons exhibits a central caldera complex, layered flank deposits dissected by radial valleys, and a 1000+ km-long flow field extending to the southwest toward Hellas Planitia. Past studies suggested an early phase of volcanism dominated by large explosive eruptions followed by subsequent effusive activity at the summit and to the southwest. As part of a new geologic mapping study of northeast Hellas, we are examining the volcanic landforms and geologic evolution of the Tyrrhenus Mons flow field, including the timing and nature of fluvial activity and effects on volcanic units. New digital geologic mapping incorporates THEMIS IR (100 m/pixel) and CTX (5 m/pixel) images as well as constraints from MOLA topography.Mapping results to-date include delineation of the boundaries of the flow field, identification and mapping of volcanic and erosional channels within the flow field, and mapping and analysis of lava flow lobes. THEMIS IR and CTX images allow improved discrimination of the numerous flow lobes that are observed in the flow field, including refinement of the margins of previously known flows and identification of additional and smaller lobes. A prominent sinuous rille extending from Tyrrhenus Mons’ summit caldera is a major feature that supplied lava to the flow field. Smaller volcanic channels are common throughout the flow field; some occur in segments along crests of local topographic highs and may delineate lava tubes. In addition to volcanic channels, the flow field surface is characterized by several types of erosional channels, including wide troughs with scour marks, elongate sinuous channels, and discontinuous chains of elongate pits and troughs. High-resolution images reveal the widespread and significant effects of fluvial activity in the region, and further mapping studies will examine spatial and temporal interactions between volcanism and fluvial processes.

Motivational Objects in Natural Scenes (MONS: A Database of >800 Objects

Directory of Open Access Journals (Sweden)

Judith Schomaker

2017-09-01

Full Text Available In daily life, we are surrounded by objects with pre-existing motivational associations. However, these are rarely controlled for in experiments with natural stimuli. Research on natural stimuli would therefore benefit from stimuli with well-defined motivational properties; in turn, such stimuli also open new paths in research on motivation. Here we introduce a database of Motivational Objects in Natural Scenes (MONS. The database consists of 107 scenes. Each scene contains 2 to 7 objects placed at approximately equal distance from the scene center. Each scene was photographed creating 3 versions, with one object (“critical object” being replaced to vary the overall motivational value of the scene (appetitive, aversive, and neutral, while maintaining high visual similarity between the three versions. Ratings on motivation, valence, arousal and recognizability were obtained using internet-based questionnaires. Since the main objective was to provide stimuli of well-defined motivational value, three motivation scales were used: (1 Desire to own the object; (2 Approach/Avoid; (3 Desire to interact with the object. Three sets of ratings were obtained in independent sets of observers: for all 805 objects presented on a neutral background, for 321 critical objects presented in their scene context, and for the entire scenes. On the basis of the motivational ratings, objects were subdivided into aversive, neutral, and appetitive categories. The MONS database will provide a standardized basis for future studies on motivational value under realistic conditions.

Motivational Objects in Natural Scenes (MONS): A Database of >800 Objects.

Science.gov (United States)

Schomaker, Judith; Rau, Elias M; Einhäuser, Wolfgang; Wittmann, Bianca C

2017-01-01

In daily life, we are surrounded by objects with pre-existing motivational associations. However, these are rarely controlled for in experiments with natural stimuli. Research on natural stimuli would therefore benefit from stimuli with well-defined motivational properties; in turn, such stimuli also open new paths in research on motivation. Here we introduce a database of Motivational Objects in Natural Scenes (MONS). The database consists of 107 scenes. Each scene contains 2 to 7 objects placed at approximately equal distance from the scene center. Each scene was photographed creating 3 versions, with one object ("critical object") being replaced to vary the overall motivational value of the scene (appetitive, aversive, and neutral), while maintaining high visual similarity between the three versions. Ratings on motivation, valence, arousal and recognizability were obtained using internet-based questionnaires. Since the main objective was to provide stimuli of well-defined motivational value, three motivation scales were used: (1) Desire to own the object; (2) Approach/Avoid; (3) Desire to interact with the object. Three sets of ratings were obtained in independent sets of observers: for all 805 objects presented on a neutral background, for 321 critical objects presented in their scene context, and for the entire scenes. On the basis of the motivational ratings, objects were subdivided into aversive, neutral, and appetitive categories. The MONS database will provide a standardized basis for future studies on motivational value under realistic conditions.

Characterization of the ecological interactions of Roundup Ready 2 Yield® soybean, MON 89788, for use in ecological risk assessment.

Science.gov (United States)

Horak, Michael J; Rosenbaum, Eric W; Phillips, Samuel L; Kendrick, Daniel L; Carson, David; Clark, Pete L; Nickson, Thomas E

2015-01-01

As part of an ecological risk assessment, Roundup Ready 2 Yield® soybean (MON 89788) was compared to a conventional control soybean variety, A3244, for disease and arthropod damage, plant response to abiotic stress and cold, effects on succeeding plant growth (allelopathic effects), plant response to a bacterial symbiont, and effects on the ability of seed to survive and volunteer in a subsequent growing season. Statistically significant differences between MON 89788 and A3244 were considered in the context of the genetic variation known to occur in soybean and were assessed for their potential impact on plant pest (weed) potential and adverse environmental impact. The results of these studies revealed no effects of the genetic modification that would result in increased pest potential or adverse environmental impact of MON 89788 compared with A3244. This paper illustrates how such characterization studies conducted in a range of environments where the crop is grown are used in an ecological risk assessment of the genetically modified (GM) crop. Furthermore, risk assessors and decision makers use this information when deciding whether to approve a GM crop for cultivation in-or grain import into-their country.

Pokémon Go: Ubiquitous Computing Delivering Better Health or Co-Incidental Health Benefits from Technology Use? A Participatory Observational Study.

Science.gov (United States)

Yee, Kwang Chien; Wong, Ming Chao; Turner, Paul

2017-01-01

Stimulating sustained behavioural change through information and technology has been an aim of much health informatics research. Traditional approaches use technology to mediate communications between health professionals and patients. More recent lifestyle technologies engage the patient directly with information and advice - but what of the phenomena that is Pokémon Go - does it point to another way of achieving health benefits through fun? This paper aims to explore some of the conceptual questions for health informatics stimulated by the phenomenal popularity of Pokémon Go. The paper is grounded analysis of data generated through a preliminary participatory observational study in Australia.

L’alternative monétaire Bitcoin : une perspective institutionnaliste

OpenAIRE

Lakomski-Laguerre, Odile; Desmedt, Ludovic

2015-01-01

Depuis quelques années, nous assistons à l’émergence de monnaies d’un genre nouveau, reposant sur des procédés cryptographiques, gérées en pair à pair selon un consensus distribué. La plus représentative d’entre elles, le Bitcoin, est lancée après la crise financière de 2008 et vient contester un ordre monétaire fondé sur le crédit et le pouvoir bancaire. Ces crypto-monnaies viennent heurter la conception traditionnelle de la monnaie : unitaire, souveraine, territoriale et centralisée. Par co...

Aproximações à medicina monástica em Portugal na Idade Média

Directory of Open Access Journals (Sweden)

Dulce O. Amarante dos Santos

2012-06-01

Full Text Available Este texto investiga os indícios da existência de uma medicina monástica no reino de Portugal na Idade Média, antes e depois da fundação da Universidade em 1290, realizada por D. Dinis. O corpus de fontes analisado inclui regras beneditinas e agostinianas, costumeiros ou liber ordinis, catálogo das livrarias de mão do mosteiro de Santa Cruz de Coimbra, legislação conciliar. Assinala dois momentos basilares nessa história, sendo o primeiro a criação da regra beneditina no IV século, que resultou na criação de dois espaços próprios para o exercício da medicina monástica associados à prática da virtude da caridade: a enfermaria e o hospital. O segundo momento, no século XIII, constitui-se na institucionalização da escolástica médica e, ao mesmo tempo, nas tentativas de coibir a prática médica pelos religiosos nos sínodos regionais e no IV Concílio de Latrão (1215.

Ryšių su klientais valdymas nekilnojamojo turto sektoriaus įmonėse: privalumų ir ribojančių veiksnių tyrimas

OpenAIRE

Tvaronavičius, Vytautas; Bruzgė, Šarūnas; Mačiulis, Alminas

2008-01-01

Globalizacija, intensyvi konkurencija ir kintanti vartotojų paklausa skatina įmones ieškoti būdų, leidžiančių joms išlikti konkurencingomis rinkoje. Todėl ryšių su klientais valdymas tampa aktualus šiandienos verslo įmonėms. Straipsnyje analizuojami ryšių su klientais valdymo diegimo privalumai ir ribojantys veiksniai nekilnojamojo turto sektoriaus įmonėse. Straipsnio pabaigoje pateikiami apibendrinti tyrimo rezultatai ir išvados.

Vessels of Transfer: Allegories of Afrofuturism in Jeff Mills and Janelle Monáe

Directory of Open Access Journals (Sweden)

tobias c. van Veen

2013-11-01

Full Text Available 0 0 1 228 1304 bacon 10 3 1529 14.0 Normal 0 false false false EN-US JA X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman";} The performances, music, and subjectivities of Detroit techno producer Jeff Mills—radio turntablist The Wizard, space-and-time traveller The Messenger, founding member of Detroit techno outfit Underground Resistance and head of AXIS Records—and Janelle Monáe—android #57821, Cindi Mayweather, denizen and “cyber slavegirl” of Metropolis—are infused with the black Atlantic imaginary of Afrofuturism. We might understand Mills and Monáe as disseminating, in the words of Paul Gilroy, an Afrofuturist “cultural broadcast” that feeds “a new metaphysics of blackness” enacted “within the underground, alternative, public spaces constituted around an expressive culture . . . dominated by music” (Gilroy 1993: 83. Yet what precisely is meant by “blackness”—the black Atlantic of Gilroy’s Afrodiasporic cultural network—in a context that is Afrofuturist? Monáe’s Cindi Mayweather is an android on the run from human authorities, and Mills has become The Messenger, a time-and-space traveller returning from the future to forewarn Earth of catastrophic first contact with extraterrestials. The repetitious signature of electronic music, through its sonic affect, likewise appears to amplify nonrepresentational strategies. At stake is the role of allegory and its infrastructure: does Afrofuturism, and its incarnates, “represent” blackness? Or does it tend toward an unhinging of allegory, in which the coordinates of blackness, but also those of linear temporality and terrestial subjectivity

QUANTIFICATION OF GENETICALLY MODIFIED MAIZE MON 810 IN PROCESSED FOODS

Directory of Open Access Journals (Sweden)

Peter Siekel

2012-12-01

Full Text Available 800x600 Normal 0 21 false false false SK X-NONE X-NONE MicrosoftInternetExplorer4 Maize MON 810 (Zea mays L. represents the majority of genetically modified food crops. It is the only transgenic cultivar grown in the EU (European Union countries and food products with its content higher than 0.9 % must be labelled. This study was aimed at impact of food processing (temperature, pH and pressure on DNA degradation and quantification of the genetically modified maize MON 810. The transgenic DNA was quantified by the real-time polymerase chain reaction method. Processing as is high temperature (121 °C, elevated pressure (0.1 MPa and low pH 2.25 fragmented DNA. A consequence of two order difference in the species specific gene content compared to the transgenic DNA content in plant materials used has led to false negative results in the quantification of transgenic DNA. The maize containing 4.2 % of the transgene after processing appeared to be as low as 3.0 % (100 °C and 1.9 % (121 °C, 0.1 MPa. The 2.1 % amount of transgene dropped at 100 °C to 1.0 % and at 121 °C, 0.1 MPa to 0.6 %. Under such make up the DNA degradation of transgenic content showed up 2 or 3 time higher decrease a consequence of unequal gene presence. Such genes disparity is expressed as considerable decrease of transgenic content while the decrease of species specific gene content remains unnoticed. Based on our findings we conclude that high degree of processing might have led to false negative results of the transgenic constituent quantification. Determination of GMO content in processed foods may leads to incorrect statement and labelling in these cases could misleads consumers.doi:10.5219/212

Diffusion barrier performances of thin Mo, Mo-N and Mo/Mo-N films between Cu and Si

International Nuclear Information System (INIS)

Song Shuangxi; Liu Yuzhang; Mao Dali; Ling Huiqin; Li Ming

2005-01-01

In this work, we have studied the diffusion barrier performances of Mo, Mo-N and Mo/Mo-N metallization layers deposited by sputtering Mo in Ar/N 2 atmospheres, respectively. Samples were subsequently annealed at different temperatures ranging from 400 to 800 deg C in vacuum condition. The film properties and their suitability as diffusion barriers and protective coatings in silicon devices were characterized using four-point probe measurement, X-ray diffractometry, scanning electron microscopy, Auger electron spectroscopy and transmission electron microscopy analyses. Experimental results revealed that the Mo (20 nm)/Mo-N (30 nm) layer was able to prevent the diffusion reaction between Cu and Si substrate after being annealed at 600 deg C for 30 min. The adhesion between layers and the content of N atoms are the key parameters to improve the properties of Mo-based barrier materials. The Mo layer interposed between Cu and Mo-N diluted the high nitrogen concentration of the barrier and so enhanced the barrier performances

Uranium-phosphate relationship in phosphated chalks of the Mons and Picardie Bassins

Energy Technology Data Exchange (ETDEWEB)

Quinif, Y; Charlet, J M; Dupuis, C; Robaszynski, F [Faculte Polytechnique de Mons (Belgium)

1981-11-30

The lithological and geochemical conditions relative to the ''Senonian'' phosphatic chalks are relatively simple in the Basins of Mons (Belgium) and of Picardy (France). Their characteristics permit us to study chiefly the uranium-phosphate relation. It appears a very good linear correlation between the phosphate and the uranium. The coefficient U/P/sub 2/O/sub 5/ remains a constant from the bottom to the top of the same section, but changes in space for synchronic formations (lateral variation of geochemical facies) and in time for two separated basins.

Formation, properties, and ion irradiation effects of hexagonal structure MoN thin films

International Nuclear Information System (INIS)

Christen, D.K.; Sekula, S.T.; Ellis, J.T.; Lewis, J.D.; Williams, J.M.

1986-09-01

Thin films (100-120 nm) of hexagonal structures MoN have been fabricated by reaction of Mo films in an NH 3 atmosphere. The as-formed films possessed superconducting transition temperatures T/sub c/ ≅ 13 0 K, with resistance ratios r = R(296K)/R(T/sub c/) in the range 5 to 10, low-temperature normal state resistivities rho 0 = 4 to 10 μΩ-cm, and extrapolated upper critical fields H/sub c2/(0) = 4.0 to 5.0 T. Thin film x-ray diffraction patterns revealed no visible second phase, with measured lattice parameters close to literature values. The effects of lattice disorder on the superconducting and electronic properties were investigated by irradiation with nitrogen ions of energy 45 and 340 keV, resulting in a nearly uniform damage profile without the introduction of any new chemical species. The results indicate that ordered hexagonal MoN shows some of the unusual properties characteristic of moderate-to-high T/sub c/ transition metal compounds, but is relatively insensitive to degradation of the superconducting properties by lattice disorder. For ion fluences PHI up to 2 x 10 16 N-ions/cm 2 , T/sub c/ is found to decrease monotonically and saturate at 9.5 0 K, almost 3/4 the initial value, while H/sub c2/(0) undergoes a gradual increase to 11T

Comparison of the forage and grain composition from insect-protected and glyphosate-tolerant MON 88017 corn to conventional corn (Zea mays L.).

Science.gov (United States)

McCann, Melinda C; Trujillo, William A; Riordan, Susan G; Sorbet, Roy; Bogdanova, Natalia N; Sidhu, Ravinder S

2007-05-16

The next generation of biotechnology-derived products with the combined benefit of herbicide tolerance and insect protection (MON 88017) was developed to withstand feeding damage caused by the coleopteran pest corn rootworm and over-the-top applications of glyphosate, the active ingredient in Roundup herbicides. As a part of a larger safety and characterization assessment, MON 88017 was grown under field conditions at geographically diverse locations within the United States and Argentina during the 2002 and 2003-2004 field seasons, respectively, along with a near-isogenic control and other conventional corn hybrids for compositional assessment. Field trials were conducted using a randomized complete block design with three replication blocks at each site. Corn forage samples were harvested at the late dough/early dent stage, ground, and analyzed for the concentration of proximate constituents, fibers, and minerals. Samples of mature grain were harvested, ground, and analyzed for the concentration of proximate constituents, fiber, minerals, amino acids, fatty acids, vitamins, antinutrients, and secondary metabolites. The results showed that the forage and grain from MON 88017 are compositionally equivalent to forage and grain from control and conventional corn hybrids.

Monitoring of Sesamia nonagrioides resistance to MON 810 maize in the European Union: lessons from a long-term harmonized plan.

Science.gov (United States)

Farinós, Gema P; Hernández-Crespo, Pedro; Ortego, Félix; Castañera, Pedro

2018-03-01

Use of MON 810 maize (Zea mays), which expresses the insecticidal protein Cry1Ab from Bacillus thuringiensis (Bt maize), is a highly effective method to control Sesamia nonagrioides (Lefèbvre), a key maize pest in Mediterranean countries. Monitoring programs to assess the potential development of resistance of target pests to Bt maize are mandatory in the European Union (EU). Here we report the results of the S. nonagrioides resistance monitoring plan implemented for MON 810 maize in the EU between 2004 and 2015 and reassess the different components of this long-term harmonized plan. No major shifts in the susceptibility of S. nonagrioides to the Cry1Ab protein have occurred over time. The reassessment of this long-term program has identified some practical and technical constraints, allowing us to provide specific recommendations for improvement: use reference strains instead of susceptibility baselines as comparators for field-collected populations; shift from dose-response bioassays to diagnostic concentrations; and focus monitoring on areas with high adoption rates, such as the Ebro basin in Spain. There are no signs of field resistance of S. nonagrioides to the Cry1Ab protein of MON 810 maize. Specific recommendations for improvement are provided, based on the knowledge and experience accumulated through the implementation of this unique EU-wide harmonized plan. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

Silvio Gesell, socialiste proudhonien et réformateur monétaire

OpenAIRE

Blanc , Jérôme

2001-01-01

National audience; Œuvre postérieure à Proudhon mais reliée à lui, la proposition d'une économie franche et plus spécifiquement d'une monnaie franche par Silvio Gesell, auteur allemand venu sur le tard à l'économie, socialiste proudhonien, décrit par beaucoup comme une sorte de prophète, a jusqu'ici, mais en partie seulement, échappé au destin peu enviable de la plupart des propositions de réforme monétaire qualifiées d'utopiques. Après avoir survolé la vie et l'œuvre de Silvio Gesell, on s'i...

Volcanic or Fluvial Channels on Ascraeus Mons: Focus on the Source Area of Sinuous Channels on the Southeast Rift Apron

Science.gov (United States)

Signorella, J. D.; de Wet, A. P.; Bleacher, J. E.; Collins, A.; Schierl, Z. P.; Schwans, B.

2012-03-01

This study focuses on the source area of sinuous channels on the southeast rift apron on Ascraeus Mons, Mars and attempts to understand whether the channels were formed through volcanic or fluvial processes.

Literature, cinema and history in "Hiroshima Mon Amour"

Directory of Open Access Journals (Sweden)

Nismária Alves David Barros

2013-06-01

Full Text Available This article analyzes Hiroshima Mon Amour, realization by Alain Resnais divulged in 1959 and ciné-roman by Marguerite Duras published in 1960. Considering the Jeanne-Marie Clerc's theory (2004, we understand that the literature and the cinema are resources of expression that do not establish competition or subordination relations, but they establish complementary relations, they make mutual exchanges for their renewals. They are not the documents on the atomic tragedy of Hiroshima because they congregate historical facts, literary narrative and cinematographic techniques. This ciné-roman and this film displays a revolutionary position of the artistic form to express a critical vision on the world after war. They create a love history and a history of loss, focusing the individual anguish in the plot. Through  the return to the past, using a poetical language, they discloses the pains of the protagonist and the pains of the humanity. Therefore the receiver reflects on himself.

Bistand til risikovurdering (evt. ændringer af konklusioner af tidligere risikovurdering) . Zea mays (MON863; MON863x810). Opdateret rammenotat samt supplerende oplysninger til sagen. Modtaget 28-10-2004, deadline: snarest muligt, svar 01-11-2004

DEFF Research Database (Denmark)

Strandberg, Morten Tune; Damgaard, Christian; Kjellsson, Gøsta

2004-01-01

"Vedr. C/DE/02/09: Om Monsantos svar på Pusztai’s kritik giver anledning til ændring af DMU’s kommentarer til GM-majs MON863. Uanset om effekterne er tilfældige elller ej, er størrelsen af de mulige effekter på rotternes sundhed uden betydning i relation til den økologiske risikovurdering. Dermed...

Composition of grain and forage from insect-protected and herbicide-tolerant corn, MON 89034 × TC1507 × MON 88017 × DAS-59122-7 (SmartStax), is equivalent to that of conventional corn (Zea mays L.).

Science.gov (United States)

Lundry, Denise R; Burns, J Austin; Nemeth, Margaret A; Riordan, Susan G

2013-02-27

Monsanto Company and Dow AgroSciences LLC have developed the combined-trait corn product MON 89034 × TC1507 × MON 88017 × DAS-59122-7 (SmartStax, a registered trademark of Monsanto Technology LLC). The combination of four biotechnology-derived events into a single corn product (stacking) through conventional breeding provides broad protection against lepidopteran and corn rootworm insect pests as well as tolerance to the glyphosate and glufosinate-ammonium herbicide families. The purpose of the work described here was to assess whether the nutrient, antinutrient, and secondary metabolite levels in grain and forage tissues of the combined-trait product are comparable to those in conventional corn. Compositional analyses were conducted on grain and forage from SmartStax, a near-isogenic conventional corn hybrid (XE6001), and 14 conventional reference hybrids, grown at multiple locations across the United States. No statistically significant differences between SmartStax and conventional corn were observed for the 8 components analyzed in forage and for 46 of the 52 components analyzed in grain. The six significant differences observed in grain components (p corn, as previously demonstrated for the single-event products.

Lignée de Soja MON87708 Tolérant Au Dicamba

OpenAIRE

Canada, Publié par la Direction des aliments de Santé

2014-01-01

Santé Canada a avisé Monsanto Canada Inc. qu’il ne s’oppose pas à la vente d’aliments dérivés du soja MON87708 tolérant au Dicamba. Le Ministère a réalisé une évaluation approfondie de cette lignée de soja, conformément aux Lignes directrices sur l’évaluation de l’innocuité des aliments nouveaux. Ces lignes directrices sont fondées sur des principes admis internationalement pour l’établissement de l’innocuité des aliments à caractères nouveaux....

Økologisk risikovurdering af en genmo-dificeret glyfosat-tolerant raps MON 88302 i anmeldelse til godkendelse vedr. import til markedsføring under Forordning 1829/2003/EF

DEFF Research Database (Denmark)

Kjellsson, Gøsta; Sørensen, Jesper Givskov; Damgaard, Christian

2012-01-01

, Bioscience concludes, that accidental dispersal, hybridisation and persistence of the MON 88302-oilseed rape is likely to take place over time. The consequences to the environment are likely to be small. Fur-thermore, there are methods to monitor such dispersal of the GMO-plant into cultivated fields...... and surroundings. Although, not directly an environmental issue, we find that dispersal of the MON 88302 oilseed rape could result in problems for co-existence with non-GMO-cultivation....

Infrared photometry of cataclysmic variables. II - Evidence for ellipsoidal variations in CW MoN, X Leo, IP Peg, and AF CaM

Science.gov (United States)

Szkody, P.; Mateo, M.

1986-08-01

Broadband H or K light curves of the dwarf novae CM Mon, X Leo, IP Peg, and AF Cam reveal variations that can be attributed to ellipsoidal modulation of the secondaries in these systems. The present data imply orbital periods of 4.23 + or - 0.01 hr for CW Mon and 5.0 + or - 0.1 hr for X Leo. The high-amplitude ellipsoidal modulation of the secondary of CW Mon implies a large orbital inclination. The interpretation of the low-amplitude variability seen in X Leo is complicated by details in its light curve and a recent determination of its orbital period by Shafter and Harkness (1986) which differs significantly from the period inferred from the present observations. The light variations of the eclipsing system IP Peg are interpreted as showing a 0.2 mag ellipsoidal variation from the secondary superposed on a deep eclipse of the IR light of the white dwarf and hotspot. AF Cam shows marginal evidence for a low-amplitude variation implying a very short orbital period of 76 min. IR colors of SS Aur, AH Eri, and IR Gem as well as the above four objects are used to place limits on the properties of the secondaries and the distances to these systems.

Avant-Propos

OpenAIRE

Ruppert, Helmut

2013-01-01

C’est à l’instigation de mon professeur, M. Eugen Wirth, que je me suis lancé dans ce travail. Lors d’un premier voyage au printemps 1966, il me fit ouvrir les yeux sur quelques-uns des importants problèmes de la géographie sociale et économique du Proche-Orient. Lors de voyages ultérieurs passés à parcourir et à arpenter avec moi d’autres villes orientales, le professeur Wirth m’a permis de comparer pour la ville de Beyrouth, grâce à une vue générale, les éléments proprement orientaux et ceu...

Pedestrian Inattention Blindness While Playing Pokémon Go as an Emerging Health-Risk Behavior: A Case Report.

Science.gov (United States)

Barbieri, Stefania; Vettore, Gianna; Pietrantonio, Vincenzo; Snenghi, Rossella; Tredese, Alberto; Bergamini, Mauro; Previato, Sara; Stefanati, Armando; Gaudio, Rosa Maria; Feltracco, Paolo

2017-04-01

Cases of trauma resulting from the use of mobile phones while driving motor vehicles have become quite common in recent years. Road injuries incurred by people playing video games on mobile phones (or other media devices) while walking have also become a cause for concern. Pokémon Go has been the world's most popular game since it was launched in July 2016, with more than 15 million players trying to catch all Pokémon available in the game; however, the case detailed here is the first reported accident in the medical literature caused by a pedestrian distracted by the game while crossing a street. We aim to provide additional information on the innovative nature of distractions that generate risks in road-users, and to explore the underreporting of pedestrian-motor vehicle collisions due to mobile device usage. We included in this case report a 25-year-old male who suddenly crossed a road while playing Pokémon Go and was hit by a van, reporting several injuries and being assisted by the Emergency Medical Service of our hospital (Padova, Italy). The patient's history, the circumstances in which the collision happened, imaging data, and clinical course information were recorded per our hospital's privacy policy. The patient hit by the van was playing Pokémon Go on his mobile phone while crossing a street, despite red traffic lights, which he did not notice due to of the distraction induced by the game. Mobile videogames that imply movement (ie, walking, running, cycling) to play are an effective way to improve physical activity practice, especially in adolescents and young adults. Nevertheless, cases like the one presented here point out that these games could pose a significant risk to users who play while walking, cycling, or driving in unsafe areas such as city streets, because players become distracted and may ignore surrounding hazards. Comprehensive, multilevel interventions are needed to reduce accidents caused by distraction, and to stress findings on the

Pokémon Go and the Law: Privacy, Intellectual Property, and Other Legal Concerns

OpenAIRE

Li, Tiffany

2017-01-01

Before the first lawsuits arrive, this article provides a brief analysis of some of the legal issues involved with the new hit mobile game, including: personal injury liability; privacy; intellectual property; trespass; augmented reality; and virtual currency. This is not an exhaustive list of every legal possibility inherent in the Pokémon Go world. These are just some of the legal issues at play when users, well, play. While this may seem like a long list of potential legal problems, the re...

The contribution of meteorological surveys to the analysis of forest ecosystems: the FutMon project

Directory of Open Access Journals (Sweden)

Salvati L

2013-09-01

Full Text Available Much of the wide variation in plant morphology, physiology and development biology is reflected in the capacity to adapt to climate changes. The aim of this paper is to contribute to the climate description of selected Italian forest sites (the CONECOFOR network where a permanent environmental monitoring was carried out since 1997 within the ICP-Forests, ICP-IM framework Forest Focus Reg. and the EU-funded FutMon research project.

99Mo production by 100Mo(n,2n)99Mo using accelerator neutrons

International Nuclear Information System (INIS)

Sato, Nozomi; Kawabata, Masako; Nagai, Yasuki; Hashimoto, Kazuyuki; Hatsukawa, Yuichi; Saeki, Hideya; Motoishi, Shoji; Kin, Tadahiro; Konno, Chikara; Ochiai, Kentaro; Takakura, Kosuke; Minato, Futoshi; Iwamoto, Osamu; Iwamoto, Nobuyuki; Hashimoto, Shintaro

2013-01-01

We proposed a new route to produce a medical radioisotope 99 Mo by the 100 Mo(n,2n) 99 Mo reaction using accelerator neutrons. A high-quality 99 Mo with a minimum level of radioactive waste can be obtained by the proposed reaction. The decay product of 99 Mo, 99m Tc, is separated from 99 Mo by the sublimation method. The proposed route could bring a major breakthrough in the solution of ensuring a constant and reliable supply of 99 Mo. (author)

Performance comparison of the MOXY and PortaMon near-infrared spectroscopy muscle oximeters at rest and during exercise

Science.gov (United States)

McManus, Chris J.; Collison, Jay; Cooper, Chris E.

2018-01-01

The purpose of the study was to compare muscle oxygenation as measured by two portable, wireless near-infrared spectroscopy (NIRS) devices under resting and dynamic conditions. A recently developed low-cost NIRS device (MOXY) was compared against an established PortaMon system that makes use of the spatially resolved spectroscopy algorithm. The influence of increasing external pressure on tissue oxygen saturation index (TSI) indicated that both devices are stable between 2 and 20 mmHg. However, above this pressure, MOXY reports declining TSI values. Analysis of adipose tissue thickness (ATT) and TSI shows a significant, nonlinear difference between devices at rest. The devices report similar TSI (%) values at a low ATT (major subsequent change between the devices occurring between 7 and 10 mm at ATT values >10 mm the difference remains constant (-14.7±2.8%). The most likely explanation for this difference is the small source-detector separation (2.5 cm) in the MOXY resulting in lower tissue penetration into muscle in subjects with higher ATT. Interday test-retest reliability of resting TSI was evaluated on five separate occasions, with the PortaMon reporting a lower coefficient of variation (1.8% to 2.5% versus 5.7% to 6.2%). In studies on male subjects with low ATT, decreases in the TSI were strongly correlated during isometric exercise, arterial occlusion, and incremental arm crank exercise. However, the MOXY reports a greater dynamic range, particularly during ischemia induced by isometric contraction or occlusion (Δ74.3% versus Δ43.7% hyperemia MAX-occlusion MIN). This study shows that in this subject group both MOXY and PortaMon produce physiologically credible TSI measures during rest and exercise. However, the absolute values obtained during exercise are generally not comparable between devices unless corrected by physiological calibration following an arterial occlusion.

Upgrades of the RadMon V6 and its Integration on a Nanosatellite for the Analysis and the Comparative Study of the CHARM and Low Earth Orbit Environments

CERN Document Server

AUTHOR|(CDS)2080738; PERONNARD Paul, CERN

Radiation fields in the CERN accelerator complex are characterized by mixed particles with broad energy ranges. A Radiation Monitoring System, called "RadMon", was developed for the distributed, on-line measurement of the complex radiation fields and their effect on the electronics installed in areas with a harsh radiation environment. The most recent version of the RadMon revealed a critical issue soon after deployment in the tunnel and the experimental areas. Multiple Cell Upsets (MCUs) arising from microlatchup events started showing up on the SRAM-based particle flux sensors equipped by the system, ultimately affecting the measurement and resulting in corrupted data and accuracy losses. A study of the generation of this effect was performed, and a solution using an on-line detection and correction algorithm embedded on an FPGA, was evaluated and implemented on the RadMon device. Furthermore, in the framework of the project CELESTA, a feasibility study was carried out to validate the adaptation of the RadM...

Økologisk risikovurdering af genmodificeret insektresistent majs MON89034 i anmeldelse vedr. markedsføring til import for viderebearbejdning og til dyrkning under Forordning 1829/2003/EF

DEFF Research Database (Denmark)

Kjellsson, Gøsta; Damgaard, Christian; Sørensen, Jesper Givskov

2012-01-01

"Den genmodificerede, dobbelt insektresistente MON89034-majs adskiller sig fra konventionel majs ved at have indsat gener der gør planterne resistente mod angreb af majsmøllet og beslægtede sommerfugle såsom majsboreren, der dog for nærværende ikke er et skadedyr i Danmark. GM-majsen søges godken......89034-maize when used for cultivation. DCE suggests however, that the close surroundings of fields with MON89034-maize are monitored to detect any adverse effects to butterflies in the close field surroundings. "...

Field-tuned superconductor-insulator transitions and Hall resistance in thin polycrystalline MoN films

Science.gov (United States)

Makise, Kazumasa; Ichikawa, Fusao; Asano, Takayuki; Shinozaki, Bunju

2018-02-01

We report on the superconductor-insulator transitions (SITs) of disordered molybdenum nitride (MoN) thin films on (1 0 0) MgO substrates as a function of the film thickness and magnetic fields. The T c of the superconducting MoN films, which exhibit a sharp superconducting transition, monotonically decreases as the normal state R sq increases with a decreasing film thickness. For several films with different thicknesses, we estimate the critical field H c and the product zν  ≃  0.6 of the dynamical exponent z and the correlation length exponent ν using a finite scaling analysis. The value of this product can be explained by the (2  +  1) XY model. We found that the Hall resistance ΔR xy (H) is maximized when the magnetic field satisfies H HP(T) \\propto |1  -  T/T C0| in the superconducting state and also in the normal states owning to the superconducting fluctuation corresponding to the ghost critical magnetic field. We measured the Hall conductivity δσ xy (H)  =  σ xy (H)  -  σ xyn and fit the Gaussian approximation theory for δσ xy (H) to the experimental data. Agreement between the data and the theory beyond H c suggests the survival of the Cooper pair in the insulating region of the SIT.

L’émoi des demoiselles en voyage. Du voyage dans quelques journaux intimes de jeunes filles du XIXe siècle

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Martine Sonnet

2012-06-01

Full Text Available Le corpus de journaux intimes de jeunes filles du XIXe siècle constitué par Philippe Lejeune (Le moi des demoiselles : enquête sur le journal de jeune fille, 1993 se prête à une lecture  mettant en évidence la rupture provoquée par le voyage dans le terne ordinaire des jours de jeunes bourgeoises ou de jeunes aristocrates. Une trentaine de journaux évoquant des voyages dévoilent l’ambivalence des émotions que suscitent des déplacements, toujours accomplis sous bonne escorte, remplissant le plus souvent des fonctions combinées : touristiques, familiales, thérapeutiques, éducatives etc.. Joie et anxiété des préparatifs et du départ, craintes et désirs de rencontres dans la promiscuité des chemins de fer, excitation au passage des frontières et soulagement de rentrer chez soi saine et sauve : autant de sentiments confiés à leurs journaux par les jeunes diaristes voyageuses.Travelling Demoiselles’ Emotions : travel in girls’ diaries in the nineteenth centuryThe collection of nineteenth century’s girls’ private diaries studied by Philippe Lejeune (Le moi des demoiselles : enquête sur le journal de jeune fille, 1993 reveals the way travel interrupted the often dull routine of young bourgeois and aristocratic girls. About thirty diaries display the mixed feelings that travel generated for these girls who left home, most often with family members, to discover new places, attend family events, restore health, or acquire education, etc. This selection of texts highlights such topics as the pleasure and anxiety of leaving home, the fear and desire of railway travels’ unexpected encounters, the exhilaration in crossing borde.

Retraduzir a obra para traduzir o rascunho: tradução da poética do rascunho em Mon coeur mis à nu, de Charles Baudelaire

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Oliveira, Thiago Mattos de

2015-10-01

Full Text Available Similarly to Fernando Pessoa’s Livro do Desassossego, Mon coeur mis à nu presents itself as an unfinished work, constituted by disperse, provisional, sometimes incomplete notes. Some critics believe that such works were not meant to be oeuvres, but drafts, works in progress, unachieved-unachievable texts. Based on Didier’s (1973 notion of draft poetics, it is now possible to consider that incompleteness is inherent to these works; they constitute themselves in and through their incompleteness. Provisionality, hesitancy, unfinishedness are constitutive of this draft poetics. It is our aim to discuss and work out a way of translating Mon coeur mis à nu by building on its procedural and incomplete dimension, seeking to highlight the many ways of ordering and structuring the text, and paying attention to the materiality of the manuscript and its revision process. Therefore, I propose resorting to hypertext, a translational and editorial strategy that would allow a rhizomatic and multicursal reading of this material, enabling the reader to experience the haunting and the “monstrosity” of the moving textuality that appears in Mon coeur mis à nu.

Le khatchkar ou la construction de sa petite Arménie.

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Marie-Blanche Fourcade

2007-03-01

Full Text Available « C’est une reproduction d’un khatchkar que mon fils m’a rapporté d’Arménie. Je l’ai mis dans un endroit choisi pour moi, c’est comme une communion avec l’Arménie » disait Vichen lors d’un entretien que je menais sur le patrimoine domestique de la diaspora arménienne au Québec. La plaque de tuff ornée d’une croix 1 , surmontée de motifs végétaux et géométriques est installée sur le manteau de sa cheminée, dans le sous-sol aménagé de sa maison. Elle ...

Du rapport entre le harcèlement et l’hégémonie intellectuelle

OpenAIRE

Berger, Vincent

2015-01-01

Mesdames, Messieurs, Chers collègues, Je suis très heureux que mon tout dernier discours ici à la Présidence de Paris Diderot – la fin même de cette intervention sera l’occasion pour moi de prononcer mes derniers mots de Président – le soit sur le thème des relations entre les hommes et les femmes à l’Université. Vous êtes ici dans  un  lieu  universitaire  engagé  sur  la  thématique de l’égalité entre les femmes et les hommes. Le harcèlement entre personnels me semble  un  problème  relat...

Investigation of Segregated Business Ethics Elements Influence on Results of Service Enterprises Activity Verslo etikos elementų įtakos paslaugų įmonės veiklos rezultatams analizė

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Kristina Luebcke

2011-02-01

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Verslo ir rinkodaros etikos problemas Lietuvoje nagrinėjo įvairūs autoriai. Nepaisant to, nėra vienos nuomonės dėl atskirų etikos elementų įtakos įmonės veiklos rezultatams. Šis tyrimas yra skirtas nustatyti, ar atskiri verslo etikos elementai daro įtaką paslaugų įmonės veiklos rezultatams. Buvo tikrinama prielaida, kad yra galimybė įvertinti atskirų etikos elementų įtakos dydį. Tyrimo metu nustatyta kad, verslo etikos normų laikymasis daro didelę įtaką įmonės veiklos rezultatams. Nustačius atskirų verslo etikos ir paslaugų įmonės veiklos rezultatų tarpusavio koreliacinį priklausomumą, išryškėjo didžiausia atskirų verslo etikos elementų įtaka atskiriems įmonės konkurencingumo elementams. Išanalizavus metinės paslaugų įmonių veiklos rezultatus, atspindėtus verslo masinėse informacijos priemonėse, nustatyta tiesioginė verslo etikos įtaka įmonės pelnui ir pardavimų rezultatams. Straipsnyje pateikiamas svarbiausių verslo etikos elementų įtakos paslaugų įmonės veiklos rezultatams modelis, kuris tinka visoms paslaugų sektoriaus įmonėms. Temos naujumas pasireiškia tuo, kad iki šiol nebuvo nustatyta tiesioginė verslo etikos įtaka įmonės pelnui ir pardavimų rezultatams.

Raktiniai žodžiai:

Pokémon, gotta catch them all: comunidade, jogo e memória = Pokémon, gotta catch them all: community, game and memory

Directory of Open Access Journals (Sweden)

Siqueira, Camila Freitas

2016-01-01

Full Text Available O presente artigo propõe uma reflexão teórica sobre as interações entre memória e comunidade no gameplay de Pokémon Red (1996 via Twitch, o qual, a partir da mobilização de uma inteligência coletiva, deu origem a uma memória coletiva embasada na ressignificação da narrativa do jogo pelos próprios usuários. Sob os pilares da cultura remix, este texto destaca a importância da participação e, também, da mobilização de tal inteligência, a fim de cooperar tanto na manutenção quanto na criação de uma memória relacionada à comunidade na rede. Ao observar o conteúdo narrativo do objeto desta análise, foi identificada a construção de um universo extradiegético, diretamente relacionado à comunidade e ao gameplay

Origins of Sinuous and Braided Channels on Ascraeus Mons, Mars - A Keck Geology Consortium Undergraduate Research Project

Science.gov (United States)

de Wet, A. P.; Bleacher, J. E.; Garry, W. B.

2012-01-01

Water has clearly played an important part in the geological evolution of Mars. There are many features on Mars that were almost certainly formed by fluvial processes -- for example, the channels Kasei Valles and Ares Vallis in the Chryse Planitia area of Mars are almost certainly fluvial features. On the other hand, there are many channel features that are much more difficult to interpret -- and have been variously attributed to volcanic and fluvial processes. Clearly unraveling the details of the role of water on Mars is extremely important, especially in the context of the search of extinct or extant life. In this project we built on our recent work in determining the origin of one channel on the southwest rift apron of Ascraeus Mons. This project, funded by the Keck Geology Consortium and involving 4 undergraduate geology majors took advantage of the recently available datasets to map and analyze similar features on Ascraeus Mons and some other areas of Mars. A clearer understanding of how these particular channel features formed might lead to the development of better criteria to distinguish how other Martian channel features formed. Ultimately this might provide us with a better understanding of the role of volcanic and fluvial processes in the geological evolution of Mars.

El origen glaciar de la aureola del volcán Arsia Mons, Marte

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Anguita Virella, F.

1994-08-01

Full Text Available Huge lobate deposits called aureoles are covering the base of the giant Martian volcanic constructs of Tharsis dome. The origin of these structures has been a matter of debate between two competing hypotheses: volcanic landslides or mountain glaciers. Here we consider the most important of the aureoles, near Arsia Mons, concluding that the glacier model explains best the deposit features, such as the layering, the ridges (interpreted as glaciotectonic ones, and the lobated terrain. We then discuss the fit of these proposed glacier deposits in the present paleoclimatic Martian models. The aureoles could be key elements in the confirmation of the «Baker cycle» model of repeated episodes of temperate, humid, sea-dominated climates coincident in time with the outflow channels activity.Al pie de los grandes volcanes marcianos del domo de Tharsis aparecen unas formas lobuladas que han recibido el nombre de aureolas. El origen de estas estructuras ha sido objeto de un largo debate entre dos hipótesis principales que las interpretan como deslizamientos de ladera o como glaciares de montaña. En este trabajo se estudia la mejor desarrollada de estas aureolas, la de Arsia Mons, llegándose a la conclusión de que la hipótesis glaciar explica mejor las características del depósito, y en concreto la existencia de estratificación, las crestas (que se interpretan como glaciotectónicas y los terrenos lobulados. Por último se discute la conexión de estos depósitos con los modelos paleoclimáticos actuales sobre Marte, lo que lleva a la conclusión de que las aureolas deben ser depósitos glaciares recientes relacionados con repetidos episodios de clima cálido (ciclos de Baker, provocados por la acción de los canales de desbordamiento.

Estimation de la survie des alevins de carpe (C. carpio au cours de leur premier mois d'existence

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MOREAU J.

1979-10-01

Full Text Available Des observations réalisées sur deux stations piscicoles de Madagascar, dans des étangs ne recevant ni engrais ni nourriture, révèlent qu'au cours de leur premier mois les alevins de carpe (C. carpio subissent des mortalités voi-sines de 50 %. Ces dernières sont encore plus élevées en début et en fin de saison de reproduction. Au début, les fortes mortalités sont dues à la température trop basse et aux disponibilités alimentaires insuffisantes ; en fin de saison de reproduction, la température trop élevée et la mauvaise qualité des œufs sont sans doute en cause. Une fumure adéquate des étangs de grossissement des alevins et une alimentation correcte des géniteurs permettront peut-être de diminuer ces mortalités.

SCUBA and HIRES Results for Protostellar Cores in the MON OB1 Dark Cloud

Science.gov (United States)

Wolf-Chase, G.; Moriarty-Schieven, G.; Fich, M.; Barsony, M.

1999-05-01

We have used HIRES-processing of IRAS data and point-source modelling techniques (Hurt & Barsony 1996; O'Linger 1997; Barsony et al. 1998), together with submillimeter continuum imaging using the Submillimeter Common-User Bolometer Array (SCUBA) on the 15-meter James Clerk Maxwell Telescope (JCMT), to search CS cores in the Mon OB1 dark cloud (Wolf-Chase, Walker, & Lada 1995; Wolf-Chase & Walker 1995) for deeply embedded sources. These observations, as well as follow-up millimeter photometry at the National Radio Astronomy Observatory (NRAO) 12-meter telescope on Kitt Peak, have lead to the identification of two Class 0 protostellar candidates, which were previously unresolved from two brighter IRAS point sources (IRAS 06382+0939 & IRAS 06381+1039) in this cloud. Until now, only one Class 0 object had been confirmed in Mon OB1; the driving source of the highly-collimated outflow NGC 2264 G (Ward-Thompson, Eiroa, & Casali 1995; Margulis et al. 1990; Lada & Fich 1996), which lies well outside the extended CS cores. One of the new Class 0 candidates may be an intermediate-mass source associated with an H_2O maser, and the other object is a low-mass source which may be associated with a near-infrared jet, and possibly with a molecular outflow. We report accurate positions for the new Class 0 candidates, based on the SCUBA images, and present new SEDs for these sources, as well as for the brighter IRAS point sources. A portion of this work was performed while GWC held a President's Fellowship from the University of California. MB and GWC gratefully acknowledge financial support from MB's NSF CAREER Grant, AST97-9753229.

Misalignment of Lava Flows from Topographic Slope Directions Reveals Late Amazonian Deformation at Arsia Mons, Mars

Science.gov (United States)

Waring, B. A.; Chadwick, J.; McGovern, P. J., Jr.; Tucker, W.

2017-12-01

Arsia Mons is the southernmost of the three large Tharsis Montes near the equator of Mars and one of the largest volcanoes in the solar system. The main edifice of Arsia is about 440 km in diameter, the summit is over 9 km above the surrounding plains and has a pronounced 110 km caldera. Like the other Tharsis volcanoes, Arsia has a large, Late Amazonian glacial deposit on its NW flank. Previous crater retention studies for lava flows on Arsia have shown that the volcano experienced significant volcanic activity in the past 200 Ma. In this study, numerous long (>25 km), thin lava flows on the plains surrounding Arsia were mapped and used as indicators of the topographic slope direction at the time of their emplacement. The azimuthal orientation of each flow was compared with the present-day slope directions on the surrounding plains, derived from Mars Orbiter Laser Altimeter (MOLA) topographic data. The results reveal regions around Arsia where the flows no longer conform to the topography, indicating deformation in the time since the flows where emplaced. In a region of Daedalia Planum to the SE of Arsia, modern slope directions adjacent to 40 long lava flows are consistently misaligned from the paleo-slopes indicated by the lava flow orientations, with an angular offset that averages 7.2° in the clockwise direction. Crater size-frequency measurements for these tilted plains using CraterStats software indicate that the deformation responsible for the misaligned flows took place since 330 ± 10 Ma. Conversely, part of Daedalia Planum to the southwest of Arsia is younger, with a crater retention age of 160 ± 6 Ma, and this area shows no consistent flow-topography misalignments. These observations suggest that extensive regional deformation occurred between the two dates, consistent with other evidence for significant volcanism at Arsia in the Late Amazonian at about 200 Ma. Geophysical modelling using the finite element program COMSOL Multiphysics is planned to

Influence of sediment on the fate and toxicity of a polyethoxylated tallowamine surfactant system (MON 0818) in aquatic microcosms

Science.gov (United States)

Wang, N.; Besser, J.M.; Buckler, D.R.; Honegger, J.L.; Ingersoll, C.G.; Johnson, B. Thomas; Kurtzweil, M.L.; MacGregor, J.; McKee, M.J.

2005-01-01

The fate and toxicity of a polyethoxylated tallowamine (POEA) surfactant system, MON 0818, was evaluated in water–sediment microcosms during a 4-d laboratory study. A surfactant solution of 8 mg l−1 nominal concentration was added to each of nine 72-l aquaria with or without a 3-cm layer of one of two natural sediments (total organic carbon (TOC) 1.5% or 3.0%). Control well water was added to each of nine additional 72-l aquaria with or without sediment. Water samples were collected from the microcosms after 2, 6, 24, 48, 72, and 96 h of aging to conduct 48-h toxicity tests with Daphnia magna and to determine surfactant concentrations. Elevated mortality of D. magna (43–83%) was observed in overlying water sampled from water-only microcosms throughout the 96-h aging period, whereas elevated mortality (23–97%) was only observed in overlying water sampled from water–sediment microcosms during the first 24 h of aging. Measured concentrations of MON 0818 in water-only microcosms remained relatively constant (4–6 mg l−1) during the 96-h period, whereas the concentrations in overlying water from microcosms containing either of the two types of sediment dissipated rapidly, with half-lives of 13 h in the 3.0% TOC sediment and 18 h in the 1.5% TOC sediment. Both toxicity and the concentration of MON 0818 in overlying water decreased more rapidly in microcosms containing sediment with the higher percent TOC and clay and with a higher microbial biomass. Mortality of D. magna was significantly correlated with surfactant concentrations in the overlying water. These results indicate that the toxicity of the POEA surfactant in water rapidly declines in the presence of sediment due to a reduction in the surfactant concentration in the overlying water above the sediment.

Taking stock of the ethical foundations of international health research: pragmatic lessons from the IU-Moi Academic Research Ethics Partnership.

Science.gov (United States)

Meslin, Eric M; Were, Edwin; Ayuku, David

2013-09-01

It is a sine qua non that research and health care provided in international settings raise profound ethical questions when different cultural and political values are implicated. Yet ironically, as international health research expands and as research on ethical issues in international health research broadens and deepens, we appear to have moved away from discussing the moral foundations of these activities. For international health research to thrive and lead to the kind of benefits it is capable of, it is helpful to occasionally revisit the foundational premises that justify the enterprise as a whole. We draw on the experience of the Indiana University-Moi University Academic Research Ethics Partnership, an innovative bioethics training program co-located in Indianapolis and Eldoret, Kenya to highlight the changing nature of ethical issues in international health research and the ongoing practical challenges.

Measurement of formation cross-section of 99Mo from the 98Mo(n,γ) and 100Mo(n,2n) reactions.

Science.gov (United States)

Badwar, Sylvia; Ghosh, Reetuparna; Lawriniang, Bioletty M; Vansola, Vibha; Sheela, Y S; Naik, Haladhara; Naik, Yeshwant; Suryanarayana, Saraswatula V; Jyrwa, Betylda; Ganesan, Srinivasan

2017-11-01

The formation cross-section of medical isotope 99 Mo from the 98 Mo(n,γ) reaction at the neutron energy of 0.025eV and from the 100 Mo(n,2n) reaction at the neutron energies of 11.9 and 15.75MeV have been determined by using activation and off-line γ-ray spectrometric technique. The thermal neutron energy of 0.025eV was used from the reactor critical facility at BARC, Mumbai, whereas the average neutron energies of 11.9 and 15.75MeV were generated using 7 Li(p,n) reaction in the Pelletron facility at TIFR, Mumbai. The experimentally determined cross-sections were compared with the evaluated nuclear data libraries of ENDF/B-VII.1, CENDL-3.1, JENDL-4.0 and JEFF-3.2 and are found to be in close agreement. The 100 Mo(n,2n) 99 Mo reaction cross-sections were also calculated theoretically by using TALYS-1.8 and EMPIRE-3.2 computer codes and compared with the experimental data. Copyright © 2017 Elsevier Ltd. All rights reserved.

Natural variation explains most transcriptomic changes among maize plants of MON810 and comparable non-GM varieties subjected to two N-fertilization farming practices

Czech Academy of Sciences Publication Activity Database

Coll, A.; Nadal, A.; Collado, R.; Capellades, G.; Kubista, Mikael; Messeguer, J.; Pla, M.

2010-01-01

Roč. 73, č. 3 (2010), s. 349-362 ISSN 0167-4412 Institutional research plan: CEZ:AV0Z50520701 Keywords : GMO (Genetically Modified Organism) * MON810 * Maize * Transcriptome Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.149, year: 2010

Café crème méthode de français : niveau 1

CERN Document Server

Kaneman-Pougatch, Massia; Beacco di Giura, Marcella; Jennepin, Dominique

1997-01-01

Une méthode de français pour grands adolescents et adultes pour assurer un apprentissage complet, pratique, dynamique et efficace. 80 ? 100 heures de cours. 16 unité de 8 pages organisées en quatre parties, qui reprennent les quatre types de discours : 1 - Bonjour ! (l'informatif) 2 - A mon avis... (l'argumentatif) 3 - Dis pourquoi... (l'explicatif) 4 - Alors raconte... ( le narratif) Chaque unité comprend : - 3 pages "" Découvertes "" Activités de compréhension, exploitation et réemploi : la découverte de la langue par les activités. - 3 pages "" Boîte ? outils "" 1 page Vocabulaire et Phonétique et 2 pages Grammaire (tableaux, exercices systématiques d'acquisition et animation grammaticale) : la systématisation formelle. - 2 pages "" Paroles en liberté "" Dialogues avec une exploitation orale et écrite : l'élargissement et le réemploi. Toutes les 4 unités : un bilan-test de 2 pages et un supplément de civilisation (3 pages). En annexe : un précis grammatical et un lexique multilingue.

Pour une automythanalyse au risque de la Science Fiction et des Sciences Occultes

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Christian Gatard

2014-12-01

Full Text Available On peut considérer les mythes comme des récits que l’humanité se raconte pour affronter les temps difficiles. C’est Frazer dans le Rameau d’Or qui le formule ainsi. J’aime bien les ethnologues un peu démonétisés comme lui. C’est dans les vieilles poêles qu’on fait les meilleures omelettes. Et puis, il y a toujours eu des temps difficiles. Et tout le monde a toujours pensé que le futur serait difficile. On a donc toujours besoin de récits. Mais comment s’en servir ? C’est là qu’intervient l’automythanalyse considérée instrument de navigation sur le fleuve du devenir. Les travaux d’Hervé Fischer ont montré combien la mythanalyse est un outil essentiel du jardinage de l’inconscient, engin technique spécialisé dans les grands travaux de l’imaginaire. Je propose ici d’adapter l’engin à ma propre course vers les étoiles mais vous allez voir que cela va pouvoir vous servir à vous aussi, lecteur.

Dielectric properties of lava flows west of Ascraeus Mons, Mars

Science.gov (United States)

Carter, L.M.; Campbell, B.A.; Holt, J.W.; Phillips, R.J.; Putzig, N.E.; Mattei, S.; Seu, R.; Okubo, C.H.; Egan, A.F.

2009-01-01

The SHARAD instrument on the Mars Reconnaissance Orbiter detects subsurface interfaces beneath lava flow fields northwest of Ascraeus Mons. The interfaces occur in two locations; a northern flow that originates south of Alba Patera, and a southern flow that originates at the rift zone between Ascraeus and Pavonis Montes. The northern flow has permittivity values, estimated from the time delay of echoes from the basal interface, between 6.2 and 17.3, with an average of 12.2. The southern flow has permittivity values of 7.0 to 14.0, with an average of 9.8. The average permittivity values for the northern and southern flows imply densities of 3.7 and 3.4 g cm-3, respectively. Loss tangent values for both flows range from 0.01 to 0.03. The measured bulk permittivity and loss tangent values are consistent with those of terrestrial and lunar basalts, and represent the first measurement of these properties for dense rock on Mars. Copyright 2009 by the American Geophysical Union.

ReadMON: a portable readout system for the CERN PH-RADMON sensors

CERN Document Server

Mateu, Isidre; Gorine, Georgi; Moll, Michael; Pezzullo, Giuseppe; Ravotti, Federico

2018-01-01

PH-RADMON sensors are extensively used for radiation monitoring in the LHC experiments. Here, ReadMON, a dedicated and portable readout system for non-LHC applications, is presented. The system is able to source currents up to 32 mA and measure voltages up to 125 V, covering the full operational range of all dosimeters onboard the PH-RADMON sensor. Thus, the total measurement range of the system goes from 0.01 Gy to hundreds of kGy Total Ionizing Dose, and from few 10^10 neq/cm2 to 10^15 neq/cm2 1MeV neutron equivalent fluence. Different tests have been carried out at CERN IRRAD facility to prove the system concept and analyze its performance. Errors of only a few percent with respect to the readout done with a commercial Source Measuring Unit were found.

Influencia de la incorporación de un co-monómero alcalino e hidroxiapatita en las propiedades de cementos óseos acrílicos

Directory of Open Access Journals (Sweden)

Karen Lozano

2013-01-01

Full Text Available Se formularon cementos óseos acrílicos utilizando una relación sólido / líquido de 2. El componente líquido se basó en metacrilato de metilo (MMA, como monómero y dimetil-p-toluidina (2.5% como acelerador; a su vez, el componente sólido consistió en perlas de polimetacrilato de metilo (PMMA como carga, sulfato de bario como agente radiopaco y peróxido de benzoilo (2% como iniciador. Finalmente, una hidroxiapatita como carga bioactiva y un metacrilato de dimetil amino etilo (DMAEM como co-monómero alcalino, fueron incorporados en diferentes porcentajes (0-20% p/p, para el primero y 0-10% p/p, para el segundo. Como era de esperarse, las muestras elaboradas con las formulaciones de cementos óseos acrílicos sin modificar, presentaron calores de reacción elevados (>80ºC y una resistencia a la compresión (124.0 MPa por encima de lo especificado en la norma ISO 5833. Con la incorporación de la hidroxiapatita y el co-monómero alcalino, se presentaron bajas temperaturas de polimerización, bajos módulos y resistencias mecánicas, así como la fijación de una capa similar a la apatita biológica en la superficie del material después de su inmersión por 30 días en un fluido biológico simulado.

Actividad Monástica y acción política en Fructuoso de Braga

Directory of Open Access Journals (Sweden)

López Quiroga, Jorge

2002-06-01

Full Text Available The social and political context of Hispania in the second half of 7th century was very difficult. San Fructuoso and his ideas were different from the habitual ones. His religious model and his monastic reform are new in the visigoth world. In this work we analyze the foundations of Fructuoso in the Southeastern of the Iberian Peninsula (Vid. Fruct. 14. This work reflects the religious, social and political consequences of the monacato in the reorganization of Iberian society at the end of the antiquity.

En el marco de un contexto socio-político particularmente difícil, como es el que correspondería a la Hispania visigoda de la segunda mitad del siglo VII d. C., la aparición de una figura como Fructuoso supondría un auténtico tournant no sólo en lo que respecta al modelo religioso que propugna, sino, sobre todo, en el conflicto latente entre el tipo de vida monástica «fructuosiana» y el Estado visigodo, personalizado aquí en la figura del monarca. En este breve trabajo, el episodio referente a las fundaciones monásticas de Fructuoso en el Sureste Peninsular (narrado en la Vit Fruct. 14 nos servirá de hilo conductor para hacer una pequeña reflexión sobre las implicaciones no sólo religiosas, sino, sobre todo, sociales y políticas del monacato como uno de los exponentes del proceso de desestructuración que conduce al 'final de la Antigüedad' en la Península Ibérica.

WEclMon - A simple and robust camera-based system to monitor Drosophila eclosion under optogenetic manipulation and natural conditions.

Directory of Open Access Journals (Sweden)

Franziska Ruf

Full Text Available Eclosion in flies and other insects is a circadian-gated behaviour under control of a central and a peripheral clock. It is not influenced by the motivational state of an animal, and thus presents an ideal paradigm to study the relation and signalling pathways between central and peripheral clocks, and downstream peptidergic regulatory systems. Little is known, however, about eclosion rhythmicity under natural conditions, and research into this direction is hampered by the physically closed design of current eclosion monitoring systems. We describe a novel open eclosion monitoring system (WEclMon that allows the puparia to come into direct contact with light, temperature and humidity. We demonstrate that the system can be used both in the laboratory and outdoors, and shows a performance similar to commercial closed funnel-type monitors. Data analysis is semi-automated based on a macro toolset for the open imaging software Fiji. Due to its open design, the WEclMon is also well suited for optogenetic experiments. A small screen to identify putative neuroendocrine signals mediating time from the central clock to initiate eclosion showed that optogenetic activation of ETH-, EH and myosuppressin neurons can induce precocious eclosion. Genetic ablation of myosuppressin-expressing neurons did, however, not affect eclosion rhythmicity.

Transcriptomic Analysis of Intestinal Tissues from Two 90-Day Feeding Studies in Rats Using Genetically Modified MON810 Maize Varieties.

Science.gov (United States)

Sharbati, Jutta; Bohmer, Marc; Bohmer, Nils; Keller, Andreas; Backes, Christina; Franke, Andre; Steinberg, Pablo; Zeljenková, Dagmar; Einspanier, Ralf

2017-01-01

Background: Global as well as specific expression profiles of selected rat tissues were characterized to assess the safety of genetically modified (GM) maize MON810 containing the insecticidal protein Cry1Ab. Gene expression was evaluated by use of Next Generation Sequencing (NGS) as well as RT-qPCR within rat intestinal tissues based on mandatory 90-day rodent feeding studies. In parallel to two 90-day feeding studies, the transcriptional response of rat tissues was assessed as another endpoint to enhance the mechanistic interpretation of GM feeding studies and/or to facilitate the generation of a targeted hypothesis. Rats received diets containing 33% GM maize (MON810) or near-isogenic control maize. As a site of massive exposure to ingested feed the transcriptomic response of ileal and colonic tissue was profiled via RT-qPCR arrays targeting apoptosis, DNA-damage/repair, unfolded protein response (UPR). For global RNA profiling of rat ileal tissue, we applied NGS. Results: No biological response to the GM-diet was observed in male and in female rat tissues. Transcriptome wide analysis of gene expression by RNA-seq confirmed these findings. Nevertheless, gene ontology (GO) analysis clearly associated a set of distinctly regulated transcripts with circadian rhythms. We confirmed differential expression of circadian clock genes using RT-qPCR and immunoassays for selected factors, thereby indicating physiological effects caused by the time point of sampling. Conclusion: Prediction of potential unintended effects of GM-food/feed by transcriptome based profiling of intestinal tissue presents a novel approach to complement classical toxicological testing procedures. Including the detection of alterations in signaling pathways in toxicity testing procedures may enhance the confidence in outcomes of toxicological trials. In this study, no significant GM-related changes in intestinal expression profiles were found in rats fed GM-maize MON810. Relevant alterations of

Toward metrological traceability for DNA fragment ratios in GM quantification. 3. Suitability of DNA calibrants studied with a MON 810 corn model.

Science.gov (United States)

Charels, Diana; Broeders, Sylvia; Corbisier, Philippe; Trapmann, Stefanie; Schimmel, Heinz; Emons, Hendrik

2007-05-02

The quantification of GMOs by real-time PCR relies on an external calibrant. In this paper the suitability of two DNA calibrants, genomic DNA from plant leaves and plasmidic DNA, was investigated. The PCR efficiencies, the correlation coefficients of the calibration curves, and the ratios between PCR efficiencies of transgenic and endogenous sequences were compared for both calibrants using 59 data sets produced by 43 laboratories. There were no significant differences between plasmidic and genomic DNA except for the PCR efficiencies of the calibration curves for the transgene of the construct-specific real-time PCR method. In the GM system investigated, PCR efficiencies of plasmidic calibrants were slightly closer to the PCR efficiencies observed for the unknowns than those of the genomic DNA calibrant. Therefore, plasmidic DNA was the more suitable calibrant for the PCR measurements on genomic DNA extracted from MON 810 seeds. It is shown that plasmidic DNA is an appropriate choice for the calibration of measurements of MON 810 corn with respect to the DNA copy number ratio.

Recurrence Rate and Magma Effusion Rate for the Latest Volcanism on Arsia Mons, Mars

Science.gov (United States)

Richardson, Jacob A.; Wilson, James A.; Connor, Charles B.; Bleacher, Jacob E.; Kiyosugi, Koji

2016-01-01

Magmatism and volcanism have evolved the Martian lithosphere, surface, and climate throughout the history of Mars. Constraining the rates of magma generation and timing of volcanism on the surface clarifies the ways in which magma and volcanic activity have shaped these Martian systems. The ages of lava flows on other planets are often estimated using impact crater counts, assuming that the number and size-distribution of impact craters per unit area reflect the time the lava flow has been on the surface and exposed to potential impacts. Here we show that impact crater age model uncertainty is reduced by adding stratigraphic information observed at locations where neighboring lavas abut each other, and demonstrate the significance of this reduction in age uncertainty for understanding the history of a volcanic field comprising 29 vents in the 110-kilometer-diameter caldera of Arsia Mons, Mars. Each vent within this caldera produced lava flows several to tens of kilometers in length; these vents are likely among the youngest on Mars, since no impact craters in their lava flows are larger than 1 kilometer in diameter. First, we modeled the age of each vent with impact crater counts performed on their corresponding lava flows and found very large age uncertainties for the ages of individual vents, often spanning the estimated age for the entire volcanic field. The age model derived from impact crater counts alone is broad and unimodal, with estimated peak activity in the field around 130Ma (megaannum, 1 million years). Next we applied our volcano event age model (VEAM), which uses a directed graph of stratigraphic relationships and random sampling of the impact crater age determinations to create alternative age models. Monte Carlo simulation was used to create 10,000 possible vent age sets. The recurrence rate of volcanism is calculated for each possible age set, and these rates are combined to calculate the median recurrence rate of all simulations. Applying this

Pokémon Go: uma análise da realidade como entretenimento

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Karen Danielle Magri Ferreira Razera

2017-07-01

Full Text Available This article aims to analyze the repercussion of the Pokémon Go game to investigate the influence of the media on the behavior of the players, based on articles from the newspaper Folha de São Paulo. The critical theory of society was the theoretical basis that guided the analyzes, because it explains the social contradictions of this society of classes and their concepts about the formation of individuals. It was observed that the articles of the newspaper, mostly encourage the players in positive aspects of the game. The criticism of the game can be understood in its contradiction, because no one escapes of the cultural industry. From the analysis, it’s observed several characteristics of the cultural industry, which is the entertainment industry, making reality itself entertaining and encouraging the understanding that life don’t be taken so seriously.

East Part of Sapas Mons with Flooded Crater

Science.gov (United States)

1991-01-01

This Magellan image centered near 9.6 degrees north latitude, 189.5 degrees east longitude of an area 140 kilometers (87 miles) by 110 kilometers (68 miles) covers part of the eastern flank of the volcano Sapas Mons on the western edge of Atla Regio. The bright lobate features along the southern and the western part of the image, oriented in northeast to southwest directions, are lava flows that are rough at the 12.6 centimeter wavelength of the radar. These flows range in width from 5 kilometers to 25 kilometers (3 to 16 miles) with lengths of 50 kilometers to 100 kilometers (31 to 62 miles), extending off the area shown here. Additional radar-dark (smooth) flows are also present. The radar-bright linear structures in the northwest part of the image are interpreted to be faults and fractures possibly associated with the emplacement of magma in the subsurface. Located near the center of the image is a 20 kilometer (12 mile) diameter impact crater. This crater is superimposed on a northeast/southwest trending fracture while the southern part of the crater's ejecta blanket is covered by a 6 kilometer (4 mile) wide radar-bright lava flow. These relations indicate that the crater post dates an episode of fracturing and is older than the lava flows covering its southern edge. This is one of only a few places on Venus in which an impact crater is seen to be covered by volcanic deposits.

El papel de la contabilidad monástica a lo largo de la historia en el orbe cristiano. Una revisión

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Lorenzo Maté Sadornil

2017-07-01

Este análisis revela una diversidad de objetivos para los que esta ha resultado de utilidad. Ha supuesto un elemento clave para la supervivencia de estas instituciones a lo largo de los siglos, razón por la cual se le presta una atención primordial en las normas de gobierno de las distintas órdenes monásticas.

Explanation of changes of stellar radiation polarization by means of an ''active longitudes'' hypothesis with U Mon as an example

International Nuclear Information System (INIS)

Polyakova, T.A.

1980-01-01

The hypothesis explaining the variability of some stars with U Mon as an example resulting from antipodal active regions on their surface is discussed qualitatively. The plane of polarization is determined by average magnetic field of the bipolar active region. The changes of polarization and brightness are assumed to be connected with the star rotation. The rotation period is taken to be twice as much as the period doubling of spectral lines

Design issues of optical router for metropolitan optical network (MON) applications

Science.gov (United States)

Wei, Wei; Zeng, QingJi

2001-10-01

The popularity of the Internet has caused the traffic on the Metro Area Network (MAN) to grow drastically every year. It is believed that Wavelength Division Multiplexing (WDM) has become a cornerstone technology in the MAN. Solutions to provide a MAN with high bandwidth, good scalability and easy management are being constantly searched from both IP and WDM. In this paper we firstly propose a metro optical network architecture based on GMPLS--a flexible, highly scalable IP over WDM optical network architecture for the delivery of public network IP services. Two kinds of node including Electronic Label Switching Router (E-LSR) and Optical Router (O-LSR) are involved in this metro optical network architecture. Secondly, we mainly focus on design issues of OR including multi-granularity electro-optical hybrid switching fabrics, intelligent OTU, contro l plane software and etc. And we also discuss some issues such as routing, forwarding and management of OR. Finally, we reach conclusions that OR based on GMPLS and hybrid-switching fabrics is suitable for current multi-services application environment of MON and optimistic for IP traffic transfer.

SNS vil høre om det supplerende materiale giver anledning til/ændrer på konklusionen de tidligere fremsendte risikovurderinger. Zea Majs NK603xMON810. Supplerende materiale til sagen. Modtaget 07-02-2005, deadline 25-02-2005, svar 23-02-2005

DEFF Research Database (Denmark)

Strandberg, Morten Tune

2005-01-01

Brev: Det tilsendte materiale giver ikke anledning til ændringer på konklusionen i tidligere risikovurderinger af MON810xNK603-majs til anden brug end dyrkning. Danmarks Miljøundersøgelser forventer således efter gennemgang af det supplerende materiale til sagen MON810xNK603 fortsat ingen væsentl...

som Ungarn har fremsendt giver anledning til kommentarer eller ændringer i den risikovurdering som Danmark har gennemført i forbindelse med tilladelsen til markedsføring af majslinien MON810. " Zea mays (MON810), Indsigelse fra Ungarn vedr. nye oplysninger der påvirker risikovurderingen. Modtaget 20

DEFF Research Database (Denmark)

Kjellsson, Gøsta; Strandberg, Morten Tune; Damgaard, Christian

2005-01-01

"DMU vurderer at det præsenterede undersøgelsesmateriale fra Ungarn ikke giver nogen videnskabelig velbegrundet formodning om at den ovennævnte MON810-majs udgør en risiko for miljøet. Ungarn har således for nærværende ingen videnskabeligt baseret grund til at forbyde dyrkning og salg af såsæd in...

Monitoring effectiveness of the EU Nitrates Directive Action Programmes. Results of the international MonNO3 workshop in the Netherlands, 11-12 June 2003

NARCIS (Netherlands)

Fraters B; Kovar K; Willems WJ; Stockmarr J; Grant R; LVM

2005-01-01

Dit rapport bevat de bijdragen van de deelnemers aan de MonNO3 workshop, georganiseerd door het RIVM, GEUS en DMU. De workshop is gehouden op 11 en 12 juni 2003 en vond plaats in Den Haag (Scheveningen). Het rapport geeft ook een synthese van deze bijdragen en de workshopdiscussies over de

Precipitation sequences in austenitic Fe-22Cr-21Ni-6Mo-(N) stainless steels

International Nuclear Information System (INIS)

Kim, S.-J.; Lee, T.-H.

1999-01-01

Precipitation sequence of nitrogen containing Fe-22Cr-21Ni-6Mo-N austenitic stainless steel has been investigated after aging at high temperatures, and compared with nitrogen free steel. The σ phases and M 23 C 6 carbides were observed along the grain boundaries as well as in the matrix in both of the solution treated specimens. The M 6 C carbides and chi phase appeared successively in between 3 hours and 24 hours depending on the nitrogen content. Main difference in aging behavior was the precipitation of fine nitrides. Aging for 24 hours and 168 hours of nitrogen containing steel resulted in the formation of fine Cr 2 N and faceted AlN nitrides. The crystallography, structure and morphology were analyzed with analytical electron microscopy. (orig.)

Transcriptomic Analysis of Intestinal Tissues from Two 90-Day Feeding Studies in Rats Using Genetically Modified MON810 Maize Varieties

Directory of Open Access Journals (Sweden)

Jutta Sharbati

2017-12-01

Full Text Available Background: Global as well as specific expression profiles of selected rat tissues were characterized to assess the safety of genetically modified (GM maize MON810 containing the insecticidal protein Cry1Ab. Gene expression was evaluated by use of Next Generation Sequencing (NGS as well as RT-qPCR within rat intestinal tissues based on mandatory 90-day rodent feeding studies. In parallel to two 90-day feeding studies, the transcriptional response of rat tissues was assessed as another endpoint to enhance the mechanistic interpretation of GM feeding studies and/or to facilitate the generation of a targeted hypothesis. Rats received diets containing 33% GM maize (MON810 or near-isogenic control maize. As a site of massive exposure to ingested feed the transcriptomic response of ileal and colonic tissue was profiled via RT-qPCR arrays targeting apoptosis, DNA-damage/repair, unfolded protein response (UPR. For global RNA profiling of rat ileal tissue, we applied NGS.Results: No biological response to the GM-diet was observed in male and in female rat tissues. Transcriptome wide analysis of gene expression by RNA-seq confirmed these findings. Nevertheless, gene ontology (GO analysis clearly associated a set of distinctly regulated transcripts with circadian rhythms. We confirmed differential expression of circadian clock genes using RT-qPCR and immunoassays for selected factors, thereby indicating physiological effects caused by the time point of sampling.Conclusion: Prediction of potential unintended effects of GM-food/feed by transcriptome based profiling of intestinal tissue presents a novel approach to complement classical toxicological testing procedures. Including the detection of alterations in signaling pathways in toxicity testing procedures may enhance the confidence in outcomes of toxicological trials. In this study, no significant GM-related changes in intestinal expression profiles were found in rats fed GM-maize MON810. Relevant

Morphologic and thermophysical characteristics of lava flows southwest of Arsia Mons, Mars

Science.gov (United States)

Crown, David A.; Ramsey, Michael S.

2017-08-01

The morphologic and thermophysical characteristics of part of the extensive lava flow fields southwest of Arsia Mons (22.5-27.5°S, 120-130°W) have been examined using a combination of orbital VNIR and TIR datasets. THEMIS images provide context for the regional geology and record diurnal temperature variability that is diverse and unusual for flow surfaces in such close proximity. CTX images were used to distinguish dominant flow types and assess local age relationships between individual lava flows. CTX and HiRISE images provide detailed information on flow surface textures and document aeolian effects as they reveal fine-grained deposits in many low-lying areas of the flow surfaces as well as small patches of transverse aeolian ridges. Although this region is generally dust-covered and has a lower overall thermal inertia, the THEMIS data indicate subtle spectral variations within the population of lava flows studied. These variations could be due to compositional differences among the flows or related to mixing of flow and aeolian materials. Specific results regarding flow morphology include: a) Two main lava flow types (bright, rugged and dark, smooth as observed in CTX images) dominate the southwest Arsia Mons/NE Daedalia Planum region; b) the bright, rugged flows have knobby, ridged, and/or platy surface textures, commonly have medial channel/levee systems, and may have broad distal lobes; c) the dark, smooth flows extend from distributary systems that consist of combinations of lava channels, lava tubes, and/or sinuous ridges and plateaus; and d) steep-sided, terraced margins, digitate breakout lobes, and smooth-surfaced plateaus along lava channel/tube systems are interpreted as signatures of flow inflation within the dark, smooth flow type. These flows exhibit smoother upper surfaces, are thinner, and have more numerous, smaller lobes, which, along with their the channel-/tube-fed nature, indicate a lower viscosity lava than for the bright, rugged flows

Geologic Mapping of the Olympus Mons Volcano, Mars

Science.gov (United States)

Bleacher, J. E.; Williams, D. A.; Shean, D.; Greeley, R.

2012-01-01

We are in the third year of a three-year Mars Data Analysis Program project to map the morphology of the Olympus Mons volcano, Mars, using ArcGIS by ESRI. The final product of this project is to be a 1:1,000,000-scale geologic map. The scientific questions upon which this mapping project is based include understanding the volcanic development and modification by structural, aeolian, and possibly glacial processes. The project s scientific objectives are based upon preliminary mapping by Bleacher et al. [1] along a approx.80-km-wide north-south swath of the volcano corresponding to High Resolution Stereo Camera (HRSC) image h0037. The preliminary project, which covered approx.20% of the volcano s surface, resulted in several significant findings, including: 1) channel-fed lava flow surfaces are areally more abundant than tube-fed surfaces by a ratio of 5:1, 2) channel-fed flows consistently embay tube-fed flows, 3) lava fans appear to be linked to tube-fed flows, 4) no volcanic vents were identified within the map region, and 5) a Hummocky unit surrounds the summit and is likely a combination of non-channelized flows, dust, ash, and/or frozen volatiles. These results led to the suggestion that the volcano had experienced a transition from long-lived tube-forming eruptions to more sporadic and shorter-lived, channel-forming eruptions, as seen at Hawaiian volcanoes between the tholeiitic shield building phase (Kilauea to Mauna Loa) and alkalic capping phase (Hualalai and Mauna Kea).

Measurement and Estimation of the 99Mo Production Yield by 100Mo(n,2n)99Mo

Science.gov (United States)

Minato, Futoshi; Tsukada, Kazuaki; Sato, Nozomi; Watanabe, Satoshi; Saeki, Hideya; Kawabata, Masako; Hashimoto, Shintaro; Nagai, Yasuki

2017-11-01

We, for the first time, measured the yield of 99Mo, the mother nuclide of 99mTc used in nuclear medicine diagnostic procedures, produced by the 100Mo(n,2n)99Mo reaction with accelerator neutrons. The neutrons with a continuous energy spectrum from the thermal energy up to about 40 MeV were provided by the C(d,n) reaction with 40 MeV deuteron beams. It was proved that the 99Mo yield agrees with that estimated by using the latest data on neutrons from the C(d,n) reaction and the evaluated cross section of the 100Mo(n,2n)99Mo reaction given in the Japanese Evaluated Nuclear Data Library. On the basis of the agreement, a systematic calculation was carried out to search for an optimum condition that enables us to produce as much 99Mo as possible with a good 99Mo/100Mo value from an economical point of view. The calculated 99Mo yield from a 150 g 100MoO3 sample indicated that about 30% of the demand for 99Mo in Japan can be met with a single accelerator capable of 40 MeV, 2 mA deuteron beams. Here, by referring to an existing 18F-fluorodeoxyglucose (FDG) distribution system we assumed that 99mTc radiopharmaceuticals formed after separating 99mTc from 99Mo can be delivered to hospitals from a radiopharmaceutical company within 6 h. The elution of 99mTc from 99Mo twice a day would meet about 50% of the demand for 99Mo.

Økologisk risikovurdering af en genmo-dificeret glyfosat-tolerant raps MON 88302 i anmeldelse til godkendelse vedr. import til markedsføring under Forordning 1829/2003/EF

DEFF Research Database (Denmark)

Kjellsson, Gøsta; Sørensen, Jesper Givskov; Strandberg, Morten Tune

2012-01-01

to be small. Fur-thermore, there are methods to monitor such dispersal of the GMO-plant into cultivated fields and surroundings. Although, not directly an environmental issue, we find that dispersal of the MON 88302 oilseed rape could result in problems for co-existence with non-GMO-cultivation....

Avaliação do monômero residual de resinas acrílicas utilizadas para prótese ocular, polimerizadas convencionalmente e por energia de microondas = Evaluation of residual monomer between conventional and microwave heat-cured acrylic resins used for ocular prostheses

Directory of Open Access Journals (Sweden)

Moroni, Pedro Alexandre

2005-01-01

Full Text Available Este trabalho objetivou comparar a quantidade de monômero residual das resinas acrílicas utilizadas para confecção de prótese ocular, termopolimerizável incolor (grupo controle e Onda-Cryll incolor após a polimerização convencional (MC e com energia de microondas (MW respectivamente. Para o experimento foram confeccionados três corpos-de-prova para cada tipo de resina e período de investigação, num total de 30 corpos-de-prova, os quais foram submetidos a ensaios titulométricos nos períodos de 5, 30 60, 120 e 1. 440 minutos (24 horas após a demuflagem. A resina acrílica termopolimerizável incolor apresentou índice inferiores de concentração de monômero residual em relação à resina acrílica Onda-Cryll incolor. A resina acrílica polimerizada por microondas apresentou baixos indíces de concentração de monômero residual, porém um pouco superiores (até 120 minutos em relação à resina termopolimerizável incolor. Ambos os materiais apresentaram valores numéricos estatisticamente semelhantes de concentração de monômero residual no período de 1440 minutos (24horas. Uma técnica de confecção de prótese ocular através de forno de microondas é exeqüível, pois os acrílicos apresentam concentrações normais de monômero residual após 120 minutos da sua polimerização, em relação ao grupo controle

Memory and Identity in the Emotive Map of Alain Resnais’ Hiroshima Mon Amour (1959

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Jytte Holmqvist

2014-11-01

Full Text Available The focus of this article is Alain Resnais’ representation of collective and individual memory and identity in Hiroshima Mon Amour (1959. The film is based on Marguerite Duras’ script from 1958 and remains faithful to this original text. With partial reference to Giuliana Bruno’s views on imaginary cities and urban cartography, the screened urban space will here be read as an emotive map in which the individual love story between the protagonists unfolds against the backdrop of their almost equally intimate relationship with the historically abused city of Hiroshima. This, in Bruno’s words helps create an affective “map of love” (243 or a “body-city on a tender map” (242. The paper highlights the fluid relationship between the protagonists and their environment, as well as the semi-documentary aspects of a film that establishes an effective dialogue between past and present.

The effect of feeding Bt MON810 maize to pigs for 110 days on intestinal microbiota.

Directory of Open Access Journals (Sweden)

Stefan G Buzoianu

Full Text Available OBJECTIVE: To assess the effects of feeding Bt MON810 maize to pigs for 110 days on the intestinal microbiota. METHODOLOGY/PRINCIPAL FINDINGS: Forty male pigs (∼40 days old were blocked by weight and litter ancestry and assigned to one of four treatments; 1 Isogenic maize-based diet for 110 days (Isogenic; 2 Bt maize-based diet (MON810 for 110 days (Bt; 3 Isogenic maize-based diet for 30 days followed by a Bt maize-based diet for 80 days (Isogenic/Bt; 4 Bt maize-based diet for 30 days followed by an isogenic maize-based diet for 80 days (Bt/Isogenic. Enterobacteriaceae, Lactobacillus and total anaerobes were enumerated in the feces using culture-based methods on days 0, 30, 60 and 100 of the study and in ileal and cecal digesta on day 110. No differences were found between treatments for any of these counts at any time point. The relative abundance of cecal bacteria was also determined using high-throughput 16 S rRNA gene sequencing. No differences were observed in any bacterial taxa between treatments, with the exception of the genus Holdemania which was more abundant in the cecum of pigs fed the isogenic/Bt treatment compared to pigs fed the Bt treatment (0.012 vs 0.003%; P≤0.05. CONCLUSIONS/SIGNIFICANCE: Feeding pigs a Bt maize-based diet for 110 days did not affect counts of any of the culturable bacteria enumerated in the feces, ileum or cecum. Neither did it influence the composition of the cecal microbiota, with the exception of a minor increase in the genus Holdemania. As the role of Holdemania in the intestine is still under investigation and no health abnormalities were observed, this change is not likely to be of clinical significance. These results indicate that feeding Bt maize to pigs in the context of its influence on the porcine intestinal microbiota is safe.

El sueño premonitorio de Moisés Almosnino sobre Yosef Nasí en el Tratado de los sueños (Salónica 1564

Directory of Open Access Journals (Sweden)

Romeu Ferré, Pilar

2004-06-01

Full Text Available Moshe Almosnino and Yosef Nasi did not only share a common political and social context, namely Salónica, Constantinople in the 16th century. They also devoted their time and effort to help the Sephardic people of the Diaspora to which they both belonged. One can say that their work got rewarded as the premonitory dream was fulfilled.Dos personajes famosos, Moisés Almosnino y Yosef Nasí, coincidieron en un espacio geográfico y temporal común (Salónica-Constantinopla a mediados del siglo XVI. Ambos trabajaron desde allí denodadamente en favor del pueblo sefardí en la diáspora. La realización del sueño premonitorio vendría a colmar las expectativas de ambos.

GSC4813-0981 = V921 Mon, a new low-amplitude δ Scuti star with variable amplitude

Science.gov (United States)

Galeev, A.; Bikmaev, I.; Shimansky, V.; Deminova, N.

2014-11-01

GSC 4813-0981 = V921 Mon is a low-amplitude δ Scuti-type variable with an amplitude of 0.018^m-0.027^m in different bands and a period of 48.5 minutes. The fundamental parameters of the atmosphere and physical characteristics, determined from medium-resolution spectra, are: T_{eff}=8700 K, log g=3.95 dex, [M/H]=0, M=1.7 M_{⊙}, R=2.3 R_{⊙}. We performed a long-term analysis of the variations using a ten-year data set of CCD observations (2003-2013) acquired in BVR with the 1.5-m Russian-Turkish telescope (RTT150, TUBITAK National Observatory). A preliminary result is that the amplitude of the variability changes; it was decreasing during 2003-2008, but is now increasing.

Un esbozo de traducción latina de la Reposta ahum papel de Moisés Rafael de Aguilar

Directory of Open Access Journals (Sweden)

Toribio Pérez, Pablo

2013-12-01

Full Text Available This article contains the text and Spanish translation of Johann Christoph Wolf’s (1683-1739 fragmentary draft of a Latin translation of portions of Moses Raphael d’Aguilar’s (d. 1679 Reposta ahum Papel. Wolf’s partial translation is preserved in Hamburg, Staats- und Universitätsbibliothek, Theol. 1831. The original Portuguese text is an anti-Christian work which was well known in a number of Protestant, anti-Trinitarian and atheistic circles during the eighteenth century. Its diffusion has been studied by Martin Mulsow; however, the text itself still lacks an edition.Se ofrece el texto y la traducción castellana del esbozo de traducción latina de la Reposta ahum papel de Moisés Rafael de Aguilar (m. 1679 que llevó a cabo Johann Christoph Wolf (1683-1739. El documento autógrafo de este intento de traducción se conserva en Hamburgo, Staats- und Universitätsbibliothek, Theol. 1831. El texto portugués original es un escrito anticristiano que conoció una considerable difusión en diversos círculos protestantes, antitrinitarios y ateos durante el siglo XVIII. Dicha difusión ha sido estudiada por Martin Mulsow; sin embargo, el texto en sí todavía carece de edición.

Arsia Mons by Day and Night

Science.gov (United States)

2004-01-01

[figure removed for brevity, see original site] Released 22 June 2004 This pair of images shows part of Arsia Mons. Day/Night Infrared Pairs The image pairs presented focus on a single surface feature as seen in both the daytime and nighttime by the infrared THEMIS camera. The nighttime image (right) has been rotated 180 degrees to place north at the top. Infrared image interpretation Daytime: Infrared images taken during the daytime exhibit both the morphological and thermophysical properties of the surface of Mars. Morphologic details are visible due to the effect of sun-facing slopes receiving more energy than antisun-facing slopes. This creates a warm (bright) slope and cool (dark) slope appearance that mimics the light and shadows of a visible wavelength image. Thermophysical properties are seen in that dust heats up more quickly than rocks. Thus dusty areas are bright and rocky areas are dark. Nighttime: Infrared images taken during the nighttime exhibit only the thermophysical properties of the surface of Mars. The effect of sun-facing versus non-sun-facing energy dissipates quickly at night. Thermophysical effects dominate as different surfaces cool at different rates through the nighttime hours. Rocks cool slowly, and are therefore relatively bright at night (remember that rocks are dark during the day). Dust and other fine grained materials cool very quickly and are dark in nighttime infrared images. Image information: IR instrument. Latitude -19.6, Longitude 241.9 East (118.1 West). 100 meter/pixel resolution. Note: this THEMIS visual image has not been radiometrically nor geometrically calibrated for this preliminary release. An empirical correction has been performed to remove instrumental effects. A linear shift has been applied in the cross-track and down-track direction to approximate spacecraft and planetary motion. Fully calibrated and geometrically projected images will be released through the Planetary Data System in accordance with Project

Sabates per a na Catherina : Esclaves monàstiques al Monestir de Sant Antoni i Santa Clara de Barcelona (1350-1495)

OpenAIRE

Turull Pibernat, Emi

2015-01-01

En el marc de la ciutat de Barcelona, els drets de la dona a la baixa edat mitjana minvaven i havien fet una involució afavorida per una creixent misogínia. Així mateix, la ciutat havia esdevingut un indret rellevant com a mercat d'esclaus i la propietat d'esclaus i esclaves s'estenia de manera natural per tots els estaments de la societat, sense que l'Església la deslegitimés. Veurem què significava ser esclava i comprovarem la seva presència a les institucions monàstiques femenines de Barce...

Toponymie : un héritage précieux

OpenAIRE

Crivelli, Ruggero

2013-01-01

Une montagne de mots (Olivone, Tessin, Suisse) En 2008, Mauro Corona publie un livre dont le titre était I fantasmi di pietra (les fantômes de pierre). Il y raconte des histoires de vie de son village, Erto, dans la région du Vajont, détruit par l’alluvion de 1963 et pratiquement abandonné depuis. En prenant prétexte d’une visite des lieux de son enfance, dont il ne reste plus que les ruines des maisons et des places, l’auteur s’arrête de coin en coin et raconte des morceaux d’une vie passée ...

Relação dos sistemas de monção com as variabilidades tropical interanual e multi-decenal Relations of the monsoon systems to the tropical multi-decadal and interannual variabilities

Directory of Open Access Journals (Sweden)

Sâmia Regina Garcia

2009-03-01

Full Text Available A variabilidade da circulação tropical, com ênfase nos sistemas monçônicos, é examinada usando diversas variáveis para o período de 1948-1999. A componente monçônica do potencial de velocidade em 200 hPa (χ-transiente, o desvio da média anual do desvio da média zonal, é o parâmetro chave usado para obter os modos monçônicos. A análise de Funções Ortogonais Empíricas (EOF do χ-transiente fornece dois modos separados. O primeiro modo descreve a variabilidade multi-decenal dos sistemas monçônicos da América do Sul e do Pacífico oeste. Esse modo, chamado monçônico multi-decenal (MMD, ocorre por todo o ano e contém a variabilidade multi-decenal relacionada à dinâmica da Oscilação Decenal do Pacífico (ODP. O segundo modo descreve as variações interanuais opostas entre a Ásia, África e oceano Índico e a região do oeste dos Estados Unidos, México e Pacífico leste. Esse modo, chamado modo interanual (MIA apresenta algumas similaridades com o modo tropical interanual El Niño - Oscilação Sul. Alguns aspectos desses modos, incluindo sua circulação e características termodinâmicas são discutidas aqui. Finalmente, índices baseados nos padrões das configurações espaciais desses modos são construídos. A eficiência desses índices para fins de monitoramento é analisada. Logo, trata-se de um novo aspecto não proposto em trabalhos anteriores.Tropical circulation variability, with emphasis on the monsoon systems is examined using several variables for the 1948-1999 period. The monsoon component in the 200 hPa velocity potential (transient-χ, the deviation from the annual mean of the zonal deviation field, is the key parameter used here to obtain the monsoon modes. The Empirical Orthogonal Function (EOF analysis of the transient-χ yields two separate modes. The first mode describes the multi-decadal variability of the monsoon systems in South America and in the western Pacific. This mode, called the multi

Paleo-environmental Setting of the Murray Formation of Aeolis Mons, Gale Crater, Mars, as Explored by the Curiosity Rover

Science.gov (United States)

Lewis, K. W.; Fedo, C.; Grotzinger, J. P.; Gupta, S.; Stein, N.; Rivera-Hernandez, F.; Watkins, J. A.; Banham, S.; Edgett, K. S.; Minitti, M. E.; Schieber, J.; Edgar, L. A.; Siebach, K. L.; Stack, K.; Newsom, H. E.; House, C. H.; Sumner, D. Y.; Vasavada, A. R.

2017-12-01

Since landing, the Mars Science Laboratory Curiosity rover climbed 300 meters in elevation from the floor of north Gale crater up the lower northwest flank of Aeolis Mons ("Mount Sharp"). Nearly 200 meters of this ascent was accomplished in the 1.5 years alone, as the rover was driven up-section through the sedimentary rocks of the informally designated "Murray" formation. This unit comprises a large fraction of the lower strata of Mt. Sharp along the rover traverse. Our exploration of the Murray formation reveals a diverse suite of fine-grained facies. Grain sizes range from finer grains than can be resolved by the MAHLI imager (particles bearing Vera Rubin Ridge, continues to reveal the complex and long-lived depositional history of the Gale crater basin.

Parole et silence pour l’expression de l’éthique dans La mort est mon métier de Robert Merle

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María Badiola Dorronsoro

2015-11-01

Full Text Available Thanks to a daring and original exercise of focusing the narrative in first person, Robert Merle makes a historical Nazi the hero and narrator of his novel La mort est mon métier. Adding to this fact a careful choice of what is said and what is omitted, the author shows that the “final solution to the Jewish problem” by Hitler was not a massacre organized by some bloodthirsty or revengeful individuals, but a «hard task» accomplished by a group of de¬humanized beings for whom the honor –and morals– consisted of total dedication to blind obe¬dience to their superiors.

Perfil audiométrico e de emissões otoacústicas evocadas por produto de distorção em gestores de trânsito expostos a monóxido de carbono e ruído

Directory of Open Access Journals (Sweden)

Soraya de Carvalho Rocha

2013-04-01

Full Text Available OBJETIVO: avaliar o perfil audiométrico e de emissões otoacústicas evocadas por produto de distorção em gestores de trânsito, expostos a monóxido de carbono e ruído, bem como constatar a presença de ambos agentes nos postos de trabalho. MÉTODO:estudo transversal, descritivo, com 37 gestores do trânsito, submetidos a anamnese, meatoscopia, audiometria tonal e emissões otoacústicas, distribuídos em: G1, composto por 18 indivíduos sem histórico de exposição concomitante a monóxido de carbono e ruído; e, G2, formado por 19 trabalhadores expostos simultaneamente aos dois agentes. Para pesquisa da presença dos agentes no ambiente foram utilizadas audiodosímetrias e avaliações de curta duração com medidor instantâneo. As variáveis de anamnese foram analisadas segundo o teste t Student e Mann-Whitney. Para as medidas de otoemissões acústicas e de limiares tonais utilizou-se testes de qui-quadrado (χ2 ou exato de Fisher e dos postos sinalizados de Wilcoxon com significância de 5%. RESULTADOS: foi constatada presença de monóxido de carbono e ruído durante a atividade dos trabalhadores. Não foi observada diferença significante na idade e tempo de função. O G2 obteve média de limiares tonais maior que G1, para orelha direita, em 1KHz (p=0,050 e para orelha esquerda em 3KHz (p=0,016 e 4KHz (p=0,028; e, comparados os limiares tonais alterados G2 apresentou diferença maior em 3KHz na orelha esquerda (p=0,003. Nas emissões otoacústicas, G2 apresentou maior ausência de respostas que G1 em 2.730Hz e 3.218Hz (p=0.016 para orelha direita. CONCLUSÃO: trabalhadores expostos a monóxido de carbono e ruído apresentaram piores resultados audiométricos e nas emissões otoacústicas quando comparado ao grupo de não expostos.

Stages of in vitro phagocytosis of Plasmodium falciparum-infected erythrocytes by human monocytes Estágios da fagocitose in vitro por monócitos humanos de eritrócitos infectados por Plasmodium falciparum

Directory of Open Access Journals (Sweden)

Maria Imaculada Muniz-Junqueira

2009-04-01

Full Text Available Monocytes/macrophages play a critical role in the defense mechanisms against malaria parasites, and are the main cells responsible for the elimination of malaria parasites from the blood circulation. We carried out a microscope-aided evaluation of the stages of in vitro phagocytosis of Plasmodium falciparum-infected erythrocytes, by human monocytes. These cells were obtained from healthy adult individuals by means of centrifugation through a cushion of Percoll density medium and were incubated with erythrocytes infected with Plasmodium falciparum that had previously been incubated with a pool of anti-plasmodial immune serum. We described the stages of phagocytosis, starting from adherence of infected erythrocytes to the phagocyte membrane and ending with their destruction within the phagolisosomes of the monocytes. We observed that the different erythrocytic forms of the parasite were ingested by monocytes, and that the process of phagocytosis may be completed in around 30 minutes. Furthermore, we showed that phagocytosis may occur continuously, such that different phases of the process were observed in the same phagocyte.Monócitos/macrófagos desempenham uma função crítica nos mecanismos de defesa antiplasmódio e constituem as principais células responsáveis pela eliminação das formas eritrocitárias do plasmódio da circulação sangüínea. Realizamos uma avaliação microscópica dos estágios da fagocitose in vitro de eritrócitos infectados por Plasmodium falciparum por monócitos humanos. Essas células foram obtidas de indivíduos adultos sadios por centrifugação em Percoll e incubadas com eritrócitos infectados por Plasmodium falciparum previamente incubados com um pool de soro imune contra plasmódio. Descrevemos os estágios da fagocitose, desde a aderência dos eritrócitos infectados até sua destruição nos fagolisossomas dos monócitos. Observou-se que eritrócitos infectados por todos os diferentes est

AmI and deployment considerations in AAL services provision for elderly independent living: the MonAMI project.

Science.gov (United States)

Falcó, Jorge L; Vaquerizo, Esteban; Lain, Luis; Artigas, Jose Ignacio; Ibarz, Alejandro

2013-07-12

The MonAMI project aims to investigate the feasibility of the deployment of open platforms for Ambient Assisted Living (AAL) services provision based on Ambient Intelligence (AmI) and to test user acceptance and the usability of the services. Services were designed to provide support in the areas of environmental control, security, well-being and leisure. These services were installed and evaluated in a Spanish geriatric residence. The participants included elderly persons with disabilities, nursing home care givers and informal carers. The concept of the open platform proved to be satisfactory for the provision of the services in a context aware framework. Furthermore, the usability of the technology was viewed positively and the overall results indicate that this system has the potential to prolong independent living at home for elderly people with disabilities. Deployment was proven successful and awareness of open-platform AAL service delivery was raised in local communities throughout Europe.

AmI and Deployment Considerations in AAL Services Provision for Elderly Independent Living: The MonAMI Project

Directory of Open Access Journals (Sweden)

Alejandro Ibarz

2013-07-01

Full Text Available The MonAMI project aims to investigate the feasibility of the deployment of open platforms for Ambient Assisted Living (AAL services provision based on Ambient Intelligence (AmI and to test user acceptance and the usability of the services. Services were designed to provide support in the areas of environmental control, security, well-being and leisure. These services were installed and evaluated in a Spanish geriatric residence. The participants included elderly persons with disabilities, nursing home care givers and informal carers. The concept of the open platform proved to be satisfactory for the provision of the services in a context aware framework. Furthermore, the usability of the technology was viewed positively and the overall results indicate that this system has the potential to prolong independent living at home for elderly people with disabilities. Deployment was proven successful and awareness of open-platform AAL service delivery was raised in local communities throughout Europe.

El lugar del padre primordial en Moisés y la religión monoteísta: Algunas conclusiones The Place Of The Primordial Father In Moses And Monotheism: Some Conclusions

Directory of Open Access Journals (Sweden)

Laura Edith Raffaini

2008-12-01

Full Text Available En Moisés y la religión monoteísta Freud desarrolla su última versión del padre. En este trabajo, analizo el lugar que ocupa el padre primordial de Tótem y tabú a partir de dicha versión. Presento, asimismo, un movimiento teórico fundamental en la teoría freudiana sobre el padre: el pasaje del padre primordial a la religión del padre como producto de la neurosis.In "Moses and Monotheism" Freud's ultimate version of the father is described. In this paper, the place the primordial father in "Totem und Tabu" occupies is established based on such version. The transition from the primordial father to the religion of the father as a neurosis product is analysed.

Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI

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Margison Geoffrey P

2006-03-01

Full Text Available Abstract Background A number of gene therapy applications would benefit from vectors capable of expressing multiple genes. In this study we explored the feasibility and efficiency of expressing two or three transgenes in HIV-1 based lentiviral vector. Bicistronic and tricistronic self-inactivating lentiviral vectors were constructed employing the internal ribosomal entry site (IRES sequence of encephalomyocarditis virus (EMCV and/or foot-and-mouth disease virus (FMDV cleavage factor 2A. We employed enhanced green fluorescent protein (eGFP, O6-methylguanine-DNA-methyltransferase (MGMT, and homeobox transcription factor HOXB4 as model genes and their expression was detected by appropriate methods including fluorescence microscopy, flow cytometry, immunocytochemistry, biochemical assay, and western blotting. Results All the multigene vectors produced high titer virus and were able to simultaneously express two or three transgenes in transduced cells. However, the level of expression of individual transgenes varied depending on: the transgene itself; its position within the construct; the total number of transgenes expressed; the strategy used for multigene expression and the average copy number of pro-viral insertions. Notably, at limiting MOI, the expression of eGFP in a bicistronic vector based on 2A was ~4 times greater than that of an IRES based vector. Conclusion The small and efficient 2A sequence can be used alone or in combination with an IRES for the construction of multicistronic lentiviral vectors which can express encoded transgenes at functionally relevant levels in cells containing an average of one pro-viral insert.

Photometric Investigation of Novae T Pyx, BT Mon and V574 Pup at Quiescence by using the 2.4-m Thai National Telescope

Science.gov (United States)

Thipboon, Ritthichai; Kaewrakmuk, Metichai; Surina, Farung; Sanguansak, Nuanwan

2017-09-01

Recurrent novae (RNe) are novae with multiple recorded outbursts powered by a thermonuclear runaway. The outburst occurs on the surface of the white dwarf which accompanies with a late type main-sequence or giant secondary star transferring material onto the white dwarf primary star. They resemble classical novae (CNe) outbursts but only RNe has more than one recorded outbursts. RNe play an important role as one of the suspected progenitor systems of Type Ia supernovae (SNe) which are used as primary distance indicators in cosmology. Thus, it is important to investigate the outburst type of CNe and RNe and finally ascertain the population of objects that might ultimately be candidates for Type Ia SNe explosions. The proposal that RNe occupy a region separated from CNe in an outburst amplitude versus speed class diagram was adopted. Since the low amplitude results from the existence of an evolved secondary and/or high mass transfer rate in the quiescent system, RNe candidates should accordingly have low amplitude. We selected 3 preliminary targets including T Pyx, BT Mon and V574 Pup. Their amplitudes are not that low but the lowest amplitude that can be observed with Thai National Telescope (TNT). We obtained their magnitudes at quiescence using ULTRASPEC camera on the 2.4-m TNT. The positions of three targets on optical and near-infrared color-magnitude diagrams suggest that all three should have main-sequence secondary stars. This is true for T Pyx, whose secondary star has been confirmed its spectroscopy to be a main-sequence star, but not yet confirmed for BT Mon and V574 Pup.

Pokémon Go and augmented virtual reality games: a cautionary commentary for parents and pediatricians.

Science.gov (United States)

Serino, Maeve; Cordrey, Kyla; McLaughlin, Laura; Milanaik, Ruth L

2016-10-01

The recent release of Pokémon Go has ushered in a new set of challenges for parents and pediatricians, highlighting the importance of parents setting guidelines for video game use with their children. Within 1 week of its launch, the game attracted over 65 million users, many of whom are young children. Despite the potential benefits of the game described in our article, this location-based game format poses specific threats to the safety and physical wellbeing of children. Reports have discussed both the benefits and adverse effects of this extremely popular video game. Benefits include increased exercise, socialization, and outdoor activity. Negative effects include increased risk of injury, abduction, trespassing, violence, and cost. Pediatricians play a key role in counseling parents and children about safety precautions and setting appropriate limits for impressionable youth. Parents and pediatricians should be aware of this new and remarkably popular game that appeals to a wide variety of individuals. To protect children from injury, predators, and inappropriate situations, parents and pediatricians must regulate children's participation in this game and maintain vigilance for potentially dangerous circumstances.

Paranoid, moi?

DEFF Research Database (Denmark)

Pedersen, Peter Ole; Stephensen, Jan Løhmann

2013-01-01

The authors research the ways in which surveillance discourse and studies on surveillance phenomena manifest itself in mainstream documentary filmmaking. The subject of this critical case study is David Bond’s Erasing David (2010), a hybrid documentary which aesthetics and conceptual roots are cl...

Paranoid, moi?

DEFF Research Database (Denmark)

Pedersen, Peter Ole; Løhmann Stephensen, Jan

2010-01-01

The article discusses the relationship between the subject of surveillance and documentary film. As its main example, it uses David Bonds Erasing David from 2009. The genre-specific and film historic aspects of this documentary is analysed and in a further perspective it serves as the point...... of departure for a more general theoretical discussion of surveillance. Through the treatment of its content and the conceptual framework, Bonds film place itself within what could appropriately be termed the “popular cultural documentary”. What characterises this part of the genre is a critical approach...... film analytical approaches based on Moore’s 1989 debut Roger & Me is used evaluate the aesthetic and conceptual coherence in Bonds work.     Following this, a three-part taxonomy for the analytical and normative understand of the surveillance phenomenon and its socio-cultural and political implications...

Perupaan dan Sinkronisasi Artefak Percandian Batujaya di Karawang, Jawa Barat dengan Borobudur di Jawa Tengah dan Mon-Dwarawati di Thailand

Directory of Open Access Journals (Sweden)

Nuning Damayanti

2014-10-01

Full Text Available Percandian Batujaya adalah sebuah kompleks sisa-sisa percandian Budha kuno yang terletak di Kecamatan Batujaya dan Kecamatan Pakisjaya, Kabupaten Karawang, Provinsi Jawa Barat. Adanya dua fase pembangunan pada Batujaya membuka kemungkinan terhadap interpretasi akan adanya gaya-gaya perupaan yang berbeda pada percandian Batujaya. Berdasarkan hasil penelitian, dapat ditarik kesimpulan bahwa mazhab Budha yang diterapkan pada kompleks percandian Batujaya adalah mazhab Mahayana, dicirikan dengan keberadaan votive tablet dengan perupaan yang menggambarkan sosok-sosok bodhisattva dan Budha. Perbandingan gaya visual dengan artefak-artefak yang berasal dari periode Mon-Dwarawati di wilayah Thailand dan artefak Borobudur di Jawa Tengah menunjukkan bahwa artefak Batujaya cenderung memiliki gaya naturalis yang lebih serupa dengan Dwarawati terutama pada profil wajah dibandingkan gaya stilasi Borobudur yang lebih dekat secara geografis. Terdapat ciri khas pada arca Batujaya yaitu cenderung memiliki bentuk mata yang didistorsi menjadi lebih besar dan terkesan membelalak, serta hidung yang lebar. Kemungkinan hal ini didasari bentuk fisik masyarakat lokal atau pemikiran ideal lokal mengenai fisik yang sempurna.Kata kunci: arca; Batujaya; Budha Mahayana; gaya perupaan; votive tablet.Batujaya enshrinement complex is a remnant of ancient Buddhist monument, located in Kecamatan Batujaya and Kecamatan Pakisjaya, Karawang, West Java. The two development phases of Batujaya would open the possibility of different interpretations of visual style in Batujaya. Based on these results, it could be concluded that the Buddhist sect worshipped in Batujaya was Mahayana sect, characterized by votive tablets depicting bodhisattva and Budha. Comparison of visual style with the artifacts dating from Mon-Dvaravati period in Thailand region and Borobudur in Central Java indicated that Batujaya artifacts tend to have more naturalistic style similar to Dwarawati primarily onfacial

Conciencia hispana y tradición monástica en la Vita Fructuosi

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Rodríguez de la Peña, Alejandro

2007-12-01

Full Text Available The author of Vita Fructuosi, probably a monk follower of Saint Fructuosus of Braga in the area of Gallaecia, shows in this biography an evident sense of rooting in the monastic Tradition, specially in the Egyptianeastern one, and also he declares a strong Roman-Catholic and Hispanic conscience. As the highest expression of it, he presents Saint Fructuosus with the same merits of the Egyptian monks and, joined to Saint Isidorus of Seville, as a light for Spain, for the Western and for the whole Catholic Church: they both are two causes of glory for a Visigothic Spain which fells herself as Roman and Catholic.El autor de la Vita Fructuosi, al parecer un monje discípulo de San Fructuoso de Braga en el área de Gallaecia, muestra en esta biografía un claro sentido de arraigo en la Tradición monástica, especialmente egipcio-oriental, y manifiesta una fuerte conciencia romano-católica e hispana. Como máxima expresión de todo ello, presenta a San Fructuoso a la altura de los méritos de los monjes egipcios y, junto con San Isidoro de Sevilla, como una lumbrera de Hispania, del Occidente y de toda la Iglesia Católica: ambos son dos motivos de gloria de la Hispania visigótica que se siente romana y católica.

Estrategias territoriales de un poder monástico en la Galicia medieval: Celanova (siglos X-XII

Directory of Open Access Journals (Sweden)

José Carlos SÁNCHEZ PARDO

2011-02-01

Full Text Available Se pretende afrontar un tema tradicional en la historiografía medieval española, como son los dominios monásticos, desde la perspectiva menos explorada de las estrategias espaciales que la reciente expansión del uso de los Sistemas de Información Geográfica ha facilitado. De esta manera, a través del caso gallego del monasterio de Celanova entre los siglos X y XII, observamos la complejidad que se esconde tras la planificación de la ubicación de uno de estos centros de poder así como la variedad y flexibilidad de tácticas empleadas en su proceso de crecimiento. Todo ello no solo enfatiza el conocido alto grado de conocimiento del entorno de los poderes señoriales entre finales de la Alta y Plena Edad Media, sino que también revela la importancia que dichos grupos daban a las estrategias espaciales en relación con la estructura preexistente de poblamiento y el papel que estas jugaron en el proceso de feudalización del noroeste peninsular.

Career choices and global health engagement: 24-year follow-up of U.S. participants in the Indiana University-Moi University elective.

Science.gov (United States)

Umoren, Rachel A; Gardner, Adrian; Stone, Geren S; Helphinstine, Jill; Machogu, Emily P; Huskins, Jordan C; Johnson, Cynthia S; Ayuo, Paul O; Mining, Simeon; Litzelman, Debra K

2015-12-01

Global health experiences evoke a profound awareness of cultural differences, inspire learners to prioritize professional values, and provide a lens for addressing global health care challenges. This study compares the long-term career and practice choices of participants in a 2-month Indiana University-Moi University, Kenya elective from 1989-2013 with those of a control group. Global health elective (GHE) participants and a random sample of alumni without GHE experience were surveyed on their clinical practice, public health and global health activities. Responses from 176 former participants were compared with a control group of 177 alumni. GHE participants were more likely than similar controls to provide care to underserved U.S. populations (p=0.037), spend time in global health, public health, and public policy activities (p=0.005) and be involved in global health advocacy (p=0.001). Using multivariable analysis, GHE participants were more likely to be generalists (p<0.05), report that healthcare costs influenced medical decision-making (p<0.05), and provide healthcare outside the U.S. for ≥1 week/year (p<0.001). Many years out of training, GHE participants were more likely to be generalists working with underserved populations, to be cost-conscious in their healthcare decision-making, and to be involved in global health, public health or public policy. With the primary care provider shortage and need for greater awareness among providers of healthcare costs, our study shows that that global health experiences may yield broader benefits to the U.S. medical system. Copyright © 2015 Elsevier Inc. All rights reserved.

Au ban de la société, à la frontière de l’Amérique : les sorcières et les marginaux dans Moi, Tituba sorcière… de Maryse Condé

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Maryse Sullivan

2017-05-01

Full Text Available Dans cet article, nous étudions la figure de la sorcière dans Moi, Tituba sorcière… de Maryse Condé afin de voir comment elle dialogue avec les discours postcoloniaux et féministes de l’époque. Nous analysons d’abord l’intertextualité construit dans le roman avec la pièce d’Arthur Miller Les sorcières de Salem en regardant comment Condé transforme les événements qui ont eu lieu à Salem en 1692 et comment elle réhabilite le personnage de Tituba. Nous nous penchons ensuite sur la figure de la sorcière et des marginaux dans le texte en vue de comprendre sa construction protéiforme et ses points de contact avec les discours ambiants.

Økologisk risikovurdering af gen-modificeret majs-krydsning: 1507 x 59122 x MON810 x NK603 i anmeldelse vedr. markedsføring under Forordning 1829/2003/EF

DEFF Research Database (Denmark)

Kjellsson, Gøsta; Sørensen, Jesper Givskov; Damgaard, Christian

2012-01-01

DCE’s konklusioner vedr. den økologiske risikovurdering af den genmodificerede 1507x59122xMON810xNK603-majs i Danmark Den genmodificerede fire-stakkede majskrydsning adskiller sig fra konven-tionelle majs ved at have indsat gener der gør planterne tolerante over for herbiciderne glufosinat-ammonium...... for import and processing only, will have little or no adverse environmental consequences. In case of accidental mixing and/or dispersal of GMO-seed leading to cultivation of the GMO, DCE suggests that case-specific environ-mental monitoring is needed for detection of possible adverse effects on insect...

Duean sip, théâtre de l’ethnorégionalisme sud. Les nomades de la mer et le cycle rituel du dixième mois dans la province de Phang Nga (sud de la Thaïlande)

OpenAIRE

Ferrari, Olivier

2013-01-01

La cérémonie bouddhique du dixième mois lunaire, connue comme la fête des morts et des revenants, revêt dans la région de Phang Nga, au sud de la Thaïlande une importance et un rôle qui vont bien au-delà de sa signification religieuse. Il s’agit en effet d’un complexe rituel qui, en s’emboîtant avec les cérémonies du festival végétarien des Sino-Thaïs et avec d’autres cérémonies propres aux nomades de la mer (Moken, Moklen et Urak Lawoi), met en scène les fondements des relations interethniqu...

Efeitos da temperatura e do tipo de iniciador na redução do teor de monômero residual durante reações de copolimerização em emulsão Effects of temperature and type of initiators on the reduction of residual monomer content in emulsion copolymerization reactions

Directory of Open Access Journals (Sweden)

Wilson H. Hirota

2004-03-01

Full Text Available Reduzir o teor de monômero residual é uma preocupação de qualquer produtor de polímeros, pois produtos sem, ou com teores muito baixos de monômero residual, apresentam um apelo comercial diferenciado. Neste trabalho são apresentadas e testadas experimentalmente diversas estratégias para reduzir o teor de monômero residual de copolímeros estireno/acrilato de butila produzidos em reações semicontínuas de polimerização em emulsão, que são amplamente utilizados nas indústrias de papel e tintas. Estas estratégias envolvem a adição contínua de iniciador e/ou o aumento da temperatura do reator durante a última etapa da reação, além da adição de um agente redutor e/ou de um iniciador solúvel na fase orgânica. Verificou-se que a combinação adequada de diferentes técnicas pode levar a uma redução significativa no teor residual de monômeros no látex.Reducing the residual monomer content is a major concern of every polymer producer, as products with no, or very low levels of residual monomer have a marked commercial appeal. Styrene / butyl acrylate copolymers produced in emulsion polymerization reactions are widely applied in paper and paint industries. In this work, several strategies to reduce the residual monomer content of styrene and butyl acrylate copolymers produced in semicontinuous emulsion polymerization reactions are presented and tested. These strategies involve the continuous addition of initiator, increasing the reaction temperature during the last stage of the reaction, and adding a reducing agent or an initiator that is soluble in the organic phase at this last stage. The adequate combination of some of these techniques may result in a significant reduction of the residual monomer content in the final latex.

La forma de gobierno en la Constitución de Cádiz : reflexiones sobre la configuración de la jefatura del estado monárquica

Directory of Open Access Journals (Sweden)

Remedio Sánchez Ferriz

2012-01-01

Full Text Available A partir de las circunstancias históricas de las Cortes de Cádiz y de los precedentes de la monarquía española, el artículo analiza la posición de la Jefatura del Estado monárquica en la Constitución de 1812 caracterizada como una «Monarquía moderada» basada en los principios estructurales de soberanía nacional y división de poderes que determinan la configuración del Rey como poder constituido en la nueva forma de gobierno. La afirmación de la soberanía nacional impregna el conjunto del texto constitucional sin perjuicio de que coexista retóricamente con la antigua legitimidad monárquica. Por otra parte, la división de poderes supone la distinción entre la titularidad de la soberanía y su ejercicio por los poderes constituidos, considerándose al monarca el «depositario» del poder ejecutivo frente a unas Cortes que representan a la Nación titular de la soberanía y que, como tales, participan decisivamente en el ejercicio de sus funciones. El alcance de las amplias facultades atribuidas al Rey queda delimitado con las numerosas restricciones que se le imponen en un sistema de rígida separación de poderes. La «Monarquía moderada» que en Cádiz se proclama no es una simple variante de las monarquías limitadas europeas basadas en el principio monárquico sino una forma de gobierno articulada sobre la soberanía nacional y una distribución de las funciones estatales que limita la autoridad —constituida, que no soberana— del Ejecutivo monárquico. Aunque la Constitución de Cádiz atribuyó al Rey no sólo los poderes propios de un Jefe de Gobierno sino también los que la posterior evolución de los Estados monárquicos ha acabado atribuyendo al Rey como Jefe del Estado con un perfil autónomo del poder ejecutivo, no fue posible dar en Cádiz ese paso hacia una Monarquía parlamentaria en la que el Rey abandone en manos de un Gobierno sujeto en exclusiva a la confianza parlamentaria la función de dirección pol

771 Moi Univer

African Journals Online (AJOL)

USER

2015-09-21

Sep 21, 2015 ... and landfills, reuse and recycling of solid waste, willingness to pay for waste disposal, and enhanced good rapport ... of air, soil, water, clogging of drains and creation of ... due to lack of knowledge and awareness about SWM.

From urban planning and emergency training to Pokémon Go: applications of virtual reality GIS (VRGIS) and augmented reality GIS (ARGIS) in personal, public and environmental health.

Science.gov (United States)

Kamel Boulos, Maged N; Lu, Zhihan; Guerrero, Paul; Jennett, Charlene; Steed, Anthony

2017-02-20

The latest generation of virtual and mixed reality hardware has rekindled interest in virtual reality GIS (VRGIS) and augmented reality GIS (ARGIS) applications in health, and opened up new and exciting opportunities and possibilities for using these technologies in the personal and public health arenas. From smart urban planning and emergency training to Pokémon Go, this article offers a snapshot of some of the most remarkable VRGIS and ARGIS solutions for tackling public and environmental health problems, and bringing about safer and healthier living options to individuals and communities. The article also covers the main technical foundations and issues underpinning these solutions.

From urban planning and emergency training to Pokémon Go: applications of virtual reality GIS (VRGIS and augmented reality GIS (ARGIS in personal, public and environmental health

Directory of Open Access Journals (Sweden)

Maged N. Kamel Boulos

2017-02-01

Full Text Available Abstract The latest generation of virtual and mixed reality hardware has rekindled interest in virtual reality GIS (VRGIS and augmented reality GIS (ARGIS applications in health, and opened up new and exciting opportunities and possibilities for using these technologies in the personal and public health arenas. From smart urban planning and emergency training to Pokémon Go, this article offers a snapshot of some of the most remarkable VRGIS and ARGIS solutions for tackling public and environmental health problems, and bringing about safer and healthier living options to individuals and communities. The article also covers the main technical foundations and issues underpinning these solutions.

Évaluation d'un programme de formation professionnelle pour ...

International Development Research Centre (IDRC) Digital Library (Canada)

28 avr. 2016 ... Regarder un documentaire inspirant (en anglais) racontant le quotidien de plusieurs participantes au programme; Détails additionnels sur le programme Mulheres Mil (en anglais); Lire le rapport technique final Mulheres Mil Impact Assessment: final technical report (PDF, 50 Mo). Photo (à droite) : Niagara ...

Infarto do miocárdio e acidente vascular cerebral associados à alta temperatura e monóxido de carbono em área metropolitana do sudeste do Brasil Miocardic infarcts and cerebral-vascular accidents associated with high temperature and carbon monoxide in an metropolitan area of Southeastern Brazil

Directory of Open Access Journals (Sweden)

Davi Rumel

1993-02-01

Full Text Available Muito se tem publicado e discutido acerca de fatores de risco ligados a estilo de vida e a fatores hereditários em Acidente Vascular Cerebral (AVC e Infarto do Miocárdio (IM. Porém o estudo da influência de fatores ambientais como poluição por monóxido de carbono e temperatura na determinação nas ocorrências dessas patologias ainda é pouco discutido em nosso meio. Visando preencher esta lacuna, foi verificada a associação existente entre os valores de temperaturas máximas diárias e valores médio e máximo diários de monóxido de carbono e AVC e IM no Município de São Paulo, SP (Brasil. Foi coletada uma série histórica do número de casos novos de AVC e IM atendidos em Pronto Socorro de um hospital de clínicas e valores de temperatura e monóxido de carbono. Conclui-se que das internações anuais por IM, 2,1% são devidos à poluição atmosférica e 4,9% a altas temperaturas. Das internações anuais por AVC, 2,8% são devidas a altas temperaturas. Não foi identificado associação entre monóxido de carbono e AVC.Many studies have been published about the relationship between life style and genetic risk factors and stroke and heart attack, but there have been few about the relationship between atmospheric pollution, specifically with carbon monoxide, and temperature and stroke and heart attack. With a view to filling this gap the relationship between values of carbon monoxide concentration in the air, maximum and average by day, and maximum temperature by day and the number of new cases of CVA and IM admitted as emergencies at the biggest hospital complex of S. Paulo city was analysed. If was concluded, by the use of multivariable regression analysis, that 2.1% and 4.9% of heart attack admissions were due to carbon monoxide air pollution and high temperature, respectively. 2.8% of stroke admissions were due high temperature. Stroke and carbon monoxide were not associated in this population.

Hverdagslivet, sproget og kærligheden

DEFF Research Database (Denmark)

Madsen, Peter

2006-01-01

Anmelse af Toril Mois bog Ibsens modernisme. Bemærker bl.a. hvordan Mois brug af et begreb om modernisme er problematisk - og i uoverenstemmelse med den overordnede karakter af hendes tilgang til Ibsens dramatik. Udgivelsesdato: 30.10.06......Anmelse af Toril Mois bog Ibsens modernisme. Bemærker bl.a. hvordan Mois brug af et begreb om modernisme er problematisk - og i uoverenstemmelse med den overordnede karakter af hendes tilgang til Ibsens dramatik. Udgivelsesdato: 30.10.06...

e quotidien à tout prix. Analyse du retour à l’ordinaire dans Le drap d’Yves Ravey et Un an de Jean Echenoz

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Isabelle Décarie

2007-06-01

Full Text Available Pourquoi le quotidien reprend-il le dessus avec force dans les occasions les moins courantes, comme celle d’une maladie mortelle ou d’une fugue à la suite d’un crime ? Comment le quotidien est-il raconté dans de telles circonstances ? Ces questions préliminaires guident ici l’analyse de deux romans, Le drap d’Yves Ravey (2002 et Un an de Jean Echenoz (1997, dans lesquels des événements, qui rompent pourtant avec le quotidien des personnages, sont chaque fois dépassés pour faire place au retour du temps ordinaire. Il s’agit ici de voir comment les romanciers parviennent à maintenir un récit de tous les jours tout en racontant une situation peu banale, puis de tenter de répondre à cette autre interrogation : quelle force nous pousse à vouloir à tout prix raconter le quotidien malgré des circonstances dramatiques ? Why does everyday life take over even in the least mundane of occasions, as is the case with a terminal illness or a disappearance after a crime ? How is everyday life narrated in such circumstances ? These preliminary questions guide the analysis of two novels, Le drap by Yves Ravey (2002 and Un an by Jean Echenoz (1997, two books in which events, although far from ordinary, are each time transcended to herald the return of everyday life. This article explores the ways in which Echenoz and Ravey manage to tell an extraordinary story while narrating ordinary events and tries to answer the question : what force compels us to tell the story of the ordinary at any price, even when confronted with dramatic circumstances ?

Les épouses de mon père. À propos de la polygamie en pays beti

Directory of Open Access Journals (Sweden)

Michael Houseman

2009-03-01

Full Text Available Les épouses de mon père. À propos de la polygamie en pays beti. Chez les Beti du Cameroun, un homme de conséquence se reconnaît, entre autres choses, par son aptitude à entretenir un foyer polygame. En retraçant la carrière matrimoniale du père de famille de la maison où je résidais, les rapports conflictuels entre ses épouses ainsi que mes propres relations avec elles — dont notamment une intervention désastreuse que j’ai essayé de réparer treize ans plus tard —, je tente dans cet article de faire ressortir à la fois la précarité de l’entente polygyne et la place essentielle qu’occupe cette instabilité dans le cycle de développement des groupes domestiques.The wives of my father: polygamy in Beti country. Among the Beti of Cameroon, one way of recognising a man of importance is by his ability to maintain a polygamous household. By retracing the matrimonial career of the father of the family I was staying with, the antagonistic relations between the wives, and my own relations with them - including one disastrous intervention that I tried to repair thirteen years later -, this article aims to bring to light both the precarious nature of the polygynous concord and the important role this instability plays in the development cycle of domestic groups.

Effective 226Ra-content of some Hungarian building materials

International Nuclear Information System (INIS)

Toth, A.; Feher, I.

1976-01-01

The aim of the work was to analyse the effective 226 Ra content of building- and back filling materials used in Hungary. The quantity of radon was determined by ionization chambers connected to vibrating-reed electrometers, as well as by a scintillation radon counter. The radon measuring instruments were calibrated by known 222 Rn quantities given off from standard RaCl 2 solutions. The overall uncertainty of the data obtained is estimated as being 25%. The minimum measurable effective 226 Ra concentration due to a 10 4 g building material source is calculated as 16 fCi/g for the ionization chambers and 8 fCi/g for the scintillation counter. 68 building material samples and 11 backfill (concrete made by fly-ashes) samples have been studied and it has been found, that the effective 226 Ra contents of the tested building materials are 2 to 9 times greater than those found in the Soviet Union though none exceeds the recommended 600 fCi/g level. Among the back filling materials made with fly-ash the maximum 226 Ra content was 3300 fCi/g. The effective 226 Ra content measurements are well suited for a priori radon escape qualification of building materials. (K.A.)

"Laisse-moi rire! Fais-moi parler!" ("Let Me Laugh! Make Me Speak!").

Science.gov (United States)

Borgomano, Laure

1983-01-01

A discussion of the use of cartoons and humorous vignettes in French instruction is presented. It is suggested that there exists a wealth of such material but little guidance in using it. Problems of cultural context, understanding the use of pictures, and potential for classroom discussion are considered. (MSE)

Analisi della qualità in biblioteca: la soluzione SiMonLib™@CASPUR

Directory of Open Access Journals (Sweden)

Ugo Contino

2011-12-01

Full Text Available ItLa raccolta periodica di dati e l’analisi delle performance, in un’ottica di valutazione della Qualità del Servizio, sono sicuramente elementi rilevanti per coloro che s’interessino della gestione di una biblioteca o di un sistema bibliotecario. Modi sempre più efficienti e ottimizzati per gestire specifiche campagne di raccolta dati non possono prescindere dall’uso di strumenti in ambito ICT, soprattutto per far fronte ai non banali problemi logistico organizzativi che simili attività di raccolta dati possono comportare. In quest’ambito merita sicuramente menzione SimonLib™, un software prodotto dalla XSystems di Cagliari e pensato per gestire i processi di raccolta dati e misura della qualità in biblioteca, sia essa singola o appartenente ad un sistema. Conscio delle potenzialità offerte da questa piattaforma, il CASPUR ha sottoscritto recentemente un accordo con XSystems per offrire SimonLib alla comunità delle biblioteche italiane, sia pubbliche che private. Il servizio offerto, SiMonLib@CASPUR, installato all’interno di un’infrastruttura di server virtuali (Service Cloud presso il CED del CASPUR, prevede l’accesso in piattaforma in modalità SaaS (Software as a Service, che garantisce le piene funzionalità del servizio ad un costo notevolmente contenuto.EnLibrarians and managers of a library system have to face with relevant problems when service quality measurement in libraries is concerned. The usage of ICT based solutions for measurement campaign, data assessment and analysis, seems to be an efficient way to cope with those issues. In the past few years a software company from Cagliari (XSystems has introduced a complete, web based software solution for quality measurement in a library or a library system, called SimonLib™, that can easily address the typical technical and logistic obstacles of complex service quality measurement process. In order to offer a reliable service based on SimonLib software for

Case report

African Journals Online (AJOL)

abp

27 janv. 2014 ... revenue normale. La patiente est mise sous traitement antibacillaire, pendant 9 mois, selon le protocole: rifampicine,isoniazide, pirazinamide et éthambutol pendant 2 mois, puis 7 mois de rifampicine et d'isoniazide. L'évolution après .... PubMed | Google Scholar. 2. Moutaouakil A, Kari B, Zadnass A. La ...

37. Fais dodo, Colas

OpenAIRE

Delarue, Georges; Massignon, Geneviève

2014-01-01

A) M. Jérôme Bujold, Saint-Jules-de-Maria (Bonaventure), P. Q. 1946 : Recueillie en décembre 1946 Notée par une personne de l’entourage du chanteur. MÉLODIE 37-A Fais dodo, mon titi, mon Colas,Fais dodo, mon titi, mon Colas.Quand papa reviendraApport’ra des p’tits chats.Fais dodo, mon titi, mon p’tit frère,Fais dodo, mon titi, mon Colas. B) Mme Edouard Savoie, Haut-Lamèque (Gloucester), N.-B. 46 : Recueillie en août 1946. PAS DE MÉLODIE NOTÉE Fais dodo, Colas mon p’tit frère,Fais dodo, t’aura...

[Detection of recombinant-DNA in foods from stacked genetically modified plants].

Science.gov (United States)

Sorokina, E Iu; Chernyshova, O N

2012-01-01

A quantitative real-time multiplex polymerase chain reaction method was applied to the detection and quantification of MON863 and MON810 in stacked genetically modified maize MON 810xMON 863. The limit of detection was approximately 0,1%. The accuracy of the quantification, measured as bias from the accepted value and the relative repeatability standard deviation, which measures the intra-laboratory variability, were within 25% at each GM-level. A method verification has demonstrated that the MON 863 and the MON810 methods can be equally applied in quantification of the respective events in stacked MON810xMON 863.

Une rencontre PAS comme les autres | CRDI - Centre de recherches ...

International Development Research Centre (IDRC) Digital Library (Canada)

15 oct. 2010 ... Dans ce récit à la première personne, Angelica Ospina, administratrice de programmes principale au CRDI , raconte sa rencontre avec Orlando, un jeune graphiste péruvien remarquable qui lutte en première ligne contre le VIH/sida dans son pays. Angelica a fait la connaissance d'Orlando et d'autres ...

Dis-moi quels champignons...

OpenAIRE

Lévi-Strauss, Claude

2010-01-01

Nous croyons tous, ou presque, être amateurs de champignons. Paris a donné son nom à la seule espèce européenne cultivée, le champignon figure à nos menus, c’est une « garniture » prescrite de la cuisine d’apparat. Pourtant, interrogez autour de vous, demandez à vos amis le nombre d’espèces connues et consommées par eux : ils vous parleront du champignon de Paris, du cèpe, de la girolle, de la morille, de la truffe. Bien rares ceux qui iront au-delà. Cette attitude timorée envers les champign...

Cordelia c'est moi

DEFF Research Database (Denmark)

Dehs, Jørgen

1987-01-01

Kritik af jean Baudrillard's tolkning af Søren Kierkegaad: Forførens dagbog, som den kommer til udtryk i bogen "Forførelse".......Kritik af jean Baudrillard's tolkning af Søren Kierkegaad: Forførens dagbog, som den kommer til udtryk i bogen "Forførelse"....

Effects of feeding Bt MON810 maize to pigs for 110 days on peripheral immune response and digestive fate of the cry1Ab gene and truncated Bt toxin.

Directory of Open Access Journals (Sweden)

Maria C Walsh

Full Text Available BACKGROUND: The objective of this study was to evaluate potential long-term (110 days and age-specific effects of feeding genetically modified Bt maize on peripheral immune response in pigs and to determine the digestive fate of the cry1Ab gene and truncated Bt toxin. METHODOLOGY/PRINCIPAL FINDINGS: Forty day old pigs (n = 40 were fed one of the following treatments: 1 isogenic maize-based diet for 110 days (isogenic; 2 Bt maize-based diet (MON810 for 110 days (Bt; 3 Isogenic maize-based diet for 30 days followed by Bt maize-based diet for 80 days (isogenic/Bt; and 4 Bt maize-based diet (MON810 for 30 days followed by isogenic maize-based diet for 80 days (Bt/isogenic. Blood samples were collected during the study for haematological analysis, measurement of cytokine and Cry1Ab-specific antibody production, immune cell phenotyping and cry1Ab gene and truncated Bt toxin detection. Pigs were sacrificed on day 110 and digesta and organ samples were taken for detection of the cry1Ab gene and the truncated Bt toxin. On day 100, lymphocyte counts were higher (P<0.05 in pigs fed Bt/isogenic than pigs fed Bt or isogenic. Erythrocyte counts on day 100 were lower in pigs fed Bt or isogenic/Bt than pigs fed Bt/isogenic (P<0.05. Neither the truncated Bt toxin nor the cry1Ab gene were detected in the organs or blood of pigs fed Bt maize. The cry1Ab gene was detected in stomach digesta and at low frequency in the ileum but not in the distal gastrointestinal tract (GIT, while the Bt toxin fragments were detected at all sites in the GIT. CONCLUSIONS/SIGNIFICANCE: Perturbations in peripheral immune response were thought not to be age-specific and were not indicative of Th 2 type allergenic or Th 1 type inflammatory responses. There was no evidence of cry1Ab gene or Bt toxin translocation to organs or blood following long-term feeding.

Lipid entrapment property of polysaccharide gel (PG extracted from fruit-hulls of durian (Durio zibethinus Murr. Cv. Mon-Thong

Directory of Open Access Journals (Sweden)

Maneewan Suksomtip

2005-03-01

Full Text Available Lipid entrapment property of polysaccharide gel (PG extracted from fruit-hulls of durian (Durio zibethinus Murr. Cv. Mon-Thong was investigated in vitro by semi- permeable membrane dialysis technique using both cellulose membrane and gut sacs of disected jejunum of rat. Lipids (cholesterol, oleic acid and stearic acid were mixed with 0-2%W/V PG in the presence of bile salt as a surface active agent in dialysis membrane. Lipids inside and outside dialysis membrane were analyzed by HPLC method after 4-16 hours of dialysis in Ringer lactate buffer pH7. Increasing PG concentration resulted in increasing lipids trapped inside membrane and decreasing lipids released outside membrane. Two percent PG trapped about 80-90%cholesterol. The result of PG trapping cholesterol in egg york showed that egg york cholesterol released outside membrane was decreased with increasing PG concentration. A significant relationship was found between the decreasing of absorbed cholesterol into everted rat jejunum with respect to increasing concen- tration of PG. These results suggested that durian polysaccharide gel is able to entrap lipids and it seems to have potential use as medicinal dietary food for lipid controlling patient. Furthermore, in vitro study using cellulose semi- permeable membrane dialysis method may be applied for preliminary evaluation of polysaccharide effecting lipids absorption.

Mobile Sensor System AGaMon for Breath Control: Numerical Signal Analysis of Ternary Gas Mixtures and First Field Tests

Directory of Open Access Journals (Sweden)

Rolf Seifert

2018-01-01

Full Text Available An innovative mobile sensor system for breath control in the exhaled air is introduced. In this paper, the application of alcohol control in the exhaled air is considered. This sensor system operates semiconducting gas sensor elements with respect to the application in a thermo-cyclic operation mode. This operation mode leads to so-called conductance-over-time-profiles (CTPs, which are fingerprints of the gas mixture under consideration and can be used for substance identification and concentration determination. Especially for the alcohol control in the exhaled air, ethanol is the leading gas component to be investigated. But, there are also other interfering gas components in the exhaled air, like H2 and acetone, which may influence the measurement results. Therefore, a ternary ethanol-H2-acetone gas mixture was investigated. The establishing of the mathematical calibration model and the data analysis was performed with a newly developed innovative calibration and evaluation procedure called ProSens 3.0. The analysis of ternary ethanol-H2-acetone gas samples with ProSens 3.0 shows a very good substance identification performance and a very good concentration determination of the leading ethanol component. The relative analysis errors for the leading component ethanol were in all considered samples less than 9 %. First field test performed with the sensor system AGaMon shows very promising results.

Specific feature of magnetooptical images of stray fields of magnets of various geometrical shapes

Science.gov (United States)

Ivanov, V. E.; Koveshnikov, A. V.; Andreev, S. V.

2017-08-01

Specific features of magnetooptical images (MOIs) of stray fields near the faces of prismatic hard magnetic elements have been studied. Attention has primarily been focused on MOIs of fields near faces oriented perpendicular to the magnetic moment of hard magnetic elements. With regard to the polar sensitivity, MOIs have practically uniform brightness and geometrically they coincide with the figures of the bases of the elements. With regard to longitudinal sensitivity, MOIs consist of several sectors, the number of which is determined by the number of angles of the image. Each angle is divided by the bisectrix into two sectors of different brightnesses; therefore, the MOI of a triangular magnet consists of three sectors. A rectangle consists of four sectors separated by the bisectrices of the interior angles. In all types of figures, these lines converge at the center of the figure and form a singular point of the source or sink type.

Mutagenesis-mediated virus extinction: virus-dependent effect of viral load on sensitivity to lethal defection.

Directory of Open Access Journals (Sweden)

Héctor Moreno

Full Text Available BACKGROUND: Lethal mutagenesis is a transition towards virus extinction mediated by enhanced mutation rates during viral genome replication, and it is currently under investigation as a potential new antiviral strategy. Viral load and virus fitness are known to influence virus extinction. Here we examine the effect or the multiplicity of infection (MOI on progeny production of several RNA viruses under enhanced mutagenesis. RESULTS: The effect of the mutagenic base analogue 5-fluorouracil (FU on the replication of the arenavirus lymphocytic choriomeningitis virus (LCMV can result either in inhibition of progeny production and virus extinction in infections carried out at low multiplicity of infection (MOI, or in a moderate titer decrease without extinction at high MOI. The effect of the MOI is similar for LCMV and vesicular stomatitis virus (VSV, but minimal or absent for the picornaviruses foot-and-mouth disease virus (FMDV and encephalomyocarditis virus (EMCV. The increase in mutation frequency and Shannon entropy (mutant spectrum complexity as a result of virus passage in the presence of FU was more accentuated at low MOI for LCMV and VSV, and at high MOI for FMDV and EMCV. We present an extension of the lethal defection model that agrees with the experimental results. CONCLUSIONS: (i Low infecting load favoured the extinction of negative strand viruses, LCMV or VSV, with an increase of mutant spectrum complexity. (ii This behaviour is not observed in RNA positive strand viruses, FMDV or EMCV. (iii The accumulation of defector genomes may underlie the MOI-dependent behaviour. (iv LCMV coinfections are allowed but superinfection is strongly restricted in BHK-21 cells. (v The dissimilar effects of the MOI on the efficiency of mutagenic-based extinction of different RNA viruses can have implications for the design of antiviral protocols based on lethal mutagenesis, presently under development.

Comparing Two Modes of Instruction in English Passive Structures (Processing and Meaning-Based Output Instruction

Directory of Open Access Journals (Sweden)

Asma Dabiri

2018-04-01

Full Text Available This research compared the effects of two types of instruction: Processing Instruction (PI and Meaning-based Output Instruction (MOI on the interpretation and production of English passive structures.  Ninety EFL intermediate tertiary level female students (PI group= 30, MOI group= 30 and control group = 30 participated in this study. The instruments were a proficiency test, a test to assess English passive structures and two instructional materials (PI and MOI. The data were analyzed by running one-way analysis of variance (ANOVA and mixed between-within ANOVA. The study indicated the effectiveness of PI and MOI on English passive structures. PI had considerable enhancement on interpretation tasks all the time. It supported the use of PI rather than the use of traditional instructions in which mechanical components were emphasized. Also, the PI and MOI had long term effects on the interpretation and production of English passive sentences.  This study supported the use of PI and MOI rather than the use of traditional instruction (TI in EFL settings. The implication for particularly classroom teaching is that successful grammar instruction has to related to ultimate learning outcomes. Also, creating communicative tasks to offer opportunities for teaching grammar can lead to long-lasting learning effects.

Faible taux de succes du sevrage tabagique a court et moyen termes au decours d�un infarctus aigu du myocarde dans un service de cardiologie de Dakar au Senegal

Directory of Open Access Journals (Sweden)

Alassane Mbaye

2011-10-01

Full Text Available e le tabac pendant l�hospitalisation. Apres un suivi de 3 mois, 45% des patients ont repris le tabac, 65% a 6 mois et 85% a 12 mois. CONCLUSION: Le tabagisme est assez frequent chez les patients senegalais presentant un infarctus du myocarde. Le taux de sevrage tabagique a court et moyen termes est faible. Le sevrage tabagique devrait alors constituer un objectif privilegie dans la prevention des maladies cardio-vasculaires.

Algunas cuestiones epistemológicas a propósito de la teología monástica medieval en Jean Leclercq

Directory of Open Access Journals (Sweden)

Pedro Edmundo Gómez, osb

2006-12-01

Full Text Available Este artículo plantea cuatro cuestiones epistemológicas a propósito de la teología monástica medieval: existencia y significado, distinción de la escolástica, noción de ciencia y crítica neoescolástica, exponiendo reverentemente lo que Dom Jean Leclercq, osb. monje, historiador y teólogo, enseñó especialmente en L'amour des lettres et le désir de Dieu, que es a la vez el título y la conclusión de un hermoso libro publicado hace ya cincuenta años, mostrando la posible "complementariedad" y "coexistencia pacífica" entre modos diversos de hacer teologíaThis article outlines four epistemological questions apropos of medieval monastic theology: existence and meaning, the scholastic distinction, the notion of science and neo-scholastic criticism, expounding reverently what monk, historian and theologian Dom Jean Leclercq, o.s.b., taught, especially in L'amour des letters et le désir de Dieu, which is at the same time the title and the conclusion of a beautiful book published 50 years ago, showing the possible "complementarity" and "peaceful co-existence" between different modes of doing theology

La tentation de l'inaccessible. Structures narratives chez Simenon

NARCIS (Netherlands)

Veldman, Hendrik

1981-01-01

Libération de l'homme individuel - Le plus souvent, un roman de Simenon raconte la transgression d'une ligne morale ou sociale, la violation de normes imposées par d'autres. C'est le récit du changement existentiel d'un homme ou d'une femme; d'un processus de libération et de ses conséquences d'une

Obstacles to Implementing Initiatives of Social Responsibility in Small and Medium-Size Firms Įmonių socialinė atsakomybė ir jos iniciatyvų diegimo kliūtys smulkiojo ir vidutinio verslo įmonėse

Directory of Open Access Journals (Sweden)

Rima Česynienė

2011-02-01

research of CSR initiatives implementation in business prac-tices were presented in the possible model of tools which stimulates social responsibility initiatives in small and medium-size business firms. This integrated model includes pu-blic, government and business efforts and interests: 1 improvement of public policy, 2 revitalization of public organizations; 3 encourage and support research, 4 integration of CSR into education, 5 singleness of purpose (depending on companies’ specifics, 6 increase of managers’ consciousness, 7 implementation of a step-by-step approach.

Keywords: corporate social responsibility, small and medium-size enterprise, sustainable development.

Įmonių socialinės atsakomybės (ĮSA idėja, kuria grindžiamas 1999 m. pasaulinis susitarimas, dar tik skinasi kelią Lietuvos įmonėse, o klestinčios Vakarų šalių įmonės kasdien demonstruoja naujas socialiai atsakingo verslo iniciatyvas, savo veiklą grįsdamos aplinkosaugos, skaidrumo, personalo ugdymo ir kitais naujojo bendrabūvio kūrimo principais. ĮSA didina įmonių vertę įvairiais aspektais: padeda sumažinti išlaidas, pritraukti daugiau investicijų, veiksmingiau spręsti restruktūrizavimo klausimus, pritraukti ir išlaikyti geriausius darbuotojus. Nuoseklus ĮSA skatinimas gali padėti spręsti tokias problemas kaip masinė emigracija, aplinkos užterštumas, geresnio šalies įvaizdžio formavimas. Nors dažnai teigiama, kad ĮSA koncepcija yra stambiųjų įmonių varomoji jėga, socialinės atsakomybės praktika egzistuoja ir smulkiojo bei

Non-adherence to anti-retroviral therapy among HIV infected adults in Mon State of Myanmar

Directory of Open Access Journals (Sweden)

Win Lei Aye

2017-05-01

Full Text Available Abstract Background The provision of Anti-Retroviral Therapy (ART was started in Myanmar in 2005 in collaboration with the National AIDS Program and the private sector. Successful clinical management of HIV-infected patients is subject to optimal adherence. The aim of the study was to determine the prevalence of adherence to ART and identify factors associated with non-adherence to ART among HIV infected adults registered in a private sector setting in Mon State, Myanmar. Methods This cross-sectional study was conducted with adults living with HIV receiving ART at an HIV outpatient clinic between April and May 2016. A total of three hundred People Living with HIV(PLHIV were interviewed using a pretested and structured questionnaire. The 30 days Visual Analog Scale (VAS adherence instrument was used to assess the level of adherence. Multivariable logistic regression analysis was used to determine factors associated with non-adherence to ART. Results Among 300 patients (male 37.7% and female 62.3%, with a mean age of 41.3 years, standard deviation 8.7, 84% reported ≥95% adherence to ART in the past month. Among 16% of those reporting non-adherence, major reasons for skipping the medication were being busy (23%, being away from home (17.7% and being forgetful (12.3%. In multivariable logistic rgeression, low behavioural skills on ART adherence (OR = 0.31, 95% CI: 0.10-0.94, tobacco use (OR = 3.22, 95% CI:1.28-8.12, having disclosed their HIV status (OR = 0.07, 95% CI: 0.01-0.69, having a partner who was not on ART (OR = 4.25, 95% CI: 1.70-10.64 and among men, having erectile dysfunction (OR = 15.14, 95% CI: 1.41-162.66 were significant associated with ART non-adherence. Conclusion Non-adherence to ART was associated with individual moderating factors and behavioral skills. Priority measures such as addressing risk behaviour and behavioural change communication tailored to individual patients’ lifestyles requires comprehensive

Non-adherence to anti-retroviral therapy among HIV infected adults in Mon State of Myanmar.

Science.gov (United States)

Aye, Win Lei; Puckpinyo, Apa; Peltzer, Karl

2017-05-05

The provision of Anti-Retroviral Therapy (ART) was started in Myanmar in 2005 in collaboration with the National AIDS Program and the private sector. Successful clinical management of HIV-infected patients is subject to optimal adherence. The aim of the study was to determine the prevalence of adherence to ART and identify factors associated with non-adherence to ART among HIV infected adults registered in a private sector setting in Mon State, Myanmar. This cross-sectional study was conducted with adults living with HIV receiving ART at an HIV outpatient clinic between April and May 2016. A total of three hundred People Living with HIV(PLHIV) were interviewed using a pretested and structured questionnaire. The 30 days Visual Analog Scale (VAS) adherence instrument was used to assess the level of adherence. Multivariable logistic regression analysis was used to determine factors associated with non-adherence to ART. Among 300 patients (male 37.7% and female 62.3%, with a mean age of 41.3 years, standard deviation 8.7), 84% reported ≥95% adherence to ART in the past month. Among 16% of those reporting non-adherence, major reasons for skipping the medication were being busy (23%), being away from home (17.7%) and being forgetful (12.3%). In multivariable logistic rgeression, low behavioural skills on ART adherence (OR = 0.31, 95% CI: 0.10-0.94), tobacco use (OR = 3.22, 95% CI:1.28-8.12), having disclosed their HIV status (OR = 0.07, 95% CI: 0.01-0.69), having a partner who was not on ART (OR = 4.25, 95% CI: 1.70-10.64) and among men, having erectile dysfunction (OR = 15.14, 95% CI: 1.41-162.66) were significant associated with ART non-adherence. Non-adherence to ART was associated with individual moderating factors and behavioral skills. Priority measures such as addressing risk behaviour and behavioural change communication tailored to individual patients' lifestyles requires comprehensive interventions to improve adherence.

An Optimistic Analysis of the Means of Implementation for Sustainable Development Goals: Thinking about Goals as Means

Directory of Open Access Journals (Sweden)

Mark Elder

2016-09-01

Full Text Available A key but contentious aspect of Sustainable Development Goals (SDGs is the means of implementation (MOI. Many developing countries emphasize the importance of international assistance while developed countries focus more on domestic financing and the private sector. The text of the SDGs includes a broad range of MOI. However, a discussion has arisen about whether countries should prioritize some goals over others due partly to concerns that MOI may be insufficient. In contrast, this article argues for a more optimistic outlook concerning MOI and the feasibility of achieving the SDGs. First, most SDGs and targets are themselves means—or intermediate goals—contributing to the achievement of other goals. The structure of the SDGs blurs the fact that different goals have different functions, such as providing resources or enabling environments. Greater focus on the interlinkages and synergies among goals could enhance the effectiveness of implementation and reduce costs. Second, integrated planning and implementation, needed for leveraging synergies among goals, will require enhanced capacity, particularly for governance and coordination. We argue that the strengthening of such capacity is a central MOI that requires more attention since it is a precondition for the effective mobilization and deployment of other MOI. Third, although upfront investments may seem high in absolute terms, financial feasibility is realistic when considering existing global financial stocks and flows and the expected benefits.

Metabolism of early-lactation dairy cows as affected by dietary starch and monensin supplementation.

Science.gov (United States)

McCarthy, M M; Yasui, T; Ryan, C M; Pelton, S H; Mechor, G D; Overton, T R

2015-05-01

The objective of this study was to evaluate the effect of dietary starch content and monensin (MON) on metabolism of dairy cows during early lactation. Before parturition, primiparous (n=21) and multiparous (n=49) Holstein cows were fed a common controlled-energy close-up diet with a daily topdress of either 0 or 400mg/d monensin. From d 1 to 21 postpartum, cows were fed a high-starch (HS; 26.2% starch, 34.3% neutral detergent fiber, 22.7% acid detergent fiber, 15.5% crude protein) or low-starch (LS; 21.5% starch, 36.9% neutral detergent fiber, 25.2% acid detergent fiber, 15.4% crude protein) total mixed ration with a daily topdress of either 0mg/d monensin (CON) or 450mg/d monensin (MON), continuing with prepartum topdress assignment. From d 22 through 63 postpartum, all cows were fed HS and continued with the assigned topdress treatment until d 63. Cows fed HS had higher plasma glucose and insulin and lower nonesterified fatty acids (NEFA) than cows fed LS during d 1 to 21 postpartum. Cows fed LS had elevated early-lactation β-hydroxybutyrate (BHBA) compared with cows fed HS. Cows fed HS had greater insulin resistance and increased plasma haptoglobin in the early lactation period. There was no effect of MON on postpartum plasma NEFA. Cows fed MON had higher plasma glucose compared with CON cows, which was driven by a MON × parity interaction in which primiparous cows fed MON had greater plasma glucose concentrations than cows fed CON. Cows fed MON had lower plasma BHBA compared with CON, which was contributed to by a MON × parity interaction in which primiparous cows fed MON had lower BHBA concentrations than CON. Starch treatment had no effect on overall liver triglyceride content. Primiparous cows fed MON had increased liver triglyceride content compared with CON primiparous cows, and multiparous cows fed MON had decreased liver triglyceride content compared with CON cows. Multiparous cows fed LS with MON had higher liver glycogen content than multiparous

Test de respiración única para la capacidad de difusión de monóxido de carbono (DLCO) y su interpretación en enfermedades autoinmunes. Aplicación en la práctica clínica -Segunda Parte-

OpenAIRE

Mora Alfonso, Sergio Alexander; Bello Gualtero, Juan Manuel; Londoño, John; Valle-Oñate, Rafael Raúl; Quintana, Gerardo

2011-01-01

El test de respiración única ha probado por si mismo ser una parte esencial del tamizaje de rutina de la función pulmonar, y de igual valor que la espirometría. A pesar de 100 años de investigación, aún no existe certeza sobre la relativa importancia de las membranas alveolo-capilares vs los eritrocitos como los pasos que sean delimitantes en el transporte global del monóxido de carbono del gas hacia la sangre, pero esto es solo un problema cuantitativo. La naturaleza esencial del test de DLC...

Pubic contouring after massive weight loss in men and women: correction of hidden penis, mons ptosis, and labia majora enlargement.

Science.gov (United States)

Alter, Gary J

2012-10-01

Weight gain and subsequent weight loss usually result in unsightly large fat deposition in the pubic areas along with ptosis of the fat pad and skin. Men also complain of burying of the penis and the woman complains of labia majora enlargement, both causing secondary sexual dysfunction, hygiene issues, discomfort, and aesthetic concerns. Even with weight loss, most of these deformities persist. The hidden (buried) penis is characterized by a lack of firm attachments between the Buck fascia surrounding the tunica albuginea of the corpora and the dartos fascia and skin. Successful treatment requires the penile skin and dartos fascia to be stabilized to the penile corporal bodies to make the penis one integrated unit. The method of surgery is usually to excise and lift excess pubic skin, eliminate the pubic fat without creating a significant pubic concavity, and stabilize the penile skin to the corporal bodies with tacking sutures dorsally and ventrally. If inadequate penile skin is present, scrotal flaps or skin grafts are used to cover the penis. Treatment of the mons pubis requires similar pubic lifting, fat excision, and pubic tacking. Labia majora reduction requires skin and usually fat excision. Results are excellent with the use of these techniques. Pubic contouring after massive weight loss in men and women is very successful and safe if performed meticulously. Treatment improves self-esteem along with the associated physical and aesthetic deformities.

Les femmes prennent appui sur le souvenir de la guerre pour ...

International Development Research Centre (IDRC) Digital Library (Canada)

Selon Judith Erazo, la peur hante les survivantes, et la stigmatisation culturelle généralisée de la violence sexuelle les empêche de raconter ce qu'elles ont vécu. La violence faite aux femmes empoisonne également la vie civile. En effet, les meurtres de femmes ont augmenté de manière considérable après les accords de ...

Diffusion et réception des chroniques : Chronica Naiarensis, Liber regum, Chronica regum Castellae

OpenAIRE

Arizaleta , Amaia

2006-01-01

International audience; Il est question dans ces pages des chroniques composées dans l'espace castillan au tournant du XIIe et du XIIIe siècles, afin d'avancer des informations sur le cadre pragmatique de réception des histoires royales qui devaient circuler au palais, ainsi que sur le plaisir de raconter que devaient ressentir les écrivains du roi et les auditeurs de la cour.

Growth of Listeria monocytogenes on a RTE-meat matrix enhances cell invasiveness to mouse J774A.1 macrophages.

Science.gov (United States)

Lin, Chen-Si; Wang, Chinling; Tsai, Hsiang-Jung; Chou, Chung-Hsi

2010-11-15

It remains unclear whether the growth of Listeria monocytogenes on a ready-to-eat (RTE) meat matrix has an impact on the bacterium's pathogenic abilities. In this study, we investigated the impact of environments on virulence by growing L. monocytogenes (F2365 strain) on brain heart infusion agar (BHI), tryptic soy agar (TSA), and RTE turkey meat matrices. Bacteria cultured from these media were harvested and used to infect mouse macrophage cell line J774A.1 with different MOIs to examine their invasion ability. At MOI=10 and 50, the numbers of bacteria recovered from cells infected with turkey-meat-grown Listeria were significantly higher than those from the two nutrient-rich growth media. Additionally, MOI played a role in determining L. monocytogenes recovery rates, since significant differences were found amongst all three groups at low MOI, while no significant differences were found between BHI and TSA groups at high MOI. These results indicate that environmental changes affect the ability of L. monocytogenes to invade and survive intracellularly while grown on RTE-meat matrix. Copyright © 2010 Elsevier B.V. All rights reserved.

Les découvreurs

CERN Document Server

Boorstin, Daniel

1986-01-01

Sous une forme vivante, enlevée, très personnelle, Les Découvreurs raconte la plus grande épopée de l'homme : celle de sa quête pour découvrir le monde qui l'entoure. Daniel Boorstin s'écarte volontairement de la traditionnelle et fastidieuse énumération des batailles, des naissances d'empires et des grands règnes : avec lui, l'histoire de notre monde devient une féerie de découvertes et de commencements. En chaque découverte d'importance, que ce soit celle de l'Amérique par Christophe Colomb ou celle de la relativité par Einstein, il voit un épisode d'une biographie. Les héros de la saga qu'il nous raconte sont des hommes dotés d'une insatiable frénésie de connaissance et d'un courage exemplaire pour affronter l'inconnu. Daniel Boorstin nous fait découvrir sous un jour nouveau des noms familiers : Hérodote, Ptolémée, Marco Polo, Copernic, Newton, Marx, Freud, et ressuscite également quelques figures remarquables oubliées de l'histoire. Pour quelles raisons les Chinois n'ont-ils pas...

[Rapid expression and preparation of the recombinant fusion protein sTNFRII-gAD by adenovirus vector system].

Science.gov (United States)

Lu, Yue; Liu, Dan; Zhang, Xiaoren; Liu, Xuerong; Shen, Wei; Zheng, Gang; Liu, Yunfan; Dong, Xiaoyan; Wu, Xiaobing; Gao, Jimin

2011-08-01

We expressed and prepared the recombinant fusion protein sTNFRII-gAD consisted of soluble TNF receptor II and the globular domain of adiponectin by Adenovirus Vector System in mammalian BHK21c022 cells. First we used the adenovirus vector containing EGFP gene (rAd5-EGFP) to infect BHK21c022 cells at different MOI (from 0 to 1 000), and then evaluated their transduction efficiency and cytotoxicity. Similarly, we constructed the replication-deficient adenovirus type 5-sTNFRII-gAD (rAd5-sTNFRII-gAD). We collected the supernatants for Western blotting to determine the optimal MOI by comparing the expression levels of sTNFRII-gAD fusion protein, 48 h after the BHK21c022 cells were infected by rAd5-sTNFRII-gAD at different MOIs (from 0 to 1 000). Then, we chose rAd5-sTNFRII-gAD at MOI 100 to infect five bottles of BHK21c022 cells in 100 mL of serum-free chemically defined media 100 mL, harvested the supernatant every 48 h for 6 times, and condense and purify sTNFRII-gAD fusion protein by ammonium sulfate salt-out and size-exclusion chromatography, respectively. Finally, we analyzed anti-TNFalpha activity of sTNFRII-gAD fusion protein on L929 cells in vitro. The results showed that the number of BHK21c022 cells expressing EGFP protein was increased significantly with the increase of MOI. However, some cells died at MOI of 1 000 while there was no significant cytotoxicity at MOI from 0 to 100. Western blotting analysis showed that the more adenoviruses, the higher expression of sTNFRII-gAD fusion protein in the supernatant with the highest expression at MOI 1 000. We successfully obtained about 11 mg bioactive and purified sTNFRII-gAD fusion protein at last. The in vitro assay demonstrated that the sTNFRII-gAD fusion protein was potent to antagonize TNFalpha's cytotoxicity to L929 cells. Put together, we established a recombinant adenovirus vector/BHK21 cell expression system, characteristic of the efficient serum-free culture and easy scaling-up.

Distribution spatiale intra-urbaine des particules fines : monitoring ...

African Journals Online (AJOL)

SARAH

30 sept. 2014 ... En outre, l'accumulation des particules fines est faible pendant un mois pluvieux par rapport à un mois sec ..... benjamina, et la structure (tige, branches) des arborées ... par Zhang et al., (2006) sur des feuilles de Pinus pumila.

Plasmodium falciparum multiplicity correlates with anaemia in symptomatic malaria

NARCIS (Netherlands)

Mockenhaupt, Frank P.; Ehrhardt, Stephan; Eggelte, Teunis A.; Markert, Miriam; Anemana, Sylvester; Otchwemah, Rowland; Bienzle, Ulrich

2003-01-01

In 366 Ghanaian children with symptomatic Plasmodium falciparum malaria, low haemoglobin levels and severe anaemia were associated with a high multiplicity of infection (MOI) and with distinct merozoite surface protein alleles. High MOI not only reflects premunition but may also contribute to

Stability, occurrence and step morphology of polymorphs and polytypes of stearic acid. I. Stability and occurrence

Science.gov (United States)

Sato, Kiyotaka; Kobayashi, Masamichi; Morishita, Hirofumi

1988-02-01

The thermodynamical stability and occurrence of three different structural modifications: monoclinic and pseudo-orthorhombic polytypes of the B polymorph, called B(mon) and B(orth II) respectively, and monoclinic C polymorph, C(mon), of stearic acid have been examined. The solubility measurements, overgrowth and isothermal crystallization proved that B(orth II) and C(mon) are most stable below and above 32°C, respectively, whereas B(mon) is always metastable, turning to be more stable than C(mon) below between 23 and 24°C. It was confirmed by micro-probe Raman spectroscopy that the polytypic structure of the newly-overgrown crystal on the (001) faces of the seed crystal of B(mon) changed from the original monoclinic to pseudo-orthorhombic, B(orth II), at very small supersaturations above 23°C. This conversion was caused by the solubility difference. The occurrence experiment indicated a slight tendency that B(mon) crystallized more than B(orth II) at lower temperatures.

Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of Ghana

DEFF Research Database (Denmark)

Amoah, L. E.; Nuvor, S. V.; Obboh, E. K.

2017-01-01

Background: Plasmodium falciparum genetic diversity and multiplicity of infection (MOI) are parasite features that have been suggested to influence the acquisition of protective immunity against malaria. This study sought to assess the relationship between MOI and parasite density (PD) in malaria...... and adults diagnosed with uncomplicated P. falciparum malaria. Microscopy was used to estimate P. falciparum parasite density and polymerase chain reaction (PCR) amplification of the polymorphic regions of msp1 (PF3D7-0930300) and msp2 (PF3D7-0206800) was used for parasite genotyping and MOI determination....... The geometric mean (GM) for MOI determined by both msp1 and msp2 genotyping was 1.3 for the entire population and was generally higher in children than in adults. Seropositivity was estimated at 67 and 63% for GLURP(R0) and MSP3 antibodies, respectively, and antibody titers were negatively correlated...

Avaliação do grau de exposição de amostras populacionais de São Paulo ao monóxido de carbono Evaluation of the degree of exposure of sample population groups in S. Paulo (Brazil to carbon monoxide

Directory of Open Access Journals (Sweden)

Nilda A. Gallego Gandara de Fernícola

1979-06-01

Full Text Available Com a finalidade de avaliar o grau de exposição ao monóxido de carbono da população da cidade de São Paulo (Brasil, foram coletadas 327 amostras de sangue de adultos, procedendo-se à determinação do conteúdo de carboxiemoglobina pela técnica espectrofotométrica. Trinta das amostras obtidas de residentes de uma cidade (Embú-Guaçu considerada, por suas características, como local de baixas concentrações de monóxido de carbono, foram tomadas como grupo-controle. Os valores de carboxiemoglobina encontrados foram os seguintes: policiais de trânsito: fumantes 6,3 ± 2,07, não fumantes 2,1 ± 0,68; motoristas de ônibus: fumantes 4,6 ± 1,94, não fumantes 1,6 ± 0,46; grupo-controle: fumantes 3,8 ± 1,74, não fumantes 0,8 ± 0,21.In order to evaluate the degree of exposure of the S. Paulo city (Brazil population to carbon monoxide, 327 blood samples from adults were collected and the carboxihemoglobin content determined by the spectrophotometric method. Thirty of these samples (control group were taken from residents of a city (Embú-Guaçu considered by its characteristics to be an area of low environmental carbon monoxide concentration. The following results were obtained: traffic policemen: smokers 6.3 ± 2.07, non-smokers 2.1 ± 0.68; bus drivers: smokers 4.6 ± 1.94, non-smokers 1.6 ± 0.46; control: smokers 3.8 ± 1.74, non-smokers 0.8 ± 0.21.

Field-evolved resistance to Bt maize in sugarcane borer (Diatraea saccharalis) in Argentina.

Science.gov (United States)

Grimi, Damián A; Parody, Betiana; Ramos, María Laura; Machado, Marcos; Ocampo, Federico; Willse, Alan; Martinelli, Samuel; Head, Graham

2018-04-01

Maize technologies expressing Bacillus thuringiensis (Bt) insecticidal proteins are widely used in Argentina to control sugarcane borer (Diatraea saccharalis Fabricius). Unexpected D. saccharalis damage was observed to Bt maize events TC1507 (expressing Cry1F) and MON 89034 × MON 88017 (expressing Cry1A.105 and Cry2Ab2) in an isolated area of San Luis Province. Diatraea saccharalis larvae were sampled from MON 89034 × MON 88017 fields in the area to generate a resistant strain (RR), which was subsequently characterized in plant and diet bioassays. Survivorship of the RR strain was high on TC1507 leaf tissue, intermediate on MON 89034 × MON 88017, and low on MON 810 (expressing Cry1Ab). The RR strain had high resistance to Cry1A.105 (186.74-fold) and no resistance to Cry2Ab2 in diet bioassays. These results indicate resistance to Cry1F and Cry1A.105 (and likely cross-resistance between them) but not to Cry1Ab or Cry2Ab2. Resistance to MON 89034 × MON 88017 was functionally recessive. Reviews of grower records suggest that resistance initially evolved to Cry1F, conferring cross-resistance to Cry1A.105, with low refuge compliance as the primary cause. A mitigation plan was implemented in San Luis that included technology rotation, field monitoring, and grower education on best management practices (BMPs) including refuges. In the affected area, the resistance to Cry1F and Cry1A.105 is being managed effectively through use of MON 89034 × MON 88017 and MON 810 in combination with BMPs, and no spread of resistance to other regions has been observed. © 2017 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. © 2017 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Developing INDCs: a guidance note

DEFF Research Database (Denmark)

Bakkegaard, Riyong Kim; Bee, Skylar; Naswa, Prakriti

needs and low capability, would need means of implementation (MoI) for adaptation and to take ambitious mitigation actions. Developing countries would include MoI needs in the context of mitigation and adaptation. The note explains briefly how countries can identify their unconditional contributions....

Value creation for consumers through marketing communications

OpenAIRE

Tatulytė, Vesta

2014-01-01

Norėdama užsitikrinti vietą rinkoje įmonė turi įgyti konkurencinį pranašumą kitų įmonių atžvilgiu. Įmonės konkurencini pranašumą lemia jos išskirtininkai gebėjimai, kurie siejami su įmonės personalo išskirtinėmis kompetencijomis ir išskirtiniais ištekliais. Šie ištekliai yra vertingi kai jų neturi kitos įmonės. Išteklių išskirtinumas turi būti ilgalaikis, nes per trumpą laiką įmonė gali nespėti juo pasinaudoti. Norėdama išlaikyti išteklių išskirtinumą, įmonė turi nuolat investuoti į išteklių ...

Rabatel, Alain, Argumenter en racontant, Bruxelles, De Boeck, 2004, 133 p.

Directory of Open Access Journals (Sweden)

2005-07-01

Full Text Available Alain Rabatel est professeur de Sciences du Langage à l’IUFM de Lyon. Ses nombreux travaux portent sur l’approche énonciative des textes littéraires et des interactions orales. Cet ouvrage, publié par l’éditeur belge De Boeck, dans la collection « Savoirs pratiques », est destiné aux formateurs ainsi qu’aux étudiants en lettres. Cependant, il s’adresse aussi à ceux qui s’intéressent à l’analyse et à la théorie du récit. Fondamentalement, ce livre repose sur les relations qu’entretient la nar...

Fate of Transgenic DNA from Orally Administered Bt MON810 Maize and Effects on Immune Response and Growth in Pigs

Science.gov (United States)

Walsh, Maria C.; Buzoianu, Stefan G.; Gardiner, Gillian E.; Rea, Mary C.; Gelencsér, Eva; Jánosi, Anna; Epstein, Michelle M.; Ross, R. Paul; Lawlor, Peadar G.

2011-01-01

We assessed the effect of short-term feeding of genetically modified (GM: Bt MON810) maize on immune responses and growth in weanling pigs and determined the fate of the transgenic DNA and protein in-vivo. Pigs were fed a diet containing 38.9% GM or non-GM isogenic parent line maize for 31 days. We observed that IL-12 and IFNγ production from mitogenic stimulated peripheral blood mononuclear cells decreased (PGM maize exposure. While Cry1Ab-specific IgG and IgA were not detected in the plasma of GM maize-fed pigs, the detection of the cry1Ab gene and protein was limited to the gastrointestinal digesta and was not found in the kidneys, liver, spleen, muscle, heart or blood. Feeding GM maize to weanling pigs had no effect on growth performance or body weight. IL-6 and IL-4 production from isolated splenocytes were increased (PGM maize while the proportion of CD4+ T cells in the spleen decreased. In the ileum, the proportion of B cells and macrophages decreased while the proportion of CD4+ T cells increased in GM maize-fed pigs. IL-8 and IL-4 production from isolated intraepithelial and lamina propria lymphocytes were also increased (PGM maize. In conclusion, there was no evidence of cry1Ab gene or protein translocation to the organs and blood of weaning pigs. The growth of pigs was not affected by feeding GM maize. Alterations in immune responses were detected; however, their biologic relevance is questionable. PMID:22132091

Successful labeling of 99mTc-MDP using 99mTc separated from 99Mo produced by 100Mo(n,2n)99Mo

International Nuclear Information System (INIS)

Nagai, Yasuki; Hatsukawa, Yuichi; Kin, Tadahiro; Hashimoto, Kazuyuki; Motoishi, Shoji; Konno, Chikara; Ochiai, Kentaro; Takakura, Kosuke; Sato, Yuichi; Sato, Norihito; Ohta, Akio; Yamabayashi, Hisamichi; Tanase, Masakazu; Fujisaki, Saburo; Kawauchi, Yukimasa; Teranaka, Tomoyuki; Takeuchi, Nobuhiro; Igarashi, Takashi

2011-01-01

We have for the first time succeeded in separating 99m Tc from a MoO 3 sample irradiated with accelerator neutrons free from any radioactive impurities and in formulating 99m Tc-methylene diphosphonate ( 99 mTc-MDP). 99 Mo, the mother nuclide of 99m Tc, was produced by the 100 Mo(n,2n) 99 Mo reaction using about 14 MeV neutrons provided by the 3 H(d,n) 4 He reaction at the Fusion Neutronics Source of Japan Atomic Energy Agency. The 99m Tc was separated from 99 Mo by sublimation and its radionuclide purity was confirmed to be higher than 99.99% by γ-spectroscopy. The labeling efficiency of 99m Tc-MDP was shown to be higher than 99% by thin-layer chromatography. These values exceed the United States Pharmacopeia requirements for a fission product, 99 Mo. Consequently, a 99m Tc radiopharmaceutical preparation formed by using the mentioned 99 Mo can be a promising substitute for the fission product 99 Mo, which is currently produced using a highly enriched uranium target in aging research reactors. A longstanding problem to ensure a reliable and constant supply of 99 Mo in Japan can be partially mitigated. (author)

nutritional status of children admitted for diarrhoeal diseases in a ...

African Journals Online (AJOL)

2013-07-07

Jul 7, 2013 ... Objectives: To determine the prevalence of malnutrition among children admitted with acute diarrhoea disease at Moi Teaching and Referral Hospital and to establish the effect of malnutrition on duration of hospital stay. Design: Prospective observational study. Setting: Paediatric wards of Moi Teaching and ...

The Biology of Autoimmune Response in the Scurfy Mice that Lack the CD4+Foxp3+ Regulatory T-Cells.

Science.gov (United States)

Ju, Shyr-Te; Sharma, Rahul; Gaskin, Felicia; Kung, John T; Fu, Shu Man

2012-04-04

Due to a mutation in the Foxp3 transcription factor, Scurfy mice lack regulatory T-cells that maintain self-tolerance of the immune system. They develop multi-organ inflammation (MOI) and die around four weeks old. The affected organs are skin, tail, lungs and liver. In humans, endocrine and gastrointestinal inflammation are also observed, hence the disease is termed IPEX (Immunodysregulation, Polyendocrinopathy, Enteropathy, X-linked) syndrome. The three week period of fatal MOI offers a useful autoimmune model in which the controls by genetics, T-cell subsets, cytokines, and effector mechanisms could be efficiently investigated. In this report, we will review published work, summarize our recent studies of Scurfy double mutants lacking specific autoimmune-related genes, discuss the cellular and cytokine controls by these genes on MOI, the organ-specificities of the MOI controlled by environments, and the effector mechanisms regulated by specific Th cytokines, including several newly identified control mechanisms for organ-specific autoimmune response.

Etat nutritionnel des enfants âgés de 6 à 59 mois infectés par le VIH mais non traités aux ARV à Lubumbashi

Science.gov (United States)

Mwadianvita, Costa Kazadi; Kanyenze, Faustin Ngoy; Wembonyama, Cecile Watu; Mutomb, Florence Mujing A; Mupoya, Kalombo; Nkoy, Albert Mwembo–Tambwe A; Mwenze, Prosper Kalenga

2014-01-01

Introduction L'infection par le VIH provoque et/ou aggrave les déficits nutritionnels de l'enfant. Ce travail avait pour objectif d'analyser l’état nutritionnel des enfants infectés par le VIH à Lubumbashi. Méthodes Une étude transversale portant sur 83 enfants âgés de 6 à 60 mois s'est déroulée de mai 2010 à mai 2011 dans trois(3) centres de prise en charge des Personnes Vivant avec le VIH(PVV), notamment le Centre d'Excellence(CE) de l'hôpital Sendwe, le Centre Amo-Congo de la Kenya et le Centre de Référence de la Kenya. Les statistiques descriptives usuelles ont été utilisées. Résultats La prévalence de la malnutrition globale était de 60,2% (n = 50) dont 8,4% de malnutrition sévère. Le poids moyen était de 11,6±4,1 kg avec un minimum de 5 kg et un maximum de 22 kg. Le taux d'hémoglobine moyen était d'environ 9,8± 2,0 g/dl avec une prévalence globale de l'anémie (hémoglobine VIH. La survenue de l'anémie n’était pas associée au déficit nutritionnel (p = 0,6). Conclusion Ces résultats révèlent que l'infection à VIH modifie l’état nutritionnel des enfants à Lubumbashi avec 60,2% de malnutrition globale et 8,4% de retard de croissance. Les enfants au stade avancé de l'infection à VIH en sont plus affectés. PMID:25574336

75 FR 24892 - Certain Coated Paper Suitable for High-Quality Print Graphics Using Sheet-Fed Presses From the...

Science.gov (United States)

2010-05-06

... inputs during the POI. MOI Respondents claim that the government did not regulate the quantity or pricing.... the import penetration ratio. The Department notes that MOI Respondents did not provide this metric... consider: (1) Whether the input is subject to any state guidance pricing, decrees, circulars, or other...

Language Policy-Making in Multilingual Education: Mass Media and the Framing of Medium of Instruction

Science.gov (United States)

Tollefson, James W.

2015-01-01

In some settings, medium of instruction (MOI) policies in multilingual education break out into public debates in mass media involving politicians, business leaders, government officials, parents, and school children. These public discussions of MOI often index struggles over the distribution of political power and economic resources, and issues…

The power to detect linkage in complex disease by means of simple LOD-score analyses.

Science.gov (United States)

Greenberg, D A; Abreu, P; Hodge, S E

1998-09-01

Maximum-likelihood analysis (via LOD score) provides the most powerful method for finding linkage when the mode of inheritance (MOI) is known. However, because one must assume an MOI, the application of LOD-score analysis to complex disease has been questioned. Although it is known that one can legitimately maximize the maximum LOD score with respect to genetic parameters, this approach raises three concerns: (1) multiple testing, (2) effect on power to detect linkage, and (3) adequacy of the approximate MOI for the true MOI. We evaluated the power of LOD scores to detect linkage when the true MOI was complex but a LOD score analysis assumed simple models. We simulated data from 14 different genetic models, including dominant and recessive at high (80%) and low (20%) penetrances, intermediate models, and several additive two-locus models. We calculated LOD scores by assuming two simple models, dominant and recessive, each with 50% penetrance, then took the higher of the two LOD scores as the raw test statistic and corrected for multiple tests. We call this test statistic "MMLS-C." We found that the ELODs for MMLS-C are >=80% of the ELOD under the true model when the ELOD for the true model is >=3. Similarly, the power to reach a given LOD score was usually >=80% that of the true model, when the power under the true model was >=60%. These results underscore that a critical factor in LOD-score analysis is the MOI at the linked locus, not that of the disease or trait per se. Thus, a limited set of simple genetic models in LOD-score analysis can work well in testing for linkage.

Biochemical and molecular characterization of Leishmania parasites isolated from an endemic focus in eastern Sudan

NARCIS (Netherlands)

Oskam, L.; Pratlong, F.; Zijlstra, E. E.; Kroon, C. C.; Dedet, I. P.; Kager, P. A.; Schönian, G.; Ghalib, H. W.; El-Hassan, A. M.; Meredith, S. E.

1998-01-01

Twelve Leishmania isolates from visceral leishmaniasis patients in eastern Sudan were characterized using isoenzyme analysis, Southern blotting and polymerase chain reaction (PCR) 'fingerprinting'. Isoenzyme analysis revealed the presence of 3 zymodemes: MON-18, MON-30 and MON-82, corresponding to

Influence of Percieved body Image on Nutrient Intake and Nutritional ...

African Journals Online (AJOL)

The main objective of this study was to investigate the perceived body image of Moi University undergraduate female students and its influence on their nutrient intake and nutritional health. Methods: Cross sectional Survey was done on 260 female students of Moi University aged 20-25. Stratified followed by systematic ...

The PB2, PA, HA, NP, and NS genes of a highly pathogenic avian influenza virus A/whooper swan/Mongolia/3/2005 (H5N1 are responsible for pathogenicity in ducks

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Kajihara Masahiro

2013-02-01

Full Text Available Abstract Background Wild ducks are the natural hosts of influenza A viruses. Duck influenza, therefore, has been believed inapparent infection with influenza A viruses, including highly pathogenic avian influenza viruses (HPAIVs in chickens. In fact, ducks experimentally infected with an HPAIV strain, A/Hong Kong/483/1997 (H5N1 (HK483, did not show any clinical signs. Another HPAIV strain, A/whooper swan/Mongolia/3/2005 (H5N1 (MON3 isolated from a dead swan, however, caused neurological dysfunction and death in ducks. Method To understand the mechanism whereby MON3 shows high pathogenicity in ducks, HK483, MON3, and twenty-four reassortants generated between these two H5N1 viruses were compared for their pathogenicity in domestic ducks. Results None of the ducks infected with MON3-based single-gene reassortants bearing the PB2, NP, or NS gene segment of HK483 died, and HK483-based single-gene reassortants bearing PB2, NP, or NS genes of MON3 were not pathogenic in ducks, suggesting that multiple gene segments contribute to the pathogenicity of MON3 in ducks. All the ducks infected with the reassortant bearing PB2, PA, HA, NP, and NS gene segments of MON3 died within five days post-inoculation, as did those infected with MON3. Each of the viruses was assessed for replication in ducks three days post-inoculation. MON3 and multi-gene reassortants pathogenic in ducks were recovered from all of the tissues examined and replicated with high titers in the brains and lungs. Conclusion The present results indicate that multigenic factors are responsible for efficient replication of MON3 in ducks. In particular, virus growth in the brain might correlate with neurological dysfunction and the disease severity.

Preliminary Evaluation of Moniliformin as a Potential Threat for Teleosts

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Rui Goncalves

2018-01-01

Full Text Available Aquaculture feed manufacturers and producers increasingly recognize the importance of mycotoxins, which contaminate plant-based meals used in compound aquafeeds, and their potential to negatively impact production. Though data on the worldwide occurrence of legislated mycotoxins e.g., trichothecenes and zearalenone (ZEN are well documented, relatively little information is available regarding other mycotoxins also produced by Fusarium, notably moniliformin (MON. Given that MON is known to affect the survival, growth, skeletal formation and bone mineralization in terrestrial species, its widespread occurrence on maize and maize by-products typically used in aquaculture makes it relevant to study these parameters in teleost fish. In the present work we have tested the effect of MON exposure on survival, bone development and mineralization using zebrafish (Danio rerio as a model species and fish derived osteo-chondroprogenitor cell line for in vitro studies. Moniliformin exposure did not decrease bone mineralization in zebrafish larvae or extracellular matrix mineralization in the mineralogenic cell line VSa13. Here, the minimal in vitro cytotoxicity concentration was found to be 1000 µg L−1 MON. Incidence of deformities was also not altered by MON at the concentration tested (450 µg L−1 although larval growth was affected, as shown by a decrease in the standard length of exposed specimens at 20 days post fertilization. Survival decreased significantly in larvae exposed to MON concentrations higher than 900 μg L−1. Influence of MON on survival and growth might be relevant for aquaculture industry. As MON is a water-soluble mycotoxin, its leaching from feed is highly probable, so MON assimilation into the surrounding aqueous environment should also be considered. Tested levels in fish larvae are within the reported occurrence levels of MON in commercial feed and plant meals.

Le procédé de blanchiment dans les ateliers monétaires français au XV-XVIème siècle: approche archéométrique et expérimentale

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Téreygeol, Florian

2011-12-01

Full Text Available In the late nineties, excavations in La Rochelle (France have discovered the remains of a royal mint of the sixteenth century. This discovery enabled the collection of artefacts directly related to the manufacture of coins. The exceptional corpus gathered is the subject of a study of the chaîne opératoire of coining in the medieval time. Special attention is paid to an operation which takes place before the strike: the blanching of blanks. Well documented in ancient times, the samples from La Rochelle offer the opportunity to study this process during the medieval period and in a royal mint. In addition, thanks to reconstitution experiments, it is possible to define a reaction mechanism that helps to understand our historical observations.[fr] À la fin des années quatre-vingtdix, des fouilles menées à La Rochelle (France ont permis de mettre au jour les vestiges d’un atelier monétaire royal du XVIe siècle. Cette découverte a permis la collecte de matériel directement liée à la fabrication monétaire. Le corpus exceptionnel rassemblé est l’objet d’une étude qui vise à mettre en évidence la chaîne opératoire de fabrication de monnaie à l’époque considérée. Un intérêt particulier est porté à une technique d’argenture qui intervient avant la frappe des monnaies, le blanchiment des flans. Bien documenté pour les périodes antiques, le matériel de La Rochelle offre la possibilité de mettre en évidence ce procédé pour une période plus récente et dans un cadre officiel. De plus, à partir d’expériences de reconstitution, il a été possible de proposer un mécanisme réactionnel. Les hypothèses proposées permettent alors de dégager des implications historiques dans le procédé de fabrication.

Viral kinetics of Enterovirus 71 in human abdomyosarcoma cells

Science.gov (United States)

Lu, Jing; He, Ya-Qing; Yi, Li-Na; Zan, Hong; Kung, Hsiang-Fu; He, Ming-Liang

2011-01-01

AIM: To characterise the viral kinetics of enterovirus 71 (EV71). METHODS: In this study, human rhabdomyosarcoma (RD) cells were infected with EV71 at different multiplicity of infection (MOI). After infection, the cytopathic effect (CPE) was monitored and recorded using a phase contrast microscope associated with a CCD camera at different time points post viral infection (0, 6, 12, 24 h post infection). Cell growth and viability were measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay in both EV71 infected and mock infected cells at each time point. EV71 replication kinetics in RD cells was determined by measuring the total intracellular viral RNA with real-time reverse-transcription polymerase chain reaction (qRT-PCR). Also, the intracellular and extracellular virion RNA was isolated and quantified at different time points to analyze the viral package and secretion. The expression of viral protein was determined by analyze the levels of viral structure protein VP1 with Western blotting. RESULTS: EV71 infection induced a significant CPE as early as 6 h post infection (p.i.) in both RD cells infected with high ratio of virus (MOI 10) and low ratio of virus (MOI 1). In EV71 infected cells, the cell growth was inhibited and the number of viable cells was rapidly decreased in the later phase of infection. EV71 virions were uncoated immediately after entry. The intracellular viral RNA began to increase at as early as 3 h p.i. and the exponential increase was found between 3 h to 6 h p.i. in both infected groups. For viral structure protein synthesis, results from western-blot showed that intracellular viral protein VP1 could not be detected until 6 h p.i. in the cells infected at either MOI 1 or MOI 10; and reached the peak at 9 h p.i. in the cells infected with EV71 at both MOI 1 and MOI 10. Simultaneously, the viral package and secretion were also actively processed as the virus underwent rapid replication. The viral package kinetics

Articulation of Medium of Instruction Politics in the Malaysian Chinese Press

Science.gov (United States)

Samuel, Moses; Khan, Mahmud Hasan; Ng, Lee Luan; Cheang, Kin Wai

2014-01-01

In postcolonial multilingual societies, matters of education are deeply rooted in the discourse of ethnicity. In Malaysia, the interface between ethnicity and education is reflected in recent debates on the choice of medium of instruction (MOI). In 2002, the Malaysian government introduced English as MOI by replacing Malay, the national language,…

Journal of Biomedical Investigation - Vol 5, No 1 (2007)

African Journals Online (AJOL)

Chemical and organoleptic evaluation of Moi-moi based on fermented wateryam, Cocoyam, plantain, African yam bean, cowpea, pigeon pea and corn flours · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. US Onoja, 37-43. http://dx.doi.org/10.4314/jbi.v5i1.30421 ...

Nigerian Food Journal - Vol 30, No 2 (2012)

African Journals Online (AJOL)

JO Arawande, OY Ogunyemi. http://dx.doi.org/10.1016/S0189-7241(15)30027-8 ... Effect of Soy Flour and Maize Flour Addition on Phase Separation in Moi- Moi from Soaked Cowpea (Vigna unguiculata) and Cowpea Flour from Different Cowpea Varieties · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT ...

Live yeast culture and monensin in high grain diets for cattle: rumen fermentation and “in situ” degradability Leveduras vivas e monensina em dietas de alto concentrado para bovinos: parâmetros ruminais e degradabilidade "in situ"

Directory of Open Access Journals (Sweden)

José Carlos Machado Nogueira Filho

2010-03-01

Full Text Available Live yeast cultures have been used as an alternative to replace antibiotics in diets for ruminants. Therefore, the aim was to evaluate the effects of adding live yeast culture (Saccharomyces cerevisiae, Beef Sacc®, Alltech, Inc., monensin (Rumensin®, Elanco, Inc. and the combination of both additives in high grain diets, on rumen fermentation patterns, protozoa organisms and in situ degradability of diet components. Four rumen-cannulated steers were fed a basal ration (2.8Mcal ME/kg DM, 14% CP and submitted to one of four treatments following a 4x4 Latin Square design: control (CON, no additives, yeast (YEA, 0.6g/kg of dry matter, monensin (MON, 0.3g/kg of dry matter and monensin plus yeast (MON+YEA. After 14 days of diet adaptation, the rumen fermentation parameters, the protozoa numbers and the degradation kinetics of corn (CO, soybean meal (SM and soybean hulls (SH were assessed. Feed additives did not affect rumen pH, butirate and ammonia nitrogen concentrations, but decreased total short chain fatty acids (mM. MON and MON+ YEA decreased acetate (% and acetate:propionate ratio whereas propionate was increased by MON and MON+YEA at all sampling times, and by YEA at 4 and 6h post-feeding only. YEA increased the number of protozoa whereas MON and MON+YEA inhibited those microorganisms (total organisms [x104/mL]. There were no effects of YEA and MON+YEA on in situ degradability parameters of any evaluated feed, however, MON increased NDF degradation rate of SH. Monensin effects on rumen fermentation are more significant than those observed when feeding live yeast cultures, and the combination of both additives does not improve their effects.Leveduras têm sido utilizadas para substituir antibióticos em dietas para ruminantes. Assim, objetivou-se avaliar o efeito de leveduras vivas (Saccharomyces cerevisiae, Beef-Sacc®, Alltech, Inc., monensina (Rumensin®, Elanco, Inc. e a combinação de ambos em dietas com alto concentrado, sobre a

Stability, occurence and step morphology of polymorphs and polytypes of stearic acid. II. Mono-lamella step morphology and composite polymorphic/polytypic transformation

Science.gov (United States)

Inaoka, Kimio; Kobayashi, Masamichi; Okada, Masakazu; Sato, Kiyotaka

1988-02-01

Surface step morphology of three structural modifications of stearic acid, B(mon), B(orth II) and C(mon), was observed by replica method (TEM). The characteristic simple and interlaced patterns were observed for monoclinic and pseudo-orthorhombic polytypes, respectively. The observation on the C crystals which were transformed from B(orth II) or B(mon) enabled to detect two different modes of lattice displacement involved in composite polymorphic-polytypic transformations from B to C. B(mon) → C(mon) was found to be caused by a collective inclination of the molecules within the lamellar plane followed by the deformation of the subcell of the aliphatic chain, keeping the symmetry-axis unchanged. In contrast, B(orth II) → C(mon) occurs via an alternate rotation of the long-chain molecules in the adjacent lamellae around the c-axis of B(orth II) prototype, keeping the subcell arrangements unchanged. This means that the polytypic structure of a double-layer type was not preserved during the composite B(orth II) → C(mon) transformation. This peculiarity was discussed in terms of the interlamellar instability of a postulated double-layered polytype of the C polymorph.

Infrared spectroscopic study of polytypic effects on the crystal-growth mechanism of n-hexatriacontane (n-C36H74)

Science.gov (United States)

Kubota, Hideki; Kaneko, Fumitoshi; Kawaguchi, Tatsuya; Kawasaki, Masatsugu

2005-10-01

The solution-crystallization mechanism was investigated for two polytypes in the M011 modification of n-hexatriacontane (n-C36H74), single-layered structure Mon, and double-layered one Orth II. The crystal growth under controlled supersaturation was followed with a micro- Fourier-transform-infrared spectrometer equipped with an optical system for oblique transmission measurements. Supersaturation dependence of growth behavior was significantly different between Mon and Orth II. Although the Mon crystal continued growing at a supersaturation of 0.27, the overgrowth of Orth II on the (001) face of the Mon crystal was confirmed at supersaturations below 0.21. Such a polytypic transformation was not observed for the Orth II crystal at any supersaturation below 0.30. The growth rate of Mon showed a quadratic dependence on supersaturation, while that of Orth II was approximately linear, suggesting spiral growth and two-dimensional-nucleation mechanisms for Mon and Orth II, respectively.

Duean sip, théâtre de l’ethnorégionalisme sud. Les nomades de la mer et le cycle rituel du dixième mois dans la province de Phang Nga (sud de la Thaïlande) Duean sip, Theater of the Southern Ethnoregionalism. The Sea Nomads and the Tenth Lunar Month Ritual Complex in the Phang Nga Province (Southern Thailand)

OpenAIRE

Olivier Ferrari

2012-01-01

La cérémonie bouddhique du dixième mois lunaire, connue comme la fête des morts et des revenants, revêt dans la région de Phang Nga, au sud de la Thaïlande une importance et un rôle qui vont bien au-delà de sa signification religieuse. Il s’agit en effet d’un complexe rituel qui, en s’emboîtant avec les cérémonies du festival végétarien des Sino-Thaïs et avec d’autres cérémonies propres aux nomades de la mer (Moken, Moklen et Urak Lawoi), met en scène les fondements des relations interethniqu...

Plurilingual Pedagogical Practices in a Policy-Constrained Context: A Northern Ugandan Case Study

Science.gov (United States)

Abiria, Doris Maandebo; Early, Margaret; Kendrick, Maureen

2013-01-01

Uganda is a linguistically diverse nation where plurilingualism is common. Its language education policy dictates that, except in large urban areas, one local language be selected as the medium of instruction (MoI), to Primary 3, transitioning to English MoI, in Primary 4. Yet, as Ramanathan and Morgan ([Ramanathan, V., 2007]) argue, "the…

Improving the Effectiveness of English as a Medium of Instruction in Sub-Saharan Africa

Science.gov (United States)

Clegg, John; Simpson, John

2016-01-01

Most academic discussion on the role of language in education in sub-Saharan Africa (SSA) supports the extended use of African languages as media of instruction (MoI), while most practice preserves a monolingual role for European languages. Many ministries of education maintain the belief that African languages are not appropriate as MoIs beyond…

Ideology, Linguistic Capital and the Medium of Instruction in Hong Kong.

Science.gov (United States)

Morrison, Keith; Lui, Icy

2000-01-01

Examines the links between linguistic capital, cultural capital, linguistic imperialism, and the use of English as the medium of instruction (MOI) in Hong Kong. Suggests that the notion of linguistic imperialism in Hong Kong is superceded by the notion of linguistic capital, although neither presents a complete analysis of the MOI issue in Hong…

Effect of Bacteriophages on the Growth of Flavobacterium psychrophilum and Development of Phage-Resistant Strains

DEFF Research Database (Denmark)

Christiansen, Rói Hammershaimb; Madsen, Lone; Dalsgaard, Inger

2016-01-01

The controlling effect of single and multiple phages on the density of Flavobacterium psychrophilum at different initial multiplicity of infection (MOI) was assessed in batch cultures to explore the potential for phage-based treatment of this important fish pathogen. A high initial phage concentr......The controlling effect of single and multiple phages on the density of Flavobacterium psychrophilum at different initial multiplicity of infection (MOI) was assessed in batch cultures to explore the potential for phage-based treatment of this important fish pathogen. A high initial phage...... concentration (MOI = 0.3–4) was crucial for efficient viral lysis, resulting in a 104–105-fold reduction of phage-sensitive cells (both single phages and phage cocktails), which was maintained throughout the incubation (>10 days). Following cell lysis, regrowth of phage-resistant strains was examined...... and resistant strains were isolated for further characterization. The application of a mathematical model allowed simulation of phage-host interactions and resistance development, confirming indications from strain isolations that phage-sensitive strains dominated the regrowing population (>99.8 %) at low MOI...

El gusto por la obra de Tiziano dentro de los círculos de poder en en el norte de España en la segunda mitad del siglo XVI. El ejemplo de los flamencos trabajando “a la italiana”: Gillis Goignet y el taller de Pablo Schepers y Rolan de Mois

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Ana Diéguez Rodríguez

2017-06-01

Full Text Available La influencia de Tiziano en los pintores europeos del siglo XVI es bien conocida. La ejercida sobre los pintores españoles siempre se ha asumido como de forma directa debido a las obras de su mano hechas para la corte. Sin embargo, no sólo va a ser a través de las obras del maestro de Cadore y las copias, tanto italianas como las hechas en territorio peninsular, las que van a influir en el gusto por sus composiciones, sino también a través de las copias hechas por pintores flamencos que llegan a la península. Muchas de estas obras flamencas siguiendo a Tiziano han sido admiradas como originales, y otras han sido demandadas a estos pintores septentrionales debido a su cuidado en el detalle y su capacidad de reproducción. Aquí analizamos dos ejemplos de este tipo, el primero se trata de una Magdalena de Gillis Coignet que estuvo atribuida al italiano, y el segundo la labor como copistas de Tiziano de Pablo Schepers y Roland de Moys en el entorno del duque de Villahermosa. Titian's influence in European painters of the sixteenth century is well known. The influence exerted on Spanish painters has always been assumed as directly because of the works of his hand made for the court. However, it will not only be through that works of the master of Cadore and his copies, as much Italians than those made in peninsular territory, which are going to have influence over the taste for his compositions, but also through copies made by Flemish painters who arrived at the peninsula. Many of these Flemish works following Tiziano´s compositions have been admired as originals, and others have been asked for them to these northern painters because of their care in details and their reproductive skills. This article analyzes two examples of both types, the first one is a Mary Magdalen by Gillis Coignet that was attributed to the Italian painter, and the second the work as copyists of Titian by Pablo Schepers and Rolan de Mois in the milieu of the Duke of

KONE ET AL.pmd

African Journals Online (AJOL)

SECRETARIAT

21 feuilles. Pour les plants âgés de 7 mois, le nombre de rejets a été de 13, avec une émission de 27 feuilles. ... l'organisation de la filière. Aussi .... To : les plantes à la récolte ; M.A.P. : Mois Après mise en Plantation (Moyenne ± erreur type).

Microbiological and Physicochemical analysis of African yam bean ...

African Journals Online (AJOL)

Microbiological and Physicochemical analysis of African yam bean Moi Moi stored at. D. O. DOSUNMU, H. O. NJOKU. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · http://dx.doi.org/10.4314/gjpas.v7i4.16296 · AJOL African Journals Online. HOW TO USE ...

Effects of sulfur and monensin concentrations on in vitro dry matter disappearance, hydrogen sulfide production, and volatile fatty acid concentrations in batch culture ruminal fermentations.

Science.gov (United States)

Smith, D R; Dilorenzo, N; Leibovich, J; May, M L; Quinn, M J; Homm, J W; Galyean, M L

2010-04-01

Effects of monensin (MON) and S on in vitro fermentation and H(2)S production were evaluated in 2 experiments. In Exp. 1, 2 ruminally cannulated steers were adapted (>14 d) to a 75% concentrate diet [steam-flaked corn (SFC)-based], and ruminal fluid was collected approximately 4 h after feeding. Substrate composed (DM basis) of 85.2% SFC, 9% alfalfa hay, 5% cottonseed meal, and 0.8% urea was added with ruminal fluid and buffer to sealed 125-mL serum bottles to allow for gas collection. A Na(2)SO(4) solution was added to yield S equivalent to 0.2, 0.4, and 0.8% of substrate DM, and MON was included at 0, 2, 4, and 6 mg/L of culture volume. Bottle head-space gas was analyzed for H(2)S. No MON (P = 0.29) or MON x S interaction (P = 0.41) effects were detected for H(2)S production. Increasing S linearly increased (P molar proportions of acetate, butyrate, and the acetate:propionate ratio (A:P), and linearly increased (P 21 d) to a 75% concentrate diet (SFC base) that contained 15% (DM basis) wet corn distillers grains plus solubles (WDGS) and MON at 22 mg/kg of DM. In vitro substrate DM was composed of 75.4% SFC, 15% WDGS, 9% alfalfa hay, and 0.6% urea, and S and MON concentrations were the same as in Exp. 1. No effects of MON (P = 0.93) or the MON x S interaction (P = 0.99) were noted for H(2)S production; however, increasing S linearly increased (P molar proportions of acetate, butyrate, and A:P and linearly increased (P molar proportions were evident with MON regardless of S concentration.

Érasme, l'Europe et moi.

Directory of Open Access Journals (Sweden)

Jacques Lévy

2003-03-01

Full Text Available Ce film est fondé sur une double métaphore, poussée jusqu'à l'allégorie : la diversité de l'Europe comme expression de celle de l'individu, la construction européenne comme image de la construction de la personnalité. Passant un an à Barcelone dans le cadre d'échanges « Erasmus », un étudiant français découvre, en partageant un appartement avec des étudiants venus de plusieurs pays européens, l'importance de l'altérité dans la création ...

Moi drug M.G. / Viktor Pivovarov

Index Scriptorium Estoniae

Pivovarov, Viktor

2002-01-01

Vene kunstnik Viktor Pivovarov meenutab ühiseid kunstiõpinguid oma sõbra Mihhail Gorbatshoviga Moskvas Juri Georgijevitsh Gushtshini stuudios, kirjeldab Mihhail Gorbatshovi loomingut, tööde eksponeerimist rühmituse "Jauza" näitusel ja seda, kuidas poliitik tõrjus lõpuks kunstniku temas tahaplaanile. Mihhail Gorbatshovi tööd on hoiul Viktor Pivovarovi käes - lahkudes Tshehhoslovakkiasse viis ta need kaasa

Language, Education and Linguistic Human Rights in Ghana | Owu ...

African Journals Online (AJOL)

This paper uses both primary and secondary sources to argue that the current language policy violates the Linguistic Human Rights (LHR) of the Ghanaian child. To end this violation, the paper argues for the addition of more L1s as MoI, the cultivation of a positive attitude towards the use of L1 as MoI, the constitutional ...

Madame Kara Walker, notre artiste

Directory of Open Access Journals (Sweden)

Riché Deianne Richardson

2008-01-01

Full Text Available « Mon Ennemi, Mon Frère, Mon Bourreau, Mon Amour, » the epic exhibition at ARC/ Musée d’art moderne de la ville de Paris running from 20 June to 9 September, reveals the creative genius and vision of the artist Kara Walker, who was born in Stockton, California in 1969. The show is her most comprehensive one yet in Europe and includes the form that Walker has uniquely developed and for which she is best known, cut-out black silhouettes that are sometimes small and at other times gigantic and r...

Information Meeting on credit on landed property in France

CERN Multimedia

Messonier; Petit

1972-01-01

Accession à la propriété- Mons.Comte représente ce groupe de travail au sein du comité des affaires sociales et présente les invités: Mons.Messonier, directeur départemental pour l'Ain et le Jura du Crédit Foncier Français Mons.Frelon, directeur au Crédit Foncier à Annecy Mon.Petit, directeur régional du Comptoir des Entrepreneurs à Lyon Ces 3 personnes nous communiquent des informations importantes et nouvelles dispositions. Ils parlent du regime actuel des prix et prêts à la construction en France

Flank tectonics of Martian volcanoes

International Nuclear Information System (INIS)

Thomas, P.J.; Squyres, S.W.; Carr, M.H.

1990-01-01

On the flanks of Olympus Mons is a series of terraces, concentrically distributed around the caldera. Their morphology and location suggest that they could be thrust faults caused by compressional failure of the cone. In an attempt to understand the mechanism of faulting and the possible influences of the interior structure of Olympus Mons, the authors have constructed a numerical model for elastic stresses within a Martian volcano. In the absence of internal pressurization, the middle slopes of the cone are subjected to compressional stress, appropriate to the formation of thrust faults. These stresses for Olympus Mons are ∼250 MPa. If a vacant magma chamber is contained within the cone, the region of maximum compressional stress is extended toward the base of the cone. If the magma chamber is pressurized, extensional stresses occur at the summit and on the upper slopes of the cone. For a filled but unpressurized magma chamber, the observed positions of the faults agree well with the calculated region of high compressional stress. Three other volcanoes on Mars, Ascraeus Mons, Arsia Mons, and Pavonis Mons, possess similar terraces. Extending the analysis to other Martian volcanoes, they find that only these three and Olympus Mons have flank stresses that exceed the compressional failure strength of basalt, lending support to the view that the terraces on all four are thrust faults

Towards a multiconfigurational method of increments

Science.gov (United States)

Fertitta, E.; Koch, D.; Paulus, B.; Barcza, G.; Legeza, Ö.

2018-06-01

The method of increments (MoI) allows one to successfully calculate cohesive energies of bulk materials with high accuracy, but it encounters difficulties when calculating dissociation curves. The reason is that its standard formalism is based on a single Hartree-Fock (HF) configuration whose orbitals are localised and used for the many-body expansion. In situations where HF does not allow a size-consistent description of the dissociation, the MoI cannot be guaranteed to yield proper results either. Herein, we address the problem by employing a size-consistent multiconfigurational reference for the MoI formalism. This leads to a matrix equation where a coupling derived by the reference itself is employed. In principle, such an approach allows one to evaluate approximate values for the ground as well as excited states energies. While the latter are accurate close to the avoided crossing only, the ground state results are very promising for the whole dissociation curve, as shown by the comparison with density matrix renormalisation group benchmarks. We tested this two-state constant-coupling MoI on beryllium rings of different sizes and studied the error introduced by the constant coupling.

Air ambulance tasking: mechanism of injury, telephone interrogation or ambulance crew assessment?

Science.gov (United States)

Wilmer, Ian; Chalk, Graham; Davies, Gareth Edward; Weaver, Anne Elizabeth; Lockey, David John

2015-10-01

The identification of serious injury is critical to the tasking of air ambulances. London's Air Ambulance (LAA) is dispatched by a flight paramedic based on mechanism of injury (MOI), paramedical interrogation of caller (INT) or land ambulance crew request (REQ).This study aimed to demonstrate which of the dispatch methods was most effective (in accuracy and time) in identifying patients with serious injury. A retrospective review of 3 years of data (to December 2010) was undertaken. Appropriate dispatch was defined as the requirement for LAA to escort the patient to hospital or for resuscitation on-scene. Inaccurate dispatch was where LAA was cancelled or left the patient in the care of the land ambulance crew. The χ(2) test was used to calculate p values; with significance adjusted to account for multiple testing. There were 2203 helicopter activations analysed: MOI 18.9% (n=417), INT 62.4% (n=1375) and REQ 18.7% (n=411). Appropriate dispatch rates were MOI 58.7% (245/417), INT 69.7% (959/1375) and REQ 72.2% (297/411). INT and REQ were both significantly more accurate than MOI (pinterrogation of the caller by a flight paramedic is as accurate as ground ambulance crew requests, and both are significantly better than MOI in identifying serious injury. Overtriage remains an issue with all methods. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Case report

African Journals Online (AJOL)

raoul

10 avr. 2012 ... (retrouvaient Mycobacterium tuberculosis. Une chimiothérapie antituberculeuse a été administrée pendant 12 mois. À 24 mois, la patiente ne présentait pas de récidive mais une arthropathie dégénérative secondaire subtalienne. Il nous semble intéressant de rappeler que tout tableau clinique traînant ou ...

2741-IJBCS-Proof-Njoyim Estella Buleng T

African Journals Online (AJOL)

hp

Néanmoins, le chrome et fer étaient fortement concentrés dans presque tous les échantillons au mois de janvier (0,14 à ...... d'eau, augmentant ainsi les infections observées en ces mois. Ce cycle résulte en l'occurrence des infections d'origine hydrique tout au long de l'année. Conclusion. A l'issue des analyses physiques,.

Phenotypic mixing and hiding may contribute to memory in viral quasispecies

Directory of Open Access Journals (Sweden)

Novella Isabel S

2003-06-01

Full Text Available Abstract Background In a number of recent experiments with food-and-mouth disease virus, a deleterious mutant, RED, was found to avoid extinction and remain in the population for long periods of time. Since RED characterizes the past evolutionary history of the population, this observation was called quasispecies memory. While the quasispecies theory predicts the existence of these memory genomes, there is a disagreement between the expected and observed mutant frequency values. Therefore, the origin of quasispecies memory is not fully understood. Results We propose and analyze a simple model of complementation between the wild type virus and a mutant that has an impaired ability of cell entry, the likely cause of fitness differences between wild type and RED mutants. The mutant will go extinct unless it is recreated from the wild type through mutations. However, under phenotypic mixing-and-hiding as a mechanism of complementation, the time to extinction in the absence of mutations increases with increasing multiplicity of infection (m.o.i.. If the RED mutant is constantly recreated by mutations, then its frequency at equilibrium under selection-mutation balance also increases with increasing m.o.i. At high m.o.i., a large fraction of mutant genomes are encapsidated with wild-type protein, which enables them to infect cells as efficiently as the wild type virions, and thus increases their fitness to the wild-type level. Moreover, even at low m.o.i. the equilibrium frequency of the mutant is higher than predicted by the standard quasispecies model, because a fraction of mutant virions generated from wild-type parents will also be encapsidated by wild-type protein. Conclusions Our model predicts that phenotypic hiding will strongly influence the population dynamics of viruses, particularly at high m.o.i., and will also have important effects on the mutation-selection balance at low m.o.i. The delay in mutant extinction and increase in mutant

Oxidative metabolism of monensin in rat liver microsomes and interactions with tiamulin and other chemotherapeutic agents: evidence for the involvement of cytochrome P-450 3A subfamily.

Science.gov (United States)

Nebbia, C; Ceppa, L; Dacasto, M; Carletti, M; Nachtmann, C

1999-09-01

Monensin (MON) is an ionophore antibiotic widely used in veterinary practice as a coccidiostatic or a growth promoter. The aims of this study were to characterize the P-450 isoenzyme(s) involved in the biotransformation of the ionophore and to investigate how this process may be affected by tiamulin and other chemotherapeutic agents known to produce toxic interactions with MON when administered concurrently in vivo. In liver microsomes from untreated rats (UT) or from rats pretreated, respectively, with ethanol (ETOH), beta-naphthoflavone (betaNAF), phenobarbital (PB), pregnenolone 16alpha-carbonitrile (PCN), or dexamethasone (DEX), the rate of MON O-demethylation was the following: DEX > PCN > PB > UT = ETOH > betaNAF; similar results were obtained by measuring total MON metabolism. In addition, the extent of triacetyloleandomycin-mediated P-450 complexes was greatly reduced by the prior addition of 100 microM MON. In DEX-treated microsomes, MON O-demethylation was found to fit monophasic Michaelis-Menten kinetics (K(M) = 67.6 +/- 0.01 microM; V(max) = 4.75 +/- 0.76 nmol/min/mg protein). Tiamulin markedly inhibited this activity in an apparent competitive manner, with a calculated K(i) (Dixon plot) of 8.2 microM and an IC(50) of about 25 microM. At the latter concentration, only ketoconazole or metyrapone, which can bind P-450 3A, inhibited MON O-demethylase to a greater extent than tiamulin, whereas alpha-naphthoflavone, chloramphenicol, or sulphametasine was less effective. These results suggest that P-450 3A plays an important role in the oxidative metabolism of MON and that compounds capable of binding or inhibiting this isoenzyme could be expected to give rise to toxic interactions with the ionophore.

Effects of a combination of plant bioactive lipid compounds and biotin compared with monensin on body condition, energy metabolism and milk performance in transition dairy cows

Science.gov (United States)

Hausmann, Janis; Deiner, Carolin; Patra, Amlan K.; Immig, Irmgard; Starke, Alexander

2018-01-01

The aim of this study was to test whether a combination of plant bioactive lipid compounds (also termed ‘essential oils’) and biotin (PBLC+B) could decrease the mobilization of body reserves and ketosis incidence in postpartum dairy cows. We compared non-supplemented control (CON) cows with cows receiving monensin (MON) as a controlled-release capsule at d -21, and with cows receiving PBLC+B from day (d) -21 before calving until calving (Phase 1) and further until d 37 after calving (Phase 2), followed by PBLC+B discontinuation from d 38 to d 58 (Phase 3). The PBLC+B cows had higher body weight and higher back fat thickness than CON cows and lesser body weight change than MON and CON cows in Phase 3. Body condition score was not different among groups. Milk protein concentration tended to be higher on the first herd test day in PBLC+B vs. CON cows. Milk fat concentration tended to be highest in PBLC+B cows throughout Phases 2 and 3, with significantly higher values in PBLC+B vs. MON cows on the second herd test day. Yields of energy-corrected milk were higher in PBLC+B vs. CON and MON cows in Phase 2 and higher in PBLC+B and MON cows vs. CON cows in Phase 3. The incidence of subclinical ketosis was 83%, 61% and 50% in CON, PBLC+B and MON cows, respectively, with lower mean β-hydroxybutyrate values in MON than in PBLC+B cows in Phase 1 prepartum. The serum triglyceride concentration was higher in PBLC+B vs. CON cows on d 37. No differences were observed in serum glucose, urea, non-esterified fatty acids, cholesterol and bilirubin concentrations. Aspartate transaminase and γ-glutamyltranspeptidase but not glutamate dehydrogenase activities tended to be highest in MON and lowest in PBLC+B in Phase 2. We conclude that PBLC+B prevent body weight loss after parturition and are associated with similar ketosis incidence and partly higher yields of energy-corrected milk compared to MON supplementation of dairy cows. PMID:29584764

Particle size distribution properties in mixed-phase monsoon clouds from in situ measurements during CAIPEEX

Science.gov (United States)

Patade, Sachin; Prabha, T. V.; Axisa, D.; Gayatri, K.; Heymsfield, A.

2015-10-01

A comprehensive analysis of particle size distributions measured in situ with airborne instrumentation during the Cloud Aerosol Interaction and Precipitation Enhancement Experiment (CAIPEEX) is presented. In situ airborne observations in the developing stage of continental convective clouds during premonsoon (PRE), transition, and monsoon (MON) period at temperatures from 25 to -22°C are used in the study. The PRE clouds have narrow drop size and particle size distributions compared to monsoon clouds and showed less development of size spectra with decrease in temperature. Overall, the PRE cases had much lower values of particle number concentrations and ice water content compared to MON cases, indicating large differences in the ice initiation and growth processes between these cloud regimes. This study provided compelling evidence that in addition to dynamics, aerosol and moisture are important for modulating ice microphysical processes in PRE and MON clouds through impacts on cloud drop size distribution. Significant differences are observed in the relationship of the slope and intercept parameters of the fitted particle size distributions (PSDs) with temperature in PRE and MON clouds. The intercept values are higher in MON clouds than PRE for exponential distribution which can be attributed to higher cloud particle number concentrations and ice water content in MON clouds. The PRE clouds tend to have larger values of dispersion of gamma size distributions than MON clouds, signifying narrower spectra. The relationships between PSDs parameters are presented and compared with previous observations.

Métodos alternativos para a detecção de pirogênios em produtos e ambientes sujeitos a Vigilância Sanitária: avanços e perspectivas no Brasil a partir do reconhecimento internacional do Teste de Ativação de Monócitos

Directory of Open Access Journals (Sweden)

Cristiane Caldeira da Silva

2018-02-01

Full Text Available Introdução: A detecção de pirogênios é imprescindível no controle da qualidade de produtos injetáveis. O Teste de Pirogênio em coelhos ainda tem larga aplicação, apesar da existência de métodos alternativos como o Teste de Ativação de Monócitos (MAT. Objetivo: Revisar o uso dos métodos alternativos no teste de pirogênio, apontando avanços e perspectivas a partir do reconhecimento do MAT pela Farmacopeia Europeia e sua aceitação para fins regulatórios no Brasil. Método: Uma busca foi realizada nas bases PubMed e BVS, com posterior classificação, categorização por assuntos e análise crítica dos resultados. Resultados: Foram identificados 24 trabalhos, abordando temas como as aplicações do MAT, sua validação e comparação com testes in vivo. O MAT apresentou melhores resultados quando comparado a outros testes, tanto na avaliação de produtos biológicos como na detecção de pirogênios não-endotoxinas. Limitações para sua difusão incluem a dificuldade de obtenção de sangue total humano como fonte de monócitos, para o qual diversas alternativas têm sido propostas. Conclusões: O MAT se mostra um método promissor, com aplicação na avaliação da segurança de novas tecnologias. Sua aplicação no Brasil depende de uma política nacional de implantação, que inclua maior Integração entre BraCVAM, Concea e RENAMA na busca por seu reconhecimento para fins regulatórios.

898-IJBCS-Article- Prof Jean Marc A

African Journals Online (AJOL)

DR GATSING

moyenne avec un écart thermique ne dépassant pas 3,2 °C entre les mois le plus chaud et le mois le moins froid. Méthodologie. L'étude a été conduite en deux ..... saison pluvieuse et le simple séchage des fourrages verts permet selon Mensah et Ekué. (2003) de réduire leur importance. Par ailleurs, les OPG de Coccidies ...

Cancers de la prostate de score de Gleason supérieur ou égal à 8 ...

African Journals Online (AJOL)

B. Sine

13,18 mois. La survie globale de la série à 6, 12, et 24 mois était respectivement de 72,7; 54,5 et 0,9%. La ..... n'est pas un outil de dépistage approprié pour le diagnostic précoce du cancer de ... patients ainsi que la réalisation de la technique de prostatectomie radicale. ... concernant tous les sujets de recherche. Consent ...

Trente années qui ébranlèrent la physique histoire de la théorie quantique

CERN Document Server

Gamow, George

1968-01-01

G. Gamow, dans cet ouvrage, déploie une fois encore ses qualités d'historien, de vulgarisateur et d'homme d'esprit. L'"histoire de la théorie quantique" raconte la naissance de la physique moderne au cours des trente premières années du siècle, en nous guidant ainsi à travers cette galerie de portraits où les grands noms de la physique sont présentés, par les textes, les photographies et les croquis, sous leur aspect le moins académique.

Maternal fish oil supplementation in lactation: Effect on visual acuity and n-3 fatty acid content of infant erythrocytes

DEFF Research Database (Denmark)

Lauritzen, L.; Jørgensen, M.H.; Mikkelsen, T.B.

2004-01-01

of fish oil (FO) supplements in lactating mothers. In this double-blinded randomized trial, Danish mothers with habitual fish intake below the 50th percentile of the Danish National Birth Cohort were randomized to microencapsulated FO [1.3 g/d long-chain n-3 FA (n-3 LCPUFA)] or olive oil (00......). The intervention started within a week after delivery and lasted 4 mon. Mothers with habitual high fish intake and their infants were included as a reference group. Ninety-seven infants completed the trial (44 OO-group, 53 FO-group) and 47 reference infants were followed up. The primary outcome measures were: DHA...... content of milk samples (0, 2, and 4 mon postnatal) and of infant red blood cell (RBC) membranes (4 mon postnatal), and infant visual acuity (measured by swept visual evoked potential at 2 and 4 mon of age). FO supplementation gave rise to a threefold increase in the DHA content of the 4-mon milk samples...

Single-Event Transgene Product Levels Predict Levels in Genetically Modified Breeding Stacks.

Science.gov (United States)

Gampala, Satyalinga Srinivas; Fast, Brandon J; Richey, Kimberly A; Gao, Zhifang; Hill, Ryan; Wulfkuhle, Bryant; Shan, Guomin; Bradfisch, Greg A; Herman, Rod A

2017-09-13

The concentration of transgene products (proteins and double-stranded RNA) in genetically modified (GM) crop tissues is measured to support food, feed, and environmental risk assessments. Measurement of transgene product concentrations in breeding stacks of previously assessed and approved GM events is required by many regulatory authorities to evaluate unexpected transgene interactions that might affect expression. Research was conducted to determine how well concentrations of transgene products in single GM events predict levels in breeding stacks composed of these events. The concentrations of transgene products were compared between GM maize, soybean, and cotton breeding stacks (MON-87427 × MON-89034 × DAS-Ø15Ø7-1 × MON-87411 × DAS-59122-7 × DAS-40278-9 corn, DAS-81419-2 × DAS-44406-6 soybean, and DAS-21023-5 × DAS-24236-5 × SYN-IR102-7 × MON-88913-8 × DAS-81910-7 cotton) and their component single events (MON-87427, MON-89034, DAS-Ø15Ø7-1, MON-87411, DAS-59122-7, and DAS-40278-9 corn, DAS-81419-2, and DAS-44406-6 soybean, and DAS-21023-5, DAS-24236-5, SYN-IR102-7, MON-88913-8, and DAS-81910-7 cotton). Comparisons were made within a crop and transgene product across plant tissue types and were also made across transgene products in each breeding stack for grain/seed. Scatter plots were generated comparing expression in the stacks to their component events, and the percent of variability accounted for by the line of identity (y = x) was calculated (coefficient of identity, I 2 ). Results support transgene concentrations in single events predicting similar concentrations in breeding stacks containing the single events. Therefore, food, feed, and environmental risk assessments based on concentrations of transgene products in single GM events are generally applicable to breeding stacks composed of these events.

Field-evolved resistance to Cry1Ab maize by Spodoptera frugiperda in Brazil.

Science.gov (United States)

Omoto, Celso; Bernardi, Oderlei; Salmeron, Eloisa; Sorgatto, Rodrigo J; Dourado, Patrick M; Crivellari, Augusto; Carvalho, Renato A; Willse, Alan; Martinelli, Samuel; Head, Graham P

2016-09-01

The first Bt maize in Brazil was launched in 2008 and contained the MON 810 event, which expresses Cry1Ab protein. Although the Cry1Ab dose in MON 810 is not high against fall armyworm (FAW), Spodoptera frugiperda (J.E. Smith), MON 810 provided commercial levels of control. To support insect resistance management in Brazil, the baseline and ongoing susceptibility of FAW was examined using protein bioassays, and the level of control and life history parameters of FAW were evaluated on MON 810 maize. Baseline diet overlay assays with Cry1Ab (16 µg cm(-2) ) caused 76.3% mortality to field FAW populations sampled in 2009. Moderate mortality (48.8%) and significant growth inhibition (88.4%) were verified in leaf-disc bioassays. In greenhouse trials, MON 810 had significantly less damage than non-Bt maize. The surviving FAW larvae on MON 810 (22.4%) had a 5.5 day increase in life cycle time and a 24% reduction in population growth rate. Resistance monitoring (2010-2015) showed a significant reduction in Cry1Ab susceptibility of FAW over time. Additionally, a significant reduction in the field efficacy of MON 810 maize against FAW was observed in different regions from crop season 2009 to 2013. The decrease in susceptibility to Cry1Ab was expected, but the specific contributions to this resistance by MON 810 maize cannot be distinguished from cross-resistance to Cry1Ab caused by exposure to Cry1F maize. Technologies combining multiple novel insecticidal traits with no cross-resistance to the current Cry1 proteins and high activity against the same target pests should be pursued in Brazil and similar environments. © 2015 Society of Chemical Industry. © 2015 Society of Chemical Industry.

Nye oplysninger om effekter af Bt-majs på sommerfugle. MON810, BT11. Brev fra Greenpeace til Miljøministeren. Modtaget 17-12-2004, deadline 22-12-2004, svar 22-12-2004

DEFF Research Database (Denmark)

Strandberg, Morten Tune; Kjellsson, Gøsta; Damgaard, Christian

2012-01-01

"De nye oplysninger medfører ingen væsentlige ændringer af DMUs tidligere risikovurdering af Bt-11 majsen (C/F/96.05.10, mail pr. 28-08-2003). Dog har vi en tilføjelse vedrørende behov for specifik overvågning (se nedenfor). Vi har ikke tidligere foretaget nogen konkret risikovurdering af MON810...... arters fortsatte forekomst. Derfor har DMU ved tidligere risikovurdering af Bt-majslinier til dyrkning (majslinie 1507 og Bt-11) foreslået at der indføres en 5 m dyrkningsfri bufferzone til naturhabitater hvor larver af truede/sjældne sommerfugle findes. En andet virkemiddel kunne være at omgive randen...... af Bt-majsmarker med et værnebælte af konventionel majs. På grund af den usikkerhed der findes på området vil det indtil der foreligger et bedre vidensgrundlag være relevant med en specifik overvågning af truede eller sjældne sommerfuglearter hvor der er habitater for disse i nærheden af Bt...

Polytypism in n-fatty acids and low-frequency Raman spectra: Stearic acid B form

Science.gov (United States)

Kobayashi, Masamichi; Kobayashi, Tohru; Itoh, Yuzo; Sato, Kiyotaka

1984-03-01

Single crystals of single-layered (mon) and double-layered (orth II) polytypes of stearic acid B form were obtained and their structures were investigated by the x-ray diffraction and vibrational spectroscopic methods. Two polytypes exhibited quite different Raman spectra in the frequency range from 65 to 2 cm-1. The Raman bands appeared as singlets in mon, while they split into doublets with different polarization in orth II through the interlamellar interactions between two successive layers contained in the unit cell. The frequencies of the phonon modes in orth II were found to be lower than the corresponding ones in mon, indicating that orth II (or mon) was the high-temperature (low-temperature) stable form.

Mycotoxin production by Fusarium avenaceum strains isolated from Norwegian grain and the cytotoxicity of rice culture extracts to porcine kidney epithelial cells.

Science.gov (United States)

Morrison, Ellen; Kosiak, Barbara; Ritieni, Alberto; Aastveit, Are H; Uhlig, Silvio; Bernhoft, Aksel

2002-05-08

The secondary metabolites of 24 isolates of Fusarium avenaceum from Norwegian cereals and grown on rice have been characterized. Moniliformin (MON), enniatins (ENNs), and beauvericin (BEA) were analyzed by high-performance liquid chromatography. Porcine kidney epithelial cells (PK15, American Type Culture Collection) were used to study the cytotoxicity of MON in the extracts. The following metabolites were produced by all isolates, ranked by concentration in rice cultures: ENN-B, MON, ENN-B1, and ENN-A. BEA was produced by eight isolates. The productions of BEA and ENN-A were significantly correlated, as was the case with ENN-B and ENN-B1. MON production was correlated neither to any of the other toxins nor to toxicity.

Development of a risk prediction model among professional hockey players with visible signs of concussion.

Science.gov (United States)

Bruce, Jared M; Echemendia, Ruben J; Meeuwisse, Willem; Hutchison, Michael G; Aubry, Mark; Comper, Paul

2017-04-04

Little research examines how to best identify concussed athletes. The purpose of the present study was to develop a preliminary risk decision model that uses visible signs (VS) and mechanisms of injury (MOI) to predict the likelihood of subsequent concussion diagnosis. Coders viewed and documented VS and associated MOI for all NHL games over the course of the 2013-2014 and 2014-2015 regular seasons. After coding was completed, player concussions were identified from the NHL injury surveillance system and it was determined whether players exhibiting VS were subsequently diagnosed with concussions by club medical staff as a result of the coded event. Among athletes exhibiting VS, suspected loss of consciousness, motor incoordination or balance problems, being in a fight, having an initial hit from another player's shoulder and having a secondary hit on the ice were all associated with increased risk of subsequent concussion diagnosis. In contrast, having an initial hit with a stick was associated with decreased risk of subsequent concussion diagnosis. A risk prediction model using a combination of the above VS and MOI was superior to approaches that relied on individual VS and associated MOI (sensitivity=81%, specificity=72%, positive predictive value=26%). Combined use of VS and MOI significantly improves a clinician's ability to identify players who need to be evaluated for possible concussion. A preliminary concussion prediction log has been developed from these data. Pending prospective validation, the use of these methods may improve early concussion detection and evaluation. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Limiting opportunities for cheating stabilizes virulence in insect parasitic nematodes.

Science.gov (United States)

Shapiro-Ilan, David; Raymond, Ben

2016-03-01

Cooperative secretion of virulence factors by pathogens can lead to social conflict when cheating mutants exploit collective secretion, but do not contribute to it. If cheats outcompete cooperators within hosts, this can cause loss of virulence. Insect parasitic nematodes are important biocontrol tools that secrete a range of significant virulence factors. Critically, effective nematodes are hard to maintain without live passage, which can lead to virulence attenuation. Using experimental evolution, we tested whether social cheating might explain unstable virulence in the nematode Heterorhabditis floridensis by manipulating relatedness via multiplicity of infection (MOI), and the scale of competition. Passage at high MOI, which should reduce relatedness, led to loss of fitness: virulence and reproductive rate declined together and all eight independent lines suffered premature extinction. As theory predicts, relatedness treatments had more impact under stronger global competition. In contrast, low MOI passage led to more stable virulence and increased reproduction. Moreover, low MOI lineages showed a trade-off between virulence and reproduction, particularly for lines under stronger between-host competition. Overall, this study indicates that evolution of virulence theory is valuable for the culture of biocontrol agents: effective nematodes can be improved and maintained if passage methods mitigate possible social conflicts.

Transcriptome Analysis Reveals Novel Entry Mechanisms and a Central Role of SRC in Host Defense during High Multiplicity Mycobacterial Infection.

Directory of Open Access Journals (Sweden)

Jay Zhang

Full Text Available Mycobacterium tuberculosis (MTB infects an estimated one-third of the global population and is one of the main causes of mortality from an infectious agent. The characteristics of macrophages challenged by MTB with a high multiplicity of infection (MOI, which mimics both clinical disseminated infection and granuloma formation, are distinct from macrophages challenged with a low MOI. To better understand the cross talk between macrophage host cells and mycobacteria, we compared the transcription patterns of mouse macrophages infected with bacille Calmette-Guérin, H37Ra and M. smegmatis. Attention was focused on the changes in the abundance of transcripts related to immune system function. From the results of a transcriptome profiling study with a high mycobacterial MOI, we defined a pathogen-specific host gene expression pattern. The present study suggests that two integrins, ITGA5 and ITGAV, are novel cell surface receptors mediating mycobacterium entry into macrophages challenged with high MOI. Our results indicate that SRC likely plays a central role in regulating multiple unique signaling pathways activated by MTB infection. The integrated results increase our understanding of the molecular networks behind the host innate immune response and identify important targets that might be useful for the development of tuberculosis therapy.

Diet and diet combined with chronic aerobic exercise decreases body fat mass and alters plasma and adipose tissue inflammatory markers in obese women.

Science.gov (United States)

Lakhdar, Nadia; Denguezli, Myriam; Zaouali, Monia; Zbidi, Abdelkrim; Tabka, Zouhair; Bouassida, Anissa

2013-12-01

The purpose of this study was to investigate the effect of 6 months aerobic exercise and diet alone or in combination on markers of inflammation (MOI) in circulation and in adipose abdominal tissue (AT) in obese women. Thirty obese subjects were randomized into a 24-week intervention: (1) exercise (EX), (2) diet (DI), and (3) exercise and diet (EXD). Blood samples were collected at baseline, after 12 and 24 weeks. AT biopsies were obtained only at baseline and after 24 weeks. In the EXD and DI groups, the fat loss was after 12 weeks was -13.74 and -7.8 % (P exercise was found to have no effects on circulating and AT MOI despite an increased VO2max. Rather important body composition modifications were found to have beneficial effects on circulating and AT MOI in these obese women.

Evaluación de la exposición al monóxido de carbono en vendedores de quioscos. Valencia, Venezuela

Directory of Open Access Journals (Sweden)

Maritza Rojas

2001-04-01

Full Text Available Objetivos. Estudiar la intensidad de la exposición al monóxido de carbono (CO, los factores contribuyentes a esta exposición y sus potenciales efectos sobre la salud en vendedores de quioscos ubicados en una avenida de alta densidad de tránsito en Valencia, Venezuela. Métodos. Se midió la concentración de CO en el aire (CO-aire en 16 quioscos y se determinó la concentración sanguínea de carboxihemoglobina (COHb-S en los individuos que trabajaban en esos quioscos y en un grupo de control formado por docentes, estudiantes y obreros de la Universidad Simón Rodríguez, ubicada en una zona montañosa, apartada, sin contaminación ambiental aparente. Resultados. En el grupo expuesto no se encontró correlación entre las concentraciones de COHb-S y de CO-aire. La COHb-S media del grupo expuesto (2,9% fue significativamente superior a la del grupo de control (1,6% y a la concentración permisible según el método analítico empleado (< 1,5%. Todos los síntomas de frecuencia diaria afectaron a un mayor porcentaje de individuos del grupo expuesto que del grupo de control; entre los de frecuencia diaria, los más comunes en el grupo expuesto fueron la cefalea y la fatiga. En siete quioscos (43,7% se excedieron los límites permisibles de CO-aire. Conclusiones. Aunque la COHb-S media no parece alarmante, las exposiciones al CO registradas podrían tener un impacto adverso sobre la salud de estos trabajadores, especialmente si padecieran una alteración cardiovascular o por el resultado de la acción potenciadora con otros contaminantes ambientales. Se recomienda la realización de nuevos estudios con mediciones más frecuentes y prolongadas, para ejercer medidas de prevención y control de efectos adversos para la salud y estimar la calidad del aire.

Angiomyolipome rénal bilatéral et hémorragique: A propos d\\'un cas ...

African Journals Online (AJOL)

Un mois après, devant la récidive d\\'une hématurie massive avec état de choc hémorragique clinique et biologique, une néphrectomie droite d\\'hémostase était réalisée. L\\'évolution a été favorable et le recul actuel est de 24 mois. Keywords: Angiomyolipome, sclérose tubéreuse de Bourneville, embolisation artérielle ...

SIGAR Special Inspector General For Afghanistan Reconstruction

Science.gov (United States)

2017-07-30

June 2015 weekly NCC status report for the ASOM program listed training statistics and capability ratings for each ANDSF site where NCC conducted...that while the MOI has sig- nificantly improved its fuel consumption reporting, the MOI is delinquent in SIGAR SPECIAL PROJECT SIGAR has an ongoing...must be addressed.516 Eurostat, the statistical office of the EU, reported 12,475 first-time Afghan asylum seekers in the EU in the first three months

Infection of Human Fallopian Tube Epithelial Cells with Neisseria gonorrhoeae Protects Cells from Tumor Necrosis Factor Alpha-Induced Apoptosis

Science.gov (United States)

Morales, Priscilla; Reyes, Paz; Vargas, Macarena; Rios, Miguel; Imarai, Mónica; Cardenas, Hugo; Croxatto, Horacio; Orihuela, Pedro; Vargas, Renato; Fuhrer, Juan; Heckels, John E.; Christodoulides, Myron; Velasquez, Luis

2006-01-01

Following infection with Neisseria gonorrhoeae, bacteria may ascend into the Fallopian tubes (FT) and induce salpingitis, a major cause of infertility. In the FT, interactions between mucosal epithelial cells and gonococci are pivotal events in the pathogen's infection cycle and the inflammatory response. In the current study, primary FT epithelial cells were infected in vitro with different multiplicities of infection (MOI) of Pil+ Opa+ gonococci. Bacteria showed a dose-dependent association with cells and induced the secretion of tumor necrosis factor alpha (TNF-α). A significant finding was that gonococcal infection (MOI = 1) induced apoptosis in approximately 30% of cells, whereas increasing numbers of bacteria (MOI = 10 to 100) did not induce apoptosis. Apoptosis was observed in only 11% of cells with associated bacteria, whereas >84% of cells with no adherent bacteria were apoptotic. TNF-α was a key contributor to apoptosis, since (i) culture supernatants from cells infected with gonococci (MOI = 1) induced apoptosis in naïve cultures, suggesting that a soluble factor was responsible; (ii) gonococcal infection-induced apoptosis was inhibited with anti-TNF-α antibodies; and (iii) the addition of exogenous TNF-α induced apoptosis, which was inhibited by the presence of increasing numbers of bacteria (MOI = 10 to 100). These data suggest that TNF-α-mediated apoptosis of FT epithelial cells is likely a primary host defense mechanism to prevent pathogen colonization. However, epithelial cell-associated gonococci have evolved a mechanism to protect the cells from undergoing TNF-α-mediated apoptosis, and this modulation of the host innate response may contribute to establishment of infection. Understanding the antiapoptotic mechanisms used by Neisseria gonorrhoeae will inform the pathogenesis of salpingitis and could suggest new intervention strategies for prevention and treatment of the disease. PMID:16714596

Radiosensitization effect of recombinant adenoviral-mediated PUMA gene on pancreatic carcinoma cells

International Nuclear Information System (INIS)

Zhu Dongming; Zhang Kejun; Li Dechun; Zhu Xuefeng; Yang Yong

2009-01-01

Objective: To study the effect of PUMA gene mediated by recombinant adenovirus vector combined with radiation on the pancreatic carcinoma. Methods: The PANC-1 cells were infected with Ad- PUMA (MOI=10, 50 and 100, respectively) for 48 h. The expression of PUMA mRNA and protein was detected by RT-PCR and Western blot, respectively. PANC-1 cells were divided into 4 groups: control group, transfection group, irradiation group and combined treatment group. The cell growth inhibition rate and apoptotic rate of PANC-1 cells were assessed by MTT assay and flow cytometry. Human pancreatic carcinomas were transplanted subcutaneously in nude mice, which were randomized into 4 groups: control group, transfection group, irradiation group and combined treatment group. Tumor growth rate and apoptotic index at different time points were recorded in 35 days. Results: The expression of PUMA mRNA and protein was increased with the increase of MOI of Ad-PUMA, which was does-dependant (MOI=10, mRNA=0.46± 0.02, protein=0.75± 0.09; MOI=50, mRNA=1.12±0.09, protein=1.01±0.18; MOI=100, mRNA=1.50±0.08, protein= 1.80±0.15; P 3 , (39.5±9.23)mm 3 , (33.6±10.3)mm 3 and (52.0±11.43)mm 3 , respectively, P<0.05]. And the apoptotic index was increased in the same manner (AI=0.43±0.05, 0.29±0.10, 0.24±0.05 and 0.00±0.00, respectively, P<0.05). Conclusions: Recombinant adenoviral-mediated PUMA gene combined with irradiation could increase the cell-killing effect on pancreatic carcinoma. It is better than that of either one kind of therapy. (authors)

Characterization of viroplasm formation during the early stages of rotavirus infection

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Isa Pavel

2010-11-01

Full Text Available Abstract Background During rotavirus replication cycle, electron-dense cytoplasmic inclusions named viroplasms are formed, and two non-structural proteins, NSP2 and NSP5, have been shown to localize in these membrane-free structures. In these inclusions, replication of dsRNA and packaging of pre-virion particles occur. Despite the importance of viroplasms in the replication cycle of rotavirus, the information regarding their formation, and the possible sites of their nucleation during the early stages of infection is scarce. Here, we analyzed the formation of viroplasms after infection of MA104 cells with the rotavirus strain RRV, using different multiplicities of infection (MOI, and different times post-infection. The possibility that viroplasms formation is nucleated by the entering viral particles was investigated using fluorescently labeled purified rotavirus particles. Results The immunofluorescent detection of viroplasms, using antibodies specific to NSP2 showed that both the number and size of viroplasms increased during infection, and depend on the MOI used. Small-size viroplasms predominated independently of the MOI or time post-infection, although at MOI's of 2.5 and 10 the proportion of larger viroplasms increased. Purified RRV particles were successfully labeled with the Cy5 mono reactive dye, without decrease in virus infectivity, and the labeled viruses were clearly observed by confocal microscope. PAGE gel analysis showed that most viral proteins were labeled; including the intermediate capsid protein VP6. Only 2 out of 117 Cy5-labeled virus particles colocalized with newly formed viroplasms at 4 hours post-infection. Conclusions The results presented in this work suggest that during rotavirus infection the number and size of viroplasm increases in an MOI-dependent manner. The Cy5 in vitro labeled virus particles were not found to colocalize with newly formed viroplasms, suggesting that they are not involved in viroplasm

Intermediates in monensin biosynthesis: A late step in biosynthesis of the polyether ionophore monensin is crucial for the integrity of cation binding

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Wolfgang Hüttel

2014-02-01

Full Text Available Polyether antibiotics such as monensin are biosynthesised via a cascade of directed ring expansions operating on a putative polyepoxide precursor. The resulting structures containing fused cyclic ethers and a lipophilic backbone can form strong ionophoric complexes with certain metal cations. In this work, we demonstrate for monensin biosynthesis that, as well as ether formation, a late-stage hydroxylation step is crucial for the correct formation of the sodium monensin complex. We have investigated the last two steps in monensin biosynthesis, namely hydroxylation catalysed by the P450 monooxygenase MonD and O-methylation catalysed by the methyl-transferase MonE. The corresponding genes were deleted in-frame in a monensin-overproducing strain of Streptomyces cinnamonensis. The mutants produced the expected monensin derivatives in excellent yields (ΔmonD: 1.13 g L−1 dehydroxymonensin; ΔmonE: 0.50 g L−1 demethylmonensin; and double mutant ΔmonDΔmonE: 0.34 g L−1 dehydroxydemethylmonensin. Single crystals were obtained from purified fractions of dehydroxymonensin and demethylmonensin. X-ray structure analysis revealed that the conformation of sodium dimethylmonensin is very similar to that of sodium monensin. In contrast, the coordination of the sodium ion is significantly different in the sodium dehydroxymonensin complex. This shows that the final constitution of the sodium monensin complex requires this tailoring step as well as polyether formation.

Intermediates in monensin biosynthesis: A late step in biosynthesis of the polyether ionophore monensin is crucial for the integrity of cation binding.

Science.gov (United States)

Hüttel, Wolfgang; Spencer, Jonathan B; Leadlay, Peter F

2014-01-01

Polyether antibiotics such as monensin are biosynthesised via a cascade of directed ring expansions operating on a putative polyepoxide precursor. The resulting structures containing fused cyclic ethers and a lipophilic backbone can form strong ionophoric complexes with certain metal cations. In this work, we demonstrate for monensin biosynthesis that, as well as ether formation, a late-stage hydroxylation step is crucial for the correct formation of the sodium monensin complex. We have investigated the last two steps in monensin biosynthesis, namely hydroxylation catalysed by the P450 monooxygenase MonD and O-methylation catalysed by the methyl-transferase MonE. The corresponding genes were deleted in-frame in a monensin-overproducing strain of Streptomyces cinnamonensis. The mutants produced the expected monensin derivatives in excellent yields (ΔmonD: 1.13 g L(-1) dehydroxymonensin; ΔmonE: 0.50 g L(-1) demethylmonensin; and double mutant ΔmonDΔmonE: 0.34 g L(-1) dehydroxydemethylmonensin). Single crystals were obtained from purified fractions of dehydroxymonensin and demethylmonensin. X-ray structure analysis revealed that the conformation of sodium dimethylmonensin is very similar to that of sodium monensin. In contrast, the coordination of the sodium ion is significantly different in the sodium dehydroxymonensin complex. This shows that the final constitution of the sodium monensin complex requires this tailoring step as well as polyether formation.

Mutation Scanning in a Single and a Stacked Genetically Modified (GM) Event by Real-Time PCR and High Resolution Melting (HRM) Analysis

Science.gov (United States)

Ben Ali, Sina-Elisabeth; Madi, Zita Erika; Hochegger, Rupert; Quist, David; Prewein, Bernhard; Haslberger, Alexander G.; Brandes, Christian

2014-01-01

Genetic mutations must be avoided during the production and use of seeds. In the European Union (EU), Directive 2001/18/EC requires any DNA construct introduced via transformation to be stable. Establishing genetic stability is critical for the approval of genetically modified organisms (GMOs). In this study, genetic stability of two GMOs was examined using high resolution melting (HRM) analysis and real-time polymerase chain reaction (PCR) employing Scorpion primers for amplification. The genetic variability of the transgenic insert and that of the flanking regions in a single oilseed rape variety (GT73) and a stacked maize (MON88017 × MON810) was studied. The GT73 and the 5' region of MON810 showed no instabilities in the examined regions. However; two out of 100 analyzed samples carried a heterozygous point mutation in the 3' region of MON810 in the stacked variety. These results were verified by direct sequencing of the amplified PCR products as well as by sequencing of cloned PCR fragments. The occurrence of the mutation suggests that the 5' region is more suitable than the 3' region for the quantification of MON810. The identification of the single nucleotide polymorphism (SNP) in a stacked event is in contrast to the results of earlier studies of the same MON810 region in a single event where no DNA polymorphism was found. PMID:25365178

Familiarity speeds up visual short-term memory consolidation.

Science.gov (United States)

Xie, Weizhen; Zhang, Weiwei

2017-06-01

Existing long-term memory (LTM) can boost the number of retained representations over a short delay in visual short-term memory (VSTM). However, it is unclear whether and how prior LTM affects the initial process of transforming fragile sensory inputs into durable VSTM representations (i.e., VSTM consolidation). The consolidation speed hypothesis predicts faster consolidation for familiar relative to unfamiliar stimuli. Alternatively, the perceptual boost hypothesis predicts that the advantage in perceptual processing of familiar stimuli should add a constant boost for familiar stimuli during VSTM consolidation. To test these competing hypotheses, the present study examined how the large variance in participants' prior multimedia experience with Pokémon affected VSTM for Pokémon. In Experiment 1, the amount of time allowed for VSTM consolidation was manipulated by presenting consolidation masks at different intervals after the onset of to-be-remembered Pokémon characters. First-generation Pokémon characters that participants were more familiar with were consolidated faster into VSTM as compared with recent-generation Pokémon characters that participants were less familiar with. These effects were absent in participants who were unfamiliar with both generations of Pokémon. Although familiarity also increased the number of retained Pokémon characters when consolidation was uninterrupted but still incomplete due to insufficient encoding time in Experiment 1, this capacity effect was absent in Experiment 2 when consolidation was allowed to complete with sufficient encoding time. Together, these results support the consolidation speed hypothesis over the perceptual boost hypothesis and highlight the importance of assessing experimental effects on both processing and representation aspects of VSTM. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

AEGY-28 Cell Line of Aedes aegypti (Diptera Culicidae is Infection Refractory to Dengue 2 and Yellow Fever Virus

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Nadia Y. Castañeda

2007-07-01

Full Text Available Mosquito cell derived cultures are useful tools for arbovirus isolation, identification or characterization. For studying dengue (DENV and yellow fever viruses (YFV Aedes albopictus C6/36 or Aedes pseudoscutellaris AP-61 cell lines, are normally used. The Aedes aegypti AEGY-28 cell line was obtained from embryonic tissues and characterized previously by one of us. In order to evaluate its susceptibility to two Flavivirus, AEGY- 28 cells were inoculated with different multiplicity of infection (MOI with type 2 DENV (COL-789, MOI: 1 and 5 and YFV clinical isolates (V-341, MOI 0,02 then processed at different times post infection (p.i.. Immunostai ning and fluorometric cell-ELISA were carried out to identify and quantify viral antigens. C6/36 and Vero cells were used as positive controls. Unexpectedly, immunoreactivity was not found in inoculated AEGY-28 cells, even in higher MOI or late times p.i., therefore antigen quantification using fluorometric cell-ELISA were not  plausible. Reverse transcriptase PCR with specific primers did not detect viral RNA in AEGY-28 inoculated cells. We can conclude that Aedes aegypti AEGY-28 cell line is not susceptible to dengue and yellow fever Flavivirus, a finding possibly related with the lacking of specific molecules at the plasma membrane or absence of cell machinery necessary for viral replication.

Energetic benefits and adaptations in mammalian limbs: Scale effects and selective pressures.

Science.gov (United States)

Kilbourne, Brandon M; Hoffman, Louwrens C

2015-06-01

Differences in limb size and shape are fundamental to mammalian morphological diversity; however, their relevance to locomotor costs has long been subject to debate. In particular, it remains unknown if scale effects in whole limb morphology could partially underlie decreasing mass-specific locomotor costs with increasing limb length. Whole fore- and hindlimb inertial properties reflecting limb size and shape-moment of inertia (MOI), mass, mass distribution, and natural frequency-were regressed against limb length for 44 species of quadrupedal mammals. Limb mass, MOI, and center of mass position are negatively allometric, having a strong potential for lowering mass-specific locomotor costs in large terrestrial mammals. Negative allometry of limb MOI results in a 40% reduction in MOI relative to isometry's prediction for our largest sampled taxa. However, fitting regression residuals to adaptive diversification models reveals that codiversification of limb mass, limb length, and body mass likely results from selection for differing locomotor modes of running, climbing, digging, and swimming. The observed allometric scaling does not result from selection for energetically beneficial whole limb morphology with increasing size. Instead, our data suggest that it is a consequence of differing morphological adaptations and body size distributions among quadrupedal mammals, highlighting the role of differing limb functions in mammalian evolution. © 2015 The Author(s). Evolution © 2015 The Society for the Study of Evolution.

First detection of a human astrovirus type 8 in a child with diarrhea in Belém, Brazil: comparison with other strains worldwide and identification of possible three lineages

Directory of Open Access Journals (Sweden)

Yvone B Gabbay

2007-06-01

Full Text Available This study describes the genetic relationships of the first human astrovirus type-8 (HAstV-8 detected in Belém-Brazil, during a public hospital-based study. This strain was compared with other HAstV-8 strains identified elsewhere which have sequences available at GeneBank. The regions ORF1a (primers Mon348/Mon340 and ORF2 (primers Mon269/Mon270 were analyzed by nucleotide sequencing and a high similarity rate was observed among the Belém strain and other HAstV-8 strains. In ORF1a, homology values of 93-100% were detected, and in ORF2 96-99%. Considering the sequence variation (7% observed in ORF2 region, it was suggested that HAstV-8 strains could be divided in three different lineages.

Ancient Martian aeolian processes and palaeomorphology reconstructed from the Stimson formation on the lower slope of Aeolis Mons, Gale crater, Mars

Science.gov (United States)

Banham, Steve G.; Gupta, Sanjeev; Rubin, David M.; Watkins, Jessica A.; Sumner, Dawn Y.; Edgett, Kenneth S.; Grotzinger, John P.; Lewis, Kevin W.; Edgar, Lauren; Stack, Kathryn M.; Barnes, Robert; Bell, Jame F. III; Day, Mackenzie D.; Ewing, Ryan C.; Lapotre, Mathieu G.A.; Stein, Nathan T.; Rivera-Hernandez, Frances; Vasavada, Ashwin R.

2018-01-01

Reconstruction of the palaeoenvironmental context of Martian sedimentary rocks is central to studies of ancient Martian habitability and regional palaeoclimate history. This paper reports the analysis of a distinct aeolian deposit preserved in Gale crater, Mars, and evaluates its palaeomorphology, the processes responsible for its deposition, and its implications for Gale crater geological history and regional palaeoclimate. Whilst exploring the sedimentary succession cropping out on the northern flank of Aeolis Mons, Gale crater, the Mars Science Laboratory rover Curiosity encountered a decametre‐thick sandstone succession, named the Stimson formation, unconformably overlying lacustrine deposits of the Murray formation. The sandstone contains sand grains characterized by high roundness and sphericity, and cross‐bedding on the order of 1 m in thickness, separated by sub‐horizontal bounding surfaces traceable for tens of metres across outcrops. The cross‐beds are composed of uniform thickness cross‐laminations interpreted as wind‐ripple strata. Cross‐sets are separated by sub‐horizontal bounding surfaces traceable for tens of metres across outcrops that are interpreted as dune migration surfaces. Grain characteristics and presence of wind‐ripple strata indicate deposition of the Stimson formation by aeolian processes. The absence of features characteristic of damp or wet aeolian sediment accumulation indicate deposition in a dry aeolian system. Reconstruction of the palaeogeomorphology suggests that the Stimson dune field was composed largely of simple sinuous crescentic dunes with a height of ca10 m, and wavelengths of ca 150 m, with local development of complex dunes. Analysis of cross‐strata dip‐azimuths indicates that the general dune migration direction and hence net sediment transport was towards the north‐east. The juxtaposition of a dry aeolian system unconformably above the lacustrine Murray formation represents starkly

Indium determination by spectral overlappings of lines in atomic absorption spectrometry

International Nuclear Information System (INIS)

Gomez, J.J.; Huicque, L. d'; Garcia Vior, L.O.

1991-01-01

A molybdenum hollow-cathode lamp filled with neon can be used to determine indium. Characteristic concentration for this element is 4.5 mg/L in the 325 nm spectral region for the Mo(I) 325.621 nm line. In addition, values of 0.4 mg/L and 0.3 mg/L are obtained with the Mo(I) 410.215 nm and Ne(I) 451.151 nm lines, respectively. These spectral overlappings allow the determination of indium in silver-cadmium-indium alloys. (Author) [es

Les corps étrangers trachéobronchiques a propos de 107 cas ...

African Journals Online (AJOL)

Résultats : nous avons retrouvé en moyenne 9 cas de Ce par an. L'âge moyen de nos patients était de 30 mois avec des extrêmes allant de 6 mois à 15 ans. Parmi ces enfants, 70% avaient un âge compris entre 1 et 3 ans. Le syndrome de pénétration a été retrouvé dans 77,6% des cas. Le symptôme le plus fréquent était ...

Strengthening the Security of ESA Ground Data Systems

Science.gov (United States)

Flentge, Felix; Eggleston, James; Garcia Mateos, Marc

2013-08-01

A common approach to address information security has been implemented in ESA's Mission Operations (MOI) Infrastructure during the last years. This paper reports on the specific challenges to the Data Systems domain within the MOI and how security can be properly managed with an Information Security Management System (ISMS) according to ISO 27001. Results of an initial security risk assessment are reported and the different types of security controls that are being implemented in order to reduce the risks are briefly described.

Pop / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2004-01-01

Heliplaatidest: Timbaland & Magoo "Under Construction Part II", Courtney, Love "America's Sweetheart", Lambchop "Aw C'mon / No You C'mon", Louie Vega "Elements of Life", Un Caddie Renverse Dans L'Herbre "Like a packed cupboard but quite..."

Differential effects of multiplicity of infection on Helicobacter pylori-induced signaling pathways and interleukin-8 gene transcription.

Science.gov (United States)

Ritter, Birgit; Kilian, Petra; Reboll, Marc Rene; Resch, Klaus; DiStefano, Johanna Kay; Frank, Ronald; Beil, Winfried; Nourbakhsh, Mahtab

2011-02-01

Interleukin-8 (IL-8) plays a central role in the pathogenesis of Helicobacter pylori infection. We used four different H. pylori strains isolated from patients with gastritis or duodenal ulcer disease to examine their differential effects on signaling pathways and IL-8 gene response in gastric epithelial cells. IL-8 mRNA level is elevated in response to high (100) multiplicity of infection (MOI) independent of cagA, vacA, and dupA gene characteristics. By lower MOIs (1 or 10), only cagA ( + ) strains significantly induce IL-8 gene expression. This is based on differential regulation of IL-8 promoter activity. Analysis of intracellular signaling pathways indicates that H. pylori clinical isolates induce IL-8 gene transcription through NF-κB p65, but by a MOI-dependent differential activation of MAPK pathways. Thus, the major virulence factors of H. pylori CagA, VacA, and DupA might play a minor role in the level of IL-8 gene response to a high bacterial load.

Attenuation of virus production at high multiplicities of infection in Aureococcus anophagefferens

Energy Technology Data Exchange (ETDEWEB)

Brown, Christopher M.; Bidle, Kay D., E-mail: bidle@marine.rutgers.edu

2014-10-15

Infection dynamics (saturation kinetics, infection efficiency, adsorption and burst size) for the Aureococcus anophagefferens-Brown Tide virus (AaV) system were investigated using susceptible and resistant strains. Adsorption assays revealed that virus affinity to the cell surface is a key determinant of infectivity. Saturation of infection occurred at a multiplicity of infection (MOI) of 8 viruses per host and resulted in ∼90–95% of infected cells, with burst sizes ranging from 164 to 191. Insight from the AaV genome implicates recycling of host nucleotides rather than de novo synthesis as a constraint on viral replication. Viral yields and mean burst sizes were significantly diminished with increasing MOI. This phenomenon, which was reminiscent of phage-induced ‘lysis from without’, appeared to be caused by viral contact and was unrelated to bacteria, signaling/toxic compounds, or defective interfering viruses. We posit that high-MOI effects attenuate viral proliferation in natural systems providing a negative feedback on virus-induced bloom collapse.

Predicting octane number using nuclear magnetic resonance spectroscopy and artificial neural networks

KAUST Repository

Abdul Jameel, Abdul Gani; Oudenhoven, Vincent Van; Emwas, Abdul-Hamid M.; Sarathy, Mani

2018-01-01

Machine learning algorithms are attracting significant interest for predicting complex chemical phenomenon. In this work, a model to predict research octane number (RON) and motor octane number (MON) of pure hydrocarbons, hydrocarbon-ethanol blends and gasoline-ethanol blends has been developed using artificial neural networks (ANN) and molecular parameters from 1H nuclear Magnetic Resonance (NMR) spectroscopy. RON and MON of 128 pure hydrocarbons, 123 hydrocarbon-ethanol blends of known composition and 30 FACE (fuels for advanced combustion engines) gasoline-ethanol blends were utilized as a dataset to develop the ANN model. The effect of weight % of seven functional groups including paraffinic CH3 groups, paraffinic CH2 groups, paraffinic CH groups, olefinic -CH=CH2 groups, naphthenic CH-CH2 groups, aromatic C-CH groups and ethanolic OH groups on RON and MON was studied. The effect of branching (i.e., methyl substitution), denoted by a parameter termed as branching index (BI), and molecular weight (MW) were included as inputs along with the seven functional groups to predict RON and MON. The topology of the developed ANN models for RON (9-540-314-1) and MON (9-340-603-1) have two hidden layers and a large number of nodes, and was validated against experimentally measured RON and MON of pure hydrocarbons, hydrocarbon-ethanol and gasoline-ethanol blends; a good correlation (R2=0.99) between the predicted and the experimental data was obtained. The average error of prediction for both RON and MON was found to be 1.2 which is close to the range of experimental uncertainty. This shows that the functional groups in a molecule or fuel can be used to predict its ON, and the complex relationship between them can be captured by tools like ANN.

Discrete Element Simulations of Density-Driven Volcanic Deformation: Applications to Martian and Terrestrial Volcanoes

Science.gov (United States)

Farrell, L. L.; McGovern, P. J.; Morgan, J. K.

2008-12-01

We have carried out 2-D numerical simulations using the discrete element method (DEM) to investigate density-driven deformation in volcanic edifices on Earth (e.g., Hawaii) and Mars (e.g., Olympus Mons and Arsia Mons). Located within volcanoes are series of magma chambers, reservoirs, and conduits where magma travels and collects. As magma differentiates, dense minerals settle out, building thick accumulations referred to as cumulates that can flow ductilely due to stresses imparted by gravity. To simulate this process, we construct granular piles subject to Coulomb frictional rheology, incrementally capture internal rectangular regions to which higher densities and lower interparticle friction values are assigned (analogs for denser, weaker cumulates), and then bond the granular edifice. Thus, following each growth increment, the edifice is allowed to relax gravitationally with a reconfigured weak cumulate core. The presence and outward spreading of the cumulate causes the development of distinctive structural and stratigraphic patterns. We obtained a range of volcanic shapes that vary from broad, shallowly dipping flanks reminiscent of those of Olympus Mons, to short, steep surface slopes more similar to Arsia Mons. Edifices lacking internal cumulate exhibit relatively horizontal strata compared to the high-angle, inward dipping strata that develops within the cumulate-bearing edifices. Our simulated volcanoes also illustrate a variety of gravity driven deformation features, including regions of thrust faulting within the flanks and large-scale flank collapses, as observed in Hawaii and inferred on Olympus Mons. We also see significant summit subsidence, and of particular interest, distinct summit calderas. The broad, flat caldera and convex upward profile of Arsia Mons appears to be well-simulated by cumulate-driven volcanic spreading. In contrast, the concave upward slopes of Olympus Mons are more challenging to reproduce, and instead are attributed to volcanic

Predicting octane number using nuclear magnetic resonance spectroscopy and artificial neural networks

KAUST Repository

Abdul Jameel, Abdul Gani

2018-04-17

Machine learning algorithms are attracting significant interest for predicting complex chemical phenomenon. In this work, a model to predict research octane number (RON) and motor octane number (MON) of pure hydrocarbons, hydrocarbon-ethanol blends and gasoline-ethanol blends has been developed using artificial neural networks (ANN) and molecular parameters from 1H nuclear Magnetic Resonance (NMR) spectroscopy. RON and MON of 128 pure hydrocarbons, 123 hydrocarbon-ethanol blends of known composition and 30 FACE (fuels for advanced combustion engines) gasoline-ethanol blends were utilized as a dataset to develop the ANN model. The effect of weight % of seven functional groups including paraffinic CH3 groups, paraffinic CH2 groups, paraffinic CH groups, olefinic -CH=CH2 groups, naphthenic CH-CH2 groups, aromatic C-CH groups and ethanolic OH groups on RON and MON was studied. The effect of branching (i.e., methyl substitution), denoted by a parameter termed as branching index (BI), and molecular weight (MW) were included as inputs along with the seven functional groups to predict RON and MON. The topology of the developed ANN models for RON (9-540-314-1) and MON (9-340-603-1) have two hidden layers and a large number of nodes, and was validated against experimentally measured RON and MON of pure hydrocarbons, hydrocarbon-ethanol and gasoline-ethanol blends; a good correlation (R2=0.99) between the predicted and the experimental data was obtained. The average error of prediction for both RON and MON was found to be 1.2 which is close to the range of experimental uncertainty. This shows that the functional groups in a molecule or fuel can be used to predict its ON, and the complex relationship between them can be captured by tools like ANN.

The effect of nitrate and monensin on in vitro ruminal fermentation.

Science.gov (United States)

Capelari, M; Powers, W

2017-11-01

Two experiments evaluated the effect of calcium ammonium nitrate decahydrate (calcium nitrate [NIT]) and monensin sodium (MON) on in vitro fermentation parameters of 2 contrasting diets (100:0 and 10:90 forage-to-concentrate ratios). Diet addition of NIT (0, 1.25, and 2.5 g/100 g DM) and MON (0, 3, and 6 mg/L) were tested alone and combined (9 treatments total; 5 bottles per treatment). Mixed ruminal microorganisms were incubated in anaerobic media containing 0.5 g of substrate diet, 1 of 9 treatments, and 40 mL buffer solution. Incubations were performed in batch cultures for 48 h at 39°C. Headspace gas volume was measured and sampled at 4, 8, 12, 24, and 48 h, and the VFA profile was assessed at the end of the experiment. Total gas production was reduced by NIT (87.9 vs. 94.6 mL; 0.10), but molar proportions of acetate and butyrate were reduced by MON ( molar proportion was increased in both experiments by MON ( < 0.01) and further increased in Exp. 2 when the additives were combined at lower doses ( < 0.01). Compared to the control treatment, the acetate:propionate (A:P) ratio was reduced by MON in Exp. 1(1.2 vs. 2.8; < 0.01) and Exp. 2 (1.0 vs. 2.3; < 0.01). Fermentation efficiency (%) was increased by MON (81.7 vs. 73.7%; < 0.01) and further increased in Exp. 2 when the additives were combined at lower doses (87.2 vs. 76.6%; < 0.01). The combination of NIT and MON in 2 contrasting diets proved beneficial by altering fermentation products toward lower CH and more propionate; however, the addition of NIT consistently increased NO production. Negative effects of the additives on IVDMD were found only when the additives were combined at higher doses.

NEAR-INFRARED CIRCULAR AND LINEAR POLARIMETRY OF MONOCEROS R2

Energy Technology Data Exchange (ETDEWEB)

Kwon, Jungmi; Tamura, Motohide [Department of Astronomy, Graduate School of Science, The University of Tokyo, 113-0033 (Japan); Hough, James H. [University of Hertfordshire, Hatfield, Herts AL10 9AB (United Kingdom); Nagata, Tetsuya [Kyoto University, Sakyo-ku, Kyoto 606-8502 (Japan); Kusakabe, Nobuhiko [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan)

2016-09-01

We have conducted simultaneous JHK{sub s}-band imaging circular and linear polarimetry of the Monoceros R2 (Mon R2) cluster. We present results from deep and wide near-infrared linear polarimetry of the Mon R2 region. Prominent and extended polarized nebulosities over the Mon R2 field are revisited, and an infrared reflection nebula associated with the Mon R2 cluster and two local reflection nebulae, vdB 67 and vdB 69, is detected. We also present results from deep imaging circular polarimetry in the same region. For the first time, the observations show relatively high degrees of circular polarization (CP) in Mon R2, with as much as approximately 10% in the K{sub s} band. The maximum CP extent of a ring-like nebula around the Mon R2 cluster is approximately 0.60 pc, while that of a western nebula, around vdB 67, is approximately 0.24 pc. The extended size of the CP is larger than those seen in the Orion region around IRc2, while the maximum degree of CP of ∼10% is smaller than those of ∼17% seen in the Orion region. Nonetheless, both the CP size and degree of this region are among the largest in our infrared CP survey of star-forming regions. We have also investigated the time variability of the degree of the polarization of several infrared sources and found possible variations in three sources.

Clinical and radiographical evaluation of mineral trioxide aggregate, biodentine and propolis as pulpotomy medicaments in primary teeth

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Bharti Kusum

2015-11-01

Full Text Available Objectives The purpose of this study was to evaluate the efficacy of mineral trioxide aggregate (MTA, Biodentine and Propolis as pulpotomy medicaments in primary dentition, both clinically and radiographically. Materials and Methods A total of 75 healthy 3 to 10 yr old children each having at least one carious primary molar tooth were selected. Random assignment of the pulpotomy medicaments was done as follows: Group I, MTA; Group II, Biodentine; Group III, Propolis. All the pulpotomized teeth were evaluated at 3, 6, and 9 mon clinically and radiographically, based on the scoring criteria system. Results The clinical success rates were found to be similar among the three groups at 3 and 6 mon where as a significant decrease in success rate was observed in Group III (84% compared to both Group I (100% and Group II (100% at 9 mon. Radiographic success rates over a period of 9 mon in Groups I, II, and III were 92, 80, and 72%, respectively. Conclusions Teeth treated with MTA and Biodentine showed more favorable clinical and radiographic success as compared to Propolis at 9 mon follow-up.

Tharsis Limb Cloud

Science.gov (United States)

2005-01-01

[figure removed for brevity, see original site] Annotated image of Tharsis Limb Cloud 7 September 2005 This composite of red and blue Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired on 6 July 2005 shows an isolated water ice cloud extending more than 30 kilometers (more than 18 miles) above the martian surface. Clouds such as this are common in late spring over the terrain located southwest of the Arsia Mons volcano. Arsia Mons is the dark, oval feature near the limb, just to the left of the 'T' in the 'Tharsis Montes' label. The dark, nearly circular feature above the 'S' in 'Tharsis' is the volcano, Pavonis Mons, and the other dark circular feature, above and to the right of 's' in 'Montes,' is Ascraeus Mons. Illumination is from the left/lower left. Season: Northern Autumn/Southern Spring

Perfil audiométrico e de emissões otoacústicas evocadas por produto de distorção em gestores de trânsito expostos a monóxido de carbono e ruído Audiometric profile and evoked otoacoustic emissions per product of distortion in transit managers, exposed to carbon monoxide and noise

Directory of Open Access Journals (Sweden)

Soraya de Carvalho Rocha

2013-01-01

Full Text Available OBJETIVO: avaliar o perfil audiométrico e de emissões otoacústicas evocadas por produto de distorção em gestores de trânsito, expostos a monóxido de carbono e ruído, bem como constatar a presença de ambos agentes nos postos de trabalho. MÉTODO:estudo transversal, descritivo, com 37 gestores do trânsito, submetidos a anamnese, meatoscopia, audiometria tonal e emissões otoacústicas, distribuídos em: G1, composto por 18 indivíduos sem histórico de exposição concomitante a monóxido de carbono e ruído; e, G2, formado por 19 trabalhadores expostos simultaneamente aos dois agentes. Para pesquisa da presença dos agentes no ambiente foram utilizadas audiodosímetrias e avaliações de curta duração com medidor instantâneo. As variáveis de anamnese foram analisadas segundo o teste t Student e Mann-Whitney. Para as medidas de otoemissões acústicas e de limiares tonais utilizou-se testes de qui-quadrado (χ2 ou exato de Fisher e dos postos sinalizados de Wilcoxon com significância de 5%. RESULTADOS: foi constatada presença de monóxido de carbono e ruído durante a atividade dos trabalhadores. Não foi observada diferença significante na idade e tempo de função. O G2 obteve média de limiares tonais maior que G1, para orelha direita, em 1KHz (p=0,050 e para orelha esquerda em 3KHz (p=0,016 e 4KHz (p=0,028; e, comparados os limiares tonais alterados G2 apresentou diferença maior em 3KHz na orelha esquerda (p=0,003. Nas emissões otoacústicas, G2 apresentou maior ausência de respostas que G1 em 2.730Hz e 3.218Hz (p=0.016 para orelha direita. CONCLUSÃO: trabalhadores expostos a monóxido de carbono e ruído apresentaram piores resultados audiométricos e nas emissões otoacústicas quando comparado ao grupo de não expostos.PURPOSE: to evaluate the hearing profile and otoacoustic emission evoked by distortion product in Traffic Managers exposed to noise and carbon monoxide, as well as to establish the presence of both agents

Perfil audiométrico e de emissões otoacústicas evocadas por produto de distorção em gestores de trânsito expostos a monóxido de carbono e ruído Audiometric profile and evoked otoacoustic emissions per product of distortion in transit managers, exposed to carbon monoxide and noise

Directory of Open Access Journals (Sweden)

Soraya de Carvalho Rocha

2013-04-01

Full Text Available OBJETIVO: avaliar o perfil audiométrico e de emissões otoacústicas evocadas por produto de distorção em gestores de trânsito, expostos a monóxido de carbono e ruído, bem como constatar a presença de ambos agentes nos postos de trabalho. MÉTODO:estudo transversal, descritivo, com 37 gestores do trânsito, submetidos a anamnese, meatoscopia, audiometria tonal e emissões otoacústicas, distribuídos em: G1, composto por 18 indivíduos sem histórico de exposição concomitante a monóxido de carbono e ruído; e, G2, formado por 19 trabalhadores expostos simultaneamente aos dois agentes. Para pesquisa da presença dos agentes no ambiente foram utilizadas audiodosímetrias e avaliações de curta duração com medidor instantâneo. As variáveis de anamnese foram analisadas segundo o teste t Student e Mann-Whitney. Para as medidas de otoemissões acústicas e de limiares tonais utilizou-se testes de qui-quadrado (χ2 ou exato de Fisher e dos postos sinalizados de Wilcoxon com significância de 5%. RESULTADOS: foi constatada presença de monóxido de carbono e ruído durante a atividade dos trabalhadores. Não foi observada diferença significante na idade e tempo de função. O G2 obteve média de limiares tonais maior que G1, para orelha direita, em 1KHz (p=0,050 e para orelha esquerda em 3KHz (p=0,016 e 4KHz (p=0,028; e, comparados os limiares tonais alterados G2 apresentou diferença maior em 3KHz na orelha esquerda (p=0,003. Nas emissões otoacústicas, G2 apresentou maior ausência de respostas que G1 em 2.730Hz e 3.218Hz (p=0.016 para orelha direita. CONCLUSÃO: trabalhadores expostos a monóxido de carbono e ruído apresentaram piores resultados audiométricos e nas emissões otoacústicas quando comparado ao grupo de não expostos.PURPOSE: to evaluate the hearing profile and otoacoustic emission evoked by distortion product in Traffic Managers exposed to noise and carbon monoxide, as well as to establish the presence of both agents

Economies of scale and competitiveness of an enterprise

OpenAIRE

Maksvytienė, Inga

2007-01-01

Straipsnyje vertinama masto ekonomijos bei neekonomijos ir įmonės dydžio tarpusavio ryšio poveikio įmonės konkurencingumui galimybė. Veikiant masto ekonomijos ir neekonomijos sąveikos mechanizmui, vidutiniai gamybos kaštai mažėja ir įmonės konkurencingumas didėja. The aim of the research is to introduce the role of enterprise scale under the conditions of competition. In the article the theoretical model of scale economies and diseconomies interaction influence on the competitive ability o...

Radiation Levels around the LHC

CERN Document Server

Mala, P; Calviani, M; Nordt, A

2013-01-01

This work discuss on the radiation levels measured around the LHC machine during the 2012 operational year. The doses and particle fluences are measured primarily by RadMon detectors – about 300 RadMons are installed around the accelerator – and by thermoluminescent detectors. In addition, BLMs, IG5/PMI ionisation chambers as well as FGCs can be used for corresponding cumulated dose evaluations. The probability of SEE depends directly on the high-energy hadron (HEH) fluence, so this is the main parameter that is calculated based on RadMons counts.

Biodegradable Oxamide-Phenylene-Based Mesoporous Organosilica Nanoparticles with Unprecedented Drug Payloads for Delivery in Cells

KAUST Repository

Croissant, Jonas

2016-06-03

We describe biodegradable mesoporous hybrid NPs in the presence of proteins, and its application for drug delivery. We synthesized oxamide-phenylene-based mesoporous organosilica nanoparticles (MON) in the absence of silica source which had a remarkably high organic content with a high surface area. Oxamide functions provided biodegradability in the presence of trypsin model proteins. MON displayed exceptionally high payloads of hydrophilic and hydrophobic drugs (up to 84 wt%), and a unique zero premature leakage without the pore capping, unlike mesoporous silica. MON were biocompatible and internalized into cancer cells for drug delivery.

Marketing strategies oh the companies delivering internet services

OpenAIRE

Egidė-Patašienė, Ilona

2009-01-01

Pirmoje darbo dalyje buvo įvertinta ir nagrinėta įmonės strateginė orientacija, strateginio planavimo ir valdymo esmė, apibrėžta marketingo strategijos samprata, pateikti pagrindiniai marketingo strategijų tipai, priklausomai nuo įmonės užimamos pozicijos rinkoje, konkurentų ir kt. veiksnių bei nusakytas teorinis marketingo strategijos įmonėje sukūrimo modelis. Antroje darbo dalyje, remiantis moksliniais straipsniais bei rastais pavyzdžiais mokslinėje marketingo literatūroje, buvo įvertinti m...

Strategy theories implication in lithuanian aerospace enterprises

OpenAIRE

Rudminaitis, Vytautas

2006-01-01

Dėl nuolat augančios konkurencijos ir aplinkos dinamiškumo strateginio planavimo svarba pastaruoju metu labai išaugo. Strategija – tai priemonė, padedanti pasiruošti pokyčiams ir numatyti artimesnius bei tolimesnius žingsnius. Todėl strategijos formavimo procesas turi būti neatsiejama kiekvienos įmonės valdymo dalis, kadangi sėkmingas strateginio planavimo pritaikymas ne maža dalimi nulemia įmonės sėkmingą veiklą Tyrimo objektas yra strategijos formavimo procesas Lietuvos aeronautikos įmonėse...

Comparative population structure of Plasmodium malariae and Plasmodium falciparum under different transmission settings in Malawi

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Molyneux Malcolm E

2011-02-01

Full Text Available Abstract Background Described here is the first population genetic study of Plasmodium malariae, the causative agent of quartan malaria. Although not as deadly as Plasmodium falciparum, P. malariae is more common than previously thought, and is frequently in sympatry and co-infection with P. falciparum, making its study increasingly important. This study compares the population parameters of the two species in two districts of Malawi with different malaria transmission patterns - one seasonal, one perennial - to explore the effects of transmission on population structures. Methods Six species-specific microsatellite markers were used to analyse 257 P. malariae samples and 257 P. falciparum samples matched for age, gender and village of residence. Allele sizes were scored to within 2 bp for each locus and haplotypes were constructed from dominant alleles in multiple infections. Analysis of multiplicity of infection (MOI, population differentiation, clustering of haplotypes and linkage disequilibrium was performed for both species. Regression analyses were used to determine association of MOI measurements with clinical malaria parameters. Results Multiple-genotype infections within each species were common in both districts, accounting for 86.0% of P. falciparum and 73.2% of P. malariae infections and did not differ significantly with transmission setting. Mean MOI of P. falciparum was increased under perennial transmission compared with seasonal (3.14 vs 2.59, p = 0.008 and was greater in children compared with adults. In contrast, P. malariae mean MOI was similar between transmission settings (2.12 vs 2.11 and there was no difference between children and adults. Population differentiation showed no significant differences between villages or districts for either species. There was no evidence of geographical clustering of haplotypes. Linkage disequilibrium amongst loci was found only for P. falciparum samples from the seasonal transmission

Recombinant adeno-associated virus mediates a high level of gene transfer but less efficient integration in the K562 human hematopoietic cell line.

Science.gov (United States)

Malik, P; McQuiston, S A; Yu, X J; Pepper, K A; Krall, W J; Podsakoff, G M; Kurtzman, G J; Kohn, D B

1997-03-01

We tested the ability of a recombinant adeno-associated virus (rAAV) vector to express and integrate exogenous DNA into human hematopoietic cells in the absence of selection. We developed an rAAV vector, AAV-tNGFR, carrying a truncated rat nerve growth factor receptor (tNGFR) cDNA as a cell surface reporter under the control of the Moloney murine leukemia virus (MoMuLV) long terminal repeat. An analogous MoMuLV-based retroviral vector (L-tNGFR) was used in parallel, and gene transfer and expression in human hematopoietic cells were assessed by flow cytometry and DNA analyses. Following gene transfer into K562 cells with AAV-tNGFR at a multiplicity of infection (MOI) of 13 infectious units (IU), 26 to 38% of cells expressed tNGFR on the surface early after transduction, but the proportion of tNGFR expressing cells steadily declined to 3.0 to 3.5% over 1 month of culture. At an MOI of 130 IU, nearly all cells expressed tNGFR immediately posttransduction, but the proportion of cells expressing tNGFR declined to 62% over 2 months of culture. The decline in the proportion of AAV-tNGFR-expressing cells was associated with ongoing losses of vector genomes. In contrast, K562 cells transduced with the retroviral vector L-tNGFR expressed tNGFR in a constant fraction. Integration analyses on clones showed that integration occurred at different sites. Integration frequencies were estimated at about 49% at an MOI of 130 and 2% at an MOI of 1.3. Transduction of primary human CD34+ progenitor cells by AAV-tNGFR was less efficient than with K562 cells and showed a declining percentage of cells expressing tNGFR over 2 weeks of culture. Thus, purified rAAV caused very high gene transfer and expression in human hematopoietic cells early after transduction, which steadily declined during cell passage in the absence of selection. Although the efficiency of integration was low, overall integration was markedly improved at a high MOI. While prolonged episomal persistence may be adequate

Isolation, Characterization, and Application of Bacteriophage LPSE1 Against Salmonella enterica in Ready to Eat (RTE Foods

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Chenxi Huang

2018-05-01

Full Text Available Salmonella infection is an important foodborne consumer health concern that can be mitigated during food processing. Bacteriophage therapy imparts many advantages over conventional chemical preservatives including pathogen specificity, natural derivation, potency, and providing a high degree of safety. The objective of this study aimed to isolate and characterize a phage that effectively control Salmonella food contamination. Out of 35 isolated phages, LPSE1 demonstrated a broad Salmonella host range, robust lytic ability, extensive pH tolerance, and prolonged thermal stability. The capacity for phage LPSE1 to control Salmonella Enteritidis-ATCC13076 in milk, sausage, and lettuce was established. Incubation of LPSE1 at 28°C in milk reduced recoverable Salmonella by approximately 1.44 log10 CFU/mL and 2.37 log10 CFU/mL at MOI of 1 and 100, respectively, as relative to the phage-excluded control. Upon administration of LPSE1 at an MOI of 1 in sausage, Salmonella count decreased 0.52 log10 at 28°C. At MOI of 100, the count decreased 0.49 log10 at 4°C. Incubation of LPSE1 on lettuce reduced recoverable Salmonella by 2.02 log10, 1.71 log10, and 1.45 log10 CFU/mL at an MOI of 1, 10, and 100, respectively, as relative to the negative control. Taken together, these findings establish LPSE1 as an effective weapon against human pathogenic Salmonella in various ready to eat foods.

Patterns of deformation and volcanic flows associated with lithospheric loading by large volcanoes on Venus

Science.gov (United States)

Mcgovern, Patrick J.; Solomon, Sean C.

1993-01-01

Magellan radar imaging and topography data are now available for a number of volcanoes on Venus greater than 100 km in radius. These data can be examined to reveal evidence of the flexural response of the lithosphere to the volcanic load. On Venus, erosion and sediment deposition are negligible, so tectonic evidence of deformation around large volcanoes should be evident except where buried by very young flows. Radar images reveal that most tectonic features and flow units on the flanks of these volcanoes have predominantly radial orientations. However, both Tepev Mons in Bell Regio and Sapas Mons in Atla Regio exhibit circumferential graben on their flanks. In addition, images reveal several flow units with an annular character around the north and west flanks of Tepev Mons. This pattern most likely results from ponding of flows in an annular flexural moat. Maat Mons in Atla Regio and Sif Mons in Eistla Regio are examples of volcanoes that lack circumferential graben and annular flows; discernible flow units and fractures on these constructs appear to be predominantly radial. Altimetry data can also provide evidence of flexural response. Tepev Mons is partially encircled by depressions that may be sections of a flexural moat that has not been completely filled. The locations of these depressions generally coincide with the annular flows described above. There is weaker evidence for such depressions around Maat Mons as well. The lack of circumferential tectonic features around most volcanoes on Venus might be explained by gradual moat filling and coverage by radial flows. The depressions around Tepev (and possible Maat) may indicate that this process is currently continuing. We use analytic models of plate flexure in an axisymmetric geometry to constrain the elastic plate thickness supporting Tepev Mons. If we consider the outer radius of the ponded flows to be the edge of a moat, we find that models with elastic plate thickness of 10-20 km fit best. Finite element

HIV-1 replication in cell lines harboring INI1/hSNF5 mutations

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Wu Xuhong

2006-08-01

Full Text Available Abstract Background INI1/hSNF5 is a cellular protein that directly interacts with HIV-1 integrase (IN. It is specifically incorporated into HIV-1 virions. A dominant negative mutant derived from INI1 inhibits HIV-1 replication. Recent studies indicate that INI1 is associated with pre-integration and reverse transcription complexes that are formed upon viral entry into the target cells. INI1 also is a tumor suppressor, biallelically deleted/mutated in malignant rhabdoid tumors. We have utilized cell lines derived from the rhabdoid tumors, MON and STA-WT1, that harbor either null or truncating mutations of INI1 respectively, to assess the effect of INI1 on HIV-1 replication. Results We found that while HIV-1 virions produced in 293T cells efficiently transduced MON and STA-WT1 cells, HIV-1 particle production was severely reduced in both of these cells. Reintroduction of INI1 into MON and STA-WT1 significantly enhanced the particle production in both cell lines. HIV-1 particles produced in MON cells were reduced for infectivity, while those produced in STA-WT1 were not. Further analysis indicated the presence of INI1 in those virions produced from STA-WT1 but not from those produced from MON cells. HIV-1 produced in MON cells were defective for synthesis of early and late reverse transcription products in the target cells. Furthermore, virions produced in MON cells were defective for exogenous reverse transcriptase activity carried out using exogenous template, primer and substrate. Conclusion Our results suggest that INI1-deficient cells exhibit reduced particle production that can be partly enhanced by re-introduction of INI1. Infectivity of HIV-1 produced in some but not all INI1 defective cells, is affected and this defect may correlate to the lack of INI1 and/or some other proteins in these virions. The block in early events of virion produced from MON cells appears to be at the stage of reverse transcription. These studies suggest that

HIV-1 replication in cell lines harboring INI1/hSNF5 mutations.

Science.gov (United States)

Sorin, Masha; Yung, Eric; Wu, Xuhong; Kalpana, Ganjam V

2006-08-31

INI1/hSNF5 is a cellular protein that directly interacts with HIV-1 integrase (IN). It is specifically incorporated into HIV-1 virions. A dominant negative mutant derived from INI1 inhibits HIV-1 replication. Recent studies indicate that INI1 is associated with pre-integration and reverse transcription complexes that are formed upon viral entry into the target cells. INI1 also is a tumor suppressor, biallelically deleted/mutated in malignant rhabdoid tumors. We have utilized cell lines derived from the rhabdoid tumors, MON and STA-WT1, that harbor either null or truncating mutations of INI1 respectively, to assess the effect of INI1 on HIV-1 replication. We found that while HIV-1 virions produced in 293T cells efficiently transduced MON and STA-WT1 cells, HIV-1 particle production was severely reduced in both of these cells. Reintroduction of INI1 into MON and STA-WT1 significantly enhanced the particle production in both cell lines. HIV-1 particles produced in MON cells were reduced for infectivity, while those produced in STA-WT1 were not. Further analysis indicated the presence of INI1 in those virions produced from STA-WT1 but not from those produced from MON cells. HIV-1 produced in MON cells were defective for synthesis of early and late reverse transcription products in the target cells. Furthermore, virions produced in MON cells were defective for exogenous reverse transcriptase activity carried out using exogenous template, primer and substrate. Our results suggest that INI1-deficient cells exhibit reduced particle production that can be partly enhanced by re-introduction of INI1. Infectivity of HIV-1 produced in some but not all INI1 defective cells, is affected and this defect may correlate to the lack of INI1 and/or some other proteins in these virions. The block in early events of virion produced from MON cells appears to be at the stage of reverse transcription. These studies suggest that presence of INI1 or some other host factor in virions and

Prenatal Phthalate, Perfluoroalkyl Acid, and Organochlorine Exposures and Term Birth Weight in Three Birth Cohorts

DEFF Research Database (Denmark)

Lenters, Virissa; Portengen, Lützen; Rignell-Hydbom, Anna

2016-01-01

body mass index. To identify independent associations, we applied the elastic net penalty to linear regression models. RESULTS: Two phthalate metabolites (MEHHP, MOiNP), perfluorooctanoic acid (PFOA), and p,p´-DDE were most consistently predictive of term birth weight based on elastic net penalty.......82 ng/g lipid), respectively; and MOiNP was associated with higher birth weight (46 g; 95% CI: -5, 97 per 2.22 ng/mL). CONCLUSIONS: This study suggests that several of the environmental contaminants, belonging to three chemical classes, may be independently associated with impaired fetal growth...

Bacteriophage resistance of a Delta thyA mutant of Lactococcus lactis blocked in DNA replication

DEFF Research Database (Denmark)

Pedersen, M.B.; Jensen, Peter Ruhdal; Janzen, T.

2002-01-01

, such as milk, there was no detectable d'ITP pool in the cells. Hence, DNA replication was abolished, and acidification by MBP71 was completely unaffected by the presence of nine different phages tested at a multiplicity of infection (MOI) of 0.1. Nonreplicating MBP71 must be inoculated at a higher level than...... was unaffected with MBP71 up to an MOI of 0.01. It was found that nonreplicating MBP71 produced largely the same products as CHCC373, though the acetaldehyde production of the former was higher....

The continued optical to mid-infrared evolution of V838 Monocerotis

Energy Technology Data Exchange (ETDEWEB)

Loebman, S. R. [Department of Astronomy, University of Michigan, 830 Dennison, 500 Church Street, Ann Arbor, MI 48109-1042 (United States); Wisniewski, J. P. [Homer L. Dodge Department of Physics and Astronomy, The University of Oklahoma, 440 W. Brooks Street, Norman, OK 73019 (United States); Schmidt, S. J. [Department of Astronomy, Ohio State University, 140 West 18th Avenue, Columbus, OH 43210 (United States); Kowalski, A. F. [NASA Postdoctoral Program Fellow, NASA Goddard Space Flight Center, Code 671, Greenbelt, MD 20771 (United States); Barry, R. K. [NASA Goddard Space Flight Center, Laboratory for Exoplanets and Stellar Astrophysics, Code 667, Greenbelt, MD 20771 (United States); Bjorkman, K. S. [Ritter Observatory, MS #113, Department of Physics and Astronomy, University of Toledo, Toledo, OH 43606-3390 (United States); Hammel, H. B. [AURA, 1212 New York Avenue NW, Suite 450, Washington, DC 20005 (United States); Hawley, S. L.; Szkody, P. [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195 (United States); Hebb, L. [Department of Physics, Hobart and William Smith Colleges, 300 Pulteney Street, Geneva, NY 14456 (United States); Kasliwal, M. M. [The Observatories, Carnegie Institution for Science, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); Lynch, D. K.; Russell, R. W. [The Aerospace Corporation, M2-266, P.O. Box 92957, Los Angeles, CA 90009-29257 (United States); Sitko, M. L., E-mail: sloebman@umich.edu [Department of Physics, University of Cincinnati, Cincinnati OH 45221 (United States)

2015-01-01

The eruptive variable V838 Monocerotis (V838 Mon) gained notoriety in 2002 when it brightened nine magnitudes in a series of three outbursts and then rapidly evolved into an extremely cool supergiant. We present optical, near-infrared (near-IR), and mid-IR spectroscopic and photometric observations of V838 Mon obtained between 2008 and 2012 at the Apache Point Observatory 3.5 m, NASA IRTF 3 m, and Gemini South 8 m telescopes. We contemporaneously analyze the optical and IR spectroscopic properties of V838 Mon to arrive at a revised spectral type L3 supergiant and effective temperature T{sub eff}∼2000–2200 K. Because there are no existing optical observational data for L supergiants, we speculate that V838 Mon may represent the prototype for L supergiants in this wavelength regime. We find a low level of Hα emission present in the system, consistent with interaction between V838 Mon and its B3V binary; however, we cannot rule out a stellar collision as the genesis event, which could result in the observed Hα activity. Based upon a two-component blackbody fit to all wavelengths of our data, we conclude that, as of 2009, a shell of ejecta surrounded V838 Mon at a radius of R=263±10 AU with a temperature of T=285±2 K. This result is consistent with IR interferometric observations from the same era and predictions from the Lynch et al. model of the expanding system, which provides a simple framework for understanding this complicated system.

The continued optical to mid-infrared evolution of V838 Monocerotis

International Nuclear Information System (INIS)

Loebman, S. R.; Wisniewski, J. P.; Schmidt, S. J.; Kowalski, A. F.; Barry, R. K.; Bjorkman, K. S.; Hammel, H. B.; Hawley, S. L.; Szkody, P.; Hebb, L.; Kasliwal, M. M.; Lynch, D. K.; Russell, R. W.; Sitko, M. L.

2015-01-01

The eruptive variable V838 Monocerotis (V838 Mon) gained notoriety in 2002 when it brightened nine magnitudes in a series of three outbursts and then rapidly evolved into an extremely cool supergiant. We present optical, near-infrared (near-IR), and mid-IR spectroscopic and photometric observations of V838 Mon obtained between 2008 and 2012 at the Apache Point Observatory 3.5 m, NASA IRTF 3 m, and Gemini South 8 m telescopes. We contemporaneously analyze the optical and IR spectroscopic properties of V838 Mon to arrive at a revised spectral type L3 supergiant and effective temperature T eff ∼2000–2200 K. Because there are no existing optical observational data for L supergiants, we speculate that V838 Mon may represent the prototype for L supergiants in this wavelength regime. We find a low level of Hα emission present in the system, consistent with interaction between V838 Mon and its B3V binary; however, we cannot rule out a stellar collision as the genesis event, which could result in the observed Hα activity. Based upon a two-component blackbody fit to all wavelengths of our data, we conclude that, as of 2009, a shell of ejecta surrounded V838 Mon at a radius of R=263±10 AU with a temperature of T=285±2 K. This result is consistent with IR interferometric observations from the same era and predictions from the Lynch et al. model of the expanding system, which provides a simple framework for understanding this complicated system.

Pop / Mart Juur

Index Scriptorium Estoniae

Juur, Mart, 1964-

2002-01-01

Heliplaatidest Nancy Sinatra "The Very Best Of". A-ha "Lifelines". Danny Krivit "Grass Roots". Frank Sinatra "Romance". Armand Van Helden "Gandhi Khan". Elvis Costello "When I Was Cruel". Erinevad esinejad "Audiolounge". Michael Bolton "Only A Woman Like You". Sheryl Crow "C'mon, C'mon"

Les tumeurs malignes primitives de l’intestin grèle: Aspects cliniques et thérapeutiques de 27 patients

Directory of Open Access Journals (Sweden)

Abahssain Halima

2011-03-01

Full Text Available Les tumeurs malignes de l'intestin grèle (TMPIG sont des tumeurs rares. Elles représentent 1 à 5% de toutes les tumeurs du tube digestif. Elles sont caractérisées par une hétérogénéité anatomopathologique et une symptomatologie pauvre et non spécifique entrainant ainsi un retard diagnostic, des difficultés Thérapeutiques et donc un mauvais pronostic. Nous rapportant les caractéristiques épidémiologiques, diagnostiques et thérapeutiques ainsi que la survie des patients atteints des TMIG au sein de l’institut national d’oncologie de Rabat. Il s’agit d’une analyse rétrospective des dossiers cliniques des 27 patients ayant le diagnostic de tumeurs malignes de l’intestin grèle admis dans notre institut entre 1998 et 2002. L’âge médian était de 46 ans (15-70 ans. Le délai médian de diagnostic était de 6 mois (0-96 mois. La douleur abdominale était le symptôme le plus fréquent (77.8%. L’étude anatomopathologique a montré 63% de lymphome non Hodgkinie, 14.8% d’adénocarcinome, 7.4% de tumeur stromale, 7.4% de carcinome neuroendocrine et 7.4% de sarcome intestinal. Vingt patients (76. 9% ont eu une résection chirurgicale et 14 patients (53. 8% ont eu une chimiothérapie en fonction du stade de la maladie et du type histologique. Après un recul médian de 11.6 mois, la survie globale après 12 mois était de 44.4% et la médiane de survie était de 11.6 mois. Les tumeurs malignes de l’intestin grèle sont rares. Leur diagnostic est tardif limitant ainsi la prise en charge thérapeutique curative. Les cliniciens doivent ètre avertis des symptômes gastro-intestinaux non spécifiques

UAB "Mažeikių šilumos tinklai" veiklos ir perspektyvų ekonominis vertinimas

OpenAIRE

Ligeikis, Linas; Jurkus, Jonas

2009-01-01

Magistro darbe analizuojamas UAB ,,Mažeikių šilumos tinklai’’ (toliau tekste – įmonė) veiklos efektyvumas 2003 – 2007 metais, pateikiamas 2008 – 2010 metų perspektyvų vertinimas, įgalinantis priimti praktinį sprendimą gerinant įmonės finansinę padėtį (gamtinių dujų panaudojimas) bei užtikrinant veiklos stabilumą (įskaitant vartotojų nepertraukiamą aprūpinimą šilumos energija) – kogeneracinės jėgainės įdiegimą. Darbe pateikiamos įmonės ekonominių rodiklių (finansinio stabilumo, likvidumo, kome...

“Vasaknų dvaro” alaus įvedimo į rinką rinkodaros strategijos formavimas

OpenAIRE

Kievišaitė, Inga

2009-01-01

Šiame darbe buvo suformuota naujai įsikūrusios įmonės “Vasaknų dvaras” alaus įvedimo į rinką rinkodaros strategija. Darbo tikslas buvo sukurti šią strategiją, o uždaviniai buvo išanalizuoti aplinką, kurioje veikia įmonė bei įmonės galimybes šioje aplinkoje; išsiaiškinti alaus gamybos ir pardavimo subtilybes, apklausiant šios srities ekspertus; pateikti sprendimus dėl produkto pozicionavimo ir rinkodaros komplekso elementų. Darbe buvo naudojamas kokybinis tyrimas – rinkos ekspertų giluminis in...

Study of thermodynamic stabilities of polytypes of n-C36H74 by solubility measurements and incoherent inelastic neutron scattering

Science.gov (United States)

Kubota, Hideki; Kaneko, Fumitoshi; Kawaguchi, Tatsuya

2005-01-01

The thermodynamic properties of the two polytypes of n-hexatriacontane (n-C36H74), single-layered structure Mon and double-layered structure Orth II have been investigated by means of solubility measurements and incoherent inelastic neutron scattering. The solubility measurements reveal that Orth II is more stable than Mon by 1.2 kJ/mol because of the advantage of larger entropy. The neutron scattering measurements show that the vibrational modes of Orth II shift to the lower frequencies compared with those of Mon in the frequency region below 120 cm-1. The advantage of Orth II in vibrational entropy due to the low-frequency shifts is estimated to be 9.6 J K-1/mol at 288 K under the harmonic approximation, which nearly agrees with the entropy difference of 6.8 J K-1/mol between Mon and Orth II determined by solubility measurements. These results suggest that the difference in vibrational entropy due to low-frequency modes mainly contributes to the relative thermodynamic stabilities of polytypic structures of long-chain compounds. From the frequency of methyl torsional mode, it is suggested that the cohesive force at the lamellar interface is stronger in Mon than in Orth II.

Transarterial chemoperfusion of the pelvis. Results in symptomatic locally recurrent tumors and lymph node metastases; Transarterielle Chemoperfusion des Beckens. Ergebnisse bei symptomatischen Rezidivtumoren und Lymphknotenmetastasen

Energy Technology Data Exchange (ETDEWEB)

Vogl, T.J.; Zangos, S.; Eichler, K.; Balzer, J.O.; Bauer, R.W. [Inst. fuer Diagnostische und Interventionelle Radiologie, J. W. Goethe-Univ. Frankfurt (Germany); Jacob, U.; Keilhauer, R. [Fachklinik fuer Innere Medizin, Leonardis-Klinik, Bad Heilbrunn (Germany)

2007-11-15

/5, and 1/3 of cases (clinical response rate: 54%). Radiologically, 4/24 (17%) patients showed PR, 12/24 (50%) SD, and 8/24 (34%) PD (tumor control (PR + SD): 67% of cases). Tumor response (median survival since first TACP) was as follows: colorectal: 2 PR, 7 SD, 2 PD (11.5 months), ovarian: 1 SD, 2 PD (8.5 mon), cervical: 1 PR, 1 SD (6 mon), breast: 2 SD (6 mon), gastric: 1 PD (11 mon), adrenal gland: 1 PD (12 mon), anal: 1 PD (10 mon), prostate: 1 PD (20 mon), Gartner's duct: 1 PR (20 mon), renal cell carcinoma: 1 SD (10 mon). (orig.)

Infrared spectroscopic study on polytypic transformation of growing single crystal of n-hexatriacontane ( n-C 36H 74)

Science.gov (United States)

Kubota, Hideki; Kaneko, Fumitoshi; Kawaguchi, Tatsuya; Kawasaki, Masatsugu

2005-02-01

There are two polytypic structures, single-layered structure Mon and double-layered structure Orth II for the M 011 modification of n-hexatriacontane ( n-C 36H 74). The solution crystal growth of the two polytypes under controlled supersaturation was investigated by the oblique IR transmission method. As to the supersaturation dependence of growth behavior, there was a significant difference between the two polytypes. While the overgrowth of Orth II took place on the (0 0 1) face of the Mon crystal at moderate supersaturations, the overgrowth of Mon on the Orth II crystals was not confirmed at any supersaturations below 0.30. The growth rate of Mon showed about a second-order dependence on supersaturation, whereas that of Orth II showed a first-order dependence. The growth mechanism of the M 011 modification and the cause for the one-way overgrowth were deduced on the basis of the thermodynamical stabilities and the supersaturation dependence of the growth rates.

Discontinuous drainage systems formed by highland precipitation and ground-water outflow in the Navua Valles and southwest Hadriacus Mons regions, Mars

Science.gov (United States)

Hargitai, H. I.; Gulick, V. C.; Glines, N. H.

2017-09-01

The Navua Valles are systems of paleodrainages located north of Dao Vallis, which empty into Hellas Planitia, the largest impact basin on Mars. In this study, we mapped and characterized the Navua Valles Region's individual drainage systems, including drainages along the southwestern flank of Hadriacus Mons, and one valley network from the same source as Navua Valles but flowing in the opposite direction. The major drainage systems share morphological characteristics common to both outflow channels and valley networks. The slopes in this region are dissected by two major Navua drainage systems (here Navua A* and B*) and several shorter, sub-parallel valleys formed on the highest gradient (approximately 20 m/km [1.15°]) slopes, at the lowest part of Hellas Basin's rim. The two major drainage systems originate in the highlands, and empty into the basin. Our mapping suggests that water in Navua Valles reached the basin floor in a complicated descent and included several episodes of surface ponding, surface runoff, infiltration, subsurface flow and subsequent outflow. The most prominent channel system, Navua A, forms a repetitive sequence of deep incision into bedrock, followed by a transition into broad channels in erodible materials, and then into unconfined deposits. This successive erosion-transport-deposition sequence continues to repeat along the valley's entire length forming a discontinuous pattern that is consistent with classical fluvial process models. The channels cut into volcanic plains likely emplaced from the formation of Tyrrhenus and Hadriacus Montes. The dendritic source valleys of Navua A originate from the rim of a highland crater while the rest of this subsystem consists of a single, discontinuous channel which is consistent with a single water source zone that likely supplied water for all channels downslope. These drainages may have formed as discontinuous channels, revealing the potential existence of subsurface drainage pathways located

Evaluation of Saccharomyces cerevisiae fermentation product as an alternative to monensin on growth performance, cost of gain, and carcass characteristics of heavy-weight yearling beef steers.

Science.gov (United States)

Swyers, K L; Wagner, J J; Dorton, K L; Archibeque, S L

2014-06-01

Two hundred fifty-two cross-bred yearling steers (406 ± 24 kg BW) were used in a completely randomized block design with a 2 × 2 factorial arrangement of treatments (7 pens/treatment) to evaluate the effects of dietary Saccharomyces cerevisiae fermentation product (SFP) and monensin (MON) on growth performance and carcass characteristics. Dietary treatments arranged as a 2 × 2 factorial were 1) with or without SFP and 2) with or without MON. Finishing diets contained 19.7% of DM as dried distiller's grains with solubles. Both SFP and MON were added in the total mixed ration in place of an equal amount of cornmeal (DM basis; target intake = 2.8 g of SFP and 33 mg of MON/kg of dietary DM). Each treatment group was offered ad libitum access to a transition ration from d 1 to 8 and then to the finishing ration from d 9 to 125. Body weights were collected on d 0, 28, 56, 84, 110, and 125. Initial and final BW was an average of 2-d weights (d -1 and 0 and d 124 and 125, respectively). Steers were shipped for harvest on d 125. Overall ADG was decreased (P = 0.03) in steers supplemented with SFP, but final BW was similar among treatments. Feeding SFP was associated with lighter (P < 0.01) HCW and a greater (P = 0.01) number of carcasses grading USDA Choice. Twelfth rib fat thickness was not affected by SFP (P = 0.82) or MON (P = 0.35), but numerical decreases in 12th rib fat thickness among cattle receiving SFP or MON alone contributed to a tendency (P = 0.07) for greater 12 rib fat thickness when SFP and MON were provided. There was no effect of treatment on cost of gain (P ≥ 0.21). The effects of SFP in the current study may have been limited in heavy yearling steers due to consumption of a finishing diet containing 19.7% dried distiller's grains with solubles.

High-intensity Interval training enhances mobilization/functionality of endothelial progenitor cells and depressed shedding of vascular endothelial cells undergoing hypoxia.

Science.gov (United States)

Tsai, Hsing-Hua; Lin, Chin-Pu; Lin, Yi-Hui; Hsu, Chih-Chin; Wang, Jong-Shyan

2016-12-01

Exercise training improves endothelium-dependent vasodilation, whereas hypoxic stress causes vascular endothelial dysfunction. Monocyte-derived endothelial progenitor cells (Mon-EPCs) contribute to vascular repair process by differentiating into endothelial cells. This study investigates how high-intensity interval (HIT) and moderate-intensity continuous (MCT) exercise training affect circulating Mon-EPC levels and EPC functionality under hypoxic condition. Sixty healthy sedentary males were randomized to engage in either HIT (3-min intervals at 40 and 80 % VO 2max for five repetitions, n = 20) or MCT (sustained 60 % VO 2max , n = 20) for 30 min/day, 5 days/week for 6 weeks, or to a control group (CTL) that did not received exercise intervention (n = 20). Mon-EPC characteristics and EPC functionality under hypoxic exercise (HE, 100 W under 12 % O 2 ) were determined before and after HIT, MCT, and CTL. The results demonstrated that after the intervention, the HIT group exhibited larger improvements in VO 2peak , estimated peak cardiac output (Q C ), and estimated peak perfusions of frontal cerebral lobe (Q FC ) and vastus lateralis (Q VL ) than the MCT group. Furthermore, HIT (a) increased circulating CD14 ++ /CD16 - /CD34 + /KDR + (Mon-1 EPC) and CD14 ++ /CD16 + /CD34 + /KDR + (Mon-2 EPC) cell counts, (b) promoted the migration and tube formation of EPCs, (c) diminished the shedding of endothelial (CD34 - /KDR + /phosphatidylserine + ) cells, and (d) elevated plasma nitrite plus nitrate, stromal cell-derived factor-1, matrix metalloproteinase-9, and vascular endothelial growth factor-A concentrations at rest or following HE, compared to those of MCT. In addition, Mon-1 and -2 EPC counts were directly related to VO 2peak and estimated peak Q C , Q FC , and Q VL . HIT is superior to MCT for improving hemodynamic adaptation and Mon-EPC production. Moreover, HIT effectively enhances EPC functionality and suppresses endothelial injury undergoing hypoxia.

The Kinetics of Swinging a Baseball Bat.

Science.gov (United States)

Crisco, Joseph J; Osvalds, Nikolas J; Rainbow, Michael J

2018-04-13

The purpose of this study was to compute the three-dimensional kinetics required to swing three youth baseball bats of varying moments of inertia (MOI). 306 swings by 22 male players (13-18 yrs.) were analyzed. Inverse dynamics with respect to the batter's hands were computed given the known kinematics and physical properties of the bats. We found that peak force increased with larger bat MOI and was strongly correlated with bat tip speed. In contrast, peak moments were weakly correlated with bat MOI and bat tip speed. Throughout the swing, the force applied to the bat was dominated by a component aligned with the long axis of the bat and directed away from the bat knob, while the moment applied to the bat was minimal until just prior to ball impact. These results indicate that players act to mostly "pull" the bat during their swing until just prior to ball impact, at which point they rapidly increase the moment on the bat. This kinetic analysis provides novel insight into the forces and moments used to swing baseball bats.

Trajet entre le réel et la fiction.

Directory of Open Access Journals (Sweden)

Véronique Mauron

2011-04-01

Full Text Available Au départ, il y a un contrat: un trajet en taxi est offert à un habitant de Sao Paulo en contrepartie d’une histoire racontée. C’est l’idée directrice du film, proposée par l’artiste Fabiana de Barros au cinéaste suisse Michel Favre. À l’arrière d’une voiture, se trouve l’artiste qui accueille un passager et qui lui soumet, en guise de support mental, une image que le spectateur ne voit pas. Cette image déclenche la prise de paroles, le trajet peut commencer dans ...

Le paysage atlantique dans Lettres à ma fille de Jean Désy. Entre projection et plongée

OpenAIRE

Myriam Marcil-Bergeron

2015-01-01

L’écrivain-voyageur Jean Désy raconte dans Lettres à ma fille (1997) sa première navigation hauturière, qui consiste en une traversée de l’océan Atlantique à la voile. Deux pôles orientent la représentation du grand large dans ce récit, soit la projection du voyageur vers le dehors et la plongée dans ses souvenirs des paysages nordiques et sylvestres. Par une approche géopoétique, cet article vise à examiner les effets du rythme et de la polysensorialité ainsi que la manière dont l’expérience...

L'Atlantide dans la série Stargate Atlantis (2004-2009) : un mythe remodelé par les valeurs spirituelles contemporaines

OpenAIRE

Lachance, Élisa

2011-01-01

Depuis Platon, l'Atlantide n'a pas cessé de fasciner et a toujours représenté un terrain fertile pour l'imaginaire. Le mythe a été repris, recomposé et remodelé de multiples manières, de la théosophie de Mme Blavatsky jusqu'aux spiritualités contemporaines. Ce n'est donc pas un hasard si la télésérie Stargate Atlantis s'en inspire directement en l'adaptant à la mentalité d'aujourd'hui. On y raconte qu'il y a 10 000 ans, les Anciens auraient quitté l'Atlantide pour revenir sur Terre. La menace...

Benjamin Loveluck, Réseaux, libertés et contrôle. Une généalogie politique d’internet

OpenAIRE

Atten, Michel

2017-01-01

Dans ce livre issu de sa thèse, Benjamin Loveluck nous propose de rendre compte du succès d’internet — il est profondément intégré à notre vie quotidienne — en insistant sur le fait qu’il continue à incarner un certain idéal comme vecteur de transformations sociales. Il en fait une lecture qui se distingue radicalement de la « belle histoire » déterministe encore racontée de façon dominante, assure-t-il : internet comme fruit de la cascade d’innovations technologiques ponctuée par des étapes ...

Dork Zabunyan, Passages de l'histoire

OpenAIRE

Morisset, Vanessa

2014-01-01

Dans les deux essais de ce petit livre, rassemblés pour entrer en résonnance selon le principe de la collection Faux raccord, Dork Zabunyan s'interroge sur la manière dont le cinéma peut contribuer à écrire l'histoire, à l'heure d'Internet et des vidéos postées par milliers. Il s'intéresse en particulier aux films qui racontent les révolutions du Printemps arabe. Dans le premier texte rédigé pour la publication, l'auteur aborde la question à partir du projet d'un réalisateur tunisien visant à...

L’écriture du temps dans Robinson Crusoe

OpenAIRE

Bulckaen, Denise

2018-01-01

“Le récit est une séquence deux fois temporelle... il y a le temps de la chose-racontée et le temps du récit (temps du signifié et temps du signifiant)”. Cette citation se trouve au début du chapitre que Genette consacre à “Ordre” dans Figures III. Elle s'applique à de nombreux romans, mais elle est particulièrement intéressante quand on considère le roman de forme autobiographique. Le décalage entre “le temps du signifié” et “le temps du signifiant” est plus ou moins grand selon les romans. ...

Femme, genre et politique en Grèce archaïque et classique. Autour d’Artémise d’Halicarnasse, l’amazone qui a existé

Directory of Open Access Journals (Sweden)

Violaine Sébillotte Cuchet

2010-01-01

Full Text Available Le dossier regroupe divers travaux rédigés sur la thématique des rapports individu/cité déclinée sur l’axe de l’intégration dans une filiation politique naturalisante (notion de patris et dans une catégorie de sexe (homme/femme. Le manuscrit sur Artémise est un travail d’histoire sociale du culturel dans une démarche critique de genre. Hérodote raconte l’histoire de cette reine d’Halicarnasse en Carie qui, à la tête d’une flottille, tient tête aux Athéniens lors de la bataille de Salamine (...

Le point de vue, Cahiers de praxématique n° 41, coordonné par Alain Rabatel, Montpellier, 2003

Directory of Open Access Journals (Sweden)

2005-07-01

Full Text Available Ce numéro des Cahiers de praxématique est consacré au point de vue. Cette notion utilisée d’abord par la critique littéraire (Pouillon en 1946 est ensuite passée au champ de la linguistique du discours (Ducrot en 1984. Pour la narratologie, le PDV (point de vue « traite de la prise en charge des informations narratives ». Selon l’approche de Gérard Genette, qui lui a substitué le terme de focalisation, si c’est bien le narrateur qui raconte, les événements sont représentés soit à partir de...

L'apprentissage du quechua à l'INALCO : Cours de quechua avec Lydia CORNEJO ENDARA

OpenAIRE

Cornejo Endara , Lydia; De Pablo , Elisabeth; STOCKINGER , Peter; Legrand , Valérie

2008-01-01

Cette vidéo présente un cours de quechua à l'INALCO. Après nous avoir expliqué sa méthode personnelle d'apprentissage de la langue quechua, Lydia Cornejo Endara nous propose de la mettre en application lors d'un cours où les étudiants s'exercent à pratiquer la langue en chantant, en racontant des histoires ou en recréant des situations de la vie courante.La série "Enseigner et apprendre à parler le quechua" que nous vous proposons ici, n'est pas un séminaire à proprement parler, mais une séri...

Monsieur Tompkins s'explore lui-même aventures biologiques

CERN Document Server

Gamow, George

1970-01-01

L'éminent physicien George Gamow, aidé cette fois du biologiste Martynas Ycas, nous raconte, avec son talent et son humour bien connus, ce nouveau cycle des aventures de M. Tompkins. Après avoir suivi une série de conférences populaires, M. Tompkins fait la connaissance du conférencier, un professeur de physique de l'université, puis rencontre sa fille Maud et l'épouse. Il peut ainsi poursuivre en famille son initiation à la science. Guidé par son beau-père, il s'intéresse d'abord à la physique pure, puis à la biologie.

The efficiency of the advertising tools of the commercial enterprise

OpenAIRE

Česnulevičius, Kęstutis

2008-01-01

Magistro darbe tiriamas reklamos priemonių efektyvumas komercinėje įmonėje. Magistro darbo tyrimo objektas – UAB „Inarta“ reklamos priemonių efektyvumas. Magistro darbo tikslas – išnagrinėti reklamos efektyvumą UAB „Inarta“ ir parengti jos gerinimo planą. Darbo tyrimo hipotezė – reklamos priemonių efektyvumą lemia ne tik išlaidos reklamai, bet teisingas priemonių pasirinkimas įmonės veiklai reklamuoti. O taip pat teorinės ir praktinės sąsajos supratimas – kaip įmonė supranta šią sąsają ir kai...

The forecast of risk in business

OpenAIRE

Stapulionytė, Agnė

2007-01-01

Vienas iš darbo tikslų yra apžvelgti rizikos sąvokos aiškinimus, jos rūšis, veiksnius bei vertinimo ir analizės metodus. Šio darbo tyrimo tikslas – vertinti pasirinktos įmonės X riziką pagal finansinių ataskaitų duomenis. Siekiant įvertinti įmonės riziką ateičiai, darbe prognozuosime 2007 -2008 metams statistinius įmonės dydžius: nuosavo kapitalo vertę, grynąjį pelną, įsipareigojimus, turtą ir kt. Pagal realius ir prognozuotus duomenis skaičiuosime finansinius rodiklius. Prognozes atliksime p...

Gaston Roulleau et l’étude des effets de commerce ou la tension entre statistiques fiduciaires et conceptions métallistes

OpenAIRE

Baubeau, Patrice

2011-01-01

Gaston Roulleau, économiste à la Banque de France puis cadre dirigeant de cette maison, a légué aux chercheurs d’aujourd’hui des séries statistiques monétaires encore employées, en particulier sur l’émission et l’escompte des effets de commerce. Cette étude, réalisée à l’initiative de la Société de Statistique de Paris (SSP) et avec les moyens propres à la Banque de France, reflète non seulement les préoccupations économiques et monétaires de la SSP, mais encore les conceptions monétaires mét...

Autobiografismo e autoriflessività nei Diari di Tommaso Landolfi

DEFF Research Database (Denmark)

Cecchini, Leonardo

2012-01-01

LA BIERE DU PECHER, Rien va and Des mois – that is Tommaso Landolfi ’s so called diaries– are emblematic examples of the hybrid nature of Landolfi ’s writing with its delicate equilibrium between fiction and essay, myth-making and self-commentary. After a brief theoretical excursus on autobiograp......LA BIERE DU PECHER, Rien va and Des mois – that is Tommaso Landolfi ’s so called diaries– are emblematic examples of the hybrid nature of Landolfi ’s writing with its delicate equilibrium between fiction and essay, myth-making and self-commentary. After a brief theoretical excursus...

Editorial

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Muriel Verbeeck-Boutin

2007-10-01

Full Text Available Version françaisePorter un projet comme un enfant en soi : la métaphore est facile, sans doute. Et pourtant ! Quelle autre image employer, pour évoquer ces quelques mois tout entiers consacrés à mûrir une idée, à la concrétiser et la mettre en œuvre, jusqu’à sa parution, aujourd’hui. Neuf mois à éveiller des enthousiasmes (ou trouver des gens pour partager le mien, susciter des collaborations, nouer des partenariats, mettre en œuvre une structure, dessiner une image, écrire, relire, corriger...

Los monólogos humorísticos en la clase de e/le: análisis lingüístico y didáctico

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A. Re

2012-08-01

Full Text Available ESLos numerosos estudios en lingüística aplicada sobre motivación y enseñanza de lenguas llevados a cabo en los últimos años, juntos con el asentamiento definitivo del enfoque comunicativo en la praxis didáctica, demuestran que el empleo del texto humorístico en las clases de lengua extranjera puede convertirse en una herramienta de gran utilidad. Tanto es así que no solo la creación de manuales de español como lengua extranjera, sino también las numerosas aportaciones y contribuciones online de material didáctico se basan, cada vez más, en la explotación de textos auténticos, escritos y orales, del registro cómico y humorístico. Sin embargo, cualquier profesor de español como lengua extranjera (E/LE habrá experimentado cierto grado de frustración al “llevar a clase el humor español” sin alcanzar los resultados esperados. Las razones de aparente fracaso pueden depender de distintos factores, pero sobre todo obedecen a la variedad de contextos de aprendizaje y a los distintos tipos de alumnado. El manejo de materiales audiovisuales que incluyan prácticas de humor presenta evidentes ventajas, pero también numerosas dificultades.El objetivo de este artículo es buscar un punto de contacto entre el género humorístico y la enseñanza de E/LE. A partir de ejemplos de monólogos de programas de humor españoles, se destacarán algunos problemas y ventajas relacionados con la presentación didáctica de este tipo de textos: la inserción de unidades fraseológicas, los referentes socioculturales y la transgresión lingüística o corrección política, entre otros. De la misma manera, se subrayará la importancia de la explotación de dicho género textual en las clases de E/LE con el fin de afianzar algunas competencias o destrezas recogidas por los marcos teóricos internacionales y que, sin embargo, no se suelen incorporar a la práctica del aula. También se hará referencia a la formación del profesor y a su tarea de

NeuroKinect: A Novel Low-Cost 3Dvideo-EEG System for Epileptic Seizure Motion Quantification.

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João Paulo Silva Cunha

Full Text Available Epilepsy is a common neurological disorder which affects 0.5-1% of the world population. Its diagnosis relies both on Electroencephalogram (EEG findings and characteristic seizure-induced body movements--called seizure semiology. Thus, synchronous EEG and (2Dvideo recording systems (known as Video-EEG are the most accurate tools for epilepsy diagnosis. Despite the establishment of several quantitative methods for EEG analysis, seizure semiology is still analyzed by visual inspection, based on epileptologists' subjective interpretation of the movements of interest (MOIs that occur during recorded seizures. In this contribution, we present NeuroKinect, a low-cost, easy to setup and operate solution for a novel 3Dvideo-EEG system. It is based on a RGB-D sensor (Microsoft Kinect camera and performs 24/7 monitoring of an Epilepsy Monitoring Unit (EMU bed. It does not require the attachment of any reflectors or sensors to the patient's body and has a very low maintenance load. To evaluate its performance and usability, we mounted a state-of-the-art 6-camera motion-capture system and our low-cost solution over the same EMU bed. A comparative study of seizure-simulated MOIs showed an average correlation of the resulting 3D motion trajectories of 84.2%. Then, we used our system on the routine of an EMU and collected 9 different seizures where we could perform 3D kinematic analysis of 42 MOIs arising from the temporal (TLE (n = 19 and extratemporal (ETE brain regions (n = 23. The obtained results showed that movement displacement and movement extent discriminated both seizure MOI groups with statistically significant levels (mean = 0.15 m vs. 0.44 m, p<0.001; mean = 0.068 m(3 vs. 0.14 m(3, p<0.05, respectively. Furthermore, TLE MOIs were significantly shorter than ETE (mean = 23 seconds vs 35 seconds, p<0.01 and presented higher jerking levels (mean = 345 ms(-3 vs 172 ms(-3, p<0.05. Our newly implemented 3D approach is faster by 87.5% in extracting body

NeuroKinect: A Novel Low-Cost 3Dvideo-EEG System for Epileptic Seizure Motion Quantification.

Science.gov (United States)

Cunha, João Paulo Silva; Choupina, Hugo Miguel Pereira; Rocha, Ana Patrícia; Fernandes, José Maria; Achilles, Felix; Loesch, Anna Mira; Vollmar, Christian; Hartl, Elisabeth; Noachtar, Soheyl

2016-01-01

Epilepsy is a common neurological disorder which affects 0.5-1% of the world population. Its diagnosis relies both on Electroencephalogram (EEG) findings and characteristic seizure-induced body movements--called seizure semiology. Thus, synchronous EEG and (2D)video recording systems (known as Video-EEG) are the most accurate tools for epilepsy diagnosis. Despite the establishment of several quantitative methods for EEG analysis, seizure semiology is still analyzed by visual inspection, based on epileptologists' subjective interpretation of the movements of interest (MOIs) that occur during recorded seizures. In this contribution, we present NeuroKinect, a low-cost, easy to setup and operate solution for a novel 3Dvideo-EEG system. It is based on a RGB-D sensor (Microsoft Kinect camera) and performs 24/7 monitoring of an Epilepsy Monitoring Unit (EMU) bed. It does not require the attachment of any reflectors or sensors to the patient's body and has a very low maintenance load. To evaluate its performance and usability, we mounted a state-of-the-art 6-camera motion-capture system and our low-cost solution over the same EMU bed. A comparative study of seizure-simulated MOIs showed an average correlation of the resulting 3D motion trajectories of 84.2%. Then, we used our system on the routine of an EMU and collected 9 different seizures where we could perform 3D kinematic analysis of 42 MOIs arising from the temporal (TLE) (n = 19) and extratemporal (ETE) brain regions (n = 23). The obtained results showed that movement displacement and movement extent discriminated both seizure MOI groups with statistically significant levels (mean = 0.15 m vs. 0.44 m, p<0.001; mean = 0.068 m(3) vs. 0.14 m(3), p<0.05, respectively). Furthermore, TLE MOIs were significantly shorter than ETE (mean = 23 seconds vs 35 seconds, p<0.01) and presented higher jerking levels (mean = 345 ms(-3) vs 172 ms(-3), p<0.05). Our newly implemented 3D approach is faster by 87.5% in extracting body

Nano-Micelle of Moringa Oleifera Seed Oil Triggers Mitochondrial Cancer Cell Apoptosis

Science.gov (United States)

Abd-Rabou, Ahmed A; Zoheir, Khairy M A; Kishta, Mohamed S; Shalby, Aziza B; Ezzo, Mohamed I

2016-01-01

Cancer, a worldwide epidemic disease with diverse origins, involves abnormal cell growth with the potential to invade other parts of the body. Globally, it is the main cause of mortality and morbidity. To overcome the drawbacks of the commercially available chemotherapies, natural products-loaded nano-composites are recommended to improve cancer targetability and decrease the harmful impact on normal cells. This study aimed at exploring the anti-cancer impacts of Moringa oleifera seed oil in its free- (MO) and nano-formulations (MOn) through studying whether it mechanistically promotes mitochondrial apoptosis-mediating cell death. Mitochondrial-based cytotoxicity and flow cytometric-based apoptosis analyses were performed on cancer HepG2, MCF7, HCT 116, and Caco-2 cell lines against normal kidney BHK-21 cell line. The present study resulted that MOn triggered colorectal cancer Caco-2 and HCT 116 cytotoxicity via mitochondrial dysfunction more powerful than its free counterpart (MO). On the other side, MOn and MO remarkably induces HCT 116 mitochondrial apoptosis, while sparing normal BHK-21 cells with minimal cytotoxic effect. The present results concluded that nano-micelle of Moringa oleifera seed oil (MOn) can provide a novel therapeutic approach for colorectal and breast cancers via mitochondrial-mediated apoptosis, while sparing normal and even liver cancer cells a bit healthy or with minimal harmful effect. Intriguingly, MOn induced breast cancer not hepatocellular carcinoma cell death. PMID:28032498

Administrative claims analysis of asthma-related health care utilization for patients who received inhaled corticosteroids with either montelukast or salmeterol as combination therapy.

Science.gov (United States)

Allen-Ramey, Felicia C; Bukstein, Don; Luskin, Allan; Sajjan, Shiva G; Markson, Leona E

2006-05-01

To compare asthma-related health care resource utilization among a matched cohort of asthma patients using inhaled corticosteroids (ICSs) plus either montelukast (MON) or salmeterol (SAL) as combination therapy for asthma, during a time prior to the availability of fixed-dose combinations of ICS/SAL. A retrospective analysis using the PHARMetrics patient-centric claims database was conducted for the period preceding the market introduction of combination fluticasone-SAL in September 2000. Patients had to meet the following criteria for inclusion in the study: they had to be between the ages of 4 and 55 years; they had to have been continuously enrolled for 2 years; they had to have initiated ICS/MON or ICS/SAL therapy between July 1, 1998, and June 30, 1999; and they had to have had either (a) a diagnosis of asthma (based on International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes of 493.xx) for 2 outpatient visits, 1 or more emergency department (ED) visits, or 1 or more hospitalizations within 1 year or (b) pharmacy claim records that contained a National Drug Code for an antiasthma medication (betaagonist, theophylline, ICS, cromolyn, or leukotriene) 2 or more times within 1 year. ICS/MON and ICS/SAL patients were matched 1 to 1 on age and propensity score. Outcomes included asthma-related hopitalizations and ED visits with ICD-9-CM codes of 493.xx, and oral corticosteroid (OCS) fills and short-acting beta-agonist (SABA) fills. Multivariate regression analyses were performed. Subgroup analyses based on sequential or concurrent initiation of combination therapy were also conducted. A total of 1,216 patients were matched (ICS/MON = 608; ICS/SAL= 608). Decreased odds of ED visits and/or hospitalizations were observed with ICS/MON (adjusted odds ratio [OR] = 0.58; 95% confidence interval [CI], 0.35- 0.98) versus ICS/SAL. The odds of postindex OCS fills were not different for ICS/MON and ICS/SAL patients (adjusted OR = 1.04; 95

Cryptosporidiosis and its genotypes among children attending Moi ...

African Journals Online (AJOL)

Objectives: To determine the prevalence of cryptosporidiosis and the associated factors, and characterise the Cryptosporidium isolates from children aged five years and less with diarrhoea. Design: A prospective cross-sectional study. Setting: This was a health facility and laboratory based study. Screening for

Actividad cultural de los capitulares de la catedral de Calahorra (1045-1257. De “scriptorium” monástico a “studium” catedralicio

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Tomás SÁENZ DE HARO

2009-12-01

Full Text Available RESUMEN: Esta pequeña investigación analiza las realidades culturales en el cabildo catedralicio de Calahorra a partir de la restauración de la Iglesia calagurritana, tras la reconquista de la ciudad en 1045, hasta la definitiva cristalización del organigrama capitular a mediados del siglo XIII. Relacionamos la evolución de las actividades culturales capitulares, desde el scriptorium de carácter monástico al studium característico de un cabildo secularizado, con la dinámica interna de la propia institución capitular, nacida como una comunidad de vida que lentamente evoluciona hacia lo que será el modelo organizativo clásico durante las edades media y moderna. Al mismo tiempo, pretendemos aproximarnos al nivel cultural de la sede, tanto en sus realizaciones como en la formación intelectual adquirida por sus miembros. De este modo, concluimos la interesante vitalidad del scriptorium durante los primeros años, situación que contrasta con el limitado desarrollo del studium y con la modesta preparación intelectual de los capitulares calagurritanos de la primera mitad del siglo XIII.ABSTRACT: The content of this brief research work is the analysis of the cultural activities within the heart of the cathedral chapter of Calahorra from the church restoration in 1045 to the eventual consolidation of its organizational structure by the middle of the 13th century. We connect the development of such cultural activity, from a monastic-like scriptorium to an studium characteristic of the secular background of the cathedrals, with the own internal dynamics of the chapter institution, born as a life community and slowly evolving into a classical related organization chart during the medieval and modern age. At the same time, we also inquire into the level of cultural tasks of the see, both their standard of production as well as the training of its members. This way, we conclude an interesting vitality of the scriptorium in its early years, a

Inelastic neutron scattering study on the polytypism of even-numbered n-alkanes

Science.gov (United States)

Kubota, Hideki; Kaneko, Fumitoshi; Kawaguchi, Tatsuya

2005-02-01

The thermodynamic properties of the two polytypes of n-hexatriacontane ( n- C36H74), single-layered structure Mon and double-layered structure Orth II, have been studied with incoherent inelastic neutron scattering and solubility measurements. The solubility measurements show that Orth II is more stable than Mon, because of its larger entropy. The neutron scattering measurements reveal that the vibrational modes of Orth II shift to the lower frequencies compared with those of Mon in the frequency region below 120 cm-1. The vibrational modes in this region make a dominant contribution to the vibrational entropy of a system, and the advantage of Orth II in vibrational entropy due to the low-frequency shifts is estimated to be 7.8 J K-1 mol-1 at 288 K under the harmonic approximation, which is in good agreement with the entropy difference between Mon and Orth II determined by solubility measurements. These results suggest that the relative stability of polytypic structures of long-chain compounds is mainly determined by the vibrational entropy of the low-frequency modes.

Les phlébotomes (Diptera-Psychodidae de l'île de Chypre.II - Presence de Leishmania (Leishmania infantum Nicolle, 1908 (zymodeme MON 1 chez Phlebotomus (Larroussius tobbi Adler et Theodor, 1930

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Léger N.

2000-06-01

Full Text Available Dans le foyer leishmanien cypriote, les auteurs ont disséqué 2910 femelles de phlébotomes appartenant à 11 espèces : Phlebotomus papatasi, P. sergenti, P. jacusieli, P. alexandri, P. tobbi, P. galilaeus, P. mascittii, P. economidesi, Sergentomyia fallax, S. minuta et S. azizi . Les deux larroussius (P. galilaeus et P. tobbi sont les espèces les plus abondantes. Elles représentent plus de 60 % des captures réalisées avec des pièges CDC. Des promastigotes ont été observées chez un seul spécimen appartenant à l'espèce P. tobbi. Elles ont été mises en culture puis identifiées selon la méthode isoenzymatique. La souche de Leishmania isolée appartient à l'espèce Leishmania infantum, zymodème MON 1. Le même zymodème a été aussi isolé et identifié chez quatre chiens de l'île. En l'absence des vecteurs habituels de L. infantum dans l'est méditerranéen (P. neglectus ef P. syriacus et en raison de sa répartition à Chypre, P. tobbi constitue vraisemblablement un bon vecteur local. Sa faible anthropophilie expliquerait peut-être le très faible nombre de cas humains. Le rôle de P. galilaeus dans la transmission de la leishmaniose à Chypre reste à préciser.

Voix-off et voix(e narrative : la conscience entre les lignes dans l’œuvre de Arnaud Desplechin

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Marie-Anne Lieb

2012-07-01

Full Text Available L’œuvre d’Arnaud Desplechin est particulièrement intéressante à bien des égards et a fortiori pour sa virtuosité narrative. Cinéma romanesque et introspectif, la narration passe entre autres, par l’usage savant de la voix-off comme mode d’énonciation ou par celui des voix (es narratives proches de la « moving box » propre à Terence Malick. Des aventures spirituelles, au marivaudage et aux quêtes existentielles, leur utilisation au sein de la filmographie confère aux personnages une tendance à l’affabulation. L’enjeu réside en ce que le cinéaste cherche à raconter une histoire autant que ses personnages tentent de se raconter eux-mêmes. Recomposant la complexité humaine, Desplechin déploie un cinéma dans lequel la voix-off ouvrent un peu plus les possibles narratifs en forme d’insularité humaine.Arnaud Desplechin’s work is particularly interesting in many respects but especially so for his narrative virtuosity. In his style of cinema, which combines both story-telling and introspection, the plot unfolds by the wise use, amongst other things, of voice-over as a means of statement or by narrative voices similar to the “moving box” technique used by Terence Malick. The use of such techniques, ranging from spiritual adventures to light hearted banter and existential quests, in the heart of filmography can give the impression that characters do not ring true. For the film-maker, the problem is how to balance the unfolding of the overall story-line with the exteriorisation of each character’s personal thoughts. By rearranging human complexity, Desplechin develops a cinema in which the voice-over progressively opens up the possible narratives reflecting human insularity.

Higher Complexity of Infection and Genetic Diversity of Plasmodium vivax Than Plasmodium falciparum across all Malaria Transmission Zones of Papua New Guinea

Science.gov (United States)

Fola, Abebe A.; Harrison, G. L. Abby; Hazairin, Mita Hapsari; Barnadas, Céline; Hetzel, Manuel W.; Iga, Jonah; Siba, Peter M.; Mueller, Ivo; Barry, Alyssa E.

2017-01-01

Plasmodium falciparum and Plasmodium vivax have varying transmission dynamics that are informed by molecular epidemiology. This study aimed to determine the complexity of infection and genetic diversity of P. vivax and P. falciparum throughout Papua New Guinea (PNG) to evaluate transmission dynamics across the country. In 2008–2009, a nationwide malaria indicator survey collected 8,936 samples from all 16 endemic provinces of PNG. Of these, 892 positive P. vivax samples were genotyped at PvMS16 and PvmspF3, and 758 positive P. falciparum samples were genotyped at Pfmsp2. The data were analyzed for multiplicity of infection (MOI) and genetic diversity. Overall, P. vivax had higher polyclonality (71%) and mean MOI (2.32) than P. falciparum (20%, 1.39). These measures were significantly associated with prevalence for P. falciparum but not for P. vivax. The genetic diversity of P. vivax (PvMS16: expected heterozygosity = 0.95, 0.85–0.98; PvMsp1F3: 0.78, 0.66–0.89) was higher and less variable than that of P. falciparum (Pfmsp2: 0.89, 0.65–0.97). Significant associations of MOI with allelic richness (rho = 0.69, P = 0.009) and expected heterozygosity (rho = 0.87, P < 0.001) were observed for P. falciparum. Conversely, genetic diversity was not correlated with polyclonality nor mean MOI for P. vivax. The results demonstrate higher complexity of infection and genetic diversity of P. vivax across the country. Although P. falciparum shows a strong association of these parameters with prevalence, a lack of association was observed for P. vivax and is consistent with higher potential for outcrossing of this species. PMID:28070005

Non-Intrusive Magneto-Optic Detecting System for Investigations of Air Switching Arcs

International Nuclear Information System (INIS)

Zhang Pengfei; Zhang Guogang; Dong Jinlong; Liu Wanying; Geng Yingsan

2014-01-01

In current investigations of electric arc plasmas, experiments based on modern testing technology play an important role. To enrich the testing methods and contribute to the understanding and grasping of the inherent mechanism of air switching arcs, in this paper, a non-intrusive detecting system is described that combines the magneto-optic imaging (MOI) technique with the solution to inverse electromagnetic problems. The detecting system works in a sequence of main steps as follows: MOI of the variation of the arc flux density over a plane, magnetic field information extracted from the magneto-optic (MO) images, arc current density distribution and spatial pattern reconstruction by inverting the resulting field data. Correspondingly, in the system, an MOI set-up is designed based on the Faraday effect and the polarization properties of light, and an intelligent inversion algorithm is proposed that involves simulated annealing (SA). Experiments were carried out for high current (2 kA RMS) discharge cases in a typical low-voltage switchgear. The results show that the MO detection system possesses the advantages of visualization, high resolution and response, and electrical insulation, which provides a novel diagnostics tool for further studies of the arc. (low temperature plasma)

Transportable data from non-target arthropod field studies for the environmental risk assessment of genetically modified maize expressing an insecticidal double-stranded RNA.

Science.gov (United States)

Ahmad, Aqeel; Negri, Ignacio; Oliveira, Wladecir; Brown, Christopher; Asiimwe, Peter; Sammons, Bernard; Horak, Michael; Jiang, Changjian; Carson, David

2016-02-01

As part of an environmental risk assessment, the potential impact of genetically modified (GM) maize MON 87411 on non-target arthropods (NTAs) was evaluated in the field. MON 87411 confers resistance to corn rootworm (CRW; Diabrotica spp.) by expressing an insecticidal double-stranded RNA (dsRNA) transcript and the Cry3Bb1 protein and tolerance to the herbicide glyphosate by producing the CP4 EPSPS protein. Field trials were conducted at 14 sites providing high geographic and environmental diversity within maize production areas from three geographic regions including the U.S., Argentina, and Brazil. MON 87411, the conventional control, and four commercial conventional reference hybrids were evaluated for NTA abundance and damage. Twenty arthropod taxa met minimum abundance criteria for valid statistical analysis. Nine of these taxa occurred in at least two of the three regions and in at least four sites across regions. These nine taxa included: aphid, predatory earwig, lacewing, ladybird beetle, leafhopper, minute pirate bug, parasitic wasp, sap beetle, and spider. In addition to wide regional distribution, these taxa encompass the ecological functions of herbivores, predators and parasitoids in maize agro-ecosystems. Thus, the nine arthropods may serve as representative taxa of maize agro-ecosystems, and thereby support that analysis of relevant data generated in one region can be transportable for the risk assessment of the same or similar GM crop products in another region. Across the 20 taxa analyzed, no statistically significant differences in abundance were detected between MON 87411 and the conventional control for 123 of the 128 individual-site comparisons (96.1%). For the nine widely distributed taxa, no statistically significant differences in abundance were detected between MON 87411 and the conventional control. Furthermore, no statistically significant differences were detected between MON 87411 and the conventional control for 53 out of 56 individual

Heisenberg 1901-1976 : le témoignage de sa femme

CERN Document Server

Heisenberg, Elisabeth

1990-01-01

Une femme raconte la vie de son mari, Werner Heisenberg, Prix Nobel de Physique 1932. Après une enfance heureuse, ce brillant étudiant fut l'élève d'Albert Einstein, Niels Bohr, Arnold Sommerfeld. Mais à l'époque de la montée du nazisme, le grand physicien refusa de quitter son pays, cautionnant ainsi le régime d'Hitler et participant à "l'effort de guerre", c'est-à-dire à la course à la bombe. Le témoignage d'Elisabeth Heisenberg bien que naturellement subjectif, permet de saisir les ressorts psychologiques du comportement d'un savant face aux terrifiantes réalités de son époque.

Fatou, Julia, Montel le grand prix des sciences mathématiques de 1918, et après

CERN Document Server

Audin, Michèle

2009-01-01

Comment Fatou et Julia ont inventA(c) ce que la (TM)on appelle aujourda (TM)hui les ensembles de Julia, avant, pendant et aprA]s la premiA]re guerre mondiale? La (TM)histoire est racontA(c)e, avec ses mathA(c)matiques, ses conflits, ses personnalitA(c)s. Elle est traitA(c)e A partir de sources nouvelles, et avec rigueur. On pourra sa (TM)y initier A la (TM)itA(c)ration des fractions rationnelles et A la dynamique complexe (ensembles de Julia, de Mandelbrot, ensembles-limites). Qui A(c)taient Pierre Fatou, Gaston Julia, Paul Montel? On y trouvera en particulier des informations sur un mathA(c)m

Les écritures féminines de la guerre d’Algérie : L’exemple de Maïssa Bey

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Khédidja Mokaddem

2009-03-01

Full Text Available L'histoire de la guerre d'Algérie que l'on ne peut pas encore mettre à distance, parce que les acteurs et les témoins sont encore là, ils sont porteurs de la mémoire et ils peuvent raconter, témoigner, cette histoire est encore prisonnière de passions encore vivaces, douloureuses le plus souvent. Cette histoire, suspecte de partialité parce qu'elle ne peut occulter les affects, beaucoup d'auteurs ont voulu la restituer, certains dans le cadre du simple témoignage, d'autres pour alimenter des récits « en contexte », nourris de souvenirs personnels ou d'autres récits.

Ἡ συνωμοσία τοῦ Κουρκούα στὸ «Βίο Βασιλείου»

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Βασιλική Ν. ΒΛΥΣΙΔΟΥ

1985-09-01

Full Text Available  Vassiliki VlyssidouLe complot de Kourkouas d'après la «Vie de Ba­sile» Selon l'avis de l'auteur, des raisons politiques ont poussé Constantin Porphyrogénète à raconter le complot de Kourkouas d'une façon sommaire. En le situant chronologiquement quelques années plus tôt et en passant sous silence des détails qui contribueraient à une appréciation objective ses dimensions, le Porphyrogénète s'éfforce de le séparer des circonstances politiques et sociales, qui dominaient à la fin du règne de Basile Ier

Ljudmila Ulitskaja, Daniel Stein, interprète

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Giulia Gigante

2010-02-01

Full Text Available L’œuvre, caractérisée par une rare intensité émotionnelle et une structure extrêmement complexe, narre une histoire vraie dans laquelle s’entremêlent tous les principaux événements dramatiques de l’Histoire du XXe siècle. Le Daniel du titre a donc réellement existé. Ljudmila Ulitskaja l’a rencontré par hasard il y a quinze ans et était, depuis lors, hantée par l’idée de raconter sa vie. Ulitskaja abandonne la narration linéaire qui caractérisait ses œuvres précédentes et opte pour une forme d...

1909

OpenAIRE

Kessler, Comte Harry

2017-01-01

Paris, 9 janvier 1909 Dernier jour de l’exposition Seurat. Fénéon m’y a présenté Henri Matisse, avec qui j’ai longuement parlé. Chez Seurat, il admire surtout « la pureté du dessin. Chez Seurat, je trouve que le dessin domine tout. » Il m’a raconté que Renoir n’aime pas Seurat, qu’il le trouve « trop systématique ». Matisse combat cette opinion. Nous avons parlé de Gustave Moreau, dont Matisse a été l’élève. J’ai demandé à Matisse par quoi s’expliquait l’influence de Moreau, alors que c’est u...

Quelques espèces nouvelles d’hispides de Sumatra appartenant au Musée de Leyde

NARCIS (Netherlands)

Gestro, R.

1897-01-01

Sur le point d’entreprendre l’étude des Hispides recueillies à Sumatra par M. le Doct. E. Modigliani, j’ai demandé à M. Ritsema, le savant conservateur de la collection d’insectes du Musée de Leyde, la communication de quelques espèces dans le but de faciliter mon travail. Mon aimable collègue a

Raconter les Highland Clearances : Fluctuations mémorielles et instrumentalisationde la mémoire

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Laurence GOURIEVIDIS

2011-06-01

Full Text Available Dans l’histoire écossaise moderne, peu d’événements ont autant de résonance et de charge émotionnelle que les évictions des paysans du Nord du pays et les conflits qu’elles engendrèrent entre le milieu du 18ème siècle et 1886, année où une loi garantissant l’accès à la terre à une partie de la paysannerie concernée limita considérablement le droit des propriétaires et mit un terme aux expulsions massives. Connus sous le nom de Highland Clearances, ces événementsn’ont rien perdu de leur pouvoir mobilisateur. Les adjectifs « contesté », ou « controversé » leur sont couramment appliqués ainsi qu’à leurs représentations, qu’elles soient littéraires ou historiques. Cet article s’appuie sur la notion de « mémoire culturelle », développée par Jan Assman, pour analyser le sens, les valeurs et la vision du monde cristallisés dans la mémoire collective des Clearances. S’attachant à l’historiographie des Clearances, à la production littéraire sur la période et à son appropriation politique, il met en lumière la cohérence et la stabilité de la mémoire culturelle des Clearances. Ces dernières sont, par conséquent, devenues un symbole puissant dans le discours politique écossais ; Nationalistes et Travaillistes écossais s’en sont emparés pour alimenter des argumentaires en faveur de la réforme de la propriété foncière, de l’accès à la terre, en résumé la démocratisation du système foncier.In Modern Scottish history, few events have had as much resonance and emotional charge as the Highland Clearances, i.e. the evictions of tenants and the social conflicts in northern Scotland and the Hebrides from the middle of the 18th century until 1886, when legislation put an end to large-scale removals by conferring security of tenure on crofters and considerably restricting landowning power. The Highland Clearances still retain much of their mobilizing power. The adjectives “contested” or “controversial” are recurrently applied to the events and their re-presentations, be they literary or historical. This article uses the notion of “cultural memory”, put forward by Jan Assman, to analyse the meaning, values and mind-set that the collective memory of the Clearances has come to encapsulate. It surveys the historiography of the Clearances, the literary production of the period and the political appropriation of the events, and brings to light the consistency and stability of the cultural memory of those events. As a result, the Clearances have become a potent symbol in Scottish political discourse, hijacked by Nationalist and Labour politicians alike to feed arguments in favour of the reform of land ownership and land access, in short the democratization of the land system.

The combined effects of irradiation and herpes simplex virus type 1 infection on an immortal gingival cell line

Science.gov (United States)

2014-01-01

Background Oral mucosa is frequently exposed to Herpes simplex virus type 1 (HSV-1) infection and irradiation due to dental radiography. During radiotherapy for oral cancer, the surrounding clinically normal tissues are also irradiated. This prompted us to study the effects of HSV-1 infection and irradiation on viability and apoptosis of oral epithelial cells. Methods Immortal gingival keratinocyte (HMK) cells were infected with HSV-1 at a low multiplicity of infection (MOI) and irradiated with 2 Gy 24 hours post infection. The cells were then harvested at 24, 72 and 144 hours post irradiation for viability assays and qRT-PCR analyses for the apoptosis-related genes caspases 3, 8, and 9, bcl-2, NFκB1, and viral gene VP16. Mann–Whitney U-test was used for statistical calculations. Results Irradiation improved the cell viability at 144 hours post irradiation (P = 0.05), which was further improved by HSV-1 infection at MOI of 0.00001 (P = 0.05). Simultaneously, the combined effects of infection at MOI of 0.0001 and irradiation resulted in upregulation in NFκB1 (P = 0.05). The combined effects of irradiation and HSV infection also significantly downregulated the expression of caspases 3, 8, and 9 at 144 hours (P = 0.05) whereas caspase 3 and 8 significantly upregulated in non-irradiated, HSV-infected cells as compared to uninfected controls (P = 0.05). Infection with 0.0001 MOI downregulated bcl-2 in non-irradiated cells but was upregulated by 27% after irradiation when compared to non-irradiated infected cells (P = 0.05). Irradiation had no effect on HSV-1 shedding or HSV gene expression at 144 hours. Conclusions HSV-1 infection may improve the viability of immortal cells after irradiation. The effect might be related to inhibition of apoptosis. PMID:25005804

Comparison of Human Sodium/Iodide Symporter (hNIS) Gene Expressions between Lentiviral and Adenoviral Vectors in Rat Mesenchymal Stem Cells

Energy Technology Data Exchange (ETDEWEB)

Park, So Yeon; Lee, Won Woo; Kim, Hyun Joo; Chung, June Key; Kim, Sang Eun [Seoul National University College of Medicine, Seoul (Korea, Republic of); Kim, Sung Jin; Lee, Heui Ran [Medical Research Center, Seoul National University, Seoul (Korea, Republic of)

2008-10-15

Quantitative comparison of transgene expression within stem cells between lentivirus and adenovirusmediated delivery systems has not been reported. Here, we evaluated the human sodium iodide symporter (hNIS) gene expression in rat mesenchymal stem cell (rMSC) transduced by lentivirus or adenovirus, and compared the hNIS expression quantitatively between the two delivery systems. Lentiviral-mediated hNIS expressing rMSC (lenti-hNIS-rMSC) was constructed by cloning hNIS gene into pLenti6/UbC/V5-DEST (Invitrogen) to obtain pLenti-hNIS, transducing rMSC with the pLenti-hNIS, and selecting with blasticidin for 3 weeks. Recombinant adenovirus expressing hNIS gene (Rad-hNIS) was produced by homologous recombination and transduction efficiency of Rad-hNIS into rMSC evaluated by Rad-GFP was 19.1{+-}4.7%, 54.0{+-}6.4%, 85.7{+-}8.7%, and 98.4{+-}1.3% at MOI 1, 5, 20, and 100, respectively. The hNIS expressions in lenti-hNIS-rMSC or adeno-hNIS-rMSC were assessed by immunocytochemistry, western blot, and I-125 uptake. Immunocytochemistry and western blot analyses revealed that hNIS expressions in lenti-hNIS-rMSC were greater than those in adeno-hNIS-rMSC at MOI 20 but lower than at MOI 50. However in vitro I-125 uptake test demonstrated that iodide uptake in lenti-hNIS-rMSC (29,704{+-}6,659 picomole/10{sup 6} cells) was greater than that in adeno-hNIS-rMSC at MOI 100 (6,168{+-}2,134 picomole/10{sup 6} cells). Despite lower amount of expressed protein, hNIS function in rMSC was greater by lentivirus than by adenovirus mediated expression. Stem cell tracking using hNIS as a reporter gene should be conducted in consideration of relative vector efficiency for transgene expression.

Mediterranean Thermohaline Response to Large-Scale Winter Atmospheric Forcing in a High-Resolution Ocean Model Simulation

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Cusinato, Eleonora; Zanchettin, Davide; Sannino, Gianmaria; Rubino, Angelo

2018-04-01

Large-scale circulation anomalies over the North Atlantic and Euro-Mediterranean regions described by dominant climate modes, such as the North Atlantic Oscillation (NAO), the East Atlantic pattern (EA), the East Atlantic/Western Russian (EAWR) and the Mediterranean Oscillation Index (MOI), significantly affect interannual-to-decadal climatic and hydroclimatic variability in the Euro-Mediterranean region. However, whereas previous studies assessed the impact of such climate modes on air-sea heat and freshwater fluxes in the Mediterranean Sea, the propagation of these atmospheric forcing signals from the surface toward the interior and the abyss of the Mediterranean Sea remains unexplored. Here, we use a high-resolution ocean model simulation covering the 1979-2013 period to investigate spatial patterns and time scales of the Mediterranean thermohaline response to winter forcing from NAO, EA, EAWR and MOI. We find that these modes significantly imprint on the thermohaline properties in key areas of the Mediterranean Sea through a variety of mechanisms. Typically, density anomalies induced by all modes remain confined in the upper 600 m depth and remain significant for up to 18-24 months. One of the clearest propagation signals refers to the EA in the Adriatic and northern Ionian seas: There, negative EA anomalies are associated to an extensive positive density response, with anomalies that sink to the bottom of the South Adriatic Pit within a 2-year time. Other strong responses are the thermally driven responses to the EA in the Gulf of Lions and to the EAWR in the Aegean Sea. MOI and EAWR forcing of thermohaline properties in the Eastern Mediterranean sub-basins seems to be determined by reinforcement processes linked to the persistency of these modes in multiannual anomalous states. Our study also suggests that NAO, EA, EAWR and MOI could critically interfere with internal, deep and abyssal ocean dynamics and variability in the Mediterranean Sea.

Tc depression and superconductor-insulator transition in molybdenum nitride thin films

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Ichikawa, F.; Makise, K.; Tsuneoka, T.; Maeda, S.; Shinozaki, B.

2018-03-01

We have studied that the Tc depression and the superconductor-insulator transition (SIT) in molybdenum nitride (MoN) thin films. Thin films were fabricated by reactive DC magnetron sputtering method onto (100) MgO substrates in the mixture of Ar and N2 gases. Several dozen MoN thin films were prepared in the range of 3 nm < thickness d < 60 nm. The resistance was measured by a DC four-probe technique. It is found that Tc decreases from 6.6 K for thick films with increase of the normal state sheet resistance {R}{{sq}}{{N}} and experimental data were fitted to the Finkel’stein formula using the bulk superconducting transition temperature Tc 0 = 6.45 K and the elastic scattering time of electron τ = 1.6 × 10‑16 s. From this analysis the critical sheet resistance Rc is found about 2 kΩ, which is smaller than the quantum sheet resistance R Q. This value of Rc is almost the same as those for 2D NbN films. The value of τ for MoN films is also the similar value for NbN films 1.0 × 10‑16 s, while Tc 0 is different from that for NbN films 14.85 K. It is indicated that the mechanism of SIT for MoN films is similar to that of NbN films, while the mean free path ℓ for MoN films is larger than that for NbN films.

Myths on Bi-direction Communication of Web 2.0 Based Social Networks: Is Social Network Truly Interactive?

Science.gov (United States)

2011-03-10

more and more social interactions are happening on the on-line. Especially recent uptake of the social network sites (SNSs), such as Facebook (http...Smart phones • Live updates within social networks • Facebook & Twitters Solution: WebMon for Risk Management Need for New WebMon for Social Networks ...Title: Myths on bi-direction communication of Web 2.0 based social networks : Is social network truly interactive

Multilocus microsatellite typing (MLMT of strains from Turkey and Cyprus reveals a novel monophyletic L. donovani sensu lato group.

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Evi Gouzelou

Full Text Available BACKGROUND: New foci of human CL caused by strains of the Leishmania donovani (L. donovani complex have been recently described in Cyprus and the Çukurova region in Turkey (L. infantum situated 150 km north of Cyprus. Cypriot strains were typed by Multilocus Enzyme Electrophoresis (MLEE using the Montpellier (MON system as L. donovani zymodeme MON-37. However, multilocus microsatellite typing (MLMT has shown that this zymodeme is paraphyletic; composed of distantly related genetic subgroups of different geographical origin. Consequently the origin of the Cypriot strains remained enigmatic. METHODOLOGY/PRINCIPAL FINDINGS: The Cypriot strains were compared with a set of Turkish isolates obtained from a CL patient and sand fly vectors in south-east Turkey (Çukurova region; CUK strains and from a VL patient in the south-west (Kuşadasi; EP59 strain. These Turkish strains were initially analyzed using the K26-PCR assay that discriminates MON-1 strains by their amplicon size. In line with previous DNA-based data, the strains were inferred to the L. donovani complex and characterized as non MON-1. For these strains MLEE typing revealed two novel zymodemes; L. donovani MON-309 (CUK strains and MON-308 (EP59. A population genetic analysis of the Turkish isolates was performed using 14 hyper-variable microsatellite loci. The genotypic profiles of 68 previously analyzed L. donovani complex strains from major endemic regions were included for comparison. Population structures were inferred by combination of bayesian model-based and distance-based approaches. MLMT placed the Turkish and Cypriot strains in a subclade of a newly discovered, genetically distinct L. infantum monophyletic group, suggesting that the Cypriot strains may originate from Turkey. CONCLUSION: The discovery of a genetically distinct L. infantum monophyletic group in the south-eastern Mediterranean stresses the importance of species genetic characterization towards better understanding

Correlations between topography and intraflow width behavior in Martian and terrestrial lava flows

Science.gov (United States)

Peitersen, Matthew N.; Crown, David A.

2000-02-01

Local correlations between topography and width behavior within lava flows at Puu Oo, Mount Etna, Glass Mountain, Cerro Bayo, Alba Patera, Tyrrhena Patera, Elysium Mons, and Olympus Mons were investigated. For each flow, width and slope data were both referenced via downflow distance as a sequence of points; the data were then divided into collections of adjacent three-point features and two-point segments. Four discrete types of analyses were conducted: (1) Three-point analysis examined positional correlations between width and slope features, (2) two-point analysis did the same for flow segments, (3) mean slope analysis included segment slope comparisons, and (4) sudden width behavior analysis measured abruptness of width changes. The distribution of types of correlations compared to random combinations of features and segments does not suggest a significant correlation between flow widths and local underlying slopes and indicates that for these flows at least, other factors have more influence on changes in width than changes in underlying topography. Mean slopes underlying narrowing, widening, and constant flow width segments were calculated. An inverse correlation between slope and width was found only at Mount Etna, where slopes underlying narrowing segments were greater than those underlying widening in 62% of the examined flows. For the majority of flows at Mount Etna, Puu Oo, and Olympus Mons, slopes were actually greatest under constant width segments; this may imply a topographically dependent resistance to width changes. The rate of change of width was also examined. Sudden width changes are relatively common at Puu Oo, Mount Etna, Elysium Mons, and Tyrrhena Patera and relatively rare at Glass Mountain, Cerro Bayo, Olympus Mons, and Alba Patera. After correction for mapping scale, Puu Oo, Mount Etna, Olympus Mons, and Alba Patera appear to fall on the same trend; Glass Mount exhibits unusually small amounts of sudden width behavior, and Tyrrhena Patera

On the calculation of complete dissociation curves of closed-shell pseudo-onedimensional systems via the complete active space method of increments

Energy Technology Data Exchange (ETDEWEB)

Fertitta, E.; Paulus, B. [Institut für Chemie und Biochemie, Freie Universität Berlin, Takustr. 3, 14195 Berlin (Germany); Barcza, G.; Legeza, Ö. [Strongly Correlated Systems “Lendület” Research Group, Wigner Research Centre for Physics, P.O. Box 49, Budapest (Hungary)

2015-09-21

The method of increments (MoI) has been employed using the complete active space formalism in order to calculate the dissociation curve of beryllium ring-shaped clusters Be{sub n} of different sizes. Benchmarks obtained through different quantum chemical methods including the ab initio density matrix renormalization group were used to verify the validity of the MoI truncation which showed a reliable behavior for the whole dissociation curve. Moreover we investigated the size dependence of the correlation energy at different interatomic distances in order to extrapolate the values for the periodic chain and to discuss the transition from a metal-like to an insulator-like behavior of the wave function through quantum chemical considerations.

(4-tert-Butylpyridinechlorido[hydrotris(3,5-dimethylpyrazol-1-ylborato]nitrosylmolybdenum(I dichloromethane monosolvate

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Jon A. McCleverty

2010-12-01

Full Text Available In the title compound, [Mo(C15H22BN6Cl(NO(C9H13N]·CH2Cl2, the MoI atom adopts a distorted MoClN5 octahedral geometry with the hydrotris(3,5-dimethylpyrazolylborate anion in an N,N′,N′′-tridentate tripodal (facial coordination mode. A 4-tert-butylpyrine ligand, chloride anion and a nitrosyl cation complement the coodination of the MoI atom and an intramolecular C—H...Cl hydrogen bond helps to stabilize the configuration of the complex molecule. The packing is stabilized by an intermolecular C—H...Cl hydrogen bond involving the complex molecule and the CH2Cl2 solvent molecule.

« Un chaos savamment ordonné… ». L’élaboration conceptuelle de l’Exposition internationale japonaise en 2005

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Sophie Houdart

2007-06-01

Full Text Available  « Pas besoin de roman, Orsenna, ni même de nouvelles, moi je ne suis écrivain que de quelques mots. “Un chaos savamment ordonné de plantes, d’animaux et d’êtres humains”.Dites-moi, Orsenna, franchement, c’est bien ça une exposition coloniale : ça et rien que ça ?Alors [Gruvel] proposait à chaque séanceson chaos. […]Le chef de service proposait une descriptiondu palais des Colonies :“Derrière son élégante et pure colonnade, la haute façade apparaîtra tout entière transformée en une immense fr...

Préface

OpenAIRE

Tétreault, Sylvie

2017-01-01

Moi, mes souliers ont beaucoup voyagé.Ils m’ont porté de l’école à la guerre.J’ai traversé sur mes souliers ferrésLe monde et sa misère !Félix Leclerc, chanteur québécois (1914-1988)Moi mes souliers Depuis toujours, l’humain s’est déplacé au fil des saisons. Il a changé d’habitat pour avoir de meilleures conditions de vie et pour se mettre à l’abri de dangers potentiels. Aujourd’hui, de nombreuses personnes sont obligées de s’expatrier pour permettre à leurs enfants de grandir dans un pays sé...

Les premières années de The Himalayan Journal (1929-1940

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Michel Raspaud

2001-05-01

Full Text Available IntroductionLa création de The Himalayan Club, sur le territoire de l’Empire des Indes à la fin de l’année 1927, s’accompagne presque aussitôt de la publication de The Himalayan Journal, en février 1929, soit mois de dix-huit mois après la création officielle de l’institution. L’objet du présent texte concerne donc la vie de The Himalayan Club lors de ses premières années d’existence, depuis la date de sa création jusqu’au début de la seconde guerre mondiale. Cependant, l’intérêt se focaliser...

One-pot synthesis and antiproliferative activity of novel double-modified derivatives of the polyether ionophore monensin A.

Science.gov (United States)

Klejborowska, Greta; Maj, Ewa; Wietrzyk, Joanna; Stefańska, Joanna; Huczyński, Adam

2018-05-02

Monensin A (MON) is a polyether ionophore antibiotic, which shows a wide spectrum of biological activity. New MON derivatives such as double-modified ester-carbonates and double-modified amide-carbonates were obtained by a new and efficient one-pot synthesis with triphosgene as the activating reagent and the respective alcohol or amine. All new derivatives were tested for their antiproliferative activity against two drug-sensitive (MES-SA, LoVo) and two drug-resistant (MES-SA/DX5, LoVo/DX) cancer cell lines, and were also studied for their antimicrobial activity against different Staphylococcus aureus and Staphylococcus epidermidis bacterial strains. For the first time, the activity of MON and its derivatives against MES-SA and MES-SA/DX5 were evaluated. © 2018 John Wiley & Sons A/S.

Revolutionary Intelligence: The Expanding Intelligence Role of the Iranian Revolutionary Guard Corps

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Udit Banerjea

2015-09-01

Full Text Available The Iranian Revolutionary Guard Corps (IRGC is a military and paramilitary organization that is meant to defend the ideals of the Iranian Islamic Revolution in 1979. Since its formation, the IRGC has grown in influence and its intelligence role has expanded. This paper examines the role of the IRGC in Iran’s intelligence system through a comprehensive analysis of the organization of the IRGC’s intelligence arm, along with its operations and capabilities. In doing so, the scope, objectives, resources, customers, and sponsors of the IRGC’s intelligence activities are also analyzed. Additionally, this paper explores how the IRGC interacts with the government of Iran, the Ministry of Intelligence and Security (MOIS, other key internal stakeholders, and foreign client organizations. A key focus of this analysis is the evolution of the relationship between the IRGC and the MOIS and the growing influence of the IRGC in Iran’s intelligence community over the last decade. The paper concludes that the IRGC has now eclipsed the MOIS within Iran’s intelligence community and is one of the most powerful institutions in Iranian politics today, using its intelligence activities as its key means of maintaining power and influence within the country.

Autocatalytic caspase-3 driven by human telomerase reverse transcriptase promoter suppresses human ovarian carcinoma growth in vitro and in mice.

Science.gov (United States)

Song, Yue; Xia, Zhijun; Shen, Keng; Zhai, Xingyue

2013-05-01

To construct recombinant adenoviruses AdHT-rev-casp3 and Ad-rev-casp3, which express autocatalysis caspase-3 driven by human telomerase reverse transcriptase promoter and cytomegalovirus promoter, respectively; and to investigate their antitumor effects on ovarian cancer in vitro and in vivo. Cell viabilities were determined using the cell counting kit 8 and flow cytometry. Reverse transcriptase polymerase chain reaction and immunoblotting assays were used to detect cellular apoptotic activities after treatments. Tumor growth and survival of mice bearing AO cells were studied. AdHT-rev-casp3 significantly suppressed the survival of AO cells in a dose-dependent modality with a viability rate of 60.45% ± 7.8% at an multiplicity of infection (MOI) of 70 and 42.18 ± 5.3% at an MOI of 100, which was somewhat lower than that of the AO cells treated with Ad-rev-casp3 (32.28% ± 5.3% and 21.84% ± 3.4%, respectively). In contrast, AdHT-rev-casp3 induced little human umbilical vein epithelial cell (HUVEC) death with a viability rate of 98.52% ± 6.9% at an MOI of 70, whereas Ad-rev-casp3 induced significant cell death in HUVEC with a viability rate of 27.14% ± 5.4%. Additionally, AdHT-rev-casp3 (MOI = 70) caused significant apoptosis in AO cells with an apoptotic rate of 25.97%, whereas it caused undetectable apoptosis in HUVECs with the rate of only 1.75%. Ad-rev-casp3 (MOI = 70) caused strong apoptosis in both AO and HUVECs, with the rate of 35.82% and 38.12%, respectively. AdHT-rev-casp3 caused markedly higher levels of active caspase-3, causing no detectable active caspase-3 expression in HUVECs. The tumor growth suppression rate of AdHT-rev-casp3 was 54.94%, significantly higher than that of phosphate-buffered saline at the end point of the study. AdHT-rev-casp3 significantly improved the survival of mice receiving intraperitoneal inoculation of AO cells with little liver damage, with the mean survival of 177 ± 12 days. AdHT-rev-casp3 causes effective apoptosis

Administration des subventions du CRDI aux institutions :

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Comment puis-je réviser le budget de mon projet ? Le CRDI couvre-t-il les dépenses engagées en sus du montant de la subvention ? De quelle façon le CRDI transmet-il les fonds ? Mon institution doit-elle déposer les fonds reçus pour le projet dans un compte bancaire distinct ? Combien de temps faut-il au CRDI pour ...

Trap and soil monolith sampled edaphic spiders (arachnida: araneae in Araucaria angustifolia forest Aranhas (arachnida: araneae edáficas amostradas por armadilhas e monólitos de solo em florestas com Araucaria angustifolia

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Dilmar Baretta

2007-08-01

�reas: floresta nativa com predominância de araucária (NF; reflorestamento de araucária (R; reflorestamento de araucária submetido a incêndio acidental (RF; e pastagem natural com araucárias nativas e ocorrência de incêndio acidental (NPF. Considerando os dois métodos de amostragem (Monólito e armadilhas de solo, foram identificadas 20 famílias de aranhas associadas às áreas. O método das armadilhas de solo foi mais eficiente, capturando 19 das 20 famílias registradas, enquanto o do Monólito extraiu apenas dez destas famílias de aranhas. A abundância de famílias de aranhas e o índice de diversidade de Shannon (H foram afetados pelo método de coleta utilizado, sendo os valores destes atributos sempre superiores na NF e inferiores na NPF. A análise de correspondência (AC demonstrou que existe separação espacial entre as áreas estudadas. Sugere-se que as modificações na abundância de famílias de aranhas de solo sejam provocadas principalmente pelas intervenções antrópicas que as florestas de araucária vêm sofrendo nos últimos anos.

Au pont du trieur

CERN Document Server

Treille, Daniel

2016-01-01

Une existence qui bifurque, cela tient à très peu. » De son orphelinat népalais, une femme raconte les accidents de la vie qui l’ont menée d’une bourgade vosgienne à cet autre monde. Elle évoque ses premiers souvenirs d’enfance, de dramatiques épisodes de la guerre, son petit frère, la splendeur éphémère de leur famille d’industriels, sa révolte de jeune femme face à son redoutable grand-père. Ses tribulations parisiennes à la recherche de son frère disparu la mènent à rompre soudain avec une existence qu’elle n’aime plus pour partir en vivre une autre toute différente.

Aerobic pathogenic bacteria in post-operative wounds at Moi ...

African Journals Online (AJOL)

Background: The emergence of bacterial antimicrobial resistance associated with acquired infections has made the choice of empirical therapy more difficult and expensive, hence the need for continuous research to determine their sensitivity patterns. Objectives: To identify the common aerobic pathogenic bacteria in ...

Aerobic pathogenic bacteria in post-operative wounds at Moi ...

African Journals Online (AJOL)

Fullscreen Fullscreen Off. http://dx.doi.org/10.4314/eamj.v79i12.8671 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL · News. OTHER RESOURCES... for Researchers · for Journals ...

Childhood intussusception at the Moi teaching and referral hospital ...

African Journals Online (AJOL)

Fullscreen Fullscreen Off. http://dx.doi.org/10.4314/eamj.v81i9.9218 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL · News. OTHER RESOURCES... for Researchers · for Journals ...

Vietnam: Building and Sustaining People's Defense (Joint Force Quarterly, Issue 36)

National Research Council Canada - National Science Library

Van Tra, Pham

2004-01-01

In the fifteen years since the establishment of the national renewal policy, called doi moi, Vietnam has emerged from socioeconomic crisis characterized by extensive and debilitating rates of poverty...

Estimating fuel octane numbers from homogeneous gas-phase ignition delay times

KAUST Repository

Naser, Nimal

2017-11-05

Fuel octane numbers are directly related to the autoignition properties of fuel/air mixtures in spark ignition (SI) engines. This work presents a methodology to estimate the research and the motor octane numbers (RON and MON) from homogeneous gas-phase ignition delay time (IDT) data calculated at various pressures and temperatures. The hypothesis under investigation is that at specific conditions of pressure and temperature (i.e., RON-like and MON-like conditions), fuels with IDT identical to that of a primary reference fuel (PRF) have the same octane rating. To test this hypothesis, IDTs with a detailed gasoline surrogate chemical kinetic model have been calculated at various temperatures and pressures. From this dataset, temperatures that best represent RON and MON have been correlated at a specified pressure. Correlations for pressures in the range of 10–50 bar were obtained. The proposed correlations were validated with toluene reference fuels (TRF), toluene primary reference fuels (TPRF), ethanol reference fuels (ERF), PRFs and TPRFs with ethanol, and multi-component gasoline surrogate mixtures. The predicted RON and MON showed satisfactory accuracy against measurements obtained by the standard ASTM methods and blending rules, demonstrating that the present methodology can be a viable tool for a first approximation. The correlations were also validated against an extensive set of experimental IDT data obtained from literature with a high degree of accuracy in RON/MON prediction. Conditions in homogeneous reactors such as shock tubes and rapid compression machines that are relevant to modern SI engines were also identified. Uncertainty analysis of the proposed correlations with linear error propagation theory is also presented.

Management of Field-Evolved Resistance to Bt Maize in Argentina: A Multi-Institutional Approach

Science.gov (United States)

Signorini, Ana M.; Abratti, Gustavo; Grimi, Damián; Machado, Marcos; Bunge, Florencia F.; Parody, Betiana; Ramos, Laura; Cortese, Pablo; Vesprini, Facundo; Whelan, Agustina; Araujo, Mónica P.; Podworny, Mariano; Cadile, Alejandro; Malacarne, María F.

2018-01-01

Evolution of resistance to control measures in insect populations is a natural process, and management practices are intended to delay or mitigate resistance when it occurs. During the 2012/13 season the first reports of unexpected damage by Diatraea saccharalis on some Bt maize hybrids occurred in the northeast of San Luis province, Argentina. The affected Bt technologies were Herculex I® (HX-TC1507) and VT3PRO® (MON 89034 × MON 88017*). Event TC1507 expresses Cry1F and event MON 89034 expresses Cry1A.105 and Cry2Ab2, whichr are all Bt proteins with activity against the lepidopterans D. saccharalis and Spodoptera frugiperda (MON 88017 expresses the protein Cry3Bb1 for control of coleopteran insects and the enzyme CP4EPSPS for glyphosate tolerance). The affected area is an isolated region surrounded by sierra systems to the northeast and west, with a hot semi-arid climate, long frost-free period, warm winters, hot dry summers, and woody shrubs as native flora. To manage and mitigate the development of resistance, joint actions were taken by the industry, growers and Governmental Agencies. Hybrids expressing Vip3A protein (event MIR162) and/or Cry1Ab protein (events MON 810 and Bt11) as single or stacked events are used in early plantings to control the first generations of D. saccharalis, and in later plantings date's technologies with good control of S. frugiperda. A commitment was made to plant the refuge, and pest damage is monitored. As a result, maize production in the area is sustainable and profitable with yields above the average. PMID:29888224

Estimating fuel octane numbers from homogeneous gas-phase ignition delay times

KAUST Repository

Naser, Nimal; Sarathy, Mani; Chung, Suk-Ho

2017-01-01

Fuel octane numbers are directly related to the autoignition properties of fuel/air mixtures in spark ignition (SI) engines. This work presents a methodology to estimate the research and the motor octane numbers (RON and MON) from homogeneous gas-phase ignition delay time (IDT) data calculated at various pressures and temperatures. The hypothesis under investigation is that at specific conditions of pressure and temperature (i.e., RON-like and MON-like conditions), fuels with IDT identical to that of a primary reference fuel (PRF) have the same octane rating. To test this hypothesis, IDTs with a detailed gasoline surrogate chemical kinetic model have been calculated at various temperatures and pressures. From this dataset, temperatures that best represent RON and MON have been correlated at a specified pressure. Correlations for pressures in the range of 10–50 bar were obtained. The proposed correlations were validated with toluene reference fuels (TRF), toluene primary reference fuels (TPRF), ethanol reference fuels (ERF), PRFs and TPRFs with ethanol, and multi-component gasoline surrogate mixtures. The predicted RON and MON showed satisfactory accuracy against measurements obtained by the standard ASTM methods and blending rules, demonstrating that the present methodology can be a viable tool for a first approximation. The correlations were also validated against an extensive set of experimental IDT data obtained from literature with a high degree of accuracy in RON/MON prediction. Conditions in homogeneous reactors such as shock tubes and rapid compression machines that are relevant to modern SI engines were also identified. Uncertainty analysis of the proposed correlations with linear error propagation theory is also presented.

Slope activity in Gale crater, Mars

Science.gov (United States)

Dundas, Colin M.; McEwen, Alfred S.

2015-01-01

High-resolution repeat imaging of Aeolis Mons, the central mound in Gale crater, reveals active slope processes within tens of kilometers of the Curiosity rover. At one location near the base of northeastern Aeolis Mons, dozens of transient narrow lineae were observed, resembling features (Recurring Slope Lineae) that are potentially due to liquid water. However, the lineae faded and have not recurred in subsequent Mars years. Other small-scale slope activity is common, but has different spatial and temporal characteristics. We have not identified confirmed RSL, which Rummel et al. (Rummel, J.D. et al. [2014]. Astrobiology 14, 887–968) recommended be treated as potential special regions for planetary protection. Repeat images acquired as Curiosity approaches the base of Aeolis Mons could detect changes due to active slope processes, which could enable the rover to examine recently exposed material.

IBM-PC based high voltage controller [Paper No.: L7

International Nuclear Information System (INIS)

Mondal, N.K.; Kalmani, S.D.

1993-01-01

A simple IBM-PC/XT based high voltage controller is designed for C.A.E.N. high voltage supply unit, which is being used for testing the prototype detector for future accelerator experiment. The high voltage output of the supply unit can be remotely programmed. The V-set Lemo connectors at the rear panel provides the remote control facility. Similarly V-mon and I-mon can be used for remotely monitoring the voltage set and the current drawn from the supply unit. The controller described here sets the high voltage through V-set and monitors the voltage set, through V-mon at a pre-determined time interval. The monitoring is a background job and is done as an interrupt service routine of IRQ3. A simple menu driven software package used is written in Q-Basic and MASM. (author). 1 fig

Major Management Challenges and Program Risks: Small Business Administration

Science.gov (United States)

2001-01-01

2001 Major Management Challenges and Program Risks Small Business AdministrationGAO-01-260 Form SF298 Citation Data Report Date ("DD MON YYYY...34) 00JAN2001 Report Type N/A Dates Covered (from... to) ("DD MON YYYY") Title and Subtitle Major Management Challenges and Program Risks Small Business ...Administration (SBA) as it seeks to aid, counsel, assist, and protect the interests of the nations small businesses and help businesses and families

Discussion relating to the film "The Gospel according to St.Matthew"

CERN Multimedia

Christinger; Huber; Defelice; Crapon

1968-01-01

Plusieurs orateurs, le Sociologue à l'Université de Genève Christinger, le Révérend Père Cottier, le Pasteur Huber de l'Hôpital Cantonale de Genève, le député de la partie de travail Mons.Defelice et le traducteur Mons.Crapon parlent du film de Pasolini très discuté et se posent la question: pourquoi Pasolini a fait ce film? (but social, politique etc...)

Mon Amour, de Thomas Ferrand

OpenAIRE

Châtelet, Caroline

2018-01-01

Dans l’un de ses précédents spectacles, Extase de Sainte Machine, Thomas Ferrand mettait en scène deux comédiens dans un espace nu. Debout avec à leurs pieds un pack de bières, ceux-ci ne bougeaient pas, ne parlaient pas, seule l’intensité lumineuse et la musique amenant le mouvement. Proposition radicale par son atmosphère dérivant du contemplatif à l’hypnotisme, Extase de Sainte-Machine frôlait, aussi, une forme d’hermétisme. Comme si à vouloir travailler sur des états statiques, sur le mot...

Monóxido de carbono

Science.gov (United States)

La mayoria de los accidentes causados por envenenamiento por monoxido de carbono (CO) se producen en los hogares y estan relacionados a nuestras actividades diarias como cocinar y usar la calefaccion.

Skandaalne seksifilm takerdus rahapuudusesse / Jaan Väljaots

Index Scriptorium Estoniae

Väljaots, Jaan, 1968-

2001-01-01

Prantslaste Virginie Despentesè ja Coralie Trinh Thi mängufilm "Kepi mind" ("Baise-moi") pole "Sõpruse" kinos linastunud maaletooja Filmimax'i suutmatuse tõttu subtiitrifirmale "Baltlab" töö eest tasuda

Characterizing Center of Mass and Moment of Inertia of Soldiers' Loads Packed for Combat

National Research Council Canada - National Science Library

Hasselquist, Leif; Bensel, Carolyn K; Norton, Karen; Piscitelle, Louis; Schiffman, Jeffrey M

2004-01-01

...) location and moment of inertia (MOI) may be influenced in combat load packing. In addition, the physical properties of the combat loads were compared to the properties of a laboratory fabricated backpack...

Foire aux questions techniques concernant la Bourse du CRDI aux ...

International Development Research Centre (IDRC) Digital Library (Canada)

Un de mes professeurs n'a pas été en mesure de remplir à temps le formulaire lui permettant de donner des références à mon sujet. Par conséquent, je n'ai pas pu soumettre ma demande avant la date et l'heure butoirs. Est-ce que le formulaire de mon professeur peut être téléversé et soumis après la date et l'heure butoirs ...

The Genus Culex, Subgenus Eumelanomyia Theobald in Southeast Asia and Adjacent Areas

Science.gov (United States)

1972-01-01

Bore1 1930, Mon. Coil. Sot. Path. exot. 3: 365 (d*, ?, L*). Culex macropus Blanchard 1905, Les Moustiques :327. New name for Culex Zongifies Theobald...Spec. Pub. 111, 147 pp. BOREL, E. 1926. Les Moustiques de la Cochinchine et du Sud-Annam. (I), Arch. Inst. Pasteur d’Indochine. 47 pp. 1930. Les... Moustiques de la Cochinchine et du Sud-Annam. Mon. Coll. Sot. Pat. exot. 3, 423 pp. BRAM, R A. 1967. Contributions to the mosquitoes of Southeast Asia

Die Sprache des Marketings und ihre Übersetzung: Morphologische und semantische Aspekte der Terminologie

OpenAIRE

Konovalova, Anastasia; Ruiz Yepes, Guadalupe

2016-01-01

This article is the English version of “Die Sprache des Marketings und ihre Übersetzung: Morphologische und semantische Aspekte der Terminologie” by Anastasia Konovalova & Guadalupe Ruiz Yepes. It was not published on the print version of MonTI for reasons of space. The online version of MonTI does not suffer from these limitations, and this is our way of promoting plurilingualism. The importance of languages for special purposes in multinational companies grows with each passing day. Simu...

CCD polarimetry as a probe of regions of recent-star formation

Energy Technology Data Exchange (ETDEWEB)

Draper, P W

1988-01-01

Chapter 1 of this thesis details the incorporation of a Charged-Coupled Device (CCD) detector system with the Durham Imaging Polarimeter. The details include the physical characteristics of the device and the electronics and software associated with the device control and data storage. Chapter 2 of this work describes fully how suitable corrections for this effect can be made, and derives first-order results. The CCD performance is examined in comparison with the detector used previously and hence the veracity of the new results is established. Chapter 3 is a relevant summary of the status of the astronomy of the immediate regions of recent-star formation. Chapter 4 describes multicolor polarimetry of NGC2261/R Mon covering the period 1979 to 1986. The data conclusively prove that the polarization of R Mon must be due to effects close to R Mon (approx.14 astronomical units).

Structural and Nutritional Properties of Pasta from Triticum monococcum and Triticum durum Species. A Combined ¹H NMR, MRI, and Digestibility Study.

Science.gov (United States)

Pasini, Gabriella; Greco, Fulvia; Cremonini, Mauro A; Brandolini, Andrea; Consonni, Roberto; Gussoni, Maristella

2015-05-27

The aim of the present study was to characterize the structure of two different types of pasta, namely Triticum turgidum ssp. durum (cv. Saragolla) and Triticum monococcum ssp. monococcum (cv. Monlis), under different processing conditions. MRI analysis and NMR spectroscopy (i.e., T1 and T2 NMR relaxation times and diffusion parameters) were conducted on pasta, and (1)H NMR spectroscopic analysis of the chemical compounds released by pasta samples during the cooking process was performed. In addition, starch digestibility (enzimatically determined) was also investigated. The NMR results indicated that Saragolla pasta has a more compact structure, ascribed to pasta network and in particular to different technological gluten properties, that mainly determine the lower ability of Monlis pasta in binding water. These results correlate well with the lower rate of starch hydrolysis measured for Monlis pasta compared to Saragolla when both are dried at high temperature.

Development and interlaboratory validation of quantitative polymerase chain reaction method for screening analysis of genetically modified soybeans.

Science.gov (United States)

Takabatake, Reona; Onishi, Mari; Koiwa, Tomohiro; Futo, Satoshi; Minegishi, Yasutaka; Akiyama, Hiroshi; Teshima, Reiko; Kurashima, Takeyo; Mano, Junichi; Furui, Satoshi; Kitta, Kazumi

2013-01-01

A novel real-time polymerase chain reaction (PCR)-based quantitative screening method was developed for three genetically modified soybeans: RRS, A2704-12, and MON89788. The 35S promoter (P35S) of cauliflower mosaic virus is introduced into RRS and A2704-12 but not MON89788. We then designed a screening method comprised of the combination of the quantification of P35S and the event-specific quantification of MON89788. The conversion factor (Cf) required to convert the amount of a genetically modified organism (GMO) from a copy number ratio to a weight ratio was determined experimentally. The trueness and precision were evaluated as the bias and reproducibility of relative standard deviation (RSDR), respectively. The determined RSDR values for the method were less than 25% for both targets. We consider that the developed method would be suitable for the simple detection and approximate quantification of GMO.

Climatological variability in modeling of long-term regional transport and deposition of air pollutants

International Nuclear Information System (INIS)

Shannon, J.D.

1984-01-01

In a growing number of emission policy analyses, regulatory proceedings, and cost/benefit assessments, numerical models of long-range transport and deposition of air pollutants have been exercised to estimate source-receptor (S-R) relationships--for the particular meteorological conditions input to the model. The representativeness of the meteorological conditions, or the variability of the model estimates with climatological input from different years or corresponding seasons from different years, is seldom evaluated. Here, two full years (1980 and 1981) of meteorological data, as well as data from January and July of 1978, are used in the Advanced Statistical Trajectory Regional Air Pollution (ASTRAP) model (Shannon, 1981), one of the eight Memorandum of Intent (MOI) models, to estimate deposition for the S-R matrix combination of eleven source regions and nine receptors used in the MOI reports. (S-R matrices of dimensions 40 by 9 were also examined in the MOI reports.) Improvements in the ASTRAP model and in the emission inventory since the earlier work require recalculation of the two-month 1978 simulation in order for the comparison to isolate the effect of meteorological variability. The source regions are listed, and the receptor regions are provide. For completeness, an additional source region, the western states and provinces, has been added, as well as a total for the 48 contiguous states and 10 provinces. 4 references, 9 tables

Metàfores visuals en els mons virtuals. El cas de NANEC 2010-11 Visual Metaphors in Virtual Worlds. The Example of NANEC 2010-11 Metáforas visuales en mundos virtuales. El caso de NANEC 2010-11

Directory of Open Access Journals (Sweden)

Dolors Capdet

2011-06-01

Full Text Available Abans de la invenció de la impremta la narració oral d'històries era la gran transmisora del coneixement. La impremta va atorgar velocitat i perennitat a la narració, ampliant el temps per a la seva reflexió. Amb Internet es fragmenta la seqü.ncialitat del missatge i és possible crear noves realitats que poden tenir o no el seu referent al món real. Els mons virtuals en són un clar exemple.Before the invention of printing, the storytelling was the great transmitter of knowledge. The print brings speed and continuity to narrative and extending the time for their reflection. With Internet is fragmented the message sequentiality and may be create new realities with referent in the real world or not. Virtual worlds are a clear example.Antes de la invención de la imprenta la narración oral de historias era la gran transmisora del conocimiento. La imprenta otorgó velocidad y perennidad a la narración, ampliando el tiempo para su reflexión. Con Internet se fragmenta la secuencialidad del mensaje y es posible crear nuevas realidades que pueden tener o no su referente en el mundo real. Los mundos virtuales son un claro ejemplo de ello. 

The nature of dark matter

Energy Technology Data Exchange (ETDEWEB)

Kirillov, A.A. [Institute for Applied Mathematics and Cybernetics, 10 Uljanova Str., Nizhny Novgorod 603005 (Russian Federation)]. E-mail: ka98@mail.ru

2006-01-19

The observed strong dark-to-luminous matter coupling [F. Donato, et al., astro-ph/0403206, Mon. Not. R. Astron. Soc., submitted for publication; G. Gentile, et al., Mon. Not. R. Astron. Soc. 351 (2004) 903; D.T.F. Weldrake, et al., Mon. Not. R. Astron. Soc. 340 (2003) 12; W.J.G. de Blok, A. Bosma, Astron. Astrophys. 385 (2002) 816; O. Gerhard, et al., Astrophys. J. 121 (2001) 1936; A. Borriello, et al., Mon. Not. R. Astron. Soc. 341 (2003) 1109] suggests the existence of a some functional relation between visible and DM sources which leads to biased Einstein equations. We show that such a bias appears in the case when the topological structure of the actual Universe at very large distances does not match properly that of the Friedman space. We introduce a bias operator {rho}{sub DM}=B-bar {rho}{sub vis} and show that the simple bias function b=1/(4{pi}r{sub 0}r{sup 2}){theta}(r-r{sub max}) (the kernel of B-bar ) allows to account for all the variety of observed DM halos in astrophysical systems. In galaxies such a bias forms the cored DM distribution with the radius R{sub C}{approx}R{sub opt} (which explains the recently observed strong correlation between R{sub C} and R{sub opt} [F. Donato, et al., astro-ph/0403206, Mon. Not. R. Astron. Soc., submitted for publication]), while for a point source it produces the logarithmic correction to the Newton's potential (which explains the observed flat rotation curves in spirals). Finally, we show that in the theory suggested the galaxy formation process leads to a specific variation with time of all interaction constants and, in particular, of the fine structure constant.

Effects of an Ionophore Coccidiostat (Monensin or Salinomycin, Sodium or Potassium Bicarbonate, or Both, and Bacitracin Methylene Disalicylate in Broiler Chicken Diets

Directory of Open Access Journals (Sweden)

Hooge DM

2000-01-01

Full Text Available Peterson x Arbor Acres chicks were grown on used litter to 45 or 46 days of age in three pen trials. Coccidial inoculations were given by water at 14 days of age. Sodium bicarbonate (SBC; 0.20% or potassium bicarbonate (PBC; 0.14% was added to broiler chicken diets containing monensin (MON; 110 mg/kg or salinomycin (SAL; 66 mg/kg in Experiment 1. In Experiment 2, using SAL (55 mg/kg, three dietary bicarbonate treatments (SBC, 0.20%; PBC, 0.20%; or SBC + PBC 0.10% each were tested with or without BMD R (55 mg/kg. Diets differing in SAL, BMD R, and SBC levels were evaluated in Experiment 3. Beneficial interaction was found between ionophores and bicarbonates for mortality (lower when SBC or PBC and MON in Experiment 1. For main effects, in Experiment 1 PBC with MON or SAL improved body weight, feed conversion ratio and mortality. SAL improved weight, feed conversion ratio and mortality compared to MON. In Experiment 2, PBC with SAL improved weight, coccidial lesion score, feed conversion ratio and mortality across two levels of BMD R. The PBC and SBC were equally effective in Experiment 1, but PBC was about 0 to 40% as effective as SBC, depending on parameter in Experiment 2. Half levels of SBC plus PBC generally gave intermediate results between control and SBC. SBC with MON or SAL lowered mortalities, coccidial lesion scores, and feed conversion ratios (Experiments 1 and 2, and increased body weight (Experiment 2. In Experiment 3, BMD R in all feeds improved body weight and feed conversion versus in starter feed only, and SBC with SAL and BMD R improved all performance parameters.

Comparison of Human Sodium/Iodide Symporter (hNIS) Gene Expressions between Lentiviral and Adenoviral Vectors in Rat Mesenchymal Stem Cells

International Nuclear Information System (INIS)

Park, So Yeon; Lee, Won Woo; Kim, Hyun Joo; Chung, June Key; Kim, Sang Eun; Kim, Sung Jin; Lee, Heui Ran

2008-01-01

Quantitative comparison of transgene expression within stem cells between lentivirus and adenovirusmediated delivery systems has not been reported. Here, we evaluated the human sodium iodide symporter (hNIS) gene expression in rat mesenchymal stem cell (rMSC) transduced by lentivirus or adenovirus, and compared the hNIS expression quantitatively between the two delivery systems. Lentiviral-mediated hNIS expressing rMSC (lenti-hNIS-rMSC) was constructed by cloning hNIS gene into pLenti6/UbC/V5-DEST (Invitrogen) to obtain pLenti-hNIS, transducing rMSC with the pLenti-hNIS, and selecting with blasticidin for 3 weeks. Recombinant adenovirus expressing hNIS gene (Rad-hNIS) was produced by homologous recombination and transduction efficiency of Rad-hNIS into rMSC evaluated by Rad-GFP was 19.1±4.7%, 54.0±6.4%, 85.7±8.7%, and 98.4±1.3% at MOI 1, 5, 20, and 100, respectively. The hNIS expressions in lenti-hNIS-rMSC or adeno-hNIS-rMSC were assessed by immunocytochemistry, western blot, and I-125 uptake. Immunocytochemistry and western blot analyses revealed that hNIS expressions in lenti-hNIS-rMSC were greater than those in adeno-hNIS-rMSC at MOI 20 but lower than at MOI 50. However in vitro I-125 uptake test demonstrated that iodide uptake in lenti-hNIS-rMSC (29,704±6,659 picomole/10 6 cells) was greater than that in adeno-hNIS-rMSC at MOI 100 (6,168±2,134 picomole/10 6 cells). Despite lower amount of expressed protein, hNIS function in rMSC was greater by lentivirus than by adenovirus mediated expression. Stem cell tracking using hNIS as a reporter gene should be conducted in consideration of relative vector efficiency for transgene expression

Malaria case clinical profiles and Plasmodium falciparum parasite genetic diversity: a cross sectional survey at two sites of different malaria transmission intensities in Rwanda.

Science.gov (United States)

Kateera, Fredrick; Nsobya, Sam L; Tukwasibwe, Stephen; Mens, Petra F; Hakizimana, Emmanuel; Grobusch, Martin P; Mutesa, Leon; Kumar, Nirbhay; van Vugt, Michele

2016-04-26

Malaria remains a public health challenge in sub-Saharan Africa with Plasmodium falciparum being the principal cause of malaria disease morbidity and mortality. Plasmodium falciparum virulence is attributed, in part, to its population-level genetic diversity-a characteristic that has yet to be studied in Rwanda. Characterizing P. falciparum molecular epidemiology in an area is needed for a better understand of malaria transmission and to inform choice of malaria control strategies. In this health-facility based survey, malaria case clinical profiles and parasite densities as well as parasite genetic diversity were compared among P. falciparum-infected patients identified at two sites of different malaria transmission intensities in Rwanda. Data on demographics and clinical features and finger-prick blood samples for microscopy and parasite genotyping were collected(.) Nested PCR was used to genotype msp-2 alleles of FC27 and 3D7. Patients' variables of age group, sex, fever (both by patient report and by measured tympanic temperatures), parasite density, and bed net use were found differentially distributed between the higher endemic (Ruhuha) and lower endemic (Mubuga) sites. Overall multiplicity of P. falciparum infection (MOI) was 1.73 but with mean MOI found to vary significantly between 2.13 at Ruhuha and 1.29 at Mubuga (p < 0.0001). At Ruhuha, expected heterozygosity (EH) for FC27 and 3D7 alleles were 0.62 and 0.49, respectively, whilst at Mubuga, EH for FC27 and 3D7 were 0.26 and 0.28, respectively. In this study, a higher geometrical mean parasite counts, more polyclonal infections, higher MOI, and higher allelic frequency were observed at the higher malaria-endemic (Ruhuha) compared to the lower malaria-endemic (Mubuga) area. These differences in malaria risk and MOI should be considered when choosing setting-specific malaria control strategies, assessing p. falciparum associated parameters such as drug resistance, immunity and impact of used

Camille Laurens, Marie Darrieussecq : du « plagiat psychique » à la mise en questions de la démarche autobiographique

Directory of Open Access Journals (Sweden)

Anne Strasser

2012-04-01

Full Text Available À l’automne 2007, Camille Laurens a accusé Marie Darrieussecq de « plagiat psychique », lui reprochant d’avoir « piraté » son récit autobiographique, Philippe, pour écrire un roman, Tom est mort. Au cœur de ces deux récits, la mort d’un enfant racontée du point de vue de la mère. Au-delà des similitudes relevées par Camille Laurens, cette dernière a dénié le droit à Marie Darrieussecq d’avoir raconté la mort d’un enfant alors qu’elle ne l’avait pas elle-même vécue. Cette querelle s’est jouée par écrits interposés, articles, roman, essai. L’étude des arguments des deux parties montrera que le questionnement est multiple : il vise le genre choisi, le sujet traité et l’énonciation. La querelle témoigne du brouillage des genres, de la moralisation de la littérature et d’une certaine forme de sacralisation de la souffrance. In fall 2007, Camille Laurens accused Marie Darrieussecq of « physical plagiarism », blaming her for pirating her autobiographical story, Philippe, to write a novel, Tom is Dead. At the heart of these two stories, the death of a child is told from the mother’s point of view. Beyond the similarities noticed by Camille Laurens, the latter denies Marie Darrieussecq the right to tell about the death of a child whereas she had not lived through it herself. This quarrel happened through written work, articles, novels and essays. The study of the arguments given by each party shows that there are several things to question: it is about the genre, the subject and the enunciation. It is a very contemporary quarrel since it shows how blurred genres are, how moralizing literature has become and how suffering has been made sacred in a certain way.

Preparation and supercapacitance performance of manganese oxide nanosheets/graphene/carbon nanotubes ternary composite film

International Nuclear Information System (INIS)

Tang, Qianqiu; Sun, Minqiang; Yu, Shuangmin; Wang, Gengchao

2014-01-01

Graphical abstract: - Highlights: • The MnO 2 nanosheets/graphene/MWCNT composite film with a porous sandwich structure was fabricated through a filtration-directed self-assembly. • The introduction of graphene and MWCNT restricts dense stacking of MnO 2 nanosheets. • Ternary composite film exhibits impressive electrochemical performance compared to pure MnO 2 nanosheets. - Abstract: A novel MnO 2 nanosheets/graphene nanosheets/carboxylic multi-walled carbon nanotubes (MONS/GNS/cMWCNT) ternary composite film was fabricated through a filtration-directed self-assembly method. The Field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM) images showed the porous sandwiched structure of MONS/GNS/cMWCNT with GNS providing a conductive substrate and cMWCNT functioning as a vertical electron pathway. The X-ray diffraction (XRD) and Raman spectra further confirmed that the introduction of GNS and cMWCNT restricted the serious aggregation of MONS, resulting in a higher specific area (691 m 2 g −1 ). As a result, the MONS/GNS/cMWCNT composite film exhibited higher specific capacitance (248 Fg −1 at 1 Ag −1 in 1 M Na 2 SO 4 ), better rate performance (66.9% capacitance retention from 0.2 to 10 Ag −1 ) and cycling stability (86.5% retention after 3000 cycles) compared with those of pure dried MnO 2 nanosheets

Annals of African Surgery July 2011 07.12.2011.indd

African Journals Online (AJOL)

andrew

2011-07-12

30100, Eldoret, Kenya, E–mail: lklelei@yahoo.com ... among in-patients at Moi Teaching and Referral Hospital (MTRH), ... within the catchment area use firewood for cooking. ... and costs from cigarettes lights, a global overview.

Opinion

African Journals Online (AJOL)

abp

2012-06-21

Jun 21, 2012 ... In Kenya, universities offering undergraduate training in medicine include the university of Nairobi and Moi .... road traffic accident. .... more knowledgeable about its pharmacology but because they have the solution that will.

« Moitié d’homme » dans les contes de tradition orale

OpenAIRE

Belmont, Nicole

2005-01-01

Le conte intitulé « Le Garçon paresseux » (conte-type 675 de la typologie internationale) est répandu dans toute l’Europe. Son héros est un être défavorisé à tous égards qui réussit cependant à épouser la fille du roi. Certaines versions en font même une moitié d’homme, expliquant parfois cette incomplétude par un vœu imprudent du père ou de la mère. Si, comme le dit Freud, « le moi est avant tout un moi corporel », il s’agit pour le héros d’acquérir son identité plénière, et en particulier s...

Lognormal Behavior of the Size Distributions of Animation Characters

Science.gov (United States)

Yamamoto, Ken

This study investigates the statistical property of the character sizes of animation, superhero series, and video game. By using online databases of Pokémon (video game) and Power Rangers (superhero series), the height and weight distributions are constructed, and we find that the weight distributions of Pokémon and Zords (robots in Power Rangers) follow the lognormal distribution in common. For the theoretical mechanism of this lognormal behavior, the combination of the normal distribution and the Weber-Fechner law is proposed.

The SFMOMA AR Game Jam

DEFF Research Database (Denmark)

Brin, Sarah; Gangsei, Erica

2018-01-01

In the Summer of 2016, Pokémon Go precipitated a surge of new play experiences in museums. Cultural heritage institutions across disciplines were confronted with the sudden ubiquity of augmented reality (AR). Some museums enthusiastically integrated Pokémon into their programs, while some grapple......, and Rebecca Edwards. “Night at the Museum: The 2016 Getty/USC Game Jam.” Blog. The Getty Iris, March 31, 2016. http://blogs.getty.edu/iris/a-night-at-themuseum-the-2016-gettyusc-game-jam/....

Risques, lumières et obscurités: les éclairages de l’humanisme méthodologique

Directory of Open Access Journals (Sweden)

Roger Nifle

2015-09-01

Full Text Available Comme toute chose, pour les hommes, le risque s'entend en plusieurs Sens, comme aussi ils se le disent et se le racontent. Voilà posés les repères de l'Humanisme Méthodologique et son anthropologie fondamentale. Il y a risque là où l'hypothèse d'un dommage est envisagée. Mais cette hypothèse est une spéculation puisque si le dommage se produit alors le risque comme anticipation n'est plus ou pas le même, pouvant toujours en spéculer une autre. Pas d'imaginaire pas de risque. On dira volontiers inconscient celui qui ne voit pas ou ne mesure pas le risque tel qu'il est. Mais il n'est que dans la spéculation.

PATTERNS OF SEVEN AND COMPLICATED MALARIA IN CHILDREN

African Journals Online (AJOL)

GB

2012-11-03

Nov 3, 2012 ... The objective of this study was to assess patients' satisfaction with their outpatient visit to .... National Hospital and Moi Referral Hospital were excluded from this ..... Kenya Health. Sector: Customer Satisfaction Survey Report.

Socioeconomic Renovation in Viet Nam: The Origin, Evolution, and ...

International Development Research Centre (IDRC) Digital Library (Canada)

Referred to as doi moi, this "renovation" has produced dramatic changes in ... In this book, Vietnamese scholars describe the origins and impacts of these changes. ... for two Colombian cities were discussed at ADAPTO's second international ...

the anatomy of pelvic corona mortis vessles in black africans

African Journals Online (AJOL)

, Moi University, P. O. Box ... This vascular anastomosis is also at risk during ilionguinal approach to the acetabulum (7). A medial approach for pelvic osteotomies for acetabular dysplasia ..... Gray's Anatomy 39th Edition , section 7 abdomen.

Evaluating engrailed-2 and cytokines in urine with serum PSA as ...

African Journals Online (AJOL)

Evaluating engrailed-2 and cytokines in urine with serum PSA as potential biomarkers in patients with prostatism at Moi Teaching and Referral Hospital, Eldoret, Kenya. B Donald-Buri, K Patel, P Musau, E.N. Fish ...

Eksperdid hakkavad arutama "Kepi mind" pornograafilisust

Index Scriptorium Estoniae

2001-01-01

Mitmes riigis keelatud prantsuse mängufilmi "Kepi mind" ("Baise-moi") näitamise eest "Sõpruse" kinos võib filmi maaletoojat Filmimaxi oodata karistus rahatrahvi näol, kui kultuuriministeeriumi juures tegutsev ekspertkomisjon tunnistab filmi pornograafiliseks

East African Medical Journal - Vol 81, No 8 (2004)

African Journals Online (AJOL)

economic factors predisposing under five-year-old children to Severe protein energy malnutrition at the Moi teaching and referral hospital, Eldoret, Kenya · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD ...

Kinos "Sõprus" linastub film "Kepi mind"

Index Scriptorium Estoniae

2001-01-01

Virginie Despentesè ja Coralie Trinh Thi mängufilm "Kepi mind" ("Baise-moi") : Prantsusmaa 1999. Maaletoojal firmal Filmimax ja kinol "Sõprus" on oodata ebameeldivusi filmi väidetavalt pornograafilise ja vägivaldse sisu tõttu

A blending rule for octane numbers of PRFs and TPRFs with ethanol

KAUST Repository

AlRamadan, Abdullah S.

2016-04-12

Ethanol is widely used as an octane booster in commercial gasoline fuels. Its oxygenated nature aids in reducing harmful emissions such as nitric oxides (NOx), soot and unburned hydrocarbons (HC). However, the non-linear octane response of ethanol blending with gasoline fuels is not completely understood because of the unknown intermolecular interactions in such blends. In general, when ethanol is blended with gasoline, the Research Octane Number (RON) and the Motor Octane Number (MON) non-linearly increase (synergistic) or decrease (antagonistic), and the non-linearity depends on the composition of the base gasoline. The complexity of commercial gasoline, comprising of hundreds of different components, makes it challenging to understand ethanol-gasoline synergistic/antagonistic blending effects. Understanding ethanol blending effects with simpler gasoline surrogates blends may enable a better understanding of ethanol blending with complex multi-component gasoline fuels. This study presents a blending rule to predict the octane numbers (ON) of ethanol/primary reference fuel (PRF; mixtures of iso-octane and n-heptane) and ethanol/toluene primary reference fuel (TPRF; mixtures of toluene, iso-octane and n-heptane) mixtures using the data available in literature and new data. The ON of ethanol blends with PRF-40, -50, and -60 were measured and compared with those from literature. Additional experimental data were collected to validate the developed model for ethanol blends of three different TPRFs having the same RON but different MON (i.e., different toluene contents). The three tested TPRF mixtures have octane ratings of RON 60.0/MON 58.0 (toluene 10.2 vol%), RON 60.0/MON 56.3 (toluene 19.8 vol%), and RON 60.0/MON 53.2 (toluene 40.2 vol%). The octane prediction model consists of linear and non-linear by mole regions. The transition point between the linear and non-linear regions is a function of the RON and MON of the base PRF and TPRF mixture. The non-linear by

Influence of additional language learning on first language learning in children with language disorders.

Science.gov (United States)

To, Carol K S; Law, Thomas; Li, Xin-xin

2012-01-01

Multilingualism can bring about various positive outcomes to typically developing children. Its effect on children with language difficulties is not yet clear. The aim of this study was to examine the effects of multilingual learning as a medium of instruction (MOI) on first language (L1) acquisition of children with language disorders (LD). Nineteen Cantonese-speaking students aged 5;8-6;8 who were diagnosed with LD were recruited from a school that used Putonghua (an alternative Chinese dialect) as the MOI when learning Chinese language and were compared with 18 age-and-gender-matched Cantonese-speaking students with LD from a school that used Cantonese as the MOI when learning Chinese language. All the students also learned English (L2) as a subject at school. Proficiency in Cantonese was tested at the beginning and the end of the semester in Grade One in terms of: (1) grammar, (2) expressive vocabulary, (3) auditory textual comprehension, (4) word definition and (5) narration. Mixed-model ANOVAs revealed an effect of time on language proficiency indicating positive gains in both groups. Interaction effects between time and group were not significant. There was a trend that children learning Putonghua showed slightly more improvement in auditory textual comprehension. Proficiency gains were similar across groups. The study found no evidence that a multilingual learning environment hinders the language proficiency in L1 in students who have LD. © 2011 Royal College of Speech and Language Therapists.

The presence of p53 influences the expression of multiple human cytomegalovirus genes at early times postinfection.

Science.gov (United States)

Hannemann, Holger; Rosenke, Kyle; O'Dowd, John M; Fortunato, Elizabeth A

2009-05-01

Human cytomegalovirus (HCMV) is a common cause of morbidity and mortality in immunocompromised and immunosuppressed individuals. During infection, HCMV is known to employ host transcription factors to facilitate viral gene expression. To further understand the previously observed delay in viral replication and protein expression in p53 knockout cells, we conducted microarray analyses of p53(+/+) and p53(-/-) immortalized fibroblast cell lines. At a multiplicity of infection (MOI) of 1 at 24 h postinfection (p.i.), the expression of 22 viral genes was affected by the absence of p53. Eleven of these 22 genes (group 1) were examined by real-time reverse transcriptase, or quantitative, PCR (q-PCR). Additionally, five genes previously determined to have p53 bound to their nearest p53-responsive elements (group 2) and three control genes without p53 binding sites in their upstream sequences (group 3) were also examined. At an MOI of 1, >3-fold regulation was found for five group 1 genes. The expression of group 2 and 3 genes was not changed. At an MOI of 5, all genes from group 1 and four of five genes from group 2 were found to be regulated. The expression of control genes from group 3 remained unchanged. A q-PCR time course of four genes revealed that p53 influences viral gene expression most at immediate-early and early times p.i., suggesting a mechanism for the reduced and delayed production of virions in p53(-/-) cells.

Rotating NSs/QSs and recent astrophysical observations

International Nuclear Information System (INIS)

Li, Ang; Dong, Jianmin

2017-01-01

Both fast and slow configurations of rotating neutron stars (NSs) are studied with the recently-constructed unified NS EoSs. The calculations for pure quark stars (QSs) and hybrid stars (HSs) are also done, using several updated quark matter EoSs and Gibbs construction for obtaining hadron-quark mixed phase. All three types of EoSs fulfill the recent 2-solar-mass constraint. By confronting the glitch observations with the theoretical calculations for the crustal moment of inertia (MoI), we find that the glitch crisis is still present in Vela-like pulsars. An upcoming accurate MoI measurement (eg., a possible 10% accuracy for pulsar PSR J0737–3039A) allows one to distinguish QSs from NSs, since the MoIs of QSs are generally ≳ 1.5 times larger than NSs and HSs, no matter the compactness and the mass of the stars. Using tabulated EoSs, we compute stationary and equilibrium sequences of rapidly rotating, relativistic stars in general relativity from the well-tested rns code, assuming the matter comprising the star to be a perfect fluid. All three observed properties of the short gamma-ray bursts (SGRBs) internal plateaus sample are simulated using the rotating configurations of NSs/QSs as basic inputs. We finally argue that for some characteristic SGRBs, the post-merger products of NS-NS mergers are probably supramassive QSs rather than NSs, and NS-NS mergers are a plausible location for quark deconfinement and the formation of QSs. (paper)

77 FR 69838 - MON 87410 and MON 87411 Pesticide-Incorporated Protectant Corn Events: Pesticide Experimental Use...

Science.gov (United States)

2012-11-21

... FURTHER INFORMATION CONTACT: Shanaz Bacchus, Biopesticides and Pollution Prevention Division (7511P..., Keith Matthews, Director, Biopesticides and Pollution Prevention Division, Office of Pesticide Programs...

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African Journals Online (AJOL)

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mother, child health and family planning clinics in Eldoret, Kenya. *Were E1, Nyaberi Z 2, ... cancer seen at the Moi Teaching and Referral Hospital. (MTRH). ..... the effect of risk factors. .... included race, socioeconomic status, chronic infections ...

prevalence, treatment and control of hypertension among type 2

African Journals Online (AJOL)

2014-08-01

Aug 1, 2014 ... type 2 diabetic patients at Moi Teaching and Referral Hospital (MTRH) and to determine predictors of blood ... forces of CVD in LIC are hypertension and diabetes (1). Type 2 ... Based on the American Diabetes Association.

Titulaires de la bourse du CRDI aux chercheurs candidats au ...

International Development Research Centre (IDRC) Digital Library (Canada)

Université d'Ottawa, doctorat en développement international. ... The role of traditional actors in taxation in Sierra Leone: Unorthodox public-private ... Abonnez-vous à notre bulletin pour recevoir les nouvelles du CRDI chaque mois. Abonnez- ...

Ecohealth Interventions for Chagas Disease Prevention in Central ...

International Development Research Centre (IDRC) Digital Library (Canada)

... 10 million people in the region are infected by the parasite Trypanosoma Cruzi. ... from human to chicken blood meals (chickens do not transmit the disease). ... pour recevoir des nouvelles et des articles d'opinion du CRDI chaque mois.

Confirmation of a predicted lack of IgE binding to Cry3Bb1 from genetically modified (GM) crops.

Science.gov (United States)

Nakajima, Osamu; Koyano, Satoru; Akiyama, Hiroshi; Sawada, Jun-Ichi; Teshima, Reiko

2010-04-01

Some GM crops including MON863 corn and stack varieties contain Cry3Bb1 protein. Cry3Bb1 is very important from the standpoint of assessing the safety of GM crops. In this study Cry3Bb1 was assessed from the standpoint of possible binding to IgE from allergy patients. First, an ELISA that was improved in our laboratory was used to test serum samples from 13 corn allergy patients in the United States with recombinant Cry3Bb1 expressed in Escherichia coli, and serum samples from 55 patients in Japan with various food allergies were also assayed. Two samples from the Japanese allergy patients were suspected of being positive, but Western blotting analysis with purified Cry3Bb1 indicated that the binding between IgE and Cry3Bb1 was nonspecific. Ultimately, no specific binding between IgE and recombinant Cry3Bb1 was detected. Next, all proteins extracted from MON863 corn and non-GM corn were probed with IgE antibodies in serum samples from the corn allergy patients by Western blotting, but the staining patterns of MON863 and non-GM corn were similar, meaning that unintended allergic reactions to MON863 are unlikely to occur. Our study provides additional information that confirms the predicted lack of IgE binding to Cry3Bb1 in people with existing food allergies. Copyright 2009 Elsevier Inc. All rights reserved.